Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002525-TA|BGIBMGA002525-PA|IPR007114|Major facilitator
superfamily, IPR005829|Sugar transporter superfamily, IPR011701|Major
facilitator superfamily MFS_1
(579 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB026898-2|BAA77625.1| 551|Homo sapiens organic-cation transpor... 183 1e-45
AB010438-1|BAA76350.1| 551|Homo sapiens organic-cation transpor... 183 1e-45
AL162582-1|CAI20003.1| 555|Homo sapiens solute carrier family 2... 175 5e-43
X98333-1|CAA66978.1| 555|Homo sapiens organic cation transporte... 173 1e-42
BC039899-1|AAH39899.1| 555|Homo sapiens solute carrier family 2... 173 1e-42
BC012325-1|AAH12325.1| 557|Homo sapiens solute carrier family 2... 171 4e-42
AF057164-1|AAC24828.1| 557|Homo sapiens organic cation transpor... 171 8e-42
AB016625-1|BAA36712.1| 557|Homo sapiens OCTN2 protein. 171 8e-42
AB015050-1|BAA29023.1| 557|Homo sapiens OCTN2 protein. 171 8e-42
AL591069-1|CAI16539.1| 556|Homo sapiens solute carrier family 2... 168 4e-41
AL355506-1|CAI20340.1| 556|Homo sapiens solute carrier family 2... 168 4e-41
AJ001417-1|CAA04751.1| 556|Homo sapiens extraneuronal monoamine... 168 4e-41
AJ403946-1|CAC39443.1| 557|Homo sapiens organic cation transpor... 164 7e-40
BC035973-1|AAH35973.1| 468|Homo sapiens SLC22A13 protein protein. 161 6e-39
U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporte... 157 1e-37
AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 2... 157 1e-37
X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporte... 156 2e-37
BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 2... 156 2e-37
BC033682-1|AAH33682.1| 550|Homo sapiens solute carrier family 2... 153 2e-36
AJ249369-1|CAB77184.1| 563|Homo sapiens organic anion transport... 153 2e-36
AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens ... 153 2e-36
AF124373-1|AAD55356.1| 550|Homo sapiens organic anion transport... 153 2e-36
AF097490-1|AAD19356.1| 550|Homo sapiens organic anion transport... 153 2e-36
AF057039-1|AAC70004.1| 550|Homo sapiens putative renal organic ... 153 2e-36
AB009698-1|BAA75073.1| 550|Homo sapiens hOAT1-2 protein. 153 2e-36
AB009697-1|BAA75072.1| 563|Homo sapiens hOAT1-1 protein. 153 2e-36
AB291606-1|BAF45812.1| 581|Homo sapiens organic cation transpor... 152 4e-36
AF104038-1|AAD10052.1| 550|Homo sapiens para-aminohippurate tra... 151 9e-36
AK222869-1|BAD96589.1| 550|Homo sapiens solute carrier family 2... 148 5e-35
BC034384-1|AAH34384.1| 550|Homo sapiens solute carrier family 2... 146 1e-34
AC044790-3|AAK68155.1| 550|Homo sapiens OAT4 protein. 146 1e-34
AB026116-1|BAA95316.1| 550|Homo sapiens organic anion transport... 146 1e-34
AB042505-1|BAB47393.1| 542|Homo sapiens organic anion transport... 143 1e-33
AB007448-1|BAA23356.1| 551|Homo sapiens OCTN1 protein. 142 2e-33
Y09881-1|CAA71007.1| 551|Homo sapiens ergothioneine transporter... 142 3e-33
BC028313-1|AAH28313.1| 551|Homo sapiens solute carrier family 2... 142 3e-33
AY145501-1|AAN52927.1| 547|Homo sapiens putative transmembrane ... 142 3e-33
AL365318-2|CAH70686.1| 547|Homo sapiens solute carrier family 2... 142 3e-33
AL357137-2|CAH70380.1| 547|Homo sapiens solute carrier family 2... 142 3e-33
BC022387-1|AAH22387.1| 542|Homo sapiens solute carrier family 2... 142 4e-33
AL583834-4|CAI14464.1| 546|Homo sapiens solute carrier family 2... 139 2e-32
BC026358-1|AAH26358.1| 535|Homo sapiens solute carrier family 2... 139 3e-32
AB075951-1|BAC02720.1| 483|Homo sapiens organic cation transpor... 138 4e-32
BC033805-1|AAH33805.1| 548|Homo sapiens solute carrier family 2... 137 1e-31
AY050498-1|AAL12496.1| 548|Homo sapiens organic anion transport... 137 1e-31
AL583834-5|CAI14463.1| 548|Homo sapiens solute carrier family 2... 137 1e-31
AL583834-3|CAI14462.1| 539|Homo sapiens solute carrier family 2... 137 1e-31
AF097518-1|AAD37091.1| 548|Homo sapiens liver-specific transpor... 137 1e-31
AJ271205-1|CAB97249.1| 519|Homo sapiens putative organic anion ... 136 2e-31
AJ251529-1|CAB94830.1| 506|Homo sapiens putative organic anion ... 136 2e-31
AF210455-1|AAG43523.1| 539|Homo sapiens organic anion transport... 135 4e-31
BC101316-1|AAI01317.1| 547|Homo sapiens LOC387601 protein protein. 130 1e-29
AB026898-3|BAA77626.1| 594|Homo sapiens organic-cation transpor... 130 1e-29
AB011082-1|BAA76351.1| 594|Homo sapiens organic-cation transpor... 130 1e-29
AY437532-1|AAR84082.1| 547|Homo sapiens putative UST1-like orga... 129 2e-29
BC130543-1|AAI30544.1| 594|Homo sapiens solute carrier family 2... 128 7e-29
BC075071-1|AAH75071.1| 594|Homo sapiens solute carrier family 2... 128 7e-29
BC075070-1|AAH75070.1| 594|Homo sapiens solute carrier family 2... 128 7e-29
BC126482-1|AAI26483.1| 594|Homo sapiens solute carrier family 2... 124 9e-28
BC126288-1|AAI26289.1| 553|Homo sapiens solute carrier family 2... 123 2e-27
AK074246-1|BAB85030.1| 552|Homo sapiens protein ( Homo sapiens ... 123 2e-27
AJ295270-1|CAC82910.1| 553|Homo sapiens putative integral membr... 123 2e-27
AF440402-1|AAP97316.1| 553|Homo sapiens putative integral membr... 123 2e-27
AB074812-1|BAF51552.1| 553|Homo sapiens organic anion transport... 123 2e-27
AB062418-1|BAB83517.1| 553|Homo sapiens hUST3 protein. 120 1e-26
BC053348-1|AAH53348.1| 553|Homo sapiens solute carrier family 2... 113 2e-24
AC044790-2|AAK68156.1| 553|Homo sapiens RST protein. 113 2e-24
AB071863-1|BAB96750.1| 553|Homo sapiens URAT1 protein. 113 2e-24
AK129930-1|BAC85252.1| 442|Homo sapiens er 11 (SLC22A11). prot... 112 4e-24
AK075224-1|BAC11483.1| 401|Homo sapiens protein ( Homo sapiens ... 112 4e-24
AL162582-2|CAI20004.1| 334|Homo sapiens solute carrier family 2... 110 2e-23
BC034394-1|AAH34394.1| 322|Homo sapiens hypothetical protein MG... 107 1e-22
AB209484-1|BAD92721.1| 440|Homo sapiens solute carrier family 2... 106 2e-22
BC047565-1|AAH47565.1| 577|Homo sapiens solute carrier family 2... 105 4e-22
AL050350-4|CAI42512.1| 577|Homo sapiens solute carrier family 2... 105 4e-22
AB055798-1|BAC23062.1| 543|Homo sapiens carnitine transporter 2... 105 4e-22
AF268892-1|AAK58593.1| 577|Homo sapiens organic cation transpor... 103 2e-21
AY145502-1|AAN52928.1| 577|Homo sapiens putative transmembrane ... 101 7e-21
AF097491-1|AAD19357.1| 568|Homo sapiens organic anion transport... 99 5e-20
BC101315-1|AAI01316.1| 398|Homo sapiens LOC387601 protein protein. 97 1e-19
AB050269-1|BAB68364.1| 552|Homo sapiens organic anion transpote... 97 1e-19
AL050350-6|CAI42514.1| 432|Homo sapiens solute carrier family 2... 95 8e-19
AC002464-1|AAB67044.1| 456|Homo sapiens WUGSC:RG331P03.1 protein. 89 4e-17
AK057306-1|BAB71419.1| 361|Homo sapiens protein ( Homo sapiens ... 85 6e-16
AK131327-1|BAD18487.1| 349|Homo sapiens protein ( Homo sapiens ... 73 2e-12
BC026291-1|AAH26291.1| 440|Homo sapiens Unknown (protein for IM... 69 3e-11
BC030978-1|AAH30978.1| 242|Homo sapiens SLC22A2 protein protein. 69 5e-11
BC101314-1|AAI01315.1| 201|Homo sapiens LOC387601 protein protein. 64 2e-09
BC022379-1|AAH22379.1| 238|Homo sapiens SLC22A9 protein protein. 62 7e-09
BC040876-1|AAH40876.1| 341|Homo sapiens C6orf85 protein protein. 60 2e-08
AL445309-6|CAI40959.1| 213|Homo sapiens chromosome 6 open readi... 60 2e-08
AL160398-1|CAI12303.1| 213|Homo sapiens chromosome 6 open readi... 60 2e-08
AB075876-1|BAD38658.1| 269|Homo sapiens putative protein produc... 57 1e-07
AY358258-1|AAQ88625.1| 245|Homo sapiens trans-like protein prot... 56 3e-07
AL365318-1|CAH70685.1| 245|Homo sapiens solute carrier family 2... 56 3e-07
AL357137-1|CAH70379.1| 245|Homo sapiens solute carrier family 2... 56 3e-07
AK128610-1|BAC87527.1| 221|Homo sapiens . protein. 55 6e-07
BC020565-1|AAH20565.1| 538|Homo sapiens solute carrier family 2... 54 1e-06
AK127610-1|BAC87056.1| 248|Homo sapiens protein ( Homo sapiens ... 53 2e-06
BC090870-1|AAH90870.1| 449|Homo sapiens SLC22A17 protein protein. 53 3e-06
BC094722-1|AAH94722.1| 548|Homo sapiens SV2 related protein hom... 50 2e-05
BC033587-1|AAH33587.1| 548|Homo sapiens SV2 related protein hom... 50 2e-05
AL583834-7|CAI14466.1| 211|Homo sapiens solute carrier family 2... 50 2e-05
CR457086-1|CAG33367.1| 683|Homo sapiens SV2B protein. 49 4e-05
BC030011-1|AAH30011.1| 683|Homo sapiens SV2B protein protein. 49 4e-05
AY358183-1|AAQ88550.1| 445|Homo sapiens SLC22A12 protein. 49 4e-05
AB018278-1|BAA34455.2| 707|Homo sapiens KIAA0735 protein protein. 49 4e-05
Y17801-1|CAB89809.1| 477|Homo sapiens glucose transporter 8 pro... 48 1e-04
BC019043-1|AAH19043.1| 477|Homo sapiens solute carrier family 2... 48 1e-04
AL583834-6|CAI14465.1| 147|Homo sapiens solute carrier family 2... 48 1e-04
AL445222-5|CAH72918.1| 477|Homo sapiens solute carrier family 2... 48 1e-04
AL445222-4|CAH72917.1| 411|Homo sapiens solute carrier family 2... 48 1e-04
AJ245937-1|CAB75702.1| 477|Homo sapiens glucose transporter pro... 48 1e-04
AK075127-1|BAC11419.1| 248|Homo sapiens protein ( Homo sapiens ... 46 5e-04
BC101317-1|AAI01318.1| 168|Homo sapiens LOC387601 protein protein. 45 6e-04
BC060766-1|AAH60766.1| 497|Homo sapiens SLC2A14 protein protein. 45 6e-04
AY357941-1|AAQ63763.1| 497|Homo sapiens glucose transporter 14 ... 45 6e-04
AF481879-1|AAL89710.1| 520|Homo sapiens glucose transporter 14 ... 45 6e-04
AF481878-1|AAL89709.1| 497|Homo sapiens glucose transporter 14 ... 45 6e-04
AL583834-2|CAI14461.1| 278|Homo sapiens solute carrier family 2... 44 0.002
BX537754-1|CAD97824.1| 742|Homo sapiens hypothetical protein pr... 43 0.003
BC045111-1|AAH45111.1| 742|Homo sapiens synaptic vesicle glycop... 43 0.003
BC000776-1|AAH00776.2| 604|Homo sapiens SV2A protein protein. 43 0.003
AL591493-21|CAI12573.1| 682|Homo sapiens synaptic vesicle glyco... 43 0.003
AL591493-20|CAI12572.1| 742|Homo sapiens synaptic vesicle glyco... 43 0.003
AK075480-1|BAC11645.1| 682|Homo sapiens protein ( Homo sapiens ... 43 0.003
AB018279-1|BAA34456.2| 748|Homo sapiens KIAA0736 protein protein. 43 0.003
DQ658848-1|ABG45942.1| 207|Homo sapiens esophageal carcinoma NG... 41 0.010
BC100827-1|AAI00828.1| 727|Homo sapiens synaptic vesicle glycop... 41 0.010
BC100826-1|AAI00827.1| 727|Homo sapiens synaptic vesicle glycop... 41 0.010
BC100825-1|AAI00826.1| 727|Homo sapiens synaptic vesicle glycop... 41 0.010
K03195-1|AAA52571.1| 492|Homo sapiens SGLT1 protein. 40 0.032
BC128580-1|AAI28581.1| 405|Homo sapiens C6orf85 protein protein. 40 0.032
BC100824-1|AAI00825.1| 727|Homo sapiens synaptic vesicle glycop... 40 0.032
M20681-1|AAB61083.1| 496|Homo sapiens protein ( Human glucose t... 39 0.056
CR457413-1|CAG33694.1| 496|Homo sapiens ber 3; complete cds, in... 39 0.056
BC039196-1|AAH39196.1| 496|Homo sapiens SLC2A3 protein protein. 39 0.056
AY517500-1|AAS76641.1| 234|Homo sapiens putative integral membr... 39 0.056
AK091990-1|BAC03786.1| 234|Homo sapiens protein ( Homo sapiens ... 39 0.056
AF274892-1|AAF82116.1| 496|Homo sapiens glucose transporter 3 p... 39 0.056
BC121804-1|AAI21805.1| 492|Homo sapiens solute carrier family 2... 38 0.097
BC118590-1|AAI18591.1| 492|Homo sapiens solute carrier family 2... 38 0.097
BC111015-1|AAI11016.1| 403|Homo sapiens SLC22A17 protein protein. 38 0.097
AJ243653-1|CAC01119.1| 366|Homo sapiens organic cation transpor... 38 0.097
AJ243122-1|CAC17762.1| 366|Homo sapiens organic cation transpor... 38 0.097
AB208987-1|BAD92224.1| 517|Homo sapiens solute carrier family 2... 38 0.097
BC117119-1|AAI17120.1| 629|Homo sapiens solute carrier family 2... 38 0.13
BC117117-1|AAI17118.1| 629|Homo sapiens solute carrier family 2... 38 0.13
BC047507-1|AAH47507.1| 338|Homo sapiens SLC2A13 protein protein. 38 0.13
U11843-1|AAB60641.1| 481|Homo sapiens fructose transporter prot... 37 0.17
AJ315644-1|CAC51116.1| 629|Homo sapiens proton myo-inositol tra... 37 0.17
M91463-1|AAA52569.1| 505|Homo sapiens glucose transporter protein. 37 0.22
M55531-1|AAA52570.1| 501|Homo sapiens GLUT5 protein protein. 37 0.22
BC001820-1|AAH01820.1| 501|Homo sapiens solute carrier family 2... 37 0.22
BC001692-1|AAH01692.1| 501|Homo sapiens solute carrier family 2... 37 0.22
AL158048-3|CAI23458.1| 501|Homo sapiens solute carrier family 2... 37 0.22
M20747-1|AAA59189.1| 509|Homo sapiens GLUT4 protein. 36 0.52
BC126164-1|AAI26165.1| 509|Homo sapiens solute carrier family 2... 36 0.52
BC113592-1|AAI13593.1| 509|Homo sapiens solute carrier family 2... 36 0.52
BC069621-1|AAH69621.1| 509|Homo sapiens solute carrier family 2... 36 0.52
BC069615-1|AAH69615.1| 509|Homo sapiens solute carrier family 2... 36 0.52
BC034387-1|AAH34387.1| 415|Homo sapiens SLC2A4 protein protein. 36 0.52
J03810-1|AAA59514.1| 524|Homo sapiens GLUT2 protein. 35 0.91
BC036796-1|AAH36796.1| 340|Homo sapiens SVOP-like protein. 35 0.91
AJ251884-1|CAB96132.1| 143|Homo sapiens extraneuronal monoamine... 33 2.1
Y17803-1|CAB96996.1| 507|Homo sapiens facilitataive glucose tra... 33 2.8
BC013740-1|AAH13740.1| 507|Homo sapiens solute carrier family 2... 33 2.8
AL593848-7|CAI17254.1| 445|Homo sapiens solute carrier family 2... 33 2.8
AL593848-6|CAI17253.1| 507|Homo sapiens solute carrier family 2... 33 2.8
AK222919-1|BAD96639.1| 507|Homo sapiens solute carrier family 2... 33 2.8
AK074927-1|BAC11297.1| 507|Homo sapiens protein ( Homo sapiens ... 33 2.8
AK074836-1|BAC11235.1| 445|Homo sapiens r-4. protein. 33 2.8
AJ011372-1|CAB66155.1| 507|Homo sapiens sugar transporter protein. 33 2.8
BC030693-1|AAH30693.1| 478|Homo sapiens solute carrier family 1... 33 3.7
AF058056-1|AAC13721.1| 478|Homo sapiens monocarboxylate transpo... 33 3.7
AF049608-1|AAC70919.1| 478|Homo sapiens monocarboxylate transpo... 33 3.7
BC035878-1|AAH35878.1| 244|Homo sapiens SLC2A5 protein protein. 31 8.4
AL158048-2|CAI23457.1| 244|Homo sapiens solute carrier family 2... 31 8.4
AF479408-1|AAL87107.1| 107|Homo sapiens glucose transporter-lik... 31 8.4
>AB026898-2|BAA77625.1| 551|Homo sapiens organic-cation transporter
like 3 protein.
Length = 551
Score = 183 bits (446), Expect = 1e-45
Identities = 125/523 (23%), Positives = 232/523 (44%), Gaps = 18/523 (3%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWC--WVPELA-NLT 89
F ++L G+FG +QI L F +++ +F+ P+H WV NL+
Sbjct: 4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLS 63
Query: 90 DTERRTLAIPIDDSTKFGYSH-CQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L++P+D + G+ C ++ + + + T+ C+ GWE+ + +
Sbjct: 64 AAEQLVLSVPLDTA---GHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRL 120
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
P ++ +E + +CDR + T Q++F G ++G + G + DR GR + L+ L
Sbjct: 121 P--SLKNEFNLVCDRKHLKDTTQSVFMGGLLVGTLMFGPLCDRIGRKATILAQLLLFTLI 178
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G+ T F +F + RF A +L E+V P ++T +A F
Sbjct: 179 GLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLG-Q 237
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + ++ +W+ + I + +PES RWLL+ GR++EAI I + +
Sbjct: 238 MVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASV 297
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR-TFILMCLEFTCCTIIFDALV 387
N + + E S + L++F+ P +R+ T I+ C+ F ++ + L
Sbjct: 298 NRRKLSPELMNQ----LVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFV-DSLGYYGLS 352
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
G G E+P+ C F+M GRKW +G ++L + ++ +F+ +
Sbjct: 353 LQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPA 412
Query: 448 GVPSV--MCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVY 505
+P V M V+ + ++ + ++AE+ PT +R +G +V I IG L+P ++
Sbjct: 413 DLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVIL 472
Query: 506 LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
L Y + LP LPET + + T + E
Sbjct: 473 LGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQDLE 515
>AB010438-1|BAA76350.1| 551|Homo sapiens organic-cation transporter
like 3 protein.
Length = 551
Score = 183 bits (446), Expect = 1e-45
Identities = 125/523 (23%), Positives = 232/523 (44%), Gaps = 18/523 (3%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWC--WVPELA-NLT 89
F ++L G+FG +QI L F +++ +F+ P+H WV NL+
Sbjct: 4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLS 63
Query: 90 DTERRTLAIPIDDSTKFGYSH-CQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L++P+D + G+ C ++ + + + T+ C+ GWE+ + +
Sbjct: 64 AAEQLVLSVPLDTA---GHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRL 120
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
P ++ +E + +CDR + T Q++F G ++G + G + DR GR + L+ L
Sbjct: 121 P--SLKNEFNLVCDRKHLKDTTQSVFMGGLLVGTLMFGPLCDRIGRKATILAQLLLFTLI 178
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G+ T F +F + RF A +L E+V P ++T +A F
Sbjct: 179 GLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLG-Q 237
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + ++ +W+ + I + +PES RWLL+ GR++EAI I + +
Sbjct: 238 MVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASV 297
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR-TFILMCLEFTCCTIIFDALV 387
N + + E S + L++F+ P +R+ T I+ C+ F ++ + L
Sbjct: 298 NRRKLSPELMNQ----LVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFV-DSLGYYGLS 352
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
G G E+P+ C F+M GRKW +G ++L + ++ +F+ +
Sbjct: 353 LQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPA 412
Query: 448 GVPSV--MCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVY 505
+P V M V+ + ++ + ++AE+ PT +R +G +V I IG L+P ++
Sbjct: 413 DLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVIL 472
Query: 506 LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
L Y + LP LPET + + T + E
Sbjct: 473 LGEYHAALPMLIYGSLPIVAGLLCTLLPETHGQGLKDTLQDLE 515
>AL162582-1|CAI20003.1| 555|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 555
Score = 175 bits (425), Expect = 5e-43
Identities = 138/542 (25%), Positives = 237/542 (43%), Gaps = 36/542 (6%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLT---- 89
D++L GEF +Q +FF + +Y +F+ +P+H C P +A L+
Sbjct: 6 DDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGF-TPDHRCRSPGVAELSLRCG 64
Query: 90 --DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV-------LIAGQIPNSTWPTKACEH 139
E +P + + C+ Y+ +W++ L + S P C
Sbjct: 65 WSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRD 124
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + E P +I +E + +C Q+ VG IG IG++ADR+GR +
Sbjct: 125 GWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLL 181
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ LI G+L + +T I+R I G+ ++ Y+++ E+V +Y+ V +
Sbjct: 182 TTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTV-GIF 240
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + YT + + ++ A HW+ + S CIPESPRWL+S + EA+
Sbjct: 241 YQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKNAEAM 300
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKET-KEESHSCLEIFKRPPIRR-TFILMCLEFT 377
I I++ N + + +ET K+ + S L++ + P IR+ T ILM FT
Sbjct: 301 RIIKHIAKKNGKSLPASLQ---RLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT 357
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
++++ L+ G G E P+ ++ +D +GR++ M+
Sbjct: 358 -SSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGA 416
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY- 494
L +VF+ + ++ + L R + ++Y AE+ PT +R G VHIC
Sbjct: 417 ACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLG---VHICSSM 473
Query: 495 --IGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
IG ++P++VY I W LP LPET K +P+T EAE +
Sbjct: 474 CDIGGIITPFLVYRLTNI-WLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENM 532
Query: 551 SR 552
R
Sbjct: 533 QR 534
>X98333-1|CAA66978.1| 555|Homo sapiens organic cation transporter
protein.
Length = 555
Score = 173 bits (422), Expect = 1e-42
Identities = 137/542 (25%), Positives = 237/542 (43%), Gaps = 36/542 (6%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLT---- 89
D++L GEF +Q +FF + +Y +F+ +P+H C P +A L+
Sbjct: 6 DDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGF-TPDHRCRSPGVAELSLRCG 64
Query: 90 --DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV-------LIAGQIPNSTWPTKACEH 139
E +P + + C+ Y+ +W++ L + S P C
Sbjct: 65 WSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRD 124
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + E P +I +E + +C Q+ VG IG IG++ADR+GR +
Sbjct: 125 GWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLL 181
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ LI G+L + +T I+R I G+ ++ Y+++ E+V +Y+ V +
Sbjct: 182 TTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTV-GIF 240
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + YT + + ++ A HW+ + + CIPESPRWL+S + EA+
Sbjct: 241 YQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAM 300
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKET-KEESHSCLEIFKRPPIRR-TFILMCLEFT 377
I I++ N + + +ET K+ + S L++ + P IR+ T ILM FT
Sbjct: 301 RIIKHIAKKNGKSLPASLQ---RLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT 357
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
++++ L+ G G E P+ ++ +D +GR++ M+
Sbjct: 358 -SSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGA 416
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY- 494
L +VF+ + ++ + L R + ++Y AE+ PT +R G VHIC
Sbjct: 417 ACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLG---VHICSSM 473
Query: 495 --IGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
IG ++P++VY I W LP LPET K +P+T EAE +
Sbjct: 474 CDIGGIITPFLVYRLTNI-WLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENM 532
Query: 551 SR 552
R
Sbjct: 533 QR 534
>BC039899-1|AAH39899.1| 555|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 555
Score = 173 bits (422), Expect = 1e-42
Identities = 137/542 (25%), Positives = 237/542 (43%), Gaps = 36/542 (6%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLT---- 89
D++L GEF +Q +FF + +Y +F+ +P+H C P +A L+
Sbjct: 6 DDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGF-TPDHRCRSPGVAELSLRCG 64
Query: 90 --DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV-------LIAGQIPNSTWPTKACEH 139
E +P + + C+ Y+ +W++ L + S P C
Sbjct: 65 WSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRD 124
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + E P +I +E + +C Q+ VG IG IG++ADR+GR +
Sbjct: 125 GWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLL 181
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ LI G+L + +T I+R I G+ ++ Y+++ E+V +Y+ V +
Sbjct: 182 TTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTV-GIF 240
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + YT + + ++ A HW+ + + CIPESPRWL+S + EA+
Sbjct: 241 YQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAM 300
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKET-KEESHSCLEIFKRPPIRR-TFILMCLEFT 377
I I++ N + + +ET K+ + S L++ + P IR+ T ILM FT
Sbjct: 301 RIIKHIAKKNGKSLPASLQ---RLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT 357
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
++++ L+ G G E P+ ++ +D +GR++ M+
Sbjct: 358 -SSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGA 416
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY- 494
L +VF+ + ++ + L R + ++Y AE+ PT +R G VHIC
Sbjct: 417 ACLASVFIPGDLQWLKIIISCLGRMGITMAYEIVCLVNAELYPTFIRNLG---VHICSSM 473
Query: 495 --IGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
IG ++P++VY I W LP LPET K +P+T EAE +
Sbjct: 474 CDIGGIITPFLVYRLTNI-WLELPLMVFGVLGLVAGGLVLLLPETKGKALPETIEEAENM 532
Query: 551 SR 552
R
Sbjct: 533 QR 534
>BC012325-1|AAH12325.1| 557|Homo sapiens solute carrier family 22
(organic cation transporter), member 5 protein.
Length = 557
Score = 171 bits (417), Expect = 4e-42
Identities = 124/524 (23%), Positives = 231/524 (44%), Gaps = 12/524 (2%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE+ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIA-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R T+ + + D + +S C+ Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNHTVPLRLRDGREVPHS-CRRYRLATIANFSALGLEPGRDVDLGQLEQESCPDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ TI +E + +C+ +LFFVG ++G F+ G ++DR+GR + +
Sbjct: 121 Q-DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM 179
Query: 205 GCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFY 264
L F++NF F + + GM + + A+++ E + + + + + +FY
Sbjct: 180 QTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFY 239
Query: 265 TSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILT 324
+ +P + W+ + + + IPESPRWL+S GR EEA I
Sbjct: 240 AFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRK 299
Query: 325 ISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFD 384
++ N + K++SH+ L++ + IR I+ + + ++ +
Sbjct: 300 AAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYF 359
Query: 385 ALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVF 444
L T L E+P+ + ++ ++ R++ + L L
Sbjct: 360 GLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQL 419
Query: 445 VGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
V + + + ++ +F V +++ +TAE+ PT VR G V +G+ LSPY
Sbjct: 420 VPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPY 479
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
VYL Y +LP LPE+ +P T ++
Sbjct: 480 FVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQ 523
>AF057164-1|AAC24828.1| 557|Homo sapiens organic cation transporter
OCTN2 protein.
Length = 557
Score = 171 bits (415), Expect = 8e-42
Identities = 124/524 (23%), Positives = 231/524 (44%), Gaps = 12/524 (2%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE+ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIA-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R T+ + + D + +S C+ Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNHTVPLRLRDGREVPHS-CRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ TI +E + +C+ +LFFVG ++G F+ G ++DR+GR + +
Sbjct: 121 Q-DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM 179
Query: 205 GCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFY 264
L F++NF F + + GM + + A+++ E + + + + + +FY
Sbjct: 180 QTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFY 239
Query: 265 TSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILT 324
+ +P + W+ + + + IPESPRWL+S GR EEA I
Sbjct: 240 AFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRK 299
Query: 325 ISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFD 384
++ N + K++SH+ L++ + IR I+ + + ++ +
Sbjct: 300 AAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYF 359
Query: 385 ALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVF 444
L T L E+P+ + ++ ++ R++ + L L
Sbjct: 360 GLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQL 419
Query: 445 VGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
V + + + ++ +F V +++ +TAE+ PT VR G V +G+ LSPY
Sbjct: 420 VPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPY 479
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
VYL Y +LP LPE+ +P T ++
Sbjct: 480 FVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQ 523
>AB016625-1|BAA36712.1| 557|Homo sapiens OCTN2 protein.
Length = 557
Score = 171 bits (415), Expect = 8e-42
Identities = 124/524 (23%), Positives = 231/524 (44%), Gaps = 12/524 (2%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE+ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIA-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R T+ + + D + +S C+ Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNHTVPLRLRDGREVPHS-CRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ TI +E + +C+ +LFFVG ++G F+ G ++DR+GR + +
Sbjct: 121 Q-DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM 179
Query: 205 GCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFY 264
L F++NF F + + GM + + A+++ E + + + + + +FY
Sbjct: 180 QTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFY 239
Query: 265 TSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILT 324
+ +P + W+ + + + IPESPRWL+S GR EEA I
Sbjct: 240 AFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRK 299
Query: 325 ISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFD 384
++ N + K++SH+ L++ + IR I+ + + ++ +
Sbjct: 300 AAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYF 359
Query: 385 ALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVF 444
L T L E+P+ + ++ ++ R++ + L L
Sbjct: 360 GLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQL 419
Query: 445 VGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
V + + + ++ +F V +++ +TAE+ PT VR G V +G+ LSPY
Sbjct: 420 VPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPY 479
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
VYL Y +LP LPE+ +P T ++
Sbjct: 480 FVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQ 523
>AB015050-1|BAA29023.1| 557|Homo sapiens OCTN2 protein.
Length = 557
Score = 171 bits (415), Expect = 8e-42
Identities = 124/524 (23%), Positives = 231/524 (44%), Gaps = 12/524 (2%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE+ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIA-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R T+ + + D + +S C+ Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNHTVPLRLRDGREVPHS-CRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ TI +E + +C+ +LFFVG ++G F+ G ++DR+GR + +
Sbjct: 121 Q-DVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGM 179
Query: 205 GCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFY 264
L F++NF F + + GM + + A+++ E + + + + + +FY
Sbjct: 180 QTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFY 239
Query: 265 TSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILT 324
+ +P + W+ + + + IPESPRWL+S GR EEA I
Sbjct: 240 AFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRK 299
Query: 325 ISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFD 384
++ N + K++SH+ L++ + IR I+ + + ++ +
Sbjct: 300 AAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYF 359
Query: 385 ALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVF 444
L T L E+P+ + ++ ++ R++ + L L
Sbjct: 360 GLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQL 419
Query: 445 VGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
V + + + ++ +F V +++ +TAE+ PT VR G V +G+ LSPY
Sbjct: 420 VPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPY 479
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
VYL Y +LP LPE+ +P T ++
Sbjct: 480 FVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQ 523
>AL591069-1|CAI16539.1| 556|Homo sapiens solute carrier family 22
(extraneuronal monoamined) (PLP2) pseudogene protein.
Length = 556
Score = 168 bits (409), Expect = 4e-41
Identities = 138/548 (25%), Positives = 240/548 (43%), Gaps = 44/548 (8%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
+FDE L GEFG +Q +F + F++ +F+ ++WC P A L +
Sbjct: 3 SFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAER 62
Query: 92 --------ERRTLAIPIDDSTKFGYSHCQVY--DANWDEVLIAGQI---------PNSTW 132
RT CQ Y +A D + PN +
Sbjct: 63 CGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSA 122
Query: 133 PTKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRY 192
P C GW + + + TI SE D +C QA+ +G + G F +G+ ADRY
Sbjct: 123 PLVPCRGGWRYAQA---HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRY 179
Query: 193 GRLPAAVYSTLIGCLG----GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVT 248
GR+ +Y L+ CLG G++ FA NF F I+RF+ G+ M Y+I+ E V
Sbjct: 180 GRI--VIY--LLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVG 235
Query: 249 PKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRW 308
K + +V + +F+T I +P I+ +W+ I + + +PESPRW
Sbjct: 236 SKQRRIV-GIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRW 294
Query: 309 LLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR- 367
L++ + ++A+ + I++ N + TV+ E + + S L++ + P +R+
Sbjct: 295 LITRKKGDKALQILRRIAKCNGKYLSSNYS---EITVTDE-EVSNPSFLDLVRTPQMRKC 350
Query: 368 TFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWV 427
T ILM FT +++ LV G +G ELP ++ ++ +GR+
Sbjct: 351 TLILMFAWFT-SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLP 409
Query: 428 TIGCMMLCSVFTLLTVFVGSGVPSVMCTV--LARFFVNISYNATMQWTAEVLPTQVRGSG 485
++ V L+T F+ G+ + TV L R + +++ +E+ PT +R G
Sbjct: 410 FAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFG 469
Query: 486 ASVVH-ICGYIGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQ 542
S+ +C + G ++P++++ ++ W LP LPET +P+
Sbjct: 470 VSLCSGLCDF-GGIIAPFLLF-RLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPE 527
Query: 543 TFNEAEEL 550
T ++ E+L
Sbjct: 528 TVDDVEKL 535
>AL355506-1|CAI20340.1| 556|Homo sapiens solute carrier family 22
(extraneuronal monoaminen 1 protein.
Length = 556
Score = 168 bits (409), Expect = 4e-41
Identities = 138/548 (25%), Positives = 240/548 (43%), Gaps = 44/548 (8%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
+FDE L GEFG +Q +F + F++ +F+ ++WC P A L +
Sbjct: 3 SFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAER 62
Query: 92 --------ERRTLAIPIDDSTKFGYSHCQVY--DANWDEVLIAGQI---------PNSTW 132
RT CQ Y +A D + PN +
Sbjct: 63 CGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSA 122
Query: 133 PTKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRY 192
P C GW + + + TI SE D +C QA+ +G + G F +G+ ADRY
Sbjct: 123 PLVPCRGGWRYAQA---HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRY 179
Query: 193 GRLPAAVYSTLIGCLG----GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVT 248
GR+ +Y L+ CLG G++ FA NF F I+RF+ G+ M Y+I+ E V
Sbjct: 180 GRI--VIY--LLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVG 235
Query: 249 PKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRW 308
K + +V + +F+T I +P I+ +W+ I + + +PESPRW
Sbjct: 236 SKQRRIV-GIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRW 294
Query: 309 LLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR- 367
L++ + ++A+ + I++ N + TV+ E + + S L++ + P +R+
Sbjct: 295 LITRKKGDKALQILRRIAKCNGKYLSSNYS---EITVTDE-EVSNPSFLDLVRTPQMRKC 350
Query: 368 TFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWV 427
T ILM FT +++ LV G +G ELP ++ ++ +GR+
Sbjct: 351 TLILMFAWFT-SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLP 409
Query: 428 TIGCMMLCSVFTLLTVFVGSGVPSVMCTV--LARFFVNISYNATMQWTAEVLPTQVRGSG 485
++ V L+T F+ G+ + TV L R + +++ +E+ PT +R G
Sbjct: 410 FAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFG 469
Query: 486 ASVVH-ICGYIGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQ 542
S+ +C + G ++P++++ ++ W LP LPET +P+
Sbjct: 470 VSLCSGLCDF-GGIIAPFLLF-RLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPE 527
Query: 543 TFNEAEEL 550
T ++ E+L
Sbjct: 528 TVDDVEKL 535
>AJ001417-1|CAA04751.1| 556|Homo sapiens extraneuronal monoamine
transporter protein.
Length = 556
Score = 168 bits (409), Expect = 4e-41
Identities = 138/548 (25%), Positives = 240/548 (43%), Gaps = 44/548 (8%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
+FDE L GEFG +Q +F + F++ +F+ ++WC P A L +
Sbjct: 3 SFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAER 62
Query: 92 --------ERRTLAIPIDDSTKFGYSHCQVY--DANWDEVLIAGQI---------PNSTW 132
RT CQ Y +A D + PN +
Sbjct: 63 CGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSA 122
Query: 133 PTKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRY 192
P C GW + + + TI SE D +C QA+ +G + G F +G+ ADRY
Sbjct: 123 PLVPCRGGWRYAQA---HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRY 179
Query: 193 GRLPAAVYSTLIGCLG----GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVT 248
GR+ +Y L+ CLG G++ FA NF F I+RF+ G+ M Y+I+ E V
Sbjct: 180 GRI--VIY--LLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVG 235
Query: 249 PKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRW 308
K + +V + +F+T I +P I+ +W+ I + + +PESPRW
Sbjct: 236 SKQRRIV-GIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRW 294
Query: 309 LLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR- 367
L++ + ++A+ + I++ N + TV+ E + + S L++ + P +R+
Sbjct: 295 LITRKKGDKALQILRRIAKCNGKYLSSNYS---EITVTDE-EVSNPSFLDLVRTPQMRKC 350
Query: 368 TFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWV 427
T ILM FT +++ LV G +G ELP ++ ++ +GR+
Sbjct: 351 TLILMFAWFT-SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLP 409
Query: 428 TIGCMMLCSVFTLLTVFVGSGVPSVMCTV--LARFFVNISYNATMQWTAEVLPTQVRGSG 485
++ V L+T F+ G+ + TV L R + +++ +E+ PT +R G
Sbjct: 410 FAASNIVAGVACLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFG 469
Query: 486 ASVVH-ICGYIGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIPQ 542
S+ +C + G ++P++++ ++ W LP LPET +P+
Sbjct: 470 VSLCSGLCDF-GGIIAPFLLF-RLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPE 527
Query: 543 TFNEAEEL 550
T ++ E+L
Sbjct: 528 TVDDVEKL 535
>AJ403946-1|CAC39443.1| 557|Homo sapiens organic cation transporter
3 protein.
Length = 557
Score = 164 bits (399), Expect = 7e-40
Identities = 138/549 (25%), Positives = 241/549 (43%), Gaps = 45/549 (8%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
+FDE L GEFG +Q +F + F++ +F+ ++WC P A L +
Sbjct: 3 SFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAER 62
Query: 92 --------ERRTLAIPIDDSTKFGYSHCQVY--DANWDEVLIAGQI---------PNSTW 132
RT CQ Y +A D + PN +
Sbjct: 63 CGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNRSA 122
Query: 133 PTKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRY 192
P C GW + + + TI SE D +C QA+ +G + G F +G+ ADRY
Sbjct: 123 PLVPCRGGWRYAQA---HSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRY 179
Query: 193 GRLPAAVYSTLIGCLG----GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVT 248
GR+ +Y L+ CLG G++ FA NF F I+RF+ G+ M Y+I+ E V
Sbjct: 180 GRI--VIY--LLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVG 235
Query: 249 PKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRW 308
K + +V + +F+T I +P I+ +W+ I + + +PESPRW
Sbjct: 236 SKQRRIV-GIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRW 294
Query: 309 LLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR- 367
L++ + ++A+ + I++ N + TV+ E + + S L++ + P +R+
Sbjct: 295 LITRKKGDKALQILRRIAKCNGKYLSSNYS---EITVTDE-EVSNPSFLDLVRTPQMRKC 350
Query: 368 TFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWV 427
T ILM FT +++ LV G +G ELP ++ ++ +GR+
Sbjct: 351 TLILMFAWFT-SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLP 409
Query: 428 TIGCMMLCSVFTLLTVFV-GSGVPSVMCTV--LARFFVNISYNATMQWTAEVLPTQVRGS 484
++ V L+T F+ +G+ + TV L R + +++ +E+ PT +R
Sbjct: 410 FAASNIVAGVACLVTAFLPEAGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNF 469
Query: 485 GASVVH-ICGYIGTALSPYIVYLQIYISW--LPXXXXXXXXXXXXXXXXXLPETTKKDIP 541
G S+ +C + G ++P++++ ++ W LP LPET +P
Sbjct: 470 GVSLCSGLCDF-GGIIAPFLLF-RLAAVWLELPLIIFGILASICGGLVMLLPETKGIALP 527
Query: 542 QTFNEAEEL 550
+T ++ E+L
Sbjct: 528 ETVDDVEKL 536
>BC035973-1|AAH35973.1| 468|Homo sapiens SLC22A13 protein protein.
Length = 468
Score = 161 bits (391), Expect = 6e-39
Identities = 108/457 (23%), Positives = 205/457 (44%), Gaps = 18/457 (3%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWC--WVPELA-NLT 89
F ++L G+FG +QI L F +++ +F+ P+H WV NL+
Sbjct: 4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMILDEPHHCAVAWVKNHTFNLS 63
Query: 90 DTERRTLAIPIDDSTKFGYSH-CQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L++P+D + G+ C ++ + + + T+ C+ GWE+ + +
Sbjct: 64 AAEQLVLSVPLDTA---GHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRL 120
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
P ++ +E + +CDR + T Q++F G ++G + G + DR GR + L+ L
Sbjct: 121 P--SLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLI 178
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G+ T F +F + RF A +L E+V P ++T +A F
Sbjct: 179 GLATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLG-Q 237
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + ++ +W+ + I + +PES RWLL+ GR++EAI I + +
Sbjct: 238 MVLAGLAYGFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASV 297
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRR-TFILMCLEFTCCTIIFDALV 387
N + + E S + L++F+ P +R+ T I+ C+ F ++ + L
Sbjct: 298 NRRKLSPELMNQ----LVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFV-DSLGYYGLS 352
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
G G E+P+ C F+M GRKW +G ++L + ++ +F+ +
Sbjct: 353 LQVGDFGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPA 412
Query: 448 GVPSV--MCTVLARFFVNISYNATMQWTAEVLPTQVR 482
+P V M V+ + ++ + ++AE PT +R
Sbjct: 413 DLPVVVTMLAVVGKMATAAAFTISYVYSAEFFPTILR 449
>U77086-1|AAB67703.1| 554|Homo sapiens organic cation transporter 1
protein.
Length = 554
Score = 157 bits (381), Expect = 1e-37
Identities = 127/537 (23%), Positives = 226/537 (42%), Gaps = 26/537 (4%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD--- 90
D++L GE G +Q F + +F+ +P+H C P +A L+
Sbjct: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGF-TPDHHCQSPGVAELSQRCG 63
Query: 91 ---TERRTLAIP-IDDSTKFGYSHCQVYDANWDEVLIAGQIP-------NSTWPTKACEH 139
E +P + + + C+ Y+ +W++ ++ P S P C+
Sbjct: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + + P +I +E + +C Q+ G + G +G+ ADR+GR +
Sbjct: 124 GWVY---DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ L+ + G+L F+ N+ ++R + G+ M Y ++ E+V + VA M
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM- 239
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + +T +A+ ++ A HW+ + + S C+PESPRWLLS R EAI
Sbjct: 240 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIR-RTFILMCLEFTC 378
+ I++ N + T++ S S ++F+ P +R RTFILM L FT
Sbjct: 300 KIMDHIAQKN--GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT- 356
Query: 379 CTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVF 438
++++ L+ G E+P + +D +GR + +L
Sbjct: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Query: 439 TLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIG 496
L+ +F+ + +++ + R + I+ AE+ PT VR G V IG
Sbjct: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG 476
Query: 497 TALSPYIVY-LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSR 552
++P+IV+ L+ LP LPET +P+T +AE L R
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGR 533
>AL353625-3|CAH72016.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 157 bits (381), Expect = 1e-37
Identities = 127/537 (23%), Positives = 226/537 (42%), Gaps = 26/537 (4%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD--- 90
D++L GE G +Q F + +F+ +P+H C P +A L+
Sbjct: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGF-TPDHHCQSPGVAELSQRCG 63
Query: 91 ---TERRTLAIP-IDDSTKFGYSHCQVYDANWDEVLIAGQIP-------NSTWPTKACEH 139
E +P + + + C+ Y+ +W++ ++ P S P C+
Sbjct: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + + P +I +E + +C Q+ G + G +G+ ADR+GR +
Sbjct: 124 GWVY---DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ L+ + G+L F+ N+ ++R + G+ M Y ++ E+V + VA M
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM- 239
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + +T +A+ ++ A HW+ + + S C+PESPRWLLS R EAI
Sbjct: 240 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIR-RTFILMCLEFTC 378
+ I++ N + T++ S S ++F+ P +R RTFILM L FT
Sbjct: 300 KIMDHIAQKN--GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT- 356
Query: 379 CTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVF 438
++++ L+ G E+P + +D +GR + +L
Sbjct: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Query: 439 TLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIG 496
L+ +F+ + +++ + R + I+ AE+ PT VR G V IG
Sbjct: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG 476
Query: 497 TALSPYIVY-LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSR 552
++P+IV+ L+ LP LPET +P+T +AE L R
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGR 533
>X98332-1|CAA66977.1| 554|Homo sapiens organic cation transporter
protein.
Length = 554
Score = 156 bits (379), Expect = 2e-37
Identities = 127/537 (23%), Positives = 225/537 (41%), Gaps = 26/537 (4%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD--- 90
D++L GE G +Q F + +F+ +P+H C P +A L+
Sbjct: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGF-TPDHHCQSPGVAELSQRCG 63
Query: 91 ---TERRTLAIP-IDDSTKFGYSHCQVYDANWDEVLIAGQIP-------NSTWPTKACEH 139
E +P + + + C+ Y+ +W++ ++ P S P C+
Sbjct: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + + P +I +E + +C Q+ G G +G+ ADR+GR +
Sbjct: 124 GWVY---DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFFFGSLGVGYFADRFGRKLCLL 180
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ L+ + G+L F+ N+ ++R + G+ M Y ++ E+V + VA M
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM- 239
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + +T +A+ ++ A HW+ + + S C+PESPRWLLS R EAI
Sbjct: 240 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIR-RTFILMCLEFTC 378
+ I++ N + T++ S S ++F+ P +R RTFILM L FT
Sbjct: 300 KIMDHIAQKN--GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT- 356
Query: 379 CTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVF 438
++++ L+ G E+P + +D +GR + +L
Sbjct: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Query: 439 TLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIG 496
L+ +F+ + +++ + R + I+ AE+ PT VR G V IG
Sbjct: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG 476
Query: 497 TALSPYIVY-LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSR 552
++P+IV+ L+ LP LPET +P+T +AE L R
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGR 533
>BC126364-1|AAI26365.1| 554|Homo sapiens solute carrier family 22
(organic cation transporter), member 1 protein.
Length = 554
Score = 156 bits (379), Expect = 2e-37
Identities = 127/537 (23%), Positives = 225/537 (41%), Gaps = 26/537 (4%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD--- 90
D++L GE G +Q F + +F+ +P+H C P +A L+
Sbjct: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGF-TPDHHCQSPGVAELSQRCG 63
Query: 91 ---TERRTLAIP-IDDSTKFGYSHCQVYDANWDEVLIAGQIP-------NSTWPTKACEH 139
E +P + + + C+ Y+ +W++ ++ P S P C+
Sbjct: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + + P +I +E + +C Q+ G G +G+ ADR+GR +
Sbjct: 124 GWVY---DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFFFGSLGVGYFADRFGRKLCLL 180
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ L+ + G+L F+ N+ ++R + G+ M Y ++ E+V + VA M
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM- 239
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + +T +A+ ++ A HW+ + + S C+PESPRWLLS R EAI
Sbjct: 240 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIR-RTFILMCLEFTC 378
+ I++ N + T++ S S ++F+ P +R RTFILM L FT
Sbjct: 300 KIMDHIAQKN--GKLPPADLKMLSLEEDVTEKLSPSFADLFRTPRLRKRTFILMYLWFT- 356
Query: 379 CTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVF 438
++++ L+ G E+P + +D +GR + +L
Sbjct: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Query: 439 TLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIG 496
L+ +F+ + +++ + R + I+ AE+ PT VR G V IG
Sbjct: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG 476
Query: 497 TALSPYIVY-LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSR 552
++P+IV+ L+ LP LPET +P+T +AE L R
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGR 533
>BC033682-1|AAH33682.1| 550|Homo sapiens solute carrier family 22
(organic anion transporter), member 6 protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AJ249369-1|CAB77184.1| 563|Homo sapiens organic anion transporter
protein.
Length = 563
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AJ243995-1|CAB95971.1| 554|Homo sapiens protein ( Homo sapiens
partial oct1 gene for organic cation transporter, exon 1
and joined CDS. ).
Length = 554
Score = 153 bits (371), Expect = 2e-36
Identities = 126/537 (23%), Positives = 225/537 (41%), Gaps = 26/537 (4%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD--- 90
D++L GE G +Q F + +F+ +P+H C P +A L+
Sbjct: 5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGF-TPDHHCQSPGVAELSQRCG 63
Query: 91 ---TERRTLAIP-IDDSTKFGYSHCQVYDANWDEVLIAGQIP-------NSTWPTKACEH 139
E +P + + + C+ Y+ +W++ ++ P S P C+
Sbjct: 64 WSPAEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQD 123
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + + P +I +E + +C Q+ G + G +G+ ADR+GR +
Sbjct: 124 GWVY---DTPGSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLL 180
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ L+ + G+L F+ N+ ++R + G+ M Y ++ E+V + VA M
Sbjct: 181 GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIM- 239
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + +T +A+ ++ A HW+ + + S C+PESPRWLLS R EAI
Sbjct: 240 YQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAI 299
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIR-RTFILMCLEFTC 378
+ I++ N + T++ S S ++F+ +R RTFILM L FT
Sbjct: 300 KIMDHIAQKN--GKLPPADLKMLSLEEDVTEKLSPSFADLFRTLRLRKRTFILMYLWFT- 356
Query: 379 CTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVF 438
++++ L+ G E+P + +D +GR + +L
Sbjct: 357 DSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAA 416
Query: 439 TLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIG 496
L+ +F+ + +++ + R + I+ AE+ PT VR G V IG
Sbjct: 417 CLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIG 476
Query: 497 TALSPYIVY-LQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSR 552
++P+IV+ L+ LP LPET +P+T +AE L R
Sbjct: 477 GIITPFIVFRLREVWQALPLILFAVLGLLAAGVTLLLPETKGVALPETMKDAENLGR 533
>AF124373-1|AAD55356.1| 550|Homo sapiens organic anion transporter
1 protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AF097490-1|AAD19356.1| 550|Homo sapiens organic anion transporter
1 protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AF057039-1|AAC70004.1| 550|Homo sapiens putative renal organic
anion transporter 1 protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AB009698-1|BAA75073.1| 550|Homo sapiens hOAT1-2 protein.
Length = 550
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AB009697-1|BAA75072.1| 563|Homo sapiens hOAT1-1 protein.
Length = 563
Score = 153 bits (371), Expect = 2e-36
Identities = 114/524 (21%), Positives = 214/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AB291606-1|BAF45812.1| 581|Homo sapiens organic cation transporter
2 splice variant protein.
Length = 581
Score = 152 bits (368), Expect = 4e-36
Identities = 126/548 (22%), Positives = 232/548 (42%), Gaps = 36/548 (6%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE+ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIA-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R T+ + + D + +S C+ Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNHTVPLRLRDGREVPHS-CRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMD----------------------W--ICDRGSYQATAQALFFVGSII 180
+ ++ TI +E D W +C+ +LFFVG ++
Sbjct: 121 Q-DVYLSTIVTEQDSGAYNAMKNRMGKKPALCLPAQWNLVCEDDWKAPLTISLFFVGVLL 179
Query: 181 GGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAY 240
G F+ G ++DR+GR + + L F++NF F + + GM + + A+
Sbjct: 180 GSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAF 239
Query: 241 LILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXC 300
++ E + + + + + +FY + +P + W+ + + +
Sbjct: 240 VLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWW 299
Query: 301 CIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIF 360
IPESPRWL+S GR EEA I ++ N + K++SH+ L++
Sbjct: 300 FIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLL 359
Query: 361 KRPPIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMD 420
+ IR I+ + + ++ + L T L E+P+ + ++
Sbjct: 360 RTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQ 419
Query: 421 WMGRKWVTIGCMMLCSVFTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLP 478
++ R++ + L L V + + + ++ +F V +++ +TAE+ P
Sbjct: 420 YLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYP 479
Query: 479 TQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKK 538
T VR G V +G+ LSPY VYL Y +LP LPE+
Sbjct: 480 TVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGT 539
Query: 539 DIPQTFNE 546
+P T ++
Sbjct: 540 PLPDTIDQ 547
>AF104038-1|AAD10052.1| 550|Homo sapiens para-aminohippurate
transporter protein.
Length = 550
Score = 151 bits (365), Expect = 9e-36
Identities = 113/524 (21%), Positives = 213/524 (40%), Gaps = 14/524 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVSRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYI-V 504
+ VL + + S+N +T E+ PT +R +G + +G+ +SP + +
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSM 477
Query: 505 YLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
++Y S +P LPET + +P T + E
Sbjct: 478 TAELYPS-MPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLE 520
>AK222869-1|BAD96589.1| 550|Homo sapiens solute carrier family 22
member 11 variant protein.
Length = 550
Score = 148 bits (359), Expect = 5e-35
Identities = 120/535 (22%), Positives = 219/535 (40%), Gaps = 28/535 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS---PNHWCWVPELAN-- 87
F +LL AG G++Q L F+ + SQM + S P H CW L N
Sbjct: 3 FSKLLEQAGGVGLFQTLQVLT----FILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGS 58
Query: 88 ---LTDTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
T + L I I G C+ + W L+ ++W T+ C G
Sbjct: 59 AVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 116
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ TI ++ D +C + +Q++F G ++G F+ G ++ R+GR P +
Sbjct: 117 WVYDRSVFT-STIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G T FA F + RF+A + + +++E+ T + + +
Sbjct: 176 CCLQSAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F ++ A+ ++ A W+T+ + S +PES RWL+ G+ ++A+
Sbjct: 236 CAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQ 294
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLEIFKRPPIR-RTFILMCLEF 376
++ ++RIN + KE + +E S L++F P +R R+ ++ + F
Sbjct: 295 ELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNF 354
Query: 377 TCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCS 436
+ I + LV LG + A ++ ++GR+ + G +
Sbjct: 355 S-LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAG 413
Query: 437 VFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY 494
+ L + V + + V+ VL + IS + AE+ PT VR + ++H G
Sbjct: 414 LAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGR 473
Query: 495 IGTALSPYIVYLQIYISWL-PXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+G + P I+ + + L P LPET +P T + E
Sbjct: 474 LGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
>BC034384-1|AAH34384.1| 550|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 11 protein.
Length = 550
Score = 146 bits (355), Expect = 1e-34
Identities = 120/535 (22%), Positives = 219/535 (40%), Gaps = 28/535 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS---PNHWCWVPELAN-- 87
F +LL AG G++Q L F+ + SQM + S P H CW L N
Sbjct: 3 FSKLLEQAGGVGLFQTLQVLT----FILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGS 58
Query: 88 ---LTDTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
T + L I I G C+ + W L+ ++W T+ C G
Sbjct: 59 AVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 116
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ TI ++ D +C + +Q++F G ++G F+ G ++ R+GR P +
Sbjct: 117 WVYDRSVFT-STIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G T FA F + RF+A + + +++E+ T + + +
Sbjct: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F ++ A+ ++ A W+T+ + S +PES RWL+ G+ ++A+
Sbjct: 236 CAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQ 294
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLEIFKRPPIR-RTFILMCLEF 376
++ ++RIN + KE + +E S L++F P +R R+ ++ + F
Sbjct: 295 ELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNF 354
Query: 377 TCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCS 436
+ I + LV LG + A ++ ++GR+ + G +
Sbjct: 355 S-LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAG 413
Query: 437 VFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY 494
+ L + V + + V+ VL + IS + AE+ PT VR + ++H G
Sbjct: 414 LAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGR 473
Query: 495 IGTALSPYIVYLQIYISWL-PXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+G + P I+ + + L P LPET +P T + E
Sbjct: 474 LGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
>AC044790-3|AAK68155.1| 550|Homo sapiens OAT4 protein.
Length = 550
Score = 146 bits (355), Expect = 1e-34
Identities = 120/535 (22%), Positives = 219/535 (40%), Gaps = 28/535 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS---PNHWCWVPELAN-- 87
F +LL AG G++Q L F+ + SQM + S P H CW L N
Sbjct: 3 FSKLLEQAGGVGLFQTLQVLT----FILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGS 58
Query: 88 ---LTDTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
T + L I I G C+ + W L+ ++W T+ C G
Sbjct: 59 AVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 116
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ TI ++ D +C + +Q++F G ++G F+ G ++ R+GR P +
Sbjct: 117 WVYDRSVFT-STIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G T FA F + RF+A + + +++E+ T + + +
Sbjct: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F ++ A+ ++ A W+T+ + S +PES RWL+ G+ ++A+
Sbjct: 236 CAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQ 294
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLEIFKRPPIR-RTFILMCLEF 376
++ ++RIN + KE + +E S L++F P +R R+ ++ + F
Sbjct: 295 ELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNF 354
Query: 377 TCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCS 436
+ I + LV LG + A ++ ++GR+ + G +
Sbjct: 355 S-LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAG 413
Query: 437 VFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY 494
+ L + V + + V+ VL + IS + AE+ PT VR + ++H G
Sbjct: 414 LAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGR 473
Query: 495 IGTALSPYIVYLQIYISWL-PXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+G + P I+ + + L P LPET +P T + E
Sbjct: 474 LGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
>AB026116-1|BAA95316.1| 550|Homo sapiens organic anion transporter
4 protein.
Length = 550
Score = 146 bits (355), Expect = 1e-34
Identities = 120/535 (22%), Positives = 219/535 (40%), Gaps = 28/535 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS---PNHWCWVPELAN-- 87
F +LL AG G++Q L F+ + SQM + S P H CW L N
Sbjct: 3 FSKLLEQAGGVGLFQTLQVLT----FILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGS 58
Query: 88 ---LTDTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
T + L I I G C+ + W L+ ++W T+ C G
Sbjct: 59 AVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 116
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ TI ++ D +C + +Q++F G ++G F+ G ++ R+GR P +
Sbjct: 117 WVYDRSVFT-STIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G T FA F + RF+A + + +++E+ T + + +
Sbjct: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F ++ A+ ++ A W+T+ + S +PES RWL+ G+ ++A+
Sbjct: 236 CAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQ 294
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLEIFKRPPIR-RTFILMCLEF 376
++ ++RIN + KE + +E S L++F P +R R+ ++ + F
Sbjct: 295 ELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVNF 354
Query: 377 TCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCS 436
+ I + LV LG + A ++ ++GR+ + G +
Sbjct: 355 S-LLISYYGLVFDLQSLGRDIFLLQALFGAVDFLGRATTALLLSFLGRRTIQAGSQAMAG 413
Query: 437 VFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGY 494
+ L + V + + V+ VL + IS + AE+ PT VR + ++H G
Sbjct: 414 LAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLTIYKAELFPTPVRMTADGILHTVGR 473
Query: 495 IGTALSPYIVYLQIYISWL-PXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+G + P I+ + + L P LPET +P T + E
Sbjct: 474 LGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVLFFLPETQGLPLPDTIQDLE 528
>AB042505-1|BAB47393.1| 542|Homo sapiens organic anion transporter
3 protein.
Length = 542
Score = 143 bits (347), Expect = 1e-33
Identities = 95/433 (21%), Positives = 185/433 (42%), Gaps = 13/433 (3%)
Query: 127 IPNSTWPT-KACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLI 185
+PN T + C GW +N T+ +I +E D +C+ + AQ++F G +IGG ++
Sbjct: 84 LPNDTQRAMEPCLDGWVYNSTK---DSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVL 140
Query: 186 GWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLE 245
G ++DR+GR P S L+ G F+ F + ++RF+ G + ++ +E
Sbjct: 141 GDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVE 200
Query: 246 YVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPES 305
+V + + +++ A YT +P ++ A W+ + + S PES
Sbjct: 201 WVPTRMRAIMST-ALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPES 259
Query: 306 PRWLLSMGRVEEAINKILTISRIN--XXXXXXXXXXRFKCTVSKETK--EESHSCLEIFK 361
RWL+ G+ EA+ + ++ N K + KE + ++ ++F+
Sbjct: 260 IRWLVLSGKSSEALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFR 319
Query: 362 RPPIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDW 421
P +RR + L + + +L + G ++P+ + + +
Sbjct: 320 IPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSY 379
Query: 422 MGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARF---FVNISYNATMQWTAEVLP 478
+GR ++L L FV + +V TVLA F ++ S++ +T+E+ P
Sbjct: 380 LGRHTTQAAALLLAGGAILALTFVPLDLQTVR-TVLAVFGKGCLSSSFSCLFLYTSELYP 438
Query: 479 TQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKK 538
T +R +G V ++ +G+ +SP + ++P LPET +
Sbjct: 439 TVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQ 498
Query: 539 DIPQTFNEAEELS 551
+P+T + E S
Sbjct: 499 PLPETIEDLENWS 511
>AB007448-1|BAA23356.1| 551|Homo sapiens OCTN1 protein.
Length = 551
Score = 142 bits (345), Expect = 2e-33
Identities = 118/530 (22%), Positives = 233/530 (43%), Gaps = 18/530 (3%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE++ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAG-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R ++ + + D + +S C Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNNSVPLRLRDGREVPHS-CSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ T+ +E + +C+ +LFFVG ++G F+ G ++DR+GR +++T+
Sbjct: 121 Q-DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGR-KNVLFATMA 178
Query: 205 GCLG-GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALF 263
G L F+ ++ F++ I GM + ++A+++ E + + + + + F
Sbjct: 179 VQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTF 238
Query: 264 YTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKIL 323
+ + +P + W+ + + + IPESPRWL+S R EA + I
Sbjct: 239 FAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQ 298
Query: 324 TISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIF 383
+++N + K++ L++F+ I I+ L + ++ +
Sbjct: 299 KAAKMNNTAVPAVIFDSVE--ELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGY 356
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLL-- 441
AL L E+P+ ++ + R+++ I ++ LL
Sbjct: 357 FALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYI-IAAVLFWGGGVLLFI 415
Query: 442 -TVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALS 500
V V S+ +L +F + +++ +TAE+ PT VR V +G+ ++
Sbjct: 416 QLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIA 475
Query: 501 PYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
PY VYL Y LP PE+ +P+T + +++
Sbjct: 476 PYFVYLGAYNRMLPYIVMGSLTVLIGIFTLFFPESLGMTLPETLEQMQKV 525
>Y09881-1|CAA71007.1| 551|Homo sapiens ergothioneine transporter
(ETT) protein.
Length = 551
Score = 142 bits (344), Expect = 3e-33
Identities = 118/530 (22%), Positives = 233/530 (43%), Gaps = 18/530 (3%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE++ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAG-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R ++ + + D + +S C Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNNSVPLRLRDGREVPHS-CSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ T+ +E + +C+ +LFFVG ++G F+ G ++DR+GR +++T+
Sbjct: 121 Q-DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGR-KNVLFATMA 178
Query: 205 GCLG-GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALF 263
G L F+ ++ F++ I GM + ++A+++ E + + + + + F
Sbjct: 179 VQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTF 238
Query: 264 YTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKIL 323
+ + +P + W+ + + + IPESPRWL+S R EA + I
Sbjct: 239 FAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQ 298
Query: 324 TISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIF 383
+++N + K++ L++F+ I I+ L + ++ +
Sbjct: 299 KAAKMNNIAVPAVIFDSVE--ELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGY 356
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLL-- 441
AL L E+P+ ++ + R+++ I ++ LL
Sbjct: 357 FALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYI-IAAVLFWGGGVLLFI 415
Query: 442 -TVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALS 500
V V S+ +L +F + +++ +TAE+ PT VR V +G+ ++
Sbjct: 416 QLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIA 475
Query: 501 PYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
PY VYL Y LP PE+ +P+T + +++
Sbjct: 476 PYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKV 525
>BC028313-1|AAH28313.1| 551|Homo sapiens solute carrier family 22
(organic cation transporter), member 4 protein.
Length = 551
Score = 142 bits (344), Expect = 3e-33
Identities = 118/530 (22%), Positives = 233/530 (43%), Gaps = 18/530 (3%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
++DE++ GE+G +Q L+FF S + F S +F+ +P H C VP+ ANL+
Sbjct: 3 DYDEVIAFLGEWGPFQRLIFFLLSASIIPNGFNGMSVVFLAG-TPEHRCRVPDAANLSSA 61
Query: 92 ERR-TLAIPIDDSTKFGYSHCQVYD----ANWDEV-LIAGQ-IPNSTWPTKACEHGWEFN 144
R ++ + + D + +S C Y AN+ + L G+ + ++C GWEF+
Sbjct: 62 WRNNSVPLRLRDGREVPHS-CSRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFS 120
Query: 145 KTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLI 204
+ ++ T+ +E + +C+ +LFFVG ++G F+ G ++DR+GR +++T+
Sbjct: 121 Q-DVYLSTVVTEWNLVCEDNWKVPLTTSLFFVGVLLGSFVSGQLSDRFGR-KNVLFATMA 178
Query: 205 GCLG-GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALF 263
G L F+ ++ F++ I GM + ++A+++ E + + + + + F
Sbjct: 179 VQTGFSFLQIFSISWEMFTVLFVIVGMGQISNYVVAFILGTEILGKSVRIIFSTLGVCTF 238
Query: 264 YTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKIL 323
+ + +P + W+ + + + IPESPRWL+S R EA + I
Sbjct: 239 FAVGYMLLPLFAYFIRDWRMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQ 298
Query: 324 TISRINXXXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIF 383
+++N + K++ L++F+ I I+ L + ++ +
Sbjct: 299 KAAKMNNIAVPAVIFDSVE--ELNPLKQQKAFILDLFRTRNIAIMTIMSLLLWMLTSVGY 356
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLL-- 441
AL L E+P+ ++ + R+++ I ++ LL
Sbjct: 357 FALSLDAPNLHGDAYLNCFLSALIEIPAYITAWLLLRTLPRRYI-IAAVLFWGGGVLLFI 415
Query: 442 -TVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALS 500
V V S+ +L +F + +++ +TAE+ PT VR V +G+ ++
Sbjct: 416 QLVPVDYYFLSIGLVMLGKFGITSAFSMLYVFTAELYPTLVRNMAVGVTSTASRVGSIIA 475
Query: 501 PYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
PY VYL Y LP PE+ +P+T + +++
Sbjct: 476 PYFVYLGAYNRMLPYIVMGSLTVLIGILTLFFPESLGMTLPETLEQMQKV 525
>AY145501-1|AAN52927.1| 547|Homo sapiens putative transmembrane
transporter FLIPT 1 protein.
Length = 547
Score = 142 bits (344), Expect = 3e-33
Identities = 105/419 (25%), Positives = 187/419 (44%), Gaps = 29/419 (6%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
+ W+T++I+ + IPESPRWL S GR+ EA + I++ N
Sbjct: 213 QYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN 272
Query: 330 XXXXXXXXXXRFKCTVS-----KETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIF 383
+ KCT S + E+ S L++F+ R + T ILM + F C++++
Sbjct: 273 ---------RKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFV-CSLVY 322
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPS--MCVVAFIMDWMGRKWVTIGCMMLCSVFTLL 441
L S G LG E+PS +C+ W GRK + L + L+
Sbjct: 323 YGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLI 382
Query: 442 TVFV----GSGVPSVM----CTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+F+ +GV +V+ ++L + ++ ++N +T+E+ PT +R G +
Sbjct: 383 VMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFS 442
Query: 494 YIGTALSPYIVYLQIYISW-LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELS 551
+G ++P+I L+ Y+ W LP LPET + +TF++ + S
Sbjct: 443 RVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYS 500
>AL365318-2|CAH70686.1| 547|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 547
Score = 142 bits (344), Expect = 3e-33
Identities = 105/419 (25%), Positives = 187/419 (44%), Gaps = 29/419 (6%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
+ W+T++I+ + IPESPRWL S GR+ EA + I++ N
Sbjct: 213 QYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN 272
Query: 330 XXXXXXXXXXRFKCTVS-----KETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIF 383
+ KCT S + E+ S L++F+ R + T ILM + F C++++
Sbjct: 273 ---------RKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFV-CSLVY 322
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPS--MCVVAFIMDWMGRKWVTIGCMMLCSVFTLL 441
L S G LG E+PS +C+ W GRK + L + L+
Sbjct: 323 YGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLI 382
Query: 442 TVFV----GSGVPSVM----CTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+F+ +GV +V+ ++L + ++ ++N +T+E+ PT +R G +
Sbjct: 383 VMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFS 442
Query: 494 YIGTALSPYIVYLQIYISW-LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELS 551
+G ++P+I L+ Y+ W LP LPET + +TF++ + S
Sbjct: 443 RVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYS 500
>AL357137-2|CAH70380.1| 547|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 547
Score = 142 bits (344), Expect = 3e-33
Identities = 105/419 (25%), Positives = 187/419 (44%), Gaps = 29/419 (6%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
+ W+T++I+ + IPESPRWL S GR+ EA + I++ N
Sbjct: 213 QYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN 272
Query: 330 XXXXXXXXXXRFKCTVS-----KETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIF 383
+ KCT S + E+ S L++F+ R + T ILM + F C++++
Sbjct: 273 ---------RKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFV-CSLVY 322
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPS--MCVVAFIMDWMGRKWVTIGCMMLCSVFTLL 441
L S G LG E+PS +C+ W GRK + L + L+
Sbjct: 323 YGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLI 382
Query: 442 TVFV----GSGVPSVM----CTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+F+ +GV +V+ ++L + ++ ++N +T+E+ PT +R G +
Sbjct: 383 VMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFS 442
Query: 494 YIGTALSPYIVYLQIYISW-LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELS 551
+G ++P+I L+ Y+ W LP LPET + +TF++ + S
Sbjct: 443 RVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYS 500
>BC022387-1|AAH22387.1| 542|Homo sapiens solute carrier family 22
(organic anion transporter), member 8 protein.
Length = 542
Score = 142 bits (343), Expect = 4e-33
Identities = 94/433 (21%), Positives = 185/433 (42%), Gaps = 13/433 (3%)
Query: 127 IPNSTWPT-KACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLI 185
+PN T + C GW +N T+ +I +E D +C+ + AQ++F G +IGG ++
Sbjct: 84 LPNDTQRAMEPCLDGWVYNSTK---DSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVL 140
Query: 186 GWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLE 245
G ++DR+GR P S L+ G F+ F + ++RF+ G + ++ +E
Sbjct: 141 GDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVE 200
Query: 246 YVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPES 305
+V + + +++ A YT +P ++ A W+ + + S PES
Sbjct: 201 WVPTRMRAIMST-ALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPES 259
Query: 306 PRWLLSMGRVEEAINKILTISRIN--XXXXXXXXXXRFKCTVSKETK--EESHSCLEIFK 361
RWL+ G+ +A+ + ++ N K + KE + ++ ++F+
Sbjct: 260 IRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEISLAKAKYTASDLFR 319
Query: 362 RPPIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDW 421
P +RR + L + + +L + G ++P+ + + +
Sbjct: 320 IPMLRRMTFCLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSY 379
Query: 422 MGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARF---FVNISYNATMQWTAEVLP 478
+GR ++L L FV + +V TVLA F ++ S++ +T+E+ P
Sbjct: 380 LGRHTTQAAALLLAGGAILALTFVPLDLQTVR-TVLAVFGKGCLSSSFSCLFLYTSELYP 438
Query: 479 TQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKK 538
T +R +G V ++ +G+ +SP + ++P LPET +
Sbjct: 439 TVIRQTGMGVSNLWTRVGSMVSPLVKITGEVQPFIPNIIYGITALLGGSAALFLPETLNQ 498
Query: 539 DIPQTFNEAEELS 551
+P+T + E S
Sbjct: 499 PLPETIEDLENWS 511
>AL583834-4|CAI14464.1| 546|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 546
Score = 139 bits (337), Expect = 2e-32
Identities = 120/542 (22%), Positives = 230/542 (42%), Gaps = 20/542 (3%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYS 201
E++ +E TI +E D +C++ A FF G ++G G+++DR+GR + +
Sbjct: 118 EYDHSEFS-STIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA 176
Query: 202 TLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
+ + G+ + + ++ F+I R + G A ++ + LE++ +++T VA + +
Sbjct: 177 YVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVLSS 235
Query: 262 LFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINK 321
F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY 295
Query: 322 ILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCC 379
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV 355
Query: 380 TIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFT 439
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF 415
Query: 440 LLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGT 497
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +G
Sbjct: 416 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG 475
Query: 498 ALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSRNINL 556
+L+P L +++S LP LPET + +P+T + E S +L
Sbjct: 476 SLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSL 534
Query: 557 WE 558
E
Sbjct: 535 QE 536
>BC026358-1|AAH26358.1| 535|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 535
Score = 139 bits (336), Expect = 3e-32
Identities = 104/419 (24%), Positives = 186/419 (44%), Gaps = 29/419 (6%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 82 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 141
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 142 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 200
Query: 270 AMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
+ W+T++I+ + IPESPRWL S GR+ EA + I++ N
Sbjct: 201 QYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRN 260
Query: 330 XXXXXXXXXXRFKCTVS-----KETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIF 383
+ KCT S + E+ S L++F+ R + T ILM + F C++++
Sbjct: 261 ---------RKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFV-CSLVY 310
Query: 384 DALVRSTGQLGXXXXXXXXXXXXTELPS--MCVVAFIMDWMGRKWVTIGCMMLCSVFTLL 441
L S G LG E+ S +C+ W GRK + L + L+
Sbjct: 311 YGLTLSAGDLGGSIYANLALSGLIEIQSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLI 370
Query: 442 TVFV----GSGVPSVM----CTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+F+ +GV +V+ ++L + ++ ++N +T+E+ PT +R G +
Sbjct: 371 VMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFS 430
Query: 494 YIGTALSPYIVYLQIYISW-LPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELS 551
+G ++P+I L+ Y+ W LP LPET + +TF++ + S
Sbjct: 431 RVGGIIAPFIPSLK-YVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYS 488
>AB075951-1|BAC02720.1| 483|Homo sapiens organic cation transporter
hOCT2-A protein.
Length = 483
Score = 138 bits (335), Expect = 4e-32
Identities = 105/431 (24%), Positives = 189/431 (43%), Gaps = 25/431 (5%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLT---- 89
D++L GEF +Q +FF + +Y +F+ +P+H C P +A L+
Sbjct: 6 DDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGF-TPDHRCRSPGVAELSLRCG 64
Query: 90 --DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV-------LIAGQIPNSTWPTKACEH 139
E +P + + C+ Y+ +W++ L + S P C
Sbjct: 65 WSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRD 124
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + E P +I +E + +C Q+ VG IG IG++ADR+GR +
Sbjct: 125 GWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLL 181
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ LI G+L + +T I+R I G+ ++ Y+++ E+V +Y+ V +
Sbjct: 182 TTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYILITEFVGRRYRRTV-GIF 240
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ + YT + + ++ A HW+ + + CIPESPRWL+S + EA+
Sbjct: 241 YQVAYTVGLLVLAGVAYALPHWRWLQFTVALPNFFFLLYYWCIPESPRWLISQNKNAEAM 300
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKET-KEESHSCLEIFKRPPIRR-TFILMCLEFT 377
I I++ N + + +ET K+ + S L++ + P IR+ T ILM FT
Sbjct: 301 RIIKHIAKKNGKSLPASLQ---RLRLEEETGKKLNPSFLDLVRTPQIRKHTMILMYNWFT 357
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
++++ L+ G G E P+ ++ +D +GR++ M+
Sbjct: 358 -SSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIGRRYPWAASNMVAGA 416
Query: 438 FTLLTVFVGSG 448
L +VF+ G
Sbjct: 417 ACLASVFIPGG 427
>BC033805-1|AAH33805.1| 548|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 548
Score = 137 bits (331), Expect = 1e-31
Identities = 120/544 (22%), Positives = 230/544 (42%), Gaps = 22/544 (4%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDW--ICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
E++ +E TI +E W +C++ A FF G ++G G+++DR+GR +
Sbjct: 118 EYDHSEFS-STIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLL 176
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ + + G+ + + ++ F+I R + G A ++ + LE++ +++T VA +
Sbjct: 177 VAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVL 235
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH 295
Query: 320 NKILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFT 377
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF 355
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL 415
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYI 495
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +
Sbjct: 416 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL 475
Query: 496 GTALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSRNI 554
G +L+P L +++S LP LPET + +P+T + E S
Sbjct: 476 GGSLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPT 534
Query: 555 NLWE 558
+L E
Sbjct: 535 SLQE 538
>AY050498-1|AAL12496.1| 548|Homo sapiens organic anion transporter
2 protein.
Length = 548
Score = 137 bits (331), Expect = 1e-31
Identities = 120/544 (22%), Positives = 230/544 (42%), Gaps = 22/544 (4%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDW--ICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
E++ +E TI +E W +C++ A FF G ++G G+++DR+GR +
Sbjct: 118 EYDHSEFS-STIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLL 176
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ + + G+ + + ++ F+I R + G A ++ + LE++ +++T VA +
Sbjct: 177 VAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVL 235
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH 295
Query: 320 NKILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFT 377
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF 355
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL 415
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYI 495
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +
Sbjct: 416 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL 475
Query: 496 GTALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSRNI 554
G +L+P L +++S LP LPET + +P+T + E S
Sbjct: 476 GGSLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPT 534
Query: 555 NLWE 558
+L E
Sbjct: 535 SLQE 538
>AL583834-5|CAI14463.1| 548|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 548
Score = 137 bits (331), Expect = 1e-31
Identities = 120/544 (22%), Positives = 230/544 (42%), Gaps = 22/544 (4%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDW--ICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
E++ +E TI +E W +C++ A FF G ++G G+++DR+GR +
Sbjct: 118 EYDHSEFS-STIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLL 176
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ + + G+ + + ++ F+I R + G A ++ + LE++ +++T VA +
Sbjct: 177 VAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVL 235
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH 295
Query: 320 NKILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFT 377
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF 355
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL 415
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYI 495
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +
Sbjct: 416 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL 475
Query: 496 GTALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSRNI 554
G +L+P L +++S LP LPET + +P+T + E S
Sbjct: 476 GGSLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPT 534
Query: 555 NLWE 558
+L E
Sbjct: 535 SLQE 538
>AL583834-3|CAI14462.1| 539|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 539
Score = 137 bits (331), Expect = 1e-31
Identities = 117/532 (21%), Positives = 226/532 (42%), Gaps = 20/532 (3%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYS 201
E++ +E TI +E D +C++ A FF G ++G G+++DR+GR + +
Sbjct: 118 EYDHSEFS-STIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA 176
Query: 202 TLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
+ + G+ + + ++ F+I R + G A ++ + LE++ +++T VA + +
Sbjct: 177 YVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVLSS 235
Query: 262 LFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINK 321
F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY 295
Query: 322 ILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCC 379
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 LLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV 355
Query: 380 TIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFT 439
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAF 415
Query: 440 LLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGT 497
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +G
Sbjct: 416 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG 475
Query: 498 ALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+L+P L +++S LP LPET + +P+T + E
Sbjct: 476 SLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVE 526
>AF097518-1|AAD37091.1| 548|Homo sapiens liver-specific transporter
protein.
Length = 548
Score = 137 bits (331), Expect = 1e-31
Identities = 120/544 (22%), Positives = 230/544 (42%), Gaps = 22/544 (4%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDW--ICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
E++ +E TI +E W +C++ A FF G ++G G+++DR+GR +
Sbjct: 118 EYDHSEFS-STIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLL 176
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+ + + G+ + + ++ F+I R + G A ++ + LE++ +++T VA +
Sbjct: 177 VAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVL 235
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
+ F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 SSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAH 295
Query: 320 NKILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFT 377
+L +R+N + + E S L++F+ P +R + + +
Sbjct: 296 RYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWF 355
Query: 378 CCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSV 437
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 GVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTAL 415
Query: 438 FTLLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYI 495
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +
Sbjct: 416 AFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRL 475
Query: 496 GTALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEELSRNI 554
G +L+P L +++S LP LPET + +P+T + E S
Sbjct: 476 GGSLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPT 534
Query: 555 NLWE 558
+L E
Sbjct: 535 SLQE 538
>AJ271205-1|CAB97249.1| 519|Homo sapiens putative organic anion
transporter protein.
Length = 519
Score = 136 bits (329), Expect = 2e-31
Identities = 100/457 (21%), Positives = 187/457 (40%), Gaps = 12/457 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVR 482
+ VL + + S+N +T E+ PT +R
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR 454
>AJ251529-1|CAB94830.1| 506|Homo sapiens putative organic anion
transporter protein.
Length = 506
Score = 136 bits (329), Expect = 2e-31
Identities = 100/457 (21%), Positives = 187/457 (40%), Gaps = 12/457 (2%)
Query: 33 FDELLIAAGEFGIYQ-ILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDT 91
F++LL G G +Q I + P L + + T P H C P ANL+
Sbjct: 3 FNDLLQQVGGVGRFQQIQVTLVVLPLLLMAS--HNTLQNFTAAIPTHHCRPPADANLSKN 60
Query: 92 ERRTLAIPIDDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEIPYP 151
+ +P D + S + W + G N T T+ C GW ++ + P
Sbjct: 61 GGLEVWLPRDRQGQ-PESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFP-S 118
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
TI +E D +C + + AQ+L+ VG ++G + G++ADR GR + + L + G
Sbjct: 119 TIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTC 178
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA NF + +R ++GMA + + +E++ P + Y+ +
Sbjct: 179 AAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWM-PIHTRACVGTLIGYVYSLGQFLL 237
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXX 331
++ A HW+ + ++ S ES RW S GR++ + + ++RIN
Sbjct: 238 AGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGK 297
Query: 332 XXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALV 387
+ ++ KE + S +E+ + P +R F+ + + + + + LV
Sbjct: 298 REEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLV 357
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV-- 445
G +LP+ V +++ +GR+ + ++L + LL +
Sbjct: 358 MDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQ 417
Query: 446 GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVR 482
+ VL + + S+N +T E+ PT +R
Sbjct: 418 DQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIR 454
>AF210455-1|AAG43523.1| 539|Homo sapiens organic anion transporter
2 protein.
Length = 539
Score = 135 bits (327), Expect = 4e-31
Identities = 117/532 (21%), Positives = 225/532 (42%), Gaps = 20/532 (3%)
Query: 31 INFDELLIAAGEFGIYQIL-LFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPEL-ANL 88
+ F+ELL G FG +Q+ + P L + + +F+ P H C +P AN
Sbjct: 1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLH-FLLPIFLAAV-PAHRCALPGAPANF 58
Query: 89 TDTERRTLA-IPID-DST-----KFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHGW 141
+ + A +P + D T +F Y +E G++ + T C GW
Sbjct: 59 SHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEP-ATVPCSQGW 117
Query: 142 EFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYS 201
E++ +E TI +E D +C++ A FF G ++G G+++DR+GR + +
Sbjct: 118 EYDHSEFS-STIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA 176
Query: 202 TLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
+ + G+ + + ++ F+I R + G A ++ + LE++ +++T VA + +
Sbjct: 177 YVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRT-VAGVLSS 235
Query: 262 LFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINK 321
F+T + + + W+ + + + +PES RWLL+ G V+EA
Sbjct: 236 TFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRY 295
Query: 322 ILTISRINXXXXXXXXXXR--FKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCC 379
+L +R N + + E S L++F+ P +R + + +
Sbjct: 296 LLHCARPNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGV 355
Query: 380 TIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFT 439
+ L LG ELPS +V + + GR+ G ++ ++
Sbjct: 356 NFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGAALAF 415
Query: 440 LLTVFVGSGVP--SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGT 497
+ V S + S + V+ + F ++ +T+E+ PT +R +G + + G +G
Sbjct: 416 GTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGG 475
Query: 498 ALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
+L+P L +++S LP LPET + +P+T + E
Sbjct: 476 SLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVE 526
>BC101316-1|AAI01317.1| 547|Homo sapiens LOC387601 protein protein.
Length = 547
Score = 130 bits (314), Expect = 1e-29
Identities = 121/536 (22%), Positives = 215/536 (40%), Gaps = 27/536 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS--PNHWCWVPELANLT- 89
F +LL G G +QIL +F V VY+ + +H CWV L N T
Sbjct: 3 FQDLLDQVGGLGRFQILQMVF---LIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTI 59
Query: 90 -DTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKACE 138
D + TL+ IP D + + C+ + W + + G PN++ P T+ C
Sbjct: 60 PDNDPGTLSQDALLRISIPFDSNLR--PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCV 117
Query: 139 HGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAA 198
GW ++++ P TI ++ D +C+ + A+ LF G ++GG L G ++DR+GR
Sbjct: 118 DGWVYDQSSFP-STIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVL 176
Query: 199 VYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANM 258
+S L + G FA + RF+AG A + ++ L+++E++T ++ M +
Sbjct: 177 RWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTL 236
Query: 259 AFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
I + ++ + +V S + ES RWL+ + EE
Sbjct: 237 TLCAASIGH-ITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEG 295
Query: 319 INKILTISRINXXXXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCL 374
+ ++ + N K T+ +E + ++ HS E+ + P I + +
Sbjct: 296 LKELTKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSF 355
Query: 375 EFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMML 434
TI F L LG L + CV + ++ M R+ + M L
Sbjct: 356 VRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFL 415
Query: 435 CSVFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHIC 492
+ L +FV + + V+ L ++ + E++P+ +RG +
Sbjct: 416 LATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNF 475
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
IG AL+ ++ L IY LP LPET + + + + E
Sbjct: 476 ANIGGALASLVMILSIYSRPLPWIIYGVFAILSGLVVLLLPETRNQPLLDSIQDVE 531
>AB026898-3|BAA77626.1| 594|Homo sapiens organic-cation transporter
like 4 protein.
Length = 594
Score = 130 bits (314), Expect = 1e-29
Identities = 121/544 (22%), Positives = 218/544 (40%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSTIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+ +
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVWA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP LPET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>AB011082-1|BAA76351.1| 594|Homo sapiens organic-cation transporter
like 4 protein.
Length = 594
Score = 130 bits (314), Expect = 1e-29
Identities = 121/544 (22%), Positives = 218/544 (40%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSTIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+ +
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVWA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP LPET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>AY437532-1|AAR84082.1| 547|Homo sapiens putative UST1-like organic
anion transporter protein.
Length = 547
Score = 129 bits (312), Expect = 2e-29
Identities = 121/536 (22%), Positives = 215/536 (40%), Gaps = 27/536 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS--PNHWCWVPELANLT- 89
F +LL G G +QIL +F V VY+ + +H CWV L N T
Sbjct: 3 FQDLLDQVGGLGRFQILQMVF---LIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTI 59
Query: 90 -DTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKACE 138
D + TL+ IP D + + C+ + W + + G PN++ P T+ C
Sbjct: 60 PDNDPGTLSQDALLRISIPFDSNLR--PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCV 117
Query: 139 HGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAA 198
GW ++++ P TI ++ D +C+ + A+ LF G ++GG L G ++DR+GR
Sbjct: 118 DGWVYDQSSFP-STIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVL 176
Query: 199 VYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANM 258
+S L + G FA + RF+AG A + ++ L+++E++T ++ M +
Sbjct: 177 RWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTL 236
Query: 259 AFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
I + ++ + +V S + ES RWL+ + EE
Sbjct: 237 TLCAASIGH-ITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEG 295
Query: 319 INKILTISRINXXXXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPIRRTFILMCL 374
+ ++ + N K T+ +E + ++ HS E+ + P I + +
Sbjct: 296 LKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNICKRICFLSF 355
Query: 375 EFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMML 434
TI F L LG L + CV + ++ M R+ + M L
Sbjct: 356 VRFASTIPFWGLTLHLQHLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRRLSQMLLMFL 415
Query: 435 CSVFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHIC 492
+ L +FV + + V+ L ++ + E++P+ +RG +
Sbjct: 416 LATCLLAIIFVPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNF 475
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
IG AL+ ++ L IY LP LPET + + + + E
Sbjct: 476 ANIGGALASLVMILSIYSRPLPWIIYGVFAILSGLVVLLLPETRNQPLLDSIQDVE 531
>BC130543-1|AAI30544.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 128 bits (308), Expect = 7e-29
Identities = 121/544 (22%), Positives = 217/544 (39%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSIIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVGA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP LPET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>BC075071-1|AAH75071.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 128 bits (308), Expect = 7e-29
Identities = 121/544 (22%), Positives = 217/544 (39%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSIIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVGA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP LPET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>BC075070-1|AAH75070.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 128 bits (308), Expect = 7e-29
Identities = 121/544 (22%), Positives = 217/544 (39%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSIIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVGA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP LPET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLPETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>BC126482-1|AAI26483.1| 594|Homo sapiens solute carrier family 22
(organic cation transporter), member 14 protein.
Length = 594
Score = 124 bits (299), Expect = 9e-28
Identities = 120/544 (22%), Positives = 216/544 (39%), Gaps = 36/544 (6%)
Query: 33 FDELLIAAGEFGIYQILLFFATS-PFFLFGVFVYYSQMFITEPSPN-HWCWVPELA-NLT 89
F LL A GEFG +Q L T P + F++ T P + W+ + +L+
Sbjct: 52 FANLLDAVGEFGTFQQRLVALTFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGPHLS 111
Query: 90 DTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWPTKACEHGWEFNKTEI 148
E+ L IP + + C +Y W+ + I T C+ GW + +
Sbjct: 112 KAEQLNLTIP--QAPNGSFLTCFMYLPVPWN---LDSIIQFGLNDTDTCQDGWIY--PDA 164
Query: 149 PYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLG 208
++ +E D +C + + TAQ +F G IG + + D+ GR PA + S L +
Sbjct: 165 KKRSLINEFDLVCGMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIF 224
Query: 209 GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFT 268
G T F +F + +RF + + + + E++ +++ + F+
Sbjct: 225 GFGTAFMNSFHLYLFFRFGISQSVVGYAISSISLATEWLVGEHRAHAIILGHC-FFAVGA 283
Query: 269 IAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRI 328
+ + I+ HW+ + +V +PESPRWL+ G+V+EA + + +
Sbjct: 284 MLLTGIAYGLPHWQLLFLVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASV 343
Query: 329 NXXXXXXXXXXRFKCTVSKETKEESHSCLEIFK-RPPIRRTFILMCLEFTCCTIIFDALV 387
N + K T+ S L+ K R + T ++ C+ FT F +
Sbjct: 344 NKKTIPSNLLDELQLPRKKVTRA---SVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSL 400
Query: 388 RSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS 447
R +LG E+P+ F++ +GRKW ++ ++ LL +F+
Sbjct: 401 RMR-ELGVSVHFRHVVPSIMEVPARLCCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPE 459
Query: 448 GVPSV-----MC--------TVLARFFVNISYNATMQ----WTAEVLPTQVRGSGASVVH 490
G + C T+L S AT+ +TAE+LPT +R +G +V
Sbjct: 460 GEDGLRLKWPRCPATELKSMTILVLMLREFSLAATVTVFFLYTAELLPTVLRATGLGLVS 519
Query: 491 ICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
+ G LS + + S LP L ET + + ++ N + ++
Sbjct: 520 LASVAGAILS--LTIISQTPSLLPIFLCCVLAIVAFSLSSLLRETRDQPLSESLNHSSQI 577
Query: 551 SRNI 554
+
Sbjct: 578 RNKV 581
>BC126288-1|AAI26289.1| 553|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 9 protein.
Length = 553
Score = 123 bits (296), Expect = 2e-27
Identities = 120/534 (22%), Positives = 216/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LPET K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>AK074246-1|BAB85030.1| 552|Homo sapiens protein ( Homo sapiens
cDNA FLJ23666 fis, clone HEP04439. ).
Length = 552
Score = 123 bits (296), Expect = 2e-27
Identities = 120/534 (22%), Positives = 216/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LPET K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>AJ295270-1|CAC82910.1| 553|Homo sapiens putative integral membrane
transport protein protein.
Length = 553
Score = 123 bits (296), Expect = 2e-27
Identities = 120/534 (22%), Positives = 216/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LPET K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>AF440402-1|AAP97316.1| 553|Homo sapiens putative integral membrane
transport protein protein.
Length = 553
Score = 123 bits (296), Expect = 2e-27
Identities = 120/534 (22%), Positives = 216/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LPET K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>AB074812-1|BAF51552.1| 553|Homo sapiens organic anion transporter
7 protein.
Length = 553
Score = 123 bits (296), Expect = 2e-27
Identities = 120/534 (22%), Positives = 216/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LPET K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530
>AB062418-1|BAB83517.1| 553|Homo sapiens hUST3 protein.
Length = 553
Score = 120 bits (289), Expect = 1e-26
Identities = 119/534 (22%), Positives = 215/534 (40%), Gaps = 26/534 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W +++ TI +E D +CD S + A+ +F G ++GG L G ++DR+GR +
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G A F + RF++G+A + + +++ E+ T +++ M +
Sbjct: 179 CYLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGM 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
+F + + ++ A W + +V S + ES RWL+ + EE +
Sbjct: 239 CPSGIAF-MTLAGLAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLK 297
Query: 321 KILTISRINXXXXXXXXXXR--FKCTVSKE---TKEESHSCLEIFKRPPIRRTFILMCLE 375
++ + + K T+ KE +++ S E+ P I + L+
Sbjct: 298 ELRKAAHRSGMKNARDTLTLEILKSTMKKELEAAQKKKPSLCEMLHMPNICKRISLLSFT 357
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ + L LG L + CV + + +M R+ + M L
Sbjct: 358 RFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLL 417
Query: 436 SVFTLLTVFVGSGVPSVMCTVLARFFVNISYNA-TMQWT--AEVLPTQVRGSGASVVHIC 492
++ L +FV + ++ VLA + S A T+ + EV+PT +R +
Sbjct: 418 AICLLAIIFVPQEMQTLR-EVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATF 476
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
I AL+P ++ L +Y LP LP T K + T +
Sbjct: 477 ANIAGALAPLMMILSVYSPPLPWIIYGVFPFISGFAFLLLPGTRNKPLFDTIQD 530
>BC053348-1|AAH53348.1| 553|Homo sapiens solute carrier family 22
(organic anion/cation transporter), member 12 protein.
Length = 553
Score = 113 bits (271), Expect = 2e-24
Identities = 110/535 (20%), Positives = 202/535 (37%), Gaps = 25/535 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
+ LAI I C+ + W L+ ++W T+ C G
Sbjct: 62 SILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ I TI ++ + +CD + + AQ+++ G ++G G +DR+GR +
Sbjct: 120 WVYDRS-IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S L + G FA F + ++RF+ A MM +L+E+ + + +V +
Sbjct: 179 SYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNS 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F + ++ W + +V S + ES RWLL+ GR++ +
Sbjct: 239 LGFSFGHGLTAA-VAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQ 297
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKETKEES-----HSCLEIFKRPPIRRTFILMCLE 375
++ ++ IN + +S +E S S + + P +R + L
Sbjct: 298 ELWRVAAINGKGAVQDTLTP-EVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLC 356
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ F L LG ++P+ ++ +GR+ ++L
Sbjct: 357 WFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLA 416
Query: 436 SVFTLLTVFV--GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+ L V G VL V ++ +++E+ PT +R + + +
Sbjct: 417 GLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAA 476
Query: 494 YIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
G L P + L ++ WLP LPET +P T + +
Sbjct: 477 RGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQ 531
>AC044790-2|AAK68156.1| 553|Homo sapiens RST protein.
Length = 553
Score = 113 bits (271), Expect = 2e-24
Identities = 110/535 (20%), Positives = 202/535 (37%), Gaps = 25/535 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
+ LAI I C+ + W L+ ++W T+ C G
Sbjct: 62 SILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ I TI ++ + +CD + + AQ+++ G ++G G +DR+GR +
Sbjct: 120 WVYDRS-IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S L + G FA F + ++RF+ A MM +L+E+ + + +V +
Sbjct: 179 SYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNS 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F + ++ W + +V S + ES RWLL+ GR++ +
Sbjct: 239 LGFSFGHGLTAA-VAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQ 297
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKETKEES-----HSCLEIFKRPPIRRTFILMCLE 375
++ ++ IN + +S +E S S + + P +R + L
Sbjct: 298 ELWRVAAINGKGAVQDTLTP-EVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLC 356
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ F L LG ++P+ ++ +GR+ ++L
Sbjct: 357 WFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLA 416
Query: 436 SVFTLLTVFV--GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+ L V G VL V ++ +++E+ PT +R + + +
Sbjct: 417 GLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAA 476
Query: 494 YIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
G L P + L ++ WLP LPET +P T + +
Sbjct: 477 RGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQ 531
>AB071863-1|BAB96750.1| 553|Homo sapiens URAT1 protein.
Length = 553
Score = 113 bits (271), Expect = 2e-24
Identities = 110/535 (20%), Positives = 202/535 (37%), Gaps = 25/535 (4%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
+ LAI I C+ + W L+ ++W T+ C G
Sbjct: 62 SILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ I TI ++ + +CD + + AQ+++ G ++G G +DR+GR +
Sbjct: 120 WVYDRS-IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S L + G FA F + ++RF+ A MM +L+E+ + + +V +
Sbjct: 179 SYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNS 238
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F + ++ W + +V S + ES RWLL+ GR++ +
Sbjct: 239 LGFSFGHGLTAA-VAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQ 297
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKETKEES-----HSCLEIFKRPPIRRTFILMCLE 375
++ ++ IN + +S +E S S + + P +R + L
Sbjct: 298 ELWRVAAINGKGAVQDTLTP-EVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLC 356
Query: 376 FTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLC 435
+ F L LG ++P+ ++ +GR+ ++L
Sbjct: 357 WFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLA 416
Query: 436 SVFTLLTVFV--GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICG 493
+ L V G VL V ++ +++E+ PT +R + + +
Sbjct: 417 GLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAA 476
Query: 494 YIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
G L P + L ++ WLP LPET +P T + +
Sbjct: 477 RGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQ 531
>AK129930-1|BAC85252.1| 442|Homo sapiens er 11 (SLC22A11).
protein.
Length = 442
Score = 112 bits (269), Expect = 4e-24
Identities = 88/378 (23%), Positives = 164/378 (43%), Gaps = 29/378 (7%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS---PNHWCWVPELAN-- 87
F +LL AG G++Q L F+ + SQM + S P H CW L N
Sbjct: 3 FSKLLEQAGGVGLFQTLQVLT----FILPCLMIPSQMLLENFSAAIPGHRCWTHMLDNGS 58
Query: 88 ---LTDTERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
T + L I I G C+ + W L+ ++W T+ C G
Sbjct: 59 AVSTNMTPKALLTISIPPGPNQGPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 116
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ TI ++ D +C + +Q++F G ++G F+ G ++ R+GR P +
Sbjct: 117 WVYDRSVFT-STIVAKWDLVCSSQGLKPLSQSIFMSGILVGSFIWGLLSYRFGRKPMLSW 175
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
L + G T FA F + RF+A + + +++E+ T + + +
Sbjct: 176 CCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIFLSSLTLMVEWTTTSRRAVTMTVVG 235
Query: 261 ALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAIN 320
F ++ A+ ++ A W+T+ + S +PES RWL+ G+ ++A+
Sbjct: 236 CAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWWLPESARWLIIKGKPDQALQ 294
Query: 321 KILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLEIFKRPPIR-RTFILMCLEF 376
++ ++RIN + KE + +E S L++F P +R R+ ++ ++
Sbjct: 295 ELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPVLRWRSCAMLVVKM 354
Query: 377 TCCTIIFDALVRSTGQLG 394
T D ++ + G+LG
Sbjct: 355 TA-----DGILHTVGRLG 367
>AK075224-1|BAC11483.1| 401|Homo sapiens protein ( Homo sapiens
cDNA FLJ90743 fis, clone PLACE1011236, weakly similar to
Mus musculus mRNA for RST. ).
Length = 401
Score = 112 bits (269), Expect = 4e-24
Identities = 82/379 (21%), Positives = 157/379 (41%), Gaps = 9/379 (2%)
Query: 177 GSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCM 236
G ++G F+ G ++ R+GR P + L + G T FA F + RF+A
Sbjct: 3 GILVGSFIWGLLSYRFGRKPMLSWCCLQLAVAGTSTIFAPTFVIYCGLRFVAAFGMAGIF 62
Query: 237 MMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXX 296
+ + +++E+ T + + + F ++ A+ ++ A W+T+ + S
Sbjct: 63 LSSLTLMVEWTTTSRRAVTMTVVGCAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAIS 121
Query: 297 XXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKE---TKEES 353
+PES RWL+ G+ ++A+ ++ ++RIN + KE + +E
Sbjct: 122 LISWWLPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEP 181
Query: 354 HSCLEIFKRPPIR-RTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSM 412
S L++F P +R R+ ++ + F+ I + LV LG +
Sbjct: 182 RSVLDLFCVPVLRWRSCAMLVVNFS-LLISYYGLVFDLQSLGRDIFRLQALFGAVDFLGR 240
Query: 413 CVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATM 470
A ++ ++GR+ + G + + L + V + + V+ VL + IS
Sbjct: 241 ATTALLLSFLGRRTIQAGSQAMAGLAILANMLVPQDLQTLRVVFAVLGKGCFGISLTCLT 300
Query: 471 QWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWL-PXXXXXXXXXXXXXXX 529
+ AE+ PT VR + ++H G +G + P I+ + + L P
Sbjct: 301 IYKAELFPTPVRMTADGILHTVGRLGAMMGPLILMSRQALPLLPPLLYGVISIASSLVVL 360
Query: 530 XXLPETTKKDIPQTFNEAE 548
LPET +P T + E
Sbjct: 361 FFLPETQGLPLPDTIQDLE 379
>AL162582-2|CAI20004.1| 334|Homo sapiens solute carrier family 22
(organic cation transporter), member 2 protein.
Length = 334
Score = 110 bits (264), Expect = 2e-23
Identities = 81/314 (25%), Positives = 141/314 (44%), Gaps = 23/314 (7%)
Query: 75 SPNHWCWVPELANLT------DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV------ 121
+P+H C P +A L+ E +P + + C+ Y+ +W++
Sbjct: 25 TPDHRCRSPGVAELSLRCGWSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVD 84
Query: 122 -LIAGQIPNSTWPTKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSII 180
L + S P C GW + E P +I +E + +C Q+ VG I
Sbjct: 85 PLASLDTNRSRLPLGPCRDGWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFI 141
Query: 181 GGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAY 240
G IG++ADR+GR + + LI G+L + +T I+R I G+ ++ Y
Sbjct: 142 GSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGY 201
Query: 241 LILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXC 300
+++ E+V +Y+ V + + + YT + + ++ A HW+ + S
Sbjct: 202 ILITEFVGRRYRRTV-GIFYQVAYTVGLLVLAGVAYALPHWRWLQFTVSLPNFFFLLYYW 260
Query: 301 CIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKET-KEESHSCLEI 359
CIPESPRWL+S + EA+ I I++ N + + +ET K+ + S L++
Sbjct: 261 CIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQ---RLRLEEETGKKLNPSFLDL 317
Query: 360 FKRPPIRR-TFILM 372
+ P IR+ T ILM
Sbjct: 318 VRTPQIRKHTMILM 331
>BC034394-1|AAH34394.1| 322|Homo sapiens hypothetical protein
MGC34821 protein.
Length = 322
Score = 107 bits (256), Expect = 1e-22
Identities = 76/273 (27%), Positives = 128/273 (46%), Gaps = 21/273 (7%)
Query: 31 INFDELLIAAGEFGIYQILL--FFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELAN- 87
+ FD LL G G +QI L FF + LF V + T +P+H CWVP L N
Sbjct: 1 MGFDVLLDQVGGMGRFQICLIAFFCITNILLFPNIVLEN---FTAFTPSHRCWVPLLDND 57
Query: 88 -LTDTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKA 136
++D + TL+ IP+D + + CQ + W + + G PN+ P T+
Sbjct: 58 SVSDNDTGTLSKDDLLRISIPLDSNLR--PQKCQRFIHPQWQLLHLNGTFPNTNEPDTEP 115
Query: 137 CEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLP 196
C GW ++++ TI +E D +C+ S ++ Q+LF GS++GG + G ++DR GR
Sbjct: 116 CVDGWVYDRSSF-LSTIVTEWDLVCESQSLKSMVQSLFMAGSLLGGLIYGHLSDRVGRKI 174
Query: 197 AAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVA 256
L + FA F + I RF+AG + + +++ LE+ P+ ++M
Sbjct: 175 ICKLCFLQLAISNTCAAFAPTFLVYCILRFLAGFSTMTILGNTFILSLEWTLPRSRSMTI 234
Query: 257 NMAFALFYTSFTIAMPWISLACGHWKTISIVTS 289
M Y+ + + ++ A W + + S
Sbjct: 235 -MVLLCSYSVGQMLLGGLAFAIQDWHILQLTVS 266
>AB209484-1|BAD92721.1| 440|Homo sapiens solute carrier family 22
member 5 variant protein.
Length = 440
Score = 106 bits (254), Expect = 2e-22
Identities = 72/338 (21%), Positives = 138/338 (40%), Gaps = 2/338 (0%)
Query: 211 LTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIA 270
L F++NF F + + GM + + A+++ E + + + + + +FY +
Sbjct: 69 LQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMV 128
Query: 271 MPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINX 330
+P + W+ + + + IPESPRWL+S GR EEA I ++ N
Sbjct: 129 LPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANG 188
Query: 331 XXXXXXXXXRFKCTVSKETKEESHSCLEIFKRPPIRRTFILMCLEFTCCTIIFDALVRST 390
+ K++SH+ L++ + IR I+ + + ++ + L T
Sbjct: 189 IVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDT 248
Query: 391 GQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVP 450
L E+P+ + ++ ++ R++ + L L V +
Sbjct: 249 PNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLY 308
Query: 451 --SVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQI 508
+ + ++ +F V +++ +TAE+ PT VR G V +G+ LSPY VYL
Sbjct: 309 YLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGA 368
Query: 509 YISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNE 546
Y +LP LPE+ +P T ++
Sbjct: 369 YDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQ 406
>BC047565-1|AAH47565.1| 577|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 577
Score = 105 bits (252), Expect = 4e-22
Identities = 95/408 (23%), Positives = 165/408 (40%), Gaps = 13/408 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 139 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 198
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 199 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 257
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 316
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT +
Sbjct: 317 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSF 376
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
+ S LG E+P+ V MD +GR+ V + + CS V V
Sbjct: 377 SLNSVN-LGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV-LAYSLFCSALACGVVMV 434
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 435 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 494
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
V L ++P LPET K + T+ EA +L
Sbjct: 495 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKL 542
>AL050350-4|CAI42512.1| 577|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 577
Score = 105 bits (252), Expect = 4e-22
Identities = 95/408 (23%), Positives = 165/408 (40%), Gaps = 13/408 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 139 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 198
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 199 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 257
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 316
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT +
Sbjct: 317 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSF 376
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
+ S LG E+P+ V MD +GR+ V + + CS V V
Sbjct: 377 SLNSVN-LGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV-LAYSLFCSALACGVVMV 434
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 435 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 494
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
V L ++P LPET K + T+ EA +L
Sbjct: 495 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKL 542
>AB055798-1|BAC23062.1| 543|Homo sapiens carnitine transporter 2
protein.
Length = 543
Score = 105 bits (252), Expect = 4e-22
Identities = 95/408 (23%), Positives = 165/408 (40%), Gaps = 13/408 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 105 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 164
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 165 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 223
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 224 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 282
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT +
Sbjct: 283 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSF 342
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
+ S LG E+P+ V MD +GR+ V + + CS V V
Sbjct: 343 SLNSVN-LGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV-LAYSLFCSALACGVVMV 400
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 401 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 460
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
V L ++P LPET K + T+ EA +L
Sbjct: 461 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKL 508
>AF268892-1|AAK58593.1| 577|Homo sapiens organic cation transporter
OKB1 protein.
Length = 577
Score = 103 bits (246), Expect = 2e-21
Identities = 94/408 (23%), Positives = 164/408 (40%), Gaps = 13/408 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 139 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 198
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 199 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 257
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 316
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT +
Sbjct: 317 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSF 376
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
+ S LG E+P+ V D +GR+ V + + CS V V
Sbjct: 377 SLNSVN-LGGNEYLNLFLLGVVEIPAYTFVCIATDKVGRRTV-LAYSLFCSALACGVVMV 434
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 435 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 494
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
V L ++P LPET K + T+ EA +L
Sbjct: 495 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKL 542
>AY145502-1|AAN52928.1| 577|Homo sapiens putative transmembrane
transporter FLIPT 2 protein.
Length = 577
Score = 101 bits (242), Expect = 7e-21
Identities = 94/408 (23%), Positives = 163/408 (39%), Gaps = 13/408 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 139 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 198
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+
Sbjct: 199 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLG 257
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 258 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 316
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT +
Sbjct: 317 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSF 376
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
+ S LG E+P+ V D +GR+ V + + CS V V
Sbjct: 377 SLNSVN-LGGNEYLNLFLLGVVEIPAYTFVCIATDKVGRRTV-LAYSLFCSALACGVVMV 434
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 435 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 494
Query: 503 IVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAEEL 550
V L ++P LPET K + T+ EA +L
Sbjct: 495 SVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKL 542
>AF097491-1|AAD19357.1| 568|Homo sapiens organic anion transporter
3 protein.
Length = 568
Score = 98.7 bits (235), Expect = 5e-20
Identities = 80/383 (20%), Positives = 159/383 (41%), Gaps = 12/383 (3%)
Query: 127 IPNSTWPT-KACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLI 185
+PN T + C GW +N T+ +I +E D +C+ + AQ++F G +IGG ++
Sbjct: 84 LPNDTQRAMEPCLDGWVYNSTK---DSIVTEWDLVCNSNKLKEMAQSIFMAGILIGGLVL 140
Query: 186 GWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLE 245
G ++DR+GR S L+ G F+ F + ++RF+ G + ++ +E
Sbjct: 141 GDLSDRFGR-TILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGITLSTVILNVE 199
Query: 246 YVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPES 305
+V + + +++ A YT +P ++ A W+ + + S PES
Sbjct: 200 WVPTRMRAIMST-ALGYCYTFGQFILPGLAYAIPQWRWLQLTVSIPFFVFFLSSWWTPES 258
Query: 306 PRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETK--EESHSCLEIFKRP 363
RW + +E + K + KE + ++ ++F+ P
Sbjct: 259 IRWWSCLEVLEGPEDTPAGGCLQWQEEGERLSLEELKLNLQKEISLAKAKYTASDLFRIP 318
Query: 364 PIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMG 423
+L+ L + + +L + G ++P+ + + ++G
Sbjct: 319 IGAPHDLLLSLAWFATGFAYYSLAMGVEEFGVNLYILQIIFGGVDVPAKFITILSLSYLG 378
Query: 424 RKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARF---FVNISYNATMQWTAEVLPTQ 480
R C L FV + +V TVLA F ++ S++ +T+E+ PT
Sbjct: 379 RHTTQGRCPAPGRGAILALTFVPLDLQTVE-TVLAVFGKGCLSSSFSCLFLYTSELYPTV 437
Query: 481 VRGSGASVVHICGYIGTALSPYI 503
+R +G V ++ +G+ +SP +
Sbjct: 438 IRQTGMGVSNLWTRVGSMVSPLV 460
>BC101315-1|AAI01316.1| 398|Homo sapiens LOC387601 protein protein.
Length = 398
Score = 97.5 bits (232), Expect = 1e-19
Identities = 85/351 (24%), Positives = 151/351 (43%), Gaps = 25/351 (7%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS--PNHWCWVPELANLT- 89
F +LL G G +QIL +F V VY+ + +H CWV L N T
Sbjct: 1 FQDLLDQVGGLGRFQILQMVF---LIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTI 57
Query: 90 -DTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKACE 138
D + TL+ IP D + + C+ + W + + G PN++ P T+ C
Sbjct: 58 PDNDPGTLSQDALLRISIPFDSNLR--PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCV 115
Query: 139 HGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAA 198
GW ++++ P TI ++ D +C+ + A+ LF G ++GG L G ++DR+GR
Sbjct: 116 DGWVYDQSSFP-STIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRFGRKFVL 174
Query: 199 VYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANM 258
+S L + G FA + RF+AG A + ++ L+++E++T ++ M +
Sbjct: 175 RWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQFCAMALTL 234
Query: 259 AFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
I + ++ + +V S + ES RWL+ + EE
Sbjct: 235 TLCAASIGH-ITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLIINNKPEEG 293
Query: 319 INKILTISRINXXXXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPI 365
+ ++ + N K T+ +E + ++ HS E+ + P I
Sbjct: 294 LKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNI 344
>AB050269-1|BAB68364.1| 552|Homo sapiens organic anion transpoter 4
like protein protein.
Length = 552
Score = 97.5 bits (232), Expect = 1e-19
Identities = 107/536 (19%), Positives = 198/536 (36%), Gaps = 28/536 (5%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPI----DDSTKFGYSHCQVYDANWDEVLIAGQIPNSTWPTKACEHG 140
+ LAI I + S + ++W + + P PT++
Sbjct: 62 SILGSLSPEALLAISIPPGPNQSPISAAASASHSGSSWTPM---PRPPAGARPTRS--RV 116
Query: 141 WEFNK-TEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
W T P + +++ +CD + + AQ+++ G ++G G +DR+GR
Sbjct: 117 WMAGSMTAASSPPQSWQVELVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLT 176
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMA 259
+S L + G FA F + ++RF+ A MM +L+E+ + + +V +
Sbjct: 177 WSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLN 236
Query: 260 FALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAI 319
F + ++ W + +V S + ES RWLL+ GR++ +
Sbjct: 237 SLGFSFGHGLTAA-VAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGL 295
Query: 320 NKILTISRINXXXXXXXXXXRFKCTVSKETKEES-----HSCLEIFKRPPIRRTFILMCL 374
++ ++ IN + +S +E S S + + P +R + L
Sbjct: 296 QELWRVAAINGKGAVQDTLTP-EVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTL 354
Query: 375 EFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMML 434
+ F L LG ++P+ ++ +GR+ ++L
Sbjct: 355 CWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLL 414
Query: 435 CSVFTLLTVFV--GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHIC 492
+ L V G VL V ++ +++E+ PT +R + + +
Sbjct: 415 AGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMA 474
Query: 493 GYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPETTKKDIPQTFNEAE 548
G L P + L ++ WLP LPET +P T + +
Sbjct: 475 ARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQ 530
>AL050350-6|CAI42514.1| 432|Homo sapiens solute carrier family 22
(organic cation transporter), member 16 protein.
Length = 432
Score = 94.7 bits (225), Expect = 8e-19
Identities = 86/372 (23%), Positives = 156/372 (41%), Gaps = 13/372 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 56 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 115
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 116 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 174
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 175 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 233
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT ++ F +
Sbjct: 234 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFT-GSLGFYS 292
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
++ LG E+P+ V MD +GR+ V + + CS V V
Sbjct: 293 FSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV-LAYSLFCSALACGVVMV 351
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPY 502
+ V+ ++ +F + ++ +TAE+ PT VR + + + L+P+
Sbjct: 352 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPF 411
Query: 503 IVYLQIYISWLP 514
V L ++P
Sbjct: 412 SVDLSSIWIFIP 423
>AC002464-1|AAB67044.1| 456|Homo sapiens WUGSC:RG331P03.1 protein.
Length = 456
Score = 89.0 bits (211), Expect = 4e-17
Identities = 80/339 (23%), Positives = 143/339 (42%), Gaps = 13/339 (3%)
Query: 152 TITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGIL 211
T ++ + +CDR Q LF G ++G G+ +DR GR ++ L GI
Sbjct: 122 TAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIA 181
Query: 212 TTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAM 271
FA ++ F RF M +++ ++ ++E++ K +T A++ F+ T+ +
Sbjct: 182 AAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLV 240
Query: 272 PWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SR 327
W ++ S +PE+P WLLS GR EEA KI+ I +R
Sbjct: 241 ALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNR 299
Query: 328 INXXXXXXXXXXRFKCTVSKE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDA 385
+ + VS T+ + H+ +F I +RT + + FT ++ F +
Sbjct: 300 ASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFT-GSLGFYS 358
Query: 386 LVRSTGQLGXXXXXXXXXXXXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV 445
++ LG E+P+ V MD +GR+ V + + CS V V
Sbjct: 359 FSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTV-LAYSLFCSALACGVVMV 417
Query: 446 ---GSGVPSVMCTVLARFFVNISYNATMQWTAEVLPTQV 481
+ V+ ++ +F + ++ +TAE+ PT V
Sbjct: 418 IPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIV 456
>AK057306-1|BAB71419.1| 361|Homo sapiens protein ( Homo sapiens
cDNA FLJ32744 fis, clone TESTI2001420, weakly similar to
D.melanogaster mRNA for putative organic cation
transporter. ).
Length = 361
Score = 85.0 bits (201), Expect = 6e-16
Identities = 81/353 (22%), Positives = 147/353 (41%), Gaps = 13/353 (3%)
Query: 171 QALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGM 230
Q LF G ++G G+ +DR GR ++ L GI FA ++ F RF M
Sbjct: 4 QPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAM 63
Query: 231 AYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+++ ++ ++E++ K +T A++ F+ T+ + W ++ S
Sbjct: 64 VASGYLVVGFVYVMEFIGMKSRTW-ASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILST 122
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTI----SRINXXXXXXXXXXRFKCTVS 346
+PE+P WLLS GR EEA KI+ I +R + + VS
Sbjct: 123 VTVPFILCCWVLPETPFWLLSEGRYEEA-QKIVDIMAKWNRASSCKLSELLSLDLQGPVS 181
Query: 347 KE-TKEESHSCLEIFKRPPI-RRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXX 404
T+ + H+ +F I +RT + + FT ++ F + ++ LG
Sbjct: 182 NSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFT-GSLGFYSFSLNSVNLGGNEYLNLFLL 240
Query: 405 XXTELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFV---GSGVPSVMCTVLARFF 461
E+P+ V D +GR+ V + + CS V V + V+ ++ +F
Sbjct: 241 GVVEIPAYTFVCIATDKVGRRTV-LAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFA 299
Query: 462 VNISYNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLP 514
+ ++ +TAE+ PT VR + + + L+P+ V L ++P
Sbjct: 300 IGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIP 352
>AK131327-1|BAD18487.1| 349|Homo sapiens protein ( Homo sapiens
cDNA FLJ16331 fis, clone SYNOV2013637, moderately
similar to Homo sapiens putative renal organic anion
transporter 1 ).
Length = 349
Score = 73.3 bits (172), Expect = 2e-12
Identities = 36/125 (28%), Positives = 67/125 (53%), Gaps = 4/125 (3%)
Query: 128 PNSTWP---TKACEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFL 184
PNS+ P T+ C+ GW +N++ P TI E D +C+ + + AQ+++ G ++G +
Sbjct: 97 PNSSIPGAATEGCKDGWVYNRSVFP-STIVMEWDLVCEARTLRDLAQSVYMAGVLVGAAV 155
Query: 185 IGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILL 244
G +ADR G V+S L G T + +F+ + ++RF+ GM + ++ + ++
Sbjct: 156 FGSLADRLGCKGPLVWSYLQLAASGAATAYFSSFSAYCVFRFLMGMTFSGIILNSVSLVA 215
Query: 245 EYVTP 249
V P
Sbjct: 216 SRVIP 220
>BC026291-1|AAH26291.1| 440|Homo sapiens Unknown (protein for
IMAGE:4608353) protein.
Length = 440
Score = 69.3 bits (162), Expect = 3e-11
Identities = 72/334 (21%), Positives = 131/334 (39%), Gaps = 42/334 (12%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
+ LAI I C+ + W L+ ++W T+ C G
Sbjct: 62 SILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W ++++ I TI ++ + +CD + + AQ+++ G ++G G +DR+GR +
Sbjct: 120 WVYDRS-IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTW 178
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMM----------------------- 237
S L + G FA F + ++RF+ A MM
Sbjct: 179 SYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLHAGSRA 238
Query: 238 --MAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXX 295
+ L ++E+ + + +V + F + ++ W + +V S
Sbjct: 239 EPLGLLAVMEWTAARARPLVMTLNSLGFSFGHGLTAA-VAYGVRDWTLLQLVVSVPFFLC 297
Query: 296 XXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
+ ES RWLL+ GR++ + ++ ++ IN
Sbjct: 298 FLYSWWLAESARWLLTTGRLDWGLQELWRVAAIN 331
>BC030978-1|AAH30978.1| 242|Homo sapiens SLC22A2 protein protein.
Length = 242
Score = 68.9 bits (161), Expect = 5e-11
Identities = 54/223 (24%), Positives = 95/223 (42%), Gaps = 18/223 (8%)
Query: 34 DELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLT---- 89
D++L GEF +Q +FF + +Y +F+ +P+H C P +A L+
Sbjct: 6 DDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGF-TPDHRCRSPGVAELSLRCG 64
Query: 90 --DTERRTLAIP-IDDSTKFGYSHCQVYDANWDEV-------LIAGQIPNSTWPTKACEH 139
E +P + + C+ Y+ +W++ L + S P C
Sbjct: 65 WSPAEELNYTVPGPGPAGEASPRQCRRYEVDWNQSTFDCVDPLASLDTNRSRLPLGPCRD 124
Query: 140 GWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAV 199
GW + E P +I +E + +C Q+ VG IG IG++ADR+GR +
Sbjct: 125 GWVY---ETPGSSIVTEFNLVCANSWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLL 181
Query: 200 YSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLI 242
+ LI G+L + +T I+R I G+ ++ Y++
Sbjct: 182 TTVLINAAAGVLMAISPTYTWMLIFRLIQGLVSKAGWLIGYIL 224
>BC101314-1|AAI01315.1| 201|Homo sapiens LOC387601 protein protein.
Length = 201
Score = 63.7 bits (148), Expect = 2e-09
Identities = 50/173 (28%), Positives = 81/173 (46%), Gaps = 20/173 (11%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS--PNHWCWVPELANLT- 89
F +LL G G +QIL +F V VY+ + +H CWV L N T
Sbjct: 2 FQDLLDQVGGLGRFQILQMVF---LIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTI 58
Query: 90 -DTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKACE 138
D + TL+ IP D + + C+ + W + + G PN++ P T+ C
Sbjct: 59 PDNDPGTLSQDALLRISIPFDSNLR--PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCV 116
Query: 139 HGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADR 191
GW ++++ P TI ++ D +C+ + A+ LF G ++GG L G ++DR
Sbjct: 117 DGWVYDQSSFP-STIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDR 168
>BC022379-1|AAH22379.1| 238|Homo sapiens SLC22A9 protein protein.
Length = 238
Score = 61.7 bits (143), Expect = 7e-09
Identities = 51/187 (27%), Positives = 83/187 (44%), Gaps = 18/187 (9%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTDTE 92
F +LL AG+ +QIL S F ++++ T P H CWV L N T ++
Sbjct: 3 FQDLLGHAGDLWRFQILQTVFLS-IFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSD 61
Query: 93 RRT----------LAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPN-STWPTKACEHG 140
T ++IP+D + + C+ + W + + G PN S + C G
Sbjct: 62 NDTGALSQDALLRISIPLDSNMR--PEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVAD--RYGRLPAA 198
W +++ TI +E D +CD S + A+ +F G ++GG L G ++D R G
Sbjct: 120 WVYDRISFS-STIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDSSRVGNTQIP 178
Query: 199 VYSTLIG 205
+ IG
Sbjct: 179 GHGNYIG 185
>BC040876-1|AAH40876.1| 341|Homo sapiens C6orf85 protein protein.
Length = 341
Score = 60.5 bits (140), Expect = 2e-08
Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W++ + S+ D +CD A+ VG I G + G +AD GR P ++
Sbjct: 183 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 242
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S + + G+ + N T FS RF G ++ Y + +E P + M+ M
Sbjct: 243 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI-TMVA 301
Query: 261 ALFYTSFTIAMPWISLACGHWKTI 284
+ + MP ++ C W+ +
Sbjct: 302 SFVAMAGQFLMPGLAALCRDWQVL 325
>AL445309-6|CAI40959.1| 213|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 213
Score = 60.5 bits (140), Expect = 2e-08
Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W++ + S+ D +CD A+ VG I G + G +AD GR P ++
Sbjct: 55 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 114
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S + + G+ + N T FS RF G ++ Y + +E P + M+ M
Sbjct: 115 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI-TMVA 173
Query: 261 ALFYTSFTIAMPWISLACGHWKTI 284
+ + MP ++ C W+ +
Sbjct: 174 SFVAMAGQFLMPGLAALCRDWQVL 197
>AL160398-1|CAI12303.1| 213|Homo sapiens chromosome 6 open reading
frame 85 protein.
Length = 213
Score = 60.5 bits (140), Expect = 2e-08
Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 1/144 (0%)
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W++ + S+ D +CD A+ VG I G + G +AD GR P ++
Sbjct: 55 WDYGIRAGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLF 114
Query: 201 STLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAF 260
S + + G+ + N T FS RF G ++ Y + +E P + M+ M
Sbjct: 115 SIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMI-TMVA 173
Query: 261 ALFYTSFTIAMPWISLACGHWKTI 284
+ + MP ++ C W+ +
Sbjct: 174 SFVAMAGQFLMPGLAALCRDWQVL 197
>AB075876-1|BAD38658.1| 269|Homo sapiens putative protein product
of HMFN2567 protein.
Length = 269
Score = 57.2 bits (132), Expect = 1e-07
Identities = 44/203 (21%), Positives = 87/203 (42%), Gaps = 6/203 (2%)
Query: 179 IIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMM 238
++GG + G V+DR+GR + L + FA F + + RF+AG + +
Sbjct: 2 LVGGIIGGHVSDRFGRRFILRWCLLQLAITDTCAAFAPTFPVYCVLRFLAGFSSMIIISN 61
Query: 239 AYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXX 298
L + E++ P K +V ++ I + ++ W+T+ +V S
Sbjct: 62 NSLPITEWIRPNSKALVVILSSGALSIG-QIILGGLAYVFRDWQTLHVVASVPFFVFFLL 120
Query: 299 XCCIPESPRWLLSMGRVEEAINKILTISRIN--XXXXXXXXXXRFKCTVSKE--TKEESH 354
+ ES RWL+ +++E + + ++R N + T+ +E +
Sbjct: 121 SRWLVESARWLIITNKLDEGLKALRKVARTNGIKNAEETLNIEVVRSTMQEELDAAQTKT 180
Query: 355 SCLEIFKRPPIR-RTFILMCLEF 376
+ ++F+ P +R R IL+ L F
Sbjct: 181 TVCDLFRNPSMRKRICILVFLRF 203
>AY358258-1|AAQ88625.1| 245|Homo sapiens trans-like protein
protein.
Length = 245
Score = 56.4 bits (130), Expect = 3e-07
Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTS 289
+ W+T++I+ +
Sbjct: 213 QYALLGYFIRSWRTLAILVN 232
>AL365318-1|CAH70685.1| 245|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 245
Score = 56.4 bits (130), Expect = 3e-07
Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTS 289
+ W+T++I+ +
Sbjct: 213 QYALLGYFIRSWRTLAILVN 232
>AL357137-1|CAH70379.1| 245|Homo sapiens solute carrier family 22
(organic cation transporter), member 15 protein.
Length = 245
Score = 56.4 bits (130), Expect = 3e-07
Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Query: 150 YPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGG 209
+ +I SE I +R + A + FF G +G G ++DR+GR + + L
Sbjct: 94 FTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFA 153
Query: 210 ILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTI 269
I F+ ++ F++ RF+ GM ++A+++L E V Y + ++ LF+
Sbjct: 154 IANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIA 212
Query: 270 AMPWISLACGHWKTISIVTS 289
+ W+T++I+ +
Sbjct: 213 QYALLGYFIRSWRTLAILVN 232
>AK128610-1|BAC87527.1| 221|Homo sapiens . protein.
Length = 221
Score = 55.2 bits (127), Expect = 6e-07
Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 2/141 (1%)
Query: 408 ELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVP--SVMCTVLARFFVNIS 465
E+P+ + ++ ++ R++ + L L V + + + ++ +F V +
Sbjct: 47 EVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAA 106
Query: 466 YNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXX 525
++ +TAE+ PT VR G V +G+ LSPY VYL Y +LP
Sbjct: 107 FSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILT 166
Query: 526 XXXXXXLPETTKKDIPQTFNE 546
LPE+ +P T ++
Sbjct: 167 AILTLFLPESFGTPLPDTIDQ 187
>BC020565-1|AAH20565.1| 538|Homo sapiens solute carrier family 22
(organic cation transporter), member 17 protein.
Length = 538
Score = 54.4 bits (125), Expect = 1e-06
Identities = 47/197 (23%), Positives = 77/197 (39%), Gaps = 7/197 (3%)
Query: 137 CEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLP 196
C W++N + + D +CD G Q LF +G G +G+ ADR+GR
Sbjct: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR-- 127
Query: 197 AAVYSTLIGCLG--GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTM 254
+ +G +G G+ A + T RF+ G + YL+ LE P +
Sbjct: 128 RGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLR 187
Query: 255 VANMAFALFYTSFTIAMPWISLACGHWKTIS--IVTSXXXXXXXXXXCCIPESPRWLLSM 312
VA +A L ++L W+ + I ES RWL+
Sbjct: 188 VA-LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVK 246
Query: 313 GRVEEAINKILTISRIN 329
++EEA + + ++ N
Sbjct: 247 RQIEEAQSVLRILAERN 263
Score = 35.1 bits (77), Expect = 0.69
Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 1/95 (1%)
Query: 474 AEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLP 533
AEV+PT VRG G ++ G +G P + ++L LP
Sbjct: 435 AEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILSIMLLP 494
Query: 534 ETTKKDIPQTFNEAEELSRNINLWEMPCLSRPKNV 568
ET +K +P+ + EL R +L P +R +V
Sbjct: 495 ETKRKLLPEVLRDG-ELCRRPSLLRQPPPTRCDHV 528
>AK127610-1|BAC87056.1| 248|Homo sapiens protein ( Homo sapiens
cDNA FLJ45708 fis, clone FEHRT2002708, weakly similar
to Mus musculus solute carrier family 22 (organic cation
transporter). ).
Length = 248
Score = 53.2 bits (122), Expect = 2e-06
Identities = 42/193 (21%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Query: 177 GSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCM 236
G ++GG L G ++DR+GR +S L + G FA + RF+AG A + +
Sbjct: 3 GMMVGGNLYGHLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSII 62
Query: 237 MMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXX 296
+ L+++E++T ++ M + I + ++ + +V S
Sbjct: 63 VNTVLLIVEWITHQFCAMALTLTLCAASIGH-ITLGSLAFVIRDQCILQLVMSAPCFVFF 121
Query: 297 XXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXR--FKCTVSKETK--EE 352
+ ES RWL+ + EE + ++ + N K T+ +E + ++
Sbjct: 122 LFSRWLAESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQK 181
Query: 353 SHSCLEIFKRPPI 365
HS E+ + P I
Sbjct: 182 KHSLCELLRIPNI 194
>BC090870-1|AAH90870.1| 449|Homo sapiens SLC22A17 protein protein.
Length = 449
Score = 52.8 bits (121), Expect = 3e-06
Identities = 46/193 (23%), Positives = 76/193 (39%), Gaps = 7/193 (3%)
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVY 200
W++N + + D +CD G Q LF +G G +G+ ADR+GR +
Sbjct: 3 WDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR--RGIV 60
Query: 201 STLIGCLG--GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANM 258
+G +G G+ A + T RF+ G + YL+ LE P + VA +
Sbjct: 61 LLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVA-L 119
Query: 259 AFALFYTSFTIAMPWISLACGHWKTIS--IVTSXXXXXXXXXXCCIPESPRWLLSMGRVE 316
A L ++L W+ + I ES RWL+ ++E
Sbjct: 120 AGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIE 179
Query: 317 EAINKILTISRIN 329
EA + + ++ N
Sbjct: 180 EAQSVLRILAERN 192
Score = 37.9 bits (84), Expect = 0.097
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 5/160 (3%)
Query: 413 CV-VAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCT---VLARFFVNISYNA 468
CV + +D GR+ + + M L + +L+ + + + T VL F +
Sbjct: 281 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAIL 340
Query: 469 TMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXX 528
+ AEV+PT VRG G ++ G +G P + ++L
Sbjct: 341 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 400
Query: 529 XXXLPETTKKDIPQTFNEAEELSRNINLWEMPCLSRPKNV 568
LPET +K +P+ + EL R +L P +R +V
Sbjct: 401 IMLLPETKRKLLPEVLRDG-ELCRRPSLLRQPPPTRCDHV 439
>BC094722-1|AAH94722.1| 548|Homo sapiens SV2 related protein
homolog (rat) protein.
Length = 548
Score = 50.0 bits (114), Expect = 2e-05
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 2/103 (1%)
Query: 407 TELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLT-VFVGSGVPSVMCTVLARFFVNIS 465
+E P + V +I+D +GRK C ++ S +LL + VG V +++ + AR F++
Sbjct: 382 SEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFI-ARAFISGG 440
Query: 466 YNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQI 508
+ A +T EV PT R G +G ++P+I + +
Sbjct: 441 FQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVML 483
>BC033587-1|AAH33587.1| 548|Homo sapiens SV2 related protein
homolog (rat) protein.
Length = 548
Score = 50.0 bits (114), Expect = 2e-05
Identities = 29/103 (28%), Positives = 52/103 (50%), Gaps = 2/103 (1%)
Query: 407 TELPSMCVVAFIMDWMGRKWVTIGCMMLCSVFTLLT-VFVGSGVPSVMCTVLARFFVNIS 465
+E P + V +I+D +GRK C ++ S +LL + VG V +++ + AR F++
Sbjct: 382 SEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFI-ARAFISGG 440
Query: 466 YNATMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQI 508
+ A +T EV PT R G +G ++P+I + +
Sbjct: 441 FQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVML 483
>AL583834-7|CAI14466.1| 211|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 211
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/184 (21%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 355 SCLEIFKRPPIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCV 414
S L++F+ P +R + + + + L LG ELPS +
Sbjct: 26 SYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLL 85
Query: 415 VAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPS--VMCTVLARFFVNISYNATMQW 472
V + + GR+ G ++ ++ + V S + S + V+ + F ++ +
Sbjct: 86 VYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLF 145
Query: 473 TAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQ-IYISWLPXXXXXXXXXXXXXXXXX 531
T+E+ PT +R +G + + G +G +L+P L +++S LP
Sbjct: 146 TSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLS-LPKLTYGGIALLAAGTALL 204
Query: 532 LPET 535
LPET
Sbjct: 205 LPET 208
>CR457086-1|CAG33367.1| 683|Homo sapiens SV2B protein.
Length = 683
Score = 49.2 bits (112), Expect = 4e-05
Identities = 39/180 (21%), Positives = 77/180 (42%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G + G F++G +AD+ GR S + L++
Sbjct: 135 SAEKD-MCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSS 193
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTS--FTIAM 271
F + + F R I+G+ + + + E+++ + + + + T + AM
Sbjct: 194 FVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAM 253
Query: 272 PW---------ISLACGH----WKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S+ + W+ IV + +PESPR+LL MG+ +EA
Sbjct: 254 AWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEA 313
>BC030011-1|AAH30011.1| 683|Homo sapiens SV2B protein protein.
Length = 683
Score = 49.2 bits (112), Expect = 4e-05
Identities = 39/180 (21%), Positives = 77/180 (42%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G + G F++G +AD+ GR S + L++
Sbjct: 135 SAEKD-MCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSS 193
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTS--FTIAM 271
F + + F R I+G+ + + + E+++ + + + + T + AM
Sbjct: 194 FVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAM 253
Query: 272 PW---------ISLACGH----WKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S+ + W+ IV + +PESPR+LL MG+ +EA
Sbjct: 254 AWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEA 313
>AY358183-1|AAQ88550.1| 445|Homo sapiens SLC22A12 protein.
Length = 445
Score = 49.2 bits (112), Expect = 4e-05
Identities = 48/254 (18%), Positives = 91/254 (35%), Gaps = 8/254 (3%)
Query: 302 IPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETKEESH-----SC 356
+ ES RWLL+ GR++ + ++ ++ IN + +S +E S S
Sbjct: 171 LAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTP-EVLLSAMREELSMGQPPASL 229
Query: 357 LEIFKRPPIRRTFILMCLEFTCCTIIFDALVRSTGQLGXXXXXXXXXXXXTELPSMCVVA 416
+ + P +R + L + F L LG ++P+
Sbjct: 230 GTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGAL 289
Query: 417 FIMDWMGRKWVTIGCMMLCSVFTLLTVFVGS--GVPSVMCTVLARFFVNISYNATMQWTA 474
++ +GR+ ++L + L V G VL V ++ +++
Sbjct: 290 LLLSHLGRRPTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTYITIYSS 349
Query: 475 EVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXXXXXLPE 534
E+ PT +R + + + G L P + L ++ WLP LPE
Sbjct: 350 ELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPE 409
Query: 535 TTKKDIPQTFNEAE 548
T +P T + +
Sbjct: 410 TQSLPLPDTIQDVQ 423
Score = 48.0 bits (109), Expect = 9e-05
Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 16/172 (9%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD-- 90
F ELL G G +Q+L A ++ + F + P+H CW P L N T
Sbjct: 3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENF-SAAVPSHRCWAPLLDNSTAQA 61
Query: 91 ------TERRTLAIPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP---TKACEHG 140
+ LAI I C+ + W L+ ++W T+ C G
Sbjct: 62 SILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQ--LLDPNATATSWSEADTEPCVDG 119
Query: 141 WEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRY 192
W ++++ I TI ++ + +CD + + AQ+++ G ++G G +DR+
Sbjct: 120 WVYDRS-IFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRW 170
>AB018278-1|BAA34455.2| 707|Homo sapiens KIAA0735 protein protein.
Length = 707
Score = 49.2 bits (112), Expect = 4e-05
Identities = 39/180 (21%), Positives = 77/180 (42%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G + G F++G +AD+ GR S + L++
Sbjct: 159 SAEKD-MCLSSSKKGMLGMIVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSS 217
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTS--FTIAM 271
F + + F R I+G+ + + + E+++ + + + + T + AM
Sbjct: 218 FVQGYGAFLFCRLISGIGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAM 277
Query: 272 PW---------ISLACGH----WKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S+ + W+ IV + +PESPR+LL MG+ +EA
Sbjct: 278 AWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEA 337
>Y17801-1|CAB89809.1| 477|Homo sapiens glucose transporter 8
protein.
Length = 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
A+ +G+ GG L GW+ DR GR + + ++ G + T A++ R + G+A
Sbjct: 74 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
Query: 232 YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXX 291
++A + + E P + ++ + + +A +++ W+ ++++
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA--YLAGWVLEWRWLAVLGCVP 191
Query: 292 XXXXXXXXCCIPESPRWLLSMGRVEEAI 319
C +PE+PR+LL+ R +EA+
Sbjct: 192 PSLMLLLMCFMPETPRFLLTQHRRQEAM 219
>BC019043-1|AAH19043.1| 477|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
A+ +G+ GG L GW+ DR GR + + ++ G + T A++ R + G+A
Sbjct: 74 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
Query: 232 YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXX 291
++A + + E P + ++ + + +A +++ W+ ++++
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA--YLAGWVLEWRWLAVLGCVP 191
Query: 292 XXXXXXXXCCIPESPRWLLSMGRVEEAI 319
C +PE+PR+LL+ R +EA+
Sbjct: 192 PSLMLLLMCFMPETPRFLLTQHRRQEAM 219
>AL583834-6|CAI14465.1| 147|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 147
Score = 47.6 bits (108), Expect = 1e-04
Identities = 28/137 (20%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 156 EMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA 215
E D +C++ A FF G ++G G+++DR+GR + + + + G+ + +
Sbjct: 2 EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAAS 61
Query: 216 RNFTEFSIYRFIAGMA---YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMP 272
++ F+I R + G A + +M LE++ +++T VA + + F+T + +
Sbjct: 62 VSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRT-VAGVLSSTFWTGGVMLLA 120
Query: 273 WISLACGHWKTISIVTS 289
+ W+ + + +
Sbjct: 121 LVGYLIRDWRWLLLAVT 137
>AL445222-5|CAH72918.1| 477|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
A+ +G+ GG L GW+ DR GR + + ++ G + T A++ R + G+A
Sbjct: 74 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
Query: 232 YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXX 291
++A + + E P + ++ + + +A +++ W+ ++++
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA--YLAGWVLEWRWLAVLGCVP 191
Query: 292 XXXXXXXXCCIPESPRWLLSMGRVEEAI 319
C +PE+PR+LL+ R +EA+
Sbjct: 192 PSLMLLLMCFMPETPRFLLTQHRRQEAM 219
>AL445222-4|CAH72917.1| 411|Homo sapiens solute carrier family 2,
(facilitated glucose transporter) member 8 protein.
Length = 411
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
A+ +G+ GG L GW+ DR GR + + ++ G + T A++ R + G+A
Sbjct: 74 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
Query: 232 YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXX 291
++A + + E P + ++ + + +A +++ W+ ++++
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA--YLAGWVLEWRWLAVLGCVP 191
Query: 292 XXXXXXXXCCIPESPRWLLSMGRVEEAI 319
C +PE+PR+LL+ R +EA+
Sbjct: 192 PSLMLLLMCFMPETPRFLLTQHRRQEAM 219
>AJ245937-1|CAB75702.1| 477|Homo sapiens glucose transporter
protein.
Length = 477
Score = 47.6 bits (108), Expect = 1e-04
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
A+ +G+ GG L GW+ DR GR + + ++ G + T A++ R + G+A
Sbjct: 74 AVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLA 133
Query: 232 YDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXX 291
++A + + E P + ++ + + +A +++ W+ ++++
Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA--YLAGWVLEWRWLAVLGCVP 191
Query: 292 XXXXXXXXCCIPESPRWLLSMGRVEEAI 319
C +PE+PR+LL+ R +EA+
Sbjct: 192 PSLMLLLMCFMPETPRFLLTQHRRQEAM 219
>AK075127-1|BAC11419.1| 248|Homo sapiens protein ( Homo sapiens
cDNA FLJ90646 fis, clone PLACE1004279. ).
Length = 248
Score = 45.6 bits (103), Expect = 5e-04
Identities = 27/128 (21%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Query: 242 ILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCC 301
+++E+ T + + + F ++ A+ ++ A W+T+ + S
Sbjct: 11 LMVEWTTTSRRAVTMTVVGCAF-SAGQAALGGLAFALRDWRTLQLAASVPFFAISLISWW 69
Query: 302 IPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKE---TKEESHSCLE 358
+PES RWL+ G+ ++A+ ++ ++RIN + KE + +E S L+
Sbjct: 70 LPESARWLIIKGKPDQALQELRKVARINGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLD 129
Query: 359 IFKRPPIR 366
+F P +R
Sbjct: 130 LFCVPVLR 137
>BC101317-1|AAI01318.1| 168|Homo sapiens LOC387601 protein protein.
Length = 168
Score = 45.2 bits (102), Expect = 6e-04
Identities = 40/149 (26%), Positives = 63/149 (42%), Gaps = 19/149 (12%)
Query: 33 FDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPS--PNHWCWVPELANLT- 89
F +LL G G +QIL +F V VY+ + +H CWV L N T
Sbjct: 3 FQDLLDQVGGLGRFQILQMVF---LIMFNVIVYHQTQLENFAAFILDHRCWVHILDNDTI 59
Query: 90 -DTERRTLA--------IPIDDSTKFGYSHCQVY-DANWDEVLIAGQIPNSTWP-TKACE 138
D + TL+ IP D + + C+ + W + + G PN++ P T+ C
Sbjct: 60 PDNDPGTLSQDALLRISIPFDSNLR--PEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCV 117
Query: 139 HGWEFNKTEIPYPTITSEMDWICDRGSYQ 167
GW ++++ P +T +C YQ
Sbjct: 118 DGWVYDQSSFPSTIVTKVAGRVCSVAHYQ 146
>BC060766-1|AAH60766.1| 497|Homo sapiens SLC2A14 protein protein.
Length = 497
Score = 45.2 bits (102), Expect = 6e-04
Identities = 45/207 (21%), Positives = 79/207 (38%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILT---TFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A + + R +
Sbjct: 69 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 128
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + L G W +
Sbjct: 129 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 188
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T C PESPR+LL + EE +IL R+ K
Sbjct: 189 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRIL--QRLWGTQDVSQDIQEMKDE 246
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 247 SARMSQEKQVTVLELFRVSSYRQPIII 273
>AY357941-1|AAQ63763.1| 497|Homo sapiens glucose transporter 14
short isoform protein.
Length = 497
Score = 45.2 bits (102), Expect = 6e-04
Identities = 45/207 (21%), Positives = 79/207 (38%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILT---TFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A + + R +
Sbjct: 69 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 128
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + L G W +
Sbjct: 129 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 188
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T C PESPR+LL + EE +IL R+ K
Sbjct: 189 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRIL--QRLWGTQDVSQDIQEMKDE 246
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 247 SARMSQEKQVTVLELFRVSSYRQPIII 273
>AF481879-1|AAL89710.1| 520|Homo sapiens glucose transporter 14
long form protein.
Length = 520
Score = 45.2 bits (102), Expect = 6e-04
Identities = 45/207 (21%), Positives = 79/207 (38%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILT---TFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A + + R +
Sbjct: 92 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 151
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + L G W +
Sbjct: 152 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 211
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T C PESPR+LL + EE +IL R+ K
Sbjct: 212 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRIL--QRLWGTQDVSQDIQEMKDE 269
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 270 SARMSQEKQVTVLELFRVSSYRQPIII 296
>AF481878-1|AAL89709.1| 497|Homo sapiens glucose transporter 14
short form protein.
Length = 497
Score = 45.2 bits (102), Expect = 6e-04
Identities = 45/207 (21%), Positives = 79/207 (38%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILT---TFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A + + R +
Sbjct: 69 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVI 128
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + L G W +
Sbjct: 129 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVL 188
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T C PESPR+LL + EE +IL R+ K
Sbjct: 189 LGFTILPAILQSAALPCCPESPRFLLINRKKEENATRIL--QRLWGTQDVSQDIQEMKDE 246
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 247 SARMSQEKQVTVLELFRVSSYRQPIII 273
>AL583834-2|CAI14461.1| 278|Homo sapiens solute carrier family 22
(organic anion transporter), member 7 protein.
Length = 278
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/76 (25%), Positives = 39/76 (51%)
Query: 156 EMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA 215
E D +C++ A FF G ++G G+++DR+GR + + + + G+ + +
Sbjct: 192 EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAAS 251
Query: 216 RNFTEFSIYRFIAGMA 231
++ F+I R + G A
Sbjct: 252 VSYVMFAITRTLTGSA 267
>BX537754-1|CAD97824.1| 742|Homo sapiens hypothetical protein
protein.
Length = 742
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 192 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 250
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 251 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 310
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 311 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 370
>BC045111-1|AAH45111.1| 742|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 742
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 192 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 250
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 251 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 310
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 311 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 370
>BC000776-1|AAH00776.2| 604|Homo sapiens SV2A protein protein.
Length = 604
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 54 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 112
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 113 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 172
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 173 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 232
>AL591493-21|CAI12573.1| 682|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 682
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 192 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 250
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 251 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 310
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 311 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 370
>AL591493-20|CAI12572.1| 742|Homo sapiens synaptic vesicle
glycoprotein 2A protein.
Length = 742
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 192 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 250
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 251 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 310
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 311 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 370
>AK075480-1|BAC11645.1| 682|Homo sapiens protein ( Homo sapiens
cDNA PSEC0174 fis, clone NT2RP2002760, highly similar to
SYNAPTIC VESICLE PROTEIN 2. ).
Length = 682
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 192 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 250
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 251 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 310
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 311 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 370
>AB018279-1|BAA34456.2| 748|Homo sapiens KIAA0736 protein protein.
Length = 748
Score = 43.2 bits (97), Expect = 0.003
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S + + ++G ++G FL G +ADR GR + S + + ++
Sbjct: 198 SAEKD-MCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSS 256
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G+ + + + E++ + + + F + + AM
Sbjct: 257 FVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAM 316
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S G W+ +V + PESPR+ L G+ +EA
Sbjct: 317 AWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEA 376
>DQ658848-1|ABG45942.1| 207|Homo sapiens esophageal carcinoma NGAL
receptor transcript variant 3 protein.
Length = 207
Score = 41.1 bits (92), Expect = 0.010
Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 4/108 (3%)
Query: 137 CEHGWEFNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLP 196
C W++N + + D +CD G Q LF +G G +G+ AD +GR
Sbjct: 70 CLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILGQILFILGFASGYLFLGYPADGFGR-- 127
Query: 197 AAVYSTLIGCLG--GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLI 242
+ +G +G G+ A + T RF+ G + YL+
Sbjct: 128 RGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLM 175
>BC100827-1|AAI00828.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 41.1 bits (92), Expect = 0.010
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S ++ ++G ++G F G +AD+ GR + + + L++
Sbjct: 178 SAETD-LCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSS 236
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G + + E + + + + F + + AM
Sbjct: 237 FVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAM 296
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S + G W+ IV + +PESPR+LL +G+ +EA
Sbjct: 297 AWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEA 356
Score = 32.3 bits (70), Expect = 4.8
Identities = 22/79 (27%), Positives = 36/79 (45%)
Query: 418 IMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVL 477
+ D +GRK + CM + F L+ FV + C +L+ F + + + AEVL
Sbjct: 211 LADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 478 PTQVRGSGASVVHICGYIG 496
+ RG S + + IG
Sbjct: 271 AREKRGEHLSWLCMFWMIG 289
>BC100826-1|AAI00827.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 41.1 bits (92), Expect = 0.010
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S ++ ++G ++G F G +AD+ GR + + + L++
Sbjct: 178 SAETD-LCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSS 236
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G + + E + + + + F + + AM
Sbjct: 237 FVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAM 296
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S + G W+ IV + +PESPR+LL +G+ +EA
Sbjct: 297 AWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEA 356
Score = 32.3 bits (70), Expect = 4.8
Identities = 22/79 (27%), Positives = 36/79 (45%)
Query: 418 IMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVL 477
+ D +GRK + CM + F L+ FV + C +L+ F + + + AEVL
Sbjct: 211 LADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 478 PTQVRGSGASVVHICGYIG 496
+ RG S + + IG
Sbjct: 271 AREKRGEHLSWLCMFWMIG 289
>BC100825-1|AAI00826.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 41.1 bits (92), Expect = 0.010
Identities = 37/180 (20%), Positives = 73/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S ++ ++G ++G F G +AD+ GR + + + L++
Sbjct: 178 SAETD-LCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSS 236
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G + + E + + + + F + + AM
Sbjct: 237 FVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAM 296
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S + G W+ IV + +PESPR+LL +G+ +EA
Sbjct: 297 AWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEA 356
Score = 32.3 bits (70), Expect = 4.8
Identities = 22/79 (27%), Positives = 36/79 (45%)
Query: 418 IMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVL 477
+ D +GRK + CM + F L+ FV + C +L+ F + + + AEVL
Sbjct: 211 LADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 478 PTQVRGSGASVVHICGYIG 496
+ RG S + + IG
Sbjct: 271 AREKRGEHLSWLCMFWMIG 289
>K03195-1|AAA52571.1| 492|Homo sapiens SGLT1 protein.
Length = 492
Score = 39.5 bits (88), Expect = 0.032
Identities = 45/208 (21%), Positives = 86/208 (41%), Gaps = 11/208 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA---RNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ + +L F+ ++F + RFI
Sbjct: 70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WK-T 283
G+ + + E ++ + + IA + + G+ W
Sbjct: 130 GVYCGLTTGFVPMYVGEVSPTAFRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 189
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKC 343
+SI+ C PESPR+LL + R EE K + + ++ K
Sbjct: 190 LSIIFIPALLQCIVLPFC-PESPRFLL-INRNEENRAKSV-LKKLRGTADVTHDLQEMKE 246
Query: 344 TVSKETKEESHSCLEIFKRPPIRRTFIL 371
+ +E+ + LE+F+ P R+ ++
Sbjct: 247 ESRQMMREKKVTILELFRSPAYRQPILI 274
>BC128580-1|AAI28581.1| 405|Homo sapiens C6orf85 protein protein.
Length = 405
Score = 39.5 bits (88), Expect = 0.032
Identities = 25/109 (22%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 221 FSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGH 280
FS RF G ++ Y + +E P + M+ +A + + MP ++ C
Sbjct: 2 FSTLRFFEGFCLAGIILTLYALRIELCPPGKRFMITMVA-SFVAMAGQFLMPGLAALCRD 60
Query: 281 WKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRIN 329
W+ + + PES RWL++ + E A IL ++ N
Sbjct: 61 WQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKRLILHFTQKN 109
>BC100824-1|AAI00825.1| 727|Homo sapiens synaptic vesicle
glycoprotein 2C protein.
Length = 727
Score = 39.5 bits (88), Expect = 0.032
Identities = 37/180 (20%), Positives = 72/180 (40%), Gaps = 16/180 (8%)
Query: 154 TSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTT 213
++E D +C S ++ ++G ++G F G +AD+ GR + + + L++
Sbjct: 178 SAETD-LCIPNSGSGWLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAFLSS 236
Query: 214 FARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVAN--MAFALFYTSFTIAM 271
F + + F R ++G + + E + + + + F + + AM
Sbjct: 237 FVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAM 296
Query: 272 PWI-------SLACG------HWKTISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEA 318
W S + G W+ IV + +PESPR LL +G+ +EA
Sbjct: 297 AWAIIPHYGWSFSMGSAYQFHSWRVFVIVCALPCVSSVVALTFMPESPRSLLEVGKHDEA 356
Score = 32.3 bits (70), Expect = 4.8
Identities = 22/79 (27%), Positives = 36/79 (45%)
Query: 418 IMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARFFVNISYNATMQWTAEVL 477
+ D +GRK + CM + F L+ FV + C +L+ F + + + AEVL
Sbjct: 211 LADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSYFAEVL 270
Query: 478 PTQVRGSGASVVHICGYIG 496
+ RG S + + IG
Sbjct: 271 AREKRGEHLSWLCMFWMIG 289
>M20681-1|AAB61083.1| 496|Homo sapiens protein ( Human glucose
transporter-like protein-III (GLUT3), complete cds. ).
Length = 496
Score = 38.7 bits (86), Expect = 0.056
Identities = 43/207 (20%), Positives = 78/207 (37%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGI---LTTFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A++ + R +
Sbjct: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + G W +
Sbjct: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLL 187
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T PESPR+LL + EE +IL R+ K
Sbjct: 188 LGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQIL--QRLWGTQDVSQDIQEMKDE 245
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 246 SARMSQEKQVTVLELFRVSSYRQPIII 272
>CR457413-1|CAG33694.1| 496|Homo sapiens ber 3; complete cds, incl.
stopcodon. protein.
Length = 496
Score = 38.7 bits (86), Expect = 0.056
Identities = 43/207 (20%), Positives = 78/207 (37%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGI---LTTFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A++ + R +
Sbjct: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + G W +
Sbjct: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLL 187
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T PESPR+LL + EE +IL R+ K
Sbjct: 188 LGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQIL--QRLWGTQDVSQDIQEMKDE 245
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 246 SARMSQEKQVTVLELFRVSSYRQPIII 272
>BC039196-1|AAH39196.1| 496|Homo sapiens SLC2A3 protein protein.
Length = 496
Score = 38.7 bits (86), Expect = 0.056
Identities = 43/207 (20%), Positives = 78/207 (37%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGI---LTTFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A++ + R +
Sbjct: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + G W +
Sbjct: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLL 187
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T PESPR+LL + EE +IL R+ K
Sbjct: 188 LGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQIL--QRLWGTQDVSQDIQEMKDE 245
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 246 SARMSQEKQVTVLELFRVSSYRQPIII 272
>AY517500-1|AAS76641.1| 234|Homo sapiens putative integral membrane
transport protein protein.
Length = 234
Score = 38.7 bits (86), Expect = 0.056
Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 5/178 (2%)
Query: 192 YGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKY 251
+GR +S L + G FA + RF+AG A + ++ L+++E++T ++
Sbjct: 4 FGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQF 63
Query: 252 KTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLS 311
M + I + ++ + +V S + ES RWL+
Sbjct: 64 CAMALTLTLCAASIGH-ITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLII 122
Query: 312 MGRVEEAINKILTISRINXXXXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPI 365
+ EE + ++ + N K T+ +E + ++ HS E+ + P I
Sbjct: 123 NNKPEEGLKELTKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNI 180
>AK091990-1|BAC03786.1| 234|Homo sapiens protein ( Homo sapiens
cDNA FLJ34671 fis, clone LIVER2001099, moderately
similar to Rattus norvegicus mRNA for putative integral
membrane ).
Length = 234
Score = 38.7 bits (86), Expect = 0.056
Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 5/178 (2%)
Query: 192 YGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLILLEYVTPKY 251
+GR +S L + G FA + RF+AG A + ++ L+++E++T ++
Sbjct: 4 FGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTVLLIVEWITHQF 63
Query: 252 KTMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSXXXXXXXXXXCCIPESPRWLLS 311
M + I + ++ + +V S + ES RWL+
Sbjct: 64 CAMALTLTLCAASIGH-ITLGGLAFVIRDQCILQLVMSAPCFVFFLFSRWLAESARWLII 122
Query: 312 MGRVEEAINKILTISRINXXXXXXXXXXR--FKCTVSKETK--EESHSCLEIFKRPPI 365
+ EE + ++ + N K T+ +E + ++ HS E+ + P I
Sbjct: 123 NNKPEEGLKELTKAAHRNGMKNAEDILTMEVLKSTMKQELEAAQKKHSLCELLRIPNI 180
>AF274892-1|AAF82116.1| 496|Homo sapiens glucose transporter 3
protein.
Length = 496
Score = 38.7 bits (86), Expect = 0.056
Identities = 43/207 (20%), Positives = 78/207 (37%), Gaps = 9/207 (4%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGI---LTTFARNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ GG L A++ + R +
Sbjct: 68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVI 127
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WKTI 284
G+ C + + E + + +A + + G W +
Sbjct: 128 GLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLL 187
Query: 285 SIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCT 344
T PESPR+LL + EE +IL R+ K
Sbjct: 188 LGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQIL--QRLWGTQDVSQDIQEMKDE 245
Query: 345 VSKETKEESHSCLEIFKRPPIRRTFIL 371
++ ++E+ + LE+F+ R+ I+
Sbjct: 246 SARMSQEKQVTVLELFRVSSYRQPIII 272
>BC121804-1|AAI21805.1| 492|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 protein.
Length = 492
Score = 37.9 bits (84), Expect = 0.097
Identities = 45/208 (21%), Positives = 85/208 (40%), Gaps = 11/208 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA---RNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ + +L F+ ++F + RFI
Sbjct: 70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WK-T 283
G+ + + E + + + IA + + G+ W
Sbjct: 130 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 189
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKC 343
+SI+ C PESPR+LL + R EE K + + ++ K
Sbjct: 190 LSIIFIPALLQCIVLPFC-PESPRFLL-INRNEENRAKSV-LKKLRGTADVTHDLQEMKE 246
Query: 344 TVSKETKEESHSCLEIFKRPPIRRTFIL 371
+ +E+ + LE+F+ P R+ ++
Sbjct: 247 ESRQMMREKKVTILELFRSPAYRQPILI 274
>BC118590-1|AAI18591.1| 492|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 protein.
Length = 492
Score = 37.9 bits (84), Expect = 0.097
Identities = 45/208 (21%), Positives = 85/208 (40%), Gaps = 11/208 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA---RNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ + +L F+ ++F + RFI
Sbjct: 70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 129
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WK-T 283
G+ + + E + + + IA + + G+ W
Sbjct: 130 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 189
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKC 343
+SI+ C PESPR+LL + R EE K + + ++ K
Sbjct: 190 LSIIFIPALLQCIVLPFC-PESPRFLL-INRNEENRAKSV-LKKLRGTADVTHDLQEMKE 246
Query: 344 TVSKETKEESHSCLEIFKRPPIRRTFIL 371
+ +E+ + LE+F+ P R+ ++
Sbjct: 247 ESRQMMREKKVTILELFRSPAYRQPILI 274
>BC111015-1|AAI11016.1| 403|Homo sapiens SLC22A17 protein protein.
Length = 403
Score = 37.9 bits (84), Expect = 0.097
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 5/160 (3%)
Query: 413 CV-VAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCT---VLARFFVNISYNA 468
CV + +D GR+ + + M L + +L+ + + + T VL F +
Sbjct: 235 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAIL 294
Query: 469 TMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXX 528
+ AEV+PT VRG G ++ G +G P + ++L
Sbjct: 295 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 354
Query: 529 XXXLPETTKKDIPQTFNEAEELSRNINLWEMPCLSRPKNV 568
LPET +K +P+ + EL R +L P +R +V
Sbjct: 355 IMLLPETKRKLLPEVLRDG-ELCRRPSLLRQPPPTRCDHV 393
Score = 32.7 bits (71), Expect = 3.7
Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 7/149 (4%)
Query: 185 IGWVADRYGRLPAAVYSTLIGCLG--GILTTFARNFTEFSIYRFIAGMAYDNCMMMAYLI 242
+G+ ADR+GR + +G +G G+ A + T RF+ G + YL+
Sbjct: 1 LGYPADRFGR--RGIVLLTLGLVGPCGVGGAAAGSSTGVMALRFLLGFLLAGVDLGVYLM 58
Query: 243 LLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGHWKTIS--IVTSXXXXXXXXXXC 300
LE P + VA +A L ++L W+ + I
Sbjct: 59 RLELCDPTQRLRVA-LAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPG 117
Query: 301 CIPESPRWLLSMGRVEEAINKILTISRIN 329
ES RWL+ ++EEA + + ++ N
Sbjct: 118 LFLESARWLIVKRQIEEAQSVLRILAERN 146
>AJ243653-1|CAC01119.1| 366|Homo sapiens organic cation transporter
protein.
Length = 366
Score = 37.9 bits (84), Expect = 0.097
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 5/160 (3%)
Query: 413 CV-VAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCT---VLARFFVNISYNA 468
CV + +D GR+ + + M L + +L+ + + + T VL F +
Sbjct: 198 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAIL 257
Query: 469 TMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXX 528
+ AEV+PT VRG G ++ G +G P + ++L
Sbjct: 258 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 317
Query: 529 XXXLPETTKKDIPQTFNEAEELSRNINLWEMPCLSRPKNV 568
LPET +K +P+ + EL R +L P +R +V
Sbjct: 318 IMLLPETKRKLLPEVLRDG-ELCRRPSLLRQPPPTRCDHV 356
>AJ243122-1|CAC17762.1| 366|Homo sapiens organic cation transporter
protein.
Length = 366
Score = 37.9 bits (84), Expect = 0.097
Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 5/160 (3%)
Query: 413 CV-VAFIMDWMGRKWVTIGCMMLCSVFTLLTVFVGSGVPSVMCT---VLARFFVNISYNA 468
CV + +D GR+ + + M L + +L+ + + + T VL F +
Sbjct: 198 CVFLGVTVDRFGRRGILLLSMTLTGIASLVLLGLWDYLNEAAITTFSVLGLFSSQAAAIL 257
Query: 469 TMQWTAEVLPTQVRGSGASVVHICGYIGTALSPYIVYLQIYISWLPXXXXXXXXXXXXXX 528
+ AEV+PT VRG G ++ G +G P + ++L
Sbjct: 258 STLLAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMGHGAFLQHVVLAACALLCILS 317
Query: 529 XXXLPETTKKDIPQTFNEAEELSRNINLWEMPCLSRPKNV 568
LPET +K +P+ + EL R +L P +R +V
Sbjct: 318 IMLLPETKRKLLPEVLRDG-ELCRRPSLLRQPPPTRCDHV 356
>AB208987-1|BAD92224.1| 517|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 1 variant
protein.
Length = 517
Score = 37.9 bits (84), Expect = 0.097
Identities = 45/208 (21%), Positives = 85/208 (40%), Gaps = 11/208 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFA---RNFTEFSIYRFIA 228
A+F VG +IG F +G +R+GR + + L+ + +L F+ ++F + RFI
Sbjct: 95 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFII 154
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPW-ISLACGH---WK-T 283
G+ + + E + + + IA + + G+ W
Sbjct: 155 GVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLL 214
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKC 343
+SI+ C PESPR+LL + R EE K + + ++ K
Sbjct: 215 LSIIFIPALLQCIVLPFC-PESPRFLL-INRNEENRAKSV-LKKLRGTADVTHDLQEMKE 271
Query: 344 TVSKETKEESHSCLEIFKRPPIRRTFIL 371
+ +E+ + LE+F+ P R+ ++
Sbjct: 272 ESRQMMREKKVTILELFRSPAYRQPILI 299
>BC117119-1|AAI17120.1| 629|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 13 protein.
Length = 629
Score = 37.5 bits (83), Expect = 0.13
Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 176 VGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNC 235
V ++ GG L G +GR A + ++ + G + A N R + G+
Sbjct: 114 VSALAGGALNGV----FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIA 169
Query: 236 MMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGH-----WKTISIVTSX 290
M + + E P + + + LF T + A + W+ + + +
Sbjct: 170 SMTVPVYIAEVSPPNLRGRLVTIN-TLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAV 228
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETK 350
+PESPRWL+ G+ ++A +IL+ R N K + +E K
Sbjct: 229 PAVIQFFGFLFLPESPRWLIQKGQTQKA-RRILSQMRGNQTIDEEYDS--IKNNIEEEEK 285
Query: 351 EESHS---CLEIFKRPPIRRTFILMC 373
E + + PP RR I+ C
Sbjct: 286 EVGSAGPVICRMLSYPPTRRALIVGC 311
>BC117117-1|AAI17118.1| 629|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 13 protein.
Length = 629
Score = 37.5 bits (83), Expect = 0.13
Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 176 VGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNC 235
V ++ GG L G +GR A + ++ + G + A N R + G+
Sbjct: 114 VSALAGGALNGV----FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIA 169
Query: 236 MMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGH-----WKTISIVTSX 290
M + + E P + + + LF T + A + W+ + + +
Sbjct: 170 SMTVPVYIAEVSPPNLRGRLVTIN-TLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAV 228
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETK 350
+PESPRWL+ G+ ++A +IL+ R N K + +E K
Sbjct: 229 PAVIQFFGFLFLPESPRWLIQKGQTQKA-RRILSQMRGNQTIDEEYDS--IKNNIEEEEK 285
Query: 351 EESHS---CLEIFKRPPIRRTFILMC 373
E + + PP RR I+ C
Sbjct: 286 EVGSAGPVICRMLSYPPTRRALIVGC 311
>BC047507-1|AAH47507.1| 338|Homo sapiens SLC2A13 protein protein.
Length = 338
Score = 37.5 bits (83), Expect = 0.13
Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 176 VGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNC 235
V ++ GG L G +GR A + ++ + G + A N R + G+
Sbjct: 114 VSALAGGALNGV----FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIA 169
Query: 236 MMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGH-----WKTISIVTSX 290
M + + E P + + + LF T + A + W+ + + +
Sbjct: 170 SMTVPVYIAEVSPPNLRGRLVTIN-TLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAV 228
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETK 350
+PESPRWL+ G+ ++A +IL+ R N K + +E K
Sbjct: 229 PAVIQFFGFLFLPESPRWLIQKGQTQKA-RRILSQMRGNQTIDEEYDS--IKNNIEEEEK 285
Query: 351 EESHS---CLEIFKRPPIRRTFILMC 373
E + + PP RR I+ C
Sbjct: 286 EVGSAGPVICRMLSYPPTRRALIVGC 311
>U11843-1|AAB60641.1| 481|Homo sapiens fructose transporter
protein.
Length = 481
Score = 37.1 bits (82), Expect = 0.17
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFS---IYRFIA 228
++F G IG L+G + +++GR A +++ + + IL +R T F I R +
Sbjct: 56 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 115
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLA-----CGHWKT 283
G+ + + L E + PK + LF T + L W
Sbjct: 116 GICAGVSSNVVPMYLGE-LAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPI 174
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISR 327
+ +T PESPR+LL + E A K L R
Sbjct: 175 LLGLTGVGAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR 218
>AJ315644-1|CAC51116.1| 629|Homo sapiens proton myo-inositol
transporter protein.
Length = 629
Score = 37.1 bits (82), Expect = 0.17
Identities = 44/206 (21%), Positives = 76/206 (36%), Gaps = 16/206 (7%)
Query: 176 VGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMAYDNC 235
V ++ GG L G +GR A + ++ + G + A N R + G+
Sbjct: 114 VSALAGGALNGV----FGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIA 169
Query: 236 MMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLACGH-----WKTISIVTSX 290
M + + E P + + + LF T + A + W+ + +
Sbjct: 170 SMTVPVYIAEVSPPNLRGRLVTIN-TLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAXV 228
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISRINXXXXXXXXXXRFKCTVSKETK 350
+PESPRWL+ G+ ++A +IL+ R N K + +E K
Sbjct: 229 PAVIQFFGFLFLPESPRWLIQKGQTQKA-RRILSQMRGNQTIDEEYDS--IKNNIEEEEK 285
Query: 351 EESHS---CLEIFKRPPIRRTFILMC 373
E + + PP RR I+ C
Sbjct: 286 EVGSAGPVICRMLSYPPTRRALIVGC 311
>M91463-1|AAA52569.1| 505|Homo sapiens glucose transporter protein.
Length = 505
Score = 36.7 bits (81), Expect = 0.22
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAGMAYDNCMMM 238
RF+ G AY + M
Sbjct: 142 RFLIG-AYSGLVPM 154
>M55531-1|AAA52570.1| 501|Homo sapiens GLUT5 protein protein.
Length = 501
Score = 36.7 bits (81), Expect = 0.22
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFS---IYRFIA 228
++F G IG L+G + +++GR A +++ + + IL +R T F I R +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLA-----CGHWKT 283
G+ + + L E + PK + LF T + L W
Sbjct: 136 GICAGVSSNVVPMYLGE-LAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPI 194
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISR 327
+ +T PESPR+LL + E A K L R
Sbjct: 195 LLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR 238
>BC001820-1|AAH01820.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 36.7 bits (81), Expect = 0.22
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFS---IYRFIA 228
++F G IG L+G + +++GR A +++ + + IL +R T F I R +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLA-----CGHWKT 283
G+ + + L E + PK + LF T + L W
Sbjct: 136 GICAGVSSNVVPMYLGE-LAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPI 194
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISR 327
+ +T PESPR+LL + E A K L R
Sbjct: 195 LLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR 238
>BC001692-1|AAH01692.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 36.7 bits (81), Expect = 0.22
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFS---IYRFIA 228
++F G IG L+G + +++GR A +++ + + IL +R T F I R +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLA-----CGHWKT 283
G+ + + L E + PK + LF T + L W
Sbjct: 136 GICAGVSSNVVPMYLGE-LAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPI 194
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISR 327
+ +T PESPR+LL + E A K L R
Sbjct: 195 LLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR 238
>AL158048-3|CAI23458.1| 501|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 501
Score = 36.7 bits (81), Expect = 0.22
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 9/164 (5%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFS---IYRFIA 228
++F G IG L+G + +++GR A +++ + + IL +R T F I R +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLV 135
Query: 229 GMAYDNCMMMAYLILLEYVTPKYKTMVANMAFALFYTSFTIAMPWISLA-----CGHWKT 283
G+ + + L E + PK + LF T + L W
Sbjct: 136 GICAGVSSNVVPMYLGE-LAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPI 194
Query: 284 ISIVTSXXXXXXXXXXCCIPESPRWLLSMGRVEEAINKILTISR 327
+ +T PESPR+LL + E A K L R
Sbjct: 195 LLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLR 238
>M20747-1|AAA59189.1| 509|Homo sapiens GLUT4 protein.
Length = 509
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>BC126164-1|AAI26165.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>BC113592-1|AAI13593.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>BC069621-1|AAH69621.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>BC069615-1|AAH69615.1| 509|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 4 protein.
Length = 509
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>BC034387-1|AAH34387.1| 415|Homo sapiens SLC2A4 protein protein.
Length = 415
Score = 35.5 bits (78), Expect = 0.52
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 168 ATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIY--- 224
A + A+F VG +I FLIG ++ GR A + + ++ LGG L A + +
Sbjct: 82 ALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141
Query: 225 RFIAG 229
RF+ G
Sbjct: 142 RFLIG 146
>J03810-1|AAA59514.1| 524|Homo sapiens GLUT2 protein.
Length = 524
Score = 34.7 bits (76), Expect = 0.91
Identities = 13/43 (30%), Positives = 24/43 (55%)
Query: 174 FFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFAR 216
F VG + F GW+ D GR+ A + + ++ +G +L F++
Sbjct: 104 FAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSK 146
>BC036796-1|AAH36796.1| 340|Homo sapiens SVOP-like protein.
Length = 340
Score = 34.7 bits (76), Expect = 0.91
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 419 MDWMGRKW---VTIGCMMLCSVFTLLTVFVGSGVPSVMCTVLARFFVNISYNATMQWTAE 475
++++GR+ +T+GC L F LL S + + R V ++N +TAE
Sbjct: 213 INFLGRRLSLSITMGCTAL---FFLLLNICTSSAGLIGFLFMLRALVAANFNTVYIYTAE 269
Query: 476 VLPTQVRGSGASVVHICGYIGTALSPYI 503
V PT +R G IG ++P+I
Sbjct: 270 VYPTTMRALGMGTSGSLCRIGAMVAPFI 297
>AJ251884-1|CAB96132.1| 143|Homo sapiens extraneuronal monoamine
transporter (EMT) protein.
Length = 143
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/59 (28%), Positives = 28/59 (47%)
Query: 32 NFDELLIAAGEFGIYQILLFFATSPFFLFGVFVYYSQMFITEPSPNHWCWVPELANLTD 90
+FDE L GEFG +Q +F + F++ +F+ ++WC P A L +
Sbjct: 3 SFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALAE 61
>Y17803-1|CAB96996.1| 507|Homo sapiens facilitataive glucose
transporter g (GLUT6) protein.
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>BC013740-1|AAH13740.1| 507|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 6 protein.
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AL593848-7|CAI17254.1| 445|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 6 protein.
Length = 445
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AL593848-6|CAI17253.1| 507|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 6 protein.
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AK222919-1|BAD96639.1| 507|Homo sapiens solute carrier family 2
(facilitated glucose transporter), member 6 variant
protein.
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AK074927-1|BAC11297.1| 507|Homo sapiens protein ( Homo sapiens
cDNA FLJ90446 fis, clone NT2RP3001195, highly similar to
Solute carrier family 2, facilitated glucosetransporter,
member ).
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AK074836-1|BAC11235.1| 445|Homo sapiens r-4. protein.
Length = 445
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>AJ011372-1|CAB66155.1| 507|Homo sapiens sugar transporter protein.
Length = 507
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/152 (21%), Positives = 59/152 (38%), Gaps = 4/152 (2%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSIYRFIAGMA 231
++F +G+ GG + D GR + ++S + G L A + R + G A
Sbjct: 86 SVFTLGAAAGGLSAMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFA 145
Query: 232 YDNCMMMAYLILLEYVTPKYK-TMVANMAFALFYTSFTIAMPWISLACGHWKTISIVTSX 290
+ + E P + + A + S ++ + L W+ +++
Sbjct: 146 GGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGLLLP---WRWLAVAGEA 202
Query: 291 XXXXXXXXXCCIPESPRWLLSMGRVEEAINKI 322
+P SPR+LLS GR EEA+ +
Sbjct: 203 PVLIMILLLSFMPNSPRFLLSRGRDEEALRAL 234
>BC030693-1|AAH30693.1| 478|Homo sapiens solute carrier family 16,
member 7 (monocarboxylic acid transporter 2) protein.
Length = 478
Score = 32.7 bits (71), Expect = 3.7
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 143 FNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYST 202
F + + + T SE+ WI + A+ + G + L+ ++YG P +
Sbjct: 44 FKEIQQIFHTTYSEIAWI------SSIMLAVMYAGGPVSSVLV----NKYGSRPVVIAGG 93
Query: 203 LIGCLGGILTTFARNFTE-FSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
L+ CLG +L +F+ + + + FI G+ + A I+ +Y K + M +A A
Sbjct: 94 LLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRK-RPMANGLAMA 152
>AF058056-1|AAC13721.1| 478|Homo sapiens monocarboxylate
transporter 2 protein.
Length = 478
Score = 32.7 bits (71), Expect = 3.7
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 143 FNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYST 202
F + + + T SE+ WI + A+ + G + L+ ++YG P +
Sbjct: 44 FKEIQQIFHTTYSEIAWI------SSIMLAVMYAGGPVSSVLV----NKYGSRPVVIAGG 93
Query: 203 LIGCLGGILTTFARNFTE-FSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
L+ CLG +L +F+ + + + FI G+ + A I+ +Y K + M +A A
Sbjct: 94 LLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRK-RPMANGLAMA 152
>AF049608-1|AAC70919.1| 478|Homo sapiens monocarboxylate
transporter 2 protein.
Length = 478
Score = 32.7 bits (71), Expect = 3.7
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 12/120 (10%)
Query: 143 FNKTEIPYPTITSEMDWICDRGSYQATAQALFFVGSIIGGFLIGWVADRYGRLPAAVYST 202
F + + + T SE+ WI + A+ + G + L+ ++YG P +
Sbjct: 44 FKEIQQIFHTTYSEIAWI------SSIMLAVMYAGGPVSSVLV----NKYGSRPVVIAGG 93
Query: 203 LIGCLGGILTTFARNFTE-FSIYRFIAGMAYDNCMMMAYLILLEYVTPKYKTMVANMAFA 261
L+ CLG +L +F+ + + + FI G+ + A I+ +Y K + M +A A
Sbjct: 94 LLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRK-RPMANGLAMA 152
>BC035878-1|AAH35878.1| 244|Homo sapiens SLC2A5 protein protein.
Length = 244
Score = 31.5 bits (68), Expect = 8.4
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSI 223
++F G IG L+G + +++GR A +++ + + IL +R T F +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127
>AL158048-2|CAI23457.1| 244|Homo sapiens solute carrier family 2
(facilitated glucose/fructose transporter), member 5
protein.
Length = 244
Score = 31.5 bits (68), Expect = 8.4
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSI 223
++F G IG L+G + +++GR A +++ + + IL +R T F +
Sbjct: 76 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 127
>AF479408-1|AAL87107.1| 107|Homo sapiens glucose transporter-like
protein 5 protein.
Length = 107
Score = 31.5 bits (68), Expect = 8.4
Identities = 14/52 (26%), Positives = 28/52 (53%)
Query: 172 ALFFVGSIIGGFLIGWVADRYGRLPAAVYSTLIGCLGGILTTFARNFTEFSI 223
++F G IG L+G + +++GR A +++ + + IL +R T F +
Sbjct: 11 SMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFEL 62
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.326 0.138 0.447
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,518,902
Number of Sequences: 224733
Number of extensions: 3152545
Number of successful extensions: 9980
Number of sequences better than 10.0: 179
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 9375
Number of HSP's gapped (non-prelim): 285
length of query: 579
length of database: 73,234,838
effective HSP length: 94
effective length of query: 485
effective length of database: 52,109,936
effective search space: 25273318960
effective search space used: 25273318960
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 68 (31.5 bits)
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