Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002592-TA|BGIBMGA002592-PA|IPR002470|Peptidase S9A,
prolyl oligopeptidase, IPR004106|Peptidase S9A, prolyl oligopeptidase,
N-terminal beta-propeller
(189 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X74496-1|CAA52605.1| 710|Homo sapiens prolyl oligopeptidase pro... 274 2e-73
AB028867-1|BAB19053.1| 710|Homo sapiens prolyl oligopeptidase p... 274 2e-73
AB020018-1|BAA86936.1| 710|Homo sapiens prolyl endopeptidase pr... 274 2e-73
D21102-1|BAA04661.1| 710|Homo sapiens prolyl endopeptidase prot... 273 2e-73
BC030636-1|AAH30636.1| 710|Homo sapiens prolyl endopeptidase pr... 272 4e-73
AY660966-1|AAV70495.1| 710|Homo sapiens prolyl oligopeptidase p... 272 4e-73
AL590871-1|CAH72545.1| 710|Homo sapiens prolyl endopeptidase pr... 272 4e-73
AL139191-1|CAI21416.1| 710|Homo sapiens prolyl endopeptidase pr... 272 4e-73
AL133406-4|CAI42689.1| 710|Homo sapiens prolyl endopeptidase pr... 272 4e-73
AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein. 32 1.1
AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein. 32 1.1
D13643-1|BAA02806.3| 553|Homo sapiens KIAA0018 protein protein. 29 9.9
BC011669-1|AAH11669.1| 516|Homo sapiens 24-dehydrocholesterol r... 29 9.9
BC004375-1|AAH04375.1| 516|Homo sapiens 24-dehydrocholesterol r... 29 9.9
AF398342-1|AAL15644.1| 516|Homo sapiens 3beta-hydroxysterol del... 29 9.9
AF261758-1|AAG17288.1| 516|Homo sapiens seladin-1 protein. 29 9.9
AB073391-1|BAE45721.1| 427|Homo sapiens putative protein produc... 29 9.9
>X74496-1|CAA52605.1| 710|Homo sapiens prolyl oligopeptidase
protein.
Length = 710
Score = 274 bits (671), Expect = 2e-73
Identities = 121/185 (65%), Positives = 144/185 (77%)
Query: 3 YDYPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSI 62
+ YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++
Sbjct: 4 FQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLY 63
Query: 63 NERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDG 122
ER+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DG
Sbjct: 64 KERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDG 123
Query: 123 TVALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNK 182
TVAL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D K
Sbjct: 124 TVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGK 183
Query: 183 GLFYS 187
G+FY+
Sbjct: 184 GMFYN 188
>AB028867-1|BAB19053.1| 710|Homo sapiens prolyl oligopeptidase
protein.
Length = 710
Score = 274 bits (671), Expect = 2e-73
Identities = 121/185 (65%), Positives = 144/185 (77%)
Query: 3 YDYPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSI 62
+ YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++
Sbjct: 4 FQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLY 63
Query: 63 NERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDG 122
ER+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DG
Sbjct: 64 KERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDG 123
Query: 123 TVALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNK 182
TVAL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D K
Sbjct: 124 TVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGK 183
Query: 183 GLFYS 187
G+FY+
Sbjct: 184 GMFYN 188
>AB020018-1|BAA86936.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 274 bits (671), Expect = 2e-73
Identities = 121/185 (65%), Positives = 144/185 (77%)
Query: 3 YDYPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSI 62
+ YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++
Sbjct: 4 FQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLY 63
Query: 63 NERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDG 122
ER+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DG
Sbjct: 64 KERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDG 123
Query: 123 TVALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNK 182
TVAL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D K
Sbjct: 124 TVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGK 183
Query: 183 GLFYS 187
G+FY+
Sbjct: 184 GMFYN 188
>D21102-1|BAA04661.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 273 bits (670), Expect = 2e-73
Identities = 120/185 (64%), Positives = 144/185 (77%)
Query: 3 YDYPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSI 62
+ YP V RDET + DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++
Sbjct: 4 FQYPDVYRDETAIQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLY 63
Query: 63 NERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDG 122
ER+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DG
Sbjct: 64 KERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDG 123
Query: 123 TVALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNK 182
TVAL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D K
Sbjct: 124 TVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGK 183
Query: 183 GLFYS 187
G+FY+
Sbjct: 184 GMFYN 188
>BC030636-1|AAH30636.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 272 bits (668), Expect = 4e-73
Identities = 121/183 (66%), Positives = 143/183 (78%)
Query: 5 YPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSINE 64
YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++ E
Sbjct: 6 YPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKE 65
Query: 65 RLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDGTV 124
R+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DGTV
Sbjct: 66 RMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTV 125
Query: 125 ALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNKGL 184
AL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D KG+
Sbjct: 126 ALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGM 185
Query: 185 FYS 187
FY+
Sbjct: 186 FYN 188
>AY660966-1|AAV70495.1| 710|Homo sapiens prolyl oligopeptidase
protein.
Length = 710
Score = 272 bits (668), Expect = 4e-73
Identities = 121/183 (66%), Positives = 143/183 (78%)
Query: 5 YPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSINE 64
YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++ E
Sbjct: 6 YPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKE 65
Query: 65 RLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDGTV 124
R+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DGTV
Sbjct: 66 RMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTV 125
Query: 125 ALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNKGL 184
AL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D KG+
Sbjct: 126 ALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGM 185
Query: 185 FYS 187
FY+
Sbjct: 186 FYN 188
>AL590871-1|CAH72545.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 272 bits (668), Expect = 4e-73
Identities = 121/183 (66%), Positives = 143/183 (78%)
Query: 5 YPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSINE 64
YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++ E
Sbjct: 6 YPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKE 65
Query: 65 RLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDGTV 124
R+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DGTV
Sbjct: 66 RMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTV 125
Query: 125 ALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNKGL 184
AL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D KG+
Sbjct: 126 ALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGM 185
Query: 185 FYS 187
FY+
Sbjct: 186 FYN 188
>AL139191-1|CAI21416.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 272 bits (668), Expect = 4e-73
Identities = 121/183 (66%), Positives = 143/183 (78%)
Query: 5 YPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSINE 64
YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++ E
Sbjct: 6 YPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKE 65
Query: 65 RLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDGTV 124
R+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DGTV
Sbjct: 66 RMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTV 125
Query: 125 ALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNKGL 184
AL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D KG+
Sbjct: 126 ALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGM 185
Query: 185 FYS 187
FY+
Sbjct: 186 FYN 188
>AL133406-4|CAI42689.1| 710|Homo sapiens prolyl endopeptidase
protein.
Length = 710
Score = 272 bits (668), Expect = 4e-73
Identities = 121/183 (66%), Positives = 143/183 (78%)
Query: 5 YPAVRRDETVVDDYHGTKIKDPYRWLEDPDSNETKEFVEAQNKITRPYLDACPVQKSINE 64
YP V RDET V DYHG KI DPY WLEDPDS +TK FVEAQNKIT P+L+ CP++ E
Sbjct: 6 YPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKE 65
Query: 65 RLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRVFLDPNTLSEDGTV 124
R+TEL++YPKYSC F+KG RYF+F NTGLQNQ LYVQD L+GE RVFLDPN LS+DGTV
Sbjct: 66 RMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTV 125
Query: 125 ALSGTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPEVLEKVKFASMSWTKDNKGL 184
AL G F+EDG AYGLSASGSDW+ I F V ++ P+VLE+VKF+ M+WT D KG+
Sbjct: 126 ALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGM 185
Query: 185 FYS 187
FY+
Sbjct: 186 FYN 188
>AF376802-1|AAM46111.1| 835|Homo sapiens neuroligin 2 protein.
Length = 835
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 128 GTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPE----VLEKVKFASMSWTKDNKG 183
G KF ED + G+SAS D+ +F D G YPE + E +KF W + G
Sbjct: 387 GLKFVEDSAESEDGVSASAFDFTVSNFVDNLYG--YPEGKDVLRETIKFMYTDWADRDNG 444
>AB037787-1|BAA92604.1| 550|Homo sapiens KIAA1366 protein protein.
Length = 550
Score = 32.3 bits (70), Expect = 1.1
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 6/60 (10%)
Query: 128 GTKFTEDGSTLAYGLSASGSDWIAIHFKDVATGEDYPE----VLEKVKFASMSWTKDNKG 183
G KF ED + G+SAS D+ +F D G YPE + E +KF W + G
Sbjct: 102 GLKFVEDSAESEDGVSASAFDFTVSNFVDNLYG--YPEGKDVLRETIKFMYTDWADRDNG 159
>D13643-1|BAA02806.3| 553|Homo sapiens KIAA0018 protein protein.
Length = 553
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 431 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 482
>BC011669-1|AAH11669.1| 516|Homo sapiens 24-dehydrocholesterol
reductase protein.
Length = 516
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 394 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 445
>BC004375-1|AAH04375.1| 516|Homo sapiens 24-dehydrocholesterol
reductase protein.
Length = 516
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 394 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 445
>AF398342-1|AAL15644.1| 516|Homo sapiens 3beta-hydroxysterol delta
24 reductase protein.
Length = 516
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 394 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 445
>AF261758-1|AAG17288.1| 516|Homo sapiens seladin-1 protein.
Length = 516
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 394 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 445
>AB073391-1|BAE45721.1| 427|Homo sapiens putative protein product
of Nbla03646 protein.
Length = 427
Score = 29.1 bits (62), Expect = 9.9
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%)
Query: 58 VQKSINERLTELWNYPKYSCPFRKGSRYFFFKNTGLQNQNALYVQDGLDGEPRV 111
+Q++++ ++ YP + CPF S+ G N+ LY+ G GEPRV
Sbjct: 305 LQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKG--NEAELYIDIGAYGEPRV 356
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.134 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 30,642,304
Number of Sequences: 224733
Number of extensions: 1272274
Number of successful extensions: 1527
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1518
Number of HSP's gapped (non-prelim): 17
length of query: 189
length of database: 73,234,838
effective HSP length: 86
effective length of query: 103
effective length of database: 53,907,800
effective search space: 5552503400
effective search space used: 5552503400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 62 (29.1 bits)
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