Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002631-TA|BGIBMGA002631-PA|IPR003591|Leucine-rich
repeat, typical subtype, IPR000483|Cysteine-rich flanking region,
C-terminal, IPR001611|Leucine-rich repeat
(565 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 124 8e-28
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 124 8e-28
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 111 5e-24
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 111 5e-24
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 111 5e-24
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 111 5e-24
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 107 8e-23
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 107 8e-23
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 107 1e-22
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 107 1e-22
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 105 3e-22
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 103 2e-21
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 103 2e-21
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 103 2e-21
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 102 4e-21
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 102 4e-21
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 102 4e-21
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 99 2e-20
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 100 3e-20
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 100 3e-20
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 100 3e-20
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 99 5e-20
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 99 5e-20
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 99 5e-20
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 99 5e-20
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 98 6e-20
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 98 6e-20
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 98 6e-20
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 98 6e-20
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 98 6e-20
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 98 6e-20
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 98 6e-20
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 98 8e-20
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 98 8e-20
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 97 1e-19
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 97 1e-19
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 97 1e-19
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 97 1e-19
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 97 2e-19
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 97 2e-19
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 96 3e-19
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 95 6e-19
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 95 8e-19
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 93 2e-18
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 92 5e-18
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 91 7e-18
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 91 7e-18
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 91 7e-18
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 91 7e-18
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 91 1e-17
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 91 1e-17
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 91 1e-17
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 91 1e-17
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 91 1e-17
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 91 1e-17
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 91 1e-17
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 90 2e-17
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 90 2e-17
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 90 2e-17
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 90 2e-17
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 90 2e-17
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 90 2e-17
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 90 2e-17
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 90 2e-17
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 87 1e-16
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 87 1e-16
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 87 1e-16
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 87 1e-16
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 87 2e-16
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 87 2e-16
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 86 4e-16
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 86 4e-16
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 86 4e-16
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 86 4e-16
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 86 4e-16
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 86 4e-16
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 86 4e-16
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 86 4e-16
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 86 4e-16
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 86 4e-16
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 86 4e-16
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 86 4e-16
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 84 1e-15
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 84 1e-15
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 84 1e-15
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 84 1e-15
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 84 1e-15
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 84 1e-15
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 83 2e-15
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 83 2e-15
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 83 2e-15
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 83 3e-15
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 83 3e-15
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 83 3e-15
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 82 4e-15
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 82 4e-15
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 82 4e-15
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 82 6e-15
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 82 6e-15
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 81 8e-15
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 81 8e-15
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 81 8e-15
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 81 8e-15
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 81 8e-15
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 81 1e-14
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 81 1e-14
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 81 1e-14
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 81 1e-14
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 81 1e-14
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 81 1e-14
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 81 1e-14
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 81 1e-14
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 81 1e-14
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 81 1e-14
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 81 1e-14
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 81 1e-14
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 81 1e-14
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 81 1e-14
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 81 1e-14
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 80 2e-14
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 79 3e-14
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 79 3e-14
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 79 3e-14
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 79 3e-14
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 79 4e-14
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 79 4e-14
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 79 4e-14
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 78 7e-14
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 78 7e-14
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 78 7e-14
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 77 2e-13
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 76 3e-13
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 76 3e-13
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 76 3e-13
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 76 3e-13
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 76 4e-13
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 76 4e-13
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 76 4e-13
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 76 4e-13
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 76 4e-13
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 76 4e-13
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 75 5e-13
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 75 5e-13
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 75 5e-13
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 75 5e-13
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 75 7e-13
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 75 7e-13
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 75 7e-13
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 75 7e-13
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 75 7e-13
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 75 7e-13
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 75 7e-13
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 75 7e-13
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 75 9e-13
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 75 9e-13
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 75 9e-13
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 74 2e-12
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 74 2e-12
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 74 2e-12
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 74 2e-12
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 74 2e-12
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 74 2e-12
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 74 2e-12
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 74 2e-12
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 74 2e-12
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 74 2e-12
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 74 2e-12
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 73 2e-12
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 73 2e-12
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 73 2e-12
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 73 3e-12
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 73 4e-12
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 73 4e-12
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 73 4e-12
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 73 4e-12
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 73 4e-12
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 72 5e-12
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 72 5e-12
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 72 6e-12
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 72 6e-12
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 72 6e-12
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 71 8e-12
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 71 8e-12
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 71 8e-12
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 71 8e-12
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 71 8e-12
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 71 1e-11
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 71 1e-11
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 71 1e-11
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 71 1e-11
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 71 1e-11
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 71 1e-11
Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen pr... 71 1e-11
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 71 1e-11
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 71 1e-11
BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotei... 71 1e-11
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 71 1e-11
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 71 1e-11
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 71 1e-11
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 71 1e-11
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 71 1e-11
AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotei... 71 1e-11
AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophobla... 71 1e-11
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 71 1e-11
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 71 1e-11
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 71 1e-11
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 71 1e-11
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 70 2e-11
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 70 2e-11
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 70 2e-11
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 70 3e-11
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 70 3e-11
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 70 3e-11
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 70 3e-11
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 69 3e-11
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 69 4e-11
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 69 4e-11
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 69 4e-11
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 69 4e-11
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 68 8e-11
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 68 8e-11
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 68 8e-11
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 68 8e-11
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 68 8e-11
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 68 8e-11
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 68 1e-10
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 68 1e-10
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 68 1e-10
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 68 1e-10
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 68 1e-10
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 68 1e-10
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 67 1e-10
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 67 2e-10
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 67 2e-10
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 67 2e-10
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 67 2e-10
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 67 2e-10
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 67 2e-10
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 67 2e-10
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 67 2e-10
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 67 2e-10
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 66 3e-10
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 66 3e-10
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 66 3e-10
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 66 3e-10
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 66 3e-10
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 66 4e-10
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 66 4e-10
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 66 4e-10
BC128608-1|AAI28609.1| 441|Homo sapiens reticulon 4 receptor-li... 65 5e-10
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 65 5e-10
AY250219-1|AAP82836.1| 441|Homo sapiens nogo receptor-like 2 pr... 65 5e-10
AF532859-1|AAP21836.1| 441|Homo sapiens Nogo-66 receptor homolo... 65 5e-10
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 65 7e-10
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 65 7e-10
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 64 2e-09
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 63 2e-09
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 63 2e-09
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 63 2e-09
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 63 2e-09
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 63 2e-09
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 63 2e-09
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 63 2e-09
DQ355157-1|ABC79623.1| 334|Homo sapiens cytokeratin associated ... 63 3e-09
BC110418-1|AAI10419.1| 504|Homo sapiens adhesion molecule with ... 63 3e-09
BC101365-1|AAI01366.1| 504|Homo sapiens adhesion molecule with ... 63 3e-09
BC101364-1|AAI01365.1| 504|Homo sapiens adhesion molecule with ... 63 3e-09
BC101363-1|AAI01364.1| 504|Homo sapiens adhesion molecule with ... 63 3e-09
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 63 3e-09
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 63 3e-09
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 63 3e-09
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 63 3e-09
AY358134-1|AAQ88501.1| 504|Homo sapiens TWLV6084 protein. 63 3e-09
AY237003-1|AAO48944.1| 504|Homo sapiens transmembrane protein A... 63 3e-09
AL929554-11|CAH72880.1| 334|Homo sapiens leucine rich repeat co... 63 3e-09
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 63 3e-09
AB058754-1|BAB47480.1| 523|Homo sapiens KIAA1851 protein protein. 63 3e-09
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 62 4e-09
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 4e-09
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 4e-09
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 4e-09
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 4e-09
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 62 4e-09
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 62 4e-09
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 62 4e-09
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 62 4e-09
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 62 4e-09
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 62 4e-09
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 62 4e-09
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 62 4e-09
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 62 4e-09
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 62 4e-09
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 62 4e-09
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 62 4e-09
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 62 4e-09
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 62 4e-09
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 62 4e-09
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 62 4e-09
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 5e-09
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 5e-09
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 5e-09
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 62 5e-09
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 62 5e-09
AK127591-1|BAC87047.1| 341|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 62 5e-09
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 62 7e-09
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 62 7e-09
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 62 7e-09
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 62 7e-09
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 62 7e-09
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 62 7e-09
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 62 7e-09
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 62 7e-09
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 62 7e-09
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 62 7e-09
BC132983-1|AAI32984.1| 313|Homo sapiens leucine rich repeat con... 61 9e-09
BC132981-1|AAI32982.1| 313|Homo sapiens leucine rich repeat con... 61 9e-09
AL157714-2|CAI15338.1| 313|Homo sapiens novel protein protein. 61 9e-09
AK098677-1|BAC05375.1| 313|Homo sapiens protein ( Homo sapiens ... 61 9e-09
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 61 1e-08
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 61 1e-08
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 61 1e-08
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 61 1e-08
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 61 1e-08
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 61 1e-08
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 61 1e-08
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 61 1e-08
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 61 1e-08
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 61 1e-08
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 60 2e-08
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 60 2e-08
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 60 2e-08
AK092954-1|BAC04007.1| 325|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 60 2e-08
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 60 3e-08
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 60 3e-08
BC101761-1|AAI01762.1| 545|Homo sapiens leucine-rich repeat LGI... 60 3e-08
BC101759-1|AAI01760.1| 545|Homo sapiens leucine-rich repeat LGI... 60 3e-08
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 60 3e-08
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 60 3e-08
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 60 3e-08
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 60 3e-08
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 60 3e-08
AJ487958-1|CAD32305.1| 545|Homo sapiens LGI1-like protein 2 pro... 60 3e-08
AJ487516-1|CAD31784.1| 545|Homo sapiens leucine-rich glioma ina... 60 3e-08
AF467955-1|AAM49553.1| 545|Homo sapiens LGI2 protein. 60 3e-08
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 60 3e-08
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 60 3e-08
AB067503-1|BAB67809.1| 542|Homo sapiens KIAA1916 protein protein. 60 3e-08
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 59 4e-08
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 59 4e-08
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 59 4e-08
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 59 4e-08
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 59 4e-08
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 59 4e-08
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 59 4e-08
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 59 4e-08
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 59 4e-08
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 59 4e-08
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 59 4e-08
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 59 5e-08
BC016048-1|AAH16048.1| 317|Homo sapiens LRRC38 protein protein. 59 5e-08
AL603749-2|CAH70436.1| 294|Homo sapiens leucine rich repeat con... 59 5e-08
AL354712-1|CAI21926.1| 294|Homo sapiens leucine rich repeat con... 59 5e-08
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 58 6e-08
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 58 6e-08
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 58 6e-08
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 58 6e-08
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 58 6e-08
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 58 6e-08
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 58 6e-08
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 58 6e-08
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 58 6e-08
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 58 6e-08
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 58 6e-08
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 58 8e-08
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 58 8e-08
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 58 8e-08
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 58 1e-07
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 58 1e-07
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 58 1e-07
M22403-1|AAA52596.1| 626|Homo sapiens platelet membrane glycopr... 57 1e-07
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 57 1e-07
J02940-1|AAA52595.1| 626|Homo sapiens GP1BA protein. 57 1e-07
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 57 1e-07
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 57 1e-07
BC027955-1|AAH27955.1| 626|Homo sapiens glycoprotein Ib (platel... 57 1e-07
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 57 1e-07
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 57 1e-07
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 57 1e-07
AM709890-1|CAM97225.1| 639|Homo sapiens platelet glycoprotein I... 57 1e-07
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 57 1e-07
AF395009-1|AAK71325.1| 626|Homo sapiens glycoprotein Ib (platel... 57 1e-07
AB086948-1|BAC10305.1| 626|Homo sapiens platelet glycoprotein I... 57 1e-07
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 57 2e-07
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 57 2e-07
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 57 2e-07
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 57 2e-07
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 57 2e-07
D83597-1|BAA12019.1| 661|Homo sapiens RP105 protein. 56 3e-07
BC109070-1|AAI09071.1| 661|Homo sapiens CD180 molecule protein. 56 3e-07
BC109069-1|AAI09070.1| 661|Homo sapiens CD180 molecule protein. 56 3e-07
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 56 3e-07
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 56 3e-07
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 56 3e-07
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 56 3e-07
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 56 3e-07
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 56 3e-07
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 56 3e-07
AB038516-1|BAB12038.1| 626|Homo sapiens platelet glycoprotein I... 56 4e-07
BC087848-1|AAH87848.1| 261|Homo sapiens LGI4 protein protein. 55 6e-07
BC043145-1|AAH43145.1| 1634|Homo sapiens leucine rich repeat con... 55 6e-07
BC040501-1|AAH40501.2| 1700|Homo sapiens leucine rich repeat con... 55 6e-07
AY358121-1|AAQ88488.1| 261|Homo sapiens LGI4 protein. 55 6e-07
AJ487959-1|CAD32306.1| 537|Homo sapiens LGI1-like protein 3 pro... 55 6e-07
AJ487519-1|CAD31787.1| 537|Homo sapiens leucine-rich glioma ina... 55 6e-07
AF467954-1|AAM49552.1| 537|Homo sapiens LGI4 protein. 55 6e-07
AB011135-1|BAA25489.3| 1652|Homo sapiens KIAA0563 protein protein. 55 6e-07
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 55 8e-07
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 55 8e-07
AJ314647-1|CAC44536.1| 946|Homo sapiens hypothetical protein pr... 54 1e-06
BC087849-1|AAH87849.1| 259|Homo sapiens LRRC3B protein protein. 54 1e-06
BC067784-1|AAH67784.1| 259|Homo sapiens leucine rich repeat con... 54 1e-06
BC040656-1|AAH40656.1| 259|Homo sapiens LRRC3B protein protein. 54 1e-06
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 54 1e-06
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 54 1e-06
AY358282-1|AAQ88649.1| 259|Homo sapiens NLVD195 protein. 54 1e-06
AF396933-1|AAK84157.1| 259|Homo sapiens LRP15 protein. 54 1e-06
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 53 2e-06
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 53 2e-06
AK128037-1|BAC87242.1| 1111|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 53 2e-06
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 53 3e-06
DQ864979-1|ABI23432.1| 193|Homo sapiens RTN4RL2 protein. 53 3e-06
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 53 3e-06
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 53 3e-06
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 53 3e-06
AY386261-1|AAR28082.1| 596|Homo sapiens c66 SLIT-like testicula... 53 3e-06
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 53 3e-06
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 53 3e-06
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF051152-1|AAC34377.1| 784|Homo sapiens Toll/interleukin-1 rece... 53 3e-06
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 53 3e-06
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 53 3e-06
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 53 3e-06
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 52 4e-06
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 52 7e-06
L43619-1|AAC41765.1| 4292|Homo sapiens polycystic kidney disease... 52 7e-06
L33243-1|AAC37576.1| 4302|Homo sapiens polycystic kidney disease... 52 7e-06
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 52 7e-06
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 52 7e-06
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 52 7e-06
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 52 7e-06
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 52 7e-06
BC022500-1|AAH22500.1| 557|Homo sapiens leucine-rich, glioma in... 52 7e-06
AY358885-1|AAQ89244.1| 557|Homo sapiens LGI1 protein. 52 7e-06
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 52 7e-06
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 52 7e-06
AL358154-2|CAI14982.1| 557|Homo sapiens leucine-rich, glioma in... 52 7e-06
AL358154-1|CAI14981.1| 291|Homo sapiens leucine-rich, glioma in... 52 7e-06
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 52 7e-06
AL157396-3|CAH73838.1| 557|Homo sapiens leucine-rich, glioma in... 52 7e-06
AL157396-2|CAH73837.1| 291|Homo sapiens leucine-rich, glioma in... 52 7e-06
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 52 7e-06
AF473548-1|AAM22074.1| 291|Homo sapiens leucine-rich glioma ina... 52 7e-06
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 52 7e-06
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 52 7e-06
AF055636-1|AAC99316.1| 557|Homo sapiens leucine-rich glioma-ina... 52 7e-06
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 52 7e-06
U24497-1|AAC50128.1| 4303|Homo sapiens autosomal dominant polycy... 51 9e-06
AY181242-1|AAO27354.1| 1331|Homo sapiens G protein-coupled recep... 51 9e-06
AY090637-1|AAM09084.1| 320|Homo sapiens tumor endothelial marke... 51 9e-06
AF378755-1|AAL11992.1| 1331|Homo sapiens tumor endothelial marke... 51 9e-06
AB040964-1|BAA96055.2| 1206|Homo sapiens KIAA1531 protein protein. 51 9e-06
CR533516-1|CAG38547.1| 298|Homo sapiens OGN protein. 51 1e-05
BT007296-1|AAP35960.1| 280|Homo sapiens protein phosphatase 1, ... 51 1e-05
BC095443-1|AAH95443.1| 298|Homo sapiens osteoglycin protein. 51 1e-05
BC037273-1|AAH37273.1| 298|Homo sapiens osteoglycin protein. 51 1e-05
BC013001-1|AAH13001.1| 280|Homo sapiens PPP1R7 protein protein. 51 1e-05
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 124 bits (299), Expect = 8e-28
Identities = 105/385 (27%), Positives = 169/385 (43%), Gaps = 24/385 (6%)
Query: 53 LTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ + Y L VLD+S N I ++ + F ++ LNL+ N + L+
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 112 AFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
AF G I+ + V+ F+ L L +LD + NR+ E TF+ L+SL++L
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVL 240
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
L+ N+I + + + L L N + +V+ L L L L L+NN I + +
Sbjct: 241 KLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXX 290
G+ L L LS NN+T + +L++LS+LS L LS
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 291 XXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALE 348
I+ S AF +L K+ + N K++ V R F G L ++ + NA+
Sbjct: 361 DLDHNEISGTIEDTSGAFSGLDSLSKLTLFGN-KIKSVAKRAFSGLEGLEHLNLGGNAIR 419
Query: 349 TLEASHF-PIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYE 405
+++ F + L+EL IS + F C+C L WL W +G+ + +
Sbjct: 420 SVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQA---------------FV 464
Query: 406 DVKCSGPLQLKGMLFVQIPESEFGC 430
C+ P LKG +P F C
Sbjct: 465 TATCAHPESLKGQSIFSVPPESFVC 489
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/224 (28%), Positives = 98/224 (43%), Gaps = 5/224 (2%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ N I L + AF L +LT LD++ N+I + F+ + + L L N + +L
Sbjct: 193 LRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLT 251
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF G + ++ + L+AL +L SNN + + + L
Sbjct: 252 DGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHE 311
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV- 228
L L N++ + +L + L L LS N I ++ L+ L+ LDL++N I
Sbjct: 312 LVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTI 371
Query: 229 -DQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
D G F L SL L L N + + A S L L HL L G
Sbjct: 372 EDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGG 415
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/196 (28%), Positives = 83/196 (42%), Gaps = 3/196 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L++SYNK+ ++ FE ++ + L+NN L + +I ++
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAV-PSLGAASSHVVSLFLQHNKIRSVE 131
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP-SANLGFVIHLE 192
+ +LE LD S N + F +K L+L N I + A G L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L LS+N I Q+ L L LDLN N I ++ L F L SL L L NN++ +
Sbjct: 192 TLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 253 PTSALSKLSNLSHLYL 268
A LS + L+L
Sbjct: 251 TDGAFWGLSKMHVLHL 266
Score = 52.4 bits (120), Expect = 4e-06
Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 5/235 (2%)
Query: 139 DLSALER-LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
DL + R L+ S N+L +P FE L +L+ + L NN + +PS H+ L L
Sbjct: 65 DLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAA-SSHVVSLFLQ 123
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
N I+ V L L+ LDL+ N I V F P ++ L+L+ N + + A
Sbjct: 124 HNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAF 183
Query: 258 SKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWM 317
LS S L L I+ F +L+ + +
Sbjct: 184 DGLSR-SLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKL 242
Query: 318 NDNVKVREVPPRLFHGNPKLTNIYMKNNAL-ETLEASHFPIDRLQELEISGNPFA 371
N + ++ F G K+ ++++ N+L E S + + L +L +S N A
Sbjct: 243 QRN-NISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIA 296
Score = 34.7 bits (76), Expect = 0.88
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 50 LMNLTHNAIDNLLY----AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+++L HN I + AF+ L+ L + NKI + F + HLNL N +
Sbjct: 359 VLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAI 418
Query: 106 KRLDKDAFV 114
+ + DAFV
Sbjct: 419 RSVQFDAFV 427
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 124 bits (299), Expect = 8e-28
Identities = 105/385 (27%), Positives = 169/385 (43%), Gaps = 24/385 (6%)
Query: 53 LTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ + Y L VLD+S N I ++ + F ++ LNL+ N + L+
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 112 AFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
AF G I+ + V+ F+ L L +LD + NR+ E TF+ L+SL++L
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVL 240
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
L+ N+I + + + L L N + +V+ L L L L L+NN I + +
Sbjct: 241 KLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXX 290
G+ L L LS NN+T + +L++LS+LS L LS
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 291 XXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALE 348
I+ S AF +L K+ + N K++ V R F G L ++ + NA+
Sbjct: 361 DLDHNEISGTIEDTSGAFSGLDSLSKLTLFGN-KIKSVAKRAFSGLEGLEHLNLGGNAIR 419
Query: 349 TLEASHF-PIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYE 405
+++ F + L+EL IS + F C+C L WL W +G+ + +
Sbjct: 420 SVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQA---------------FV 464
Query: 406 DVKCSGPLQLKGMLFVQIPESEFGC 430
C+ P LKG +P F C
Sbjct: 465 TATCAHPESLKGQSIFSVPPESFVC 489
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/224 (28%), Positives = 98/224 (43%), Gaps = 5/224 (2%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ N I L + AF L +LT LD++ N+I + F+ + + L L N + +L
Sbjct: 193 LRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLT 251
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF G + ++ + L+AL +L SNN + + + L
Sbjct: 252 DGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHE 311
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV- 228
L L N++ + +L + L L LS N I ++ L+ L+ LDL++N I
Sbjct: 312 LVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTI 371
Query: 229 -DQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
D G F L SL L L N + + A S L L HL L G
Sbjct: 372 EDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGG 415
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/196 (28%), Positives = 83/196 (42%), Gaps = 3/196 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L++SYNK+ ++ FE ++ + L+NN L + +I ++
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAV-PSLGAASSHVVSLFLQHNKIRSVE 131
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP-SANLGFVIHLE 192
+ +LE LD S N + F +K L+L N I + A G L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L LS+N I Q+ L L LDLN N I ++ L F L SL L L NN++ +
Sbjct: 192 TLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 253 PTSALSKLSNLSHLYL 268
A LS + L+L
Sbjct: 251 TDGAFWGLSKMHVLHL 266
Score = 52.4 bits (120), Expect = 4e-06
Identities = 58/235 (24%), Positives = 95/235 (40%), Gaps = 5/235 (2%)
Query: 139 DLSALER-LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
DL + R L+ S N+L +P FE L +L+ + L NN + +PS H+ L L
Sbjct: 65 DLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAA-SSHVVSLFLQ 123
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
N I+ V L L+ LDL+ N I V F P ++ L+L+ N + + A
Sbjct: 124 HNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAF 183
Query: 258 SKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWM 317
LS S L L I+ F +L+ + +
Sbjct: 184 DGLSR-SLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKL 242
Query: 318 NDNVKVREVPPRLFHGNPKLTNIYMKNNAL-ETLEASHFPIDRLQELEISGNPFA 371
N + ++ F G K+ ++++ N+L E S + + L +L +S N A
Sbjct: 243 QRN-NISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIA 296
Score = 34.7 bits (76), Expect = 0.88
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 50 LMNLTHNAIDNLLY----AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+++L HN I + AF+ L+ L + NKI + F + HLNL N +
Sbjct: 359 VLDLDHNEISGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAI 418
Query: 106 KRLDKDAFV 114
+ + DAFV
Sbjct: 419 RSVQFDAFV 427
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 111 bits (268), Expect = 5e-24
Identities = 92/358 (25%), Positives = 160/358 (44%), Gaps = 9/358 (2%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
TL++L HN I + A Y L LD+S N I ++ + +F ++++LNLSNN +
Sbjct: 123 TLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFP-RMQLKYLNLSNNRITT 181
Query: 108 LDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L+ F +S I + F+ L L+ L+ NR+ E TF+ L S
Sbjct: 182 LEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L+ L ++ N I + + ++E L+L N + +V++ L L+ L+ L ++ N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXX 286
+ + L LDLS N +T + SA LS L L L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 287 XXXXXXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
I+ S AF +L K+ + N +++ + + F G L ++ + N
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGN-QIKSITKKAFIGLESLEHLDLNN 419
Query: 345 NALETLEASHFPIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFL 400
NA+ +++ + F L+EL ++ + C+C L WL W + + + + S E+L
Sbjct: 420 NAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWL 477
Score = 89.4 bits (212), Expect = 3e-17
Identities = 90/368 (24%), Positives = 152/368 (41%), Gaps = 18/368 (4%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQ-----LNPEATLMNLTHNAIDNLLYAF 65
AA LCP C C L C+ L + L P+ +++ +HN + N +
Sbjct: 37 AAGAGLCPAPCSCRIPL--LDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISL 94
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
T L + ++YN++ ++ E S + L+L +N + ++ A
Sbjct: 95 ESQT-LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLS 152
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSAN 184
IS I +F + L+ L+ SNNR+ T E F+ L SSL ++ L N + IP
Sbjct: 153 SNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP-PK 210
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
+ + HL++L+L N I+ V L L+ L + N I + F L ++ L+L
Sbjct: 211 IFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELEL 270
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
NN+T + L L L LY+S R+D
Sbjct: 271 EHNNLTRVNKGWLYGLRMLQQLYVS-QNAIERISPDAWEFCQRLSELDLSYNQLTRLDES 329
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRL 360
AFV L+++ + DN +V + +F L + ++NN A+E + + L
Sbjct: 330 AFVGLSLLERLNLGDN-RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSL 388
Query: 361 QELEISGN 368
+L + GN
Sbjct: 389 TKLILQGN 396
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 111 bits (268), Expect = 5e-24
Identities = 92/358 (25%), Positives = 160/358 (44%), Gaps = 9/358 (2%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
TL++L HN I + A Y L LD+S N I ++ + +F ++++LNLSNN +
Sbjct: 123 TLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFP-RMQLKYLNLSNNRITT 181
Query: 108 LDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L+ F +S I + F+ L L+ L+ NR+ E TF+ L S
Sbjct: 182 LEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L+ L ++ N I + + ++E L+L N + +V++ L L+ L+ L ++ N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXX 286
+ + L LDLS N +T + SA LS L L L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 287 XXXXXXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
I+ S AF +L K+ + N +++ + + F G L ++ + N
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGN-QIKSITKKAFIGLESLEHLDLNN 419
Query: 345 NALETLEASHFPIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFL 400
NA+ +++ + F L+EL ++ + C+C L WL W + + + + S E+L
Sbjct: 420 NAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWL 477
Score = 89.4 bits (212), Expect = 3e-17
Identities = 90/368 (24%), Positives = 152/368 (41%), Gaps = 18/368 (4%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQ-----LNPEATLMNLTHNAIDNLLYAF 65
AA LCP C C L C+ L + L P+ +++ +HN + N +
Sbjct: 37 AAGAGLCPAPCSCRIPL--LDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISL 94
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
T L + ++YN++ ++ E S + L+L +N + ++ A
Sbjct: 95 ESQT-LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLS 152
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSAN 184
IS I +F + L+ L+ SNNR+ T E F+ L SSL ++ L N + IP
Sbjct: 153 SNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP-PK 210
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
+ + HL++L+L N I+ V L L+ L + N I + F L ++ L+L
Sbjct: 211 IFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELEL 270
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
NN+T + L L L LY+S R+D
Sbjct: 271 EHNNLTRVNKGWLYGLRMLQQLYVS-QNAIERISPDAWEFCQRLSELDLSYNQLTRLDES 329
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRL 360
AFV L+++ + DN +V + +F L + ++NN A+E + + L
Sbjct: 330 AFVGLSLLERLNLGDN-RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSL 388
Query: 361 QELEISGN 368
+L + GN
Sbjct: 389 TKLILQGN 396
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 111 bits (268), Expect = 5e-24
Identities = 92/358 (25%), Positives = 160/358 (44%), Gaps = 9/358 (2%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
TL++L HN I + A Y L LD+S N I ++ + +F ++++LNLSNN +
Sbjct: 123 TLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFP-RMQLKYLNLSNNRITT 181
Query: 108 LDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L+ F +S I + F+ L L+ L+ NR+ E TF+ L S
Sbjct: 182 LEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L+ L ++ N I + + ++E L+L N + +V++ L L+ L+ L ++ N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXX 286
+ + L LDLS N +T + SA LS L L L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 287 XXXXXXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
I+ S AF +L K+ + N +++ + + F G L ++ + N
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGN-QIKSITKKAFIGLESLEHLDLNN 419
Query: 345 NALETLEASHFPIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFL 400
NA+ +++ + F L+EL ++ + C+C L WL W + + + + S E+L
Sbjct: 420 NAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWL 477
Score = 89.4 bits (212), Expect = 3e-17
Identities = 90/368 (24%), Positives = 152/368 (41%), Gaps = 18/368 (4%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQ-----LNPEATLMNLTHNAIDNLLYAF 65
AA LCP C C L C+ L + L P+ +++ +HN + N +
Sbjct: 37 AAGAGLCPAPCSCRIPL--LDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISL 94
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
T L + ++YN++ ++ E S + L+L +N + ++ A
Sbjct: 95 ESQT-LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLS 152
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSAN 184
IS I +F + L+ L+ SNNR+ T E F+ L SSL ++ L N + IP
Sbjct: 153 SNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP-PK 210
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
+ + HL++L+L N I+ V L L+ L + N I + F L ++ L+L
Sbjct: 211 IFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELEL 270
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
NN+T + L L L LY+S R+D
Sbjct: 271 EHNNLTRVNKGWLYGLRMLQQLYVS-QNAIERISPDAWEFCQRLSELDLSYNQLTRLDES 329
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRL 360
AFV L+++ + DN +V + +F L + ++NN A+E + + L
Sbjct: 330 AFVGLSLLERLNLGDN-RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSL 388
Query: 361 QELEISGN 368
+L + GN
Sbjct: 389 TKLILQGN 396
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 111 bits (268), Expect = 5e-24
Identities = 92/358 (25%), Positives = 160/358 (44%), Gaps = 9/358 (2%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
TL++L HN I + A Y L LD+S N I ++ + +F ++++LNLSNN +
Sbjct: 131 TLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFP-RMQLKYLNLSNNRITT 189
Query: 108 LDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L+ F +S I + F+ L L+ L+ NR+ E TF+ L S
Sbjct: 190 LEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDS 248
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L+ L ++ N I + + ++E L+L N + +V++ L L+ L+ L ++ N IE
Sbjct: 249 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 308
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXX 286
+ + L LDLS N +T + SA LS L L L
Sbjct: 309 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 368
Query: 287 XXXXXXXXXXXXERID--SRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
I+ S AF +L K+ + N +++ + + F G L ++ + N
Sbjct: 369 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGN-QIKSITKKAFIGLESLEHLDLNN 427
Query: 345 NALETLEASHFPIDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFL 400
NA+ +++ + F L+EL ++ + C+C L WL W + + + + S E+L
Sbjct: 428 NAIMSIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWL 485
Score = 89.4 bits (212), Expect = 3e-17
Identities = 90/368 (24%), Positives = 152/368 (41%), Gaps = 18/368 (4%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQ-----LNPEATLMNLTHNAIDNLLYAF 65
AA LCP C C L C+ L + L P+ +++ +HN + N +
Sbjct: 45 AAGAGLCPAPCSCRIPL--LDCSRRKLPAPSWRALSGLLPPDTAILDFSHNRLSNWNISL 102
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
T L + ++YN++ ++ E S + L+L +N + ++ A
Sbjct: 103 ESQT-LQEVKMNYNELTEIPYFG-EPTSNITLLSLVHNIIPEINAQALQFYPALESLDLS 160
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSAN 184
IS I +F + L+ L+ SNNR+ T E F+ L SSL ++ L N + IP
Sbjct: 161 SNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP-PK 218
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
+ + HL++L+L N I+ V L L+ L + N I + F L ++ L+L
Sbjct: 219 IFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELEL 278
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
NN+T + L L L LY+S R+D
Sbjct: 279 EHNNLTRVNKGWLYGLRMLQQLYVS-QNAIERISPDAWEFCQRLSELDLSYNQLTRLDES 337
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRL 360
AFV L+++ + DN +V + +F L + ++NN A+E + + L
Sbjct: 338 AFVGLSLLERLNLGDN-RVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSL 396
Query: 361 QELEISGN 368
+L + GN
Sbjct: 397 TKLILQGN 404
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 107 bits (258), Expect = 8e-23
Identities = 99/396 (25%), Positives = 167/396 (42%), Gaps = 43/396 (10%)
Query: 2 VLFAWTWSAAAAKTL------CPVRCMCD--------DALRAASCANAN---LEIVPIQL 44
+L AW A AA + CP +C C + R A+ + N L VP L
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 45 NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
+ L N+I + + LT LD+S N D +F + ++ L+L N
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEEN 127
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
L RL+ +F G ++ I + F LS L RL ++N L + FE
Sbjct: 128 QLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEM 187
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L +L+IL + N + I N + +L L L+ ++++S + L L+ L+ L +N
Sbjct: 188 LPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ V + +P L+ LDL+ N + + + + +L L L+
Sbjct: 248 QLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS------- 300
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
ID A V+ L K+ + +N ++ + PR FH P++ + +
Sbjct: 301 -----------------IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLN 343
Query: 344 NNALETL-EASHFPIDRLQELEISGNPFACNCSLLW 378
NNAL L + + + LQE+ + GNP C+C + W
Sbjct: 344 NNALSALHQQTAESLPNLQEVGLHGNPIRCDCVIRW 379
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 107 bits (258), Expect = 8e-23
Identities = 99/396 (25%), Positives = 167/396 (42%), Gaps = 43/396 (10%)
Query: 2 VLFAWTWSAAAAKTL------CPVRCMCD--------DALRAASCANAN---LEIVPIQL 44
+L AW A AA + CP +C C + R A+ + N L VP L
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 45 NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
+ L N+I + + LT LD+S N D +F + ++ L+L N
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEEN 127
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
L RL+ +F G ++ I + F LS L RL ++N L + FE
Sbjct: 128 QLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEM 187
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L +L+IL + N + I N + +L L L+ ++++S + L L+ L+ L +N
Sbjct: 188 LPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ V + +P L+ LDL+ N + + + + +L L L+
Sbjct: 248 QLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS------- 300
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
ID A V+ L K+ + +N ++ + PR FH P++ + +
Sbjct: 301 -----------------IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLN 343
Query: 344 NNALETL-EASHFPIDRLQELEISGNPFACNCSLLW 378
NNAL L + + + LQE+ + GNP C+C + W
Sbjct: 344 NNALSALHQQTAESLPNLQEVGLHGNPIRCDCVIRW 379
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 5 protein.
Length = 713
Score = 107 bits (257), Expect = 1e-22
Identities = 99/396 (25%), Positives = 167/396 (42%), Gaps = 43/396 (10%)
Query: 2 VLFAWTWSAAAAKTL------CPVRCMCD--------DALRAASCANAN---LEIVPIQL 44
+L AW A AA + CP +C C + R A+ + N L VP L
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 45 NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
+ L N+I + + LT LD+S N D +F + ++ L+L N
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEEN 127
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
L RL+ +F G ++ I + F LS L RL ++N L + FE
Sbjct: 128 QLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEM 187
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L +L+IL + N + I N + +L L L+ ++++S + L L+ L+ L +N
Sbjct: 188 LPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ V + +P L+ LDL+ N + + + + +L L L+
Sbjct: 248 QLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS------- 300
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
ID A V+ L K+ + +N ++ + PR FH P++ + +
Sbjct: 301 -----------------IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLN 343
Query: 344 NNALETL-EASHFPIDRLQELEISGNPFACNCSLLW 378
NNAL L + + + LQE+ + GNP C+C + W
Sbjct: 344 NNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRW 379
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 107 bits (257), Expect = 1e-22
Identities = 99/396 (25%), Positives = 167/396 (42%), Gaps = 43/396 (10%)
Query: 2 VLFAWTWSAAAAKTL------CPVRCMCD--------DALRAASCANAN---LEIVPIQL 44
+L AW A AA + CP +C C + R A+ + N L VP L
Sbjct: 8 LLLAWVAGATAAVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 45 NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
+ L N+I + + LT LD+S N D +F + ++ L+L N
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEEN 127
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
L RL+ +F G ++ I + F LS L RL ++N L + FE
Sbjct: 128 QLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEM 187
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L +L+IL + N + I N + +L L L+ ++++S + L L+ L+ L +N
Sbjct: 188 LPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ V + +P L+ LDL+ N + + + + +L L L+
Sbjct: 248 QLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS------- 300
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
ID A V+ L K+ + +N ++ + PR FH P++ + +
Sbjct: 301 -----------------IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLN 343
Query: 344 NNALETL-EASHFPIDRLQELEISGNPFACNCSLLW 378
NNAL L + + + LQE+ + GNP C+C + W
Sbjct: 344 NNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRW 379
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 105 bits (253), Expect = 3e-22
Identities = 98/396 (24%), Positives = 166/396 (41%), Gaps = 43/396 (10%)
Query: 2 VLFAWTWSAAAAKTL------CPVRCMCD--------DALRAASCANAN---LEIVPIQL 44
+L AW A A + CP +C C + R A+ + N L VP L
Sbjct: 8 LLLAWVAGATATVPVVPWHVPCPPQCACQIRPWYTPRSSYREATTVDCNDLFLTAVPPAL 67
Query: 45 NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
+ L N+I + + LT LD+S N D +F + ++ L+L N
Sbjct: 68 PAGTQTLLLQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEEN 127
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
L RL+ +F G ++ I + F LS L RL ++N L + FE
Sbjct: 128 QLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEM 187
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L +L+IL + N + I N + +L L L+ ++++S + L L+ L+ L +N
Sbjct: 188 LPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDN 247
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ V + +P L+ LDL+ N + + + + +L L L+
Sbjct: 248 QLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVS------- 300
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
ID A V+ L K+ + +N ++ + PR FH P++ + +
Sbjct: 301 -----------------IDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLN 343
Query: 344 NNALETL-EASHFPIDRLQELEISGNPFACNCSLLW 378
NNAL L + + + LQE+ + GNP C+C + W
Sbjct: 344 NNALSALHQQTVESLPNLQEVGLHGNPIRCDCVIRW 379
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 103 bits (246), Expect = 2e-21
Identities = 71/244 (29%), Positives = 113/244 (46%), Gaps = 3/244 (1%)
Query: 28 RAASCANANLEIVPIQLNPEATLMNLTHNAID--NLLYAFNLYTQLTVLDISYNKILDLG 85
R +C N L +P + LT N I N L++ L L + + IL +
Sbjct: 42 RQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHS-LVALYLDNSNILYVY 100
Query: 86 SENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALER 145
+ F + L L+NNF+KRLD F G ++S + F DL +++
Sbjct: 101 PKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQY 160
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ NRL TF + +L+IL L NN+IL I + + +L L L N + +V
Sbjct: 161 LNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
+ LK L+ L L++N IE++ F L +L +L L ++ + + S ++NL H
Sbjct: 221 SNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKH 280
Query: 266 LYLS 269
L LS
Sbjct: 281 LILS 284
Score = 95.1 bits (226), Expect = 6e-19
Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 1/203 (0%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
FN + L++ N++ LGS F +R L+LSNN + R+ + F
Sbjct: 152 FNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYL 211
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ + F L +L RL S+N + +P F+ L++L+ L L+N+ I ++
Sbjct: 212 GSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDG 271
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLD 243
+ +L++L LS N ++ ++ LK L +L L+ N I S+D F ++ SL+ L+
Sbjct: 272 FSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILN 331
Query: 244 LSDNNMTLIPTSALSKLSNLSHL 266
LS NN+T + L LS+L HL
Sbjct: 332 LSFNNLTALHPRVLKPLSSLIHL 354
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/197 (29%), Positives = 88/197 (44%), Gaps = 1/197 (0%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN++ + F +++LNL N L L FVG I I
Sbjct: 137 LYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRIS 196
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ L L L +N L FE L SL+ LSL +N I I + +LEY
Sbjct: 197 ESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEY 256
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L + I+ V+R G + LKHL L++N +E+++ F L +L +L L N + I
Sbjct: 257 LLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISID 316
Query: 254 TSALSKL-SNLSHLYLS 269
+ ++L L LS
Sbjct: 317 NDTFENMGASLKILNLS 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF + L L +S+N I + F+ + + +L L N+ ++ + +D F G
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPS 182
++ N++ TF L L L NR+++ + +TFE + +SLKIL+L N++ +
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 183 ANLGFVIHLEYLDLSEN 199
L + L +L + N
Sbjct: 343 RVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L+HN I+ + +AF L L + ++I ++ + F + ++HL LS+N L+ L+
Sbjct: 233 LSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLN 292
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA-LERLDFSNNRLVTFEPETFEPLSSLK 168
D F I +I TF ++ A L+ L+ S N L P +PLSSL
Sbjct: 293 SDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLI 352
Query: 169 ILSLRNN 175
L +N
Sbjct: 353 HLQANSN 359
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 103 bits (246), Expect = 2e-21
Identities = 71/244 (29%), Positives = 113/244 (46%), Gaps = 3/244 (1%)
Query: 28 RAASCANANLEIVPIQLNPEATLMNLTHNAID--NLLYAFNLYTQLTVLDISYNKILDLG 85
R +C N L +P + LT N I N L++ L L + + IL +
Sbjct: 42 RQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHS-LVALYLDNSNILYVY 100
Query: 86 SENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALER 145
+ F + L L+NNF+KRLD F G ++S + F DL +++
Sbjct: 101 PKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQY 160
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ NRL TF + +L+IL L NN+IL I + + +L L L N + +V
Sbjct: 161 LNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
+ LK L+ L L++N IE++ F L +L +L L ++ + + S ++NL H
Sbjct: 221 SNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKH 280
Query: 266 LYLS 269
L LS
Sbjct: 281 LILS 284
Score = 95.1 bits (226), Expect = 6e-19
Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 1/203 (0%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
FN + L++ N++ LGS F +R L+LSNN + R+ + F
Sbjct: 152 FNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYL 211
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ + F L +L RL S+N + +P F+ L++L+ L L+N+ I ++
Sbjct: 212 GSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDG 271
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLD 243
+ +L++L LS N ++ ++ LK L +L L+ N I S+D F ++ SL+ L+
Sbjct: 272 FSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILN 331
Query: 244 LSDNNMTLIPTSALSKLSNLSHL 266
LS NN+T + L LS+L HL
Sbjct: 332 LSFNNLTALHPRVLKPLSSLIHL 354
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/197 (29%), Positives = 88/197 (44%), Gaps = 1/197 (0%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN++ + F +++LNL N L L FVG I I
Sbjct: 137 LYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRIS 196
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ L L L +N L FE L SL+ LSL +N I I + +LEY
Sbjct: 197 ESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEY 256
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L + I+ V+R G + LKHL L++N +E+++ F L +L +L L N + I
Sbjct: 257 LLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISID 316
Query: 254 TSALSKL-SNLSHLYLS 269
+ ++L L LS
Sbjct: 317 NDTFENMGASLKILNLS 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF + L L +S+N I + F+ + + +L L N+ ++ + +D F G
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPS 182
++ N++ TF L L L NR+++ + +TFE + +SLKIL+L N++ +
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 183 ANLGFVIHLEYLDLSEN 199
L + L +L + N
Sbjct: 343 RVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L+HN I+ + +AF L L + ++I ++ + F + ++HL LS+N L+ L+
Sbjct: 233 LSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLN 292
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA-LERLDFSNNRLVTFEPETFEPLSSLK 168
D F I +I TF ++ A L+ L+ S N L P +PLSSL
Sbjct: 293 SDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLI 352
Query: 169 ILSLRNN 175
L +N
Sbjct: 353 HLQANSN 359
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 103 bits (246), Expect = 2e-21
Identities = 71/244 (29%), Positives = 113/244 (46%), Gaps = 3/244 (1%)
Query: 28 RAASCANANLEIVPIQLNPEATLMNLTHNAID--NLLYAFNLYTQLTVLDISYNKILDLG 85
R +C N L +P + LT N I N L++ L L + + IL +
Sbjct: 42 RQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHS-LVALYLDNSNILYVY 100
Query: 86 SENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALER 145
+ F + L L+NNF+KRLD F G ++S + F DL +++
Sbjct: 101 PKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQY 160
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ NRL TF + +L+IL L NN+IL I + + +L L L N + +V
Sbjct: 161 LNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVP 220
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
+ LK L+ L L++N IE++ F L +L +L L ++ + + S ++NL H
Sbjct: 221 SNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKH 280
Query: 266 LYLS 269
L LS
Sbjct: 281 LILS 284
Score = 95.1 bits (226), Expect = 6e-19
Identities = 60/203 (29%), Positives = 103/203 (50%), Gaps = 1/203 (0%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
FN + L++ N++ LGS F +R L+LSNN + R+ + F
Sbjct: 152 FNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYL 211
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ + F L +L RL S+N + +P F+ L++L+ L L+N+ I ++
Sbjct: 212 GSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDG 271
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLD 243
+ +L++L LS N ++ ++ LK L +L L+ N I S+D F ++ SL+ L+
Sbjct: 272 FSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILN 331
Query: 244 LSDNNMTLIPTSALSKLSNLSHL 266
LS NN+T + L LS+L HL
Sbjct: 332 LSFNNLTALHPRVLKPLSSLIHL 354
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/197 (29%), Positives = 88/197 (44%), Gaps = 1/197 (0%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN++ + F +++LNL N L L FVG I I
Sbjct: 137 LYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRIS 196
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ L L L +N L FE L SL+ LSL +N I I + +LEY
Sbjct: 197 ESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEY 256
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L + I+ V+R G + LKHL L++N +E+++ F L +L +L L N + I
Sbjct: 257 LLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISID 316
Query: 254 TSALSKL-SNLSHLYLS 269
+ ++L L LS
Sbjct: 317 NDTFENMGASLKILNLS 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF + L L +S+N I + F+ + + +L L N+ ++ + +D F G
Sbjct: 223 AFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLI 282
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPS 182
++ N++ TF L L L NR+++ + +TFE + +SLKIL+L N++ +
Sbjct: 283 LSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHP 342
Query: 183 ANLGFVIHLEYLDLSEN 199
L + L +L + N
Sbjct: 343 RVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 37/127 (29%), Positives = 62/127 (48%), Gaps = 2/127 (1%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L+HN I+ + +AF L L + ++I ++ + F + ++HL LS+N L+ L+
Sbjct: 233 LSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLN 292
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA-LERLDFSNNRLVTFEPETFEPLSSLK 168
D F I +I TF ++ A L+ L+ S N L P +PLSSL
Sbjct: 293 SDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLI 352
Query: 169 ILSLRNN 175
L +N
Sbjct: 353 HLQANSN 359
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 102 bits (244), Expect = 4e-21
Identities = 80/309 (25%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
+LD+S N++ + E F S + ++LS+N + ++ AF + +
Sbjct: 61 ILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLV 120
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F LS L +LD S N++V F+ L +LK L + +N ++ I ++ LE
Sbjct: 121 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLE 180
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTL 251
L L + + V L L+ L L L + I ++ F L L+HL++ + +
Sbjct: 181 QLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDM 240
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+P ++L L NL+ L ++ I++ F D I
Sbjct: 241 MPANSLYGL-NLTSLSVTN-TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ++ + ++R + P F G L + + N LETLE + F R L+ L I+ NP
Sbjct: 299 LQELHI-VGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Query: 371 ACNCSLLWL 379
AC+C LLW+
Sbjct: 358 ACDCRLLWI 366
Score = 85.8 bits (203), Expect = 4e-16
Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLD 75
CP RC C ++ SC L +P + E +++L+ N + ++ F Y L +D
Sbjct: 28 CPARCECSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEID 87
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I ++ F + +R L L N LK + F G +I +
Sbjct: 88 LSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDY 147
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
F+DL L+ L+ +N LV F L SL+ L+L ++ +P+ L + L L
Sbjct: 148 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 207
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
L I + + L LKHL+++ +++ + + L +L L +++ N++ +P
Sbjct: 208 LKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPF 266
Query: 255 SALSKLSNLSHLYLS 269
A L L+HL LS
Sbjct: 267 LAFKHLVYLTHLNLS 281
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 4/178 (2%)
Query: 26 ALRAASCANANLEIVPIQ-LNPEATL--MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKI 81
+L + NL VP + L+ +L ++L H I+N+ +YAF L L+I Y +
Sbjct: 178 SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL 237
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
LD+ N + L+++N L + AF IS I F DL
Sbjct: 238 LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLI 297
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L +L T EP +F+ L L++L++ N + + LE L ++ N
Sbjct: 298 RLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 52.8 bits (121), Expect = 3e-06
Identities = 50/208 (24%), Positives = 85/208 (40%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
++ + + L +L L + + F+ L LK L + +LD+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
AN + ++L L ++ + V L L HL+L+ N I +++ F L L+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L + + I + L L L +S
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVS 329
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L+V + + + + L F+ + HLNLS N + ++ F
Sbjct: 244 NSLYGLNL-TSLSVTNTNLSTVPFLA---FKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
++ I +F+ L L L+ S N L T E F +L++LS+ NN +
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P E K LDL+ N ++SV+ F S P L +DLSDN + + A + L NL L
Sbjct: 54 GIPI--ETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLR 111
Query: 268 LSG 270
L G
Sbjct: 112 LKG 114
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 102 bits (244), Expect = 4e-21
Identities = 80/309 (25%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
+LD+S N++ + E F S + ++LS+N + ++ AF + +
Sbjct: 61 ILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLV 120
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F LS L +LD S N++V F+ L +LK L + +N ++ I ++ LE
Sbjct: 121 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLE 180
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTL 251
L L + + V L L+ L L L + I ++ F L L+HL++ + +
Sbjct: 181 QLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDM 240
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+P ++L L NL+ L ++ I++ F D I
Sbjct: 241 MPANSLYGL-NLTSLSVTN-TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ++ + ++R + P F G L + + N LETLE + F R L+ L I+ NP
Sbjct: 299 LQELHI-VGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Query: 371 ACNCSLLWL 379
AC+C LLW+
Sbjct: 358 ACDCRLLWI 366
Score = 85.8 bits (203), Expect = 4e-16
Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLD 75
CP RC C ++ SC L +P + E +++L+ N + ++ F Y L +D
Sbjct: 28 CPARCECSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEID 87
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I ++ F + +R L L N LK + F G +I +
Sbjct: 88 LSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDY 147
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
F+DL L+ L+ +N LV F L SL+ L+L ++ +P+ L + L L
Sbjct: 148 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 207
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
L I + + L LKHL+++ +++ + + L +L L +++ N++ +P
Sbjct: 208 LKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPF 266
Query: 255 SALSKLSNLSHLYLS 269
A L L+HL LS
Sbjct: 267 LAFKHLVYLTHLNLS 281
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 4/178 (2%)
Query: 26 ALRAASCANANLEIVPIQ-LNPEATL--MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKI 81
+L + NL VP + L+ +L ++L H I+N+ +YAF L L+I Y +
Sbjct: 178 SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL 237
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
LD+ N + L+++N L + AF IS I F DL
Sbjct: 238 LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLI 297
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L +L T EP +F+ L L++L++ N + + LE L ++ N
Sbjct: 298 RLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 52.8 bits (121), Expect = 3e-06
Identities = 50/208 (24%), Positives = 85/208 (40%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
++ + + L +L L + + F+ L LK L + +LD+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
AN + ++L L ++ + V L L HL+L+ N I +++ F L L+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L + + I + L L L +S
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVS 329
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L+V + + + + L F+ + HLNLS N + ++ F
Sbjct: 244 NSLYGLNL-TSLSVTNTNLSTVPFLA---FKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
++ I +F+ L L L+ S N L T E F +L++LS+ NN +
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P E K LDL+ N ++SV+ F S P L +DLSDN + + A + L NL L
Sbjct: 54 GIPI--ETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLR 111
Query: 268 LSG 270
L G
Sbjct: 112 LKG 114
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 102 bits (244), Expect = 4e-21
Identities = 80/309 (25%), Positives = 138/309 (44%), Gaps = 5/309 (1%)
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
+LD+S N++ + E F S + ++LS+N + ++ AF + +
Sbjct: 61 ILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLV 120
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F LS L +LD S N++V F+ L +LK L + +N ++ I ++ LE
Sbjct: 121 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLE 180
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTL 251
L L + + V L L+ L L L + I ++ F L L+HL++ + +
Sbjct: 181 QLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDM 240
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+P ++L L NL+ L ++ I++ F D I
Sbjct: 241 MPANSLYGL-NLTSLSVTN-TNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ++ + ++R + P F G L + + N LETLE + F R L+ L I+ NP
Sbjct: 299 LQELHI-VGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Query: 371 ACNCSLLWL 379
AC+C LLW+
Sbjct: 358 ACDCRLLWI 366
Score = 85.8 bits (203), Expect = 4e-16
Identities = 66/255 (25%), Positives = 115/255 (45%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLD 75
CP RC C ++ SC L +P + E +++L+ N + ++ F Y L +D
Sbjct: 28 CPARCECSAQNKSVSCHRRRLIAIPEGIPIETKILDLSKNRLKSVNPEEFISYPLLEEID 87
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I ++ F + +R L L N LK + F G +I +
Sbjct: 88 LSDNIIANVEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDY 147
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
F+DL L+ L+ +N LV F L SL+ L+L ++ +P+ L + L L
Sbjct: 148 MFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLH 207
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
L I + + L LKHL+++ +++ + + L +L L +++ N++ +P
Sbjct: 208 LKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPF 266
Query: 255 SALSKLSNLSHLYLS 269
A L L+HL LS
Sbjct: 267 LAFKHLVYLTHLNLS 281
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 4/178 (2%)
Query: 26 ALRAASCANANLEIVPIQ-LNPEATL--MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKI 81
+L + NL VP + L+ +L ++L H I+N+ +YAF L L+I Y +
Sbjct: 178 SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL 237
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
LD+ N + L+++N L + AF IS I F DL
Sbjct: 238 LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLI 297
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L +L T EP +F+ L L++L++ N + + LE L ++ N
Sbjct: 298 RLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 355
Score = 52.8 bits (121), Expect = 3e-06
Identities = 50/208 (24%), Positives = 85/208 (40%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 122 LGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQ 181
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
++ + + L +L L + + F+ L LK L + +LD+
Sbjct: 182 LTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMM 241
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
AN + ++L L ++ + V L L HL+L+ N I +++ F L L+
Sbjct: 242 PANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQE 301
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L + + I + L L L +S
Sbjct: 302 LHIVGAQLRTIEPHSFQGLRFLRVLNVS 329
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L+V + + + + L F+ + HLNLS N + ++ F
Sbjct: 244 NSLYGLNL-TSLSVTNTNLSTVPFLA---FKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 299
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
++ I +F+ L L L+ S N L T E F +L++LS+ NN +
Sbjct: 300 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 357
Score = 43.6 bits (98), Expect = 0.002
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P E K LDL+ N ++SV+ F S P L +DLSDN + + A + L NL L
Sbjct: 54 GIPI--ETKILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLR 111
Query: 268 LSG 270
L G
Sbjct: 112 LKG 114
>DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice
variant 3 protein.
Length = 640
Score = 99 bits (238), Expect = 2e-20
Identities = 71/254 (27%), Positives = 119/254 (46%), Gaps = 4/254 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C NL VP ++ L+NL N I + + +F L +L
Sbjct: 47 CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I + F + + L L +N L + AFV I +I
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTISNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 136 TFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
F + +L RLD + +++ E FE LS+L+ L+L ++ +IP NL +I L+ L
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP--NLTPLIKLDEL 224
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
DLS N + + L L+ L + + I+ +++ F +L SL ++L+ NN+TL+P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 255 SALSKLSNLSHLYL 268
+ L +L ++L
Sbjct: 285 DLFTPLHHLERIHL 298
Score = 96.3 bits (229), Expect = 3e-19
Identities = 75/295 (25%), Positives = 129/295 (43%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N++ + +F+ L L+IL L N I I + +L L+L +N + +S
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIS 140
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +LK L L NN IES+ F+ +PSLR LDL + ++ I A LSNL
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L+ I +F ++LQK+WM + +++
Sbjct: 201 YLNLA---MCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS-QIQ 256
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L I + +N L L F P+ L+ + + NP++CNC +LWL W +
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWSCNCDILWLSWWI 316
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C+ P LKG ++ ++ F C + +++
Sbjct: 317 KDMAPSNTACC-------------ARCNTPPNLKGRYIGELDQNYFTCYAPVIVE 358
>BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein.
Length = 640
Score = 99.5 bits (237), Expect = 3e-20
Identities = 71/254 (27%), Positives = 119/254 (46%), Gaps = 4/254 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C NL VP ++ L+NL N I + + +F L +L
Sbjct: 47 CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I + F + + L L +N L + AFV I +I
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 136 TFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
F + +L RLD + +++ E FE LS+L+ L+L ++ +IP NL +I L+ L
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP--NLTPLIKLDEL 224
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
DLS N + + L L+ L + + I+ +++ F +L SL ++L+ NN+TL+P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 255 SALSKLSNLSHLYL 268
+ L +L ++L
Sbjct: 285 DLFTPLHHLERIHL 298
Score = 93.1 bits (221), Expect = 2e-18
Identities = 74/295 (25%), Positives = 127/295 (43%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N++ + +F+ L L+IL L N I I + +L L+L +N + +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +LK L L NN IES+ F+ +PSLR LDL + ++ I A LSNL
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L+ I +F ++LQK+WM + +++
Sbjct: 201 YLNLA---MCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS-QIQ 256
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L I + +N L L F P+ L+ + + NP+ CNC +LWL W +
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWI 316
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C+ P LKG ++ ++ F C + +++
Sbjct: 317 KDMAPSNTACC-------------ARCNTPPNLKGRYIGELDQNYFTCYAPVIVE 358
>AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein.
Length = 640
Score = 99.5 bits (237), Expect = 3e-20
Identities = 71/254 (27%), Positives = 119/254 (46%), Gaps = 4/254 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C NL VP ++ L+NL N I + + +F L +L
Sbjct: 47 CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I + F + + L L +N L + AFV I +I
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 136 TFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
F + +L RLD + +++ E FE LS+L+ L+L ++ +IP NL +I L+ L
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP--NLTPLIKLDEL 224
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
DLS N + + L L+ L + + I+ +++ F +L SL ++L+ NN+TL+P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 255 SALSKLSNLSHLYL 268
+ L +L ++L
Sbjct: 285 DLFTPLHHLERIHL 298
Score = 93.1 bits (221), Expect = 2e-18
Identities = 74/295 (25%), Positives = 127/295 (43%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N++ + +F+ L L+IL L N I I + +L L+L +N + +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +LK L L NN IES+ F+ +PSLR LDL + ++ I A LSNL
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L+ I +F ++LQK+WM + +++
Sbjct: 201 YLNLA---MCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS-QIQ 256
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L I + +N L L F P+ L+ + + NP+ CNC +LWL W +
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWI 316
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C+ P LKG ++ ++ F C + +++
Sbjct: 317 KDMAPSNTACC-------------ARCNTPPNLKGRYIGELDQNYFTCYAPVIVE 358
>AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein.
Length = 640
Score = 99.5 bits (237), Expect = 3e-20
Identities = 71/254 (27%), Positives = 119/254 (46%), Gaps = 4/254 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C NL VP ++ L+NL N I + + +F L +L
Sbjct: 47 CPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I + F + + L L +N L + AFV I +I
Sbjct: 107 LSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 136 TFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
F + +L RLD + +++ E FE LS+L+ L+L ++ +IP NL +I L+ L
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP--NLTPLIKLDEL 224
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
DLS N + + L L+ L + + I+ +++ F +L SL ++L+ NN+TL+P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 255 SALSKLSNLSHLYL 268
+ L +L ++L
Sbjct: 285 DLFTPLHHLERIHL 298
Score = 93.1 bits (221), Expect = 2e-18
Identities = 74/295 (25%), Positives = 127/295 (43%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N++ + +F+ L L+IL L N I I + +L L+L +N + +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIP 140
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +LK L L NN IES+ F+ +PSLR LDL + ++ I A LSNL
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L+ I +F ++LQK+WM + +++
Sbjct: 201 YLNLA---MCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS-QIQ 256
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L I + +N L L F P+ L+ + + NP+ CNC +LWL W +
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWI 316
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C+ P LKG ++ ++ F C + +++
Sbjct: 317 KDMAPSNTACC-------------ARCNTPPNLKGRYIGELDQNYFTCYAPVIVE 358
>BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/296 (26%), Positives = 127/296 (42%), Gaps = 20/296 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L I +F +L+K+W+ N +V
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVM-NSQVS 255
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F G L + + +N L +L F P+ L EL + NP+ C+C +LWL W L
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWL 315
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
+ T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 316 REYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 358
Score = 85.8 bits (203), Expect = 4e-16
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 4/262 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
++ LE L++S N ++ L LK L + N+ + +++ F L SL L+L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ +P + L L L+L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat
containing 4 protein.
Length = 653
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/296 (26%), Positives = 127/296 (42%), Gaps = 20/296 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L I +F +L+K+W+ N +V
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVM-NSQVS 255
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F G L + + +N L +L F P+ L EL + NP+ C+C +LWL W L
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWL 315
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
+ T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 316 REYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 358
Score = 85.8 bits (203), Expect = 4e-16
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 4/262 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
++ LE L++S N ++ L LK L + N+ + +++ F L SL L+L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ +P + L L L+L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein.
Length = 653
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/296 (26%), Positives = 127/296 (42%), Gaps = 20/296 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L I +F +L+K+W+ N +V
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVM-NSQVS 255
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F G L + + +N L +L F P+ L EL + NP+ C+C +LWL W L
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWL 315
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
+ T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 316 REYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 358
Score = 85.8 bits (203), Expect = 4e-16
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 4/262 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
++ LE L++S N ++ L LK L + N+ + +++ F L SL L+L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ +P + L L L+L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated
protein LRRC4 protein.
Length = 653
Score = 98.7 bits (235), Expect = 5e-20
Identities = 77/296 (26%), Positives = 127/296 (42%), Gaps = 20/296 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L I +F +L+K+W+ N +V
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVM-NSQVS 255
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F G L + + +N L +L F P+ L EL + NP+ C+C +LWL W L
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWL 315
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
+ T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 316 REYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 358
Score = 85.8 bits (203), Expect = 4e-16
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 4/262 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
++ LE L++S N ++ L LK L + N+ + +++ F L SL L+L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ +P + L L L+L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 246 QGLTWTWSSLHNLDLSG 262
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 92 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 151
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 152 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 270
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 271 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 133 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 192
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 193 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 252
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 253 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
Query: 225 IE 226
E
Sbjct: 313 WE 314
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 246 QGLTWTWSSLHNLDLSG 262
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 92 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 151
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 152 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 270
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 271 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 133 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 192
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 193 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 252
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 253 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
Query: 225 IE 226
E
Sbjct: 313 WE 314
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 247 QGLTWTWSSLHNLDLSG 263
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 93 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 152
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 153 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 212
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 213 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 271
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 272 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 134 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 193
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 194 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 253
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 254 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 313
Query: 225 IE 226
E
Sbjct: 314 WE 315
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 127 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 186
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 187 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 246
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 247 QGLTWTWSSLHNLDLSG 263
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 93 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 152
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 153 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 212
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 213 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 271
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 272 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 311
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 134 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 193
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 194 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 253
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 254 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 313
Query: 225 IE 226
E
Sbjct: 314 WE 315
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 246 QGLTWTWSSLHNLDLSG 262
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 92 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 151
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 152 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 270
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 271 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 133 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 192
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 193 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 252
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 253 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
Query: 225 IE 226
E
Sbjct: 313 WE 314
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 246 QGLTWTWSSLHNLDLSG 262
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 92 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 151
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 152 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 270
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 271 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 133 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 192
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 193 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 252
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 253 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
Query: 225 IE 226
E
Sbjct: 313 WE 314
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 98.3 bits (234), Expect = 6e-20
Identities = 62/197 (31%), Positives = 99/197 (50%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I L S F +++ L L +N++ +D+DAF G +I+ +H
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+TF + L LD S N+L T + E F+ L L IL LR+NS+ +P +L++
Sbjct: 126 NKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N ++ +SR+ L +LK L L +N ++ F L +LR + L N + I
Sbjct: 186 LDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSIS 245
Query: 254 TSALSKLSNLSHLYLSG 270
S+L +L LSG
Sbjct: 246 QGLTWTWSSLHNLDLSG 262
Score = 88.2 bits (209), Expect = 7e-17
Identities = 66/220 (30%), Positives = 106/220 (48%), Gaps = 3/220 (1%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF +L L +S NKI L ++ F +R+L+LS N L+ L +
Sbjct: 92 LDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSE 151
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + ++ F+D L+ LD NRL + F L LK L
Sbjct: 152 QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELH 211
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNIIESVDQ 230
L +N I A+ + +L + L N I+ +S+ GL + L +LDL+ N I+ ++
Sbjct: 212 LEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQ-GLTWTWSSLHNLDLSGNDIQGIEP 270
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
F LP+L+ L+L N +T I ++ +L + LSG
Sbjct: 271 GTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSG 310
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/182 (22%), Positives = 73/182 (40%), Gaps = 1/182 (0%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P ++L++N + L F +L +L + N + + F+ + L+L N
Sbjct: 133 PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNR 192
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ L ++AF G + S I+ F L L + NR+ +
Sbjct: 193 LRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTW 252
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SSL L L N I I + +L+ L+L N + +S+ + L + L+ N+
Sbjct: 253 SSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGNM 312
Query: 225 IE 226
E
Sbjct: 313 WE 314
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 97.9 bits (233), Expect = 8e-20
Identities = 88/330 (26%), Positives = 144/330 (43%), Gaps = 6/330 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L +N + L + F L L +S N++L + +F S ++ L L N L+ +
Sbjct: 106 LSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP 165
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF +++I + F+ L L+ L NRL TF+ L +L+
Sbjct: 166 DGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 225
Query: 170 LSLRNNSILDIPSANLGFVIH-LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L+L+ N I + S L H L+ L LS N I Q+ L +L L L N ++ +
Sbjct: 226 LALQQNQI-GLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKEL 284
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXX 288
F +P+LR L L DN+++ +P + S L L L LS
Sbjct: 285 SPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILS-RNQISFISPGAFNGLTEL 343
Query: 289 XXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALE 348
+ +D F NLQ I + +N ++R++P +F L I ++NN LE
Sbjct: 344 RELSLHTNALQDLDGNVFRMLANLQNISLQNN-RLRQLPGNIFANVNGLMAIQLQNNQLE 402
Query: 349 TLEASHFP-IDRLQELEISGNPFACNCSLL 377
L F + +L EL + NP+ C+ +L
Sbjct: 403 NLPLGIFDHLGKLCELRLYDNPWRCDSDIL 432
Score = 91.5 bits (217), Expect = 7e-18
Identities = 88/363 (24%), Positives = 145/363 (39%), Gaps = 5/363 (1%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FN 66
W A A CP C C A + C A + VP L A + + + I L + F
Sbjct: 16 WGAGLAYHGCPSECTCSRASQV-ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFL 74
Query: 67 LYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXX 126
+ L L I N++ + F + +R+L+L+NN L+ L F G
Sbjct: 75 NISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSS 134
Query: 127 XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F S L+ L N L F+ L L L+L NS+ I
Sbjct: 135 NQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQ 194
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ +L+ L L EN + + L L+ L L N I + FH+ +L+ L LS+
Sbjct: 195 HLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSN 254
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
N+++ +P S +L L+ L L G D+ F
Sbjct: 255 NHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDN-VF 313
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEI 365
+ LQ + ++ N ++ + P F+G +L + + NAL+ L+ + F + LQ + +
Sbjct: 314 SNLRQLQVLILSRN-QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISL 372
Query: 366 SGN 368
N
Sbjct: 373 QNN 375
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 4/147 (2%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P+ + L N++ L F L L + N I L F + +++ L LS N
Sbjct: 269 PQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQ 328
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
+ + AF G + ++ FR L+ L+ + NNRL F +
Sbjct: 329 ISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANV 388
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHL 191
+ L + L+NN + ++P LG HL
Sbjct: 389 NGLMAIQLQNNQLENLP---LGIFDHL 412
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 97.9 bits (233), Expect = 8e-20
Identities = 88/330 (26%), Positives = 144/330 (43%), Gaps = 6/330 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L +N + L + F L L +S N++L + +F S ++ L L N L+ +
Sbjct: 106 LSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP 165
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF +++I + F+ L L+ L NRL TF+ L +L+
Sbjct: 166 DGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 225
Query: 170 LSLRNNSILDIPSANLGFVIH-LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L+L+ N I + S L H L+ L LS N I Q+ L +L L L N ++ +
Sbjct: 226 LALQQNQI-GLLSPGLFHNNHNLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKEL 284
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXX 288
F +P+LR L L DN+++ +P + S L L L LS
Sbjct: 285 SPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILS-RNQISFISPGAFNGLTEL 343
Query: 289 XXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALE 348
+ +D F NLQ I + +N ++R++P +F L I ++NN LE
Sbjct: 344 RELSLHTNALQDLDGNVFRMLANLQNISLQNN-RLRQLPGNIFANVNGLMAIQLQNNQLE 402
Query: 349 TLEASHFP-IDRLQELEISGNPFACNCSLL 377
L F + +L EL + NP+ C+ +L
Sbjct: 403 NLPLGIFDHLGKLCELRLYDNPWRCDSDIL 432
Score = 91.5 bits (217), Expect = 7e-18
Identities = 88/363 (24%), Positives = 145/363 (39%), Gaps = 5/363 (1%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FN 66
W A A CP C C A + C A + VP L A + + + I L + F
Sbjct: 16 WGAGLAYHGCPSECTCSRASQV-ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFL 74
Query: 67 LYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXX 126
+ L L I N++ + F + +R+L+L+NN L+ L F G
Sbjct: 75 NISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSS 134
Query: 127 XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F S L+ L N L F+ L L L+L NS+ I
Sbjct: 135 NQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQ 194
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ +L+ L L EN + + L L+ L L N I + FH+ +L+ L LS+
Sbjct: 195 HLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSN 254
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
N+++ +P S +L L+ L L G D+ F
Sbjct: 255 NHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDN-VF 313
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEI 365
+ LQ + ++ N ++ + P F+G +L + + NAL+ L+ + F + LQ + +
Sbjct: 314 SNLRQLQVLILSRN-QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISL 372
Query: 366 SGN 368
N
Sbjct: 373 QNN 375
Score = 44.0 bits (99), Expect = 0.001
Identities = 36/147 (24%), Positives = 60/147 (40%), Gaps = 4/147 (2%)
Query: 46 PEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNF 104
P+ + L N++ L F L L + N I L F + +++ L LS N
Sbjct: 269 PQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQ 328
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
+ + AF G + ++ FR L+ L+ + NNRL F +
Sbjct: 329 ISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANV 388
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHL 191
+ L + L+NN + ++P LG HL
Sbjct: 389 NGLMAIQLQNNQLENLP---LGIFDHL 412
>DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice
variant 4 protein.
Length = 640
Score = 97.1 bits (231), Expect = 1e-19
Identities = 71/254 (27%), Positives = 117/254 (46%), Gaps = 4/254 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C NL VP ++ L+NL N I + + +F L +L
Sbjct: 47 CPSVCSCSNQFSKVICVRKNLRGVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQ 106
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N I + F + L L +N L + AFV I +I
Sbjct: 107 LSRNHIRTIEIGAFNGPANPNTLELFDNRLATIPNGAFVYLSKLKELWLRNNPIESIPSY 166
Query: 136 TFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
F + +L RLD + +++ E FE LS+L+ L+L ++ +IP NL +I L+ L
Sbjct: 167 AFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIP--NLTPLIKLDEL 224
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
DLS N + + L L+ L + + I +++ F +L SL ++L+ NN+TL+P
Sbjct: 225 DLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIRVIERNAFDNLQSLVEINLAHNNLTLLPH 284
Query: 255 SALSKLSNLSHLYL 268
+ L +L ++L
Sbjct: 285 DLFTPLHHLERIHL 298
Score = 90.6 bits (215), Expect = 1e-17
Identities = 74/295 (25%), Positives = 125/295 (42%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N++ + +F+ L L+IL L N I I + L+L +N + +
Sbjct: 81 LNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGPANPNTLELFDNRLATIP 140
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +LK L L NN IES+ F+ +PSLR LDL + ++ I A LSNL
Sbjct: 141 NGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLR 200
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L+ I +F ++LQK+WM + ++R
Sbjct: 201 YLNLA---MCNLREIPNLTPLIKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQS-QIR 256
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L I + +N L L F P+ L+ + + NP+ CNC +LWL W +
Sbjct: 257 VIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWI 316
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C+ P LKG ++ ++ F C + +++
Sbjct: 317 KDMAPSNTACC-------------ARCNTPPNLKGRYIGELDQNYFTCYAPVIVE 358
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 97.1 bits (231), Expect = 1e-19
Identities = 80/265 (30%), Positives = 111/265 (41%), Gaps = 8/265 (3%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLN---PEATLM-NLTHNAIDNLL-YAFNL 67
A+ +CP RC C C N L +VP + P L +L N I N+ + F+
Sbjct: 23 AEPVCPERCDCQHPQHLL-CTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHR 81
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
QL LD+ YN+I L + FE S + L L NN L+ L
Sbjct: 82 LGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGN 141
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
EIS + +F L +L +L N L F PL +L L L +N I +
Sbjct: 142 EISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQ 201
Query: 188 VIHLEYLDLSENLIQQVSRHGLPF--LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L +L+LS N +Q RH F L+ L L L+ N ++ + F LP L L L
Sbjct: 202 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLR 261
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSG 270
N +T + A L L L L G
Sbjct: 262 GNQLTHLAPEAFWGLEALRELRLEG 286
Score = 74.9 bits (176), Expect = 7e-13
Identities = 62/242 (25%), Positives = 101/242 (41%), Gaps = 3/242 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+NI F L L RLD N++ + P+TFE LS L+ L L NN + + L +
Sbjct: 71 ITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPL 130
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L L + N I ++SR L+ L L L+ N + ++ F L +L +L L N
Sbjct: 131 RKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 190
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXX-XXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + +A ++L L L LS + + R F
Sbjct: 191 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQ 250
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
L + + N ++ + P F G L + ++ N L L + P+ L+ L++S
Sbjct: 251 HLPRLGLLSLRGN-QLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLS 309
Query: 367 GN 368
GN
Sbjct: 310 GN 311
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 3/203 (1%)
Query: 51 MNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L NA+ L A F L L + N+I LG F ++R LNLS N L+
Sbjct: 160 LRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSL 219
Query: 110 KDA--FVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
+ A F + ++ + F+ L L L N+L PE F L +L
Sbjct: 220 RHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEAL 279
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N + +P+A L + LE LDLS N + + L L+ L L NN + +
Sbjct: 280 RELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSA 339
Query: 228 VDQLGFHSLPSLRHLDLSDNNMT 250
+ F + P+L LDL N T
Sbjct: 340 LSGDIFAASPALYRLDLDGNGWT 362
Score = 62.1 bits (144), Expect = 5e-09
Identities = 59/210 (28%), Positives = 88/210 (41%), Gaps = 4/210 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAF--VGXXXXXX 121
+F L L + N + L F + +L+L +N ++ L K+AF +G
Sbjct: 150 SFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLN 209
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI- 180
+ S H TF L +L L S N L P F+ L L +LSLR N + +
Sbjct: 210 LSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLA 269
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
P A G L L L N + Q+ L L L+ LDL+ N + ++ F L LR
Sbjct: 270 PEAFWGLEA-LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLR 328
Query: 241 HLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L +N ++ + + L L L G
Sbjct: 329 ELSLRNNALSALSGDIFAASPALYRLDLDG 358
Score = 41.9 bits (94), Expect = 0.006
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 3/161 (1%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
LP ++ L N I ++ FH L LR LDL N + + KLS L LYL
Sbjct: 55 LPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYL 114
Query: 269 SGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPP 328
G R+ +F +L K+ ++ N + +P
Sbjct: 115 -GNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNA-LGALPD 172
Query: 329 RLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
+F L +++++N + L + F + +L+ L +S N
Sbjct: 173 AVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSAN 213
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 97.1 bits (231), Expect = 1e-19
Identities = 88/330 (26%), Positives = 144/330 (43%), Gaps = 6/330 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L +N + L + F L L +S N++L + +F S ++ L L N L+ +
Sbjct: 106 LSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIP 165
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF +++I + F+ L L+ L NRL TF+ L +L+
Sbjct: 166 DGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQE 225
Query: 170 LSLRNNSILDIPSANLGFVIH-LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L+L+ N I + S L H L+ L LS N I Q+ L +L L L N ++ +
Sbjct: 226 LALQQNQI-GLLSPGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKEL 284
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXX 288
F +P+LR L L DN+++ +P + S L L L LS
Sbjct: 285 SLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLILS-RNQISFISPGAFNGLTEL 343
Query: 289 XXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALE 348
+ +D F NLQ I + +N ++R++P +F L I ++NN LE
Sbjct: 344 RELSLHTNALQDLDGNVFRMLANLQNISLQNN-RLRQLPGNIFANVNGLMAIQLQNNQLE 402
Query: 349 TLEASHFP-IDRLQELEISGNPFACNCSLL 377
L F + +L EL + NP+ C+ +L
Sbjct: 403 NLPLGIFDHLGKLCELRLYDNPWRCDSDIL 432
Score = 91.5 bits (217), Expect = 7e-18
Identities = 88/363 (24%), Positives = 145/363 (39%), Gaps = 5/363 (1%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FN 66
W A A CP C C A + C A + VP L A + + + I L + F
Sbjct: 16 WGAGLAYHGCPSECTCSRASQV-ECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFL 74
Query: 67 LYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXX 126
+ L L I N++ + F + +R+L+L+NN L+ L F G
Sbjct: 75 NISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSS 134
Query: 127 XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F S L+ L N L F+ L L L+L NS+ I
Sbjct: 135 NQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQ 194
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ +L+ L L EN + + L L+ L L N I + FH+ +L+ L LS+
Sbjct: 195 HLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSN 254
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
N+++ +P S +L L+ L L G D+ F
Sbjct: 255 NHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDN-VF 313
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEI 365
+ LQ + ++ N ++ + P F+G +L + + NAL+ L+ + F + LQ + +
Sbjct: 314 SNLRQLQVLILSRN-QISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISL 372
Query: 366 SGN 368
N
Sbjct: 373 QNN 375
Score = 61.3 bits (142), Expect = 9e-09
Identities = 48/220 (21%), Positives = 87/220 (39%), Gaps = 1/220 (0%)
Query: 50 LMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L N + ++ + F+ L L + N+I L F +N ++ L LSNN + +L
Sbjct: 201 VLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQL 260
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
F+ + + + F + L L +N + + F L L+
Sbjct: 261 PPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQ 320
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
+L L N I I + L L L N +Q + + L L+++ L NN + +
Sbjct: 321 VLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQL 380
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F ++ L + L +N + +P L L L L
Sbjct: 381 PGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRL 420
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 97.1 bits (231), Expect = 1e-19
Identities = 80/265 (30%), Positives = 111/265 (41%), Gaps = 8/265 (3%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLN---PEATLM-NLTHNAIDNLL-YAFNL 67
A+ +CP RC C C N L +VP + P L +L N I N+ + F+
Sbjct: 99 AEPVCPERCDCQHPQHLL-CTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAFDFHR 157
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
QL LD+ YN+I L + FE S + L L NN L+ L
Sbjct: 158 LGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGN 217
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
EIS + +F L +L +L N L F PL +L L L +N I +
Sbjct: 218 EISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQ 277
Query: 188 VIHLEYLDLSENLIQQVSRHGLPF--LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L +L+LS N +Q RH F L+ L L L+ N ++ + F LP L L L
Sbjct: 278 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLR 337
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSG 270
N +T + A L L L L G
Sbjct: 338 GNQLTHLAPEAFWGLEALRELRLEG 362
Score = 74.9 bits (176), Expect = 7e-13
Identities = 62/242 (25%), Positives = 101/242 (41%), Gaps = 3/242 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+NI F L L RLD N++ + P+TFE LS L+ L L NN + + L +
Sbjct: 147 ITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPL 206
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L L + N I ++SR L+ L L L+ N + ++ F L +L +L L N
Sbjct: 207 RKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNR 266
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXX-XXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + +A ++L L L LS + + R F
Sbjct: 267 IRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQ 326
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
L + + N ++ + P F G L + ++ N L L + P+ L+ L++S
Sbjct: 327 HLPRLGLLSLRGN-QLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLS 385
Query: 367 GN 368
GN
Sbjct: 386 GN 387
Score = 72.1 bits (169), Expect = 5e-12
Identities = 60/203 (29%), Positives = 88/203 (43%), Gaps = 3/203 (1%)
Query: 51 MNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L NA+ L A F L L + N+I LG F ++R LNLS N L+
Sbjct: 236 LRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSL 295
Query: 110 KDA--FVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
+ A F + ++ + F+ L L L N+L PE F L +L
Sbjct: 296 RHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEAL 355
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N + +P+A L + LE LDLS N + + L L+ L L NN + +
Sbjct: 356 RELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSA 415
Query: 228 VDQLGFHSLPSLRHLDLSDNNMT 250
+ F + P+L LDL N T
Sbjct: 416 LSGDIFAASPALYRLDLDGNGWT 438
Score = 62.1 bits (144), Expect = 5e-09
Identities = 59/210 (28%), Positives = 88/210 (41%), Gaps = 4/210 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAF--VGXXXXXX 121
+F L L + N + L F + +L+L +N ++ L K+AF +G
Sbjct: 226 SFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLN 285
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI- 180
+ S H TF L +L L S N L P F+ L L +LSLR N + +
Sbjct: 286 LSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLA 345
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
P A G L L L N + Q+ L L L+ LDL+ N + ++ F L LR
Sbjct: 346 PEAFWGLEA-LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLR 404
Query: 241 HLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L +N ++ + + L L L G
Sbjct: 405 ELSLRNNALSALSGDIFAASPALYRLDLDG 434
Score = 41.9 bits (94), Expect = 0.006
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 3/161 (1%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
LP ++ L N I ++ FH L LR LDL N + + KLS L LYL
Sbjct: 131 LPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYL 190
Query: 269 SGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPP 328
G R+ +F +L K+ ++ N + +P
Sbjct: 191 -GNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNA-LGALPD 248
Query: 329 RLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
+F L +++++N + L + F + +L+ L +S N
Sbjct: 249 AVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSAN 289
>AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein.
Length = 593
Score = 96.7 bits (230), Expect = 2e-19
Identities = 96/368 (26%), Positives = 149/368 (40%), Gaps = 28/368 (7%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF-NLYTQLTVLD 75
CP C C +A C + LE VP L + L++L+ N + L + + L LD
Sbjct: 31 CPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELD 90
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+SYN++ L F + L L N L+ + F G +I
Sbjct: 91 LSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDG 150
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
F +L +L++L+ +N LV P F L+ L L+L ++ +P L + L L
Sbjct: 151 AFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALR 210
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
L E I ++ L L +LK L++ H PSL LD P S
Sbjct: 211 LRELDIGRLPAGALRGLGQLKELEI-------------HLWPSLEALD---------PGS 248
Query: 256 ALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKI 315
+ NLS L ++ I +R + LQ++
Sbjct: 249 LVGL--NLSSLAIT-RCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQEL 305
Query: 316 WMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPI-DRLQELEISGNPFACNC 374
++ + + FHG + + +NAL+TLE + FP D+L L +SGNP C+C
Sbjct: 306 RLS-GACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDC 364
Query: 375 SLLWLWKL 382
LLWL +L
Sbjct: 365 RLLWLLRL 372
Score = 37.1 bits (82), Expect = 0.17
Identities = 35/139 (25%), Positives = 54/139 (38%), Gaps = 2/139 (1%)
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ LD + VG +S++ Q LS L LD S N + PL
Sbjct: 241 LEALDPGSLVGLNLSSLAITRC-NLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPL 299
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
L+ L L + I + + LD+++N +Q + P +L L L+ N
Sbjct: 300 VRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNP 359
Query: 225 IESVDQLGFHSLPSLRHLD 243
+ + D L RHLD
Sbjct: 360 L-TCDCRLLWLLRLRRHLD 377
>AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat
neuronal 6D protein.
Length = 593
Score = 96.7 bits (230), Expect = 2e-19
Identities = 96/368 (26%), Positives = 149/368 (40%), Gaps = 28/368 (7%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF-NLYTQLTVLD 75
CP C C +A C + LE VP L + L++L+ N + L + + L LD
Sbjct: 31 CPAVCDCTSQPQAVLCGHRQLEAVPGGLPLDTELLDLSGNRLWGLQQGMLSRLSLLQELD 90
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+SYN++ L F + L L N L+ + F G +I
Sbjct: 91 LSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIMGPGVFSGLSALTLLDLRLNQIVLFLDG 150
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
F +L +L++L+ +N LV P F L+ L L+L ++ +P L + L L
Sbjct: 151 AFGELGSLQKLEVGDNHLVFVAPGAFAGLAKLSTLTLERCNLSTVPGLALARLPALVALR 210
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
L E I ++ L L +LK L++ H PSL LD P S
Sbjct: 211 LRELDIGRLPAGALRGLGQLKELEI-------------HLWPSLEALD---------PGS 248
Query: 256 ALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKI 315
+ NLS L ++ I +R + LQ++
Sbjct: 249 LVGL--NLSSLAIT-RCNLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPLVRLQEL 305
Query: 316 WMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPI-DRLQELEISGNPFACNC 374
++ + + FHG + + +NAL+TLE + FP D+L L +SGNP C+C
Sbjct: 306 RLS-GACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDC 364
Query: 375 SLLWLWKL 382
LLWL +L
Sbjct: 365 RLLWLLRL 372
Score = 37.1 bits (82), Expect = 0.17
Identities = 35/139 (25%), Positives = 54/139 (38%), Gaps = 2/139 (1%)
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
L+ LD + VG +S++ Q LS L LD S N + PL
Sbjct: 241 LEALDPGSLVGLNLSSLAITRC-NLSSVPFQALYHLSFLRVLDLSQNPISAIPARRLSPL 299
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
L+ L L + I + + LD+++N +Q + P +L L L+ N
Sbjct: 300 VRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNP 359
Query: 225 IESVDQLGFHSLPSLRHLD 243
+ + D L RHLD
Sbjct: 360 L-TCDCRLLWLLRLRRHLD 377
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 96.3 bits (229), Expect = 3e-19
Identities = 106/412 (25%), Positives = 171/412 (41%), Gaps = 54/412 (13%)
Query: 53 LTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ + Y L VLD+S N I ++ + F ++ LNL+ N + L+
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 112 AFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
AF G I+ + V+ F+ L L +LD + NR+ E TF+ L+SL++L
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVL 240
Query: 171 SLRNNSILDIPS-ANLGF----VIHLEY-------------------LDLSENLIQQVSR 206
L+ N+I + A G V+HLEY L LS N I ++ R
Sbjct: 241 KLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL--- 263
G F ++L L L+ N + +D+ L SL L LS N+++ I A L +L
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 264 --SHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNV 321
H +SG S+ + + + ++ N
Sbjct: 361 DLDHNEISGTIEDTSGAFSGLDSLSKLLLLEPSQSAGCSSPSQPHM-SAGGRTLFGN--- 416
Query: 322 KVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL- 379
K++ V R F G L ++ + NA+ +++ F + L+EL IS + F C+C L WL
Sbjct: 417 KIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLP 476
Query: 380 -WKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
W +G+ + + C+ P LKG +P F C
Sbjct: 477 PWLIGRMLQA---------------FVTATCAHPESLKGQSIFSVPPESFVC 513
Score = 70.9 bits (166), Expect = 1e-11
Identities = 72/228 (31%), Positives = 99/228 (43%), Gaps = 6/228 (2%)
Query: 46 PEATLMNLTHNAIDNL-LYAFN-LYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNN 103
P +NL N I L L AF+ L L L +S N+I L F+ + L+L+ N
Sbjct: 163 PPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFKL-PRLTQLDLNRN 221
Query: 104 FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEP 163
++ ++ F G IS + F LS + L N LV +
Sbjct: 222 RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYG 281
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L++L L L NNSI I F L L LS N + ++ L L L L L++N
Sbjct: 282 LTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHN 341
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNM--TLIPTS-ALSKLSNLSHLYL 268
I + + F L SLR LDL N + T+ TS A S L +LS L L
Sbjct: 342 SISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLLL 389
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/196 (28%), Positives = 82/196 (41%), Gaps = 3/196 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L++SYNK ++ FE ++ + L+NN L + +I ++
Sbjct: 73 LNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAV-PSLGAASSHVVSLFLQHNKIRSVE 131
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP-SANLGFVIHLE 192
+ +LE LD S N + F +K L+L N I + A G L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L LS+N I Q+ L L LDLN N I ++ L F L SL L L NN++ +
Sbjct: 192 TLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 253 PTSALSKLSNLSHLYL 268
A LS + L+L
Sbjct: 251 TDGAFWGLSKMHVLHL 266
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/235 (24%), Positives = 94/235 (40%), Gaps = 5/235 (2%)
Query: 139 DLSALER-LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
DL + R L+ S N+ +P FE L +L+ + L NN + +PS H+ L L
Sbjct: 65 DLPSWTRSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAA-SSHVVSLFLQ 123
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
N I+ V L L+ LDL+ N I V F P ++ L+L+ N + + A
Sbjct: 124 HNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAF 183
Query: 258 SKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWM 317
LS S L L I+ F +L+ + +
Sbjct: 184 DGLSR-SLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKL 242
Query: 318 NDNVKVREVPPRLFHGNPKLTNIYMKNNAL-ETLEASHFPIDRLQELEISGNPFA 371
N + ++ F G K+ ++++ N+L E S + + L +L +S N A
Sbjct: 243 QRN-NISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIA 296
>AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens
cDNA FLJ23912 fis, clone CAE04210, highly similar to
Homo sapiens leucine rich repeat containing 4 (LRRC4).
).
Length = 653
Score = 95.1 bits (226), Expect = 6e-19
Identities = 75/296 (25%), Positives = 126/296 (42%), Gaps = 20/296 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L I +F +L+K+W+ N +V
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVM-NSQVS 255
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F G L + + +N L +L F P+ L EL + +P+ C+C +LWL W
Sbjct: 256 LIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHDPWNCDCDILWLAWWF 315
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
+ T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 316 REYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 358
Score = 85.8 bits (203), Expect = 4e-16
Identities = 70/262 (26%), Positives = 112/262 (42%), Gaps = 4/262 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
++ LE L++S N ++ L LK L + N+ + +++ F L SL L+L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAH 275
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ +P + L L L+L
Sbjct: 276 NNLSSLPHDLFTPLRYLVELHL 297
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 94.7 bits (225), Expect = 8e-19
Identities = 68/219 (31%), Positives = 109/219 (49%), Gaps = 3/219 (1%)
Query: 53 LTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ + Y L VLD+S N I ++ + F ++ LNL+ N + L+
Sbjct: 146 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 205
Query: 112 AFVGXXXXXXXXXXXXE-ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
AF G I+ + V+ F+ L L +LD + NR+ E TF+ L+SL++L
Sbjct: 206 AFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVL 264
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
L+ N+I + + + L L N + +V+ L L L L L+NN I + +
Sbjct: 265 KLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 324
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
G+ L L LS NN+T + +L++LS+LS L LS
Sbjct: 325 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLS 363
Score = 74.9 bits (176), Expect = 7e-13
Identities = 61/223 (27%), Positives = 100/223 (44%), Gaps = 5/223 (2%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ N I L + AF L +LT LD++ N+I + F+ + + L L N + +L
Sbjct: 217 LRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLT 275
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
AF G + ++ + L+AL +L SNN + + + L
Sbjct: 276 DGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHE 335
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV- 228
L L N++ + +L + L L LS N I ++ L+ L+ LDL++N I
Sbjct: 336 LVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTI 395
Query: 229 -DQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
D G F L SL L+L N + + A K+ NL L++S
Sbjct: 396 EDTSGAFSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
Score = 73.7 bits (173), Expect = 2e-12
Identities = 70/262 (26%), Positives = 108/262 (41%), Gaps = 6/262 (2%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNL 67
+AA + C C C A + C L +P L +NL++N + + A F
Sbjct: 33 AAAGPRAPCAAACTC--AGDSLDCGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFED 90
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L +++SYNK+ ++ FE ++ + L+NN L +
Sbjct: 91 LPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAV-PSLGAASSHVVSLFLQHN 149
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP-SANLG 186
+I ++ + +LE LD S N + F +K L+L N I + A G
Sbjct: 150 KIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDG 209
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
L L LS+N I Q+ L L LDLN N I ++ L F L SL L L
Sbjct: 210 LSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQR 268
Query: 247 NNMTLIPTSALSKLSNLSHLYL 268
NN++ + A LS + L+L
Sbjct: 269 NNISKLTDGAFWGLSKMHVLHL 290
Score = 66.9 bits (156), Expect = 2e-10
Identities = 57/175 (32%), Positives = 79/175 (45%), Gaps = 3/175 (1%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVT 155
R LNLS N L +D F ++S I F DL L+ + +NN L T
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL-T 129
Query: 156 FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
P S + L L++N I + + L + LE LDLS N I +V P +
Sbjct: 130 AVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPI 189
Query: 216 KHLDLNNNIIESVDQLGFHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
K L+L N I +++ F L SL L LS N +T +P A KL L+ L L+
Sbjct: 190 KELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLN 243
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/197 (30%), Positives = 94/197 (47%), Gaps = 4/197 (2%)
Query: 74 LDISYNKI--LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L+++ N+I L+LG+ + S S + L LS N + +L AF I
Sbjct: 192 LNLAGNRIGTLELGAFDGLSRSLLT-LRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRL 249
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I TF+ L++LE L N + F LS + +L L NS++++ S +L + L
Sbjct: 250 IEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTAL 309
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L LS N I ++ R G F ++L L L+ N + +D+ L SL L LS N+++
Sbjct: 310 HQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISH 369
Query: 252 IPTSALSKLSNLSHLYL 268
I A L +L L L
Sbjct: 370 IAEGAFKGLRSLRVLDL 386
Score = 46.8 bits (106), Expect = 2e-04
Identities = 53/232 (22%), Positives = 97/232 (41%), Gaps = 5/232 (2%)
Query: 139 DLSALER-LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
DL + R L+ S N+L +P FE L +L+ ++L N + +I A + +L+ + L+
Sbjct: 65 DLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLN 124
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
N + V G + L L +N I SV+ + SL LDLS NN+T + +
Sbjct: 125 NNELTAVPSLGAAS-SHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCF 183
Query: 258 SKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWM 317
+ L L+G ++ RAF L ++ +
Sbjct: 184 PHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDL 242
Query: 318 NDNVKVREVPPRLFHGNPKLTNIYM-KNNALETLEASHFPIDRLQELEISGN 368
N N ++R + F G L + + +NN + + + + + ++ L + N
Sbjct: 243 NRN-RIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYN 293
>AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein
protein.
Length = 649
Score = 93.5 bits (222), Expect = 2e-18
Identities = 77/297 (25%), Positives = 126/297 (42%), Gaps = 26/297 (8%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + + +TF L L++L L NSI I + L L+L +N + +
Sbjct: 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIP 139
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSL LDL + + I A L NL
Sbjct: 140 SGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLK 199
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW-MNDNVKV 323
+L L I +F +L+K+W MN + +
Sbjct: 200 YLNLG---MCNIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSHER- 255
Query: 324 REVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WK 381
F G L + + +N L +L F P+ L EL + NP+ C+C +LWL W
Sbjct: 256 -----NAFDGLASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWW 310
Query: 382 LGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVIDA 438
L + T + G +C P+ ++G V++ ++ F CS+ +++DA
Sbjct: 311 LREYIPTNSTCCG-------------RCHAPMHMRGRYLVEVDQASFQCSAPFIMDA 354
Score = 79.8 bits (188), Expect = 2e-14
Identities = 73/265 (27%), Positives = 114/265 (43%), Gaps = 14/265 (5%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
+A+A CP C C + C L VP + +NL N I + F
Sbjct: 38 AASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRH 97
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
L VL + N I + F + + L L +N+L + AF
Sbjct: 98 LHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNN 157
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLG 186
I +I F + +L RLD + + + E FE L +LK L+L +I D+P NL
Sbjct: 158 PIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP--NLT 215
Query: 187 FVIHLEYLDLSENLIQQV---SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
++ LE L++S N ++ S HGL LK+L ++ S ++ F L SL L+
Sbjct: 216 PLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLW-------VMNSHERNAFDGLASLVELN 268
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYL 268
L+ NN++ +P + L L L+L
Sbjct: 269 LAHNNLSSLPHDLFTPLRYLVELHL 293
Score = 56.8 bits (131), Expect = 2e-07
Identities = 44/143 (30%), Positives = 65/143 (45%), Gaps = 3/143 (2%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TFR L LE L N + E F L+SL L L +N + IPS ++
Sbjct: 87 IQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYL 146
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDN 247
L L L N I+ + + + L LDL +E + + F L +L++L+L
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 248 NMTLIPTSALSKLSNLSHLYLSG 270
N+ +P L+ L L L +SG
Sbjct: 207 NIKDMPN--LTPLVGLEELEMSG 227
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 91.9 bits (218), Expect = 5e-18
Identities = 73/261 (27%), Positives = 111/261 (42%), Gaps = 5/261 (1%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLY 68
+ AA LC C CD R C+ L VP L+ ++++ N I L AF +
Sbjct: 103 SGAAPPLCAAPCSCDGD-RRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF 161
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
L L ++ N + + + E++ L L NN LK + +A G
Sbjct: 162 PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANH 221
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+++ +F L L L +N L L +L+ L+L N I IP +
Sbjct: 222 ITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNL 281
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L N I+ +S+H L L+ LDLN N + Q +LPSL+ L N+
Sbjct: 282 SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ-AIKALPSLKELGFHSNS 340
Query: 249 MTLIPTSAL--SKLSNLSHLY 267
+++IP A + L HLY
Sbjct: 341 ISVIPDGAFDGNPLLRTIHLY 361
Score = 74.1 bits (174), Expect = 1e-12
Identities = 52/172 (30%), Positives = 79/172 (45%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L++S N + +L +DAF ++S IH + L L+ L NN+L T
Sbjct: 143 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 202
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
E LS+L+ L L N I +P + ++ L +L L +N + +V H L L L+
Sbjct: 203 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 262
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L N I S+ F +L SL L L +N + + L NL L L+
Sbjct: 263 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLN 314
Score = 66.9 bits (156), Expect = 2e-10
Identities = 56/216 (25%), Positives = 91/216 (42%), Gaps = 9/216 (4%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N + A L L N I + F+ N +R ++L +N L +
Sbjct: 311 LDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 370
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + VQ F +L+ LE L + ++ + + L
Sbjct: 371 SAFHNLSDLHSLVIRGASM----VQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKML 426
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N+I D+PS N LE + L N I Q+ L L+ LDL+ N+I
Sbjct: 427 RTLDLSYNNIRDLPSFNGCHA--LEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHE 484
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ F +L + +LD+S N +T PT L+ L+ L
Sbjct: 485 IHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL 520
Score = 62.5 bits (145), Expect = 4e-09
Identities = 44/131 (33%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Query: 140 LSAL-ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
LSA + LD S N + + F+ L+ L L N + I L + L+ L L
Sbjct: 136 LSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQN 195
Query: 199 NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
N ++ V + L L+ L L+ N I SV + F L LRHL L DN++T +P LS
Sbjct: 196 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 255
Query: 259 KLSNLSHLYLS 269
L L L L+
Sbjct: 256 NLPTLQALTLA 266
Score = 51.2 bits (117), Expect = 9e-06
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 7/222 (3%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I +L + F+ L LD++YN + + + ++ ++ L +N + +
Sbjct: 286 VLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSISVI 344
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF G +S + F +LS L L +V P + L+
Sbjct: 345 PDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LE 403
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV-SRHGLPFLKELKHLDLNNNIIES 227
L+L I IP+ L LDLS N I+ + S +G L+E+ L N I
Sbjct: 404 SLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEIS---LQRNQIYQ 460
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + F L SLR LDLS N + I + A + L +++L +S
Sbjct: 461 IKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVS 502
Score = 48.4 bits (110), Expect = 7e-05
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+SYN I DL S F + ++L N + ++ + F G I
Sbjct: 426 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 483
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
IH + F L + LD S N L +F E L+ LK++
Sbjct: 484 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLV 523
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 3/177 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L + + N + +G+ F + S++ L + + + + G
Sbjct: 348 AFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPN-LTGTVHLESLT 406
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
+IS+I ++ L LD S N + +F +L+ +SL+ N I I
Sbjct: 407 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEG 464
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
+I L LDLS NLI ++ L + +LD++ N + S G + L L+
Sbjct: 465 TFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLK 521
Score = 42.7 bits (96), Expect = 0.003
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
+F ALE + N++ + TF+ L SL+IL L N I +I S + + LD
Sbjct: 441 SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLD 500
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+S N + GL L +LK L N + E++ F +L SL
Sbjct: 501 VSFNELTSFPTEGLNGLNQLK-LVGNFKLKEALAAKDFVNLRSL 543
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 91.5 bits (217), Expect = 7e-18
Identities = 87/368 (23%), Positives = 148/368 (40%), Gaps = 15/368 (4%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF +L L+++ + L+L + F + + + L L+ N L+ L + F
Sbjct: 92 AFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLH 151
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ + + F+ L+ L+ L+ + N L E F PL+SL+ L L NN++ +P
Sbjct: 152 LQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQG 211
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
G + L+ L L N I ++ L L+ L L N I + F SL +L L
Sbjct: 212 VFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLS 271
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L N + ++P + L L L+ + +
Sbjct: 272 LQWNMLRVLPAGLFAHTPCLVGLSLT-HNQLETVAEGTFAHLSNLRSLMLSYNAITHLPA 330
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPID-RLQE 362
F D L K+++ N + + P LF KL + + N L TL F + L
Sbjct: 331 GIFRDLEELVKLYLGSN-NLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFN 389
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + GNP+ C+C L +L+ + T + N + C+GP LKG +
Sbjct: 390 LALHGNPWQCDCHLAYLFNW---LQQYTDRLLNIQTY---------CAGPAYLKGQVVPA 437
Query: 423 IPESEFGC 430
+ E + C
Sbjct: 438 LNEKQLVC 445
Score = 76.2 bits (179), Expect = 3e-13
Identities = 52/185 (28%), Positives = 86/185 (46%)
Query: 84 LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSAL 143
L + F SN + + N L + DAF G N+ F +L++L
Sbjct: 64 LETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSL 123
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
+L + N L F+ L++L+ L L+ N + +P + HL+ L+L++NL+ Q
Sbjct: 124 GKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQ 183
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ L L+ L L+NN + + Q F L SL+ L L NN++ +P S+L L
Sbjct: 184 LPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCL 243
Query: 264 SHLYL 268
L+L
Sbjct: 244 ERLWL 248
>BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein.
Length = 420
Score = 91.5 bits (217), Expect = 7e-18
Identities = 74/295 (25%), Positives = 124/295 (42%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + +TF+ L L+IL L N + I + L L+L +N + V
Sbjct: 91 LNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVP 150
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSLR LDL + + I +A L NL
Sbjct: 151 TQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLR 210
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L + I +F +L+K+W+ + +V
Sbjct: 211 YLNLG---MCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLM-HAQVA 266
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L + + +N L +L F P+ RL+ + ++ NP+ CNC +LWL W L
Sbjct: 267 TIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWL 326
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C P LKG ++ +S F C + +++
Sbjct: 327 KETVPSNTTCC-------------ARCHAPAGLKGRYIGELDQSHFTCYAPVIVE 368
Score = 90.6 bits (215), Expect = 1e-17
Identities = 69/257 (26%), Positives = 108/257 (42%), Gaps = 4/257 (1%)
Query: 15 TLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTV 73
T CPV C C + C +L VP + +NL N I + F L +
Sbjct: 55 TSCPVACSCSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEI 114
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L +S N + + F + L L +N L + AF I +I
Sbjct: 115 LQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIP 174
Query: 134 VQTFRDLSALERLDFSN-NRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F + +L RLD RL FE L +L+ L+L ++ DIP NL ++ LE
Sbjct: 175 SYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIP--NLTALVRLE 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L+LS N + + L L+ L L + + ++++ F L SL L+LS NN+ +
Sbjct: 233 ELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 292
Query: 253 PTSALSKLSNLSHLYLS 269
P + L L ++L+
Sbjct: 293 PHDLFTPLHRLERVHLN 309
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 7/154 (4%)
Query: 27 LRAASCANANLEIVP-IQLNPEATLMNLTHNAIDNLLY----AFNLYTQLTVLDISYNKI 81
LR N +E +P N +L L + L Y AF L L++ +
Sbjct: 160 LRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNL 219
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
D+ N + + L LS N L + +F G +++ I F DL
Sbjct: 220 KDI--PNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK 277
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+LE L+ S+N L++ + F PL L+ + L +N
Sbjct: 278 SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for
IMAGE:5200456) protein.
Length = 634
Score = 91.5 bits (217), Expect = 7e-18
Identities = 74/295 (25%), Positives = 124/295 (42%), Gaps = 20/295 (6%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+ N + +TF+ L L+IL L N + I + L L+L +N + V
Sbjct: 91 LNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVP 150
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLS 264
+L +L+ L L NN IES+ F+ +PSLR LDL + + I +A L NL
Sbjct: 151 TQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLR 210
Query: 265 HLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVR 324
+L L + I +F +L+K+W+ + +V
Sbjct: 211 YLNLG---MCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLM-HAQVA 266
Query: 325 EVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL-WKL 382
+ F L + + +N L +L F P+ RL+ + ++ NP+ CNC +LWL W L
Sbjct: 267 TIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWL 326
Query: 383 GKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCSSGWVID 437
+ + T +C P LKG ++ +S F C + +++
Sbjct: 327 KETVPSNTTCC-------------ARCHAPAGLKGRYIGELDQSHFTCYAPVIVE 368
Score = 90.6 bits (215), Expect = 1e-17
Identities = 69/257 (26%), Positives = 108/257 (42%), Gaps = 4/257 (1%)
Query: 15 TLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTV 73
T CPV C C + C +L VP + +NL N I + F L +
Sbjct: 55 TSCPVACSCSNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEI 114
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L +S N + + F + L L +N L + AF I +I
Sbjct: 115 LQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIP 174
Query: 134 VQTFRDLSALERLDFSN-NRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F + +L RLD RL FE L +L+ L+L ++ DIP NL ++ LE
Sbjct: 175 SYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIP--NLTALVRLE 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L+LS N + + L L+ L L + + ++++ F L SL L+LS NN+ +
Sbjct: 233 ELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 292
Query: 253 PTSALSKLSNLSHLYLS 269
P + L L ++L+
Sbjct: 293 PHDLFTPLHRLERVHLN 309
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/154 (25%), Positives = 63/154 (40%), Gaps = 7/154 (4%)
Query: 27 LRAASCANANLEIVP-IQLNPEATLMNLTHNAIDNLLY----AFNLYTQLTVLDISYNKI 81
LR N +E +P N +L L + L Y AF L L++ +
Sbjct: 160 LRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNL 219
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
D+ N + + L LS N L + +F G +++ I F DL
Sbjct: 220 KDI--PNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLK 277
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+LE L+ S+N L++ + F PL L+ + L +N
Sbjct: 278 SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 311
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 91.5 bits (217), Expect = 7e-18
Identities = 87/368 (23%), Positives = 148/368 (40%), Gaps = 15/368 (4%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF +L L+++ + L+L + F + + + L L+ N L+ L + F
Sbjct: 92 AFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLH 151
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ + + F+ L+ L+ L+ + N L E F PL+SL+ L L NN++ +P
Sbjct: 152 LQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQG 211
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
G + L+ L L N I ++ L L+ L L N I + F SL +L L
Sbjct: 212 VFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLS 271
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L N + ++P + L L L+ + +
Sbjct: 272 LQWNMLRVLPAGLFAHTPCLVGLSLT-HNQLETVAEGTFAHLSNLRSLMLSYNAITHLPA 330
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPID-RLQE 362
F D L K+++ N + + P LF KL + + N L TL F + L
Sbjct: 331 GIFRDLEELVKLYLGSN-NLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFN 389
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + GNP+ C+C L +L+ + T + N + C+GP LKG +
Sbjct: 390 LALHGNPWQCDCHLAYLFNW---LQQYTDRLLNIQTY---------CAGPAYLKGQVVPA 437
Query: 423 IPESEFGC 430
+ E + C
Sbjct: 438 LNEKQLVC 445
Score = 76.2 bits (179), Expect = 3e-13
Identities = 52/185 (28%), Positives = 86/185 (46%)
Query: 84 LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSAL 143
L + F SN + + N L + DAF G N+ F +L++L
Sbjct: 64 LETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSL 123
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
+L + N L F+ L++L+ L L+ N + +P + HL+ L+L++NL+ Q
Sbjct: 124 GKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQ 183
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ L L+ L L+NN + + Q F L SL+ L L NN++ +P S+L L
Sbjct: 184 LPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCL 243
Query: 264 SHLYL 268
L+L
Sbjct: 244 ERLWL 248
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 91.1 bits (216), Expect = 1e-17
Identities = 83/362 (22%), Positives = 162/362 (44%), Gaps = 13/362 (3%)
Query: 26 ALRAASCANANLEIVPIQLNPEA---TLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
+LR N LE +P L P + TL++L N I +L + L LD+S N I
Sbjct: 99 SLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDL 140
+L + F + ++++L L++N + ++ F IS I + F+ L
Sbjct: 158 SELQTA-FPA-LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-L 214
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
L+ L+ + N++ + TF+ L +LK L ++ N + + + ++E L L N
Sbjct: 215 PQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNN 274
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ ++++ L L L+ L L+ N I + + L LDL+ N+++ + S+ L
Sbjct: 275 LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 334
Query: 261 SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR--AFVDNINLQKIWMN 318
S L+ L++ I+ AF L+++ +
Sbjct: 335 SLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQ 394
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLL 377
N ++R + + F G L ++ + +NA+ +L+ + F + +LQ+L ++ + C+C L
Sbjct: 395 GN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLK 453
Query: 378 WL 379
WL
Sbjct: 454 WL 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 84/366 (22%), Positives = 149/366 (40%), Gaps = 14/366 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S AA+ CP C C L C+ L +P L ++L+HN + + + +
Sbjct: 39 SGVAAERPCPTTCRCLGDL--LDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSH 96
Query: 69 TQ-LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Q L + ++ N++ + + S + + L+L+ N + + +
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVS-ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSANLG 186
IS + QT L+ L ++NR+ + EP F+ L ++L +L L N I IP +
Sbjct: 156 NISEL--QTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP-PKMF 212
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ L++L+L+ N I+ V L LK L + N + + F L ++ L L
Sbjct: 213 KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDH 272
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
NN+T I L L L L+LS R+D +F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLS-QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSF 331
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRLQE 362
+ L + + +N +V + F G L + +KNN +E + + +D+L+
Sbjct: 332 LGLSLLNTLHIGNN-RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRR 390
Query: 363 LEISGN 368
L + GN
Sbjct: 391 LILQGN 396
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 91.1 bits (216), Expect = 1e-17
Identities = 83/362 (22%), Positives = 162/362 (44%), Gaps = 13/362 (3%)
Query: 26 ALRAASCANANLEIVPIQLNPEA---TLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
+LR N LE +P L P + TL++L N I +L + L LD+S N I
Sbjct: 99 SLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDL 140
+L + F + ++++L L++N + ++ F IS I + F+ L
Sbjct: 158 SELQTA-FPA-LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-L 214
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
L+ L+ + N++ + TF+ L +LK L ++ N + + + ++E L L N
Sbjct: 215 PQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNN 274
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ ++++ L L L+ L L+ N I + + L LDL+ N+++ + S+ L
Sbjct: 275 LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 334
Query: 261 SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR--AFVDNINLQKIWMN 318
S L+ L++ I+ AF L+++ +
Sbjct: 335 SLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQ 394
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLL 377
N ++R + + F G L ++ + +NA+ +L+ + F + +LQ+L ++ + C+C L
Sbjct: 395 GN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLK 453
Query: 378 WL 379
WL
Sbjct: 454 WL 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 84/366 (22%), Positives = 149/366 (40%), Gaps = 14/366 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S AA+ CP C C L C+ L +P L ++L+HN + + + +
Sbjct: 39 SGVAAERPCPTTCRCLGDL--LDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSH 96
Query: 69 TQ-LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Q L + ++ N++ + + S + + L+L+ N + + +
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVS-ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSANLG 186
IS + QT L+ L ++NR+ + EP F+ L ++L +L L N I IP +
Sbjct: 156 NISEL--QTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP-PKMF 212
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ L++L+L+ N I+ V L LK L + N + + F L ++ L L
Sbjct: 213 KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDH 272
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
NN+T I L L L L+LS R+D +F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLS-QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSF 331
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRLQE 362
+ L + + +N +V + F G L + +KNN +E + + +D+L+
Sbjct: 332 LGLSLLNTLHIGNN-RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRR 390
Query: 363 LEISGN 368
L + GN
Sbjct: 391 LILQGN 396
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 91.1 bits (216), Expect = 1e-17
Identities = 83/362 (22%), Positives = 162/362 (44%), Gaps = 13/362 (3%)
Query: 26 ALRAASCANANLEIVPIQLNPEA---TLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
+LR N LE +P L P + TL++L N I +L + L LD+S N I
Sbjct: 99 SLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDL 140
+L + F + ++++L L++N + ++ F IS I + F+ L
Sbjct: 158 SELQTA-FPA-LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-L 214
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
L+ L+ + N++ + TF+ L +LK L ++ N + + + ++E L L N
Sbjct: 215 PQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNN 274
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ ++++ L L L+ L L+ N I + + L LDL+ N+++ + S+ L
Sbjct: 275 LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 334
Query: 261 SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR--AFVDNINLQKIWMN 318
S L+ L++ I+ AF L+++ +
Sbjct: 335 SLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQ 394
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLL 377
N ++R + + F G L ++ + +NA+ +L+ + F + +LQ+L ++ + C+C L
Sbjct: 395 GN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLK 453
Query: 378 WL 379
WL
Sbjct: 454 WL 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 84/366 (22%), Positives = 149/366 (40%), Gaps = 14/366 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S AA+ CP C C L C+ L +P L ++L+HN + + + +
Sbjct: 39 SGVAAERPCPTTCRCLGDL--LDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSH 96
Query: 69 TQ-LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Q L + ++ N++ + + S + + L+L+ N + + +
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVS-ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSANLG 186
IS + QT L+ L ++NR+ + EP F+ L ++L +L L N I IP +
Sbjct: 156 NISEL--QTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP-PKMF 212
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ L++L+L+ N I+ V L LK L + N + + F L ++ L L
Sbjct: 213 KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDH 272
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
NN+T I L L L L+LS R+D +F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLS-QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSF 331
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRLQE 362
+ L + + +N +V + F G L + +KNN +E + + +D+L+
Sbjct: 332 LGLSLLNTLHIGNN-RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRR 390
Query: 363 LEISGN 368
L + GN
Sbjct: 391 LILQGN 396
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 91.1 bits (216), Expect = 1e-17
Identities = 83/362 (22%), Positives = 162/362 (44%), Gaps = 13/362 (3%)
Query: 26 ALRAASCANANLEIVPIQLNPEA---TLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
+LR N LE +P L P + TL++L N I +L + L LD+S N I
Sbjct: 39 SLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 97
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDL 140
+L + F + ++++L L++N + ++ F IS I + F+ L
Sbjct: 98 SELQTA-FPA-LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-L 154
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
L+ L+ + N++ + TF+ L +LK L ++ N + + + ++E L L N
Sbjct: 155 PQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNN 214
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ ++++ L L L+ L L+ N I + + L LDL+ N+++ + S+ L
Sbjct: 215 LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 274
Query: 261 SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR--AFVDNINLQKIWMN 318
S L+ L++ I+ AF L+++ +
Sbjct: 275 SLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQ 334
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLL 377
N ++R + + F G L ++ + +NA+ +L+ + F + +LQ+L ++ + C+C L
Sbjct: 335 GN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLK 393
Query: 378 WL 379
WL
Sbjct: 394 WL 395
Score = 68.9 bits (161), Expect = 4e-11
Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 5/209 (2%)
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
LL++ L ++ D+S+N++ + + + +R + L+NN L+ + V
Sbjct: 6 LLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPV-SANIT 64
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
I I + ++ +LE LD S+N + E +T P LK L L +N + +
Sbjct: 65 LLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI--SELQTAFPALQLKYLYLNSNRVTSM 122
Query: 181 -PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
P L L L+ N I + L +L+HL+LN N I++VD L F L +L
Sbjct: 123 EPGYFDNLANTLLVLKLNRNRISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGAL 181
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L + N +T + A LSN+ L L
Sbjct: 182 KSLKMQRNGVTKLMDGAFWGLSNMEILQL 210
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 10/188 (5%)
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+L + H+ DLS N + + + L+ L+ + LNNN +E++ LG S ++ L
Sbjct: 9 SLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVS-ANITLLS 67
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L+ N + I L + +L L LS E
Sbjct: 68 LAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSME---- 123
Query: 304 RAFVDNI--NLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRL 360
+ DN+ L + +N N ++ +PP++F P+L ++ + N ++ ++ F + L
Sbjct: 124 PGYFDNLANTLLVLKLNRN-RISAIPPKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGAL 181
Query: 361 QELEISGN 368
+ L++ N
Sbjct: 182 KSLKMQRN 189
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 91.1 bits (216), Expect = 1e-17
Identities = 83/362 (22%), Positives = 162/362 (44%), Gaps = 13/362 (3%)
Query: 26 ALRAASCANANLEIVPIQLNPEA---TLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
+LR N LE +P L P + TL++L N I +L + L LD+S N I
Sbjct: 99 SLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNI 157
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE-ISNIHVQTFRDL 140
+L + F + ++++L L++N + ++ F IS I + F+ L
Sbjct: 158 SELQTA-FPA-LQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFK-L 214
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
L+ L+ + N++ + TF+ L +LK L ++ N + + + ++E L L N
Sbjct: 215 PQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNN 274
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ ++++ L L L+ L L+ N I + + L LDL+ N+++ + S+ L
Sbjct: 275 LTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGL 334
Query: 261 SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR--AFVDNINLQKIWMN 318
S L+ L++ I+ AF L+++ +
Sbjct: 335 SLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQ 394
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLL 377
N ++R + + F G L ++ + +NA+ +L+ + F + +LQ+L ++ + C+C L
Sbjct: 395 GN-RIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLK 453
Query: 378 WL 379
WL
Sbjct: 454 WL 455
Score = 70.5 bits (165), Expect = 1e-11
Identities = 84/366 (22%), Positives = 149/366 (40%), Gaps = 14/366 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S AA+ CP C C L C+ L +P L ++L+HN + + + +
Sbjct: 39 SGVAAERPCPTTCRCLGDL--LDCSRKRLARLPEPLPSWVARLDLSHNRLSFIKASSMSH 96
Query: 69 TQ-LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Q L + ++ N++ + + S + + L+L+ N + + +
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVS-ANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSN 155
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL-SSLKILSLRNNSILDIPSANLG 186
IS + QT L+ L ++NR+ + EP F+ L ++L +L L N I IP +
Sbjct: 156 NISEL--QTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP-PKMF 212
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD 246
+ L++L+L+ N I+ V L LK L + N + + F L ++ L L
Sbjct: 213 KLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDH 272
Query: 247 NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAF 306
NN+T I L L L L+LS R+D +F
Sbjct: 273 NNLTEITKGWLYGLLMLQELHLS-QNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSF 331
Query: 307 VDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNN----ALETLEASHFPIDRLQE 362
+ L + + +N +V + F G L + +KNN +E + + +D+L+
Sbjct: 332 LGLSLLNTLHIGNN-RVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRR 390
Query: 363 LEISGN 368
L + GN
Sbjct: 391 LILQGN 396
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 90.6 bits (215), Expect = 1e-17
Identities = 87/368 (23%), Positives = 147/368 (39%), Gaps = 15/368 (4%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF +L L+++ + L+L + F + + + L L+ N L+ L + F
Sbjct: 92 AFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLH 151
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
+ + + F+ L+ L+ L+ + N L E F PL+SL+ L L NN++ +P
Sbjct: 152 LQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQG 211
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
G + L+ L L N I ++ L L+ L L N I + F SL +L L
Sbjct: 212 VFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLS 271
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L N + ++P + L L L+ + +
Sbjct: 272 LQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITH-LPA 330
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPID-RLQE 362
F D L K+++ N + + P LF KL + + N L TL F + L
Sbjct: 331 GIFRDLEELVKLYLGSN-NLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFN 389
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + GNP+ C+C L +L+ + T + N + C+GP LKG +
Sbjct: 390 LALHGNPWQCDCHLAYLFNW---LQQYTDRLLNIQTY---------CAGPAYLKGQVVPA 437
Query: 423 IPESEFGC 430
+ E + C
Sbjct: 438 LNEKQLVC 445
Score = 84.6 bits (200), Expect = 8e-16
Identities = 80/365 (21%), Positives = 137/365 (37%), Gaps = 4/365 (1%)
Query: 6 WTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYA 64
WT A+ P CD ++ C++ L VP+ + P + + L A
Sbjct: 9 WTSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETSFTTLETRA 68
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F LT + ++ + F + L ++ + L + F
Sbjct: 69 FGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNLTSLGKLTL 128
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
+ + F+ L+ALE L NRL F+PL+ LK L+L N + +P
Sbjct: 129 NFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEEL 188
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
+ L+ L LS N + + + L L+ L L++N I + F L L L L
Sbjct: 189 FHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWL 248
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
N +T +P S + L NL+ L L E +
Sbjct: 249 QRNAITHLPLSIFASLGNLTFLSLQ-WNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEG 307
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQEL 363
F NL+ + ++ N + +P +F +L +Y+ +N L L + F + +L+ L
Sbjct: 308 TFAHLSNLRSLMLSYNA-ITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELL 366
Query: 364 EISGN 368
+S N
Sbjct: 367 SLSKN 371
Score = 54.0 bits (124), Expect = 1e-06
Identities = 37/130 (28%), Positives = 59/130 (45%), Gaps = 1/130 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L NAI +L L F LT L + +N + L + F + L+L++N L+ + +
Sbjct: 248 LQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEG 307
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F I+++ FRDL L +L +N L P F+ LS L++LS
Sbjct: 308 TFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLS 367
Query: 172 LRNNSILDIP 181
L N + +P
Sbjct: 368 LSKNQLTTLP 377
Score = 41.9 bits (94), Expect = 0.006
Identities = 53/225 (23%), Positives = 91/225 (40%), Gaps = 4/225 (1%)
Query: 27 LRAASCANANLEIVPIQL-NPEATL--MNLTHNAIDNLLYA-FNLYTQLTVLDISYNKIL 82
L+ + A L +P +L +P +L + L++NA+ L F L L + N I
Sbjct: 171 LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNIS 230
Query: 83 DLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA 142
+L + F + L L N + L F + + F
Sbjct: 231 ELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPC 290
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L L ++N+L T TF LS+L+ L L N+I +P+ + L L L N +
Sbjct: 291 LVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLT 350
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ L +L+ L L+ N + ++ + F + +L +L L N
Sbjct: 351 ALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGN 395
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 90.6 bits (215), Expect = 1e-17
Identities = 85/350 (24%), Positives = 148/350 (42%), Gaps = 27/350 (7%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C + L P +L ++ L N I + Y+ + LT LD+S N + + + N +
Sbjct: 55 CNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTSLDLSQNNLSSVTNINVKK 114
Query: 92 NSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
++ + L N L L + +S I F L L RL ++N
Sbjct: 115 MPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN 174
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
RL + F+ L +L+IL + N I+ I N +I+L L ++ + ++ + L
Sbjct: 175 RLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVG 234
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGX 271
L+ L+ + +N + V + + +L+ LDL+ N + I SN+ HL G
Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG---DFSNMLHLKELGI 291
Query: 272 XXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNI-NLQKIWMNDNVKVREVPPRL 330
IDS A VDN+ +L+KI +N ++ + P
Sbjct: 292 NNMPELIS---------------------IDSLA-VDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 331 FHGNPKLTNIYMKNNALETL-EASHFPIDRLQELEISGNPFACNCSLLWL 379
F PKL ++ + +NAL L + + L+E+ I NP C+C + W+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWM 379
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 90.2 bits (214), Expect = 2e-17
Identities = 85/350 (24%), Positives = 148/350 (42%), Gaps = 27/350 (7%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C + L P +L ++ L N I + Y+ + LT LD+S N + + + N +
Sbjct: 55 CNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKK 114
Query: 92 NSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
++ + L N L L + +S I F L L RL ++N
Sbjct: 115 MPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN 174
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
RL + F+ L +L+IL + N I+ I N +I+L L ++ + ++ + L
Sbjct: 175 RLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVG 234
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGX 271
L+ L+ + +N + V + + +L+ LDL+ N + I SN+ HL G
Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG---DFSNMLHLKELGI 291
Query: 272 XXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNI-NLQKIWMNDNVKVREVPPRL 330
IDS A VDN+ +L+KI +N ++ + P
Sbjct: 292 NNMPELIS---------------------IDSLA-VDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 331 FHGNPKLTNIYMKNNALETL-EASHFPIDRLQELEISGNPFACNCSLLWL 379
F PKL ++ + +NAL L + + L+E+ I NP C+C + W+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWM 379
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 90.2 bits (214), Expect = 2e-17
Identities = 85/350 (24%), Positives = 148/350 (42%), Gaps = 27/350 (7%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C + L P +L ++ L N I + Y+ + LT LD+S N + + + N +
Sbjct: 55 CNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKK 114
Query: 92 NSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
++ + L N L L + +S I F L L RL ++N
Sbjct: 115 MPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN 174
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
RL + F+ L +L+IL + N I+ I N +I+L L ++ + ++ + L
Sbjct: 175 RLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVG 234
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGX 271
L+ L+ + +N + V + + +L+ LDL+ N + I SN+ HL G
Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG---DFSNMLHLKELGI 291
Query: 272 XXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNI-NLQKIWMNDNVKVREVPPRL 330
IDS A VDN+ +L+KI +N ++ + P
Sbjct: 292 NNMPELIS---------------------IDSLA-VDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 331 FHGNPKLTNIYMKNNALETL-EASHFPIDRLQELEISGNPFACNCSLLWL 379
F PKL ++ + +NAL L + + L+E+ I NP C+C + W+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWM 379
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 90.2 bits (214), Expect = 2e-17
Identities = 85/350 (24%), Positives = 148/350 (42%), Gaps = 27/350 (7%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C + L P +L ++ L N I + Y+ + LT LD+S N + + + N +
Sbjct: 55 CNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKK 114
Query: 92 NSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
++ + L N L L + +S I F L L RL ++N
Sbjct: 115 MPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN 174
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
RL + F+ L +L+IL + N I+ I N +I+L L ++ + ++ + L
Sbjct: 175 RLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVG 234
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGX 271
L+ L+ + +N + V + + +L+ LDL+ N + I SN+ HL G
Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG---DFSNMLHLKELGI 291
Query: 272 XXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNI-NLQKIWMNDNVKVREVPPRL 330
IDS A VDN+ +L+KI +N ++ + P
Sbjct: 292 NNMPELIS---------------------IDSLA-VDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 331 FHGNPKLTNIYMKNNALETL-EASHFPIDRLQELEISGNPFACNCSLLWL 379
F PKL ++ + +NAL L + + L+E+ I NP C+C + W+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWM 379
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 90.2 bits (214), Expect = 2e-17
Identities = 85/350 (24%), Positives = 148/350 (42%), Gaps = 27/350 (7%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C + L P +L ++ L N I + Y+ + LT LD+S N + + + N +
Sbjct: 55 CNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKK 114
Query: 92 NSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
++ + L N L L + +S I F L L RL ++N
Sbjct: 115 MPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSN 174
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
RL + F+ L +L+IL + N I+ I N +I+L L ++ + ++ + L
Sbjct: 175 RLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVG 234
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGX 271
L+ L+ + +N + V + + +L+ LDL+ N + I SN+ HL G
Sbjct: 235 LENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG---DFSNMLHLKELGI 291
Query: 272 XXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNI-NLQKIWMNDNVKVREVPPRL 330
IDS A VDN+ +L+KI +N ++ + P
Sbjct: 292 NNMPELIS---------------------IDSLA-VDNLPDLRKIEATNNPRLSYIHPNA 329
Query: 331 FHGNPKLTNIYMKNNALETL-EASHFPIDRLQELEISGNPFACNCSLLWL 379
F PKL ++ + +NAL L + + L+E+ I NP C+C + W+
Sbjct: 330 FFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWM 379
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 89.8 bits (213), Expect = 2e-17
Identities = 61/197 (30%), Positives = 96/197 (48%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I +L + F S S++ L+L +N + + +DAF G +I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF L L+ LD S N+L + PE F L L+ L LR+NS+ IP LE+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDLS N ++ ++R+G L +L+ L L +N + ++ F L SL L L N ++ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 254 TSALSKLSNLSHLYLSG 270
L L L+G
Sbjct: 246 CGMEWTWGTLEKLDLTG 262
Score = 84.2 bits (199), Expect = 1e-15
Identities = 67/226 (29%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T ++L HN I + AF +L L +S NKI L + F +++L+LS N L
Sbjct: 86 QLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F D +LE LD S NRL + F L
Sbjct: 146 SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNI 224
L+ L L +N + I A+ + L L L N I ++ G+ + L+ LDL N
Sbjct: 206 KLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC-GMEWTWGTLEKLDLTGNE 264
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
I+++D F ++P+L+ L + +N + + + L+ L +L+ + LSG
Sbjct: 265 IKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Score = 55.2 bits (127), Expect = 6e-07
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+S N++ L F ++R L+L +N L +++ F+ +IS
Sbjct: 183 LEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKIS 242
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
N+ LE+LD + N + + FE + +LKIL + NN + + S L +
Sbjct: 243 NLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 302
Query: 191 LEYLDLSENL 200
L + LS NL
Sbjct: 303 LTTVGLSGNL 312
Score = 38.3 bits (85), Expect = 0.071
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 229 DQLGFHSLPSLRH-----LDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
D GFHS+P+ L L N++T + + S L+ L+L
Sbjct: 48 DSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQG 107
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + F INLQ + ++ N ++ + P LF+G KL ++++
Sbjct: 108 LYKLKELILSSNKIFY-LPNTTFTQLINLQNLDLSFN-QLSSLHPELFYGLRKLQTLHLR 165
Query: 344 NNALETLEASHF-PIDRLQELEISGN 368
+N+L T+ F L+ L++S N
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTN 191
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 89.8 bits (213), Expect = 2e-17
Identities = 61/197 (30%), Positives = 96/197 (48%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I +L + F S S++ L+L +N + + +DAF G +I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF L L+ LD S N+L + PE F L L+ L LR+NS+ IP LE+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDLS N ++ ++R+G L +L+ L L +N + ++ F L SL L L N ++ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 254 TSALSKLSNLSHLYLSG 270
L L L+G
Sbjct: 246 CGMEWTWGTLEKLDLTG 262
Score = 84.2 bits (199), Expect = 1e-15
Identities = 67/226 (29%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T ++L HN I + AF +L L +S NKI L + F +++L+LS N L
Sbjct: 86 QLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F D +LE LD S NRL + F L
Sbjct: 146 SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNI 224
L+ L L +N + I A+ + L L L N I ++ G+ + L+ LDL N
Sbjct: 206 KLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC-GMEWTWGTLEKLDLTGNE 264
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
I+++D F ++P+L+ L + +N + + + L+ L +L+ + LSG
Sbjct: 265 IKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Score = 55.2 bits (127), Expect = 6e-07
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+S N++ L F ++R L+L +N L +++ F+ +IS
Sbjct: 183 LEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKIS 242
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
N+ LE+LD + N + + FE + +LKIL + NN + + S L +
Sbjct: 243 NLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 302
Query: 191 LEYLDLSENL 200
L + LS NL
Sbjct: 303 LTTVGLSGNL 312
Score = 38.3 bits (85), Expect = 0.071
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 229 DQLGFHSLPSLRH-----LDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
D GFHS+P+ L L N++T + + S L+ L+L
Sbjct: 48 DSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQG 107
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + F INLQ + ++ N ++ + P LF+G KL ++++
Sbjct: 108 LYKLKELILSSNKIFY-LPNTTFTQLINLQNLDLSFN-QLSSLHPELFYGLRKLQTLHLR 165
Query: 344 NNALETLEASHF-PIDRLQELEISGN 368
+N+L T+ F L+ L++S N
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTN 191
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 89.8 bits (213), Expect = 2e-17
Identities = 61/197 (30%), Positives = 96/197 (48%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I +L + F S S++ L+L +N + + +DAF G +I +
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF L L+ LD S N+L + PE F L L+ L LR+NS+ IP LE+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDLS N ++ ++R+G L +L+ L L +N + ++ F L SL L L N ++ +
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 254 TSALSKLSNLSHLYLSG 270
L L L+G
Sbjct: 246 CGMEWTWGTLEKLDLTG 262
Score = 84.2 bits (199), Expect = 1e-15
Identities = 67/226 (29%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T ++L HN I + AF +L L +S NKI L + F +++L+LS N L
Sbjct: 86 QLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F D +LE LD S NRL + F L
Sbjct: 146 SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNI 224
L+ L L +N + I A+ + L L L N I ++ G+ + L+ LDL N
Sbjct: 206 KLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC-GMEWTWGTLEKLDLTGNE 264
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
I+++D F ++P+L+ L + +N + + + L+ L +L+ + LSG
Sbjct: 265 IKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 310
Score = 55.2 bits (127), Expect = 6e-07
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+S N++ L F ++R L+L +N L +++ F+ +IS
Sbjct: 183 LEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKIS 242
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
N+ LE+LD + N + + FE + +LKIL + NN + + S L +
Sbjct: 243 NLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 302
Query: 191 LEYLDLSENL 200
L + LS NL
Sbjct: 303 LTTVGLSGNL 312
Score = 38.3 bits (85), Expect = 0.071
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 229 DQLGFHSLPSLRH-----LDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
D GFHS+P+ L L N++T + + S L+ L+L
Sbjct: 48 DSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQG 107
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + F INLQ + ++ N ++ + P LF+G KL ++++
Sbjct: 108 LYKLKELILSSNKIFY-LPNTTFTQLINLQNLDLSFN-QLSSLHPELFYGLRKLQTLHLR 165
Query: 344 NNALETLEASHF-PIDRLQELEISGN 368
+N+L T+ F L+ L++S N
Sbjct: 166 SNSLRTIPVRLFWDCRSLEFLDLSTN 191
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 89.8 bits (213), Expect = 2e-17
Identities = 61/197 (30%), Positives = 96/197 (48%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + +N I +L + F S S++ L+L +N + + +DAF G +I +
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF L L+ LD S N+L + PE F L L+ L LR+NS+ IP LE+
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDLS N ++ ++R+G L +L+ L L +N + ++ F L SL L L N ++ +
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 254 TSALSKLSNLSHLYLSG 270
L L L+G
Sbjct: 259 CGMEWTWGTLEKLDLTG 275
Score = 84.2 bits (199), Expect = 1e-15
Identities = 67/226 (29%), Positives = 109/226 (48%), Gaps = 3/226 (1%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T ++L HN I + AF +L L +S NKI L + F +++L+LS N L
Sbjct: 99 QLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQL 158
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F D +LE LD S NRL + F L
Sbjct: 159 SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI 218
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL-KELKHLDLNNNI 224
L+ L L +N + I A+ + L L L N I ++ G+ + L+ LDL N
Sbjct: 219 KLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC-GMEWTWGTLEKLDLTGNE 277
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
I+++D F ++P+L+ L + +N + + + L+ L +L+ + LSG
Sbjct: 278 IKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSG 323
Score = 55.2 bits (127), Expect = 6e-07
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+S N++ L F ++R L+L +N L +++ F+ +IS
Sbjct: 196 LEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKIS 255
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
N+ LE+LD + N + + FE + +LKIL + NN + + S L +
Sbjct: 256 NLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 315
Query: 191 LEYLDLSENL 200
L + LS NL
Sbjct: 316 LTTVGLSGNL 325
Score = 38.3 bits (85), Expect = 0.071
Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 8/146 (5%)
Query: 229 DQLGFHSLPSLRH-----LDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
D GFHS+P+ L L N++T + + S L+ L+L
Sbjct: 61 DSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQG 120
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + F INLQ + ++ N ++ + P LF+G KL ++++
Sbjct: 121 LYKLKELILSSNKIFY-LPNTTFTQLINLQNLDLSFN-QLSSLHPELFYGLRKLQTLHLR 178
Query: 344 NNALETLEASHF-PIDRLQELEISGN 368
+N+L T+ F L+ L++S N
Sbjct: 179 SNSLRTIPVRLFWDCRSLEFLDLSTN 204
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 87.4 bits (207), Expect = 1e-16
Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 1/220 (0%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L+HNAI +L F L L + +N+I L +FE ++ L L +N L+ +
Sbjct: 294 VLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEV 353
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF+G + N+ Q FR L L L + L P TF LS L+
Sbjct: 354 KAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLR 413
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L++N ++ I +L + L LDL+ N + + L +L++L L+ N + +
Sbjct: 414 RLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 473
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L LD+S N + +P S L+ L L +L L
Sbjct: 474 PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Score = 86.6 bits (205), Expect = 2e-16
Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 3/306 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L L ++ N++ L F +E+R L+LS N L+ + + FV
Sbjct: 189 AFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLY 248
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
I+ + F L AL LD S+NR+ +TF L L++L L +N+I +
Sbjct: 249 LDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPR 308
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE L L N I+Q++ L +L+ L L++N ++ V F L ++ ++
Sbjct: 309 TFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMN 368
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
LS N + +P L L L+L G I+
Sbjct: 369 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLV-GIEE 427
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQE 362
++ L ++ + N ++ +P RLF G KL + + N L L A P+ R
Sbjct: 428 QSLWGLAELLELDLTSN-QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFW 486
Query: 363 LEISGN 368
L++S N
Sbjct: 487 LDVSHN 492
Score = 83.4 bits (197), Expect = 2e-15
Identities = 86/389 (22%), Positives = 162/389 (41%), Gaps = 20/389 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISY---NKILDLGSENFESNSEMRHLNLSNNFLKR 107
++L+ NA+ + N++ QL L Y N I + F +R L+LS+N +
Sbjct: 223 LDLSRNALRAI--KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
L +D F G I+++ +TF+DL LE L +NR+ +FE L L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L+L +N + ++ + + ++ ++LS N ++ + L +L L L + +
Sbjct: 341 EVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXX 287
+ F L LR L L DN + I +L L+ L L L+
Sbjct: 401 IRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKL 460
Query: 288 XXXXXXXXXXXERIDSRAFVDNINLQK-IWMN-DNVKVREVPPRLFHGNPKLTNIYMKNN 345
E + + A LQ+ W++ + ++ +P L +L + ++NN
Sbjct: 461 EYLLLSRNRLAE-LPADALGP---LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Query: 346 ALETLEASHFPIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKK------SGNSSEF 399
+L T ++RL + GNP+ C C L L + + + G+ +
Sbjct: 517 SLRTFTPQPPGLERLW---LEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQP 573
Query: 400 LKIDYEDVKCSGPLQLKGMLFVQIPESEF 428
Y ++ C+ P ++ G+ + E+ F
Sbjct: 574 PAYTYNNITCASPPEVVGLDLRDLSEAHF 602
Score = 73.3 bits (172), Expect = 2e-12
Identities = 81/358 (22%), Positives = 137/358 (38%), Gaps = 8/358 (2%)
Query: 17 CPVRCMC---DDALR-AASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQL 71
CP C+C DDA + C++ NL +P + + L N + ++ AF + L
Sbjct: 41 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSL 100
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L++ ++ L + + HL+L N L+ L F +S
Sbjct: 101 GFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR 160
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F L +L L+ N L F L SL+ L L N + + A + L
Sbjct: 161 LEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAEL 220
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
LDLS N ++ + + L L+ L L+ N+I +V F L +LR LDLS N +
Sbjct: 221 RELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ L L L LS ++ R+F + +
Sbjct: 281 LLEDTFPGLLGLRVLRLS-HNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF-EGLG 338
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
++ D+ +++EV F G + + + N L L F + +L L + G+
Sbjct: 339 QLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L HN + + AF T + V+++S N + +L + F ++ L+L + L R+
Sbjct: 342 VLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRI 401
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
F G + I Q+ L+ L LD ++N+L F+ L L+
Sbjct: 402 RPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLE 461
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
L L N + ++P+ LG + +LD+S N ++ + L L L++L L NN + +
Sbjct: 462 YLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRT 520
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 87.4 bits (207), Expect = 1e-16
Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 1/220 (0%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L+HNAI +L F L L + +N+I L +FE ++ L L +N L+ +
Sbjct: 294 VLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEV 353
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF+G + N+ Q FR L L L + L P TF LS L+
Sbjct: 354 KAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLR 413
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L++N ++ I +L + L LDL+ N + + L +L++L L+ N + +
Sbjct: 414 RLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 473
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L LD+S N + +P S L+ L L +L L
Sbjct: 474 PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Score = 87.0 bits (206), Expect = 2e-16
Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 3/306 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L L ++ N++ L F +E+R L+LS N L+ + + FV
Sbjct: 189 AFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLY 248
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
I+ + F L AL LD S+NR+ +TF L L++L L +N+I +
Sbjct: 249 LDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPR 308
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE L L N I+Q++ L +L+ L L++N ++ V F L ++ ++
Sbjct: 309 TFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMN 368
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
LS N + +P L L L+L G I+
Sbjct: 369 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLV-GIEE 427
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQE 362
++ L ++ + N ++ +P RLF G KL + + N L L A P+ R
Sbjct: 428 QSLWGLAELLELDLTSN-QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFW 486
Query: 363 LEISGN 368
L++S N
Sbjct: 487 LDVSHN 492
Score = 83.8 bits (198), Expect = 1e-15
Identities = 86/389 (22%), Positives = 162/389 (41%), Gaps = 20/389 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISY---NKILDLGSENFESNSEMRHLNLSNNFLKR 107
++L+ NA+ + N++ QL L Y N I + F +R L+LS+N +
Sbjct: 223 LDLSRNALRAI--KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
L +D F G I+++ +TF+DL LE L +NR+ +FE L L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L+L +N + ++ + + ++ ++LS N ++ + L +L L L + +
Sbjct: 341 EVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXX 287
+ F L LR L L DN + I +L L+ L L L+
Sbjct: 401 IRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKL 460
Query: 288 XXXXXXXXXXXERIDSRAFVDNINLQK-IWMN-DNVKVREVPPRLFHGNPKLTNIYMKNN 345
E + + A LQ+ W++ + ++ +P L +L + ++NN
Sbjct: 461 EYLLLSRNRLAE-LPADALGP---LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Query: 346 ALETLEASHFPIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKK------SGNSSEF 399
+L T ++RL + GNP+ C C L L + + + G+ +
Sbjct: 517 SLRTFTPQPPGLERLW---LEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQP 573
Query: 400 LKIDYEDVKCSGPLQLKGMLFVQIPESEF 428
Y ++ C+ P ++ G+ + E+ F
Sbjct: 574 PAYTYNNITCASPPEVVGLDLRDLSEAHF 602
Score = 73.7 bits (173), Expect = 2e-12
Identities = 81/358 (22%), Positives = 137/358 (38%), Gaps = 8/358 (2%)
Query: 17 CPVRCMC---DDALR-AASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQL 71
CP C+C DDA + C++ NL +P + + L N + ++ AF + L
Sbjct: 41 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSL 100
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L++ ++ L + + HL+L N L+ L F +S
Sbjct: 101 GFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR 160
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F L +L L+ N L F L SL+ L L N + + A + L
Sbjct: 161 LEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAEL 220
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
LDLS N ++ + + L L+ L L+ N+I +V F L +LR LDLS N +
Sbjct: 221 RELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ L L L LS ++ R+F + +
Sbjct: 281 LLEDTFPGLLGLRVLRLS-HNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF-EGLG 338
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
++ D+ +++EV F G + + + N L L F + +L L + G+
Sbjct: 339 QLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L HN + + AF T + V+++S N + +L + F ++ L+L + L R+
Sbjct: 342 VLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRI 401
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
F G + I Q+ L+ L LD ++N+L F+ L L+
Sbjct: 402 RPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLE 461
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
L L N + ++P+ LG + +LD+S N ++ + L L L++L L NN + +
Sbjct: 462 YLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRT 520
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 87.4 bits (207), Expect = 1e-16
Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 1/220 (0%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L+HNAI +L F L L + +N+I L +FE ++ L L +N L+ +
Sbjct: 294 VLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEV 353
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF+G + N+ Q FR L L L + L P TF LS L+
Sbjct: 354 KAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLR 413
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L++N ++ I +L + L LDL+ N + + L +L++L L+ N + +
Sbjct: 414 RLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 473
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L LD+S N + +P S L+ L L +L L
Sbjct: 474 PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Score = 86.6 bits (205), Expect = 2e-16
Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 3/306 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L L ++ N++ L F +E+R L+LS N L+ + + FV
Sbjct: 189 AFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLY 248
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
I+ + F L AL LD S+NR+ +TF L L++L L +N+I +
Sbjct: 249 LDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPR 308
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE L L N I+Q++ L +L+ L L++N ++ V F L ++ ++
Sbjct: 309 TFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMN 368
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
LS N + +P L L L+L G I+
Sbjct: 369 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLV-GIEE 427
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQE 362
++ L ++ + N ++ +P RLF G KL + + N L L A P+ R
Sbjct: 428 QSLWGLAELLELDLTSN-QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFW 486
Query: 363 LEISGN 368
L++S N
Sbjct: 487 LDVSHN 492
Score = 83.4 bits (197), Expect = 2e-15
Identities = 86/389 (22%), Positives = 162/389 (41%), Gaps = 20/389 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISY---NKILDLGSENFESNSEMRHLNLSNNFLKR 107
++L+ NA+ + N++ QL L Y N I + F +R L+LS+N +
Sbjct: 223 LDLSRNALRAI--KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
L +D F G I+++ +TF+DL LE L +NR+ +FE L L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L+L +N + ++ + + ++ ++LS N ++ + L +L L L + +
Sbjct: 341 EVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXX 287
+ F L LR L L DN + I +L L+ L L L+
Sbjct: 401 IRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKL 460
Query: 288 XXXXXXXXXXXERIDSRAFVDNINLQK-IWMN-DNVKVREVPPRLFHGNPKLTNIYMKNN 345
E + + A LQ+ W++ + ++ +P L +L + ++NN
Sbjct: 461 EYLLLSRNRLAE-LPADALGP---LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Query: 346 ALETLEASHFPIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKK------SGNSSEF 399
+L T ++RL + GNP+ C C L L + + + G+ +
Sbjct: 517 SLRTFTPQPPGLERLW---LEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQP 573
Query: 400 LKIDYEDVKCSGPLQLKGMLFVQIPESEF 428
Y ++ C+ P ++ G+ + E+ F
Sbjct: 574 PAYTYNNITCASPPEVVGLDLRDLSEAHF 602
Score = 73.3 bits (172), Expect = 2e-12
Identities = 81/358 (22%), Positives = 137/358 (38%), Gaps = 8/358 (2%)
Query: 17 CPVRCMC---DDALR-AASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQL 71
CP C+C DDA + C++ NL +P + + L N + ++ AF + L
Sbjct: 41 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSL 100
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L++ ++ L + + HL+L N L+ L F +S
Sbjct: 101 GFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR 160
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F L +L L+ N L F L SL+ L L N + + A + L
Sbjct: 161 LEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAEL 220
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
LDLS N ++ + + L L+ L L+ N+I +V F L +LR LDLS N +
Sbjct: 221 RELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ L L L LS ++ R+F + +
Sbjct: 281 LLEDTFPGLLGLRVLRLS-HNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF-EGLG 338
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
++ D+ +++EV F G + + + N L L F + +L L + G+
Sbjct: 339 QLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L HN + + AF T + V+++S N + +L + F ++ L+L + L R+
Sbjct: 342 VLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRI 401
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
F G + I Q+ L+ L LD ++N+L F+ L L+
Sbjct: 402 RPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLE 461
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
L L N + ++P+ LG + +LD+S N ++ + L L L++L L NN + +
Sbjct: 462 YLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRT 520
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 87.4 bits (207), Expect = 1e-16
Identities = 62/220 (28%), Positives = 100/220 (45%), Gaps = 1/220 (0%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L+HNAI +L F L L + +N+I L +FE ++ L L +N L+ +
Sbjct: 294 VLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEV 353
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF+G + N+ Q FR L L L + L P TF LS L+
Sbjct: 354 KAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLR 413
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L++N ++ I +L + L LDL+ N + + L +L++L L+ N + +
Sbjct: 414 RLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAEL 473
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L LD+S N + +P S L+ L L +L L
Sbjct: 474 PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSL 513
Score = 86.6 bits (205), Expect = 2e-16
Identities = 77/306 (25%), Positives = 128/306 (41%), Gaps = 3/306 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L L ++ N++ L F +E+R L+LS N L+ + + FV
Sbjct: 189 AFRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLY 248
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
I+ + F L AL LD S+NR+ +TF L L++L L +N+I +
Sbjct: 249 LDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPR 308
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE L L N I+Q++ L +L+ L L++N ++ V F L ++ ++
Sbjct: 309 TFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMN 368
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
LS N + +P L L L+L G I+
Sbjct: 369 LSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLV-GIEE 427
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQE 362
++ L ++ + N ++ +P RLF G KL + + N L L A P+ R
Sbjct: 428 QSLWGLAELLELDLTSN-QLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFW 486
Query: 363 LEISGN 368
L++S N
Sbjct: 487 LDVSHN 492
Score = 83.4 bits (197), Expect = 2e-15
Identities = 86/389 (22%), Positives = 162/389 (41%), Gaps = 20/389 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISY---NKILDLGSENFESNSEMRHLNLSNNFLKR 107
++L+ NA+ + N++ QL L Y N I + F +R L+LS+N +
Sbjct: 223 LDLSRNALRAI--KANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
L +D F G I+++ +TF+DL LE L +NR+ +FE L L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L+L +N + ++ + + ++ ++LS N ++ + L +L L L + +
Sbjct: 341 EVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGR 400
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXX 287
+ F L LR L L DN + I +L L+ L L L+
Sbjct: 401 IRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKL 460
Query: 288 XXXXXXXXXXXERIDSRAFVDNINLQK-IWMN-DNVKVREVPPRLFHGNPKLTNIYMKNN 345
E + + A LQ+ W++ + ++ +P L +L + ++NN
Sbjct: 461 EYLLLSRNRLAE-LPADALGP---LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
Query: 346 ALETLEASHFPIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKK------SGNSSEF 399
+L T ++RL + GNP+ C C L L + + + G+ +
Sbjct: 517 SLRTFTPQPPGLERLW---LEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQP 573
Query: 400 LKIDYEDVKCSGPLQLKGMLFVQIPESEF 428
Y ++ C+ P ++ G+ + E+ F
Sbjct: 574 PAYTYNNITCASPPEVVGLDLRDLSEAHF 602
Score = 73.3 bits (172), Expect = 2e-12
Identities = 81/358 (22%), Positives = 137/358 (38%), Gaps = 8/358 (2%)
Query: 17 CPVRCMC---DDALR-AASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQL 71
CP C+C DDA + C++ NL +P + + L N + ++ AF + L
Sbjct: 41 CPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSL 100
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L++ ++ L + + HL+L N L+ L F +S
Sbjct: 101 GFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSR 160
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F L +L L+ N L F L SL+ L L N + + A + L
Sbjct: 161 LEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLAEL 220
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
LDLS N ++ + + L L+ L L+ N+I +V F L +LR LDLS N +
Sbjct: 221 RELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAG 280
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ L L L LS ++ R+F + +
Sbjct: 281 LLEDTFPGLLGLRVLRLS-HNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSF-EGLG 338
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
++ D+ +++EV F G + + + N L L F + +L L + G+
Sbjct: 339 QLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGS 396
Score = 66.5 bits (155), Expect = 2e-10
Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L HN + + AF T + V+++S N + +L + F ++ L+L + L R+
Sbjct: 342 VLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRI 401
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
F G + I Q+ L+ L LD ++N+L F+ L L+
Sbjct: 402 RPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLE 461
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
L L N + ++P+ LG + +LD+S N ++ + L L L++L L NN + +
Sbjct: 462 YLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLRT 520
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 86.6 bits (205), Expect = 2e-16
Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 5/261 (1%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLY 68
+ AA LC C CD R C+ L VP L+ ++++ N I L AF +
Sbjct: 22 SGAAPPLCAAPCSCDGD-RRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF 80
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
L L ++ N + + + E++ L L NN LK + +A G
Sbjct: 81 PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANH 140
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+++ +F L L L +N L L +L+ L+L N I IP +
Sbjct: 141 ITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNL 200
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L N I+ +S+H L L+ LDL+ N + Q + PSL+ L N+
Sbjct: 201 SSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQ-AIKARPSLKELGFHSNS 259
Query: 249 MTLIPTSAL--SKLSNLSHLY 267
+++IP A + L HLY
Sbjct: 260 ISVIPDGAFDGNPLLRTIHLY 280
Score = 74.5 bits (175), Expect = 9e-13
Identities = 53/172 (30%), Positives = 79/172 (45%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L++S N + +L +DAF ++S IH + L L+ L NN+L T
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
E LS+L+ L L N I +P + ++ L +L L +N + +V H L L L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L N I S+ F +L SL L L +N + + L NL L LS
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLS 233
Score = 66.9 bits (156), Expect = 2e-10
Identities = 56/216 (25%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L++N + A L L N I + F+ N +R ++L +N L +
Sbjct: 230 LDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 289
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + VQ F +L+ LE L + ++ + + L
Sbjct: 290 SAFHNLSDLHSLVIRGASM----VQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKML 345
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N+I D+PS N LE + L N I Q+ L L+ LDL+ N+I
Sbjct: 346 RTLDLSYNNIRDLPSFNGCHA--LEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHE 403
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ F +L + +LD+S N +T PT L+ L+ L
Sbjct: 404 IHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL 439
Score = 62.5 bits (145), Expect = 4e-09
Identities = 44/131 (33%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Query: 140 LSAL-ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
LSA + LD S N + + F+ L+ L L N + I L + L+ L L
Sbjct: 55 LSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQN 114
Query: 199 NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
N ++ V + L L+ L L+ N I SV + F L LRHL L DN++T +P LS
Sbjct: 115 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 174
Query: 259 KLSNLSHLYLS 269
L L L L+
Sbjct: 175 NLPTLQALTLA 185
Score = 53.2 bits (122), Expect = 2e-06
Identities = 59/222 (26%), Positives = 98/222 (44%), Gaps = 7/222 (3%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I L + F+ L LD+SYN + + + ++ ++ L +N + +
Sbjct: 205 VLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSISVI 263
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF G +S + F +LS L L +V P + L+
Sbjct: 264 PDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LE 322
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV-SRHGLPFLKELKHLDLNNNIIES 227
L+L I IP+ L LDLS N I+ + S +G L+E+ L N I
Sbjct: 323 SLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEIS---LQRNQIYQ 379
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + F L SLR LDLS N + I + A + L +++L +S
Sbjct: 380 IKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVS 421
Score = 48.4 bits (110), Expect = 7e-05
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+SYN I DL S F + ++L N + ++ + F G I
Sbjct: 345 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
IH + F L + LD S N L +F E L+ LK++
Sbjct: 403 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLV 442
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 3/177 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L + + N + +G+ F + S++ L + + + + G
Sbjct: 267 AFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPN-LTGTVHLESLT 325
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
+IS+I ++ L LD S N + +F +L+ +SL+ N I I
Sbjct: 326 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEG 383
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
+I L LDLS NLI ++ L + +LD++ N + S G + L L+
Sbjct: 384 TFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLK 440
Score = 42.7 bits (96), Expect = 0.003
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
+F ALE + N++ + TF+ L SL+IL L N I +I S + + LD
Sbjct: 360 SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLD 419
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+S N + GL L +LK L N + E++ F +L SL
Sbjct: 420 VSFNELTSFPTEGLNGLNQLK-LVGNFKLKEALAAKDFVNLRSL 462
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 86.6 bits (205), Expect = 2e-16
Identities = 71/261 (27%), Positives = 110/261 (42%), Gaps = 5/261 (1%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLY 68
+ AA LC C CD R C+ L VP L+ ++++ N I L AF +
Sbjct: 22 SGAAPPLCAAPCSCDGD-RRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF 80
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
L L ++ N + + + E++ L L NN LK + +A G
Sbjct: 81 PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANH 140
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+++ +F L L L +N L L +L+ L+L N I IP +
Sbjct: 141 ITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNL 200
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L N I+ +S+H L L+ LDL+ N + Q + PSL+ L N+
Sbjct: 201 SSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQ-AIKARPSLKELGFHSNS 259
Query: 249 MTLIPTSAL--SKLSNLSHLY 267
+++IP A + L HLY
Sbjct: 260 ISVIPDGAFDGNPLLRTIHLY 280
Score = 74.5 bits (175), Expect = 9e-13
Identities = 53/172 (30%), Positives = 79/172 (45%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L++S N + +L +DAF ++S IH + L L+ L NN+L T
Sbjct: 62 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 121
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
E LS+L+ L L N I +P + ++ L +L L +N + +V H L L L+
Sbjct: 122 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 181
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L N I S+ F +L SL L L +N + + L NL L LS
Sbjct: 182 LTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLS 233
Score = 62.5 bits (145), Expect = 4e-09
Identities = 44/131 (33%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Query: 140 LSAL-ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
LSA + LD S N + + F+ L+ L L N + I L + L+ L L
Sbjct: 55 LSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQN 114
Query: 199 NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
N ++ V + L L+ L L+ N I SV + F L LRHL L DN++T +P LS
Sbjct: 115 NQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLS 174
Query: 259 KLSNLSHLYLS 269
L L L L+
Sbjct: 175 NLPTLQALTLA 185
Score = 60.9 bits (141), Expect = 1e-08
Identities = 54/216 (25%), Positives = 90/216 (41%), Gaps = 9/216 (4%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L++N + A L L N I + F+ N +R ++L +N L +
Sbjct: 230 LDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 289
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
A + VQ F +L+ LE L + ++ + + L
Sbjct: 290 SASHNLSDLHSLVIRGASM----VQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKML 345
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N+I D+PS N LE + L N I Q+ L L+ LDL+ N+I
Sbjct: 346 RTLDLSYNNIRDLPSFNGCHA--LEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHE 403
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ F +L + +LD+S N +T PT + L+ L
Sbjct: 404 IHSRAFATLGPITNLDVSFNELTSFPTEGPNGLNQL 439
Score = 50.0 bits (114), Expect = 2e-05
Identities = 58/222 (26%), Positives = 97/222 (43%), Gaps = 7/222 (3%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I L + F+ L LD+SYN + + + ++ ++ L +N + +
Sbjct: 205 VLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEF-PQAIKARPSLKELGFHSNSISVI 263
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF G +S + +LS L L +V P + L+
Sbjct: 264 PDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQQFPNLTGTVH-LE 322
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV-SRHGLPFLKELKHLDLNNNIIES 227
L+L I IP+ L LDLS N I+ + S +G L+E+ L N I
Sbjct: 323 SLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEIS---LQRNQIYQ 379
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + F L SLR LDLS N + I + A + L +++L +S
Sbjct: 380 IKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVS 421
Score = 46.8 bits (106), Expect = 2e-04
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+SYN I DL S F + ++L N + ++ + F G I
Sbjct: 345 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 402
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
IH + F L + LD S N L +F E L+ LK++
Sbjct: 403 EIHSRAFATLGPITNLDVSFNELTSFPTEGPNGLNQLKLV 442
Score = 44.0 bits (99), Expect = 0.001
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 2/113 (1%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+IS+I ++ L LD S N + +F +L+ +SL+ N I I
Sbjct: 330 KISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEGTFQG 387
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
+I L LDLS NLI ++ L + +LD++ N + S G + L L+
Sbjct: 388 LISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGPNGLNQLK 440
>M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein
protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.8 bits (203), Expect = 4e-16
Identities = 61/197 (30%), Positives = 94/197 (47%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN + L F+ +++ L L +N + +D++AF G IS
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TFR ++ L LD S N+L + E F L L L LR+NS+ IP +LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+ ++R+ + LK L L +N ++ F L SL++L L N +++I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 254 TSALSKLSNLSHLYLSG 270
+ S+L L LSG
Sbjct: 246 QTMSWTWSSLQRLDLSG 262
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/226 (28%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Query: 47 EATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I N+ AFN +L L +S N+I + F + +R+L+LS N L
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F+D LE LD NR+ + F +
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
LK L L +N + A ++ L+ L L N I + + L+ LDL+ N I
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 226 ESVDQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E+ F +P+L+ L+L N +T I L +L+ + L+G
Sbjct: 266 EAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311
Score = 77.4 bits (182), Expect = 1e-13
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 4/260 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
++A+ CP C C+ + C + L+ +P ++ ++L +N++ L Y F
Sbjct: 28 SSAERGCPKGCRCEGKM--VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
QLT L + +N I ++ F ++ L LS+N + + F ++
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
++ + FR L L L +N L T F+ +L++L L N I + +I
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L L N +++ P L L++L L N I + Q + SL+ LDLS N +
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 250 TLIP-TSALSKLSNLSHLYL 268
S + NL L L
Sbjct: 266 EAFSGPSVFQCVPNLQRLNL 285
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.8 bits (203), Expect = 4e-16
Identities = 61/197 (30%), Positives = 94/197 (47%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN + L F+ +++ L L +N + +D++AF G IS
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TFR ++ L LD S N+L + E F L L L LR+NS+ IP +LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+ ++R+ + LK L L +N ++ F L SL++L L N +++I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 254 TSALSKLSNLSHLYLSG 270
+ S+L L LSG
Sbjct: 246 QTMSWTWSSLQRLDLSG 262
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/226 (28%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Query: 47 EATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I N+ AFN +L L +S N+I + F + +R+L+LS N L
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F+D LE LD NR+ + F +
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
LK L L +N + A ++ L+ L L N I + + L+ LDL+ N I
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 226 ESVDQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E+ F +P+L+ L+L N +T I L +L+ + L+G
Sbjct: 266 EAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311
Score = 77.4 bits (182), Expect = 1e-13
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 4/260 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
++A+ CP C C+ + C + L+ +P ++ ++L +N++ L Y F
Sbjct: 28 SSAERGCPKGCRCEGKM--VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
QLT L + +N I ++ F ++ L LS+N + + F ++
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
++ + FR L L L +N L T F+ +L++L L N I + +I
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L L N +++ P L L++L L N I + Q + SL+ LDLS N +
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 250 TLIP-TSALSKLSNLSHLYL 268
S + NL L L
Sbjct: 266 EAFSGPSVFQCVPNLQRLNL 285
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 85.8 bits (203), Expect = 4e-16
Identities = 61/197 (30%), Positives = 94/197 (47%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN + L F+ +++ L L +N + +D++AF G IS
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TFR ++ L LD S N+L + E F L L L LR+NS+ IP +LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+ ++R+ + LK L L +N ++ F L SL++L L N +++I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 254 TSALSKLSNLSHLYLSG 270
+ S+L L LSG
Sbjct: 246 QTMSWTWSSLQRLDLSG 262
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/226 (28%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Query: 47 EATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I N+ AFN +L L +S N+I + F + +R+L+LS N L
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F+D LE LD NR+ + F +
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
LK L L +N + A ++ L+ L L N I + + L+ LDL+ N I
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 226 ESVDQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E+ F +P+L+ L+L N +T I L +L+ + L+G
Sbjct: 266 EAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311
Score = 77.4 bits (182), Expect = 1e-13
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 4/260 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
++A+ CP C C+ + C + L+ +P ++ ++L +N++ L Y F
Sbjct: 28 SSAERGCPKGCRCEGKM--VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
QLT L + +N I ++ F ++ L LS+N + + F ++
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
++ + FR L L L +N L T F+ +L++L L N I + +I
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L L N +++ P L L++L L N I + Q + SL+ LDLS N +
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 250 TLIP-TSALSKLSNLSHLYL 268
S + NL L L
Sbjct: 266 EAFSGPSVFQCVPNLQRLNL 285
>BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 85.8 bits (203), Expect = 4e-16
Identities = 61/197 (30%), Positives = 94/197 (47%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN + L F+ +++ L L +N + +D++AF G IS
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TFR ++ L LD S N+L + E F L L L LR+NS+ IP +LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+ ++R+ + LK L L +N ++ F L SL++L L N +++I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 254 TSALSKLSNLSHLYLSG 270
+ S+L L LSG
Sbjct: 246 QTMSWTWSSLQRLDLSG 262
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/226 (28%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Query: 47 EATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I N+ AFN +L L +S N+I + F + +R+L+LS N L
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F+D LE LD NR+ + F +
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
LK L L +N + A ++ L+ L L N I + + L+ LDL+ N I
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 226 ESVDQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E+ F +P+L+ L+L N +T I L +L+ + L+G
Sbjct: 266 EAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311
Score = 77.4 bits (182), Expect = 1e-13
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 4/260 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
++A+ CP C C+ + C + L+ +P ++ ++L +N++ L Y F
Sbjct: 28 SSAERGCPKGCRCEGKM--VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
QLT L + +N I ++ F ++ L LS+N + + F ++
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
++ + FR L L L +N L T F+ +L++L L N I + +I
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L L N +++ P L L++L L N I + Q + SL+ LDLS N +
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 250 TLIP-TSALSKLSNLSHLYL 268
S + NL L L
Sbjct: 266 EAFSGPSVFQCVPNLQRLNL 285
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 85.8 bits (203), Expect = 4e-16
Identities = 61/197 (30%), Positives = 94/197 (47%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + YN + L F+ +++ L L +N + +D++AF G IS
Sbjct: 66 LSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFL 125
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TFR ++ L LD S N+L + E F L L L LR+NS+ IP +LE
Sbjct: 126 NNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLEL 185
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+ ++R+ + LK L L +N ++ F L SL++L L N +++I
Sbjct: 186 LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIG 245
Query: 254 TSALSKLSNLSHLYLSG 270
+ S+L L LSG
Sbjct: 246 QTMSWTWSSLQRLDLSG 262
Score = 82.6 bits (195), Expect = 3e-15
Identities = 65/226 (28%), Positives = 102/226 (45%), Gaps = 2/226 (0%)
Query: 47 EATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I N+ AFN +L L +S N+I + F + +R+L+LS N L
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
L + F G + I V+ F+D LE LD NR+ + F +
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
LK L L +N + A ++ L+ L L N I + + L+ LDL+ N I
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 226 ESVDQLG-FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E+ F +P+L+ L+L N +T I L +L+ + L+G
Sbjct: 266 EAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311
Score = 77.4 bits (182), Expect = 1e-13
Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 4/260 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
++A+ CP C C+ + C + L+ +P ++ ++L +N++ L Y F
Sbjct: 28 SSAERGCPKGCRCEGKM--VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLN 85
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
QLT L + +N I ++ F ++ L LS+N + + F ++
Sbjct: 86 QLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQL 145
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
++ + FR L L L +N L T F+ +L++L L N I + +I
Sbjct: 146 HSLGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMI 205
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L L N +++ P L L++L L N I + Q + SL+ LDLS N +
Sbjct: 206 RLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI 265
Query: 250 TLIP-TSALSKLSNLSHLYL 268
S + NL L L
Sbjct: 266 EAFSGPSVFQCVPNLQRLNL 285
>AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein.
Length = 359
Score = 85.8 bits (203), Expect = 4e-16
Identities = 72/256 (28%), Positives = 110/256 (42%), Gaps = 12/256 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Query: 253 PTSALSKLSNLSHLYL 268
P L++ + +YL
Sbjct: 285 P-GGLAEHKYIQVVYL 299
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 1/202 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHLY 267
NN+ PT A+ LSNL L+
Sbjct: 243 YNNLDEFPT-AIRTLSNLKELH 263
Score = 73.7 bits (173), Expect = 2e-12
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSSL +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L +N I+ V + F LP LR L
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLT 287
Query: 244 LSD-NNMTLIPTSALSKLSNLSHLYLSG 270
L+ + +T P L+ +NL L L+G
Sbjct: 288 LNGASQITEFPD--LTGTANLESLTLTG 313
Score = 64.5 bits (150), Expect = 1e-09
Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 5/220 (2%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
M L N I ++ YAF + L VL + N+I LG + F+ + L+L+ N L
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF- 249
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
A I + F+ L L L + +T P+ ++L+
Sbjct: 250 PTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLES 308
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L+L I +P + +L+ LDLS NL++ + + ++L+ +DL +N I +
Sbjct: 309 LTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIK 366
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
F L SLR L+L+ N + +I +A S L +L L LS
Sbjct: 367 VDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLS 406
Score = 63.7 bits (148), Expect = 2e-09
Identities = 45/140 (32%), Positives = 66/140 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ IP A LS+L L+L
Sbjct: 198 IHHIPDYAFGNLSSLVVLHL 217
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 59.3 bits (137), Expect = 4e-08
Identities = 59/225 (26%), Positives = 103/225 (45%), Gaps = 14/225 (6%)
Query: 50 LMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I +L F+ L LD++YN LD + S ++ L+ +N ++ +
Sbjct: 214 VLHLHNNRIHSLGKKCFDGLHSLETLDLNYNN-LDEFPTAIRTLSNLKELHFYDNPIQFV 272
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLS 165
+ AF + F DL+ LE L + ++ + L
Sbjct: 273 GRSAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLP 328
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
+L++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 329 NLQVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKI 386
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 387 AIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 428
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/191 (27%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L+ L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F L +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
Score = 54.4 bits (125), Expect = 1e-06
Identities = 59/238 (24%), Positives = 94/238 (39%), Gaps = 7/238 (2%)
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNS-ILDIPSANLGFVIHL 191
H D L R+D S+ L P +S LS+ N S +L P +L F L
Sbjct: 37 HCHCEPDGRMLLRVDCSDLGLSEL-PSNLSVFTSYLDLSMNNISQLLPNPLPSLRF---L 92
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
E L L+ N + + + L LK L L NN + V +L SL+ L L N+++
Sbjct: 93 EELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISY 152
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+P S S L +L HL+L I AF + +
Sbjct: 153 VPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI-HHIPDYAFGNLSS 211
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGNP 369
L + +++N ++ + + F G L + + N L+ + + L+EL NP
Sbjct: 212 LVVLHLHNN-RIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 84.2 bits (199), Expect = 1e-15
Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 1/202 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHLY 267
NN+ PT A+ LSNL L+
Sbjct: 243 YNNLDEFPT-AIRTLSNLKELH 263
Score = 73.7 bits (173), Expect = 2e-12
Identities = 60/208 (28%), Positives = 94/208 (45%), Gaps = 4/208 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSSL +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L +N I+ V + F LP LR L
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLT 287
Query: 244 LSD-NNMTLIPTSALSKLSNLSHLYLSG 270
L+ + +T P L+ +NL L L+G
Sbjct: 288 LNGASQITEFPD--LTGTANLESLTLTG 313
Score = 64.5 bits (150), Expect = 1e-09
Identities = 60/220 (27%), Positives = 99/220 (45%), Gaps = 5/220 (2%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
M L N I ++ YAF + L VL + N+I LG + F+ + L+L+ N L
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEF- 249
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
A I + F+ L L L + +T P+ ++L+
Sbjct: 250 PTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPD-LTGTANLES 308
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L+L I +P + +L+ LDLS NL++ + + ++L+ +DL +N I +
Sbjct: 309 LTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIK 366
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
F L SLR L+L+ N + +I +A S L +L L LS
Sbjct: 367 VDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLS 406
Score = 63.7 bits (148), Expect = 2e-09
Identities = 45/140 (32%), Positives = 66/140 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ IP A LS+L L+L
Sbjct: 198 IHHIPDYAFGNLSSLVVLHL 217
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 59.3 bits (137), Expect = 4e-08
Identities = 59/225 (26%), Positives = 103/225 (45%), Gaps = 14/225 (6%)
Query: 50 LMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I +L F+ L LD++YN LD + S ++ L+ +N ++ +
Sbjct: 214 VLHLHNNRIHSLGKKCFDGLHSLETLDLNYNN-LDEFPTAIRTLSNLKELHFYDNPIQFV 272
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLS 165
+ AF + F DL+ LE L + ++ + L
Sbjct: 273 GRSAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLP 328
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
+L++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 329 NLQVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKI 386
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 387 AIIHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 428
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/191 (27%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L+ L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F L +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
Score = 54.4 bits (125), Expect = 1e-06
Identities = 59/238 (24%), Positives = 94/238 (39%), Gaps = 7/238 (2%)
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNS-ILDIPSANLGFVIHL 191
H D L R+D S+ L P +S LS+ N S +L P +L F L
Sbjct: 37 HCHCEPDGRMLLRVDCSDLGLSEL-PSNLSVFTSYLDLSMNNISQLLPNPLPSLRF---L 92
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
E L L+ N + + + L LK L L NN + V +L SL+ L L N+++
Sbjct: 93 EELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISY 152
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+P S S L +L HL+L I AF + +
Sbjct: 153 VPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKI-HHIPDYAFGNLSS 211
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGNP 369
L + +++N ++ + + F G L + + N L+ + + L+EL NP
Sbjct: 212 LVVLHLHNN-RIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/225 (28%), Positives = 107/225 (47%), Gaps = 2/225 (0%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I ++ AF ++ L +S N+I L + F +R ++LS N L
Sbjct: 90 QLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKL 149
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
+ L D F G I + V+ F+D +L+ LD N+L + +F L
Sbjct: 150 QALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLF 209
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
L L L +N ++ + A+ +I L L L N + V L ++ L+ +DL+ N I
Sbjct: 210 KLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVV-SSLDWVWNLEKMDLSGNEI 268
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E ++ F ++P L+ L L N +T I L+ +L+ + L+G
Sbjct: 269 EYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL A + + L L + YN + +L + F ++ L L +N + + DAF
Sbjct: 56 NLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRV 115
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
+I+ + TFR + L +D S N+L P+ F L L L +R N+I
Sbjct: 116 KELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQF 175
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P L++LD+ N ++ ++R+ L +L L L +N + V+ F L SL
Sbjct: 176 VPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISL 235
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L N + ++ S+L + NL + LSG
Sbjct: 236 HSLCLRRNKVAIV-VSSLDWVWNLEKMDLSG 265
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 9/210 (4%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + ++ L +L L L++N I SV F L ++ L LS N +T +P
Sbjct: 70 LSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLP 129
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
+ + NL + LS + + R F D +L+
Sbjct: 130 NTTFRPMPNLRSVDLS-YNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLK 188
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFAC 372
+ + N +++ + F G KLT +++++N L + +HFP + L L + N A
Sbjct: 189 FLDIGYN-QLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAI 247
Query: 373 NCSLL-WLWKLGKDSETTTKKSGNSSEFLK 401
S L W+W L K SGN E+++
Sbjct: 248 VVSSLDWVWNLEK-----MDLSGNEIEYME 272
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
T +++ NAI + + F L LDI YN++ L +F ++ L+L +N L +
Sbjct: 164 TTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVK 223
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
++ F +++ I V + + LE++D S N + EP FE + L
Sbjct: 224 VNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHL 282
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+ L L +N + I L L + L+ NL
Sbjct: 283 QSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
Score = 36.3 bits (80), Expect = 0.29
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 3/136 (2%)
Query: 234 HSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
H+L L L L N+++ + + L L+ LYL
Sbjct: 62 HNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLS 121
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
+ + + F NL+ + ++ N K++ + P LFHG KLT ++M+ NA++ +
Sbjct: 122 SNQITQ-LPNTTFRPMPNLRSVDLSYN-KLQALAPDLFHGLRKLTTLHMRANAIQFVPVR 179
Query: 354 HFPIDR-LQELEISGN 368
F R L+ L+I N
Sbjct: 180 IFQDCRSLKFLDIGYN 195
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/225 (28%), Positives = 107/225 (47%), Gaps = 2/225 (0%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I ++ AF ++ L +S N+I L + F +R ++LS N L
Sbjct: 90 QLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKL 149
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
+ L D F G I + V+ F+D +L+ LD N+L + +F L
Sbjct: 150 QALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLF 209
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
L L L +N ++ + A+ +I L L L N + V L ++ L+ +DL+ N I
Sbjct: 210 KLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVV-SSLDWVWNLEKMDLSGNEI 268
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E ++ F ++P L+ L L N +T I L+ +L+ + L+G
Sbjct: 269 EYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL A + + L L + YN + +L + F ++ L L +N + + DAF
Sbjct: 56 NLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRV 115
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
+I+ + TFR + L +D S N+L P+ F L L L +R N+I
Sbjct: 116 KELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQF 175
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P L++LD+ N ++ ++R+ L +L L L +N + V+ F L SL
Sbjct: 176 VPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISL 235
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L N + ++ S+L + NL + LSG
Sbjct: 236 HSLCLRRNKVAIV-VSSLDWVWNLEKMDLSG 265
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 9/210 (4%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + ++ L +L L L++N I SV F L ++ L LS N +T +P
Sbjct: 70 LSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLP 129
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
+ + NL + LS + + R F D +L+
Sbjct: 130 NTTFRPMPNLRSVDLS-YNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLK 188
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFAC 372
+ + N +++ + F G KLT +++++N L + +HFP + L L + N A
Sbjct: 189 FLDIGYN-QLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAI 247
Query: 373 NCSLL-WLWKLGKDSETTTKKSGNSSEFLK 401
S L W+W L K SGN E+++
Sbjct: 248 VVSSLDWVWNLEK-----MDLSGNEIEYME 272
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
T +++ NAI + + F L LDI YN++ L +F ++ L+L +N L +
Sbjct: 164 TTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVK 223
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
++ F +++ I V + + LE++D S N + EP FE + L
Sbjct: 224 VNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHL 282
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+ L L +N + I L L + L+ NL
Sbjct: 283 QSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
Score = 36.3 bits (80), Expect = 0.29
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 3/136 (2%)
Query: 234 HSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
H+L L L L N+++ + + L L+ LYL
Sbjct: 62 HNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLS 121
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
+ + + F NL+ + ++ N K++ + P LFHG KLT ++M+ NA++ +
Sbjct: 122 SNQITQ-LPNTTFRPMPNLRSVDLSYN-KLQALAPDLFHGLRKLTTLHMRANAIQFVPVR 179
Query: 354 HFPIDR-LQELEISGN 368
F R L+ L+I N
Sbjct: 180 IFQDCRSLKFLDIGYN 195
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/225 (28%), Positives = 107/225 (47%), Gaps = 2/225 (0%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I ++ AF ++ L +S N+I L + F +R ++LS N L
Sbjct: 90 QLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKL 149
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
+ L D F G I + V+ F+D +L+ LD N+L + +F L
Sbjct: 150 QALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLF 209
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
L L L +N ++ + A+ +I L L L N + V L ++ L+ +DL+ N I
Sbjct: 210 KLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVV-SSLDWVWNLEKMDLSGNEI 268
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E ++ F ++P L+ L L N +T I L+ +L+ + L+G
Sbjct: 269 EYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL A + + L L + YN + +L + F ++ L L +N + + DAF
Sbjct: 56 NLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRV 115
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
+I+ + TFR + L +D S N+L P+ F L L L +R N+I
Sbjct: 116 KELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQF 175
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P L++LD+ N ++ ++R+ L +L L L +N + V+ F L SL
Sbjct: 176 VPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISL 235
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L N + ++ S+L + NL + LSG
Sbjct: 236 HSLCLRRNKVAIV-VSSLDWVWNLEKMDLSG 265
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 9/210 (4%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + ++ L +L L L++N I SV F L ++ L LS N +T +P
Sbjct: 70 LSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLP 129
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
+ + NL + LS + + R F D +L+
Sbjct: 130 NTTFRPMPNLRSVDLS-YNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLK 188
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFAC 372
+ + N +++ + F G KLT +++++N L + +HFP + L L + N A
Sbjct: 189 FLDIGYN-QLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAI 247
Query: 373 NCSLL-WLWKLGKDSETTTKKSGNSSEFLK 401
S L W+W L K SGN E+++
Sbjct: 248 VVSSLDWVWNLEK-----MDLSGNEIEYME 272
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
T +++ NAI + + F L LDI YN++ L +F ++ L+L +N L +
Sbjct: 164 TTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVK 223
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
++ F +++ I V + + LE++D S N + EP FE + L
Sbjct: 224 VNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHL 282
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+ L L +N + I L L + L+ NL
Sbjct: 283 QSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
Score = 36.3 bits (80), Expect = 0.29
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 3/136 (2%)
Query: 234 HSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
H+L L L L N+++ + + L L+ LYL
Sbjct: 62 HNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLS 121
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
+ + + F NL+ + ++ N K++ + P LFHG KLT ++M+ NA++ +
Sbjct: 122 SNQITQ-LPNTTFRPMPNLRSVDLSYN-KLQALAPDLFHGLRKLTTLHMRANAIQFVPVR 179
Query: 354 HFPIDR-LQELEISGN 368
F R L+ L+I N
Sbjct: 180 IFQDCRSLKFLDIGYN 195
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/225 (28%), Positives = 107/225 (47%), Gaps = 2/225 (0%)
Query: 47 EATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
+ T + L HN I ++ AF ++ L +S N+I L + F +R ++LS N L
Sbjct: 90 QLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKL 149
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
+ L D F G I + V+ F+D +L+ LD N+L + +F L
Sbjct: 150 QALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLF 209
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNII 225
L L L +N ++ + A+ +I L L L N + V L ++ L+ +DL+ N I
Sbjct: 210 KLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVV-SSLDWVWNLEKMDLSGNEI 268
Query: 226 ESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
E ++ F ++P L+ L L N +T I L+ +L+ + L+G
Sbjct: 269 EYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAG 313
Score = 78.6 bits (185), Expect = 5e-14
Identities = 58/211 (27%), Positives = 97/211 (45%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL A + + L L + YN + +L + F ++ L L +N + + DAF
Sbjct: 56 NLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRV 115
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
+I+ + TFR + L +D S N+L P+ F L L L +R N+I
Sbjct: 116 KELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQF 175
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P L++LD+ N ++ ++R+ L +L L L +N + V+ F L SL
Sbjct: 176 VPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISL 235
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L L N + ++ S+L + NL + LSG
Sbjct: 236 HSLCLRRNKVAIV-VSSLDWVWNLEKMDLSG 265
Score = 50.0 bits (114), Expect = 2e-05
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 9/210 (4%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + ++ L +L L L++N I SV F L ++ L LS N +T +P
Sbjct: 70 LSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQITQLP 129
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
+ + NL + LS + + R F D +L+
Sbjct: 130 NTTFRPMPNLRSVDLS-YNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCRSLK 188
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFAC 372
+ + N +++ + F G KLT +++++N L + +HFP + L L + N A
Sbjct: 189 FLDIGYN-QLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAI 247
Query: 373 NCSLL-WLWKLGKDSETTTKKSGNSSEFLK 401
S L W+W L K SGN E+++
Sbjct: 248 VVSSLDWVWNLEK-----MDLSGNEIEYME 272
Score = 45.2 bits (102), Expect = 6e-04
Identities = 39/153 (25%), Positives = 68/153 (44%), Gaps = 2/153 (1%)
Query: 49 TLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR 107
T +++ NAI + + F L LDI YN++ L +F ++ L+L +N L +
Sbjct: 164 TTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVK 223
Query: 108 LDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSL 167
++ F +++ I V + + LE++D S N + EP FE + L
Sbjct: 224 VNFAHFPRLISLHSLCLRRNKVA-IVVSSLDWVWNLEKMDLSGNEIEYMEPHVFETVPHL 282
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+ L L +N + I L L + L+ NL
Sbjct: 283 QSLQLDSNRLTYIEPRILNSWKSLTSITLAGNL 315
Score = 36.3 bits (80), Expect = 0.29
Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 3/136 (2%)
Query: 234 HSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
H+L L L L N+++ + + L L+ LYL
Sbjct: 62 HNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLS 121
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
+ + + F NL+ + ++ N K++ + P LFHG KLT ++M+ NA++ +
Sbjct: 122 SNQITQ-LPNTTFRPMPNLRSVDLSYN-KLQALAPDLFHGLRKLTTLHMRANAIQFVPVR 179
Query: 354 HFPIDR-LQELEISGN 368
F R L+ L+I N
Sbjct: 180 IFQDCRSLKFLDIGYN 195
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/201 (29%), Positives = 92/201 (45%), Gaps = 1/201 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHL 266
NN+ PT A+ LSNL L
Sbjct: 243 YNNLDEFPT-AIRTLSNLKEL 262
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/207 (28%), Positives = 91/207 (43%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSSL +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L ++N I S+ + F PSL +
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIH 287
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 288 FYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/240 (26%), Positives = 101/240 (42%), Gaps = 4/240 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ IP A LS+L L+L E A
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRT 255
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
NL+++ + N +R +P + F GNP L I+ +N ++ + S F + L+ L ++G
Sbjct: 256 LSNLKELGFHSN-NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 60.1 bits (139), Expect = 2e-08
Identities = 55/223 (24%), Positives = 97/223 (43%), Gaps = 12/223 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N +D A + L L N I + + F N + ++ +N ++ + +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + F DL+ LE L + ++ + L +L
Sbjct: 299 SAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNL 354
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 355 QVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAI 412
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 413 IHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 452
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/243 (25%), Positives = 106/243 (43%), Gaps = 27/243 (11%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFE------------------- 90
M L N I ++ YAF + L VL + N+I LG + F+
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 91 ----SNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ S ++ L +N ++ + + AFVG I + F+ L L L
Sbjct: 251 TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTL 310
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ +T P+ ++L+ L+L I +P + +L+ LDLS NL++ +
Sbjct: 311 TLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+ ++L+ +DL +N I + F L SLR L+L+ N + +I +A S L +L L
Sbjct: 370 FSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Query: 267 YLS 269
LS
Sbjct: 428 DLS 430
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/191 (27%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L+ L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F L +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/201 (29%), Positives = 92/201 (45%), Gaps = 1/201 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHL 266
NN+ PT A+ LSNL L
Sbjct: 243 YNNLDEFPT-AIRTLSNLKEL 262
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/207 (28%), Positives = 91/207 (43%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSSL +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L ++N I S+ + F PSL +
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIH 287
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 288 FYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/240 (26%), Positives = 101/240 (42%), Gaps = 4/240 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ IP A LS+L L+L E A
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRT 255
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
NL+++ + N +R +P + F GNP L I+ +N ++ + S F + L+ L ++G
Sbjct: 256 LSNLKELGFHSN-NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 60.1 bits (139), Expect = 2e-08
Identities = 55/223 (24%), Positives = 97/223 (43%), Gaps = 12/223 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N +D A + L L N I + + F N + ++ +N ++ + +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + F DL+ LE L + ++ + L +L
Sbjct: 299 SAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNL 354
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 355 QVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAI 412
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 413 IHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 452
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/243 (25%), Positives = 106/243 (43%), Gaps = 27/243 (11%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFE------------------- 90
M L N I ++ YAF + L VL + N+I LG + F+
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 91 ----SNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ S ++ L +N ++ + + AFVG I + F+ L L L
Sbjct: 251 TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTL 310
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ +T P+ ++L+ L+L I +P + +L+ LDLS NL++ +
Sbjct: 311 TLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+ ++L+ +DL +N I + F L SLR L+L+ N + +I +A S L +L L
Sbjct: 370 FSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Query: 267 YLS 269
LS
Sbjct: 428 DLS 430
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/191 (27%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L+ L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F L +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 83.4 bits (197), Expect = 2e-15
Identities = 60/201 (29%), Positives = 92/201 (45%), Gaps = 1/201 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHL 266
NN+ PT A+ LSNL L
Sbjct: 243 YNNLDEFPT-AIRTLSNLKEL 262
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/207 (28%), Positives = 91/207 (43%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSSL +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L ++N I S+ + F PSL +
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIH 287
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 288 FYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/240 (26%), Positives = 101/240 (42%), Gaps = 4/240 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ IP A LS+L L+L E A
Sbjct: 198 IHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRT 255
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
NL+++ + N +R +P + F GNP L I+ +N ++ + S F + L+ L ++G
Sbjct: 256 LSNLKELGFHSN-NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 60.1 bits (139), Expect = 2e-08
Identities = 55/223 (24%), Positives = 97/223 (43%), Gaps = 12/223 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N +D A + L L N I + + F N + ++ +N ++ + +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + F DL+ LE L + ++ + L +L
Sbjct: 299 SAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNL 354
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 355 QVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAI 412
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 413 IHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 452
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/243 (25%), Positives = 106/243 (43%), Gaps = 27/243 (11%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFE------------------- 90
M L N I ++ YAF + L VL + N+I LG + F+
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 91 ----SNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ S ++ L +N ++ + + AFVG I + F+ L L L
Sbjct: 251 TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTL 310
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ +T P+ ++L+ L+L I +P + +L+ LDLS NL++ +
Sbjct: 311 TLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+ ++L+ +DL +N I + F L SLR L+L+ N + +I +A S L +L L
Sbjct: 370 FSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Query: 267 YLS 269
LS
Sbjct: 428 DLS 430
Score = 54.8 bits (126), Expect = 8e-07
Identities = 52/191 (27%), Positives = 82/191 (42%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L+ L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F L +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 83.0 bits (196), Expect = 3e-15
Identities = 68/246 (27%), Positives = 108/246 (43%), Gaps = 2/246 (0%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
CD C N +L+ VP+ N TL++L N I +L F YT+L + + +N I
Sbjct: 115 CDCKETELECVNGDLKSVPMISN-NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCI 173
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
+ + F ++ L L++N + L F I+ I + F L+
Sbjct: 174 RHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLN 233
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLI 201
+L L NN L + + L + L N I + ++ L LDLS N I
Sbjct: 234 SLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTI 293
Query: 202 QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLS 261
++S H LK L+ L+L++N + + + F SL L+ LDL + I T +
Sbjct: 294 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMK 353
Query: 262 NLSHLY 267
NLSH+Y
Sbjct: 354 NLSHIY 359
Score = 69.3 bits (162), Expect = 3e-11
Identities = 50/198 (25%), Positives = 87/198 (43%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
+T+L + NKI L + F ++++ + L +N ++ + + AF G I+
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCIT 198
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
+ F+DL L L +N + F L+SL LS+ NN + +P +
Sbjct: 199 TLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQ 258
Query: 191 LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L ++DL N I+ ++ L LDL++N I + F L L+ L+LS N +
Sbjct: 259 LNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKLNLSSNPLM 318
Query: 251 LIPTSALSKLSNLSHLYL 268
+ + L L L L
Sbjct: 319 YLHKNQFESLKQLQSLDL 336
Score = 54.8 bits (126), Expect = 8e-07
Identities = 43/174 (24%), Positives = 70/174 (40%), Gaps = 1/174 (0%)
Query: 50 LMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L HN I L F QLT L + N I + F + + L++ NN+L+ L
Sbjct: 189 ILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEAL 248
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
K I + TF +L LD S+N + P F+ L L+
Sbjct: 249 PKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQ 308
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
L+L +N ++ + + L+ LDL I ++ +K L H+ N
Sbjct: 309 KLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKN 362
Score = 54.4 bits (125), Expect = 1e-06
Identities = 41/132 (31%), Positives = 61/132 (46%), Gaps = 4/132 (3%)
Query: 31 SCANANLEIVPIQL---NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGS 86
S N LE +P Q+ P+ ++L N I L + F LTVLD+S N I +L
Sbjct: 239 SMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSP 298
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
F+ ++ LNLS+N L L K+ F EI NI+ + F+ + L +
Sbjct: 299 HLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHI 358
Query: 147 DFSNNRLVTFEP 158
F N R ++ P
Sbjct: 359 YFKNFRYCSYAP 370
Score = 52.8 bits (121), Expect = 3e-06
Identities = 50/187 (26%), Positives = 77/187 (41%), Gaps = 1/187 (0%)
Query: 83 DLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA 142
DL S SN+ + L+L N + L F+ I +I + F L
Sbjct: 128 DLKSVPMISNN-VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCN 186
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L+ L ++N + T P F+ L L L L +N I I + L +L + N ++
Sbjct: 187 LQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLE 246
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ + + +L +DL N I+ + F S SL LDLS N +T + L
Sbjct: 247 ALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKL 306
Query: 263 LSHLYLS 269
L L LS
Sbjct: 307 LQKLNLS 313
>L01131-1|AAA52301.1| 347|Homo sapiens decorin protein.
Length = 347
Score = 82.6 bits (195), Expect = 3e-15
Identities = 68/240 (28%), Positives = 102/240 (42%), Gaps = 11/240 (4%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP RC C LR C++ L+ VP L P+ TL++L +N I + F L L
Sbjct: 53 VCPFRCQCH--LRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + F ++ L LS N LK L + EI+ +
Sbjct: 111 ILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM---PKTLQELRAHENEITKVRK 167
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF L+ + ++ N L + E F+ + L + + + +I IP G L
Sbjct: 168 VTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ---GLPPSLT 224
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I +V L L L L L+ N I +VD + P LR L L +N +T +
Sbjct: 225 ELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRV 284
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L NN + + F +IS + F L LERL S N+L
Sbjct: 86 LDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL- 144
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ--VSRHGLPFLKEL 215
PE +L+ L N I + + + ++L N ++ + +K+L
Sbjct: 145 PEKMP--KTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKL 202
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++ + + I S+ Q G PSL L L N ++ + ++L L+NL+ L LS
Sbjct: 203 SYIRIADTNITSIPQ-GLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLS 253
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 82.6 bits (195), Expect = 3e-15
Identities = 69/258 (26%), Positives = 106/258 (41%), Gaps = 6/258 (2%)
Query: 15 TLCPVRCMC--DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQL 71
T CP C C D + +A C+ L VP L+P ++L+ N + L F+ L
Sbjct: 33 TACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFL 92
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L +S N + + + F ++ L L NN L + +A IS
Sbjct: 93 EELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISL 152
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ ++F LS+L L +N L L +L+ ++L N I IP + L
Sbjct: 153 VPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSL 212
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L L N IQ + H L L+ LDLN N ++ + +L L+ L +NN+
Sbjct: 213 VVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKA 271
Query: 252 IPTSAL--SKLSNLSHLY 267
IP A + L H Y
Sbjct: 272 IPEKAFMGNPLLQTIHFY 289
Score = 81.4 bits (192), Expect = 8e-15
Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 4/232 (1%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 86 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 145
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 146 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 205
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L++L L+L E A LQ++
Sbjct: 206 FQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE--FPVAIRTLGRLQELG 263
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
++N ++ +P + F GNP L I+ +N ++ + S F + +L L ++G
Sbjct: 264 FHNN-NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 314
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 8 WSAAAAKTLCPVRCMCD-DALRAASCANANLEIVP---IQLNPEATLMNLTHNAIDNL-L 62
W A T PVR + + AL+A + A + +P Q +++L +N I +L
Sbjct: 168 WLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGT 227
Query: 63 YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXX 122
++F L LD++YNK+ + + ++ L NN +K + + AF+G
Sbjct: 228 HSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 286
Query: 123 XXXXXEIS-----------NIH---------VQTFRDL---SALERLDFSNNRLVTFEPE 159
I +H +Q F DL ++LE L + +
Sbjct: 287 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 346
Query: 160 TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD 219
+ L L++L L +N I ++PS L LE + L N I ++ L L+ LD
Sbjct: 347 MCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 404
Query: 220 LNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L+ N I S+ F +L SL LDL+DN +T +P L+ L L HL L G
Sbjct: 405 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKG 452
Score = 67.3 bits (157), Expect = 1e-10
Identities = 44/124 (35%), Positives = 59/124 (47%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N L +P F L L+ L L N + IP + L+ L L N + +
Sbjct: 71 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L
Sbjct: 131 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 58.8 bits (136), Expect = 5e-08
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 4/255 (1%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
+L+LS N L L F +S+I Q F L +L+ L NN+L
Sbjct: 70 YLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGI 129
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
E L SL+ L L N I +P + + L +L L +N + ++ L L L+
Sbjct: 130 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 189
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXX 276
+ L N I + F +L SL L L +N + + T + L NL L L+
Sbjct: 190 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN--YNKLQ 247
Query: 277 XXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPK 336
+ I +AF+ N LQ I DN ++ V F PK
Sbjct: 248 EFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDN-PIQFVGRSAFQYLPK 306
Query: 337 LTNIYMKNNALETLE 351
L + + N A++ E
Sbjct: 307 LHTLSL-NGAMDIQE 320
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T L +L ++ I L S + +R L LS+N ++ L +
Sbjct: 328 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 385
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TF LS+L+ LD S N + + PE F L SL L L +N + +P A LG +
Sbjct: 386 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGL 445
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELK 216
+HL+ L + L Q S+ P L+ L+
Sbjct: 446 MHLK-LKGNLALSQAFSKDSFPKLRILE 472
>BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and Ig
domain containing 1 protein.
Length = 620
Score = 82.2 bits (194), Expect = 4e-15
Identities = 76/315 (24%), Positives = 129/315 (40%), Gaps = 5/315 (1%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T+ +LD+ N+I L + F S + L L+ N + ++ AF
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ I + F LS L +LD S N++V F+ L +LK L + +N ++ I +
Sbjct: 131 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 190
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-N 247
LE L L + + + L L L L L + I ++ F L L+ L++S
Sbjct: 191 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWP 250
Query: 248 NMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + + L L NL+ L ++ I+
Sbjct: 251 YLDTMTPNCLYGL-NLTSLSIT-HCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLH 308
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
+ + LQ+I + ++ V P F G L + + N L TLE S F + L+ L +
Sbjct: 309 ELLRLQEIQLVGG-QLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 367
Query: 367 GNPFACNCSLLWLWK 381
NP AC+C LLW+++
Sbjct: 368 SNPLACDCRLLWVFR 382
Score = 76.2 bits (179), Expect = 3e-13
Identities = 68/261 (26%), Positives = 113/261 (43%), Gaps = 3/261 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
+ + T CP RC C RA C VP + E L++L N I L F +
Sbjct: 36 SGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFP 95
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
L L+++ N + + F + +R L L +N LK + F G +I
Sbjct: 96 HLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKI 155
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+ F+DL L+ L+ +N LV F L+SL+ L+L ++ IP+ L +
Sbjct: 156 VILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLH 215
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L I + + L LK L++++ ++++ + L +L L ++ N
Sbjct: 216 GLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCN 274
Query: 249 MTLIPTSALSKLSNLSHLYLS 269
+T +P A+ L L L LS
Sbjct: 275 LTAVPYLAVRHLVYLRFLNLS 295
Score = 58.8 bits (136), Expect = 5e-08
Identities = 50/209 (23%), Positives = 90/209 (43%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 136 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
+++I + L L L + + +F+ L LK+L + + LD
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
+ N + ++L L ++ + V + L L+ L+L+ N I +++ H L L+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L + ++ A L+ L L +SG
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSG 344
Score = 36.7 bits (81), Expect = 0.22
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L++ + + L + +R LNLS N + ++
Sbjct: 258 NCLYGLNL-TSLSITHCNLTAVPYLAVRHLVY---LRFLNLSYNPISTIEGSMLHELLRL 313
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+++ + FR L+ L L+ S N+L T E F + +L+ L L +N +
Sbjct: 314 QEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
>AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat
neuronal 6A protein.
Length = 620
Score = 82.2 bits (194), Expect = 4e-15
Identities = 76/315 (24%), Positives = 129/315 (40%), Gaps = 5/315 (1%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T+ +LD+ N+I L + F S + L L+ N + ++ AF
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ I + F LS L +LD S N++V F+ L +LK L + +N ++ I +
Sbjct: 131 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 190
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-N 247
LE L L + + + L L L L L + I ++ F L L+ L++S
Sbjct: 191 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWP 250
Query: 248 NMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + + L L NL+ L ++ I+
Sbjct: 251 YLDTMTPNCLYGL-NLTSLSIT-HCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLH 308
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
+ + LQ+I + ++ V P F G L + + N L TLE S F + L+ L +
Sbjct: 309 ELLRLQEIQLVGG-QLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 367
Query: 367 GNPFACNCSLLWLWK 381
NP AC+C LLW+++
Sbjct: 368 SNPLACDCRLLWVFR 382
Score = 76.2 bits (179), Expect = 3e-13
Identities = 68/261 (26%), Positives = 113/261 (43%), Gaps = 3/261 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
+ + T CP RC C RA C VP + E L++L N I L F +
Sbjct: 36 SGSATGCPPRCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFP 95
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
L L+++ N + + F + +R L L +N LK + F G +I
Sbjct: 96 HLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKI 155
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+ F+DL L+ L+ +N LV F L+SL+ L+L ++ IP+ L +
Sbjct: 156 VILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLH 215
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L I + + L LK L++++ ++++ + L +L L ++ N
Sbjct: 216 GLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCN 274
Query: 249 MTLIPTSALSKLSNLSHLYLS 269
+T +P A+ L L L LS
Sbjct: 275 LTAVPYLAVRHLVYLRFLNLS 295
Score = 58.8 bits (136), Expect = 5e-08
Identities = 50/209 (23%), Positives = 90/209 (43%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 136 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
+++I + L L L + + +F+ L LK+L + + LD
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
+ N + ++L L ++ + V + L L+ L+L+ N I +++ H L L+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L + ++ A L+ L L +SG
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSG 344
Score = 36.7 bits (81), Expect = 0.22
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L++ + + L + +R LNLS N + ++
Sbjct: 258 NCLYGLNL-TSLSITHCNLTAVPYLAVRHLVY---LRFLNLSYNPISTIEGSMLHELLRL 313
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+++ + FR L+ L L+ S N+L T E F + +L+ L L +N +
Sbjct: 314 QEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
>AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein
protein.
Length = 577
Score = 82.2 bits (194), Expect = 4e-15
Identities = 76/315 (24%), Positives = 129/315 (40%), Gaps = 5/315 (1%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T+ +LD+ N+I L + F S + L L+ N + ++ AF
Sbjct: 28 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 87
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ I + F LS L +LD S N++V F+ L +LK L + +N ++ I +
Sbjct: 88 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 147
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-N 247
LE L L + + + L L L L L + I ++ F L L+ L++S
Sbjct: 148 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWP 207
Query: 248 NMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + + L L NL+ L ++ I+
Sbjct: 208 YLDTMTPNCLYGL-NLTSLSIT-HCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLH 265
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
+ + LQ+I + ++ V P F G L + + N L TLE S F + L+ L +
Sbjct: 266 ELLRLQEIQLVGG-QLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 324
Query: 367 GNPFACNCSLLWLWK 381
NP AC+C LLW+++
Sbjct: 325 SNPLACDCRLLWVFR 339
Score = 69.7 bits (163), Expect = 3e-11
Identities = 65/252 (25%), Positives = 108/252 (42%), Gaps = 3/252 (1%)
Query: 20 RCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISY 78
RC C RA C VP + E L++L N I L F + L L+++
Sbjct: 2 RCECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNE 61
Query: 79 NKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFR 138
N + + F + +R L L +N LK + F G +I + F+
Sbjct: 62 NIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQ 121
Query: 139 DLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
DL L+ L+ +N LV F L+SL+ L+L ++ IP+ L + L L L
Sbjct: 122 DLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRH 181
Query: 199 NLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
I + + L LK L++++ ++++ + L +L L ++ N+T +P A+
Sbjct: 182 LNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCNLTAVPYLAV 240
Query: 258 SKLSNLSHLYLS 269
L L L LS
Sbjct: 241 RHLVYLRFLNLS 252
Score = 58.8 bits (136), Expect = 5e-08
Identities = 50/209 (23%), Positives = 90/209 (43%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 93 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 152
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
+++I + L L L + + +F+ L LK+L + + LD
Sbjct: 153 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 212
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
+ N + ++L L ++ + V + L L+ L+L+ N I +++ H L L+
Sbjct: 213 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 272
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L + ++ A L+ L L +SG
Sbjct: 273 IQLVGGQLAVVEPYAFRGLNYLRVLNVSG 301
Score = 36.7 bits (81), Expect = 0.22
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L++ + + L + +R LNLS N + ++
Sbjct: 215 NCLYGLNL-TSLSITHCNLTAVPYLAVRHLVY---LRFLNLSYNPISTIEGSMLHELLRL 270
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+++ + FR L+ L L+ S N+L T E F + +L+ L L +N +
Sbjct: 271 QEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 328
>BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 5 protein.
Length = 719
Score = 81.8 bits (193), Expect = 6e-15
Identities = 57/197 (28%), Positives = 87/197 (44%), Gaps = 3/197 (1%)
Query: 11 AAAKTLCPVRCMCD--DALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNL 67
A +CP RC+C A CA L VP ++ + L N + N+ F
Sbjct: 14 AVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFAN 73
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
T L L +S N I + F +R L+L++N L ++ D F G
Sbjct: 74 MTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNN 133
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+++ I F D+ ALE LD S N L T + E + SL LSL +N I +IP
Sbjct: 134 QLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSH 193
Query: 188 VIHLEYLDLSENLIQQV 204
+ + LD++ N +Q++
Sbjct: 194 LHKMTRLDVTSNKLQKL 210
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/160 (28%), Positives = 73/160 (45%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF+ + + F IS I F DL L L ++NRL
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
+ F LS+L L L NN + I S V LE LDLS N ++ + + + L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
L L++N+I+++ + F L + LD++ N + +P L
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL 215
Score = 66.9 bits (156), Expect = 2e-10
Identities = 65/250 (26%), Positives = 94/250 (37%), Gaps = 34/250 (13%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N + + R + L L L+ N I + F L +LR L L+ N +T I
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
S LSNL HL L+ E I A ++L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL-ETIPWDAVEKMVSLH 174
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISG------ 367
+ ++ N+ + +P F K+T + + +N L+ L R Q L SG
Sbjct: 175 TLSLDHNM-IDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL-FQRAQVLATSGIISPST 232
Query: 368 -------NPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLF 420
NP CNC LLWL +L ++ + T C+ P L G F
Sbjct: 233 FALSFGGNPLHCNCELLWLRRLSREDDLET------------------CASPPLLTGRYF 274
Query: 421 VQIPESEFGC 430
IPE EF C
Sbjct: 275 WSIPEEEFLC 284
Score = 57.6 bits (133), Expect = 1e-07
Identities = 37/123 (30%), Positives = 61/123 (49%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L ++N + + + F ++SL L+L N+I I + +L L L+ N + +++
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L HL LNNN + + F + +L LDLS NN+ IP A+ K+ +L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 266 LYL 268
L L
Sbjct: 176 LSL 178
>AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ30803 fis, clone FEBRA2001245, weakly similar to
NAG14. ).
Length = 719
Score = 81.8 bits (193), Expect = 6e-15
Identities = 57/197 (28%), Positives = 87/197 (44%), Gaps = 3/197 (1%)
Query: 11 AAAKTLCPVRCMCD--DALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNL 67
A +CP RC+C A CA L VP ++ + L N + N+ F
Sbjct: 14 AVKAQICPKRCVCQILSPNLATLCAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFAN 73
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
T L L +S N I + F +R L+L++N L ++ D F G
Sbjct: 74 MTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNN 133
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+++ I F D+ ALE LD S N L T + E + SL LSL +N I +IP
Sbjct: 134 QLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSH 193
Query: 188 VIHLEYLDLSENLIQQV 204
+ + LD++ N +Q++
Sbjct: 194 LHKMTRLDVTSNKLQKL 210
Score = 71.7 bits (168), Expect = 6e-12
Identities = 46/160 (28%), Positives = 73/160 (45%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF+ + + F IS I F DL L L ++NRL
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
+ F LS+L L L NN + I S V LE LDLS N ++ + + + L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL 257
L L++N+I+++ + F L + LD++ N + +P L
Sbjct: 176 LSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL 215
Score = 66.9 bits (156), Expect = 2e-10
Identities = 65/250 (26%), Positives = 94/250 (37%), Gaps = 34/250 (13%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N + + R + L L L+ N I + F L +LR L L+ N +T I
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
S LSNL HL L+ E I A ++L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNL-ETIPWDAVEKMVSLH 174
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISG------ 367
+ ++ N+ + +P F K+T + + +N L+ L R Q L SG
Sbjct: 175 TLSLDHNM-IDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL-FQRAQVLATSGIISPST 232
Query: 368 -------NPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLF 420
NP CNC LLWL +L ++ + T C+ P L G F
Sbjct: 233 FALSFGGNPLHCNCELLWLRRLSREDDLET------------------CASPPLLTGRYF 274
Query: 421 VQIPESEFGC 430
IPE EF C
Sbjct: 275 WSIPEEEFLC 284
Score = 57.6 bits (133), Expect = 1e-07
Identities = 37/123 (30%), Positives = 61/123 (49%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L ++N + + + F ++SL L+L N+I I + +L L L+ N + +++
Sbjct: 56 LRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKIT 115
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L HL LNNN + + F + +L LDLS NN+ IP A+ K+ +L
Sbjct: 116 NDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHT 175
Query: 266 LYL 268
L L
Sbjct: 176 LSL 178
>BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein.
Length = 614
Score = 81.4 bits (192), Expect = 8e-15
Identities = 75/315 (23%), Positives = 129/315 (40%), Gaps = 5/315 (1%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T+ +LD+ N+I L + F S + L L+ N + ++ AF
Sbjct: 65 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 124
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ I + F LS L +LD S N++V F+ L +L+ L + +N ++ I +
Sbjct: 125 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGL 184
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-N 247
LE L L + + + L L L L L + I ++ F L L+ L++S
Sbjct: 185 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWP 244
Query: 248 NMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + + L L NL+ L ++ I+
Sbjct: 245 YLDTMTPNCLYGL-NLTSLSIT-HCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLH 302
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
+ + LQ+I + ++ V P F G L + + N L TLE S F + L+ L +
Sbjct: 303 ELLRLQEIQLVGG-QLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 361
Query: 367 GNPFACNCSLLWLWK 381
NP AC+C LLW+++
Sbjct: 362 SNPLACDCRLLWVFR 376
Score = 71.3 bits (167), Expect = 8e-12
Identities = 67/261 (25%), Positives = 111/261 (42%), Gaps = 3/261 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
+ + T CP R C RA C VP + E L++L N I L F +
Sbjct: 30 SGSATGCPPRYECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFP 89
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
L L+++ N + + F + +R L L +N LK + F G +I
Sbjct: 90 HLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKI 149
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+ F+DL L L+ +N LV F L+SL+ L+L ++ IP+ L +
Sbjct: 150 VILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLH 209
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L I + + L LK L++++ ++++ + L +L L ++ N
Sbjct: 210 GLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCN 268
Query: 249 MTLIPTSALSKLSNLSHLYLS 269
+T +P A+ L L L LS
Sbjct: 269 LTAVPYLAVRHLVYLRFLNLS 289
Score = 60.1 bits (139), Expect = 2e-08
Identities = 51/209 (24%), Positives = 90/209 (43%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT LDIS NKI+ L F+ +R L + +N L + AF G
Sbjct: 130 LGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLRSLEVGDNDLVYISHRAFSGLNSLEQ 189
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
+++I + L L L + + +F+ L LK+L + + LD
Sbjct: 190 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 249
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
+ N + ++L L ++ + V + L L+ L+L+ N I +++ H L L+
Sbjct: 250 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNRISTIEGSMLHELLRLQE 309
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L + ++ A L+ L L +SG
Sbjct: 310 IQLVGGQLAVVEPYAFRGLNYLRVLNVSG 338
Score = 37.1 bits (82), Expect = 0.17
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L++ + + L + +R LNLS N + ++
Sbjct: 252 NCLYGLNL-TSLSITHCNLTAVPYLAVRHLVY---LRFLNLSYNRISTIEGSMLHELLRL 307
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+++ + FR L+ L L+ S N+L T E F + +L+ L L +N +
Sbjct: 308 QEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 365
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 81.4 bits (192), Expect = 8e-15
Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 4/232 (1%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 34 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 93
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 94 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 153
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L++L L+L E A LQ++
Sbjct: 154 FQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE--FPVAIRTLGRLQELG 211
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
++N ++ +P + F GNP L I+ +N ++ + S F + +L L ++G
Sbjct: 212 FHNN-NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/197 (28%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
++ D+S N + +L F + L LS N L + AF G ++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVI 189
I + +L +L+ L N L++ PE +FE LSSL+ L L +N++ +IP L +
Sbjct: 76 GIPAEALWELPSLQSLRLDAN-LISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP 134
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ + L+ N I + + L L L L+NN I+ + F L +L LDL+ N +
Sbjct: 135 ALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKL 194
Query: 250 TLIPTSALSKLSNLSHL 266
P A+ L L L
Sbjct: 195 QEFPV-AIRTLGRLQEL 210
Score = 71.7 bits (168), Expect = 6e-12
Identities = 52/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L +L + N++ + +E ++ L L N + + + +F G
Sbjct: 57 AFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLW 116
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I V+ +L AL+ + + NR+ F+ L+SL +L L NN I + +
Sbjct: 117 LDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTH 176
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ + +LE LDL+ N +Q+ + L L+ L +NN I+++ + F P L+ +
Sbjct: 177 SFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 235
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 236 FYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 8 WSAAAAKTLCPVRCMCD-DALRAASCANANLEIVP---IQLNPEATLMNLTHNAIDNL-L 62
W A T PVR + + AL+A + A + +P Q +++L +N I +L
Sbjct: 116 WLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGT 175
Query: 63 YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXX 122
++F L LD++YNK+ + + ++ L NN +K + + AF+G
Sbjct: 176 HSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 234
Query: 123 XXXXXEIS-----------NIH---------VQTFRDL---SALERLDFSNNRLVTFEPE 159
I +H +Q F DL ++LE L + +
Sbjct: 235 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 294
Query: 160 TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD 219
+ L L++L L +N I ++PS L LE + L N I ++ L L+ LD
Sbjct: 295 MCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 352
Query: 220 LNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L+ N I S+ F +L SL LDL+DN +T +P L+ L L HL L G
Sbjct: 353 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKG 400
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/123 (34%), Positives = 58/123 (47%)
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D S N L +P F L L+ L L N + IP + L+ L L N + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 267 YLS 269
L+
Sbjct: 140 TLA 142
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/253 (25%), Positives = 98/253 (38%), Gaps = 4/253 (1%)
Query: 99 NLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
+LS N L L F +S+I Q F L +L+ L NN+L
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 159 ETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHL 218
E L SL+ L L N I +P + + L +L L +N + ++ L L L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 219 DLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
L N I + F +L SL L L +N + + T + L NL L L+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN--YNKLQEF 197
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+ I +AF+ N LQ I DN ++ V F PKL
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDN-PIQFVGRSAFQYLPKLH 256
Query: 339 NIYMKNNALETLE 351
+ + N A++ E
Sbjct: 257 TLSL-NGAMDIQE 268
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T L +L ++ I L S + +R L LS+N ++ L +
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TF LS+L+ LD S N + + PE F L SL L L +N + +P A LG +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGL 393
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELK 216
+HL+ L + L Q S+ P L+ L+
Sbjct: 394 MHLK-LKGNLALSQAFSKDSFPKLRILE 420
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 81.4 bits (192), Expect = 8e-15
Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 4/232 (1%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 34 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 93
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 94 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 153
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L++L L+L E A LQ++
Sbjct: 154 FQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE--FPVAIRTLGRLQELG 211
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
++N ++ +P + F GNP L I+ +N ++ + S F + +L L ++G
Sbjct: 212 FHNN-NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/197 (28%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
++ D+S N + +L F + L LS N L + AF G ++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVI 189
I + +L +L+ L N L++ PE +FE LSSL+ L L +N++ +IP L +
Sbjct: 76 GIPAEALWELPSLQSLRLDAN-LISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP 134
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ + L+ N I + + L L L L+NN I+ + F L +L LDL+ N +
Sbjct: 135 ALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKL 194
Query: 250 TLIPTSALSKLSNLSHL 266
P A+ L L L
Sbjct: 195 QEFPV-AIRTLGRLQEL 210
Score = 71.7 bits (168), Expect = 6e-12
Identities = 52/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L +L + N++ + +E ++ L L N + + + +F G
Sbjct: 57 AFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLW 116
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I V+ +L AL+ + + NR+ F+ L+SL +L L NN I + +
Sbjct: 117 LDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTH 176
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ + +LE LDL+ N +Q+ + L L+ L +NN I+++ + F P L+ +
Sbjct: 177 SFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 235
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 236 FYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 8 WSAAAAKTLCPVRCMCD-DALRAASCANANLEIVP---IQLNPEATLMNLTHNAIDNL-L 62
W A T PVR + + AL+A + A + +P Q +++L +N I +L
Sbjct: 116 WLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGT 175
Query: 63 YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXX 122
++F L LD++YNK+ + + ++ L NN +K + + AF+G
Sbjct: 176 HSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 234
Query: 123 XXXXXEIS-----------NIH---------VQTFRDL---SALERLDFSNNRLVTFEPE 159
I +H +Q F DL ++LE L + +
Sbjct: 235 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 294
Query: 160 TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD 219
+ L L++L L +N I ++PS L LE + L N I ++ L L+ LD
Sbjct: 295 MCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 352
Query: 220 LNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L+ N I S+ F +L SL LDL+DN +T +P L+ L L HL L G
Sbjct: 353 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKG 400
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/123 (34%), Positives = 58/123 (47%)
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D S N L +P F L L+ L L N + IP + L+ L L N + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 267 YLS 269
L+
Sbjct: 140 TLA 142
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/253 (25%), Positives = 98/253 (38%), Gaps = 4/253 (1%)
Query: 99 NLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
+LS N L L F +S+I Q F L +L+ L NN+L
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 159 ETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHL 218
E L SL+ L L N I +P + + L +L L +N + ++ L L L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 219 DLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
L N I + F +L SL L L +N + + T + L NL L L+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN--YNKLQEF 197
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+ I +AF+ N LQ I DN ++ V F PKL
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDN-PIQFVGRSAFQYLPKLH 256
Query: 339 NIYMKNNALETLE 351
+ + N A++ E
Sbjct: 257 TLSL-NGAMDIQE 268
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T L +L ++ I L S + +R L LS+N ++ L +
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TF LS+L+ LD S N + + PE F L SL L L +N + +P A LG +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGL 393
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELK 216
+HL+ L + L Q S+ P L+ L+
Sbjct: 394 MHLK-LKGNLALSQAFSKDSFPKLRILE 420
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 81.4 bits (192), Expect = 8e-15
Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 4/232 (1%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 34 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 93
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 94 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 153
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L++L L+L E A LQ++
Sbjct: 154 FQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE--FPVAIRTLGRLQELG 211
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
++N ++ +P + F GNP L I+ +N ++ + S F + +L L ++G
Sbjct: 212 FHNN-NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 73.3 bits (172), Expect = 2e-12
Identities = 56/197 (28%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
++ D+S N + +L F + L LS N L + AF G ++
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG 75
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVI 189
I + +L +L+ L N L++ PE +FE LSSL+ L L +N++ +IP L +
Sbjct: 76 GIPAEALWELPSLQSLRLDAN-LISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLP 134
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ + L+ N I + + L L L L+NN I+ + F L +L LDL+ N +
Sbjct: 135 ALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKL 194
Query: 250 TLIPTSALSKLSNLSHL 266
P A+ L L L
Sbjct: 195 QEFPV-AIRTLGRLQEL 210
Score = 71.7 bits (168), Expect = 6e-12
Identities = 52/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L +L + N++ + +E ++ L L N + + + +F G
Sbjct: 57 AFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLW 116
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I V+ +L AL+ + + NR+ F+ L+SL +L L NN I + +
Sbjct: 117 LDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTH 176
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ + +LE LDL+ N +Q+ + L L+ L +NN I+++ + F P L+ +
Sbjct: 177 SFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 235
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 236 FYDNPIQFVGRSAFQYLPKLHTLSLNG 262
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 8 WSAAAAKTLCPVRCMCD-DALRAASCANANLEIVP---IQLNPEATLMNLTHNAIDNL-L 62
W A T PVR + + AL+A + A + +P Q +++L +N I +L
Sbjct: 116 WLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGT 175
Query: 63 YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXX 122
++F L LD++YNK+ + + ++ L NN +K + + AF+G
Sbjct: 176 HSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 234
Query: 123 XXXXXEIS-----------NIH---------VQTFRDL---SALERLDFSNNRLVTFEPE 159
I +H +Q F DL ++LE L + +
Sbjct: 235 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 294
Query: 160 TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD 219
+ L L++L L +N I ++PS L LE + L N I ++ L L+ LD
Sbjct: 295 MCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 352
Query: 220 LNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L+ N I S+ F +L SL LDL+DN +T +P L+ L L HL L G
Sbjct: 353 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKG 400
Score = 65.7 bits (153), Expect = 4e-10
Identities = 43/123 (34%), Positives = 58/123 (47%)
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D S N L +P F L L+ L L N + IP + L+ L L N + +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 267 YLS 269
L+
Sbjct: 140 TLA 142
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/253 (25%), Positives = 98/253 (38%), Gaps = 4/253 (1%)
Query: 99 NLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
+LS N L L F +S+I Q F L +L+ L NN+L
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 159 ETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHL 218
E L SL+ L L N I +P + + L +L L +N + ++ L L L+ +
Sbjct: 80 EALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAM 139
Query: 219 DLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
L N I + F +L SL L L +N + + T + L NL L L+
Sbjct: 140 TLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN--YNKLQEF 197
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+ I +AF+ N LQ I DN ++ V F PKL
Sbjct: 198 PVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDN-PIQFVGRSAFQYLPKLH 256
Query: 339 NIYMKNNALETLE 351
+ + N A++ E
Sbjct: 257 TLSL-NGAMDIQE 268
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T L +L ++ I L S + +R L LS+N ++ L +
Sbjct: 276 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 333
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TF LS+L+ LD S N + + PE F L SL L L +N + +P A LG +
Sbjct: 334 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGL 393
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELK 216
+HL+ L + L Q S+ P L+ L+
Sbjct: 394 MHLK-LKGNLALSQAFSKDSFPKLRILE 420
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 81.4 bits (192), Expect = 8e-15
Identities = 64/232 (27%), Positives = 103/232 (44%), Gaps = 4/232 (1%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 47 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 106
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 107 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 166
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L++L L+L E A LQ++
Sbjct: 167 FQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE--FPVAIRTLGRLQELG 224
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
++N ++ +P + F GNP L I+ +N ++ + S F + +L L ++G
Sbjct: 225 FHNN-NIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNG 275
Score = 76.2 bits (179), Expect = 3e-13
Identities = 65/250 (26%), Positives = 102/250 (40%), Gaps = 4/250 (1%)
Query: 21 CMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYN 79
C D + +A C+ L VP L+P ++L+ N + L F+ L L +S N
Sbjct: 2 CQEDGIMLSADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGN 61
Query: 80 KILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+ + + F ++ L L NN L + +A IS + ++F
Sbjct: 62 HLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEG 121
Query: 140 LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
LS+L L +N L L +L+ ++L N I IP + L L L N
Sbjct: 122 LSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNN 181
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSAL-- 257
IQ + H L L+ LDLN N ++ + +L L+ L +NN+ IP A
Sbjct: 182 RIQHLGTHSFEGLHNLETLDLNYNKLQEF-PVAIRTLGRLQELGFHNNNIKAIPEKAFMG 240
Query: 258 SKLSNLSHLY 267
+ L H Y
Sbjct: 241 NPLLQTIHFY 250
Score = 71.7 bits (168), Expect = 6e-12
Identities = 52/207 (25%), Positives = 96/207 (46%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L +L + N++ + +E ++ L L N + + + +F G
Sbjct: 70 AFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLW 129
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I V+ +L AL+ + + NR+ F+ L+SL +L L NN I + +
Sbjct: 130 LDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTH 189
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ + +LE LDL+ N +Q+ + L L+ L +NN I+++ + F P L+ +
Sbjct: 190 SFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIH 248
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 249 FYDNPIQFVGRSAFQYLPKLHTLSLNG 275
Score = 70.1 bits (164), Expect = 2e-11
Identities = 79/291 (27%), Positives = 126/291 (43%), Gaps = 34/291 (11%)
Query: 8 WSAAAAKTLCPVRCMCD-DALRAASCANANLEIVP---IQLNPEATLMNLTHNAIDNL-L 62
W A T PVR + + AL+A + A + +P Q +++L +N I +L
Sbjct: 129 WLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGT 188
Query: 63 YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXX 122
++F L LD++YNK+ + + ++ L NN +K + + AF+G
Sbjct: 189 HSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTI 247
Query: 123 XXXXXEIS-----------NIH---------VQTFRDL---SALERLDFSNNRLVTFEPE 159
I +H +Q F DL ++LE L + +
Sbjct: 248 HFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSG 307
Query: 160 TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD 219
+ L L++L L +N I ++PS L LE + L N I ++ L L+ LD
Sbjct: 308 MCQQLPRLRVLELSHNQIEELPS--LHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALD 365
Query: 220 LNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
L+ N I S+ F +L SL LDL+DN +T +P L+ L L HL L G
Sbjct: 366 LSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLP---LAGLGGLMHLKLKG 413
Score = 67.3 bits (157), Expect = 1e-10
Identities = 44/124 (35%), Positives = 59/124 (47%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N L +P F L L+ L L N + IP + L+ L L N + +
Sbjct: 32 LDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIP 91
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L
Sbjct: 92 AEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQA 151
Query: 266 LYLS 269
+ L+
Sbjct: 152 MTLA 155
Score = 58.8 bits (136), Expect = 5e-08
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 4/255 (1%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
+L+LS N L L F +S+I Q F L +L+ L NN+L
Sbjct: 31 YLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGI 90
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
E L SL+ L L N I +P + + L +L L +N + ++ L L L+
Sbjct: 91 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQ 150
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXX 276
+ L N I + F +L SL L L +N + + T + L NL L L+
Sbjct: 151 AMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLN--YNKLQ 208
Query: 277 XXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPK 336
+ I +AF+ N LQ I DN ++ V F PK
Sbjct: 209 EFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDN-PIQFVGRSAFQYLPK 267
Query: 337 LTNIYMKNNALETLE 351
L + + N A++ E
Sbjct: 268 LHTLSL-NGAMDIQE 281
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 68/148 (45%), Gaps = 3/148 (2%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T L +L ++ I L S + +R L LS+N ++ L +
Sbjct: 289 TSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP--SLHRCQKLEEIGLQHNR 346
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I TF LS+L+ LD S N + + PE F L SL L L +N + +P A LG +
Sbjct: 347 IWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGL 406
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELK 216
+HL+ L + L Q S+ P L+ L+
Sbjct: 407 MHLK-LKGNLALSQAFSKDSFPKLRILE 433
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 66.9 bits (156), Expect = 2e-10
Identities = 87/380 (22%), Positives = 150/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFNEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 81.0 bits (191), Expect = 1e-14
Identities = 79/255 (30%), Positives = 117/255 (45%), Gaps = 8/255 (3%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKI 81
C + A C++ L VP L T++NLTHN + L A F Y+QLT LD+ +N I
Sbjct: 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
L E + ++ LNL +N L +L F I I F
Sbjct: 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH--LEYLDLSEN 199
L LD S+N L + + T L +L+ L L NN I + S L + L+ L+LS N
Sbjct: 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNII--ESVDQLGFH-SLPSLRHLDLSDNNM-TLIPTS 255
I++ S + L L LNN + ++L + S+R+L LS++ + T T+
Sbjct: 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
Query: 256 ALS-KLSNLSHLYLS 269
L K +NL+ L LS
Sbjct: 268 FLGLKWTNLTMLDLS 282
Score = 67.7 bits (158), Expect = 1e-10
Identities = 87/380 (22%), Positives = 151/380 (39%), Gaps = 19/380 (5%)
Query: 37 LEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMR 96
LE ++ N L + + + + N+ Y NL T IS + + +F+ +
Sbjct: 300 LEYFFLEYNNIQHLFSHSLHGLFNVRY-LNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXX--XXXXXXXEISNIHVQTFRDL--SALERLDFSNNR 152
HLN+ +N + + + F G + + +TF L S L L+ + N+
Sbjct: 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
Query: 153 LVTFEPETFEPLSSLKILSLRNNSI-LDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
+ E + F L L++L L N I ++ + ++ + LS N Q++R+
Sbjct: 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
Query: 212 LKELKHLDLNNNIIESVDQLG--FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ L+ L L +++VD F L +L LDLS+NN+ I L L L L L
Sbjct: 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
Query: 270 GXXXXXXXXXXX-------XXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVK 322
+ I F D L+ I + N
Sbjct: 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN-N 597
Query: 323 VREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR-LQELEISGNPFACNCSLLWLW 380
+ +P +F+ L ++ ++ N + ++E F P R L EL++ NPF C C + W
Sbjct: 598 LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI-AW 656
Query: 381 KLGKDSETTTKKSGNSSEFL 400
+ +ET T SS +L
Sbjct: 657 FVNWINETHTNIPELSSHYL 676
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/236 (25%), Positives = 111/236 (47%), Gaps = 17/236 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQ-LTVLDISYNKILDLGSENFE--SNSEMRHLNLSNNFLKR 107
++L+HN + + + + L L +S NKI L SE + +NS ++ L LS+N +K
Sbjct: 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
Query: 108 LDKDAFVGXXXXXXXXXXXXEIS-NIHVQTFRDLS--ALERLDFSNNRLVTFEPETFEPL 164
F ++ ++ + +L+ ++ L SN++L T TF L
Sbjct: 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
Query: 165 --SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
++L +L L N++ + + + ++ LEY L N IQ + H L L +++L+L
Sbjct: 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
Query: 223 NI---------IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + +D F L L HL++ DN++ I ++ + L NL +L LS
Sbjct: 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Score = 54.4 bits (125), Expect = 1e-06
Identities = 53/234 (22%), Positives = 102/234 (43%), Gaps = 14/234 (5%)
Query: 49 TLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+L N + N + +T LT+LD+SYN + +G+++F ++ + L N ++ L
Sbjct: 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
Query: 109 DKDAFVG---------XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPE 159
+ G + I +F+ L LE L+ +N + +
Sbjct: 314 FSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
Query: 160 TFEPLSSLKILSLRNN--SILDIPSANLGFVIH--LEYLDLSENLIQQVSRHGLPFLKEL 215
F L +LK LSL N+ S+ + + + H L L+L++N I ++ +L L
Sbjct: 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
Query: 216 KHLDLN-NNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ LDL N I + + + L ++ + LS N + ++ + + +L L L
Sbjct: 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/201 (29%), Positives = 91/201 (45%), Gaps = 1/201 (0%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + LD+S N I L S + L L+ N L + K AF G
Sbjct: 63 NLSVFTSYLDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQ 122
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
++ ++ + ++L +L+ L N + P F L SL+ L L +N++ +IP
Sbjct: 123 NNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAF 182
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+ L+ + L+ N I + + L L L+NN I S+ + F L SL LDL+
Sbjct: 183 RSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 242
Query: 246 DNNMTLIPTSALSKLSNLSHL 266
NN+ PT A+ LSNL L
Sbjct: 243 YNNLDEFPT-AIRTLSNLKEL 262
Score = 74.9 bits (176), Expect = 7e-13
Identities = 57/207 (27%), Positives = 90/207 (43%), Gaps = 1/207 (0%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF L VL + N++ + +E ++ ++ L L N + + F G
Sbjct: 109 AFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLW 168
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
++ I VQ FR LSAL+ + + N++ F LSS +L L NN I +
Sbjct: 169 LDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKK 228
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLD 243
+ LE LDL+ N + + + L LK L ++N I S+ + F PSL +
Sbjct: 229 CFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIH 287
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSG 270
DN + + SA L L L L+G
Sbjct: 288 FYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 72.9 bits (171), Expect = 3e-12
Identities = 63/240 (26%), Positives = 100/240 (41%), Gaps = 4/240 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + L LE L + N L F L SLK+L L+NN + +P+ L +
Sbjct: 78 ISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL 137
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L N I V L L+HL L++N + + F SL +L+ + L+ N
Sbjct: 138 RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNK 197
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ IP A LS+ L+L E A
Sbjct: 198 IHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRT 255
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISG 367
NL+++ + N +R +P + F GNP L I+ +N ++ + S F + L+ L ++G
Sbjct: 256 LSNLKELGFHSN-NIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 314
Score = 61.7 bits (143), Expect = 7e-09
Identities = 43/124 (34%), Positives = 57/124 (45%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD S N + P L L+ L L N++ IP + L+ L L N ++ V
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L L+ L+ L L+ N I V F L SLRHL L DN +T IP A LS L
Sbjct: 131 TEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQA 190
Query: 266 LYLS 269
+ L+
Sbjct: 191 MTLA 194
Score = 60.1 bits (139), Expect = 2e-08
Identities = 55/223 (24%), Positives = 97/223 (43%), Gaps = 12/223 (5%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N +D A + L L N I + + F N + ++ +N ++ + +
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + F DL+ LE L + ++ + L +L
Sbjct: 299 SAFQHLPELRTLTLNGAS----QITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNL 354
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
++L L N + D+PS ++ L+ +DL N I ++ L L+ L+L N I
Sbjct: 355 QVLDLSYNLLEDLPSFSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAI 412
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ F +LPSL LDLS N ++ P ++ L L+HL L+G
Sbjct: 413 IHPNAFSTLPSLIKLDLSSNLLSSFP---ITGLHGLTHLKLTG 452
Score = 56.4 bits (130), Expect = 3e-07
Identities = 61/243 (25%), Positives = 105/243 (43%), Gaps = 27/243 (11%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFE------------------- 90
M L N I ++ YAF + VL + N+I LG + F+
Sbjct: 191 MTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFP 250
Query: 91 ----SNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ S ++ L +N ++ + + AFVG I + F+ L L L
Sbjct: 251 TAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTL 310
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ +T P+ ++L+ L+L I +P + +L+ LDLS NL++ +
Sbjct: 311 TLNGASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS 369
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+ ++L+ +DL +N I + F L SLR L+L+ N + +I +A S L +L L
Sbjct: 370 FSV--CQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKL 427
Query: 267 YLS 269
LS
Sbjct: 428 DLS 430
Score = 51.2 bits (117), Expect = 9e-06
Identities = 51/191 (26%), Positives = 80/191 (41%), Gaps = 6/191 (3%)
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
++PS NL + YLDLS N I Q+ + LP L L+ L L N + + + F L S
Sbjct: 59 ELPS-NLS--VFTSYLDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYS 115
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXX 298
L+ L L +N + +PT AL L +L L L
Sbjct: 116 LKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALT 175
Query: 299 ERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-I 357
E I +AF LQ + + N K+ +P F +++ NN + +L F +
Sbjct: 176 E-IPVQAFRSLSALQAMTLALN-KIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGL 233
Query: 358 DRLQELEISGN 368
L+ L+++ N
Sbjct: 234 HSLETLDLNYN 244
>BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein.
Length = 778
Score = 80.6 bits (190), Expect = 1e-14
Identities = 71/272 (26%), Positives = 117/272 (43%), Gaps = 3/272 (1%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATL-MNLTHNAID 59
+VL + AA CP C+CD++ R +C NL VP + PE T ++L N +
Sbjct: 33 LVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAI-PELTQRLDLQGNLLK 91
Query: 60 NL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXX 118
+ AF LT LD+ + ++ + F + LNL++N L+ L ++A G
Sbjct: 92 VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGS 151
Query: 119 XXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
+ + TF L AL L+ ++N LV F+ L ++ L L +N++
Sbjct: 152 LRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 211
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+ L + L L L N +Q + L + L L+L +N + + +LP
Sbjct: 212 VLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPG 271
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LR L L + + A + L L L G
Sbjct: 272 LRELLLDGGALQALGPRAFAHCPRLHTLDLRG 303
Score = 66.5 bits (155), Expect = 2e-10
Identities = 64/255 (25%), Positives = 101/255 (39%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C+C R +SC L+ VP + L++L N ++ AF L L
Sbjct: 412 CPRACVCVPESRHSSCEGCGLQAVPRGFRSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLH 471
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ + I +L + + +L LS+N L L A G +
Sbjct: 472 LQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGA 531
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
R L +L L +N + P +L+ + L N I ++ LG LE L
Sbjct: 532 ALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLH 591
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLDLSDNNMTLIPT 254
L N +++V L L L L L+ N + ++ F + SL+HL L+ + + I
Sbjct: 592 LDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICP 651
Query: 255 SALSKLS-NLSHLYL 268
A S L L L+L
Sbjct: 652 GAFSGLGPGLQSLHL 666
Score = 59.7 bits (138), Expect = 3e-08
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 5/250 (2%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L L L + + E L L L L +N + + +A L L YL L
Sbjct: 461 FPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYL 520
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
N QV L L L L L++N ++ + +LR + LS N +T + A
Sbjct: 521 ERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGA 580
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L L L+L D +LQ ++
Sbjct: 581 LGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLF 640
Query: 317 MNDNVKVREVPPRLFHG-NPKLTNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCS 375
+N + + ++ P F G P L +++++ N L L A + +L+ +++S NPF C+C
Sbjct: 641 LNSS-GLEQICPGAFSGLGPGLQSLHLQKNQLRALPALP-SLSQLELIDLSSNPFHCDCQ 698
Query: 376 LLWL--WKLG 383
LL L W G
Sbjct: 699 LLPLHRWLTG 708
Score = 56.4 bits (130), Expect = 3e-07
Identities = 54/243 (22%), Positives = 97/243 (39%), Gaps = 3/243 (1%)
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I F+ + L LD + + F L L +L+L +N + ++P L + L
Sbjct: 93 IPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSL 152
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L+L N ++++ L L L+L +N + + + F L +R L LS N +++
Sbjct: 153 RRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSV 212
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ AL+ L L L L +
Sbjct: 213 LAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALP-G 271
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGNPFA 371
L+++ + D ++ + PR F P+L + ++ N L+TL P +L+ L + GNP
Sbjct: 272 LRELLL-DGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGP-GQLRRLRLQGNPLW 329
Query: 372 CNC 374
C C
Sbjct: 330 CGC 332
Score = 55.2 bits (127), Expect = 6e-07
Identities = 47/178 (26%), Positives = 69/178 (38%)
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
S+ + L+L N + + AF G I+ + L L L S+N+
Sbjct: 441 SDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQ 500
Query: 153 LVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL 212
L E L L L N L +P A L + L L L +N + +++ L
Sbjct: 501 LAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLHDNAVDRLAPGDLGRT 560
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L+ + L+ N I V L L L N + +PT AL L L L LSG
Sbjct: 561 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSG 618
>BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein.
Length = 692
Score = 80.6 bits (190), Expect = 1e-14
Identities = 71/272 (26%), Positives = 117/272 (43%), Gaps = 3/272 (1%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATL-MNLTHNAID 59
+VL + AA CP C+CD++ R +C NL VP + PE T ++L N +
Sbjct: 23 LVLLLLAPARQAATQRCPQACICDNSRRHVACRYQNLTEVPDAI-PELTQRLDLQGNLLK 81
Query: 60 NL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXX 118
+ AF LT LD+ + ++ + F + LNL++N L+ L ++A G
Sbjct: 82 VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGS 141
Query: 119 XXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
+ + TF L AL L+ ++N LV F+ L ++ L L +N++
Sbjct: 142 LRRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 201
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+ L + L L L N +Q + L + L L+L +N + + +LP
Sbjct: 202 VLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPG 261
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LR L L + + A + L L L G
Sbjct: 262 LRELLLDGGALQALGPRAFAHCPRLHTLDLRG 293
Score = 64.9 bits (151), Expect = 7e-10
Identities = 63/255 (24%), Positives = 101/255 (39%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C+C R +SC L+ VP + L++L N ++ AF L L
Sbjct: 402 CPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLH 461
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ + I +L + + ++ LS+N L L A G +
Sbjct: 462 LQHCGIAELEAGALAGLGRLIYVYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGA 521
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
R L +L L +N + P +L+ + L N I ++ LG LE L
Sbjct: 522 ALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLH 581
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLDLSDNNMTLIPT 254
L N +++V L L L L L+ N + ++ F + SL+HL L+ + + I
Sbjct: 582 LDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICP 641
Query: 255 SALSKLS-NLSHLYL 268
A S L L L+L
Sbjct: 642 GAFSGLGPGLQSLHL 656
Score = 54.8 bits (126), Expect = 8e-07
Identities = 54/243 (22%), Positives = 96/243 (39%), Gaps = 3/243 (1%)
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I F+ + L LD + + F L L +L+L +N + ++P L + L
Sbjct: 83 IPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSL 142
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L+L N ++ + L L L+L +N + + + F L +R L LS N +++
Sbjct: 143 RRLELEGNALEGLRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSV 202
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ AL+ L L L L +
Sbjct: 203 LAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALP-G 261
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGNPFA 371
L+++ + D ++ + PR F P+L + ++ N L+TL P +L+ L + GNP
Sbjct: 262 LRELLL-DGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGP-GQLRRLRLQGNPLW 319
Query: 372 CNC 374
C C
Sbjct: 320 CGC 322
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/178 (25%), Positives = 69/178 (38%)
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
S+ + L+L N + + AF G I+ + L L + S+N+
Sbjct: 431 SDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYVYLSDNQ 490
Query: 153 LVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL 212
L E L L L N L +P A L + L L L +N + +++ L
Sbjct: 491 LAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRT 550
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L+ + L+ N I V L L L N + +PT AL L L L LSG
Sbjct: 551 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSG 608
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 80.6 bits (190), Expect = 1e-14
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 1/216 (0%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF L +L +++N I L F+ ++ L L +N + R+ +
Sbjct: 168 LQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQR 227
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + Q + L +D NR+ TF SL +L
Sbjct: 228 LFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLF 287
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N I +P + +L LDLS N I ++S H LK L+ L+L++N + + +
Sbjct: 288 LPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKN 347
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F SL L+ LDL + I T + NLSH+Y
Sbjct: 348 QFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIY 383
Score = 71.3 bits (167), Expect = 8e-12
Identities = 54/199 (27%), Positives = 87/199 (43%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
+T+L + NKI L + F ++++ + L +N ++ + + AF G I+
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCIT 198
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
+ F+DL L L +N + F L+SL LS+ NN + +P +
Sbjct: 199 TLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQ 258
Query: 191 LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L ++DL N I+ ++ L L L N I V + F SL +L LDLS N +T
Sbjct: 259 LNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTIT 318
Query: 251 LIPTSALSKLSNLSHLYLS 269
+ L L L LS
Sbjct: 319 ELSPHLFKDLKLLQKLNLS 337
Score = 48.0 bits (109), Expect = 9e-05
Identities = 30/129 (23%), Positives = 54/129 (41%)
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRL 153
++ ++L N +K L F+ +I + +TF L L LD S+N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
P F+ L L+ L+L +N ++ + + L+ LDL I ++ +K
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMK 377
Query: 214 ELKHLDLNN 222
L H+ N
Sbjct: 378 NLSHIYFKN 386
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 43/94 (45%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L LD+S N I +L F+ ++ LNLS+N L L K+ F
Sbjct: 301 FSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL 360
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
EI NI+ + F+ + L + F N R ++ P
Sbjct: 361 ERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAP 394
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 31 SCANANLEIVPIQL---NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGS 86
S N LE +P Q+ P+ ++L N I L + F LTVL + N+I +
Sbjct: 239 SMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPE 298
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ F S + L+LS+N + L F + +H F L L+ L
Sbjct: 299 KTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSL 358
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRN 174
D + F+P+ +L + +N
Sbjct: 359 DLERIEIPNINTRMFQPMKNLSHIYFKN 386
Score = 41.9 bits (94), Expect = 0.006
Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 3/206 (1%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
+++ +LSL+ N I +P L+ + L N I+ +SR L L+ L LN+N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
I ++ F L L L L DN +T I + L++L L +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVN-NYLEALPKQMCAQ 255
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ + + F+ +L +++ N ++ VP + F L + + +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRN-QIGFVPEKTFSSLKNLGELDLSS 314
Query: 345 NALETLEASHF-PIDRLQELEISGNP 369
N + L F + LQ+L +S NP
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNP 340
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 80.6 bits (190), Expect = 1e-14
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 1/216 (0%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF L +L +++N I L F+ ++ L L +N + R+ +
Sbjct: 168 LQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQR 227
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + Q + L +D NR+ TF SL +L
Sbjct: 228 LFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLF 287
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N I +P + +L LDLS N I ++S H LK L+ L+L++N + + +
Sbjct: 288 LPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKN 347
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F SL L+ LDL + I T + NLSH+Y
Sbjct: 348 QFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIY 383
Score = 71.3 bits (167), Expect = 8e-12
Identities = 54/199 (27%), Positives = 87/199 (43%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
+T+L + NKI L + F ++++ + L +N ++ + + AF G I+
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCIT 198
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
+ F+DL L L +N + F L+SL LS+ NN + +P +
Sbjct: 199 TLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQ 258
Query: 191 LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L ++DL N I+ ++ L L L N I V + F SL +L LDLS N +T
Sbjct: 259 LNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTIT 318
Query: 251 LIPTSALSKLSNLSHLYLS 269
+ L L L LS
Sbjct: 319 ELSPHLFKDLKLLQKLNLS 337
Score = 48.0 bits (109), Expect = 9e-05
Identities = 30/129 (23%), Positives = 54/129 (41%)
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRL 153
++ ++L N +K L F+ +I + +TF L L LD S+N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
P F+ L L+ L+L +N ++ + + L+ LDL I ++ +K
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMK 377
Query: 214 ELKHLDLNN 222
L H+ N
Sbjct: 378 NLSHIYFKN 386
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 43/94 (45%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L LD+S N I +L F+ ++ LNLS+N L L K+ F
Sbjct: 301 FSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL 360
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
EI NI+ + F+ + L + F N R ++ P
Sbjct: 361 ERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAP 394
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 31 SCANANLEIVPIQL---NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGS 86
S N LE +P Q+ P+ ++L N I L + F LTVL + N+I +
Sbjct: 239 SMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPE 298
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ F S + L+LS+N + L F + +H F L L+ L
Sbjct: 299 KTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSL 358
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRN 174
D + F+P+ +L + +N
Sbjct: 359 DLERIEIPNINTRMFQPMKNLSHIYFKN 386
Score = 41.9 bits (94), Expect = 0.006
Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 3/206 (1%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
+++ +LSL+ N I +P L+ + L N I+ +SR L L+ L LN+N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
I ++ F L L L L DN +T I + L++L L +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVN-NYLEALPKQMCAQ 255
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ + + F+ +L +++ N ++ VP + F L + + +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRN-QIGFVPEKTFSSLKNLGELDLSS 314
Query: 345 NALETLEASHF-PIDRLQELEISGNP 369
N + L F + LQ+L +S NP
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNP 340
>AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA
sequence from clone RP4-756G23 on chromosome
22q13.31-13.33. ).
Length = 762
Score = 80.6 bits (190), Expect = 1e-14
Identities = 71/272 (26%), Positives = 117/272 (43%), Gaps = 3/272 (1%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATL-MNLTHNAID 59
+VL + AA CP C+CD++ R +C NL VP + PE T ++L N +
Sbjct: 17 LVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAI-PELTQRLDLQGNLLK 75
Query: 60 NL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXX 118
+ AF LT LD+ + ++ + F + LNL++N L+ L ++A G
Sbjct: 76 VIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGS 135
Query: 119 XXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
+ + TF L AL L+ ++N LV F+ L ++ L L +N++
Sbjct: 136 LRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALS 195
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+ L + L L L N +Q + L + L L+L +N + + +LP
Sbjct: 196 VLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPG 255
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LR L L + + A + L L L G
Sbjct: 256 LRELLLDGGALQALGPRAFAHCPRLHTLDLRG 287
Score = 66.1 bits (154), Expect = 3e-10
Identities = 64/255 (25%), Positives = 101/255 (39%), Gaps = 3/255 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C+C R +SC L+ VP + L++L N ++ AF L L
Sbjct: 396 CPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLH 455
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ + I +L + + +L LS+N L L A G +
Sbjct: 456 LQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGA 515
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
R L +L L +N + P +L+ + L N I ++ LG LE L
Sbjct: 516 ALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLH 575
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSL-PSLRHLDLSDNNMTLIPT 254
L N +++V L L L L L+ N + ++ F + SL+HL L+ + + I
Sbjct: 576 LDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICP 635
Query: 255 SALSKLS-NLSHLYL 268
A S L L L+L
Sbjct: 636 GAFSGLGPGLQSLHL 650
Score = 59.3 bits (137), Expect = 4e-08
Identities = 61/250 (24%), Positives = 96/250 (38%), Gaps = 5/250 (2%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L L L + + E L L L L +N + + +A L L YL L
Sbjct: 445 FPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYL 504
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
N QV L L L L L +N ++ + +LR + LS N +T + A
Sbjct: 505 ERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGA 564
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L L L+L D +LQ ++
Sbjct: 565 LGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLF 624
Query: 317 MNDNVKVREVPPRLFHG-NPKLTNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCS 375
+N + + ++ P F G P L +++++ N L L A + +L+ +++S NPF C+C
Sbjct: 625 LNSS-GLEQICPGAFSGLGPGLQSLHLQKNQLRALPALP-SLSQLELIDLSSNPFHCDCQ 682
Query: 376 LLWL--WKLG 383
LL L W G
Sbjct: 683 LLPLHRWLTG 692
Score = 56.4 bits (130), Expect = 3e-07
Identities = 54/243 (22%), Positives = 97/243 (39%), Gaps = 3/243 (1%)
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I F+ + L LD + + F L L +L+L +N + ++P L + L
Sbjct: 77 IPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSL 136
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L+L N ++++ L L L+L +N + + + F L +R L LS N +++
Sbjct: 137 RRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSV 196
Query: 252 IPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNIN 311
+ AL+ L L L L +
Sbjct: 197 LAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALP-G 255
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGNPFA 371
L+++ + D ++ + PR F P+L + ++ N L+TL P +L+ L + GNP
Sbjct: 256 LRELLL-DGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGP-GQLRRLRLQGNPLW 313
Query: 372 CNC 374
C C
Sbjct: 314 CGC 316
Score = 55.6 bits (128), Expect = 4e-07
Identities = 47/178 (26%), Positives = 69/178 (38%)
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
S+ + L+L N + + AF G I+ + L L L S+N+
Sbjct: 425 SDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQ 484
Query: 153 LVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL 212
L E L L L N L +P A L + L L L +N + +++ L
Sbjct: 485 LAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRT 544
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L+ + L+ N I V L L L N + +PT AL L L L LSG
Sbjct: 545 RALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSG 602
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 80.6 bits (190), Expect = 1e-14
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 1/216 (0%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF L +L +++N I L F+ ++ L L +N + R+ +
Sbjct: 168 LQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQR 227
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + Q + L +D NR+ TF SL +L
Sbjct: 228 LFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLF 287
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N I +P + +L LDLS N I ++S H LK L+ L+L++N + + +
Sbjct: 288 LPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKN 347
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F SL L+ LDL + I T + NLSH+Y
Sbjct: 348 QFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIY 383
Score = 71.3 bits (167), Expect = 8e-12
Identities = 54/199 (27%), Positives = 87/199 (43%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
+T+L + NKI L + F ++++ + L +N ++ + + AF G I+
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCIT 198
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
+ F+DL L L +N + F L+SL LS+ NN + +P +
Sbjct: 199 TLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQ 258
Query: 191 LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L ++DL N I+ ++ L L L N I V + F SL +L LDLS N +T
Sbjct: 259 LNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTIT 318
Query: 251 LIPTSALSKLSNLSHLYLS 269
+ L L L LS
Sbjct: 319 ELSPHLFKDLKLLQKLNLS 337
Score = 48.0 bits (109), Expect = 9e-05
Identities = 30/129 (23%), Positives = 54/129 (41%)
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRL 153
++ ++L N +K L F+ +I + +TF L L LD S+N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
P F+ L L+ L+L +N ++ + + L+ LDL I ++ +K
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMK 377
Query: 214 ELKHLDLNN 222
L H+ N
Sbjct: 378 NLSHIYFKN 386
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 43/94 (45%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L LD+S N I +L F+ ++ LNLS+N L L K+ F
Sbjct: 301 FSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL 360
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
EI NI+ + F+ + L + F N R ++ P
Sbjct: 361 ERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAP 394
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 31 SCANANLEIVPIQL---NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGS 86
S N LE +P Q+ P+ ++L N I L + F LTVL + N+I +
Sbjct: 239 SMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPE 298
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ F S + L+LS+N + L F + +H F L L+ L
Sbjct: 299 KTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSL 358
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRN 174
D + F+P+ +L + +N
Sbjct: 359 DLERIEIPNINTRMFQPMKNLSHIYFKN 386
Score = 41.9 bits (94), Expect = 0.006
Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 3/206 (1%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
+++ +LSL+ N I +P L+ + L N I+ +SR L L+ L LN+N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
I ++ F L L L L DN +T I + L++L L +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVN-NYLEALPKQMCAQ 255
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ + + F+ +L +++ N ++ VP + F L + + +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRN-QIGFVPEKTFSSLKNLGELDLSS 314
Query: 345 NALETLEASHF-PIDRLQELEISGNP 369
N + L F + LQ+L +S NP
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNP 340
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 80.6 bits (190), Expect = 1e-14
Identities = 61/216 (28%), Positives = 96/216 (44%), Gaps = 1/216 (0%)
Query: 53 LTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L HN I ++ AF L +L +++N I L F+ ++ L L +N + R+ +
Sbjct: 168 LQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQR 227
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F G + + Q + L +D NR+ TF SL +L
Sbjct: 228 LFTGLNSLFFLSMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLF 287
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N I +P + +L LDLS N I ++S H LK L+ L+L++N + + +
Sbjct: 288 LPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKN 347
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F SL L+ LDL + I T + NLSH+Y
Sbjct: 348 QFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIY 383
Score = 71.3 bits (167), Expect = 8e-12
Identities = 54/199 (27%), Positives = 87/199 (43%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
+T+L + NKI L + F ++++ + L +N ++ + + AF G I+
Sbjct: 139 VTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCIT 198
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIH 190
+ F+DL L L +N + F L+SL LS+ NN + +P +
Sbjct: 199 TLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMPQ 258
Query: 191 LEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L ++DL N I+ ++ L L L N I V + F SL +L LDLS N +T
Sbjct: 259 LNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTIT 318
Query: 251 LIPTSALSKLSNLSHLYLS 269
+ L L L LS
Sbjct: 319 ELSPHLFKDLKLLQKLNLS 337
Score = 48.0 bits (109), Expect = 9e-05
Identities = 30/129 (23%), Positives = 54/129 (41%)
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRL 153
++ ++L N +K L F+ +I + +TF L L LD S+N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
P F+ L L+ L+L +N ++ + + L+ LDL I ++ +K
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMK 377
Query: 214 ELKHLDLNN 222
L H+ N
Sbjct: 378 NLSHIYFKN 386
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 43/94 (45%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L LD+S N I +L F+ ++ LNLS+N L L K+ F
Sbjct: 301 FSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL 360
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEP 158
EI NI+ + F+ + L + F N R ++ P
Sbjct: 361 ERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAP 394
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 31 SCANANLEIVPIQL---NPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDISYNKILDLGS 86
S N LE +P Q+ P+ ++L N I L + F LTVL + N+I +
Sbjct: 239 SMVNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPE 298
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+ F S + L+LS+N + L F + +H F L L+ L
Sbjct: 299 KTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSL 358
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRN 174
D + F+P+ +L + +N
Sbjct: 359 DLERIEIPNINTRMFQPMKNLSHIYFKN 386
Score = 41.9 bits (94), Expect = 0.006
Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 3/206 (1%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
+++ +LSL+ N I +P L+ + L N I+ +SR L L+ L LN+N
Sbjct: 137 NNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNC 196
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
I ++ F L L L L DN +T I + L++L L +
Sbjct: 197 ITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVN-NYLEALPKQMCAQ 255
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ + + F+ +L +++ N ++ VP + F L + + +
Sbjct: 256 MPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRN-QIGFVPEKTFSSLKNLGELDLSS 314
Query: 345 NALETLEASHF-PIDRLQELEISGNP 369
N + L F + LQ+L +S NP
Sbjct: 315 NTITELSPHLFKDLKLLQKLNLSSNP 340
>AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein.
Length = 620
Score = 79.8 bits (188), Expect = 2e-14
Identities = 75/315 (23%), Positives = 128/315 (40%), Gaps = 5/315 (1%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
T+ +LD+ N+I L + F S + L L+ N + ++ AF
Sbjct: 71 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 130
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ I + F LS L + D S N++V F+ L +LK L + +N ++ I +
Sbjct: 131 LKLIPLGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 190
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSD-N 247
LE L L + + + L L L L L + I ++ F L L+ L++S
Sbjct: 191 NSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWP 250
Query: 248 NMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFV 307
+ + + L L NL+ L ++ I+
Sbjct: 251 YLDTMTPNCLYGL-NLTSLSIT-HCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLH 308
Query: 308 DNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEIS 366
+ + LQ+I + ++ V P F G L + + N L TLE S F + L+ L +
Sbjct: 309 ELLRLQEIQLVGG-QLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILD 367
Query: 367 GNPFACNCSLLWLWK 381
NP AC+C LLW+++
Sbjct: 368 SNPLACDCRLLWVFR 382
Score = 74.9 bits (176), Expect = 7e-13
Identities = 68/261 (26%), Positives = 113/261 (43%), Gaps = 3/261 (1%)
Query: 11 AAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYT 69
+ + T CP RC C RA C VP + E L++L N I L F +
Sbjct: 36 SGSATGCPPRCECSAQDRAVLCHRKCFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFP 95
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
L L+++ N + + F + +R L L +N LK + F G +I
Sbjct: 96 HLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKQDISENKI 155
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+ F+DL L+ L+ +N LV F L+SL+ L+L ++ IP+ L +
Sbjct: 156 VILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLH 215
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN-NIIESVDQLGFHSLPSLRHLDLSDNN 248
L L L I + + L LK L++++ ++++ + L +L L ++ N
Sbjct: 216 GLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTMTPNCLYGL-NLTSLSITHCN 274
Query: 249 MTLIPTSALSKLSNLSHLYLS 269
+T +P A+ L L L LS
Sbjct: 275 LTAVPYLAVRHLVYLRFLNLS 295
Score = 56.4 bits (130), Expect = 3e-07
Identities = 49/209 (23%), Positives = 89/209 (42%)
Query: 62 LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXX 121
L F + LT DIS NKI+ L F+ ++ L + +N L + AF G
Sbjct: 136 LGVFTGLSNLTKQDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLEQ 195
Query: 122 XXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIP 181
+++I + L L L + + +F+ L LK+L + + LD
Sbjct: 196 LTLEKCNLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEISHWPYLDTM 255
Query: 182 SANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRH 241
+ N + ++L L ++ + V + L L+ L+L+ N I +++ H L L+
Sbjct: 256 TPNCLYGLNLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQE 315
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+ L + ++ A L+ L L +SG
Sbjct: 316 IQLVGGQLAVVEPYAFRGLNYLRVLNVSG 344
Score = 36.7 bits (81), Expect = 0.22
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L++ + + L + +R LNLS N + ++
Sbjct: 258 NCLYGLNL-TSLSITHCNLTAVPYLAVRHLVY---LRFLNLSYNPISTIEGSMLHELLRL 313
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+++ + FR L+ L L+ S N+L T E F + +L+ L L +N +
Sbjct: 314 QEIQLVGGQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 371
>Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 3e-14
Identities = 97/387 (25%), Positives = 144/387 (37%), Gaps = 56/387 (14%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF 65
W+ A CP C C R S C A L VP +L EA ++L N + L
Sbjct: 22 WAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFL---- 77
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGX-XXXXXXXX 124
G F + +R L+L +N L + AF G
Sbjct: 78 -------------------GERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLA 118
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ +H +TF LS L RLD + RL + L +L+ L+ +N +P A
Sbjct: 119 HNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL 178
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
G + +L + L I+ V+ L L+ L+ L L N + +V F L HL L
Sbjct: 179 RG-LANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLL 237
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
+DN + +P A L L L L G +R+
Sbjct: 238 NDNLLAELPADAFRGLRRLRTLNLGG-------------------------NALDRVARA 272
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQEL 363
F D L+ ++++ N + V F L +++ N L L F P L L
Sbjct: 273 WFADLAELELLYLDRN-SIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRL 331
Query: 364 EISGNPFACNCSLLWL--WKLGKDSET 388
+ NP+ C+C L WL W G T
Sbjct: 332 FLFRNPWCCDCRLEWLRDWMEGSGRVT 358
>BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 3e-14
Identities = 97/387 (25%), Positives = 144/387 (37%), Gaps = 56/387 (14%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF 65
W+ A CP C C R S C A L VP +L EA ++L N + L
Sbjct: 22 WAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFL---- 77
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGX-XXXXXXXX 124
G F + +R L+L +N L + AF G
Sbjct: 78 -------------------GERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLA 118
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ +H +TF LS L RLD + RL + L +L+ L+ +N +P A
Sbjct: 119 HNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL 178
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
G + +L + L I+ V+ L L+ L+ L L N + +V F L HL L
Sbjct: 179 RG-LANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLL 237
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
+DN + +P A L L L L G +R+
Sbjct: 238 NDNLLAELPADAFRGLRRLRTLNLGG-------------------------NALDRVARA 272
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQEL 363
F D L+ ++++ N + V F L +++ N L L F P L L
Sbjct: 273 WFADLAELELLYLDRN-SIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRL 331
Query: 364 EISGNPFACNCSLLWL--WKLGKDSET 388
+ NP+ C+C L WL W G T
Sbjct: 332 FLFRNPWCCDCRLEWLRDWMEGSGRVT 358
>AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat
protein protein.
Length = 481
Score = 79.4 bits (187), Expect = 3e-14
Identities = 97/387 (25%), Positives = 144/387 (37%), Gaps = 56/387 (14%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF 65
W+ A CP C C R S C A L VP +L EA ++L N + L
Sbjct: 22 WAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFL---- 77
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGX-XXXXXXXX 124
G F + +R L+L +N L + AF G
Sbjct: 78 -------------------GERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLA 118
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ +H +TF LS L RLD + RL + L +L+ L+ +N +P A
Sbjct: 119 HNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL 178
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
G + +L + L I+ V+ L L+ L+ L L N + +V F L HL L
Sbjct: 179 RG-LANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLL 237
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
+DN + +P A L L L L G +R+
Sbjct: 238 NDNLLAELPADAFRGLRRLRTLNLGG-------------------------NALDRVARA 272
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQEL 363
F D L+ ++++ N + V F L +++ N L L F P L L
Sbjct: 273 WFADLAELELLYLDRN-SIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRL 331
Query: 364 EISGNPFACNCSLLWL--WKLGKDSET 388
+ NP+ C+C L WL W G T
Sbjct: 332 FLFRNPWCCDCRLEWLRDWMEGSGRVT 358
>AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein.
Length = 481
Score = 79.4 bits (187), Expect = 3e-14
Identities = 97/387 (25%), Positives = 144/387 (37%), Gaps = 56/387 (14%)
Query: 8 WSAAAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAF 65
W+ A CP C C R S C A L VP +L EA ++L N + L
Sbjct: 22 WAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFL---- 77
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGX-XXXXXXXX 124
G F + +R L+L +N L + AF G
Sbjct: 78 -------------------GERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLA 118
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSAN 184
++ +H +TF LS L RLD + RL + L +L+ L+ +N +P A
Sbjct: 119 HNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGAL 178
Query: 185 LGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL 244
G + +L + L I+ V+ L L+ L+ L L N + +V F L HL L
Sbjct: 179 RG-LANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLL 237
Query: 245 SDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSR 304
+DN + +P A L L L L G +R+
Sbjct: 238 NDNLLAELPADAFRGLRRLRTLNLGG-------------------------NALDRVARA 272
Query: 305 AFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQEL 363
F D L+ ++++ N + V F L +++ N L L F P L L
Sbjct: 273 WFADLAELELLYLDRN-SIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRL 331
Query: 364 EISGNPFACNCSLLWL--WKLGKDSET 388
+ NP+ C+C L WL W G T
Sbjct: 332 FLFRNPWCCDCRLEWLRDWMEGSGRVT 358
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 79.0 bits (186), Expect = 4e-14
Identities = 72/316 (22%), Positives = 121/316 (38%), Gaps = 4/316 (1%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + VL + N I E + + L+ S N + +
Sbjct: 69 NLSSDTQVLLLQSNNIAKTVDE-LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLE 127
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + +DLS L+ L ++N++ T F L +L L L +N + I S
Sbjct: 128 ENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWF 187
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+LE L + EN + + L L+ L L + + L SL L
Sbjct: 188 DSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFY 247
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRA 305
DN + +P AL K+ NL L L+ +D A
Sbjct: 248 DNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYA 307
Query: 306 FVDNI-NLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRLQEL 363
+DN+ L K+ +N K+ + F P L ++ + NNAL + + + + L+E+
Sbjct: 308 -LDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 364 EISGNPFACNCSLLWL 379
I NP C+C + W+
Sbjct: 367 SIHSNPLRCDCVIHWI 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 3/217 (1%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
+ HN I + +AF L L ++ NK+ + S F+S + L + N + +
Sbjct: 150 INHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDM 209
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F +++I L +LE L F +N+LV + + +LK L
Sbjct: 210 NFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLD 269
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSE-NLIQQVSRHGLPFLKELKHLDLNNNI-IESVD 229
L N I I + ++ L+ L ++ + V R+ L L EL L+ NN + +
Sbjct: 270 LNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIH 329
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+L F S+P+L L L++N + I + L NL +
Sbjct: 330 RLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Score = 54.8 bits (126), Expect = 8e-07
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L +L I N ++ + NF+ + +R L L+ +L + +A VG
Sbjct: 187 FDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSF 246
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRN-NSILDIPSA 183
++ + + + L+ LD + N + + F+ + LK L + N ++ +
Sbjct: 247 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 306
Query: 184 NLGFVIHLEYLDLSEN-LIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL 242
L + L L+ + N + + R + L+ L LNNN + ++ Q SLP+LR +
Sbjct: 307 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 243 DLSDN 247
+ N
Sbjct: 367 SIHSN 371
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 79.0 bits (186), Expect = 4e-14
Identities = 72/316 (22%), Positives = 121/316 (38%), Gaps = 4/316 (1%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + VL + N I E + + L+ S N + +
Sbjct: 69 NLSSDTQVLLLQSNNIAKTVDE-LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLE 127
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + +DLS L+ L ++N++ T F L +L L L +N + I S
Sbjct: 128 ENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWF 187
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+LE L + EN + + L L+ L L + + L SL L
Sbjct: 188 DSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFY 247
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRA 305
DN + +P AL K+ NL L L+ +D A
Sbjct: 248 DNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYA 307
Query: 306 FVDNI-NLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRLQEL 363
+DN+ L K+ +N K+ + F P L ++ + NNAL + + + + L+E+
Sbjct: 308 -LDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 364 EISGNPFACNCSLLWL 379
I NP C+C + W+
Sbjct: 367 SIHSNPLRCDCVIHWI 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 3/217 (1%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
+ HN I + +AF L L ++ NK+ + S F+S + L + N + +
Sbjct: 150 INHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDM 209
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F +++I L +LE L F +N+LV + + +LK L
Sbjct: 210 NFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLD 269
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSE-NLIQQVSRHGLPFLKELKHLDLNNNI-IESVD 229
L N I I + ++ L+ L ++ + V R+ L L EL L+ NN + +
Sbjct: 270 LNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIH 329
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+L F S+P+L L L++N + I + L NL +
Sbjct: 330 RLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Score = 54.8 bits (126), Expect = 8e-07
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L +L I N ++ + NF+ + +R L L+ +L + +A VG
Sbjct: 187 FDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSF 246
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRN-NSILDIPSA 183
++ + + + L+ LD + N + + F+ + LK L + N ++ +
Sbjct: 247 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 306
Query: 184 NLGFVIHLEYLDLSEN-LIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL 242
L + L L+ + N + + R + L+ L LNNN + ++ Q SLP+LR +
Sbjct: 307 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 243 DLSDN 247
+ N
Sbjct: 367 SIHSN 371
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 79.0 bits (186), Expect = 4e-14
Identities = 72/316 (22%), Positives = 121/316 (38%), Gaps = 4/316 (1%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + VL + N I E + + L+ S N + +
Sbjct: 83 NLSSDTQVLLLQSNNIAKTVDE-LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLE 141
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + +DLS L+ L ++N++ T F L +L L L +N + I S
Sbjct: 142 ENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWF 201
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+LE L + EN + + L L+ L L + + L SL L
Sbjct: 202 DSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFY 261
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRA 305
DN + +P AL K+ NL L L+ +D A
Sbjct: 262 DNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYA 321
Query: 306 FVDNI-NLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRLQEL 363
+DN+ L K+ +N K+ + F P L ++ + NNAL + + + + L+E+
Sbjct: 322 -LDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 380
Query: 364 EISGNPFACNCSLLWL 379
I NP C+C + W+
Sbjct: 381 SIHSNPLRCDCVIHWI 396
Score = 65.3 bits (152), Expect = 5e-10
Identities = 54/217 (24%), Positives = 94/217 (43%), Gaps = 3/217 (1%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
+ HN I + +AF L L ++ NK+ + S F+S + L + N + +
Sbjct: 164 INHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDM 223
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F +++I L +LE L F +N+LV + + +LK L
Sbjct: 224 NFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLD 283
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSE-NLIQQVSRHGLPFLKELKHLDLNNNI-IESVD 229
L N I I + ++ L+ L ++ + V R+ L L EL L+ NN + +
Sbjct: 284 LNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIH 343
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+L F S+P+L L L++N + I + L NL +
Sbjct: 344 RLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 380
Score = 54.8 bits (126), Expect = 8e-07
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L +L I N ++ + NF+ + +R L L+ +L + +A VG
Sbjct: 201 FDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSF 260
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRN-NSILDIPSA 183
++ + + + L+ LD + N + + F+ + LK L + N ++ +
Sbjct: 261 YDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 320
Query: 184 NLGFVIHLEYLDLSEN-LIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL 242
L + L L+ + N + + R + L+ L LNNN + ++ Q SLP+LR +
Sbjct: 321 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 380
Query: 243 DLSDN 247
+ N
Sbjct: 381 SIHSN 385
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 78.2 bits (184), Expect = 7e-14
Identities = 56/182 (30%), Positives = 87/182 (47%), Gaps = 8/182 (4%)
Query: 1 MVLF-AWTWSAAAAKTL---CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHN 56
+VLF AW A A+ CP RC+C C + LE VP + P+ ++++L N
Sbjct: 33 LVLFCAWGTLAVVAQKPGAGCPSRCLCFRT--TVRCMHLLLEAVPA-VAPQTSILDLRFN 89
Query: 57 AIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVG 115
I + AF L L ++ N+I + S FE +++L L N ++ +D+ AF G
Sbjct: 90 RIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKG 149
Query: 116 XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I + +F+ L LERL NNR+ P TF L S+K L L +N
Sbjct: 150 LASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSN 209
Query: 176 SI 177
++
Sbjct: 210 TL 211
Score = 69.3 bits (162), Expect = 3e-11
Identities = 43/123 (34%), Positives = 61/123 (49%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD NR+ +P F L +L L L NN I IPS + +L+YL L +N IQ +
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
R L L+ L L+ N IE++D F LP L L L +N +T + + L ++
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 266 LYL 268
L L
Sbjct: 204 LRL 206
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/132 (28%), Positives = 65/132 (49%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
Q ++LD+ +N+I ++ F + L L+NN +KR+ AF EI
Sbjct: 80 QTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEI 139
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+I Q F+ L++LE+L N++ T +P++F+ L L+ L L NN I + +
Sbjct: 140 QSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLE 199
Query: 190 HLEYLDLSENLI 201
++ L L N +
Sbjct: 200 SMKRLRLDSNTL 211
Score = 52.0 bits (119), Expect = 5e-06
Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 14/195 (7%)
Query: 237 PSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
P LDL N + I A +L NL+ L L+
Sbjct: 79 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 138
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP 356
+ ID +AF +L++++++ N ++ + P F PKL +++ NN + L F
Sbjct: 139 I-QSIDRQAFKGLASLEQLYLHFN-QIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFN 196
Query: 357 -IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQL 415
++ ++ L + N C+C +LWL L K T +SGN+ +Y P ++
Sbjct: 197 HLESMKRLRLDSNTLHCDCEILWLADLLK----TYAESGNAQAAAICEY-------PRRI 245
Query: 416 KGMLFVQIPESEFGC 430
+G I E C
Sbjct: 246 QGRSVATITPEELNC 260
Score = 50.4 bits (115), Expect = 2e-05
Identities = 38/121 (31%), Positives = 53/121 (43%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I FR L L L +NN++ FE L +LK L L N I I +
Sbjct: 91 IREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGL 150
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L N I+ + L +L+ L L+NN I + F+ L S++ L L N
Sbjct: 151 ASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNT 210
Query: 249 M 249
+
Sbjct: 211 L 211
Score = 48.0 bits (109), Expect = 9e-05
Identities = 32/100 (32%), Positives = 48/100 (48%)
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
IL LR N I +I + +L L L+ N I+++ L+ LK+L L N I+S+
Sbjct: 83 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 142
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
D+ F L SL L L N + + + L L L+L
Sbjct: 143 DRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFL 182
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 78.2 bits (184), Expect = 7e-14
Identities = 56/182 (30%), Positives = 87/182 (47%), Gaps = 8/182 (4%)
Query: 1 MVLF-AWTWSAAAAKTL---CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHN 56
+VLF AW A A+ CP RC+C C + LE VP + P+ ++++L N
Sbjct: 11 LVLFCAWGTLAVVAQKPGAGCPSRCLCFRT--TVRCMHLLLEAVPA-VAPQTSILDLRFN 67
Query: 57 AIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVG 115
I + AF L L ++ N+I + S FE +++L L N ++ +D+ AF G
Sbjct: 68 RIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKG 127
Query: 116 XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I + +F+ L LERL NNR+ P TF L S+K L L +N
Sbjct: 128 LASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSN 187
Query: 176 SI 177
++
Sbjct: 188 TL 189
Score = 69.3 bits (162), Expect = 3e-11
Identities = 43/123 (34%), Positives = 61/123 (49%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD NR+ +P F L +L L L NN I IPS + +L+YL L +N IQ +
Sbjct: 62 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 121
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
R L L+ L L+ N IE++D F LP L L L +N +T + + L ++
Sbjct: 122 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 181
Query: 266 LYL 268
L L
Sbjct: 182 LRL 184
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/132 (28%), Positives = 65/132 (49%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
Q ++LD+ +N+I ++ F + L L+NN +KR+ AF EI
Sbjct: 58 QTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEI 117
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+I Q F+ L++LE+L N++ T +P++F+ L L+ L L NN I + +
Sbjct: 118 QSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLE 177
Query: 190 HLEYLDLSENLI 201
++ L L N +
Sbjct: 178 SMKRLRLDSNTL 189
Score = 52.0 bits (119), Expect = 5e-06
Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 14/195 (7%)
Query: 237 PSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
P LDL N + I A +L NL+ L L+
Sbjct: 57 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 116
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP 356
+ ID +AF +L++++++ N ++ + P F PKL +++ NN + L F
Sbjct: 117 I-QSIDRQAFKGLASLEQLYLHFN-QIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFN 174
Query: 357 -IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQL 415
++ ++ L + N C+C +LWL L K T +SGN+ +Y P ++
Sbjct: 175 HLESMKRLRLDSNTLHCDCEILWLADLLK----TYAESGNAQAAAICEY-------PRRI 223
Query: 416 KGMLFVQIPESEFGC 430
+G I E C
Sbjct: 224 QGRSVATITPEELNC 238
Score = 50.4 bits (115), Expect = 2e-05
Identities = 38/121 (31%), Positives = 53/121 (43%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I FR L L L +NN++ FE L +LK L L N I I +
Sbjct: 69 IREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGL 128
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L N I+ + L +L+ L L+NN I + F+ L S++ L L N
Sbjct: 129 ASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNT 188
Query: 249 M 249
+
Sbjct: 189 L 189
Score = 48.0 bits (109), Expect = 9e-05
Identities = 32/100 (32%), Positives = 48/100 (48%)
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
IL LR N I +I + +L L L+ N I+++ L+ LK+L L N I+S+
Sbjct: 61 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 120
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
D+ F L SL L L N + + + L L L+L
Sbjct: 121 DRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFL 160
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 78.2 bits (184), Expect = 7e-14
Identities = 56/182 (30%), Positives = 87/182 (47%), Gaps = 8/182 (4%)
Query: 1 MVLF-AWTWSAAAAKTL---CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHN 56
+VLF AW A A+ CP RC+C C + LE VP + P+ ++++L N
Sbjct: 33 LVLFCAWGTLAVVAQKPGAGCPSRCLCFRT--TVRCMHLLLEAVPA-VAPQTSILDLRFN 89
Query: 57 AIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVG 115
I + AF L L ++ N+I + S FE +++L L N ++ +D+ AF G
Sbjct: 90 RIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKG 149
Query: 116 XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I + +F+ L LERL NNR+ P TF L S+K L L +N
Sbjct: 150 LASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSN 209
Query: 176 SI 177
++
Sbjct: 210 TL 211
Score = 69.3 bits (162), Expect = 3e-11
Identities = 43/123 (34%), Positives = 61/123 (49%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD NR+ +P F L +L L L NN I IPS + +L+YL L +N IQ +
Sbjct: 84 LDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSID 143
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
R L L+ L L+ N IE++D F LP L L L +N +T + + L ++
Sbjct: 144 RQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKR 203
Query: 266 LYL 268
L L
Sbjct: 204 LRL 206
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/132 (28%), Positives = 65/132 (49%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
Q ++LD+ +N+I ++ F + L L+NN +KR+ AF EI
Sbjct: 80 QTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEI 139
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+I Q F+ L++LE+L N++ T +P++F+ L L+ L L NN I + +
Sbjct: 140 QSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLE 199
Query: 190 HLEYLDLSENLI 201
++ L L N +
Sbjct: 200 SMKRLRLDSNTL 211
Score = 52.0 bits (119), Expect = 5e-06
Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 14/195 (7%)
Query: 237 PSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
P LDL N + I A +L NL+ L L+
Sbjct: 79 PQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 138
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP 356
+ ID +AF +L++++++ N ++ + P F PKL +++ NN + L F
Sbjct: 139 I-QSIDRQAFKGLASLEQLYLHFN-QIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFN 196
Query: 357 -IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQL 415
++ ++ L + N C+C +LWL L K T +SGN+ +Y P ++
Sbjct: 197 HLESMKRLRLDSNTLHCDCEILWLADLLK----TYAESGNAQAAAICEY-------PRRI 245
Query: 416 KGMLFVQIPESEFGC 430
+G I E C
Sbjct: 246 QGRSVATITPEELNC 260
Score = 50.4 bits (115), Expect = 2e-05
Identities = 38/121 (31%), Positives = 53/121 (43%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I FR L L L +NN++ FE L +LK L L N I I +
Sbjct: 91 IREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDRQAFKGL 150
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L N I+ + L +L+ L L+NN I + F+ L S++ L L N
Sbjct: 151 ASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRLRLDSNT 210
Query: 249 M 249
+
Sbjct: 211 L 211
Score = 48.0 bits (109), Expect = 9e-05
Identities = 32/100 (32%), Positives = 48/100 (48%)
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
IL LR N I +I + +L L L+ N I+++ L+ LK+L L N I+S+
Sbjct: 83 ILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSI 142
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
D+ F L SL L L N + + + L L L+L
Sbjct: 143 DRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFL 182
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 77.0 bits (181), Expect = 2e-13
Identities = 71/316 (22%), Positives = 121/316 (38%), Gaps = 4/316 (1%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + VL + N I E + + L+ S N + +
Sbjct: 69 NLSSDTQVLLLQSNNIAKTVDE-LQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLE 127
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + +DLS L+ L ++N++ T F L +L L L +N + I S
Sbjct: 128 ENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWF 187
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
+LE L + EN + + L L+ L L + + L SL L
Sbjct: 188 DSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFY 247
Query: 246 DNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRA 305
DN + +P AL K+ +L L L+ +D A
Sbjct: 248 DNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYA 307
Query: 306 FVDNI-NLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRLQEL 363
+DN+ L K+ +N K+ + F P L ++ + NNAL + + + + L+E+
Sbjct: 308 -LDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 364 EISGNPFACNCSLLWL 379
I NP C+C + W+
Sbjct: 367 SIHSNPLRCDCVIHWI 382
Score = 66.5 bits (155), Expect = 2e-10
Identities = 55/217 (25%), Positives = 94/217 (43%), Gaps = 3/217 (1%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
+ HN I + +AF L L ++ NK+ + S F+S + L + N + +
Sbjct: 150 INHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDM 209
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F +++I L +LE L F +N+LV + + SLK L
Sbjct: 210 NFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLD 269
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSE-NLIQQVSRHGLPFLKELKHLDLNNNI-IESVD 229
L N I I + ++ L+ L ++ + V R+ L L EL L+ NN + +
Sbjct: 270 LNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIH 329
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
+L F S+P+L L L++N + I + L NL +
Sbjct: 330 RLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Score = 56.0 bits (129), Expect = 3e-07
Identities = 41/185 (22%), Positives = 82/185 (44%), Gaps = 2/185 (1%)
Query: 65 FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXX 124
F+ L +L I N ++ + NF+ + +R L L+ +L + +A VG
Sbjct: 187 FDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSF 246
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRN-NSILDIPSA 183
++ + + + +L+ LD + N + + F+ + LK L + N ++ +
Sbjct: 247 YDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRY 306
Query: 184 NLGFVIHLEYLDLSEN-LIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL 242
L + L L+ + N + + R + L+ L LNNN + ++ Q SLP+LR +
Sbjct: 307 ALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTVESLPNLREI 366
Query: 243 DLSDN 247
+ N
Sbjct: 367 SIHSN 371
>BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 76.2 bits (179), Expect = 3e-13
Identities = 69/279 (24%), Positives = 115/279 (41%), Gaps = 26/279 (9%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
LNL N L ++F +I + FR L L L S+N +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L+ L L L +N + ++P L +++L L L+ N I+++ K+L+
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXX 277
L L+ N + S+ + +L + N ++ P++ALSKL + L LS
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS-------- 227
Query: 278 XXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKL 337
R ++DN NL+K +D F G L
Sbjct: 228 ------HNPLKSIPDNAFQSFGRYLETLWLDNTNLEK--FSDGA---------FLGVTTL 270
Query: 338 TNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCSL 376
+++++NN L L S+FP D L+ L ++ NP+ C C L
Sbjct: 271 KHVHLENNRLNQL-PSNFPFDSLETLALTNNPWKCTCQL 308
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/258 (21%), Positives = 106/258 (41%), Gaps = 3/258 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQL 71
A CP C C L+ C L+ +P +++ + L+NL N L +F L
Sbjct: 19 ALAACPQNCHCHSDLQHVICDKVGLQKIP-KVSEKTKLLNLQRNNFPVLAANSFRAMPNL 77
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L + + +I ++ + F ++ +L LS+N ++ L AF +++
Sbjct: 78 VSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTE 137
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ L L L +NN++ F+ L+ L L N++ + L V +L
Sbjct: 138 LPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENL 197
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS-LRHLDLSDNNMT 250
+ N + L L+ ++ L L++N ++S+ F S L L L + N+
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257
Query: 251 LIPTSALSKLSNLSHLYL 268
A ++ L H++L
Sbjct: 258 KFSDGAFLGVTTLKHVHL 275
>BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 76.2 bits (179), Expect = 3e-13
Identities = 69/279 (24%), Positives = 115/279 (41%), Gaps = 26/279 (9%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
LNL N L ++F +I + FR L L L S+N +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L+ L L L +N + ++P L +++L L L+ N I+++ K+L+
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXX 277
L L+ N + S+ + +L + N ++ P++ALSKL + L LS
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS-------- 227
Query: 278 XXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKL 337
R ++DN NL+K +D F G L
Sbjct: 228 ------HNPLKSIPDNAFQSFGRYLETLWLDNTNLEK--FSDGA---------FLGVTTL 270
Query: 338 TNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCSL 376
+++++NN L L S+FP D L+ L ++ NP+ C C L
Sbjct: 271 KHVHLENNRLNQL-PSNFPFDSLETLALTNNPWKCTCQL 308
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/258 (21%), Positives = 106/258 (41%), Gaps = 3/258 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQL 71
A CP C C L+ C L+ +P +++ + L+NL N L +F L
Sbjct: 19 ALAACPQNCHCHSDLQHVICDKVGLQKIP-KVSEKTKLLNLQRNNFPVLAANSFRAMPNL 77
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L + + +I ++ + F ++ +L LS+N ++ L AF +++
Sbjct: 78 VSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTE 137
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ L L L +NN++ F+ L+ L L N++ + L V +L
Sbjct: 138 LPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENL 197
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS-LRHLDLSDNNMT 250
+ N + L L+ ++ L L++N ++S+ F S L L L + N+
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257
Query: 251 LIPTSALSKLSNLSHLYL 268
A ++ L H++L
Sbjct: 258 KFSDGAFLGVTTLKHVHL 275
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 76.2 bits (179), Expect = 3e-13
Identities = 66/247 (26%), Positives = 102/247 (41%), Gaps = 4/247 (1%)
Query: 24 DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILD 83
DD A N + VP+Q + ++ NL ++ + +T + + +N I
Sbjct: 51 DDCGNQADEDNCVVGSVPVQCLCQGLELDCDET---NLRAVPSVSSNVTAMSLQWNLIRK 107
Query: 84 LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSAL 143
L + F++ +++ L L NN + + AF G I+ + F DL L
Sbjct: 108 LPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRL 167
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL-GFVIHLEYLDLSENLIQ 202
E L +N L P TF L+SL +L L NN + +P L + L +LDL N I
Sbjct: 168 EWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIH 227
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ L L + N I +++ F L L LDL N + +P L
Sbjct: 228 NLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKE 287
Query: 263 LSHLYLS 269
LS L LS
Sbjct: 288 LSQLNLS 294
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/217 (27%), Positives = 93/217 (42%), Gaps = 2/217 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L +N I ++ +YAF LT L +S+N+I L FE + L + +N L R+
Sbjct: 124 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 183
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTF-RDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
F G ++ + + + + L LD N + TF S+L +L
Sbjct: 184 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 243
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
+R N I + + L+ LDL N I+ + LKEL L+L+ N I+ +
Sbjct: 244 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 303
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F L L+ L L ++ I L NLSH+Y
Sbjct: 304 NQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIY 340
>AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 76.2 bits (179), Expect = 3e-13
Identities = 69/279 (24%), Positives = 115/279 (41%), Gaps = 26/279 (9%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
LNL N L ++F +I + FR L L L S+N +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLR 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L+ L L L +N + ++P L +++L L L+ N I+++ K+L+
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRW 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXX 277
L L+ N + S+ + +L + N ++ P++ALSKL + L LS
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS-------- 227
Query: 278 XXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKL 337
R ++DN NL+K +D F G L
Sbjct: 228 ------HNPLKSIPDNAFQSFGRYLETLWLDNTNLEK--FSDGA---------FLGVTTL 270
Query: 338 TNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCSL 376
+++++NN L L S+FP D L+ L ++ NP+ C C L
Sbjct: 271 KHVHLENNRLNQL-PSNFPFDSLETLALTNNPWKCTCQL 308
Score = 67.3 bits (157), Expect = 1e-10
Identities = 56/258 (21%), Positives = 106/258 (41%), Gaps = 3/258 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQL 71
A CP C C L+ C L+ +P +++ + L+NL N L +F L
Sbjct: 19 ALAACPQNCHCHSDLQHVICDKVGLQKIP-KVSEKTKLLNLQRNNFPVLAANSFRAMPNL 77
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L + + +I ++ + F ++ +L LS+N ++ L AF +++
Sbjct: 78 VSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTE 137
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ L L L +NN++ F+ L+ L L N++ + L V +L
Sbjct: 138 LPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENL 197
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS-LRHLDLSDNNMT 250
+ N + L L+ ++ L L++N ++S+ F S L L L + N+
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257
Query: 251 LIPTSALSKLSNLSHLYL 268
A ++ L H++L
Sbjct: 258 KFSDGAFLGVTTLKHVHL 275
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 75.8 bits (178), Expect = 4e-13
Identities = 45/134 (33%), Positives = 70/134 (52%)
Query: 135 QTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
Q+F ++ L+RL S++ + P TF L LK L L N I +P A L ++ LE L
Sbjct: 68 QSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQL 127
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
L N ++ + ++ L L+ L LN N ++ + F +L +L+ LDLS NN+T +P
Sbjct: 128 FLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPK 187
Query: 255 SALSKLSNLSHLYL 268
L + L L L
Sbjct: 188 GLLGAQAKLERLLL 201
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/255 (25%), Positives = 101/255 (39%), Gaps = 5/255 (1%)
Query: 17 CPVRCMC--DDALRAASCANANLEIVPIQLN-PEATLMNLTHNAIDNLLYAFNLYTQLTV 73
CP C C DA + + A + + + N L + + + +F+ T L
Sbjct: 21 CPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQS--QSFSGMTVLQR 78
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L IS + I + F +++ L LS N + L + I
Sbjct: 79 LMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGID 138
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ L L+ L + N+L F L +LK+L L N++ +P LG LE
Sbjct: 139 QNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLER 198
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + + L L L L + N I S+ F LP+L L LS N++ +P
Sbjct: 199 LLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLP 258
Query: 254 TSALSKLSNLSHLYL 268
++ NL+ L L
Sbjct: 259 SALFLHSHNLTLLTL 273
Score = 61.7 bits (143), Expect = 7e-09
Identities = 56/254 (22%), Positives = 108/254 (42%), Gaps = 2/254 (0%)
Query: 84 LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSAL 143
L S++F + ++ L +S++ + + F +I+++ + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
E+L +N L + F+ L +L+ L+L N + +P++ + +L+ LDLS N +
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + L +L+ L L++N + S+D +SL +L L N++ I A +L NL
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 264 SHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKV 323
S L LS E + F + LQ++W+N ++
Sbjct: 245 SSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAE-LPGVLFGEMGGLQELWLN-RTQL 302
Query: 324 REVPPRLFHGNPKL 337
R +P F +L
Sbjct: 303 RTLPAAAFRNLSRL 316
Score = 35.5 bits (78), Expect = 0.50
Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 4/175 (2%)
Query: 49 TLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLS-NNFLK 106
TL+ L N + L F L L ++ ++ L + F + S +R+L ++ + L
Sbjct: 269 TLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLS 328
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L + AF G ++ + R L L ++ NRL F LSS
Sbjct: 329 ALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSS 388
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK-HLDL 220
L+ + L +N + +P G + L + L N + G PFL L+ HL L
Sbjct: 389 LESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLG-PFLGWLRQHLGL 442
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 75.8 bits (178), Expect = 4e-13
Identities = 45/134 (33%), Positives = 70/134 (52%)
Query: 135 QTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYL 194
Q+F ++ L+RL S++ + P TF L LK L L N I +P A L ++ LE L
Sbjct: 68 QSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQL 127
Query: 195 DLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPT 254
L N ++ + ++ L L+ L LN N ++ + F +L +L+ LDLS NN+T +P
Sbjct: 128 FLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPK 187
Query: 255 SALSKLSNLSHLYL 268
L + L L L
Sbjct: 188 GLLGAQAKLERLLL 201
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/255 (25%), Positives = 101/255 (39%), Gaps = 5/255 (1%)
Query: 17 CPVRCMC--DDALRAASCANANLEIVPIQLN-PEATLMNLTHNAIDNLLYAFNLYTQLTV 73
CP C C DA + + A + + + N L + + + +F+ T L
Sbjct: 21 CPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQS--QSFSGMTVLQR 78
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L IS + I + F +++ L LS N + L + I
Sbjct: 79 LMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGID 138
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ L L+ L + N+L F L +LK+L L N++ +P LG LE
Sbjct: 139 QNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLER 198
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N + + L L L L + N I S+ F LP+L L LS N++ +P
Sbjct: 199 LLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLP 258
Query: 254 TSALSKLSNLSHLYL 268
++ NL+ L L
Sbjct: 259 SALFLHSHNLTLLTL 273
Score = 61.7 bits (143), Expect = 7e-09
Identities = 56/254 (22%), Positives = 108/254 (42%), Gaps = 2/254 (0%)
Query: 84 LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSAL 143
L S++F + ++ L +S++ + + F +I+++ + L
Sbjct: 65 LQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
E+L +N L + F+ L +L+ L+L N + +P++ + +L+ LDLS N +
Sbjct: 125 EQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTH 184
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + L +L+ L L++N + S+D +SL +L L N++ I A +L NL
Sbjct: 185 LPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNL 244
Query: 264 SHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKV 323
S L LS E + F + LQ++W+N ++
Sbjct: 245 SSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAE-LPGVLFGEMGGLQELWLN-RTQL 302
Query: 324 REVPPRLFHGNPKL 337
R +P F +L
Sbjct: 303 RTLPAAAFRNLSRL 316
Score = 35.5 bits (78), Expect = 0.50
Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 4/175 (2%)
Query: 49 TLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLS-NNFLK 106
TL+ L N + L F L L ++ ++ L + F + S +R+L ++ + L
Sbjct: 269 TLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLS 328
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L + AF G ++ + R L L ++ NRL F LSS
Sbjct: 329 ALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSS 388
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK-HLDL 220
L+ + L +N + +P G + L + L N + G PFL L+ HL L
Sbjct: 389 LESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLG-PFLGWLRQHLGL 442
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 75.8 bits (178), Expect = 4e-13
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL ++ + +T + + +N I L + F++ +++ L L NN + + AF G
Sbjct: 117 NLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSL 176
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I+ + F DL LE L +N L P TF L+SL +L L NN +
Sbjct: 177 TKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTR 236
Query: 180 IPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+P L + L +LDL N I + L L + N I +++ F L
Sbjct: 237 LPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQK 296
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L LDL N + +P L LS L LS
Sbjct: 297 LDELDLGSNKIENLPPLIFKDLKELSQLNLS 327
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/217 (27%), Positives = 93/217 (42%), Gaps = 2/217 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L +N I ++ +YAF LT L +S+N+I L FE + L + +N L R+
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTF-RDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
F G ++ + + + + L LD N + TF S+L +L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
+R N I + + L+ LDL N I+ + LKEL L+L+ N I+ +
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 336
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F L L+ L L ++ I L NLSH+Y
Sbjct: 337 NQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIY 373
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 75.8 bits (178), Expect = 4e-13
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL ++ + +T + + +N I L + F++ +++ L L NN + + AF G
Sbjct: 117 NLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSL 176
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I+ + F DL LE L +N L P TF L+SL +L L NN +
Sbjct: 177 TKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTR 236
Query: 180 IPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+P L + L +LDL N I + L L + N I +++ F L
Sbjct: 237 LPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQK 296
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L LDL N + +P L LS L LS
Sbjct: 297 LDELDLGSNKIENLPPLIFKDLKELSQLNLS 327
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/217 (27%), Positives = 93/217 (42%), Gaps = 2/217 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L +N I ++ +YAF LT L +S+N+I L FE + L + +N L R+
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTF-RDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
F G ++ + + + + L LD N + TF S+L +L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
+R N I + + L+ LDL N I+ + LKEL L+L+ N I+ +
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 336
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F L L+ L L ++ I L NLSH+Y
Sbjct: 337 NQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIY 373
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 75.8 bits (178), Expect = 4e-13
Identities = 42/132 (31%), Positives = 70/132 (53%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
Q TVLD+ +N+I ++ F+ + L L+NN ++++ ++AF G EI
Sbjct: 51 QTTVLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEI 110
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
+ QTF+ L +LE L +S ++L +PETF L L+ L L NN + IP+ + +
Sbjct: 111 HALDKQTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLD 170
Query: 190 HLEYLDLSENLI 201
L+ L L N +
Sbjct: 171 SLKRLRLDSNAL 182
Score = 71.3 bits (167), Expect = 8e-12
Identities = 48/163 (29%), Positives = 75/163 (46%), Gaps = 4/163 (2%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLD 75
CP RC+C + C + L+ +P Q+ + T+++L N I + AF L L
Sbjct: 24 CPSRCLCFKS--TVRCMHLMLDHIP-QVPQQTTVLDLRFNRIREIPGSAFKKLKNLNTLL 80
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
++ N I + FE + +L L N + LDK F G ++ + +
Sbjct: 81 LNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLVYSFHQLEMLQPE 140
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
TF DL LERL NN+L +F L SLK L L +N+++
Sbjct: 141 TFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSNALV 183
Score = 51.6 bits (118), Expect = 7e-06
Identities = 32/100 (32%), Positives = 52/100 (52%)
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
+L LR N I +IP + + +L L L+ N I+++SR+ L+ L +L L N I ++
Sbjct: 54 VLDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHAL 113
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
D+ F L SL HL S + + ++ L L L+L
Sbjct: 114 DKQTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFL 153
Score = 50.8 bits (116), Expect = 1e-05
Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 3/142 (2%)
Query: 242 LDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERI 301
LDL N + IP SA KL NL+ L L+ +
Sbjct: 55 LDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEI-HAL 113
Query: 302 DSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRL 360
D + F I+L+ + + + ++ + P F +L +++ NN L + A F +D L
Sbjct: 114 DKQTFKGLISLEHLVYSFH-QLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSL 172
Query: 361 QELEISGNPFACNCSLLWLWKL 382
+ L + N C+C L+WL +L
Sbjct: 173 KRLRLDSNALVCDCDLMWLGEL 194
Score = 49.6 bits (113), Expect = 3e-05
Identities = 37/123 (30%), Positives = 55/123 (44%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
LD NR+ F+ L +L L L NN I I + +L YL L +N I +
Sbjct: 55 LDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALD 114
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
+ L L+HL + + +E + F L L L L +N ++ IP + S L +L
Sbjct: 115 KQTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKR 174
Query: 266 LYL 268
L L
Sbjct: 175 LRL 177
Score = 46.4 bits (105), Expect = 3e-04
Identities = 34/119 (28%), Positives = 51/119 (42%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I I F+ L L L +NN + FE L +L L L N I + +
Sbjct: 62 IREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGL 121
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
I LE+L S + ++ + L L+ L L+NN + + F +L SL+ L L N
Sbjct: 122 ISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRLRLDSN 180
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/76 (32%), Positives = 35/76 (46%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL N I+++ LK L L LNNN I + + F L +L +L L N + +
Sbjct: 55 LDLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALD 114
Query: 254 TSALSKLSNLSHLYLS 269
L +L HL S
Sbjct: 115 KQTFKGLISLEHLVYS 130
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 75.8 bits (178), Expect = 4e-13
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 1/211 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL ++ + +T + + +N I L + F++ +++ L L NN + + AF G
Sbjct: 117 NLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSL 176
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I+ + F DL LE L +N L P TF L+SL +L L NN +
Sbjct: 177 TKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTR 236
Query: 180 IPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+P L + L +LDL N I + L L + N I +++ F L
Sbjct: 237 LPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQK 296
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L LDL N + +P L LS L LS
Sbjct: 297 LDELDLGSNKIENLPPLIFKDLKELSQLNLS 327
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/217 (27%), Positives = 93/217 (42%), Gaps = 2/217 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L +N I ++ +YAF LT L +S+N+I L FE + L + +N L R+
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTF-RDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
F G ++ + + + + L LD N + TF S+L +L
Sbjct: 217 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 276
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
+R N I + + L+ LDL N I+ + LKEL L+L+ N I+ +
Sbjct: 277 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 336
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F L L+ L L ++ I L NLSH+Y
Sbjct: 337 NQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIY 373
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/217 (29%), Positives = 110/217 (50%), Gaps = 8/217 (3%)
Query: 47 EATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK 106
+ T + +++N + +L L LTVLDI N++ L S E + ++ LN+S+N LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELEN-LQKLNVSHNKLK 141
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L ++ E++ I + F LS LE LD SNN L T P +F LSS
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCIS-EGFEQLSNLEDLDLSNNHLTTV-PASFSSLSS 198
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L L+L +N + +P A + + L++LD + NL++ + L ++ L+ L L N +
Sbjct: 199 LVRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLR 256
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + F S L+ L + +N + ++ L L+++
Sbjct: 257 FLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSI 291
Score = 72.9 bits (171), Expect = 3e-12
Identities = 68/224 (30%), Positives = 111/224 (49%), Gaps = 17/224 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+N++HN + L L L + +N++ + SE FE S + L+LSNN L +
Sbjct: 133 LNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
+F E+ ++ + R + L+ LD ++N L T PE + SL++L
Sbjct: 192 -SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPE-LAGMESLELL 248
Query: 171 SLRNNSIL---DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
LR N + + PS +L L+ L + EN I+ + L L + LDL +N ++S
Sbjct: 249 YLRRNKLRFLPEFPSCSL-----LKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKS 303
Query: 228 V-DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
V D++ L SL LDLS+N+++ +P S L L +L L L G
Sbjct: 304 VPDEIIL--LRSLERLDLSNNDISSLPYS-LGNL-HLKFLALEG 343
Score = 59.7 bits (138), Expect = 3e-08
Identities = 42/127 (33%), Positives = 73/127 (57%), Gaps = 5/127 (3%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L +L SNN+L + + L +L +L + +N + +PSA + + +L+ L++S N ++
Sbjct: 84 LTKLIISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLK 141
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ + L+ LK L L +N + + + GF L +L LDLS+N++T +P S S LS+
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCISE-GFEQLSNLEDLDLSNNHLTTVPAS-FSSLSS 198
Query: 263 LSHLYLS 269
L L LS
Sbjct: 199 LVRLNLS 205
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
+D S N+L E L L L LRNN + +P + ++ L+ ++LS N + +
Sbjct: 454 VDLSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRFKMLP 511
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L + L+ + ++NN + SVD + +L LDL +N++ IP L NL
Sbjct: 512 EV-LYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVNLRT 569
Query: 266 LYLSG 270
L L G
Sbjct: 570 LLLDG 574
Score = 41.9 bits (94), Expect = 0.006
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL--DKDAFVGXXXXXXXXXXXXEISN 131
+D+S+NK+ + E ++ L+L NNFL L + ++ V +
Sbjct: 454 VDLSFNKLSFISLELCVLQ-KLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPE 512
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ + F LE + SNN++ + +P+ + + +L L L+NN +L IP LG ++L
Sbjct: 513 VLYRIF----TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIP-PELGNCVNL 567
Query: 192 EYLDLSEN 199
L L N
Sbjct: 568 RTLLLDGN 575
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/217 (29%), Positives = 110/217 (50%), Gaps = 8/217 (3%)
Query: 47 EATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK 106
+ T + +++N + +L L LTVLDI N++ L S E + ++ LN+S+N LK
Sbjct: 62 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELEN-LQKLNVSHNKLK 120
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L ++ E++ I + F LS LE LD SNN L T P +F LSS
Sbjct: 121 ILPEE-ITNLRNLKCLYLQHNELTCIS-EGFEQLSNLEDLDLSNNHLTTV-PASFSSLSS 177
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L L+L +N + +P A + + L++LD + NL++ + L ++ L+ L L N +
Sbjct: 178 LVRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLR 235
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + F S L+ L + +N + ++ L L+++
Sbjct: 236 FLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSI 270
Score = 72.9 bits (171), Expect = 3e-12
Identities = 68/224 (30%), Positives = 111/224 (49%), Gaps = 17/224 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+N++HN + L L L + +N++ + SE FE S + L+LSNN L +
Sbjct: 112 LNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPA 170
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
+F E+ ++ + R + L+ LD ++N L T PE + SL++L
Sbjct: 171 -SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPE-LAGMESLELL 227
Query: 171 SLRNNSIL---DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
LR N + + PS +L L+ L + EN I+ + L L + LDL +N ++S
Sbjct: 228 YLRRNKLRFLPEFPSCSL-----LKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKS 282
Query: 228 V-DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
V D++ L SL LDLS+N+++ +P S L L +L L L G
Sbjct: 283 VPDEIIL--LRSLERLDLSNNDISSLPYS-LGNL-HLKFLALEG 322
Score = 59.7 bits (138), Expect = 3e-08
Identities = 42/127 (33%), Positives = 73/127 (57%), Gaps = 5/127 (3%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L +L SNN+L + + L +L +L + +N + +PSA + + +L+ L++S N ++
Sbjct: 63 LTKLIISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLK 120
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ + L+ LK L L +N + + + GF L +L LDLS+N++T +P S S LS+
Sbjct: 121 ILPEE-ITNLRNLKCLYLQHNELTCISE-GFEQLSNLEDLDLSNNHLTTVPAS-FSSLSS 177
Query: 263 LSHLYLS 269
L L LS
Sbjct: 178 LVRLNLS 184
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
+D S N+L E L L L LRNN + +P + ++ L+ ++LS N + +
Sbjct: 433 VDLSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRFKMLP 490
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L + L+ + ++NN + SVD + +L LDL +N++ IP L NL
Sbjct: 491 EV-LYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVNLRT 548
Query: 266 LYLSG 270
L L G
Sbjct: 549 LLLDG 553
Score = 41.9 bits (94), Expect = 0.006
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL--DKDAFVGXXXXXXXXXXXXEISN 131
+D+S+NK+ + E ++ L+L NNFL L + ++ V +
Sbjct: 433 VDLSFNKLSFISLELCVLQ-KLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPE 491
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ + F LE + SNN++ + +P+ + + +L L L+NN +L IP LG ++L
Sbjct: 492 VLYRIF----TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIP-PELGNCVNL 546
Query: 192 EYLDLSEN 199
L L N
Sbjct: 547 RTLLLDGN 554
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/217 (29%), Positives = 110/217 (50%), Gaps = 8/217 (3%)
Query: 47 EATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK 106
+ T + +++N + +L L LTVLDI N++ L S E + ++ LN+S+N LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELEN-LQKLNVSHNKLK 141
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L ++ E++ I + F LS LE LD SNN L T P +F LSS
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCIS-EGFEQLSNLEDLDLSNNHLTTV-PASFSSLSS 198
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L L+L +N + +P A + + L++LD + NL++ + L ++ L+ L L N +
Sbjct: 199 LVRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLR 256
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + F S L+ L + +N + ++ L L+++
Sbjct: 257 FLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSI 291
Score = 72.9 bits (171), Expect = 3e-12
Identities = 68/224 (30%), Positives = 111/224 (49%), Gaps = 17/224 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+N++HN + L L L + +N++ + SE FE S + L+LSNN L +
Sbjct: 133 LNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
+F E+ ++ + R + L+ LD ++N L T PE + SL++L
Sbjct: 192 -SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPE-LAGMESLELL 248
Query: 171 SLRNNSIL---DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
LR N + + PS +L L+ L + EN I+ + L L + LDL +N ++S
Sbjct: 249 YLRRNKLRFLPEFPSCSL-----LKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKS 303
Query: 228 V-DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
V D++ L SL LDLS+N+++ +P S L L +L L L G
Sbjct: 304 VPDEIIL--LRSLERLDLSNNDISSLPYS-LGNL-HLKFLALEG 343
Score = 59.7 bits (138), Expect = 3e-08
Identities = 42/127 (33%), Positives = 73/127 (57%), Gaps = 5/127 (3%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L +L SNN+L + + L +L +L + +N + +PSA + + +L+ L++S N ++
Sbjct: 84 LTKLIISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLK 141
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ + L+ LK L L +N + + + GF L +L LDLS+N++T +P S S LS+
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCISE-GFEQLSNLEDLDLSNNHLTTVPAS-FSSLSS 198
Query: 263 LSHLYLS 269
L L LS
Sbjct: 199 LVRLNLS 205
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
+D S N+L E L L L LRNN + +P + ++ L+ ++LS N + +
Sbjct: 454 VDLSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRFKMLP 511
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L + L+ + ++NN + SVD + +L LDL +N++ IP L NL
Sbjct: 512 EV-LYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVNLRT 569
Query: 266 LYLSG 270
L L G
Sbjct: 570 LLLDG 574
Score = 41.9 bits (94), Expect = 0.006
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL--DKDAFVGXXXXXXXXXXXXEISN 131
+D+S+NK+ + E ++ L+L NNFL L + ++ V +
Sbjct: 454 VDLSFNKLSFISLELCVLQ-KLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPE 512
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ + F LE + SNN++ + +P+ + + +L L L+NN +L IP LG ++L
Sbjct: 513 VLYRIF----TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIP-PELGNCVNL 567
Query: 192 EYLDLSEN 199
L L N
Sbjct: 568 RTLLLDGN 575
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 75.4 bits (177), Expect = 5e-13
Identities = 63/217 (29%), Positives = 110/217 (50%), Gaps = 8/217 (3%)
Query: 47 EATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK 106
+ T + +++N + +L L LTVLDI N++ L S E + ++ LN+S+N LK
Sbjct: 83 DLTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELEN-LQKLNVSHNKLK 141
Query: 107 RLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSS 166
L ++ E++ I + F LS LE LD SNN L T P +F LSS
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCIS-EGFEQLSNLEDLDLSNNHLTTV-PASFSSLSS 198
Query: 167 LKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE 226
L L+L +N + +P A + + L++LD + NL++ + L ++ L+ L L N +
Sbjct: 199 LVRLNLSSNELKSLP-AEINRMKRLKHLDCNSNLLETIPPE-LAGMESLELLYLRRNKLR 256
Query: 227 SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ + F S L+ L + +N + ++ L L+++
Sbjct: 257 FLPE--FPSCSLLKELHVGENQIEMLEAEHLKHLNSI 291
Score = 72.9 bits (171), Expect = 3e-12
Identities = 68/224 (30%), Positives = 111/224 (49%), Gaps = 17/224 (7%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+N++HN + L L L + +N++ + SE FE S + L+LSNN L +
Sbjct: 133 LNVSHNKLKILPEEITNLRNLKCLYLQHNELTCI-SEGFEQLSNLEDLDLSNNHLTTVPA 191
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
+F E+ ++ + R + L+ LD ++N L T PE + SL++L
Sbjct: 192 -SFSSLSSLVRLNLSSNELKSLPAEINR-MKRLKHLDCNSNLLETIPPE-LAGMESLELL 248
Query: 171 SLRNNSIL---DIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
LR N + + PS +L L+ L + EN I+ + L L + LDL +N ++S
Sbjct: 249 YLRRNKLRFLPEFPSCSL-----LKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKS 303
Query: 228 V-DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
V D++ L SL LDLS+N+++ +P S L L +L L L G
Sbjct: 304 VPDEIIL--LRSLERLDLSNNDISSLPYS-LGNL-HLKFLALEG 343
Score = 59.7 bits (138), Expect = 3e-08
Identities = 42/127 (33%), Positives = 73/127 (57%), Gaps = 5/127 (3%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L +L SNN+L + + L +L +L + +N + +PSA + + +L+ L++S N ++
Sbjct: 84 LTKLIISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLK 141
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ + L+ LK L L +N + + + GF L +L LDLS+N++T +P S S LS+
Sbjct: 142 ILPEE-ITNLRNLKCLYLQHNELTCISE-GFEQLSNLEDLDLSNNHLTTVPAS-FSSLSS 198
Query: 263 LSHLYLS 269
L L LS
Sbjct: 199 LVRLNLS 205
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/125 (29%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
+D S N+L E L L L LRNN + +P + ++ L+ ++LS N + +
Sbjct: 454 VDLSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPE-EMESLVRLQTINLSFNRFKMLP 511
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
L + L+ + ++NN + SVD + +L LDL +N++ IP L NL
Sbjct: 512 EV-LYRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPE-LGNCVNLRT 569
Query: 266 LYLSG 270
L L G
Sbjct: 570 LLLDG 574
Score = 41.9 bits (94), Expect = 0.006
Identities = 34/128 (26%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL--DKDAFVGXXXXXXXXXXXXEISN 131
+D+S+NK+ + E ++ L+L NNFL L + ++ V +
Sbjct: 454 VDLSFNKLSFISLELCVLQ-KLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPE 512
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ + F LE + SNN++ + +P+ + + +L L L+NN +L IP LG ++L
Sbjct: 513 VLYRIF----TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIP-PELGNCVNL 567
Query: 192 EYLDLSEN 199
L L N
Sbjct: 568 RTLLLDGN 575
>U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein.
Length = 359
Score = 74.9 bits (176), Expect = 7e-13
Identities = 69/279 (24%), Positives = 115/279 (41%), Gaps = 26/279 (9%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
LNL N L ++F +I + FR L L L S+N +
Sbjct: 56 LNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVR 115
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L+ L L L +N + ++P L +++L L L+ N I+++ K+L+
Sbjct: 116 AGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRW 175
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXX 277
L L+ N + S+ + +L + N ++ P++ALSKL + L LS
Sbjct: 176 LYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS-------- 227
Query: 278 XXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKL 337
R ++DN NL+K +D F G L
Sbjct: 228 ------HNPLKSIPDNAFQSFGRYLETLWLDNTNLEK--FSDGA---------FLGVTTL 270
Query: 338 TNIYMKNNALETLEASHFPIDRLQELEISGNPFACNCSL 376
+++++NN L L S+FP D L+ L ++ NP+ C C L
Sbjct: 271 KHVHLENNRLNQL-PSNFPFDSLETLALTNNPWKCTCQL 308
Score = 65.7 bits (153), Expect = 4e-10
Identities = 55/258 (21%), Positives = 106/258 (41%), Gaps = 3/258 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQL 71
A CP C C L+ C L+ +P +++ + L+NL N L +F L
Sbjct: 19 ALAACPQNCHCHSDLQHVICDKVGLQKIP-KVSEKTKLLNLQRNNFPVLAANSFRAMPNL 77
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
L + + +I ++ + F ++ +L LS+N ++ + AF +++
Sbjct: 78 VSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVVRAGAFDDLTELTYLYLDHNKVTE 137
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ L L L +NN++ F+ L+ L L N++ + L V +L
Sbjct: 138 LPRGLLSPLVNLFILQLNNNKIRELRAGPFQGAKDLRWLYLSENALSSLQPGALDDVENL 197
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS-LRHLDLSDNNMT 250
+ N + L L+ ++ L L++N ++S+ F S L L L + N+
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLE 257
Query: 251 LIPTSALSKLSNLSHLYL 268
A ++ L H++L
Sbjct: 258 KFSDGAFLGVTTLKHVHL 275
>BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein.
Length = 384
Score = 74.9 bits (176), Expect = 7e-13
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C R C++ L VP + + +++L +N I + F T L L
Sbjct: 78 MCPFGCQCYS--RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 135
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
++ NK+ + + F + ++R L LS+N L + + ++ I
Sbjct: 136 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQK 192
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF+ ++AL L+ S N L EP FE ++ I + + +P G L
Sbjct: 193 DTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHI-RIAEAKLTSVPK---GLPPTLL 248
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I V KEL+ L L NN I ++ ++P +R + L +N + I
Sbjct: 249 ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKI 308
Query: 253 PTSALSKLSNLSHLYL 268
P S L +L L ++L
Sbjct: 309 P-SGLPELKYLQIIFL 323
Score = 37.9 bits (84), Expect = 0.094
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+PF + + LDL NN I+ + + F L SL L L++N +T I A L LYL
Sbjct: 104 IPF--DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYL 161
Query: 269 S 269
S
Sbjct: 162 S 162
>AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein.
Length = 379
Score = 74.9 bits (176), Expect = 7e-13
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C R C++ L VP + + +++L +N I + F T L L
Sbjct: 73 MCPFGCQCYS--RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 130
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
++ NK+ + + F + ++R L LS+N L + + ++ I
Sbjct: 131 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQK 187
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF+ ++AL L+ S N L EP FE ++ I + + +P G L
Sbjct: 188 DTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHI-RIAEAKLTSVPK---GLPPTLL 243
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I V KEL+ L L NN I ++ ++P +R + L +N + I
Sbjct: 244 ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKI 303
Query: 253 PTSALSKLSNLSHLYL 268
P S L +L L ++L
Sbjct: 304 P-SGLPELKYLQIIFL 318
Score = 37.9 bits (84), Expect = 0.094
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+PF + + LDL NN I+ + + F L SL L L++N +T I A L LYL
Sbjct: 99 IPF--DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYL 156
Query: 269 S 269
S
Sbjct: 157 S 157
>AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3
protein.
Length = 420
Score = 74.9 bits (176), Expect = 7e-13
Identities = 55/174 (31%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR-LV 154
+ L L NN ++ L F +S I+ TFR L ALE LD +NR L
Sbjct: 63 QRLFLQNNLIRTLRPSTF--GSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
+ EP+TF+ L L+ L L + +P ++ L+YL L EN + + L
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L HL L+ N + + + F L SL L L N + + +A LS L+ LYL
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYL 234
Score = 73.3 bits (172), Expect = 2e-12
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 2/232 (0%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP+ C C + SC N VP+ L P + L +N I L + L L +
Sbjct: 31 CPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLI-RTLRPSTFGSNLLTLWL 89
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNN-FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
N + + F + L+L +N L+ L+ D F G ++S++
Sbjct: 90 FSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR L +L+ L N L+ + + F L++L L L N + + + L+ L
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L N +Q V R L L L L NN + S+ LPSL L L+ N
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 53.2 bits (122), Expect = 2e-06
Identities = 40/128 (31%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL-IQ 202
+RL NN + T P TF S+L L L +N++ I + LE LDL +N ++
Sbjct: 63 QRLFLQNNLIRTLRPSTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ L+ L+ L L + S+ F L SL++L L +N++ + + L+N
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 263 LSHLYLSG 270
LSHL+L G
Sbjct: 181 LSHLFLHG 188
Score = 51.2 bits (117), Expect = 9e-06
Identities = 52/219 (23%), Positives = 92/219 (42%), Gaps = 8/219 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI- 224
S + L L+NN I + + G +L L L N + + L+ L+ LDL +N
Sbjct: 61 STQRLFLQNNLIRTLRPSTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRH 118
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
+ S++ F L L+ L L ++ +P + L +L +LYL
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQ-ENSLLHLQDDLFAD 177
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ F +L ++ ++ N +++ V F G +LT +Y+ N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGN-RLQGVHRAAFRGLSRLTILYLFN 236
Query: 345 NALETLEASHFP-IDRLQELEISGNPFACNCSL--LWLW 380
N+L +L + L+ L ++ NP+AC+C LW W
Sbjct: 237 NSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW 275
>AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament
associated protein 1 protein.
Length = 381
Score = 74.9 bits (176), Expect = 7e-13
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C R C++ L VP + + +++L +N I + F T L L
Sbjct: 75 MCPFGCQCYS--RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 132
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
++ NK+ + + F + ++R L LS+N L + + ++ I
Sbjct: 133 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQK 189
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF+ ++AL L+ S N L EP FE ++ I + + +P G L
Sbjct: 190 DTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHI-RIAEAKLTSVPK---GLPPTLL 245
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I V KEL+ L L NN I ++ ++P +R + L +N + I
Sbjct: 246 ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKI 305
Query: 253 PTSALSKLSNLSHLYL 268
P S L +L L ++L
Sbjct: 306 P-SGLPELKYLQIIFL 320
Score = 37.9 bits (84), Expect = 0.094
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+PF + + LDL NN I+ + + F L SL L L++N +T I A L LYL
Sbjct: 101 IPF--DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYL 158
Query: 269 S 269
S
Sbjct: 159 S 159
>AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1)
protein.
Length = 380
Score = 74.9 bits (176), Expect = 7e-13
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C R C++ L VP + + +++L +N I + F T L L
Sbjct: 74 MCPFGCQCYS--RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
++ NK+ + + F + ++R L LS+N L + + ++ I
Sbjct: 132 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQK 188
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF+ ++AL L+ S N L EP FE ++ I + + +P G L
Sbjct: 189 DTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHI-RIAEAKLTSVPK---GLPPTLL 244
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I V KEL+ L L NN I ++ ++P +R + L +N + I
Sbjct: 245 ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKI 304
Query: 253 PTSALSKLSNLSHLYL 268
P S L +L L ++L
Sbjct: 305 P-SGLPELKYLQIIFL 319
Score = 37.9 bits (84), Expect = 0.094
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+PF + + LDL NN I+ + + F L SL L L++N +T I A L LYL
Sbjct: 100 IPF--DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYL 157
Query: 269 S 269
S
Sbjct: 158 S 158
>AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein.
Length = 379
Score = 74.9 bits (176), Expect = 7e-13
Identities = 66/256 (25%), Positives = 110/256 (42%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C R C++ L VP + + +++L +N I + F T L L
Sbjct: 73 MCPFGCQCYS--RVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 130
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
++ NK+ + + F + ++R L LS+N L + + ++ I
Sbjct: 131 ILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNL---PKSLAELRIHENKVKKIQK 187
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF+ ++AL L+ S N L EP FE ++ I + + +P G L
Sbjct: 188 DTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHI-RIAEAKLTSVPK---GLPPTLL 243
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N I V KEL+ L L NN I ++ ++P +R + L +N + I
Sbjct: 244 ELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENNKLKKI 303
Query: 253 PTSALSKLSNLSHLYL 268
P S L +L L ++L
Sbjct: 304 P-SGLPELKYLQIIFL 318
Score = 37.9 bits (84), Expect = 0.094
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+PF + + LDL NN I+ + + F L SL L L++N +T I A L LYL
Sbjct: 99 IPF--DTRMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYL 156
Query: 269 S 269
S
Sbjct: 157 S 157
>AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 variant
protein.
Length = 627
Score = 74.9 bits (176), Expect = 7e-13
Identities = 59/217 (27%), Positives = 93/217 (42%), Gaps = 2/217 (0%)
Query: 53 LTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
L +N I ++ +YAF LT L +S+N+I L FE + L + +N L R+
Sbjct: 27 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 86
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTF-RDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
F G ++ + + + + L LD N + TF S+L +L
Sbjct: 87 TFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVL 146
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQ 230
+R N I + + L+ LDL N I+ + LKEL L+L+ N I+ +
Sbjct: 147 VMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQA 206
Query: 231 LGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
F L L+ L L ++ I L NLSH+Y
Sbjct: 207 NQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIY 243
Score = 39.5 bits (88), Expect = 0.031
Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 1/120 (0%)
Query: 150 NNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGL 209
NN++ + F L+SL L L +N I + + LE+L + +N + ++S
Sbjct: 29 NNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTF 88
Query: 210 PFLKELKHLDLNNNIIESV-DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L L L L NN++ + D+ +P L LDL N++ + SNL+ L +
Sbjct: 89 YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVM 148
>BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 74.5 bits (175), Expect = 9e-13
Identities = 55/174 (31%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR-LV 154
+ L L NN ++ L F +S I+ TFR L ALE LD +NR L
Sbjct: 63 QRLFLQNNLIRTLRPGTF--GSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
+ EP+TF+ L L+ L L + +P ++ L+YL L EN + + L
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L HL L+ N + + + F L SL L L N + + +A LS L+ LYL
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYL 234
Score = 72.9 bits (171), Expect = 3e-12
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 2/232 (0%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP+ C C + SC N VP+ L P + L +N I L + L L +
Sbjct: 31 CPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLI-RTLRPGTFGSNLLTLWL 89
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNN-FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
N + + F + L+L +N L+ L+ D F G ++S++
Sbjct: 90 FSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR L +L+ L N L+ + + F L++L L L N + + + L+ L
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L N +Q V R L L L L NN + S+ LPSL L L+ N
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/128 (31%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL-IQ 202
+RL NN + T P TF S+L L L +N++ I + LE LDL +N ++
Sbjct: 63 QRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ L+ L+ L L + S+ F L SL++L L +N++ + + L+N
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 263 LSHLYLSG 270
LSHL+L G
Sbjct: 181 LSHLFLHG 188
Score = 50.8 bits (116), Expect = 1e-05
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 8/219 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI- 224
S + L L+NN I + G +L L L N + + L+ L+ LDL +N
Sbjct: 61 STQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRH 118
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
+ S++ F L L+ L L ++ +P + L +L +LYL
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQ-ENSLLHLQDDLFAD 177
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ F +L ++ ++ N +++ V F G +LT +Y+ N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGN-RLQGVHRAAFRGLSRLTILYLFN 236
Query: 345 NALETLEASHFP-IDRLQELEISGNPFACNCSL--LWLW 380
N+L +L + L+ L ++ NP+AC+C LW W
Sbjct: 237 NSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW 275
>BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-like
2 protein.
Length = 420
Score = 74.5 bits (175), Expect = 9e-13
Identities = 55/174 (31%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR-LV 154
+ L L NN ++ L F +S I+ TFR L ALE LD +NR L
Sbjct: 63 QRLFLQNNLIRTLRPGTF--GSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
+ EP+TF+ L L+ L L + +P ++ L+YL L EN + + L
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L HL L+ N + + + F L SL L L N + + +A LS L+ LYL
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYL 234
Score = 72.9 bits (171), Expect = 3e-12
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 2/232 (0%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP+ C C + SC N VP+ L P + L +N I L + L L +
Sbjct: 31 CPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLI-RTLRPGTFGSNLLTLWL 89
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNN-FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
N + + F + L+L +N L+ L+ D F G ++S++
Sbjct: 90 FSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR L +L+ L N L+ + + F L++L L L N + + + L+ L
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L N +Q V R L L L L NN + S+ LPSL L L+ N
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/128 (31%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL-IQ 202
+RL NN + T P TF S+L L L +N++ I + LE LDL +N ++
Sbjct: 63 QRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ L+ L+ L L + S+ F L SL++L L +N++ + + L+N
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 263 LSHLYLSG 270
LSHL+L G
Sbjct: 181 LSHLFLHG 188
Score = 50.8 bits (116), Expect = 1e-05
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 8/219 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI- 224
S + L L+NN I + G +L L L N + + L+ L+ LDL +N
Sbjct: 61 STQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRH 118
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
+ S++ F L L+ L L ++ +P + L +L +LYL
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQ-ENSLLHLQDDLFAD 177
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ F +L ++ ++ N +++ V F G +LT +Y+ N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGN-RLQGVHRAAFRGLSRLTILYLFN 236
Query: 345 NALETLEASHFP-IDRLQELEISGNPFACNCSL--LWLW 380
N+L +L + L+ L ++ NP+AC+C LW W
Sbjct: 237 NSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW 275
>AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolog-1
protein.
Length = 420
Score = 74.5 bits (175), Expect = 9e-13
Identities = 55/174 (31%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR-LV 154
+ L L NN ++ L F +S I+ TFR L ALE LD +NR L
Sbjct: 63 QRLFLQNNLIRTLRPGTF--GSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
+ EP+TF+ L L+ L L + +P ++ L+YL L EN + + L
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L HL L+ N + + + F L SL L L N + + +A LS L+ LYL
Sbjct: 181 LSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFRGLSRLTILYL 234
Score = 72.9 bits (171), Expect = 3e-12
Identities = 62/232 (26%), Positives = 95/232 (40%), Gaps = 2/232 (0%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP+ C C + SC N VP+ L P + L +N I L + L L +
Sbjct: 31 CPMLCTCYSSPPTVSCQANNFSSVPLSLPPSTQRLFLQNNLI-RTLRPGTFGSNLLTLWL 89
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNN-FLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
N + + F + L+L +N L+ L+ D F G ++S++
Sbjct: 90 FSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 149
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR L +L+ L N L+ + + F L++L L L N + + + L+ L
Sbjct: 150 IFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLL 209
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L N +Q V R L L L L NN + S+ LPSL L L+ N
Sbjct: 210 LHGNRLQGVHRAAFRGLSRLTILYLFNNSLASLPGEALADLPSLEFLRLNAN 261
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/128 (31%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL-IQ 202
+RL NN + T P TF S+L L L +N++ I + LE LDL +N ++
Sbjct: 63 QRLFLQNNLIRTLRPGTFG--SNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLR 120
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
+ L+ L+ L L + S+ F L SL++L L +N++ + + L+N
Sbjct: 121 SLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLAN 180
Query: 263 LSHLYLSG 270
LSHL+L G
Sbjct: 181 LSHLFLHG 188
Score = 50.8 bits (116), Expect = 1e-05
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 8/219 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI- 224
S + L L+NN I + G +L L L N + + L+ L+ LDL +N
Sbjct: 61 STQRLFLQNNLIRTLRPGTFGS--NLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNRH 118
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXX 284
+ S++ F L L+ L L ++ +P + L +L +LYL
Sbjct: 119 LRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQ-ENSLLHLQDDLFAD 177
Query: 285 XXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKN 344
+ F +L ++ ++ N +++ V F G +LT +Y+ N
Sbjct: 178 LANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGN-RLQGVHRAAFRGLSRLTILYLFN 236
Query: 345 NALETLEASHFP-IDRLQELEISGNPFACNCSL--LWLW 380
N+L +L + L+ L ++ NP+AC+C LW W
Sbjct: 237 NSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAW 275
>X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin
glycoprotein protein.
Length = 440
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
+ LF + +CP++C+C + R C+ NL +P L +NL++N +
Sbjct: 10 LCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTD 69
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
L YT L LDIS N++ L + S + +++ +NN +K LDK
Sbjct: 70 LHNQLTQYTNLRTLDISNNRLESLPAHLPRS---LWNMSAANNNIKLLDKSDTAYQWNLK 126
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
+ + V L +LE L+ S+N+L T T P S L I+ L NNS+ I
Sbjct: 127 YLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTV--PTNMP-SKLHIVDLSNNSLTQI 182
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L + +L +L L N + L +L+ + L NN
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/127 (35%), Positives = 75/127 (59%), Gaps = 9/127 (7%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L LD SNNRL + P SL +S NN+I + ++ + +L+YLD+S+N+++
Sbjct: 80 LRTLDISNNRLESLPAHL--P-RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL-DLSDNNMTLIPTSALSKLS 261
+V L+ L+ L+L++N + +V ++PS H+ DLS+N++T I L L+
Sbjct: 137 KVVLIKNT-LRSLEVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLT 191
Query: 262 NLSHLYL 268
NL+HLYL
Sbjct: 192 NLTHLYL 198
Score = 31.9 bits (69), Expect = 6.2
Identities = 22/102 (21%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++++ N ++ ++ N L VL++S NK+ + + S++ ++LSNN L ++
Sbjct: 128 LDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTN---MPSKLHIVDLSNNSLTQILP 184
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ + + I Q+F L L+ + NNR
Sbjct: 185 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
>X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 433
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
+ LF + +CP++C+C + R C+ NL +P L +NL++N +
Sbjct: 3 LCLFILLFLTPXILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTD 62
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
L YT L LDIS N++ L + S + +++ +NN +K LDK
Sbjct: 63 LHNQLTQYTNLRTLDISNNRLESLPAHLPRS---LWNMSAANNNIKLLDKSDTAYQWNLK 119
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
+ + V L +LE L+ S+N+L T T P S L I+ L NNS+ I
Sbjct: 120 YLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTV--PTNMP-SKLHIVDLSNNSLTQI 175
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L + +L +L L N + L +L+ + L NN
Sbjct: 176 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 218
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/127 (35%), Positives = 75/127 (59%), Gaps = 9/127 (7%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L LD SNNRL + P SL +S NN+I + ++ + +L+YLD+S+N+++
Sbjct: 73 LRTLDISNNRLESLPAHL--P-RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 129
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL-DLSDNNMTLIPTSALSKLS 261
+V L+ L+ L+L++N + +V ++PS H+ DLS+N++T I L L+
Sbjct: 130 KVVLIKNT-LRSLEVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLT 184
Query: 262 NLSHLYL 268
NL+HLYL
Sbjct: 185 NLTHLYL 191
Score = 31.9 bits (69), Expect = 6.2
Identities = 22/102 (21%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++++ N ++ ++ N L VL++S NK+ + + S++ ++LSNN L ++
Sbjct: 121 LDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTN---MPSKLHIVDLSNNSLTQILP 177
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ + + I Q+F L L+ + NNR
Sbjct: 178 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 219
>M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 440
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
+ LF + +CP++C+C + R C+ NL +P L +NL++N +
Sbjct: 10 LCLFILLFLTPXILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTD 69
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
L YT L LDIS N++ L + S + +++ +NN +K LDK
Sbjct: 70 LHNQLTQYTNLRTLDISNNRLESLPAHLPRS---LWNMSAANNNIKLLDKSDTAYQWNLK 126
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
+ + V L +LE L+ S+N+L T T P S L I+ L NNS+ I
Sbjct: 127 YLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTV--PTNMP-SKLHIVDLSNNSLTQI 182
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L + +L +L L N + L +L+ + L NN
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/127 (35%), Positives = 75/127 (59%), Gaps = 9/127 (7%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L LD SNNRL + P SL +S NN+I + ++ + +L+YLD+S+N+++
Sbjct: 80 LRTLDISNNRLESLPAHL--P-RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL-DLSDNNMTLIPTSALSKLS 261
+V L+ L+ L+L++N + +V ++PS H+ DLS+N++T I L L+
Sbjct: 137 KVVLIKNT-LRSLEVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLT 191
Query: 262 NLSHLYL 268
NL+HLYL
Sbjct: 192 NLTHLYL 198
Score = 31.9 bits (69), Expect = 6.2
Identities = 22/102 (21%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++++ N ++ ++ N L VL++S NK+ + + S++ ++LSNN L ++
Sbjct: 128 LDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTN---MPSKLHIVDLSNNSLTQILP 184
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ + + I Q+F L L+ + NNR
Sbjct: 185 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
>J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA
encoding bone small proteoglycan I (biglycan), complete
cds. ).
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPK 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPK 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein protein.
Length = 440
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
+ LF + +CP++C+C + R C+ NL +P L +NL++N +
Sbjct: 10 LCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTD 69
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
L YT L LDIS N++ L + S + +++ +NN +K LDK
Sbjct: 70 LHNQLTQYTNLRTLDISNNRLESLPAHLPRS---LWNMSAANNNIKLLDKSDTAYQWNLK 126
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
+ + V L +LE L+ S+N+L T T P S L I+ L NNS+ I
Sbjct: 127 YLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTV--PTNMP-SKLHIVDLSNNSLTQI 182
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L + +L +L L N + L +L+ + L NN
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/127 (35%), Positives = 75/127 (59%), Gaps = 9/127 (7%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L LD SNNRL + P SL +S NN+I + ++ + +L+YLD+S+N+++
Sbjct: 80 LRTLDISNNRLESLPAHL--P-RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL-DLSDNNMTLIPTSALSKLS 261
+V L+ L+ L+L++N + +V ++PS H+ DLS+N++T I L L+
Sbjct: 137 KVVLIKNT-LRSLEVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLT 191
Query: 262 NLSHLYL 268
NL+HLYL
Sbjct: 192 NLTHLYL 198
Score = 31.9 bits (69), Expect = 6.2
Identities = 22/102 (21%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++++ N ++ ++ N L VL++S NK+ + + S++ ++LSNN L ++
Sbjct: 128 LDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTN---MPSKLHIVDLSNNSLTQILP 184
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ + + I Q+F L L+ + NNR
Sbjct: 185 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
>BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPK 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPK 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPK 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein variant protein.
Length = 440
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 98/223 (43%), Gaps = 7/223 (3%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
+ LF + +CP++C+C + R C+ NL +P L +NL++N +
Sbjct: 10 LCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTD 69
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
L YT L LDIS N++ L + S + +++ +NN +K LDK
Sbjct: 70 LHNQLTQYTNLRTLDISNNRLESLPAHLPRS---LWNMSAANNNIKLLDKSDTAYQWNLK 126
Query: 121 XXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI 180
+ + V L +LE L+ S+N+L T T P S L I+ L NNS+ I
Sbjct: 127 YLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTV--PTNMP-SKLHIVDLSNNSLTQI 182
Query: 181 PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L + +L +L L N + L +L+ + L NN
Sbjct: 183 LPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/127 (35%), Positives = 75/127 (59%), Gaps = 9/127 (7%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQ 202
L LD SNNRL + P SL +S NN+I + ++ + +L+YLD+S+N+++
Sbjct: 80 LRTLDISNNRLESLPAHL--P-RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 203 QVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHL-DLSDNNMTLIPTSALSKLS 261
+V L+ L+ L+L++N + +V ++PS H+ DLS+N++T I L L+
Sbjct: 137 KVVLIKNT-LRSLEVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLT 191
Query: 262 NLSHLYL 268
NL+HLYL
Sbjct: 192 NLTHLYL 198
Score = 31.9 bits (69), Expect = 6.2
Identities = 22/102 (21%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++++ N ++ ++ N L VL++S NK+ + + S++ ++LSNN L ++
Sbjct: 128 LDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTN---MPSKLHIVDLSNNSLTQILP 184
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ + + I Q+F L L+ + NNR
Sbjct: 185 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226
>AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 73.7 bits (173), Expect = 2e-12
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 13/256 (5%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVL 74
+CP C C LR C++ L+ VP +++P+ TL++L +N I L F L L
Sbjct: 62 MCPFGCHCH--LRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ NKI + + F +++ L +S N L + + I +
Sbjct: 120 VLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNL---PSSLVELRIHDNRIRKVPE 176
Query: 135 QTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
F L + ++ N L FEP F+ L L L + + IP L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK---DLPETLN 232
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
L L N IQ + L +L L L +N I ++ LP+LR L L +N + +
Sbjct: 233 ELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARV 292
Query: 253 PTSALSKLSNLSHLYL 268
P S L L L +YL
Sbjct: 293 P-SGLPDLKLLQVVYL 307
Score = 32.7 bits (71), Expect = 3.6
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
HL + S+ ++ V + P + LDL NN I + + F L L L L +N +
Sbjct: 70 HLRVVQCSDLGLKSVPKEISP---DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKI 126
Query: 250 TLIPTSALSKLSNLSHLYLS 269
+ I A S L L LY+S
Sbjct: 127 SKIHEKAFSPLRKLQKLYIS 146
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 73.3 bits (172), Expect = 2e-12
Identities = 71/303 (23%), Positives = 123/303 (40%), Gaps = 18/303 (5%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ + +F L L+ LD S N++ + F+PL++L L L N + +I + +
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L +N I+ + L L L L +N + ++ L LP L LDLS N+
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNS 180
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ + L +N+ L L+G ER+
Sbjct: 181 LLALEPGILDT-ANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPP-VIRG 237
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPI-DRLQELEISG 367
L ++ + N ++ ++ P G L + + N +L+ L + RL+ L +
Sbjct: 238 LRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAAR 297
Query: 368 NPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESE 427
NPF C C L W ++S T E+ +C P + G L +++ ++
Sbjct: 298 NPFNCVCPLSWFGPWVRESHVTLASP-----------EETRCHFPPKNAGRLLLELDYAD 346
Query: 428 FGC 430
FGC
Sbjct: 347 FGC 349
Score = 65.7 bits (153), Expect = 4e-10
Identities = 71/255 (27%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C VP + P+ + + N I L +F L +LD
Sbjct: 24 CPSGCQCSQP-QTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLD 82
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I L S F+ + + +L+L+ N L EI+N +
Sbjct: 83 LSQNQIASLPSGVFQPLANLSNLDLTANRLH---------------------EITN---E 118
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
TFR L LERL NR+ +P F+ L L L L++N + +P L L LD
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP---RLLLLD 175
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
LS N + + G+ ++ L L ++ +D+ F L +L LD+SDN + +P
Sbjct: 176 LSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-P 233
Query: 256 ALSKLSNLSHLYLSG 270
+ L L+ L L+G
Sbjct: 234 VIRGLRGLTRLRLAG 248
Score = 37.5 bits (83), Expect = 0.12
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 3/131 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L +LD+S+N +L L + + L L+ L++LD+ F ++
Sbjct: 170 RLLLLDLSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
Query: 130 SNIHVQTFRDLSALERLDFSNN-RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ R L L RL + N R+ PE L++L+ L + N S+ +P G
Sbjct: 229 ERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLF 287
Query: 189 IHLEYLDLSEN 199
L L + N
Sbjct: 288 PRLRLLAAARN 298
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 73.3 bits (172), Expect = 2e-12
Identities = 71/303 (23%), Positives = 123/303 (40%), Gaps = 18/303 (5%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ + +F L L+ LD S N++ + F+PL++L L L N + +I + +
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L +N I+ + L L L L +N + ++ L LP L LDLS N+
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNS 180
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ + L +N+ L L+G ER+
Sbjct: 181 LLALEPGILDT-ANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPP-VIRG 237
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPI-DRLQELEISG 367
L ++ + N ++ ++ P G L + + N +L+ L + RL+ L +
Sbjct: 238 LRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAAR 297
Query: 368 NPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESE 427
NPF C C L W ++S T E+ +C P + G L +++ ++
Sbjct: 298 NPFNCVCPLSWFGPWVRESHVTLASP-----------EETRCHFPPKNAGRLLLELDYAD 346
Query: 428 FGC 430
FGC
Sbjct: 347 FGC 349
Score = 65.7 bits (153), Expect = 4e-10
Identities = 71/255 (27%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C VP + P+ + + N I L +F L +LD
Sbjct: 24 CPSGCQCSQP-QTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLD 82
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I L S F+ + + +L+L+ N L EI+N +
Sbjct: 83 LSQNQIASLPSGVFQPLANLSNLDLTANRLH---------------------EITN---E 118
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
TFR L LERL NR+ +P F+ L L L L++N + +P L L LD
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP---RLLLLD 175
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
LS N + + G+ ++ L L ++ +D+ F L +L LD+SDN + +P
Sbjct: 176 LSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-P 233
Query: 256 ALSKLSNLSHLYLSG 270
+ L L+ L L+G
Sbjct: 234 VIRGLRGLTRLRLAG 248
Score = 37.5 bits (83), Expect = 0.12
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 3/131 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L +LD+S+N +L L + + L L+ L++LD+ F ++
Sbjct: 170 RLLLLDLSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
Query: 130 SNIHVQTFRDLSALERLDFSNN-RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ R L L RL + N R+ PE L++L+ L + N S+ +P G
Sbjct: 229 ERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLF 287
Query: 189 IHLEYLDLSEN 199
L L + N
Sbjct: 288 PRLRLLAAARN 298
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 73.3 bits (172), Expect = 2e-12
Identities = 71/303 (23%), Positives = 123/303 (40%), Gaps = 18/303 (5%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ + +F L L+ LD S N++ + F+PL++L L L N + +I + +
Sbjct: 64 ITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL 123
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
LE L L +N I+ + L L L L +N + ++ L LP L LDLS N+
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL---RLPRLLLLDLSHNS 180
Query: 249 MTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
+ + L +N+ L L+G ER+
Sbjct: 181 LLALEPGILDT-ANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL-ERVPP-VIRG 237
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPI-DRLQELEISG 367
L ++ + N ++ ++ P G L + + N +L+ L + RL+ L +
Sbjct: 238 LRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAAR 297
Query: 368 NPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESE 427
NPF C C L W ++S T E+ +C P + G L +++ ++
Sbjct: 298 NPFNCVCPLSWFGPWVRESHVTLASP-----------EETRCHFPPKNAGRLLLELDYAD 346
Query: 428 FGC 430
FGC
Sbjct: 347 FGC 349
Score = 65.7 bits (153), Expect = 4e-10
Identities = 71/255 (27%), Positives = 111/255 (43%), Gaps = 31/255 (12%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLD 75
CP C C + C VP + P+ + + N I L +F L +LD
Sbjct: 24 CPSGCQCSQP-QTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLD 82
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I L S F+ + + +L+L+ N L EI+N +
Sbjct: 83 LSQNQIASLPSGVFQPLANLSNLDLTANRLH---------------------EITN---E 118
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
TFR L LERL NR+ +P F+ L L L L++N + +P L L LD
Sbjct: 119 TFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLP---RLLLLD 175
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
LS N + + G+ ++ L L ++ +D+ F L +L LD+SDN + +P
Sbjct: 176 LSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP-P 233
Query: 256 ALSKLSNLSHLYLSG 270
+ L L+ L L+G
Sbjct: 234 VIRGLRGLTRLRLAG 248
Score = 37.5 bits (83), Expect = 0.12
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 3/131 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L +LD+S+N +L L + + L L+ L++LD+ F ++
Sbjct: 170 RLLLLDLSHNSLLAL-EPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
Query: 130 SNIHVQTFRDLSALERLDFSNN-RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+ R L L RL + N R+ PE L++L+ L + N S+ +P G
Sbjct: 229 ERVP-PVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLF 287
Query: 189 IHLEYLDLSEN 199
L L + N
Sbjct: 288 PRLRLLAAARN 298
>AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 380
Score = 72.9 bits (171), Expect = 3e-12
Identities = 40/120 (33%), Positives = 61/120 (50%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
ERL+ + N + F L L++L L N I + + LE LDLSEN IQ
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQA 123
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ R +LK+L L+ N I +++ F +L L L L++NN+T IP S+ + + L
Sbjct: 124 IPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKL 183
Score = 64.9 bits (151), Expect = 7e-10
Identities = 46/178 (25%), Positives = 73/178 (41%), Gaps = 5/178 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L+LS N ++ + + AF G
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRGATDL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 136 KNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 193
Score = 57.2 bits (132), Expect = 1e-07
Identities = 36/121 (29%), Positives = 54/121 (44%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N+I IP
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIPRKAFRGA 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L +N I + L+ L+ L LNNN I ++ F+ +P LR L N+
Sbjct: 133 TDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNH 192
Query: 249 M 249
+
Sbjct: 193 L 193
Score = 52.4 bits (120), Expect = 4e-06
Identities = 32/100 (32%), Positives = 47/100 (47%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ LDL+ N I+++
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQAIP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ F L++L L N ++ I A L L L L+
Sbjct: 126 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLN 165
Score = 51.2 bits (117), Expect = 9e-06
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 2/137 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D S N + + F + LK L L N I I + LE L L+ N I +
Sbjct: 115 DLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPV 174
Query: 207 HGLPFLKELKHLDLNNN 223
+ +L+ L++N
Sbjct: 175 SSFNHMPKLRTFRLHSN 191
Score = 49.2 bits (112), Expect = 4e-05
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 3/125 (2%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 258 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 315
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 316 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 375
Query: 136 TFRDL 140
F+DL
Sbjct: 376 AFQDL 380
Score = 46.4 bits (105), Expect = 3e-04
Identities = 26/77 (33%), Positives = 43/77 (55%)
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
E L+L+ N I ++ ++ LK+L+ L L N I +V++ F + L LDLS+N +
Sbjct: 64 ERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLSENAIQA 123
Query: 252 IPTSALSKLSNLSHLYL 268
IP A ++L +L L
Sbjct: 124 IPRKAFRGATDLKNLQL 140
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/73 (35%), Positives = 36/73 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 297 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 356
Query: 189 IHLEYLDLSENLI 201
L+ L L+ N I
Sbjct: 357 YTLQLLLLNANKI 369
Score = 41.9 bits (94), Expect = 0.006
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 41/220 (18%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L LS
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLDLS--- 117
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 118 ----------------------ENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 154
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 155 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTIGL 214
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+ +CSGP L+G+ ++ +SEF CS
Sbjct: 215 FT--------------QCSGPASLRGLNVAEVQKSEFSCS 240
Score = 39.5 bits (88), Expect = 0.031
Identities = 24/99 (24%), Positives = 44/99 (44%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 282 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 341
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPL 164
+I+++ F L L+ L + N++ P+ F+ L
Sbjct: 342 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
Score = 34.7 bits (76), Expect = 0.88
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
I+ R + IP ANL + L+L N I+ + ++L+ +DL+NN I +
Sbjct: 268 IVDCRGKGLTAIP-ANLPETMTEIRLEL--NGIKSIPPGAFSPYRKLRRIDLSNNQIAEI 324
Query: 229 DQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
F L SL L L N +T +P L L L L+
Sbjct: 325 APDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 365
Score = 32.3 bits (70), Expect = 4.7
Identities = 26/91 (28%), Positives = 38/91 (41%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 290 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 349
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
+ F L +L+ L L+ N + I A L
Sbjct: 350 RGVFGGLYTLQLLLLNANKINCIRPDAFQDL 380
>BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 72.5 bits (170), Expect = 4e-12
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+HN +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 525 VLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 584
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 585 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 644
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 645 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLR 704
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 705 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 750
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S+NK LDL E+ F + L+LS N F
Sbjct: 501 LRLSHNCISQAVNGSQFLPLTGLQVLDLSHNK-LDLYHEHSFTELPRLEALDLSYNSQPF 559
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 619
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 620 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 679
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 680 EVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 733
Score = 56.0 bits (129), Expect = 3e-07
Identities = 92/357 (25%), Positives = 143/357 (40%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 463 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 522
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S+N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 523 LQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 582
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 583 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 640
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 641 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQL-KALTNGSLPA 699
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 700 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 758
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 759 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 804
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAI--DNL-LYAFNLYTQLTVLDISYNKILDLGSEN 88
C A LE+ P L L NLTH ++ +NL + NL + L L +SYN+I+ L E+
Sbjct: 184 CRQA-LEVAPGAL---LGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPED 239
Query: 89 FESNSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNI 132
+ + +R L++ N + +L D F +S +
Sbjct: 240 LANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWL 299
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL----- 185
+ FR L L LD S N L +T F+ L+ L+ L+L N + A+L
Sbjct: 300 NASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPS 359
Query: 186 -GFVIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLR 240
G ++ L+ LD+ + + + L L L+ L L N I QLG F + P LR
Sbjct: 360 FGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLR 418
Query: 241 HLDLSDNNMT 250
++DLSDN ++
Sbjct: 419 YVDLSDNRIS 428
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 469 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 528
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 529 SHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 588
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 589 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 647
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 648 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Score = 37.1 bits (82), Expect = 0.17
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 112 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLI----SLSLSHTNILMLDSASLAGLH 167
Query: 214 ELKHLDLNNNIIE--------SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L +L HL L NN+T++P + S L L
Sbjct: 168 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYL 225
>AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein.
Length = 1032
Score = 72.5 bits (170), Expect = 4e-12
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+HN +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 525 VLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 584
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 585 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 644
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 645 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLR 704
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 705 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 750
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S+NK LDL E+ F + L+LS N F
Sbjct: 501 LRLSHNCISQAVNGSQFLPLTGLQVLDLSHNK-LDLYHEHSFTELPRLEALDLSYNSQPF 559
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 619
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 620 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 679
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 680 EVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 733
Score = 56.0 bits (129), Expect = 3e-07
Identities = 92/357 (25%), Positives = 143/357 (40%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 463 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 522
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S+N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 523 LQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 582
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 583 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 640
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 641 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQL-KALTNGSLPA 699
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 700 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 758
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 759 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 804
Score = 47.6 bits (108), Expect = 1e-04
Identities = 65/247 (26%), Positives = 106/247 (42%), Gaps = 30/247 (12%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFES 91
C A LE+ P L +L +L+ + + NL + L L +SYN+I+ L E+ +
Sbjct: 184 CRQA-LEVAPGALLGLGSLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLAN 242
Query: 92 NSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ +R L++ N + +L D F +S ++
Sbjct: 243 LTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNAS 302
Query: 136 TFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL------GF 187
FR L L LD S N L +T + L+ L+ L+L N + A+L G
Sbjct: 303 WFRGLGNLRVLDLSENFLYKCITKTKALQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGS 362
Query: 188 VIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLRHLD 243
++ L+ LD+ + + + L L L+ L L N I QLG F + P LR++D
Sbjct: 363 LVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLRYVD 421
Query: 244 LSDNNMT 250
LSDN ++
Sbjct: 422 LSDNRIS 428
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 469 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 528
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 529 SHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 588
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 589 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 647
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 648 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Score = 38.3 bits (85), Expect = 0.071
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 112 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLIS----LSLSHTNILMLDSASLAGLH 167
Query: 214 ELKHLDLNNNIIES--------VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L SL HL L NN+T++P + S L L
Sbjct: 168 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGSLTHLSLKYNNLTVVPRNLPSSLEYL 225
>AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 form
B protein.
Length = 975
Score = 72.5 bits (170), Expect = 4e-12
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+HN +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 468 VLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 527
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 528 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 587
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 588 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLR 647
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 648 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 693
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S+NK LDL E+ F + L+LS N F
Sbjct: 444 LRLSHNCISQAVNGSQFLPLTGLQVLDLSHNK-LDLYHEHSFTELPRLEALDLSYNSQPF 502
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 503 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 562
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 563 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 622
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 623 EVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 676
Score = 56.0 bits (129), Expect = 3e-07
Identities = 92/357 (25%), Positives = 143/357 (40%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 406 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 465
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S+N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 466 LQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 525
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 526 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 583
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 584 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQL-KALTNGSLPA 642
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 643 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 701
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 702 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 747
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAI--DNL-LYAFNLYTQLTVLDISYNKILDLGSEN 88
C A LE+ P L L NLTH ++ +NL + NL + L L +SYN+I+ L E+
Sbjct: 127 CRQA-LEVAPGAL---LGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPED 182
Query: 89 FESNSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNI 132
+ + +R L++ N + +L D F +S +
Sbjct: 183 LANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWL 242
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL----- 185
+ FR L L LD S N L +T F+ L+ L+ L+L N + A+L
Sbjct: 243 NASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPS 302
Query: 186 -GFVIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLR 240
G ++ L+ LD+ + + + L L L+ L L N I QLG F + P LR
Sbjct: 303 FGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLR 361
Query: 241 HLDLSDNNMT 250
++DLSDN ++
Sbjct: 362 YVDLSDNRIS 371
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 412 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 471
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 472 SHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 531
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 532 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 590
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 591 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 629
Score = 37.1 bits (82), Expect = 0.17
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 55 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLI----SLSLSHTNILMLDSASLAGLH 110
Query: 214 ELKHLDLNNNIIE--------SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L +L HL L NN+T++P + S L L
Sbjct: 111 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYL 168
>AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 form
A protein.
Length = 1032
Score = 72.5 bits (170), Expect = 4e-12
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+HN +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 525 VLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 584
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 585 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 644
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 645 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLR 704
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 705 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 750
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S+NK LDL E+ F + L+LS N F
Sbjct: 501 LRLSHNCISQAVNGSQFLPLTGLQVLDLSHNK-LDLYHEHSFTELPRLEALDLSYNSQPF 559
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 619
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 620 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 679
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 680 EVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 733
Score = 56.0 bits (129), Expect = 3e-07
Identities = 92/357 (25%), Positives = 143/357 (40%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 463 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 522
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S+N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 523 LQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 582
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 583 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 640
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 641 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQL-KALTNGSLPA 699
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 700 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 758
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 759 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 804
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAI--DNL-LYAFNLYTQLTVLDISYNKILDLGSEN 88
C A LE+ P L L NLTH ++ +NL + NL + L L +SYN+I+ L E+
Sbjct: 184 CRQA-LEVAPGAL---LGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPED 239
Query: 89 FESNSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNI 132
+ + +R L++ N + +L D F +S +
Sbjct: 240 LANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWL 299
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL----- 185
+ FR L L LD S N L +T F+ L+ L+ L+L N + A+L
Sbjct: 300 NASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPS 359
Query: 186 -GFVIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLR 240
G ++ L+ LD+ + + + L L L+ L L N I QLG F + P LR
Sbjct: 360 FGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLR 418
Query: 241 HLDLSDNNMT 250
++DLSDN ++
Sbjct: 419 YVDLSDNRIS 428
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 469 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 528
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 529 SHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 588
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 589 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 647
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 648 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Score = 37.1 bits (82), Expect = 0.17
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 112 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLI----SLSLSHTNILMLDSASLAGLH 167
Query: 214 ELKHLDLNNNIIE--------SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L +L HL L NN+T++P + S L L
Sbjct: 168 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYL 225
>AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 72.5 bits (170), Expect = 4e-12
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+HN +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 525 VLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 584
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 585 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 644
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 645 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLR 704
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 705 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 750
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/234 (29%), Positives = 100/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S+NK LDL E+ F + L+LS N F
Sbjct: 501 LRLSHNCISQAVNGSQFLPLTGLQVLDLSHNK-LDLYHEHSFTELPRLEALDLSYNSQPF 559
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 619
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 620 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 679
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 680 EVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 733
Score = 56.0 bits (129), Expect = 3e-07
Identities = 92/357 (25%), Positives = 143/357 (40%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 463 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 522
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S+N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 523 LQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 582
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 583 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 640
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 641 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQL-KALTNGSLPA 699
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 700 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 758
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 759 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 804
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAI--DNL-LYAFNLYTQLTVLDISYNKILDLGSEN 88
C A LE+ P L L NLTH ++ +NL + NL + L L +SYN+I+ L E+
Sbjct: 184 CRQA-LEVAPGAL---LGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPED 239
Query: 89 FESNSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNI 132
+ + +R L++ N + +L D F +S +
Sbjct: 240 LANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWL 299
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL----- 185
+ FR L L LD S N L +T F+ L+ L+ L+L N + A+L
Sbjct: 300 NASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPS 359
Query: 186 -GFVIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLR 240
G ++ L+ LD+ + + + L L L+ L L N I QLG F + P LR
Sbjct: 360 FGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLR 418
Query: 241 HLDLSDNNMT 250
++DLSDN ++
Sbjct: 419 YVDLSDNRIS 428
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 469 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 528
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 529 SHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 588
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 589 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 647
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 648 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Score = 37.1 bits (82), Expect = 0.17
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 112 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLI----SLSLSHTNILMLDSASLAGLH 167
Query: 214 ELKHLDLNNNIIE--------SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L +L HL L NN+T++P + S L L
Sbjct: 168 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYL 225
>BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein
protein.
Length = 693
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 348 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 407
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ LN+ N L ++ + I ++ D
Sbjct: 408 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 464
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 465 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 521
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 522 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 580
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 581 YLPK--SLLHLVLLG 593
>BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ LN+ N L ++ + I ++ D
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 436
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 437 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 493
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 494 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 552
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 553 YLPK--SLLHLVLLG 565
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 72.1 bits (169), Expect = 5e-12
Identities = 71/258 (27%), Positives = 102/258 (39%), Gaps = 27/258 (10%)
Query: 12 AAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQL 71
AA LC C CD R C+ L VP L+ AF QL
Sbjct: 24 AAPPLCAAPCSCDGD-RRVDCSGKGLTAVPEGLS------------------AFTQALQL 64
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
D+S+ + + E++ L L NN LK + +A G I++
Sbjct: 65 AGNDLSF-----IHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS 119
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ +F L L L +N L L +L+ L+L N I IP + L
Sbjct: 120 VPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSL 179
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
L L N I+ +S+H L L+ LDLN N + Q +LPSL+ L N++++
Sbjct: 180 VVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQ-AIKALPSLKELGFHSNSISV 238
Query: 252 IPTSAL--SKLSNLSHLY 267
IP A + L HLY
Sbjct: 239 IPDGAFDGNPLLRTIHLY 256
Score = 70.1 bits (164), Expect = 2e-11
Identities = 62/230 (26%), Positives = 100/230 (43%), Gaps = 5/230 (2%)
Query: 140 LSAL-ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
LSA + L + N L P+ L LK+L+L+NN + +PS + + L+ L L
Sbjct: 55 LSAFTQALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDA 114
Query: 199 NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
N I V L +L+HL L++N + V +LP+L+ L L+ N ++ IP A +
Sbjct: 115 NHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFT 174
Query: 259 KLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMN 318
LS+L L+L E +A +L+++ +
Sbjct: 175 NLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE--FPQAIKALPSLKELGFH 232
Query: 319 DNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISG 367
N + +P F GNP L I++ +N L + S F + L L I G
Sbjct: 233 SN-SISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRG 281
Score = 66.9 bits (156), Expect = 2e-10
Identities = 56/216 (25%), Positives = 91/216 (42%), Gaps = 9/216 (4%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
++L +N + A L L N I + F+ N +R ++L +N L +
Sbjct: 206 LDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGN 265
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSA---LERLDFSNNRLVTFEPETFEPLSSL 167
AF + VQ F +L+ LE L + ++ + + L
Sbjct: 266 SAFHNLSDLHSLVIRGASM----VQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKML 321
Query: 168 KILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIES 227
+ L L N+I D+PS N LE + L N I Q+ L L+ LDL+ N+I
Sbjct: 322 RTLDLSYNNIRDLPSFNGCHA--LEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHE 379
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
+ F +L + +LD+S N +T PT L+ L+ L
Sbjct: 380 IHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQL 415
Score = 53.2 bits (122), Expect = 2e-06
Identities = 42/125 (33%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 145 RLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
R+D S L T PE + + L L N + I L + L+ L L N ++ V
Sbjct: 40 RVDCSGKGL-TAVPEGLSAFT--QALQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTV 96
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
+ L L+ L L+ N I SV + F L LRHL L DN++T +P LS L L
Sbjct: 97 PSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQ 156
Query: 265 HLYLS 269
L L+
Sbjct: 157 ALTLA 161
Score = 51.2 bits (117), Expect = 9e-06
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 7/222 (3%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+++L +N I +L + F+ L LD++YN + + + ++ ++ L +N + +
Sbjct: 181 VLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF-PQAIKALPSLKELGFHSNSISVI 239
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF G +S + F +LS L L +V P + L+
Sbjct: 240 PDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH-LE 298
Query: 169 ILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV-SRHGLPFLKELKHLDLNNNIIES 227
L+L I IP+ L LDLS N I+ + S +G L+E+ L N I
Sbjct: 299 SLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEIS---LQRNQIYQ 355
Query: 228 VDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ + F L SLR LDLS N + I + A + L +++L +S
Sbjct: 356 IKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVS 397
Score = 48.4 bits (110), Expect = 7e-05
Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L LD+SYN I DL S F + ++L N + ++ + F G I
Sbjct: 321 LRTLDLSYNNIRDLPS--FNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIH 378
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
IH + F L + LD S N L +F E L+ LK++
Sbjct: 379 EIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLV 418
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 3/177 (1%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ L + + N + +G+ F + S++ L + + + + G
Sbjct: 243 AFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPN-LTGTVHLESLT 301
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSA 183
+IS+I ++ L LD S N + +F +L+ +SL+ N I I
Sbjct: 302 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP--SFNGCHALEEISLQRNQIYQIKEG 359
Query: 184 NLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLR 240
+I L LDLS NLI ++ L + +LD++ N + S G + L L+
Sbjct: 360 TFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLK 416
Score = 42.7 bits (96), Expect = 0.003
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
+F ALE + N++ + TF+ L SL+IL L N I +I S + + LD
Sbjct: 336 SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLD 395
Query: 196 LSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+S N + GL L +LK L N + E++ F +L SL
Sbjct: 396 VSFNELTSFPTEGLNGLNQLK-LVGNFKLKEALAAKDFVNLRSL 438
>AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ LN+ N L ++ + I ++ D
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 436
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 437 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 493
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 494 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 552
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 553 YLPK--SLLHLVLLG 565
>AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ LN+ N L ++ + I ++ D
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 436
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 437 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 493
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 494 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 552
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 553 YLPK--SLLHLVLLG 565
>AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix
protein protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/255 (28%), Positives = 111/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ LN+ N L ++ + I ++ D
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 436
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 437 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 493
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 494 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 552
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 553 YLPK--SLLHLVLLG 565
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 71.7 bits (168), Expect = 6e-12
Identities = 60/209 (28%), Positives = 88/209 (42%), Gaps = 4/209 (1%)
Query: 52 NLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
NLTH NLL + +L L +S N + L E ++R L+L+ N L L
Sbjct: 79 NLTHLPA-NLLQGAS---KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSG 134
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F ++ + V L AL LD S NRL P + L+ L
Sbjct: 135 LFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLD 194
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N + +P L + LE L L N +Q + + L +L++L LN N + V
Sbjct: 195 LGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAG 254
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
F L L LDLS+N++ +P + L
Sbjct: 255 AFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/142 (28%), Positives = 67/142 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
++++ + S L+ L S+N L + PE P+ L++L L N++ +PS
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L EN ++ + L LK L HLDL+ N + + + LR LDL +N
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 249 MTLIPTSALSKLSNLSHLYLSG 270
+ +P L L L+L G
Sbjct: 200 LETLPPDLLRGPLQLERLHLEG 221
Score = 52.0 bits (119), Expect = 5e-06
Identities = 45/196 (22%), Positives = 80/196 (40%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + + + L + + S+++ L+LS+N L+ L + ++ +
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ + L+ L N+L E L +L L L N + +P L L
Sbjct: 133 SGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL EN ++ + L +L+ L L N ++ + + P LR+L L+ N + +
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVA 252
Query: 254 TSALSKLSNLSHLYLS 269
A L L L LS
Sbjct: 253 AGAFQGLRQLDMLDLS 268
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/174 (22%), Positives = 71/174 (40%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
HL + L L + G + ++ + R + L LD + N L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
F+ ++L L L+ N + + + L + L +LDLS N ++++ L L+
Sbjct: 132 PSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LDL N +E++ L L L N + ++ L +L +L+L+G
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 71.7 bits (168), Expect = 6e-12
Identities = 56/206 (27%), Positives = 87/206 (42%), Gaps = 1/206 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL ++ + +T + + +N I L + F++ +++ L L NN + + AF G
Sbjct: 54 NLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSL 113
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I+ + F DL LE L +N L P TF L+SL +L L NN +
Sbjct: 114 TKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTR 173
Query: 180 IPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+P L + L +LDL N I + L L + N I +++ F L
Sbjct: 174 LPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQK 233
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLS 264
L LDL N + +P L LS
Sbjct: 234 LDELDLGSNKIENLPPLIFKDLKELS 259
Score = 45.2 bits (102), Expect = 6e-04
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F++ L++L NN++ + F L+SL L L +N I + + LE+L +
Sbjct: 83 FKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLII 142
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESV-DQLGFHSLPSLRHLDLSDNNMTLIPTS 255
+N + ++S L L L L NN++ + D+ +P L LDL N++ +
Sbjct: 143 EDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNL 202
Query: 256 ALSKLSNLSHLYL 268
SNL+ L +
Sbjct: 203 TFISCSNLTVLVM 215
Score = 39.1 bits (87), Expect = 0.041
Identities = 51/219 (23%), Positives = 77/219 (35%), Gaps = 7/219 (3%)
Query: 156 FEPETFEPL-SSLKILSLRNNSILDIPSANLGFV----IHLEYLDLSENLIQQVSRHGLP 210
FE ET E L S+ + L LD NL V ++ + L NLI+++
Sbjct: 25 FEAETPECLVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFK 84
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+L+ L L NN I S+ F L SL L LS N +T + L L L +
Sbjct: 85 NYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIED 144
Query: 271 XXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRL 330
D L + + N + +
Sbjct: 145 NHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGN-HIHNLRNLT 203
Query: 331 FHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
F LT + M+ N + L + F P+ +L EL++ N
Sbjct: 204 FISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSN 242
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 71.7 bits (168), Expect = 6e-12
Identities = 60/209 (28%), Positives = 88/209 (42%), Gaps = 4/209 (1%)
Query: 52 NLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
NLTH NLL + +L L +S N + L E ++R L+L+ N L L
Sbjct: 79 NLTHLPA-NLLQGAS---KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSG 134
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F ++ + V L AL LD S NRL P + L+ L
Sbjct: 135 LFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLD 194
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N + +P L + LE L L N +Q + + L +L++L LN N + V
Sbjct: 195 LGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAG 254
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
F L L LDLS+N++ +P + L
Sbjct: 255 AFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/142 (28%), Positives = 67/142 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
++++ + S L+ L S+N L + PE P+ L++L L N++ +PS
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L EN ++ + L LK L HLDL+ N + + + LR LDL +N
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 249 MTLIPTSALSKLSNLSHLYLSG 270
+ +P L L L+L G
Sbjct: 200 LETLPPDLLRGPLQLERLHLEG 221
Score = 52.0 bits (119), Expect = 5e-06
Identities = 45/196 (22%), Positives = 80/196 (40%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + + + L + + S+++ L+LS+N L+ L + ++ +
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ + L+ L N+L E L +L L L N + +P L L
Sbjct: 133 SGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL EN ++ + L +L+ L L N ++ + + P LR+L L+ N + +
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVA 252
Query: 254 TSALSKLSNLSHLYLS 269
A L L L LS
Sbjct: 253 AGAFQGLRQLDMLDLS 268
Score = 43.6 bits (98), Expect = 0.002
Identities = 39/174 (22%), Positives = 71/174 (40%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
HL + L L + G + ++ + R + L LD + N L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
F+ ++L L L+ N + + + L + L +LDLS N ++++ L L+
Sbjct: 132 PSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LDL N +E++ L L L N + ++ L +L +L+L+G
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/209 (28%), Positives = 88/209 (42%), Gaps = 4/209 (1%)
Query: 52 NLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
NLTH NLL + +L L +S N + L E ++R L+L+ N L L
Sbjct: 79 NLTHLPA-NLLQGAS---KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPG 134
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F ++ + V L AL LD S NRL P + L+ L
Sbjct: 135 LFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLD 194
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N + +P L + LE L L N +Q + + L +L++L LN N + V
Sbjct: 195 LGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAG 254
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
F L L LDLS+N++ +P + L
Sbjct: 255 AFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 65.7 bits (153), Expect = 4e-10
Identities = 40/142 (28%), Positives = 66/142 (46%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
++++ + S L+ L S+N L + PE P+ L++L L N++ +P
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L EN ++ + L LK L HLDL+ N + + + LR LDL +N
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 249 MTLIPTSALSKLSNLSHLYLSG 270
+ +P L L L+L G
Sbjct: 200 LETLPPDLLRGPLQLERLHLEG 221
Score = 52.0 bits (119), Expect = 5e-06
Identities = 45/196 (22%), Positives = 80/196 (40%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + + + L + + S+++ L+LS+N L+ L + ++ +
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ + L+ L N+L E L +L L L N + +P L L
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL EN ++ + L +L+ L L N ++ + + P LR+L L+ N + +
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVA 252
Query: 254 TSALSKLSNLSHLYLS 269
A L L L LS
Sbjct: 253 AGAFQGLRQLDMLDLS 268
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/174 (22%), Positives = 72/174 (41%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
HL + L L + G + ++ + R + L LD + N L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P F+ ++L L L+ N + + + L + L +LDLS N ++++ L L+
Sbjct: 132 PPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LDL N +E++ L L L N + ++ L +L +L+L+G
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Score = 32.7 bits (71), Expect = 3.6
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
+PP LF + L + +K N LE LE S + L L++SGN
Sbjct: 131 LPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
>AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein.
Length = 798
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 56 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 115
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 116 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 175
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 176 ITTIPVSSFNHMPKL 190
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 40 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 97
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 98 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 157
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 158 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 498 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 554
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 555 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 614
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 615 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 3 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 58
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 59 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 118
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 119 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 178
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 179 IPVSSFNHMPKLRTFRLHSN 198
Score = 55.2 bits (127), Expect = 6e-07
Identities = 34/101 (33%), Positives = 52/101 (51%)
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D SNN++ P+ F+ L SL L L N I D+P G + L+ L L+ N I +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 147
Score = 52.0 bits (119), Expect = 5e-06
Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 13/173 (7%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVL- 74
CP C C + + C L +P L T + L N I ++ AF+ Y +L +
Sbjct: 265 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIR 322
Query: 75 ---------DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
D+S N+I ++ + F+ + L L N + L + F G
Sbjct: 323 PLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 382
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
+I+ I F+DL L L +N++ + TF L +++ L L N +
Sbjct: 383 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 435
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 102
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 103 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 161
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 162 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 219
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 220 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 247
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 87 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 146
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 147 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 265 HLYL 268
L L
Sbjct: 658 TLNL 661
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 554 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 613
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 614 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 376 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 435 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 480
Query: 431 SS 432
S+
Sbjct: 481 SA 482
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 513 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 569
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 570 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 629
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 630 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 534 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 593
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 594 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 649
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 650 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 705
>AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 505 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 561
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 562 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 621
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 622 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 734 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 852 FADVTSLSHLAIGANPL 868
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 164
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 265 HLYL 268
L L
Sbjct: 665 TLNL 668
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 766 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 561 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 620
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 621 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 877
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 878 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 377
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 378 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 437
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 383 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 441
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 442 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 487
Query: 431 SS 432
S+
Sbjct: 488 SA 489
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 520 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 412
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 601 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 656
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 657 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 712
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 839
Query: 269 SG 270
G
Sbjct: 840 HG 841
>AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 505 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 561
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 562 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 621
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 622 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 734 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 852 FADVTSLSHLAIGANPL 868
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 164
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 265 HLYL 268
L L
Sbjct: 665 TLNL 668
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 766 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 561 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 620
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 621 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 877
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 878 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 377
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 378 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 437
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 383 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 441
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 442 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 487
Query: 431 SS 432
S+
Sbjct: 488 SA 489
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 520 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 412
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 601 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 656
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 657 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 712
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 839
Query: 269 SG 270
G
Sbjct: 840 HG 841
>AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 409
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 164
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 39.1 bits (87), Expect = 0.041
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLN 99
+S N+I ++ + F+ + L+
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLH 363
>AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 782
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 56 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 115
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 116 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 175
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 176 ITTIPVSSFNHMPKL 190
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 40 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 97
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 98 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 157
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 158 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 498 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 554
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 555 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 614
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 615 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 3 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 58
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 59 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 118
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 119 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 178
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 179 IPVSSFNHMPKLRTFRLHSN 198
Score = 55.2 bits (127), Expect = 6e-07
Identities = 34/101 (33%), Positives = 52/101 (51%)
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
D SNN++ P+ F+ L SL L L N I D+P G + L+ L L+ N I +
Sbjct: 332 DLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRP 391
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 392 DAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 432
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 49 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 108
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 109 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 147
Score = 52.0 bits (119), Expect = 5e-06
Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 13/173 (7%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVL- 74
CP C C + + C L +P L T + L N I ++ AF+ Y +L +
Sbjct: 265 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIC 322
Query: 75 ---------DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
D+S N+I ++ + F+ + L L N + L + F G
Sbjct: 323 PLSFCSPCRDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLN 382
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
+I+ I F+DL L L +N++ + TF L +++ L L N +
Sbjct: 383 ANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 435
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 44 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 102
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 103 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 161
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 162 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 219
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 220 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 247
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 87 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 146
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 147 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 200
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 538 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 597
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 598 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 657
Query: 265 HLYL 268
L L
Sbjct: 658 TLNL 661
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 554 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 613
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 614 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 376 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 434
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 435 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 480
Query: 431 SS 432
S+
Sbjct: 481 SA 482
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 513 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 569
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 570 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 629
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 630 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 664
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 534 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 593
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 594 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 649
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 650 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 705
>AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1461
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 505 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 561
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 562 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 621
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 622 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 734 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 852 FADVTSLSHLAIGANPL 868
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 164
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 265 HLYL 268
L L
Sbjct: 665 TLNL 668
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 766 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 561 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 620
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 621 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 877
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 878 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 377
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 378 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 437
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 383 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 441
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 442 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 487
Query: 431 SS 432
S+
Sbjct: 488 SA 489
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 520 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 412
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 601 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 656
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 657 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 712
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 839
Query: 269 SG 270
G
Sbjct: 840 HG 841
>AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1
(Drosophila) protein.
Length = 1534
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 505 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 561
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 562 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 621
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 622 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 64.5 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 734 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 852 FADVTSLSHLAIGANPL 868
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 164
Score = 51.6 bits (118), Expect = 7e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 265 HLYL 268
L L
Sbjct: 665 TLNL 668
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 766 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 561 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 620
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 621 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 877
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 878 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 377
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 378 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 437
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 383 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 441
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 442 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 487
Query: 431 SS 432
S+
Sbjct: 488 SA 489
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 520 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 412
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 601 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 656
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 657 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 712
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 839
Query: 269 SG 270
G
Sbjct: 840 HG 841
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 71.3 bits (167), Expect = 8e-12
Identities = 60/209 (28%), Positives = 88/209 (42%), Gaps = 4/209 (1%)
Query: 52 NLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKD 111
NLTH NLL + +L L +S N + L E ++R L+L+ N L L
Sbjct: 79 NLTHLPA-NLLQGAS---KLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPG 134
Query: 112 AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILS 171
F ++ + V L AL LD S NRL P + L+ L
Sbjct: 135 LFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLD 194
Query: 172 LRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
L N + +P L + LE L L N +Q + + L +L++L LN N + V
Sbjct: 195 LGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAG 254
Query: 232 GFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
F L L LDLS+N++ +P + L
Sbjct: 255 AFQGLRQLDMLDLSNNSLASVPEGLWASL 283
Score = 65.7 bits (153), Expect = 4e-10
Identities = 40/142 (28%), Positives = 66/142 (46%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
++++ + S L+ L S+N L + PE P+ L++L L N++ +P
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L+ L L EN ++ + L LK L HLDL+ N + + + LR LDL +N
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 249 MTLIPTSALSKLSNLSHLYLSG 270
+ +P L L L+L G
Sbjct: 200 LETLPPDLLRGPLQLERLHLEG 221
Score = 52.0 bits (119), Expect = 5e-06
Identities = 45/196 (22%), Positives = 80/196 (40%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + + + L + + S+++ L+LS+N L+ L + ++ +
Sbjct: 73 LAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLP 132
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
F+ + L+ L N+L E L +L L L N + +P L L
Sbjct: 133 PGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRT 192
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
LDL EN ++ + L +L+ L L N ++ + + P LR+L L+ N + +
Sbjct: 193 LDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVA 252
Query: 254 TSALSKLSNLSHLYLS 269
A L L L LS
Sbjct: 253 AGAFQGLRQLDMLDLS 268
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/174 (22%), Positives = 72/174 (41%)
Query: 97 HLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
HL + L L + G + ++ + R + L LD + N L
Sbjct: 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL 131
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P F+ ++L L L+ N + + + L + L +LDLS N ++++ L L+
Sbjct: 132 PPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLR 191
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
LDL N +E++ L L L N + ++ L +L +L+L+G
Sbjct: 192 TLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNG 245
Score = 32.7 bits (71), Expect = 3.6
Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGN 368
+PP LF + L + +K N LE LE S + L L++SGN
Sbjct: 131 LPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN 174
>AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein.
Length = 1618
Score = 71.3 bits (167), Expect = 8e-12
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 157 ITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 216
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 217 QALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNN 276
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 277 ITTIPVSSFNHMPKL 291
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 589 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 645
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 646 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 705
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 706 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 755
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 141 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERL 198
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 199 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEE 258
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 259 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 64.1 bits (149), Expect = 1e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 104 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 159
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 160 IHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 219
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 220 SRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 279
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 280 IPVSSFNHMPKLRTFRLHSN 299
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 366 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 423
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 424 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 483
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 484 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 526
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 405 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 464
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 465 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 523
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 818 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 875
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 876 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 935
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 936 FADVTSLSHLAIGANPL 952
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 390 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 449
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 450 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 509
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 510 TSLRAIQTLHLAQN 523
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 150 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLNRNQLHMLP 209
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 210 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQL 248
Score = 52.4 bits (120), Expect = 4e-06
Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + ++ A + L L L+
Sbjct: 145 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGVVERGAFDDMKELERLRLN-RN 203
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 204 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKN-QISCIEEGAFR 262
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 263 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 320
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 321 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 348
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 188 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQ 247
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 248 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 301
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 629 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 688
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 689 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 748
Query: 265 HLYL 268
L L
Sbjct: 749 TLNL 752
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 850 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 908
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 909 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 945
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 645 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 704
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 705 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 755
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 907 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 961
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 962 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 998
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 403 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 461
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 462 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 521
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 467 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 525
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 526 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 571
Query: 431 SS 432
S+
Sbjct: 572 SA 573
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 604 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 660
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 661 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 720
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 721 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 755
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 398 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 457
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 458 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 496
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 625 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 684
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 685 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 740
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 741 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 796
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 864 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 923
Query: 269 SG 270
G
Sbjct: 924 HG 925
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2
(Drosophila) protein.
Length = 1529
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
Query: 88 NFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLD 147
N N+E L+L+ N + R+ K F G +IS I F+DL LERL
Sbjct: 52 NIPRNTE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLR 109
Query: 148 FSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRH 207
+ N L F F + L L L N I IP + ++ L L N I +
Sbjct: 110 LNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDG 169
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L++L+ L LNNN I + F+ +P LR L NN+
Sbjct: 170 AFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I + AF+ Y +L +D
Sbjct: 273 CPAACTCSNNI--VDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRID 330
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I +L + F+ + L L N + L K F G +I+ + V
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N+L T TF PL +++ + L N +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFI 433
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N L+++P + + T + L N + + Y LT++D+
Sbjct: 727 CPTECTCLDTV--VRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDL 784
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S N+I L +++F + +++ L LS N L+ + F G +IS +
Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844
Query: 137 FRDLSALERLDFSNNRL 153
F DLSAL L N L
Sbjct: 845 FNDLSALSHLAIGANPL 861
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 3/188 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQL 71
A CP +C C + C L VP + ++L N I + F L
Sbjct: 24 APQACPAQCSCSGS--TVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
VL + NKI + F+ E+ L L+ N L+ + F+G +I
Sbjct: 82 RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQA 141
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I + FR ++ L N++ E F L L++L+L NN+I + A+ + L
Sbjct: 142 IPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKL 201
Query: 192 EYLDLSEN 199
L N
Sbjct: 202 RTFRLHSN 209
Score = 60.9 bits (141), Expect = 1e-08
Identities = 40/135 (29%), Positives = 62/135 (45%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L N++ T E F+ L L+ L L N + P
Sbjct: 67 ITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGT 126
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R ++K+L L+ N I ++ F +L L L L++NN
Sbjct: 127 AKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNN 186
Query: 249 MTLIPTSALSKLSNL 263
+T + ++ + + L
Sbjct: 187 ITRLSVASFNHMPKL 201
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/99 (34%), Positives = 47/99 (47%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + HL L L EN I + R LKEL+ L LN N ++
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F L LDLS+N + IP A ++ +L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQL 158
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 24/187 (12%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLT 72
A CP +C C+ C+N L +P + + L +N + T
Sbjct: 502 ADLACPEKCRCEGT--TVDCSNQKLNKIPEHIPQYTAELRLNNN-------------EFT 546
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
VL+ + F+ ++R +N SNN + +++ AF G + N+
Sbjct: 547 VLE---------ATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F+ L +L+ L +NR+ ++F LSS+++LSL +N I + + L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 193 YLDLSEN 199
L+L N
Sbjct: 658 TLNLLAN 664
Score = 51.6 bits (118), Expect = 7e-06
Identities = 32/134 (23%), Positives = 61/134 (45%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + L DAF G
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + F L +L+ L + N++ + F+ L +L +LSL +N + I
Sbjct: 357 GNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Query: 186 GFVIHLEYLDLSEN 199
+ ++ + L++N
Sbjct: 417 SPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 31/111 (27%), Positives = 54/111 (48%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L R+D SNN++ P+ F+ L SL L L N I ++P + + L+ L L
Sbjct: 320 FSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLL 379
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ N I + L L L L +N ++++ + F L +++ + L+ N
Sbjct: 380 NANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L HL +DLS N I +S + +L L L+ N + +
Sbjct: 759 LYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
F L SLR L L N+++++P A + LS LSHL
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 854
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/220 (21%), Positives = 83/220 (37%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + LDLN N I + + F L LR L L +N ++ I A L L L L+
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLN-RN 113
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF ++++ + ++ N ++ + F
Sbjct: 114 HLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN-QISCIEDGAFR 172
Query: 333 GNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + L + F + +L+ + N C+C L WL D
Sbjct: 173 ALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL----SDWLRQRP 228
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+ G ++ C GP L+G ++ + EF CS
Sbjct: 229 RVGLYTQ----------CMGPSHLRGHNVAEVQKREFVCS 258
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/111 (28%), Positives = 52/111 (46%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L L +++FSNN++ E FE S + + L +N + ++ + L+ L L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I V L ++ L L +N I +V F +L SL L+L N
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 44.8 bits (101), Expect = 8e-04
Identities = 25/71 (35%), Positives = 37/71 (52%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + Q+F +++ L L S NRL P TF+ L SL++LSL N I +P +
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 848
Query: 189 IHLEYLDLSEN 199
L +L + N
Sbjct: 849 SALSHLAIGAN 859
Score = 44.8 bits (101), Expect = 8e-04
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 301 IDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR 359
+ +++F + L + ++ N ++R +PPR F G L + + N + + F +
Sbjct: 792 LSNQSFSNMTQLLTLILSYN-RLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 360 LQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLK 416
L L I NP C+C++ WL S+++K +Y++ +C+GP ++
Sbjct: 851 LSHLAIGANPLYCDCNMQWL-----------------SDWVKSEYKEPGIARCAGPGEMA 893
Query: 417 GMLFVQIPESEFGC 430
L + P +F C
Sbjct: 894 DKLLLTTPSKKFTC 907
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 18/200 (9%)
Query: 235 SLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
+LP ++ + L N + +IP A S L + LS
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
E + F +LQ + +N N K+ + F L + + +N L+T+
Sbjct: 357 GNKITE-LPKSLFEGLFSLQLLLLNAN-KINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 354 HF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGP 412
F P+ +Q + ++ NPF C+C L WL D T I+ +C+ P
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWL----ADYLHTN----------PIETSGARCTSP 460
Query: 413 LQLKGMLFVQIPESEFGCSS 432
+L QI +F CS+
Sbjct: 461 RRLANKRIGQIKSKKFRCSA 480
Score = 41.5 bits (93), Expect = 0.008
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 2/128 (1%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLI 201
+ + N + P F P L+ + L NN I ++ P A G + L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG-LRSLNSLVLYGNKI 360
Query: 202 QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLS 261
++ + L L+ L LN N I + F L +L L L DN + I S L
Sbjct: 361 TELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLR 420
Query: 262 NLSHLYLS 269
+ ++L+
Sbjct: 421 AIQTMHLA 428
Score = 40.7 bits (91), Expect = 0.013
Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 33/218 (15%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDNNMTLI 252
+D S + ++ H + EL+ LNNN ++ G F LP LR ++ S+N +T I
Sbjct: 517 VDCSNQKLNKIPEHIPQYTAELR---LNNNEFTVLEATGIFKKLPQLRKINFSNNKITDI 573
Query: 253 PTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINL 312
A S ++ + L+ E + + F +L
Sbjct: 574 EEGAFEGASGVNEILLT-------------------------SNRLENVQHKMFKGLESL 608
Query: 313 QKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFA 371
+ + + N ++ V F G + + + +N + T+ F + L L + NPF
Sbjct: 609 KTLMLRSN-RITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFN 667
Query: 372 CNCSLLWLWK-LGKDSETTTKKSGNSSEFLK-IDYEDV 407
CNC L WL + L K T FLK I +DV
Sbjct: 668 CNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDV 705
Score = 40.3 bits (90), Expect = 0.018
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L N I + AF +L L ++ N + F +++ L+LS N ++ +
Sbjct: 83 VLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAI 142
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+ AF G +IS I FR L LE L +NN + +F + L+
Sbjct: 143 PRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
Query: 169 ILSLRNNSI 177
L +N++
Sbjct: 203 TFRLHSNNL 211
Score = 38.7 bits (86), Expect = 0.054
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+I++I F S + + ++NRL + + F+ L SLK L LR+N I + + +
Sbjct: 569 KITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIG 628
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
+ + L L +N I V+ L L L+L N
Sbjct: 629 LSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 33.5 bits (73), Expect = 2.0
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
K L +DL+NN I ++ F ++ L L LS N + IP L +L L L G
Sbjct: 777 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHG 834
>AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein.
Length = 709
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 1/209 (0%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
NL ++ + +T + + +N I L + F++ +++ L L NN + + AF G
Sbjct: 117 NLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSL 176
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I+ + F DL LE L +N L P TF L+SL +L L NN +
Sbjct: 177 TKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTR 236
Query: 180 IPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPS 238
+P L + L +LDL N I + L L + N I +++ F L
Sbjct: 237 LPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQK 296
Query: 239 LRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
L L ++ I L NLSH+Y
Sbjct: 297 LDEFSLEGIEISNIQQRMFRPLMNLSHIY 325
Score = 45.2 bits (102), Expect = 6e-04
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 1/133 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F++ L++L NN++ + F L+SL L L +N I + + LE+L +
Sbjct: 146 FKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLII 205
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESV-DQLGFHSLPSLRHLDLSDNNMTLIPTS 255
+N + ++S L L L L NN++ + D+ +P L LDL N++ +
Sbjct: 206 EDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNL 265
Query: 256 ALSKLSNLSHLYL 268
SNL+ L +
Sbjct: 266 TFISCSNLTVLVM 278
Score = 38.3 bits (85), Expect = 0.071
Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Query: 156 FEPETFEPL-SSLKILSLRNNSILDIPSANLGFV----IHLEYLDLSENLIQQVSRHGLP 210
FE ET E L S+ + L LD NL V ++ + L NLI+++
Sbjct: 88 FEAETPECLVGSVPVQCLCQGLELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFK 147
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L+ L L NN I S+ F L SL L LS N +T + L L L +
Sbjct: 148 NYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLII 205
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/133 (34%), Positives = 68/133 (51%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L LE L S N L + F L SLKIL L+NN + IP+ L + L+ L L
Sbjct: 12 FHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRL 71
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
NLI V L L+HL L++N + + ++LP+L+ + L+ N ++ IP A
Sbjct: 72 DANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYA 131
Query: 257 LSKLSNLSHLYLS 269
L++L L L+
Sbjct: 132 FQNLTSLVVLDLN 144
Score = 62.5 bits (145), Expect = 4e-09
Identities = 41/119 (34%), Positives = 56/119 (47%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
N L +P F L L+ L L N + IP + L+ L L N + + L
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L L+ N+I V + F L SLRHL L DN +T IP AL+ L L + L+
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLA 120
Score = 57.2 bits (132), Expect = 1e-07
Identities = 46/168 (27%), Positives = 76/168 (45%), Gaps = 3/168 (1%)
Query: 79 NKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFR 138
N + +L F + L LS N L + AF G ++ I +
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 139 DLSALERLDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
+L +L+ L N L++ PE +FE LSSL+ L L +N++ +IP L + L+ + L+
Sbjct: 62 ELPSLQSLRLDAN-LISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLA 120
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLS 245
N I + + L L LDLN N ++ + +L L+ L L+
Sbjct: 121 LNRISHIPDYAFQNLTSLVVLDLNYNKLQEF-PVAIRTLGRLQELSLN 167
Score = 56.0 bits (129), Expect = 3e-07
Identities = 44/142 (30%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S+I Q F L +L+ L NN+L E L SL+ L L N I +P + +
Sbjct: 28 LSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGL 87
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L +L L +N + ++ L L L+ + L N I + F +L SL LDL+ N
Sbjct: 88 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNK 147
Query: 249 MTLIPTSALSKLSNLSHLYLSG 270
+ P A+ L L L L+G
Sbjct: 148 LQEFPV-AIRTLGRLQELSLNG 168
Score = 49.2 bits (112), Expect = 4e-05
Identities = 48/162 (29%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Query: 71 LTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEIS 130
L L + N I + +FE S +RHL L +N L + A IS
Sbjct: 66 LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRIS 125
Query: 131 NIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPS-ANLGFVI 189
+I F++L++L LD + N+L F P L L+ LSL N +DI +L
Sbjct: 126 HIPDYAFQNLTSLVVLDLNYNKLQEF-PVAIRTLGRLQELSL--NGAMDIQEFPDLKGTT 182
Query: 190 HLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQL 231
LE L L+ I+ + L L+ L+L++N IE + L
Sbjct: 183 SLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSL 224
Score = 32.3 bits (70), Expect = 4.7
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 3/51 (5%)
Query: 34 NANLEIVPIQLN--PEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
NA EI LN P M L N I ++ YAF T L VLD++YNK+
Sbjct: 98 NALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKL 148
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
Query: 88 NFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLD 147
N N+E L+L+ N + R+ K F G +IS I F+DL LERL
Sbjct: 52 NIPRNTE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLR 109
Query: 148 FSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRH 207
+ N L F F + L L L N I IP + ++ L L N I +
Sbjct: 110 LNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDG 169
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L++L+ L LNNN I + F+ +P LR L NN+
Sbjct: 170 AFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I + AF+ Y +L +D
Sbjct: 277 CPAACTCSNNI--VDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRID 334
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I +L + F+ + L L N + L K F G +I+ + V
Sbjct: 335 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 394
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N+L T TF PL +++ + L N +
Sbjct: 395 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFI 437
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N L+++P + + T + L N + + Y LT++D+
Sbjct: 723 CPTECTCLDTV--VRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDL 780
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S N+I L +++F + +++ L LS N L+ + F G +IS +
Sbjct: 781 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 840
Query: 137 FRDLSALERLDFSNNRL 153
F DLSAL L N L
Sbjct: 841 FNDLSALSHLAIGANPL 857
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 3/188 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQL 71
A CP +C C + C L VP + ++L N I + F L
Sbjct: 24 APQACPAQCSCSGS--TVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
VL + NKI + F+ E+ L L+ N L+ + F+G +I
Sbjct: 82 RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQA 141
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I + FR ++ L N++ E F L L++L+L NN+I + A+ + L
Sbjct: 142 IPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKL 201
Query: 192 EYLDLSEN 199
L N
Sbjct: 202 RTFRLHSN 209
Score = 60.9 bits (141), Expect = 1e-08
Identities = 40/135 (29%), Positives = 62/135 (45%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L N++ T E F+ L L+ L L N + P
Sbjct: 67 ITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGT 126
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R ++K+L L+ N I ++ F +L L L L++NN
Sbjct: 127 AKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNN 186
Query: 249 MTLIPTSALSKLSNL 263
+T + ++ + + L
Sbjct: 187 ITRLSVASFNHMPKL 201
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/99 (34%), Positives = 47/99 (47%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + HL L L EN I + R LKEL+ L LN N ++
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F L LDLS+N + IP A ++ +L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQL 158
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 24/187 (12%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLT 72
A CP +C C+ C+N L +P + + L +N + T
Sbjct: 498 ADLACPEKCRCEGT--TVDCSNQKLNKIPEHIPQYTAELRLNNN-------------EFT 542
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
VL+ + F+ ++R +N SNN + +++ AF G + N+
Sbjct: 543 VLE---------ATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 593
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F+ L +L+ L +NR+ ++F LSS+++LSL +N I + + L
Sbjct: 594 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 653
Query: 193 YLDLSEN 199
L+L N
Sbjct: 654 TLNLLAN 660
Score = 51.6 bits (118), Expect = 7e-06
Identities = 32/134 (23%), Positives = 61/134 (45%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + L DAF G
Sbjct: 301 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 360
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + F L +L+ L + N++ + F+ L +L +LSL +N + I
Sbjct: 361 GNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 420
Query: 186 GFVIHLEYLDLSEN 199
+ ++ + L++N
Sbjct: 421 SPLRAIQTMHLAQN 434
Score = 50.8 bits (116), Expect = 1e-05
Identities = 31/111 (27%), Positives = 54/111 (48%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L R+D SNN++ P+ F+ L SL L L N I ++P + + L+ L L
Sbjct: 324 FSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLL 383
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ N I + L L L L +N ++++ + F L +++ + L+ N
Sbjct: 384 NANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 434
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L HL +DLS N I +S + +L L L+ N + +
Sbjct: 755 LYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 813
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
F L SLR L L N+++++P A + LS LSHL
Sbjct: 814 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 850
Score = 46.4 bits (105), Expect = 3e-04
Identities = 47/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + LDLN N I + + F L LR L L +N ++ I A L L L L+
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLN-RN 113
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF ++++ + ++ N ++ + F
Sbjct: 114 HLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN-QISCIEDGAFR 172
Query: 333 GNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + L + F + +L+ + N C+C L WL S+ K
Sbjct: 173 ALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL------SDWLRK 226
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+ ++ +C GP L+G ++ + EF CS
Sbjct: 227 RP-------RVGLY-TQCMGPSHLRGHNVAEVQKREFVCS 258
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/111 (28%), Positives = 52/111 (46%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L L +++FSNN++ E FE S + + L +N + ++ + L+ L L
Sbjct: 550 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 609
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I V L ++ L L +N I +V F +L SL L+L N
Sbjct: 610 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 660
Score = 44.8 bits (101), Expect = 8e-04
Identities = 25/71 (35%), Positives = 37/71 (52%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + Q+F +++ L L S NRL P TF+ L SL++LSL N I +P +
Sbjct: 785 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 844
Query: 189 IHLEYLDLSEN 199
L +L + N
Sbjct: 845 SALSHLAIGAN 855
Score = 44.8 bits (101), Expect = 8e-04
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 301 IDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR 359
+ +++F + L + ++ N ++R +PPR F G L + + N + + F +
Sbjct: 788 LSNQSFSNMTQLLTLILSYN-RLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 846
Query: 360 LQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLK 416
L L I NP C+C++ WL S+++K +Y++ +C+GP ++
Sbjct: 847 LSHLAIGANPLYCDCNMQWL-----------------SDWVKSEYKEPGIARCAGPGEMA 889
Query: 417 GMLFVQIPESEFGC 430
L + P +F C
Sbjct: 890 DKLLLTTPSKKFTC 903
Score = 42.7 bits (96), Expect = 0.003
Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 4/147 (2%)
Query: 235 SLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
+LP ++ + L N + +IP A S L + LS
Sbjct: 301 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 360
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
E + F +LQ + +N N K+ + F L + + +N L+T+
Sbjct: 361 GNKITE-LPKSLFEGLFSLQLLLLNAN-KINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 418
Query: 354 HF-PIDRLQELEISGNPFACNCSLLWL 379
F P+ +Q + ++ NPF C+C L WL
Sbjct: 419 TFSPLRAIQTMHLAQNPFICDCHLKWL 445
Score = 41.5 bits (93), Expect = 0.008
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 2/128 (1%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLI 201
+ + N + P F P L+ + L NN I ++ P A G + L L L N I
Sbjct: 306 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG-LRSLNSLVLYGNKI 364
Query: 202 QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLS 261
++ + L L+ L LN N I + F L +L L L DN + I S L
Sbjct: 365 TELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLR 424
Query: 262 NLSHLYLS 269
+ ++L+
Sbjct: 425 AIQTMHLA 432
Score = 40.7 bits (91), Expect = 0.013
Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 33/218 (15%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDNNMTLI 252
+D S + ++ H + EL+ LNNN ++ G F LP LR ++ S+N +T I
Sbjct: 513 VDCSNQKLNKIPEHIPQYTAELR---LNNNEFTVLEATGIFKKLPQLRKINFSNNKITDI 569
Query: 253 PTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINL 312
A S ++ + L+ E + + F +L
Sbjct: 570 EEGAFEGASGVNEILLT-------------------------SNRLENVQHKMFKGLESL 604
Query: 313 QKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFA 371
+ + + N ++ V F G + + + +N + T+ F + L L + NPF
Sbjct: 605 KTLMLRSN-RITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFN 663
Query: 372 CNCSLLWLWK-LGKDSETTTKKSGNSSEFLK-IDYEDV 407
CNC L WL + L K T FLK I +DV
Sbjct: 664 CNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDV 701
Score = 40.3 bits (90), Expect = 0.018
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L N I + AF +L L ++ N + F +++ L+LS N ++ +
Sbjct: 83 VLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAI 142
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+ AF G +IS I FR L LE L +NN + +F + L+
Sbjct: 143 PRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
Query: 169 ILSLRNNSI 177
L +N++
Sbjct: 203 TFRLHSNNL 211
Score = 38.7 bits (86), Expect = 0.054
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+I++I F S + + ++NRL + + F+ L SLK L LR+N I + + +
Sbjct: 565 KITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIG 624
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
+ + L L +N I V+ L L L+L N
Sbjct: 625 LSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 660
Score = 33.5 bits (73), Expect = 2.0
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
K L +DL+NN I ++ F ++ L L LS N + IP L +L L L G
Sbjct: 773 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHG 830
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
Query: 88 NFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLD 147
N N+E L+L+ N + R+ K F G +IS I F+DL LERL
Sbjct: 52 NIPRNTE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLR 109
Query: 148 FSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRH 207
+ N L F F + L L L N I IP + ++ L L N I +
Sbjct: 110 LNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDG 169
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L++L+ L LNNN I + F+ +P LR L NN+
Sbjct: 170 AFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I + AF+ Y +L +D
Sbjct: 273 CPAACTCSNNI--VDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRID 330
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I +L + F+ + L L N + L K F G +I+ + V
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N+L T TF PL +++ + L N +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFI 433
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N L+++P + + T + L N + + Y LT++D+
Sbjct: 719 CPTECTCLDTV--VRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDL 776
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S N+I L +++F + +++ L LS N L+ + F G +IS +
Sbjct: 777 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 836
Query: 137 FRDLSALERLDFSNNRL 153
F DLSAL L N L
Sbjct: 837 FNDLSALSHLAIGANPL 853
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 3/188 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQL 71
A CP +C C + C L VP + ++L N I + F L
Sbjct: 24 APQACPAQCSCSGS--TVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
VL + NKI + F+ E+ L L+ N L+ + F+G +I
Sbjct: 82 RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQA 141
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I + FR ++ L N++ E F L L++L+L NN+I + A+ + L
Sbjct: 142 IPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKL 201
Query: 192 EYLDLSEN 199
L N
Sbjct: 202 RTFRLHSN 209
Score = 60.9 bits (141), Expect = 1e-08
Identities = 40/135 (29%), Positives = 62/135 (45%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L N++ T E F+ L L+ L L N + P
Sbjct: 67 ITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGT 126
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R ++K+L L+ N I ++ F +L L L L++NN
Sbjct: 127 AKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNN 186
Query: 249 MTLIPTSALSKLSNL 263
+T + ++ + + L
Sbjct: 187 ITRLSVASFNHMPKL 201
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/99 (34%), Positives = 47/99 (47%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + HL L L EN I + R LKEL+ L LN N ++
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F L LDLS+N + IP A ++ +L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQL 158
Score = 51.6 bits (118), Expect = 7e-06
Identities = 32/134 (23%), Positives = 61/134 (45%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + L DAF G
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + F L +L+ L + N++ + F+ L +L +LSL +N + I
Sbjct: 357 GNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Query: 186 GFVIHLEYLDLSEN 199
+ ++ + L++N
Sbjct: 417 SPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 31/111 (27%), Positives = 54/111 (48%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L R+D SNN++ P+ F+ L SL L L N I ++P + + L+ L L
Sbjct: 320 FSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLL 379
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ N I + L L L L +N ++++ + F L +++ + L+ N
Sbjct: 380 NANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L HL +DLS N I +S + +L L L+ N + +
Sbjct: 751 LYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 809
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
F L SLR L L N+++++P A + LS LSHL
Sbjct: 810 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 846
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/187 (22%), Positives = 76/187 (40%), Gaps = 24/187 (12%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLT 72
A CP +C C+ C+N L +P + + L +N + T
Sbjct: 494 ADLACPEKCRCEGT--TVDCSNQKLNKIPEHIPQYTAELRLNNN-------------EFT 538
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
VL+ + F+ ++R +N SNN + +++ AF G + N+
Sbjct: 539 VLE---------ATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 589
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F+ L + L +NR+ ++F LSS+++LSL +N I + + L
Sbjct: 590 QHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLS 649
Query: 193 YLDLSEN 199
L+L N
Sbjct: 650 TLNLLAN 656
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/220 (21%), Positives = 83/220 (37%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + LDLN N I + + F L LR L L +N ++ I A L L L L+
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLN-RN 113
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF ++++ + ++ N ++ + F
Sbjct: 114 HLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN-QISCIEDGAFR 172
Query: 333 GNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + L + F + +L+ + N C+C L WL D
Sbjct: 173 ALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL----SDWLRQRP 228
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+ G ++ C GP L+G ++ + EF CS
Sbjct: 229 RVGLYTQ----------CMGPSHLRGHNVAEVQKREFVCS 258
Score = 44.8 bits (101), Expect = 8e-04
Identities = 25/71 (35%), Positives = 37/71 (52%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + Q+F +++ L L S NRL P TF+ L SL++LSL N I +P +
Sbjct: 781 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 840
Query: 189 IHLEYLDLSEN 199
L +L + N
Sbjct: 841 SALSHLAIGAN 851
Score = 44.8 bits (101), Expect = 8e-04
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 301 IDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR 359
+ +++F + L + ++ N ++R +PPR F G L + + N + + F +
Sbjct: 784 LSNQSFSNMTQLLTLILSYN-RLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 842
Query: 360 LQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLK 416
L L I NP C+C++ WL S+++K +Y++ +C+GP ++
Sbjct: 843 LSHLAIGANPLYCDCNMQWL-----------------SDWVKSEYKEPGIARCAGPGEMA 885
Query: 417 GMLFVQIPESEFGC 430
L + P +F C
Sbjct: 886 DKLLLTTPSKKFTC 899
Score = 42.7 bits (96), Expect = 0.003
Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 4/147 (2%)
Query: 235 SLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
+LP ++ + L N + +IP A S L + LS
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
E + F +LQ + +N N K+ + F L + + +N L+T+
Sbjct: 357 GNKITE-LPKSLFEGLFSLQLLLLNAN-KINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 354 HF-PIDRLQELEISGNPFACNCSLLWL 379
F P+ +Q + ++ NPF C+C L WL
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWL 441
Score = 41.5 bits (93), Expect = 0.008
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 2/128 (1%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLI 201
+ + N + P F P L+ + L NN I ++ P A G + L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG-LRSLNSLVLYGNKI 360
Query: 202 QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLS 261
++ + L L+ L LN N I + F L +L L L DN + I S L
Sbjct: 361 TELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLR 420
Query: 262 NLSHLYLS 269
+ ++L+
Sbjct: 421 AIQTMHLA 428
Score = 40.3 bits (90), Expect = 0.018
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L N I + AF +L L ++ N + F +++ L+LS N ++ +
Sbjct: 83 VLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAI 142
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+ AF G +IS I FR L LE L +NN + +F + L+
Sbjct: 143 PRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
Query: 169 ILSLRNNSI 177
L +N++
Sbjct: 203 TFRLHSNNL 211
Score = 39.9 bits (89), Expect = 0.023
Identities = 52/218 (23%), Positives = 84/218 (38%), Gaps = 33/218 (15%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDNNMTLI 252
+D S + ++ H + EL+ LNNN ++ G F LP LR ++ S+N +T I
Sbjct: 509 VDCSNQKLNKIPEHIPQYTAELR---LNNNEFTVLEATGIFKKLPQLRKINFSNNKITDI 565
Query: 253 PTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINL 312
A S ++ + L+ E + + F
Sbjct: 566 EEGAFEGASGVNEILLT-------------------------SNRLENVQHKMFKGLEKP 600
Query: 313 QKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFA 371
Q + + N ++ V F G + + + +N + T+ F + L L + NPF
Sbjct: 601 QNLMLRSN-RITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFN 659
Query: 372 CNCSLLWLWK-LGKDSETTTKKSGNSSEFLK-IDYEDV 407
CNC L WL + L K T FLK I +DV
Sbjct: 660 CNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDV 697
Score = 33.5 bits (73), Expect = 2.0
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
K L +DL+NN I ++ F ++ L L LS N + IP L +L L L G
Sbjct: 769 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHG 826
Score = 31.9 bits (69), Expect = 6.2
Identities = 24/96 (25%), Positives = 44/96 (45%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+I++I F S + + ++NRL + + F+ L + L LR+N I + + +
Sbjct: 561 KITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIG 620
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
+ + L L +N I V+ L L L+L N
Sbjct: 621 LSSVRMLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 656
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 70.9 bits (166), Expect = 1e-11
Identities = 50/162 (30%), Positives = 70/162 (43%), Gaps = 2/162 (1%)
Query: 88 NFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLD 147
N N+E L+L+ N + R+ K F G +IS I F+DL LERL
Sbjct: 52 NIPRNTE--RLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLR 109
Query: 148 FSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRH 207
+ N L F F + L L L N I IP + ++ L L N I +
Sbjct: 110 LNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDG 169
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L++L+ L LNNN I + F+ +P LR L NN+
Sbjct: 170 AFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNL 211
Score = 70.9 bits (166), Expect = 1e-11
Identities = 45/163 (27%), Positives = 71/163 (43%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I + AF+ Y +L +D
Sbjct: 273 CPAACTCSNNI--VDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRID 330
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I +L + F+ + L L N + L K F G +I+ + V
Sbjct: 331 LSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVD 390
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N+L T TF PL +++ + L N +
Sbjct: 391 AFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFI 433
Score = 62.9 bits (146), Expect = 3e-09
Identities = 39/137 (28%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N L+++P + + T + L N + + Y LT++D+
Sbjct: 727 CPTECTCLDTV--VRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDL 784
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S N+I L +++F + +++ L LS N L+ + F G +IS +
Sbjct: 785 SNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGA 844
Query: 137 FRDLSALERLDFSNNRL 153
F DLSAL L N L
Sbjct: 845 FNDLSALSHLAIGANPL 861
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/188 (24%), Positives = 73/188 (38%), Gaps = 3/188 (1%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQL 71
A CP +C C + C L VP + ++L N I + F L
Sbjct: 24 APQACPAQCSCSGS--TVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHL 81
Query: 72 TVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN 131
VL + NKI + F+ E+ L L+ N L+ + F+G +I
Sbjct: 82 RVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQA 141
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
I + FR ++ L N++ E F L L++L+L NN+I + A+ + L
Sbjct: 142 IPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKL 201
Query: 192 EYLDLSEN 199
L N
Sbjct: 202 RTFRLHSN 209
Score = 60.9 bits (141), Expect = 1e-08
Identities = 40/135 (29%), Positives = 62/135 (45%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L N++ T E F+ L L+ L L N + P
Sbjct: 67 ITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGT 126
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R ++K+L L+ N I ++ F +L L L L++NN
Sbjct: 127 AKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNN 186
Query: 249 MTLIPTSALSKLSNL 263
+T + ++ + + L
Sbjct: 187 ITRLSVASFNHMPKL 201
Score = 56.4 bits (130), Expect = 3e-07
Identities = 34/99 (34%), Positives = 47/99 (47%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + HL L L EN I + R LKEL+ L LN N ++
Sbjct: 60 LDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFP 119
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F L LDLS+N + IP A ++ +L L
Sbjct: 120 ELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQL 158
Score = 53.6 bits (123), Expect = 2e-06
Identities = 43/187 (22%), Positives = 78/187 (41%), Gaps = 24/187 (12%)
Query: 13 AKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLT 72
A CP +C C+ C+N L +P + + L +N + T
Sbjct: 502 ADLACPEKCRCEGT--TVDCSNQKLNKIPEHIPQYTAELRLNNN-------------EFT 546
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
VL+ + F+ ++R +N SNN + +++ AF G + N+
Sbjct: 547 VLE---------ATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENV 597
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F+ L +L+ L +NR+ ++F LSS+++LSL +N I + + L
Sbjct: 598 QHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLS 657
Query: 193 YLDLSEN 199
L+L N
Sbjct: 658 TLNLLAN 664
Score = 51.6 bits (118), Expect = 7e-06
Identities = 32/134 (23%), Positives = 61/134 (45%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + L DAF G
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ + F L +L+ L + N++ + F+ L +L +LSL +N + I
Sbjct: 357 GNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTF 416
Query: 186 GFVIHLEYLDLSEN 199
+ ++ + L++N
Sbjct: 417 SPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 31/111 (27%), Positives = 54/111 (48%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F L R+D SNN++ P+ F+ L SL L L N I ++P + + L+ L L
Sbjct: 320 FSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLL 379
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ N I + L L L L +N ++++ + F L +++ + L+ N
Sbjct: 380 NANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 430
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L HL +DLS N I +S + +L L L+ N + +
Sbjct: 759 LYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIP 817
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
F L SLR L L N+++++P A + LS LSHL
Sbjct: 818 PRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHL 854
Score = 46.0 bits (104), Expect = 4e-04
Identities = 47/220 (21%), Positives = 83/220 (37%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + LDLN N I + + F L LR L L +N ++ I A L L L L+
Sbjct: 55 RNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLN-RN 113
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF ++++ + ++ N ++ + F
Sbjct: 114 HLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYN-QISCIEDGAFR 172
Query: 333 GNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + L + F + +L+ + N C+C L WL D
Sbjct: 173 ALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWL----SDWLRQRP 228
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+ G ++ C GP L+G ++ + EF CS
Sbjct: 229 RVGLYTQ----------CMGPSHLRGHNVAEVQKREFVCS 258
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/111 (28%), Positives = 52/111 (46%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L L +++FSNN++ E FE S + + L +N + ++ + L+ L L
Sbjct: 554 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLML 613
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I V L ++ L L +N I +V F +L SL L+L N
Sbjct: 614 RSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 44.8 bits (101), Expect = 8e-04
Identities = 25/71 (35%), Positives = 37/71 (52%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
IS + Q+F +++ L L S NRL P TF+ L SL++LSL N I +P +
Sbjct: 789 ISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDL 848
Query: 189 IHLEYLDLSEN 199
L +L + N
Sbjct: 849 SALSHLAIGAN 859
Score = 44.8 bits (101), Expect = 8e-04
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 301 IDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDR 359
+ +++F + L + ++ N ++R +PPR F G L + + N + + F +
Sbjct: 792 LSNQSFSNMTQLLTLILSYN-RLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSA 850
Query: 360 LQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLK 416
L L I NP C+C++ WL S+++K +Y++ +C+GP ++
Sbjct: 851 LSHLAIGANPLYCDCNMQWL-----------------SDWVKSEYKEPGIARCAGPGEMA 893
Query: 417 GMLFVQIPESEFGC 430
L + P +F C
Sbjct: 894 DKLLLTTPSKKFTC 907
Score = 43.2 bits (97), Expect = 0.003
Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 18/200 (9%)
Query: 235 SLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXX 293
+LP ++ + L N + +IP A S L + LS
Sbjct: 297 NLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLY 356
Query: 294 XXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEAS 353
E + F +LQ + +N N K+ + F L + + +N L+T+
Sbjct: 357 GNKITE-LPKSLFEGLFSLQLLLLNAN-KINCLRVDAFQDLHNLNLLSLYDNKLQTIAKG 414
Query: 354 HF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGP 412
F P+ +Q + ++ NPF C+C L WL D T I+ +C+ P
Sbjct: 415 TFSPLRAIQTMHLAQNPFICDCHLKWL----ADYLHTN----------PIETSGARCTSP 460
Query: 413 LQLKGMLFVQIPESEFGCSS 432
+L QI +F CS+
Sbjct: 461 RRLANKRIGQIKSKKFRCSA 480
Score = 41.5 bits (93), Expect = 0.008
Identities = 35/128 (27%), Positives = 54/128 (42%), Gaps = 2/128 (1%)
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLI 201
+ + N + P F P L+ + L NN I ++ P A G + L L L N I
Sbjct: 302 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQG-LRSLNSLVLYGNKI 360
Query: 202 QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLS 261
++ + L L+ L LN N I + F L +L L L DN + I S L
Sbjct: 361 TELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLR 420
Query: 262 NLSHLYLS 269
+ ++L+
Sbjct: 421 AIQTMHLA 428
Score = 40.7 bits (91), Expect = 0.013
Identities = 52/218 (23%), Positives = 86/218 (39%), Gaps = 33/218 (15%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDNNMTLI 252
+D S + ++ H + EL+ LNNN ++ G F LP LR ++ S+N +T I
Sbjct: 517 VDCSNQKLNKIPEHIPQYTAELR---LNNNEFTVLEATGIFKKLPQLRKINFSNNKITDI 573
Query: 253 PTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINL 312
A S ++ + L+ E + + F +L
Sbjct: 574 EEGAFEGASGVNEILLT-------------------------SNRLENVQHKMFKGLESL 608
Query: 313 QKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFA 371
+ + + N ++ V F G + + + +N + T+ F + L L + NPF
Sbjct: 609 KTLMLRSN-RITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFN 667
Query: 372 CNCSLLWLWK-LGKDSETTTKKSGNSSEFLK-IDYEDV 407
CNC L WL + L K T FLK I +DV
Sbjct: 668 CNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDV 705
Score = 40.3 bits (90), Expect = 0.018
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 1/129 (0%)
Query: 50 LMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
++ L N I + AF +L L ++ N + F +++ L+LS N ++ +
Sbjct: 83 VLQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAI 142
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+ AF G +IS I FR L LE L +NN + +F + L+
Sbjct: 143 PRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLR 202
Query: 169 ILSLRNNSI 177
L +N++
Sbjct: 203 TFRLHSNNL 211
Score = 38.7 bits (86), Expect = 0.054
Identities = 27/96 (28%), Positives = 46/96 (47%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
+I++I F S + + ++NRL + + F+ L SLK L LR+N I + + +
Sbjct: 569 KITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIG 628
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
+ + L L +N I V+ L L L+L N
Sbjct: 629 LSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLAN 664
Score = 33.5 bits (73), Expect = 2.0
Identities = 20/58 (34%), Positives = 28/58 (48%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
K L +DL+NN I ++ F ++ L L LS N + IP L +L L L G
Sbjct: 777 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHG 834
>Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen
protein.
Length = 420
Score = 70.5 bits (165), Expect = 1e-11
Identities = 66/237 (27%), Positives = 100/237 (42%), Gaps = 9/237 (3%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL---YTQLT 72
CP C C +A R C N NL VP L + LT N + L AF +L
Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
L++S +++ ++ + FE +R L+LS+N L L AF G E+
Sbjct: 122 ALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILN 181
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
H+ D ER + S +V L L+ L L +N L +P L + L
Sbjct: 182 HIVPPED----ERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLR 237
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL-SDNN 248
+LDLS N + ++ L L+ L L +N ++ + L L H+ + DNN
Sbjct: 238 HLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNN 294
Score = 39.9 bits (89), Expect = 0.023
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 23/185 (12%)
Query: 95 MRHLNLSNNFLKRLDKDAFVGX---XXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
+R+L L+ N L L AF + + F L +L +LD S+N
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
L P F +N+ + PS + + L ++ E+ Q S G+
Sbjct: 153 PLADLSPFAFSG----------SNASVSAPSPLVELI--LNHIVPPEDERQNRSFEGMVV 200
Query: 212 --------LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L+ L+L +N + + LPSLRHLDLS+N++ + + L++L
Sbjct: 201 AALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHL 260
Query: 264 SHLYL 268
L+L
Sbjct: 261 ESLHL 265
>CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein.
Length = 473
Score = 70.5 bits (165), Expect = 1e-11
Identities = 70/270 (25%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 2 VLFAWTWSAAAAKTLCPVRCMC-DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
VL+ W AA CP C+C ++ SC L+ VP+ + P A+ H
Sbjct: 15 VLWLQAWQVAAP---CPGACVCYNEPKVTTSCPQQGLQAVPVGI-PAASQRIFLHG---- 66
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
N+I + + +F + + L L +N L R+D AF G
Sbjct: 67 ------------------NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLE 108
Query: 121 XXXXXX-XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
++ ++ TF L L L L P F L++L+ L L++N++
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P + +L +L L N I V L L L L+ N + V F L L
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L NN++ +PT AL+ L L +L L+
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 69.3 bits (162), Expect = 3e-11
Identities = 67/247 (27%), Positives = 105/247 (42%), Gaps = 36/247 (14%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+A +R+ NR+ +F +L IL L +N + I +A + LE LDLS+N
Sbjct: 57 AASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA 116
Query: 201 ----IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
+ + HGL L L HLD ++ + F L +L++L L DN + +P
Sbjct: 117 QLRSVDPATFHGLGRLHTL-HLDRCG--LQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L NL+HL+L G + RAF +L ++
Sbjct: 174 FRDLGNLTHLFLHGNRISS-------------------------VPERAFRGLHSLDRLL 208
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCS 375
++ N +V V P F +L +Y+ N L L P+ LQ L ++ NP+ C+C
Sbjct: 209 LHQN-RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCR 267
Query: 376 L--LWLW 380
LW W
Sbjct: 268 ARPLWAW 274
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L L + + +LG F + +++L L +N L+ L D F I
Sbjct: 131 RLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRI 190
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
S++ + FR L +L+RL NR+ P F L L L L N++ +P+ L +
Sbjct: 191 SSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLR 250
Query: 190 HLEYLDLSEN 199
L+YL L++N
Sbjct: 251 ALQYLRLNDN 260
Score = 33.9 bits (74), Expect = 1.5
Identities = 31/151 (20%), Positives = 57/151 (37%), Gaps = 7/151 (4%)
Query: 224 IIESVDQLGFHSLP-----SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
+ S Q G ++P + + + L N ++ +P ++ NL+ L+L
Sbjct: 39 VTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDA 98
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+D F L + + D ++E+ P LF G L
Sbjct: 99 AAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL-DRCGLQELGPGLFRGLAALQ 157
Query: 339 NIYMKNNALETLEASHF-PIDRLQELEISGN 368
+Y+++NAL+ L F + L L + GN
Sbjct: 158 YLYLQDNALQALPDDTFRDLGNLTHLFLHGN 188
>BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 7/181 (3%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL--YAFNL 67
A A CP C+C A SC+ L VP L L++L+HN + L +
Sbjct: 27 AGRAVVSCPAACLC--ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTR 84
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
TQL L +S+N + + SE F +R+L+LS+N L+ LD+ F
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFE---PLSSLKILSLRNNSILDIPSAN 184
I + F D++ L++L S N++ F E + L L +L L +N + ++P +
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 185 L 185
L
Sbjct: 205 L 205
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/124 (33%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
LD S+N L E T L+ L L L +N + I S V +L YLDLS N ++ +
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L+ L+ L L NN I +VD+ F + L+ L LS N ++ P + + + L
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLP 185
Query: 265 HLYL 268
L L
Sbjct: 186 KLTL 189
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 98 LNLSNNFLKRLDKD-AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
L+LS+N L RL + ++ I + F + L LD S+N+L T
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE-- 214
+ F L L++L L NN I+ + + L+ L LS+N Q+SR L +KE
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQN---QISRFPLELVKEGA 182
Query: 215 ----LKHLDLNNNIIESVDQLGFHSLPS 238
L LDL++N ++++ LP+
Sbjct: 183 KLPKLTLLDLSSNKLKNLPLPDLQKLPA 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
Query: 140 LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L L S+N L E F P+ +L+ L L +N + + + LE L L N
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNIIESVD-QLGFHS--LPSLRHLDLSDNNMTLIPTSA 256
I V R + +L+ L L+ N I +L LP L LDLS N + +P
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 257 LSKL 260
L KL
Sbjct: 205 LQKL 208
>BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotein
protein.
Length = 420
Score = 70.5 bits (165), Expect = 1e-11
Identities = 66/237 (27%), Positives = 100/237 (42%), Gaps = 9/237 (3%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL---YTQLT 72
CP C C +A R C N NL VP L + LT N + L AF +L
Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
L++S +++ ++ + FE +R L+LS+N L L AF G E+
Sbjct: 122 ALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILN 181
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
H+ D ER + S +V L L+ L L +N L +P L + L
Sbjct: 182 HIVPPED----ERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLR 237
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL-SDNN 248
+LDLS N + ++ L L+ L L +N ++ + L L H+ + DNN
Sbjct: 238 HLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNN 294
Score = 39.9 bits (89), Expect = 0.023
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 23/185 (12%)
Query: 95 MRHLNLSNNFLKRLDKDAFVGX---XXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
+R+L L+ N L L AF + + F L +L +LD S+N
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
L P F +N+ + PS + + L ++ E+ Q S G+
Sbjct: 153 PLADLSPFAFSG----------SNASVSAPSPLVELI--LNHIVPPEDERQNRSFEGMVV 200
Query: 212 --------LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L+ L+L +N + + LPSLRHLDLS+N++ + + L++L
Sbjct: 201 AALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHL 260
Query: 264 SHLYL 268
L+L
Sbjct: 261 ESLHL 265
>BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor
protein.
Length = 473
Score = 70.5 bits (165), Expect = 1e-11
Identities = 70/270 (25%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 2 VLFAWTWSAAAAKTLCPVRCMC-DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
VL+ W AA CP C+C ++ SC L+ VP+ + P A+ H
Sbjct: 15 VLWLQAWQVAAP---CPGACVCYNEPKVTTSCPQQGLQAVPVGI-PAASQRIFLHG---- 66
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
N+I + + +F + + L L +N L R+D AF G
Sbjct: 67 ------------------NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLE 108
Query: 121 XXXXXX-XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
++ ++ TF L L L L P F L++L+ L L++N++
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P + +L +L L N I V L L L L+ N + V F L L
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L NN++ +PT AL+ L L +L L+
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 69.3 bits (162), Expect = 3e-11
Identities = 67/247 (27%), Positives = 105/247 (42%), Gaps = 36/247 (14%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+A +R+ NR+ +F +L IL L +N + I +A + LE LDLS+N
Sbjct: 57 AASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA 116
Query: 201 ----IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
+ + HGL L L HLD ++ + F L +L++L L DN + +P
Sbjct: 117 QLRSVDPATFHGLGRLHTL-HLDRCG--LQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L NL+HL+L G + RAF +L ++
Sbjct: 174 FRDLGNLTHLFLHGNRISS-------------------------VPERAFRGLHSLDRLL 208
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCS 375
++ N +V V P F +L +Y+ N L L P+ LQ L ++ NP+ C+C
Sbjct: 209 LHQN-RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCR 267
Query: 376 L--LWLW 380
LW W
Sbjct: 268 ARPLWAW 274
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L L + + +LG F + +++L L +N L+ L D F I
Sbjct: 131 RLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRI 190
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
S++ + FR L +L+RL NR+ P F L L L L N++ +P+ L +
Sbjct: 191 SSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLR 250
Query: 190 HLEYLDLSEN 199
L+YL L++N
Sbjct: 251 ALQYLRLNDN 260
Score = 33.9 bits (74), Expect = 1.5
Identities = 31/151 (20%), Positives = 57/151 (37%), Gaps = 7/151 (4%)
Query: 224 IIESVDQLGFHSLP-----SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
+ S Q G ++P + + + L N ++ +P ++ NL+ L+L
Sbjct: 39 VTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDA 98
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+D F L + + D ++E+ P LF G L
Sbjct: 99 AAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL-DRCGLQELGPGLFRGLAALQ 157
Query: 339 NIYMKNNALETLEASHF-PIDRLQELEISGN 368
+Y+++NAL+ L F + L L + GN
Sbjct: 158 YLYLQDNALQALPDDTFRDLGNLTHLFLHGN 188
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 70.5 bits (165), Expect = 1e-11
Identities = 48/168 (28%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
S A CP C C + + C L +P L + L N+I + AF
Sbjct: 272 SCNANSISCPSPCTCSNNI--VDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQ 329
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Y +L +DIS N+I D+ + F+ + L L N + + K F G
Sbjct: 330 YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNAN 389
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I+ + V TF+DL L L +N+L T F PL S++ L L N
Sbjct: 390 KINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 66.5 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 66/152 (43%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L N + R+ K F G ++S I F+DL LERL + N+L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L L L N I IP + ++ L L N I + L++L+
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L LNNN I + F+ +P +R L L N++
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 64.5 bits (150), Expect = 1e-09
Identities = 41/140 (29%), Positives = 67/140 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L +N++ E F+ L L+ L L N + +P
Sbjct: 73 ITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQST 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R + ++K+L L+NN I ++ F +L L L L++NN
Sbjct: 133 PKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 192
Query: 249 MTLIPTSALSKLSNLSHLYL 268
++ I ++ + + + L L
Sbjct: 193 ISRILVTSFNHMPKIRTLRL 212
Score = 63.3 bits (147), Expect = 2e-09
Identities = 45/182 (24%), Positives = 88/182 (48%), Gaps = 4/182 (2%)
Query: 20 RCMCDDALRAASCANANLEIV-PIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISY 78
RC + R+ + +++V P + E T+++ ++ + + +L +T L ++
Sbjct: 484 RCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRI--PSHLPEYVTDLRLND 541
Query: 79 NKILDLGSEN-FESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTF 137
N++ L + F+ +R +NLSNN +K + + AF G ++ +H + F
Sbjct: 542 NEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVF 601
Query: 138 RDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
R LS L+ L +N + +TF LSS+++LSL +N I I ++ L ++L
Sbjct: 602 RGLSGLKTLMLRSNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLL 661
Query: 198 EN 199
N
Sbjct: 662 SN 663
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLD 75
CP +C C A + C L VP + A ++L N I + F L VL
Sbjct: 34 CPTKCTCSAA--SVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ N++ + F+ ++ L L+ N L+ L + F +I I +
Sbjct: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR ++ ++ L NN + E F L L+IL+L NN+I I + + + L
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211
Query: 196 LSEN 199
L N
Sbjct: 212 LHSN 215
Score = 60.9 bits (141), Expect = 1e-08
Identities = 91/433 (21%), Positives = 164/433 (37%), Gaps = 49/433 (11%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL- 74
+CP +C C+ + C+N L +P L T + L N + ++L A ++ +L L
Sbjct: 504 VCPEKCRCEGTI--VDCSNQKLVRIPSHLPEYVTDLRLNDNEV-SVLEATGIFKKLPNLR 560
Query: 75 --DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
++S NKI ++ F+ + ++ L L+ N L+ + F G IS +
Sbjct: 561 KINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLISCV 620
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF LS++ L +NR+ T P + ++SL ++L P HL
Sbjct: 621 SNDTFAGLSSVRLLSLYDNRIT-----TITPGAFTTLVSLSTINLLSNP---FNCNCHLA 672
Query: 193 YLDL---SENLIQQVSRHGLPF-LKELKHLD--LNNNIIESVDQLGFHSLPSLRHLDLSD 246
+L ++ R PF LKE+ D + + + ++ P
Sbjct: 673 WLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCM 732
Query: 247 NNMTLIPTSALSKL-----SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERI 301
+ L L +++ LYL G +
Sbjct: 733 ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM--L 790
Query: 302 DSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRL 360
+ F + +L + ++ N ++R +P F+G L + + N + ++ E S + L
Sbjct: 791 TNYTFSNMSHLSTLILSYN-RLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 849
Query: 361 QELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKG 417
L + NP C+CSL WL SE++K Y++ +CS P +
Sbjct: 850 SHLALGTNPLHCDCSLRWL-----------------SEWVKAGYKEPGIARCSSPEPMAD 892
Query: 418 MLFVQIPESEFGC 430
L + P F C
Sbjct: 893 RLLLTTPTHRFQC 905
Score = 57.2 bits (132), Expect = 1e-07
Identities = 32/99 (32%), Positives = 52/99 (52%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + +L L L +N + + R LK+L+ L LN N ++ +
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F S P L LDLS+N + IP A ++++ +L L
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL 164
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/217 (23%), Positives = 85/217 (39%), Gaps = 23/217 (10%)
Query: 221 NNNIIESVDQLGFHSLPS-----LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXX 275
+NNI++ + G +P+ + + L N++ IP A ++ L + +S
Sbjct: 287 SNNIVDCRGK-GLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISD 345
Query: 276 XXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNP 335
E I F ++LQ + +N N K+ + F
Sbjct: 346 IAPDAFQGLKSLTSLVLYGNKITE-IAKGLFDGLVSLQLLLLNAN-KINCLRVNTFQDLQ 403
Query: 336 KLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSG 394
L + + +N L+T+ F P+ +Q L ++ NPF C+C L WL +D+ T SG
Sbjct: 404 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIET--SG 461
Query: 395 NSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+CS P +L QI +F CS
Sbjct: 462 ------------ARCSSPRRLANKRISQIKSKKFRCS 486
Score = 46.0 bits (104), Expect = 4e-04
Identities = 30/134 (22%), Positives = 60/134 (44%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + + + N I + + F +++ +++S N + + DAF G
Sbjct: 304 NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLY 363
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ I F L +L+ L + N++ TF+ L +L +LSL +N + I
Sbjct: 364 GNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLF 423
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 424 APLQSIQTLHLAQN 437
Score = 45.6 bits (103), Expect = 5e-04
Identities = 38/173 (21%), Positives = 70/173 (40%), Gaps = 5/173 (2%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P + + LDL+ N I + ++ F L +LR L L DN +++I A L L L
Sbjct: 58 GIP--RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLR 115
Query: 268 LSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVP 327
L+ + I +AF +++ + + DN + +
Sbjct: 116 LN-KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL-DNNHISCIE 173
Query: 328 PRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL 379
F L + + NN + + + F + +++ L + N C+C L WL
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWL 226
Score = 45.6 bits (103), Expect = 5e-04
Identities = 32/114 (28%), Positives = 51/114 (44%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF QL L ++ NK+ L F+S ++ L+LS N ++ + + AF G
Sbjct: 104 AFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
IS I FR L LE L +NN + +F + ++ L L +N +
Sbjct: 164 LDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/99 (30%), Positives = 46/99 (46%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L NSI IP+ L+ +D+S+N I ++ LK L L L N I +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L SL+ L L+ N + + + L NL+ L L
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSL 410
>AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein.
Length = 473
Score = 70.5 bits (165), Expect = 1e-11
Identities = 70/270 (25%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 2 VLFAWTWSAAAAKTLCPVRCMC-DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
VL+ W AA CP C+C ++ SC L+ VP+ + P A+ H
Sbjct: 15 VLWLQAWQVAAP---CPGACVCYNEPKVTTSCPQQGLQAVPVGI-PAASQRIFLHG---- 66
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
N+I + + +F + + L L +N L R+D AF G
Sbjct: 67 ------------------NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLE 108
Query: 121 XXXXXX-XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
++ ++ TF L L L L P F L++L+ L L++N++
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P + +L +L L N I V L L L L+ N + V F L L
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L NN++ +PT AL+ L L +L L+
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 69.3 bits (162), Expect = 3e-11
Identities = 67/247 (27%), Positives = 105/247 (42%), Gaps = 36/247 (14%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+A +R+ NR+ +F +L IL L +N + I +A + LE LDLS+N
Sbjct: 57 AASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA 116
Query: 201 ----IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
+ + HGL L L HLD ++ + F L +L++L L DN + +P
Sbjct: 117 QLRSVDPATFHGLGRLHTL-HLDRCG--LQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L NL+HL+L G + RAF +L ++
Sbjct: 174 FRDLGNLTHLFLHGNRISS-------------------------VPERAFRGLHSLDRLL 208
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCS 375
++ N +V V P F +L +Y+ N L L P+ LQ L ++ NP+ C+C
Sbjct: 209 LHQN-RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCR 267
Query: 376 L--LWLW 380
LW W
Sbjct: 268 ARPLWAW 274
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L L + + +LG F + +++L L +N L+ L D F I
Sbjct: 131 RLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRI 190
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
S++ + FR L +L+RL NR+ P F L L L L N++ +P+ L +
Sbjct: 191 SSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLR 250
Query: 190 HLEYLDLSEN 199
L+YL L++N
Sbjct: 251 ALQYLRLNDN 260
Score = 33.9 bits (74), Expect = 1.5
Identities = 31/151 (20%), Positives = 57/151 (37%), Gaps = 7/151 (4%)
Query: 224 IIESVDQLGFHSLP-----SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
+ S Q G ++P + + + L N ++ +P ++ NL+ L+L
Sbjct: 39 VTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDA 98
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+D F L + + D ++E+ P LF G L
Sbjct: 99 AAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL-DRCGLQELGPGLFRGLAALQ 157
Query: 339 NIYMKNNALETLEASHF-PIDRLQELEISGN 368
+Y+++NAL+ L F + L L + GN
Sbjct: 158 YLYLQDNALQALPDDTFRDLGNLTHLFLHGN 188
>AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein
AMIGO protein.
Length = 493
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 7/181 (3%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL--YAFNL 67
A A CP C+C A SC+ L VP L L++L+HN + L +
Sbjct: 27 AGRAVVSCPAACLC--ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTR 84
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
TQL L +S+N + + SE F +R+L+LS+N L+ LD+ F
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFE---PLSSLKILSLRNNSILDIPSAN 184
I + F D++ L++L S N++ F E + L L +L L +N + ++P +
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 185 L 185
L
Sbjct: 205 L 205
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/124 (33%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
LD S+N L E T L+ L L L +N + I S V +L YLDLS N ++ +
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L+ L+ L L NN I +VD+ F + L+ L LS N ++ P + + + L
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLP 185
Query: 265 HLYL 268
L L
Sbjct: 186 KLTL 189
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 98 LNLSNNFLKRLDKD-AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
L+LS+N L RL + ++ I + F + L LD S+N+L T
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE-- 214
+ F L L++L L NN I+ + + L+ L LS+N Q+SR L +KE
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQN---QISRFPLELVKEGA 182
Query: 215 ----LKHLDLNNNIIESVDQLGFHSLPS 238
L LDL++N ++++ LP+
Sbjct: 183 KLPKLTLLDLSSNKLKNLPLPDLQKLPA 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
Query: 140 LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L L S+N L E F P+ +L+ L L +N + + + LE L L N
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNIIESVD-QLGFHS--LPSLRHLDLSDNNMTLIPTSA 256
I V R + +L+ L L+ N I +L LP L LDLS N + +P
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 257 LSKL 260
L KL
Sbjct: 205 LQKL 208
>AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with
Ig-like domain 1 protein.
Length = 493
Score = 70.5 bits (165), Expect = 1e-11
Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 7/181 (3%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL--YAFNL 67
A A CP C+C A SC+ L VP L L++L+HN + L +
Sbjct: 27 AGRAVVSCPAACLC--ASNILSCSKQQLPNVPHSLPSYTALLDLSHNNLSRLRAEWTPTR 84
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
TQL L +S+N + + SE F +R+L+LS+N L+ LD+ F
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFE---PLSSLKILSLRNNSILDIPSAN 184
I + F D++ L++L S N++ F E + L L +L L +N + ++P +
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 185 L 185
L
Sbjct: 205 L 205
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/124 (33%), Positives = 60/124 (48%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
LD S+N L E T L+ L L L +N + I S V +L YLDLS N ++ +
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L+ L+ L L NN I +VD+ F + L+ L LS N ++ P + + + L
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLP 185
Query: 265 HLYL 268
L L
Sbjct: 186 KLTL 189
Score = 46.8 bits (106), Expect = 2e-04
Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 10/148 (6%)
Query: 98 LNLSNNFLKRLDKD-AFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTF 156
L+LS+N L RL + ++ I + F + L LD S+N+L T
Sbjct: 66 LDLSHNNLSRLRAEWTPTRLTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTL 125
Query: 157 EPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE-- 214
+ F L L++L L NN I+ + + L+ L LS+N Q+SR L +KE
Sbjct: 126 DEFLFSDLQVLEVLLLYNNHIMAVDRCAFDDMAQLQKLYLSQN---QISRFPLELVKEGA 182
Query: 215 ----LKHLDLNNNIIESVDQLGFHSLPS 238
L LDL++N ++++ LP+
Sbjct: 183 KLPKLTLLDLSSNKLKNLPLPDLQKLPA 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 39/124 (31%), Positives = 55/124 (44%), Gaps = 3/124 (2%)
Query: 140 LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L L S+N L E F P+ +L+ L L +N + + + LE L L N
Sbjct: 85 LTQLHSLLLSHNHLNFISSEAFSPVPNLRYLDLSSNQLRTLDEFLFSDLQVLEVLLLYNN 144
Query: 200 LIQQVSRHGLPFLKELKHLDLNNNIIESVD-QLGFHS--LPSLRHLDLSDNNMTLIPTSA 256
I V R + +L+ L L+ N I +L LP L LDLS N + +P
Sbjct: 145 HIMAVDRCAFDDMAQLQKLYLSQNQISRFPLELVKEGAKLPKLTLLDLSSNKLKNLPLPD 204
Query: 257 LSKL 260
L KL
Sbjct: 205 LQKL 208
>AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotein
protein.
Length = 420
Score = 70.5 bits (165), Expect = 1e-11
Identities = 66/237 (27%), Positives = 100/237 (42%), Gaps = 9/237 (3%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL---YTQLT 72
CP C C +A R C N NL VP L + LT N + L AF +L
Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
L++S +++ ++ + FE +R L+LS+N L L AF G E+
Sbjct: 122 ALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILN 181
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
H+ D ER + S +V L L+ L L +N L +P L + L
Sbjct: 182 HIVPPED----ERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLR 237
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL-SDNN 248
+LDLS N + ++ L L+ L L +N ++ + L L H+ + DNN
Sbjct: 238 HLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNN 294
Score = 39.9 bits (89), Expect = 0.023
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 23/185 (12%)
Query: 95 MRHLNLSNNFLKRLDKDAFVGX---XXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
+R+L L+ N L L AF + + F L +L +LD S+N
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
L P F +N+ + PS + + L ++ E+ Q S G+
Sbjct: 153 PLADLSPFAFSG----------SNASVSAPSPLVELI--LNHIVPPEDERQNRSFEGMVV 200
Query: 212 --------LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L+ L+L +N + + LPSLRHLDLS+N++ + + L++L
Sbjct: 201 AALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHL 260
Query: 264 SHLYL 268
L+L
Sbjct: 261 ESLHL 265
>AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophoblast
glycoprotein protein.
Length = 420
Score = 70.5 bits (165), Expect = 1e-11
Identities = 66/237 (27%), Positives = 100/237 (42%), Gaps = 9/237 (3%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL---YTQLT 72
CP C C +A R C N NL VP L + LT N + L AF +L
Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121
Query: 73 VLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
L++S +++ ++ + FE +R L+LS+N L L AF G E+
Sbjct: 122 ALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILN 181
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
H+ D ER + S +V L L+ L L +N L +P L + L
Sbjct: 182 HIVPPED----ERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLR 237
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDL-SDNN 248
+LDLS N + ++ L L+ L L +N ++ + L L H+ + DNN
Sbjct: 238 HLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNN 294
Score = 39.9 bits (89), Expect = 0.023
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 23/185 (12%)
Query: 95 MRHLNLSNNFLKRLDKDAFVGX---XXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNN 151
+R+L L+ N L L AF + + F L +L +LD S+N
Sbjct: 93 VRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHN 152
Query: 152 RLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPF 211
L P F +N+ + PS + + L ++ E+ Q S G+
Sbjct: 153 PLADLSPFAFSG----------SNASVSAPSPLVELI--LNHIVPPEDERQNRSFEGMVV 200
Query: 212 --------LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L+ L+L +N + + LPSLRHLDLS+N++ + + L++L
Sbjct: 201 AALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHL 260
Query: 264 SHLYL 268
L+L
Sbjct: 261 ESLHL 265
>AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein.
Length = 473
Score = 70.5 bits (165), Expect = 1e-11
Identities = 70/270 (25%), Positives = 109/270 (40%), Gaps = 28/270 (10%)
Query: 2 VLFAWTWSAAAAKTLCPVRCMC-DDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
VL+ W AA CP C+C ++ SC L+ VP+ + P A+ H
Sbjct: 15 VLWLQAWQVAAP---CPGACVCYNEPKVTTSCPQQGLQAVPVGI-PAASQRIFLHG---- 66
Query: 61 LLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXX 120
N+I + + +F + + L L +N L R+D AF G
Sbjct: 67 ------------------NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLE 108
Query: 121 XXXXXX-XEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
++ ++ TF L L L L P F L++L+ L L++N++
Sbjct: 109 QLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQA 168
Query: 180 IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSL 239
+P + +L +L L N I V L L L L+ N + V F L L
Sbjct: 169 LPDDTFRDLGNLTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRL 228
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L NN++ +PT AL+ L L +L L+
Sbjct: 229 MTLYLFANNLSALPTEALAPLRALQYLRLN 258
Score = 69.3 bits (162), Expect = 3e-11
Identities = 67/247 (27%), Positives = 105/247 (42%), Gaps = 36/247 (14%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+A +R+ NR+ +F +L IL L +N + I +A + LE LDLS+N
Sbjct: 57 AASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA 116
Query: 201 ----IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSA 256
+ + HGL L L HLD ++ + F L +L++L L DN + +P
Sbjct: 117 QLRSVDPATFHGLGRLHTL-HLDRCG--LQELGPGLFRGLAALQYLYLQDNALQALPDDT 173
Query: 257 LSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIW 316
L NL+HL+L G + RAF +L ++
Sbjct: 174 FRDLGNLTHLFLHGNRISS-------------------------VPERAFRGLHSLDRLL 208
Query: 317 MNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCS 375
++ N +V V P F +L +Y+ N L L P+ LQ L ++ NP+ C+C
Sbjct: 209 LHQN-RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRLNDNPWVCDCR 267
Query: 376 L--LWLW 380
LW W
Sbjct: 268 ARPLWAW 274
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/130 (27%), Positives = 60/130 (46%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEI 129
+L L + + +LG F + +++L L +N L+ L D F I
Sbjct: 131 RLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALPDDTFRDLGNLTHLFLHGNRI 190
Query: 130 SNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVI 189
S++ + FR L +L+RL NR+ P F L L L L N++ +P+ L +
Sbjct: 191 SSVPERAFRGLHSLDRLLLHQNRVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLR 250
Query: 190 HLEYLDLSEN 199
L+YL L++N
Sbjct: 251 ALQYLRLNDN 260
Score = 33.9 bits (74), Expect = 1.5
Identities = 31/151 (20%), Positives = 57/151 (37%), Gaps = 7/151 (4%)
Query: 224 IIESVDQLGFHSLP-----SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXX 278
+ S Q G ++P + + + L N ++ +P ++ NL+ L+L
Sbjct: 39 VTTSCPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDA 98
Query: 279 XXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLT 338
+D F L + + D ++E+ P LF G L
Sbjct: 99 AAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHL-DRCGLQELGPGLFRGLAALQ 157
Query: 339 NIYMKNNALETLEASHF-PIDRLQELEISGN 368
+Y+++NAL+ L F + L L + GN
Sbjct: 158 YLYLQDNALQALPDDTFRDLGNLTHLFLHGN 188
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 70.5 bits (165), Expect = 1e-11
Identities = 48/168 (28%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
S A CP C C + + C L +P L + L N+I + AF
Sbjct: 272 SCNANSISCPSPCTCSNNI--VDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQ 329
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Y +L +DIS N+I D+ + F+ + L L N + + K F G
Sbjct: 330 YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNAN 389
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I+ + V TF+DL L L +N+L T F PL S++ L L N
Sbjct: 390 KINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 437
Score = 66.5 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 66/152 (43%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L N + R+ K F G ++S I F+DL LERL + N+L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L L L N I IP + ++ L L N I + L++L+
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 185
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L LNNN I + F+ +P +R L L N++
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 64.5 bits (150), Expect = 1e-09
Identities = 41/140 (29%), Positives = 67/140 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L +N++ E F+ L L+ L L N + +P
Sbjct: 73 ITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQST 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R + ++K+L L+NN I ++ F +L L L L++NN
Sbjct: 133 PKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 192
Query: 249 MTLIPTSALSKLSNLSHLYL 268
++ I ++ + + + L L
Sbjct: 193 ISRILVTSFNHMPKIRTLRL 212
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/182 (24%), Positives = 88/182 (48%), Gaps = 4/182 (2%)
Query: 20 RCMCDDALRAASCANANLEIV-PIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISY 78
RC + R+ + +++V P + E T+++ ++ + + +L +T L ++
Sbjct: 484 RCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRI--PSHLPEYVTDLRLND 541
Query: 79 NKILDLGSEN-FESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTF 137
N++ L + F+ +R +NLSNN +K + + AF G ++ +H + F
Sbjct: 542 NEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVF 601
Query: 138 RDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
R LS L+ L +N + +TF LSS+++LSL +N I I ++ L ++L
Sbjct: 602 RGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLL 661
Query: 198 EN 199
N
Sbjct: 662 SN 663
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLD 75
CP +C C A + C L VP + A ++L N I + F L VL
Sbjct: 34 CPTKCTCSAA--SVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ N++ + F+ ++ L L+ N L+ L + F +I I +
Sbjct: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR ++ ++ L NN + E F L L+IL+L NN+I I + + + L
Sbjct: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211
Query: 196 LSEN 199
L N
Sbjct: 212 LHSN 215
Score = 59.3 bits (137), Expect = 4e-08
Identities = 90/433 (20%), Positives = 163/433 (37%), Gaps = 49/433 (11%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL- 74
+CP +C C+ + C+N L +P L T + L N + ++L A ++ +L L
Sbjct: 504 VCPEKCRCEGTI--VDCSNQKLVRIPSHLPEYVTDLRLNDNEV-SVLEATGIFKKLPNLR 560
Query: 75 --DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
++S NKI ++ F+ + ++ L L+ N L+ + F G I +
Sbjct: 561 KINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCV 620
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF LS++ L +NR+ T P + ++SL ++L P HL
Sbjct: 621 SNDTFAGLSSVRLLSLYDNRIT-----TITPGAFTTLVSLSTINLLSNP---FNCNCHLA 672
Query: 193 YLDL---SENLIQQVSRHGLPF-LKELKHLD--LNNNIIESVDQLGFHSLPSLRHLDLSD 246
+L ++ R PF LKE+ D + + + ++ P
Sbjct: 673 WLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCM 732
Query: 247 NNMTLIPTSALSKL-----SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERI 301
+ L L +++ LYL G +
Sbjct: 733 ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM--L 790
Query: 302 DSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRL 360
+ F + +L + ++ N ++R +P F+G L + + N + ++ E S + L
Sbjct: 791 TNYTFSNMSHLSTLILSYN-RLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 849
Query: 361 QELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKG 417
L + NP C+CSL WL SE++K Y++ +CS P +
Sbjct: 850 SHLALGTNPLHCDCSLRWL-----------------SEWVKAGYKEPGIARCSSPEPMAD 892
Query: 418 MLFVQIPESEFGC 430
L + P F C
Sbjct: 893 RLLLTTPTHRFQC 905
Score = 57.2 bits (132), Expect = 1e-07
Identities = 32/99 (32%), Positives = 52/99 (52%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + +L L L +N + + R LK+L+ L LN N ++ +
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F S P L LDLS+N + IP A ++++ +L L
Sbjct: 126 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL 164
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/217 (23%), Positives = 85/217 (39%), Gaps = 23/217 (10%)
Query: 221 NNNIIESVDQLGFHSLPS-----LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXX 275
+NNI++ + G +P+ + + L N++ IP A ++ L + +S
Sbjct: 287 SNNIVDCRGK-GLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISD 345
Query: 276 XXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNP 335
E I F ++LQ + +N N K+ + F
Sbjct: 346 IAPDAFQGLKSLTSLVLYGNKITE-IAKGLFDGLVSLQLLLLNAN-KINCLRVNTFQDLQ 403
Query: 336 KLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSG 394
L + + +N L+T+ F P+ +Q L ++ NPF C+C L WL +D+ T SG
Sbjct: 404 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIET--SG 461
Query: 395 NSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+CS P +L QI +F CS
Sbjct: 462 ------------ARCSSPRRLANKRISQIKSKKFRCS 486
Score = 46.0 bits (104), Expect = 4e-04
Identities = 30/134 (22%), Positives = 60/134 (44%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + + + N I + + F +++ +++S N + + DAF G
Sbjct: 304 NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLY 363
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ I F L +L+ L + N++ TF+ L +L +LSL +N + I
Sbjct: 364 GNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLF 423
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 424 APLQSIQTLHLAQN 437
Score = 45.6 bits (103), Expect = 5e-04
Identities = 38/173 (21%), Positives = 70/173 (40%), Gaps = 5/173 (2%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P + + LDL+ N I + ++ F L +LR L L DN +++I A L L L
Sbjct: 58 GIP--RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLR 115
Query: 268 LSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVP 327
L+ + I +AF +++ + + DN + +
Sbjct: 116 LN-KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL-DNNHISCIE 173
Query: 328 PRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL 379
F L + + NN + + + F + +++ L + N C+C L WL
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWL 226
Score = 45.6 bits (103), Expect = 5e-04
Identities = 32/114 (28%), Positives = 51/114 (44%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF QL L ++ NK+ L F+S ++ L+LS N ++ + + AF G
Sbjct: 104 AFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
IS I FR L LE L +NN + +F + ++ L L +N +
Sbjct: 164 LDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/99 (30%), Positives = 46/99 (46%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L NSI IP+ L+ +D+S+N I ++ LK L L L N I +
Sbjct: 312 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 371
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L SL+ L L+ N + + + L NL+ L L
Sbjct: 372 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSL 410
>AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein.
Length = 1534
Score = 70.5 bits (165), Expect = 1e-11
Identities = 43/135 (31%), Positives = 65/135 (48%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ IH F L L L N++ E F+ + L+ L L N + +P
Sbjct: 73 ITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNN 132
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R +LK+L L+ N I +++ F +L L L L++NN
Sbjct: 133 QALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNN 192
Query: 249 MTLIPTSALSKLSNL 263
+T IP S+ + + L
Sbjct: 193 ITTIPVSSFNHMPKL 207
Score = 65.7 bits (153), Expect = 4e-10
Identities = 44/170 (25%), Positives = 78/170 (45%), Gaps = 6/170 (3%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLY 68
S + +CP +C C+ C++ L +P ++ + L +N I ++L A ++
Sbjct: 505 SECNSDVVCPHKCRCE--ANVVECSSLKLTKIPERIPQSTAELRLNNNEI-SILEATGMF 561
Query: 69 TQLTVL---DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
+LT L ++S NK+ ++ FE + + L+L+ N L+ + F G
Sbjct: 562 KKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLR 621
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
IS IH +F L + L +N++ T P F+ L SL L+L N
Sbjct: 622 NNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 64.9 bits (151), Expect = 7e-10
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 2/163 (1%)
Query: 87 ENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERL 146
+N N+E L L+ N + R+ K+ F G +I + F D+ LERL
Sbjct: 57 KNIPRNTE--RLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERL 114
Query: 147 DFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSR 206
+ N+L F+ +L L L N+I IP L+ L L +N I +
Sbjct: 115 RLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEE 174
Query: 207 HGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L+ L+ L LNNN I ++ F+ +P LR L N++
Sbjct: 175 GAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/200 (25%), Positives = 78/200 (39%), Gaps = 5/200 (2%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L+A W A+ CP C C C L+ +P + + L N I
Sbjct: 20 LLLWAAAWRLGASA--CPALCTCTGT--TVDCHGTGLQAIPKNIPRNTERLELNGNNITR 75
Query: 61 L-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
+ F QL VL + N+I + F+ E+ L L+ N L L + F
Sbjct: 76 IHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQAL 135
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILD 179
I I + FR + L+ L N++ E F L L++L+L NN+I
Sbjct: 136 SRLDLSENAIQAIPRKAFRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITT 195
Query: 180 IPSANLGFVIHLEYLDLSEN 199
IP ++ + L L N
Sbjct: 196 IPVSSFNHMPKLRTFRLHSN 215
Score = 63.7 bits (148), Expect = 2e-09
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLD 75
CP C C + + C L +P L T + L N I ++ AF+ Y +L +D
Sbjct: 282 CPAMCTCSNGI--VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRID 339
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+S N+I ++ + F+ + L L N + L + F G +I+ I
Sbjct: 340 LSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPD 399
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSIL 178
F+DL L L +N++ + TF L +++ L L N +
Sbjct: 400 AFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFI 442
Score = 61.3 bits (142), Expect = 9e-09
Identities = 39/119 (32%), Positives = 59/119 (49%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I +I F L R+D SNN++ P+ F+ L SL L L N I D+P G +
Sbjct: 321 IKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGL 380
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L+ L L+ N I + L+ L L L +N I+S+ + F SL +++ L L+ N
Sbjct: 381 YTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQN 439
Score = 56.0 bits (129), Expect = 3e-07
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C C D + C+N +L +P + T + L N + + + L ++D+
Sbjct: 734 CPQECACLDTV--VRCSNKHLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDL 791
Query: 77 SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT 136
S NKI L + +F + S++ L LS N L+ + AF G +IS +
Sbjct: 792 SNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGI 851
Query: 137 FRDLSALERLDFSNNRL 153
F D+++L L N L
Sbjct: 852 FADVTSLSHLAIGANPL 868
Score = 54.4 bits (125), Expect = 1e-06
Identities = 33/134 (24%), Positives = 62/134 (46%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL +T + + N I + F ++R ++LSNN + + DAF G
Sbjct: 306 NLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLY 365
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+++ F L L+ L + N++ P+ F+ L +L +LSL +N I +
Sbjct: 366 GNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTF 425
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 426 TSLRAIQTLHLAQN 439
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/99 (34%), Positives = 49/99 (49%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + L L L EN I V R +KEL+ L LN N + +
Sbjct: 66 LELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLP 125
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F + +L LDLS+N + IP A ++L +L L
Sbjct: 126 ELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRL 164
Score = 51.2 bits (117), Expect = 9e-06
Identities = 48/220 (21%), Positives = 85/220 (38%), Gaps = 17/220 (7%)
Query: 213 KELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXX 272
+ + L+LN N I + + F L LR L L +N + + A + L L L+
Sbjct: 61 RNTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLN-RN 119
Query: 273 XXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFH 332
+ I +AF +L+ + ++ N ++ + F
Sbjct: 120 QLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLRLDKN-QISCIEEGAFR 178
Query: 333 GNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGKDSETTTK 391
L + + NN + T+ S F + +L+ + N C+C L WL + + T
Sbjct: 179 ALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQRPTI-- 236
Query: 392 KSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
F +CSGP L+G+ ++ +SEF CS
Sbjct: 237 -----GLF-------TQCSGPASLRGLNVAEVQKSEFSCS 264
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/114 (27%), Positives = 53/114 (46%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF+ +L L ++ N++ L F++N + L+LS N ++ + + AF G
Sbjct: 104 AFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLR 163
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
+IS I FR L LE L +NN + T +F + L+ L +N +
Sbjct: 164 LDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRLHSNHL 217
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/124 (29%), Positives = 56/124 (45%), Gaps = 1/124 (0%)
Query: 146 LDFSNNRLVTFEPE-TFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQV 204
L +NN + E F+ L+ LK ++L NN + +I + L L+ N ++ +
Sbjct: 545 LRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESI 604
Query: 205 SRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLS 264
L L+ L L NN I + F L ++R L L DN +T + A L +LS
Sbjct: 605 RSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLS 664
Query: 265 HLYL 268
L L
Sbjct: 665 TLNL 668
Score = 47.6 bits (108), Expect = 1e-04
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N +P L +L+ +DLS N I +S + +L L L+ N ++ +
Sbjct: 766 LYLDGNQFTLVPG-QLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIP 824
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L F L SLR L L N+++ + + +++LSHL
Sbjct: 825 PLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHL 861
Score = 46.4 bits (105), Expect = 3e-04
Identities = 33/111 (29%), Positives = 53/111 (47%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
F+ L+ L++++ SNN++ E FE +S+ L L N + I S + L L L
Sbjct: 561 FKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLML 620
Query: 197 SENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
N I + L+ ++ L L +N I +V F +L SL L+L N
Sbjct: 621 RNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 45.2 bits (102), Expect = 6e-04
Identities = 30/109 (27%), Positives = 47/109 (43%), Gaps = 21/109 (19%)
Query: 326 VPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQELEISGNPFACNCSLLWLWKLGK 384
+PP F G L + + N + TL+ F + L L I NP C+C L WL
Sbjct: 823 IPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL----- 877
Query: 385 DSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKGMLFVQIPESEFGC 430
S ++K Y++ +C+GP ++G L + P +F C
Sbjct: 878 ------------SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFEC 914
Score = 41.5 bits (93), Expect = 0.008
Identities = 36/120 (30%), Positives = 52/120 (43%), Gaps = 2/120 (1%)
Query: 151 NRLVTFEPETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGL 209
N + + P F P L+ + L NN I +I P A G + L L L N I + R
Sbjct: 319 NGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQG-LRSLNSLVLYGNKITDLPRGVF 377
Query: 210 PFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ L LN N I + F L +L L L DN + + + L + L+L+
Sbjct: 378 GGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLA 437
Score = 41.1 bits (92), Expect = 0.010
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 16/122 (13%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDR-LQELEISGNPF 370
LQ + +N N K+ + P F L+ + + +N +++L F R +Q L ++ NPF
Sbjct: 383 LQLLLLNAN-KINCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPF 441
Query: 371 ACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGC 430
C+C+L WL D T I+ +C+ P +L QI +F C
Sbjct: 442 ICDCNLKWL----ADFLRTN----------PIETSGARCASPRRLANKRIGQIKSKKFRC 487
Query: 431 SS 432
S+
Sbjct: 488 SA 489
Score = 40.7 bits (91), Expect = 0.013
Identities = 38/155 (24%), Positives = 66/155 (42%), Gaps = 4/155 (2%)
Query: 70 QLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDA-FVGXXXXXXXXXXXXE 128
+ V++ S K+ + +S +E+R L+NN + L+ F +
Sbjct: 520 EANVVECSSLKLTKIPERIPQSTAELR---LNNNEISILEATGMFKKLTHLKKINLSNNK 576
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
+S I F +++ L + N+L + F L L+ L LRNN I I + + +
Sbjct: 577 VSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGL 636
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
++ L L +N I VS L+ L L+L N
Sbjct: 637 RNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLAN 671
Score = 39.1 bits (87), Expect = 0.041
Identities = 31/99 (31%), Positives = 43/99 (43%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L N I IP L +DLS N I +++ L+ L L L N I +
Sbjct: 314 IRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLP 373
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L +L+ L L+ N + I A L NLS L L
Sbjct: 374 RGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSL 412
Score = 38.7 bits (86), Expect = 0.054
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 10/176 (5%)
Query: 238 SLRHLDLSDNNMTLIP-TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXX 296
S L L++N ++++ T KL++L + LS
Sbjct: 541 STAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQ 600
Query: 297 XXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHG--NPKLTNIYMKNNALETLEASH 354
E I S F L+ + + +N ++ + F G N +L ++Y +N + T+
Sbjct: 601 L-ESIRSGMFRGLDGLRTLMLRNN-RISCIHNDSFTGLRNVRLLSLY--DNQITTVSPGA 656
Query: 355 FP-IDRLQELEISGNPFACNCSLLWL--WKLGKDSETTTKKSGNSSEFLKIDYEDV 407
F + L L + NPF CNC L WL W + T + N +I +DV
Sbjct: 657 FDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDV 712
Score = 34.7 bits (76), Expect = 0.88
Identities = 23/62 (37%), Positives = 31/62 (50%)
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L K L+ +DL+NN I S+ F ++ L L LS N + IP A L +L L L
Sbjct: 780 LSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSL 839
Query: 269 SG 270
G
Sbjct: 840 HG 841
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 70.5 bits (165), Expect = 1e-11
Identities = 48/168 (28%), Positives = 71/168 (42%), Gaps = 3/168 (1%)
Query: 9 SAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
S A CP C C + + C L +P L + L N+I + AF
Sbjct: 308 SCNANSISCPSPCTCSNNI--VDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQ 365
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
Y +L +DIS N+I D+ + F+ + L L N + + K F G
Sbjct: 366 YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNAN 425
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
+I+ + V TF+DL L L +N+L T F PL S++ L L N
Sbjct: 426 KINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQN 473
Score = 66.5 bits (155), Expect = 2e-10
Identities = 44/152 (28%), Positives = 66/152 (43%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L+L N + R+ K F G ++S I F+DL LERL + N+L
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 161
Query: 158 PETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKH 217
F+ L L L N I IP + ++ L L N I + L++L+
Sbjct: 162 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEI 221
Query: 218 LDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM 249
L LNNN I + F+ +P +R L L N++
Sbjct: 222 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 64.5 bits (150), Expect = 1e-09
Identities = 41/140 (29%), Positives = 67/140 (47%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I+ I F L L L +N++ E F+ L L+ L L N + +P
Sbjct: 109 ITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQST 168
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
L LDLSEN IQ + R + ++K+L L+NN I ++ F +L L L L++NN
Sbjct: 169 PKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNN 228
Query: 249 MTLIPTSALSKLSNLSHLYL 268
++ I ++ + + + L L
Sbjct: 229 ISRILVTSFNHMPKIRTLRL 248
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/182 (24%), Positives = 88/182 (48%), Gaps = 4/182 (2%)
Query: 20 RCMCDDALRAASCANANLEIV-PIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDISY 78
RC + R+ + +++V P + E T+++ ++ + + +L +T L ++
Sbjct: 520 RCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRI--PSHLPEYVTDLRLND 577
Query: 79 NKILDLGSEN-FESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTF 137
N++ L + F+ +R +NLSNN +K + + AF G ++ +H + F
Sbjct: 578 NEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVF 637
Query: 138 RDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
R LS L+ L +N + +TF LSS+++LSL +N I I ++ L ++L
Sbjct: 638 RGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLL 697
Query: 198 EN 199
N
Sbjct: 698 SN 699
Score = 62.1 bits (144), Expect = 5e-09
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLD 75
CP +C C A + C L VP + A ++L N I + F L VL
Sbjct: 70 CPTKCTCSAA--SVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 127
Query: 76 ISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
+ N++ + F+ ++ L L+ N L+ L + F +I I +
Sbjct: 128 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 187
Query: 136 TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLD 195
FR ++ ++ L NN + E F L L+IL+L NN+I I + + + L
Sbjct: 188 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 247
Query: 196 LSEN 199
L N
Sbjct: 248 LHSN 251
Score = 59.3 bits (137), Expect = 4e-08
Identities = 90/433 (20%), Positives = 163/433 (37%), Gaps = 49/433 (11%)
Query: 16 LCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL- 74
+CP +C C+ + C+N L +P L T + L N + ++L A ++ +L L
Sbjct: 540 VCPEKCRCEGTI--VDCSNQKLVRIPSHLPEYVTDLRLNDNEV-SVLEATGIFKKLPNLR 596
Query: 75 --DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNI 132
++S NKI ++ F+ + ++ L L+ N L+ + F G I +
Sbjct: 597 KINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCV 656
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
TF LS++ L +NR+ T P + ++SL ++L P HL
Sbjct: 657 SNDTFAGLSSVRLLSLYDNRIT-----TITPGAFTTLVSLSTINLLSNP---FNCNCHLA 708
Query: 193 YLDL---SENLIQQVSRHGLPF-LKELKHLD--LNNNIIESVDQLGFHSLPSLRHLDLSD 246
+L ++ R PF LKE+ D + + + ++ P
Sbjct: 709 WLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCM 768
Query: 247 NNMTLIPTSALSKL-----SNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERI 301
+ L L +++ LYL G +
Sbjct: 769 ETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISM--L 826
Query: 302 DSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL-EASHFPIDRL 360
+ F + +L + ++ N ++R +P F+G L + + N + ++ E S + L
Sbjct: 827 TNYTFSNMSHLSTLILSYN-RLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 885
Query: 361 QELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYED---VKCSGPLQLKG 417
L + NP C+CSL WL SE++K Y++ +CS P +
Sbjct: 886 SHLALGTNPLHCDCSLRWL-----------------SEWVKAGYKEPGIARCSSPEPMAD 928
Query: 418 MLFVQIPESEFGC 430
L + P F C
Sbjct: 929 RLLLTTPTHRFQC 941
Score = 57.2 bits (132), Expect = 1e-07
Identities = 32/99 (32%), Positives = 52/99 (52%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
L L N+I I + + +L L L +N + + R LK+L+ L LN N ++ +
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLP 161
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+L F S P L LDLS+N + IP A ++++ +L L
Sbjct: 162 ELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL 200
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/217 (23%), Positives = 85/217 (39%), Gaps = 23/217 (10%)
Query: 221 NNNIIESVDQLGFHSLPS-----LRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXX 275
+NNI++ + G +P+ + + L N++ IP A ++ L + +S
Sbjct: 323 SNNIVDCRGK-GLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISD 381
Query: 276 XXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNP 335
E I F ++LQ + +N N K+ + F
Sbjct: 382 IAPDAFQGLKSLTSLVLYGNKITE-IAKGLFDGLVSLQLLLLNAN-KINCLRVNTFQDLQ 439
Query: 336 KLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWLWKLGKDSETTTKKSG 394
L + + +N L+T+ F P+ +Q L ++ NPF C+C L WL +D+ T SG
Sbjct: 440 NLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIET--SG 497
Query: 395 NSSEFLKIDYEDVKCSGPLQLKGMLFVQIPESEFGCS 431
+CS P +L QI +F CS
Sbjct: 498 ------------ARCSSPRRLANKRISQIKSKKFRCS 522
Score = 46.0 bits (104), Expect = 4e-04
Identities = 30/134 (22%), Positives = 60/134 (44%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXX 125
NL + + + N I + + F +++ +++S N + + DAF G
Sbjct: 340 NLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLY 399
Query: 126 XXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANL 185
+I+ I F L +L+ L + N++ TF+ L +L +LSL +N + I
Sbjct: 400 GNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLF 459
Query: 186 GFVIHLEYLDLSEN 199
+ ++ L L++N
Sbjct: 460 APLQSIQTLHLAQN 473
Score = 45.6 bits (103), Expect = 5e-04
Identities = 38/173 (21%), Positives = 70/173 (40%), Gaps = 5/173 (2%)
Query: 208 GLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLY 267
G+P + + LDL+ N I + ++ F L +LR L L DN +++I A L L L
Sbjct: 94 GIP--RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLR 151
Query: 268 LSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVP 327
L+ + I +AF +++ + + DN + +
Sbjct: 152 LN-KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQL-DNNHISCIE 209
Query: 328 PRLFHGNPKLTNIYMKNNALETLEASHF-PIDRLQELEISGNPFACNCSLLWL 379
F L + + NN + + + F + +++ L + N C+C L WL
Sbjct: 210 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWL 262
Score = 45.6 bits (103), Expect = 5e-04
Identities = 32/114 (28%), Positives = 51/114 (44%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXX 123
AF QL L ++ NK+ L F+S ++ L+LS N ++ + + AF G
Sbjct: 140 AFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQ 199
Query: 124 XXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
IS I FR L LE L +NN + +F + ++ L L +N +
Sbjct: 200 LDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 253
Score = 41.1 bits (92), Expect = 0.010
Identities = 30/99 (30%), Positives = 46/99 (46%)
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVD 229
+ L NSI IP+ L+ +D+S+N I ++ LK L L L N I +
Sbjct: 348 IRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIA 407
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ F L SL+ L L+ N + + + L NL+ L L
Sbjct: 408 KGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSL 446
>BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like family,
member 4 protein.
Length = 837
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 12/222 (5%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
++ E IQ +S +P K L +N N I+ VD F L L L N +T+I
Sbjct: 359 VNCQEKNIQSMSEL-IPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIK 417
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
L+NL LYL+G E I + F NLQ
Sbjct: 418 GDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKE-ISAGTFDSMPNLQ 476
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQ---ELEISGNPF 370
+++N+N+ ++ +P +F G P L + ++NN L S +D+LQ ++++ GNP+
Sbjct: 477 LLYLNNNL-LKSLPVYIFSGAP-LARLNLRNNKFMYLPVSGV-LDQLQSLTQIDLEGNPW 533
Query: 371 ACNCSL----LWLWKLGKDSETTTKKSGNSSEFLKIDYEDVK 408
C C L LW+ KL K +F I+ + +K
Sbjct: 534 DCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLK 575
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I ++ V F D L+ L +N++ + + F L++L+ L L N I + +
Sbjct: 389 IKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGL 448
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
+L+YL L NLI+++S + L+ L LNNN+++S+ F P L L+L +N
Sbjct: 449 HNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNK 507
Query: 249 MTLIPTS-ALSKLSNLSHLYLSG 270
+P S L +L +L+ + L G
Sbjct: 508 FMYLPVSGVLDQLQSLTQIDLEG 530
Score = 63.7 bits (148), Expect = 2e-09
Identities = 46/156 (29%), Positives = 69/156 (44%), Gaps = 2/156 (1%)
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
S HLN NNFL L + F+ ++ NI F LSAL++L +NN
Sbjct: 59 SNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNE 118
Query: 153 LVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL 212
L +TF + +L+ L N I I + L+ L L++NLI + + F
Sbjct: 119 LKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRF- 177
Query: 213 KELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDN 247
L HLD+ N I+ + +G + + L L DN
Sbjct: 178 ASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDN 213
Score = 62.1 bits (144), Expect = 5e-09
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 1/122 (0%)
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
++ TF + S L NN+L E F LS+LK L L NN + + + + +L
Sbjct: 74 LYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENL 133
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
EYL NLI+ + R L +LK L LN+N+I + F SL HLD+ N +
Sbjct: 134 EYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR-FASLTHLDIRGNRIQK 192
Query: 252 IP 253
+P
Sbjct: 193 LP 194
Score = 52.4 bits (120), Expect = 4e-06
Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 6/145 (4%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L+ N + L F + S L+L NN L+ ++ AF+G E+ +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF + LE L N + E F L LK+L L +N I +P N+ L +
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPD-NIFRFASLTH 182
Query: 194 LDLSENLIQQVSRHGLPFLKELKHL 218
LD+ N IQ+ LP++ L+H+
Sbjct: 183 LDIRGNRIQK-----LPYIGVLEHI 202
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/125 (27%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+F NN L P TF S L L NN + +I + L+ L L+ N ++ +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
++ L++L + N+I+ +++ F+ L L+ L L+DN ++ +P + + + ++L+H
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDN-IFRFASLTH 182
Query: 266 LYLSG 270
L + G
Sbjct: 183 LDIRG 187
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 51 MNLTHNAIDNLLY--AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+N +N + N+LY F ++ L + NK+ ++ F S ++ L+L+NN LK L
Sbjct: 64 LNFQNNFL-NILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
D F+G I I F L L+ L N+ L++F P+ +SL
Sbjct: 123 RADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVL-ILNDNLISFLPDNIFRFASLT 181
Query: 169 ILSLRNNSILDIP----SANLGFVIHLEYLD 195
L +R N I +P ++G V+ L+ D
Sbjct: 182 HLDIRGNRIQKLPYIGVLEHIGRVVELQLED 212
Score = 41.1 bits (92), Expect = 0.010
Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L ++ N I D+ +F + L+L +N + + D F +I ++
Sbjct: 382 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 441
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+ F L L+ L N + TF+ + +L++L L NN + +P + L
Sbjct: 442 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP-VYIFSGAPLAR 500
Query: 194 LDLSENLIQQVSRHG-LPFLKELKHLDLNNN 223
L+L N + G L L+ L +DL N
Sbjct: 501 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 40.7 bits (91), Expect = 0.013
Identities = 29/115 (25%), Positives = 54/115 (46%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
++L + N + + F L +L L +N I I + +L L L+ N I++
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
+ L L++L L N+I+ + F S+P+L+ L L++N + +P S
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 494
Score = 38.3 bits (85), Expect = 0.071
Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXX 276
HL+ NN + + F + L L +N + I A LS L L+L+
Sbjct: 63 HLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 277 XXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPK 336
+ I+ AF L+ + +NDN+ + +P +F
Sbjct: 123 RADTFLGIENLEYLQADYNLI-KYIERGAFNKLHKLKVLILNDNL-ISFLPDNIFRF-AS 179
Query: 337 LTNIYMKNNALETLEASHF--PIDRLQELEISGNPFACNCSLL 377
LT++ ++ N ++ L I R+ EL++ NP+ C+C LL
Sbjct: 180 LTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLL 222
Score = 35.5 bits (78), Expect = 0.50
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
++ + L ++ N I+ V + L L L +N I + FH+L +LR L L+ N
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ + S L NL +LYL
Sbjct: 437 IERLYPEIFSGLHNLQYLYL 456
>AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein
protein.
Length = 689
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 12/222 (5%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
++ E IQ +S +P K L +N N I+ VD F L L L N +T+I
Sbjct: 211 VNCQEKNIQSMSEL-IPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIK 269
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
L+NL LYL+G E I + F NLQ
Sbjct: 270 GDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKE-ISAGTFDSMPNLQ 328
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQ---ELEISGNPF 370
+++N+N+ ++ +P +F G P L + ++NN L S +D+LQ ++++ GNP+
Sbjct: 329 LLYLNNNL-LKSLPVYIFSGAP-LARLNLRNNKFMYLPVSGV-LDQLQSLTQIDLEGNPW 385
Query: 371 ACNCSL----LWLWKLGKDSETTTKKSGNSSEFLKIDYEDVK 408
C C L LW+ KL K +F I+ + +K
Sbjct: 386 DCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLK 427
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I ++ V F D L+ L +N++ + + F L++L+ L L N I + +
Sbjct: 241 IKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGL 300
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
+L+YL L NLI+++S + L+ L LNNN+++S+ F P L L+L +N
Sbjct: 301 HNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNK 359
Query: 249 MTLIPTS-ALSKLSNLSHLYLSG 270
+P S L +L +L+ + L G
Sbjct: 360 FMYLPVSGVLDQLQSLTQIDLEG 382
Score = 41.1 bits (92), Expect = 0.010
Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L ++ N I D+ +F + L+L +N + + D F +I ++
Sbjct: 234 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 293
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+ F L L+ L N + TF+ + +L++L L NN + +P + L
Sbjct: 294 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP-VYIFSGAPLAR 352
Query: 194 LDLSENLIQQVSRHG-LPFLKELKHLDLNNN 223
L+L N + G L L+ L +DL N
Sbjct: 353 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 383
Score = 40.7 bits (91), Expect = 0.013
Identities = 29/115 (25%), Positives = 54/115 (46%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
++L + N + + F L +L L +N I I + +L L L+ N I++
Sbjct: 232 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 291
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
+ L L++L L N+I+ + F S+P+L+ L L++N + +P S
Sbjct: 292 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 346
Score = 35.5 bits (78), Expect = 0.50
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
++ + L ++ N I+ V + L L L +N I + FH+L +LR L L+ N
Sbjct: 229 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 288
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ + S L NL +LYL
Sbjct: 289 IERLYPEIFSGLHNLQYLYL 308
Score = 32.3 bits (70), Expect = 4.7
Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 312 LQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF--PIDRLQELEISGNP 369
L+ + +NDN+ + +P +F LT++ ++ N ++ L I R+ EL++ NP
Sbjct: 9 LKVLILNDNL-ISFLPDNIFRF-ASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNP 66
Query: 370 FACNCSLL 377
+ C+C LL
Sbjct: 67 WNCSCDLL 74
>AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein.
Length = 837
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 12/222 (5%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
++ E IQ +S +P K L +N N I+ VD F L L L N +T+I
Sbjct: 359 VNCQEKNIQSMSEL-IPKPLNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIK 417
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
L+NL LYL+G E I + F NLQ
Sbjct: 418 GDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKE-ISAGTFDSMPNLQ 476
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQ---ELEISGNPF 370
+++N+N+ ++ +P +F G P L + ++NN L S +D+LQ ++++ GNP+
Sbjct: 477 LLYLNNNL-LKSLPVYIFSGAP-LARLNLRNNKFMYLPVSGV-LDQLQSLTQIDLEGNPW 533
Query: 371 ACNCSL----LWLWKLGKDSETTTKKSGNSSEFLKIDYEDVK 408
C C L LW+ KL K +F I+ + +K
Sbjct: 534 DCTCDLVALKLWVEKLSDGIVVKELKCETPVQFANIELKSLK 575
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I ++ V F D L+ L +N++ + + F L++L+ L L N I + +
Sbjct: 389 IKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGL 448
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
+L+YL L NLI+++S + L+ L LNNN+++S+ F P L L+L +N
Sbjct: 449 HNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNK 507
Query: 249 MTLIPTS-ALSKLSNLSHLYLSG 270
+P S L +L +L+ + L G
Sbjct: 508 FMYLPVSGVLDQLQSLTQIDLEG 530
Score = 63.7 bits (148), Expect = 2e-09
Identities = 46/156 (29%), Positives = 69/156 (44%), Gaps = 2/156 (1%)
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
S HLN NNFL L + F+ ++ NI F LSAL++L +NN
Sbjct: 59 SNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNE 118
Query: 153 LVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL 212
L +TF + +L+ L N I I + L+ L L++NLI + + F
Sbjct: 119 LKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFRF- 177
Query: 213 KELKHLDLNNNIIESVDQLG-FHSLPSLRHLDLSDN 247
L HLD+ N I+ + +G + + L L DN
Sbjct: 178 ASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDN 213
Score = 62.1 bits (144), Expect = 5e-09
Identities = 41/122 (33%), Positives = 60/122 (49%), Gaps = 1/122 (0%)
Query: 132 IHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
++ TF + S L NN+L E F LS+LK L L NN + + + + +L
Sbjct: 74 LYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILRADTFLGIENL 133
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTL 251
EYL NLI+ + R L +LK L LN+N+I + F SL HLD+ N +
Sbjct: 134 EYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDNIFR-FASLTHLDIRGNRIQK 192
Query: 252 IP 253
+P
Sbjct: 193 LP 194
Score = 52.4 bits (120), Expect = 4e-06
Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 6/145 (4%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L+ N + L F + S L+L NN L+ ++ AF+G E+ +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
TF + LE L N + E F L LK+L L +N I +P N+ L +
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPD-NIFRFASLTH 182
Query: 194 LDLSENLIQQVSRHGLPFLKELKHL 218
LD+ N IQ+ LP++ L+H+
Sbjct: 183 LDIRGNRIQK-----LPYIGVLEHI 202
Score = 52.4 bits (120), Expect = 4e-06
Identities = 34/125 (27%), Positives = 66/125 (52%), Gaps = 1/125 (0%)
Query: 146 LDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVS 205
L+F NN L P TF S L L NN + +I + L+ L L+ N ++ +
Sbjct: 64 LNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKILR 123
Query: 206 RHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSH 265
++ L++L + N+I+ +++ F+ L L+ L L+DN ++ +P + + + ++L+H
Sbjct: 124 ADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILNDNLISFLPDN-IFRFASLTH 182
Query: 266 LYLSG 270
L + G
Sbjct: 183 LDIRG 187
Score = 50.0 bits (114), Expect = 2e-05
Identities = 42/151 (27%), Positives = 69/151 (45%), Gaps = 8/151 (5%)
Query: 51 MNLTHNAIDNLLY--AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRL 108
+N +N + N+LY F ++ L + NK+ ++ F S ++ L+L+NN LK L
Sbjct: 64 LNFQNNFL-NILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 109 DKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
D F+G I I F L L+ L N+ L++F P+ +SL
Sbjct: 123 RADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVL-ILNDNLISFLPDNIFRFASLT 181
Query: 169 ILSLRNNSILDIP----SANLGFVIHLEYLD 195
L +R N I +P ++G V+ L+ D
Sbjct: 182 HLDIRGNRIQKLPYIGVLEHIGRVVELQLED 212
Score = 41.1 bits (92), Expect = 0.010
Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L ++ N I D+ +F + L+L +N + + D F +I ++
Sbjct: 382 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 441
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+ F L L+ L N + TF+ + +L++L L NN + +P + L
Sbjct: 442 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP-VYIFSGAPLAR 500
Query: 194 LDLSENLIQQVSRHG-LPFLKELKHLDLNNN 223
L+L N + G L L+ L +DL N
Sbjct: 501 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 531
Score = 40.7 bits (91), Expect = 0.013
Identities = 29/115 (25%), Positives = 54/115 (46%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
++L + N + + F L +L L +N I I + +L L L+ N I++
Sbjct: 380 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 439
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
+ L L++L L N+I+ + F S+P+L+ L L++N + +P S
Sbjct: 440 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 494
Score = 38.3 bits (85), Expect = 0.071
Identities = 38/163 (23%), Positives = 66/163 (40%), Gaps = 5/163 (3%)
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXX 276
HL+ NN + + F + L L +N + I A LS L L+L+
Sbjct: 63 HLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAFLGLSALKQLHLNNNELKIL 122
Query: 277 XXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPK 336
+ I+ AF L+ + +NDN+ + +P +F
Sbjct: 123 RADTFLGIENLEYLQADYNLI-KYIERGAFNKLHKLKVLILNDNL-ISFLPDNIFRF-AS 179
Query: 337 LTNIYMKNNALETLEASHF--PIDRLQELEISGNPFACNCSLL 377
LT++ ++ N ++ L I R+ EL++ NP+ C+C LL
Sbjct: 180 LTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLL 222
Score = 35.5 bits (78), Expect = 0.50
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
++ + L ++ N I+ V + L L L +N I + FH+L +LR L L+ N
Sbjct: 377 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 436
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ + S L NL +LYL
Sbjct: 437 IERLYPEIFSGLHNLQYLYL 456
>BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein.
Length = 677
Score = 69.7 bits (163), Expect = 3e-11
Identities = 71/255 (27%), Positives = 110/255 (43%), Gaps = 16/255 (6%)
Query: 23 CDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI 81
C + R SC NA L +P P+ T + LT N+I ++ AFN L LD+S N I
Sbjct: 298 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 357
Query: 82 LD--LGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRD 139
+G + F+ ++ N+ N L ++ + I ++ D
Sbjct: 358 TSSGIGPKAFKLLKKLMRSNMDGNNLIQIPSQL---PSTLEELKVNENNLQAIDEESLSD 414
Query: 140 LSALERLDFSNNRL--VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLS 197
L+ L L+ N L P F+PL SL L L N IP G +E L L
Sbjct: 415 LNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ---GLPGSIEELYLE 471
Query: 198 ENLIQQVSRHGLPFLKELKHLDLNNNIIES--VDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
N I++++ +++ + L N IE + L + + +L +DLS N + +P S
Sbjct: 472 NNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVP-S 530
Query: 256 ALSKLSNLSHLYLSG 270
L K +L HL L G
Sbjct: 531 YLPK--SLLHLVLLG 543
>BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine rich
transmembrane protein 1 protein.
Length = 674
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/217 (27%), Positives = 94/217 (43%), Gaps = 8/217 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL--KELKHLDLNNN 223
SL+ L L++N++ I +L + LE L L +N + VS F K+LK L L+ N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ S+ H+L LR L DN ++ IP A L++L L L G
Sbjct: 188 HLSSIPSGLPHTLEELR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + +LQK+++ DN + +P +L + +
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLN-LPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLS 302
Query: 344 NNALETLEASHFP-IDRLQELEISGNPFACNCSLLWL 379
NN L TL F + L +L + NP+ C C+L+WL
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWL 339
Score = 63.7 bits (148), Expect = 2e-09
Identities = 68/259 (26%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 15 TLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL 74
T CP C CD+ C + L +P + +AT + L +N I+N +L T++ V
Sbjct: 52 TTCPSVCRCDNGF--IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNV- 108
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ Y DL +R L+L +N ++ + +D+ +S + +
Sbjct: 109 QVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI 168
Query: 135 Q--TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F D L+ L S N L + P +L+ L L +N I IP + L
Sbjct: 169 EEDAFADSKQLKLLFLSRNHLSSI-PSGLP--HTLEELRLDDNRISTIPLHAFKGLNSLR 225
Query: 193 YLDLSENLI--QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L L NL+ Q+++ L+ L L L N + + L S L+ L L DN ++
Sbjct: 226 RLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL-AAPPLNLPS-AHLQKLYLQDNAIS 283
Query: 251 LIPTSALSKLSNLSHLYLS 269
IP + L+K+ L L LS
Sbjct: 284 HIPYNTLAKMRELERLDLS 302
Score = 58.0 bits (134), Expect = 8e-08
Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 7/176 (3%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
LD + + + + F + +++ L LS N L + IS I
Sbjct: 158 LDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIP 214
Query: 134 VQTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F+ L++L RL N L +TF L +L LSL NS L P NL HL
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNS-LAAPPLNLPSA-HL 272
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ L L +N I + + L ++EL+ LDL+NN + ++ + F L +L L L +N
Sbjct: 273 QKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILD--LGSENFESN 92
+L +P L + L N I + L+AF L L + N + + + + F
Sbjct: 188 HLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRL 247
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ L+L N L + + IS+I T + LERLD SNN
Sbjct: 248 QNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNN 305
Query: 153 LVTFEPETFEPLSSLKILSLRNN 175
L T F+ L +L L LRNN
Sbjct: 306 LTTLPRGLFDDLGNLAQLLLRNN 328
>AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein.
Length = 674
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/217 (27%), Positives = 94/217 (43%), Gaps = 8/217 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL--KELKHLDLNNN 223
SL+ L L++N++ I +L + LE L L +N + VS F K+LK L L+ N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ S+ H+L LR L DN ++ IP A L++L L L G
Sbjct: 188 HLSSIPSGLPHTLEELR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + +LQK+++ DN + +P +L + +
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLN-LPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLS 302
Query: 344 NNALETLEASHFP-IDRLQELEISGNPFACNCSLLWL 379
NN L TL F + L +L + NP+ C C+L+WL
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWL 339
Score = 63.7 bits (148), Expect = 2e-09
Identities = 68/259 (26%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 15 TLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL 74
T CP C CD+ C + L +P + +AT + L +N I+N +L T++ V
Sbjct: 52 TTCPSVCRCDNGF--IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNV- 108
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ Y DL +R L+L +N ++ + +D+ +S + +
Sbjct: 109 QVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI 168
Query: 135 Q--TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F D L+ L S N L + P +L+ L L +N I IP + L
Sbjct: 169 EEDAFADSKQLKLLFLSRNHLSSI-PSGLP--HTLEELRLDDNRISTIPLHAFKGLNSLR 225
Query: 193 YLDLSENLI--QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L L NL+ Q+++ L+ L L L N + + L S L+ L L DN ++
Sbjct: 226 RLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL-AAPPLNLPS-AHLQKLYLQDNAIS 283
Query: 251 LIPTSALSKLSNLSHLYLS 269
IP + L+K+ L L LS
Sbjct: 284 HIPYNTLAKMRELERLDLS 302
Score = 58.0 bits (134), Expect = 8e-08
Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 7/176 (3%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
LD + + + + F + +++ L LS N L + IS I
Sbjct: 158 LDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIP 214
Query: 134 VQTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F+ L++L RL N L +TF L +L LSL NS L P NL HL
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNS-LAAPPLNLPSA-HL 272
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ L L +N I + + L ++EL+ LDL+NN + ++ + F L +L L L +N
Sbjct: 273 QKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILD--LGSENFESN 92
+L +P L + L N I + L+AF L L + N + + + + F
Sbjct: 188 HLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRL 247
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ L+L N L + + IS+I T + LERLD SNN
Sbjct: 248 QNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNN 305
Query: 153 LVTFEPETFEPLSSLKILSLRNN 175
L T F+ L +L L LRNN
Sbjct: 306 LTTLPRGLFDDLGNLAQLLLRNN 328
>AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat
transmembrane protein FLRT1 protein.
Length = 674
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/217 (27%), Positives = 94/217 (43%), Gaps = 8/217 (3%)
Query: 166 SLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL--KELKHLDLNNN 223
SL+ L L++N++ I +L + LE L L +N + VS F K+LK L L+ N
Sbjct: 128 SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRN 187
Query: 224 IIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXX 283
+ S+ H+L LR L DN ++ IP A L++L L L G
Sbjct: 188 HLSSIPSGLPHTLEELR---LDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTF 244
Query: 284 XXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMK 343
+ + +LQK+++ DN + +P +L + +
Sbjct: 245 SRLQNLTELSLVRNSLAAPPLN-LPSAHLQKLYLQDNA-ISHIPYNTLAKMRELERLDLS 302
Query: 344 NNALETLEASHFP-IDRLQELEISGNPFACNCSLLWL 379
NN L TL F + L +L + NP+ C C+L+WL
Sbjct: 303 NNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWL 339
Score = 63.7 bits (148), Expect = 2e-09
Identities = 68/259 (26%), Positives = 111/259 (42%), Gaps = 12/259 (4%)
Query: 15 TLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVL 74
T CP C CD+ C + L +P + +AT + L +N I+N +L T++ V
Sbjct: 52 TTCPSVCRCDNGF--IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNV- 108
Query: 75 DISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHV 134
+ Y DL +R L+L +N ++ + +D+ +S + +
Sbjct: 109 QVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI 168
Query: 135 Q--TFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLE 192
+ F D L+ L S N L + P +L+ L L +N I IP + L
Sbjct: 169 EEDAFADSKQLKLLFLSRNHLSSI-PSGLP--HTLEELRLDDNRISTIPLHAFKGLNSLR 225
Query: 193 YLDLSENLI--QQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMT 250
L L NL+ Q+++ L+ L L L N + + L S L+ L L DN ++
Sbjct: 226 RLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSL-AAPPLNLPS-AHLQKLYLQDNAIS 283
Query: 251 LIPTSALSKLSNLSHLYLS 269
IP + L+K+ L L LS
Sbjct: 284 HIPYNTLAKMRELERLDLS 302
Score = 58.0 bits (134), Expect = 8e-08
Identities = 51/176 (28%), Positives = 80/176 (45%), Gaps = 7/176 (3%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
LD + + + + F + +++ L LS N L + IS I
Sbjct: 158 LDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGL---PHTLEELRLDDNRISTIP 214
Query: 134 VQTFRDLSALERLDFSNNRLVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHL 191
+ F+ L++L RL N L +TF L +L LSL NS L P NL HL
Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNS-LAAPPLNLPSA-HL 272
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+ L L +N I + + L ++EL+ LDL+NN + ++ + F L +L L L +N
Sbjct: 273 QKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
Score = 41.1 bits (92), Expect = 0.010
Identities = 39/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILD--LGSENFESN 92
+L +P L + L N I + L+AF L L + N + + + + F
Sbjct: 188 HLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRL 247
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ L+L N L + + IS+I T + LERLD SNN
Sbjct: 248 QNLTELSLVRNSLAAPPLN--LPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNN 305
Query: 153 LVTFEPETFEPLSSLKILSLRNN 175
L T F+ L +L L LRNN
Sbjct: 306 LTTLPRGLFDDLGNLAQLLLRNN 328
>AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9
protein.
Length = 1032
Score = 69.3 bits (162), Expect = 3e-11
Identities = 63/226 (27%), Positives = 107/226 (47%), Gaps = 13/226 (5%)
Query: 50 LMNLTHNAIDNLL-YAFNLYTQLTVLDISYNKI---LDLGSENFESNSEMR---HLNLSN 102
+++L+ N +D ++F +L LD+SYN + NF + +R HL+L++
Sbjct: 525 VLDLSRNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAH 584
Query: 103 NFL-----KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
N + ++L + ++++ F+ LS L LD S NRL T
Sbjct: 585 NNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLL 644
Query: 158 PETFEPL-SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
P+T L SL++L LR+N + +L F+ LE LDL+ N ++ ++ LP L+
Sbjct: 645 PQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNRLKALTNGSLPAGTRLR 704
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSN 262
LD++ N I V F LR L+LS N + + S L++
Sbjct: 705 RLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLAS 750
Score = 55.6 bits (128), Expect = 4e-07
Identities = 92/357 (25%), Positives = 142/357 (39%), Gaps = 35/357 (9%)
Query: 86 SENFESNSEMRH--LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISN-IHVQTFRDLSA 142
SE+F N + L+LS N L + + F IS ++ F L+
Sbjct: 463 SEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTG 522
Query: 143 LERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI---LDIPSANLGFVIHLE---YLDL 196
L+ LD S N+L + +F L L+ L L NS + N FV HL +L L
Sbjct: 523 LQVLDLSRNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSL 582
Query: 197 SENLIQ-QVSRHGLPFLKELKHLDLNNNIIESVDQLG------FHSLPSLRHLDLSDNNM 249
+ N I QVS+ L+ LD + N + + G F L L LDLS N +
Sbjct: 583 AHNNIHSQVSQQLCS--TSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRL 640
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
TL+P + + +L L L + + + +
Sbjct: 641 HTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNRL-KALTNGSLPA 699
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PI-DRLQELEIS 366
L+++ ++ N + V P F +L + + NAL+T++ S F P+ LQ L++S
Sbjct: 700 GTRLRRLDVSCN-SISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVS 758
Query: 367 GNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGM-LFVQ 422
NP C C ++ L E G S VKC P QL+G+ +F Q
Sbjct: 759 ANPLHCACGAAFMDFL---LEVQAAVPGLPSR--------VKCGSPGQLQGLSIFAQ 804
Score = 55.6 bits (128), Expect = 4e-07
Identities = 69/234 (29%), Positives = 99/234 (42%), Gaps = 16/234 (6%)
Query: 51 MNLTHNAIDNLLYA--FNLYTQLTVLDISYNKILDLGSEN-FESNSEMRHLNLSNN---F 104
+ L+HN I + F T L VLD+S NK LDL E+ F + L+LS N F
Sbjct: 501 LRLSHNCISQAVNGSQFLPLTGLQVLDLSRNK-LDLYHEHSFTELPRLEALDLSYNSQPF 559
Query: 105 LKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDL--SALERLDFSNNRLVTFEPET-- 160
+ F +NIH Q + L ++L LDFS N L E
Sbjct: 560 GMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDL 619
Query: 161 ----FEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
F+ LS L L L N + + P L+ L L +N + L FL +L
Sbjct: 620 YLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKL 679
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ LDL N ++++ + LR LD+S N+++ + SK L L LS
Sbjct: 680 EVLDLAGNRLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLS 733
Score = 50.8 bits (116), Expect = 1e-05
Identities = 71/250 (28%), Positives = 111/250 (44%), Gaps = 36/250 (14%)
Query: 32 CANANLEIVPIQLNPEATLMNLTHNAI--DNL-LYAFNLYTQLTVLDISYNKILDLGSEN 88
C A LE+ P L L NLTH ++ +NL + NL + L L +SYN+I+ L E+
Sbjct: 184 CRQA-LEVAPGAL---LGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPED 239
Query: 89 FESNSEMRHLNLSNNFLK----------------RLDKDAFVGXXXXXXXXXXXXEISNI 132
+ + +R L++ N + +L D F +S +
Sbjct: 240 LANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWL 299
Query: 133 HVQTFRDLSALERLDFSNNRLVTFEPET--FEPLSSLKILSLRNNSILDIPSANL----- 185
+ FR L L LD S N L +T F+ L+ L+ L+L N + A+L
Sbjct: 300 NASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPS 359
Query: 186 -GFVIHLEYLDLSE---NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLG-FHSLPSLR 240
G ++ L+ LD+ + + + L L L+ L L N I QLG F + P LR
Sbjct: 360 FGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQA-QLGIFRAFPGLR 418
Query: 241 HLDLSDNNMT 250
++DLSDN ++
Sbjct: 419 YVDLSDNRIS 428
Score = 45.2 bits (102), Expect = 6e-04
Identities = 61/219 (27%), Positives = 93/219 (42%), Gaps = 15/219 (6%)
Query: 66 NLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKR-LDKDAFVGXXXXXXXXX 124
N T LD+S N ++ + E F S ++ L LS+N + + ++ F+
Sbjct: 469 NCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDL 528
Query: 125 XXXEISNIHVQTFRDLSALERLDFSNN------RLVTFEPETFEPLSSLKILSLRNNSIL 178
++ H +F +L LE LD S N + V L +L+ LSL +N+I
Sbjct: 529 SRNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIH 588
Query: 179 DIPSANLGFVIHLEYLDLSENLIQQVSRHG---LPF---LKELKHLDLNNNIIESVDQLG 232
S L L LD S N + + G L F L L LDL+ N + ++
Sbjct: 589 SQVSQQL-CSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQT 647
Query: 233 FHSLP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
+LP SL+ L L DN + +L L L L L+G
Sbjct: 648 LRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAG 686
Score = 37.1 bits (82), Expect = 0.17
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 154 VTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLK 213
+T EP TF + +L+ L+L N+I+ +P+ + L LS I + L L
Sbjct: 112 MTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLI----SLSLSHTNILMLDSASLAGLH 167
Query: 214 ELKHLDLNNNIIE--------SVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNL 263
L+ L ++ N V L +L HL L NN+T++P + S L L
Sbjct: 168 ALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYL 225
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 68.9 bits (161), Expect = 4e-11
Identities = 72/275 (26%), Positives = 119/275 (43%), Gaps = 13/275 (4%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L A AA+ V C D + SC L VP L P+ ++L+ N + +
Sbjct: 6 LLLLALLTLGLAAQHQDKVPCKMVD--KKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRS 63
Query: 61 LLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXX-- 117
+L + YT L LD+S N+I L F++ + + HL+L++N L + G
Sbjct: 64 ILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPL 123
Query: 118 --XXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
S + + + +L L + N L TF + +L+ L L +N
Sbjct: 124 PRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSN 183
Query: 176 SILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHS 235
++DI + L +L+LS N + +S L++L+ LDL+ N IE+
Sbjct: 184 VLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS---LQQLRVLDLSCNSIEAFQTASQPQ 240
Query: 236 LP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L LDL +N + P L+ L L +L LS
Sbjct: 241 AEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLS 273
Score = 66.9 bits (156), Expect = 2e-10
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 6/180 (3%)
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-- 249
E LDLS N ++ + L F L+HLDL+ N I + F +L L HL L+ N +
Sbjct: 52 ETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAM 111
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
T + L L ++ L LSG R+ F D
Sbjct: 112 ATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRD 171
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
L+++ ++ NV + ++ F G P+LT++ + N+L + S F + +L+ L++S N
Sbjct: 172 MPALEQLDLHSNV-LMDIEDGAFEGLPRLTHLNLSRNSLTCI--SDFSLQQLRVLDLSCN 228
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 163 PLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
PLS L L L N I IP + L + L +L+LS N ++ L L L LDL++
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 223 NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
N +E++ +LG +L SLR L L N + +P + L++L L L G
Sbjct: 373 NALETL-ELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQG 419
Score = 46.0 bits (104), Expect = 4e-04
Identities = 59/227 (25%), Positives = 94/227 (41%), Gaps = 21/227 (9%)
Query: 46 PEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
P L++L+HNA++ L L L + N + DL F + + ++ LNL N +
Sbjct: 363 PCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
G F +++L L +N + F +
Sbjct: 423 SPCGGPDEPGPSG---------------CVAFSGITSLRSLSLVDNEIELLRAGAFLH-T 466
Query: 166 SLKILSLRNNSILDIPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
L L L +N L++ + L G LE L L N + V + LP LK L+L N
Sbjct: 467 PLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGL-MVLQVDLPCFICLKRLNLAENR 525
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL-SNLSHLYLSG 270
+ + + SL LDL +N+ +L+P SA+ L ++L LYL G
Sbjct: 526 LSHLP--AWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQG 570
Score = 41.9 bits (94), Expect = 0.006
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 11/164 (6%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
+QL LD+SYN+I + E + + LNLS N L+ +
Sbjct: 315 SQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNA 374
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-------P 181
+ + + R L +L L N L P TF L+SL+ L+L+ N + P
Sbjct: 375 LETLELGA-RALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGP 433
Query: 182 SANLGF--VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
S + F + L L L +N I ++ R G L LDL++N
Sbjct: 434 SGCVAFSGITSLRSLSLVDNEI-ELLRAGAFLHTPLTELDLSSN 476
Score = 37.9 bits (84), Expect = 0.094
Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 14/140 (10%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI--LDIPSANL 185
EI I L++L L+ S N L TFE L L +L L +N++ L++ + L
Sbjct: 326 EIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARAL 385
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV---DQLG------FHSL 236
G L L L N ++ + + L L+ L+L N + D+ G F +
Sbjct: 386 G---SLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGI 442
Query: 237 PSLRHLDLSDNNMTLIPTSA 256
SLR L L DN + L+ A
Sbjct: 443 TSLRSLSLVDNEIELLRAGA 462
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 68.9 bits (161), Expect = 4e-11
Identities = 72/275 (26%), Positives = 119/275 (43%), Gaps = 13/275 (4%)
Query: 1 MVLFAWTWSAAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDN 60
++L A AA+ V C D + SC L VP L P+ ++L+ N + +
Sbjct: 6 LLLLALLTLGLAAQHQDKVPCKMVD--KKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRS 63
Query: 61 LLYA-FNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXX-- 117
+L + YT L LD+S N+I L F++ + + HL+L++N L + G
Sbjct: 64 ILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPL 123
Query: 118 --XXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
S + + + +L L + N L TF + +L+ L L +N
Sbjct: 124 PRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSN 183
Query: 176 SILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHS 235
++DI + L +L+LS N + +S L++L+ LDL+ N IE+
Sbjct: 184 VLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFS---LQQLRVLDLSCNSIEAFQTASQPQ 240
Query: 236 LP-SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L LDL +N + P L+ L L +L LS
Sbjct: 241 AEFQLTWLDLRENKLLHFPD--LAALPRLIYLNLS 273
Score = 66.9 bits (156), Expect = 2e-10
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 6/180 (3%)
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-- 249
E LDLS N ++ + L F L+HLDL+ N I + F +L L HL L+ N +
Sbjct: 52 ETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAM 111
Query: 250 -TLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVD 308
T + L L ++ L LSG R+ F D
Sbjct: 112 ATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRD 171
Query: 309 NINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
L+++ ++ NV + ++ F G P+LT++ + N+L + S F + +L+ L++S N
Sbjct: 172 MPALEQLDLHSNV-LMDIEDGAFEGLPRLTHLNLSRNSLTCI--SDFSLQQLRVLDLSCN 228
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 1/108 (0%)
Query: 163 PLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNN 222
PLS L L L N I IP + L + L +L+LS N ++ L L L LDL++
Sbjct: 313 PLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSH 372
Query: 223 NIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSG 270
N +E++ +LG +L SLR L L N + +P + L++L L L G
Sbjct: 373 NALETL-ELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQG 419
Score = 46.0 bits (104), Expect = 4e-04
Identities = 59/227 (25%), Positives = 94/227 (41%), Gaps = 21/227 (9%)
Query: 46 PEATLMNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFL 105
P L++L+HNA++ L L L + N + DL F + + ++ LNL N +
Sbjct: 363 PCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRV 422
Query: 106 KRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLS 165
G F +++L L +N + F +
Sbjct: 423 SPCGGPDEPGPSG---------------CVAFSGITSLRSLSLVDNEIELLRAGAFLH-T 466
Query: 166 SLKILSLRNNSILDIPSANL-GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
L L L +N L++ + L G LE L L N + V + LP LK L+L N
Sbjct: 467 PLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGL-MVLQVDLPCFICLKRLNLAENR 525
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL-SNLSHLYLSG 270
+ + + SL LDL +N+ +L+P SA+ L ++L LYL G
Sbjct: 526 LSHLP--AWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQG 570
Score = 41.9 bits (94), Expect = 0.006
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 11/164 (6%)
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
+QL LD+SYN+I + E + + LNLS N L+ +
Sbjct: 315 SQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNA 374
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDI-------P 181
+ + + R L +L L N L P TF L+SL+ L+L+ N + P
Sbjct: 375 LETLELGA-RALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGP 433
Query: 182 SANLGF--VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
S + F + L L L +N I ++ R G L LDL++N
Sbjct: 434 SGCVAFSGITSLRSLSLVDNEI-ELLRAGAFLHTPLTELDLSSN 476
Score = 37.9 bits (84), Expect = 0.094
Identities = 41/140 (29%), Positives = 62/140 (44%), Gaps = 14/140 (10%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI--LDIPSANL 185
EI I L++L L+ S N L TFE L L +L L +N++ L++ + L
Sbjct: 326 EIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARAL 385
Query: 186 GFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV---DQLG------FHSL 236
G L L L N ++ + + L L+ L+L N + D+ G F +
Sbjct: 386 G---SLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGI 442
Query: 237 PSLRHLDLSDNNMTLIPTSA 256
SLR L L DN + L+ A
Sbjct: 443 TSLRSLSLVDNEIELLRAGA 462
>AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens
cDNA FLJ23995 fis, clone HRC11525. ).
Length = 459
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/221 (26%), Positives = 99/221 (44%), Gaps = 5/221 (2%)
Query: 161 FEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDL 220
F+ L +LK L + +N ++ I ++ LE L L + + V L L+ L L L
Sbjct: 2 FQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHL 61
Query: 221 NNNIIESVDQLGFHSLPSLRHLDLSD-NNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXX 279
+ I ++ F L L+HL++ + ++P ++L L NL+ L ++
Sbjct: 62 KHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGL-NLTSLSVTNTNLSTVPFL 120
Query: 280 XXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTN 339
I++ F D I LQ++ + ++R + P F G L
Sbjct: 121 AFKHLVYLTHLNLSYNPIST-IEAGMFSDLIRLQELHIV-GAQLRTIEPHSFQGLRFLRV 178
Query: 340 IYMKNNALETLEASHFPIDR-LQELEISGNPFACNCSLLWL 379
+ + N LETLE + F R L+ L I+ NP AC+C LLW+
Sbjct: 179 LNVSQNLLETLEENVFSSPRALEVLSINNNPLACDCRLLWI 219
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 4/178 (2%)
Query: 26 ALRAASCANANLEIVPIQ-LNPEATL--MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKI 81
+L + NL VP + L+ +L ++L H I+N+ +YAF L L+I Y +
Sbjct: 31 SLEQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPL 90
Query: 82 LDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLS 141
LD+ N + L+++N L + AF IS I F DL
Sbjct: 91 LDMMPANSLYGLNLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLI 150
Query: 142 ALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSEN 199
L+ L +L T EP +F+ L L++L++ N + + LE L ++ N
Sbjct: 151 RLQELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNN 208
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 60 NLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXX 119
N LY NL T L+V + + + + L F+ + HLNLS N + ++ F
Sbjct: 97 NSLYGLNL-TSLSVTNTNLSTVPFLA---FKHLVYLTHLNLSYNPISTIEAGMFSDLIRL 152
Query: 120 XXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSI 177
++ I +F+ L L L+ S N L T E F +L++LS+ NN +
Sbjct: 153 QELHIVGAQLRTIEPHSFQGLRFLRVLNVSQNLLETLEENVFSSPRALEVLSINNNPL 210
Score = 38.7 bits (86), Expect = 0.054
Identities = 38/181 (20%), Positives = 71/181 (39%)
Query: 89 FESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
F+ ++ L + +N L + AF G ++ + + L +L L
Sbjct: 2 FQDLHNLKSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLISLHL 61
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+ + F+ L LK L + +LD+ AN + ++L L ++ + V
Sbjct: 62 KHLNINNMPVYAFKRLFHLKHLEIDYWPLLDMMPANSLYGLNLTSLSVTNTNLSTVPFLA 121
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
L L HL+L+ N I +++ F L L+ L + + I + L L L +
Sbjct: 122 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 181
Query: 269 S 269
S
Sbjct: 182 S 182
>AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens
cDNA FLJ33057 fis, clone TRACH1000144, weakly similar to
CHONDROADHERIN PRECURSOR. ).
Length = 469
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 11/200 (5%)
Query: 216 KHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXX 275
K L +N N I+ VD F L L L N +T+I L+NL LYL+G
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 276 XXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNP 335
E I + F NLQ +++N+N+ ++ +P +F G P
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKE-ISAGTFDSMPNLQLLYLNNNL-LKSLPVYIFSGAP 129
Query: 336 KLTNIYMKNNALETLEASHFPIDRLQ---ELEISGNPFACNCSL----LWLWKLGKDSET 388
L + ++NN L S +D+LQ ++++ GNP+ C C L LW+ KL
Sbjct: 130 -LARLNLRNNKFMYLPVSGV-LDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVV 187
Query: 389 TTKKSGNSSEFLKIDYEDVK 408
K +F I+ + +K
Sbjct: 188 KELKCETPVQFANIELKSLK 207
Score = 66.5 bits (155), Expect = 2e-10
Identities = 42/143 (29%), Positives = 73/143 (51%), Gaps = 2/143 (1%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFV 188
I ++ V F D L+ L +N++ + + F L++L+ L L N I + +
Sbjct: 21 IKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGL 80
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
+L+YL L NLI+++S + L+ L LNNN+++S+ F P L L+L +N
Sbjct: 81 HNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAP-LARLNLRNNK 139
Query: 249 MTLIPTS-ALSKLSNLSHLYLSG 270
+P S L +L +L+ + L G
Sbjct: 140 FMYLPVSGVLDQLQSLTQIDLEG 162
Score = 41.1 bits (92), Expect = 0.010
Identities = 35/151 (23%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L ++ N I D+ +F + L+L +N + + D F +I ++
Sbjct: 14 LHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLY 73
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEY 193
+ F L L+ L N + TF+ + +L++L L NN + +P + L
Sbjct: 74 PEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLP-VYIFSGAPLAR 132
Query: 194 LDLSENLIQQVSRHG-LPFLKELKHLDLNNN 223
L+L N + G L L+ L +DL N
Sbjct: 133 LNLRNNKFMYLPVSGVLDQLQSLTQIDLEGN 163
Score = 40.7 bits (91), Expect = 0.013
Identities = 29/115 (25%), Positives = 54/115 (46%)
Query: 144 ERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQ 203
++L + N + + F L +L L +N I I + +L L L+ N I++
Sbjct: 12 KKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIER 71
Query: 204 VSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
+ L L++L L N+I+ + F S+P+L+ L L++N + +P S
Sbjct: 72 LYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSLPVYIFS 126
Score = 35.5 bits (78), Expect = 0.50
Identities = 24/80 (30%), Positives = 39/80 (48%)
Query: 189 IHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNN 248
++ + L ++ N I+ V + L L L +N I + FH+L +LR L L+ N
Sbjct: 9 LNAKKLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQ 68
Query: 249 MTLIPTSALSKLSNLSHLYL 268
+ + S L NL +LYL
Sbjct: 69 IERLYPEIFSGLHNLQYLYL 88
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 289 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 348
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 349 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 407
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 408 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 465
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 466 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 501
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 LEIVPIQLNPEATLMNL--THNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSE 94
L+ +P ++ LM L + N++ +L + + +L +LD+ +NK+ ++ S + +S
Sbjct: 135 LQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS- 193
Query: 95 MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLV 154
+ L L N + ++KD +I + + +L L LD ++N+L
Sbjct: 194 LTTLYLRFNRITTVEKD-IKNLSKLSMLSIRENKIKQLPAE-IGELCNLITLDVAHNQLE 251
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
P+ + + L L++N +LD+P +G + L L L N + + R L
Sbjct: 252 HL-PKEIGNCTQITNLDLQHNELLDLPD-TIGNLSSLSRLGLRYNRLSAIPR-SLAKCSA 308
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L+ L+L NN I ++ + SL L L L+ N L P S+ S + L
Sbjct: 309 LEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Score = 48.0 bits (109), Expect = 9e-05
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 26/241 (10%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSE--NFESNSE-------------- 94
+++ HN +++L TQ+T LD+ +N++LDL N S S
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRS 302
Query: 95 ------MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
+ LNL NN + L + V S + L+
Sbjct: 303 LAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNM 362
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+NR+ F L L++++N + +P + G + L+L+ N + ++
Sbjct: 363 EHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIP-ED 420
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L L+ L L+NN+++ + G +L LR LDL +N + +P + ++ L +L L L
Sbjct: 421 VSGLVSLEVLILSNNLLKKLPH-GLGNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVL 478
Query: 269 S 269
+
Sbjct: 479 T 479
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 311 NLQKIWMND--NVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
NL+K+ M D + K+RE+P ++ + LT +Y++ N + T+E + +L L I N
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN 225
Query: 369 -----PFACN--CSLLWLWKLGKDSETTTKKSGNSSEFLKIDYE 405
P C+L+ L E K+ GN ++ +D +
Sbjct: 226 KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQ 269
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 79 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 138
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 139 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 197
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 198 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 255
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 256 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 291
Score = 37.1 bits (82), Expect = 0.17
Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 164 LSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNN 223
L L++L LR+N + +IPS + + L L L N I V + + L +L L + N
Sbjct: 4 LKKLRMLDLRHNKLREIPSV-VYRLDSLTTLYLRFNRITTVEK-DIKNLSKLSMLSIREN 61
Query: 224 IIESVD-QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
I+ + ++G +L SL L L N ++ IP S L+K S L L L
Sbjct: 62 KIKQLPAEIG--NLSSLSRLGLRYNRLSAIPRS-LAKCSALEELNL 104
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 289 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 348
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 349 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 407
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 408 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 465
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 466 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 501
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 LEIVPIQLNPEATLMNL--THNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSE 94
L+ +P ++ LM L + N++ +L + + +L +LD+ +NK+ ++ S + +S
Sbjct: 135 LQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS- 193
Query: 95 MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLV 154
+ L L N + ++KD +I + + +L L LD ++N+L
Sbjct: 194 LTTLYLRFNRITTVEKD-IKNLSKLSMLSIRENKIKQLPAE-IGELCNLITLDVAHNQLE 251
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
P+ + + L L++N +LD+P +G + L L L N + + R L
Sbjct: 252 HL-PKEIGNCTQITNLDLQHNELLDLPD-TIGNLSSLSRLGLRYNRLSAIPR-SLAKCSA 308
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L+ L+L NN I ++ + SL L L L+ N L P S+ S + L
Sbjct: 309 LEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Score = 48.0 bits (109), Expect = 9e-05
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 26/241 (10%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSE--NFESNSE-------------- 94
+++ HN +++L TQ+T LD+ +N++LDL N S S
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRS 302
Query: 95 ------MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
+ LNL NN + L + V S + L+
Sbjct: 303 LAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNM 362
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+NR+ F L L++++N + +P + G + L+L+ N + ++
Sbjct: 363 EHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIP-ED 420
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L L+ L L+NN+++ + G +L LR LDL +N + +P + ++ L +L L L
Sbjct: 421 VSGLVSLEVLILSNNLLKKLPH-GLGNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVL 478
Query: 269 S 269
+
Sbjct: 479 T 479
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 311 NLQKIWMND--NVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
NL+K+ M D + K+RE+P ++ + LT +Y++ N + T+E + +L L I N
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN 225
Query: 369 -----PFACN--CSLLWLWKLGKDSETTTKKSGNSSEFLKIDYE 405
P C+L+ L E K+ GN ++ +D +
Sbjct: 226 KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQ 269
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 289 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 348
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 349 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 407
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 408 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 465
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 466 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 501
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 LEIVPIQLNPEATLMNL--THNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSE 94
L+ +P ++ LM L + N++ +L + + +L +LD+ +NK+ ++ S + +S
Sbjct: 135 LQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS- 193
Query: 95 MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLV 154
+ L L N + ++KD +I + + +L L LD ++N+L
Sbjct: 194 LTTLYLRFNRITTVEKD-IKNLSKLSMLSIRENKIKQLPAE-IGELCNLITLDVAHNQLE 251
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
P+ + + L L++N +LD+P +G + L L L N + + R L
Sbjct: 252 HL-PKEIGNCTQITNLDLQHNELLDLPD-TIGNLSSLSRLGLRYNRLSAIPR-SLAKCSA 308
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L+ L+L NN I ++ + SL L L L+ N L P S+ S + L
Sbjct: 309 LEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Score = 48.0 bits (109), Expect = 9e-05
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 26/241 (10%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSE--NFESNSE-------------- 94
+++ HN +++L TQ+T LD+ +N++LDL N S S
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRS 302
Query: 95 ------MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
+ LNL NN + L + V S + L+
Sbjct: 303 LAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNM 362
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+NR+ F L L++++N + +P + G + L+L+ N + ++
Sbjct: 363 EHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIP-ED 420
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L L+ L L+NN+++ + G +L LR LDL +N + +P + ++ L +L L L
Sbjct: 421 VSGLVSLEVLILSNNLLKKLPH-GLGNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVL 478
Query: 269 S 269
+
Sbjct: 479 T 479
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 311 NLQKIWMND--NVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
NL+K+ M D + K+RE+P ++ + LT +Y++ N + T+E + +L L I N
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN 225
Query: 369 -----PFACN--CSLLWLWKLGKDSETTTKKSGNSSEFLKIDYE 405
P C+L+ L E K+ GN ++ +D +
Sbjct: 226 KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQ 269
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 289 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 348
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 349 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 407
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 408 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 465
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 466 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 501
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 LEIVPIQLNPEATLMNL--THNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSE 94
L+ +P ++ LM L + N++ +L + + +L +LD+ +NK+ ++ S + +S
Sbjct: 135 LQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS- 193
Query: 95 MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLV 154
+ L L N + ++KD +I + + +L L LD ++N+L
Sbjct: 194 LTTLYLRFNRITTVEKD-IKNLSKLSMLSIRENKIKQLPAE-IGELCNLITLDVAHNQLE 251
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
P+ + + L L++N +LD+P +G + L L L N + + R L
Sbjct: 252 HL-PKEIGNCTQITNLDLQHNELLDLPD-TIGNLSSLSRLGLRYNRLSAIPR-SLAKCSA 308
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L+ L+L NN I ++ + SL L L L+ N L P S+ S + L
Sbjct: 309 LEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 360
Score = 48.0 bits (109), Expect = 9e-05
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 26/241 (10%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSE--NFESNSE-------------- 94
+++ HN +++L TQ+T LD+ +N++LDL N S S
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRS 302
Query: 95 ------MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
+ LNL NN + L + V S + L+
Sbjct: 303 LAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNM 362
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+NR+ F L L++++N + +P + G + L+L+ N + ++
Sbjct: 363 EHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIP-ED 420
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L L+ L L+NN+++ + G +L LR LDL +N + +P + ++ L +L L L
Sbjct: 421 VSGLVSLEVLILSNNLLKKLPH-GLGNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVL 478
Query: 269 S 269
+
Sbjct: 479 T 479
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 311 NLQKIWMND--NVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
NL+K+ M D + K+RE+P ++ + LT +Y++ N + T+E + +L L I N
Sbjct: 167 NLKKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN 225
Query: 369 -----PFACN--CSLLWLWKLGKDSETTTKKSGNSSEFLKIDYE 405
P C+L+ L E K+ GN ++ +D +
Sbjct: 226 KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQ 269
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 68.1 bits (159), Expect = 8e-11
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 7/219 (3%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDK 110
+ L +N + + + + L L++ N I L S ++ L L+ N +
Sbjct: 291 LGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPV 350
Query: 111 DAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKIL 170
I+ I F L +L+ +N+L + P F +S+ L
Sbjct: 351 GGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSL-PLDFGTWTSMVEL 409
Query: 171 SLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV-D 229
+L N + IP G V LE L LS NL++++ HGL L++L+ LDL N +ES+ +
Sbjct: 410 NLATNQLTKIPEDVSGLV-SLEVLILSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPN 467
Query: 230 QLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
++ + L L+ L L++N +T +P + L+NL+HL L
Sbjct: 468 EIAY--LKDLQKLVLTNNQLTTLP-RGIGHLTNLTHLGL 503
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/232 (24%), Positives = 106/232 (45%), Gaps = 8/232 (3%)
Query: 37 LEIVPIQLNPEATLMNL--THNAIDNLLYAFNLYTQLTVLDISYNKILDLGSENFESNSE 94
L+ +P ++ LM L + N++ +L + + +L +LD+ +NK+ ++ S + +S
Sbjct: 137 LQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDS- 195
Query: 95 MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLV 154
+ L L N + ++KD +I + + +L L LD ++N+L
Sbjct: 196 LTTLYLRFNRITTVEKD-IKNLSKLSMLSIRENKIKQLPAE-IGELCNLITLDVAHNQLE 253
Query: 155 TFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKE 214
P+ + + L L++N +LD+P +G + L L L N + + R L
Sbjct: 254 HL-PKEIGNCTQITNLDLQHNELLDLPD-TIGNLSSLSRLGLRYNRLSAIPR-SLAKCSA 310
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L+ L+L NN I ++ + SL L L L+ N L P S+ S + L
Sbjct: 311 LEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSL 362
Score = 48.0 bits (109), Expect = 9e-05
Identities = 54/241 (22%), Positives = 101/241 (41%), Gaps = 26/241 (10%)
Query: 51 MNLTHNAIDNLLYAFNLYTQLTVLDISYNKILDLGSE--NFESNSE-------------- 94
+++ HN +++L TQ+T LD+ +N++LDL N S S
Sbjct: 245 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRS 304
Query: 95 ------MRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDF 148
+ LNL NN + L + V S + L+
Sbjct: 305 LAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNM 364
Query: 149 SNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHG 208
+NR+ F L L++++N + +P + G + L+L+ N + ++
Sbjct: 365 EHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIP-ED 422
Query: 209 LPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ L L+ L L+NN+++ + G +L LR LDL +N + +P + ++ L +L L L
Sbjct: 423 VSGLVSLEVLILSNNLLKKLPH-GLGNLRKLRELDLEENKLESLP-NEIAYLKDLQKLVL 480
Query: 269 S 269
+
Sbjct: 481 T 481
Score = 31.9 bits (69), Expect = 6.2
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 10/104 (9%)
Query: 311 NLQKIWMND--NVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFPIDRLQELEISGN 368
NL+K+ M D + K+RE+P ++ + LT +Y++ N + T+E + +L L I N
Sbjct: 169 NLKKLRMLDLRHNKLREIPSVVYRLD-SLTTLYLRFNRITTVEKDIKNLSKLSMLSIREN 227
Query: 369 -----PFACN--CSLLWLWKLGKDSETTTKKSGNSSEFLKIDYE 405
P C+L+ L E K+ GN ++ +D +
Sbjct: 228 KIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQ 271
>BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for
IMAGE:5468269) protein.
Length = 460
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/134 (29%), Positives = 72/134 (53%), Gaps = 1/134 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
FR+++ L L S N + F L SL+ L L N ++++ + +L ++L++L L
Sbjct: 68 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 127
Query: 197 SENLIQQVSRHGLP-FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
S N + +++ FL+ L+ LDL+ N + V G ++P+L L+L N + +P
Sbjct: 128 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 187
Query: 256 ALSKLSNLSHLYLS 269
A ++L LS L L+
Sbjct: 188 AFAQLGQLSRLDLT 201
Score = 67.3 bits (157), Expect = 1e-10
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF++ L F I+ I + F DL +L L NRLV
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+ +L+ L L N + I P A F+ LE LDLS N ++QV G+ + L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-TLIPTSALSK 259
L+L++N+I+++ F L L LDL+ N + TL P S+
Sbjct: 173 TLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSR 216
Score = 65.3 bits (152), Expect = 5e-10
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 37/317 (11%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N IQ + + L L L+ N I + F L SLR L L N + +
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
T +L NL HL LSG ++ L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASH-FPIDRLQE-------LEI 365
+ ++ N+ + +PP F +L+ + + +N L TL F R E L
Sbjct: 173 TLNLDHNL-IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSF 231
Query: 366 SGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPE 425
SGNP CNC LLWL +L + + T C+ P L G F +PE
Sbjct: 232 SGNPLHCNCELLWLRRLARPDDLET------------------CASPPGLAGRYFWAVPE 273
Query: 426 SEFGCSSG---------WVIDAXXXXXXXXXXXXXCAVLYFMGPLKKCKGDKSK-QIMTS 475
EF C WV++ ++++GP + G+ S+ + +
Sbjct: 274 GEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPN 333
Query: 476 VMMNGDVSKLGNGLGYS 492
+ V+ G+ GY+
Sbjct: 334 GTLEIGVTGAGDAGGYT 350
Score = 59.3 bits (137), Expect = 4e-08
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 4/193 (2%)
Query: 11 AAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
A+ CP+ C+C + + S CA+ L VP ++ + L N I L F
Sbjct: 11 ASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRN 70
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
T L L +S N I +G+ F +R L+L N L L + G
Sbjct: 71 MTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGN 130
Query: 128 EISNIHVQTFRD-LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F D L +LE LD S N L + +L L+L +N I +P
Sbjct: 131 QLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFA 190
Query: 187 FVIHLEYLDLSEN 199
+ L LDL+ N
Sbjct: 191 QLGQLSRLDLTSN 203
Score = 37.9 bits (84), Expect = 0.094
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ NAI + AF L L + N++++LG+ + ++HL LS N L R+
Sbjct: 77 LTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIA 136
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF + + + AL L+ +N + P F L L
Sbjct: 137 PGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLS 196
Query: 169 ILSLRNNSI 177
L L +N +
Sbjct: 197 RLDLTSNRL 205
>BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 4 protein.
Length = 635
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/134 (29%), Positives = 72/134 (53%), Gaps = 1/134 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
FR+++ L L S N + F L SL+ L L N ++++ + +L ++L++L L
Sbjct: 68 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 127
Query: 197 SENLIQQVSRHGLP-FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
S N + +++ FL+ L+ LDL+ N + V G ++P+L L+L N + +P
Sbjct: 128 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 187
Query: 256 ALSKLSNLSHLYLS 269
A ++L LS L L+
Sbjct: 188 AFAQLGQLSRLDLT 201
Score = 67.3 bits (157), Expect = 1e-10
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF++ L F I+ I + F DL +L L NRLV
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+ +L+ L L N + I P A F+ LE LDLS N ++QV G+ + L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-TLIPTSALSK 259
L+L++N+I+++ F L L LDL+ N + TL P S+
Sbjct: 173 TLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSR 216
Score = 65.3 bits (152), Expect = 5e-10
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 37/317 (11%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N IQ + + L L L+ N I + F L SLR L L N + +
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
T +L NL HL LSG ++ L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASH-FPIDRLQE-------LEI 365
+ ++ N+ + +PP F +L+ + + +N L TL F R E L
Sbjct: 173 TLNLDHNL-IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSF 231
Query: 366 SGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPE 425
SGNP CNC LLWL +L + + T C+ P L G F +PE
Sbjct: 232 SGNPLHCNCELLWLRRLARPDDLET------------------CASPPGLAGRYFWAVPE 273
Query: 426 SEFGCSSG---------WVIDAXXXXXXXXXXXXXCAVLYFMGPLKKCKGDKSK-QIMTS 475
EF C WV++ ++++GP + G+ S+ + +
Sbjct: 274 GEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPN 333
Query: 476 VMMNGDVSKLGNGLGYS 492
+ V+ G+ GY+
Sbjct: 334 GTLEIGVTGAGDAGGYT 350
Score = 59.3 bits (137), Expect = 4e-08
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 4/193 (2%)
Query: 11 AAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
A+ CP+ C+C + + S CA+ L VP ++ + L N I L F
Sbjct: 11 ASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRN 70
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
T L L +S N I +G+ F +R L+L N L L + G
Sbjct: 71 MTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGN 130
Query: 128 EISNIHVQTFRD-LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F D L +LE LD S N L + +L L+L +N I +P
Sbjct: 131 QLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFA 190
Query: 187 FVIHLEYLDLSEN 199
+ L LDL+ N
Sbjct: 191 QLGQLSRLDLTSN 203
Score = 37.9 bits (84), Expect = 0.094
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ NAI + AF L L + N++++LG+ + ++HL LS N L R+
Sbjct: 77 LTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIA 136
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF + + + AL L+ +N + P F L L
Sbjct: 137 PGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLS 196
Query: 169 ILSLRNNSI 177
L L +N +
Sbjct: 197 RLDLTSNRL 205
>BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein.
Length = 541
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/134 (29%), Positives = 72/134 (53%), Gaps = 1/134 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
FR+++ L L S N + F L SL+ L L N ++++ + +L ++L++L L
Sbjct: 68 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 127
Query: 197 SENLIQQVSRHGLP-FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
S N + +++ FL+ L+ LDL+ N + V G ++P+L L+L N + +P
Sbjct: 128 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 187
Query: 256 ALSKLSNLSHLYLS 269
A ++L LS L L+
Sbjct: 188 AFAQLGQLSRLDLT 201
Score = 67.3 bits (157), Expect = 1e-10
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF++ L F I+ I + F DL +L L NRLV
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+ +L+ L L N + I P A F+ LE LDLS N ++QV G+ + L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-TLIPTSALSK 259
L+L++N+I+++ F L L LDL+ N + TL P S+
Sbjct: 173 TLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSR 216
Score = 65.3 bits (152), Expect = 5e-10
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 37/317 (11%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N IQ + + L L L+ N I + F L SLR L L N + +
Sbjct: 53 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 112
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
T +L NL HL LSG ++ L
Sbjct: 113 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 172
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASH-FPIDRLQE-------LEI 365
+ ++ N+ + +PP F +L+ + + +N L TL F R E L
Sbjct: 173 TLNLDHNL-IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSF 231
Query: 366 SGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPE 425
SGNP CNC LLWL +L + + T C+ P L G F +PE
Sbjct: 232 SGNPLHCNCELLWLRRLARPDDLET------------------CASPPGLAGRYFWAVPE 273
Query: 426 SEFGCSSG---------WVIDAXXXXXXXXXXXXXCAVLYFMGPLKKCKGDKSK-QIMTS 475
EF C WV++ ++++GP + G+ S+ + +
Sbjct: 274 GEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSRARAFPN 333
Query: 476 VMMNGDVSKLGNGLGYS 492
+ V+ G+ GY+
Sbjct: 334 GTLEIGVTGAGDAGGYT 350
Score = 59.3 bits (137), Expect = 4e-08
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 4/193 (2%)
Query: 11 AAAKTLCPVRCMCDDALRAAS--CANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNL 67
A+ CP+ C+C + + S CA+ L VP ++ + L N I L F
Sbjct: 11 ASGAAACPLPCVCQNLSESLSTLCAHRGLLFVPPNVDRRTVELRLADNFIQALGPPDFRN 70
Query: 68 YTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXX 127
T L L +S N I +G+ F +R L+L N L L + G
Sbjct: 71 MTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGN 130
Query: 128 EISNIHVQTFRD-LSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
++ I F D L +LE LD S N L + +L L+L +N I +P
Sbjct: 131 QLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFA 190
Query: 187 FVIHLEYLDLSEN 199
+ L LDL+ N
Sbjct: 191 QLGQLSRLDLTSN 203
Score = 37.9 bits (84), Expect = 0.094
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ NAI + AF L L + N++++LG+ + ++HL LS N L R+
Sbjct: 77 LTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIA 136
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF + + + AL L+ +N + P F L L
Sbjct: 137 PGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLS 196
Query: 169 ILSLRNNSI 177
L L +N +
Sbjct: 197 RLDLTSNRL 205
>AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein.
Length = 789
Score = 67.7 bits (158), Expect = 1e-10
Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 1/170 (0%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L NF+ + + F IS+I +F DL +L L +NRL +
Sbjct: 57 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 116
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+T L +L+ L + NN + I A F++ LE LDLS N + + + + L
Sbjct: 117 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 176
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L L++N+++ + + F L L LDL+ N + +P + S S L
Sbjct: 177 QLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASAL 226
Score = 57.2 bits (132), Expect = 1e-07
Identities = 56/235 (23%), Positives = 85/235 (36%), Gaps = 16/235 (6%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N I +SR + L L L+ N I + F L SLR L L N + +
Sbjct: 57 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 116
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
L L NL HL ++ + + +NL
Sbjct: 117 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 176
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL---------EASHF---PIDRLQ 361
++ ++ N+ + + F KL + + +N L+ L +AS P
Sbjct: 177 QLSLDHNL-LDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPL 235
Query: 362 ELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSE---FLKIDYEDVKCSGPL 413
GNP CNC LLWL +L +D + T S + F + E+ C PL
Sbjct: 236 SFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPL 290
Score = 56.4 bits (130), Expect = 3e-07
Identities = 37/156 (23%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + N I+ + ++F + + + L LS N + + +F+ + ++
Sbjct: 57 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 116
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEP-LSSLKILSLRNNSILDIPSANLGFVIHLE 192
T R L L+ L +NN+L E FE L +L+ L L N++ +P ++ +++L
Sbjct: 117 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 176
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L NL+ ++ L++L LDL +N ++ +
Sbjct: 177 QLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKL 212
Score = 35.5 bits (78), Expect = 0.50
Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ N I ++ ++F L L + N++ LG + ++HL ++NN L +
Sbjct: 81 LTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIA 140
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+AF + + + R + L +L +N L TF L L
Sbjct: 141 DEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLA 200
Query: 169 ILSLRNNSILDIP 181
L L +N + +P
Sbjct: 201 RLDLTSNRLQKLP 213
>AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and
fibronectin type III domain containing 4 variant
protein.
Length = 622
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/134 (29%), Positives = 72/134 (53%), Gaps = 1/134 (0%)
Query: 137 FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDL 196
FR+++ L L S N + F L SL+ L L N ++++ + +L ++L++L L
Sbjct: 55 FRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLIL 114
Query: 197 SENLIQQVSRHGLP-FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTS 255
S N + +++ FL+ L+ LDL+ N + V G ++P+L L+L N + +P
Sbjct: 115 SGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPG 174
Query: 256 ALSKLSNLSHLYLS 269
A ++L LS L L+
Sbjct: 175 AFAQLGQLSRLDLT 188
Score = 67.3 bits (157), Expect = 1e-10
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L++NF++ L F I+ I + F DL +L L NRLV
Sbjct: 40 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 99
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+ +L+ L L N + I P A F+ LE LDLS N ++QV G+ + L
Sbjct: 100 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 159
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNM-TLIPTSALSK 259
L+L++N+I+++ F L L LDL+ N + TL P S+
Sbjct: 160 TLNLDHNLIDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSR 203
Score = 64.9 bits (151), Expect = 7e-10
Identities = 70/294 (23%), Positives = 106/294 (36%), Gaps = 36/294 (12%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L++N IQ + + L L L+ N I + F L SLR L L N + +
Sbjct: 40 LRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELG 99
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
T +L NL HL LSG ++ L
Sbjct: 100 TGSLRGPVNLQHLILSGNQLGRIAPGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALH 159
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASH-FPIDRLQE-------LEI 365
+ ++ N+ + +PP F +L+ + + +N L TL F R E L
Sbjct: 160 TLNLDHNL-IDALPPGAFAQLGQLSRLDLTSNRLATLAPDPLFSRGRDAEASPAPLVLSF 218
Query: 366 SGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQIPE 425
SGNP CNC LLWL +L + + T C+ P L G F +PE
Sbjct: 219 SGNPLHCNCELLWLRRLARPDDLET------------------CASPPGLAGRYFWAVPE 260
Query: 426 SEFGCSSG---------WVIDAXXXXXXXXXXXXXCAVLYFMGPLKKCKGDKSK 470
EF C WV++ ++++GP + G+ S+
Sbjct: 261 GEFSCEPPLIARHTQRLWVLEGQRATLRCRALGDPAPTMHWVGPDDRLVGNSSR 314
Score = 37.9 bits (84), Expect = 0.094
Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 2/129 (1%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ NAI + AF L L + N++++LG+ + ++HL LS N L R+
Sbjct: 64 LTLSRNAITRIGARAFGDLESLRSLHLDGNRLVELGTGSLRGPVNLQHLILSGNQLGRIA 123
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
AF + + + AL L+ +N + P F L L
Sbjct: 124 PGAFDDFLESLEDLDLSYNNLRQVPWAGIGAMPALHTLNLDHNLIDALPPGAFAQLGQLS 183
Query: 169 ILSLRNNSI 177
L L +N +
Sbjct: 184 RLDLTSNRL 192
>AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein.
Length = 832
Score = 67.7 bits (158), Expect = 1e-10
Identities = 47/170 (27%), Positives = 77/170 (45%), Gaps = 1/170 (0%)
Query: 98 LNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFE 157
L L NF+ + + F IS+I +F DL +L L +NRL +
Sbjct: 100 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 159
Query: 158 PETFEPLSSLKILSLRNNSILDI-PSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELK 216
+T L +L+ L + NN + I A F++ LE LDLS N + + + + L
Sbjct: 160 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 219
Query: 217 HLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHL 266
L L++N+++ + + F L L LDL+ N + +P + S S L
Sbjct: 220 QLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASAL 269
Score = 57.2 bits (132), Expect = 1e-07
Identities = 56/235 (23%), Positives = 85/235 (36%), Gaps = 16/235 (6%)
Query: 194 LDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIP 253
L L N I +SR + L L L+ N I + F L SLR L L N + +
Sbjct: 100 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 159
Query: 254 TSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDSRAFVDNINLQ 313
L L NL HL ++ + + +NL
Sbjct: 160 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 219
Query: 314 KIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETL---------EASHF---PIDRLQ 361
++ ++ N+ + + F KL + + +N L+ L +AS P
Sbjct: 220 QLSLDHNL-LDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPL 278
Query: 362 ELEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSE---FLKIDYEDVKCSGPL 413
GNP CNC LLWL +L +D + T S + F + E+ C PL
Sbjct: 279 SFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPL 333
Score = 56.4 bits (130), Expect = 3e-07
Identities = 37/156 (23%), Positives = 74/156 (47%), Gaps = 1/156 (0%)
Query: 74 LDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIH 133
L + N I+ + ++F + + + L LS N + + +F+ + ++
Sbjct: 100 LRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLG 159
Query: 134 VQTFRDLSALERLDFSNNRLVTFEPETFEP-LSSLKILSLRNNSILDIPSANLGFVIHLE 192
T R L L+ L +NN+L E FE L +L+ L L N++ +P ++ +++L
Sbjct: 160 EDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLH 219
Query: 193 YLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESV 228
L L NL+ ++ L++L LDL +N ++ +
Sbjct: 220 QLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKL 255
Score = 35.5 bits (78), Expect = 0.50
Identities = 29/133 (21%), Positives = 54/133 (40%), Gaps = 2/133 (1%)
Query: 51 MNLTHNAIDNLL-YAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
+ L+ N I ++ ++F L L + N++ LG + ++HL ++NN L +
Sbjct: 124 LTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIA 183
Query: 110 KDAFVG-XXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLK 168
+AF + + + R + L +L +N L TF L L
Sbjct: 184 DEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLA 243
Query: 169 ILSLRNNSILDIP 181
L L +N + +P
Sbjct: 244 RLDLTSNRLQKLP 256
>AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens
cDNA FLJ38291 fis, clone FCBBF3009069, weakly similar to
Homo sapiens HT017 mRNA. ).
Length = 370
Score = 67.3 bits (157), Expect = 1e-10
Identities = 46/167 (27%), Positives = 71/167 (42%), Gaps = 1/167 (0%)
Query: 10 AAAAKTLCPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNL-LYAFNLY 68
A A CP C CD C+ L VP + + L +N + L +AF
Sbjct: 32 AVEALPTCPFSCKCDSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANL 91
Query: 69 TQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXE 128
+ L LD+S N + L F + + L L NN ++ LD+D
Sbjct: 92 SSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSING 151
Query: 129 ISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNN 175
++ + F L AL L +NRL + TFEPL++L++L + +N
Sbjct: 152 LAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDN 198
Score = 64.9 bits (151), Expect = 7e-10
Identities = 43/120 (35%), Positives = 65/120 (54%)
Query: 128 EISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGF 187
++S + F +LS+L+RLD SNN L F L++L L LRNNSI + L
Sbjct: 79 KLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRH 138
Query: 188 VIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
L +LDLS N + Q+ L L+ L L +N ++++D+L F L +L+ L + DN
Sbjct: 139 SPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDN 198
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/130 (33%), Positives = 62/130 (47%), Gaps = 4/130 (3%)
Query: 139 DLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSE 198
D +LE +D S L T P+ P ++ +L L NN + +PS + L+ LDLS
Sbjct: 46 DSRSLE-VDCSGLGLTTVPPDV--PAATRTLLLL-NNKLSALPSWAFANLSSLQRLDLSN 101
Query: 199 NLIQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALS 258
N + ++ R L L L L NN I ++D+ P LRHLDLS N + +P
Sbjct: 102 NFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFD 161
Query: 259 KLSNLSHLYL 268
L L L L
Sbjct: 162 GLLALRSLSL 171
Score = 53.6 bits (123), Expect = 2e-06
Identities = 40/126 (31%), Positives = 58/126 (46%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
+A L NN+L F LSSL+ L L NN + +P + G + +L L L N
Sbjct: 68 AATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNS 127
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKL 260
I+ + R L L+HLDL+ N + + F L +LR L L N + + L
Sbjct: 128 IRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPL 187
Query: 261 SNLSHL 266
+NL L
Sbjct: 188 ANLQLL 193
Score = 44.0 bits (99), Expect = 0.001
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 3/138 (2%)
Query: 240 RHLDLSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXE 299
R L L +N ++ +P+ A + LS+L L LS
Sbjct: 71 RTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI-R 129
Query: 300 RIDSRAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHF-PID 358
+D + L+ + ++ N + ++PP LF G L ++ +++N L+ L+ F P+
Sbjct: 130 TLDRDLLRHSPLLRHLDLSIN-GLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLA 188
Query: 359 RLQELEISGNPFACNCSL 376
LQ L++ NP+ C+C+L
Sbjct: 189 NLQLLQVGDNPWECDCNL 206
Score = 40.3 bits (90), Expect = 0.018
Identities = 32/128 (25%), Positives = 48/128 (37%)
Query: 96 RHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVT 155
R L L NN L L AF + + F DL+ L L NN + T
Sbjct: 71 RTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRT 130
Query: 156 FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKEL 215
+ + L+ L L N + +P ++ L L L N +Q + R L L
Sbjct: 131 LDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANL 190
Query: 216 KHLDLNNN 223
+ L + +N
Sbjct: 191 QLLQVGDN 198
Score = 33.9 bits (74), Expect = 1.5
Identities = 19/58 (32%), Positives = 30/58 (51%)
Query: 212 LKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
L L+ LDL+NN ++ + + F L +L L L +N++ + L L HL LS
Sbjct: 91 LSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLS 148
>BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein.
Length = 858
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/224 (30%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L+H + +L F L VL+++YNKI + E F ++ LNLS N L L
Sbjct: 293 LDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELY 352
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
F G I+ I QTF+ L L+ LD +N L T F P S+
Sbjct: 353 SSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH---FIP--SIPD 407
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD---LNNNIIE 226
+ L N ++ +P NL + LSEN ++ + L FL + HL LN N
Sbjct: 408 IFLSGNKLVTLPKINL----TANLIHLSENRLENLDI--LYFLLRVPHLQILILNQNRFS 461
Query: 227 SV--DQLGFHSLPSLRHLDLSDNNMTLIPTSAL--SKLSNLSHL 266
S DQ + PSL L L +N + L + L LSHL
Sbjct: 462 SCSGDQTPSEN-PSLEQLFLGENMLQLAWETELCWDVFEGLSHL 504
Score = 56.8 bits (131), Expect = 2e-07
Identities = 35/112 (31%), Positives = 56/112 (50%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
S++ LD S+ + + FE L LK+L+L N I I + +L+ L+LS NL
Sbjct: 288 SSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNL 347
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
+ ++ L ++ ++DL N I + F L L+ LDL DN +T I
Sbjct: 348 LGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTI 399
Score = 44.4 bits (100), Expect = 0.001
Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 6/147 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDI-SYNKILDLGSENFESNS 93
NL VP LN L+ L+ N I + + F QL +L++ S L + E F +
Sbjct: 37 NLTQVPQVLNTTERLL-LSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLP 95
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT--FRDLSALERLDFSNN 151
+R L+L ++ + L DAF G +S+ ++ FR+L AL RLD S N
Sbjct: 96 NLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKN 155
Query: 152 RLVT-FEPETFEPLSSLKILSLRNNSI 177
++ + + +F L+SLK + +N I
Sbjct: 156 QIRSLYLHPSFGKLNSLKSIDFSSNQI 182
Score = 43.6 bits (98), Expect = 0.002
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE-SVDQLGFHSLPSLRHLDLSDNNMT 250
E L LS N I+ V+ PFL++L+ L+L + ++D+ F +LP+LR LDL + +
Sbjct: 49 ERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIY 108
Query: 251 LIPTSALSKLSNLSHLYL 268
+ A L +L L L
Sbjct: 109 FLHPDAFQGLFHLFELRL 126
Score = 42.7 bits (96), Expect = 0.003
Identities = 26/104 (25%), Positives = 51/104 (49%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SS++ L L + + + S + L+ L+L+ N I +++ L L+ L+L+ N+
Sbjct: 288 SSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNL 347
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ + F+ LP + ++DL N++ +I L L L L
Sbjct: 348 LGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDL 391
Score = 40.3 bits (90), Expect = 0.018
Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRL-VTFEPETFEPLSSLKILSLRNNSILDI-PSANLG 186
I + +F L L+ L+ + +T + E F L +L+IL L ++ I + P A G
Sbjct: 58 IRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQG 117
Query: 187 FVIHLEYLDLSE-NLIQQVSRHG-LPFLKELKHLDLNNNIIESVD-QLGFHSLPSLRHLD 243
+ HL L L L V + G LK L LDL+ N I S+ F L SL+ +D
Sbjct: 118 -LFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSID 176
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLS 269
S N + L+ L L + + S
Sbjct: 177 FSSNQIFLVCEHELEPLQGKTLSFFS 202
Score = 35.9 bits (79), Expect = 0.38
Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 25/231 (10%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK-RLDKDA-FVGXXXXXX 121
AF L +LD+ +KI L + F+ + L L L + KD F
Sbjct: 90 AFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTR 149
Query: 122 XXXXXXEISNIHVQ-TFRDLSALERLDFSNNRLVTFEPETFEPLS--SLKILSLRNNSIL 178
+I ++++ +F L++L+ +DFS+N++ EPL +L SL NS+
Sbjct: 150 LDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLY 209
Query: 179 DIPSANLGFVIH------LEYLDLS------------ENLIQQVSRHGLPFLKELKHLDL 220
S + G ++ LE LD+S N I + L +
Sbjct: 210 SRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGF 269
Query: 221 NNNIIESVDQLGFHSLP--SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ I+ DQ F L S+RHLDLS + + + L +L L L+
Sbjct: 270 GFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLA 320
Score = 34.7 bits (76), Expect = 0.88
Identities = 19/55 (34%), Positives = 31/55 (56%)
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++HLDL++ + S++ F +L L+ L+L+ N + I A L NL L LS
Sbjct: 290 VRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLS 344
>BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
>AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein.
Length = 649
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
>AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5
protein.
Length = 858
Score = 66.9 bits (156), Expect = 2e-10
Identities = 69/224 (30%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 51 MNLTHNAIDNL-LYAFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLKRLD 109
++L+H + +L F L VL+++YNKI + E F ++ LNLS N L L
Sbjct: 293 LDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNLLGELY 352
Query: 110 KDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNRLVTFEPETFEPLSSLKI 169
F G I+ I QTF+ L L+ LD +N L T F P S+
Sbjct: 353 SSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIH---FIP--SIPD 407
Query: 170 LSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLD---LNNNIIE 226
+ L N ++ +P NL + LSEN ++ + L FL + HL LN N
Sbjct: 408 IFLSGNKLVTLPKINL----TANLIHLSENRLENLDI--LYFLLRVPHLQILILNQNRFS 461
Query: 227 SV--DQLGFHSLPSLRHLDLSDNNMTLIPTSAL--SKLSNLSHL 266
S DQ + PSL L L +N + L + L LSHL
Sbjct: 462 SCSGDQTPSEN-PSLEQLFLGENMLQLAWETELCWDVFEGLSHL 504
Score = 56.8 bits (131), Expect = 2e-07
Identities = 35/112 (31%), Positives = 56/112 (50%)
Query: 141 SALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENL 200
S++ LD S+ + + FE L LK+L+L N I I + +L+ L+LS NL
Sbjct: 288 SSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNL 347
Query: 201 IQQVSRHGLPFLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLI 252
+ ++ L ++ ++DL N I + F L L+ LDL DN +T I
Sbjct: 348 LGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTI 399
Score = 44.4 bits (100), Expect = 0.001
Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 6/147 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLYA-FNLYTQLTVLDI-SYNKILDLGSENFESNS 93
NL VP LN L+ L+ N I + + F QL +L++ S L + E F +
Sbjct: 37 NLTQVPQVLNTTERLL-LSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLP 95
Query: 94 EMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQT--FRDLSALERLDFSNN 151
+R L+L ++ + L DAF G +S+ ++ FR+L AL RLD S N
Sbjct: 96 NLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKN 155
Query: 152 RLVT-FEPETFEPLSSLKILSLRNNSI 177
++ + + +F L+SLK + +N I
Sbjct: 156 QIRSLYLHPSFGKLNSLKSIDFSSNQI 182
Score = 43.6 bits (98), Expect = 0.002
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
Query: 192 EYLDLSENLIQQVSRHGLPFLKELKHLDLNNNIIE-SVDQLGFHSLPSLRHLDLSDNNMT 250
E L LS N I+ V+ PFL++L+ L+L + ++D+ F +LP+LR LDL + +
Sbjct: 49 ERLLLSFNYIRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIY 108
Query: 251 LIPTSALSKLSNLSHLYL 268
+ A L +L L L
Sbjct: 109 FLHPDAFQGLFHLFELRL 126
Score = 42.7 bits (96), Expect = 0.003
Identities = 26/104 (25%), Positives = 51/104 (49%)
Query: 165 SSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLPFLKELKHLDLNNNI 224
SS++ L L + + + S + L+ L+L+ N I +++ L L+ L+L+ N+
Sbjct: 288 SSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLSYNL 347
Query: 225 IESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
+ + F+ LP + ++DL N++ +I L L L L
Sbjct: 348 LGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDL 391
Score = 40.3 bits (90), Expect = 0.018
Identities = 44/146 (30%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
Query: 129 ISNIHVQTFRDLSALERLDFSNNRL-VTFEPETFEPLSSLKILSLRNNSILDI-PSANLG 186
I + +F L L+ L+ + +T + E F L +L+IL L ++ I + P A G
Sbjct: 58 IRTVTASSFPFLEQLQLLELGSQYTPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQG 117
Query: 187 FVIHLEYLDLSE-NLIQQVSRHG-LPFLKELKHLDLNNNIIESVD-QLGFHSLPSLRHLD 243
+ HL L L L V + G LK L LDL+ N I S+ F L SL+ +D
Sbjct: 118 -LFHLFELRLYFCGLSDAVLKDGYFRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSID 176
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLS 269
S N + L+ L L + + S
Sbjct: 177 FSSNQIFLVCEHELEPLQGKTLSFFS 202
Score = 35.9 bits (79), Expect = 0.38
Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 25/231 (10%)
Query: 64 AFNLYTQLTVLDISYNKILDLGSENFESNSEMRHLNLSNNFLK-RLDKDA-FVGXXXXXX 121
AF L +LD+ +KI L + F+ + L L L + KD F
Sbjct: 90 AFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAVLKDGYFRNLKALTR 149
Query: 122 XXXXXXEISNIHVQ-TFRDLSALERLDFSNNRLVTFEPETFEPLS--SLKILSLRNNSIL 178
+I ++++ +F L++L+ +DFS+N++ EPL +L SL NS+
Sbjct: 150 LDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSFFSLAANSLY 209
Query: 179 DIPSANLGFVIH------LEYLDLS------------ENLIQQVSRHGLPFLKELKHLDL 220
S + G ++ LE LD+S N I + L +
Sbjct: 210 SRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLILAHHIMGAGF 269
Query: 221 NNNIIESVDQLGFHSLP--SLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
+ I+ DQ F L S+RHLDLS + + + L +L L L+
Sbjct: 270 GFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNLA 320
Score = 34.7 bits (76), Expect = 0.88
Identities = 19/55 (34%), Positives = 31/55 (56%)
Query: 215 LKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYLS 269
++HLDL++ + S++ F +L L+ L+L+ N + I A L NL L LS
Sbjct: 290 VRHLDLSHGFVFSLNSRVFETLKDLKVLNLAYNKINKIADEAFYGLDNLQVLNLS 344
>AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine rich
transmembrane protein 3 protein.
Length = 649
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
>AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ90428 fis, clone NT2RP3000616, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 649
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
>AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens
cDNA FLJ90402 fis, clone NT2RP2006004, highly similar to
Leucine-rich repeat transmembrane protein FLRT3
precursor. ).
Length = 627
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
>AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ14788 fis, clone NT2RP4000925, weakly similar to
FIBROMODULIN PRECURSOR. ).
Length = 623
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 43 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 99
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 100 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 155
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 156 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 214
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 215 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 273
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 274 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 321
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 322 LNAELFDCKDSGIV 335
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 5 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 62
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 63 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 120
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 121 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 180
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 181 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 240
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 241 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 276
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 68 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 127
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 128 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 184
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 185 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 242
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 243 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 279
>AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens
cDNA FLJ14391 fis, clone HEMBA1003077, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 649
Score = 66.9 bits (156), Expect = 2e-10
Identities = 73/314 (23%), Positives = 130/314 (41%), Gaps = 26/314 (8%)
Query: 128 EISNIHVQT-FRDLSALERLDFSNNRLVTFEPETFEPLSSLKILSLRNNSILDIPSANLG 186
+I+N + + ++L +ER+ +N L F T P +K L L+ N+I I +L
Sbjct: 69 QINNAGIPSDLKNLLKVERIYLYHNSLDEFP--TNLP-KYVKELHLQENNIRTITYDSLS 125
Query: 187 FVIHLEYLDLSENLIQQVSRHGLPFLKE--LKHLDLNNNIIESVDQLGFHSLP-SLRHLD 243
+ +LE L L +N + VS F L+ L L+ N + ++ LP ++ L
Sbjct: 126 KIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPW----GLPRTIEELR 181
Query: 244 LSDNNMTLIPTSALSKLSNLSHLYLSGXXXXXXXXXXXXXXXXXXXXXXXXXXXXERIDS 303
L DN ++ I + +L L++L L L G +
Sbjct: 182 LDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTA-A 240
Query: 304 RAFVDNINLQKIWMNDNVKVREVPPRLFHGNPKLTNIYMKNNALETLEASHFP-IDRLQE 362
+ NL+K+++ DN + VPP F +L + M NN L L F +D + +
Sbjct: 241 PVNLPGTNLRKLYLQDN-HINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQ 299
Query: 363 LEISGNPFACNCSLLWLWKLGKDSETTTKKSGNSSEFLKIDYEDVKCSGPLQLKGMLFVQ 422
L + NP+ C C + W+ + S +K++ + C P +++GM
Sbjct: 300 LILRNNPWYCGCKMKWV------------RDWLQSLPVKVNVRGLMCQAPEKVRGMAIKD 347
Query: 423 IPESEFGCSSGWVI 436
+ F C ++
Sbjct: 348 LNAELFDCKDSGIV 361
Score = 54.8 bits (126), Expect = 8e-07
Identities = 70/276 (25%), Positives = 111/276 (40%), Gaps = 28/276 (10%)
Query: 17 CPVRCMCDDALRAASCANANLEIVPIQLNPEATLMNLTHNAIDNLLYAFNLYTQLTVLDI 76
CP C CD C + L +P + +AT + L +N I+N +L L V I
Sbjct: 31 CPSVCRCDAGF--IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERI 88
Query: 77 -SYNKILDLGSENFESNSEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQ 135
Y+ LD N ++ L+L N ++ + D+ +S + ++
Sbjct: 89 YLYHNSLDEFPTNLP--KYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 146
Query: 136 --TFRDLSALERLDFSNNRLVTFE---PETFEPL------------SSLKILSLRNNSIL 178
FRD + L L S N L T P T E L SL+ L+ +L
Sbjct: 147 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVL 206
Query: 179 D---IPSANLGFVIHLEYLDLSENLIQQVSRHGLPFL---KELKHLDLNNNIIESVDQLG 232
D + + LG + ++L+E + + S P L+ L L +N I V
Sbjct: 207 DGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNA 266
Query: 233 FHSLPSLRHLDLSDNNMTLIPTSALSKLSNLSHLYL 268
F L L LD+S+NN++ +P L N++ L L
Sbjct: 267 FSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLIL 302
Score = 47.2 bits (107), Expect = 2e-04
Identities = 56/217 (25%), Positives = 93/217 (42%), Gaps = 10/217 (4%)
Query: 36 NLEIVPIQLNPEATLMNLTHNAIDNLLY-AFNLYTQLTVLDISYNKILDLGSEN--FESN 92
+L+ P L ++L N I + Y + + L L + N + + E F +
Sbjct: 94 SLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDS 153
Query: 93 SEMRHLNLSNNFLKRLDKDAFVGXXXXXXXXXXXXEISNIHVQTFRDLSALERLDFSNNR 152
+ +R L LS N L + IS I + + L++L+RL N
Sbjct: 154 NYLRLLFLSRNHLSTIPWGL---PRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNL 210
Query: 153 LVT--FEPETFEPLSSLKILSLRNNSILDIPSANLGFVIHLEYLDLSENLIQQVSRHGLP 210
L + F L +L LSL NS+ P NL +L L L +N I +V +
Sbjct: 211 LNNHGLGDKVFFNLVNLTELSLVRNSLTAAP-VNLPGT-NLRKLYLQDNHINRVPPNAFS 268
Query: 211 FLKELKHLDLNNNIIESVDQLGFHSLPSLRHLDLSDN 247
+L++L LD++NN + ++ Q F L ++ L L +N
Sbjct: 269 YLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 305
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,992,319
Number of Sequences: 224733
Number of extensions: 2995563
Number of successful extensions: 16958
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 575
Number of HSP's successfully gapped in prelim test: 239
Number of HSP's that attempted gapping in prelim test: 8873
Number of HSP's gapped (non-prelim): 4964
length of query: 565
length of database: 73,234,838
effective HSP length: 94
effective length of query: 471
effective length of database: 52,109,936
effective search space: 24543779856
effective search space used: 24543779856
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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