Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002623-TA|BGIBMGA002623-PA|IPR001547|Glycoside
hydrolase, family 5, IPR001734|Na+/solute symporter
(455 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC110492-1|AAI10493.1| 610|Homo sapiens solute carrier family 5... 177 5e-44
AY081220-1|AAL88746.1| 610|Homo sapiens putative apical iodide ... 177 5e-44
AF536217-1|AAP46194.1| 610|Homo sapiens sodium solute symporter... 177 7e-44
AF536216-1|AAP46193.1| 610|Homo sapiens sodium solute symporter... 177 7e-44
AY299482-1|AAQ73572.1| 618|Homo sapiens sodium-iodide related c... 171 6e-42
U66088-1|AAB17378.1| 643|Homo sapiens sodium iodide symporter p... 163 9e-40
D87920-1|BAA24835.1| 643|Homo sapiens sodium iodide symporter p... 163 9e-40
BC105049-1|AAI05050.1| 643|Homo sapiens solute carrier family 5... 163 9e-40
BC105047-1|AAI05048.1| 643|Homo sapiens solute carrier family 5... 163 9e-40
AC005796-2|AAC62827.1| 643|Homo sapiens sodium iodide symporter... 163 9e-40
BC015631-1|AAH15631.1| 635|Homo sapiens solute carrier family 5... 144 4e-34
BC012806-1|AAH12806.1| 635|Homo sapiens solute carrier family 5... 144 4e-34
AF116241-1|AAD37502.1| 635|Homo sapiens sodium-dependent multiv... 144 4e-34
AF081571-1|AAD37481.1| 635|Homo sapiens sodium-dependent multi-... 144 4e-34
AF069307-1|AAD31727.1| 635|Homo sapiens sodium-dependent multiv... 144 4e-34
AC013403-8|AAX93172.1| 635|Homo sapiens unknown protein. 144 4e-34
BC049207-1|AAH49207.1| 396|Homo sapiens solute carrier family 5... 138 5e-32
BC041454-1|AAH41454.1| 392|Homo sapiens SLC5A12 protein protein. 138 5e-32
AY044906-1|AAK97784.1| 675|Homo sapiens sodium/glucose cotransp... 70 1e-11
AJ305237-1|CAC83728.1| 675|Homo sapiens sodium-dependent glucos... 70 1e-11
BC057780-1|AAH57780.1| 611|Homo sapiens SLC5A11 protein protein. 70 2e-11
AK125267-1|BAC86105.1| 742|Homo sapiens protein ( Homo sapiens ... 70 2e-11
AF292385-1|AAK97053.1| 675|Homo sapiens putative sodium-coupled... 70 2e-11
BC034380-1|AAH34380.1| 591|Homo sapiens SLC5A10 protein protein. 65 6e-10
AL109659-1|CAI18915.1| 699|Homo sapiens solute carrier family 5... 63 2e-09
Z83849-1|CAI23589.1| 664|Homo sapiens solute carrier family 5 (... 63 2e-09
Z83839-4|CAB06087.1| 664|Homo sapiens solute carrier family 5 (... 63 2e-09
Z80998-1|CAI18759.1| 664|Homo sapiens solute carrier family 5 (... 63 2e-09
Z74021-2|CAI18756.1| 664|Homo sapiens solute carrier family 5 (... 63 2e-09
M24847-1|AAA60320.1| 664|Homo sapiens SGLT1 protein. 63 2e-09
L29339-1|AAB59448.1| 664|Homo sapiens Na+/glucose cotransporter... 63 2e-09
CR456579-1|CAG30465.1| 664|Homo sapiens SLC5A1 protein. 63 2e-09
BC139839-1|AAI39840.2| 669|Homo sapiens SLC5A1 protein protein. 63 2e-09
BC104863-1|AAI04864.1| 681|Homo sapiens SLC5A9 protein protein. 63 2e-09
BC104857-1|AAI04858.1| 681|Homo sapiens SLC5A9 protein protein. 63 2e-09
AL022321-1|CAI19810.1| 664|Homo sapiens solute carrier family 5... 63 2e-09
AL008723-4|CAB51758.1| 659|Homo sapiens solute carrier family 5... 60 2e-08
AJ133127-1|CAB81772.1| 659|Homo sapiens sodium-glucose cotransp... 60 2e-08
AK075078-1|BAC11387.1| 257|Homo sapiens protein ( Homo sapiens ... 49 4e-05
BC062617-1|AAH62617.1| 567|Homo sapiens SLC5A10 protein protein. 46 4e-04
AK057946-1|BAB71619.1| 517|Homo sapiens protein ( Homo sapiens ... 45 6e-04
U41897-1|AAB61732.1| 175|Homo sapiens low affinity sodium gluco... 43 0.002
U41898-1|AAB61733.1| 178|Homo sapiens RKST1 protein. 43 0.003
L38500-1|AAC41747.2| 718|Homo sapiens Na+/myo-inositol cotransp... 43 0.003
AF027153-1|AAC39548.1| 718|Homo sapiens sodium/myo-inositol cot... 43 0.003
M95549-1|AAA36608.1| 672|Homo sapiens sodium/glucose cotranspor... 39 0.032
AF307340-1|AAL66409.1| 698|Homo sapiens sodium/glucose cotransp... 39 0.032
BC049385-1|AAH49385.1| 519|Homo sapiens SLC5A11 protein protein. 38 0.056
BC131542-1|AAI31543.1| 458|Homo sapiens SLC5A2 protein protein. 38 0.097
AB045125-1|BAD83600.1| 361|Homo sapiens KPG_013 protein protein. 31 6.4
>BC110492-1|AAI10493.1| 610|Homo sapiens solute carrier family 5
(iodide transporter), member 8 protein.
Length = 610
Score = 177 bits (432), Expect = 5e-44
Identities = 85/269 (31%), Positives = 148/269 (55%), Gaps = 1/269 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV Q +MV+ VI ++ ++ GGI+ +L + RL F + + +R
Sbjct: 180 GGLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQR 239
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++ IG TF W VNQS +QR+++ AK + + GL
Sbjct: 240 HTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGL 299
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
Y++Y++CDP + V+D+ D+ G+PG+F+A +S LS++S+ +N+
Sbjct: 300 ALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINA 359
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+AAV +ED KP+ + + + I + + ++ G +C G+ + +G++LQ +S+
Sbjct: 360 LAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGM 419
Query: 367 SMGPLAGVFLMGLFFPFIDSTVRWYVGLL 395
GPL G+F +G+ PF +S + VGL+
Sbjct: 420 VGGPLMGLFALGILVPFANS-IGALVGLM 447
Score = 102 bits (244), Expect = 3e-21
Identities = 51/108 (47%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Query: 20 FTYVDYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGI 78
F DY VF ML I IGIY+ F Q++++D+LMGGR M VPV SL ASF+S +
Sbjct: 10 FVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAV 69
Query: 79 SLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
++LGTP+E+Y FG + F + +I FLPVF++L ITS YE
Sbjct: 70 TVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYE 117
>AY081220-1|AAL88746.1| 610|Homo sapiens putative apical iodide
transporter protein.
Length = 610
Score = 177 bits (432), Expect = 5e-44
Identities = 85/269 (31%), Positives = 148/269 (55%), Gaps = 1/269 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV Q +MV+ VI ++ ++ GGI+ +L + RL F + + +R
Sbjct: 180 GGLKAVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQR 239
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++ IG TF W VNQS +QR+++ AK + + GL
Sbjct: 240 HTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGL 299
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
Y++Y++CDP + V+D+ D+ G+PG+F+A +S LS++S+ +N+
Sbjct: 300 ALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINA 359
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+AAV +ED KP+ + + + I + + ++ G +C G+ + +G++LQ +S+
Sbjct: 360 LAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGM 419
Query: 367 SMGPLAGVFLMGLFFPFIDSTVRWYVGLL 395
GPL G+F +G+ PF +S + VGL+
Sbjct: 420 VGGPLMGLFALGILVPFANS-IGALVGLM 447
Score = 102 bits (244), Expect = 3e-21
Identities = 51/108 (47%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Query: 20 FTYVDYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGI 78
F DY VF ML I IGIY+ F Q++++D+LMGGR M VPV SL ASF+S +
Sbjct: 10 FVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAV 69
Query: 79 SLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
++LGTP+E+Y FG + F + +I FLPVF++L ITS YE
Sbjct: 70 TVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYE 117
>AF536217-1|AAP46194.1| 610|Homo sapiens sodium solute symporter
family 5 member 8 protein protein.
Length = 610
Score = 177 bits (431), Expect = 7e-44
Identities = 85/269 (31%), Positives = 148/269 (55%), Gaps = 1/269 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV Q +MV+ VI ++ ++ GGI+ +L + RL F + + +R
Sbjct: 180 GGLKAVIWTDVFQIGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQR 239
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++ IG TF W VNQS +QR+++ AK + + GL
Sbjct: 240 HTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGL 299
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
Y++Y++CDP + V+D+ D+ G+PG+F+A +S LS++S+ +N+
Sbjct: 300 ALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINA 359
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+AAV +ED KP+ + + + I + + ++ G +C G+ + +G++LQ +S+
Sbjct: 360 LAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGM 419
Query: 367 SMGPLAGVFLMGLFFPFIDSTVRWYVGLL 395
GPL G+F +G+ PF +S + VGL+
Sbjct: 420 VGGPLMGLFALGILVPFANS-IGALVGLM 447
Score = 102 bits (244), Expect = 3e-21
Identities = 51/108 (47%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Query: 20 FTYVDYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGI 78
F DY VF ML I IGIY+ F Q++++D+LMGGR M VPV SL ASF+S +
Sbjct: 10 FVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAV 69
Query: 79 SLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
++LGTP+E+Y FG + F + +I FLPVF++L ITS YE
Sbjct: 70 TVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYE 117
>AF536216-1|AAP46193.1| 610|Homo sapiens sodium solute symporter
family 5 member 8 protein protein.
Length = 610
Score = 177 bits (431), Expect = 7e-44
Identities = 85/269 (31%), Positives = 148/269 (55%), Gaps = 1/269 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV Q +MV+ VI ++ ++ GGI+ +L + RL F + + +R
Sbjct: 180 GGLKAVIWTDVFQIGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQR 239
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++ IG TF W VNQS +QR+++ AK + + GL
Sbjct: 240 HTFWTIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGL 299
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
Y++Y++CDP + V+D+ D+ G+PG+F+A +S LS++S+ +N+
Sbjct: 300 ALYSRYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINA 359
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+AAV +ED KP+ + + + I + + ++ G +C G+ + +G++LQ +S+
Sbjct: 360 LAAVTVEDLIKPYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGM 419
Query: 367 SMGPLAGVFLMGLFFPFIDSTVRWYVGLL 395
GPL G+F +G+ PF +S + VGL+
Sbjct: 420 VGGPLMGLFALGILVPFANS-IGALVGLM 447
Score = 102 bits (244), Expect = 3e-21
Identities = 51/108 (47%), Positives = 68/108 (62%), Gaps = 1/108 (0%)
Query: 20 FTYVDYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGI 78
F DY VF ML I IGIY+ F Q++++D+LMGGR M VPV SL ASF+S +
Sbjct: 10 FVVWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAV 69
Query: 79 SLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
++LGTP+E+Y FG + F + +I FLPVF++L ITS YE
Sbjct: 70 TVLGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYE 117
>AY299482-1|AAQ73572.1| 618|Homo sapiens sodium-iodide related
cotransporter protein.
Length = 618
Score = 171 bits (415), Expect = 6e-42
Identities = 83/259 (32%), Positives = 137/259 (52%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAVVWTD Q +VM+ + V+ + + GG + VL ++ + RL D R
Sbjct: 176 GGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRR 235
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++++G TF W+G VNQS +QR ++ K AK A +SGL
Sbjct: 236 HTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWVILVCAVFSGL 295
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
+ Y+ + +CDP S VM++F G+PG+F+A FS LS++++ +N+
Sbjct: 296 IMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINA 355
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V EDF K + K S I + + ++ G +C + +G V+Q ++S+
Sbjct: 356 LATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMSVAASVMGGVVQASLSIHGM 415
Query: 367 SMGPLAGVFLMGLFFPFID 385
GP+ G+F +G+ FPF++
Sbjct: 416 CGGPMLGLFSLGIVFPFVN 434
Score = 90.6 bits (215), Expect = 1e-17
Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 1/111 (0%)
Query: 17 LQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKST-QDYLMGGRNMKLVPVCFSLVASFI 75
++ F DY VF + I IG++F ++K+T +++L+GGR M PV SL ASF+
Sbjct: 3 VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62
Query: 76 SGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
S +++LGTP+E+Y FG +++ + + L+ FLPVF+ ITS YE
Sbjct: 63 SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYE 113
>U66088-1|AAB17378.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 163 bits (397), Expect = 9e-40
Identities = 86/257 (33%), Positives = 133/257 (51%), Gaps = 1/257 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GG+KAVVWTDV Q +VM+S +V+ + ++VGG +VL + R+ D R
Sbjct: 182 GGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSR 241
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
++ W+ +G T W+ VNQ+ +QR++A K AK A G+
Sbjct: 242 YTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGI 301
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V + Y +CDPL V+D+F D G+PG+F+A +S LS+ ST +N+
Sbjct: 302 VMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINA 361
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL-GSVLQLTMSLSS 365
MAAV +ED KP + P++ II + + +I G C + + L G VLQ + ++
Sbjct: 362 MAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMG 421
Query: 366 ASMGPLAGVFLMGLFFP 382
GPL G F++G+F P
Sbjct: 422 VISGPLLGAFILGMFLP 438
Score = 86.6 bits (205), Expect = 2e-16
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLG 82
DY VF +ML + IG++ G Q+S +D+ GGR + +PV SL ASF+S + +LG
Sbjct: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
Query: 83 TPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
P+E Y +G +++ G + S++ F+PVF+ L +TS YE
Sbjct: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYE 119
>D87920-1|BAA24835.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 163 bits (397), Expect = 9e-40
Identities = 86/257 (33%), Positives = 133/257 (51%), Gaps = 1/257 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GG+KAVVWTDV Q +VM+S +V+ + ++VGG +VL + R+ D R
Sbjct: 182 GGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSR 241
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
++ W+ +G T W+ VNQ+ +QR++A K AK A G+
Sbjct: 242 YTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGI 301
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V + Y +CDPL V+D+F D G+PG+F+A +S LS+ ST +N+
Sbjct: 302 VMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINA 361
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL-GSVLQLTMSLSS 365
MAAV +ED KP + P++ II + + +I G C + + L G VLQ + ++
Sbjct: 362 MAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMG 421
Query: 366 ASMGPLAGVFLMGLFFP 382
GPL G F++G+F P
Sbjct: 422 VISGPLLGAFILGMFLP 438
Score = 85.8 bits (203), Expect = 3e-16
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLG 82
DY VF +ML + IG++ G Q+S +D+ GGR + +PV SL ASF+S + +LG
Sbjct: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
Query: 83 TPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
P+E Y +G +++ G + S++ F+PVF+ L +TS YE
Sbjct: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTPLLFMPVFYRLGLTSTYE 119
>BC105049-1|AAI05050.1| 643|Homo sapiens solute carrier family 5
(sodium iodide symporter), member 5 protein.
Length = 643
Score = 163 bits (397), Expect = 9e-40
Identities = 86/257 (33%), Positives = 133/257 (51%), Gaps = 1/257 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GG+KAVVWTDV Q +VM+S +V+ + ++VGG +VL + R+ D R
Sbjct: 182 GGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSR 241
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
++ W+ +G T W+ VNQ+ +QR++A K AK A G+
Sbjct: 242 YTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGI 301
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V + Y +CDPL V+D+F D G+PG+F+A +S LS+ ST +N+
Sbjct: 302 VMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINA 361
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL-GSVLQLTMSLSS 365
MAAV +ED KP + P++ II + + +I G C + + L G VLQ + ++
Sbjct: 362 MAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMG 421
Query: 366 ASMGPLAGVFLMGLFFP 382
GPL G F++G+F P
Sbjct: 422 VISGPLLGAFILGMFLP 438
Score = 86.6 bits (205), Expect = 2e-16
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLG 82
DY VF +ML + IG++ G Q+S +D+ GGR + +PV SL ASF+S + +LG
Sbjct: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
Query: 83 TPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
P+E Y +G +++ G + S++ F+PVF+ L +TS YE
Sbjct: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYE 119
>BC105047-1|AAI05048.1| 643|Homo sapiens solute carrier family 5
(sodium iodide symporter), member 5 protein.
Length = 643
Score = 163 bits (397), Expect = 9e-40
Identities = 86/257 (33%), Positives = 133/257 (51%), Gaps = 1/257 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GG+KAVVWTDV Q +VM+S +V+ + ++VGG +VL + R+ D R
Sbjct: 182 GGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSR 241
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
++ W+ +G T W+ VNQ+ +QR++A K AK A G+
Sbjct: 242 YTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGI 301
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V + Y +CDPL V+D+F D G+PG+F+A +S LS+ ST +N+
Sbjct: 302 VMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINA 361
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL-GSVLQLTMSLSS 365
MAAV +ED KP + P++ II + + +I G C + + L G VLQ + ++
Sbjct: 362 MAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMG 421
Query: 366 ASMGPLAGVFLMGLFFP 382
GPL G F++G+F P
Sbjct: 422 VISGPLLGAFILGMFLP 438
Score = 86.6 bits (205), Expect = 2e-16
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLG 82
DY VF +ML + IG++ G Q+S +D+ GGR + +PV SL ASF+S + +LG
Sbjct: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
Query: 83 TPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
P+E Y +G +++ G + S++ F+PVF+ L +TS YE
Sbjct: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYE 119
>AC005796-2|AAC62827.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 163 bits (397), Expect = 9e-40
Identities = 86/257 (33%), Positives = 133/257 (51%), Gaps = 1/257 (0%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GG+KAVVWTDV Q +VM+S +V+ + ++VGG +VL + R+ D R
Sbjct: 182 GGMKAVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSR 241
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
++ W+ +G T W+ VNQ+ +QR++A K AK A G+
Sbjct: 242 YTFWTFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGI 301
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V + Y +CDPL V+D+F D G+PG+F+A +S LS+ ST +N+
Sbjct: 302 VMFVFYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINA 361
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL-GSVLQLTMSLSS 365
MAAV +ED KP + P++ II + + +I G C + + L G VLQ + ++
Sbjct: 362 MAAVTVEDLIKPRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMG 421
Query: 366 ASMGPLAGVFLMGLFFP 382
GPL G F++G+F P
Sbjct: 422 VISGPLLGAFILGMFLP 438
Score = 86.6 bits (205), Expect = 2e-16
Identities = 40/104 (38%), Positives = 63/104 (60%), Gaps = 1/104 (0%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNK-QKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLG 82
DY VF +ML + IG++ G Q+S +D+ GGR + +PV SL ASF+S + +LG
Sbjct: 16 DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
Query: 83 TPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
P+E Y +G +++ G + S++ F+PVF+ L +TS YE
Sbjct: 76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYE 119
>BC015631-1|AAH15631.1| 635|Homo sapiens solute carrier family 5
(sodium-dependent vitamin transporter), member 6
protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>BC012806-1|AAH12806.1| 635|Homo sapiens solute carrier family 5
(sodium-dependent vitamin transporter), member 6
protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>AF116241-1|AAD37502.1| 635|Homo sapiens sodium-dependent
multivitamin transporter protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>AF081571-1|AAD37481.1| 635|Homo sapiens sodium-dependent
multi-vitamin transporter protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>AF069307-1|AAD31727.1| 635|Homo sapiens sodium-dependent
multivitamin transporter protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>AC013403-8|AAX93172.1| 635|Homo sapiens unknown protein.
Length = 635
Score = 144 bits (350), Expect = 4e-34
Identities = 81/256 (31%), Positives = 129/256 (50%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAV+WTDV QT+VM + VI + VGG+ V R++ L D R
Sbjct: 194 GGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVR 253
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W+++ G F + VNQ+ +QR+L+ K+A + GL
Sbjct: 254 HTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGL 313
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
V +A Y E VMD+ G+PG+FIA +FS +LS++S+ NS
Sbjct: 314 VMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNS 373
Query: 307 MAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSA 366
+A V +ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+
Sbjct: 374 LATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGM 433
Query: 367 SMGPLAGVFLMGLFFP 382
GPL G+F +G+FFP
Sbjct: 434 VGGPLLGLFCLGMFFP 449
Score = 79.8 bits (188), Expect = 2e-14
Identities = 43/120 (35%), Positives = 65/120 (54%), Gaps = 1/120 (0%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQ-DYLMGGRNMKLVPV 66
S + + F+ +DY VF+++L + IG+Y + T + LM R M +PV
Sbjct: 12 SPTSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPV 71
Query: 67 CFSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
SL+A+F S +++LG P+E+Y FGT Y F LI F+PVF+ L +TS YE
Sbjct: 72 ALSLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYE 131
>BC049207-1|AAH49207.1| 396|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 12 protein.
Length = 396
Score = 138 bits (333), Expect = 5e-32
Identities = 66/191 (34%), Positives = 102/191 (53%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAVVWTD Q +VM+ + V+ + + GG + VL ++ + RL D R
Sbjct: 176 GGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRR 235
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++++G TF W+G VNQS +QR ++ K AK A +SGL
Sbjct: 236 HTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGL 295
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
+ Y+ + +CDP S VM++F G+PG+F+A FS LS++++ +N+
Sbjct: 296 IMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINA 355
Query: 307 MAAVVLEDFWK 317
+A V EDF K
Sbjct: 356 LATVTFEDFVK 366
Score = 90.6 bits (215), Expect = 1e-17
Identities = 43/111 (38%), Positives = 68/111 (61%), Gaps = 1/111 (0%)
Query: 17 LQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKST-QDYLMGGRNMKLVPVCFSLVASFI 75
++ F DY VF + I IG++F ++K+T +++L+GGR M PV SL ASF+
Sbjct: 3 VKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFM 62
Query: 76 SGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE 126
S +++LGTP+E+Y FG +++ + + L+ FLPVF+ ITS YE
Sbjct: 63 SAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYE 113
>BC041454-1|AAH41454.1| 392|Homo sapiens SLC5A12 protein protein.
Length = 392
Score = 138 bits (333), Expect = 5e-32
Identities = 66/191 (34%), Positives = 102/191 (53%)
Query: 127 GGLKAVVWTDVLQTIVMVSAMILVIFKSTIIVGGINEVLRRNWSTDRLAFPSLTFDLTER 186
GGLKAVVWTD Q +VM+ + V+ + + GG + VL ++ + RL D R
Sbjct: 103 GGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRR 162
Query: 187 HSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGL 246
H+ W++++G TF W+G VNQS +QR ++ K AK A +SGL
Sbjct: 163 HTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGL 222
Query: 247 VAYAKYYECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNS 306
+ Y+ + +CDP S VM++F G+PG+F+A FS LS++++ +N+
Sbjct: 223 IMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINA 282
Query: 307 MAAVVLEDFWK 317
+A V EDF K
Sbjct: 283 LATVTFEDFVK 293
>AY044906-1|AAK97784.1| 675|Homo sapiens sodium/glucose
cotransporter KST1 protein.
Length = 675
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 152 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIM 211
Query: 144 VSAMILVIFKSTIIVGGINEV-------LRRNWSTDRL-------AF----PSLTFDLTE 185
+ + ++ S VGG+ + L N S + AF LT DL
Sbjct: 212 LIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPW 271
Query: 186 RHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSG 245
++ +SI + +YW +Q ++QR LA L AK + G
Sbjct: 272 PGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPG 327
Query: 246 LVAYAKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAA 296
+V+ + + C + S V+++ G+ G+ +A + +A
Sbjct: 328 MVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPT--GLRGLMMAVMVAAL 385
Query: 297 LSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLG 354
+SSL++ NS + + D W + K+ I+ R+ V++L + + VV+ + G
Sbjct: 386 MSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGG 445
Query: 355 SVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ S+SS P+A VF+MG F+
Sbjct: 446 QLFIYIQSISSYLQPPVAVVFIMGCFW 472
>AJ305237-1|CAC83728.1| 675|Homo sapiens sodium-dependent glucose
transporter protein.
Length = 675
Score = 70.1 bits (164), Expect = 1e-11
Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 152 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIM 211
Query: 144 VSAMILVIFKSTIIVGGINEV-------LRRNWSTDRL-------AF----PSLTFDLTE 185
+ + ++ S VGG+ + L N S + AF LT DL
Sbjct: 212 LIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPW 271
Query: 186 RHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSG 245
++ +SI + +YW +Q ++QR LA L AK + G
Sbjct: 272 PGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPG 327
Query: 246 LVAYAKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAA 296
+V+ + + C + S V+++ G+ G+ +A + +A
Sbjct: 328 MVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPP--GLRGLMMAVMVAAL 385
Query: 297 LSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLG 354
+SSL++ NS + + D W + K+ I+ R+ V++L + + VV+ + G
Sbjct: 386 MSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGG 445
Query: 355 SVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ S+SS P+A VF+MG F+
Sbjct: 446 QLFIYIQSISSYLQPPVAVVFIMGCFW 472
>BC057780-1|AAH57780.1| 611|Homo sapiens SLC5A11 protein protein.
Length = 611
Score = 69.7 bits (163), Expect = 2e-11
Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 88 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIM 147
Query: 144 VSAMILVIFKSTIIVGGINEV-------LRRNWSTDRL-------AF----PSLTFDLTE 185
+ + ++ S VGG+ + L N S + AF LT DL
Sbjct: 148 LIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPW 207
Query: 186 RHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSG 245
++ +SI + +YW +Q ++QR LA L AK + G
Sbjct: 208 PGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPG 263
Query: 246 LVAYAKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAA 296
+V+ + + C + S V+++ G+ G+ +A + +A
Sbjct: 264 MVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPT--GLRGLMMAVMVAAL 321
Query: 297 LSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLG 354
+SSL++ NS + + D W + K+ I+ R+ V++L + + VV+ + G
Sbjct: 322 MSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGG 381
Query: 355 SVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ S+SS P+A VF+MG F+
Sbjct: 382 QLFIYIRSISSYLQPPVAVVFIMGCFW 408
>AK125267-1|BAC86105.1| 742|Homo sapiens protein ( Homo sapiens
cDNA FLJ43277 fis, clone KIDNE2011635, highly similar
to Rabbit mRNA for sodium-glucose cotransporter. ).
Length = 742
Score = 69.7 bits (163), Expect = 2e-11
Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 219 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIAGLLAITAVYTVAGGLAAVIYTDALQTLIM 278
Query: 144 VSAMILVIFKSTIIVGGINEV-------LRRNWSTDRL-------AF----PSLTFDLTE 185
+ + ++ S VGG+ + L N S + AF LT DL
Sbjct: 279 LIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPW 338
Query: 186 RHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSG 245
++ +SI + +YW +Q ++QR LA L AK + G
Sbjct: 339 PGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPG 394
Query: 246 LVAYAKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAA 296
+V+ + + C + S V+++ G+ G+ +A + +A
Sbjct: 395 MVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPT--GLRGLMMAVMVAAL 452
Query: 297 LSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLG 354
+SSL++ NS + + D W + K+ I+ R+ V++L + + VV+ + G
Sbjct: 453 MSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGG 512
Query: 355 SVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ S+SS P+A VF+MG F+
Sbjct: 513 QLFIYIQSISSYLQPPVAVVFIMGCFW 539
>AF292385-1|AAK97053.1| 675|Homo sapiens putative sodium-coupled
cotransporter RKST1 protein.
Length = 675
Score = 69.7 bits (163), Expect = 2e-11
Identities = 82/327 (25%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 152 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIAGLLAITAVYTVAGGLAAVIYTDALQTLIM 211
Query: 144 VSAMILVIFKSTIIVGGINEV-------LRRNWSTDRL-------AF----PSLTFDLTE 185
+ + ++ S VGG+ + L N S + AF LT DL
Sbjct: 212 LIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPW 271
Query: 186 RHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSG 245
++ +SI + +YW +Q ++QR LA L AK + G
Sbjct: 272 PGVLFGMSIPSLWYW----CTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPG 327
Query: 246 LVAYAKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAA 296
+V+ + + C + S V+++ G+ G+ +A + +A
Sbjct: 328 MVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPT--GLRGLMMAVMVAAL 385
Query: 297 LSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLG 354
+SSL++ NS + + D W + K+ I+ R+ V++L + + VV+ + G
Sbjct: 386 MSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGG 445
Query: 355 SVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ S+SS P+A VF+MG F+
Sbjct: 446 QLFIYIQSISSYLQPPVAVVFIMGCFW 472
>BC034380-1|AAH34380.1| 591|Homo sapiens SLC5A10 protein protein.
Length = 591
Score = 64.9 bits (151), Expect = 6e-10
Identities = 73/314 (23%), Positives = 134/314 (42%), Gaps = 38/314 (12%)
Query: 100 GAVAMSLILGSTF-LPVFHELQITSVYE--GGLKAVVWTDVLQTIVMVSAMILVIFKSTI 156
GA+ + + LG F L L IT++Y GGL AV++TD LQT++MV +++ K+
Sbjct: 152 GALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFD 211
Query: 157 IVGGINE--------VLRRNWSTDRLAFPSL----------TFDLTERHSIWSVSIGATF 198
+GG + + R + P T DL + ++I AT+
Sbjct: 212 QIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATW 271
Query: 199 YWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGLVAYAKY------ 252
YW +Q ++QR L+ +L AK G+++ A +
Sbjct: 272 YW----CTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPDDVGC 327
Query: 253 ---YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSLSTGLNSMAA 309
EC VM++ G+ G+ IA + +A +SSL++ NS +
Sbjct: 328 VVPSECLRACGAEVGCSNIAYPKLVMELMP--IGLRGLMIAVMLAALMSSLTSIFNSSST 385
Query: 310 VVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLGSVLQLTMSLSSAS 367
+ D W+ ++ ++ RLV++ L + + V++ G + S++S+
Sbjct: 386 LFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSL 445
Query: 368 MGPLAGVFLMGLFF 381
P+ VF++G+F+
Sbjct: 446 APPVTAVFVLGVFW 459
Score = 31.1 bits (67), Expect = 8.4
Identities = 29/136 (21%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 19 RFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGI 78
+ + D V + + +GI+ + + Y + GR+M P+ SL AS
Sbjct: 10 QLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSG 69
Query: 79 SLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAV 132
+G G A + A + L L F+P++ +I ++ E GG +
Sbjct: 70 LFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIR 129
Query: 133 VWTDVLQTIVMVSAMI 148
++ VL ++ V I
Sbjct: 130 MYLSVLSLLLSVFTKI 145
>AL109659-1|CAI18915.1| 699|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 9 protein.
Length = 699
Score = 63.3 bits (147), Expect = 2e-09
Identities = 71/322 (22%), Positives = 134/322 (41%), Gaps = 30/322 (9%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ + + LG + +L L +T+VY GGL AV++TD LQT++M
Sbjct: 179 LYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIM 238
Query: 144 VSAMILVIFKSTIIVGGINEVLRR-NWSTDRLAFPSLTFDLT--ERHSIWSVSIGATFYW 200
V ++++F VG + +R + + P+ T L + I + W
Sbjct: 239 VGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPW 298
Query: 201 IGNI-----------AVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGLVAY 249
G I +Q ++QR L+ L AK G+++
Sbjct: 299 PGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISR 358
Query: 250 AKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSL 300
A + + C + VM + G+ G+ IA + +A +SSL
Sbjct: 359 ALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSL 416
Query: 301 STGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLGSVLQ 358
++ NS + + D W+ F + T ++ ++ R+ V+ L I + +++ G +
Sbjct: 417 TSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFD 476
Query: 359 LTMSLSSASMGPLAGVFLMGLF 380
+++S P+ +FL+ +F
Sbjct: 477 YIQAVTSYLAPPITALFLLAIF 498
>Z83849-1|CAI23589.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>Z83839-4|CAB06087.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>Z80998-1|CAI18759.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>Z74021-2|CAI18756.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>M24847-1|AAA60320.1| 664|Homo sapiens SGLT1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>L29339-1|AAB59448.1| 664|Homo sapiens Na+/glucose cotransporter
protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>CR456579-1|CAG30465.1| 664|Homo sapiens SLC5A1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>BC139839-1|AAI39840.2| 669|Homo sapiens SLC5A1 protein protein.
Length = 669
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>BC104863-1|AAI04864.1| 681|Homo sapiens SLC5A9 protein protein.
Length = 681
Score = 62.9 bits (146), Expect = 2e-09
Identities = 70/322 (21%), Positives = 134/322 (41%), Gaps = 30/322 (9%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ + + LG + +L L +T+VY GGL AV++TD LQT++M
Sbjct: 161 LYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIM 220
Query: 144 VSAMILVIFKSTIIVGGINEVLRR-NWSTDRLAFPSLTFDLTERHSIWSVS--IGATFYW 200
V ++++F VG + +R + + P+ T L + + + W
Sbjct: 221 VGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHMLRDPVSGDIPW 280
Query: 201 IGNI-----------AVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGLVAY 249
G I +Q ++QR L+ L AK G+++
Sbjct: 281 PGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISR 340
Query: 250 AKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSL 300
A + + C + VM + G+ G+ IA + +A +SSL
Sbjct: 341 ALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSL 398
Query: 301 STGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLGSVLQ 358
++ NS + + D W+ F + T ++ ++ R+ V+ L I + +++ G +
Sbjct: 399 TSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFD 458
Query: 359 LTMSLSSASMGPLAGVFLMGLF 380
+++S P+ +FL+ +F
Sbjct: 459 YIQAVTSYLAPPITALFLLAIF 480
Score = 34.7 bits (76), Expect = 0.68
Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D +V ++ +GI+ + + Y + GR+M P+ SL++S + +G
Sbjct: 37 DISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGL 96
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYEGGLKAVVWTDVLQTIVM 143
G A + A + L LG F+PV+ + ++ + LK +Q +
Sbjct: 97 AGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQ-YLKKRFGGQRIQVYMS 155
Query: 144 VSAMILVIFK--STIIVGG 160
V ++IL IF ST I G
Sbjct: 156 VLSLILYIFTKISTDIFSG 174
>BC104857-1|AAI04858.1| 681|Homo sapiens SLC5A9 protein protein.
Length = 681
Score = 62.9 bits (146), Expect = 2e-09
Identities = 70/322 (21%), Positives = 134/322 (41%), Gaps = 30/322 (9%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ + + LG + +L L +T+VY GGL AV++TD LQT++M
Sbjct: 161 LYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQTVIM 220
Query: 144 VSAMILVIFKSTIIVGGINEVLRR-NWSTDRLAFPSLTFDLTERHSIWSVS--IGATFYW 200
V ++++F VG + +R + + P+ T L + + + W
Sbjct: 221 VGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHMLRDPVSGDIPW 280
Query: 201 IGNI-----------AVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXXXXXYSGLVAY 249
G I +Q ++QR L+ L AK G+++
Sbjct: 281 PGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFIVMPGMISR 340
Query: 250 AKYYE---------CDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIAGVFSAALSSL 300
A + + C + VM + G+ G+ IA + +A +SSL
Sbjct: 341 ALFPDEVGCVDPDVCQRICGARVGCSNIAYPKLVMALMP--VGLRGLMIAVIMAALMSSL 398
Query: 301 STGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVE--KLGSVLQ 358
++ NS + + D W+ F + T ++ ++ R+ V+ L I + +++ G +
Sbjct: 399 TSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFD 458
Query: 359 LTMSLSSASMGPLAGVFLMGLF 380
+++S P+ +FL+ +F
Sbjct: 459 YIQAVTSYLAPPITALFLLAIF 480
Score = 34.7 bits (76), Expect = 0.68
Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D +V ++ +GI+ + + Y + GR+M P+ SL++S + +G
Sbjct: 37 DISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGLFIGL 96
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYEGGLKAVVWTDVLQTIVM 143
G A + A + L LG F+PV+ + ++ + LK +Q +
Sbjct: 97 AGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQ-YLKKRFGGQRIQVYMS 155
Query: 144 VSAMILVIFK--STIIVGG 160
V ++IL IF ST I G
Sbjct: 156 VLSLILYIFTKISTDIFSG 174
>AL022321-1|CAI19810.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 62.9 bits (146), Expect = 2e-09
Identities = 83/351 (23%), Positives = 151/351 (43%), Gaps = 48/351 (13%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F GA+ ++L LG + +L +F L IT++Y GGL AV++TD LQT++M
Sbjct: 152 LYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIM 211
Query: 144 -VSAMILVIFK------------------STIIVGGINEVLRRNWSTDR-----LAFPSL 179
V ++IL F TI+ G N + T R + L
Sbjct: 212 LVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDG-NTTFQEKCYTPRADSFHIFRDPL 270
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL I+ +SI +YW +Q ++QR L+ + K
Sbjct: 271 TGDLPWPGFIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMPMF 326
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ Y EC+ V+++ + G+ G+ ++
Sbjct: 327 IMVMPGMISRILYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLS 384
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ ++ +SSL++ NS + + D + K + K+ I RL +++L I V +V
Sbjct: 385 VMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIV 444
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWY---VGLLV 396
+ + G + S++S P+A VFL+ +F+ ++ ++ +GLL+
Sbjct: 445 QSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLILGLLI 495
Score = 38.3 bits (85), Expect = 0.056
Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D ++ ++ + +G++ F + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A + A+ + ++LG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSL 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L ++ + I IF I +
Sbjct: 148 LSLLLYIFTKISADIFSGAIFI 169
>AL008723-4|CAB51758.1| 659|Homo sapiens solute carrier family 5
(low affinity glucose cotransporter), member 4 protein.
Length = 659
Score = 59.7 bits (138), Expect = 2e-08
Identities = 84/356 (23%), Positives = 159/356 (44%), Gaps = 46/356 (12%)
Query: 78 ISLLGTPTELYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVW 134
+S+L + L +A +F+ GA+ + L LG +L +F L +T+VY GGL +V++
Sbjct: 145 LSILSLFICVVLLISADIFA--GAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202
Query: 135 TDVLQTIVM-VSAMILVIFK-----------------STIIVGGINEVLRRNWSTDRL-A 175
TD LQTI+M + + IL+ F + +V G N + + T R +
Sbjct: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADS 262
Query: 176 F----PSLTFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXX 231
F ++T D+ I+ + I A +YW NQ ++QR L ++ K A
Sbjct: 263 FHIFRDAVTGDIPWPGIIFGMPITALWYW----CTNQVIVQRCLCGKDMSHVKAACIMCA 318
Query: 232 XXXXXXXXXXXYSGLVAYAKYY---------ECDPLDSXXXXXXXXXXXXXVMDVFNDWE 282
G+++ Y EC V+++ +
Sbjct: 319 YLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMP--Q 376
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ ++ + ++ +SSL++ NS + + D + K + K+ I R+ V++L +
Sbjct: 377 GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVV 436
Query: 343 CFGLVFVVE--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLV 396
V +V+ + G ++ T S+SS P+A VF++ +F ++ ++ GL+V
Sbjct: 437 SIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFW-GLMV 491
Score = 38.3 bits (85), Expect = 0.056
Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D +V ++ + +G++ + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A V + + M LILG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSI 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L + V +I IF I +
Sbjct: 148 LSLFICVVLLISADIFAGAIFI 169
>AJ133127-1|CAB81772.1| 659|Homo sapiens sodium-glucose
cotransporter protein.
Length = 659
Score = 59.7 bits (138), Expect = 2e-08
Identities = 84/356 (23%), Positives = 159/356 (44%), Gaps = 46/356 (12%)
Query: 78 ISLLGTPTELYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVW 134
+S+L + L +A +F+ GA+ + L LG +L +F L +T+VY GGL +V++
Sbjct: 145 LSILSLFICVVLLISADIFA--GAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 202
Query: 135 TDVLQTIVM-VSAMILVIFK-----------------STIIVGGINEVLRRNWSTDRL-A 175
TD LQTI+M + + IL+ F + +V G N + + T R +
Sbjct: 203 TDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADS 262
Query: 176 F----PSLTFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXX 231
F ++T D+ I+ + I A +YW NQ ++QR L ++ K A
Sbjct: 263 FHIFRDAVTGDIPWPGIIFGMPITALWYW----CTNQVIVQRCLCGKDMSHVKAACIMCA 318
Query: 232 XXXXXXXXXXXYSGLVAYAKYY---------ECDPLDSXXXXXXXXXXXXXVMDVFNDWE 282
G+++ Y EC V+++ +
Sbjct: 319 YLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVGCTNYAYPTMVLELMP--Q 376
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ ++ + ++ +SSL++ NS + + D + K + K+ I R+ V++L +
Sbjct: 377 GLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRIFVLLLTVV 436
Query: 343 CFGLVFVVE--KLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLV 396
V +V+ + G ++ T S+SS P+A VF++ +F ++ ++ GL+V
Sbjct: 437 SIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFW-GLMV 491
Score = 38.3 bits (85), Expect = 0.056
Identities = 33/142 (23%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 24 DYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVCFSLVASFISGISLLGT 83
D +V ++ + +G++ + + + + GR+M P+ SL AS I +G
Sbjct: 28 DISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGL 87
Query: 84 PTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE------GGLKAVVWTDV 137
G A V + + M LILG F+P++ + + ++ E GG + V+ +
Sbjct: 88 AGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSI 147
Query: 138 LQTIVMVSAMILV-IFKSTIIV 158
L + V +I IF I +
Sbjct: 148 LSLFICVVLLISADIFAGAIFI 169
>AK075078-1|BAC11387.1| 257|Homo sapiens protein ( Homo sapiens
cDNA FLJ90597 fis, clone PLACE1001231, highly similar to
Sodium-dependent multivitamin transporter. ).
Length = 257
Score = 48.8 bits (111), Expect = 4e-05
Identities = 21/71 (29%), Positives = 41/71 (57%)
Query: 312 LEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSASMGPL 371
+ED +P+ + ++ ++ R + G +C G+ ++ ++G VLQ +S+ GPL
Sbjct: 1 MEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPL 60
Query: 372 AGVFLMGLFFP 382
G+F +G+FFP
Sbjct: 61 LGLFCLGMFFP 71
>BC062617-1|AAH62617.1| 567|Homo sapiens SLC5A10 protein protein.
Length = 567
Score = 45.6 bits (103), Expect = 4e-04
Identities = 46/213 (21%), Positives = 90/213 (42%), Gaps = 17/213 (7%)
Query: 180 TFDLTERHSIWSVSIGATFYWIGNIAVNQSMMQRFLALSELKSAKRAXXXXXXXXXXXXX 239
T DL + ++I AT+YW +Q ++QR L+ +L AK
Sbjct: 229 TGDLPWTGMTFGLTIMATWYW----CTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMG 284
Query: 240 XXXYSGLVAYAKY---------YECDPLDSXXXXXXXXXXXXXVMDVFNDWEGMPGIFIA 290
G+++ A + EC VM++ G+ G+ IA
Sbjct: 285 LIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPI--GLRGLMIA 342
Query: 291 GVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVV 350
+ +A +SSL++ NS + + D W+ ++ ++ RLV++ L + + V+
Sbjct: 343 VMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVL 402
Query: 351 E--KLGSVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ G + S++S+ P+ VF++G+F+
Sbjct: 403 QDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 435
Score = 31.5 bits (68), Expect = 6.4
Identities = 30/147 (20%), Positives = 58/147 (39%), Gaps = 6/147 (4%)
Query: 8 SDVADVRFSLQRFTYVDYAVFIMMLTICGLIGIYFGFVNKQKSTQDYLMGGRNMKLVPVC 67
+ +D+ + + D V + + +GI+ + + Y + GR+M P+
Sbjct: 2 NSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIG 61
Query: 68 FSLVASFISGISLLGTPTELYLFGTAYVFSLFGAVAMSLILGSTFLPVFHELQITSVYE- 126
SL AS +G G A + A + L L F+P++ +I ++ E
Sbjct: 62 ASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEY 121
Query: 127 -----GGLKAVVWTDVLQTIVMVSAMI 148
GG + ++ VL ++ V I
Sbjct: 122 IQKRYGGQRIRMYLSVLSLLLSVFTKI 148
>AK057946-1|BAB71619.1| 517|Homo sapiens protein ( Homo sapiens
cDNA FLJ25217 fis, clone REC08938, highly similar to
Oryctolagus cuniculus Na+/glucose cotransporter-related
protein ).
Length = 517
Score = 44.8 bits (101), Expect = 6e-04
Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 3/68 (4%)
Query: 100 GAVAMSLILGSTF-LPVFHELQITSVYE--GGLKAVVWTDVLQTIVMVSAMILVIFKSTI 156
GA+ + + LG F L L IT++Y GGL AV++TD LQT++MV +++ K+
Sbjct: 62 GALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFD 121
Query: 157 IVGGINEV 164
+GG ++
Sbjct: 122 QIGGYGQL 129
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/101 (24%), Positives = 54/101 (53%), Gaps = 2/101 (1%)
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ IA + +A +SSL++ NS + + D W+ ++ ++ RLV++ L +
Sbjct: 285 GLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGV 344
Query: 343 CFGLVFVVE--KLGSVLQLTMSLSSASMGPLAGVFLMGLFF 381
+ V++ G + S++S+ P+ VF++G+F+
Sbjct: 345 SVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 385
>U41897-1|AAB61732.1| 175|Homo sapiens low affinity sodium glucose
cotransporter SAAT1 protein.
Length = 175
Score = 43.2 bits (97), Expect = 0.002
Identities = 30/86 (34%), Positives = 51/86 (59%), Gaps = 5/86 (5%)
Query: 78 ISLLGTPTELYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVW 134
+S+L + L +A +F+ GA+ + L LG +L +F L +T+VY GGL +V++
Sbjct: 73 LSILSLFICVVLLISADIFA--GAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIY 130
Query: 135 TDVLQTIVMVSAMILVIFKSTIIVGG 160
TD LQTI+M+ +++ + VGG
Sbjct: 131 TDTLQTIIMLIGSFILMGFAFNEVGG 156
>U41898-1|AAB61733.1| 178|Homo sapiens RKST1 protein.
Length = 178
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 3/78 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 80 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIM 139
Query: 144 VSAMILVIFKSTIIVGGI 161
+ + ++ S VGG+
Sbjct: 140 LIGALTLMCYSFAAVGGM 157
>L38500-1|AAC41747.2| 718|Homo sapiens Na+/myo-inositol
cotransporter protein.
Length = 718
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F V GA+ + LG + ++ V + +T++ GGL AV++TD LQ ++M
Sbjct: 133 LYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLM 192
Query: 144 VSAMILVIFKSTIIVGGINEVLRRNW-STDRLAFPSLTFDLTERHS 188
+ + ++ S + +GG EV RR ++ + LT++L+ +S
Sbjct: 193 IIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNS 238
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ +A + +A +S L + NS + + D +K K + ++ I+ R+ V + I
Sbjct: 362 GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVI 421
Query: 343 CFGLV-FVVEKLGSVLQLTMS-LSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLVFRTT 400
V +VE G + L + ++ P+A +FL+ +F+ + +Y G+ F
Sbjct: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLG 481
Query: 401 EIALLKP---KLPDC 412
+ L+ + P+C
Sbjct: 482 AVRLILAFAYRAPEC 496
>AF027153-1|AAC39548.1| 718|Homo sapiens sodium/myo-inositol
cotransporter protein.
Length = 718
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/106 (29%), Positives = 58/106 (54%), Gaps = 4/106 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F V GA+ + LG + ++ V + +T++ GGL AV++TD LQ ++M
Sbjct: 133 LYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLM 192
Query: 144 VSAMILVIFKSTIIVGGINEVLRRNW-STDRLAFPSLTFDLTERHS 188
+ + ++ S + +GG EV RR ++ + LT++L+ +S
Sbjct: 193 IIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNS 238
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ +A + +A +S L + NS + + D +K K + ++ I+ R+ V + I
Sbjct: 362 GLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELMIVGRIFVAFMVVI 421
Query: 343 CFGLV-FVVEKLGSVLQLTMS-LSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLVFRTT 400
V +VE G + L + ++ P+A +FL+ +F+ + +Y G+ F
Sbjct: 422 SIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLG 481
Query: 401 EIALLKP---KLPDC 412
+ L+ + P+C
Sbjct: 482 AVRLILAFAYRAPEC 496
>M95549-1|AAA36608.1| 672|Homo sapiens sodium/glucose
cotransporter-like protein protein.
Length = 672
Score = 39.1 bits (87), Expect = 0.032
Identities = 34/146 (23%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ +A + +A +SSL++ NS + + D + ++ ++ RL V+ + +
Sbjct: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVV 436
Query: 343 CFGLVFVVEKL--GSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLVFRTT 400
+ VV+ G + ++SS P++ VF++ LF P ++ ++ GL+
Sbjct: 437 SVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFW-GLIGGLLM 495
Query: 401 EIALLKPKLPDCLFPRGEVQYLPSGC 426
+A L +P+ F G PS C
Sbjct: 496 GLARL---IPEFSFGSGSC-VQPSAC 517
Score = 37.5 bits (83), Expect = 0.097
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F V GAV + LG + + V L IT +Y GGL A+++TD +QT V+
Sbjct: 149 LYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVI 208
Query: 144 VSAMILVIFKSTIIVGG 160
+ +++ + VGG
Sbjct: 209 LGGACILMGYAFHEVGG 225
>AF307340-1|AAL66409.1| 698|Homo sapiens sodium/glucose
cotransporter protein.
Length = 698
Score = 39.1 bits (87), Expect = 0.032
Identities = 34/146 (23%), Positives = 69/146 (47%), Gaps = 7/146 (4%)
Query: 283 GMPGIFIAGVFSAALSSLSTGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCI 342
G+ G+ +A + +A +SSL++ NS + + D + ++ ++ RL V+ + +
Sbjct: 377 GLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVV 436
Query: 343 CFGLVFVVEKL--GSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWYVGLLVFRTT 400
+ VV+ G + ++SS P++ VF++ LF P ++ ++ GL+
Sbjct: 437 SVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFW-GLIGGLLM 495
Query: 401 EIALLKPKLPDCLFPRGEVQYLPSGC 426
+A L +P+ F G PS C
Sbjct: 496 GLARL---IPEFSFGSGSC-VQPSAC 517
Score = 37.5 bits (83), Expect = 0.097
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F V GAV + LG + + V L IT +Y GGL A+++TD +QT V+
Sbjct: 149 LYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVI 208
Query: 144 VSAMILVIFKSTIIVGG 160
+ +++ + VGG
Sbjct: 209 LGGACILMGYAFHEVGG 225
>BC049385-1|AAH49385.1| 519|Homo sapiens SLC5A11 protein protein.
Length = 519
Score = 38.3 bits (85), Expect = 0.056
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 4/81 (4%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
+Y+F V GA+ + L +L + L IT+VY GGL AV++TD LQT++M
Sbjct: 88 IYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIM 147
Query: 144 -VSAMILVIFKSTIIVGGINE 163
+ A+ L+ + G E
Sbjct: 148 LIGALTLMGYSDCPADSGCQE 168
Score = 33.1 bits (72), Expect = 2.1
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 302 TGLNSMAAVVLEDFWKPFCKVPTPKQSQIIVRLVVIILGCICFGLVFVVEKL--GSVLQL 359
T +S + + D W + K+ I+ R+ V++L + + VV+ G +
Sbjct: 235 TPAHSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGGQLFIY 294
Query: 360 TMSLSSASMGPLAGVFLMGLFF 381
S+SS P+A VF+MG F+
Sbjct: 295 IQSISSYLQPPVAVVFIMGCFW 316
>BC131542-1|AAI31543.1| 458|Homo sapiens SLC5A2 protein protein.
Length = 458
Score = 37.5 bits (83), Expect = 0.097
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 87 LYLFGTAYVFSLFGAVAMSLILG-STFLPVFHELQITSVYE--GGLKAVVWTDVLQTIVM 143
LY+F V GAV + LG + + V L IT +Y GGL A+++TD +QT V+
Sbjct: 149 LYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVI 208
Query: 144 VSAMILVIFKSTIIVGG 160
+ +++ + VGG
Sbjct: 209 LGGACILMGYAFHEVGG 225
>AB045125-1|BAD83600.1| 361|Homo sapiens KPG_013 protein protein.
Length = 361
Score = 31.5 bits (68), Expect = 6.4
Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 333 RLVVIILGCICFGLVFVVEKLGSVLQLTMSLSSASMGPLAGVFLMGLFFPFIDSTVRWYV 392
RLV+ ++ GL+FVV LG+V L + G A + ++ LF + T +
Sbjct: 36 RLVLSVVETTVLGLIFVVSLLGNVCALVLVARRRRRGATASL-VLNLFCADLLFTSAIPL 94
Query: 393 GLLVFRTTEIALLKPKLPDCLF 414
+LV R TE LL P + LF
Sbjct: 95 -VLVVRWTEAWLLGPVVCHLLF 115
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.327 0.140 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,339,360
Number of Sequences: 224733
Number of extensions: 2226856
Number of successful extensions: 10476
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 10298
Number of HSP's gapped (non-prelim): 117
length of query: 455
length of database: 73,234,838
effective HSP length: 92
effective length of query: 363
effective length of database: 52,559,402
effective search space: 19079062926
effective search space used: 19079062926
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 67 (31.1 bits)
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