Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002597-TA|BGIBMGA002597-PA|IPR003306|WIF,
IPR008266|Tyrosine protein kinase, active site, IPR000719|Protein
kinase, IPR001245|Tyrosine protein kinase, IPR002290|Serine/threonine
protein kinase, IPR011009|Protein kinase-like
(515 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 324 6e-88
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 322 2e-87
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 319 2e-86
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 312 2e-84
AB209405-1|BAD92642.1| 232|Homo sapiens RYK receptor-like tyros... 258 3e-68
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 188 5e-47
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 171 5e-42
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 171 5e-42
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 171 5e-42
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 171 5e-42
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 170 9e-42
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 170 9e-42
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 170 9e-42
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 170 9e-42
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 170 9e-42
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 170 9e-42
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 170 9e-42
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 169 2e-41
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 169 2e-41
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 169 3e-41
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 167 1e-40
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 163 1e-39
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 163 2e-39
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 163 2e-39
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 163 2e-39
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 163 2e-39
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 160 1e-38
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 160 1e-38
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 160 1e-38
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 160 1e-38
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 160 1e-38
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 160 1e-38
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 160 1e-38
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 157 7e-38
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 157 7e-38
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 157 7e-38
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 157 7e-38
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 157 7e-38
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 157 7e-38
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 157 7e-38
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 157 7e-38
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 155 4e-37
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 155 5e-37
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 155 5e-37
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 155 5e-37
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 155 5e-37
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 155 5e-37
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 155 5e-37
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 155 5e-37
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 153 1e-36
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 153 1e-36
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 153 1e-36
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 153 1e-36
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 153 1e-36
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 152 2e-36
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 152 2e-36
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 152 2e-36
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 152 2e-36
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 152 2e-36
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 152 2e-36
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 152 2e-36
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 152 2e-36
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 152 2e-36
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 152 2e-36
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 152 2e-36
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 152 2e-36
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 152 2e-36
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 152 2e-36
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 152 2e-36
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 152 2e-36
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 152 2e-36
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 152 2e-36
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 152 2e-36
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 152 2e-36
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 152 2e-36
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 152 2e-36
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 152 2e-36
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 152 2e-36
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 152 2e-36
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 152 2e-36
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 152 2e-36
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 152 2e-36
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 152 2e-36
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 152 2e-36
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 152 2e-36
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 152 2e-36
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 152 2e-36
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 151 4e-36
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 151 4e-36
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 151 4e-36
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 151 4e-36
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 151 4e-36
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 151 4e-36
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 151 4e-36
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 151 4e-36
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 151 4e-36
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 151 4e-36
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 151 4e-36
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 151 4e-36
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 151 4e-36
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 151 4e-36
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 151 4e-36
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 151 4e-36
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 151 4e-36
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 151 4e-36
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 148 4e-35
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 148 4e-35
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 148 4e-35
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 148 4e-35
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 148 4e-35
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 148 4e-35
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 148 4e-35
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 148 4e-35
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 147 9e-35
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 146 1e-34
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 146 2e-34
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 146 2e-34
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 146 2e-34
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 146 2e-34
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 146 2e-34
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 146 2e-34
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 146 2e-34
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 145 4e-34
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 142 4e-33
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 142 4e-33
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 142 4e-33
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 142 4e-33
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 142 4e-33
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 142 4e-33
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 142 4e-33
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 142 4e-33
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 142 4e-33
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 142 4e-33
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 142 4e-33
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 142 4e-33
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 140 8e-33
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 140 1e-32
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 140 1e-32
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 140 1e-32
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 140 1e-32
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 140 1e-32
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 140 1e-32
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 140 1e-32
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 140 1e-32
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 140 1e-32
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 140 1e-32
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 140 1e-32
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 140 1e-32
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 140 1e-32
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 140 1e-32
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 139 2e-32
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 139 2e-32
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 139 2e-32
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 139 2e-32
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 137 8e-32
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 136 1e-31
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 136 1e-31
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 136 1e-31
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 136 1e-31
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 136 1e-31
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 136 1e-31
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 136 1e-31
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 136 2e-31
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 136 2e-31
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 136 2e-31
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 136 2e-31
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 136 2e-31
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 134 5e-31
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 134 5e-31
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 134 5e-31
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 134 5e-31
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 134 5e-31
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 134 5e-31
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 134 5e-31
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 134 5e-31
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 134 5e-31
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 134 7e-31
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 134 7e-31
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 134 7e-31
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 134 7e-31
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 134 7e-31
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 134 9e-31
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 134 9e-31
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 134 9e-31
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 134 9e-31
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 134 9e-31
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 134 9e-31
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 132 2e-30
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 132 2e-30
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 131 5e-30
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 131 5e-30
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 131 5e-30
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 131 5e-30
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 130 2e-29
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 130 2e-29
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 130 2e-29
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 130 2e-29
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 130 2e-29
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 130 2e-29
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 128 5e-29
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 128 5e-29
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 128 5e-29
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 128 5e-29
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 128 5e-29
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 128 5e-29
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 128 5e-29
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 128 5e-29
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 127 8e-29
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 127 1e-28
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 127 1e-28
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 127 1e-28
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 126 1e-28
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 126 1e-28
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 126 1e-28
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 126 1e-28
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 126 1e-28
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 126 1e-28
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 126 1e-28
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 126 1e-28
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 126 1e-28
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 126 1e-28
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 126 1e-28
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 126 2e-28
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 126 2e-28
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 126 2e-28
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 126 2e-28
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 126 2e-28
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 124 8e-28
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 123 2e-27
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 123 2e-27
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 123 2e-27
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 123 2e-27
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 123 2e-27
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 122 2e-27
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 122 2e-27
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 122 3e-27
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 122 3e-27
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 122 3e-27
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 122 3e-27
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 122 3e-27
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 122 3e-27
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 122 4e-27
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 122 4e-27
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 122 4e-27
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 122 4e-27
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 122 4e-27
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 122 4e-27
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 122 4e-27
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 122 4e-27
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 122 4e-27
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 122 4e-27
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 122 4e-27
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 122 4e-27
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 122 4e-27
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 122 4e-27
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 122 4e-27
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 120 1e-26
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 120 1e-26
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 120 1e-26
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 120 1e-26
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 120 1e-26
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 120 1e-26
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 119 2e-26
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 119 2e-26
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 119 2e-26
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 119 3e-26
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 119 3e-26
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 119 3e-26
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 118 4e-26
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 118 4e-26
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 118 4e-26
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 118 4e-26
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 118 4e-26
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 118 4e-26
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 118 4e-26
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 118 4e-26
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 118 4e-26
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 118 4e-26
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 118 5e-26
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 118 5e-26
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 118 7e-26
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 117 9e-26
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 117 9e-26
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 117 9e-26
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 117 1e-25
U38894-1|AAC50714.1| 388|Homo sapiens tyrosine kinase t-Ror1 pr... 117 1e-25
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 117 1e-25
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 117 1e-25
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 117 1e-25
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 117 1e-25
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 117 1e-25
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 117 1e-25
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 117 1e-25
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 117 1e-25
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 117 1e-25
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 117 1e-25
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 117 1e-25
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 117 1e-25
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 116 2e-25
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 116 2e-25
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 116 2e-25
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 116 2e-25
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 116 2e-25
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 116 2e-25
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 116 2e-25
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 116 2e-25
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 116 2e-25
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 116 2e-25
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 116 2e-25
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 116 2e-25
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 116 2e-25
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 116 2e-25
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 116 2e-25
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 116 2e-25
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 116 3e-25
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 116 3e-25
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 116 3e-25
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 116 3e-25
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 115 3e-25
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 115 3e-25
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 115 3e-25
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 115 3e-25
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 115 3e-25
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 115 3e-25
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 115 3e-25
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 115 3e-25
AB209338-1|BAD92575.1| 400|Homo sapiens Hypothetical protein FL... 115 3e-25
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 115 3e-25
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 115 5e-25
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 115 5e-25
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 115 5e-25
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 115 5e-25
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 115 5e-25
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 115 5e-25
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 115 5e-25
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 115 5e-25
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 114 8e-25
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 114 8e-25
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 114 8e-25
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 114 8e-25
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 113 1e-24
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 113 1e-24
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 113 1e-24
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 113 1e-24
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 113 1e-24
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 113 1e-24
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 113 1e-24
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 113 1e-24
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 113 1e-24
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 113 2e-24
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 113 2e-24
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 113 2e-24
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 113 2e-24
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 113 2e-24
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 113 2e-24
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 113 2e-24
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 112 2e-24
AC012069-1|AAY15092.1| 479|Homo sapiens unknown protein. 112 2e-24
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 112 3e-24
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 112 3e-24
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 112 3e-24
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 112 3e-24
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 112 3e-24
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 112 3e-24
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 111 6e-24
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 111 6e-24
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 111 6e-24
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 111 6e-24
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 111 6e-24
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 111 8e-24
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 111 8e-24
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 110 1e-23
BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein. 110 1e-23
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 110 1e-23
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 110 1e-23
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 110 1e-23
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 110 1e-23
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 110 1e-23
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 110 1e-23
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 110 1e-23
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 110 1e-23
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 110 1e-23
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 110 1e-23
M21616-1|AAA36427.1| 1106|Homo sapiens platelet-derived growth f... 110 1e-23
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 110 1e-23
J03278-1|AAA60049.1| 1106|Homo sapiens platelet-derived growth f... 110 1e-23
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 110 1e-23
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 110 1e-23
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 110 1e-23
BC032224-1|AAH32224.1| 1106|Homo sapiens platelet-derived growth... 110 1e-23
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 110 1e-23
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 110 1e-23
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 110 1e-23
AB209657-1|BAD92894.1| 777|Homo sapiens platelet-derived growth... 110 1e-23
L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein. 109 2e-23
DQ836395-1|ABI53804.1| 556|Homo sapiens N2idVEGFR-1 protein. 109 2e-23
DQ836394-1|ABI53803.1| 556|Homo sapiens idVEGFR-1 protein. 109 2e-23
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 109 2e-23
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 109 2e-23
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 109 3e-23
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 109 3e-23
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 109 3e-23
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 109 3e-23
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 109 3e-23
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 109 3e-23
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 109 3e-23
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 108 4e-23
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 108 4e-23
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 108 4e-23
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 108 4e-23
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 108 4e-23
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 108 4e-23
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 108 4e-23
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 108 4e-23
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 108 5e-23
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 108 5e-23
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 108 5e-23
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 108 5e-23
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 108 5e-23
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 108 5e-23
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 108 5e-23
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 108 5e-23
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 108 5e-23
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 108 5e-23
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 108 5e-23
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 108 5e-23
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 108 5e-23
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 108 5e-23
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 108 5e-23
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 108 5e-23
AC073324-1|AAS07524.1| 387|Homo sapiens unknown protein. 108 5e-23
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 108 5e-23
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 108 5e-23
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 108 5e-23
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 107 7e-23
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 107 7e-23
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 107 7e-23
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 107 7e-23
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 107 7e-23
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 107 7e-23
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 107 7e-23
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 107 9e-23
BC093824-1|AAH93824.1| 422|Homo sapiens serine/threonine/tyrosi... 107 9e-23
BC093822-1|AAH93822.1| 422|Homo sapiens serine/threonine/tyrosi... 107 9e-23
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 107 9e-23
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 107 9e-23
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 107 9e-23
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 107 9e-23
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 107 1e-22
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 106 2e-22
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 105 3e-22
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 105 3e-22
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 105 3e-22
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 105 3e-22
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 105 3e-22
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 105 3e-22
AY563054-1|AAT01226.1| 422|Homo sapiens tyrosine kinase protein... 105 3e-22
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 105 3e-22
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 105 3e-22
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 105 5e-22
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 105 5e-22
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 105 5e-22
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 105 5e-22
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 105 5e-22
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 105 5e-22
AF251059-1|AAK34949.1| 422|Homo sapiens kinase domain protein p... 105 5e-22
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 105 5e-22
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 104 7e-22
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 104 7e-22
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 104 7e-22
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 104 7e-22
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 104 7e-22
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 104 7e-22
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 104 9e-22
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 103 1e-21
>BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein.
Length = 395
Score = 324 bits (795), Expect = 6e-88
Identities = 147/296 (49%), Positives = 201/296 (67%), Gaps = 9/296 (3%)
Query: 222 RIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEA--REQEVLVKTVAEHASQVQVSLL 279
++ ++ I R R+ L+ V EGTFGR++ G DE+ +E++ VKTV + AS++QV+++
Sbjct: 107 KVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMM 166
Query: 280 LQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXX 339
L E C L GLHH +L + V IE+ P ++ P+ W N+KLFL C+ V
Sbjct: 167 LTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPY-MNWGNLKLFLRQCKLVE------A 219
Query: 340 XXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLF 399
++ Q +V MA+ G+ YL + V+HKD+AARNC++D+ L+V I DNALSRDLF
Sbjct: 220 NNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLF 279
Query: 400 PADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEV 459
P DYHCLGDNENRP++W+ALE+L +FS A+DVWA GV LWEL TL PY ++DPFE+
Sbjct: 280 PMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEM 339
Query: 460 AAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLTRFV 515
AAYL+DGYR+ QP NCPDELFAVMA CWA+ P++RP QL L +FH L +V
Sbjct: 340 AAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV 395
>X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase
protein.
Length = 577
Score = 322 bits (791), Expect = 2e-87
Identities = 146/296 (49%), Positives = 201/296 (67%), Gaps = 9/296 (3%)
Query: 222 RIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEA--REQEVLVKTVAEHASQVQVSLL 279
++ ++ I R R+ L+ V EGTFGR++ G DE+ ++++ VKTV + AS++QV+++
Sbjct: 289 KVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKKKQAFVKTVKDQASEIQVTMM 348
Query: 280 LQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXX 339
L E C L GLHH +L + V IE+ P ++ P+ W N+KLFL C+ V
Sbjct: 349 LTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPY-MNWGNLKLFLRQCKLVE------A 401
Query: 340 XXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLF 399
++ Q +V MA+ G+ YL + V+HKD+AARNC++D+ L+V I DNALSRDLF
Sbjct: 402 NNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLF 461
Query: 400 PADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEV 459
P DYHCLGDNENRP++W+ALE+L +FS A+DVWA GV LWEL TL PY ++DPFE+
Sbjct: 462 PMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEM 521
Query: 460 AAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLTRFV 515
AAYL+DGYR+ QP NCPDELFAVMA CWA+ P++RP QL L +FH L +V
Sbjct: 522 AAYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV 577
Score = 90.2 bits (214), Expect = 2e-17
Identities = 51/123 (41%), Positives = 75/123 (60%), Gaps = 5/123 (4%)
Query: 4 GLTAELFYVRDGQINVYALNFVVPVPATINELHFTWQSLTRKPLPYTLSAEVKSNSEAMH 63
GL AEL+YVR+ I+ YAL+F + VP+ N LHFTW + + + Y L +V N AM
Sbjct: 48 GLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHA--KSKVEYKLGFQV-DNVLAMD 104
Query: 64 PPTFNISNEGYVPTEPQTWRVDLPCMRTIAAEVDLTISLNVSTGSSS--TTLHFRRKKIC 121
P NIS +G VP +RV+L C + +EV + + LN++ SS T L+F+R+K+C
Sbjct: 105 MPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMC 164
Query: 122 LKE 124
K+
Sbjct: 165 YKK 167
>X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein.
Length = 607
Score = 319 bits (783), Expect = 2e-86
Identities = 145/295 (49%), Positives = 198/295 (67%), Gaps = 9/295 (3%)
Query: 223 IAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEA--REQEVLVKTVAEHASQVQVSLLL 280
+ ++ I R R+ L+ V EGTFGR++ G DE+ +E++ VKTV + AS++QV+++L
Sbjct: 320 VKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMML 379
Query: 281 QEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXX 340
E C L GLHH +L + V IE+ P ++ P+ W N+KLFL C+ V
Sbjct: 380 TESCKLRGLHHRNLLPITHVCIEEGEKPMVILPY-MNWGNLKLFLRQCKLVE------AN 432
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
++ +V M + G+ YL + V+HKD+AARNC++D+ L+V I DNALSRDLFP
Sbjct: 433 NPQAISQHDLVHMPIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFP 492
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DYHCLGDNENRP++W+ALE+L +FS A+DVWA GV LWEL TL PY ++DPFE+A
Sbjct: 493 MDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMA 552
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLTRFV 515
AYL+DGYR+ QP NCPDELFAVMA CWA+ P++RP QL L +FH L +V
Sbjct: 553 AYLKDGYRIAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV 607
Score = 90.2 bits (214), Expect = 2e-17
Identities = 51/123 (41%), Positives = 75/123 (60%), Gaps = 5/123 (4%)
Query: 4 GLTAELFYVRDGQINVYALNFVVPVPATINELHFTWQSLTRKPLPYTLSAEVKSNSEAMH 63
GL AEL+YVR+ I+ YAL+F + VP+ N LHFTW + + + Y L +V N AM
Sbjct: 78 GLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHA--KSKVEYKLGFQV-DNVLAMD 134
Query: 64 PPTFNISNEGYVPTEPQTWRVDLPCMRTIAAEVDLTISLNVSTGSSS--TTLHFRRKKIC 121
P NIS +G VP +RV+L C + +EV + + LN++ SS T L+F+R+K+C
Sbjct: 135 MPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMC 194
Query: 122 LKE 124
K+
Sbjct: 195 YKK 197
>S59184-1|AAB26341.1| 606|Homo sapiens RYK protein.
Length = 606
Score = 312 bits (766), Expect = 2e-84
Identities = 146/298 (48%), Positives = 200/298 (67%), Gaps = 11/298 (3%)
Query: 222 RIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEA--REQEVLVKTVAEHASQVQVSLL 279
++ ++ I R R+ L+ V EGTFGR++ G DE+ +E++ VKTV + AS++QV+++
Sbjct: 316 KVKDIAISRERITLKDVLQEGTFGRIFHGILIDEKDPNKEKQAFVKTVKDQASEIQVTMM 375
Query: 280 LQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXX 339
L E C L GLHH +L + V IE+ P ++ P+ W N+KLFL C+ V
Sbjct: 376 LTESCKLRGLHHRNLLPITHVCIEEGEKPMVILPY-MNWGNLKLFLRQCKLVE------A 428
Query: 340 XXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLF 399
++ Q +V MA+ G+ YL + V+HKD+AARNC++D+ L+V I DNALSRDLF
Sbjct: 429 NNPQAISQQDLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLF 488
Query: 400 PADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGV-LLWELTTLAHQPYA-EVDPF 457
P DYHCLGDNENRP++W+ALE+L +FS A+DVWA GV LWEL TL PY ++DPF
Sbjct: 489 PMDYHCLGDNENRPVRWMALESLVNNEFSSASDVWAFGVNSLWELMTLGQTPYTLDIDPF 548
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLTRFV 515
E+AAYL+DGYR+ QP CPDELFAVMA CWA+ P++RP QL L +FH L +V
Sbjct: 549 EMAAYLKDGYRIAQPITCPDELFAVMACCWALDPEERPRFQQLVQCLTEFHAALGAYV 606
Score = 90.2 bits (214), Expect = 2e-17
Identities = 51/123 (41%), Positives = 75/123 (60%), Gaps = 5/123 (4%)
Query: 4 GLTAELFYVRDGQINVYALNFVVPVPATINELHFTWQSLTRKPLPYTLSAEVKSNSEAMH 63
GL AEL+YVR+ I+ YAL+F + VP+ N LHFTW + + + Y L +V N AM
Sbjct: 75 GLDAELYYVRNDLISHYALSFNLLVPSETNFLHFTWHA--KSKVEYKLGFQV-DNVLAMD 131
Query: 64 PPTFNISNEGYVPTEPQTWRVDLPCMRTIAAEVDLTISLNVSTGSSS--TTLHFRRKKIC 121
P NIS +G VP +RV+L C + +EV + + LN++ SS T L+F+R+K+C
Sbjct: 132 MPQVNISVQGEVPRTLSVFRVELSCTGKVDSEVMILMQLNLTVNSSKNFTVLNFKRRKMC 191
Query: 122 LKE 124
K+
Sbjct: 192 YKK 194
>AB209405-1|BAD92642.1| 232|Homo sapiens RYK receptor-like tyrosine
kinase isoform 1 variant protein.
Length = 232
Score = 258 bits (632), Expect = 3e-68
Identities = 117/227 (51%), Positives = 154/227 (67%), Gaps = 7/227 (3%)
Query: 289 LHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQ 348
L + +L + V IE+ P ++ P+ W N+KLFL C+ V ++ Q
Sbjct: 13 LFYRNLLPITHVCIEEGEKPMVILPY-MNWGNLKLFLRQCKLVE------ANNPQAISQQ 65
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+V MA+ G+ YL + V+HKD+AARNC++D+ L+V I DNALSRDLFP DYHCLGD
Sbjct: 66 DLVHMAIQIACGMSYLARREVIHKDLAARNCVIDDTLQVKITDNALSRDLFPMDYHCLGD 125
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
NENRP++W+ALE+L +FS A+DVWA GV LWEL TL PY ++DPFE+AAYL+DGYR
Sbjct: 126 NENRPVRWMALESLVNNEFSSASDVWAFGVTLWELMTLGQTPYVDIDPFEMAAYLKDGYR 185
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLTRFV 515
+ QP NCPDELFAVMA CWA+ P++RP QL L +FH L +V
Sbjct: 186 IAQPINCPDELFAVMACCWALDPEERPKFQQLVQCLTEFHAALGAYV 232
>X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein.
Length = 1400
Score = 188 bits (457), Expect = 5e-47
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 23/319 (7%)
Query: 187 LPDSSCKSGASYTSYRRPTSLPAVAAEE-RARDLQQ----RIAELTIQRCRVRLRS--VA 239
L ++C GAS++ + +P + E + RDL + ++ I RV S V
Sbjct: 1029 LDSTTCVHGASFSDSEDESCVPLLRKESIQLRDLDSALLAEVKDVLIPHERVVTHSDRVI 1088
Query: 240 MEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
+G FG VY G Y D+ + +K+++ QV L+EG ++ GL+H VL+++G
Sbjct: 1089 GKGHFGVVYHGEYIDQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIG 1148
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALD 359
+ + + P +L P+ C G + T + ++ L
Sbjct: 1149 IMLPPEGLPHVLLPY------------MCHGDLLQFIRSPQRNP--TVKDLISFGLQVAR 1194
Query: 360 GLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR--PIKWL 417
G+ YL Q +H+D+AARNC++DE+ V +AD L+RD+ +Y+ + + + P+KW+
Sbjct: 1195 GMEYLAEQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWM 1254
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
ALE+L +F+ +DVW+ GVLLWEL T PY +DPF++ +L G RL QP CPD
Sbjct: 1255 ALESLQTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPD 1314
Query: 478 ELFAVMAYCWAMSPDDRPT 496
L+ VM CW P RPT
Sbjct: 1315 SLYQVMQQCWEADPAVRPT 1333
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 171 bits (416), Expect = 5e-42
Identities = 94/294 (31%), Positives = 159/294 (54%), Gaps = 14/294 (4%)
Query: 216 ARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQV 274
+ +LQ ++ ++ I R + L + EG FG V G E+ +V VKT+ +++SQ
Sbjct: 394 SEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQR 453
Query: 275 QVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTA----PFLLYPWDAGWRNMKLFLLACRG 330
++ L E + H V+ +LGV IE + P ++ P+ + ++ +LL R
Sbjct: 454 EIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF-MKYGDLHTYLLYSRL 512
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
T + Q +++ + G+ YL +++ LH+D+AARNC++ +++ V +A
Sbjct: 513 ET--------GPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 564
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D LS+ ++ DY+ G P+KW+A+E+L R ++ +DVWA GV +WE+ T P
Sbjct: 565 DFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTP 624
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
Y V E+ YL G+RL+QP +C DEL+ +M CW P DRPT L++ L
Sbjct: 625 YPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQL 678
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 171 bits (416), Expect = 5e-42
Identities = 94/294 (31%), Positives = 159/294 (54%), Gaps = 14/294 (4%)
Query: 216 ARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQV 274
+ +LQ ++ ++ I R + L + EG FG V G E+ +V VKT+ +++SQ
Sbjct: 394 SEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQR 453
Query: 275 QVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTA----PFLLYPWDAGWRNMKLFLLACRG 330
++ L E + H V+ +LGV IE + P ++ P+ + ++ +LL R
Sbjct: 454 EIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF-MKYGDLHTYLLYSRL 512
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
T + Q +++ + G+ YL +++ LH+D+AARNC++ +++ V +A
Sbjct: 513 ET--------GPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 564
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D LS+ ++ DY+ G P+KW+A+E+L R ++ +DVWA GV +WE+ T P
Sbjct: 565 DFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTP 624
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
Y V E+ YL G+RL+QP +C DEL+ +M CW P DRPT L++ L
Sbjct: 625 YPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQL 678
>AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine
kinase protein.
Length = 978
Score = 171 bits (416), Expect = 5e-42
Identities = 94/294 (31%), Positives = 159/294 (54%), Gaps = 14/294 (4%)
Query: 216 ARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQV 274
+ +LQ ++ ++ I R + L + EG FG V G E+ +V VKT+ +++SQ
Sbjct: 549 SEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQR 608
Query: 275 QVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTA----PFLLYPWDAGWRNMKLFLLACRG 330
++ L E + H V+ +LGV IE + P ++ P+ + ++ +LL R
Sbjct: 609 EIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF-MKYGDLHTYLLYSRL 667
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
T + Q +++ + G+ YL +++ LH+D+AARNC++ +++ V +A
Sbjct: 668 ET--------GPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 719
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D LS+ ++ DY+ G P+KW+A+E+L R ++ +DVWA GV +WE+ T P
Sbjct: 720 DFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTP 779
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
Y V E+ YL G+RL+QP +C DEL+ +M CW P DRPT L++ L
Sbjct: 780 YPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQL 833
>AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein.
Length = 567
Score = 171 bits (416), Expect = 5e-42
Identities = 94/294 (31%), Positives = 159/294 (54%), Gaps = 14/294 (4%)
Query: 216 ARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQV 274
+ +LQ ++ ++ I R + L + EG FG V G E+ +V VKT+ +++SQ
Sbjct: 138 SEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQR 197
Query: 275 QVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTA----PFLLYPWDAGWRNMKLFLLACRG 330
++ L E + H V+ +LGV IE + P ++ P+ + ++ +LL R
Sbjct: 198 EIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF-MKYGDLHTYLLYSRL 256
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
T + Q +++ + G+ YL +++ LH+D+AARNC++ +++ V +A
Sbjct: 257 ET--------GPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 308
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D LS+ ++ DY+ G P+KW+A+E+L R ++ +DVWA GV +WE+ T P
Sbjct: 309 DFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTP 368
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
Y V E+ YL G+RL+QP +C DEL+ +M CW P DRPT L++ L
Sbjct: 369 YPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQL 422
>X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA for
tyrosine kinase receptor. ).
Length = 894
Score = 170 bits (414), Expect = 9e-42
Identities = 96/308 (31%), Positives = 166/308 (53%), Gaps = 16/308 (5%)
Query: 200 SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE 259
SY R T+ + + + +L++++ ++ + R +V L EG FG V G +++
Sbjct: 503 SYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI- 561
Query: 260 QEVLVKTVA-EHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSI-----EDQTAPFLLYP 313
+V VKT+ ++ ++ L E + H V+ ++GV E AP ++ P
Sbjct: 562 LKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILP 621
Query: 314 WDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKD 373
+ ++ FLL R L TQ +V+ G+ YL ++ +H+D
Sbjct: 622 F-MKHGDLHSFLLYSR--------LGGQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD 672
Query: 374 IAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADV 433
+AARNC+++EN+ V +AD LS+ ++ DY+ G P+KW+A+E+L R ++ +DV
Sbjct: 673 LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDV 732
Query: 434 WALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDD 493
W+ GV +WE+ T PY V+ E+ YLR G RL+QPA+C D L+A+M+ CW ++P D
Sbjct: 733 WSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQD 792
Query: 494 RPTLPQLQ 501
RP+ +L+
Sbjct: 793 RPSFTELR 800
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 170 bits (414), Expect = 9e-42
Identities = 91/270 (33%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 211 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 270
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 271 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 316
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L G+ YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 317 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 376
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GVLLWEL T PY +V+ F++ YL G RL
Sbjct: 377 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 436
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 437 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 466
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 170 bits (414), Expect = 9e-42
Identities = 91/270 (33%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 143 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 202
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 203 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 248
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L G+ YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 249 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 308
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GVLLWEL T PY +V+ F++ YL G RL
Sbjct: 309 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 368
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 369 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 398
>S65125-1|AAB20305.1| 894|Homo sapiens UFO protein.
Length = 894
Score = 170 bits (414), Expect = 9e-42
Identities = 96/308 (31%), Positives = 166/308 (53%), Gaps = 16/308 (5%)
Query: 200 SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE 259
SY R T+ + + + +L++++ ++ + R +V L EG FG V G +++
Sbjct: 503 SYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI- 561
Query: 260 QEVLVKTVA-EHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSI-----EDQTAPFLLYP 313
+V VKT+ ++ ++ L E + H V+ ++GV E AP ++ P
Sbjct: 562 LKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILP 621
Query: 314 WDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKD 373
+ ++ FLL R L TQ +V+ G+ YL ++ +H+D
Sbjct: 622 F-MKHGDLHSFLLYSR--------LGGQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD 672
Query: 374 IAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADV 433
+AARNC+++EN+ V +AD LS+ ++ DY+ G P+KW+A+E+L R ++ +DV
Sbjct: 673 LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDV 732
Query: 434 WALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDD 493
W+ GV +WE+ T PY V+ E+ YLR G RL+QPA+C D L+A+M+ CW ++P D
Sbjct: 733 WSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQD 792
Query: 494 RPTLPQLQ 501
RP+ +L+
Sbjct: 793 RPSFTELR 800
>M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor
protein.
Length = 885
Score = 170 bits (414), Expect = 9e-42
Identities = 96/308 (31%), Positives = 166/308 (53%), Gaps = 16/308 (5%)
Query: 200 SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE 259
SY R T+ + + + +L++++ ++ + R +V L EG FG V G +++
Sbjct: 494 SYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI- 552
Query: 260 QEVLVKTVA-EHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSI-----EDQTAPFLLYP 313
+V VKT+ ++ ++ L E + H V+ ++GV E AP ++ P
Sbjct: 553 LKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILP 612
Query: 314 WDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKD 373
+ ++ FLL R L TQ +V+ G+ YL ++ +H+D
Sbjct: 613 F-MKHGDLHSFLLYSR--------LGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD 663
Query: 374 IAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADV 433
+AARNC+++EN+ V +AD LS+ ++ DY+ G P+KW+A+E+L R ++ +DV
Sbjct: 664 LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDV 723
Query: 434 WALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDD 493
W+ GV +WE+ T PY V+ E+ YLR G RL+QPA+C D L+A+M+ CW ++P D
Sbjct: 724 WSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPADCLDGLYALMSRCWELNPQD 783
Query: 494 RPTLPQLQ 501
RP+ +L+
Sbjct: 784 RPSFTELR 791
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 170 bits (414), Expect = 9e-42
Identities = 91/270 (33%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 1078 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 1138 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 1183
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L G+ YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GVLLWEL T PY +V+ F++ YL G RL
Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene
precursor variant protein.
Length = 712
Score = 170 bits (414), Expect = 9e-42
Identities = 91/270 (33%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 400 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 459
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 460 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 505
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L G+ YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 506 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 565
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GVLLWEL T PY +V+ F++ YL G RL
Sbjct: 566 KLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 625
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 626 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 655
>BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine
kinase protein.
Length = 894
Score = 169 bits (412), Expect = 2e-41
Identities = 96/308 (31%), Positives = 166/308 (53%), Gaps = 16/308 (5%)
Query: 200 SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE 259
SY R T+ + + + +L++++ ++ + R +V L EG FG V G +++
Sbjct: 503 SYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSI- 561
Query: 260 QEVLVKTVA-EHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSI-----EDQTAPFLLYP 313
+V VKT+ ++ ++ L E + H V+ ++GV E AP ++ P
Sbjct: 562 LKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSERESFPAPVVILP 621
Query: 314 WDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKD 373
+ ++ FLL R L TQ +V+ G+ YL ++ +H+D
Sbjct: 622 F-MKHGDLHSFLLYSR--------LGDQPVYLPTQMLVKFMADIASGMEYLSTKRFIHRD 672
Query: 374 IAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADV 433
+AARNC+++EN+ V +AD LS+ ++ DY+ G P+KW+A+E+L R ++ +DV
Sbjct: 673 LAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDV 732
Query: 434 WALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDD 493
W+ GV +WE+ T PY V+ E+ YLR G RL+QPA+C D L+A+M+ CW ++P D
Sbjct: 733 WSFGVTMWEIATRGQTPYPGVENSEIYDYLRRGNRLKQPADCLDGLYALMSRCWELNPQD 792
Query: 494 RPTLPQLQ 501
RP+ +L+
Sbjct: 793 RPSFTELR 800
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 169 bits (411), Expect = 2e-41
Identities = 90/270 (33%), Positives = 145/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 1078 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1137
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 1138 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 1183
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L G+ YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 1184 FGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1243
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GV+LWEL T PY +V+ F++ YL G RL
Sbjct: 1244 KLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1303
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 1304 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein.
Length = 999
Score = 169 bits (410), Expect = 3e-41
Identities = 93/294 (31%), Positives = 158/294 (53%), Gaps = 14/294 (4%)
Query: 216 ARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQV 274
+ +LQ ++ ++ I R + L + EG FG V G E+ +V VKT+ +++S
Sbjct: 570 SEELQNKLEDVVIDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSHR 629
Query: 275 QVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTA----PFLLYPWDAGWRNMKLFLLACRG 330
++ L E + H V+ +LGV IE + P ++ P+ + ++ +LL R
Sbjct: 630 EIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPF-MKYGDLHTYLLYSRL 688
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
T + Q +++ + G+ YL +++ LH+D+AARNC++ +++ V +A
Sbjct: 689 ET--------GPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVA 740
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D LS+ ++ DY+ G P+KW+A+E+L R ++ +DVWA GV +WE+ T P
Sbjct: 741 DFGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTP 800
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
Y V E+ YL G+RL+QP +C DEL+ +M CW P DRPT L++ L
Sbjct: 801 YPGVQNHEMYDYLLHGHRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQL 854
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 167 bits (405), Expect = 1e-40
Identities = 89/270 (32%), Positives = 144/270 (53%), Gaps = 16/270 (5%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHE 292
V V G FG VY GT D + ++ VK++ +VS L EG ++ H
Sbjct: 1096 VHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHP 1155
Query: 293 RVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVR 352
VLS+LG+ + + +P ++ P+ +++ F+ R T T + ++
Sbjct: 1156 NVLSLLGICLRSEGSPLVVLPY-MKHGDLRNFI---RNET----------HNPTVKDLIG 1201
Query: 353 MALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENR 412
L + YL S+ +H+D+AARNC++DE V +AD L+RD++ +Y+ + +
Sbjct: 1202 FGLQVAKAMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGA 1261
Query: 413 --PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
P+KW+ALE+L ++F+ +DVW+ GV+LWEL T PY +V+ F++ YL G RL
Sbjct: 1262 KLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLL 1321
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
QP CPD L+ VM CW + RP+ +L
Sbjct: 1322 QPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1351
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 163 bits (397), Expect = 1e-39
Identities = 93/284 (32%), Positives = 151/284 (53%), Gaps = 8/284 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ L +G+FG VY G D + E V VKTV E AS + L E
Sbjct: 1003 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 1062
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ G V+ +LGV + Q P L+ ++K +L + R
Sbjct: 1063 ASVMKGFTCHHVVRLLGVVSKGQ--PTLVVMELMAHGDLKSYLRSLRP----EAENNPGR 1116
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
T Q +++MA DG+ YL+++ +H+D+AARNC+V + V I D ++RD++ D
Sbjct: 1117 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1176
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W+A E+L F+ ++D+W+ GV+LWE+T+LA QPY + +V +
Sbjct: 1177 YYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1236
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
+ DG L QP NCP+ + +M CW +P+ RPT ++ L+D
Sbjct: 1237 VMDGGYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLKD 1280
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 163 bits (395), Expect = 2e-39
Identities = 93/284 (32%), Positives = 150/284 (52%), Gaps = 8/284 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ L +G+FG VY G D + E V VKTV E AS + L E
Sbjct: 1015 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 1074
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ G V+ +LGV + Q P L+ ++K +L + R
Sbjct: 1075 ASVMKGFTCHHVVRLLGVVSKGQ--PTLVVMELMAHGDLKSYLRSLRP----EAENNPGR 1128
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
T Q +++MA DG+ YL+++ +H+D+AARNC+V + V I D ++RD++ D
Sbjct: 1129 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1188
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W+A E+L F+ ++D+W+ GV+LWE+T+LA QPY + +V +
Sbjct: 1189 YYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1248
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
+ DG L QP NCP+ + +M CW +P RPT ++ L+D
Sbjct: 1249 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKD 1292
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 163 bits (395), Expect = 2e-39
Identities = 93/284 (32%), Positives = 150/284 (52%), Gaps = 8/284 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ L +G+FG VY G D + E V VKTV E AS + L E
Sbjct: 1015 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 1074
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ G V+ +LGV + Q P L+ ++K +L + R
Sbjct: 1075 ASVMKGFTCHHVVRLLGVVSKGQ--PTLVVMELMAHGDLKSYLRSLRP----EAENNPGR 1128
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
T Q +++MA DG+ YL+++ +H+D+AARNC+V + V I D ++RD++ D
Sbjct: 1129 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1188
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W+A E+L F+ ++D+W+ GV+LWE+T+LA QPY + +V +
Sbjct: 1189 YYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1248
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
+ DG L QP NCP+ + +M CW +P RPT ++ L+D
Sbjct: 1249 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKD 1292
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 163 bits (395), Expect = 2e-39
Identities = 93/284 (32%), Positives = 150/284 (52%), Gaps = 8/284 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ L +G+FG VY G D + E V VKTV E AS + L E
Sbjct: 1003 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 1062
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ G V+ +LGV + Q P L+ ++K +L + R
Sbjct: 1063 ASVMKGFTCHHVVRLLGVVSKGQ--PTLVVMELMAHGDLKSYLRSLRP----EAENNPGR 1116
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
T Q +++MA DG+ YL+++ +H+D+AARNC+V + V I D ++RD++ D
Sbjct: 1117 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 1176
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W+A E+L F+ ++D+W+ GV+LWE+T+LA QPY + +V +
Sbjct: 1177 YYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 1236
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
+ DG L QP NCP+ + +M CW +P RPT ++ L+D
Sbjct: 1237 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKD 1280
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 163 bits (395), Expect = 2e-39
Identities = 93/284 (32%), Positives = 150/284 (52%), Gaps = 8/284 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ L +G+FG VY G D + E V VKTV E AS + L E
Sbjct: 466 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 525
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ G V+ +LGV + Q P L+ ++K +L + R
Sbjct: 526 ASVMKGFTCHHVVRLLGVVSKGQ--PTLVVMELMAHGDLKSYLRSLRP----EAENNPGR 579
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
T Q +++MA DG+ YL+++ +H+D+AARNC+V + V I D ++RD++ D
Sbjct: 580 PPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD 639
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W+A E+L F+ ++D+W+ GV+LWE+T+LA QPY + +V +
Sbjct: 640 YYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKF 699
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
+ DG L QP NCP+ + +M CW +P RPT ++ L+D
Sbjct: 700 VMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKD 743
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 1925 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 1984
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 1985 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 2042
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 2043 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 2095
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 2096 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2155
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 2156 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2212
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 1931 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 1990
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 1991 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 2048
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 2049 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 2101
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 2102 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2161
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 2162 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 1931 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 1990
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 1991 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 2048
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 2049 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 2101
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 2102 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2161
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 2162 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQNQLQLF 2218
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 78 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 137
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 138 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 195
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 196 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 248
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 249 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 308
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 309 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 365
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 142 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 201
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 202 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 259
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 260 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 312
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 313 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 372
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 373 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 429
>AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 1931 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 1990
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 1991 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 2048
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 2049 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 2101
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 2102 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2161
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 2162 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2218
>AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 160 bits (388), Expect = 1e-38
Identities = 96/297 (32%), Positives = 155/297 (52%), Gaps = 18/297 (6%)
Query: 220 QQRIAEL-TIQRCRVRLRSVAMEGTFGRVYRGTYAD---EEAREQEVLVKTVAEHASQVQ 275
Q+ I L R ++ LR + G FG VY GT D + E +V VKT+ + ++ +
Sbjct: 1925 QEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQE 1984
Query: 276 VSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX 335
L+E ++ +H +L LGV + ++ +L + G ++ +L R T
Sbjct: 1985 KIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGG--DLLTYLRKARMATFYG 2042
Query: 336 XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD----ENLRVM-IA 390
LT +V + + G +YL H +H+D+AARNC+V + R++ I
Sbjct: 2043 PL-------LTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIG 2095
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D L+RD++ DY+ P++W+A E+L F+ +DVW+ G+L+WE+ TL HQP
Sbjct: 2096 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQP 2155
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
Y +V Y++ G RL+ P NCPD+L+ +M CWA PD RPT ++Q L+ F
Sbjct: 2156 YPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQLF 2212
>M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein.
Length = 731
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 392 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 451
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 452 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 509
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 510 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 569
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 570 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 629
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 630 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 669
>M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor
receptor protein.
Length = 806
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 467 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 526
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 527 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 584
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 585 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 644
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 645 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 704
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 705 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744
>BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 141 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 200
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 201 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 258
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 259 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 318
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 319 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 378
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 379 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 418
>BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 141 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 200
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 201 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 258
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 259 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 318
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 319 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 378
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 379 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 418
>AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth factor
receptor 3 (achondroplasia, thanatophoric dwarfism)
protein.
Length = 806
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 467 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 526
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 527 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 584
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 585 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 644
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 645 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 704
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 705 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744
>AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 769
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 430 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 489
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 490 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 547
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 548 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 607
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 608 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 667
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 668 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 707
>AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 771
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 432 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 491
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 492 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 549
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 550 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 609
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 610 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 669
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 670 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 709
>AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 694
Score = 157 bits (382), Expect = 7e-38
Identities = 96/280 (34%), Positives = 146/280 (52%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D A+ V VK + + A+ +S L+ E
Sbjct: 355 LSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEM 414
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG Q P + A N++ FL A R G+
Sbjct: 415 EMMKMIGKHKNIINLLGACT--QGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKP 472
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
LT + +V A G+ YL SQ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 473 PEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHN 532
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY + E+
Sbjct: 533 LDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELF 592
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +PANC +L+ +M CW +P RPT QL
Sbjct: 593 KLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 632
>BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 155 bits (376), Expect = 4e-37
Identities = 89/301 (29%), Positives = 156/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E++ +V VK + A+ + +
Sbjct: 503 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDSSFVKVAVKMLKADIIASSDI 562
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 563 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 619
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 620 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 673
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 674 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 733
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 734 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 793
Query: 512 T 512
+
Sbjct: 794 S 794
>U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase
protein.
Length = 882
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 495 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 554
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 555 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 611
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 612 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 665
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 666 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 725
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 726 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 785
Query: 512 T 512
+
Sbjct: 786 S 786
>U05682-1|AAA19236.1| 890|Homo sapiens Rse protein.
Length = 890
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 503 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 562
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 563 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 619
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 620 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 673
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 674 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 733
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 734 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 793
Query: 512 T 512
+
Sbjct: 794 S 794
>D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase
protein.
Length = 884
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 497 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 556
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 557 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 613
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 614 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 667
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 668 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 727
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 728 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 787
Query: 512 T 512
+
Sbjct: 788 S 788
>D17517-1|BAA04467.1| 890|Homo sapiens Sky protein.
Length = 890
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 503 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 562
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 563 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 619
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 620 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 673
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 674 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 733
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 734 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 793
Query: 512 T 512
+
Sbjct: 794 S 794
>BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine
kinase protein.
Length = 890
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 503 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 562
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 563 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 619
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 620 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 673
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 674 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 733
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 734 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 793
Query: 512 T 512
+
Sbjct: 794 S 794
>BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein.
Length = 518
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 131 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 190
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 191 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 247
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 248 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 301
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 302 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 361
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 362 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 421
Query: 512 T 512
+
Sbjct: 422 S 422
>AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine
kinase variant protein.
Length = 951
Score = 155 bits (375), Expect = 5e-37
Identities = 89/301 (29%), Positives = 155/301 (51%), Gaps = 15/301 (4%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 564 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 623
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 624 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 680
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 681 ------IGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 734
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 735 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 794
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G RL+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 795 AGIENAEIYNYLIGGNRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 854
Query: 512 T 512
+
Sbjct: 855 S 855
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 607
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 664
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 665 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 724
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 785 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 825
>AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 607
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 664
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 665 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 724
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 785 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 825
>AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 607
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 664
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 665 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 724
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 785 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 825
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 549 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 607
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 608 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 664
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 665 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 724
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 725 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 784
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 785 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 825
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine
kinase receptor type 2 protein.
Length = 822
Score = 153 bits (372), Expect = 1e-36
Identities = 86/281 (30%), Positives = 144/281 (51%), Gaps = 6/281 (2%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLV--KTVAEHASQVQVSLLLQEGCM 285
I+R + L+ EG FG+V+ + + ++LV KT+ + + + +E +
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFH-REAEL 591
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
L L HE ++ GV +E + G ++ FL A G L
Sbjct: 592 LTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHG--DLNKFLRA-HGPDAVLMAEGNPPTEL 648
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
T ++ +A G++YL SQH +H+D+A RNC+V ENL V I D +SRD++ DY+
Sbjct: 649 TQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYR 708
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G + PI+W+ E++ R+F+ +DVW+LGV+LWE+ T QP+ ++ EV +
Sbjct: 709 VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQ 768
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
G LQ+P CP E++ +M CW P R + + L++
Sbjct: 769 GRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQN 809
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 273 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 332
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 333 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 390
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 391 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 450
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 451 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 510
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 511 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 550
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 382 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 441
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 442 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 499
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 500 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 559
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 560 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 619
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 620 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 659
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 384 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 443
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 444 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 501
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 502 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 561
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 562 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 621
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 622 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 661
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 152 bits (369), Expect = 2e-36
Identities = 85/278 (30%), Positives = 145/278 (52%), Gaps = 8/278 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ + +G+FG VY G ++ E V +KTV E AS + L E
Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE 1050
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ + V+ +LGV + Q ++ G ++K +L + R
Sbjct: 1051 ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRG--DLKSYLRSLRP----EMENNPVL 1104
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
+ +++MA DG+ YL++ +H+D+AARNC+V E+ V I D ++RD++ D
Sbjct: 1105 APPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETD 1164
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W++ E+L F+ +DVW+ GV+LWE+ TLA QPY + +V +
Sbjct: 1165 YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF 1224
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ +G L +P NCPD LF +M CW +P RP+ ++
Sbjct: 1225 VMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 382 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 441
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 442 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 499
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 500 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 559
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 560 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 619
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 620 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 659
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 382 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 441
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 442 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 499
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 500 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 559
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 560 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 619
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 620 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 659
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 384 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 443
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 444 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 501
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 502 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 561
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 562 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 621
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 622 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 661
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 152 bits (369), Expect = 2e-36
Identities = 85/278 (30%), Positives = 145/278 (52%), Gaps = 8/278 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ + +G+FG VY G ++ E V +KTV E AS + L E
Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE 1050
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ + V+ +LGV + Q ++ G ++K +L + R
Sbjct: 1051 ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRG--DLKSYLRSLRP----EMENNPVL 1104
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
+ +++MA DG+ YL++ +H+D+AARNC+V E+ V I D ++RD++ D
Sbjct: 1105 APPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETD 1164
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W++ E+L F+ +DVW+ GV+LWE+ TLA QPY + +V +
Sbjct: 1165 YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF 1224
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ +G L +P NCPD LF +M CW +P RP+ ++
Sbjct: 1225 VMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 152 bits (369), Expect = 2e-36
Identities = 85/278 (30%), Positives = 145/278 (52%), Gaps = 8/278 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ + +G+FG VY G ++ E V +KTV E AS + L E
Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE 1050
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ + V+ +LGV + Q ++ G ++K +L + R
Sbjct: 1051 ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRG--DLKSYLRSLRP----EMENNPVL 1104
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
+ +++MA DG+ YL++ +H+D+AARNC+V E+ V I D ++RD++ D
Sbjct: 1105 APPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETD 1164
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W++ E+L F+ +DVW+ GV+LWE+ TLA QPY + +V +
Sbjct: 1165 YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF 1224
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ +G L +P NCPD LF +M CW +P RP+ ++
Sbjct: 1225 VMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 382 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 441
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 442 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 499
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 500 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 559
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 560 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 619
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 620 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 659
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 473 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 532
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 533 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 590
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 591 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 650
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 651 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 710
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 711 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 152 bits (369), Expect = 2e-36
Identities = 85/278 (30%), Positives = 145/278 (52%), Gaps = 8/278 (2%)
Query: 225 ELTIQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQE 282
E + R ++ + +G+FG VY G ++ E V +KTV E AS + L E
Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE 1050
Query: 283 GCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXX 342
++ + V+ +LGV + Q ++ G ++K +L + R
Sbjct: 1051 ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRG--DLKSYLRSLRP----EMENNPVL 1104
Query: 343 XXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPAD 402
+ +++MA DG+ YL++ +H+D+AARNC+V E+ V I D ++RD++ D
Sbjct: 1105 APPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETD 1164
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ G P++W++ E+L F+ +DVW+ GV+LWE+ TLA QPY + +V +
Sbjct: 1165 YYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRF 1224
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ +G L +P NCPD LF +M CW +P RP+ ++
Sbjct: 1225 VMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262
>AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth factor
receptor 1 isoform 2 precursor variant protein.
Length = 820
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 471 LPRDRLVLGRPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 530
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 531 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQAWRPPGLEYCYNPSHN 588
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 589 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 648
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 649 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 708
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 709 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 748
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 424 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 482
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 483 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 542
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 543 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 600
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 601 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 660
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 661 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 720
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 721 LMRECWHAAPSQRPTFKQL 739
>AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth factor
receptor 4 variant protein.
Length = 592
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 214 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 272
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 273 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 332
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 333 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 390
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 391 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 450
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 451 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 510
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 511 LMRECWHAAPSQRPTFKQL 529
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 384 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 442
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 443 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 502
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 503 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 560
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 561 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 620
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 621 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 680
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 681 LMRECWHAAPSQRPTFKQL 699
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 152 bits (369), Expect = 2e-36
Identities = 104/319 (32%), Positives = 165/319 (51%), Gaps = 11/319 (3%)
Query: 190 SSCKSGASYT-SYRRPTSLPAVAAEERARDLQQRIAELTIQRCRVRLRSVAMEGTFGRVY 248
SS KS +S R +S PA+ A + DL R R+ L EG FG+V
Sbjct: 656 SSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPL-WEFPRDRLVLGKPLGEGCFGQVV 714
Query: 249 RG-TYADEEAREQE---VLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLGVSIE 303
R + + AR + V VK + ++AS ++ L+ E ++ + H+ ++++LGV +
Sbjct: 715 RAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQ 774
Query: 304 DQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ P + A N++ FL A R G + L+ +V A G+
Sbjct: 775 E--GPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM 832
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL S+ +H+D+AARN +V E+ + IAD L+R + DY+ N P+KW+A EA
Sbjct: 833 QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA 892
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L R ++ +DVW+ G+LLWE+ TL PY + E+ + LR+G+R+ +P +CP EL+
Sbjct: 893 LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG 952
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P RPT QL
Sbjct: 953 LMRECWHAAPSQRPTFKQL 971
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 152 bits (369), Expect = 2e-36
Identities = 94/280 (33%), Positives = 149/280 (53%), Gaps = 9/280 (3%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEG 283
+ R R+ L EG FG+V G D+ R +V VK + A++ +S L+ E
Sbjct: 465 LPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEM 524
Query: 284 CMLYGL-HHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXX 340
M+ + H+ ++++LG +D P + A N++ +L A R G+
Sbjct: 525 EMMKMIGKHKNIINLLGACTQD--GPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHN 582
Query: 341 XXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFP 400
L+++ +V A G+ YL S+ +H+D+AARN +V E+ + IAD L+RD+
Sbjct: 583 PEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHH 642
Query: 401 ADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVA 460
DY+ N P+KW+A EAL R ++ +DVW+ GVLLWE+ TL PY V E+
Sbjct: 643 IDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELF 702
Query: 461 AYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++G+R+ +P+NC +EL+ +M CW P RPT QL
Sbjct: 703 KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 742
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 489 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 548
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 549 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 606
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 607 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 666
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 667 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 726
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQL 753
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 489 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 548
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 549 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 606
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 607 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 666
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 667 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 726
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQL 753
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 373 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 432
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 433 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 490
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 491 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 550
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 551 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 610
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 611 NCTNELYMMMRDCWHAVPSQRPTFKQL 637
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 489 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 548
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 549 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 606
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 607 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 666
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 667 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 726
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 727 NCTNELYMMMRDCWHAVPSQRPTFKQL 753
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 399 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 458
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 459 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 516
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 517 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 576
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 577 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 636
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 637 NCTNELYMMMRDCWHAVPSQRPTFKQL 663
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 487 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 546
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 547 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 604
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 605 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 664
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 665 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 724
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 725 NCTNELYMMMRDCWHAVPSQRPTFKQL 751
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 372 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 431
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 432 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 489
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 490 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 549
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 550 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 609
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 610 NCTNELYMMMRDCWHAVPSQRPTFKQL 636
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 487 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 546
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 547 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 604
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 605 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 664
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 665 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 724
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 725 NCTNELYMMMRDCWHAVPSQRPTFKQL 751
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 487 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 546
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 547 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 604
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 605 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 664
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 665 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 724
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 725 NCTNELYMMMRDCWHAVPSQRPTFKQL 751
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 487 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 546
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 547 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 604
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 605 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 664
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 665 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 724
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 725 NCTNELYMMMRDCWHAVPSQRPTFKQL 751
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 488 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 547
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 548 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 605
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 606 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 665
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 666 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 725
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 726 NCTNELYMMMRDCWHAVPSQRPTFKQL 752
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 276 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 335
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 336 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 393
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 394 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 453
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 454 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 513
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 514 NCTNELYMMMRDCWHAVPSQRPTFKQL 540
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor
2 IgIIIb isoform protein.
Length = 555
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 277 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 336
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 337 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 394
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 395 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 454
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 455 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 514
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 515 NCTNELYMMMRDCWHAVPSQRPTFKQL 541
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 151 bits (367), Expect = 4e-36
Identities = 90/267 (33%), Positives = 141/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 377 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 436
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 437 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 494
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
G+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 495 TYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 554
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 555 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 614
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 615 NCTNELYMMMRDCWHAVPSQRPTFKQL 641
>X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein.
Length = 272
Score = 148 bits (359), Expect = 4e-35
Identities = 84/272 (30%), Positives = 140/272 (51%), Gaps = 15/272 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
+G FG V E+ +V VK + A+ + + L+E + H V ++G
Sbjct: 8 KGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVG 67
Query: 300 VSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMA 354
VS+ + P ++ P+ ++ FLLA R L Q ++R
Sbjct: 68 VSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR--------IGENPFNLPLQTLIRFM 118
Query: 355 LHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPI 414
+ G+ YL S++ +H+D+AARNC++ E++ V +AD LSR ++ DY+ G P+
Sbjct: 119 VDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPV 178
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
KWLALE+L ++ +DVWA GV +WE+ T PYA ++ E+ YL G RL+QP
Sbjct: 179 KWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQPPE 238
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFLRD 506
C ++++ +M CW+ P RP+ L++ L +
Sbjct: 239 CMEDVYDLMYQCWSADPKQRPSFTCLRMELEN 270
>M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth factor
receptor protein.
Length = 822
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein.
Length = 768
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein.
Length = 817
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein.
Length = 771
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein.
Length = 830
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein.
Length = 819
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein.
Length = 819
Score = 148 bits (359), Expect = 4e-35
Identities = 89/267 (33%), Positives = 140/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYR----GTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVL 295
EG FG+V G D+ V VK + + A++ +S L+ E M+ + H+ ++
Sbjct: 490 EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII 549
Query: 296 SVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR--GVTIXXXXXXXXXXXLTTQHVVRM 353
++LG +D P + A N++ +L A R G+ +T + +V
Sbjct: 550 NLLGACTQD--GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSC 607
Query: 354 ALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRP 413
+ YL SQ +H+D+AARN +V EN + IAD L+RD+ DY+ N P
Sbjct: 608 TYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLP 667
Query: 414 IKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPA 473
+KW+A EAL R ++ +DVW+ GVL+WE+ TL PY + E+ L++G+R+ +PA
Sbjct: 668 VKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 727
Query: 474 NCPDELFAVMAYCWAMSPDDRPTLPQL 500
NC +EL+ +M CW P RPT QL
Sbjct: 728 NCTNELYMMMRDCWHAVPSQRPTFKQL 754
>M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary
thyroid carcinoma-encoded protein mRNA, complete cds. ).
Length = 503
Score = 147 bits (356), Expect = 9e-35
Identities = 95/313 (30%), Positives = 153/313 (48%), Gaps = 23/313 (7%)
Query: 207 LPAVAAEERARDLQQRIAELTIQ-------RCRVRLRSVAMEGTFGRVYRGTYADEEARE 259
L A +E RDL++ A +TI+ R + L EG FG+V + T + R
Sbjct: 82 LKCKALQEENRDLRK--ASVTIEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRG 139
Query: 260 --QEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAG 317
V VK + E+AS ++ LL E +L ++H V+ + G +D P LL A
Sbjct: 140 GYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQD--GPLLLIVEYAK 197
Query: 318 WRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQ 367
+ +++ FL R G LT ++ A G+ YL
Sbjct: 198 YGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEM 257
Query: 368 HVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQF 427
++H+D+AARN +V E ++ I+D LSRD++ D + P+KW+A+E+L +
Sbjct: 258 KLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIY 317
Query: 428 SPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCW 487
+ +DVW+ GVLLWE+ TL PY + P + L+ G+R+++P NC +E++ +M CW
Sbjct: 318 TTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCW 377
Query: 488 AMSPDDRPTLPQL 500
PD RP +
Sbjct: 378 KQEPDKRPVFADI 390
>BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene protein.
Length = 1072
Score = 147 bits (355), Expect = 1e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 732 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 791
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 792 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 849
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 850 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 909
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 910 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 969
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 970 MERPDNCSEEMYCLMLQCWKQEPDKRPVFADI 1001
>X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein.
Length = 435
Score = 146 bits (354), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 95 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 154
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 155 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 212
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 213 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 272
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 273 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 332
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 333 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 364
>X15786-1|CAA33787.1| 899|Homo sapiens retII protein.
Length = 899
Score = 146 bits (354), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 517 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 576
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 577 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 634
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 635 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 694
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 695 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 754
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 755 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 786
>X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret
proto-oncogene mRNA for tyrosine kinase. ).
Length = 860
Score = 146 bits (354), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 478 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 537
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 538 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 595
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 596 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 655
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 656 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 715
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 716 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 747
>U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase
protein.
Length = 723
Score = 146 bits (354), Expect = 2e-34
Identities = 88/301 (29%), Positives = 154/301 (51%), Gaps = 17/301 (5%)
Query: 218 DLQQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTV-AEHASQVQV 276
+L++++ ++ I + L + +G FG V E+ +V VK + A+ + +
Sbjct: 318 ELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDI 377
Query: 277 SLLLQEGCMLYGLHHERVLSVLGVSIEDQTA-----PFLLYPWDAGWRNMKLFLLACRGV 331
L+E + H V ++GVS+ + P ++ P+ ++ FLLA R
Sbjct: 378 EEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPF-MKHGDLHAFLLASR-- 434
Query: 332 TIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIAD 391
L Q ++R + G+ YL S++ +H+D+AARNC++ E++ V +AD
Sbjct: 435 ------IGENPFNLPLQTLIRFMVDTC-GMEYLSSRNFIHRDLAARNCMLAEDMTVCVAD 487
Query: 392 NALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPY 451
LSR ++ DY+ G P+KWLALE+L ++ +DVWA GV +WE+ T PY
Sbjct: 488 FGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPY 547
Query: 452 AEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHTQL 511
A ++ E+ YL G L+QP C ++++ +M CW+ P RP+ L++ L + QL
Sbjct: 548 AGIENAEIYNYLIGG-NLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENILGQL 606
Query: 512 T 512
+
Sbjct: 607 S 607
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 146 bits (354), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 394 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 453
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 454 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 511
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 512 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 571
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 572 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 631
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 632 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 663
>M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA
encoding a tyrosine kinase, partial cds. ).
Length = 805
Score = 146 bits (353), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 465 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 524
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 525 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 582
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 583 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDPYVKRS 642
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 643 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 702
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 703 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 734
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 146 bits (353), Expect = 2e-34
Identities = 84/272 (30%), Positives = 136/272 (50%), Gaps = 14/272 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 256 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 315
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 316 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 373
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 374 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDPYVKRS 433
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+R
Sbjct: 434 QGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHR 493
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+++P NC +E++ +M CW PD RP +
Sbjct: 494 MERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 525
>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase
receptor protein.
Length = 1091
Score = 145 bits (351), Expect = 4e-34
Identities = 85/273 (31%), Positives = 137/273 (50%), Gaps = 15/273 (5%)
Query: 241 EGTFGRVYRGT--YADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FG+V + T + A V VK + E+AS ++ LL E +L ++H V+ +
Sbjct: 708 EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLY 767
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACR----------GVTIXXXXXXXXXXXLTTQ 348
G +D P LL A + +++ FL R G LT
Sbjct: 768 GACSQD--GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMG 825
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
++ A G+ YL ++H+D+AARN +V E ++ I+D LSRD++ D +
Sbjct: 826 DLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRS 885
Query: 409 NENR-PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
R P+KW+A+E+L ++ +DVW+ GVLLWE+ TL PY + P + L+ G+
Sbjct: 886 QVGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGH 945
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P NC +E++ +M CW PD RP +
Sbjct: 946 RMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 978
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 337
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 338 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 383
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 384 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 442
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 443 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 502
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 544
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 337
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 338 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 383
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 384 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 442
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 443 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 502
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 544
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 296 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 350
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 351 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 396
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 397 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 455
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 456 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 515
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 516 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 557
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 322
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 323 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 368
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 369 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 427
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 428 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 487
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 488 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 529
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 337
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 338 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 383
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 384 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 442
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 443 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 502
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 544
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 322
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 323 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 368
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 369 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 427
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 428 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 487
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 488 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 529
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 337
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 338 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 383
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 384 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 442
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 443 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 502
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 544
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 322
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 323 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 368
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 369 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 427
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 428 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 487
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 488 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 529
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 283 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 337
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 338 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 383
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 384 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 442
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 443 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 502
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 503 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 544
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 142 bits (343), Expect = 4e-33
Identities = 90/282 (31%), Positives = 138/282 (48%), Gaps = 21/282 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 268 MERTDITMKHKLGGGQYGEVYVGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 322
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C + T
Sbjct: 323 EIKHPNLVQLLGVCTLEP--PFYIVTEYMPYGNLLDYLRECNREEV------------TA 368
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 369 VVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSR-LMTGDTYTAH 427
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L FS +DVWA GVLLWE+ T PY +D +V L GY
Sbjct: 428 AGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGY 487
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL-QIFLRDFH 508
R++QP CP +++ +M CW SP DRP+ + Q F FH
Sbjct: 488 RMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH 529
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 142 bits (343), Expect = 4e-33
Identities = 85/290 (29%), Positives = 141/290 (48%), Gaps = 3/290 (1%)
Query: 213 EERARDLQQRIAELT-IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHA 271
EE A + RIA++ I+R + L+ EG FG+V+ + + ++LV A
Sbjct: 11 EEHAMPIG-RIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD 69
Query: 272 SQVQVSLLLQ-EGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG 330
+ Q E +L L HE ++ GV + + G N L
Sbjct: 70 PTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 129
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
+ + L ++ +A G++YL SQH +H+D+A RNC+V NL V I
Sbjct: 130 MILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIG 189
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D +SRD++ DY+ +G + PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP
Sbjct: 190 DFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQP 249
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ ++ EV + G L++P CP E++ VM CW P R + ++
Sbjct: 250 WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 299
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 142 bits (343), Expect = 4e-33
Identities = 85/290 (29%), Positives = 141/290 (48%), Gaps = 3/290 (1%)
Query: 213 EERARDLQQRIAELT-IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHA 271
EE A + RIA++ I+R + L+ EG FG+V+ + + ++LV A
Sbjct: 101 EEHAMPIG-RIADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKD 159
Query: 272 SQVQVSLLLQ-EGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG 330
+ Q E +L L HE ++ GV + + G N L
Sbjct: 160 PTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDA 219
Query: 331 VTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIA 390
+ + L ++ +A G++YL SQH +H+D+A RNC+V NL V I
Sbjct: 220 MILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIG 279
Query: 391 DNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQP 450
D +SRD++ DY+ +G + PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP
Sbjct: 280 DFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQP 339
Query: 451 YAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ ++ EV + G L++P CP E++ VM CW P R + ++
Sbjct: 340 WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 389
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 140 bits (340), Expect = 8e-33
Identities = 79/274 (28%), Positives = 132/274 (48%), Gaps = 1/274 (0%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQ-EGCML 286
I+R + L+ EG FG+V+ + + ++LV A + Q E +L
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELL 592
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLT 346
L HE ++ GV + + G N L + + L
Sbjct: 593 TNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPNAMILVDGQPRQAKGELG 652
Query: 347 TQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCL 406
++ +A G++YL SQH +H+D+A RNC+V NL V I D +SRD++ DY+ +
Sbjct: 653 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRV 712
Query: 407 GDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG 466
G + PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ EV + G
Sbjct: 713 GGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQG 772
Query: 467 YRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
L++P CP E++ VM CW P R + ++
Sbjct: 773 RVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 806
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 291
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 292 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 339
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 340 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 396
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 397 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 456
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 457 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 291
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 292 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 339
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 340 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 396
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 397 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 456
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 457 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 310
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 311 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 358
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 359 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 415
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 416 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 475
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 476 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 291
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 292 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 339
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 340 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 396
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 397 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYELLEKDY 456
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 457 RMKRPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 310
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 311 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 358
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 359 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 415
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 416 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 475
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 476 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein.
Length = 940
Score = 140 bits (338), Expect = 1e-32
Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 2/277 (0%)
Query: 233 VRLRSVAMEGTFGRVYRG-TYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHH 291
VR E FG++Y+G Y Q V +KT+ ++ + Q + QE ++ LHH
Sbjct: 476 VRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHH 535
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG-VTIXXXXXXXXXXXLTTQHV 350
++ +LG ++Q L + G + L + + V L
Sbjct: 536 PNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 595
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
+ +A+ G+ YL S +HKD+AARN ++ E L V I+D LSR+++ ADY+ +
Sbjct: 596 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 655
Query: 411 NRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
PI+W+ EA+ +FS +D+W+ GV+LWE+ + QPY EV +R L
Sbjct: 656 LLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP 715
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
+CP ++++M CW P RP + + LR +
Sbjct: 716 CSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 752
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 310
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 311 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 358
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 359 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 415
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 416 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 475
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 476 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 140 bits (338), Expect = 1e-32
Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 2/277 (0%)
Query: 233 VRLRSVAMEGTFGRVYRG-TYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHH 291
VR E FG++Y+G Y Q V +KT+ ++ + Q + QE ++ LHH
Sbjct: 473 VRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHH 532
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG-VTIXXXXXXXXXXXLTTQHV 350
++ +LG ++Q L + G + L + + V L
Sbjct: 533 PNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
+ +A+ G+ YL S +HKD+AARN ++ E L V I+D LSR+++ ADY+ +
Sbjct: 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652
Query: 411 NRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
PI+W+ EA+ +FS +D+W+ GV+LWE+ + QPY EV +R L
Sbjct: 653 LLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP 712
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
+CP ++++M CW P RP + + LR +
Sbjct: 713 CSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 749
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 310
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 311 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 358
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 359 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 415
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 416 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 475
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 476 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 140 bits (338), Expect = 1e-32
Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 2/277 (0%)
Query: 233 VRLRSVAMEGTFGRVYRG-TYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHH 291
VR E FG++Y+G Y Q V +KT+ ++ + Q + QE ++ LHH
Sbjct: 473 VRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHH 532
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG-VTIXXXXXXXXXXXLTTQHV 350
++ +LG ++Q L + G + L + + V L
Sbjct: 533 PNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
+ +A+ G+ YL S +HKD+AARN ++ E L V I+D LSR+++ ADY+ +
Sbjct: 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652
Query: 411 NRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
PI+W+ EA+ +FS +D+W+ GV+LWE+ + QPY EV +R L
Sbjct: 653 LLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP 712
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
+CP ++++M CW P RP + + LR +
Sbjct: 713 CSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 749
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 256 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 310
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 311 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 358
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 359 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 415
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 416 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 475
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 476 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 237 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 291
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 292 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 339
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 340 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 396
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 397 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 456
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 457 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 140 bits (338), Expect = 1e-32
Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 2/277 (0%)
Query: 233 VRLRSVAMEGTFGRVYRG-TYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHH 291
VR E FG++Y+G Y Q V +KT+ ++ + Q + QE ++ LHH
Sbjct: 473 VRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHH 532
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG-VTIXXXXXXXXXXXLTTQHV 350
++ +LG ++Q L + G + L + + V L
Sbjct: 533 PNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
+ +A+ G+ YL S +HKD+AARN ++ E L V I+D LSR+++ ADY+ +
Sbjct: 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652
Query: 411 NRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
PI+W+ EA+ +FS +D+W+ GV+LWE+ + QPY EV +R L
Sbjct: 653 LLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP 712
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
+CP ++++M CW P RP + + LR +
Sbjct: 713 CSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 749
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 140 bits (338), Expect = 1e-32
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 20/273 (7%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
++R + ++ G +G VY G + + V VKT+ E +V+ L+E ++
Sbjct: 274 MERTDITMKHKLGGGQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMK 328
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
+ H ++ +LGV + PF + + N+ +L C +
Sbjct: 329 EIKHPNLVQLLGVCTREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV---------- 376
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ MA + YL ++ +H+D+AARNC+V EN V +AD LSR L D +
Sbjct: 377 --LLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAH 433
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW A E+L +FS +DVWA GVLLWE+ T PY +D +V L Y
Sbjct: 434 AGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDY 493
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
R+++P CP++++ +M CW +P DRP+ ++
Sbjct: 494 RMERPEGCPEKVYELMRACWQWNPSDRPSFAEI 526
>M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor
protein.
Length = 937
Score = 139 bits (336), Expect = 2e-32
Identities = 80/277 (28%), Positives = 132/277 (47%), Gaps = 2/277 (0%)
Query: 233 VRLRSVAMEGTFGRVYRG-TYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHH 291
VR E FG++Y+G Y Q V +KT+ ++ + Q QE ++ LHH
Sbjct: 473 VRFMEELGECAFGKIYKGHLYLPGMDHAQLVAIKTLKDYNNPQQWMEFQQEASLMAELHH 532
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRG-VTIXXXXXXXXXXXLTTQHV 350
++ +LG ++Q L + G + L + + V L
Sbjct: 533 PNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTVKSSLDHGDF 592
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
+ +A+ G+ YL S +HKD+AARN ++ E L V I+D LSR+++ ADY+ +
Sbjct: 593 LHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKS 652
Query: 411 NRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQ 470
PI+W+ EA+ +FS +D+W+ GV+LWE+ + QPY EV +R L
Sbjct: 653 LLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLP 712
Query: 471 QPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
+CP ++++M CW P RP + + LR +
Sbjct: 713 CSEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLRSW 749
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 139 bits (336), Expect = 2e-32
Identities = 82/262 (31%), Positives = 135/262 (51%), Gaps = 8/262 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQE--VLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
+G+FG VY G EA E+ V +KTV E AS + L+E ++ V+ +L
Sbjct: 958 QGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLL 1017
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
GV + Q ++ G ++K L + R +++MA
Sbjct: 1018 GVVSQGQPTLVIMELMTRG--DLKSHLRSLRP----EAENNPGLPQPALGEMIQMAGEIA 1071
Query: 359 DGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLA 418
DG+ YL + +H+D+AARNC+V ++ V I D ++RD++ DY+ G P++W+A
Sbjct: 1072 DGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMA 1131
Query: 419 LEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDE 478
E+L F+ +DVW+ GV+LWE+ TLA QPY + +V ++ DG L++ CP +
Sbjct: 1132 PESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQ 1191
Query: 479 LFAVMAYCWAMSPDDRPTLPQL 500
L +M+ CW +P RP+ +
Sbjct: 1192 LQELMSRCWQPNPRLRPSFTHI 1213
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 139 bits (336), Expect = 2e-32
Identities = 82/262 (31%), Positives = 135/262 (51%), Gaps = 8/262 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQE--VLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
+G+FG VY G EA E+ V +KTV E AS + L+E ++ V+ +L
Sbjct: 987 QGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLL 1046
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
GV + Q ++ G ++K L + R +++MA
Sbjct: 1047 GVVSQGQPTLVIMELMTRG--DLKSHLRSLRP----EAENNPGLPQPALGEMIQMAGEIA 1100
Query: 359 DGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLA 418
DG+ YL + +H+D+AARNC+V ++ V I D ++RD++ DY+ G P++W+A
Sbjct: 1101 DGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMA 1160
Query: 419 LEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDE 478
E+L F+ +DVW+ GV+LWE+ TLA QPY + +V ++ DG L++ CP +
Sbjct: 1161 PESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQ 1220
Query: 479 LFAVMAYCWAMSPDDRPTLPQL 500
L +M+ CW +P RP+ +
Sbjct: 1221 LQELMSRCWQPNPRLRPSFTHI 1242
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 139 bits (336), Expect = 2e-32
Identities = 81/259 (31%), Positives = 129/259 (49%), Gaps = 20/259 (7%)
Query: 242 GTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
G +G VY G + + V VKT+ E +V+ L+E ++ + H ++ +LGV
Sbjct: 70 GQYGEVYEGVW---KKYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLLGVC 124
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
+ PF + + N+ +L C + ++ MA +
Sbjct: 125 TREP--PFYIITEFMTYGNLLDYLRECNRQEVNAVV------------LLYMATQISSAM 170
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
YL ++ +H+D+AARNC+V EN V +AD LSR L D + PIKW A E+
Sbjct: 171 EYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSR-LMTGDTYTAHAGAKFPIKWTAPES 229
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFA 481
L +FS +DVWA GVLLWE+ T PY +D +V L YR+++P CP++++
Sbjct: 230 LAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYE 289
Query: 482 VMAYCWAMSPDDRPTLPQL 500
+M CW +P DRP+ ++
Sbjct: 290 LMRACWQWNPSDRPSFAEI 308
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 137 bits (332), Expect = 8e-32
Identities = 88/272 (32%), Positives = 134/272 (49%), Gaps = 20/272 (7%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
+G FG VY+GT D+ + V VKT E Q LQE +L H ++ ++GV
Sbjct: 571 KGNFGEVYKGTLKDKTS----VAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGV 626
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ Q ++ G FL R L + +V+ +L A G
Sbjct: 627 CTQRQPVYIIMELVSGGD-----FLTFLR----------RKKDELKLKQLVKFSLDAAAG 671
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+LYL S++ +H+D+AARNC+V EN + I+D +SR Y G + PIKW A E
Sbjct: 672 MLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQI-PIKWTAPE 730
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
AL ++S +DVW+ G+LLWE +L PY + + + GYR+ P +CP+++
Sbjct: 731 ALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDIS 790
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRDFHTQLT 512
+M CW P++RP +LQ L +LT
Sbjct: 791 KIMMKCWDYKPENRPKFSELQKELTIIKRKLT 822
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 487 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 546
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 547 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 604
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 605 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 664
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 665 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 724
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 725 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 760
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 497 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 556
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 557 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 614
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 615 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 674
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 675 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 734
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 735 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 770
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 581 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 640
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 641 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 698
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 699 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 758
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 759 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 818
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 819 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 854
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 589 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 648
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 649 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 706
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 707 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 766
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 767 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 826
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 827 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 862
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 581 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 640
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 641 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 698
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 699 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 758
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 759 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 818
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 819 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 854
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 589 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 648
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 649 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 706
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 707 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 766
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 767 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 826
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 827 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 862
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 136 bits (330), Expect = 1e-31
Identities = 85/276 (30%), Positives = 138/276 (50%), Gaps = 14/276 (5%)
Query: 241 EGTFGRVYRGTYADEEAREQ--EVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVL 298
EG FGRV++ E V VK + E AS + +E ++ + ++ +L
Sbjct: 583 EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLL 642
Query: 299 GVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXX----------LTTQ 348
GV + LL+ + A + ++ FL + T+ L+
Sbjct: 643 GVCAVGKPM-CLLFEYMA-YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 700
Query: 349 HVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGD 408
+ +A G+ YL + +H+D+A RNC+V EN+ V IAD LSR+++ ADY+ +
Sbjct: 701 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANE 760
Query: 409 NENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYR 468
N+ PI+W+ E++ +++ +DVWA GV+LWE+ + QPY + EV Y+RDG
Sbjct: 761 NDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNI 820
Query: 469 LQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
L P NCP EL+ +M CW+ P DRP+ + L
Sbjct: 821 LSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 856
>M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor
protein.
Length = 943
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 462 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 519
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 639
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 640 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
>BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 462 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 519
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 639
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 640 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
>AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 462 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 519
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 639
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 640 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
>AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 704
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 322 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 379
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 380 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 439
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 440 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 499
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 500 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 559
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 560 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 607
>AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 704
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 322 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 379
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 380 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 439
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 440 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 499
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 500 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 559
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 560 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 607
>AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 462 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 519
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 639
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 640 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
>AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 704
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 322 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 379
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 380 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 439
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 440 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 499
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 500 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 559
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 560 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 607
>AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine
kinase-like orphan receptor 2 protein.
Length = 943
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 462 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 519
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 520 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 579
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 580 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 639
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 640 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 699
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 700 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 747
>AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein.
Length = 910
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 429 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 486
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 487 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 546
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 547 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 606
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 607 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 666
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 667 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 714
>AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase
transmembrane receptor ROR2 precursor variant protein.
Length = 919
Score = 136 bits (328), Expect = 2e-31
Identities = 86/288 (29%), Positives = 133/288 (46%), Gaps = 4/288 (1%)
Query: 220 QQRIAELTIQRCRVRLRSVAMEGTFGRVYRGTYADEEARE--QEVLVKTVAEHASQVQVS 277
Q ++ E+++ VR E FG+VY+G E Q V +KT+ + A
Sbjct: 438 QAKLKEISLSA--VRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPLRE 495
Query: 278 LLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXX 337
E + L H V+ +LGV +DQ + G + L + +
Sbjct: 496 EFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDD 555
Query: 338 XXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRD 397
L V + G+ YL S HV+HKD+A RN +V + L V I+D L R+
Sbjct: 556 DRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFRE 615
Query: 398 LFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPF 457
++ ADY+ L N PI+W+A EA+ +FS +D+W+ GV+LWE+ + QPY
Sbjct: 616 VYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQ 675
Query: 458 EVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
+V +R+ L P +CP ++A+M CW P RP + LR
Sbjct: 676 DVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLR 723
>U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinase
receptor protein.
Length = 1620
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 1125 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 1184
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 1185 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 1234
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 1235 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 1294
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 1295 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 1354
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 1355 PGPVYRIMTQCWQHQPEDRP 1374
>U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinase
protein.
Length = 1620
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 1125 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 1184
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 1185 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 1234
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 1235 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 1294
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 1295 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 1354
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 1355 PGPVYRIMTQCWQHQPEDRP 1374
>U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic
lymphoma kinase fusion protein protein.
Length = 680
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 185 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 244
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 245 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 294
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 295 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 354
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 355 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 414
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 415 PGPVYRIMTQCWQHQPEDRP 434
>D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein.
Length = 680
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 185 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 244
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 245 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 294
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 295 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 354
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 355 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 414
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 415 PGPVYRIMTQCWQHQPEDRP 434
>AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplastic
large cell lymphoma kinase extra long form protein.
Length = 803
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 308 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 367
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 368 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 417
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 418 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 477
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 478 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 537
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 538 PGPVYRIMTQCWQHQPEDRP 557
>AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplastic
lymphoma kinase (Ki-1) fusion protein long form protein.
Length = 756
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 261 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 320
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 321 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 370
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 371 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 430
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 431 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 490
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 491 PGPVYRIMTQCWQHQPEDRP 510
>AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplastic
lymphoma kinase fusion protein protein.
Length = 701
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 206 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 265
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 266 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 315
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 316 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 375
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 376 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 435
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 436 PGPVYRIMTQCWQHQPEDRP 455
>AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein.
Length = 1192
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 697 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 756
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 757 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 806
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 807 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 866
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 867 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 926
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 927 PGPVYRIMTQCWQHQPEDRP 946
>AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kinase
Ki-1 variant protein.
Length = 1626
Score = 134 bits (325), Expect = 5e-31
Identities = 83/260 (31%), Positives = 124/260 (47%), Gaps = 16/260 (6%)
Query: 242 GTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLG 299
G FG VY G + + +V VKT+ E S+ L E ++ +H+ ++ +G
Sbjct: 1131 GAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIG 1190
Query: 300 VSIEDQTAP-FLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHAL 358
VS+ Q+ P F+L AG ++K FL R L HV R
Sbjct: 1191 VSL--QSLPRFILLELMAGG-DLKSFLRETRP----RPSQPSSLAMLDLLHVAR---DIA 1240
Query: 359 DGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPADYHCLGDNENRPIK 415
G YL H +H+DIAARNC++ I D ++RD++ A Y+ G P+K
Sbjct: 1241 CGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK 1300
Query: 416 WLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANC 475
W+ EA + F+ D W+ GVLLWE+ +L + PY EV ++ G R+ P NC
Sbjct: 1301 WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNC 1360
Query: 476 PDELFAVMAYCWAMSPDDRP 495
P ++ +M CW P+DRP
Sbjct: 1361 PGPVYRIMTQCWQHQPEDRP 1380
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 134 bits (324), Expect = 7e-31
Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLG 299
EG FG+V R ++ + +K + E+AS+ E +L L HH ++++LG
Sbjct: 847 EGNFGQVIRAMIK-KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQHVVRMALHA 357
+ +++ ++ + A + N+ FL R + L+++ ++R A A
Sbjct: 906 -ACKNRGYLYIAIEY-APYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 963
Query: 358 LDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWL 417
+G+ YL + +H+D+AARN +V ENL IAD LSR + + P++W+
Sbjct: 964 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWM 1020
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYR++QP NC D
Sbjct: 1021 AIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDD 1080
Query: 478 ELFAVMAYCWAMSPDDRPTLPQLQIFL 504
E++ +M CW P +RP Q+ + L
Sbjct: 1081 EVYELMRQCWRDRPYERPPFAQIALQL 1107
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 134 bits (324), Expect = 7e-31
Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLG 299
EG FG+V R ++ + +K + E+AS+ E +L L HH ++++LG
Sbjct: 847 EGNFGQVIRAMIK-KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQHVVRMALHA 357
+ +++ ++ + A + N+ FL R + L+++ ++R A A
Sbjct: 906 -ACKNRGYLYIAIEY-APYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 963
Query: 358 LDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWL 417
+G+ YL + +H+D+AARN +V ENL IAD LSR + + P++W+
Sbjct: 964 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWM 1020
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYR++QP NC D
Sbjct: 1021 AIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDD 1080
Query: 478 ELFAVMAYCWAMSPDDRPTLPQLQIFL 504
E++ +M CW P +RP Q+ + L
Sbjct: 1081 EVYELMRQCWRDRPYERPPFAQIALQL 1107
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 134 bits (324), Expect = 7e-31
Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLG 299
EG FG+V R ++ + +K + E+AS+ E +L L HH ++++LG
Sbjct: 847 EGNFGQVIRAMIK-KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 905
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQHVVRMALHA 357
+ +++ ++ + A + N+ FL R + L+++ ++R A A
Sbjct: 906 -ACKNRGYLYIAIEY-APYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 963
Query: 358 LDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWL 417
+G+ YL + +H+D+AARN +V ENL IAD LSR + + P++W+
Sbjct: 964 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWM 1020
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYR++QP NC D
Sbjct: 1021 AIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDD 1080
Query: 478 ELFAVMAYCWAMSPDDRPTLPQLQIFL 504
E++ +M CW P +RP Q+ + L
Sbjct: 1081 EVYELMRQCWRDRPYERPPFAQIALQL 1107
>AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 541
Score = 134 bits (324), Expect = 7e-31
Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLG 299
EG FG+V R ++ + +K + E+AS+ E +L L HH ++++LG
Sbjct: 250 EGNFGQVIRAMIK-KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 308
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQHVVRMALHA 357
+ +++ ++ + A + N+ FL R + L+++ ++R A A
Sbjct: 309 -ACKNRGYLYIAIEY-APYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 366
Query: 358 LDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWL 417
+G+ YL + +H+D+AARN +V ENL IAD LSR + + P++W+
Sbjct: 367 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWM 423
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYR++QP NC D
Sbjct: 424 AIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDD 483
Query: 478 ELFAVMAYCWAMSPDDRPTLPQLQIFL 504
E++ +M CW P +RP Q+ + L
Sbjct: 484 EVYELMRQCWRDRPYERPPFAQIALQL 510
>AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein.
Length = 421
Score = 134 bits (324), Expect = 7e-31
Identities = 81/267 (30%), Positives = 139/267 (52%), Gaps = 9/267 (3%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HHERVLSVLG 299
EG FG+V R ++ + +K + E+AS+ E +L L HH ++++LG
Sbjct: 130 EGNFGQVIRAMIK-KDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLG 188
Query: 300 VSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQHVVRMALHA 357
+ +++ ++ + A + N+ FL R + L+++ ++R A A
Sbjct: 189 -ACKNRGYLYIAIEY-APYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDA 246
Query: 358 LDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWL 417
+G+ YL + +H+D+AARN +V ENL IAD LSR + + P++W+
Sbjct: 247 ANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWM 303
Query: 418 ALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPD 477
A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYR++QP NC D
Sbjct: 304 AIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDD 363
Query: 478 ELFAVMAYCWAMSPDDRPTLPQLQIFL 504
E++ +M CW P +RP Q+ + L
Sbjct: 364 EVYELMRQCWRDRPYERPPFAQIALQL 390
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 300 IKRRDIVLKWELGEGAFGKVFLAESHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 359
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 360 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 417
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 418 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 477
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 478 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 537
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 538 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 577
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 212 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 271
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 272 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 329
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 330 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 389
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 390 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 449
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 450 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 489
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 499 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 558
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 559 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 616
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 617 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 676
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 677 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 736
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 737 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 776
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 504 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 563
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 564 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 621
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 622 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 681
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 682 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 741
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 742 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 781
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 499 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 558
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 559 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 616
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 617 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 676
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 677 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 736
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 737 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 776
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 134 bits (323), Expect = 9e-31
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 505 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 564
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 565 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 622
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 623 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 682
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 683 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 742
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 743 GRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 782
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 132 bits (320), Expect = 2e-30
Identities = 78/280 (27%), Positives = 138/280 (49%), Gaps = 4/280 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 148 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 207
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 208 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 265
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 266 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 325
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 326 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 385
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLR 505
G L++P CP E++A+M CW P R ++ + L+
Sbjct: 386 GRELERPRACPPEVYAIMRGCWHGEPQQRHSIKDVHARLQ 425
>BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 132 bits (320), Expect = 2e-30
Identities = 83/275 (30%), Positives = 138/275 (50%), Gaps = 9/275 (3%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HH 291
++ + V EG FG+V + + R + +K + E+AS+ E +L L HH
Sbjct: 824 IKFQDVIGEGNFGQVLKARIKKDGLR-MDAAIKRMKEYASKDDHRDFAGELEVLCKLGHH 882
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQH 349
++++LG + E + +L + A N+ FL R + L++ H
Sbjct: 883 PNIINLLG-ACEHRGYLYLAIEY-APHGNLLDFLRKSRVLETDPAFAIANSTASTLSSHH 940
Query: 350 VVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDN 409
++ A G+ YL + +H+D+AARN +V EN IAD LSR +G
Sbjct: 941 LLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMG-- 998
Query: 410 ENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRL 469
P++W+A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYRL
Sbjct: 999 -RLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRL 1057
Query: 470 QQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
++P NC DE++ +M CW P +RP+ Q+ + L
Sbjct: 1058 EKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1092
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 131 bits (317), Expect = 5e-30
Identities = 76/268 (28%), Positives = 133/268 (49%), Gaps = 4/268 (1%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVA-EHASQVQVSLLLQEGCML 286
I+R + L+ EG FG+V+ + + ++LV A + AS+ +E +L
Sbjct: 328 IKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELL 387
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACR-GVTIXXXXXXXXXXXL 345
L H+ ++ GV E + P L+ ++ FL + + L
Sbjct: 388 TMLQHQHIVRFFGVCTEGR--PLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 445
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHC 405
++ +A G++YL H +H+D+A RNC+V + L V I D +SRD++ DY+
Sbjct: 446 GLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYR 505
Query: 406 LGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRD 465
+G PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+ ++ E +
Sbjct: 506 VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQ 565
Query: 466 GYRLQQPANCPDELFAVMAYCWAMSPDD 493
G L++P CP E++A+M CW P +
Sbjct: 566 GRELERPRACPPEVYAIMRGCWQREPSN 593
>L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 1124
Score = 131 bits (317), Expect = 5e-30
Identities = 83/275 (30%), Positives = 138/275 (50%), Gaps = 9/275 (3%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HH 291
++ + V EG FG+V + + R + +K + E+AS+ E +L L HH
Sbjct: 824 IKFQDVIGEGNFGQVLKARIKKDGLR-MDAAIKRMKEYASKDDHRDFAGELEVLCKLGHH 882
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQH 349
++++LG + E + +L + A N+ FL R + L++Q
Sbjct: 883 PNIINLLG-ACEHRGYLYLAIEY-APHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQ 940
Query: 350 VVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDN 409
++ A G+ YL + +H+D+AARN +V EN IAD LSR +G
Sbjct: 941 LLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMG-- 998
Query: 410 ENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRL 469
P++W+A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYRL
Sbjct: 999 -RLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRL 1057
Query: 470 QQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
++P NC DE++ +M CW P +RP+ Q+ + L
Sbjct: 1058 EKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1092
>AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 131 bits (317), Expect = 5e-30
Identities = 83/275 (30%), Positives = 138/275 (50%), Gaps = 9/275 (3%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HH 291
++ + V EG FG+V + + R + +K + E+AS+ E +L L HH
Sbjct: 824 IKFQDVIGEGNFGQVLKARIKKDGLR-MDAAIKRMKEYASKDDHRDFAGELEVLCKLGHH 882
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQH 349
++++LG + E + +L + A N+ FL R + L++Q
Sbjct: 883 PNIINLLG-ACEHRGYLYLAIEY-APHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQ 940
Query: 350 VVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDN 409
++ A G+ YL + +H+D+AARN +V EN IAD LSR +G
Sbjct: 941 LLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMG-- 998
Query: 410 ENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRL 469
P++W+A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYRL
Sbjct: 999 -RLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRL 1057
Query: 470 QQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
++P NC DE++ +M CW P +RP+ Q+ + L
Sbjct: 1058 EKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1092
>AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase variant
protein.
Length = 1157
Score = 131 bits (317), Expect = 5e-30
Identities = 83/275 (30%), Positives = 138/275 (50%), Gaps = 9/275 (3%)
Query: 233 VRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGL-HH 291
++ + V EG FG+V + + R + +K + E+AS+ E +L L HH
Sbjct: 857 IKFQDVIGEGNFGQVLKARIKKDGLR-MDAAIKRMKEYASKDDHRDFAGELEVLCKLGHH 915
Query: 292 ERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTI--XXXXXXXXXXXLTTQH 349
++++LG + E + +L + A N+ FL R + L++Q
Sbjct: 916 PNIINLLG-ACEHRGYLYLAIEY-APHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQ 973
Query: 350 VVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDN 409
++ A G+ YL + +H+D+AARN +V EN IAD LSR +G
Sbjct: 974 LLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMG-- 1031
Query: 410 ENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRL 469
P++W+A+E+L ++ +DVW+ GVLLWE+ +L PY + E+ L GYRL
Sbjct: 1032 -RLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRL 1090
Query: 470 QQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
++P NC DE++ +M CW P +RP+ Q+ + L
Sbjct: 1091 EKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSL 1125
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase
protein.
Length = 1052
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 477 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 520
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 581 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 639
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 640 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 673
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 417 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 476
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 477 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 520
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 580
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 581 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 639
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 640 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 673
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 45 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 104
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 105 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 148
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 149 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 208
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 209 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 267
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 268 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 301
>AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens
cDNA FLJ37680 fis, clone BRHIP2012923, highly similar to
FOCAL ADHESION KINASE 1 (EC 2.7.1.112). ).
Length = 720
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 85 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 144
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 145 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 188
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 189 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 248
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 249 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 307
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 308 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 341
>AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 1007
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 369 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 428
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 429 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 472
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 473 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 532
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 533 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 591
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 592 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 625
>AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 975
Score = 130 bits (313), Expect = 2e-29
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE +
Sbjct: 337 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMR 396
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
H ++ ++GV E+ W M+L L L
Sbjct: 397 QFDHPHIVKLIGVITENPV-----------WIIMELCTLG-----ELRSFLQVRKYSLDL 440
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
++ A L YL S+ +H+DIAARN +V N V + D LSR + + Y+
Sbjct: 441 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKAS 500
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V +V + +G
Sbjct: 501 KGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGE 559
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
RL P NCP L+++M CWA P RP +L+
Sbjct: 560 RLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 593
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 865
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 866 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 918
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 919 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 977
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASALGD 1063
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 865
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 866 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 918
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 919 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 977
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASALGD 1063
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 865
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 866 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 918
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 919 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 977
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASALGD 1063
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 751 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 809
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 810 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 862
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 863 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 921
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 922 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 981
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 982 RLMQRCWALSPKDRPSFSEIASALGD 1007
>AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor
precursor PTK7-3 protein.
Length = 940
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 677 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 735
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 736 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 788
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 789 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 847
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 848 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 907
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 908 RLMQRCWALSPKDRPSFSEIASALGD 933
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 767 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 825
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 826 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 878
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 879 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 937
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 938 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 997
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 998 RLMQRCWALSPKDRPSFSEIASALGD 1023
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 865
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 866 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 918
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 919 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 977
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASALGD 1063
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 128 bits (309), Expect = 5e-29
Identities = 84/266 (31%), Positives = 136/266 (51%), Gaps = 12/266 (4%)
Query: 244 FGRVY--RGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVS 301
FG V+ + +E E VLVK++ Q Q+ +E M L+H V+ +LG+
Sbjct: 807 FGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLC 865
Query: 302 IEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGL 361
E + +L D G ++K FL + L+T+ V + G+
Sbjct: 866 REAEPHYMVLEYVDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGM 918
Query: 362 LYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEA 421
+L + +HKD+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA
Sbjct: 919 EHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEA 977
Query: 422 LTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELF 480
+ + FS +DVWA GVL+WE+ T P+ EV A L+ G RL QP CP +L+
Sbjct: 978 ILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLY 1037
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRD 506
+M CWA+SP DRP+ ++ L D
Sbjct: 1038 RLMQRCWALSPKDRPSFSEIASALGD 1063
>X52213-1|CAA36460.1| 464|Homo sapiens ltk protein.
Length = 464
Score = 127 bits (307), Expect = 8e-29
Identities = 80/277 (28%), Positives = 126/277 (45%), Gaps = 13/277 (4%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCM 285
+ V L G FG VY G ++ +V +KT+ E S L E +
Sbjct: 106 VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALI 165
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
+ H+ ++ +G+S+ LL G +MK FL R L
Sbjct: 166 ISKFRHQNIVRCVGLSLRATPRLILLELMSGG--DMKSFLRHSRP-------HLGQPSPL 216
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDEN-LRVM-IADNALSRDLFPADY 403
+ ++++A G YL H +H+DIAARNC++ RV I D ++RD++ A Y
Sbjct: 217 VMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLMRGPSRVAKIGDFGMARDIYRASY 276
Query: 404 HCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYL 463
+ GD P+KW+ EA + F+ D W+ GVLLWE+ +L + PY EV ++
Sbjct: 277 YRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFV 336
Query: 464 RDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
G R+ P CP ++ +M CW P+ RP+ +
Sbjct: 337 VGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASI 373
>U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta
protein.
Length = 1009
Score = 127 bits (306), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGLFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein
protein.
Length = 364
Score = 127 bits (306), Expect = 1e-28
Identities = 81/254 (31%), Positives = 131/254 (51%), Gaps = 10/254 (3%)
Query: 254 DEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGVSIEDQTAPFLLYP 313
+E E VLVK++ Q Q+ +E M L+H V+ +LG+ E + +L
Sbjct: 113 EEGVAETLVLVKSLQSKDEQQQLDFR-RELEMFGKLNHANVVRLLGLCREAEPHYMVLEY 171
Query: 314 WDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKD 373
D G ++K FL + L+T+ V + G+ +L + +HKD
Sbjct: 172 VDLG--DLKQFLRISKS-----KDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKD 224
Query: 374 IAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADV 433
+AARNC+V +V ++ LS+D++ ++Y+ P++W++ EA+ + FS +DV
Sbjct: 225 LAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWV-PLRWMSPEAILEGDFSTKSDV 283
Query: 434 WALGVLLWELTTLAHQPYAEVDPFEVAAYLRDG-YRLQQPANCPDELFAVMAYCWAMSPD 492
WA GVL+WE+ T P+ EV A L+ G RL QP CP +L+ +M CWA+SP
Sbjct: 284 WAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPK 343
Query: 493 DRPTLPQLQIFLRD 506
DRP+ ++ L D
Sbjct: 344 DRPSFSEIASALGD 357
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 127 bits (306), Expect = 1e-28
Identities = 84/268 (31%), Positives = 129/268 (48%), Gaps = 21/268 (7%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
EG FG V+ G + V +K + ++ ++++ L +E L GL HER++ + V
Sbjct: 238 EGYFGEVWEGLWLGS----LPVAIKVIK--SANMKLTDLAKEIQTLKGLRHERLIRLHAV 291
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ + G N++ FL G L ++ A +G
Sbjct: 292 CSGGEPVYIVTELMRKG--NLQAFLGTPEG------------RALRLPPLLGFACQVAEG 337
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+ YL Q V+H+D+AARN +VD+ L +AD L+R L D + + P+KW A E
Sbjct: 338 MSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLAR-LLKDDIYSPSSSSKIPVKWTAPE 396
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
A R FS +DVW+ GVLL E+ T PY + E + GYRL +PA CP E++
Sbjct: 397 AANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVY 456
Query: 481 AVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
+M CW SP++RP+ L+ L H
Sbjct: 457 VLMLECWRSSPEERPSFATLREKLHAIH 484
>X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein.
Length = 803
Score = 126 bits (305), Expect = 1e-28
Identities = 78/278 (28%), Positives = 125/278 (44%), Gaps = 14/278 (5%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCM 285
+ V L G FG VY G ++ +V +KT+ E S L E +
Sbjct: 444 VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALI 503
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
+ H+ ++ +G+S+ LL G +MK FL R L
Sbjct: 504 ISKFRHQNIVRCVGLSLRATPRLILLELMSGG--DMKSFLRHSRP-------HLGQPSPL 554
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPAD 402
+ ++++A G YL H +H+DIAARNC++ + I D ++RD++ A
Sbjct: 555 VMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRAS 614
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ GD P+KW+ EA + F+ D W+ GVLLWE+ +L + PY EV +
Sbjct: 615 YYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDF 674
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ G R+ P CP ++ +M CW P+ RP+ +
Sbjct: 675 VVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASI 712
>U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein.
Length = 1009
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal
tyrosine kinase protein.
Length = 1009
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>S76475-1|AAB33111.1| 839|Homo sapiens trkC protein.
Length = 839
Score = 126 bits (305), Expect = 1e-28
Identities = 80/288 (27%), Positives = 133/288 (46%), Gaps = 15/288 (5%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQ-EGCML 286
I+R + L+ EG FG+V+ + + ++LV A + Q E +L
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELL 592
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLT 346
L HE ++ GV + + G N L + + L
Sbjct: 593 TNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELG 652
Query: 347 TQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYH-- 404
++ +A G++YL SQH +H+D+A RNC+V NL V I D +SRD++ DY+
Sbjct: 653 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRL 712
Query: 405 --------CL----GDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYA 452
C+ G + PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+
Sbjct: 713 FNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWF 772
Query: 453 EVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
++ EV + G L++P CP E++ VM CW P R + ++
Sbjct: 773 QLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 820
>L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase
protein.
Length = 1009
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase
protein.
Length = 864
Score = 126 bits (305), Expect = 1e-28
Identities = 78/278 (28%), Positives = 125/278 (44%), Gaps = 14/278 (5%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYAD--EEAREQEVLVKTVAEHASQVQVSLLLQEGCM 285
+ V L G FG VY G ++ +V +KT+ E S L E +
Sbjct: 505 VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLMEALI 564
Query: 286 LYGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXL 345
+ H+ ++ +G+S+ LL G +MK FL R L
Sbjct: 565 ISKFRHQNIVRCVGLSLRATPRLILLELMSGG--DMKSFLRHSRP-------HLGQPSPL 615
Query: 346 TTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVD---ENLRVMIADNALSRDLFPAD 402
+ ++++A G YL H +H+DIAARNC++ + I D ++RD++ A
Sbjct: 616 VMRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRAS 675
Query: 403 YHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAY 462
Y+ GD P+KW+ EA + F+ D W+ GVLLWE+ +L + PY EV +
Sbjct: 676 YYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDF 735
Query: 463 LRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
+ G R+ P CP ++ +M CW P+ RP+ +
Sbjct: 736 VVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASI 773
>BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 420 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 479
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 480 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 526
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 527 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 582
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 583 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 642
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 643 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 683
>AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens
cDNA FLJ46514 fis, clone THYMU3032798, highly similar
to Focal adhesion kinase 2 (EC 2.7.1.112). ).
Length = 596
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 166 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 225
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 226 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 272
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 273 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 328
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 329 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 388
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 389 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 429
>AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein.
Length = 839
Score = 126 bits (305), Expect = 1e-28
Identities = 80/288 (27%), Positives = 133/288 (46%), Gaps = 15/288 (5%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQ-EGCML 286
I+R + L+ EG FG+V+ + + ++LV A + Q E +L
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELL 592
Query: 287 YGLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLT 346
L HE ++ GV + + G N L + + L
Sbjct: 593 TNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELG 652
Query: 347 TQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYH-- 404
++ +A G++YL SQH +H+D+A RNC+V NL V I D +SRD++ DY+
Sbjct: 653 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRL 712
Query: 405 --------CL----GDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYA 452
C+ G + PI+W+ E++ R+F+ +DVW+ GV+LWE+ T QP+
Sbjct: 713 FNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWF 772
Query: 453 EVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQL 500
++ EV + G L++P CP E++ VM CW P R + ++
Sbjct: 773 QLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEI 820
>AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine
kinase 2 beta isoform a variant protein.
Length = 802
Score = 126 bits (305), Expect = 1e-28
Identities = 81/281 (28%), Positives = 127/281 (45%), Gaps = 17/281 (6%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
I R V L + EG FG VY G Y + + + V VKT + + + E ++
Sbjct: 425 IAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFMSEAVIMK 484
Query: 288 GLHHERVLSVLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTT 347
L H ++ ++G+ E+ T W M+L+ G + L
Sbjct: 485 NLDHPHIVKLIGIIEEEPT-----------WIIMELYPYGELGHYLERNKNSLKVLTL-- 531
Query: 348 QHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLG 407
V +L + YL S + +H+DIA RN +V V + D LSR + DY+
Sbjct: 532 ---VLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYY-KA 587
Query: 408 DNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
PIKW++ E++ R+F+ A+DVW V +WE+ + QP+ ++ +V L G
Sbjct: 588 SVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGD 647
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFH 508
RL +P CP L+ +M CW P DRP +L L D +
Sbjct: 648 RLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSDVY 688
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 126 bits (304), Expect = 2e-28
Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 237 SVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLS 296
+V EG FG VYRGT + V +KT+ + + Q L+E ++ H +L
Sbjct: 343 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 402
Query: 297 VLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALH 356
+ GV + + + + G + FL L +V M
Sbjct: 403 LEGVVTKRKPIMIITEFMENG--ALDAFL-------------REREDQLVPGQLVAMLQG 447
Query: 357 ALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSR--DLFPADYHCLGDNENRPI 414
G+ YL + + +H+D+AARN +V++NL ++D L+R D F Y G PI
Sbjct: 448 IASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKI--PI 505
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
+W A EA+ R F+ A+DVW+ G+++WE+ + +PY E+ EV + DGYRL P +
Sbjct: 506 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVD 565
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
CP L+ +M CWA RP +LQ L
Sbjct: 566 CPAPLYELMKNCWAYDRARRPHFQKLQAHL 595
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 126 bits (304), Expect = 2e-28
Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 237 SVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLS 296
+V EG FG VYRGT + V +KT+ + + Q L+E ++ H +L
Sbjct: 628 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 297 VLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALH 356
+ GV + + + + G + FL L +V M
Sbjct: 688 LEGVVTKRKPIMIITEFMENG--ALDAFL-------------REREDQLVPGQLVAMLQG 732
Query: 357 ALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSR--DLFPADYHCLGDNENRPI 414
G+ YL + + +H+D+AARN +V++NL ++D L+R D F Y G PI
Sbjct: 733 IASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKI--PI 790
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
+W A EA+ R F+ A+DVW+ G+++WE+ + +PY E+ EV + DGYRL P +
Sbjct: 791 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVD 850
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
CP L+ +M CWA RP +LQ L
Sbjct: 851 CPAPLYELMKNCWAYDRARRPHFQKLQAHL 880
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 126 bits (304), Expect = 2e-28
Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 237 SVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLS 296
+V EG FG VYRGT + V +KT+ + + Q L+E ++ H +L
Sbjct: 628 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 297 VLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALH 356
+ GV + + + + G + FL L +V M
Sbjct: 688 LEGVVTKRKPIMIITEFMENG--ALDAFL-------------REREDQLVPGQLVAMLQG 732
Query: 357 ALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSR--DLFPADYHCLGDNENRPI 414
G+ YL + + +H+D+AARN +V++NL ++D L+R D F Y G PI
Sbjct: 733 IASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKI--PI 790
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
+W A EA+ R F+ A+DVW+ G+++WE+ + +PY E+ EV + DGYRL P +
Sbjct: 791 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVD 850
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
CP L+ +M CWA RP +LQ L
Sbjct: 851 CPAPLYELMKNCWAYDRARRPHFQKLQAHL 880
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 126 bits (304), Expect = 2e-28
Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 237 SVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLS 296
+V EG FG VYRGT + V +KT+ + + Q L+E ++ H +L
Sbjct: 628 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 687
Query: 297 VLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALH 356
+ GV + + + + G + FL L +V M
Sbjct: 688 LEGVVTKRKPIMIITEFMENG--ALDAFL-------------REREDQLVPGQLVAMLQG 732
Query: 357 ALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSR--DLFPADYHCLGDNENRPI 414
G+ YL + + +H+D+AARN +V++NL ++D L+R D F Y G PI
Sbjct: 733 IASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKI--PI 790
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
+W A EA+ R F+ A+DVW+ G+++WE+ + +PY E+ EV + DGYRL P +
Sbjct: 791 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVD 850
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
CP L+ +M CWA RP +LQ L
Sbjct: 851 CPAPLYELMKNCWAYDRARRPHFQKLQAHL 880
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 126 bits (303), Expect = 2e-28
Identities = 83/270 (30%), Positives = 129/270 (47%), Gaps = 19/270 (7%)
Query: 237 SVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLS 296
+V EG FG VYRGT + V +KT+ + + Q L+E ++ H +L
Sbjct: 636 TVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 695
Query: 297 VLGVSIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALH 356
+ GV + + P ++ + FL L +V M
Sbjct: 696 LEGVVTKRK--PIMIITEFMENAALDAFL-------------REREDQLVPGQLVAMLQG 740
Query: 357 ALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSR--DLFPADYHCLGDNENRPI 414
G+ YL + + +H+D+AARN +V++NL ++D L+R D F Y G PI
Sbjct: 741 IASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKI--PI 798
Query: 415 KWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPAN 474
+W A EA+ R F+ A+DVW+ G+++WE+ + +PY E+ EV + DGYRL P +
Sbjct: 799 RWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVD 858
Query: 475 CPDELFAVMAYCWAMSPDDRPTLPQLQIFL 504
CP L+ +M CWA RP +LQ L
Sbjct: 859 CPAPLYELMKNCWAYDRARRPHFQKLQAHL 888
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 124 bits (299), Expect = 8e-28
Identities = 60/165 (36%), Positives = 92/165 (55%), Gaps = 1/165 (0%)
Query: 345 LTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYH 404
LT ++ MA +G++++ ++ +H+D+ A N +V + L IAD L+R L + +
Sbjct: 339 LTINKLLDMAAQIAEGMVFIEERNYIHRDLRAANILVSDTLSCKIADFGLAR-LIEDNEY 397
Query: 405 CLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLR 464
+ PIKW A EA+ F+ +DVW+ G+LL E+ T PY + EV L
Sbjct: 398 TAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNLEVIQNLE 457
Query: 465 DGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDFHT 509
GYR+ +P NCP+EL+ +M CW P+DRPT L+ L DF T
Sbjct: 458 RGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFT 502
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 123 bits (296), Expect = 2e-27
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
V MA G+ YL S++ +H+D+AARN +V E+ +AD L+R +F D + ++
Sbjct: 332 VDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR-VFKVDNEDIYESR 390
Query: 411 NR---PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ P+KW A EA+ +FS +DVW+ G+LL+E+ T PY+ + +V L Y
Sbjct: 391 HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY 450
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
RL QP+NCP + + +M CW P +RPT L+ L D+
Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY 490
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 123 bits (296), Expect = 2e-27
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
V MA G+ YL S++ +H+D+AARN +V E+ +AD L+R +F D + ++
Sbjct: 332 VDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR-VFKVDNEDIYESR 390
Query: 411 NR---PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ P+KW A EA+ +FS +DVW+ G+LL+E+ T PY+ + +V L Y
Sbjct: 391 HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY 450
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
RL QP+NCP + + +M CW P +RPT L+ L D+
Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY 490
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 123 bits (296), Expect = 2e-27
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
V MA G+ YL S++ +H+D+AARN +V E+ +AD L+R +F D + ++
Sbjct: 332 VDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR-VFKVDNEDIYESR 390
Query: 411 NR---PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ P+KW A EA+ +FS +DVW+ G+LL+E+ T PY+ + +V L Y
Sbjct: 391 HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY 450
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
RL QP+NCP + + +M CW P +RPT L+ L D+
Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY 490
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 123 bits (296), Expect = 2e-27
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
V MA G+ YL S++ +H+D+AARN +V E+ +AD L+R +F D + ++
Sbjct: 332 VDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR-VFKVDNEDIYESR 390
Query: 411 NR---PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ P+KW A EA+ +FS +DVW+ G+LL+E+ T PY+ + +V L Y
Sbjct: 391 HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY 450
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
RL QP+NCP + + +M CW P +RPT L+ L D+
Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY 490
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 123 bits (296), Expect = 2e-27
Identities = 59/160 (36%), Positives = 92/160 (57%), Gaps = 4/160 (2%)
Query: 351 VRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNE 410
V MA G+ YL S++ +H+D+AARN +V E+ +AD L+R +F D + ++
Sbjct: 332 VDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLAR-VFKVDNEDIYESR 390
Query: 411 NR---PIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGY 467
+ P+KW A EA+ +FS +DVW+ G+LL+E+ T PY+ + +V L Y
Sbjct: 391 HEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNY 450
Query: 468 RLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQIFLRDF 507
RL QP+NCP + + +M CW P +RPT L+ L D+
Sbjct: 451 RLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDY 490
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 122 bits (295), Expect = 2e-27
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 1/192 (0%)
Query: 318 WRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAAR 377
W N+ LL ++ LT ++ MA +G+ ++ ++ +H+D+ A
Sbjct: 339 WGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAA 398
Query: 378 NCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALG 437
N +V + L IAD L+R L + + + PIKW A EA+ F+ +DVW+ G
Sbjct: 399 NILVSDTLSCKIADFGLAR-LIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 457
Query: 438 VLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTL 497
+LL E+ T PY + EV L GYR+ +P NCP+EL+ +M CW P+DRPT
Sbjct: 458 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 517
Query: 498 PQLQIFLRDFHT 509
L+ L DF T
Sbjct: 518 DYLRSVLEDFFT 529
>AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 526
Score = 122 bits (295), Expect = 2e-27
Identities = 64/192 (33%), Positives = 98/192 (51%), Gaps = 1/192 (0%)
Query: 318 WRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAAR 377
W N+ LL ++ LT ++ MA +G+ ++ ++ +H+D+ A
Sbjct: 326 WGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAA 385
Query: 378 NCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALG 437
N +V + L IAD L+R L + + + PIKW A EA+ F+ +DVW+ G
Sbjct: 386 NILVSDTLSCKIADFGLAR-LIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFG 444
Query: 438 VLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTL 497
+LL E+ T PY + EV L GYR+ +P NCP+EL+ +M CW P+DRPT
Sbjct: 445 ILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTF 504
Query: 498 PQLQIFLRDFHT 509
L+ L DF T
Sbjct: 505 DYLRSVLEDFFT 516
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 122 bits (294), Expect = 3e-27
Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 28/260 (10%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
EG FG V +G Y Q+V VK + V L E ++ + HE ++ +LGV
Sbjct: 243 EGEFGAVLQGEYLG-----QKVAVKNIK---CDVTAQAFLDETAVMTKMQHENLVRLLGV 294
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ Q ++ G N+ FL RG + + T +++ +LH +G
Sbjct: 295 ILH-QGLYIVMEHVSKG--NLVNFLRT-RGRAL-----------VNTAQLLQFSLHVAEG 339
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+ YL S+ ++H+D+AARN +V E+L ++D L++ A+ L D+ P+KW A E
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAK----AERKGL-DSSRLPVKWTAPE 394
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
AL +F+ +DVW+ GVLLWE+ + PY ++ EV+ + GYR++ P CP +
Sbjct: 395 ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVH 454
Query: 481 AVMAYCWAMSPDDRPTLPQL 500
+M+ CW P RP +L
Sbjct: 455 VLMSSCWEAEPARRPPFRKL 474
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 122 bits (294), Expect = 3e-27
Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 28/260 (10%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
EG FG V +G Y Q+V VK + V L E ++ + HE ++ +LGV
Sbjct: 243 EGEFGAVLQGEYLG-----QKVAVKNIK---CDVTAQAFLDETAVMTKMQHENLVRLLGV 294
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ Q ++ G N+ FL RG + + T +++ +LH +G
Sbjct: 295 ILH-QGLYIVMEHVSKG--NLVNFLRT-RGRAL-----------VNTAQLLQFSLHVAEG 339
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+ YL S+ ++H+D+AARN +V E+L ++D L++ A+ L D+ P+KW A E
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAK----AERKGL-DSSRLPVKWTAPE 394
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
AL +F+ +DVW+ GVLLWE+ + PY ++ EV+ + GYR++ P CP +
Sbjct: 395 ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVH 454
Query: 481 AVMAYCWAMSPDDRPTLPQL 500
+M+ CW P RP +L
Sbjct: 455 VLMSSCWEAEPARRPPFRKL 474
>L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase
protein.
Length = 879
Score = 122 bits (294), Expect = 3e-27
Identities = 86/287 (29%), Positives = 127/287 (44%), Gaps = 14/287 (4%)
Query: 228 IQRCRVRLRSVAMEGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLY 287
IQR R+ L EG FG V++G Y E V +KT S LQE C
Sbjct: 236 IQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEACHYT 295
Query: 288 GLHHE--RVLSVLGVSI--EDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXX-------- 335
LH R +S V + + A + +D + ++ V I
Sbjct: 296 SLHWNWCRYISDPNVDACPDPRNAELTMRQFDHPHIVKLIGVITENPVWIIMELCTLGEL 355
Query: 336 -XXXXXXXXXLTTQHVVRMALHALDGLLYLHSQHVLHKDIAARNCIVDENLRVMIADNAL 394
L ++ A L YL S+ +H+DIAARN +V N V + D L
Sbjct: 356 RSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGL 415
Query: 395 SRDLFPADYHCLGDNENRPIKWLALEALTKRQFSPAADVWALGVLLWELTTLAHQPYAEV 454
SR + + Y+ + PIKW+A E++ R+F+ A+DVW GV +WE+ +P+ V
Sbjct: 416 SRYMEDSTYYKASKGK-LPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGV 474
Query: 455 DPFEVAAYLRDGYRLQQPANCPDELFAVMAYCWAMSPDDRPTLPQLQ 501
+V + +G RL P NCP L+++M CWA P RP +L+
Sbjct: 475 KNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELK 521
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 122 bits (294), Expect = 3e-27
Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 28/260 (10%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
EG FG V +G Y Q+V VK + V L E ++ + HE ++ +LGV
Sbjct: 243 EGEFGAVLQGEYLG-----QKVAVKNIK---CDVTAQAFLDETAVMTKMQHENLVRLLGV 294
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ Q ++ G N+ FL RG + + T +++ +LH +G
Sbjct: 295 ILH-QGLYIVMEHVSKG--NLVNFLRT-RGRAL-----------VNTAQLLQFSLHVAEG 339
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+ YL S+ ++H+D+AARN +V E+L ++D L++ A+ L D+ P+KW A E
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAK----AERKGL-DSSRLPVKWTAPE 394
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
AL +F+ +DVW+ GVLLWE+ + PY ++ EV+ + GYR++ P CP +
Sbjct: 395 ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVH 454
Query: 481 AVMAYCWAMSPDDRPTLPQL 500
+M+ CW P RP +L
Sbjct: 455 VLMSSCWEAEPARRPPFRKL 474
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 122 bits (294), Expect = 3e-27
Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 28/260 (10%)
Query: 241 EGTFGRVYRGTYADEEAREQEVLVKTVAEHASQVQVSLLLQEGCMLYGLHHERVLSVLGV 300
EG FG V +G Y Q+V VK + V L E ++ + HE ++ +LGV
Sbjct: 243 EGEFGAVLQGEYLG-----QKVAVKNIK---CDVTAQAFLDETAVMTKMQHENLVRLLGV 294
Query: 301 SIEDQTAPFLLYPWDAGWRNMKLFLLACRGVTIXXXXXXXXXXXLTTQHVVRMALHALDG 360
+ Q ++ G N+ FL RG + + T +++ +LH +G
Sbjct: 295 ILH-QGLYIVMEHVSKG--NLVNFLRT-RGRAL-----------VNTAQLLQFSLHVAEG 339
Query: 361 LLYLHSQHVLHKDIAARNCIVDENLRVMIADNALSRDLFPADYHCLGDNENRPIKWLALE 420
+ YL S+ ++H+D+AARN +V E+L ++D L++ A+ L D+ P+KW A E
Sbjct: 340 MEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAK----AERKGL-DSSRLPVKWTAPE 394
Query: 421 ALTKRQFSPAADVWALGVLLWELTTLAHQPYAEVDPFEVAAYLRDGYRLQQPANCPDELF 480
AL +F+ +DVW+ GVLLWE+ + PY ++ EV+ + GYR++ P CP +
Sbjct: 395 ALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVH 454
Query: 481 AVMAYCWAMSPDDRPTLPQL 500
+M+ CW P RP +L
Sbjct: 455 VLMSSCWEAEPARRPPFRKL 474
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.135 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,625,848
Number of Sequences: 224733
Number of extensions: 2705757
Number of successful extensions: 9158
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1427
Number of HSP's successfully gapped in prelim test: 780
Number of HSP's that attempted gapping in prelim test: 5664
Number of HSP's gapped (non-prelim): 2641
length of query: 515
length of database: 73,234,838
effective HSP length: 93
effective length of query: 422
effective length of database: 52,334,669
effective search space: 22085230318
effective search space used: 22085230318
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 67 (31.1 bits)
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