Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002591-TA|BGIBMGA002591-PA|IPR002290|Serine/threonine
protein kinase, IPR000719|Protein kinase, IPR011009|Protein
kinase-like, IPR008271|Serine/threonine protein kinase, active site,
IPR000194|ATPase, F1/V1/A1 complex, alpha/beta subunit,
nucleotide-binding, IPR005479|Carbamoyl-phosphate synthase L chain,
ATP-binding
(1130 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 295 8e-79
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 295 8e-79
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 294 1e-78
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 294 1e-78
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 288 7e-77
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 158 9e-38
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 154 1e-36
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 154 1e-36
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 154 1e-36
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 152 8e-36
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 151 1e-35
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 151 1e-35
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 151 1e-35
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 151 1e-35
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 149 4e-35
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 149 4e-35
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 149 7e-35
BC050565-1|AAH50565.1| 1143|Homo sapiens PASK protein protein. 148 1e-34
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 148 1e-34
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 148 1e-34
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 147 2e-34
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 147 2e-34
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 147 2e-34
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 147 2e-34
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 147 2e-34
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 147 2e-34
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 145 9e-34
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 145 9e-34
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 145 9e-34
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 145 9e-34
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 145 9e-34
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 145 9e-34
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 145 9e-34
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 144 1e-33
BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein. 144 2e-33
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 144 2e-33
AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase... 144 2e-33
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 143 4e-33
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 143 4e-33
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 143 4e-33
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 142 5e-33
DQ022562-1|AAY87461.1| 404|Homo sapiens pim-1 kinase 44 kDa iso... 142 5e-33
M54915-1|AAA36447.1| 313|Homo sapiens pim-1 protein protein. 142 6e-33
M27903-1|AAA60090.1| 313|Homo sapiens protein ( Human pim-1 pro... 142 6e-33
M24779-1|AAA81553.1| 313|Homo sapiens protein kinase protein. 142 6e-33
M16750-1|AAA60089.1| 313|Homo sapiens pim-1 protein protein. 142 6e-33
BC020224-1|AAH20224.1| 313|Homo sapiens pim-1 oncogene protein. 142 6e-33
AL353579-1|CAI20316.1| 313|Homo sapiens pim-1 oncogene protein. 142 6e-33
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 140 3e-32
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 140 3e-32
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 140 3e-32
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 139 4e-32
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 139 4e-32
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 139 4e-32
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 139 4e-32
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 139 6e-32
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 139 6e-32
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 139 6e-32
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 139 6e-32
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 139 6e-32
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 138 1e-31
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 138 1e-31
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 138 1e-31
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 138 1e-31
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 137 2e-31
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 136 6e-31
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 136 6e-31
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 135 7e-31
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 134 1e-30
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 134 2e-30
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 134 2e-30
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 134 2e-30
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 134 2e-30
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 134 2e-30
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 133 3e-30
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 133 3e-30
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 133 4e-30
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 133 4e-30
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 133 4e-30
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 133 4e-30
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 130 4e-29
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 125 1e-27
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 123 3e-27
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 123 3e-27
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 123 3e-27
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 123 3e-27
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 123 3e-27
U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homol... 120 3e-26
BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein. 120 3e-26
AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene hom... 120 3e-26
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 120 4e-26
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 120 4e-26
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 117 3e-25
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 117 3e-25
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 117 3e-25
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 117 3e-25
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 117 3e-25
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 117 3e-25
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 117 3e-25
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 117 3e-25
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 117 3e-25
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 116 5e-25
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 116 5e-25
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 116 5e-25
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 116 5e-25
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 116 6e-25
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 116 6e-25
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 116 6e-25
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 116 6e-25
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 115 8e-25
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 115 1e-24
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 115 1e-24
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 115 1e-24
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 115 1e-24
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 114 1e-24
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 114 1e-24
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 114 1e-24
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 113 3e-24
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 113 4e-24
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 113 4e-24
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 113 4e-24
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 113 4e-24
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 112 8e-24
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 112 8e-24
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 112 8e-24
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 112 8e-24
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 112 8e-24
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 111 1e-23
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 111 1e-23
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 111 1e-23
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 111 1e-23
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 111 1e-23
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 111 1e-23
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 111 2e-23
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 110 3e-23
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 110 3e-23
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 110 3e-23
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 110 3e-23
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 110 3e-23
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 110 3e-23
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 110 3e-23
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 110 3e-23
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 110 3e-23
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 110 3e-23
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 110 3e-23
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 110 3e-23
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 109 4e-23
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 109 4e-23
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 108 1e-22
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 108 1e-22
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 108 1e-22
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 107 2e-22
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 107 2e-22
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 107 2e-22
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 107 2e-22
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 107 2e-22
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 107 3e-22
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 107 3e-22
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 107 3e-22
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 107 3e-22
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 106 4e-22
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 105 7e-22
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 105 7e-22
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 105 7e-22
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 105 7e-22
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 105 7e-22
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 105 7e-22
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 105 9e-22
U43784-1|AAC50428.1| 382|Homo sapiens mitogen activated protein... 105 1e-21
U09578-1|AAD09136.1| 382|Homo sapiens MAPKAP kinase protein. 105 1e-21
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 105 1e-21
BC010407-1|AAH10407.1| 382|Homo sapiens mitogen-activated prote... 105 1e-21
BC007591-1|AAH07591.1| 382|Homo sapiens mitogen-activated prote... 105 1e-21
BC001662-1|AAH01662.1| 382|Homo sapiens mitogen-activated prote... 105 1e-21
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 105 1e-21
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 105 1e-21
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 105 1e-21
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 105 1e-21
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 105 1e-21
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 104 2e-21
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 103 3e-21
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 103 3e-21
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 103 3e-21
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 103 3e-21
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 103 4e-21
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 102 6e-21
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 102 8e-21
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 102 8e-21
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 102 8e-21
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 101 1e-20
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 101 1e-20
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 101 1e-20
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 101 1e-20
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 101 1e-20
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 101 2e-20
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 101 2e-20
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 101 2e-20
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 101 2e-20
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 101 2e-20
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 101 2e-20
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 101 2e-20
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 101 2e-20
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 100 3e-20
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 100 3e-20
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 99 1e-19
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 99 1e-19
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 99 1e-19
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 99 1e-19
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 99 1e-19
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 99 1e-19
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 99 1e-19
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 98 2e-19
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 98 2e-19
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 98 2e-19
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 97 2e-19
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 97 2e-19
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 97 2e-19
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 97 2e-19
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 97 2e-19
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 97 2e-19
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 97 2e-19
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 97 2e-19
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 97 2e-19
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 97 2e-19
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 97 3e-19
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 97 3e-19
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 97 3e-19
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 97 3e-19
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 97 3e-19
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 97 3e-19
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 97 3e-19
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 97 3e-19
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 97 3e-19
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 97 3e-19
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 97 3e-19
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 97 3e-19
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 97 4e-19
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 96 5e-19
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 96 5e-19
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 96 5e-19
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 96 5e-19
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 96 7e-19
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 96 7e-19
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 96 7e-19
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 95 1e-18
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 95 1e-18
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 95 1e-18
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 95 1e-18
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 95 1e-18
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 95 1e-18
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 95 1e-18
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 95 1e-18
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 95 1e-18
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 95 1e-18
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 95 1e-18
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 95 1e-18
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 95 1e-18
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 95 2e-18
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 95 2e-18
AF262405-1|AAF72667.1| 871|Homo sapiens calcium/calmodulin-depe... 95 2e-18
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 94 2e-18
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 94 2e-18
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 94 2e-18
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 94 2e-18
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 94 2e-18
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 94 2e-18
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 94 2e-18
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 94 3e-18
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 94 3e-18
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 94 3e-18
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 94 3e-18
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 94 3e-18
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 94 3e-18
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 93 4e-18
X75346-1|CAA53094.1| 396|Homo sapiens MAP kinase activated prot... 93 4e-18
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 93 4e-18
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 93 4e-18
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 93 4e-18
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 93 4e-18
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 93 4e-18
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 93 4e-18
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 93 5e-18
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 93 5e-18
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 93 7e-18
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 93 7e-18
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 93 7e-18
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 93 7e-18
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 93 7e-18
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 91 2e-17
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 91 2e-17
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 91 2e-17
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 91 2e-17
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 91 2e-17
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 91 2e-17
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 91 2e-17
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 91 2e-17
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 91 2e-17
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 91 2e-17
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 91 2e-17
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 91 2e-17
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 91 3e-17
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 91 3e-17
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 91 3e-17
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 91 3e-17
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 91 3e-17
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 91 3e-17
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 91 3e-17
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 91 3e-17
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 91 3e-17
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 91 3e-17
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 91 3e-17
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 90 4e-17
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 90 4e-17
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 90 4e-17
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 90 4e-17
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 90 4e-17
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 90 4e-17
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 90 4e-17
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 90 5e-17
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 90 5e-17
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 90 5e-17
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 90 5e-17
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 90 5e-17
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 90 5e-17
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 89 6e-17
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 89 6e-17
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 89 6e-17
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 89 6e-17
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 89 6e-17
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 89 6e-17
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 89 6e-17
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 89 6e-17
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 89 6e-17
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 89 8e-17
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 89 8e-17
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 89 8e-17
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 89 8e-17
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 89 8e-17
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 89 8e-17
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 89 8e-17
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 89 8e-17
BC017268-1|AAH17268.1| 383|Homo sapiens TRIO protein protein. 89 8e-17
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 89 8e-17
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 89 8e-17
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 89 8e-17
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 89 8e-17
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 89 8e-17
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 89 8e-17
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 89 8e-17
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 89 8e-17
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 89 8e-17
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 89 1e-16
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 88 1e-16
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 88 1e-16
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 88 2e-16
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 88 2e-16
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 88 2e-16
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 88 2e-16
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 88 2e-16
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 88 2e-16
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 88 2e-16
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 88 2e-16
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 88 2e-16
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 88 2e-16
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 87 3e-16
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 87 3e-16
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 87 3e-16
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 87 3e-16
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 87 3e-16
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 87 3e-16
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 87 3e-16
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 87 4e-16
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 87 4e-16
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 87 4e-16
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 87 4e-16
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 87 4e-16
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 87 4e-16
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 87 4e-16
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 87 4e-16
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 86 6e-16
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 86 8e-16
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 86 8e-16
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 86 8e-16
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 85 1e-15
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 85 1e-15
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 85 1e-15
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 85 1e-15
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 85 1e-15
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 85 1e-15
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 85 2e-15
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 85 2e-15
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 85 2e-15
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 85 2e-15
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 85 2e-15
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 85 2e-15
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 85 2e-15
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 85 2e-15
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 84 2e-15
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 84 2e-15
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 84 2e-15
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 84 2e-15
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 84 2e-15
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 84 2e-15
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 84 2e-15
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 84 2e-15
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 84 2e-15
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 84 2e-15
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 84 2e-15
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 84 2e-15
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 84 2e-15
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 84 2e-15
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 84 2e-15
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 84 2e-15
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 84 2e-15
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 84 2e-15
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 84 2e-15
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 84 2e-15
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 84 2e-15
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 84 2e-15
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 84 2e-15
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 84 3e-15
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 83 4e-15
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 83 4e-15
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 83 4e-15
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 83 4e-15
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 83 4e-15
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 83 4e-15
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 83 4e-15
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 83 4e-15
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 83 4e-15
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 83 4e-15
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 83 4e-15
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 83 4e-15
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 83 4e-15
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 83 4e-15
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 83 4e-15
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 83 4e-15
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 83 4e-15
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 83 4e-15
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 295 bits (723), Expect = 8e-79
Identities = 167/437 (38%), Positives = 242/437 (55%), Gaps = 16/437 (3%)
Query: 600 PCVPKRLLRAHVTSTPQNTRDRPADTCAADCRHRDGTYRGVVMHRDGTELNVVYTVSSMQ 659
P + L VTSTP A ++G Y G HRDG L++ + V ++
Sbjct: 860 PSAEEPRLNVQVTSTPVIVMRGAA---GLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVE 916
Query: 660 LAGGRSVRCVWLGVQL-----EDAPRHNTVASSLT-STADNSLVLGNKSA----GSRP-- 707
L G + C WL L + A R +SL ST + L S +RP
Sbjct: 917 LQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWF 976
Query: 708 -QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
+ V G GEYS+ Y T+ +G GA+G V A + V KFI KEK+
Sbjct: 977 EEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVL 1036
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
++ P KV LE+++L ++H NI+ ++D++EN+ +FQ+VMEKHG+G+DLF FI+R
Sbjct: 1037 EDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDR 1096
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
PR+DEPL SYIFRQ+ AV YL +I+HR F +KLIDFGSA ++ +
Sbjct: 1097 HPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERG 1156
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTF 946
LF TF GT EYC+PEVL GN Y GPELEMWS+G+TLY L F +PF ++E+T++ +
Sbjct: 1157 KLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHP 1216
Query: 947 PHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDCDRDEANPE 1006
P+LVS++L L+ +L P R T+ +L++ PW+ Q V +A+Y + E+ ++ E+
Sbjct: 1217 PYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVL 1276
Query: 1007 MYYNGSLSPRSGSPVDQ 1023
+ + RS S V Q
Sbjct: 1277 SAASLEMGNRSLSDVAQ 1293
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/210 (29%), Positives = 108/210 (51%), Gaps = 10/210 (4%)
Query: 67 VVELQTKEGGTVQVSLWIRQLDSDGP--CLVVAEPVNCKNVLLTIDAETAVILSCEGVDA 124
VV++ ++ G + VS+W++++ + C+VV EPV + + ++ + SC+ + A
Sbjct: 200 VVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSD-GTVTSCDSLFA 258
Query: 125 PALFGAESCDKLVGLPITSLIPSIRLPAVDTPISKSMAKQKVTGRTLEGGCFPVCLWITK 184
L G S + + G IT LIPS++LP I K++ Q+ GR +G FP+ L +
Sbjct: 259 H-LHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKS 317
Query: 185 PDNSDGAHWSAIKSQRSILEINLRVTYNVSGLLVVDEAGIITACNHHFAMLTFGKPHSEV 244
+S+ A + + S ++ V +SGL+ + G I NH FA+ FG +E+
Sbjct: 318 QPSSEEA-TTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTEL 376
Query: 245 IGHHIDDVIQFFCRESDI-----VKLPDRA 269
+G +I +I F D+ ++LPD A
Sbjct: 377 LGKNITFLIPGFYSYMDLAYNSSLQLPDLA 406
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 295 bits (723), Expect = 8e-79
Identities = 167/437 (38%), Positives = 242/437 (55%), Gaps = 16/437 (3%)
Query: 600 PCVPKRLLRAHVTSTPQNTRDRPADTCAADCRHRDGTYRGVVMHRDGTELNVVYTVSSMQ 659
P + L VTSTP A ++G Y G HRDG L++ + V ++
Sbjct: 490 PSAEEPRLNVQVTSTPVIVMRGAA---GLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVE 546
Query: 660 LAGGRSVRCVWLGVQL-----EDAPRHNTVASSLT-STADNSLVLGNKSA----GSRP-- 707
L G + C WL L + A R +SL ST + L S +RP
Sbjct: 547 LQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWF 606
Query: 708 -QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
+ V G GEYS+ Y T+ +G GA+G V A + V KFI KEK+
Sbjct: 607 EEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVL 666
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
++ P KV LE+++L ++H NI+ ++D++EN+ +FQ+VMEKHG+G+DLF FI+R
Sbjct: 667 EDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDR 726
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
PR+DEPL SYIFRQ+ AV YL +I+HR F +KLIDFGSA ++ +
Sbjct: 727 HPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERG 786
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTF 946
LF TF GT EYC+PEVL GN Y GPELEMWS+G+TLY L F +PF ++E+T++ +
Sbjct: 787 KLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHP 846
Query: 947 PHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDCDRDEANPE 1006
P+LVS++L L+ +L P R T+ +L++ PW+ Q V +A+Y + E+ ++ E+
Sbjct: 847 PYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVFRVNKPESGVL 906
Query: 1007 MYYNGSLSPRSGSPVDQ 1023
+ + RS S V Q
Sbjct: 907 SAASLEMGNRSLSDVAQ 923
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 294 bits (721), Expect = 1e-78
Identities = 159/404 (39%), Positives = 233/404 (57%), Gaps = 13/404 (3%)
Query: 633 RDGTYRGVVMHRDGTELNVVYTVSSMQLAGGRSVRCVWLGVQL-----EDAPRHNTVASS 687
++G Y G HRDG L++ + V ++L G + C WL L + A R +S
Sbjct: 25 QEGAYSGSCYHRDGLRLSIQFEVRRVELQGPTPLFCCWLVKDLLHSQRDSAARTRLFLAS 84
Query: 688 LT-STADNSLVLGNKSA----GSRP---QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
L ST + L S +RP + V G GEYS+ Y T+ +G GA
Sbjct: 85 LPGSTHSTAAELTGPSLVEVLRARPWFEEPPKAVELEGLAACEGEYSQKYSTMSPLGSGA 144
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+G V A + V KFI KEK+ ++ P KV LE+++L ++H NI+ ++D
Sbjct: 145 FGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHANIIKVLD 204
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXX 859
++EN+ +FQ+VMEKHG+G+DLF FI+R PR+DEPL SYIFRQ+ AV YL +I+HR
Sbjct: 205 IFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDF 264
Query: 860 XXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSM 919
F +KLIDFGSA ++ + LF TF GT EYC+PEVL GN Y GPELEMWS+
Sbjct: 265 KDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSL 324
Query: 920 GITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHP 979
G+TLY L F +PF ++E+T++ + P+LVS++L L+ +L P R T+ +L++ P
Sbjct: 325 GVTLYTLVFEENPFCELEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDP 384
Query: 980 WIKQHVAIANYVFHEIIDCDRDEANPEMYYNGSLSPRSGSPVDQ 1023
W+ Q V +A+Y + E+ ++ E+ + + RS S V Q
Sbjct: 385 WVTQPVNLADYTWEEVFRVNKPESGVLSAASLEMGNRSLSDVAQ 428
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 294 bits (721), Expect = 1e-78
Identities = 167/437 (38%), Positives = 242/437 (55%), Gaps = 16/437 (3%)
Query: 600 PCVPKRLLRAHVTSTPQNTRDRPADTCAADCRHRDGTYRGVVMHRDGTELNVVYTVSSMQ 659
P + L VTSTP A ++G Y G HRDG L++ + V ++
Sbjct: 860 PSAEEPRLNVQVTSTPVIVMRGAA---GLQREIQEGAYSGSCHHRDGLRLSIQFEVRRVE 916
Query: 660 LAGGRSVRCVWLGVQL-----EDAPRHNTVASSLT-STADNSLVLGNKSA----GSRP-- 707
L G + C WL L + A R +SL ST + L S +RP
Sbjct: 917 LQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWF 976
Query: 708 -QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
+ V G GEYS+ Y T+ +G GA+G V A + V KFI KEK+
Sbjct: 977 EEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVL 1036
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
++ P KV LE+++L ++H NI+ ++D++EN+ +FQ+VMEKHG+G+DLF FI+R
Sbjct: 1037 EDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDR 1096
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
PR+DEPL SYIFRQ+ AV YL +I+HR F +KLIDFGSA ++ +
Sbjct: 1097 HPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERG 1156
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTF 946
LF TF GT EYC+PEVL GN Y GPELEMWS+G+TLY L F +PF ++E+T++ +
Sbjct: 1157 KLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEETVEAAIHP 1216
Query: 947 PHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDCDRDEANPE 1006
P+LVS++L L+ +L P R T+ +L++ PW+ Q V +A+Y + E+ ++ E+
Sbjct: 1217 PYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVCRVNKPESGVL 1276
Query: 1007 MYYNGSLSPRSGSPVDQ 1023
+ + RS S V Q
Sbjct: 1277 SAASLEMGNRSLSDVAQ 1293
Score = 84.2 bits (199), Expect = 2e-15
Identities = 61/210 (29%), Positives = 108/210 (51%), Gaps = 10/210 (4%)
Query: 67 VVELQTKEGGTVQVSLWIRQLDSDGP--CLVVAEPVNCKNVLLTIDAETAVILSCEGVDA 124
VV++ ++ G + VS+W++++ + C+VV EPV + + ++ + SC+ + A
Sbjct: 200 VVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSD-GTVTSCDSLFA 258
Query: 125 PALFGAESCDKLVGLPITSLIPSIRLPAVDTPISKSMAKQKVTGRTLEGGCFPVCLWITK 184
L G S + + G IT LIPS++LP I K++ Q+ GR +G FP+ L +
Sbjct: 259 H-LHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKS 317
Query: 185 PDNSDGAHWSAIKSQRSILEINLRVTYNVSGLLVVDEAGIITACNHHFAMLTFGKPHSEV 244
+S+ A + + S ++ V +SGL+ + G I NH FA+ FG +E+
Sbjct: 318 QPSSEEA-TTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTEL 376
Query: 245 IGHHIDDVIQFFCRESDI-----VKLPDRA 269
+G +I +I F D+ ++LPD A
Sbjct: 377 LGKNITFLIPGFYSYMDLAYNSSLQLPDLA 406
>D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein.
Length = 1351
Score = 288 bits (707), Expect = 7e-77
Identities = 170/444 (38%), Positives = 244/444 (54%), Gaps = 23/444 (5%)
Query: 600 PCVPKRLLRAHVTSTPQNTRDRPADTCAADCRHRDGTYRGVVMHRDGTELNVVYTVSSMQ 659
P + L VTSTP A ++G Y G HRDG L++ + V ++
Sbjct: 881 PSAEEPRLNVQVTSTPVIVMRGAA---GLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVE 937
Query: 660 LAGGRSVRCVWLGVQL-----EDAPRHNTVASSLT-STADNSLVLGNKSA----GSRP-- 707
L G + C WL L + A R +SL ST + L S +RP
Sbjct: 938 LQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWF 997
Query: 708 -QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
+ V G GEYS+ Y T+ +G GA+G V A + V KFI KEK+
Sbjct: 998 EEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVL 1057
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
++ P KV LE+++L ++H NI+ ++D++EN+ +FQ+VMEKHG+G+DLF FI+R
Sbjct: 1058 EDCWIEDPKLGKVTLEIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDR 1117
Query: 827 RPRMDEPLLSYIFRQV--GQ-----AVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGS 879
PR+DEPL SYIFRQV GQ AV YL +I+HR F +KLIDFGS
Sbjct: 1118 HPRLDEPLASYIFRQVRAGQSRLVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGS 1177
Query: 880 ATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDT 939
A ++ + LF TF GT EYC+PEVL GN Y GPELEMWS+G+TLY L F +PF ++E+T
Sbjct: 1178 AAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTLYTLVFEENPFCELEET 1237
Query: 940 IQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDCD 999
++ + P+LVS++L L+ +L P R T+ +L++ PW+ Q V +A+Y + E+ +
Sbjct: 1238 VEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKLVTDPWVTQPVNLADYTWEEVCRVN 1297
Query: 1000 RDEANPEMYYNGSLSPRSGSPVDQ 1023
+ E+ + + RS S V Q
Sbjct: 1298 KPESGVLSAASLEMGNRSLSDVAQ 1321
Score = 85.8 bits (203), Expect = 8e-16
Identities = 62/210 (29%), Positives = 108/210 (51%), Gaps = 10/210 (4%)
Query: 67 VVELQTKEGGTVQVSLWIRQLDSDGP--CLVVAEPVNCKNVLLTIDAETAVILSCEGVDA 124
VV++ T+ G + VS+W++++ + C+VV EPV + + ++ + SC+ + A
Sbjct: 221 VVDIITRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSD-GTVTSCDSLFA 279
Query: 125 PALFGAESCDKLVGLPITSLIPSIRLPAVDTPISKSMAKQKVTGRTLEGGCFPVCLWITK 184
L G S + + G IT LIPS++LP I K++ Q+ GR +G FP+ L +
Sbjct: 280 H-LHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKS 338
Query: 185 PDNSDGAHWSAIKSQRSILEINLRVTYNVSGLLVVDEAGIITACNHHFAMLTFGKPHSEV 244
+S+ A + + S ++ V +SGL+ + G I NH FA+ FG +E+
Sbjct: 339 QPSSEEA-TTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTEL 397
Query: 245 IGHHIDDVIQFFCRESDI-----VKLPDRA 269
+G +I +I F D+ ++LPD A
Sbjct: 398 LGKNITFLIPGFYSYMDLAYNSSLQLPDLA 427
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 158 bits (384), Expect = 9e-38
Identities = 89/277 (32%), Positives = 141/277 (50%), Gaps = 19/277 (6%)
Query: 716 GGDEQVAGEYSKH------YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
GG+E+ A E +H Y K +GKG G VK+ K + +EK+
Sbjct: 31 GGEEEEAEERGRHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESV 90
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 91 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 143
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 144 LTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 203
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G +MWS G+ L+ L PF D +E +G
Sbjct: 204 ETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 263
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M+ +P R ++ Q+ HPW
Sbjct: 264 FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 300
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 154 bits (374), Expect = 1e-36
Identities = 84/263 (31%), Positives = 134/263 (50%), Gaps = 13/263 (4%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
+Y Y K +GKG G VK+ K + +EK+ L+ KV E+
Sbjct: 29 QYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM------KVEREI 82
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+ FRQ+
Sbjct: 83 AILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFFRQIV 141
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
A+++ HS +I HR ++++ DFG A+ DSL T G+ Y PEV
Sbjct: 142 SALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEV 201
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
+ G KY G +MWS G+ L+ L PF D +E +G PH + D + L
Sbjct: 202 IKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSL 261
Query: 958 LRWMLCKDPANRCTITQLMSHPW 980
LR M+ +P R ++ Q+ HPW
Sbjct: 262 LRGMIEVEPEKRLSLEQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 154 bits (374), Expect = 1e-36
Identities = 84/263 (31%), Positives = 134/263 (50%), Gaps = 13/263 (4%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
+Y Y K +GKG G VK+ K + +EK+ L+ KV E+
Sbjct: 29 QYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM------KVEREI 82
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+ FRQ+
Sbjct: 83 AILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFFRQIV 141
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
A+++ HS +I HR ++++ DFG A+ DSL T G+ Y PEV
Sbjct: 142 SALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEV 201
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
+ G KY G +MWS G+ L+ L PF D +E +G PH + D + L
Sbjct: 202 IKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSL 261
Query: 958 LRWMLCKDPANRCTITQLMSHPW 980
LR M+ +P R ++ Q+ HPW
Sbjct: 262 LRGMIEVEPEKRLSLEQIQKHPW 284
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 154 bits (374), Expect = 1e-36
Identities = 84/263 (31%), Positives = 134/263 (50%), Gaps = 13/263 (4%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
+Y Y K +GKG G VK+ K + +EK+ L+ KV E+
Sbjct: 29 QYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLM------KVEREI 82
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+ FRQ+
Sbjct: 83 AILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFFRQIV 141
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
A+++ HS +I HR ++++ DFG A+ DSL T G+ Y PEV
Sbjct: 142 SALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEV 201
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
+ G KY G +MWS G+ L+ L PF D +E +G PH + D + L
Sbjct: 202 IKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSL 261
Query: 958 LRWMLCKDPANRCTITQLMSHPW 980
LR M+ +P R ++ Q+ HPW
Sbjct: 262 LRGMIEVEPEKRLSLEQIQKHPW 284
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 152 bits (368), Expect = 8e-36
Identities = 86/262 (32%), Positives = 131/262 (50%), Gaps = 14/262 (5%)
Query: 727 KHYVTLKQ-IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
KH L++ +GKG YG VK A R + K I K+KI D D + E+ +
Sbjct: 89 KHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIK-----DEQDMVHIRREIEI 143
Query: 786 LLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQA 845
+ +L HP+I+S+ +V+EN+ ++ME G +L+++I R R+ E + FRQ+ A
Sbjct: 144 MSSLNHPHIISIYEVFENKDKIVIIMEYASKG-ELYDYISERRRLSERETRHFFRQIVSA 202
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
V Y H ++HR ++K+ DFG + KD TF G+ Y SPE++
Sbjct: 203 VHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVN 262
Query: 906 GNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLR 959
G Y GPE++ W++G+ LY L + PF I G P S D L+R
Sbjct: 263 GRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPS-DARGLIR 321
Query: 960 WMLCKDPANRCTITQLMSHPWI 981
WML +P R TI + +H W+
Sbjct: 322 WMLMVNPDRRATIEDIANHWWV 343
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 151 bits (367), Expect = 1e-35
Identities = 101/307 (32%), Positives = 149/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG +
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNF 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 125 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 183
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 184 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 244 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
Query: 975 LMSHPWI 981
+M WI
Sbjct: 304 IMKDKWI 310
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 151 bits (367), Expect = 1e-35
Identities = 101/307 (32%), Positives = 149/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG +
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNF 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 125 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 183
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 184 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 244 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
Query: 975 LMSHPWI 981
+M WI
Sbjct: 304 IMKDKWI 310
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 151 bits (367), Expect = 1e-35
Identities = 101/307 (32%), Positives = 149/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG +
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNF 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 125 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 183
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 184 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 244 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
Query: 975 LMSHPWI 981
+M WI
Sbjct: 304 IMKDKWI 310
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 151 bits (367), Expect = 1e-35
Identities = 101/307 (32%), Positives = 149/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG +
Sbjct: 19 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNF 71
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 72 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 125
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 126 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 184
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 185 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 244
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 245 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 304
Query: 975 LMSHPWI 981
+M WI
Sbjct: 305 IMKDKWI 311
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 149 bits (362), Expect = 4e-35
Identities = 101/307 (32%), Positives = 148/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNS 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 125 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 183
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 184 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 244 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
Query: 975 LMSHPWI 981
+M WI
Sbjct: 304 IMKDKWI 310
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 149 bits (362), Expect = 4e-35
Identities = 101/307 (32%), Positives = 148/307 (48%), Gaps = 20/307 (6%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNS 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXX 860
E EK +VME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 125 IETEKTLYLVMEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLK 183
Query: 861 XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMG 920
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G
Sbjct: 184 AENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLG 243
Query: 921 ITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQ 974
+ LY L PF E ++G P +S D E +LR L +PA RCT+ Q
Sbjct: 244 VILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQ 303
Query: 975 LMSHPWI 981
+M WI
Sbjct: 304 IMKDKWI 310
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 149 bits (360), Expect = 7e-35
Identities = 87/277 (31%), Positives = 139/277 (50%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M+ D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIW 269
>BC050565-1|AAH50565.1| 1143|Homo sapiens PASK protein protein.
Length = 1143
Score = 148 bits (358), Expect = 1e-34
Identities = 94/256 (36%), Positives = 133/256 (51%), Gaps = 16/256 (6%)
Query: 600 PCVPKRLLRAHVTSTPQNTRDRPADTCAADCRHRDGTYRGVVMHRDGTELNVVYTVSSMQ 659
P + L VTSTP A ++G Y G HRDG L++ + V ++
Sbjct: 860 PSAEEPRLNVQVTSTPVIVMRGAA---GLQREIQEGAYSGSCYHRDGLRLSIQFEVRRVE 916
Query: 660 LAGGRSVRCVWLGVQL-----EDAPRHNTVASSLT-STADNSLVLGNKSA----GSRP-- 707
L G + C WL L + A R +SL ST + L S +RP
Sbjct: 917 LQGPTPLFCCWLVKDLLHSQRDSAARTRLFLASLPGSTHSTAAELTGPSLVEVLRARPWF 976
Query: 708 -QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
+ V G GEYS+ Y T+ +G GA+G V A + V KFI KEK+
Sbjct: 977 EEPPKAVELEGLAACEGEYSQKYSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVL 1036
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
++ P KV LE+++L ++H NI+ ++D++EN+ +FQ+VMEKHG+G+DLF FI+R
Sbjct: 1037 EDCWIEDPKLGKVTLEIAILSRVEHSNIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDR 1096
Query: 827 RPRMDEPLLSYIFRQV 842
PR+DEPL SYIFRQV
Sbjct: 1097 HPRLDEPLASYIFRQV 1112
Score = 84.6 bits (200), Expect = 2e-15
Identities = 62/210 (29%), Positives = 108/210 (51%), Gaps = 10/210 (4%)
Query: 67 VVELQTKEGGTVQVSLWIRQLDSDGP--CLVVAEPVNCKNVLLTIDAETAVILSCEGVDA 124
VV++ ++ G + VS+W++++ + C+VV EPV + + ++ I SC+ + A
Sbjct: 200 VVDIISRSGEKIPVSVWMKRMRQERRLCCVVVLEPVERVSTWVAFQSD-GTITSCDSLFA 258
Query: 125 PALFGAESCDKLVGLPITSLIPSIRLPAVDTPISKSMAKQKVTGRTLEGGCFPVCLWITK 184
L G S + + G IT LIPS++LP I K++ Q+ GR +G FP+ L +
Sbjct: 259 H-LHGYVSGEDVAGQHITDLIPSVQLPPSGQHIPKNLKIQRSVGRARDGTTFPLSLKLKS 317
Query: 185 PDNSDGAHWSAIKSQRSILEINLRVTYNVSGLLVVDEAGIITACNHHFAMLTFGKPHSEV 244
+S+ A + + S ++ V +SGL+ + G I NH FA+ FG +E+
Sbjct: 318 QPSSEEA-TTGEAAPVSGYRASVWVFCTISGLITLLPDGTIHGINHSFALTLFGYGKTEL 376
Query: 245 IGHHIDDVIQFFCRESDI-----VKLPDRA 269
+G +I +I F D+ ++LPD A
Sbjct: 377 LGKNITFLIPGFYSYMDLAYNSSLQLPDLA 406
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 148 bits (358), Expect = 1e-34
Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 14/259 (5%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y L+ +GKG YG VK A S RL+ + K I K+KI D D + E+ ++ +
Sbjct: 53 YEFLETLGKGTYGKVKKARESSGRLVAI-KSIRKDKIK-----DEQDLMHIRREIEIMSS 106
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP+I+++ +V+EN +VME G DL+++I R ++ E + FRQ+ AV Y
Sbjct: 107 LNHPHIIAIHEVFENSSKIVIVMEYASRG-DLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
H ++HR ++K+ DFG + + TF G+ Y SPE++ G
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKP 225
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWML 962
Y GPE++ WS+G+ LY+L PF ++ G P S D L+RW+L
Sbjct: 226 YTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS-DACGLIRWLL 284
Query: 963 CKDPANRCTITQLMSHPWI 981
+P R T+ + SH W+
Sbjct: 285 MVNPTRRATLEDVASHWWV 303
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 148 bits (358), Expect = 1e-34
Identities = 84/259 (32%), Positives = 131/259 (50%), Gaps = 14/259 (5%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y L+ +GKG YG VK A S RL+ + K I K+KI D D + E+ ++ +
Sbjct: 53 YEFLETLGKGTYGKVKKARESSGRLVAI-KSIRKDKIK-----DEQDLMHIRREIEIMSS 106
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP+I+++ +V+EN +VME G DL+++I R ++ E + FRQ+ AV Y
Sbjct: 107 LNHPHIIAIHEVFENSSKIVIVMEYASRG-DLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
H ++HR ++K+ DFG + + TF G+ Y SPE++ G
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKP 225
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWML 962
Y GPE++ WS+G+ LY+L PF ++ G P S D L+RW+L
Sbjct: 226 YTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPS-DACGLIRWLL 284
Query: 963 CKDPANRCTITQLMSHPWI 981
+P R T+ + SH W+
Sbjct: 285 MVNPTRRATLEDVASHWWV 303
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 147 bits (356), Expect = 2e-34
Identities = 87/277 (31%), Positives = 138/277 (49%), Gaps = 14/277 (5%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ + G Q A +Y Y K +GKG G VK+ K + +EK+
Sbjct: 1 MTSTGKDGGAQHA-QYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESV 59
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
L+ KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R
Sbjct: 60 LM------KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGR 112
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLF 889
+ FRQ+ A+++ HS +I HR ++++ DFG A+ DSL
Sbjct: 113 LTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLL 172
Query: 890 STFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGP 943
T G+ Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G
Sbjct: 173 ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV 232
Query: 944 LTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPW 980
PH + D + LLR M D A R T+ + H W
Sbjct: 233 FHMPHFIPPDCQSLLRGMSEVDAARRLTLEHIQKHIW 269
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 145 bits (351), Expect = 9e-34
Identities = 92/299 (30%), Positives = 145/299 (48%), Gaps = 16/299 (5%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E EK
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX 868
++ME + +G ++F+++ RM E FRQ+ AV+Y H I+HR
Sbjct: 130 LIME-YASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 869 XFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTF 928
++K+ DFG + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 189 DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 929 FVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E LL+ L +P R T+ Q+M WI
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 145 bits (351), Expect = 9e-34
Identities = 81/265 (30%), Positives = 130/265 (49%), Gaps = 13/265 (4%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+GKG + VK+ R + K I K ++ D + +K+ E+ ++ L HP+I
Sbjct: 26 LGKGNFAVVKLGRHRITKTEVAIKIIDKSQL------DAVNLEKIYREVQIMKMLDHPHI 79
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
+ L V E + +V E G ++F+++ R++E F Q+ AV+Y H I
Sbjct: 80 IKLYQVMETKSMLYLVTEYAKNG-EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 855 LHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPEL 914
+HR ++K+ DFG F L +T+ G+ Y +PEV G +Y GP+L
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 198
Query: 915 EMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPAN 968
++WSMG+ LYVL PF + ++G P+ +SED E L+R ML DP+
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 258
Query: 969 RCTITQLMSHPWIKQHVAIANYVFH 993
R TI Q+ H W+ V + V +
Sbjct: 259 RLTIAQIKEHKWMLIEVPVQRPVLY 283
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 145 bits (351), Expect = 9e-34
Identities = 81/265 (30%), Positives = 130/265 (49%), Gaps = 13/265 (4%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+GKG + VK+ R + K I K ++ D + +K+ E+ ++ L HP+I
Sbjct: 26 LGKGNFAVVKLGRHRITKTEVAIKIIDKSQL------DAVNLEKIYREVQIMKMLDHPHI 79
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
+ L V E + +V E G ++F+++ R++E F Q+ AV+Y H I
Sbjct: 80 IKLYQVMETKSMLYLVTEYAKNG-EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 138
Query: 855 LHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPEL 914
+HR ++K+ DFG F L +T+ G+ Y +PEV G +Y GP+L
Sbjct: 139 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 198
Query: 915 EMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPAN 968
++WSMG+ LYVL PF + ++G P+ +SED E L+R ML DP+
Sbjct: 199 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 258
Query: 969 RCTITQLMSHPWIKQHVAIANYVFH 993
R TI Q+ H W+ V + V +
Sbjct: 259 RLTIAQIKEHKWMLIEVPVQRPVLY 283
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 145 bits (351), Expect = 9e-34
Identities = 92/299 (30%), Positives = 145/299 (48%), Gaps = 16/299 (5%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E EK
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX 868
++ME + +G ++F+++ RM E FRQ+ AV+Y H I+HR
Sbjct: 130 LIME-YASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 869 XFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTF 928
++K+ DFG + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 189 DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 929 FVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E LL+ L +P R T+ Q+M WI
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 145 bits (351), Expect = 9e-34
Identities = 92/299 (30%), Positives = 145/299 (48%), Gaps = 16/299 (5%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E EK
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX 868
++ME + +G ++F+++ RM E FRQ+ AV+Y H I+HR
Sbjct: 130 LIME-YASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 869 XFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTF 928
++K+ DFG + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 189 DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 929 FVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E LL+ L +P R T+ Q+M WI
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 145 bits (351), Expect = 9e-34
Identities = 81/265 (30%), Positives = 130/265 (49%), Gaps = 13/265 (4%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+GKG + VK+ R + K I K ++ D + +K+ E+ ++ L HP+I
Sbjct: 24 LGKGNFAVVKLGRHRITKTEVAIKIIDKSQL------DAVNLEKIYREVQIMKMLDHPHI 77
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
+ L V E + +V E G ++F+++ R++E F Q+ AV+Y H I
Sbjct: 78 IKLYQVMETKSMLYLVTEYAKNG-EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 136
Query: 855 LHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPEL 914
+HR ++K+ DFG F L +T+ G+ Y +PEV G +Y GP+L
Sbjct: 137 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 196
Query: 915 EMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPAN 968
++WSMG+ LYVL PF + ++G P+ +SED E L+R ML DP+
Sbjct: 197 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 256
Query: 969 RCTITQLMSHPWIKQHVAIANYVFH 993
R TI Q+ H W+ V + V +
Sbjct: 257 RLTIAQIKEHKWMLIEVPVQRPVLY 281
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 145 bits (351), Expect = 9e-34
Identities = 81/265 (30%), Positives = 130/265 (49%), Gaps = 13/265 (4%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+GKG + VK+ R + K I K ++ D + +K+ E+ ++ L HP+I
Sbjct: 50 LGKGNFAVVKLGRHRITKTEVAIKIIDKSQL------DAVNLEKIYREVQIMKMLDHPHI 103
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
+ L V E + +V E G ++F+++ R++E F Q+ AV+Y H I
Sbjct: 104 IKLYQVMETKSMLYLVTEYAKNG-EIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKI 162
Query: 855 LHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPEL 914
+HR ++K+ DFG F L +T+ G+ Y +PEV G +Y GP+L
Sbjct: 163 VHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQL 222
Query: 915 EMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPAN 968
++WSMG+ LYVL PF + ++G P+ +SED E L+R ML DP+
Sbjct: 223 DIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK 282
Query: 969 RCTITQLMSHPWIKQHVAIANYVFH 993
R TI Q+ H W+ V + V +
Sbjct: 283 RLTIAQIKEHKWMLIEVPVQRPVLY 307
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 144 bits (350), Expect = 1e-33
Identities = 71/209 (33%), Positives = 114/209 (54%), Gaps = 7/209 (3%)
Query: 778 KVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSY 837
KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+
Sbjct: 14 KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARK 72
Query: 838 IFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTE 897
FRQ+ A+++ HS +I HR ++++ DFG A+ DSL T G+
Sbjct: 73 FFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPH 132
Query: 898 YCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVS 951
Y PEV+ G KY G +MWS G+ L+ L PF D +E +G PH +
Sbjct: 133 YACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIP 192
Query: 952 EDLEQLLRWMLCKDPANRCTITQLMSHPW 980
D + LLR M+ +P R ++ Q+ HPW
Sbjct: 193 PDCQSLLRGMIEVEPEKRLSLEQIQKHPW 221
>BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein.
Length = 326
Score = 144 bits (348), Expect = 2e-33
Identities = 85/262 (32%), Positives = 133/262 (50%), Gaps = 9/262 (3%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+ K Y +G G +G V R +D L K ++KE++ + G VPLE+
Sbjct: 36 FKKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGAT---VPLEVV 92
Query: 785 LLLTLKHPN----IVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFR 840
LL + ++ L+D +E F +V+E+ DLF+FI R +DEPL F
Sbjct: 93 LLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFA 152
Query: 841 QVGQAVEYLHSLNILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYC 899
QV AV + HS ++HR +KLIDFGS + KD++++ F GT Y
Sbjct: 153 QVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALL-KDTVYTDFDGTRVYS 211
Query: 900 SPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLR 959
PE + ++Y G +WS+G+ LY + PF E+ ++G L F VS + +QL+R
Sbjct: 212 PPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIR 271
Query: 960 WMLCKDPANRCTITQLMSHPWI 981
W L P+ R ++ Q+ +HPW+
Sbjct: 272 WCLSLRPSERPSLDQIAAHPWM 293
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 144 bits (348), Expect = 2e-33
Identities = 92/299 (30%), Positives = 144/299 (48%), Gaps = 16/299 (5%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E EK
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX 868
++ME + +G +F+++ RM E FRQ+ AV+Y H I+HR
Sbjct: 130 LIME-YASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 869 XFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTF 928
++K+ DFG + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 189 DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 929 FVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E LL+ L +P R T+ Q+M WI
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase
Pim-3 protein.
Length = 326
Score = 144 bits (348), Expect = 2e-33
Identities = 85/262 (32%), Positives = 133/262 (50%), Gaps = 9/262 (3%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+ K Y +G G +G V R +D L K ++KE++ + G VPLE+
Sbjct: 36 FEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGAT---VPLEVV 92
Query: 785 LLLTLKHPN----IVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFR 840
LL + ++ L+D +E F +V+E+ DLF+FI R +DEPL F
Sbjct: 93 LLRKVGAAGGARGVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFA 152
Query: 841 QVGQAVEYLHSLNILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYC 899
QV AV + HS ++HR +KLIDFGS + KD++++ F GT Y
Sbjct: 153 QVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALL-KDTVYTDFDGTRVYS 211
Query: 900 SPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLR 959
PE + ++Y G +WS+G+ LY + PF E+ ++G L F VS + +QL+R
Sbjct: 212 PPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIR 271
Query: 960 WMLCKDPANRCTITQLMSHPWI 981
W L P+ R ++ Q+ +HPW+
Sbjct: 272 WCLSLRPSERPSLDQIAAHPWM 293
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 143 bits (346), Expect = 4e-33
Identities = 90/286 (31%), Positives = 140/286 (48%), Gaps = 16/286 (5%)
Query: 705 SRPQSMSFVSQGGDEQVAGEYSKH---YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFIL 761
S+P S S + +G + + + H Y LK IGKG + VK+A K I
Sbjct: 26 SKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID 85
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLF 821
K ++ L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F
Sbjct: 86 KTQLNSSSL------QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVF 138
Query: 822 EFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSAT 881
+++ RM E FRQ+ AV+Y H I+HR ++K+ DFG +
Sbjct: 139 DYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSN 198
Query: 882 FMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------ 935
+ + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF
Sbjct: 199 EFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 258
Query: 936 IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
E ++G P +S D E LL+ L +P+ R T+ Q+M W+
Sbjct: 259 RERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 143 bits (346), Expect = 4e-33
Identities = 90/286 (31%), Positives = 140/286 (48%), Gaps = 16/286 (5%)
Query: 705 SRPQSMSFVSQGGDEQVAGEYSKH---YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFIL 761
S+P S S + +G + + + H Y LK IGKG + VK+A K I
Sbjct: 16 SKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID 75
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLF 821
K ++ L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F
Sbjct: 76 KTQLNSSSL------QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVF 128
Query: 822 EFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSAT 881
+++ RM E FRQ+ AV+Y H I+HR ++K+ DFG +
Sbjct: 129 DYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSN 188
Query: 882 FMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------ 935
+ + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF
Sbjct: 189 EFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 248
Query: 936 IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
E ++G P +S D E LL+ L +P+ R T+ Q+M W+
Sbjct: 249 RERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 294
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 143 bits (346), Expect = 4e-33
Identities = 90/286 (31%), Positives = 140/286 (48%), Gaps = 16/286 (5%)
Query: 705 SRPQSMSFVSQGGDEQVAGEYSKH---YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFIL 761
S+P S S + +G + + + H Y LK IGKG + VK+A K I
Sbjct: 26 SKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIID 85
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLF 821
K ++ L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F
Sbjct: 86 KTQLNSSSL------QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVME-YASGGEVF 138
Query: 822 EFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSAT 881
+++ RM E FRQ+ AV+Y H I+HR ++K+ DFG +
Sbjct: 139 DYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSN 198
Query: 882 FMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------ 935
+ + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF
Sbjct: 199 EFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKEL 258
Query: 936 IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
E ++G P +S D E LL+ L +P+ R T+ Q+M W+
Sbjct: 259 RERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWM 304
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 142 bits (345), Expect = 5e-33
Identities = 91/299 (30%), Positives = 144/299 (48%), Gaps = 16/299 (5%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E +K
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETQKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX 868
++ME + +G +F+++ RM E FRQ+ AV+Y H I+HR
Sbjct: 130 LIME-YASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDA 188
Query: 869 XFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTF 928
++K+ DFG + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 189 DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVS 248
Query: 929 FVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E LL+ L +P R T+ Q+M WI
Sbjct: 249 GSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWI 307
>DQ022562-1|AAY87461.1| 404|Homo sapiens pim-1 kinase 44 kDa
isoform protein.
Length = 404
Score = 142 bits (345), Expect = 5e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 135 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 192
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 193 GVIRLLDWFERPDSFVLILERXEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 252
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 253 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 311
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 312 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 371
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 372 FEEIQNHPWMQ 382
>M54915-1|AAA36447.1| 313|Homo sapiens pim-1 protein protein.
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>M27903-1|AAA60090.1| 313|Homo sapiens protein ( Human pim-1
proto-oncogene gene, complete cds. ).
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>M24779-1|AAA81553.1| 313|Homo sapiens protein kinase protein.
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>M16750-1|AAA60089.1| 313|Homo sapiens pim-1 protein protein.
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>BC020224-1|AAH20224.1| 313|Homo sapiens pim-1 oncogene protein.
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>AL353579-1|CAI20316.1| 313|Homo sapiens pim-1 oncogene protein.
Length = 313
Score = 142 bits (344), Expect = 6e-33
Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 6/251 (2%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKH--P 792
+G G +G V R SD L K + K++I + P+G +VP+E+ LL +
Sbjct: 44 LGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGEL--PNGTRVPMEVVLLKKVSSGFS 101
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
++ L+D +E F +++E+ DLF+FI R + E L F QV +AV + H+
Sbjct: 102 GVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNC 161
Query: 853 NILHRXXXXXXXXXXXXF-HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+LHR +KLIDFGS + KD++++ F GT Y PE + ++Y G
Sbjct: 162 GVLHRDIKDENILIDLNRGELKLIDFGSGALL-KDTVYTDFDGTRVYSPPEWIRYHRYHG 220
Query: 912 PELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCT 971
+WS+GI LY + PF E+ I+G + F VS + + L+RW L P++R T
Sbjct: 221 RSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPT 280
Query: 972 ITQLMSHPWIK 982
++ +HPW++
Sbjct: 281 FEEIQNHPWMQ 291
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 140 bits (338), Expect = 3e-32
Identities = 81/256 (31%), Positives = 125/256 (48%), Gaps = 13/256 (5%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+ +GKG + VK+A R + K I K ++ D + +K+ E+ L+ L HP
Sbjct: 31 RTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL------DSSNLEKIYREVQLMKLLNHP 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
+I+ L V E + +V E G ++F+++ + E F Q+ AVEY H
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNG-EMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 853 NILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGP 912
+I+HR +KL DFG F ST+ G+ Y +PEV G +Y GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203
Query: 913 ELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDP 966
+L++WS+G+ LYVL PF + ++G P +S+D E L+R ML DP
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263
Query: 967 ANRCTITQLMSHPWIK 982
A R TI Q+ H W++
Sbjct: 264 ARRITIAQIRQHRWMR 279
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 140 bits (338), Expect = 3e-32
Identities = 81/256 (31%), Positives = 125/256 (48%), Gaps = 13/256 (5%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+ +GKG + VK+A R + K I K ++ D + +K+ E+ L+ L HP
Sbjct: 12 RTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL------DSSNLEKIYREVQLMKLLNHP 65
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
+I+ L V E + +V E G ++F+++ + E F Q+ AVEY H
Sbjct: 66 HIIKLYQVMETKDMLYIVTEFAKNG-EMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 124
Query: 853 NILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGP 912
+I+HR +KL DFG F ST+ G+ Y +PEV G +Y GP
Sbjct: 125 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 184
Query: 913 ELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDP 966
+L++WS+G+ LYVL PF + ++G P +S+D E L+R ML DP
Sbjct: 185 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 244
Query: 967 ANRCTITQLMSHPWIK 982
A R TI Q+ H W++
Sbjct: 245 ARRITIAQIRQHRWMR 260
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 140 bits (338), Expect = 3e-32
Identities = 81/256 (31%), Positives = 125/256 (48%), Gaps = 13/256 (5%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+ +GKG + VK+A R + K I K ++ D + +K+ E+ L+ L HP
Sbjct: 31 RTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL------DSSNLEKIYREVQLMKLLNHP 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
+I+ L V E + +V E G ++F+++ + E F Q+ AVEY H
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNG-EMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 853 NILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGP 912
+I+HR +KL DFG F ST+ G+ Y +PEV G +Y GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203
Query: 913 ELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDP 966
+L++WS+G+ LYVL PF + ++G P +S+D E L+R ML DP
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263
Query: 967 ANRCTITQLMSHPWIK 982
A R TI Q+ H W++
Sbjct: 264 ARRITIAQIRQHRWMR 279
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 139 bits (337), Expect = 4e-32
Identities = 87/281 (30%), Positives = 138/281 (49%), Gaps = 16/281 (5%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 41 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 97
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F+++
Sbjct: 98 PTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVA 150
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 210
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 211 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 270
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 271 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 139 bits (337), Expect = 4e-32
Identities = 87/281 (30%), Positives = 138/281 (49%), Gaps = 16/281 (5%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 41 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 97
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F+++
Sbjct: 98 PTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVA 150
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 210
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 211 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 270
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 271 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 139 bits (337), Expect = 4e-32
Identities = 87/281 (30%), Positives = 138/281 (49%), Gaps = 16/281 (5%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 41 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 97
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F+++
Sbjct: 98 PTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVA 150
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 210
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 211 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 270
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 271 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 139 bits (337), Expect = 4e-32
Identities = 87/281 (30%), Positives = 138/281 (49%), Gaps = 16/281 (5%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 41 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 97
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNIV L +V E EK +VME + +G ++F+++
Sbjct: 98 PTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVA 150
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 151 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 210
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 211 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 270
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 271 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 311
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 139 bits (336), Expect = 6e-32
Identities = 86/273 (31%), Positives = 135/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G VK+ + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQ--GLPSYLFPE 279
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 139 bits (336), Expect = 6e-32
Identities = 86/273 (31%), Positives = 135/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G VK+ + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQD--LPSYLFPE 279
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 139 bits (336), Expect = 6e-32
Identities = 86/273 (31%), Positives = 135/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G VK+ + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQD--LPSYLFPE 279
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 139 bits (336), Expect = 6e-32
Identities = 86/273 (31%), Positives = 135/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G VK+ + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQD--LPSYLFPE 279
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 139 bits (336), Expect = 6e-32
Identities = 86/273 (31%), Positives = 135/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G VK+ + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQD--LPSYLFPE 279
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 138 bits (334), Expect = 1e-31
Identities = 70/209 (33%), Positives = 113/209 (54%), Gaps = 7/209 (3%)
Query: 778 KVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSY 837
KV E+++L ++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+
Sbjct: 108 KVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARK 166
Query: 838 IFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTE 897
FRQ+ A+++ HS +I HR ++++ DFG A+ DSL T G+
Sbjct: 167 FFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPH 226
Query: 898 YCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVS 951
Y PEV+ G KY G + ++WS G+ L+ L PF D +E +G PH +
Sbjct: 227 YACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIP 286
Query: 952 EDLEQLLRWMLCKDPANRCTITQLMSHPW 980
D + LLR M+ D A R T+ + H W
Sbjct: 287 PDCQSLLRGMIEVDAARRLTLEHIQKHIW 315
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 138 bits (333), Expect = 1e-31
Identities = 84/260 (32%), Positives = 129/260 (49%), Gaps = 13/260 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y LK IGKG + VK+A K I K ++ L +K+ E+ ++
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL------QKLFREVRIMK 72
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
L HPNIV L +V E EK +VME + +G ++F+++ RM E FRQ+ AV+
Sbjct: 73 VLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 131
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H I+HR ++K+ DFG + + + TF G+ Y +PE+ G
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK 191
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
KY GPE+++WS+G+ LY L PF E ++G P +S D E LL+
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 251
Query: 962 LCKDPANRCTITQLMSHPWI 981
L +P+ R T+ Q+M W+
Sbjct: 252 LILNPSKRGTLEQIMKDRWM 271
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 138 bits (333), Expect = 1e-31
Identities = 84/260 (32%), Positives = 129/260 (49%), Gaps = 13/260 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y LK IGKG + VK+A K I K ++ L +K+ E+ ++
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL------QKLFREVRIMK 72
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
L HPNIV L +V E EK +VME + +G ++F+++ RM E FRQ+ AV+
Sbjct: 73 VLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 131
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H I+HR ++K+ DFG + + + TF G+ Y +PE+ G
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK 191
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
KY GPE+++WS+G+ LY L PF E ++G P +S D E LL+
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 251
Query: 962 LCKDPANRCTITQLMSHPWI 981
L +P+ R T+ Q+M W+
Sbjct: 252 LILNPSKRGTLEQIMKDRWM 271
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 138 bits (333), Expect = 1e-31
Identities = 84/260 (32%), Positives = 129/260 (49%), Gaps = 13/260 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y LK IGKG + VK+A K I K ++ L +K+ E+ ++
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL------QKLFREVRIMK 72
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
L HPNIV L +V E EK +VME + +G ++F+++ RM E FRQ+ AV+
Sbjct: 73 VLNHPNIVKLFEVIETEKTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQ 131
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H I+HR ++K+ DFG + + + TF G+ Y +PE+ G
Sbjct: 132 YCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGK 191
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
KY GPE+++WS+G+ LY L PF E ++G P +S D E LL+
Sbjct: 192 KYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKF 251
Query: 962 LCKDPANRCTITQLMSHPWI 981
L +P+ R T+ Q+M W+
Sbjct: 252 LILNPSKRGTLEQIMKDRWM 271
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 137 bits (331), Expect = 2e-31
Identities = 85/273 (31%), Positives = 134/273 (49%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HYV +G G +G V + + K + ++KI L +V K+ E+ L
Sbjct: 15 HYVLGDTLGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVG-----KIKREIQNLK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V F MVME + +G +LF++I + R++E +F+Q+ AV+
Sbjct: 70 LFRHPHIIKLYQVISTPTDFFMVME-YVSGGELFDYICKHGRVEEMEARRLFQQILSAVD 128
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 129 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 188
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQGPLTF-PHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + I+G + + P ++ + LL M
Sbjct: 189 LYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHM 248
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + +Y+F E
Sbjct: 249 LQVDPLKRATIKDIREHEWFKQD--LPSYLFPE 279
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 136 bits (328), Expect = 6e-31
Identities = 82/269 (30%), Positives = 136/269 (50%), Gaps = 13/269 (4%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y + IGKG + VK R+ L+T K +K I +D + KK+ E+ ++
Sbjct: 7 YYEIDRTIGKGNFAVVK----RATHLVTKAKVAIK--IIDKTQLDEENLKKIFREVQIMK 60
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
L HP+I+ L V E E+ +V E + +G ++F+ + RM E F+Q+ AV
Sbjct: 61 MLCHPHIIRLYQVMETERMIYLVTE-YASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVY 119
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
+ H NI+HR ++K+ DFG + + L T+ G+ Y +PE+ G
Sbjct: 120 FCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGK 179
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPF--SDIED----TIQGPLTFPHLVSEDLEQLLRWM 961
+Y GP++++WS+G+ LYVL PF S +++ + G P +S + E L+R M
Sbjct: 180 EYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHM 239
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANY 990
L DP R ++ Q+ H W+K A N+
Sbjct: 240 LVLDPNKRLSMEQICKHKWMKLGDADPNF 268
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 136 bits (328), Expect = 6e-31
Identities = 82/269 (30%), Positives = 136/269 (50%), Gaps = 13/269 (4%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y + IGKG + VK R+ L+T K +K I +D + KK+ E+ ++
Sbjct: 115 YYEIDRTIGKGNFAVVK----RATHLVTKAKVAIK--IIDKTQLDEENLKKIFREVQIMK 168
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
L HP+I+ L V E E+ +V E + +G ++F+ + RM E F+Q+ AV
Sbjct: 169 MLCHPHIIRLYQVMETERMIYLVTE-YASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVY 227
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
+ H NI+HR ++K+ DFG + + L T+ G+ Y +PE+ G
Sbjct: 228 FCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGK 287
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPF--SDIED----TIQGPLTFPHLVSEDLEQLLRWM 961
+Y GP++++WS+G+ LYVL PF S +++ + G P +S + E L+R M
Sbjct: 288 EYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHM 347
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANY 990
L DP R ++ Q+ H W+K A N+
Sbjct: 348 LVLDPNKRLSMEQICKHKWMKLGDADPNF 376
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 135 bits (327), Expect = 7e-31
Identities = 83/273 (30%), Positives = 128/273 (46%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY+ +G G +G VK+ K + ++KI L +V K+ E+ L
Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVG-----KIRREIQNLK 71
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V MVME + +G +LF++I + R+DE +F+Q+ V+
Sbjct: 72 LFRHPHIIKLYQVISTPSDIFMVME-YVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 130
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 131 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 190
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + G P ++ + LL+ M
Sbjct: 191 LYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHM 250
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R TI + H W KQ + Y+F E
Sbjct: 251 LQVDPMKRATIKDIREHEWFKQD--LPKYLFPE 281
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 134 bits (325), Expect = 1e-30
Identities = 117/392 (29%), Positives = 183/392 (46%), Gaps = 43/392 (10%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 167 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 226
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 227 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 284
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 285 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 344
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 345 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 404
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 405 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 462
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 463 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 522
Query: 1052 KRSSVALHALSTADRDAHSDNYSLRSSADILD 1083
R +L L + D+ + +A LD
Sbjct: 523 TRECESLSELKGTKKKKGLDSMTSTVAAGWLD 554
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 134 bits (324), Expect = 2e-30
Identities = 114/372 (30%), Positives = 176/372 (47%), Gaps = 43/372 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 521
Query: 1052 KRSSVALHALST 1063
R +L L T
Sbjct: 522 TRECESLSELKT 533
>AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-dependent
protein kinase kinase b2 protein.
Length = 533
Score = 134 bits (324), Expect = 2e-30
Identities = 114/372 (30%), Positives = 176/372 (47%), Gaps = 43/372 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 521
Query: 1052 KRSSVALHALST 1063
R +L L T
Sbjct: 522 TRECESLSELKT 533
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 134 bits (324), Expect = 2e-30
Identities = 114/372 (30%), Positives = 176/372 (47%), Gaps = 43/372 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 50 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 109
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 110 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 167
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 168 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 227
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 228 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 287
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 288 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 345
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 346 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 405
Query: 1052 KRSSVALHALST 1063
R +L L T
Sbjct: 406 TRECESLSELKT 417
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 134 bits (323), Expect = 2e-30
Identities = 81/259 (31%), Positives = 125/259 (48%), Gaps = 16/259 (6%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+ +GKG + VK+A R + K I K ++ D + +K+ E+ L+ L HP
Sbjct: 31 RTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRL------DSSNLEKIYREVQLMKLLNHP 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
+I+ L V E + +V E G ++F+++ + E F Q+ AVEY H
Sbjct: 85 HIIKLYQVMETKDMLYIVTEFAKNG-EMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143
Query: 853 NILHRXXXXXXXXXXXXFHVKLI---DFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKY 909
+I+HR +KL DFG F ST+ G+ Y +PEV G +Y
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLAGTEDFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEY 203
Query: 910 AGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLC 963
GP+L++WS+G+ LYVL PF + ++G P +S+D E L+R ML
Sbjct: 204 EGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLV 263
Query: 964 KDPANRCTITQLMSHPWIK 982
DPA R TI Q+ H W++
Sbjct: 264 VDPARRITIAQIRQHRWMR 282
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 134 bits (323), Expect = 2e-30
Identities = 82/273 (30%), Positives = 128/273 (46%), Gaps = 14/273 (5%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY+ +G G +G VK+ K + ++KI L +V K+ E+ L
Sbjct: 17 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVG-----KIRREIQNLK 71
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
+HP+I+ L V MVME + +G +LF++I + R+DE +F+Q+ V+
Sbjct: 72 LFRHPHIIKLYQVISTPSDIFMVME-YVSGGELFDYICKNGRLDEKESRRLFQQILSGVD 130
Query: 848 YLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGN 907
Y H ++HR + K+ DFG + MS T G+ Y +PEV++G
Sbjct: 131 YCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGR 190
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
YAGPE+++WS G+ LY L PF D + G P ++ + LL+ M
Sbjct: 191 LYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHM 250
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
L DP R +I + H W KQ + Y+F E
Sbjct: 251 LQVDPMKRASIKDIREHEWFKQD--LPKYLFPE 281
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 133 bits (322), Expect = 3e-30
Identities = 114/373 (30%), Positives = 176/373 (47%), Gaps = 43/373 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 521
Query: 1052 KRSSVALHALSTA 1064
R +L L A
Sbjct: 522 TRECESLSELKEA 534
>AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-dependent
protein kinase kinase b1 protein.
Length = 588
Score = 133 bits (322), Expect = 3e-30
Identities = 114/373 (30%), Positives = 176/373 (47%), Gaps = 43/373 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 521
Query: 1052 KRSSVALHALSTA 1064
R +L L A
Sbjct: 522 TRECESLSELKEA 534
>BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-dependent
protein kinase kinase 2, beta protein.
Length = 541
Score = 133 bits (321), Expect = 4e-30
Identities = 110/351 (31%), Positives = 170/351 (48%), Gaps = 39/351 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
E E N S + V V + ++RS NP E R EE+++S
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFE-GSRREERSLS 511
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 133 bits (321), Expect = 4e-30
Identities = 110/351 (31%), Positives = 170/351 (48%), Gaps = 39/351 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
E E N S + V V + ++RS NP E R EE+++S
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFE-GSRREERSLS 511
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 133 bits (321), Expect = 4e-30
Identities = 113/373 (30%), Positives = 176/373 (47%), Gaps = 43/373 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAAFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S + GT + +PE L+ + ++G ++W+MG+TLY F PF D + I+
Sbjct: 344 LSNYVGTPAFMAPESLSETRKIFSGKAKDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEK-----NVSREEP 1051
E E N S + V V + ++RS NP E + R E N+ ++P
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKKP 521
Query: 1052 KRSSVALHALSTA 1064
R +L L A
Sbjct: 522 TRECESLSELKEA 534
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 133 bits (321), Expect = 4e-30
Identities = 110/351 (31%), Positives = 170/351 (48%), Gaps = 39/351 (11%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 GP-LTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIIDC 998
L FP ++EDL+ L+ ML K+P +R + ++ HPW+ +H A + E +C
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHG--AEPLPSEDENC 461
Query: 999 DRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
E E N S + V V + ++RS NP E R EE+++S
Sbjct: 462 TLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFE-GSRREERSLS 511
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 130 bits (313), Expect = 4e-29
Identities = 66/198 (33%), Positives = 105/198 (53%), Gaps = 7/198 (3%)
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
++HP+++ L DVYEN+KY +V+E H +G +LF+++ ++ R+ FRQ+ A+++
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLE-HVSGGELFDYLVKKGRLTPKEARKFFRQIISALDF 60
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
HS +I HR ++++ DFG A+ DSL T G+ Y PEV+ G K
Sbjct: 61 CHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEK 120
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWML 962
Y G + ++WS G+ L+ L PF D +E +G PH + D + LLR M
Sbjct: 121 YDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMS 180
Query: 963 CKDPANRCTITQLMSHPW 980
D A R T+ + H W
Sbjct: 181 EVDAARRLTLEHIQKHIW 198
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 125 bits (301), Expect = 1e-27
Identities = 92/322 (28%), Positives = 147/322 (45%), Gaps = 39/322 (12%)
Query: 689 TSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYR 748
TS D + ++++ S + + ++ DEQ + +Y LK IGKG + VK+A
Sbjct: 19 TSHGDGRQEVTSRTSRSGARCRNSIASCADEQ---PHIGNYRLLKTIGKGNFAKVKLARH 75
Query: 749 RSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQ 808
K I K ++ P L +K+ E+ ++ L HPNIV L +V E EK
Sbjct: 76 ILTGREVAIKIIDKTQLNPTSL------QKLFREVRIMKILNHPNIVKLFEVIETEKTLY 129
Query: 809 MVMEKHGAGMDLFEFIERRPRMDEP-----------------------LLSYIFRQVGQA 845
++ME + +G ++F+++ +M E LLS +F + A
Sbjct: 130 LIME-YASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSA 188
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
V+Y H I+HR ++K+ DFG + + TF G+ Y +PE+
Sbjct: 189 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQ 248
Query: 906 GNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLR 959
G KY GPE+++WS+G+ LY L PF E ++G P +S D E LL+
Sbjct: 249 GKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK 308
Query: 960 WMLCKDPANRCTITQLMSHPWI 981
L +P R T+ Q+M WI
Sbjct: 309 RFLVLNPIKRGTLEQIMKDRWI 330
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 123 bits (297), Expect = 3e-27
Identities = 85/268 (31%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
E K+Y + IG G + VK+A + K + K +G D ++ E+
Sbjct: 11 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-------DLPRIKTEI 63
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
L L+H +I L V E MV+E + G +LF++I + R+ E +FRQ+
Sbjct: 64 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 122
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFM--SKDSLFSTFYGTTEYCSP 901
AV Y+HS HR +KLIDFG +KD T G+ Y +P
Sbjct: 123 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 182
Query: 902 EVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLE 955
E++ G Y G E ++WSMGI LYVL PF D + ++G P +S
Sbjct: 183 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 242
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWIKQ 983
LL+ ML DP R ++ L++HPWI Q
Sbjct: 243 LLLQQMLQVDPKKRISMKNLLNHPWIMQ 270
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 123 bits (297), Expect = 3e-27
Identities = 85/268 (31%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
E K+Y + IG G + VK+A + K + K +G D ++ E+
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-------DLPRIKTEI 58
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
L L+H +I L V E MV+E + G +LF++I + R+ E +FRQ+
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFM--SKDSLFSTFYGTTEYCSP 901
AV Y+HS HR +KLIDFG +KD T G+ Y +P
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 902 EVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLE 955
E++ G Y G E ++WSMGI LYVL PF D + ++G P +S
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 237
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWIKQ 983
LL+ ML DP R ++ L++HPWI Q
Sbjct: 238 LLLQQMLQVDPKKRISMKNLLNHPWIMQ 265
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 123 bits (297), Expect = 3e-27
Identities = 85/268 (31%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
E K+Y + IG G + VK+A + K + K +G D ++ E+
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-------DLPRIKTEI 58
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
L L+H +I L V E MV+E + G +LF++I + R+ E +FRQ+
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFM--SKDSLFSTFYGTTEYCSP 901
AV Y+HS HR +KLIDFG +KD T G+ Y +P
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 902 EVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLE 955
E++ G Y G E ++WSMGI LYVL PF D + ++G P +S
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 237
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWIKQ 983
LL+ ML DP R ++ L++HPWI Q
Sbjct: 238 LLLQQMLQVDPKKRISMKNLLNHPWIMQ 265
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 123 bits (297), Expect = 3e-27
Identities = 85/268 (31%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
E K+Y + IG G + VK+A + K + K +G D ++ E+
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-------DLPRIKTEI 58
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
L L+H +I L V E MV+E + G +LF++I + R+ E +FRQ+
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFM--SKDSLFSTFYGTTEYCSP 901
AV Y+HS HR +KLIDFG +KD T G+ Y +P
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 902 EVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLE 955
E++ G Y G E ++WSMGI LYVL PF D + ++G P +S
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 237
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWIKQ 983
LL+ ML DP R ++ L++HPWI Q
Sbjct: 238 LLLQQMLQVDPKKRISMKNLLNHPWIMQ 265
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 123 bits (297), Expect = 3e-27
Identities = 85/268 (31%), Positives = 124/268 (46%), Gaps = 16/268 (5%)
Query: 724 EYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLEL 783
E K+Y + IG G + VK+A + K + K +G D ++ E+
Sbjct: 6 ELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGS-------DLPRIKTEI 58
Query: 784 SLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVG 843
L L+H +I L V E MV+E + G +LF++I + R+ E +FRQ+
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLE-YCPGGELFDYIISQDRLSEEETRVVFRQIV 117
Query: 844 QAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFM--SKDSLFSTFYGTTEYCSP 901
AV Y+HS HR +KLIDFG +KD T G+ Y +P
Sbjct: 118 SAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAP 177
Query: 902 EVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLE 955
E++ G Y G E ++WSMGI LYVL PF D + ++G P +S
Sbjct: 178 ELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSI 237
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWIKQ 983
LL+ ML DP R ++ L++HPWI Q
Sbjct: 238 LLLQQMLQVDPKKRISMKNLLNHPWIMQ 265
>U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homolog
pim-2h protein.
Length = 334
Score = 120 bits (289), Expect = 3e-26
Identities = 79/272 (29%), Positives = 134/272 (49%), Gaps = 10/272 (3%)
Query: 716 GGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPD 775
GG ++ A + Y +GKG +G V +R +DRL K I + ++ L D
Sbjct: 21 GGKDREA--FEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRV--LGWSPLSD 76
Query: 776 GKKVPLELSLLLTLK----HPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMD 831
PLE++LL + HP ++ L+D +E ++ F +V+E+ DLF++I + +
Sbjct: 77 SVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLG 136
Query: 832 EPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKDSLFS 890
E F QV A+++ HS ++HR KLIDFGS + D ++
Sbjct: 137 EGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYT 195
Query: 891 TFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLV 950
F GT Y PE ++ ++Y +WS+GI LY + PF ++ ++ L FP V
Sbjct: 196 DFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHV 255
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
S D L+R L P++R ++ +++ PW++
Sbjct: 256 SPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ 287
>BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein.
Length = 311
Score = 120 bits (289), Expect = 3e-26
Identities = 79/272 (29%), Positives = 134/272 (49%), Gaps = 10/272 (3%)
Query: 716 GGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPD 775
GG ++ A + Y +GKG +G V +R +DRL K I + ++ L D
Sbjct: 21 GGKDREA--FEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRV--LGWSPLSD 76
Query: 776 GKKVPLELSLLLTLK----HPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMD 831
PLE++LL + HP ++ L+D +E ++ F +V+E+ DLF++I + +
Sbjct: 77 SVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLG 136
Query: 832 EPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKDSLFS 890
E F QV A+++ HS ++HR KLIDFGS + D ++
Sbjct: 137 EGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYT 195
Query: 891 TFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLV 950
F GT Y PE ++ ++Y +WS+GI LY + PF ++ ++ L FP V
Sbjct: 196 DFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHV 255
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
S D L+R L P++R ++ +++ PW++
Sbjct: 256 SPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ 287
>AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene
homolog protein.
Length = 311
Score = 120 bits (289), Expect = 3e-26
Identities = 79/272 (29%), Positives = 134/272 (49%), Gaps = 10/272 (3%)
Query: 716 GGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPD 775
GG ++ A + Y +GKG +G V +R +DRL K I + ++ L D
Sbjct: 21 GGKDREA--FEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRV--LGWSPLSD 76
Query: 776 GKKVPLELSLLLTLK----HPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMD 831
PLE++LL + HP ++ L+D +E ++ F +V+E+ DLF++I + +
Sbjct: 77 SVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLG 136
Query: 832 EPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKDSLFS 890
E F QV A+++ HS ++HR KLIDFGS + D ++
Sbjct: 137 EGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLH-DEPYT 195
Query: 891 TFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLV 950
F GT Y PE ++ ++Y +WS+GI LY + PF ++ ++ L FP V
Sbjct: 196 DFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHV 255
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
S D L+R L P++R ++ +++ PW++
Sbjct: 256 SPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ 287
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 120 bits (288), Expect = 4e-26
Identities = 79/282 (28%), Positives = 138/282 (48%), Gaps = 19/282 (6%)
Query: 709 SMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPL 768
SM+ +G D ++AG Y K +G+G + VK+A K I K K+ L
Sbjct: 1 SMAGFKRGYDGKIAGLYDLD----KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL 56
Query: 769 FLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRP 828
G E+ + ++HPNIV L +V + + +++E G G D+F++I +
Sbjct: 57 -----ATGHLFQ-EVRCMKLVQHPNIVRLYEVIDTQTKLYLILEL-GDGGDMFDYIMKHE 109
Query: 829 R-MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKD 886
++E L F Q+ A+ Y H L+++HR VKL DFG +
Sbjct: 110 EGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPG 169
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDT------I 940
+T G+ Y +PE+L G++Y P +++WS+G+ L++L PF + D+ +
Sbjct: 170 KKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIM 229
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
T P VS++ + L+ ML +DP R ++ ++ +HPW++
Sbjct: 230 DCKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQ 271
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 120 bits (288), Expect = 4e-26
Identities = 83/288 (28%), Positives = 128/288 (44%), Gaps = 29/288 (10%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY+ +G G +G VK+ K + ++KI L +V K+ E+ L
Sbjct: 26 HYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVG-----KIRREIQNLK 80
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR---------------MDE 832
+HP+I+ L V MVME + +G +LF++I + R +DE
Sbjct: 81 LFRHPHIIKLYQVISTPSDIFMVME-YVSGGELFDYICKNGRKSDVPGVVKTGSTKELDE 139
Query: 833 PLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF 892
+F+Q+ V+Y H ++HR + K+ DFG + MS T
Sbjct: 140 KESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 199
Query: 893 YGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF 946
G+ Y +PEV++G YAGPE+++WS G+ LY L PF D + G
Sbjct: 200 CGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYT 259
Query: 947 PHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHE 994
P ++ + LL+ ML DP R TI + H W KQ + Y+F E
Sbjct: 260 PQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQD--LPKYLFPE 305
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 117 bits (281), Expect = 3e-25
Identities = 78/281 (27%), Positives = 136/281 (48%), Gaps = 19/281 (6%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ +G D ++AG Y K +G+G + VK+A K I K K+ L
Sbjct: 1 MAGFKRGYDGKIAGLYDLD----KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL- 55
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
G E+ + ++HPNIV L +V + + +++E G G D+F++I +
Sbjct: 56 ----ATGHLFQ-EVRCMKLVQHPNIVRLYEVIDTQTKLYLILEL-GDGGDMFDYIMKHEE 109
Query: 830 -MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKDS 887
++E L F Q+ A+ Y H L+++HR VKL DFG +
Sbjct: 110 GLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGK 169
Query: 888 LFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDT------IQ 941
+T G+ Y +PE+L G++Y P +++WS+G+ L++L PF + D+ +
Sbjct: 170 KLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD 229
Query: 942 GPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
T P VS++ + L+ ML +DP R + ++ +HPW++
Sbjct: 230 CKYTVPSHVSKECKDLITRMLQRDPKRRAYLEEIENHPWLQ 270
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 12 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 70 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 245
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 246 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 276
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 117 bits (281), Expect = 3e-25
Identities = 81/271 (29%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
+Y T +++G G + VK +S L KFI K + G + + E+S+L
Sbjct: 15 YYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRR--GVSREDIEREVSILK 72
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPN+++L +VYEN+ +++E AG +LF+F+ + + E + +Q+ V
Sbjct: 73 EIQHPNVITLHEVYENKTDVILILEL-VAGGELFDFLAEKESLTEEEATEFLKQILNGVY 131
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHSL I H +K+IDFG A + + F +GT E+ +PE+
Sbjct: 132 YLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEI 191
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLE-------- 955
+ + G E +MWS+G+ Y+L PF + DT Q L V+ + E
Sbjct: 192 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANVSAVNYEFEDEYFSNTS 248
Query: 956 ----QLLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI + HPWIK
Sbjct: 249 ALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK 279
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 116 bits (279), Expect = 5e-25
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 20/270 (7%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRL-LTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
K Y+ +GKG+Y VK AY S+RL V I+ K P V+ + +P E+ +
Sbjct: 10 KGYIVGINLGKGSYAKVKSAY--SERLKFNVAVKIIDRKKTPTDFVE----RFLPREMDI 63
Query: 786 LLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQA 845
L T+ H +I+ +++E ++ + G DL EFI+ + + E + +FRQ+ A
Sbjct: 64 LATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSA 123
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDS-----LFSTFYGTTEYCS 900
V+Y H L+I+HR F++KL DFG + +DS L TF G+ Y +
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI----QGPLTFPHL--VSE 952
PEVL Y ++WS+G+ LY++ P+ SDI + + + FP ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
+ + L+ ML D + R I +++SH W++
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 116 bits (279), Expect = 5e-25
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 20/270 (7%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRL-LTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
K Y+ +GKG+Y VK AY S+RL V I+ K P V+ + +P E+ +
Sbjct: 10 KGYIVGINLGKGSYAKVKSAY--SERLKFNVAVKIIDRKKTPTDFVE----RFLPREMDI 63
Query: 786 LLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQA 845
L T+ H +I+ +++E ++ + G DL EFI+ + + E + +FRQ+ A
Sbjct: 64 LATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSA 123
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDS-----LFSTFYGTTEYCS 900
V+Y H L+I+HR F++KL DFG + +DS L TF G+ Y +
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI----QGPLTFPHL--VSE 952
PEVL Y ++WS+G+ LY++ P+ SDI + + + FP ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
+ + L+ ML D + R I +++SH W++
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 116 bits (279), Expect = 5e-25
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 20/270 (7%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRL-LTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
K Y+ +GKG+Y VK AY S+RL V I+ K P V+ + +P E+ +
Sbjct: 10 KGYIVGINLGKGSYAKVKSAY--SERLKFNVAVKIIDRKKTPTDFVE----RFLPREMDI 63
Query: 786 LLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQA 845
L T+ H +I+ +++E ++ + G DL EFI+ + + E + +FRQ+ A
Sbjct: 64 LATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSA 123
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDS-----LFSTFYGTTEYCS 900
V+Y H L+I+HR F++KL DFG + +DS L TF G+ Y +
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI----QGPLTFPHL--VSE 952
PEVL Y ++WS+G+ LY++ P+ SDI + + + FP ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
+ + L+ ML D + R I +++SH W++
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 116 bits (279), Expect = 5e-25
Identities = 81/270 (30%), Positives = 136/270 (50%), Gaps = 20/270 (7%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRL-LTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
K Y+ +GKG+Y VK AY S+RL V I+ K P V+ + +P E+ +
Sbjct: 10 KGYIVGINLGKGSYAKVKSAY--SERLKFNVAVKIIDRKKTPTDFVE----RFLPREMDI 63
Query: 786 LLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQA 845
L T+ H +I+ +++E ++ + G DL EFI+ + + E + +FRQ+ A
Sbjct: 64 LATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSA 123
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDS-----LFSTFYGTTEYCS 900
V+Y H L+I+HR F++KL DFG + +DS L TF G+ Y +
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI----QGPLTFPHL--VSE 952
PEVL Y ++WS+G+ LY++ P+ SDI + + + FP ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
+ + L+ ML D + R I +++SH W++
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQ 273
>AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 498
Score = 116 bits (278), Expect = 6e-25
Identities = 88/277 (31%), Positives = 137/277 (49%), Gaps = 34/277 (12%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 G-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQL 975
L FP ++EDL+ L+ ML K+P +R + ++
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEI 440
>AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 545
Score = 116 bits (278), Expect = 6e-25
Identities = 88/277 (31%), Positives = 137/277 (49%), Gaps = 34/277 (12%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 G-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQL 975
L FP ++EDL+ L+ ML K+P +R + ++
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEI 440
>AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform
protein.
Length = 490
Score = 116 bits (278), Expect = 6e-25
Identities = 88/277 (31%), Positives = 137/277 (49%), Gaps = 34/277 (12%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 G-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQL 975
L FP ++EDL+ L+ ML K+P +R + ++
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEI 440
>AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3x protein.
Length = 498
Score = 116 bits (278), Expect = 6e-25
Identities = 88/277 (31%), Positives = 137/277 (49%), Gaps = 34/277 (12%)
Query: 731 TLK-QIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI----------GPLFLVDGPDG--- 776
TLK +IGKG+YG VK+AY +D K + K+K+ P P G
Sbjct: 166 TLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQ 225
Query: 777 -----KKVPLELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPR 829
++V E+++L L HPN+V LV+V + NE + MV E G + E +P
Sbjct: 226 PRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP- 283
Query: 830 MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSL 888
+ E + F+ + + +EYLH I+HR H+K+ DFG S F D+L
Sbjct: 284 LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDAL 343
Query: 889 FSTFYGTTEYCSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQ 941
S GT + +PE L+ + ++G L++W+MG+TLY F PF D + I+
Sbjct: 344 LSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIK 403
Query: 942 G-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQL 975
L FP ++EDL+ L+ ML K+P +R + ++
Sbjct: 404 SQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEI 440
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 115 bits (277), Expect = 8e-25
Identities = 77/281 (27%), Positives = 136/281 (48%), Gaps = 19/281 (6%)
Query: 710 MSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLF 769
M+ +G D ++AG Y K +G+G + VK+A K I K K+ L
Sbjct: 1 MAGFKRGYDGKIAGLYDLD----KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTL- 55
Query: 770 LVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPR 829
G E+ + ++HPNIV L +V + + +++E G D+F++I +
Sbjct: 56 ----ATGHLFQ-EVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDEG-DMFDYIMKHEE 109
Query: 830 -MDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFH-VKLIDFGSATFMSKDS 887
++E L F Q+ A+ Y H L+++HR VKL DFG +
Sbjct: 110 GLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGK 169
Query: 888 LFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDT------IQ 941
+T G+ Y +PE+L G++Y P +++WS+G+ L++L PF + D+ +
Sbjct: 170 KLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD 229
Query: 942 GPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
T P VS++ + L+ ML +DP R ++ ++ +HPW++
Sbjct: 230 CKYTVPSHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQ 270
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 115 bits (276), Expect = 1e-24
Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY +++G G + V+ ++ KFI K ++ G +++ E+++L
Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRR--GVSREEIEREVNILR 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPNI++L D++EN+ +++E G +LF+F+ + + E + +Q+ V
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGG-ELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHS I H +KLIDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------- 956
+ + G E +MWS+G+ Y+L PF + +T Q LT V+ D ++
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGETKQETLTNISAVNYDFDEEYFSNTS 245
Query: 957 -----LLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI Q + H WIK
Sbjct: 246 ELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 115 bits (276), Expect = 1e-24
Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY +++G G + V+ ++ KFI K ++ G +++ E+++L
Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRR--GVSREEIEREVNILR 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPNI++L D++EN+ +++E G +LF+F+ + + E + +Q+ V
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGG-ELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHS I H +KLIDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------- 956
+ + G E +MWS+G+ Y+L PF + +T Q LT V+ D ++
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGETKQETLTNISAVNYDFDEEYFSNTS 245
Query: 957 -----LLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI Q + H WIK
Sbjct: 246 ELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 115 bits (276), Expect = 1e-24
Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY +++G G + V+ ++ KFI K ++ G +++ E+++L
Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRR--GVSREEIEREVNILR 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPNI++L D++EN+ +++E G +LF+F+ + + E + +Q+ V
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGG-ELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHS I H +KLIDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------- 956
+ + G E +MWS+G+ Y+L PF + +T Q LT V+ D ++
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGETKQETLTNISAVNYDFDEEYFSNTS 245
Query: 957 -----LLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI Q + H WIK
Sbjct: 246 ELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 115 bits (276), Expect = 1e-24
Identities = 76/271 (28%), Positives = 130/271 (47%), Gaps = 22/271 (8%)
Query: 728 HYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL 787
HY +++G G + V+ ++ KFI K ++ G +++ E+++L
Sbjct: 12 HYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRR--GVSREEIEREVNILR 69
Query: 788 TLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVE 847
++HPNI++L D++EN+ +++E G +LF+F+ + + E + +Q+ V
Sbjct: 70 EIRHPNIITLHDIFENKTDVVLILELVSGG-ELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 848 YLHSLNILH----RXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
YLHS I H +KLIDFG A + + F +GT E+ +PE+
Sbjct: 129 YLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEI 188
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------- 956
+ + G E +MWS+G+ Y+L PF + +T Q LT V+ D ++
Sbjct: 189 V-NYEPLGLEADMWSIGVITYILLSGASPF--LGETKQETLTNISAVNYDFDEEYFSNTS 245
Query: 957 -----LLRWMLCKDPANRCTITQLMSHPWIK 982
+R +L KDP R TI Q + H WIK
Sbjct: 246 ELAKDFIRRLLVKDPKRRMTIAQSLEHSWIK 276
>BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-dependent
protein kinase kinase 1, alpha protein.
Length = 505
Score = 114 bits (275), Expect = 1e-24
Identities = 102/352 (28%), Positives = 162/352 (46%), Gaps = 37/352 (10%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI-------------GPLFLVDGPD 775
Y +IGKGAYG V++AY S+ K + K+K+ G GP
Sbjct: 128 YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPA 187
Query: 776 GKKVPLE-----LSLLLTLKHPNIVSLVDVYEN--EKYFQMVMEKHGAGMDLFEFIERRP 828
+ +PLE +++L L H N+V L++V ++ E +V + G + E +P
Sbjct: 188 KQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKG-PVMEVPCDKP 246
Query: 829 RMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDS 887
+E Y+ R V +EYLH I+HR HVK+ DFG S F D+
Sbjct: 247 FSEEQARLYL-RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDA 305
Query: 888 LFSTFYGTTEYCSPEVLA--GNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTI 940
S+ GT + +PE ++ G ++G L++W+ G+TLY + PF D + I
Sbjct: 306 QLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKI 365
Query: 941 QG-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIID 997
+ P+ FP +SE+L+ L+ ML K+P R + + HPW+ ++ + E
Sbjct: 366 KNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNG--EEPLPSEEEH 423
Query: 998 CDRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
C E E N S + V V + ++RS NP E R EE+++S
Sbjct: 424 CSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMS 475
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein protein.
Length = 505
Score = 114 bits (275), Expect = 1e-24
Identities = 102/352 (28%), Positives = 162/352 (46%), Gaps = 37/352 (10%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI-------------GPLFLVDGPD 775
Y +IGKGAYG V++AY S+ K + K+K+ G GP
Sbjct: 128 YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPA 187
Query: 776 GKKVPLE-----LSLLLTLKHPNIVSLVDVYEN--EKYFQMVMEKHGAGMDLFEFIERRP 828
+ +PLE +++L L H N+V L++V ++ E +V + G + E +P
Sbjct: 188 KQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKG-PVMEVPCDKP 246
Query: 829 RMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDS 887
+E Y+ R V +EYLH I+HR HVK+ DFG S F D+
Sbjct: 247 FSEEQARLYL-RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDA 305
Query: 888 LFSTFYGTTEYCSPEVLA--GNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTI 940
S+ GT + +PE ++ G ++G L++W+ G+TLY + PF D + I
Sbjct: 306 QLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKI 365
Query: 941 QG-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIID 997
+ P+ FP +SE+L+ L+ ML K+P R + + HPW+ ++ + E
Sbjct: 366 KNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNG--EEPLPSEEEH 423
Query: 998 CDRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
C E E N S + V V + ++RS NP E R EE+++S
Sbjct: 424 CSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMS 475
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein protein.
Length = 505
Score = 114 bits (275), Expect = 1e-24
Identities = 102/352 (28%), Positives = 162/352 (46%), Gaps = 37/352 (10%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI-------------GPLFLVDGPD 775
Y +IGKGAYG V++AY S+ K + K+K+ G GP
Sbjct: 128 YKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAAQGGPA 187
Query: 776 GKKVPLE-----LSLLLTLKHPNIVSLVDVYEN--EKYFQMVMEKHGAGMDLFEFIERRP 828
+ +PLE +++L L H N+V L++V ++ E +V + G + E +P
Sbjct: 188 KQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKG-PVMEVPCDKP 246
Query: 829 RMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDS 887
+E Y+ R V +EYLH I+HR HVK+ DFG S F D+
Sbjct: 247 FSEEQARLYL-RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDA 305
Query: 888 LFSTFYGTTEYCSPEVLA--GNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTI 940
S+ GT + +PE ++ G ++G L++W+ G+TLY + PF D + I
Sbjct: 306 QLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKI 365
Query: 941 QG-PLTFPHL--VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEIID 997
+ P+ FP +SE+L+ L+ ML K+P R + + HPW+ ++ + E
Sbjct: 366 KNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNG--EEPLPSEEEH 423
Query: 998 CDRDEANPEMYYNGSLSPRSGSPVDQVDPVAKERS--NPSEVAVRSEEKNVS 1047
C E E N S + V V + ++RS NP E R EE+++S
Sbjct: 424 CSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMS 475
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 113 bits (273), Expect = 3e-24
Identities = 62/177 (35%), Positives = 89/177 (50%), Gaps = 7/177 (3%)
Query: 811 MEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXF 870
ME AG ++F+++ RM E FRQ+ AV Y H NI+HR
Sbjct: 1 MEYASAG-EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEA 59
Query: 871 HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFV 930
++K+ DFG + + S TF G+ Y +PE+ G KY GPE+++WS+G+ LY L
Sbjct: 60 NIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGS 119
Query: 931 DPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
PF E ++G P +S D E +LR L +PA RCT+ Q+M WI
Sbjct: 120 LPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 176
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 113 bits (271), Expect = 4e-24
Identities = 79/281 (28%), Positives = 130/281 (46%), Gaps = 13/281 (4%)
Query: 708 QSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGP 767
Q MS + E G+ Y +IG G + VK+ + K + K K+
Sbjct: 53 QDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKL-- 110
Query: 768 LFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERR 827
D + + E+S + L HPNI+ L +V E +VME G G +LF I
Sbjct: 111 ----DQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGG-ELFGKISTE 165
Query: 828 PRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDS 887
++ EP IF Q+ AV+++H I+HR VK+ DFG +T K
Sbjct: 166 GKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGE 225
Query: 888 LFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF-----SDIEDTI-Q 941
+ +TF G+ Y +PE+ Y G +++W++G+ LY + PF + ++ +I +
Sbjct: 226 MLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILE 285
Query: 942 GPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
G + P VSE +L+R +L + P R I +M+ W++
Sbjct: 286 GTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQ 326
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 113 bits (271), Expect = 4e-24
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y L+ IG+G++G V R+ + KFI K+G + + + E+ ++
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFI--PKLGR----SEKELRNLQREIEIMRG 57
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L+HPNIV ++D +E +K ++V+ A +LF+ +E ++ E + I Q+ A+ Y
Sbjct: 58 LRHPNIVHMLDSFETDK--EVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFST-FYGTTEYCSPEVLAGN 907
LHS ILHR +KL DFG A MS +++ T GT Y SPE++
Sbjct: 116 LHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEER 175
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
Y ++WS+G LY L PF + ++ P+ +P +S + L+ +
Sbjct: 176 PY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFLQGL 234
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAI 987
L KDP R + L+ HP+I HV I
Sbjct: 235 LTKDPRQRLSWPDLLYHPFIAGHVTI 260
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 113 bits (271), Expect = 4e-24
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y L+ IG+G++G V R+ + KFI K+G + + + E+ ++
Sbjct: 4 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFI--PKLGR----SEKELRNLQREIEIMRG 57
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L+HPNIV ++D +E +K ++V+ A +LF+ +E ++ E + I Q+ A+ Y
Sbjct: 58 LRHPNIVHMLDSFETDK--EVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYY 115
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFST-FYGTTEYCSPEVLAGN 907
LHS ILHR +KL DFG A MS +++ T GT Y SPE++
Sbjct: 116 LHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEER 175
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
Y ++WS+G LY L PF + ++ P+ +P +S + L+ +
Sbjct: 176 PY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGL 234
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAI 987
L KDP R + L+ HP+I HV I
Sbjct: 235 LTKDPRQRLSWPDLLYHPFIAGHVTI 260
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 113 bits (271), Expect = 4e-24
Identities = 80/266 (30%), Positives = 130/266 (48%), Gaps = 16/266 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y L+ IG+G++G V R+ + KFI K+G + + + E+ ++
Sbjct: 21 YHVLEMIGEGSFGRVYKGRRKYSAQVVALKFI--PKLGR----SEKELRNLQREIEIMRG 74
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L+HPNIV ++D +E +K ++V+ A +LF+ +E ++ E + I Q+ A+ Y
Sbjct: 75 LRHPNIVHMLDSFETDK--EVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYY 132
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFST-FYGTTEYCSPEVLAGN 907
LHS ILHR +KL DFG A MS +++ T GT Y SPE++
Sbjct: 133 LHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEER 192
Query: 908 KYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQLLRWM 961
Y ++WS+G LY L PF + ++ P+ +P +S + L+ +
Sbjct: 193 PY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGL 251
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAI 987
L KDP R + L+ HP+I HV I
Sbjct: 252 LTKDPRQRLSWPDLLYHPFIAGHVTI 277
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 112 bits (269), Expect = 8e-24
Identities = 85/266 (31%), Positives = 133/266 (50%), Gaps = 17/266 (6%)
Query: 726 SKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
S Y K IG+G Y VK A+ + + K I K GP + + +P EL +
Sbjct: 7 SNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMG-GPEEFIQ----RFLPRELQI 61
Query: 786 LLTLKHPNIVSLVDVYEN-EKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ TL H NI+ + ++ E+ + +VME G D+F+ + + E +FRQ+ +
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGG-DVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD--SLFSTFYGTTEYCSPE 902
A+ Y H + HR F++KL DFG A + K L TF G+T Y +PE
Sbjct: 121 AIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPE 179
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI---QGPLTFP-HL-VSEDLE 955
VL G + + ++WSMG+ LYV+ PF +DI + Q ++FP HL +S D +
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQ 239
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWI 981
LL+ +L D R +I ++ HPW+
Sbjct: 240 DLLKRLLEPDMILRPSIEEVSWHPWL 265
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 112 bits (269), Expect = 8e-24
Identities = 85/289 (29%), Positives = 131/289 (45%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ + K I +K+ D +K+ E
Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P ++MW+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T ++ + HPWI Q +A+ + E +DC
Sbjct: 242 TPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC 290
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 112 bits (269), Expect = 8e-24
Identities = 85/266 (31%), Positives = 133/266 (50%), Gaps = 17/266 (6%)
Query: 726 SKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
S Y K IG+G Y VK A+ + + K I K GP + + +P EL +
Sbjct: 7 SNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMG-GPEEFIQ----RFLPRELQI 61
Query: 786 LLTLKHPNIVSLVDVYEN-EKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ TL H NI+ + ++ E+ + +VME G D+F+ + + E +FRQ+ +
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGG-DVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD--SLFSTFYGTTEYCSPE 902
A+ Y H + HR F++KL DFG A + K L TF G+T Y +PE
Sbjct: 121 AIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPE 179
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI---QGPLTFP-HL-VSEDLE 955
VL G + + ++WSMG+ LYV+ PF +DI + Q ++FP HL +S D +
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQ 239
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWI 981
LL+ +L D R +I ++ HPW+
Sbjct: 240 DLLKRLLEPDMILRPSIEEVSWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 112 bits (269), Expect = 8e-24
Identities = 85/266 (31%), Positives = 133/266 (50%), Gaps = 17/266 (6%)
Query: 726 SKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
S Y K IG+G Y VK A+ + + K I K GP + + +P EL +
Sbjct: 7 SNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMG-GPEEFIQ----RFLPRELQI 61
Query: 786 LLTLKHPNIVSLVDVYEN-EKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ TL H NI+ + ++ E+ + +VME G D+F+ + + E +FRQ+ +
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGG-DVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD--SLFSTFYGTTEYCSPE 902
A+ Y H + HR F++KL DFG A + K L TF G+T Y +PE
Sbjct: 121 AIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPE 179
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI---QGPLTFP-HL-VSEDLE 955
VL G + + ++WSMG+ LYV+ PF +DI + Q ++FP HL +S D +
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQ 239
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWI 981
LL+ +L D R +I ++ HPW+
Sbjct: 240 DLLKRLLEPDMILRPSIEEVSWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 112 bits (269), Expect = 8e-24
Identities = 85/266 (31%), Positives = 133/266 (50%), Gaps = 17/266 (6%)
Query: 726 SKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSL 785
S Y K IG+G Y VK A+ + + K I K GP + + +P EL +
Sbjct: 7 SNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMG-GPEEFIQ----RFLPRELQI 61
Query: 786 LLTLKHPNIVSLVDVYEN-EKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ TL H NI+ + ++ E+ + +VME G D+F+ + + E +FRQ+ +
Sbjct: 62 VRTLDHKNIIQVYEMLESADGKICLVMELAEGG-DVFDCVLNGGPLPESRAKALFRQMVE 120
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD--SLFSTFYGTTEYCSPE 902
A+ Y H + HR F++KL DFG A + K L TF G+T Y +PE
Sbjct: 121 AIRYCHGCGVAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPE 179
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIEDTI---QGPLTFP-HL-VSEDLE 955
VL G + + ++WSMG+ LYV+ PF +DI + Q ++FP HL +S D +
Sbjct: 180 VLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQ 239
Query: 956 QLLRWMLCKDPANRCTITQLMSHPWI 981
LL+ +L D R +I ++ HPW+
Sbjct: 240 DLLKRLLEPDMILRPSIEEVSWHPWL 265
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 111 bits (268), Expect = 1e-23
Identities = 81/274 (29%), Positives = 131/274 (47%), Gaps = 22/274 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G GA+ V +A + + L K I KE + +G +G + E+++L +KHPNI
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEAL------EGKEGS-MENEIAVLHKIKHPNI 78
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
V+L D+YE+ + ++M+ G +LF+ I + E S + QV AV+YLH L I
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGG-ELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137
Query: 855 LHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+HR + + DFG + S+ ST GT Y +PEVLA Y+
Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYS- 196
Query: 912 PELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL--VSEDLEQLLRWM 961
++ WS+G+ Y+L PF D E ++ F P+ +S+ + +R +
Sbjct: 197 KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHL 256
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ KDP R T Q + HPWI A+ + +
Sbjct: 257 MEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSV 290
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 111 bits (268), Expect = 1e-23
Identities = 81/274 (29%), Positives = 131/274 (47%), Gaps = 22/274 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G GA+ V +A + + L K I KE + +G +G + E+++L +KHPNI
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEAL------EGKEGS-MENEIAVLHKIKHPNI 78
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
V+L D+YE+ + ++M+ G +LF+ I + E S + QV AV+YLH L I
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGG-ELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137
Query: 855 LHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+HR + + DFG + S+ ST GT Y +PEVLA Y+
Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYS- 196
Query: 912 PELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL--VSEDLEQLLRWM 961
++ WS+G+ Y+L PF D E ++ F P+ +S+ + +R +
Sbjct: 197 KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHL 256
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ KDP R T Q + HPWI A+ + +
Sbjct: 257 MEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSV 290
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 111 bits (268), Expect = 1e-23
Identities = 81/274 (29%), Positives = 131/274 (47%), Gaps = 22/274 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G GA+ V +A + + L K I KE + +G +G + E+++L +KHPNI
Sbjct: 26 LGTGAFSEVILAEDKRTQKLVAIKCIAKEAL------EGKEGS-MENEIAVLHKIKHPNI 78
Query: 795 VSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNI 854
V+L D+YE+ + ++M+ G +LF+ I + E S + QV AV+YLH L I
Sbjct: 79 VALDDIYESGGHLYLIMQLVSGG-ELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGI 137
Query: 855 LHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAG 911
+HR + + DFG + S+ ST GT Y +PEVLA Y+
Sbjct: 138 VHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYS- 196
Query: 912 PELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL--VSEDLEQLLRWM 961
++ WS+G+ Y+L PF D E ++ F P+ +S+ + +R +
Sbjct: 197 KAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHL 256
Query: 962 LCKDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ KDP R T Q + HPWI A+ + +
Sbjct: 257 MEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSV 290
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 111 bits (268), Expect = 1e-23
Identities = 58/169 (34%), Positives = 85/169 (50%), Gaps = 6/169 (3%)
Query: 819 DLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG 878
++F+++ RM E FRQ+ AV Y H NI+HR ++K+ DFG
Sbjct: 172 EVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFG 231
Query: 879 SATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD--- 935
+ + S TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF
Sbjct: 232 FSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNL 291
Query: 936 ---IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
E ++G P +S D E +LR L +PA RCT+ Q+M WI
Sbjct: 292 KELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWI 340
Score = 48.4 bits (110), Expect = 1e-04
Identities = 43/137 (31%), Positives = 64/137 (46%), Gaps = 13/137 (9%)
Query: 681 HNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAY 740
H T+ S +S D ++S G+R ++ S S ++ G Y L+ IGKG +
Sbjct: 18 HGTLGSGRSS--DKGPSWSSRSLGARCRN-SIASCPEEQPHVGNYR----LLRTIGKGNF 70
Query: 741 GCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDV 800
VK+A K I K ++ P L +K+ E+ ++ L HPNIV L +V
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSL------QKLFREVRIMKGLNHPNIVKLFEV 124
Query: 801 YENEKYFQMVMEKHGAG 817
E EK +VME AG
Sbjct: 125 IETEKTLYLVMEYASAG 141
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 516
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 495
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 529
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 527
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 516
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 495
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 529
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 527
Score = 111 bits (267), Expect = 1e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II gamma protein.
Length = 527
Score = 111 bits (266), Expect = 2e-23
Identities = 83/291 (28%), Positives = 132/291 (45%), Gaps = 23/291 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ +++ K I +K+ D +K+ E
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTPTQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCS 900
+V ++H +I+HR VKL DFG A + + F GT Y S
Sbjct: 123 SVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+ + + L+ ML +PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 242 TPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 292
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 263 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 322
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 323 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 440
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 441 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 500
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 501 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 530
>BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II delta protein.
Length = 478
Score = 110 bits (264), Expect = 3e-23
Identities = 99/370 (26%), Positives = 162/370 (43%), Gaps = 33/370 (8%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ + K I +K+ D +K+ E
Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
+V + H I+HR VKL DFG A + D + F GT Y S
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P ++MW+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMYY 1009
+ + + L+ ML +PA R T ++ + HPWI Q +A+ + E +DC + + N
Sbjct: 242 TPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLK-KFNARRKL 300
Query: 1010 NGS-----LSPRSGSPVDQV---DPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVALHA 1060
G+ L+ R+ S + KE + S + E+ ++E K + + A
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 1061 LSTADRDAHS 1070
++ D +A++
Sbjct: 361 INNGDFEAYT 370
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 129 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 188
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 189 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 246
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 247 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 306
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 307 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 366
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 367 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 396
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 263 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 322
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 323 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 380
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 381 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 440
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 441 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 500
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 501 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 530
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 110 bits (264), Expect = 3e-23
Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 18/270 (6%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y+ K +G GA G VK+A+ R K I K K + V E+ +L
Sbjct: 220 YIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKK 279
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
L HP I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+Y
Sbjct: 280 LNHPCIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQY 337
Query: 849 LHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 338 LHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV 397
Query: 906 GNKYAG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSE 952
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 398 SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSE 457
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 458 KALDLVKKLLVVDPKARFTTEEALRHPWLQ 487
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 109 bits (263), Expect = 4e-23
Identities = 99/370 (26%), Positives = 162/370 (43%), Gaps = 33/370 (8%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ + K I +K+ D +K+ E
Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQGYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
+V + H I+HR VKL DFG A + D + F GT Y S
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P ++MW+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMYY 1009
+ + + L+ ML +PA R T ++ + HPWI Q +A+ + E +DC + + N
Sbjct: 242 TPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLK-KFNARRKL 300
Query: 1010 NGS-----LSPRSGSPVDQV---DPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVALHA 1060
G+ L+ R+ S + KE + S + E+ ++E K + + A
Sbjct: 301 KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEA 360
Query: 1061 LSTADRDAHS 1070
++ D +A++
Sbjct: 361 INNGDFEAYT 370
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 109 bits (263), Expect = 4e-23
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ + K I +K+ D +K+ E
Sbjct: 40 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS------ARDHQKLEREAR 93
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 94 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 152
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
+V + H I+HR VKL DFG A + D + F GT Y S
Sbjct: 153 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 212
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P ++MW+ G+ LY+L PF D + G FP V
Sbjct: 213 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 271
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T ++ + HPWI Q +A+ + E +DC
Sbjct: 272 TPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDC 320
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent protein
kinase II alpha protein.
Length = 478
Score = 108 bits (260), Expect = 1e-22
Identities = 99/371 (26%), Positives = 168/371 (45%), Gaps = 34/371 (9%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+++ Y +++GKGA+ V RR ++L ++ K I + D +K+ E
Sbjct: 9 FTEEYQLFEELGKGAFSVV----RRCVKVLAGQEYAAK--IINTKKLSARDHQKLEREAR 62
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + ++ + G +LFE I R E S+ +Q+ +
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 121
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMS-KDSLFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + + + F GT Y S
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMYY 1009
+ + + L+ ML +P+ R T + + HPWI +A+ + E +DC + + N
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLK-KFNARRKL 299
Query: 1010 NGS-----LSPR--SG--SPVDQVDPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVALH 1059
G+ L+ R SG S ++ KE S + + E+ V ++E K + +
Sbjct: 300 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE 359
Query: 1060 ALSTADRDAHS 1070
A+S D ++++
Sbjct: 360 AISNGDFESYT 370
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 108 bits (260), Expect = 1e-22
Identities = 99/371 (26%), Positives = 168/371 (45%), Gaps = 34/371 (9%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+++ Y +++GKGA+ V RR ++L ++ K I + D +K+ E
Sbjct: 58 FTEEYQLFEELGKGAFSVV----RRCVKVLAGQEYAAK--IINTKKLSARDHQKLEREAR 111
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + ++ + G +LFE I R E S+ +Q+ +
Sbjct: 112 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 170
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMS-KDSLFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + + + F GT Y S
Sbjct: 171 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 230
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 231 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 289
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMYY 1009
+ + + L+ ML +P+ R T + + HPWI +A+ + E +DC + + N
Sbjct: 290 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLK-KFNARRKL 348
Query: 1010 NGS-----LSPR--SG--SPVDQVDPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVALH 1059
G+ L+ R SG S ++ KE S + + E+ V ++E K + +
Sbjct: 349 KGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIE 408
Query: 1060 ALSTADRDAHS 1070
A+S D ++++
Sbjct: 409 AISNGDFESYT 419
>BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-dependent
protein kinase (CaM kinase) II alpha protein.
Length = 478
Score = 108 bits (259), Expect = 1e-22
Identities = 101/372 (27%), Positives = 170/372 (45%), Gaps = 36/372 (9%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+++ Y +++GKGA+ V RR ++L ++ K I + D +K+ E
Sbjct: 9 FTEEYQLFEELGKGAFSVV----RRCVKVLAGQEYAAK--IINTKKLSARDHQKLEREAR 62
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + ++ + G +LFE I R E S+ +Q+ +
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 121
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMS-KDSLFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + + + F GT Y S
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQ-------GPLTFPH----L 949
PEVL + Y P +++W+ G+ LY+L PF D ED + G FP
Sbjct: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWD-EDQHRLYKQIKAGAYDFPSPEWDT 239
Query: 950 VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMY 1008
V+ + + L+ ML +P+ R T + + HPWI +A+ + E +DC + + N
Sbjct: 240 VTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLK-KFNARRK 298
Query: 1009 YNGS-----LSPR--SG--SPVDQVDPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVAL 1058
G+ L+ R SG S ++ KE S + + E+ V ++E K + +
Sbjct: 299 LKGAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLI 358
Query: 1059 HALSTADRDAHS 1070
A+S D ++++
Sbjct: 359 EAISNGDFESYT 370
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 107 bits (258), Expect = 2e-22
Identities = 84/289 (29%), Positives = 129/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y +++GKGA+ V+ + K I +K+ D +K+ E
Sbjct: 10 FTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLS------ARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
+V + H I+HR VKL DFG A + D + F GT Y S
Sbjct: 123 SVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P ++MW+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKDPYGKP-VDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T ++ + HPW Q +A+ + E +DC
Sbjct: 242 TPEAKDLINKMLTINPAKRITASEALKHPWTCQRSTVASMMHRQETVDC 290
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 107 bits (257), Expect = 2e-22
Identities = 79/266 (29%), Positives = 123/266 (46%), Gaps = 18/266 (6%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
K +G GA G VK+A+ R K I K K + V E+ +L L HP
Sbjct: 3 KTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHP 62
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
I+ + + ++ E Y+ +V+E G +LF+ + R+ E F Q+ AV+YLH
Sbjct: 63 CIIKIKNFFDAEDYY-IVLELMEGG-ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHEN 120
Query: 853 NILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKY 909
I+HR +K+ DFG + + + SL T GT Y +PEVL
Sbjct: 121 GIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGT 180
Query: 910 AG--PELEMWSMGITLYVLTFFVDPFSD------IEDTI-QGPLTF-PHL---VSEDLEQ 956
AG ++ WS+G+ L++ PFS+ ++D I G F P + VSE
Sbjct: 181 AGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALD 240
Query: 957 LLRWMLCKDPANRCTITQLMSHPWIK 982
L++ +L DP R T + + HPW++
Sbjct: 241 LVKKLLVVDPKARFTTEEALRHPWLQ 266
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 107 bits (257), Expect = 2e-22
Identities = 84/288 (29%), Positives = 134/288 (46%), Gaps = 23/288 (7%)
Query: 722 AGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPL 781
A + K + + +G GA+ V +A ++ L K I K+ + G + +
Sbjct: 16 AEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL------KGKESS-IEN 68
Query: 782 ELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQ 841
E+++L +KH NIV+L D+YE+ + +VM+ G +LF+ I + E S + RQ
Sbjct: 69 EIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGG-ELFDRIVEKGFYTEKDASTLIRQ 127
Query: 842 VGQAVEYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
V AV YLH + I+HR + + DFG + K + ST GT Y
Sbjct: 128 VLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGY 187
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTF--PHL- 949
+PEVLA Y+ ++ WS+G+ Y+L PF D E ++ F P+
Sbjct: 188 VAPEVLAQKPYS-KAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFHEII 996
+S+ + +R ++ KDP R T Q HPWI A+ N HE +
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTAL-NKNIHESV 293
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 107 bits (256), Expect = 3e-22
Identities = 76/265 (28%), Positives = 124/265 (46%), Gaps = 22/265 (8%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+++G G + VK +S L KFI K + G +++ E+S+L + H
Sbjct: 27 EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRR--GVSREEIEREVSILRQVLHH 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
N+++L DVYEN +++E G +LF+F+ ++ + E + +Q+ V YLH+
Sbjct: 85 NVITLHDVYENRTDVVLILELVSGG-ELFDFLAQKESLSEEEATSFIKQILDGVNYLHTK 143
Query: 853 NILHRXXXXXXXXXXXXF----HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
I H H+KLIDFG A + F +GT E+ +PE++ +
Sbjct: 144 KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV-NYE 202
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------------ 956
G E +MWS+G+ Y+L PF + DT Q L VS D ++
Sbjct: 203 PLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANITAVSYDFDEEFFSQTSELAKD 260
Query: 957 LLRWMLCKDPANRCTITQLMSHPWI 981
+R +L K+ R TI + + HPWI
Sbjct: 261 FIRKLLVKETRKRLTIQEALRHPWI 285
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 107 bits (256), Expect = 3e-22
Identities = 82/289 (28%), Positives = 133/289 (46%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+++ Y +++GKGA+ V RR ++L ++ K I + D +K+ E
Sbjct: 9 FTEEYQLFEELGKGAFSVV----RRCVKVLAGQEYAAK--IINTKKLSARDHQKLEREAR 62
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + ++ + G +LFE I R E S+ +Q+ +
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 121
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMS-KDSLFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + + + F GT Y S
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +P+ R T + + HPWI +A+ + E +DC
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDC 289
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 107 bits (256), Expect = 3e-22
Identities = 82/289 (28%), Positives = 133/289 (46%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
+++ Y +++GKGA+ V RR ++L ++ K I + D +K+ E
Sbjct: 9 FTEEYQLFEELGKGAFSVV----RRCVKVLAGQEYAAK--IINTKKLSARDHQKLEREAR 62
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKHPNIV L D E + ++ + G +LFE I R E S+ +Q+ +
Sbjct: 63 ICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 121
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMS-KDSLFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + + + F GT Y S
Sbjct: 122 AVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLS 181
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL + Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 182 PEVLRKDPYGKP-VDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV 240
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +P+ R T + + HPWI +A+ + E +DC
Sbjct: 241 TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDC 289
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 107 bits (256), Expect = 3e-22
Identities = 76/265 (28%), Positives = 124/265 (46%), Gaps = 22/265 (8%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+++G G + VK +S L KFI K + G +++ E+S+L + H
Sbjct: 27 EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRR--GVSREEIEREVSILRQVLHH 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
N+++L DVYEN +++E G +LF+F+ ++ + E + +Q+ V YLH+
Sbjct: 85 NVITLHDVYENRTDVVLILELVSGG-ELFDFLAQKESLSEEEATSFIKQILDGVNYLHTK 143
Query: 853 NILHRXXXXXXXXXXXXF----HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
I H H+KLIDFG A + F +GT E+ +PE++ +
Sbjct: 144 KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV-NYE 202
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSDIEDTIQGPLTFPHLVSEDLEQ------------ 956
G E +MWS+G+ Y+L PF + DT Q L VS D ++
Sbjct: 203 PLGLEADMWSIGVITYILLSGASPF--LGDTKQETLANITAVSYDFDEEFFSQTSELAKD 260
Query: 957 LLRWMLCKDPANRCTITQLMSHPWI 981
+R +L K+ R TI + + HPWI
Sbjct: 261 FIRKLLVKETRKRLTIQEALRHPWI 285
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 106 bits (255), Expect = 4e-22
Identities = 75/264 (28%), Positives = 123/264 (46%), Gaps = 20/264 (7%)
Query: 733 KQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHP 792
+++G G + VK +S L KFI K + G +++ E+S+L + H
Sbjct: 27 EELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRR--GVSREEIEREVSILRQVLHH 84
Query: 793 NIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSL 852
N+++L DVYEN +++E G +LF+F+ ++ + E + +Q+ V YLH+
Sbjct: 85 NVITLHDVYENRTDVVLILELVSGG-ELFDFLAQKESLSEEEATSFIKQILDGVNYLHTK 143
Query: 853 NILHRXXXXXXXXXXXXF----HVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNK 908
I H H+KLIDFG A + F +GT E+ +PE++ +
Sbjct: 144 KIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV-NYE 202
Query: 909 YAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQGPLT----------FPHLVSEDLEQL 957
G E +MWS+G+ Y+L PF D + +T F H SE +
Sbjct: 203 PLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITSVSYDFDEEFFSH-TSELAKDF 261
Query: 958 LRWMLCKDPANRCTITQLMSHPWI 981
+R +L K+ R TI + + HPWI
Sbjct: 262 IRKLLVKETRKRLTIQEALRHPWI 285
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 105 bits (253), Expect = 7e-22
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)
Query: 775 DGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPL 834
D K V E+ +LL L HPNI+ L +++E +V+E G +LF+ I + E
Sbjct: 82 DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG-ELFDRIVEKGYYSERD 140
Query: 835 LSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX---XFHVKLIDFGSATFMSKDSLFST 891
+ +Q+ +AV YLH I+HR +K+ DFG + + L T
Sbjct: 141 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT 200
Query: 892 FYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD---IEDTIQGPLTFPH 948
GT YC+PE+L G Y GPE++MWS+GI Y+L +PF D + + L +
Sbjct: 201 VCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEY 259
Query: 949 L--------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
VS + + L+R ++ DP R T Q + HPW+
Sbjct: 260 YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 105 bits (253), Expect = 7e-22
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)
Query: 775 DGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPL 834
D K V E+ +LL L HPNI+ L +++E +V+E G +LF+ I + E
Sbjct: 82 DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG-ELFDRIVEKGYYSERD 140
Query: 835 LSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX---XFHVKLIDFGSATFMSKDSLFST 891
+ +Q+ +AV YLH I+HR +K+ DFG + + L T
Sbjct: 141 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT 200
Query: 892 FYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD---IEDTIQGPLTFPH 948
GT YC+PE+L G Y GPE++MWS+GI Y+L +PF D + + L +
Sbjct: 201 VCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEY 259
Query: 949 L--------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
VS + + L+R ++ DP R T Q + HPW+
Sbjct: 260 YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 105 bits (253), Expect = 7e-22
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)
Query: 775 DGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPL 834
D K V E+ +LL L HPNI+ L +++E +V+E G +LF+ I + E
Sbjct: 82 DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG-ELFDRIVEKGYYSERD 140
Query: 835 LSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX---XFHVKLIDFGSATFMSKDSLFST 891
+ +Q+ +AV YLH I+HR +K+ DFG + + L T
Sbjct: 141 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT 200
Query: 892 FYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD---IEDTIQGPLTFPH 948
GT YC+PE+L G Y GPE++MWS+GI Y+L +PF D + + L +
Sbjct: 201 VCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEY 259
Query: 949 L--------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
VS + + L+R ++ DP R T Q + HPW+
Sbjct: 260 YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 105 bits (253), Expect = 7e-22
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)
Query: 775 DGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPL 834
D K V E+ +LL L HPNI+ L +++E +V+E G +LF+ I + E
Sbjct: 82 DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG-ELFDRIVEKGYYSERD 140
Query: 835 LSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX---XFHVKLIDFGSATFMSKDSLFST 891
+ +Q+ +AV YLH I+HR +K+ DFG + + L T
Sbjct: 141 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT 200
Query: 892 FYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD---IEDTIQGPLTFPH 948
GT YC+PE+L G Y GPE++MWS+GI Y+L +PF D + + L +
Sbjct: 201 VCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEY 259
Query: 949 L--------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
VS + + L+R ++ DP R T Q + HPW+
Sbjct: 260 YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 105 bits (253), Expect = 7e-22
Identities = 70/221 (31%), Positives = 107/221 (48%), Gaps = 16/221 (7%)
Query: 775 DGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPL 834
D K V E+ +LL L HPNI+ L +++E +V+E G +LF+ I + E
Sbjct: 112 DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGG-ELFDRIVEKGYYSERD 170
Query: 835 LSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXX---XFHVKLIDFGSATFMSKDSLFST 891
+ +Q+ +AV YLH I+HR +K+ DFG + + L T
Sbjct: 171 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKT 230
Query: 892 FYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD---IEDTIQGPLTFPH 948
GT YC+PE+L G Y GPE++MWS+GI Y+L +PF D + + L +
Sbjct: 231 VCGTPGYCAPEILRGCAY-GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEY 289
Query: 949 L--------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
VS + + L+R ++ DP R T Q + HPW+
Sbjct: 290 YFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 330
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 105 bits (253), Expect = 7e-22
Identities = 82/279 (29%), Positives = 131/279 (46%), Gaps = 29/279 (10%)
Query: 721 VAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKI-GPLFLVDGPDGKKV 779
+A KHY T + IG G + VK R R K I K ++ G +VD
Sbjct: 308 IAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDS------ 361
Query: 780 PLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIF 839
E+ ++ +L HPNIV L +VYE + +++E + G DLF+ I + EP + +
Sbjct: 362 --EILIIQSLSHPNIVKLHEVYETDMEIYLILE-YVQGGDLFDAIIESVKFPEPDAALMI 418
Query: 840 RQVGQAVEYLHSLNILHR----XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGT 895
+ +A+ ++H +I+HR +KL DFG A + + +F T GT
Sbjct: 419 MDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVR-PIF-TVCGT 476
Query: 896 TEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSDIE---DTIQGPLTFPHL--- 949
Y +PE+L+ Y G E++MW+ G+ LY+L PF E D + + H
Sbjct: 477 PTYVAPEILSEKGY-GLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFL 535
Query: 950 ------VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIK 982
+S+ + L+ +L DP R T Q++ HPWI+
Sbjct: 536 PPYWDNISDAAKDLVSRLLVVDPKKRYTAHQVLQHPWIE 574
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 105 bits (252), Expect = 9e-22
Identities = 85/289 (29%), Positives = 131/289 (45%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ ++ E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMYRQETVEC 290
>U43784-1|AAC50428.1| 382|Homo sapiens mitogen activated protein
kinase activated protein kinase-3 protein.
Length = 382
Score = 105 bits (251), Expect = 1e-21
Identities = 80/235 (34%), Positives = 117/235 (49%), Gaps = 28/235 (11%)
Query: 792 PNIVSLVDVYEN----EKYFQMVMEKHGAGMDLFEFIERR--PRMDEPLLSYIFRQVGQA 845
P+IV ++DVYEN ++ ++ME G +LF I+ R E + I R +G A
Sbjct: 95 PHIVCILDVYENMHHGKRCLLIIMECMEGG-ELFSRIQERGDQAFTEREAAEIMRDIGTA 153
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPE 902
+++LHS NI HR +KL DFG A ++++L + Y T Y +PE
Sbjct: 154 IQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCY-TPYYVAPE 212
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQ---------GPLTFPHL--- 949
VL KY +MWS+G+ +Y+L PF S+ I G FP+
Sbjct: 213 VLGPEKY-DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH--EIIDCDRD 1001
VSED +QL+R +L DP R TITQ M+HPWI Q + + H ++ D+D
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKD 326
>U09578-1|AAD09136.1| 382|Homo sapiens MAPKAP kinase protein.
Length = 382
Score = 105 bits (251), Expect = 1e-21
Identities = 80/235 (34%), Positives = 117/235 (49%), Gaps = 28/235 (11%)
Query: 792 PNIVSLVDVYEN----EKYFQMVMEKHGAGMDLFEFIERR--PRMDEPLLSYIFRQVGQA 845
P+IV ++DVYEN ++ ++ME G +LF I+ R E + I R +G A
Sbjct: 95 PHIVCILDVYENMHHGKRCLLIIMECMEGG-ELFSRIQERGDQAFTEREAAEIMRDIGTA 153
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPE 902
+++LHS NI HR +KL DFG A ++++L + Y T Y +PE
Sbjct: 154 IQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCY-TPYYVAPE 212
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQ---------GPLTFPHL--- 949
VL KY +MWS+G+ +Y+L PF S+ I G FP+
Sbjct: 213 VLGPEKY-DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH--EIIDCDRD 1001
VSED +QL+R +L DP R TITQ M+HPWI Q + + H ++ D+D
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKD 326
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 105 bits (251), Expect = 1e-21
Identities = 80/282 (28%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLL 786
K ++ ++ +G GA+ V + +R L K I K P F + E+++L
Sbjct: 21 KTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS---PAFRDSSLEN-----EIAVL 72
Query: 787 LTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAV 846
+KH NIV+L D+YE+ ++ +VM+ G +LF+ I R E S + +QV AV
Sbjct: 73 KKIKHENIVTLEDIYESTTHYYLVMQLVSGG-ELFDRILERGVYTEKDASLVIQQVLSAV 131
Query: 847 EYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
+YLH I+HR + + DFG + M ++ + ST GT Y +PEV
Sbjct: 132 KYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV 190
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
LA Y+ ++ WS+G+ Y+L PF + E +G F +D+ +
Sbjct: 191 LAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISES 249
Query: 958 LRWMLC----KDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ +C KDP R T + +SHPWI + A+ ++ +
Sbjct: 250 AKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSV 291
>BC010407-1|AAH10407.1| 382|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 3 protein.
Length = 382
Score = 105 bits (251), Expect = 1e-21
Identities = 80/235 (34%), Positives = 117/235 (49%), Gaps = 28/235 (11%)
Query: 792 PNIVSLVDVYEN----EKYFQMVMEKHGAGMDLFEFIERR--PRMDEPLLSYIFRQVGQA 845
P+IV ++DVYEN ++ ++ME G +LF I+ R E + I R +G A
Sbjct: 95 PHIVCILDVYENMHHGKRCLLIIMECMEGG-ELFSRIQERGDQAFTEREAAEIMRDIGTA 153
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPE 902
+++LHS NI HR +KL DFG A ++++L + Y T Y +PE
Sbjct: 154 IQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCY-TPYYVAPE 212
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQ---------GPLTFPHL--- 949
VL KY +MWS+G+ +Y+L PF S+ I G FP+
Sbjct: 213 VLGPEKY-DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH--EIIDCDRD 1001
VSED +QL+R +L DP R TITQ M+HPWI Q + + H ++ D+D
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKD 326
>BC007591-1|AAH07591.1| 382|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 3 protein.
Length = 382
Score = 105 bits (251), Expect = 1e-21
Identities = 80/235 (34%), Positives = 117/235 (49%), Gaps = 28/235 (11%)
Query: 792 PNIVSLVDVYEN----EKYFQMVMEKHGAGMDLFEFIERR--PRMDEPLLSYIFRQVGQA 845
P+IV ++DVYEN ++ ++ME G +LF I+ R E + I R +G A
Sbjct: 95 PHIVCILDVYENMHHGKRCLLIIMECMEGG-ELFSRIQERGDQAFTEREAAEIMRDIGTA 153
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPE 902
+++LHS NI HR +KL DFG A ++++L + Y T Y +PE
Sbjct: 154 IQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCY-TPYYVAPE 212
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQ---------GPLTFPHL--- 949
VL KY +MWS+G+ +Y+L PF S+ I G FP+
Sbjct: 213 VLGPEKY-DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH--EIIDCDRD 1001
VSED +QL+R +L DP R TITQ M+HPWI Q + + H ++ D+D
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKD 326
>BC001662-1|AAH01662.1| 382|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 3 protein.
Length = 382
Score = 105 bits (251), Expect = 1e-21
Identities = 80/235 (34%), Positives = 117/235 (49%), Gaps = 28/235 (11%)
Query: 792 PNIVSLVDVYEN----EKYFQMVMEKHGAGMDLFEFIERR--PRMDEPLLSYIFRQVGQA 845
P+IV ++DVYEN ++ ++ME G +LF I+ R E + I R +G A
Sbjct: 95 PHIVCILDVYENMHHGKRCLLIIMECMEGG-ELFSRIQERGDQAFTEREAAEIMRDIGTA 153
Query: 846 VEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDSLFSTFYGTTEYCSPE 902
+++LHS NI HR +KL DFG A ++++L + Y T Y +PE
Sbjct: 154 IQFLHSHNIAHRDVKPENLLYTSKEKDAVLKLTDFGFAKETTQNALQTPCY-TPYYVAPE 212
Query: 903 VLAGNKYAGPELEMWSMGITLYVLTFFVDPF-SDIEDTIQ---------GPLTFPHL--- 949
VL KY +MWS+G+ +Y+L PF S+ I G FP+
Sbjct: 213 VLGPEKY-DKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRLGQYGFPNPEWS 271
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH--EIIDCDRD 1001
VSED +QL+R +L DP R TITQ M+HPWI Q + + H ++ D+D
Sbjct: 272 EVSEDAKQLIRLLLKTDPTERLTITQFMNHPWINQSMVVPQTPLHTARVLQEDKD 326
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 105 bits (251), Expect = 1e-21
Identities = 80/282 (28%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLL 786
K ++ ++ +G GA+ V + +R L K I K P F + E+++L
Sbjct: 21 KTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS---PAFRDSSLEN-----EIAVL 72
Query: 787 LTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAV 846
+KH NIV+L D+YE+ ++ +VM+ G +LF+ I R E S + +QV AV
Sbjct: 73 KKIKHENIVTLEDIYESTTHYYLVMQLVSGG-ELFDRILERGVYTEKDASLVIQQVLSAV 131
Query: 847 EYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
+YLH I+HR + + DFG + M ++ + ST GT Y +PEV
Sbjct: 132 KYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV 190
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
LA Y+ ++ WS+G+ Y+L PF + E +G F +D+ +
Sbjct: 191 LAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISES 249
Query: 958 LRWMLC----KDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ +C KDP R T + +SHPWI + A+ ++ +
Sbjct: 250 AKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSV 291
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 105 bits (251), Expect = 1e-21
Identities = 80/282 (28%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLL 786
K ++ ++ +G GA+ V + +R L K I K P F + E+++L
Sbjct: 26 KTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS---PAFRDSSLEN-----EIAVL 77
Query: 787 LTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAV 846
+KH NIV+L D+YE+ ++ +VM+ G +LF+ I R E S + +QV AV
Sbjct: 78 KKIKHENIVTLEDIYESTTHYYLVMQLVSGG-ELFDRILERGVYTEKDASLVIQQVLSAV 136
Query: 847 EYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
+YLH I+HR + + DFG + M ++ + ST GT Y +PEV
Sbjct: 137 KYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV 195
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
LA Y+ ++ WS+G+ Y+L PF + E +G F +D+ +
Sbjct: 196 LAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISES 254
Query: 958 LRWMLC----KDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ +C KDP R T + +SHPWI + A+ ++ +
Sbjct: 255 AKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSV 296
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 105 bits (251), Expect = 1e-21
Identities = 80/282 (28%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLL 786
K ++ ++ +G GA+ V + +R L K I K P F + E+++L
Sbjct: 21 KTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS---PAFRDSSLEN-----EIAVL 72
Query: 787 LTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAV 846
+KH NIV+L D+YE+ ++ +VM+ G +LF+ I R E S + +QV AV
Sbjct: 73 KKIKHENIVTLEDIYESTTHYYLVMQLVSGG-ELFDRILERGVYTEKDASLVIQQVLSAV 131
Query: 847 EYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
+YLH I+HR + + DFG + M ++ + ST GT Y +PEV
Sbjct: 132 KYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV 190
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
LA Y+ ++ WS+G+ Y+L PF + E +G F +D+ +
Sbjct: 191 LAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISES 249
Query: 958 LRWMLC----KDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ +C KDP R T + +SHPWI + A+ ++ +
Sbjct: 250 AKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSV 291
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 105 bits (251), Expect = 1e-21
Identities = 69/210 (32%), Positives = 106/210 (50%), Gaps = 18/210 (8%)
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEY 848
++HPNI L+D+ E E + +VME G +L I + R++E RQ+ AVE+
Sbjct: 118 IRHPNITQLLDILETENSYYLVMELCPGG-NLMHKIYEKKRLEESEARRYIRQLISAVEH 176
Query: 849 LHSLNILHRXXXXXXXXXXXXFHVKLIDFG---SATFMSKDSLFSTFYGTTEYCSPEVLA 905
LH ++HR ++KLIDFG A + FST G+ Y +PE+LA
Sbjct: 177 LHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLA 236
Query: 906 GNKYAGPELEMWSMGITLY-----VLTFFVDPFS------DIEDTIQGPLTFPHLVSEDL 954
KY GP++++WS+G+ +Y L F V+PFS + D PL P +S
Sbjct: 237 RKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPL--PTQLSTGA 293
Query: 955 EQLLRWMLCKDPANRCTITQLMSHPWIKQH 984
LR +L DP R I Q +++ W+ ++
Sbjct: 294 ISFLRSLLEPDPVKRPNIQQALANRWLNEN 323
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 105 bits (251), Expect = 1e-21
Identities = 80/282 (28%), Positives = 133/282 (47%), Gaps = 24/282 (8%)
Query: 727 KHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLL 786
K ++ ++ +G GA+ V + +R L K I K P F + E+++L
Sbjct: 21 KTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS---PAFRDSSLEN-----EIAVL 72
Query: 787 LTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAV 846
+KH NIV+L D+YE+ ++ +VM+ G +LF+ I R E S + +QV AV
Sbjct: 73 KKIKHENIVTLEDIYESTTHYYLVMQLVSGG-ELFDRILERGVYTEKDASLVIQQVLSAV 131
Query: 847 EYLHSLNILHRX---XXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEV 903
+YLH I+HR + + DFG + M ++ + ST GT Y +PEV
Sbjct: 132 KYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK-MEQNGIMSTACGTPGYVAPEV 190
Query: 904 LAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPHLVSEDLEQL 957
LA Y+ ++ WS+G+ Y+L PF + E +G F +D+ +
Sbjct: 191 LAQKPYS-KAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISES 249
Query: 958 LRWMLC----KDPANRCTITQLMSHPWIKQHVAIANYVFHEI 995
+ +C KDP R T + +SHPWI + A+ ++ +
Sbjct: 250 AKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSV 291
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin dependent
protein kinase II beta 2 protein.
Length = 479
Score = 104 bits (250), Expect = 2e-21
Identities = 99/371 (26%), Positives = 165/371 (44%), Gaps = 34/371 (9%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDRDEANPEMYY 1009
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C + + N
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLK-KFNARRKL 300
Query: 1010 NGS-----LSPRSGSP----VDQVDPVAKERSNPSEVAVRSEEKNVSREE-PKRSSVALH 1059
G+ L+ R+ S +++ KE S+ + + E+ ++E K + +
Sbjct: 301 KGAILTTMLATRNFSAAKSLLNKKADGVKESSDSANTTIEDEDAKARKQEIIKTTEQLIE 360
Query: 1060 ALSTADRDAHS 1070
A++ D +A++
Sbjct: 361 AVNNGDFEAYA 371
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 103 bits (248), Expect = 3e-21
Identities = 85/289 (29%), Positives = 130/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ LKH NIV L D E + +V + G +LFE I R E S+ +Q+ +
Sbjct: 64 ICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILE 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein
protein.
Length = 365
Score = 103 bits (247), Expect = 4e-21
Identities = 86/299 (28%), Positives = 137/299 (45%), Gaps = 22/299 (7%)
Query: 803 NEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXX 862
NE + MV E G + E +P + E + F+ + + +EYLH I+HR
Sbjct: 68 NEDHLYMVFELVNQG-PVMEVPTLKP-LSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPS 125
Query: 863 XXXXXXXFHVKLIDFG-SATFMSKDSLFSTFYGTTEYCSPEVLAGNK--YAGPELEMWSM 919
H+K+ DFG S F D+L S GT + +PE L+ + ++G L++W+M
Sbjct: 126 NLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAM 185
Query: 920 GITLYVLTFFVDPFSD-----IEDTIQGP-LTFPHL--VSEDLEQLLRWMLCKDPANRCT 971
G+TLY F PF D + I+ L FP ++EDL+ L+ ML K+P +R
Sbjct: 186 GVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIV 245
Query: 972 ITQLMSHPWIKQHVAIANYVFHEIIDCDRDEANPEMYYNGSLSPRSGSPVDQVDPVAKER 1031
+ ++ HPW+ +H A + E +C E E N S + V V + ++R
Sbjct: 246 VPEIKLHPWVTRHG--AEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKR 303
Query: 1032 S--NPSEVAVRSEEK-----NVSREEPKRSSVALHALSTADRDAHSDNYSLRSSADILD 1083
S NP E + R E N+ ++P R +L L + D+ + +A LD
Sbjct: 304 SFGNPFEGSRREERSLSAPGNLLTKKPTRECESLSELKGTKKKKGLDSMTSTVAAGWLD 362
>AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-dependent
protein kinase II gamma protein.
Length = 566
Score = 102 bits (245), Expect = 6e-21
Identities = 80/278 (28%), Positives = 124/278 (44%), Gaps = 23/278 (8%)
Query: 738 GAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSL 797
GA+ V+ +++ K I +K+ D +K+ E + LKHPNIV L
Sbjct: 1 GAFSVVRRCVKKTSTQEYAAKIINTKKLS------ARDHQKLEREARICRLLKHPNIVRL 54
Query: 798 VDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR 857
D E + +V + G +LFE I R E S+ Q+ ++V ++H +I+HR
Sbjct: 55 HDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHR 113
Query: 858 XXXXXXXXXXXXFH---VKLIDFGSAT-FMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPE 913
VKL DFG A + + F GT Y SPEVL + Y P
Sbjct: 114 DLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKP- 172
Query: 914 LEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LVSEDLEQLLRWMLC 963
+++W+ G+ LY+L PF D + G FP V+ + + L+ ML
Sbjct: 173 VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLT 232
Query: 964 KDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDCDR 1000
+PA R T Q + HPW+ Q +A+ + E ++C R
Sbjct: 233 INPAKRITADQALKHPWVCQRSTVASMMHRQETVECLR 270
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 102 bits (244), Expect = 8e-21
Identities = 77/281 (27%), Positives = 124/281 (44%), Gaps = 38/281 (13%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 41 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 97
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNI ++F+++
Sbjct: 98 PTSL------QKLFREVRIMKILNHPNIG-----------------------EVFDYLVA 128
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 129 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 188
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 189 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 248
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 249 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 289
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 102 bits (244), Expect = 8e-21
Identities = 53/175 (30%), Positives = 88/175 (50%), Gaps = 6/175 (3%)
Query: 813 KHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHV 872
++ +G ++F+++ RM E FRQ+ AV+Y H I+HR ++
Sbjct: 2 EYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNI 61
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
K+ DFG + + + TF G+ Y +PE+ G KY GPE+++WS+G+ LY L P
Sbjct: 62 KIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLP 121
Query: 933 FSD------IEDTIQGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
F E ++G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 122 FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 176
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 102 bits (244), Expect = 8e-21
Identities = 77/281 (27%), Positives = 124/281 (44%), Gaps = 38/281 (13%)
Query: 707 PQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIG 766
P+ + ++ DEQ + +Y K IGKG + VK+A K I K ++
Sbjct: 153 PRCRNSITSATDEQ---PHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLN 209
Query: 767 PLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIER 826
P L +K+ E+ ++ L HPNI ++F+++
Sbjct: 210 PTSL------QKLFREVRIMKILNHPNIG-----------------------EVFDYLVA 240
Query: 827 RPRMDEPLLSYIFRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD 886
RM E FRQ+ AV+Y H I+HR ++K+ DFG + +
Sbjct: 241 HGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVG 300
Query: 887 SLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTI 940
+ TF G+ Y +PE+ G KY GPE+++WS+G+ LY L PF E +
Sbjct: 301 NKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVL 360
Query: 941 QGPLTFPHLVSEDLEQLLRWMLCKDPANRCTITQLMSHPWI 981
+G P +S D E LL+ +L +P R ++ Q+M W+
Sbjct: 361 RGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWM 401
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 41 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 93
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 94 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 146
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 147 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 205
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 206 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 262
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 263 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 322
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 323 VDVDQRFSAVQVLEHPWV 340
>AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 348 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 400
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 401 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 453
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 454 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 512
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 513 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 569
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 570 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 629
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 630 VDVDQRFSAVQVLEHPWV 647
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 101 bits (242), Expect = 1e-20
Identities = 84/289 (29%), Positives = 129/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ +KH NIV L D E + +V + G +LFE I R E S+ +Q+
Sbjct: 64 ICRLVKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILX 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 101 bits (242), Expect = 1e-20
Identities = 84/289 (29%), Positives = 129/289 (44%), Gaps = 23/289 (7%)
Query: 725 YSKHYVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELS 784
++ Y + IGKGA+ V RR +L T ++ K I + D +K+ E
Sbjct: 10 FTDEYQLYEDIGKGAFSVV----RRCVKLCTGHEYAAK--IINTKKLSARDHQKLEREAR 63
Query: 785 LLLTLKHPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQ 844
+ +KH NIV L D E + +V + G +LFE I R E S+ +Q+
Sbjct: 64 ICRLVKHSNIVRLHDSISEEGFHYLVFDLVTGG-ELFEDIVAREYYSEADASHCIQQILX 122
Query: 845 AVEYLHSLNILHRXXXXXXXXXXXXFH---VKLIDFGSATFMSKDS-LFSTFYGTTEYCS 900
AV + H + ++HR VKL DFG A + D + F GT Y S
Sbjct: 123 AVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLS 182
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD------IEDTIQGPLTFPH----LV 950
PEVL Y P +++W+ G+ LY+L PF D + G FP V
Sbjct: 183 PEVLRKEAYGKP-VDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTV 241
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVF-HEIIDC 998
+ + + L+ ML +PA R T + + HPW+ Q +A+ + E ++C
Sbjct: 242 TPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVEC 290
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 101 bits (242), Expect = 1e-20
Identities = 90/318 (28%), Positives = 138/318 (43%), Gaps = 34/318 (10%)
Query: 680 RHNTVASSLTSTADNSLVLGNKSAGSRPQSMSFVSQGGDEQVAGEYSKHYVTLKQIGKGA 739
+H ++SL ST S + N G F Q+ ++ Y + IG G
Sbjct: 413 QHGGSSTSLASTKVCSSMDENDGPGEEVSEEGF-------QIPATITERYKVGRTIGDGN 465
Query: 740 YGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVD 799
+ VK RS K I K K G + + E+S+L +KHPNIV L++
Sbjct: 466 FAVVKECVERSTAREYALKIIKKSKCR------GKE-HMIQNEVSILRRVKHPNIVLLIE 518
Query: 800 VYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLNILHR-- 857
+ +VME G DLF+ I + E S + + A++YLHSLNI+HR
Sbjct: 519 EMDVPTELYLVMELVKGG-DLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDI 577
Query: 858 --XXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELE 915
+KL DFG AT + D T GT Y +PE++A Y G +++
Sbjct: 578 KPENLLVYEHQDGSKSLKLGDFGLATIV--DGPLYTVCGTPTYVAPEIIAETGY-GLKVD 634
Query: 916 MWSMGITLYVLTFFVDPFSD--------IEDTIQGPLTFP----HLVSEDLEQLLRWMLC 963
+W+ G+ Y+L PF + + G + FP VS+ ++L+ ML
Sbjct: 635 IWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLL 694
Query: 964 KDPANRCTITQLMSHPWI 981
D R + Q++ HPW+
Sbjct: 695 VDVDQRFSAVQVLEHPWV 712
>U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated protein
kinase 2 protein.
Length = 370
Score = 101 bits (241), Expect = 2e-20
Identities = 83/255 (32%), Positives = 123/255 (48%), Gaps = 27/255 (10%)
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYEN----EKYFQMVMEKHGAG 817
+EK L D P ++ +EL + + P+IV +VDVYEN K +VME G
Sbjct: 87 QEKFALKMLQDCPKARR-EVELHWRAS-QCPHIVRIVDVYENLYAGRKCLLIVMECLDGG 144
Query: 818 MDLFEFIERR--PRMDEPLLSYIFRQVGQAVEYLHSLNILHRX---XXXXXXXXXXXFHV 872
+LF I+ R E S I + +G+A++YLHS+NI HR +
Sbjct: 145 -ELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAIL 203
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
KL DFG A + + +T T Y +PEVL KY +MWS+G+ +Y+L P
Sbjct: 204 KLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY-DKSCDMWSLGVIMYILLCGYPP 262
Query: 933 F---------SDIEDTIQ-GPLTFPH----LVSEDLEQLLRWMLCKDPANRCTITQLMSH 978
F ++ I+ G FP+ VSE+++ L+R +L +P R TIT+ M+H
Sbjct: 263 FYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
Query: 979 PWIKQHVAIANYVFH 993
PWI Q + H
Sbjct: 323 PWIMQSTKVPQTPLH 337
>BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 101 bits (241), Expect = 2e-20
Identities = 83/255 (32%), Positives = 123/255 (48%), Gaps = 27/255 (10%)
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYEN----EKYFQMVMEKHGAG 817
+EK L D P ++ +EL + + P+IV +VDVYEN K +VME G
Sbjct: 87 QEKFALKMLQDCPKARR-EVELHWRAS-QCPHIVRIVDVYENLYAGRKCLLIVMECLDGG 144
Query: 818 MDLFEFIERR--PRMDEPLLSYIFRQVGQAVEYLHSLNILHRX---XXXXXXXXXXXFHV 872
+LF I+ R E S I + +G+A++YLHS+NI HR +
Sbjct: 145 -ELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAIL 203
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
KL DFG A + + +T T Y +PEVL KY +MWS+G+ +Y+L P
Sbjct: 204 KLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY-DKSCDMWSLGVIMYILLCGYPP 262
Query: 933 F---------SDIEDTIQ-GPLTFPH----LVSEDLEQLLRWMLCKDPANRCTITQLMSH 978
F ++ I+ G FP+ VSE+++ L+R +L +P R TIT+ M+H
Sbjct: 263 FYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
Query: 979 PWIKQHVAIANYVFH 993
PWI Q + H
Sbjct: 323 PWIMQSTKVPQTPLH 337
>BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 101 bits (241), Expect = 2e-20
Identities = 83/255 (32%), Positives = 123/255 (48%), Gaps = 27/255 (10%)
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYEN----EKYFQMVMEKHGAG 817
+EK L D P ++ +EL + + P+IV +VDVYEN K +VME G
Sbjct: 87 QEKFALKMLQDCPKARR-EVELHWRAS-QCPHIVRIVDVYENLYAGRKCLLIVMECLDGG 144
Query: 818 MDLFEFIERR--PRMDEPLLSYIFRQVGQAVEYLHSLNILHRX---XXXXXXXXXXXFHV 872
+LF I+ R E S I + +G+A++YLHS+NI HR +
Sbjct: 145 -ELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAIL 203
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
KL DFG A + + +T T Y +PEVL KY +MWS+G+ +Y+L P
Sbjct: 204 KLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY-DKSCDMWSLGVIMYILLCGYPP 262
Query: 933 F---------SDIEDTIQ-GPLTFPH----LVSEDLEQLLRWMLCKDPANRCTITQLMSH 978
F ++ I+ G FP+ VSE+++ L+R +L +P R TIT+ M+H
Sbjct: 263 FYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
Query: 979 PWIKQHVAIANYVFH 993
PWI Q + H
Sbjct: 323 PWIMQSTKVPQTPLH 337
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 101 bits (241), Expect = 2e-20
Identities = 77/263 (29%), Positives = 125/263 (47%), Gaps = 22/263 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G+G+Y VK AY + K I ++K FL K +P E+ +L L H +I
Sbjct: 18 LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLE-----KFLPREIEILAMLNHCSI 72
Query: 795 VSLVDVYENEK-YFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLN 853
+ +++E +VME G DL E I+ R + E F Q+ A++Y H L+
Sbjct: 73 IKTYEIFETSHGKVYIVMELAVQG-DLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 854 ILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD-----SLFSTFYGTTEYCSPEVLAGNK 908
++HR F++KL DF + +D +L TF G+ Y +PEVL G
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD--IEDTI----QGPLTFP---HLVSEDLEQLLR 959
Y ++WS+G+ LY++ P+ D I+ + + + FP HL E + L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGE-CKDLIY 250
Query: 960 WMLCKDPANRCTITQLMSHPWIK 982
ML D R I +++SH W++
Sbjct: 251 HMLQPDVNRRLHIDEILSHCWMQ 273
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 101 bits (241), Expect = 2e-20
Identities = 77/263 (29%), Positives = 125/263 (47%), Gaps = 22/263 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G+G+Y VK AY + K I ++K FL K +P E+ +L L H +I
Sbjct: 18 LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLE-----KFLPREIEILAMLNHCSI 72
Query: 795 VSLVDVYENEK-YFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLN 853
+ +++E +VME G DL E I+ R + E F Q+ A++Y H L+
Sbjct: 73 IKTYEIFETSHGKVYIVMELAVQG-DLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 854 ILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD-----SLFSTFYGTTEYCSPEVLAGNK 908
++HR F++KL DF + +D +L TF G+ Y +PEVL G
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD--IEDTI----QGPLTFP---HLVSEDLEQLLR 959
Y ++WS+G+ LY++ P+ D I+ + + + FP HL E + L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGE-CKDLIY 250
Query: 960 WMLCKDPANRCTITQLMSHPWIK 982
ML D R I +++SH W++
Sbjct: 251 HMLQPDVNRRLHIDEILSHCWMQ 273
>AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 101 bits (241), Expect = 2e-20
Identities = 83/255 (32%), Positives = 123/255 (48%), Gaps = 27/255 (10%)
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYEN----EKYFQMVMEKHGAG 817
+EK L D P ++ +EL + + P+IV +VDVYEN K +VME G
Sbjct: 87 QEKFALKMLQDCPKARR-EVELHWRAS-QCPHIVRIVDVYENLYAGRKCLLIVMECLDGG 144
Query: 818 MDLFEFIERR--PRMDEPLLSYIFRQVGQAVEYLHSLNILHRX---XXXXXXXXXXXFHV 872
+LF I+ R E S I + +G+A++YLHS+NI HR +
Sbjct: 145 -ELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAIL 203
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
KL DFG A + + +T T Y +PEVL KY +MWS+G+ +Y+L P
Sbjct: 204 KLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY-DKSCDMWSLGVIMYILLCGYPP 262
Query: 933 F---------SDIEDTIQ-GPLTFPH----LVSEDLEQLLRWMLCKDPANRCTITQLMSH 978
F ++ I+ G FP+ VSE+++ L+R +L +P R TIT+ M+H
Sbjct: 263 FYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
Query: 979 PWIKQHVAIANYVFH 993
PWI Q + H
Sbjct: 323 PWIMQSTKVPQTPLH 337
>AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 370
Score = 101 bits (241), Expect = 2e-20
Identities = 83/255 (32%), Positives = 123/255 (48%), Gaps = 27/255 (10%)
Query: 762 KEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNIVSLVDVYEN----EKYFQMVMEKHGAG 817
+EK L D P ++ +EL + + P+IV +VDVYEN K +VME G
Sbjct: 87 QEKFALKMLQDCPKARR-EVELHWRAS-QCPHIVRIVDVYENLYAGRKCLLIVMECLDGG 144
Query: 818 MDLFEFIERR--PRMDEPLLSYIFRQVGQAVEYLHSLNILHRX---XXXXXXXXXXXFHV 872
+LF I+ R E S I + +G+A++YLHS+NI HR +
Sbjct: 145 -ELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAIL 203
Query: 873 KLIDFGSATFMSKDSLFSTFYGTTEYCSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDP 932
KL DFG A + + +T T Y +PEVL KY +MWS+G+ +Y+L P
Sbjct: 204 KLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKY-DKSCDMWSLGVIMYILLCGYPP 262
Query: 933 F---------SDIEDTIQ-GPLTFPH----LVSEDLEQLLRWMLCKDPANRCTITQLMSH 978
F ++ I+ G FP+ VSE+++ L+R +L +P R TIT+ M+H
Sbjct: 263 FYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNH 322
Query: 979 PWIKQHVAIANYVFH 993
PWI Q + H
Sbjct: 323 PWIMQSTKVPQTPLH 337
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 101 bits (241), Expect = 2e-20
Identities = 77/263 (29%), Positives = 125/263 (47%), Gaps = 22/263 (8%)
Query: 735 IGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLTLKHPNI 794
+G+G+Y VK AY + K I ++K FL K +P E+ +L L H +I
Sbjct: 18 LGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLE-----KFLPREIEILAMLNHCSI 72
Query: 795 VSLVDVYENEK-YFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLHSLN 853
+ +++E +VME G DL E I+ R + E F Q+ A++Y H L+
Sbjct: 73 IKTYEIFETSHGKVYIVMELAVQG-DLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131
Query: 854 ILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKD-----SLFSTFYGTTEYCSPEVLAGNK 908
++HR F++KL DF + +D +L TF G+ Y +PEVL G
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191
Query: 909 YAGPELEMWSMGITLYVLTFFVDPFSD--IEDTI----QGPLTFP---HLVSEDLEQLLR 959
Y ++WS+G+ LY++ P+ D I+ + + + FP HL E + L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGE-CKDLIY 250
Query: 960 WMLCKDPANRCTITQLMSHPWIK 982
ML D R I +++SH W++
Sbjct: 251 HMLQPDVNRRLHIDEILSHCWMQ 273
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 100 bits (240), Expect = 3e-20
Identities = 50/158 (31%), Positives = 82/158 (51%), Gaps = 6/158 (3%)
Query: 839 FRQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFGSATFMSKDSLFSTFYGTTEY 898
F+Q+ AV + H NI+HR ++K+ DFG + + L T+ G+ Y
Sbjct: 10 FKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPY 69
Query: 899 CSPEVLAGNKYAGPELEMWSMGITLYVLTFFVDPF--SDIED----TIQGPLTFPHLVSE 952
+PE+ G +Y GP++++WS+G+ LYVL PF S +++ + G P +S
Sbjct: 70 AAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMST 129
Query: 953 DLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANY 990
+ E L+R ML DP R ++ Q+ H W+K A N+
Sbjct: 130 ECEHLIRHMLVLDPNKRLSMEQICKHKWMKLGDADPNF 167
>BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein.
Length = 266
Score = 100 bits (239), Expect = 3e-20
Identities = 67/207 (32%), Positives = 106/207 (51%), Gaps = 15/207 (7%)
Query: 782 ELSLLLTLKHPNIVSLVDVYE--NEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIF 839
E+++L L HPN+V LV+V + NE + MV E G + E +P + E + F
Sbjct: 4 EIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQG-PVMEVPTLKP-LSEDQARFYF 61
Query: 840 RQVGQAVEYLHSLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSLFSTFYGTTEY 898
+ + + +EYLH I+HR H+K+ DFG S F D+L S GT +
Sbjct: 62 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAF 121
Query: 899 CSPEVLAGNK--YAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-PLTFPHL- 949
+PE L+ ++G L++W+MG+TLY F PF D + I+ L FP
Sbjct: 122 MAPESLSETCKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQP 181
Query: 950 -VSEDLEQLLRWMLCKDPANRCTITQL 975
++EDL+ L+ ML K+P +R + ++
Sbjct: 182 DIAEDLKDLITRMLDKNPESRIVVPEI 208
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 98.7 bits (235), Expect = 1e-19
Identities = 77/246 (31%), Positives = 116/246 (47%), Gaps = 15/246 (6%)
Query: 732 LKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLL-TLK 790
LK IGKG YG V +A R+SD K + K+ I + + + E S+LL ++
Sbjct: 38 LKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSI-----LKKKEQSHIMAERSVLLKNVR 92
Query: 791 HPNIVSLVDVYENEKYFQMVMEKHGAGMDLFEFIERRPRMDEPLLSYIFRQVGQAVEYLH 850
HP +V L ++ + V++ G +LF ++R R EP + +V A++YLH
Sbjct: 93 HPFLVGLRYSFQTPEKLYFVLDYVNGG-ELFFHLQRERRFLEPRARFYAAEVASAIDYLH 151
Query: 851 SLNILHRXXXXXXXXXXXXFHVKLIDFG-SATFMSKDSLFSTFYGTTEYCSPEVLAGNKY 909
SLNI++R HV L DFG + + STF GT EY +PEVL Y
Sbjct: 152 SLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPY 211
Query: 910 AGPELEMWSMGITLYVLTFFVDPF--SDI----EDTIQGPLTFPHLVSEDLEQLLRWMLC 963
++ W +G LY + + PF D+ E+ + PL P + LL+ +L
Sbjct: 212 -DRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLH 270
Query: 964 KDPANR 969
KD R
Sbjct: 271 KDQRQR 276
>BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein.
Length = 898
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AY705392-1|AAU10527.1| 921|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
protein.
Length = 921
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL627402-6|CAH71241.1| 590|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 590
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL627402-5|CAH71238.1| 897|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 897
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL627402-4|CAH71237.1| 909|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 909
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL627402-3|CAH71240.1| 926|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 926
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL627402-2|CAH71239.1| 921|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 921
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL603754-6|CAI41638.1| 590|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 590
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL603754-5|CAI41635.1| 926|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 926
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL603754-4|CAI41636.1| 921|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 921
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL603754-3|CAI41637.1| 897|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 897
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL603754-2|CAI41634.1| 909|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 909
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL445239-7|CAI41096.1| 590|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 590
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL445239-6|CAI41093.1| 926|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 926
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL445239-5|CAI41094.1| 921|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 921
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL445239-4|CAI41095.1| 897|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 897
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL445239-3|CAI41092.1| 909|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 909
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
>AL353691-7|CAI42248.1| 590|Homo sapiens
calcium/calmodulin-dependent serine protein kinase
(MAGUK family) protein.
Length = 590
Score = 98.7 bits (235), Expect = 1e-19
Identities = 82/283 (28%), Positives = 126/283 (44%), Gaps = 25/283 (8%)
Query: 729 YVTLKQIGKGAYGCVKMAYRRSDRLLTVTKFILKEKIGPLFLVDGPDGKKVPLELSLLLT 788
Y + IGKG + V+ R K + + G + + E S+
Sbjct: 12 YELCEVIGKGPFSVVRRCINRETGQQFAVKIV---DVAKFTSSPGLSTEDLKREASICHM 68
Query: 789 LKHPNIVSLVDVYENEKYFQMVMEKHGAGMDL-FEFIERRPR---MDEPLLSYIFRQVGQ 844
LKHP+IV L++ Y ++ MV E G DL FE ++R E + S+ RQ+ +
Sbjct: 69 LKHPHIVELLETYSSDGMLYMVFEFMD-GADLCFEIVKRADAGFVYSEAVASHYMRQILE 127
Query: 845 AVEYLHSLNILHRXXX---XXXXXXXXXFHVKLIDFGSATFMSKDSLFSTF-YGTTEYCS 900
A+ Y H NI+HR VKL FG A + + L + GT + +
Sbjct: 128 ALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMA 187
Query: 901 PEVLAGNKYAGPELEMWSMGITLYVLTFFVDPFSD-----IEDTIQG-----PLTFPHLV 950
PEV+ Y P +++W G+ L++L PF E I+G P + H +
Sbjct: 188 PEVVKREPYGKP-VDVWGCGVILFILLSGCLPFYGTKERLFEGIIKGKYKMNPRQWSH-I 245
Query: 951 SEDLEQLLRWMLCKDPANRCTITQLMSHPWIKQHVAIANYVFH 993
SE + L+R ML DPA R T+ + ++HPW+K+ A Y H
Sbjct: 246 SESAKDLVRRMLMLDPAERITVYEALNHPWLKERDRYA-YKIH 287
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.132 0.391
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 169,053,252
Number of Sequences: 224733
Number of extensions: 7214822
Number of successful extensions: 21777
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 975
Number of HSP's successfully gapped in prelim test: 1396
Number of HSP's that attempted gapping in prelim test: 16420
Number of HSP's gapped (non-prelim): 3313
length of query: 1130
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1032
effective length of database: 51,211,004
effective search space: 52849756128
effective search space used: 52849756128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 71 (32.7 bits)
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