Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002587-TA|BGIBMGA002587-PA|IPR000323|Copper type II,
ascorbate-dependent monooxygenase, core, IPR000720|Peptidyl-glycine
alpha-amidating monooxygenase, IPR008977|PHM/PNGase F Fold
(273 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S75038-1|AAB32776.1| 905|Homo sapiens pancreatic peptidylglycin... 176 8e-44
S75037-1|AAB32775.1| 971|Homo sapiens pancreatic peptidylglycin... 176 8e-44
M37721-1|AAA36414.1| 974|Homo sapiens peptidylglycine alpha-ami... 176 8e-44
BT007419-1|AAP36087.1| 866|Homo sapiens peptidylglycine alpha-a... 176 8e-44
BC018127-1|AAH18127.1| 866|Homo sapiens peptidylglycine alpha-a... 176 8e-44
AF010472-1|AAD01439.1| 825|Homo sapiens alpha-amidating monooxy... 176 8e-44
AB095007-1|BAC22594.1| 973|Homo sapiens peptidylglycine alpha-a... 176 8e-44
Y00096-1|CAA68285.1| 603|Homo sapiens protein ( Human mRNA for ... 73 1e-12
X13256-1|CAA31632.1| 603|Homo sapiens dopamine beta-hydroxylase... 73 1e-12
X13255-1|CAA31631.1| 603|Homo sapiens dopamine beta-hydroxylase... 73 1e-12
BC017174-1|AAH17174.1| 603|Homo sapiens DBH protein protein. 73 1e-12
AL365494-1|CAI13354.2| 617|Homo sapiens dopamine beta-hydroxyla... 73 1e-12
BC018756-1|AAH18756.1| 613|Homo sapiens monooxygenase, DBH-like... 66 1e-10
AY359094-1|AAQ89452.1| 613|Homo sapiens dopamine-oxygenase prot... 66 1e-10
AY007239-1|AAG09636.1| 545|Homo sapiens monooxygenase X protein. 66 1e-10
AL357034-4|CAI15718.1| 613|Homo sapiens monooxygenase, DBH-like... 66 1e-10
AL357034-1|CAI15715.1| 545|Homo sapiens monooxygenase, DBH-like... 66 1e-10
AL023578-2|CAI19938.1| 613|Homo sapiens monooxygenase, DBH-like... 66 1e-10
AL023578-1|CAI19937.1| 545|Homo sapiens monooxygenase, DBH-like... 66 1e-10
AK074879-1|BAC11263.1| 544|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AL080058-1|CAB45692.1| 335|Homo sapiens hypothetical protein pr... 48 5e-05
>S75038-1|AAB32776.1| 905|Homo sapiens pancreatic peptidylglycine
alpha-amidating monooxygenase protein.
Length = 905
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>S75037-1|AAB32775.1| 971|Homo sapiens pancreatic peptidylglycine
alpha-amidating monooxygenase protein.
Length = 971
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>M37721-1|AAA36414.1| 974|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 974
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>BT007419-1|AAP36087.1| 866|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 866
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>BC018127-1|AAH18127.1| 866|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 866
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>AF010472-1|AAD01439.1| 825|Homo sapiens alpha-amidating
monooxygenase protein.
Length = 825
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 36 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 82
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 83 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 142
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 143 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 197
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 198 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 257
>AB095007-1|BAC22594.1| 973|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 973
Score = 176 bits (428), Expect = 8e-44
Identities = 100/240 (41%), Positives = 134/240 (55%), Gaps = 23/240 (9%)
Query: 1 MHTAHHMLLYGCSEPGSNDSVWNCGEMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLH 60
M T HHMLL+GC+ P S S W C E C + I+YAWAR+AP
Sbjct: 98 MDTVHHMLLFGCNMPSSTGSYWFCDE-------------GTCTDKANILYAWARNAPPTR 144
Query: 61 LPKDVGFLVGQGSPIKYLVLQVHY--MHRFPKGHTDNSGVFLKYTKAHMPRQAGVILLGT 118
LPK VGF VG + KY VLQVHY + F + D SGV L T+ P AG+ L+ +
Sbjct: 145 LPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMS 204
Query: 119 SGIIMP--NMVEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKDGDEWTLLG 176
++P V + + +C ++ +H FA+R HTH LG +VSGY V RN +WTL+G
Sbjct: 205 VDTVIPAGEKVVNSDISCHY-KNYPMHVFAYRVHTHHLGKVVSGYRV-RN---GQWTLIG 259
Query: 177 KKNPQLPQMFYPTENRDPIKKNDVLAARCTM-NNSHEYVVKIGATNQDEMCNFYLMYWVE 235
+++PQLPQ FYP + + D+LAARC IG T+ DEMCN Y+MY++E
Sbjct: 260 RQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME 319
>Y00096-1|CAA68285.1| 603|Homo sapiens protein ( Human mRNA for
dopamine beta-hydroxylase (EC 1.14.17.1). ).
Length = 603
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 48 IVYAWARDAPSLHLPKDVGFLVGQGSPIKYLVLQVHYMHRFP-KGHTDNSGVFLKYTKAH 106
++ AWA A + + P++ G G +YL L+VHY + +G D+SG+ L YT
Sbjct: 284 VLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKL 343
Query: 107 MPRQAGVILLGTSGIIMPNM-VEHMETACTMT---EDKT---------IHPFAFRTHTHS 153
AG++ LG + P M + ETA +T DK IH FA + HTH
Sbjct: 344 RRFNAGIMELGL--VYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHL 401
Query: 154 LGTLVSGYVVHRNKDGDEWTLLGKKNPQLP--QMFYPTENRDPIKKNDVLAARCTMNNSH 211
G V +V +DG EW ++ + N P Q + + DVL CT N
Sbjct: 402 TGRKVVTVLV---RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTED 458
Query: 212 EYVVKIGATN-QDEMCNFYLMYWVENDTPL 240
+ +G +EMC Y+ Y+ + L
Sbjct: 459 RELATVGGFGILEEMCVNYVHYYPQTQLEL 488
>X13256-1|CAA31632.1| 603|Homo sapiens dopamine beta-hydroxylase
preprotein (AA -25 to 578) protein.
Length = 603
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 48 IVYAWARDAPSLHLPKDVGFLVGQGSPIKYLVLQVHYMHRFP-KGHTDNSGVFLKYTKAH 106
++ AWA A + + P++ G G +YL L+VHY + +G D+SG+ L YT
Sbjct: 284 VLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKL 343
Query: 107 MPRQAGVILLGTSGIIMPNM-VEHMETACTMT---EDKT---------IHPFAFRTHTHS 153
AG++ LG + P M + ETA +T DK IH FA + HTH
Sbjct: 344 RRFNAGIMELGL--VYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHL 401
Query: 154 LGTLVSGYVVHRNKDGDEWTLLGKKNPQLP--QMFYPTENRDPIKKNDVLAARCTMNNSH 211
G V +V +DG EW ++ + N P Q + + DVL CT N
Sbjct: 402 TGRKVVTVLV---RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTED 458
Query: 212 EYVVKIGATN-QDEMCNFYLMYWVENDTPL 240
+ +G +EMC Y+ Y+ + L
Sbjct: 459 RELATVGGFGILEEMCVNYVHYYPQTQLEL 488
>X13255-1|CAA31631.1| 603|Homo sapiens dopamine beta-hydroxylase
preprotein (AA -25 to 578) protein.
Length = 603
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 48 IVYAWARDAPSLHLPKDVGFLVGQGSPIKYLVLQVHYMHRFP-KGHTDNSGVFLKYTKAH 106
++ AWA A + + P++ G G +YL L+VHY + +G D+SG+ L YT
Sbjct: 284 VLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKL 343
Query: 107 MPRQAGVILLGTSGIIMPNM-VEHMETACTMT---EDKT---------IHPFAFRTHTHS 153
AG++ LG + P M + ETA +T DK IH FA + HTH
Sbjct: 344 RRFNAGIMELGL--VYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHL 401
Query: 154 LGTLVSGYVVHRNKDGDEWTLLGKKNPQLP--QMFYPTENRDPIKKNDVLAARCTMNNSH 211
G V +V +DG EW ++ + N P Q + + DVL CT N
Sbjct: 402 TGRKVVTVLV---RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTED 458
Query: 212 EYVVKIGATN-QDEMCNFYLMYWVENDTPL 240
+ +G +EMC Y+ Y+ + L
Sbjct: 459 RELATVGGFGILEEMCVNYVHYYPQTQLEL 488
>BC017174-1|AAH17174.1| 603|Homo sapiens DBH protein protein.
Length = 603
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 48 IVYAWARDAPSLHLPKDVGFLVGQGSPIKYLVLQVHYMHRFP-KGHTDNSGVFLKYTKAH 106
++ AWA A + + P++ G G +YL L+VHY + +G D+SG+ L YT
Sbjct: 284 VLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKL 343
Query: 107 MPRQAGVILLGTSGIIMPNM-VEHMETACTMT---EDKT---------IHPFAFRTHTHS 153
AG++ LG + P M + ETA +T DK IH FA + HTH
Sbjct: 344 RRFNAGIMELGL--VYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHL 401
Query: 154 LGTLVSGYVVHRNKDGDEWTLLGKKNPQLP--QMFYPTENRDPIKKNDVLAARCTMNNSH 211
G V +V +DG EW ++ + N P Q + + DVL CT N
Sbjct: 402 TGRKVVTVLV---RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTED 458
Query: 212 EYVVKIGATN-QDEMCNFYLMYWVENDTPL 240
+ +G +EMC Y+ Y+ + L
Sbjct: 459 RELATVGGFGILEEMCVNYVHYYPQTQLEL 488
>AL365494-1|CAI13354.2| 617|Homo sapiens dopamine beta-hydroxylase
(dopamine beta-monooxygenase) protein.
Length = 617
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/210 (29%), Positives = 93/210 (44%), Gaps = 22/210 (10%)
Query: 48 IVYAWARDAPSLHLPKDVGFLVGQGSPIKYLVLQVHYMHRFP-KGHTDNSGVFLKYTKAH 106
++ AWA A + + P++ G G +YL L+VHY + +G D+SG+ L YT
Sbjct: 298 VLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHYHNPLVIEGRNDSSGIRLYYTAKL 357
Query: 107 MPRQAGVILLGTSGIIMPNM-VEHMETACTMT---EDKT---------IHPFAFRTHTHS 153
AG++ LG + P M + ETA +T DK IH FA + HTH
Sbjct: 358 RRFNAGIMELGL--VYTPVMAIPPRETAFILTGYCTDKCTQLALPPSGIHIFASQLHTHL 415
Query: 154 LGTLVSGYVVHRNKDGDEWTLLGKKNPQLP--QMFYPTENRDPIKKNDVLAARCTMNNSH 211
G V +V +DG EW ++ + N P Q + + DVL CT N
Sbjct: 416 TGRKVVTVLV---RDGREWEIVNQDNHYSPHFQEIRMLKKVVSVHPGDVLITSCTYNTED 472
Query: 212 EYVVKIGATN-QDEMCNFYLMYWVENDTPL 240
+ +G +EMC Y+ Y+ + L
Sbjct: 473 RELATVGGFGILEEMCVNYVHYYPQTQLEL 502
>BC018756-1|AAH18756.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 235 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 287
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 288 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 347
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 348 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 404
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 405 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 464
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 465 CLSYLLYY 472
>AY359094-1|AAQ89452.1| 613|Homo sapiens dopamine-oxygenase
protein.
Length = 613
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 235 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 287
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 288 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 347
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 348 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 404
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 405 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 464
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 465 CLSYLLYY 472
>AY007239-1|AAG09636.1| 545|Homo sapiens monooxygenase X protein.
Length = 545
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 167 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 219
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 220 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 279
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 280 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 336
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 337 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 396
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 397 CLSYLLYY 404
>AL357034-4|CAI15718.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 235 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 287
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 288 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 347
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 348 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 404
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 405 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 464
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 465 CLSYLLYY 472
>AL357034-1|CAI15715.1| 545|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 545
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 167 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 219
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 220 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 279
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 280 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 336
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 337 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 396
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 397 CLSYLLYY 404
>AL023578-2|CAI19938.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 235 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 287
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 288 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 347
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 348 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 404
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 405 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 464
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 465 CLSYLLYY 472
>AL023578-1|CAI19937.1| 545|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 545
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 167 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 219
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 220 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 279
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 280 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 336
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 337 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 396
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 397 CLSYLLYY 404
>AK074879-1|BAC11263.1| 544|Homo sapiens protein ( Homo sapiens
cDNA FLJ90398 fis, clone NT2RP2005883, weakly similar to
DOPAMINE-BETA-MONOOXYGENASE PRECURSOR (EC 1.14.17.1). ).
Length = 544
Score = 66.1 bits (154), Expect = 1e-10
Identities = 72/248 (29%), Positives = 100/248 (40%), Gaps = 29/248 (11%)
Query: 5 HHMLLYGCSEPGSNDSVWNCG-EMQRNVIDEIYSTASPCRSGSQIVYAWARDAPSLHLPK 63
HH+LLY CS NDSV G E + + + T C + +++AWA P
Sbjct: 166 HHILLYQCSN-NFNDSVLESGHECYHPNMPDAFLT---CET---VIFAWAIGGEGFSYPP 218
Query: 64 DVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG----T 118
VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 219 HVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSL 278
Query: 119 SGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRNKD 168
I P M +E +E A + IH FA H H G G + +
Sbjct: 279 FHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHFRK 335
Query: 169 GDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQDEM 225
G E LL + Q F + I D L C N + G + + EM
Sbjct: 336 GKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDNLITECRYNTKDRAEMTWGGLSTRSEM 395
Query: 226 CNFYLMYW 233
C YL+Y+
Sbjct: 396 CLSYLLYY 403
>AL080058-1|CAB45692.1| 335|Homo sapiens hypothetical protein
protein.
Length = 335
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/190 (28%), Positives = 74/190 (38%), Gaps = 21/190 (11%)
Query: 62 PKDVGFLVGQGSPIKYLVLQVHYMH-RFPKGHTDNSGVFLKYTKAHMPRQAGVILLG--- 117
P VG +G Y++L+VHY + + +G DNSG+ L YT AGVI G
Sbjct: 8 PPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWV 67
Query: 118 -TSGIIMPNM----------VEHMETACTMTEDKTIHPFAFRTHTHSLGTLVSGYVVHRN 166
I P M +E +E A + IH FA H H G G +
Sbjct: 68 SLFHTIPPGMPEFQSEGHCTLECLEEALEAEKPSGIHVFAVLLHAHLAG---RGIRLRHF 124
Query: 167 KDGDEWTLLGKKN--PQLPQMFYPTENRDPIKKNDVLAARCTMNNSHEYVVKIGA-TNQD 223
+ G E LL + Q F + I D L C N + G + +
Sbjct: 125 RKGKEMKLLAYDDDFDFNFQEFQYLKEEQTILPGDYLITECRYNTKDRAEMTWGGLSTRS 184
Query: 224 EMCNFYLMYW 233
EMC YL+Y+
Sbjct: 185 EMCLSYLLYY 194
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.436
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 48,800,234
Number of Sequences: 224733
Number of extensions: 2157668
Number of successful extensions: 3249
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3150
Number of HSP's gapped (non-prelim): 21
length of query: 273
length of database: 73,234,838
effective HSP length: 89
effective length of query: 184
effective length of database: 53,233,601
effective search space: 9794982584
effective search space used: 9794982584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 64 (29.9 bits)
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