Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002527-TA|BGIBMGA002527-PA|IPR001548|Peptidase M2,
peptidyl-dipeptidase A, IPR006025|Peptidase M, neutral zinc
metallopeptidases, zinc-binding site
(649 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X16295-1|CAA34362.1| 732|Homo sapiens peptidyl dipeptidase I p... 586 e-167
M26657-1|AAA60611.1| 732|Homo sapiens DCP1 protein. 586 e-167
J04144-1|AAA51684.1| 1306|Homo sapiens DCP1 protein. 586 e-167
BC036375-1|AAH36375.1| 739|Homo sapiens angiotensin I convertin... 586 e-167
AY436326-1|AAR03504.1| 1306|Homo sapiens angiotensin I convertin... 586 e-167
AF118569-2|AAD28561.1| 732|Homo sapiens angiotensin I convertin... 586 e-167
AF118569-1|AAD28560.1| 1306|Homo sapiens angiotensin I convertin... 586 e-167
AB208971-1|BAD92208.1| 1247|Homo sapiens angiotensin I convertin... 586 e-167
M26658-1|AAA60612.1| 694|Homo sapiens DCP1 protein. 580 e-165
BC048094-1|AAH48094.2| 805|Homo sapiens angiotensin I convertin... 433 e-120
BC039902-1|AAH39902.1| 805|Homo sapiens angiotensin I convertin... 433 e-120
AY623811-1|AAT45083.1| 805|Homo sapiens angiotensin converting ... 433 e-120
AY217547-1|AAO25651.1| 805|Homo sapiens angiotensin I convertin... 433 e-120
AL110224-1|CAB53682.1| 804|Homo sapiens hypothetical protein pr... 433 e-120
AF291820-1|AAF99721.1| 805|Homo sapiens ACE-related carboxypept... 433 e-120
AF241254-1|AAF78220.1| 805|Homo sapiens angiotensin converting ... 433 e-120
AB193260-1|BAD99267.1| 805|Homo sapiens angiotensin-converting ... 433 e-120
AB193259-1|BAD99266.1| 805|Homo sapiens angiotensin-converting ... 433 e-120
AB046569-1|BAB40370.1| 805|Homo sapiens ACE2 protein. 433 e-120
AY358714-1|AAQ89076.1| 555|Homo sapiens ACE2 protein. 381 e-105
S81361-1|AAD14360.1| 135|Homo sapiens angiotensin I-converting ... 122 4e-27
AY999974-1|ABA39230.1| 47|Homo sapiens angiotensin I convertin... 53 3e-06
DQ457018-1|ABF00475.1| 42|Homo sapiens angiotensin I convertin... 48 1e-04
DQ458794-1|ABE96829.1| 41|Homo sapiens angiotensin I convertin... 43 0.003
AY999973-1|ABA39229.1| 32|Homo sapiens angiotensin I convertin... 38 0.11
AY999972-1|ABA39228.1| 32|Homo sapiens angiotensin I convertin... 38 0.11
AK131280-1|BAD18455.1| 974|Homo sapiens protein ( Homo sapiens ... 33 2.4
AF068293-1|AAF65182.1| 176|Homo sapiens HDCMB07P protein. 31 9.6
>X16295-1|CAA34362.1| 732|Homo sapiens peptidyl dipeptidase I
protein.
Length = 732
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 78 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 137
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 138 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 194
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 195 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 254
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 255 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 314
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 315 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 374
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 375 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 434
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 435 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 494
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 495 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 554
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 555 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 608
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 609 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
>M26657-1|AAA60611.1| 732|Homo sapiens DCP1 protein.
Length = 732
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 78 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 137
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 138 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 194
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 195 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 254
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 255 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 314
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 315 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 374
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 375 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 434
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 435 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 494
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 495 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 554
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 555 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 608
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 609 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
>J04144-1|AAA51684.1| 1306|Homo sapiens DCP1 protein.
Length = 1306
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 652 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 711
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 712 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 768
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 769 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 828
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 829 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 888
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 889 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 948
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 949 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 1008
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 1009 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 1068
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 1069 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 1128
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 1129 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 1182
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 1183 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221
Score = 573 bits (1414), Expect = e-163
Identities = 264/583 (45%), Positives = 373/583 (63%), Gaps = 12/583 (2%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYW----KETMSY 95
+ ++ + ++ + ASW ++TN+T N ++ + +L ++ E E W KE
Sbjct: 49 FAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAAL-LSQEFAEAWGQKAKELYEP 107
Query: 96 LWHEFEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDL 155
+W F DP L+R+ LG++ LP Q+ +++M Y+ A +C N C
Sbjct: 108 IWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATC-W 166
Query: 156 HVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEW 215
++P++TNI A+S L + W WH AAG P K + ++ + NEA K +G+ +
Sbjct: 167 SLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY 226
Query: 216 WLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIW 275
W S Y + ED L+ Q++PLY +HA+VR L +YG+ + +GPIPAHLLG++W
Sbjct: 227 WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMW 286
Query: 276 AQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERS 335
AQ+W N+ P+PDK ++DVT+ ++ Q + A MF+ AEEFFTSL+LSPMP FWE S
Sbjct: 287 AQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGS 346
Query: 336 ILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPV 395
+LEKP DGRE+VCHASAWDF++ +DFRI+QCT +T T HHEMGHIQYYLQYKD PV
Sbjct: 347 MLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPV 406
Query: 396 IYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLP 455
R GANPGFHEA+GDV+ALSV+TP+HL +GLL+ D ES+IN L KM L+KI FLP
Sbjct: 407 SLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLP 466
Query: 456 FGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVE 515
FGYL+D +R+GVF G T YN +W LR QG+ PP R+E FD AK+H+
Sbjct: 467 FGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTP 526
Query: 516 YMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKP 575
Y+RY++S+++QFQFH +LC+ AG L CDIY ST AG L K+LQ GSS+P
Sbjct: 527 YIRYFVSFVLQFQFHEALCKEAGYEGP------LHQCDIYRSTKAGAKLRKVLQAGSSRP 580
Query: 576 WPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
W + ++ + G +DA +L+YFQP+ WL+ +N++NGE +GW
Sbjct: 581 WQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
>BC036375-1|AAH36375.1| 739|Homo sapiens angiotensin I converting
enzyme (peptidyl-dipeptidase A) 1 protein.
Length = 739
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 78 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 137
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 138 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 194
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 195 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 254
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 255 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 314
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 315 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 374
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 375 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 434
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 435 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 494
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 495 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 554
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 555 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 608
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 609 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
>AY436326-1|AAR03504.1| 1306|Homo sapiens angiotensin I converting
enzyme (peptidyl-dipeptidase A) 1 protein.
Length = 1306
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 652 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 711
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 712 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 768
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 769 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 828
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 829 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 888
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 889 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 948
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 949 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 1008
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 1009 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 1068
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 1069 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 1128
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 1129 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 1182
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 1183 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221
Score = 573 bits (1414), Expect = e-163
Identities = 264/583 (45%), Positives = 373/583 (63%), Gaps = 12/583 (2%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYW----KETMSY 95
+ ++ + ++ + ASW ++TN+T N ++ + +L ++ E E W KE
Sbjct: 49 FAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAAL-LSQEFAEAWGQKAKELYEP 107
Query: 96 LWHEFEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDL 155
+W F DP L+R+ LG++ LP Q+ +++M Y+ A +C N C
Sbjct: 108 IWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATC-W 166
Query: 156 HVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEW 215
++P++TNI A+S L + W WH AAG P K + ++ + NEA K +G+ +
Sbjct: 167 SLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY 226
Query: 216 WLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIW 275
W S Y + ED L+ Q++PLY +HA+VR L +YG+ + +GPIPAHLLG++W
Sbjct: 227 WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMW 286
Query: 276 AQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERS 335
AQ+W N+ P+PDK ++DVT+ ++ Q + A MF+ AEEFFTSL+LSPMP FWE S
Sbjct: 287 AQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGS 346
Query: 336 ILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPV 395
+LEKP DGRE+VCHASAWDF++ +DFRI+QCT +T T HHEMGHIQYYLQYKD PV
Sbjct: 347 MLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPV 406
Query: 396 IYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLP 455
R GANPGFHEA+GDV+ALSV+TP+HL +GLL+ D ES+IN L KM L+KI FLP
Sbjct: 407 SLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLP 466
Query: 456 FGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVE 515
FGYL+D +R+GVF G T YN +W LR QG+ PP R+E FD AK+H+
Sbjct: 467 FGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTP 526
Query: 516 YMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKP 575
Y+RY++S+++QFQFH +LC+ AG L CDIY ST AG L K+LQ GSS+P
Sbjct: 527 YIRYFVSFVLQFQFHEALCKEAGYEGP------LHQCDIYRSTKAGAKLRKVLQAGSSRP 580
Query: 576 WPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
W + ++ + G +DA +L+YFQP+ WL+ +N++NGE +GW
Sbjct: 581 WQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
>AF118569-2|AAD28561.1| 732|Homo sapiens angiotensin I converting
enzyme precursor protein.
Length = 732
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 78 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 137
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 138 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 194
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 195 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 254
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 255 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 314
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 315 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 374
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 375 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 434
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 435 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 494
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 495 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 554
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 555 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 608
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 609 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 647
>AF118569-1|AAD28560.1| 1306|Homo sapiens angiotensin I converting
enzyme precursor protein.
Length = 1306
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 652 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 711
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 712 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 768
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 769 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 828
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 829 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 888
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 889 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 948
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 949 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 1008
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 1009 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 1068
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 1069 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 1128
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 1129 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 1182
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 1183 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1221
Score = 573 bits (1414), Expect = e-163
Identities = 264/583 (45%), Positives = 373/583 (63%), Gaps = 12/583 (2%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYW----KETMSY 95
+ ++ + ++ + ASW ++TN+T N ++ + +L ++ E E W KE
Sbjct: 49 FAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAAL-LSQEFAEAWGQKAKELYEP 107
Query: 96 LWHEFEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDL 155
+W F DP L+R+ LG++ LP Q+ +++M Y+ A +C N C
Sbjct: 108 IWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATC-W 166
Query: 156 HVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEW 215
++P++TNI A+S L + W WH AAG P K + ++ + NEA K +G+ +
Sbjct: 167 SLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY 226
Query: 216 WLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIW 275
W S Y + ED L+ Q++PLY +HA+VR L +YG+ + +GPIPAHLLG++W
Sbjct: 227 WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMW 286
Query: 276 AQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERS 335
AQ+W N+ P+PDK ++DVT+ ++ Q + A MF+ AEEFFTSL+LSPMP FWE S
Sbjct: 287 AQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGS 346
Query: 336 ILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPV 395
+LEKP DGRE+VCHASAWDF++ +DFRI+QCT +T T HHEMGHIQYYLQYKD PV
Sbjct: 347 MLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPV 406
Query: 396 IYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLP 455
R GANPGFHEA+GDV+ALSV+TP+HL +GLL+ D ES+IN L KM L+KI FLP
Sbjct: 407 SLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLP 466
Query: 456 FGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVE 515
FGYL+D +R+GVF G T YN +W LR QG+ PP R+E FD AK+H+
Sbjct: 467 FGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTP 526
Query: 516 YMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKP 575
Y+RY++S+++QFQFH +LC+ AG L CDIY ST AG L K+LQ GSS+P
Sbjct: 527 YIRYFVSFVLQFQFHEALCKEAGYEGP------LHQCDIYRSTKAGAKLRKVLQAGSSRP 580
Query: 576 WPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
W + ++ + G +DA +L+YFQP+ WL+ +N++NGE +GW
Sbjct: 581 WQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 623
>AB208971-1|BAD92208.1| 1247|Homo sapiens angiotensin I converting
enzyme isoform 1 precursor variant protein.
Length = 1247
Score = 586 bits (1447), Expect = e-167
Identities = 271/579 (46%), Positives = 377/579 (65%), Gaps = 9/579 (1%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
+V D + + N+ A+W+Y TN+T + LLQ ++++A+ T +Y + + ++
Sbjct: 660 FVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQ 719
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +KR+ KK +L +ALP + + M++TY+ AT+C N C L +EP
Sbjct: 720 LQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEP 776
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
++TN+ ATS E+L + W W AG + +YV++ N+AA+LNGY + W S
Sbjct: 777 DLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSM 836
Query: 220 YEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTW 279
YE E L+ +++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW
Sbjct: 837 YETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTW 896
Query: 280 GNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEK 339
N+ P+P +D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEK
Sbjct: 897 SNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEK 956
Query: 340 PTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRA 399
PTDGRE+VCHASAWDF++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R
Sbjct: 957 PTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALRE 1016
Query: 400 GANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYL 459
GANPGFHEA+GDV+ALSV+TPKHL + LL E +IN L KM LDKI F+PF YL
Sbjct: 1017 GANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYL 1076
Query: 460 LDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRY 519
+D +R+ VF G+ T ++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY
Sbjct: 1077 VDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRY 1136
Query: 520 YISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDA 579
++S+IIQFQFH +LCQ AG + L CDIY S AG L ++LG S+PWP+A
Sbjct: 1137 FVSFIIQFQFHEALCQAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEA 1190
Query: 580 MEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
M+ ITGQ M AS +L YF+PL DWL+ ENE +GE +GW
Sbjct: 1191 MQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGW 1229
Score = 573 bits (1414), Expect = e-163
Identities = 264/583 (45%), Positives = 373/583 (63%), Gaps = 12/583 (2%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYW----KETMSY 95
+ ++ + ++ + ASW ++TN+T N ++ + +L ++ E E W KE
Sbjct: 57 FAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAAL-LSQEFAEAWGQKAKELYEP 115
Query: 96 LWHEFEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDL 155
+W F DP L+R+ LG++ LP Q+ +++M Y+ A +C N C
Sbjct: 116 IWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATC-W 174
Query: 156 HVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEW 215
++P++TNI A+S L + W WH AAG P K + ++ + NEA K +G+ +
Sbjct: 175 SLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAY 234
Query: 216 WLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIW 275
W S Y + ED L+ Q++PLY +HA+VR L +YG+ + +GPIPAHLLG++W
Sbjct: 235 WRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMW 294
Query: 276 AQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERS 335
AQ+W N+ P+PDK ++DVT+ ++ Q + A MF+ AEEFFTSL+LSPMP FWE S
Sbjct: 295 AQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGS 354
Query: 336 ILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPV 395
+LEKP DGRE+VCHASAWDF++ +DFRI+QCT +T T HHEMGHIQYYLQYKD PV
Sbjct: 355 MLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPV 414
Query: 396 IYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLP 455
R GANPGFHEA+GDV+ALSV+TP+HL +GLL+ D ES+IN L KM L+KI FLP
Sbjct: 415 SLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLP 474
Query: 456 FGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVE 515
FGYL+D +R+GVF G T YN +W LR QG+ PP R+E FD AK+H+
Sbjct: 475 FGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTP 534
Query: 516 YMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKP 575
Y+RY++S+++QFQFH +LC+ AG L CDIY ST AG L K+LQ GSS+P
Sbjct: 535 YIRYFVSFVLQFQFHEALCKEAGYEGP------LHQCDIYRSTKAGAKLRKVLQAGSSRP 588
Query: 576 WPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
W + ++ + G +DA +L+YFQP+ WL+ +N++NGE +GW
Sbjct: 589 WQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGW 631
>M26658-1|AAA60612.1| 694|Homo sapiens DCP1 protein.
Length = 694
Score = 580 bits (1433), Expect = e-165
Identities = 269/564 (47%), Positives = 371/564 (65%), Gaps = 9/564 (1%)
Query: 55 KTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHEFEDPDLKRMFKKYTE 114
K IA+ +Y TN+T + LLQ ++++A+ T +Y + + ++ ++ +KR+ KK +
Sbjct: 55 KPIATKNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQD 114
Query: 115 LGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEPEITNIFATSSDAEEL 174
L +ALP + + M++TY+ AT+C N C L +EP++TN+ ATS E+L
Sbjct: 115 LERAALPAQELEEYNKILLDMETTYSVATVCHPNG--SC-LQLEPDLTNVMATSRKYEDL 171
Query: 175 KYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSEYEATDSEDQFAALWA 234
+ W W AG + +YV++ N+AA+LNGY + W S YE E L+
Sbjct: 172 LWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQ 231
Query: 235 QIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAHLLGNIWAQTWGNVEKFTRPYPDKTD 294
+++PLY +HAYVR L YG + + +GPIPAHLLGN+WAQTW N+ P+P
Sbjct: 232 ELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPS 291
Query: 295 IDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPELFWERSILEKPTDGREMVCHASAWD 354
+D T A++ Q +T +MFK A++FFTSL L P+P FW +S+LEKPTDGRE+VCHASAWD
Sbjct: 292 MDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWD 351
Query: 355 FFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQYKDQPVIYRAGANPGFHEAVGDVIA 414
F++G+DFRI+QCTT+ HHEMGHIQY++QYKD PV R GANPGFHEA+GDV+A
Sbjct: 352 FYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLA 411
Query: 415 LSVATPKHLRVMGLLEDGPEDLESNINQLYKMGLDKIVFLPFGYLLDLFRYGVFRGTTTV 474
LSV+TPKHL + LL E +IN L KM LDKI F+PF YL+D +R+ VF G+ T
Sbjct: 412 LSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITK 471
Query: 475 DDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKYHIAADVEYMRYYISYIIQFQFHRSLC 534
++YN +W LR QG+ PP PR++ DFDP AK+HI + V Y+RY++S+IIQFQFH +LC
Sbjct: 472 ENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALC 531
Query: 535 QLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKMLQLGSSKPWPDAMEAITGQRFMDASGV 594
Q AG + L CDIY S AG L ++LG S+PWP+AM+ ITGQ M AS +
Sbjct: 532 QAAGH------TGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAM 585
Query: 595 LEYFQPLYDWLKAENERNGEFVGW 618
L YF+PL DWL+ ENE +GE +GW
Sbjct: 586 LSYFKPLLDWLRTENELHGEKLGW 609
>BC048094-1|AAH48094.2| 805|Homo sapiens angiotensin I converting
enzyme (peptidyl-dipeptidase A) 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>BC039902-1|AAH39902.1| 805|Homo sapiens angiotensin I converting
enzyme (peptidyl-dipeptidase A) 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AY623811-1|AAT45083.1| 805|Homo sapiens angiotensin converting
enzyme 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AY217547-1|AAO25651.1| 805|Homo sapiens angiotensin I converting
enzyme (peptidyl-dipeptidase A) 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AL110224-1|CAB53682.1| 804|Homo sapiens hypothetical protein
protein.
Length = 804
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 27 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 86
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 87 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 145
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 146 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 205
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 206 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 264
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 265 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 324
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 325 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 383
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 384 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 443
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 444 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 503
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 504 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 557
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 558 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 605
>AF291820-1|AAF99721.1| 805|Homo sapiens ACE-related
carboxypeptidase ACE2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AF241254-1|AAF78220.1| 805|Homo sapiens angiotensin converting
enzyme-like protein protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AB193260-1|BAD99267.1| 805|Homo sapiens angiotensin-converting
enzyme 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AB193259-1|BAD99266.1| 805|Homo sapiens angiotensin-converting
enzyme 2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AB046569-1|BAB40370.1| 805|Homo sapiens ACE2 protein.
Length = 805
Score = 433 bits (1066), Expect = e-120
Identities = 224/590 (37%), Positives = 333/590 (56%), Gaps = 22/590 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALGKML 568
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L ML
Sbjct: 505 HVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKLFNML 558
Query: 569 QLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENERNGEFVGW 618
+LG S+PW A+E + G + M+ +L YF+PL+ WLK +N+ + FVGW
Sbjct: 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW 606
>AY358714-1|AAQ89076.1| 555|Homo sapiens ACE2 protein.
Length = 555
Score = 381 bits (937), Expect = e-105
Identities = 200/536 (37%), Positives = 297/536 (55%), Gaps = 20/536 (3%)
Query: 40 YVRTLDEQTSRLRNKKTIASWDYETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHE 99
++ + + L + ++ASW+Y TN+T N Q + + ++ KE Y E
Sbjct: 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE 87
Query: 100 FEDPDLKRMFKKYTELGTSALPEDLNQRLIVAINSMQSTYAKATICDYNNRTKCDLHVEP 159
++ +K + + G+S L ED ++RL +N+M + Y+ +C+ +N +C L +EP
Sbjct: 88 IQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQEC-LLLEP 146
Query: 160 EITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLNGYDTVAEWWLSE 219
+ I A S D E + W W G + + EYV ++NE A+ N Y+ ++W +
Sbjct: 147 GLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGD 206
Query: 220 YEATDSE----------DQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIPAH 269
YE + + + +IKPLYE +HAYVR L Y + P G +PAH
Sbjct: 207 YEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI-GCLPAH 265
Query: 270 LLGNIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQNYTALKMFKTAEEFFTSLDLSPMPE 329
LLG++W + W N+ T P+ K +IDVT A++ Q + A ++FK AE+FF S+ L M +
Sbjct: 266 LLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQ 325
Query: 330 LFWERSILEKPTDGREMVCHASAWDFFDGEDFRIRQCTTITDAFFKTTHHEMGHIQYYLQ 389
FWE S+L P + ++ VCH +AWD G DFRI CT +T F T HHEMGHIQY +
Sbjct: 326 GFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMGHIQYDMA 384
Query: 390 YKDQPVIYRAGANPGFHEAVGDVIALSVATPKHLRVMGLLE-DGPEDLESNINQLYKMGL 448
Y QP + R GAN GFHEAVG++++LS ATPKHL+ +GLL D ED E+ IN L K L
Sbjct: 385 YAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQAL 444
Query: 449 DKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQLRESLQGVEPPAPRSEADFDPAAKY 508
+ LPF Y+L+ +R+ VF+G D + +W+++ + GV P P E DPA+ +
Sbjct: 445 TIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLF 504
Query: 509 HIAADVEYMRYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNAL 564
H++ D ++RYY + QFQF +LCQ A L CDI NST AG L
Sbjct: 505 HVSDDYSFIRYYTRTLYQFQFQEALCQAAKHEGP------LHKCDISNSTEAGQKL 554
>S81361-1|AAD14360.1| 135|Homo sapiens angiotensin I-converting
enzyme protein.
Length = 135
Score = 122 bits (294), Expect = 4e-27
Identities = 52/132 (39%), Positives = 80/132 (60%)
Query: 148 NNRTKCDLHVEPEITNIFATSSDAEELKYTWLEWHKAAGAPSKSNFTEYVQMENEAAKLN 207
+N+T ++P++TNI A+S L + W WH AAG P K + ++ + NEA K +
Sbjct: 2 SNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQD 61
Query: 208 GYDTVAEWWLSEYEATDSEDQFAALWAQIKPLYEQIHAYVRGHLRVKYGEEVVPKKGPIP 267
G+ +W S Y + ED L+ Q++PLY +HA+VR L +YG+ + +GPIP
Sbjct: 62 GFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIP 121
Query: 268 AHLLGNIWAQTW 279
AHLLG++WAQ+W
Sbjct: 122 AHLLGDMWAQSW 133
>AY999974-1|ABA39230.1| 47|Homo sapiens angiotensin I converting
enzyme protein.
Length = 47
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/45 (51%), Positives = 30/45 (66%)
Query: 440 INQLYKMGLDKIVFLPFGYLLDLFRYGVFRGTTTVDDYNCHFWQL 484
+N L + L+KI F+PFGYL+DL R+ VF GT D YN +W L
Sbjct: 3 VNFLMHIALEKIAFIPFGYLMDLLRWKVFDGTIWKDIYNQEWWNL 47
>DQ457018-1|ABF00475.1| 42|Homo sapiens angiotensin I converting
enzyme protein.
Length = 42
Score = 47.6 bits (108), Expect = 1e-04
Identities = 22/48 (45%), Positives = 29/48 (60%), Gaps = 6/48 (12%)
Query: 518 RYYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALG 565
RY++S ++QFQFH +LC+ +G L CDIYNS AG LG
Sbjct: 1 RYFLSLVLQFQFHETLCKASGHMGP------LHQCDIYNSKIAGKLLG 42
>DQ458794-1|ABE96829.1| 41|Homo sapiens angiotensin I converting
enzyme protein.
Length = 41
Score = 43.2 bits (97), Expect = 0.003
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 6/47 (12%)
Query: 519 YYISYIIQFQFHRSLCQLAGEYAVGDSSRLLSNCDIYNSTAAGNALG 565
Y++S ++ FQFH +LC+ +G L CDIYNS AG LG
Sbjct: 1 YFLSLVLXFQFHETLCKASGHMGP------LHQCDIYNSKIAGKLLG 41
>AY999973-1|ABA39229.1| 32|Homo sapiens angiotensin I converting
enzyme protein.
Length = 32
Score = 37.9 bits (84), Expect = 0.11
Identities = 13/32 (40%), Positives = 19/32 (59%)
Query: 273 NIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQ 304
N+WAQTW N+ P+P +D T A++ Q
Sbjct: 1 NMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQ 32
>AY999972-1|ABA39228.1| 32|Homo sapiens angiotensin I converting
enzyme protein.
Length = 32
Score = 37.9 bits (84), Expect = 0.11
Identities = 13/32 (40%), Positives = 19/32 (59%)
Query: 273 NIWAQTWGNVEKFTRPYPDKTDIDVTAALIAQ 304
N+WAQTW N+ P+P +D T A++ Q
Sbjct: 1 NMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQ 32
>AK131280-1|BAD18455.1| 974|Homo sapiens protein ( Homo sapiens
cDNA FLJ16228 fis, clone FEBRA2008692, highly similar
to Homo sapiens IRE1b mRNA for protein
kinase/ribonuclease IRE1 beta. ).
Length = 974
Score = 33.5 bits (73), Expect = 2.4
Identities = 16/59 (27%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 553 DIYNSTAAGNALGKMLQLGSSKPWPDAMEAITGQRFMDASGVLEYFQPLYDWLKAENER 611
++++ A + +G ML +P P A + + F + L++FQ + DWL+ E+E+
Sbjct: 795 EVHDKVVARDLVGAMLS-PLPQPRPSAPQVLAHPFFWSRAKQLQFFQDVSDWLEKESEQ 852
>AF068293-1|AAF65182.1| 176|Homo sapiens HDCMB07P protein.
Length = 176
Score = 31.5 bits (68), Expect = 9.6
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 63 ETNLTVHNEQKLLQVSLEVASETKEYWKETMSYLWHEFE-DPDLKRMFKKYTELGTSALP 121
+ N+++ ++ L VS E KE W+E ++ L + + + + KK L S LP
Sbjct: 72 QQNISMQRQENLRWVSELSYVEEKEQWQEQINQLKKQLDFSVSICQTLKK--ALWMSRLP 129
Query: 122 EDLNQRLIVAINSMQSTY 139
L RL+ +N M +Y
Sbjct: 130 SRLTLRLLKKMNMMNRSY 147
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.412
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,313,966
Number of Sequences: 224733
Number of extensions: 4000350
Number of successful extensions: 10125
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 9998
Number of HSP's gapped (non-prelim): 32
length of query: 649
length of database: 73,234,838
effective HSP length: 95
effective length of query: 554
effective length of database: 51,885,203
effective search space: 28744402462
effective search space used: 28744402462
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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