Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002519-TA|BGIBMGA002519-PA|IPR000152|Aspartic acid and
asparagine hydroxylation site, IPR000859|CUB, IPR013032|EGF-like
region, IPR000742|EGF-like, type 3, IPR001881|EGF-like
calcium-binding, IPR006210|EGF, IPR013091|EGF calcium-binding
(642 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC113577-1|AAI13578.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
BC112366-1|AAI12367.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
BC112341-1|AAI12342.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
AL391136-1|CAH72234.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
AL138765-2|CAI13580.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
AL136181-1|CAH72983.1| 1015|Homo sapiens tolloid-like 2 protein. 669 0.0
AF059516-1|AAD42979.1| 1015|Homo sapiens tolloid-like 2 protein ... 669 0.0
AB023149-1|BAA76776.2| 1078|Homo sapiens KIAA0932 protein protein. 669 0.0
U91963-1|AAB93878.1| 1013|Homo sapiens tolloid-like protein prot... 667 0.0
AF282732-1|AAF86287.1| 1013|Homo sapiens tolloid-like protein pr... 667 0.0
U50330-1|AAA93462.1| 986|Homo sapiens procollagen C-proteinase ... 653 0.0
M22488-1|AAA51833.1| 730|Homo sapiens BMP1 protein. 339 2e-92
AB209590-1|BAD92827.1| 803|Homo sapiens bone morphogenetic prot... 339 2e-92
Y08725-1|CAA69975.1| 717|Homo sapiens BMP1-6 protein. 338 3e-92
L35279-1|AAC41710.1| 284|Homo sapiens bone morphogenetic protei... 320 7e-87
Y08724-1|CAA69974.1| 622|Homo sapiens BMP1-5 protein. 225 5e-58
BC013871-1|AAH13871.1| 593|Homo sapiens TLL2 protein protein. 170 1e-41
AY210418-1|AAO34701.1| 3487|Homo sapiens CUB and sushi multiple ... 164 7e-40
AL355178-1|CAI23434.1| 1167|Homo sapiens CUB and Sushi multiple ... 164 7e-40
AL161643-1|CAI23498.1| 1167|Homo sapiens CUB and Sushi multiple ... 164 7e-40
AB212622-1|BAD97692.1| 3631|Homo sapiens CSMD2 protein protein. 164 7e-40
AB209502-1|BAD92739.1| 2966|Homo sapiens CUB and Sushi multiple ... 164 7e-40
AK127722-1|BAC87101.1| 1167|Homo sapiens protein ( Homo sapiens ... 164 1e-39
AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple ... 161 7e-39
AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2... 161 7e-39
AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1... 161 7e-39
AY358174-1|AAQ88541.1| 1169|Homo sapiens CSMD1 protein. 157 1e-37
AK126936-1|BAC86754.1| 783|Homo sapiens protein ( Homo sapiens ... 157 1e-37
AB067477-1|BAB67783.1| 1048|Homo sapiens KIAA1890 protein protein. 157 1e-37
AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein. 157 1e-37
AB007617-1|BAA89206.1| 699|Homo sapiens MASP/P100 protein. 157 1e-37
D61695-1|BAA34864.1| 699|Homo sapiens mannose-binding protein a... 155 3e-37
D28593-1|BAA05928.1| 699|Homo sapiens MASP protein. 155 3e-37
D17525-1|BAA04477.1| 699|Homo sapiens precursor of P100 serine ... 155 3e-37
BC106946-1|AAI06947.1| 728|Homo sapiens mannan-binding lectin s... 155 3e-37
BC106945-1|AAI06946.1| 728|Homo sapiens mannan-binding lectin s... 155 3e-37
BC039724-1|AAH39724.1| 488|Homo sapiens MASP1 protein protein. 155 3e-37
AF284421-1|AAK84071.1| 728|Homo sapiens complement factor MASP-... 155 3e-37
AK055132-1|BAB70859.1| 579|Homo sapiens protein ( Homo sapiens ... 153 2e-36
AJ862823-1|CAH93521.1| 578|Homo sapiens membrane frizzled relat... 153 2e-36
AB055505-1|BAB39771.1| 579|Homo sapiens membrane-type frizzled-... 153 2e-36
AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple ... 152 4e-36
AF333704-1|AAK73475.2| 3566|Homo sapiens CUB and sushi multiple ... 152 4e-36
Y18287-2|CAB50735.1| 686|Homo sapiens MASP-2 protein. 147 9e-35
Y18286-2|CAB50733.1| 686|Homo sapiens MASP-2 protein protein. 147 9e-35
Y09926-1|CAA71059.1| 686|Homo sapiens MASP-2 protein protein. 147 9e-35
X98400-1|CAA67050.1| 686|Homo sapiens mannan-binding lectin-ass... 147 9e-35
AL109811-4|CAI22102.1| 686|Homo sapiens mannan-binding lectin s... 147 9e-35
AF321562-1|AAG50274.1| 686|Homo sapiens MBL-associated serine p... 147 9e-35
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact... 140 1e-32
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact... 140 1e-32
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact... 140 1e-32
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami... 139 2e-32
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re... 139 2e-32
AB209880-1|BAD93117.1| 1327|Homo sapiens cubilin variant protein. 139 3e-32
BC033205-1|AAH33205.1| 449|Homo sapiens procollagen C-endopepti... 138 7e-32
BC000574-1|AAH00574.1| 449|Homo sapiens procollagen C-endopepti... 138 7e-32
AF083655-1|AAD16041.1| 449|Homo sapiens procollagen C-proteinas... 138 7e-32
AF053356-10|AAC78800.1| 449|Homo sapiens PCOLCE protein. 138 7e-32
AB008549-1|BAA23281.1| 449|Homo sapiens type 1 procollagen C-pr... 138 7e-32
L33799-1|AAA61949.1| 449|Homo sapiens procollagen C-proteinase ... 137 1e-31
AL357673-1|CAH73896.1| 449|Homo sapiens novel transcript protein. 135 5e-31
CR536570-1|CAG38807.1| 415|Homo sapiens PCOLCE2 protein. 128 5e-29
AY358557-1|AAQ88921.1| 415|Homo sapiens PCOLCE2 protein. 128 5e-29
AY035400-1|AAK63128.1| 415|Homo sapiens procollagen C-proteinas... 128 5e-29
AF098269-1|AAF04621.1| 415|Homo sapiens procollagen C-terminal ... 128 5e-29
AK223633-1|BAD97353.1| 415|Homo sapiens procollagen C-endopepti... 128 6e-29
X06596-1|CAA29817.1| 688|Homo sapiens complement protein C1s pr... 127 1e-28
M18767-1|AAA51853.1| 688|Homo sapiens C1S protein. 127 1e-28
J04080-1|AAA51852.1| 688|Homo sapiens C1S protein. 127 1e-28
BC056903-1|AAH56903.1| 688|Homo sapiens complement component 1,... 127 1e-28
AB009076-1|BAA86864.1| 329|Homo sapiens complement C1s protein. 127 1e-28
M14058-1|AAA51851.1| 705|Homo sapiens C1R protein. 125 6e-28
X04701-1|CAA28407.1| 705|Homo sapiens protein ( Human mRNA for ... 124 1e-27
BC035220-1|AAH35220.1| 705|Homo sapiens complement component 1,... 124 1e-27
AB083037-1|BAC19850.2| 705|Homo sapiens r subcomponent of compl... 124 1e-27
AK222481-1|BAD96201.1| 705|Homo sapiens complement component 1,... 124 1e-27
AL355178-2|CAI23435.1| 426|Homo sapiens CUB and Sushi multiple ... 122 3e-27
AK222491-1|BAD96211.1| 705|Homo sapiens complement component 1,... 122 5e-27
BT006995-1|AAP35641.1| 644|Homo sapiens neuropilin 1 protein. 118 8e-26
BC007737-1|AAH07737.1| 609|Homo sapiens neuropilin 1 protein. 118 8e-26
BC007533-1|AAH07533.1| 644|Homo sapiens neuropilin 1 protein. 118 8e-26
AY249243-1|AAP80144.1| 906|Homo sapiens neuropilin-1 protein. 118 8e-26
AF280547-1|AAG41406.1| 704|Homo sapiens neuropilin-1 soluble is... 118 8e-26
AF268691-1|AAQ14300.1| 641|Homo sapiens muscle type neuropilin ... 118 8e-26
AF145712-1|AAF44344.1| 644|Homo sapiens soluble neuropilin-1 pr... 118 8e-26
AF018956-1|AAC51759.1| 923|Homo sapiens neuropilin protein. 118 8e-26
AF016050-1|AAC12921.1| 923|Homo sapiens vascular endothelial ce... 118 8e-26
AL353600-4|CAI17000.1| 704|Homo sapiens neuropilin 1 protein. 116 3e-25
AL353600-3|CAI16999.1| 609|Homo sapiens neuropilin 1 protein. 116 3e-25
AL353600-2|CAI16998.1| 644|Homo sapiens neuropilin 1 protein. 116 3e-25
AL353600-1|CAI16997.1| 923|Homo sapiens neuropilin 1 protein. 116 3e-25
AL121748-4|CAI40251.1| 704|Homo sapiens neuropilin 1 protein. 116 3e-25
AL121748-3|CAI40249.1| 609|Homo sapiens neuropilin 1 protein. 116 3e-25
AL121748-2|CAI40250.1| 644|Homo sapiens neuropilin 1 protein. 116 3e-25
AL121748-1|CAI40248.1| 923|Homo sapiens neuropilin 1 protein. 116 3e-25
BX510902-1|CAD91133.1| 923|Homo sapiens hypothetical protein pr... 115 4e-25
BC117413-1|AAI17414.1| 926|Homo sapiens neuropilin 2 protein. 110 1e-23
BC104770-1|AAI04771.1| 901|Homo sapiens neuropilin 2 protein. 110 1e-23
BC101525-1|AAI01526.1| 901|Homo sapiens neuropilin 2 protein. 110 1e-23
AF281074-4|AAG41899.1| 901|Homo sapiens neuropilin-2b(0) protein. 110 1e-23
AF281074-3|AAG41900.1| 906|Homo sapiens neuropilin-2b(5) protein. 110 1e-23
AF281074-2|AAG41897.1| 926|Homo sapiens neuropilin-2a(17) protein. 110 1e-23
AF281074-1|AAG41898.1| 931|Homo sapiens neuropilin-2a(22) protein. 110 1e-23
AF280546-1|AAG41405.1| 555|Homo sapiens neuropilin-2 soluble is... 110 1e-23
AF280545-1|AAG41404.1| 906|Homo sapiens neuropilin-2b(5) protein. 110 1e-23
AF280544-1|AAG41403.1| 901|Homo sapiens neuropilin-2b(O) protein. 110 1e-23
AF022860-1|AAC51789.1| 926|Homo sapiens neuropilin-2(a17) protein. 110 1e-23
AF022859-1|AAC51788.1| 909|Homo sapiens neuropilin-2(a0) protein. 110 1e-23
AF016098-1|AAC12922.1| 931|Homo sapiens vascular endothelial ce... 110 1e-23
AC007362-1|AAX93216.1| 808|Homo sapiens unknown protein. 110 2e-23
BX537423-1|CAD97665.1| 931|Homo sapiens hypothetical protein pr... 107 2e-22
AB209641-1|BAD92878.1| 890|Homo sapiens Neuropilin-1 precursor ... 106 3e-22
Y18287-1|CAB50734.1| 185|Homo sapiens MAp19 protein. 103 2e-21
Y18286-1|CAB50732.1| 185|Homo sapiens MAp19 protein protein. 103 2e-21
Y18284-1|CAB50731.1| 185|Homo sapiens mannose binding lectin-as... 103 2e-21
Y18283-1|CAB50730.1| 185|Homo sapiens mannose binding lectin-as... 103 2e-21
Y18282-1|CAB50729.1| 175|Homo sapiens mannose binding lectin-as... 103 2e-21
Y18281-1|CAB50728.1| 185|Homo sapiens mannose binding lectin-as... 103 2e-21
AL109811-5|CAI22103.1| 185|Homo sapiens mannan-binding lectin s... 103 2e-21
AF321558-1|AAG50275.1| 185|Homo sapiens MBL-associated protein ... 103 2e-21
AB033742-1|BAA85658.1| 185|Homo sapiens small MBL-associated pr... 103 2e-21
AB008047-1|BAA78616.1| 185|Homo sapiens small MBL-associated pr... 103 2e-21
BC140003-1|AAI40004.1| 316|Homo sapiens Unknown (protein for MG... 101 6e-21
AB033742-2|BAA85659.1| 181|Homo sapiens MBL-associated serine p... 101 8e-21
AF448838-1|AAM18026.1| 533|Homo sapiens neuropilin and tolloid ... 97 2e-19
AK122760-1|BAC85509.1| 157|Homo sapiens protein ( Homo sapiens ... 95 7e-19
AJ297949-2|CAC17139.1| 136|Homo sapiens MASP-2 protein protein. 95 9e-19
BC050329-1|AAH50329.1| 533|Homo sapiens NETO1 protein protein. 93 2e-18
AY358718-1|AAQ89080.1| 525|Homo sapiens Neto2 protein. 93 3e-18
AK074937-1|BAC11303.1| 525|Homo sapiens protein ( Homo sapiens ... 93 3e-18
BC108727-1|AAI08728.1| 329|Homo sapiens Unknown (protein for IM... 92 5e-18
AY358556-1|AAQ88920.1| 607|Homo sapiens ERG-1 protein. 89 4e-17
AY260047-1|AAP15458.1| 607|Homo sapiens transmembrane protein U... 89 4e-17
AL359747-4|CAH70006.1| 607|Homo sapiens CUB and zona pellucida-... 89 4e-17
BC089434-1|AAH89434.1| 737|Homo sapiens regeneration associated... 86 3e-16
AY358346-1|AAQ88712.1| 720|Homo sapiens ELGC699 protein. 86 3e-16
BX640988-1|CAE45995.1| 705|Homo sapiens hypothetical protein pr... 85 6e-16
AL603764-10|CAI14496.1| 2413|Homo sapiens deleted in malignant b... 85 6e-16
AL603764-9|CAI14495.1| 2413|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-8|CAI14488.1| 2413|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-7|CAI14494.1| 2412|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-6|CAI14493.1| 1785|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-5|CAI14492.1| 2403|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-4|CAI14491.1| 1785|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-3|CAI14490.1| 1785|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-2|CAI14489.1| 2542|Homo sapiens deleted in malignant br... 85 6e-16
AL603764-1|CAI14487.1| 2413|Homo sapiens deleted in malignant br... 85 6e-16
AK126252-1|BAC86505.1| 386|Homo sapiens protein ( Homo sapiens ... 85 6e-16
AK027841-1|BAB55404.1| 737|Homo sapiens protein ( Homo sapiens ... 85 6e-16
AJ297935-1|CAC44122.1| 2413|Homo sapiens DMBT1/8kb.2 protein pro... 85 6e-16
AJ243224-1|CAB63942.1| 2403|Homo sapiens DMBT1/8kb.1 protein pro... 85 6e-16
AJ243212-1|CAB56155.1| 2412|Homo sapiens DMBT1/8kb.2 protein pro... 85 6e-16
AJ243211-1|CAB63941.1| 2426|Homo sapiens DMBT1 prototype protein. 85 6e-16
AJ000342-1|CAA04019.1| 1785|Homo sapiens DMBT1/6kb.1 protein pro... 85 6e-16
AF159456-1|AAD49696.1| 2413|Homo sapiens gp-340 variant protein ... 85 6e-16
AB020851-1|BAA78577.1| 1785|Homo sapiens DMBT1 protein. 85 6e-16
BC032109-1|AAH32109.1| 859|Homo sapiens low density lipoprotein... 79 4e-14
AF166350-1|AAD44360.1| 859|Homo sapiens ST7 protein protein. 79 4e-14
AF448839-1|AAM18027.1| 156|Homo sapiens neuropilin and tolloid ... 79 6e-14
D29810-1|BAA18909.1| 364|Homo sapiens unknown protein. 78 8e-14
BC029658-1|AAH29658.1| 743|Homo sapiens DCBLD2 protein protein. 78 8e-14
AF387547-1|AAL30178.1| 775|Homo sapiens endothelial and smooth ... 78 8e-14
AB073146-1|BAB91138.1| 775|Homo sapiens CLCP1 protein. 78 8e-14
M31165-1|AAB00792.1| 277|Homo sapiens adhesion receptor CD44 pr... 77 1e-13
BC030645-1|AAH30645.1| 364|Homo sapiens platelet derived growth... 77 1e-13
BC030205-1|AAH30205.1| 277|Homo sapiens tumor necrosis factor, ... 77 1e-13
AY359116-1|AAQ89474.1| 364|Homo sapiens SCDGF-B protein. 77 1e-13
AY027518-1|AAK20082.1| 364|Homo sapiens iris-expressed growth f... 77 1e-13
AY027517-1|AAK20081.1| 370|Homo sapiens iris-expressed growth f... 77 1e-13
AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AJ421518-1|CAD13434.1| 277|Homo sapiens TSG-6 protein protein. 77 1e-13
AJ419936-1|CAD12353.1| 277|Homo sapiens TSG-6 protein protein. 77 1e-13
AF336376-1|AAK56136.1| 370|Homo sapiens platelet-derived growth... 77 1e-13
AF335584-1|AAK38840.1| 370|Homo sapiens platelet-derived growth... 77 1e-13
AC009311-2|AAY15067.1| 277|Homo sapiens unknown protein. 77 1e-13
AB033832-1|BAB18903.1| 370|Homo sapiens spinal cord-derived gro... 77 1e-13
AF057145-1|AAG15395.1| 855|Homo sapiens serine protease TADG15 ... 77 2e-13
BC030532-1|AAH30532.1| 855|Homo sapiens suppression of tumorige... 76 3e-13
AF133086-1|AAF00109.1| 855|Homo sapiens membrane-type serine pr... 76 3e-13
AF118224-1|AAD42765.2| 855|Homo sapiens matriptase protein. 76 3e-13
AB030036-1|BAB20376.1| 855|Homo sapiens prostamin protein. 76 3e-13
BX640971-1|CAE45986.1| 1221|Homo sapiens hypothetical protein pr... 75 6e-13
BX640873-1|CAE45930.1| 1198|Homo sapiens hypothetical protein pr... 75 6e-13
BC075798-1|AAH75798.1| 1222|Homo sapiens GPR126 protein protein. 75 6e-13
AF216967-1|AAO13250.1| 1222|Homo sapiens putative vascular induc... 75 6e-13
AB183549-1|BAD27574.1| 1222|Homo sapiens developmentally regulat... 75 6e-13
AB183548-1|BAD27573.1| 1250|Homo sapiens developmentally regulat... 75 6e-13
AB183547-1|BAD27572.1| 1193|Homo sapiens developmentally regulat... 75 6e-13
AB183546-1|BAD27571.1| 1221|Homo sapiens developmentally regulat... 75 6e-13
Y19124-1|CAB65555.1| 1019|Homo sapiens enteropeptidase protein. 72 5e-12
U09860-1|AAC50138.1| 1019|Homo sapiens enterokinase protein. 72 5e-12
BC111749-1|AAI11750.1| 1019|Homo sapiens protease, serine, 7 (en... 72 5e-12
AL163217-2|CAB90389.1| 904|Homo sapiens human enterokinase; EC ... 72 5e-12
CR456574-1|CAG30460.1| 948|Homo sapiens SEZ6L protein. 71 2e-11
BC126115-1|AAI26116.1| 1024|Homo sapiens seizure related 6 homol... 71 2e-11
BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein. 71 2e-11
AY358405-1|AAQ88771.1| 1023|Homo sapiens SEZ6L protein. 71 2e-11
AL078460-1|CAI20266.1| 949|Homo sapiens seizure related 6 homol... 71 2e-11
AL050253-1|CAB43355.1| 792|Homo sapiens hypothetical protein pr... 71 2e-11
AL035545-1|CAB37431.1| 716|Homo sapiens hypothetical protein pr... 71 2e-11
AL023513-2|CAI19980.1| 949|Homo sapiens seizure related 6 homol... 71 2e-11
AL022337-1|CAI17997.1| 949|Homo sapiens seizure related 6 homol... 71 2e-11
AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens ... 71 2e-11
AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein. 71 2e-11
AB041736-1|BAB40970.1| 1024|Homo sapiens SEZ6L protein. 71 2e-11
AB023144-1|BAA76771.2| 1001|Homo sapiens KIAA0927 protein protein. 71 2e-11
Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA seque... 70 2e-11
Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA seque... 70 2e-11
BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein. 70 2e-11
BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein. 70 2e-11
AF525689-1|AAN77133.1| 988|Homo sapiens signal peptide-CUB-EGF-... 70 2e-11
U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein. 69 5e-11
AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital... 69 5e-11
AL834404-1|CAD39066.1| 451|Homo sapiens hypothetical protein pr... 68 1e-10
X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein. 67 2e-10
Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA seque... 66 3e-10
BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB dom... 66 3e-10
AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and... 66 3e-10
AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing ... 66 3e-10
AK223620-1|BAD97340.1| 994|Homo sapiens seizure related 6 homol... 66 5e-10
AK091522-1|BAC03684.1| 869|Homo sapiens protein ( Homo sapiens ... 66 5e-10
AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein. 66 5e-10
AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form ... 65 6e-10
AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form ... 65 6e-10
AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form ... 65 6e-10
AL731551-2|CAI40247.1| 88|Homo sapiens cubilin (intrinsic fact... 65 6e-10
AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein. 65 6e-10
AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein. 65 6e-10
AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein. 65 6e-10
AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein. 65 6e-10
AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein. 65 6e-10
BC101705-1|AAI01706.1| 1272|Homo sapiens attractin protein. 63 3e-09
AL353193-3|CAH70472.1| 1429|Homo sapiens attractin protein. 63 3e-09
AL353193-2|CAH70471.1| 1272|Homo sapiens attractin protein. 63 3e-09
AL132773-2|CAI22616.1| 1429|Homo sapiens attractin protein. 63 3e-09
AL132773-1|CAI22614.1| 1272|Homo sapiens attractin protein. 63 3e-09
AL109805-3|CAI21878.1| 1429|Homo sapiens attractin protein. 63 3e-09
AL109805-2|CAI21876.1| 1272|Homo sapiens attractin protein. 63 3e-09
AF218915-1|AAF72881.1| 1429|Homo sapiens membrane attractin prec... 63 3e-09
AF218910-1|AAF72882.1| 1272|Homo sapiens secreted attractin prec... 63 3e-09
AB208957-1|BAD92194.1| 793|Homo sapiens suppression of tumorige... 63 3e-09
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 63 3e-09
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 63 3e-09
AF106861-1|AAD03057.1| 1272|Homo sapiens attractin-2 protein. 63 3e-09
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 63 3e-09
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 63 3e-09
AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AY038048-1|AAK71497.1| 996|Homo sapiens SEZ6 protein. 61 1e-08
AF502129-1|AAM22213.1| 996|Homo sapiens HSEZ6b protein protein. 61 1e-08
AL121748-9|CAI40256.1| 735|Homo sapiens neuropilin 1 protein. 60 3e-08
BC005826-1|AAH05826.2| 526|Homo sapiens ST14 protein protein. 59 4e-08
U69263-1|AAC51260.2| 956|Homo sapiens matrilin-2 precursor prot... 59 5e-08
M55683-1|AAA63904.1| 340|Homo sapiens cartilage matrix protein ... 59 5e-08
M55682-1|AAB38702.1| 496|Homo sapiens cartilage matrix protein ... 59 5e-08
BC131710-1|AAI31711.1| 480|Homo sapiens MATN1 protein protein. 59 5e-08
AL137857-2|CAI19322.1| 496|Homo sapiens matrilin 1, cartilage m... 59 5e-08
AK075489-1|BAC11648.1| 451|Homo sapiens rase 7. protein. 59 5e-08
AF283256-1|AAG13949.1| 325|Homo sapiens serine protease SNC19 p... 59 5e-08
BC016394-1|AAH16394.1| 715|Homo sapiens MATN2 protein protein. 58 7e-08
BC010444-1|AAH10444.1| 937|Homo sapiens matrilin 2 protein. 58 7e-08
AL833931-1|CAD38787.1| 1016|Homo sapiens hypothetical protein pr... 58 7e-08
X63556-1|CAA45118.1| 3002|Homo sapiens fibrillin protein. 58 1e-07
X62008-1|CAB56534.1| 517|Homo sapiens fibrillin 15 protein. 58 1e-07
L13923-1|AAB02036.1| 2871|Homo sapiens fibrillin protein. 58 1e-07
AB177803-1|BAD16739.1| 2871|Homo sapiens fibrillin 1 protein. 58 1e-07
AB177802-1|BAD16738.1| 1365|Homo sapiens fibrillin 1 protein. 58 1e-07
L13720-1|AAA58494.1| 678|Homo sapiens growth-arrest-specific pr... 57 2e-07
BX072579-3|CAH71174.1| 678|Homo sapiens growth arrest-specific ... 57 2e-07
BC038984-1|AAH38984.1| 678|Homo sapiens growth arrest-specific ... 57 2e-07
AY358895-1|AAQ89254.1| 915|Homo sapiens MATN2 protein. 57 2e-07
AY256843-1|AAO84057.1| 678|Homo sapiens growth arrested-specifi... 57 2e-07
AK126533-1|BAC86580.1| 624|Homo sapiens protein ( Homo sapiens ... 57 2e-07
AL121748-10|CAI40257.1| 169|Homo sapiens neuropilin 1 protein. 56 3e-07
AK127719-1|BAC87098.1| 618|Homo sapiens protein ( Homo sapiens ... 56 4e-07
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 56 5e-07
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 56 5e-07
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 56 5e-07
BC007408-1|AAH07408.1| 770|Homo sapiens low density lipoprotein... 55 9e-07
AL133553-4|CAI17860.1| 240|Homo sapiens protein ( Human DNA seq... 55 9e-07
AK055383-1|BAB70912.1| 475|Homo sapiens protein ( Homo sapiens ... 55 9e-07
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 55 9e-07
AB009462-1|BAA32330.1| 770|Homo sapiens LDL receptor related pr... 55 9e-07
AB208840-1|BAD92077.1| 830|Homo sapiens fibrillin 1 variant pro... 54 1e-06
BC139923-1|AAI39924.1| 467|Homo sapiens Unknown (protein for MG... 54 2e-06
BC139916-1|AAI39917.1| 467|Homo sapiens Unknown (protein for MG... 54 2e-06
BC047716-1|AAH47716.1| 467|Homo sapiens ATRNL1 protein protein. 54 2e-06
BC009383-1|AAH09383.1| 399|Homo sapiens KREMEN2 protein protein. 54 2e-06
BC003533-1|AAH03533.1| 420|Homo sapiens kringle containing tran... 54 2e-06
AY442317-1|AAR14297.1| 1379|Homo sapiens attractin-like protein ... 54 2e-06
AL512304-1|CAH74015.2| 1379|Homo sapiens attractin-like 1 protein. 54 2e-06
AL392087-1|CAI40794.2| 1379|Homo sapiens attractin-like 1 protein. 54 2e-06
AL357059-1|CAH70625.2| 1379|Homo sapiens attractin-like 1 protein. 54 2e-06
AL356100-1|CAI40417.2| 1379|Homo sapiens attractin-like 1 protein. 54 2e-06
AL355530-2|CAI13482.1| 476|Homo sapiens attractin-like 1 protein. 54 2e-06
AL355530-1|CAI13483.2| 1379|Homo sapiens attractin-like 1 protein. 54 2e-06
AK027775-1|BAB55358.1| 537|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AK027669-1|BAB55281.1| 420|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AB086405-1|BAC00872.1| 462|Homo sapiens kringle-containing tran... 54 2e-06
AB086357-1|BAC00825.1| 399|Homo sapiens kringle-containing prot... 54 2e-06
AB086356-1|BAC00824.1| 420|Homo sapiens kringle-containing prot... 54 2e-06
AB086355-1|BAC00823.1| 424|Homo sapiens kringle-containing prot... 54 2e-06
Y00692-1|CAA68687.1| 676|Homo sapiens preproprotein S protein. 53 3e-06
X12892-1|CAA31383.1| 650|Homo sapiens protein ( H.sapiens mRNA ... 53 3e-06
M57853-1|AAA60357.1| 676|Homo sapiens S protein protein. 53 3e-06
M36564-1|AAA60180.1| 650|Homo sapiens PROS1 protein. 53 3e-06
M15036-1|AAA36479.1| 676|Homo sapiens protein ( Human vitamin K... 53 3e-06
M14338-1|AAA60181.1| 650|Homo sapiens protein S precursor protein. 53 3e-06
BC015801-1|AAH15801.1| 676|Homo sapiens PROS1 protein protein. 53 3e-06
AY358493-1|AAQ88857.1| 345|Homo sapiens fallotein (VEGF-E) prot... 53 3e-06
AY308744-1|AAP45054.1| 497|Homo sapiens protein S (alpha) protein. 53 3e-06
AF280548-1|AAG41893.1| 83|Homo sapiens neuropilin-1 protein. 53 3e-06
AF260738-1|AAK51637.1| 345|Homo sapiens platelet-derived growth... 53 3e-06
AF244813-1|AAF80597.1| 345|Homo sapiens platelet-derived growth... 53 3e-06
AF091434-1|AAF00049.1| 345|Homo sapiens secretory growth factor... 53 3e-06
AC092608-1|AAY40906.1| 305|Homo sapiens unknown protein. 53 3e-06
AB033831-1|BAB03266.1| 345|Homo sapiens spinal cord-derived gro... 53 3e-06
X04571-1|CAA28240.1| 1207|Homo sapiens protein ( Human mRNA for ... 53 4e-06
BC113461-1|AAI13462.1| 1207|Homo sapiens epidermal growth factor... 53 4e-06
BC093731-1|AAH93731.1| 1207|Homo sapiens epidermal growth factor... 53 4e-06
BC000567-1|AAH00567.1| 809|Homo sapiens SEZ6L2 protein protein. 53 4e-06
AY506357-1|AAR84237.1| 1152|Homo sapiens truncated epidermal gro... 53 4e-06
AY358404-1|AAQ88770.1| 910|Homo sapiens PSK-1 protein. 53 4e-06
AK074998-1|BAC11345.1| 578|Homo sapiens protein ( Homo sapiens ... 53 4e-06
AJ245822-1|CAB57952.1| 840|Homo sapiens type I transmembrane re... 53 4e-06
AJ245821-1|CAB57951.1| 580|Homo sapiens putative secreted molec... 53 4e-06
AJ245820-1|CAB57950.1| 853|Homo sapiens type I transmembrane re... 53 4e-06
Z85999-2|CAI43171.1| 539|Homo sapiens discoidin, CUB and LCCL d... 52 5e-06
Z85999-1|CAI43170.1| 516|Homo sapiens discoidin, CUB and LCCL d... 52 5e-06
BC035671-1|AAH35671.1| 539|Homo sapiens discoidin, CUB and LCCL... 52 5e-06
AY358347-1|AAQ88713.1| 406|Homo sapiens VPPP1921 protein. 52 5e-06
AL132671-2|CAI43159.1| 539|Homo sapiens discoidin, CUB and LCCL... 52 5e-06
AL132671-1|CAI23376.1| 516|Homo sapiens discoidin, CUB and LCCL... 52 5e-06
AB075863-1|BAB85569.1| 418|Homo sapiens KIAA1983 protein protein. 52 5e-06
AK223422-1|BAD97142.1| 420|Homo sapiens kringle-containing tran... 52 6e-06
AK092010-1|BAC03789.1| 581|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AK075033-1|BAC11365.1| 381|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AF502130-1|AAM22214.1| 510|Homo sapiens HSEZ6b protein isoform ... 52 6e-06
BC077719-1|AAH77719.1| 219|Homo sapiens VWCE protein protein. 52 8e-06
BC052564-1|AAH52564.1| 219|Homo sapiens VWCE protein protein. 52 8e-06
BC042143-1|AAH42143.1| 237|Homo sapiens VWCE protein protein. 52 8e-06
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 52 8e-06
AJ297949-1|CAC17138.1| 37|Homo sapiens MAp19 protein protein. 52 8e-06
Y13622-1|CAA73944.1| 1587|Homo sapiens latent TGF-beta binding p... 51 1e-05
BC141811-1|AAI41812.1| 540|Homo sapiens matrilin 4 protein. 51 1e-05
BC009222-1|AAH09222.1| 99|Homo sapiens NRP2 protein protein. 51 1e-05
AL021578-2|CAI21077.1| 432|Homo sapiens matrilin 4 protein. 51 1e-05
AL021578-1|CAB46380.1| 622|Homo sapiens matrilin 4 protein. 51 1e-05
AK074597-1|BAC11083.1| 540|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AK074595-1|BAC11081.1| 488|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AF051345-1|AAC39880.2| 1624|Homo sapiens latent transforming gro... 51 1e-05
AF051344-1|AAC39879.2| 1557|Homo sapiens latent transforming gro... 51 1e-05
X82494-1|CAA57876.1| 1184|Homo sapiens fibulin-2 protein. 51 1e-05
BC131763-1|AAI31764.1| 581|Homo sapiens matrilin 4 protein. 51 1e-05
BC051690-1|AAH51690.1| 1184|Homo sapiens fibulin 2 protein. 51 1e-05
AY130459-1|AAN05436.1| 1231|Homo sapiens fibulin 2 protein. 51 1e-05
AY130458-1|AAN05435.1| 1231|Homo sapiens fibulin 2 protein. 51 1e-05
AL021578-3|CAB39280.1| 581|Homo sapiens matrilin 4 protein. 51 1e-05
AJ007581-1|CAA07569.1| 581|Homo sapiens matrilin-4 protein. 51 1e-05
BC126440-1|AAI26441.1| 321|Homo sapiens OIT3 protein protein. 50 2e-05
AY358339-1|AAQ88705.1| 545|Homo sapiens PPFL826 protein. 50 2e-05
AY013707-1|AAG40096.2| 545|Homo sapiens LZP protein. 50 2e-05
AK096435-1|BAC04788.1| 545|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AK095973-1|BAC04663.1| 524|Homo sapiens protein ( Homo sapiens ... 50 2e-05
BC031871-1|AAH31871.1| 225|Homo sapiens CSMD2 protein protein. 50 3e-05
AL139140-1|CAI19066.1| 225|Homo sapiens CUB and Sushi multiple ... 50 3e-05
AY358903-1|AAQ89262.1| 273|Homo sapiens VEMF protein. 50 3e-05
AL590226-1|CAH71721.1| 273|Homo sapiens EGF-like-domain, multip... 50 3e-05
AF186111-1|AAF01429.1| 273|Homo sapiens NOTCH4-like protein pro... 50 3e-05
BC088371-1|AAH88371.1| 273|Homo sapiens EGF-like-domain, multip... 49 4e-05
BC012377-1|AAH12377.1| 273|Homo sapiens EGF-like-domain, multip... 49 4e-05
AY358902-1|AAQ89261.1| 273|Homo sapiens VEMF protein. 49 4e-05
AY358901-1|AAQ89260.1| 273|Homo sapiens VEMF protein. 49 4e-05
AB231861-1|BAE19679.1| 1950|Homo sapiens low-density lipoprotein... 49 4e-05
AB125649-1|BAD01469.1| 273|Homo sapiens VE-statin protein. 49 4e-05
AB084910-1|BAD83615.1| 1905|Homo sapiens low density lipoprotein... 49 4e-05
AB011540-1|BAA32468.1| 1576|Homo sapiens MEGF7 protein. 49 4e-05
Z98047-1|CAI19628.1| 703|Homo sapiens fibulin 1 protein. 49 6e-05
Z95331-3|CAI41717.1| 703|Homo sapiens fibulin 1 protein. 49 6e-05
X53743-1|CAA37772.1| 683|Homo sapiens fibulin-1 C protein. 49 6e-05
X53742-1|CAA37771.1| 601|Homo sapiens fibulin-1 B protein. 49 6e-05
X53741-1|CAA37770.1| 566|Homo sapiens fibulin-1 A protein. 49 6e-05
U01244-1|AAB17099.1| 703|Homo sapiens fibulin-1D protein. 49 6e-05
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 49 6e-05
BC022497-1|AAH22497.1| 683|Homo sapiens fibulin 1 protein. 49 6e-05
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 49 6e-05
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 49 6e-05
AL021391-3|CAI18930.1| 703|Homo sapiens fibulin 1 protein. 49 6e-05
AK075566-1|BAC11705.1| 638|Homo sapiens protein ( Homo sapiens ... 49 6e-05
AK074396-1|BAB85069.1| 220|Homo sapiens protein ( Homo sapiens ... 49 6e-05
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 49 6e-05
AF217999-1|AAG17241.1| 495|Homo sapiens unknown protein. 49 6e-05
AF126110-1|AAK37822.1| 703|Homo sapiens fibulin-1 isoform D pre... 49 6e-05
M34057-1|AAA61160.1| 1394|Homo sapiens TGFB1 protein. 48 8e-05
CR457140-1|CAG33421.1| 448|Homo sapiens FBLN5 protein. 48 8e-05
BC130289-1|AAI30290.1| 1395|Homo sapiens latent transforming gro... 48 8e-05
BC022280-1|AAH22280.1| 448|Homo sapiens fibulin 5 protein. 48 8e-05
AJ133490-1|CAB38568.1| 448|Homo sapiens fibulin-5 protein. 48 8e-05
AF489528-1|AAM03124.1| 1394|Homo sapiens transforming growth fac... 48 8e-05
AF112152-1|AAD41768.1| 448|Homo sapiens developmental arteries ... 48 8e-05
AF093118-1|AAC62107.1| 448|Homo sapiens UP50 protein. 48 8e-05
AC019127-1|AAY24260.1| 697|Homo sapiens unknown protein. 48 8e-05
AB208801-1|BAD92038.1| 1348|Homo sapiens latent transforming gro... 48 8e-05
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 48 1e-04
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 48 1e-04
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 48 1e-04
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 48 1e-04
S73849-1|AAB31735.1| 873|Homo sapiens very low density lipoprot... 47 2e-04
L22431-1|AAA61344.1| 873|Homo sapiens very low density lipoprot... 47 2e-04
L20470-1|AAA53684.1| 873|Homo sapiens very low density lipoprot... 47 2e-04
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 47 2e-04
D16532-1|BAA03969.1| 873|Homo sapiens very low density lipoprot... 47 2e-04
D16494-1|BAA03946.1| 845|Homo sapiens very low density lipoprot... 47 2e-04
D16493-1|BAA03945.1| 873|Homo sapiens very low density lipoprot... 47 2e-04
DQ067198-1|AAY46157.1| 873|Homo sapiens very low density lipopr... 47 2e-04
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 47 2e-04
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 47 2e-04
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 47 2e-04
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 47 2e-04
AL450467-4|CAH72455.1| 845|Homo sapiens very low density lipopr... 47 2e-04
AL450467-3|CAH72454.1| 873|Homo sapiens very low density lipopr... 47 2e-04
AL450467-2|CAH72453.1| 752|Homo sapiens very low density lipopr... 47 2e-04
AK092381-1|BAC03874.1| 752|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 47 2e-04
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 47 2e-04
AB208822-1|BAD92059.1| 555|Homo sapiens Very low-density lipopr... 47 2e-04
Z37976-1|CAA86030.1| 1821|Homo sapiens LTBP-2 precursor protein. 47 2e-04
Y13341-1|CAA73785.1| 310|Homo sapiens matrilin-3 precursor prot... 47 2e-04
S82451-1|AAB37459.1| 1821|Homo sapiens latent transforming growt... 47 2e-04
BC139907-1|AAI39908.1| 486|Homo sapiens matrilin 3 protein. 47 2e-04
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 47 2e-04
BC038242-1|AAH38242.1| 261|Homo sapiens Similar to RIKEN cDNA 1... 47 2e-04
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 47 2e-04
AY358898-1|AAQ89257.1| 448|Homo sapiens FBLN5 protein. 47 2e-04
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AJ224741-1|CAA12110.1| 486|Homo sapiens matrilin-3 protein. 47 2e-04
AJ001047-1|CAA04501.1| 303|Homo sapiens Matrilin-3 protein. 47 2e-04
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 47 2e-04
AC079145-2|AAX88937.1| 486|Homo sapiens unknown protein. 47 2e-04
Z95116-2|CAM25375.1| 492|Homo sapiens kringle containing transm... 46 3e-04
Z95116-1|CAI17987.1| 460|Homo sapiens protein ( Human DNA seque... 46 3e-04
BC063787-1|AAH63787.1| 458|Homo sapiens kringle containing tran... 46 3e-04
AL021393-3|CAM25378.1| 492|Homo sapiens kringle containing tran... 46 3e-04
AL021393-2|CAI17991.1| 460|Homo sapiens protein ( Human DNA seq... 46 3e-04
AK056425-1|BAB71180.1| 492|Homo sapiens protein ( Homo sapiens ... 46 3e-04
AB059618-1|BAB40969.1| 473|Homo sapiens kringle-containing tran... 46 3e-04
CR541934-1|CAG46732.1| 443|Homo sapiens EFEMP2 protein. 46 4e-04
BC010456-1|AAH10456.1| 443|Homo sapiens EGF-containing fibulin-... 46 4e-04
AY358899-1|AAQ89258.1| 443|Homo sapiens EFEMP2 protein. 46 4e-04
AJ132819-1|CAA10791.2| 443|Homo sapiens fibulin-4 protein. 46 4e-04
AF124486-1|AAG45245.1| 443|Homo sapiens fibulin-like extracellu... 46 4e-04
AF109121-1|AAF65188.1| 443|Homo sapiens EGF-containing fibulin-... 46 4e-04
AF093119-1|AAC62108.1| 439|Homo sapiens UPH1 protein. 46 4e-04
AB030655-1|BAA92880.1| 443|Homo sapiens mutant p53 binding prot... 46 4e-04
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec... 46 5e-04
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein... 46 5e-04
BC105633-1|AAI05634.1| 757|Homo sapiens tumor endothelial marke... 46 5e-04
BC104484-1|AAI04485.1| 757|Homo sapiens tumor endothelial marke... 46 5e-04
BC051340-1|AAH51340.1| 757|Homo sapiens CD248 molecule, endosia... 46 5e-04
AJ295846-1|CAC34381.1| 757|Homo sapiens endosialin protein prot... 46 5e-04
AF280549-1|AAG41894.1| 107|Homo sapiens neuropilin-1 protein. 46 5e-04
AF279142-1|AAG00867.1| 757|Homo sapiens tumor endothelial marke... 46 5e-04
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re... 46 5e-04
AB209121-1|BAD92358.1| 620|Homo sapiens Mutant p53 binding prot... 46 5e-04
AF283342-1|AAL38107.1| 881|Homo sapiens candidate tumor suppres... 45 7e-04
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 45 7e-04
AC068287-1|AAY24318.1| 223|Homo sapiens unknown protein. 45 7e-04
Z75190-1|CAA99509.1| 699|Homo sapiens apolipoprotein E receptor... 45 0.001
U04441-1|AAB02882.1| 1751|Homo sapiens glycoprotein 330 protein. 45 0.001
D86407-2|BAA21825.1| 793|Homo sapiens ApoER2delta4-7 protein. 45 0.001
D86407-1|BAA21824.1| 963|Homo sapiens ApoER2 protein. 45 0.001
D50678-1|BAA09328.1| 963|Homo sapiens apolipoprotein E receptor... 45 0.001
BC126405-1|AAI26406.1| 1613|Homo sapiens low density lipoprotein... 45 0.001
BC117136-1|AAI17137.1| 1613|Homo sapiens low density lipoprotein... 45 0.001
BC051836-1|AAH51836.2| 904|Homo sapiens low density lipoprotein... 45 0.001
AL606760-4|CAI18908.1| 963|Homo sapiens low density lipoprotein... 45 0.001
AL606760-3|CAI18909.1| 700|Homo sapiens low density lipoprotein... 45 0.001
AL606760-2|CAI18910.1| 904|Homo sapiens low density lipoprotein... 45 0.001
AL355483-3|CAI22782.1| 700|Homo sapiens low density lipoprotein... 45 0.001
AL355483-2|CAI22780.1| 904|Homo sapiens low density lipoprotein... 45 0.001
AL355483-1|CAI22781.1| 963|Homo sapiens low density lipoprotein... 45 0.001
AF074264-1|AAC33006.1| 1613|Homo sapiens LDL receptor-related pr... 45 0.001
AB209683-1|BAD92920.1| 1477|Homo sapiens low density lipoprotein... 45 0.001
BC072015-1|AAH72015.1| 296|Homo sapiens LRP1 protein protein. 44 0.001
BC052593-1|AAH52593.1| 296|Homo sapiens LRP1 protein protein. 44 0.001
BC045107-1|AAH45107.1| 292|Homo sapiens LRP1 protein protein. 44 0.001
BC021204-1|AAH21204.1| 439|Homo sapiens LRP1 protein protein. 44 0.001
AY358336-1|AAQ88702.1| 509|Homo sapiens DFLL295 protein. 44 0.001
U89336-6|AAB47494.1| 293|Homo sapiens NG3 protein. 44 0.002
BX284686-12|CAM26220.1| 293|Homo sapiens EGF-like-domain, multi... 44 0.002
BC052591-1|AAH52591.1| 293|Homo sapiens EGF-like-domain, multip... 44 0.002
BC035574-1|AAH35574.1| 293|Homo sapiens EGF-like-domain, multip... 44 0.002
>BC113577-1|AAI13578.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>BC112366-1|AAI12367.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>BC112341-1|AAI12342.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>AL391136-1|CAH72234.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>AL138765-2|CAI13580.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>AL136181-1|CAH72983.1| 1015|Homo sapiens tolloid-like 2 protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>AF059516-1|AAD42979.1| 1015|Homo sapiens tolloid-like 2 protein
protein.
Length = 1015
Score = 669 bits (1654), Expect = 0.0
Identities = 305/595 (51%), Positives = 402/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 596
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 597 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 656
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 657 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 711
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 712 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 771
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 772 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 831
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 832 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 891
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 892 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 951
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 952 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1006
Score = 147 bits (355), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
>AB023149-1|BAA76776.2| 1078|Homo sapiens KIAA0932 protein protein.
Length = 1078
Score = 669 bits (1652), Expect = 0.0
Identities = 305/595 (51%), Positives = 401/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 482 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 539
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W++ V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 540 SPNYPDDYRPSKECVWRIMVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 599
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG++ P D++S+SN+L + F SD ++ KAGF+A F KE DEC+ DHG C H CVNTL
Sbjct: 600 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPDHGGCEHRCVNTL 659
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CACD GYEL +D K CE ACGG + NGTITSP +P+ YP KNC+W++VAP Q+
Sbjct: 660 GSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQY 719
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+LEGN + C+YD V V S L D + HG FCG+ P +TS + +R
Sbjct: 720 RISLQFEVFELEGNDV----CKYDFVEVRSGLSPDA-KLHGRFCGSETPEVITSQSNNMR 774
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DECA++NGGCQHEC NT G Y C C +G+ LH N HDC
Sbjct: 775 VEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDC 834
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H ++ GT+ SPN+P YP+R++C W S+T GHR+KL FN FE+E HQECAY
Sbjct: 835 KEAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAY 894
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ +YDG + LG FCGSK P +AS + M++ F SD SVQRKGF A HST CGG
Sbjct: 895 DHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVHSTECGG 954
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + K LYSHA++GDN Y S A CDW I A + V+LTF TFE+E EA+C YDY+
Sbjct: 955 RLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYM 1014
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+ + FCG EI S ++L++RFRTDD++ KGF A Y K
Sbjct: 1015 EAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARYTSTK 1069
Score = 146 bits (354), Expect = 2e-34
Identities = 73/229 (31%), Positives = 122/229 (53%), Gaps = 6/229 (2%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 423 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 482
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 483 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 540
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 541 -PNYPDD-YRPSKECVWRIMVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 598
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY--QMVKPTWSD 602
FCG + P ++ S+S L ++F +D S+ GF+A++ ++ + +W D
Sbjct: 599 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 647
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 380 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 439
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 440 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 499
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 500 TDSRLWVEFRSSSNILGKGFFAAY 523
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 410 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 466
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 467 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 523
>U91963-1|AAB93878.1| 1013|Homo sapiens tolloid-like protein protein.
Length = 1013
Score = 667 bits (1649), Expect = 0.0
Identities = 297/595 (49%), Positives = 403/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
+P+LGR CG ++ ST SR+ + ++ +GF A YEA+CGG+I + G ++
Sbjct: 417 SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIR-KNEGQIQ 474
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P K C+WK++V + Y V L F SFE+E HD C+YD ++VRDG S +SPLIG
Sbjct: 475 SPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIG 534
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG+ P DIRSTSN L + F SD TV KAGF+A F KE DECA D G C C+NTL
Sbjct: 535 RFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTL 594
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CAC+ GYEL D + CE ACGG L NGTIT+P +P+ YPP KNC+W++VAP Q+
Sbjct: 595 GSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQY 654
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI++ F F+LEGN + C+YD V + S L ++ + HG FCG +P +TS + +R
Sbjct: 655 RISVKFEFFELEGNEV----CKYDYVEIWSGLSSES-KLHGKFCGAEVPEVITSQFNNMR 709
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
++F SD +V + GF A ++ D DEC+++NGGCQHEC NT+G Y C C +GF LH NKHDC
Sbjct: 710 IEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDC 769
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE C+ + P G I SPN+P YP+RK+C W+ S TPGHRIKL F+ FE+E HQECAY
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ ++DG + LG CG+K+P ++A+ N+M++ F SD SVQRKGF ATHST CGG
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGG 889
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + + LYSHA++GDN Y + DC+W + + R ++L+F TFE+E EA+C YDYV
Sbjct: 890 RLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYV 949
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++F FCG P EI S +++L+ F TDD++ KGF Y+ ++
Sbjct: 950 ELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIR 1004
Score = 151 bits (366), Expect = 7e-36
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 4/227 (1%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + +G + SP +P YP+ C+W+ S TPG +I L F +L C YD++
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG LG FCG KLP ++ ++ ++M++ F+S + KGF A + CGG +
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRK 468
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
E Y D+ Y +C W I ++ V LTF +FE+ER NC YDY++V
Sbjct: 469 NE---GQIQSPNYPDD-YRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRD 524
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FCG P +I STS L ++F +D ++ GF+A++
Sbjct: 525 GTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571
Score = 91.9 bits (218), Expect = 6e-18
Identities = 42/118 (35%), Positives = 65/118 (55%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y G+ +SNG+L SP +P+ Y CIW++SV ++ L F + ++
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSS 400
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD ++VRDG SPL+G FCG K+P + ST +++ + F S S GF+A +
Sbjct: 401 LCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Score = 77.8 bits (183), Expect = 1e-13
Identities = 48/132 (36%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L NG ++SP FP YP +C+W + P +I LNFT DL + + C
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL----CW 403
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YID 323
YD + V G FCG LP +TS S + ++F S + GFAAVY I
Sbjct: 404 YDYIEVRDGYWRK-SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAIC 462
Query: 324 VDECAENNGGCQ 335
E +N G Q
Sbjct: 463 GGEIRKNEGQIQ 474
>AF282732-1|AAF86287.1| 1013|Homo sapiens tolloid-like protein
protein.
Length = 1013
Score = 667 bits (1649), Expect = 0.0
Identities = 297/595 (49%), Positives = 403/595 (67%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
+P+LGR CG ++ ST SR+ + ++ +GF A YEA+CGG+I + G ++
Sbjct: 417 SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVG-KGFAAVYEAICGGEIR-KNEGQIQ 474
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P K C+WK++V + Y V L F SFE+E HD C+YD ++VRDG S +SPLIG
Sbjct: 475 SPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENSPLIG 534
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
FCG+ P DIRSTSN L + F SD TV KAGF+A F KE DECA D G C C+NTL
Sbjct: 535 RFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPDRGGCEQRCLNTL 594
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+CAC+ GYEL D + CE ACGG L NGTIT+P +P+ YPP KNC+W++VAP Q+
Sbjct: 595 GSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQY 654
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI++ F F+LEGN + C+YD V + S L ++ + HG FCG +P +TS + +R
Sbjct: 655 RISVKFEFFELEGNEV----CKYDYVEIWSGLSSES-KLHGKFCGAEVPEVITSQFNNMR 709
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
++F SD +V + GF A ++ D DEC+++NGGCQHEC NT+G Y C C +GF LH NKHDC
Sbjct: 710 IEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDC 769
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE C+ + P G I SPN+P YP+RK+C W+ S TPGHRIKL F+ FE+E HQECAY
Sbjct: 770 KEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAY 829
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ ++DG + LG CG+K+P ++A+ N+M++ F SD SVQRKGF ATHST CGG
Sbjct: 830 DHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATHSTECGG 889
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L A + + LYSHA++GDN Y + DC+W + + R ++L+F TFE+E EA+C YDYV
Sbjct: 890 RLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADCGYDYV 949
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++F FCG P EI S +++L+ F TDD++ KGF Y+ ++
Sbjct: 950 ELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYKSIR 1004
Score = 151 bits (366), Expect = 7e-36
Identities = 75/227 (33%), Positives = 116/227 (51%), Gaps = 4/227 (1%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + +G + SP +P YP+ C+W+ S TPG +I L F +L C YD++
Sbjct: 349 CGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIE 408
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG LG FCG KLP ++ ++ ++M++ F+S + KGF A + CGG +
Sbjct: 409 VRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIRK 468
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
E Y D+ Y +C W I ++ V LTF +FE+ER NC YDY++V
Sbjct: 469 NE---GQIQSPNYPDD-YRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRD 524
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FCG P +I STS L ++F +D ++ GF+A++
Sbjct: 525 GTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571
Score = 91.9 bits (218), Expect = 6e-18
Identities = 42/118 (35%), Positives = 65/118 (55%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y G+ +SNG+L SP +P+ Y CIW++SV ++ L F + ++
Sbjct: 341 RKLYRCPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSS 400
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD ++VRDG SPL+G FCG K+P + ST +++ + F S S GF+A +
Sbjct: 401 LCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVY 458
Score = 77.8 bits (183), Expect = 1e-13
Identities = 48/132 (36%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L NG ++SP FP YP +C+W + P +I LNFT DL + + C
Sbjct: 348 ACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSL----CW 403
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YID 323
YD + V G FCG LP +TS S + ++F S + GFAAVY I
Sbjct: 404 YDYIEVRDGYWRK-SPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAIC 462
Query: 324 VDECAENNGGCQ 335
E +N G Q
Sbjct: 463 GGEIRKNEGQIQ 474
>U50330-1|AAA93462.1| 986|Homo sapiens procollagen C-proteinase
protein.
Length = 986
Score = 653 bits (1614), Expect = 0.0
Identities = 294/595 (49%), Positives = 398/595 (66%), Gaps = 8/595 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+ GR CGS + ST SRL V ++ +GF A YEA+CGGD++ D GH++
Sbjct: 390 APLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY-GHIQ 447
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K+CIW++ V + + V L F SFE+E HD+C+YD ++VRDG S S LIG
Sbjct: 448 SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIG 507
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG-CSHSCVNTL 182
+CG++ P DI+STS++L + F SD ++ KAGF+ F KE DEC+ + G C C+NTL
Sbjct: 508 RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTL 567
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+C+CD GYEL D ++CE ACGG L NG+ITSP +P+ YPP KNC+W++VAP Q+
Sbjct: 568 GSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQY 627
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+ EGN + C+YD V V S L AD + HG FCG+ P +TS + +R
Sbjct: 628 RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVITSQYNNMR 682
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
V+F SD +V + GF A ++ D DEC+++NGGCQ +C NT G YEC C SGF LH NKHDC
Sbjct: 683 VEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDC 742
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
KE GC H VT GTI SPN+P YP++K+C W S+TPGHR+KL F ++E ECAY
Sbjct: 743 KEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAY 802
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
DH+ ++DG A LG FCGSK P V+A+ ++M++ F SD SVQRKGF A+H+T CGG
Sbjct: 803 DHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGG 862
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ A + K LYSHA++GDN Y DC+W I A + V+L F TFE+E E +C YDY+
Sbjct: 863 QVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYM 922
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++F +CG P E+ S +++LV+F +DD++ KGF Y K
Sbjct: 923 ELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK 977
Score = 147 bits (356), Expect = 1e-34
Identities = 75/218 (34%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G SP YP Y A CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
G FCGSKLP ++++ +++++ F+S + KGF A + CGG ++ H+ S
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG--DVKKDYGHIQS 448
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y C W I+ V LTF +FE+ER +C YDY++V
Sbjct: 449 -PNYPDD-YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLI 506
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + P +I STS L ++F +D S+ GF+ ++
Sbjct: 507 GRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/118 (38%), Positives = 63/118 (53%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y+ G+ DS G+ SP YP+ Y + C+W++SV ++ L F S ++
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR 373
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD V+VRDG +PL G FCG K+P I ST ++L V F S S GF A +
Sbjct: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 76.6 bits (180), Expect = 3e-13
Identities = 46/120 (38%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G +SP +P Y +C+W I P +I LNFT DL + +
Sbjct: 318 KCP-ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL-- 374
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V R G FCG+ LP P+ S S L V+F S + GF AVY
Sbjct: 375 --CWYDYVEVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
>M22488-1|AAA51833.1| 730|Homo sapiens BMP1 protein.
Length = 730
Score = 339 bits (833), Expect = 2e-92
Identities = 160/335 (47%), Positives = 223/335 (66%), Gaps = 8/335 (2%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+ GR CGS + ST SRL V ++ +GF A YEA+CGGD++ D GH++
Sbjct: 390 APLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY-GHIQ 447
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K+CIW++ V + + V L F SFE+E HD+C+YD ++VRDG S S LIG
Sbjct: 448 SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIG 507
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH-GCSHSCVNTL 182
+CG++ P DI+STS++L + F SD ++ KAGF+ F KE DEC+ + GC C+NTL
Sbjct: 508 RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTL 567
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+C+CD GYEL D ++CE ACGG L NG+ITSP +P+ YPP KNC+W++VAP Q+
Sbjct: 568 GSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQY 627
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+ EGN + C+YD V V S L AD + HG FCG+ P +TS + +R
Sbjct: 628 RISLQFDFFETEGNDV----CKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMR 682
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHE 337
V+F SD +V + GF A ++ + + G H+
Sbjct: 683 VEFKSDNTVSKKGFKAHFFSEKRPALQPPRGRPHQ 717
Score = 211 bits (515), Expect = 7e-54
Identities = 105/273 (38%), Positives = 152/273 (55%), Gaps = 7/273 (2%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
E CGG + G I SP++P+ Y P K C+W I + L F F++E +
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH----DS 487
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + V ++ G +CG P + S S L ++F SDGS++++GFA ++
Sbjct: 488 CAYDYLEVRDG-HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 323 DVDECAE-NNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSP 381
+VDEC+ N GGC+ C NTLG Y+C+C G+ L P+K C E C +T +G+I SP
Sbjct: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRC-EAACGGFLTKLNGSITSP 605
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
+P YP K+C+WQ +RI L F+ FE E + C YD V + G +AD K G F
Sbjct: 606 GWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKF 665
Query: 442 CGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
CGS+ P ++ + N M + FKSD +V +KGF A
Sbjct: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 698
Score = 147 bits (356), Expect = 1e-34
Identities = 75/218 (34%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G SP YP Y A CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
G FCGSKLP ++++ +++++ F+S + KGF A + CGG ++ H+ S
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG--DVKKDYGHIQS 448
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y C W I+ V LTF +FE+ER +C YDY++V
Sbjct: 449 -PNYPDD-YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLI 506
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + P +I STS L ++F +D S+ GF+ ++
Sbjct: 507 GRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/118 (38%), Positives = 63/118 (53%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y+ G+ DS G+ SP YP+ Y + C+W++SV ++ L F S ++
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR 373
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD V+VRDG +PL G FCG K+P I ST ++L V F S S GF A +
Sbjct: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 76.6 bits (180), Expect = 3e-13
Identities = 46/120 (38%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G +SP +P Y +C+W I P +I LNFT DL + +
Sbjct: 318 KCP-ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL-- 374
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V R G FCG+ LP P+ S S L V+F S + GF AVY
Sbjct: 375 --CWYDYVEVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 66.5 bits (155), Expect = 3e-10
Identities = 34/95 (35%), Positives = 44/95 (46%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W I + L F + +L R C YDYV+V FCG
Sbjct: 340 NGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGS 399
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
K+P IVST L V FR+ + V KGF A Y+ +
Sbjct: 400 KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 59.7 bits (138), Expect = 3e-08
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG+L+ ++ + + Y +C W + AP + + L F FE E C+
Sbjct: 590 ACGGFLT---KLNGSITSPGW-PKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YD+V+V FCG + P I S + V F++D+++ KGF A +
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>AB209590-1|BAD92827.1| 803|Homo sapiens bone morphogenetic protein
1 isoform 1, precursor variant protein.
Length = 803
Score = 339 bits (833), Expect = 2e-92
Identities = 160/335 (47%), Positives = 223/335 (66%), Gaps = 8/335 (2%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+ GR CGS + ST SRL V ++ +GF A YEA+CGGD++ D GH++
Sbjct: 463 APLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY-GHIQ 520
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K+CIW++ V + + V L F SFE+E HD+C+YD ++VRDG S S LIG
Sbjct: 521 SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIG 580
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH-GCSHSCVNTL 182
+CG++ P DI+STS++L + F SD ++ KAGF+ F KE DEC+ + GC C+NTL
Sbjct: 581 RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTL 640
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+C+CD GYEL D ++CE ACGG L NG+ITSP +P+ YPP KNC+W++VAP Q+
Sbjct: 641 GSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQY 700
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+ EGN + C+YD V V S L AD + HG FCG+ P +TS + +R
Sbjct: 701 RISLQFDFFETEGNDV----CKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMR 755
Query: 303 VQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHE 337
V+F SD +V + GF A ++ + + G H+
Sbjct: 756 VEFKSDNTVSKKGFKAHFFSEKRPALQPPRGRPHQ 790
Score = 211 bits (515), Expect = 7e-54
Identities = 105/273 (38%), Positives = 152/273 (55%), Gaps = 7/273 (2%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
E CGG + G I SP++P+ Y P K C+W I + L F F++E +
Sbjct: 505 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH----DS 560
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + V ++ G +CG P + S S L ++F SDGS++++GFA ++
Sbjct: 561 CAYDYLEVRDG-HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 619
Query: 323 DVDECAE-NNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSP 381
+VDEC+ N GGC+ C NTLG Y+C+C G+ L P+K C E C +T +G+I SP
Sbjct: 620 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRC-EAACGGFLTKLNGSITSP 678
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
+P YP K+C+WQ +RI L F+ FE E + C YD V + G +AD K G F
Sbjct: 679 GWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKF 738
Query: 442 CGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
CGS+ P ++ + N M + FKSD +V +KGF A
Sbjct: 739 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 771
Score = 147 bits (356), Expect = 1e-34
Identities = 75/218 (34%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G SP YP Y A CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 404 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 463
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
G FCGSKLP ++++ +++++ F+S + KGF A + CGG ++ H+ S
Sbjct: 464 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG--DVKKDYGHIQS 521
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y C W I+ V LTF +FE+ER +C YDY++V
Sbjct: 522 -PNYPDD-YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLI 579
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + P +I STS L ++F +D S+ GF+ ++
Sbjct: 580 GRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 617
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/118 (38%), Positives = 63/118 (53%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y+ G+ DS G+ SP YP+ Y + C+W++SV ++ L F S ++
Sbjct: 387 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR 446
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD V+VRDG +PL G FCG K+P I ST ++L V F S S GF A +
Sbjct: 447 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 504
Score = 76.6 bits (180), Expect = 3e-13
Identities = 46/120 (38%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G +SP +P Y +C+W I P +I LNFT DL + +
Sbjct: 391 KCP-ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL-- 447
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V R G FCG+ LP P+ S S L V+F S + GF AVY
Sbjct: 448 --CWYDYVEVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 504
Score = 66.5 bits (155), Expect = 3e-10
Identities = 34/95 (35%), Positives = 44/95 (46%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W I + L F + +L R C YDYV+V FCG
Sbjct: 413 NGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGS 472
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
K+P IVST L V FR+ + V KGF A Y+ +
Sbjct: 473 KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 507
Score = 59.7 bits (138), Expect = 3e-08
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG+L+ ++ + + Y +C W + AP + + L F FE E C+
Sbjct: 663 ACGGFLT---KLNGSITSPGW-PKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 718
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YD+V+V FCG + P I S + V F++D+++ KGF A +
Sbjct: 719 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 773
>Y08725-1|CAA69975.1| 717|Homo sapiens BMP1-6 protein.
Length = 717
Score = 338 bits (831), Expect = 3e-92
Identities = 158/319 (49%), Positives = 218/319 (68%), Gaps = 8/319 (2%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+ GR CGS + ST SRL V ++ +GF A YEA+CGGD++ D GH++
Sbjct: 390 APLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY-GHIQ 447
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K+CIW++ V + + V L F SFE+E HD+C+YD ++VRDG S S LIG
Sbjct: 448 SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIG 507
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH-GCSHSCVNTL 182
+CG++ P DI+STS++L + F SD ++ KAGF+ F KE DEC+ + GC C+NTL
Sbjct: 508 RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTL 567
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G Y+C+CD GYEL D ++CE ACGG L NG+ITSP +P+ YPP KNC+W++VAP Q+
Sbjct: 568 GSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQY 627
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
RI+L F F+ EGN + C+YD V V S L AD + HG FCG+ P +TS + +R
Sbjct: 628 RISLQFDFFETEGNDV----CKYDFVEVRSGLTAD-SKLHGKFCGSEKPEVITSQYNNMR 682
Query: 303 VQFTSDGSVHRSGFAAVYY 321
V+F SD +V + GF A ++
Sbjct: 683 VEFKSDNTVSKKGFKAHFF 701
Score = 211 bits (515), Expect = 7e-54
Identities = 105/273 (38%), Positives = 152/273 (55%), Gaps = 7/273 (2%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
E CGG + G I SP++P+ Y P K C+W I + L F F++E +
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH----DS 487
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + V ++ G +CG P + S S L ++F SDGS++++GFA ++
Sbjct: 488 CAYDYLEVRDG-HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 323 DVDECAE-NNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSP 381
+VDEC+ N GGC+ C NTLG Y+C+C G+ L P+K C E C +T +G+I SP
Sbjct: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRC-EAACGGFLTKLNGSITSP 605
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
+P YP K+C+WQ +RI L F+ FE E + C YD V + G +AD K G F
Sbjct: 606 GWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKF 665
Query: 442 CGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
CGS+ P ++ + N M + FKSD +V +KGF A
Sbjct: 666 CGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 698
Score = 147 bits (356), Expect = 1e-34
Identities = 75/218 (34%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G SP YP Y A CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
G FCGSKLP ++++ +++++ F+S + KGF A + CGG ++ H+ S
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG--DVKKDYGHIQS 448
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y C W I+ V LTF +FE+ER +C YDY++V
Sbjct: 449 -PNYPDD-YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLI 506
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + P +I STS L ++F +D S+ GF+ ++
Sbjct: 507 GRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/118 (38%), Positives = 63/118 (53%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y+ G+ DS G+ SP YP+ Y + C+W++SV ++ L F S ++
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR 373
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD V+VRDG +PL G FCG K+P I ST ++L V F S S GF A +
Sbjct: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 76.6 bits (180), Expect = 3e-13
Identities = 46/120 (38%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G +SP +P Y +C+W I P +I LNFT DL + +
Sbjct: 318 KCP-ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL-- 374
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V R G FCG+ LP P+ S S L V+F S + GF AVY
Sbjct: 375 --CWYDYVEVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 66.5 bits (155), Expect = 3e-10
Identities = 34/95 (35%), Positives = 44/95 (46%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W I + L F + +L R C YDYV+V FCG
Sbjct: 340 NGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGS 399
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
K+P IVST L V FR+ + V KGF A Y+ +
Sbjct: 400 KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 59.7 bits (138), Expect = 3e-08
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG+L+ ++ + + Y +C W + AP + + L F FE E C+
Sbjct: 590 ACGGFLT---KLNGSITSPGW-PKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YD+V+V FCG + P I S + V F++D+++ KGF A +
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700
>L35279-1|AAC41710.1| 284|Homo sapiens bone morphogenetic protein
protein.
Length = 284
Score = 320 bits (787), Expect = 7e-87
Identities = 136/275 (49%), Positives = 180/275 (65%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPN 382
D DEC+++NGGCQ +C NT G YEC C SGF LH NKHDCKE GC H VT GTI SPN
Sbjct: 1 DKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCNHKVTSTSGTITSPN 60
Query: 383 YPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFC 442
+P YP++K+C W S+TPGHR+KL F ++E ECAYDH+ ++DG A LG FC
Sbjct: 61 WPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFC 120
Query: 443 GSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDN 502
GSK P V+A+ ++M++ F SD SVQRKGF A+H+T CGG + A + K LYSHA++GDN
Sbjct: 121 GSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDN 180
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIK 562
Y DC+W I A + V+L F TFE+E E +C YDY+++F +CG
Sbjct: 181 NYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPSLGRYCGSG 240
Query: 563 MPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
P E+ S +++LV+F +DD++ KGF Y K
Sbjct: 241 PPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTK 275
Score = 130 bits (313), Expect = 2e-29
Identities = 65/155 (41%), Positives = 84/155 (54%), Gaps = 6/155 (3%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENA-CGGALYGPNGTITSPSFP 223
DEC+ + GC CVNT G YEC C G+ LH + C+ A C + +GTITSP++P
Sbjct: 3 DECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCNHKVTSTSGTITSPNWP 62
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ YP K C W I + P HR+ L F D+E Q EC YD + V A G
Sbjct: 63 DKYPSKKECTWAISSTPGHRVKLTFMEMDIES----QPECAYDHLEVFDGRDAKA-PVLG 117
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAA 318
FCG+ P PV + GS + ++F SD SV R GF A
Sbjct: 118 RFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA 152
Score = 100 bits (239), Expect = 2e-20
Identities = 53/156 (33%), Positives = 82/156 (52%), Gaps = 4/156 (2%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVD--SNGH 61
APVLGR CGS K + +TGSR+ + + ++ +GF+A + CGG + D +
Sbjct: 113 APVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQ-RKGFQASHATECGGQVRADVKTKDL 171
Query: 62 LESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ D+ P + C W + + Y V L F +FEVE C YD +++ DG +P
Sbjct: 172 YSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAP 231
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG P ++ S + +LV F SD T+ K GF
Sbjct: 232 SLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGF 267
Score = 93.1 bits (221), Expect = 3e-18
Identities = 41/117 (35%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA C + ++G + SPN+PD Y K C W +S ++V L F ++E+ C+Y
Sbjct: 42 EAGCNHKV-TSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAY 100
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D ++V DG +P++G FCG K P + +T +++ + F SD++VQ+ GF A+ E
Sbjct: 101 DHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATE 157
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/95 (29%), Positives = 45/95 (47%), Gaps = 5/95 (5%)
Query: 226 YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAF 285
YP +C W IVA + + L F F++E + +C YD + + + G +
Sbjct: 182 YPGGVDCEWVIVAEEGYGVELVFQTFEVEE----ETDCGYDYMELFDGYDSTAPSL-GRY 236
Query: 286 CGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
CG+ P V S G + V+F SD ++ + GF Y
Sbjct: 237 CGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 271
>Y08724-1|CAA69974.1| 622|Homo sapiens BMP1-5 protein.
Length = 622
Score = 225 bits (549), Expect = 5e-58
Identities = 101/201 (50%), Positives = 140/201 (69%), Gaps = 3/201 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+ GR CGS + ST SRL V ++ +GF A YEA+CGGD++ D GH++
Sbjct: 390 APLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVG-KGFFAVYEAICGGDVKKDY-GHIQ 447
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K+CIW++ V + + V L F SFE+E HD+C+YD ++VRDG S S LIG
Sbjct: 448 SPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIG 507
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH-GCSHSCVNTL 182
+CG++ P DI+STS++L + F SD ++ KAGF+ F KE DEC+ + GC C+NTL
Sbjct: 508 RYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTL 567
Query: 183 GGYECACDIGYELHSDGKKCE 203
G Y+C+CD GYEL D ++CE
Sbjct: 568 GSYKCSCDPGYELAPDKRRCE 588
Score = 147 bits (356), Expect = 1e-34
Identities = 75/218 (34%), Positives = 113/218 (51%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G SP YP Y A CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
G FCGSKLP ++++ +++++ F+S + KGF A + CGG ++ H+ S
Sbjct: 391 PLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG--DVKKDYGHIQS 448
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y C W I+ V LTF +FE+ER +C YDY++V
Sbjct: 449 -PNYPDD-YRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLI 506
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + P +I STS L ++F +D S+ GF+ ++
Sbjct: 507 GRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Score = 121 bits (291), Expect = 9e-27
Identities = 61/166 (36%), Positives = 91/166 (54%), Gaps = 8/166 (4%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
E CGG + G I SP++P+ Y P K C+W I + L F F++E +
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH----DS 487
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + V ++ G +CG P + S S L ++F SDGS++++GFA ++
Sbjct: 488 CAYDYLEVRDG-HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFK 546
Query: 323 DVDECAE-NNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGC 367
+VDEC+ N GGC+ C NTLG Y+C+C G+ L P+K C+ GC
Sbjct: 547 EVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCE--GC 590
Score = 93.5 bits (222), Expect = 2e-18
Identities = 40/109 (36%), Positives = 62/109 (56%)
Query: 364 EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
E C DV +G I SPNYP Y K C+W+ + G + L F FE+E H CAYD
Sbjct: 432 EAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
++ + DG S +G +CG + P + ++ +++++ F SDGS+ + GF
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF 540
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/118 (38%), Positives = 63/118 (53%)
Query: 43 RAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD 102
R Y+ G+ DS G+ SP YP+ Y + C+W++SV ++ L F S ++
Sbjct: 314 RKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSR 373
Query: 103 TCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
C YD V+VRDG +PL G FCG K+P I ST ++L V F S S GF A +
Sbjct: 374 LCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 76.6 bits (180), Expect = 3e-13
Identities = 46/120 (38%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G +SP +P Y +C+W I P +I LNFT DL + +
Sbjct: 318 KCP-ACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRL-- 374
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V R G FCG+ LP P+ S S L V+F S + GF AVY
Sbjct: 375 --CWYDYVEVRDGFWRKAPLR-GRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVY 431
Score = 66.5 bits (155), Expect = 3e-10
Identities = 34/95 (35%), Positives = 44/95 (46%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W I + L F + +L R C YDYV+V FCG
Sbjct: 340 NGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGS 399
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
K+P IVST L V FR+ + V KGF A Y+ +
Sbjct: 400 KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
>BC013871-1|AAH13871.1| 593|Homo sapiens TLL2 protein protein.
Length = 593
Score = 170 bits (414), Expect = 1e-41
Identities = 76/159 (47%), Positives = 112/159 (70%), Gaps = 2/159 (1%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
AP+LGR CG + ST SRL V ++ + +GF A YEA CGGD+ D+ G ++
Sbjct: 419 APLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILG-KGFFAAYEATCGGDMNKDA-GQIQ 476
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
SPNYPDDY+P+K C+W+++V + + V L F +FE+E HD+C+YD ++VRDG + +S LIG
Sbjct: 477 SPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALIG 536
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG++ P D++S+SN+L + F SD ++ KAGF+A F K
Sbjct: 537 HFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK 575
Score = 146 bits (353), Expect = 3e-34
Identities = 71/218 (32%), Positives = 116/218 (53%), Gaps = 4/218 (1%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G +P +P YP+ CVW+ S TPG +I L F +L + C YD+V + DG
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYS 495
LG FCG K+P ++++ +++++ F+S ++ KGF A + CGG ++ ++ + S
Sbjct: 420 PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEATCGGDMN--KDAGQIQS 477
Query: 496 HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXX 555
Y D+ Y +C W I V LTF FE+ER +C YDY++V
Sbjct: 478 -PNYPDD-YRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEESALI 535
Query: 556 XTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FCG + P ++ S+S L ++F +D S+ GF+A++
Sbjct: 536 GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
Score = 103 bits (247), Expect = 2e-21
Identities = 45/111 (40%), Positives = 65/111 (58%)
Query: 364 EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
E C D+ G I SPNYP Y K+CVW+ + + G + L F FE+E H CAYD
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
++ + DG + + +G FCG + P V +S N+++M F SDGS+ + GF A
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAA 571
Score = 90.6 bits (215), Expect = 1e-17
Identities = 47/144 (32%), Positives = 71/144 (49%)
Query: 17 PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL 76
P G R T+ + L R Y+ G+ D+ G+ +P +P+ Y
Sbjct: 317 PRQDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDTTGNFSAPGFPNGYPSYSH 376
Query: 77 CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRS 136
C+W++SV ++ L F S ++ C YD V+VRDG +PL+G FCG KIP + S
Sbjct: 377 CVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVS 436
Query: 137 TSNKLLVIFESDSTVQKAGFSATF 160
T ++L V F S S + GF A +
Sbjct: 437 TDSRLWVEFRSSSNILGKGFFAAY 460
Score = 76.2 bits (179), Expect = 3e-13
Identities = 44/120 (36%), Positives = 56/120 (46%), Gaps = 6/120 (5%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KC ACG L G ++P FP YP +C+W I P +I LNFT DL + +
Sbjct: 347 KCP-ACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRL-- 403
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YD V V G FCG +P P+ S S L V+F S ++ GF A Y
Sbjct: 404 --CWYDYVEVRDGYWRKA-PLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAY 460
Score = 74.1 bits (174), Expect = 1e-12
Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 5/119 (4%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
E CGG + G I SP++P+ Y P K C+W I + L F F++E +
Sbjct: 461 EATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERH----DS 516
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YD + V + G FCG P V S + L ++F SDGS++++GFAA ++
Sbjct: 517 CAYDYLEVRDG-PTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF 574
Score = 65.3 bits (152), Expect = 6e-10
Identities = 32/93 (34%), Positives = 46/93 (49%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y S + C W I + L F + +L + C YDYV+V FCG
Sbjct: 369 NGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGD 428
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
K+P +VST L V FR+ +++ KGF A+Y+
Sbjct: 429 KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
>AY210418-1|AAO34701.1| 3487|Homo sapiens CUB and sushi multiple
domains 2 protein.
Length = 3487
Score = 164 bits (399), Expect = 7e-40
Identities = 144/479 (30%), Positives = 218/479 (45%), Gaps = 66/479 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGGD+ S G + SPNYP+ Y P K C WK++V DY +AL F+ F +E YD
Sbjct: 1443 APCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYD 1497
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE-FDE 166
+ + DG SPLIG F G ++P I S+SN L + F SD++V AGF + + +
Sbjct: 1498 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 1557
Query: 167 C---ASIDHGCSHSCVNTLG-GYECACDIGYE----------LHSDGKK--------CEN 204
C SI +G LG C GYE L DGK C
Sbjct: 1558 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 1617
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG G +G + SP++P+ Y + CL+ + P + + F F N + +
Sbjct: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVE---V 1674
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--- 321
+D + HS+L + + G+ G +L P+ + VL ++F++ G GF VY
Sbjct: 1675 HDGHSQHSRLLSSL---SGSHTGESL--PLATSNQVL-IKFSAKGLAPARGFHFVYQAVP 1728
Query: 322 -IDVDECA---ENNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DC--KEGG------- 366
+C+ E G + ++G C+SG+ L + +C G
Sbjct: 1729 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 1788
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++T GTI SP +P Y +CVW+ G I++ F E +
Sbjct: 1789 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 1846
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DGA V LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 1847 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
Score = 157 bits (380), Expect = 1e-37
Identities = 137/475 (28%), Positives = 205/475 (43%), Gaps = 73/475 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA CGG + S G + SP +P Y+ C W + Y + + F F+ E +Y
Sbjct: 749 EAPCGGHLTSPS-GTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTE----VNY 803
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFS---ATFMKE 163
D ++VRDG + +PLIG++ G ++P + STSN L ++F +D + GF T +
Sbjct: 804 DTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ 863
Query: 164 FDECASID---HGCSHSCVNTLGG-YECACDIGYELHSDGK---------------KCEN 204
D C +G H +G +CD GY L SDG+ CE
Sbjct: 864 SDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL-SDGEPLECEPNFQWSRALPSCEA 922
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +GTI SP FP+ YP NC W I + F F LE H Y E
Sbjct: 923 LCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITE 982
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTS---DGSVLRVQFTSDGSVHRSGFAAVY- 320
S T LR+ G+ LP P+++ +V+F SD S+ GF +
Sbjct: 983 NGSFT-------QPLRQ---LTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1032
Query: 321 YIDVDECAEN-------NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGG------- 366
D++ C E G Q +TL +C G+ L GG
Sbjct: 1033 EYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSS 1089
Query: 367 --------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
C + VT GT+ SPN+P Y +C++ T PG I+L FEL
Sbjct: 1090 PLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG- 1148
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGF 472
D + +YDG + + LG+F S++ + + ++ + +++ F +D KGF
Sbjct: 1149 ----DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGF 1199
Score = 153 bits (371), Expect = 2e-36
Identities = 134/477 (28%), Positives = 210/477 (44%), Gaps = 68/477 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG + + G L SPN+P +Y N CI+ + + L+ +FE+ D
Sbjct: 1096 AECGNSV-TGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDV---- 1150
Query: 108 KVKVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+KV DG++ + L+G+F + + STS+ L + F +D+ GF F E
Sbjct: 1151 -LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELI 1209
Query: 166 ECASIDHGCSHSCVNTLGGY-----ECACDIGYELHSD-------GKK---------CEN 204
+C V+ G + +CD GY L G++ C
Sbjct: 1210 KCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1269
Query: 205 ACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG + G +G + SP +P Y NC+W I A I L+F FD E H
Sbjct: 1270 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH------ 1323
Query: 264 EYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D + + + + VL + G ALP + S + + +QF++D + GFA + +
Sbjct: 1324 --DVLRIWDGPVESGVLLKE--LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSV 1379
Query: 323 DVDECAENNGGCQH----------------EC---HNTLGGYECAC---HSGFTLHPNKH 360
+ G Q+ +C + G E +C + F P+
Sbjct: 1380 STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPP 1439
Query: 361 DCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C C D+T P G I SPNYP YP K+C W+ + +P + I L+FN+F LEP
Sbjct: 1440 TCI-APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP---- 1494
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + IYDG + +G F GS+LP + +S N +++ F+SD SV GF+ ++
Sbjct: 1495 GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
Score = 147 bits (356), Expect = 1e-34
Identities = 135/473 (28%), Positives = 201/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG V S+G + SPNYP +Y ++C++ ++VP+DY V +F F T D
Sbjct: 1617 APCGGQY-VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALND 1670
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIR-STSNKLLVIFESDSTVQKAGFSATFMK---- 162
V+V DG S S L+ G + +TSN++L+ F + GF +
Sbjct: 1671 VVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 1730
Query: 163 EFDECASID---HGCSHSCVNTLGGY-ECACDIGYELHSDGK------------------ 200
+C+S+ +G ++G C+ GY L +
Sbjct: 1731 SATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 1790
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGG L GTI SP FPE Y NC+W+IV P I + F E N
Sbjct: 1791 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN---- 1846
Query: 261 QECEYDSVTVHSKLGAD-VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ V GAD + G+F GT +P + S + L + F SD SV +GF
Sbjct: 1847 ----WDSLEVFD--GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE 1900
Query: 320 Y-YIDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEG-------- 365
Y + + C E +NG E + C G+ L + H C G
Sbjct: 1901 YKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 1960
Query: 366 ------GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C V G I SP +P YP+ DC W+ + G + F F EP+
Sbjct: 1961 PPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN-- 2018
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ I +G + +G F GS+LP ++++ ++ + F SD S R GF
Sbjct: 2019 --HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 2069
Score = 143 bits (346), Expect = 2e-33
Identities = 120/464 (25%), Positives = 198/464 (42%), Gaps = 61/464 (13%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVA-LRFHSFEVENHDTCSYDKVKVRDG--D 115
+G + SPN+P Y N C+W ++ +V L F F++E YD + V DG D
Sbjct: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQD 468
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECAS----- 169
++ + G +P I ST++++ ++F++D + GF A++ + E C
Sbjct: 469 GDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPA 528
Query: 170 --------IDHG--CSHSC---VNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
HG C +G C + + C +C P+G
Sbjct: 529 YGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGV 588
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
+ SP++PE Y +C+W I+A P+ RI L F D+E ++D + + A
Sbjct: 589 VLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP--------QFDFLVIKDGATA 640
Query: 277 DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDECAEN----N 331
+ G F G LP +TS G V R++F +D S + GF + +EC + N
Sbjct: 641 EAPVL-GTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVN 699
Query: 332 GGCQHECHNTLGGYECACHSGF--TLHPNKHDC--KEGG-------------CKHDVTLP 374
G + C GF T C KEG C +T P
Sbjct: 700 GKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSP 759
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GTI SP +P Y C W PG+ IK+ F+ F+ E + YD + + DG +
Sbjct: 760 SGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLEVRDGRTYS 815
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+G++ G+++P ++++ N +Y++F +D S GF + T
Sbjct: 816 APLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 859
Score = 139 bits (337), Expect = 2e-32
Identities = 126/467 (26%), Positives = 203/467 (43%), Gaps = 68/467 (14%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G + SPNYP+DY + C+W + + ++ L F+ +VE +D + ++DG + +
Sbjct: 586 SGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAE 641
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC---------- 167
+P++G F G+++P I S+ + + F++D + K GF+ TF +EC
Sbjct: 642 APVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGK 701
Query: 168 ---------ASIDHGCSHSCVNTLGGYECACDI---GYELHSDGKKCENACGGALYGPNG 215
+SI C + T G C + +S +CE CGG L P+G
Sbjct: 702 RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSG 761
Query: 216 TITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHS--K 273
TI SP +P Y +C W I A P + I + F F E N YD++ V
Sbjct: 762 TILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN--------YDTLEVRDGRT 813
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAEN 330
A ++ G + GT +P + S + L + F++D S GF Y + D C +
Sbjct: 814 YSAPLI---GVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDP 870
Query: 331 N---GGCQHECHNTLGG-YECACHSGFTLHPNKH-DCK------------EGGCKHDVTL 373
G +H +G +C SG+TL + +C+ E C +
Sbjct: 871 GIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQG 930
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
GTI SP +P YP +C W T+ G + F+ F H E +D++ I + S
Sbjct: 931 SSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF----HLESGHDYLLITENGSF 986
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMV---FKSDGSVQRKGFLATHS 477
+ L GS+LP + A + F SD S+ +GF T S
Sbjct: 987 -TQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1032
Score = 117 bits (281), Expect = 1e-25
Identities = 93/294 (31%), Positives = 133/294 (45%), Gaps = 34/294 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQECE 264
C L GP+G ITSP+FP Y +C+W I A P I L F FDLE
Sbjct: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG-------- 456
Query: 265 YDSVTVHSKLGADVLRRHGAF--CGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-Y 321
YD++TV G D ++ + GT++P + S + + F +DGS GF A Y
Sbjct: 457 YDTLTVGDG-GQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEE 515
Query: 322 IDVDECAE-------NNGGCQHECHNTL-----GGYECACHSGFTLHPNKH-DCKEGGCK 368
I+ C + G + +TL +E T N K+ GC
Sbjct: 516 IEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV 575
Query: 369 ----HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
+ T P G + SPNYP Y CVW P RI L FN ++EP +D
Sbjct: 576 FSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDF 631
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ I DGA+A+ LG F G++LP + +S + + F++D S ++GF T +T
Sbjct: 632 LVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 685
Score = 104 bits (250), Expect = 8e-22
Identities = 82/293 (27%), Positives = 125/293 (42%), Gaps = 37/293 (12%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G + SP +P+ Y + C+WK+ VP+ + ++ SF E + +D +
Sbjct: 1796 CGGNL-TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSL 1850
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
+V DG ++G F G +P + STSN+L + F SD +V AGF + +
Sbjct: 1851 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1910
Query: 166 ECASIDHGCSHS---CVNTLGGYECACDIGYELHSD--------------GKKCENACGG 208
E A +G VN + ++C + H+ C CGG
Sbjct: 1911 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGG 1970
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
+ G I SP FP YP +C W+I P + F +F E NH Y
Sbjct: 1971 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY--------- 2021
Query: 269 TVHSKLGA-DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + G + R G F G+ LP + S V F SD S +R GF Y
Sbjct: 2022 -IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
Score = 102 bits (244), Expect = 4e-21
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 42/289 (14%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
NG +ESP +P Y C W ++ + +++ L F SF +E +D + V DG
Sbjct: 34 NGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE----DFDVLSVFDGPPQP 89
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECAS---IDHGC 174
L G ++P I S + L + SD V GF AT+ C + + +G
Sbjct: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEALPSHTCGNPGRLPNGI 149
Query: 175 SHSCVNTLGG-YECACDIGYEL--------HSDGK------------KCENACGGALYGP 213
LG +C++G+ L H+ + + ++ACGG L G
Sbjct: 150 QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQ 209
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+G I+SP FP Y +C W I+A I L F F LE YD + V
Sbjct: 210 SGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG--------YDFLEVTGT 261
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G+ + F G +LP PV S + LR+ FTSDG+ + GF+A Y +
Sbjct: 262 EGSSLW-----FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV 305
Score = 101 bits (241), Expect = 1e-20
Identities = 92/296 (31%), Positives = 127/296 (42%), Gaps = 43/296 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
C L+GPNGT+ SP FP YP NC W I A QHRI L F F LE ++
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE--------DF 77
Query: 266 DSVTVHS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
D ++V + LR G LP + S + L ++ SD +V GF A Y
Sbjct: 78 DVLSVFDGPPQPENLRTR--LTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEALP 135
Query: 325 DECAENNG----GCQHECHNTLGG-YECACHSGFTLHPNK----HDCKEGGCKHDVTLP- 374
N G G Q LG +C+ GF L + H E D LP
Sbjct: 136 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
Query: 375 --------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
G I SP++P+ Y DC W G I L+F F+LE +
Sbjct: 196 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYD- 254
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+ VT +G+S F G+ LP V++S+N + + F SDG+ +++GF A +
Sbjct: 255 -FLEVTGTEGSSL------WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 303
Score = 94.7 bits (225), Expect = 9e-19
Identities = 120/482 (24%), Positives = 188/482 (39%), Gaps = 71/482 (14%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG I+ S+G + SP +PD Y N C W + V FH+F +E+ +
Sbjct: 921 EALCGGFIQ-GSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES----GH 975
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK- 162
D + + + S PL G ++P I + + V F SD ++ GF+ TF +
Sbjct: 976 DYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEY 1034
Query: 163 EFDECA-------SIDHGCSHSCVNTLGGYECACDIGYELHSDGK--------------- 200
+ + C SI G +TL +C GY L +
Sbjct: 1035 DLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSSPL 1091
Query: 201 -KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
+C CG ++ G GT+ SP+FP Y C++ I P I L F+L +
Sbjct: 1092 PRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVL 1151
Query: 260 QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ YD ++L + H G L S S L + F +D GF
Sbjct: 1152 KV---YDGNNNSARLLG--VFSHSEMMGVTL----NSTSSSLWLDFITDAENTSKGFELH 1202
Query: 320 YY-IDVDECAENN----GGCQH-ECHNTLGGYECACHSGFTLHPNKHD-CKEGGCKH-DV 371
+ ++ +C + G H E H +C G++L ++ C G + D
Sbjct: 1203 FSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDR 1262
Query: 372 TLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
LP G + SP YPA Y +C+W G I L F VF+ E
Sbjct: 1263 PLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE- 1321
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+D + I+DG L G LP + ++ N + + F +D ++GF S
Sbjct: 1322 ---VHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1378
Query: 478 TA 479
+
Sbjct: 1379 VS 1380
Score = 83.4 bits (197), Expect = 2e-15
Identities = 82/301 (27%), Positives = 117/301 (38%), Gaps = 37/301 (12%)
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
KCE CGG + NGT+ SP FP Y ++C+W I P H + LN + + Q
Sbjct: 2177 KCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLS--------LLQ 2228
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
E D +T+ R G F + V S + + ++F D + A
Sbjct: 2229 TEPSGDFITIWDG-PQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFS 2287
Query: 321 YIDVDECAEN----NGGC--QHECHNTLGGYECACHSGFTLHPNKH-DCKEGG------- 366
+ +C N ++E N C GFTL N+ CK G
Sbjct: 2288 AYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGP 2347
Query: 367 -------CKHDVTLPH--GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
C + L G I S +YP +YP + C W P + I L F E
Sbjct: 2348 PPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ 2407
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD I+DG S L G+ P +V +S N +Y+ + SD + RKGF +
Sbjct: 2408 ----YDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
Query: 477 S 477
S
Sbjct: 2464 S 2464
Score = 81.0 bits (191), Expect = 1e-14
Identities = 80/298 (26%), Positives = 129/298 (43%), Gaps = 37/298 (12%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 2179 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 2233
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDST---VQKAGFSA----- 158
D + + DG +P +G+F ++S+SN++L+ F D+ + FSA
Sbjct: 2234 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2293
Query: 159 ----TFMKEFD-----ECASIDHGCSHSCVN--TLGGYE-CACDIGYELHSDGKK--CEN 204
T + + E +I + C+ TL G E C +G L +G CE
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2353
Query: 205 AC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
C L G I S S+P YP + C W + P + I+L +F E Y +
Sbjct: 2354 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE--KQYDEF 2411
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+D + S L + + A P VTS + + ++++SD + +R GF Y
Sbjct: 2412 EIFDGPSGQSPLLKALSGNYSA------PLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2463
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFST-TPGHRIKLIFNVFELEPHQEC 420
C+ C + P G I SPN+P Y CVW + P IKL F F+LE
Sbjct: 400 CRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER---- 455
Query: 421 AYDHVTIYDGA-SADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD +T+ DG D KT L I G+ +P L++++ +QM+++F++DGS GF A++
Sbjct: 456 GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASY 513
Score = 72.9 bits (171), Expect = 3e-12
Identities = 35/113 (30%), Positives = 63/113 (55%), Gaps = 5/113 (4%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 1966 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 2020
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++R+G S ++G F G ++P + STS++ V F SD + + GF +
Sbjct: 2021 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEY 2073
Score = 72.1 bits (169), Expect = 5e-12
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T +GT++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +T
Sbjct: 2182 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFIT 2237
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD---GSVQRKGFLATHSTAC 480
I+DG LG+F S V +S NQ+ + F D G + F A T C
Sbjct: 2238 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2294
Score = 58.4 bits (135), Expect = 7e-08
Identities = 39/147 (26%), Positives = 62/147 (42%), Gaps = 8/147 (5%)
Query: 53 DIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVR 112
++ DS G + S +YP Y + C W + V DY ++L F E YD+ ++
Sbjct: 2359 ELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYDEFEIF 2414
Query: 113 DGDSMDSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
DG S SPL+ G + P + S+SN + + + SD + GF + +
Sbjct: 2415 DGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP 2474
Query: 172 -HG--CSHSCVNTLGGYECACDIGYEL 195
HG + G C+ GY L
Sbjct: 2475 LHGFILGQTSTQPGGSIHFGCNAGYRL 2501
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G + SP++P +Y N C W + +AL F F++E D + +V
Sbjct: 202 CGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLE--DGYDFLEV 258
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+G S+ F G +P + S+ N L + F SD ++ GFSA +
Sbjct: 259 TGTEGSSL------WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 303
Score = 51.2 bits (117), Expect = 1e-05
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 12/119 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L + + + + Y + ADC W I A + L F+ F+LE
Sbjct: 201 ACGGTLRGQSGI----ISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG---- 252
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
YD+++V F G +P ++S+ L + F +D + +GFSA YQ+ K
Sbjct: 253 YDFLEV----TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKK 307
Score = 50.4 bits (115), Expect = 2e-05
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 4/91 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + A+C W I A H ++L F +F LE + +D + VF G ++
Sbjct: 46 YPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPENLRTRLTGFQL 101
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
P IVS + L +R +D ++ +GF A+Y+
Sbjct: 102 PATIVSAATTLSLRLISDYAVSAQGFHATYE 132
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 1968 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 2019
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 2020 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2074
Score = 48.4 bits (110), Expect = 8e-05
Identities = 47/190 (24%), Positives = 74/190 (38%), Gaps = 10/190 (5%)
Query: 409 FNV-FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQ-NQMYMVFKSDGS 466
FN+ F H EC V + D LG + +Q ++ +GS
Sbjct: 679 FNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGS 738
Query: 467 VQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
V + CGG+L++ + S G Y+ C W IEA + +K+TF
Sbjct: 739 VVWNSAVLRCEAPCGGHLTSPSGT--ILSPGWPG--FYKDALSCAWVIEAQPGYPIKITF 794
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
F+ E YD ++V + G ++P ++STS L + F TD S
Sbjct: 795 DRFKTE----VNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 850
Query: 587 KGFSASYQMV 596
GF Y+ +
Sbjct: 851 IGFQLRYETI 860
Score = 48.4 bits (110), Expect = 8e-05
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y +CDW + ++ + L F F LE YD++ ++ +F G ++
Sbjct: 1465 YPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLHIYDGRDSLSPLIGSFYGSQL 1520
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+S +L + FR+D S+ GF Y
Sbjct: 1521 PGRIESSSNSLFLAFRSDASVSNAGFVIDY 1550
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--G 560
Y++ A C W I A + +KL F F+LER YD + V + G
Sbjct: 425 YDNNAHCVWIITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTG 480
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVST+ + + F+TD S GF ASY+ ++
Sbjct: 481 TSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIE 517
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I P +++ ++F E+ +D ++VF +F G +
Sbjct: 1816 YLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLEVFDGADNTVTMLGSFSGTTV 1871
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F +D S+ GF Y+ V
Sbjct: 1872 PALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1904
Score = 38.7 bits (86), Expect = 0.063
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
YE +C W IEA + L FL F+ E +D ++++ G +
Sbjct: 1292 YEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV----HDVLRIWDGPVESGVLLKELSGPAL 1347
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPT 599
P ++ ST +++++F TD +GF+ + + T
Sbjct: 1348 PKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 1383
Score = 35.5 bits (78), Expect = 0.58
Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + C W I A + L F ++E + +D++ + TF G ++
Sbjct: 598 YGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQL 653
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+ + F+TD S +GF+ ++
Sbjct: 654 PSSITSSGHVARLEFQTDHSTGKRGFNITF 683
>AL355178-1|CAI23434.1| 1167|Homo sapiens CUB and Sushi multiple
domains 2 protein.
Length = 1167
Score = 164 bits (399), Expect = 7e-40
Identities = 144/479 (30%), Positives = 218/479 (45%), Gaps = 66/479 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGGD+ S G + SPNYP+ Y P K C WK++V DY +AL F+ F +E YD
Sbjct: 356 APCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYD 410
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE-FDE 166
+ + DG SPLIG F G ++P I S+SN L + F SD++V AGF + + +
Sbjct: 411 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 470
Query: 167 C---ASIDHGCSHSCVNTLG-GYECACDIGYE----------LHSDGKK--------CEN 204
C SI +G LG C GYE L DGK C
Sbjct: 471 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 530
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG G +G + SP++P+ Y + CL+ + P + + F F N + +
Sbjct: 531 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVE---V 587
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--- 321
+D + HS+L + + G+ G +L P+ + VL ++F++ G GF VY
Sbjct: 588 HDGHSQHSRLLSSL---SGSHTGESL--PLATSNQVL-IKFSAKGLAPARGFHFVYQAVP 641
Query: 322 -IDVDECA---ENNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DC--KEGG------- 366
+C+ E G + ++G C+SG+ L + +C G
Sbjct: 642 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 701
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++T GTI SP +P Y +CVW+ G I++ F E +
Sbjct: 702 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 759
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DGA V LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 760 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 816
Score = 157 bits (382), Expect = 9e-38
Identities = 127/460 (27%), Positives = 201/460 (43%), Gaps = 63/460 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G + SP +P+ Y + C+WK+ VP+ + ++ SF E + +D +
Sbjct: 709 CGGNL-TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSL 763
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
+V DG ++G F G +P + STSN+L + F SD +V AGF + +
Sbjct: 764 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 823
Query: 166 ECASIDHGCSHS---CVNTLGGYECACDIGYELHSD--------------GKKCENACGG 208
E A +G VN + ++C + H+ C CGG
Sbjct: 824 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGG 883
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
+ G I SP FP YP +C W+I P + F +F E NH Y
Sbjct: 884 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY--------- 934
Query: 269 TVHSKLGA-DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDE 326
+ + G + R G F G+ LP + S V F SD S +R GF Y ++ E
Sbjct: 935 -IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 327 CAE----NNGGCQHECHNTLGGYECACHSGFTL--HP--------NKH------DCKEGG 366
C + NG + +N C G+ L HP N++ C E
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVP 1052
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T +GT++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +T
Sbjct: 1053 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFIT 1108
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
I+DG LG+F S V +S NQ+ + F D +
Sbjct: 1109 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA 1148
Score = 154 bits (373), Expect = 1e-36
Identities = 134/479 (27%), Positives = 211/479 (44%), Gaps = 68/479 (14%)
Query: 46 YEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ A CG + + G L SPN+P +Y N CI+ + + L+ +FE+ D
Sbjct: 7 FPAECGNSV-TGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDV-- 63
Query: 106 YDKVKVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-E 163
+KV DG++ + L+G+F + + STS+ L + F +D+ GF F E
Sbjct: 64 ---LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFE 120
Query: 164 FDECASIDHGCSHSCVNTLGGY-----ECACDIGYELHSD-------GKK---------C 202
+C V+ G + +CD GY L G++ C
Sbjct: 121 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 180
Query: 203 ENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
CGG + G +G + SP +P Y NC+W I A I L+F FD E H
Sbjct: 181 VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH---- 236
Query: 262 ECEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + + + VL + G ALP + S + + +QF++D + GFA +
Sbjct: 237 ----DVLRIWDGPVESGVLLKE--LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 290
Query: 321 YIDVDECAENNGGCQH----------------EC---HNTLGGYECAC---HSGFTLHPN 358
+ + G Q+ +C + G E +C + F P+
Sbjct: 291 SVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPS 350
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
C C D+T P G I SPNYP YP K+C W+ + +P + I L+FN+F LEP
Sbjct: 351 PPTCI-APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP-- 407
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + IYDG + +G F GS+LP + +S N +++ F+SD SV GF+ ++
Sbjct: 408 --GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 464
Score = 147 bits (356), Expect = 1e-34
Identities = 135/473 (28%), Positives = 201/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG V S+G + SPNYP +Y ++C++ ++VP+DY V +F F T D
Sbjct: 530 APCGGQY-VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALND 583
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIR-STSNKLLVIFESDSTVQKAGFSATFMK---- 162
V+V DG S S L+ G + +TSN++L+ F + GF +
Sbjct: 584 VVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 643
Query: 163 EFDECASID---HGCSHSCVNTLGGY-ECACDIGYELHSDGK------------------ 200
+C+S+ +G ++G C+ GY L +
Sbjct: 644 SATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 703
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGG L GTI SP FPE Y NC+W+IV P I + F E N
Sbjct: 704 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN---- 759
Query: 261 QECEYDSVTVHSKLGAD-VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ V GAD + G+F GT +P + S + L + F SD SV +GF
Sbjct: 760 ----WDSLEVFD--GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE 813
Query: 320 Y-YIDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEG-------- 365
Y + + C E +NG E + C G+ L + H C G
Sbjct: 814 YKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 873
Query: 366 ------GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C V G I SP +P YP+ DC W+ + G + F F EP+
Sbjct: 874 PPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN-- 931
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ I +G + +G F GS+LP ++++ ++ + F SD S R GF
Sbjct: 932 --HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 982
Score = 106 bits (254), Expect = 3e-22
Identities = 68/228 (29%), Positives = 107/228 (46%), Gaps = 26/228 (11%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 879 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 933
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++R+G S ++G F G ++P + STS++ V F SD + + GF + E E
Sbjct: 934 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 167 CA-------SIDHGCSHS-----CVNTLGGYE------CACDIGYELHSDG--KKCENAC 206
C I G ++ L GY+ C G + D KCE C
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 1053
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
GG + NGT+ SP FP Y ++C+W I P H + LN + E
Sbjct: 1054 GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 1101
Score = 62.1 bits (144), Expect = 6e-09
Identities = 73/296 (24%), Positives = 114/296 (38%), Gaps = 35/296 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG ++ G GT+ SP+FP Y C++ I P I L F+L + + Y
Sbjct: 11 CGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV---Y 67
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDV 324
D ++L + H G L S S L + F +D GF + ++
Sbjct: 68 DGNNNSARLLG--VFSHSEMMGVTL----NSTSSSLWLDFITDAENTSKGFELHFSSFEL 121
Query: 325 DECAENN----GGCQH-ECHNTLGGYECACHSGFTLHPNKHD-CKEGGCKH-DVTLP--- 374
+C + G H E H +C G++L ++ C G + D LP
Sbjct: 122 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 181
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SP YPA Y +C+W G I L F VF+ E +D
Sbjct: 182 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 237
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+ I+DG L G LP + ++ N + + F +D ++GF S +
Sbjct: 238 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS 293
Score = 60.9 bits (141), Expect = 1e-08
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 1050 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 1104
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
D + + DG +P +G+F ++S+SN++L+ F D+
Sbjct: 1105 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA 1147
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 881 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 932
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 933 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 987
Score = 48.4 bits (110), Expect = 8e-05
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y +CDW + ++ + L F F LE YD++ ++ +F G ++
Sbjct: 378 YPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLHIYDGRDSLSPLIGSFYGSQL 433
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+S +L + FR+D S+ GF Y
Sbjct: 434 PGRIESSSNSLFLAFRSDASVSNAGFVIDY 463
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I P +++ ++F E+ +D ++VF +F G +
Sbjct: 729 YLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLEVFDGADNTVTMLGSFSGTTV 784
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F +D S+ GF Y+ V
Sbjct: 785 PALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 817
Score = 38.7 bits (86), Expect = 0.063
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
YE +C W IEA + L FL F+ E +D ++++ G +
Sbjct: 205 YEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV----HDVLRIWDGPVESGVLLKELSGPAL 260
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPT 599
P ++ ST +++++F TD +GF+ + + T
Sbjct: 261 PKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 296
>AL161643-1|CAI23498.1| 1167|Homo sapiens CUB and Sushi multiple
domains 2 protein.
Length = 1167
Score = 164 bits (399), Expect = 7e-40
Identities = 144/479 (30%), Positives = 218/479 (45%), Gaps = 66/479 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGGD+ S G + SPNYP+ Y P K C WK++V DY +AL F+ F +E YD
Sbjct: 356 APCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYD 410
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE-FDE 166
+ + DG SPLIG F G ++P I S+SN L + F SD++V AGF + + +
Sbjct: 411 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 470
Query: 167 C---ASIDHGCSHSCVNTLG-GYECACDIGYE----------LHSDGKK--------CEN 204
C SI +G LG C GYE L DGK C
Sbjct: 471 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 530
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG G +G + SP++P+ Y + CL+ + P + + F F N + +
Sbjct: 531 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVE---V 587
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--- 321
+D + HS+L + + G+ G +L P+ + VL ++F++ G GF VY
Sbjct: 588 HDGHSQHSRLLSSL---SGSHTGESL--PLATSNQVL-IKFSAKGLAPARGFHFVYQAVP 641
Query: 322 -IDVDECA---ENNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DC--KEGG------- 366
+C+ E G + ++G C+SG+ L + +C G
Sbjct: 642 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 701
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++T GTI SP +P Y +CVW+ G I++ F E +
Sbjct: 702 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 759
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DGA V LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 760 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 816
Score = 157 bits (382), Expect = 9e-38
Identities = 127/460 (27%), Positives = 201/460 (43%), Gaps = 63/460 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G + SP +P+ Y + C+WK+ VP+ + ++ SF E + +D +
Sbjct: 709 CGGNL-TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSL 763
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
+V DG ++G F G +P + STSN+L + F SD +V AGF + +
Sbjct: 764 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 823
Query: 166 ECASIDHGCSHS---CVNTLGGYECACDIGYELHSD--------------GKKCENACGG 208
E A +G VN + ++C + H+ C CGG
Sbjct: 824 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGG 883
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
+ G I SP FP YP +C W+I P + F +F E NH Y
Sbjct: 884 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY--------- 934
Query: 269 TVHSKLGA-DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDE 326
+ + G + R G F G+ LP + S V F SD S +R GF Y ++ E
Sbjct: 935 -IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 327 CAE----NNGGCQHECHNTLGGYECACHSGFTL--HP--------NKH------DCKEGG 366
C + NG + +N C G+ L HP N++ C E
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVP 1052
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T +GT++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +T
Sbjct: 1053 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFIT 1108
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
I+DG LG+F S V +S NQ+ + F D +
Sbjct: 1109 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA 1148
Score = 154 bits (373), Expect = 1e-36
Identities = 134/479 (27%), Positives = 211/479 (44%), Gaps = 68/479 (14%)
Query: 46 YEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ A CG + + G L SPN+P +Y N CI+ + + L+ +FE+ D
Sbjct: 7 FPAECGNSV-TGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDV-- 63
Query: 106 YDKVKVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-E 163
+KV DG++ + L+G+F + + STS+ L + F +D+ GF F E
Sbjct: 64 ---LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFE 120
Query: 164 FDECASIDHGCSHSCVNTLGGY-----ECACDIGYELHSD-------GKK---------C 202
+C V+ G + +CD GY L G++ C
Sbjct: 121 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 180
Query: 203 ENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
CGG + G +G + SP +P Y NC+W I A I L+F FD E H
Sbjct: 181 VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH---- 236
Query: 262 ECEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + + + VL + G ALP + S + + +QF++D + GFA +
Sbjct: 237 ----DVLRIWDGPVESGVLLKE--LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 290
Query: 321 YIDVDECAENNGGCQH----------------EC---HNTLGGYECAC---HSGFTLHPN 358
+ + G Q+ +C + G E +C + F P+
Sbjct: 291 SVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPS 350
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
C C D+T P G I SPNYP YP K+C W+ + +P + I L+FN+F LEP
Sbjct: 351 PPTCI-APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP-- 407
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + IYDG + +G F GS+LP + +S N +++ F+SD SV GF+ ++
Sbjct: 408 --GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 464
Score = 147 bits (356), Expect = 1e-34
Identities = 135/473 (28%), Positives = 201/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG V S+G + SPNYP +Y ++C++ ++VP+DY V +F F T D
Sbjct: 530 APCGGQY-VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALND 583
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIR-STSNKLLVIFESDSTVQKAGFSATFMK---- 162
V+V DG S S L+ G + +TSN++L+ F + GF +
Sbjct: 584 VVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 643
Query: 163 EFDECASID---HGCSHSCVNTLGGY-ECACDIGYELHSDGK------------------ 200
+C+S+ +G ++G C+ GY L +
Sbjct: 644 SATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 703
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGG L GTI SP FPE Y NC+W+IV P I + F E N
Sbjct: 704 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN---- 759
Query: 261 QECEYDSVTVHSKLGAD-VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ V GAD + G+F GT +P + S + L + F SD SV +GF
Sbjct: 760 ----WDSLEVFD--GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE 813
Query: 320 Y-YIDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEG-------- 365
Y + + C E +NG E + C G+ L + H C G
Sbjct: 814 YKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 873
Query: 366 ------GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C V G I SP +P YP+ DC W+ + G + F F EP+
Sbjct: 874 PPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN-- 931
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ I +G + +G F GS+LP ++++ ++ + F SD S R GF
Sbjct: 932 --HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 982
Score = 106 bits (254), Expect = 3e-22
Identities = 68/228 (29%), Positives = 107/228 (46%), Gaps = 26/228 (11%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 879 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 933
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++R+G S ++G F G ++P + STS++ V F SD + + GF + E E
Sbjct: 934 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 167 CA-------SIDHGCSHS-----CVNTLGGYE------CACDIGYELHSDG--KKCENAC 206
C I G ++ L GY+ C G + D KCE C
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 1053
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
GG + NGT+ SP FP Y ++C+W I P H + LN + E
Sbjct: 1054 GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 1101
Score = 62.1 bits (144), Expect = 6e-09
Identities = 73/296 (24%), Positives = 114/296 (38%), Gaps = 35/296 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG ++ G GT+ SP+FP Y C++ I P I L F+L + + Y
Sbjct: 11 CGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV---Y 67
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDV 324
D ++L + H G L S S L + F +D GF + ++
Sbjct: 68 DGNNNSARLLG--VFSHSEMMGVTL----NSTSSSLWLDFITDAENTSKGFELHFSSFEL 121
Query: 325 DECAENN----GGCQH-ECHNTLGGYECACHSGFTLHPNKHD-CKEGGCKH-DVTLP--- 374
+C + G H E H +C G++L ++ C G + D LP
Sbjct: 122 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 181
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SP YPA Y +C+W G I L F VF+ E +D
Sbjct: 182 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 237
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+ I+DG L G LP + ++ N + + F +D ++GF S +
Sbjct: 238 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS 293
Score = 60.9 bits (141), Expect = 1e-08
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 1050 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 1104
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
D + + DG +P +G+F ++S+SN++L+ F D+
Sbjct: 1105 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA 1147
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 881 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 932
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 933 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 987
Score = 48.4 bits (110), Expect = 8e-05
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y +CDW + ++ + L F F LE YD++ ++ +F G ++
Sbjct: 378 YPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLHIYDGRDSLSPLIGSFYGSQL 433
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+S +L + FR+D S+ GF Y
Sbjct: 434 PGRIESSSNSLFLAFRSDASVSNAGFVIDY 463
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I P +++ ++F E+ +D ++VF +F G +
Sbjct: 729 YLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLEVFDGADNTVTMLGSFSGTTV 784
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F +D S+ GF Y+ V
Sbjct: 785 PALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 817
Score = 38.7 bits (86), Expect = 0.063
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
YE +C W IEA + L FL F+ E +D ++++ G +
Sbjct: 205 YEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV----HDVLRIWDGPVESGVLLKELSGPAL 260
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPT 599
P ++ ST +++++F TD +GF+ + + T
Sbjct: 261 PKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 296
>AB212622-1|BAD97692.1| 3631|Homo sapiens CSMD2 protein protein.
Length = 3631
Score = 164 bits (399), Expect = 7e-40
Identities = 144/479 (30%), Positives = 218/479 (45%), Gaps = 66/479 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGGD+ S G + SPNYP+ Y P K C WK++V DY +AL F+ F +E YD
Sbjct: 1483 APCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYD 1537
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE-FDE 166
+ + DG SPLIG F G ++P I S+SN L + F SD++V AGF + + +
Sbjct: 1538 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 1597
Query: 167 C---ASIDHGCSHSCVNTLG-GYECACDIGYE----------LHSDGKK--------CEN 204
C SI +G LG C GYE L DGK C
Sbjct: 1598 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 1657
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG G +G + SP++P+ Y + CL+ + P + + F F N + +
Sbjct: 1658 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVE---V 1714
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--- 321
+D + HS+L + + G+ G +L P+ + VL ++F++ G GF VY
Sbjct: 1715 HDGHSQHSRLLSSL---SGSHTGESL--PLATSNQVL-IKFSAKGLAPARGFHFVYQAVP 1768
Query: 322 -IDVDECA---ENNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DC--KEGG------- 366
+C+ E G + ++G C+SG+ L + +C G
Sbjct: 1769 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 1828
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++T GTI SP +P Y +CVW+ G I++ F E +
Sbjct: 1829 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 1886
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DGA V LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 1887 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1943
Score = 158 bits (383), Expect = 6e-38
Identities = 132/477 (27%), Positives = 206/477 (43%), Gaps = 66/477 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G + SP +P+ Y + C+WK+ VP+ + ++ SF E + +D +
Sbjct: 1836 CGGNL-TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSL 1890
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
+V DG ++G F G +P + STSN+L + F SD +V AGF + +
Sbjct: 1891 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 1950
Query: 166 ECASIDHGCSHS---CVNTLGGYECACDIGYELHSD--------------GKKCENACGG 208
E A +G VN + ++C + H+ C CGG
Sbjct: 1951 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGG 2010
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
+ G I SP FP YP +C W+I P + F +F E NH Y
Sbjct: 2011 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY--------- 2061
Query: 269 TVHSKLGA-DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDE 326
+ + G + R G F G+ LP + S V F SD S +R GF Y ++ E
Sbjct: 2062 -IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 2120
Query: 327 CAE----NNGGCQHECHNTLGGYECACHSGFTL--HP--------NKH------DCKEGG 366
C + NG + +N C G+ L HP N++ C E
Sbjct: 2121 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVP 2179
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T +GT++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +T
Sbjct: 2180 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFIT 2235
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD---GSVQRKGFLATHSTAC 480
I+DG LG+F S V +S NQ+ + F D G + F A T C
Sbjct: 2236 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKC 2292
Score = 157 bits (380), Expect = 1e-37
Identities = 137/475 (28%), Positives = 205/475 (43%), Gaps = 73/475 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA CGG + S G + SP +P Y+ C W + Y + + F F+ E +Y
Sbjct: 789 EAPCGGHLTSPS-GTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTE----VNY 843
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFS---ATFMKE 163
D ++VRDG + +PLIG++ G ++P + STSN L ++F +D + GF T +
Sbjct: 844 DTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ 903
Query: 164 FDECASID---HGCSHSCVNTLGG-YECACDIGYELHSDGK---------------KCEN 204
D C +G H +G +CD GY L SDG+ CE
Sbjct: 904 SDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTL-SDGEPLECEPNFQWSRALPSCEA 962
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +GTI SP FP+ YP NC W I + F F LE H Y E
Sbjct: 963 LCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITE 1022
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTS---DGSVLRVQFTSDGSVHRSGFAAVY- 320
S T LR+ G+ LP P+++ +V+F SD S+ GF +
Sbjct: 1023 NGSFT-------QPLRQ---LTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1072
Query: 321 YIDVDECAEN-------NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGG------- 366
D++ C E G Q +TL +C G+ L GG
Sbjct: 1073 EYDLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSS 1129
Query: 367 --------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
C + VT GT+ SPN+P Y +C++ T PG I+L FEL
Sbjct: 1130 PLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEG- 1188
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGF 472
D + +YDG + + LG+F S++ + + ++ + +++ F +D KGF
Sbjct: 1189 ----DVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGF 1239
Score = 153 bits (371), Expect = 2e-36
Identities = 134/477 (28%), Positives = 210/477 (44%), Gaps = 68/477 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG + + G L SPN+P +Y N CI+ + + L+ +FE+ D
Sbjct: 1136 AECGNSV-TGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDV---- 1190
Query: 108 KVKVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+KV DG++ + L+G+F + + STS+ L + F +D+ GF F E
Sbjct: 1191 -LKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELI 1249
Query: 166 ECASIDHGCSHSCVNTLGGY-----ECACDIGYELHSD-------GKK---------CEN 204
+C V+ G + +CD GY L G++ C
Sbjct: 1250 KCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVA 1309
Query: 205 ACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG + G +G + SP +P Y NC+W I A I L+F FD E H
Sbjct: 1310 ECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH------ 1363
Query: 264 EYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D + + + + VL + G ALP + S + + +QF++D + GFA + +
Sbjct: 1364 --DVLRIWDGPVESGVLLKE--LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSV 1419
Query: 323 DVDECAENNGGCQH----------------EC---HNTLGGYECAC---HSGFTLHPNKH 360
+ G Q+ +C + G E +C + F P+
Sbjct: 1420 STATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPP 1479
Query: 361 DCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C C D+T P G I SPNYP YP K+C W+ + +P + I L+FN+F LEP
Sbjct: 1480 TCI-APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP---- 1534
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + IYDG + +G F GS+LP + +S N +++ F+SD SV GF+ ++
Sbjct: 1535 GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 1591
Score = 147 bits (356), Expect = 1e-34
Identities = 135/473 (28%), Positives = 201/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG V S+G + SPNYP +Y ++C++ ++VP+DY V +F F T D
Sbjct: 1657 APCGGQY-VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALND 1710
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIR-STSNKLLVIFESDSTVQKAGFSATFMK---- 162
V+V DG S S L+ G + +TSN++L+ F + GF +
Sbjct: 1711 VVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 1770
Query: 163 EFDECASID---HGCSHSCVNTLGGY-ECACDIGYELHSDGK------------------ 200
+C+S+ +G ++G C+ GY L +
Sbjct: 1771 SATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 1830
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGG L GTI SP FPE Y NC+W+IV P I + F E N
Sbjct: 1831 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN---- 1886
Query: 261 QECEYDSVTVHSKLGAD-VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ V GAD + G+F GT +P + S + L + F SD SV +GF
Sbjct: 1887 ----WDSLEVFD--GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE 1940
Query: 320 Y-YIDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEG-------- 365
Y + + C E +NG E + C G+ L + H C G
Sbjct: 1941 YKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 2000
Query: 366 ------GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C V G I SP +P YP+ DC W+ + G + F F EP+
Sbjct: 2001 PPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN-- 2058
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ I +G + +G F GS+LP ++++ ++ + F SD S R GF
Sbjct: 2059 --HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 2109
Score = 143 bits (346), Expect = 2e-33
Identities = 120/464 (25%), Positives = 198/464 (42%), Gaps = 61/464 (13%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVA-LRFHSFEVENHDTCSYDKVKVRDG--D 115
+G + SPN+P Y N C+W ++ +V L F F++E YD + V DG D
Sbjct: 453 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER----GYDTLTVGDGGQD 508
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECAS----- 169
++ + G +P I ST++++ ++F++D + GF A++ + E C
Sbjct: 509 GDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPA 568
Query: 170 --------IDHG--CSHSC---VNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
HG C +G C + + C +C P+G
Sbjct: 569 YGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGV 628
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
+ SP++PE Y +C+W I+A P+ RI L F D+E ++D + + A
Sbjct: 629 VLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEP--------QFDFLVIKDGATA 680
Query: 277 DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDECAEN----N 331
+ G F G LP +TS G V R++F +D S + GF + +EC + N
Sbjct: 681 EAPVL-GTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVN 739
Query: 332 GGCQHECHNTLGGYECACHSGF--TLHPNKHDC--KEGG-------------CKHDVTLP 374
G + C GF T C KEG C +T P
Sbjct: 740 GKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSP 799
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GTI SP +P Y C W PG+ IK+ F+ F+ E + YD + + DG +
Sbjct: 800 SGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN----YDTLEVRDGRTYS 855
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+G++ G+++P ++++ N +Y++F +D S GF + T
Sbjct: 856 APLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYET 899
Score = 139 bits (337), Expect = 2e-32
Identities = 126/467 (26%), Positives = 203/467 (43%), Gaps = 68/467 (14%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G + SPNYP+DY + C+W + + ++ L F+ +VE +D + ++DG + +
Sbjct: 626 SGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAE 681
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC---------- 167
+P++G F G+++P I S+ + + F++D + K GF+ TF +EC
Sbjct: 682 APVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGK 741
Query: 168 ---------ASIDHGCSHSCVNTLGGYECACDI---GYELHSDGKKCENACGGALYGPNG 215
+SI C + T G C + +S +CE CGG L P+G
Sbjct: 742 RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSG 801
Query: 216 TITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHS--K 273
TI SP +P Y +C W I A P + I + F F E N YD++ V
Sbjct: 802 TILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN--------YDTLEVRDGRT 853
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAEN 330
A ++ G + GT +P + S + L + F++D S GF Y + D C +
Sbjct: 854 YSAPLI---GVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDP 910
Query: 331 N---GGCQHECHNTLGG-YECACHSGFTLHPNKH-DCK------------EGGCKHDVTL 373
G +H +G +C SG+TL + +C+ E C +
Sbjct: 911 GIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQG 970
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
GTI SP +P YP +C W T+ G + F+ F H E +D++ I + S
Sbjct: 971 SSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTF----HLESGHDYLLITENGSF 1026
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMV---FKSDGSVQRKGFLATHS 477
+ L GS+LP + A + F SD S+ +GF T S
Sbjct: 1027 -TQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFS 1072
Score = 136 bits (330), Expect = 2e-31
Identities = 128/475 (26%), Positives = 195/475 (41%), Gaps = 63/475 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 2006 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 2060
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++R+G S ++G F G ++P + STS++ V F SD + + GF + E E
Sbjct: 2061 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 2120
Query: 167 CA-------SIDHGCSHS-----CVNTLGGYE------CACDIGYELHSDG--KKCENAC 206
C I G ++ L GY+ C G + D KCE C
Sbjct: 2121 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 2180
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + NGT+ SP FP Y ++C+W I P H + LN + + Q E D
Sbjct: 2181 GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLS--------LLQTEPSGD 2232
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD---GSVHRSGFAAVYYID 323
+T+ R G F + V S + + ++F D G + F+A
Sbjct: 2233 FITIWDG-PQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2291
Query: 324 VDE---CAENNGGCQHECHNTLGGYECACHSGFTLHPNK-HDCKEG-------------- 365
++E N C GFTL N+ CK G
Sbjct: 2292 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2351
Query: 366 GCKHD--VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C + +T G I S +YP +YP + C W P + I L F E YD
Sbjct: 2352 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQ----YD 2407
Query: 424 HVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
I+DG S L G+ P +V +S N +Y+ + SD + RKGF +S
Sbjct: 2408 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYS 2462
Score = 117 bits (281), Expect = 1e-25
Identities = 93/294 (31%), Positives = 133/294 (45%), Gaps = 34/294 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQECE 264
C L GP+G ITSP+FP Y +C+W I A P I L F FDLE
Sbjct: 445 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERG-------- 496
Query: 265 YDSVTVHSKLGADVLRRHGAF--CGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-Y 321
YD++TV G D ++ + GT++P + S + + F +DGS GF A Y
Sbjct: 497 YDTLTVGDG-GQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEE 555
Query: 322 IDVDECAE-------NNGGCQHECHNTL-----GGYECACHSGFTLHPNKH-DCKEGGCK 368
I+ C + G + +TL +E T N K+ GC
Sbjct: 556 IEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV 615
Query: 369 ----HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
+ T P G + SPNYP Y CVW P RI L FN ++EP +D
Sbjct: 616 FSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDF 671
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ I DGA+A+ LG F G++LP + +S + + F++D S ++GF T +T
Sbjct: 672 LVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTT 725
Score = 103 bits (246), Expect = 3e-21
Identities = 84/289 (29%), Positives = 127/289 (43%), Gaps = 42/289 (14%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
NG +ESP +P Y C W ++ + +++ L F SF +E +D + V DG
Sbjct: 74 NGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE----DFDVLSVFDGPPQP 129
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF-MKEFDECAS---IDHGC 174
L G ++P I S + L + SD V GF AT+ + C + + +G
Sbjct: 130 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGI 189
Query: 175 SHSCVNTLGG-YECACDIGYEL--------HSDGK------------KCENACGGALYGP 213
LG +C++G+ L H+ + + ++ACGG L G
Sbjct: 190 QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQ 249
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+G I+SP FP Y +C W I+A I L F F LE YD + V
Sbjct: 250 SGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG--------YDFLEVTGT 301
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G+ + F G +LP PV S + LR+ FTSDG+ + GF+A Y +
Sbjct: 302 EGSSLW-----FTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQV 345
Score = 102 bits (245), Expect = 3e-21
Identities = 92/296 (31%), Positives = 128/296 (43%), Gaps = 43/296 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
C L+GPNGT+ SP FP YP NC W I A QHRI L F F LE ++
Sbjct: 66 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEE--------DF 117
Query: 266 DSVTVHS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
D ++V + LR G LP + S + L ++ SD +V GF A Y +
Sbjct: 118 DVLSVFDGPPQPENLRTR--LTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLP 175
Query: 325 DECAENNG----GCQHECHNTLGG-YECACHSGFTLHPNK----HDCKEGGCKHDVTLP- 374
N G G Q LG +C+ GF L + H E D LP
Sbjct: 176 SHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 235
Query: 375 --------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
G I SP++P+ Y DC W G I L+F F+LE +
Sbjct: 236 CRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYD- 294
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+ VT +G+S F G+ LP V++S+N + + F SDG+ +++GF A +
Sbjct: 295 -FLEVTGTEGSSL------WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 343
Score = 94.7 bits (225), Expect = 9e-19
Identities = 120/482 (24%), Positives = 188/482 (39%), Gaps = 71/482 (14%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG I+ S+G + SP +PD Y N C W + V FH+F +E+ +
Sbjct: 961 EALCGGFIQ-GSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLES----GH 1015
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK- 162
D + + + S PL G ++P I + + V F SD ++ GF+ TF +
Sbjct: 1016 DYLLITENGSFTQPL-RQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEY 1074
Query: 163 EFDECA-------SIDHGCSHSCVNTLGGYECACDIGYELHSDGK--------------- 200
+ + C SI G +TL +C GY L +
Sbjct: 1075 DLEPCEEPEVPAYSIRKGLQFGVGDTL---TFSCFPGYRLEGTARITCLGGRRRLWSSPL 1131
Query: 201 -KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
+C CG ++ G GT+ SP+FP Y C++ I P I L F+L +
Sbjct: 1132 PRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVL 1191
Query: 260 QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ YD ++L + H G L S S L + F +D GF
Sbjct: 1192 KV---YDGNNNSARLLG--VFSHSEMMGVTL----NSTSSSLWLDFITDAENTSKGFELH 1242
Query: 320 YY-IDVDECAENN----GGCQH-ECHNTLGGYECACHSGFTLHPNKHD-CKEGGCKH-DV 371
+ ++ +C + G H E H +C G++L ++ C G + D
Sbjct: 1243 FSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDR 1302
Query: 372 TLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
LP G + SP YPA Y +C+W G I L F VF+ E
Sbjct: 1303 PLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE- 1361
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+D + I+DG L G LP + ++ N + + F +D ++GF S
Sbjct: 1362 ---VHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFS 1418
Query: 478 TA 479
+
Sbjct: 1419 VS 1420
Score = 81.0 bits (191), Expect = 1e-14
Identities = 80/298 (26%), Positives = 129/298 (43%), Gaps = 37/298 (12%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 2177 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 2231
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDST---VQKAGFSA----- 158
D + + DG +P +G+F ++S+SN++L+ F D+ + FSA
Sbjct: 2232 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTK 2291
Query: 159 ----TFMKEFD-----ECASIDHGCSHSCVN--TLGGYE-CACDIGYELHSDGKK--CEN 204
T + + E +I + C+ TL G E C +G L +G CE
Sbjct: 2292 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEV 2351
Query: 205 AC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
C L G I S S+P YP + C W + P + I+L +F E Y +
Sbjct: 2352 HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE--KQYDEF 2409
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+D + S L + + A P VTS + + ++++SD + +R GF Y
Sbjct: 2410 EIFDGPSGQSPLLKALSGNYSA------PLIVTSSSNSVYLRWSSDHAYNRKGFKIRY 2461
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/118 (36%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFST-TPGHRIKLIFNVFELEPHQEC 420
C+ C + P G I SPN+P Y CVW + P IKL F F+LE
Sbjct: 440 CRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLER---- 495
Query: 421 AYDHVTIYDGA-SADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD +T+ DG D KT L I G+ +P L++++ +QM+++F++DGS GF A++
Sbjct: 496 GYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASY 553
Score = 58.4 bits (135), Expect = 7e-08
Identities = 39/147 (26%), Positives = 62/147 (42%), Gaps = 8/147 (5%)
Query: 53 DIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVR 112
++ DS G + S +YP Y + C W + V DY ++L F E YD+ ++
Sbjct: 2357 ELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYDEFEIF 2412
Query: 113 DGDSMDSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
DG S SPL+ G + P + S+SN + + + SD + GF + +
Sbjct: 2413 DGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP 2472
Query: 172 -HG--CSHSCVNTLGGYECACDIGYEL 195
HG + G C+ GY L
Sbjct: 2473 LHGFILGQTSTQPGGSIHFGCNAGYRL 2499
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G + SP++P +Y N C W + +AL F F++E D + +V
Sbjct: 242 CGGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLE--DGYDFLEV 298
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+G S+ F G +P + S+ N L + F SD ++ GFSA +
Sbjct: 299 TGTEGSSL------WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQY 343
Score = 51.2 bits (117), Expect = 1e-05
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + A+C W I A H ++L F +F LE + +D + VF G ++
Sbjct: 86 YPNYANCTWTITAEEQHRIQLVFQSFALEED----FDVLSVFDGPPQPENLRTRLTGFQL 141
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P IVS + L +R +D ++ +GF A+Y+++
Sbjct: 142 PATIVSAATTLSLRLISDYAVSAQGFHATYEVL 174
Score = 51.2 bits (117), Expect = 1e-05
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 12/119 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L + + + + Y + ADC W I A + L F+ F+LE
Sbjct: 241 ACGGTLRGQSGI----ISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG---- 292
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
YD+++V F G +P ++S+ L + F +D + +GFSA YQ+ K
Sbjct: 293 YDFLEV----TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKK 347
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 2008 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 2059
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 2060 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 2114
Score = 48.4 bits (110), Expect = 8e-05
Identities = 47/190 (24%), Positives = 74/190 (38%), Gaps = 10/190 (5%)
Query: 409 FNV-FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQ-NQMYMVFKSDGS 466
FN+ F H EC V + D LG + +Q ++ +GS
Sbjct: 719 FNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGS 778
Query: 467 VQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
V + CGG+L++ + S G Y+ C W IEA + +K+TF
Sbjct: 779 VVWNSAVLRCEAPCGGHLTSPSGT--ILSPGWPG--FYKDALSCAWVIEAQPGYPIKITF 834
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
F+ E YD ++V + G ++P ++STS L + F TD S
Sbjct: 835 DRFKTE----VNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSD 890
Query: 587 KGFSASYQMV 596
GF Y+ +
Sbjct: 891 IGFQLRYETI 900
Score = 48.4 bits (110), Expect = 8e-05
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y +CDW + ++ + L F F LE YD++ ++ +F G ++
Sbjct: 1505 YPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLHIYDGRDSLSPLIGSFYGSQL 1560
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+S +L + FR+D S+ GF Y
Sbjct: 1561 PGRIESSSNSLFLAFRSDASVSNAGFVIDY 1590
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--G 560
Y++ A C W I A + +KL F F+LER YD + V + G
Sbjct: 465 YDNNAHCVWIITALNPSKVIKLAFEEFDLERG----YDTLTVGDGGQDGDQKTVLYILTG 520
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVST+ + + F+TD S GF ASY+ ++
Sbjct: 521 TSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIE 557
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I P +++ ++F E+ +D ++VF +F G +
Sbjct: 1856 YLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLEVFDGADNTVTMLGSFSGTTV 1911
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F +D S+ GF Y+ V
Sbjct: 1912 PALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 1944
Score = 38.7 bits (86), Expect = 0.063
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
YE +C W IEA + L FL F+ E +D ++++ G +
Sbjct: 1332 YEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV----HDVLRIWDGPVESGVLLKELSGPAL 1387
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPT 599
P ++ ST +++++F TD +GF+ + + T
Sbjct: 1388 PKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 1423
Score = 35.5 bits (78), Expect = 0.58
Identities = 21/90 (23%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + C W I A + L F ++E + +D++ + TF G ++
Sbjct: 638 YGNHLHCVWLILARPESRIHLAFNDIDVEPQ----FDFLVIKDGATAEAPVLGTFSGNQL 693
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+ + F+TD S +GF+ ++
Sbjct: 694 PSSITSSGHVARLEFQTDHSTGKRGFNITF 723
>AB209502-1|BAD92739.1| 2966|Homo sapiens CUB and Sushi multiple
domains 1 variant protein.
Length = 2966
Score = 164 bits (399), Expect = 7e-40
Identities = 131/462 (28%), Positives = 200/462 (43%), Gaps = 67/462 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
C G+ G + SP YP+ Y N CIWK+ V + + ++ SF E + +D +
Sbjct: 1282 CSGNF-TQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSL 1336
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
++ DG + +P +G F G +P + STSN+L + F+SD +V AGF + +
Sbjct: 1337 EIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1396
Query: 166 ECA----SIDHGCSHSCVNTLGGYECACDIGYELHS----------------DGKKCENA 205
E A SI G + VN + ++C + GY L C
Sbjct: 1397 EPALPSNSIKIGDRYM-VNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1453
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G I SP FP YP +C W I P + + F +F E NH + E
Sbjct: 1454 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF---LEI 1510
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI-DV 324
+ H+ G F GT LP + S + F SD S +R GF Y ++
Sbjct: 1511 QNGPYHTS------PMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 1564
Query: 325 DECAE----NNGGCQHECHNTLGGYECACHSGFTL--HPNKHDCKEG------------- 365
C + NG + ++ C+ G+ L HP C+ G
Sbjct: 1565 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVL-TCQHGINRNWNYPFPRCD 1623
Query: 366 -GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C ++VT +GTI+SP +P YP KDC+W + PGH + + F + + E D+
Sbjct: 1624 APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDY 1679
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
+ ++DG + LG+F G+ +S NQ+ + F SD S
Sbjct: 1680 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 1721
Score = 157 bits (381), Expect = 1e-37
Identities = 141/478 (29%), Positives = 212/478 (44%), Gaps = 64/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 929 AACGGNLTGPA-GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 983
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 984 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 1042
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 1043 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1102
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 1103 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 1160
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 1161 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 1215
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 1216 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1275
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I++ F E +
Sbjct: 1276 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN--- 1332
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 1333 -WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1389
Score = 154 bits (374), Expect = 8e-37
Identities = 138/473 (29%), Positives = 211/473 (44%), Gaps = 70/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ + G L SPN+P +Y N CI+K+ + LR SF++ DT
Sbjct: 582 AECGASVK-GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT---- 636
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDI-RSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+KV DG S +G F +++ I STSN L + F ++ + GF T+ FD
Sbjct: 637 -LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS-FDL 694
Query: 167 CASIDHGCSHSC--VNTLGGYE-----CACDIGYELHSDGK----------------KCE 203
D G + + G + +C+ GY +H C
Sbjct: 695 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 754
Query: 204 NACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
CGG ++ +G I SP +P Y +C W I A P I+L+F FD E H
Sbjct: 755 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----- 809
Query: 263 CEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + V + +D+L + + G+ALP + S + L +QF SD + +SGF+ +
Sbjct: 810 ---DILKVWDGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 864
Query: 322 IDV-----DECAENNG---GCQHECHNTL-----GGYE--------CA-CHSGFTLHPNK 359
+ D NG G E +T+ GY+ C ++ F P+
Sbjct: 865 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 924
Query: 360 HDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C C ++T P G I SPNYP YP K+C W+ P I LIF F +EP
Sbjct: 925 PTC-IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP--- 980
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+YD + IY+G ++ +G + GS+ P + +S N +++ F+SD SV GF
Sbjct: 981 -SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1032
Score = 146 bits (353), Expect = 3e-34
Identities = 134/470 (28%), Positives = 194/470 (41%), Gaps = 63/470 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I ++G + SP YP Y N C W + ++L F F+ E ++D
Sbjct: 755 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 810
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF--- 164
+KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 811 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 870
Query: 165 -DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KCENA 205
++ +G + G CD GY+L K C A
Sbjct: 871 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 930
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ + Y
Sbjct: 931 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH--IY 988
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 989 EGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1041
Query: 326 ECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTLP-- 374
E + G G + LG C SG+ L P+ C +G D LP
Sbjct: 1042 EACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1101
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SPNYP Y A + C++ T P + +F F Q D
Sbjct: 1102 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTALND 1156
Query: 424 HVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 1157 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1206
Score = 140 bits (340), Expect = 1e-32
Identities = 124/476 (26%), Positives = 205/476 (43%), Gaps = 63/476 (13%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA CGG + S+G + P +P Y+ + C W + + + + F F+ E +Y
Sbjct: 235 EAPCGGHLTA-SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTE----VNY 289
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK---E 163
D ++VRDG + SPLIG + G + P + ST N + ++F +D++ GF + E
Sbjct: 290 DTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 349
Query: 164 FDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDG--------------KKCE 203
D C +D G H G +CD GY L D C+
Sbjct: 350 SDSC--LDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 407
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG + G +GT+ SP FP+ YP NC W I + + F F LE +H
Sbjct: 408 ALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSH------ 461
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YI 322
+Y +T V R G+ + + + + +++F SD S+ GF +
Sbjct: 462 DYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFISDFSISYEGFNITFSEY 520
Query: 323 DVDECAENNGGC---QHECHNTLG-GYECACHSGFTLH-PNKHDCKEGG----------- 366
D++ C + + H +G +C G+ L K C GG
Sbjct: 521 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 580
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C V GT+ SPN+P+ Y +C+++ T G I L F+L D
Sbjct: 581 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQL-----FEGD 635
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATHST 478
+ +YDG + + LG F ++L L++ ++ N +++ F ++GS +GF T+++
Sbjct: 636 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 691
Score = 136 bits (328), Expect = 3e-31
Identities = 123/466 (26%), Positives = 194/466 (41%), Gaps = 64/466 (13%)
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S+G + SPNYP++Y N C+W + ++ L F+ F+VE +D + V+D
Sbjct: 71 SSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLAVKDDGIS 126
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC--------- 167
D ++G F G+++P + S+ + + + F+SD + GF+ T+ +EC
Sbjct: 127 DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPING 186
Query: 168 ----------ASIDHGCSHSCVNTLGGYECAC---DIGYELHSDGKKCENACGGALYGPN 214
+S+ C V T G C D S +CE CGG L +
Sbjct: 187 RRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASS 246
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I P +P Y +C W I A P H I + F F Q E YD++ V
Sbjct: 247 GVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRF--------QTEVNYDTLEVRDG- 297
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN 331
A G + GT P + S G+ + + FT+D S GF Y ++ D C +
Sbjct: 298 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 357
Query: 332 GGCQHECHNTLGGYEC----ACHSGFTLHPNKHDCKEGGCKHDVTLP------------- 374
H G +C G+TL ++ E + + LP
Sbjct: 358 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGK 417
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT+ SP +P YP +C W + G +++IF+ F H E ++D++ I + S
Sbjct: 418 SGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTF----HLESSHDYLLITEDGSFS 473
Query: 435 VKTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ + GS LPH + A + F SD S+ +GF T S
Sbjct: 474 -EPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 518
Score = 122 bits (295), Expect = 3e-27
Identities = 125/473 (26%), Positives = 199/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS-Y 106
A CGG S G + SPNYP +Y ++C++ ++VP+++ V +F F+ +D +
Sbjct: 1103 APCGGQY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 1161
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KE 163
D + + S L G G +P +TSN++L+ F + S GF + +
Sbjct: 1162 DGTHAQA--RLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQAVPRT 1216
Query: 164 FD-ECASID---HGCSHSCVNTLGGY-ECACDIGYELH-SDGKKCENA------------ 205
D +C+S+ +G + G C+ GY L S C++
Sbjct: 1217 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1276
Query: 206 -----CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C G GTI SP +PE Y NC+W+I+ I + F E N
Sbjct: 1277 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1332
Query: 261 QECEYDSVTVHSKLGADVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ +H G DV R G+F GT +P + S + L + F SD SV +GF
Sbjct: 1333 ----WDSLEIHD--GGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE 1386
Query: 320 YY-IDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEGG------- 366
Y + + C E +N + + C G+TL H C G
Sbjct: 1387 YKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1446
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++ G I SP +P +YP DC W+ S G+ + F F E +
Sbjct: 1447 SPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN-- 1504
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D + I +G +G F G+ LP ++++ ++ + F SD S R+GF
Sbjct: 1505 --HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGF 1555
Score = 109 bits (263), Expect = 2e-23
Identities = 70/233 (30%), Positives = 108/233 (46%), Gaps = 26/233 (11%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + G + SP +P Y N C W++S+P Y ++F +F E ++D
Sbjct: 1452 ATCGGTLST-LGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHD 1506
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++++G SP+IG F G +P + ST+++ L+ F SD + + GF + E
Sbjct: 1507 FLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 1566
Query: 167 CA---------------SIDHGCSHSCV--NTLGGY---ECACDIGYELHSDGKKCENAC 206
C S+ S C L G+ C I + +C+ C
Sbjct: 1567 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPC 1626
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
G + NGTI SP FP+ YP LK+C+W I PP H + +NFT E + Y
Sbjct: 1627 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDY 1679
Score = 107 bits (257), Expect = 1e-22
Identities = 133/483 (27%), Positives = 199/483 (41%), Gaps = 73/483 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGG I+ S G + SP +PD Y PN L C W + V V + FH+F +E+ S
Sbjct: 407 DALCGGYIQGKS-GTVLSPGFPDFY-PNSLNCTWTIEVSHGKGVQMIFHTFHLES----S 460
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S P + G +P I++ + + F SD ++ GF+ TF
Sbjct: 461 HDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF-S 518
Query: 163 EFDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDGK---------------- 200
E+D D G S G +C +GY L K
Sbjct: 519 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 578
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+C CG ++ G GT+ SP+FP Y C+++I I L F L
Sbjct: 579 RCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQL------- 631
Query: 261 QECEYDSVTVHSKLGADVLRRH-GAFCGTALPPPV-TSDGSVLRVQFTSDGSVHRSGFAA 318
E D++ V+ G D R G F L + S + L ++F ++GS GF
Sbjct: 632 --FEGDTLKVYD--GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQL 687
Query: 319 VY-YIDVDECAE----NNG-GCQHECHNTLGGYECACHSGFTLH-PNKHDCKEGGCK-HD 370
Y D+ +C + N G + E H T +C+ G+ +H N C G + D
Sbjct: 688 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 747
Query: 371 VTLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP 416
LP G I SP YPA Y C W PG I L F VF+
Sbjct: 748 KPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD--- 804
Query: 417 HQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
E A+D + ++DG L + GS LP + ++ N + + F SD + + GF
Sbjct: 805 -TEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQF 863
Query: 477 STA 479
ST+
Sbjct: 864 STS 866
Score = 104 bits (250), Expect = 8e-22
Identities = 82/307 (26%), Positives = 127/307 (41%), Gaps = 35/307 (11%)
Query: 189 CDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF 248
C + + C +C +G I SP++PE Y NC+W I++ P RI L F
Sbjct: 47 CQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIF 106
Query: 249 THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
FD+E ++D + V G + G F G +P + S G ++R++F SD
Sbjct: 107 NDFDVEP--------QFDFLAVKDD-GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSD 157
Query: 309 GSVHRSGFAAVY-YIDVDECAEN----NG---------------GCQHECHNTLGGYECA 348
S GF Y +EC + NG C T G
Sbjct: 158 HSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESIT 217
Query: 349 C--HSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIK 406
C G + + E C +T G I P +P Y C W PGH IK
Sbjct: 218 CILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIK 277
Query: 407 LIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
+ F+ F+ E + YD + + DG ++ +G + G++ P ++++ N MY++F +D S
Sbjct: 278 ITFDRFQTEVN----YDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS 333
Query: 467 VQRKGFL 473
GFL
Sbjct: 334 RSSIGFL 340
Score = 84.2 bits (199), Expect = 1e-15
Identities = 44/121 (36%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
NK C C + T G I SPNYP Y +CVW + PG RI LIFN F++EP
Sbjct: 56 NKPSCVFS-CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ 114
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+D + + D +D+ LG F G+++P + +S + + + F+SD S +GF T++
Sbjct: 115 ----FDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYT 170
Query: 478 T 478
T
Sbjct: 171 T 171
Score = 62.9 bits (146), Expect = 3e-09
Identities = 34/102 (33%), Positives = 55/102 (53%), Gaps = 5/102 (4%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+A CG ++ NG + SP +PD+Y K CIW ++VP + V + F + E
Sbjct: 1623 DAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVN 1677
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESD 148
D + V DG +SP +G+F G+ S++N++L+ F SD
Sbjct: 1678 DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSD 1719
Score = 52.4 bits (120), Expect = 5e-06
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG+V + CGG+L+A+ V Y Y+ C+W IEA H +K
Sbjct: 222 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGY----YKDSLHCEWIIEAKPGHSIK 277
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V + G + P ++ST + + F TD+S
Sbjct: 278 ITFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS 333
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 334 RSSIGFLIHYESV 346
Score = 50.0 bits (114), Expect = 3e-05
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 465 GSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
G+V+R + + A CGG LS V + S G +Y + DC W I P +
Sbjct: 1438 GTVRRWNYPSPLCIATCGGTLSTLGGV--ILSPGFPG--SYPNNLDCTWRISLPIGYGAH 1493
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+ FL F E AN +D++++ F G +P ++ST+ L+ F +D S
Sbjct: 1494 IQFLNFSTE--AN--HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS 1549
Query: 584 LVFKGFSASYQ 594
+GF +YQ
Sbjct: 1550 QNRQGFKLAYQ 1560
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ V ++ + Y +CDW ++ + + L F +F +E
Sbjct: 930 ACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 981
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 982 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1037
Score = 39.1 bits (87), Expect = 0.047
Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L F F++E + +D++ V TF G ++
Sbjct: 84 YGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEV 139
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P ++ S+ + + F++D S +GF+ +Y
Sbjct: 140 PSQLASSGHIVRLEFQSDHSTTGRGFNITY 169
Score = 39.1 bits (87), Expect = 0.047
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ C W IEA + L F+ F+ E +D ++V+ + G +
Sbjct: 778 YDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDILKVWDGPVDSDILLKEWSGSAL 833
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P +I ST +L ++F +D + GFS +
Sbjct: 834 PEDIHSTFNSLTLQFDSDFFISKSGFSIQF 863
Score = 37.5 bits (83), Expect = 0.14
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I +++ ++F E+ +D +++ +F G +
Sbjct: 1302 YGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLEIHDGGDVTAPRLGSFSGTTV 1357
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y+ V
Sbjct: 1358 PALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1390
>AK127722-1|BAC87101.1| 1167|Homo sapiens protein ( Homo sapiens
cDNA FLJ45822 fis, clone NT2RP8001604, moderately
similar to Homo sapiens CUB and Sushi multiple domains 1
(CSMD1). ).
Length = 1167
Score = 164 bits (398), Expect = 1e-39
Identities = 144/479 (30%), Positives = 218/479 (45%), Gaps = 66/479 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGGD+ S G + SPNYP+ Y P K C WK++V DY +AL F+ F +E YD
Sbjct: 356 APCGGDLTGPS-GVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP----GYD 410
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE-FDE 166
+ + DG SPLIG F G ++P I S+SN L + F SD++V AGF + + +
Sbjct: 411 FLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRES 470
Query: 167 C---ASIDHGCSHSCVNTLG-GYECACDIGYE----------LHSDGKK--------CEN 204
C SI +G LG C GYE L DGK C
Sbjct: 471 CFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTA 530
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG G +G + SP++P+ Y + CL+ + P + + F F N + +
Sbjct: 531 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVE---V 587
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--- 321
+D + HS+L + + G+ G +L P+ + VL ++F++ G GF VY
Sbjct: 588 HDGHSQHSRLLSSL---SGSHTGGSL--PLATSNQVL-IKFSAKGLAPARGFHFVYQAVP 641
Query: 322 -IDVDECA---ENNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DC--KEGG------- 366
+C+ E G + ++G C+SG+ L + +C G
Sbjct: 642 RTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS 701
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++T GTI SP +P Y +CVW+ G I++ F E +
Sbjct: 702 APTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN-- 759
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DGA V LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 760 --WDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 816
Score = 157 bits (382), Expect = 9e-38
Identities = 127/460 (27%), Positives = 201/460 (43%), Gaps = 63/460 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G + SP +P+ Y + C+WK+ VP+ + ++ SF E + +D +
Sbjct: 709 CGGNL-TERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSL 763
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
+V DG ++G F G +P + STSN+L + F SD +V AGF + +
Sbjct: 764 EVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCP 823
Query: 166 ECASIDHGCSHS---CVNTLGGYECACDIGYELHSD--------------GKKCENACGG 208
E A +G VN + ++C + H+ C CGG
Sbjct: 824 EPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGG 883
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
+ G I SP FP YP +C W+I P + F +F E NH Y
Sbjct: 884 TVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY--------- 934
Query: 269 TVHSKLGA-DVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDE 326
+ + G + R G F G+ LP + S V F SD S +R GF Y ++ E
Sbjct: 935 -IEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 327 CAE----NNGGCQHECHNTLGGYECACHSGFTL--HP--------NKH------DCKEGG 366
C + NG + +N C G+ L HP N++ C E
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVP 1052
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T +GT++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +T
Sbjct: 1053 CGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFIT 1108
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
I+DG LG+F S V +S NQ+ + F D +
Sbjct: 1109 IWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAA 1148
Score = 155 bits (375), Expect = 6e-37
Identities = 134/479 (27%), Positives = 213/479 (44%), Gaps = 68/479 (14%)
Query: 46 YEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ A CG + + G L SPN+P +Y N CI+ + + L+ +FE+ D
Sbjct: 7 FPAECGNSVTA-TQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDV-- 63
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPD-IRSTSNKLLVIFESDSTVQKAGFSATFMK-E 163
+KV DG++ + L+G+F ++ + + STS+ L + F +D+ GF F E
Sbjct: 64 ---LKVYDGNNNSARLLGVFSHSEMMGETLNSTSSSLWLDFITDAENTSKGFELHFSSFE 120
Query: 164 FDECASIDHGCSHSCVNTLGGY-----ECACDIGYELHSD-------GKK---------C 202
+C V+ G + +CD GY L G++ C
Sbjct: 121 LIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC 180
Query: 203 ENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
CGG + G +G + SP +P Y NC+W I A I L+F FD E H
Sbjct: 181 VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH---- 236
Query: 262 ECEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + + + VL + G ALP + S + + +QF++D + GFA +
Sbjct: 237 ----DVLRIWDGPVESGVLLKE--LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF 290
Query: 321 YIDVDECAENNGGCQH----------------EC---HNTLGGYECAC---HSGFTLHPN 358
+ + G Q+ +C + G E +C + F P+
Sbjct: 291 SVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPS 350
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
C C D+T P G I SPNYP YP K+C W+ + +P + I L+FN+F LEP
Sbjct: 351 PPTCI-APCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEP-- 407
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + IYDG + +G F GS+LP + +S N +++ F+SD SV GF+ ++
Sbjct: 408 --GYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYT 464
Score = 147 bits (355), Expect = 2e-34
Identities = 135/473 (28%), Positives = 201/473 (42%), Gaps = 68/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG V S+G + SPNYP +Y ++C++ ++VP+DY V +F F T D
Sbjct: 530 APCGGQY-VGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFH-----TALND 583
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIR-STSNKLLVIFESDSTVQKAGFSATFMK---- 162
V+V DG S S L+ G + +TSN++L+ F + GF +
Sbjct: 584 VVEVHDGHSQHSRLLSSLSGSHTGGSLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRT 643
Query: 163 EFDECASID---HGCSHSCVNTLGGY-ECACDIGYELHSDGK------------------ 200
+C+S+ +G ++G C+ GY L +
Sbjct: 644 SATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAP 703
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGG L GTI SP FPE Y NC+W+IV P I + F E N
Sbjct: 704 TCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN---- 759
Query: 261 QECEYDSVTVHSKLGAD-VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ V GAD + G+F GT +P + S + L + F SD SV +GF
Sbjct: 760 ----WDSLEVFD--GADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE 813
Query: 320 Y-YIDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEG-------- 365
Y + + C E +NG E + C G+ L + H C G
Sbjct: 814 YKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 873
Query: 366 ------GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C V G I SP +P YP+ DC W+ + G + F F EP+
Sbjct: 874 PPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN-- 931
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ I +G + +G F GS+LP ++++ ++ + F SD S R GF
Sbjct: 932 --HDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGF 982
Score = 106 bits (254), Expect = 3e-22
Identities = 68/228 (29%), Positives = 107/228 (46%), Gaps = 26/228 (11%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 879 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 933
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++R+G S ++G F G ++P + STS++ V F SD + + GF + E E
Sbjct: 934 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 993
Query: 167 CA-------SIDHGCSHS-----CVNTLGGYE------CACDIGYELHSDG--KKCENAC 206
C I G ++ L GY+ C G + D KCE C
Sbjct: 994 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 1053
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
GG + NGT+ SP FP Y ++C+W I P H + LN + E
Sbjct: 1054 GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 1101
Score = 60.9 bits (141), Expect = 1e-08
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 1050 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 1104
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
D + + DG +P +G+F ++S+SN++L+ F D+
Sbjct: 1105 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA 1147
Score = 59.3 bits (137), Expect = 4e-08
Identities = 72/296 (24%), Positives = 113/296 (38%), Gaps = 35/296 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG ++ GT+ SP+FP Y C++ I P I L F+L + + Y
Sbjct: 11 CGNSVTATQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKV---Y 67
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDV 324
D ++L + H G L S S L + F +D GF + ++
Sbjct: 68 DGNNNSARLLG--VFSHSEMMGETL----NSTSSSLWLDFITDAENTSKGFELHFSSFEL 121
Query: 325 DECAENN----GGCQH-ECHNTLGGYECACHSGFTLHPNKHD-CKEGGCKH-DVTLP--- 374
+C + G H E H +C G++L ++ C G + D LP
Sbjct: 122 IKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 181
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SP YPA Y +C+W G I L F VF+ E +D
Sbjct: 182 AECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEE----VHD 237
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+ I+DG L G LP + ++ N + + F +D ++GF S +
Sbjct: 238 VLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS 293
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 881 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 932
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 933 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 987
Score = 48.4 bits (110), Expect = 8e-05
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y +CDW + ++ + L F F LE YD++ ++ +F G ++
Sbjct: 378 YPPGKECDWKVTVSPDYVIALVFNIFNLEPG----YDFLHIYDGRDSLSPLIGSFYGSQL 433
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P I S+S +L + FR+D S+ GF Y
Sbjct: 434 PGRIESSSNSLFLAFRSDASVSNAGFVIDY 463
Score = 41.1 bits (92), Expect = 0.012
Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I P +++ ++F E+ +D ++VF +F G +
Sbjct: 729 YLNSLNCVWKIVVPEGAGIQIQVVSFVTEQN----WDSLEVFDGADNTVTMLGSFSGTTV 784
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F +D S+ GF Y+ V
Sbjct: 785 PALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV 817
Score = 38.7 bits (86), Expect = 0.063
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
YE +C W IEA + L FL F+ E +D ++++ G +
Sbjct: 205 YEHNLNCIWTIEAEAGCTIGLHFLVFDTEEV----HDVLRIWDGPVESGVLLKELSGPAL 260
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPT 599
P ++ ST +++++F TD +GF+ + + T
Sbjct: 261 PKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTAT 296
>AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple
domains 3 protein.
Length = 3501
Score = 161 bits (391), Expect = 7e-39
Identities = 145/502 (28%), Positives = 218/502 (43%), Gaps = 69/502 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ S+G + SPN+P Y ++ C W ++V DY ++L F SF +E + YD
Sbjct: 1445 APCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YD 1499
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE- 166
+ + DG +SPLIG F K+P I S+SN + + F SD +V GF + + E
Sbjct: 1500 FLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRES 1559
Query: 167 C---ASIDHGCSHSCVNTLGG-YECACDIGYELH----------SDGK--------KCEN 204
C +I +G LG CD GY L DG+ C
Sbjct: 1560 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1619
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CG G GT+ SP++P+ Y NC++ I P + + F F + + +
Sbjct: 1620 PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE---V 1676
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD T S L + + G+ G +LP S G+ + ++FTS G + GF VY
Sbjct: 1677 YDGPTQQSSLLSSL---SGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHFVYQAVP 1730
Query: 325 DECAENNGGCQHECHNTLGGYECA--------CHSGFTLH----------PNK----HDC 362
+ G E A C+ G+ LH PN +D
Sbjct: 1731 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1790
Query: 363 KEG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C +T GTI SP YP Y +CVW+ + G I++ F E +
Sbjct: 1791 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1848
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+D + YDG + LG + G+ +PHL+ ++ N +Y+ F+SD SV GF + TA
Sbjct: 1849 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-TA 1905
Query: 480 CGGYLSATEEVKHLYSHARYGD 501
G L + E + S + GD
Sbjct: 1906 IG--LDSCPEPQTPSSGIKIGD 1925
Score = 157 bits (380), Expect = 1e-37
Identities = 137/469 (29%), Positives = 200/469 (42%), Gaps = 59/469 (12%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG I G + SP YP+ Y N C+WK++VP+ + ++ SF E++ +D +
Sbjct: 1798 CGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSL 1852
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
DG ++P +G + G IP + STSN L + F+SD +V AGF + D C
Sbjct: 1853 DFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 1912
Query: 169 SIDHGCSHSCVNT---LGGY-ECACDIGYEL--HSD--------------GKKCENACGG 208
S + +G CD GY L HS C CGG
Sbjct: 1913 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPTPICLAQCGG 1972
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
A+ +G I SP FP YP +C W I P + L F +F E H +Y V
Sbjct: 1973 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH------DYLEV 2026
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDEC 327
S + V+ G G +P + S + F SD S ++ GF VY + C
Sbjct: 2027 RSGSSETSTVI---GRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2083
Query: 328 AE----NNG---GCQHECHNTLG-----GYECACHSGFT-LHPNKHDCK------EGGCK 368
+ NG G T+ GY +S T LH + E C
Sbjct: 2084 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2143
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIY 428
++T +GTI+SP YP YP +DC W PG+ I + F V + EP YD +T++
Sbjct: 2144 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2199
Query: 429 DGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
DG + +G F G+ V ++ NQ+ + F SD + L+ H+
Sbjct: 2200 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHA 2248
Score = 153 bits (372), Expect = 1e-36
Identities = 134/465 (28%), Positives = 206/465 (44%), Gaps = 66/465 (14%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SP+YP+ Y N CIW + ++ L F+ F++E+ +D + V+DGDS +S
Sbjct: 589 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 644
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC----------- 167
P++G F G ++P + S S+ L + F++D ++ GF+ T+ +EC
Sbjct: 645 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARR 704
Query: 168 --------ASIDHGCSHSCVNTLGGYECACDI--GYELHSD-GKKCENACGGALYGPNGT 216
+SI C + T G C + G + S KC CGG P+G
Sbjct: 705 FGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 764
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
I SP +P Y NC W I A P H I + F F Q E YD + VH G
Sbjct: 765 ILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF--------QTELNYDVLEVHD--GP 814
Query: 277 DVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN- 331
++L G++ GT +P + S + + + FT+D S +GF Y ++ C +
Sbjct: 815 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 874
Query: 332 --GGCQHECHNTLGG-YECACHSGFTL-HPNKHDCKEGG------------CKHDVTLPH 375
G ++ ++G +C SG+ L H C++ C DV P
Sbjct: 875 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 934
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GTI SP YP YP +C W T G ++ F+ F LE H +D++ I + S
Sbjct: 935 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF-T 989
Query: 436 KTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ L GS LP + A + + F SD S+ +GF T S
Sbjct: 990 QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1034
Score = 143 bits (346), Expect = 2e-33
Identities = 124/468 (26%), Positives = 200/468 (42%), Gaps = 64/468 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLS-VPQDYQVALRFHSFEVENHDTCSYDK 108
CG +++ S G SPN+P Y N C+W ++ V + + + F F++E YD
Sbjct: 407 CGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 461
Query: 109 VKVRDGDSMDSP--LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ + DG + P ++ + G +P I S S+++ + ++D +V GF + KE ++
Sbjct: 462 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 520
Query: 167 CASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGKK--------------CENAC 206
+ D G + G+ C G+EL + C C
Sbjct: 521 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 580
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
P GT+ SP +PE Y NC+W I++ P RI L+F FDLE + + D
Sbjct: 581 LSNFAAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 640
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YIDVD 325
S + +L G F G +P +TS+ +LR++F +D S+ GF Y +
Sbjct: 641 SPE------SPIL---GTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHN 691
Query: 326 ECAENN---GGCQHECHNTLG-GYECACHSGF--TLHPNKHDC--------------KEG 365
EC + + + LG C GF T C K G
Sbjct: 692 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG 751
Query: 366 G-CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + P G I SP +P Y +C W PGH IK+ F F+ E + YD
Sbjct: 752 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 807
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+ ++DG + LG + G+++P + +S N +Y++F +D S GF
Sbjct: 808 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF 855
Score = 142 bits (343), Expect = 5e-33
Identities = 129/476 (27%), Positives = 204/476 (42%), Gaps = 65/476 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG S G + SP +P Y+ + C W + + + + F F+ E +YD
Sbjct: 752 APCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYD 806
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++V DG ++ SPL+G + G ++P + S+SN + ++F +D++ GF + +
Sbjct: 807 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 866
Query: 167 CASID-----HGCSHSCVNTLGG-YECACDIGYEL-HSDGKKCEN-------------AC 206
+ +D HG + ++G +CD GY L H + CE C
Sbjct: 867 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 926
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + GP+GTI SP +PE YP NC W + + NF F LE +H Y E
Sbjct: 927 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 986
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSD--GSV-LRVQFTSDGSVHRSGFAAVYYID 323
S T L R G+ LPP + + G+ +++F SD S+ GF +
Sbjct: 987 SFT-------QPLAR---LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEY 1036
Query: 324 VDECAENNG----GCQHECHNTLGG-YECACHSGFTLH-PNKHDCKEGG----------- 366
E E+ G G + + +G +C SG+ L ++ C GG
Sbjct: 1037 NLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1096
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C T G + SPNYP Y +C++ G I + F L D
Sbjct: 1097 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1151
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMAS-QNQMYMVFKSDGSVQRKGFLATHST 478
+ IYDG LG F G+ + L ++S NQ+++ F SD +GF +++
Sbjct: 1152 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1207
Score = 142 bits (343), Expect = 5e-33
Identities = 130/471 (27%), Positives = 198/471 (42%), Gaps = 66/471 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ G L SPNYP +Y+ N CI+ + V + + +F + D
Sbjct: 1098 AECGASA-TNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---- 1152
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+K+ DG + L+G F G + + STSN+L + F SD+ GF + E
Sbjct: 1153 -LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 1211
Query: 166 ECAS---IDHGCSHSCVNTLGGYEC--ACDIGYELHSD-------GKK---------CEN 204
C G S G C+ GY LH G++ C
Sbjct: 1212 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1271
Query: 205 ACGGALYG-PNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G +G I SP +P Y C+W I P + ++L F FD E +H +
Sbjct: 1272 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR-- 1329
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
+D + L ++ G+ +P + S +++ +QF +D + +SGFA +
Sbjct: 1330 VWDGPPENDMLLKEI-------SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1382
Query: 324 VDECAENNGGCQHECHNTLG-------------GYE------CAC---HSGFTLHPNKHD 361
V + G + N G GYE C + + P+
Sbjct: 1383 VATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPV 1442
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C ++T G I SPN+P YP +DC W + + I L F F +EP+
Sbjct: 1443 C-IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---- 1497
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD + IYDG ++ +G F SKLP + +S N M++ F+SDGSV GF
Sbjct: 1498 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1548
Score = 142 bits (343), Expect = 5e-33
Identities = 136/472 (28%), Positives = 197/472 (41%), Gaps = 67/472 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + +S+G + SP YP Y N C+W + V V+L+F +F+ E S+D
Sbjct: 1271 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1326
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++V DG + L+ G IP I ST N + + F++D + K+GF+ F
Sbjct: 1327 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV-AT 1385
Query: 168 ASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGK-----------------KCEN 204
A D G + G E CD GYEL + + C
Sbjct: 1386 ACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1445
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L G +G I SP+FP YP ++C W I + I+L F F +E N Y
Sbjct: 1446 PCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN--YDFLYI 1503
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD +S L G+F + LP + S + + + F SDGSV +GF Y +
Sbjct: 1504 YDGPDSNSPL-------IGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL 1556
Query: 325 DECAENNG--------GCQHECHNT----------LGGYE-CACHSGFTLHPNKH----D 361
E + G G ++ +T L GY C G P +
Sbjct: 1557 RESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1616
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C T GT+ SPNYP Y +CV+ + + ++F F Q
Sbjct: 1617 C-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVP---KEFVVFGQFVF--FQTSL 1670
Query: 422 YDHVTIYDGASADVKTLGIFCGSKL-PHLVMASQNQMYMVFKSDGSVQRKGF 472
+D V +YDG + L GS L ++S NQ+ + F S G + KGF
Sbjct: 1671 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1722
Score = 118 bits (285), Expect = 5e-26
Identities = 126/499 (25%), Positives = 204/499 (40%), Gaps = 68/499 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + D +G + SP +P +Y + C W +++P + V L+F +F E +D
Sbjct: 1968 AQCGGAMS-DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHD 2022
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++VR G S S +IG G +IP + ST+++ + F SD + K GF + +
Sbjct: 2023 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2082
Query: 167 CA---------------SIDHGCSHSCVN--TLGGYE---CACDIGYELHSDGKKCENAC 206
C ++ S C TL G C + + +CE C
Sbjct: 2083 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2142
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + NGTI SP +P+ YP ++C W + PP + I +NFT + Q E YD
Sbjct: 2143 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT--------VLQTEPIYD 2194
Query: 267 SVTVHSKLGADVLRRH-GAFCG-TALPPPVTSDGSVL---RVQFTSDG----SVHRSGFA 317
+TV G D G F G TAL ++ +L FT+ G S H
Sbjct: 2195 FITVWD--GPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR 2252
Query: 318 AVY---------YIDVDECAENNGGCQHEC---HNTLGGYECACHSGFTLHPNKHD--CK 363
+ D+ E +++C +G C G L + C+
Sbjct: 2253 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2312
Query: 364 EGGCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
+++ L G I SP YP +YP + C W S G+ I + F+ E +
Sbjct: 2313 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----F 2368
Query: 423 DHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
D + +YDG + L G + ++ +++++ + +D +KGF +
Sbjct: 2369 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY---IA 2425
Query: 482 GYLSATEEVKHLYSHARYG 500
Y S E H Y ++ G
Sbjct: 2426 FYCSTPESPPHGYIISQTG 2444
Score = 113 bits (272), Expect = 2e-24
Identities = 86/294 (29%), Positives = 136/294 (46%), Gaps = 34/294 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHR-ITLNFTHFDLEGNHMYQQECE 264
CG L GP+GT TSP+FP Y C+W I A ++ I +NF FDLE
Sbjct: 407 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE--------IG 458
Query: 265 YDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY- 321
YD++T+ ++G D G+ +P + S S + + +D SV GF Y
Sbjct: 459 YDTLTIGDGGEVG-DPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 517
Query: 322 IDVDECAENN----GGCQHECHNTLGGYECACHSGFTLHPNKHD-CKEGG---------- 366
I+ + C + G + + + C GF L K C+E
Sbjct: 518 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 577
Query: 367 --CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + P GT+ SP+YP Y +C+W + PG RI L FN F+LE +D
Sbjct: 578 FPCLSNFAAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 633
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ + DG S + LG F G+++P + ++ + + + F++D S+ +GF T++T
Sbjct: 634 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 687
Score = 101 bits (241), Expect = 1e-20
Identities = 92/296 (31%), Positives = 136/296 (45%), Gaps = 43/296 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G NGTI SP FP YP NC W I+A ++RI + F F LE EY
Sbjct: 28 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE--------EY 79
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D ++++ R G LPPPVTS SV ++ TSD +V GF VYY ++
Sbjct: 80 DYLSLYDGHPHPTNFR-TRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF-KVYYEELQ 137
Query: 326 ECAENNGGCQHE--CHNT---LGG-YECACHSGFTL--HP------NKHD---------- 361
+ N G + + T +G +C +G+ L HP N +
Sbjct: 138 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 197
Query: 362 CK-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C+ E C + G I SP++P Y DC W PG I LIF F++E
Sbjct: 198 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---- 253
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD++ I +G+ L G +P +++++N + + F +D + + +GF A +
Sbjct: 254 KYDYLEI-EGSEPPTIWLS---GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 305
Score = 97.9 bits (233), Expect = 1e-19
Identities = 118/482 (24%), Positives = 194/482 (40%), Gaps = 71/482 (14%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGGD+ S G + SP YP+ Y PN L C W + V V FH+F +E+H
Sbjct: 923 DALCGGDVRGPS-GTILSPGYPEFY-PNSLNCTWTVDVTHGKGVQFNFHTFHLEDH---- 976
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S PL + G +PP I + + + + F SD ++ GF+ TF +
Sbjct: 977 HDYLLITENGSFTQPLARL-TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1035
Query: 163 -EFDECASI---DHGCSHSCVNTLGG-YECACDIGYELHSDGK----------------K 201
+ C +G +G +C GY L + +
Sbjct: 1036 YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1095
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C CG + G + SP++P Y C++ I I ++ F L + +
Sbjct: 1096 CVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKI 1155
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPP-PVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + L GAF G ++ ++S + L ++F SD GF VY
Sbjct: 1156 ---YDGKDKTTHL-------LGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1205
Query: 321 Y-IDVDECAENNG----GCQHECHNTLGGYEC--ACHSGFTLHPNKH-DCKEGGCKH-DV 371
++ C E+ G G + G C+ G+TLH + C G + D
Sbjct: 1206 TSFELSHC-EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1264
Query: 372 TLPH--------------GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
LP G I SP YP Y C+W PG+ + L F F+
Sbjct: 1265 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD---- 1320
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
E ++D + ++DG + L GS +P + ++ N + + F +D + + GF S
Sbjct: 1321 TEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFS 1380
Query: 478 TA 479
++
Sbjct: 1381 SS 1382
Score = 96.3 bits (229), Expect = 3e-19
Identities = 81/298 (27%), Positives = 127/298 (42%), Gaps = 43/298 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ + F SF +E YD +
Sbjct: 28 CGGTLK-GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 82
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
+ DG + G +PP + ST + + SD V GF + + + C
Sbjct: 83 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 142
Query: 169 S-------------IDHG--CSHSCVN--TLGGYECACDIGYELHSDGK-------KCEN 204
+ D G +SCV L G+ I +++ + E+
Sbjct: 143 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 202
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG + G +G I+SPSFP Y +C W IVA P I+L FT F Q E +
Sbjct: 203 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF--------QMEEK 254
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
YD + + + G +PPP+ S+ + LR+ F +D + GF+A Y +
Sbjct: 255 YDYLEIEGSEPPTIW-----LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQV 307
Score = 94.7 bits (225), Expect = 9e-19
Identities = 87/303 (28%), Positives = 132/303 (43%), Gaps = 47/303 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG+I NG + SP YPD+Y + C W + VP + + F + E Y
Sbjct: 2139 EALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IY 2193
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF---------- 156
D + V DG +SP IG F G+ + STSN++L+ F SD T +GF
Sbjct: 2194 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQL 2251
Query: 157 ----------SATFMKEFDECASIDHGCSHSCV---NTLGGYECACDIGYELHSDGKK-- 201
+A + E DE I + C+ +G C +G L DG
Sbjct: 2252 RVCQPPPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2310
Query: 202 CENAC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
C+ C G I SP +P+ YP L+ C W I + IT+ F F +
Sbjct: 2311 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF-------F 2362
Query: 260 QQECEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA 317
Q E E+D + V+ + + VL +A +TS+G + +Q+++D ++ GF
Sbjct: 2363 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAF--NITSNGHEVFLQWSADHGNNKKGFR 2420
Query: 318 AVY 320
Y
Sbjct: 2421 IRY 2423
Score = 65.3 bits (152), Expect = 6e-10
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHR-IKLIFNVFELEPHQEC 420
CK C ++ P GT SPN+P Y + CVW + ++ I++ F F+L E
Sbjct: 402 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL----EI 457
Query: 421 AYDHVTIYDGAS-ADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD +TI DG D +T L + GS +P L+++ +QM++ ++D SV GF
Sbjct: 458 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGF 511
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ +C ++ +DS G + SP YPD Y ++C W +SV + Y + + F+ E
Sbjct: 2312 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----E 2367
Query: 106 YDKVKVRDGDSMDSP-LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+D ++V DG ++ SP LI + + +I S +++ + + +D K GF ++ +
Sbjct: 2368 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2427
Query: 165 DECASIDHGCSHSCVNTLGG-----YECACDIGYELHSDGKKCENACGGALYG 212
C++ + ++ GG ACD G+ L K C + YG
Sbjct: 2428 --CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVG---KSSAVCRKSSYG 2475
Score = 58.8 bits (136), Expect = 5e-08
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG V G + CGG+ SA V + S G Y+ +C+W IEA H +K
Sbjct: 738 DGKVMWSGLIPKCGAPCGGHFSAPSGV--ILSPGWPG--YYKDSLNCEWVIEAEPGHSIK 793
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V ++ G ++P + S+S + + F TD+S
Sbjct: 794 ITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNS 849
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 850 RSNNGFKIHYESV 862
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 12/119 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG + + + S N Y + ADC W I A + L F F++E +
Sbjct: 203 ACGGTMRGSSGIISSPSFP----NEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----K 254
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
YDY+++ G+ +PP I+S L + F TD + ++GFSA YQ+ K
Sbjct: 255 YDYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 309
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+G + SP++P++Y N C W + ++L F F++E Y
Sbjct: 201 EDACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 255
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ + + P I + G IPP I S N L + F +DS + GFSA +
Sbjct: 256 DYLEI---EGSEPPTIWL-SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 305
Score = 54.8 bits (126), Expect = 9e-07
Identities = 33/111 (29%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+GTI SP +P YP +C W +RI+++F F LE YD++++YDG
Sbjct: 36 NGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHP 91
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH----STACG 481
G LP V ++++ + SD +V GF + S++CG
Sbjct: 92 TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 142
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y DCDW I ++ + L F++F +E YD++ ++ +F K+
Sbjct: 1467 YPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSFQDSKL 1522
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
P I S+S + + FR+D S+ + GF Y+
Sbjct: 1523 PERIESSSNTMHLAFRSDGSVSYTGFHLEYK 1553
Score = 48.4 bits (110), Expect = 8e-05
Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 470 KGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTF 529
KGF+ T CGG L YG Y + A+C W I A + +++ F +F
Sbjct: 22 KGFIYT----CGGTLKGLNGTIESPGFP-YG---YPNGANCTWVIIAEERNRIQIVFQSF 73
Query: 530 ELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
LE E YDY+ ++ G +PP + ST +R +D ++ GF
Sbjct: 74 ALEEE----YDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF 129
Query: 590 SASYQ 594
Y+
Sbjct: 130 KVYYE 134
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L+F F+LE + +D++ V TF G ++
Sbjct: 600 YGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEV 655
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P + S S L + F+ D S+ +GF+ +Y
Sbjct: 656 PSHLTSNSHILRLEFQADHSMSGRGFNITY 685
Score = 42.3 bits (95), Expect = 0.005
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG +S V + S G+ Y S DC W I P V L F+ F E +
Sbjct: 1970 CGGAMSDFSGV--ILSPGFPGN--YPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIH 2021
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY++V G ++P + ST+ + F +D S +GF YQ
Sbjct: 2022 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ 2076
Score = 36.7 bits (81), Expect = 0.25
Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG ++A +YS Y D Y + DC W + P + + + F + E Y
Sbjct: 2142 CGGNITAMNGT--IYSPG-YPDE-YPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2193
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
D++ V+ F G + STS +L++F +D
Sbjct: 2194 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2235
Score = 36.3 bits (80), Expect = 0.33
Identities = 20/93 (21%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ +C W I P +++ ++F E +D + + ++ G +
Sbjct: 1818 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1873
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y +
Sbjct: 1874 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1906
Score = 34.7 bits (76), Expect = 1.0
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXX--XXXXTFCG 560
Y+S A C W I A N +++ F F+LE YD + + G
Sbjct: 427 YDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTG 482
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVS S + + +TD+S+ GF +Y+ ++
Sbjct: 483 SFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 519
>AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2
protein.
Length = 3667
Score = 161 bits (391), Expect = 7e-39
Identities = 145/502 (28%), Positives = 218/502 (43%), Gaps = 69/502 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ S+G + SPN+P Y ++ C W ++V DY ++L F SF +E + YD
Sbjct: 1546 APCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YD 1600
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE- 166
+ + DG +SPLIG F K+P I S+SN + + F SD +V GF + + E
Sbjct: 1601 FLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRES 1660
Query: 167 C---ASIDHGCSHSCVNTLGG-YECACDIGYELH----------SDGK--------KCEN 204
C +I +G LG CD GY L DG+ C
Sbjct: 1661 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1720
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CG G GT+ SP++P+ Y NC++ I P + + F F + + +
Sbjct: 1721 PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE---V 1777
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD T S L + + G+ G +LP S G+ + ++FTS G + GF VY
Sbjct: 1778 YDGPTQQSSLLSSL---SGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHFVYQAVP 1831
Query: 325 DECAENNGGCQHECHNTLGGYECA--------CHSGFTLH----------PNK----HDC 362
+ G E A C+ G+ LH PN +D
Sbjct: 1832 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1891
Query: 363 KEG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C +T GTI SP YP Y +CVW+ + G I++ F E +
Sbjct: 1892 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1949
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+D + YDG + LG + G+ +PHL+ ++ N +Y+ F+SD SV GF + TA
Sbjct: 1950 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-TA 2006
Query: 480 CGGYLSATEEVKHLYSHARYGD 501
G L + E + S + GD
Sbjct: 2007 IG--LDSCPEPQTPSSGIKIGD 2026
Score = 157 bits (380), Expect = 1e-37
Identities = 138/469 (29%), Positives = 201/469 (42%), Gaps = 59/469 (12%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG I G + SP YP+ Y N C+WK++VP+ + ++ SF E++ +D +
Sbjct: 1899 CGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSL 1953
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
DG ++P +G + G IP + STSN L + F+SD +V AGF + D C
Sbjct: 1954 DFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 2013
Query: 169 SIDHGCSHSCVNT---LGGY-ECACDIGYEL--HSD-----GKK---------CENACGG 208
S + +G CD GY L HS G C CGG
Sbjct: 2014 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGG 2073
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
A+ +G I SP FP YP +C W I P + L F +F E H +Y V
Sbjct: 2074 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH------DYLEV 2127
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDEC 327
S + V+ G G +P + S + F SD S ++ GF VY + C
Sbjct: 2128 RSGSSETSTVI---GRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2184
Query: 328 AE----NNG---GCQHECHNTLG-----GYECACHSGFT-LHPNKHDCK------EGGCK 368
+ NG G T+ GY +S T LH + E C
Sbjct: 2185 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2244
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIY 428
++T +GTI+SP YP YP +DC W PG+ I + F V + EP YD +T++
Sbjct: 2245 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2300
Query: 429 DGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
DG + +G F G+ V ++ NQ+ + F SD + L+ H+
Sbjct: 2301 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHA 2349
Score = 153 bits (372), Expect = 1e-36
Identities = 134/465 (28%), Positives = 206/465 (44%), Gaps = 66/465 (14%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SP+YP+ Y N CIW + ++ L F+ F++E+ +D + V+DGDS +S
Sbjct: 690 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 745
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC----------- 167
P++G F G ++P + S S+ L + F++D ++ GF+ T+ +EC
Sbjct: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARR 805
Query: 168 --------ASIDHGCSHSCVNTLGGYECACDI--GYELHSD-GKKCENACGGALYGPNGT 216
+SI C + T G C + G + S KC CGG P+G
Sbjct: 806 FGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 865
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
I SP +P Y NC W I A P H I + F F Q E YD + VH G
Sbjct: 866 ILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF--------QTELNYDVLEVHD--GP 915
Query: 277 DVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN- 331
++L G++ GT +P + S + + + FT+D S +GF Y ++ C +
Sbjct: 916 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 975
Query: 332 --GGCQHECHNTLGG-YECACHSGFTL-HPNKHDCKEGG------------CKHDVTLPH 375
G ++ ++G +C SG+ L H C++ C DV P
Sbjct: 976 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 1035
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GTI SP YP YP +C W T G ++ F+ F LE H +D++ I + S
Sbjct: 1036 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF-T 1090
Query: 436 KTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ L GS LP + A + + F SD S+ +GF T S
Sbjct: 1091 QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1135
Score = 143 bits (346), Expect = 2e-33
Identities = 124/468 (26%), Positives = 200/468 (42%), Gaps = 64/468 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLS-VPQDYQVALRFHSFEVENHDTCSYDK 108
CG +++ S G SPN+P Y N C+W ++ V + + + F F++E YD
Sbjct: 508 CGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 562
Query: 109 VKVRDGDSMDSP--LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ + DG + P ++ + G +P I S S+++ + ++D +V GF + KE ++
Sbjct: 563 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 621
Query: 167 CASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGKK--------------CENAC 206
+ D G + G+ C G+EL + C C
Sbjct: 622 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
P GT+ SP +PE Y NC+W I++ P RI L+F FDLE + + D
Sbjct: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YIDVD 325
S + +L G F G +P +TS+ +LR++F +D S+ GF Y +
Sbjct: 742 SPE------SPIL---GTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHN 792
Query: 326 ECAENN---GGCQHECHNTLG-GYECACHSGF--TLHPNKHDC--------------KEG 365
EC + + + LG C GF T C K G
Sbjct: 793 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG 852
Query: 366 G-CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + P G I SP +P Y +C W PGH IK+ F F+ E + YD
Sbjct: 853 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 908
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+ ++DG + LG + G+++P + +S N +Y++F +D S GF
Sbjct: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF 956
Score = 142 bits (343), Expect = 5e-33
Identities = 129/476 (27%), Positives = 204/476 (42%), Gaps = 65/476 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG S G + SP +P Y+ + C W + + + + F F+ E +YD
Sbjct: 853 APCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYD 907
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++V DG ++ SPL+G + G ++P + S+SN + ++F +D++ GF + +
Sbjct: 908 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 967
Query: 167 CASID-----HGCSHSCVNTLGG-YECACDIGYEL-HSDGKKCEN-------------AC 206
+ +D HG + ++G +CD GY L H + CE C
Sbjct: 968 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1027
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + GP+GTI SP +PE YP NC W + + NF F LE +H Y E
Sbjct: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1087
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSD--GSV-LRVQFTSDGSVHRSGFAAVYYID 323
S T L R G+ LPP + + G+ +++F SD S+ GF +
Sbjct: 1088 SFT-------QPLAR---LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEY 1137
Query: 324 VDECAENNG----GCQHECHNTLGG-YECACHSGFTLH-PNKHDCKEGG----------- 366
E E+ G G + + +G +C SG+ L ++ C GG
Sbjct: 1138 NLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C T G + SPNYP Y +C++ G I + F L D
Sbjct: 1198 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1252
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMAS-QNQMYMVFKSDGSVQRKGFLATHST 478
+ IYDG LG F G+ + L ++S NQ+++ F SD +GF +++
Sbjct: 1253 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1308
Score = 142 bits (343), Expect = 5e-33
Identities = 130/471 (27%), Positives = 198/471 (42%), Gaps = 66/471 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ G L SPNYP +Y+ N CI+ + V + + +F + D
Sbjct: 1199 AECGASA-TNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---- 1253
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+K+ DG + L+G F G + + STSN+L + F SD+ GF + E
Sbjct: 1254 -LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 1312
Query: 166 ECAS---IDHGCSHSCVNTLGGYEC--ACDIGYELHSD-------GKK---------CEN 204
C G S G C+ GY LH G++ C
Sbjct: 1313 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
Query: 205 ACGGALYG-PNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G +G I SP +P Y C+W I P + ++L F FD E +H +
Sbjct: 1373 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR-- 1430
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
+D + L ++ G+ +P + S +++ +QF +D + +SGFA +
Sbjct: 1431 VWDGPPENDMLLKEI-------SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1483
Query: 324 VDECAENNGGCQHECHNTLG-------------GYE------CAC---HSGFTLHPNKHD 361
V + G + N G GYE C + + P+
Sbjct: 1484 VATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPV 1543
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C ++T G I SPN+P YP +DC W + + I L F F +EP+
Sbjct: 1544 C-IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---- 1598
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD + IYDG ++ +G F SKLP + +S N M++ F+SDGSV GF
Sbjct: 1599 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1649
Score = 142 bits (343), Expect = 5e-33
Identities = 136/472 (28%), Positives = 197/472 (41%), Gaps = 67/472 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + +S+G + SP YP Y N C+W + V V+L+F +F+ E S+D
Sbjct: 1372 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1427
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++V DG + L+ G IP I ST N + + F++D + K+GF+ F
Sbjct: 1428 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV-AT 1486
Query: 168 ASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGK-----------------KCEN 204
A D G + G E CD GYEL + + C
Sbjct: 1487 ACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L G +G I SP+FP YP ++C W I + I+L F F +E N Y
Sbjct: 1547 PCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN--YDFLYI 1604
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD +S L G+F + LP + S + + + F SDGSV +GF Y +
Sbjct: 1605 YDGPDSNSPL-------IGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL 1657
Query: 325 DECAENNG--------GCQHECHNT----------LGGYE-CACHSGFTLHPNKH----D 361
E + G G ++ +T L GY C G P +
Sbjct: 1658 RESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1717
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C T GT+ SPNYP Y +CV+ + + ++F F Q
Sbjct: 1718 C-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVP---KEFVVFGQFVF--FQTSL 1771
Query: 422 YDHVTIYDGASADVKTLGIFCGSKL-PHLVMASQNQMYMVFKSDGSVQRKGF 472
+D V +YDG + L GS L ++S NQ+ + F S G + KGF
Sbjct: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1823
Score = 118 bits (285), Expect = 5e-26
Identities = 126/499 (25%), Positives = 204/499 (40%), Gaps = 68/499 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + D +G + SP +P +Y + C W +++P + V L+F +F E +D
Sbjct: 2069 AQCGGAMS-DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHD 2123
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++VR G S S +IG G +IP + ST+++ + F SD + K GF + +
Sbjct: 2124 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2183
Query: 167 CA---------------SIDHGCSHSCVN--TLGGYE---CACDIGYELHSDGKKCENAC 206
C ++ S C TL G C + + +CE C
Sbjct: 2184 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2243
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + NGTI SP +P+ YP ++C W + PP + I +NFT + Q E YD
Sbjct: 2244 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT--------VLQTEPIYD 2295
Query: 267 SVTVHSKLGADVLRRH-GAFCG-TALPPPVTSDGSVL---RVQFTSDG----SVHRSGFA 317
+TV G D G F G TAL ++ +L FT+ G S H
Sbjct: 2296 FITVWD--GPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR 2353
Query: 318 AVY---------YIDVDECAENNGGCQHEC---HNTLGGYECACHSGFTLHPNKHD--CK 363
+ D+ E +++C +G C G L + C+
Sbjct: 2354 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2413
Query: 364 EGGCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
+++ L G I SP YP +YP + C W S G+ I + F+ E +
Sbjct: 2414 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----F 2469
Query: 423 DHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
D + +YDG + L G + ++ +++++ + +D +KGF +
Sbjct: 2470 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY---IA 2526
Query: 482 GYLSATEEVKHLYSHARYG 500
Y S E H Y ++ G
Sbjct: 2527 FYCSTPESPPHGYIISQTG 2545
Score = 115 bits (277), Expect = 4e-25
Identities = 87/294 (29%), Positives = 137/294 (46%), Gaps = 34/294 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHR-ITLNFTHFDLEGNHMYQQECE 264
CG L GP+GT TSP+FP Y C+W I A ++ I +NF FDLE
Sbjct: 508 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE--------IG 559
Query: 265 YDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY- 321
YD++T+ ++G D G+ +P + S S + + +D SV GF Y
Sbjct: 560 YDTLTIGDGGEVG-DPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 618
Query: 322 IDVDECAENN----GGCQHECHNTLGGYECACHSGFTLHPNKHD-CKEGG---------- 366
I+ + C + G + + + C GF L K C+E
Sbjct: 619 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 678
Query: 367 --CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + T P GT+ SP+YP Y +C+W + PG RI L FN F+LE +D
Sbjct: 679 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 734
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ + DG S + LG F G+++P + ++ + + + F++D S+ +GF T++T
Sbjct: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 788
Score = 101 bits (243), Expect = 6e-21
Identities = 97/318 (30%), Positives = 143/318 (44%), Gaps = 45/318 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G NGTI SP FP YP NC W I+A ++RI + F F LE EY
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE--------EY 76
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D ++++ R G LPPPVTS SV ++ TSD +V GF VYY ++
Sbjct: 77 DYLSLYDGHPHPTNFR-TRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF-KVYYEELQ 134
Query: 326 ECAENNGGCQHE--CHNT---LGG-YECACHSGFTL--HP------NKHD---------- 361
+ N G + + T +G +C +G+ L HP N +
Sbjct: 135 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 194
Query: 362 CK-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C+ E C + G I SP++P Y DC W PG I LIF F++E
Sbjct: 195 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---- 250
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTAC 480
YD++ I +G+ L G +P +++++N + + F +D + + +GF A + +
Sbjct: 251 KYDYLEI-EGSEPPTIWLS---GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGS- 305
Query: 481 GGYLSATEEVKHLYSHAR 498
L+ T L H R
Sbjct: 306 -STLTHTTSTGELEEHNR 322
Score = 97.9 bits (233), Expect = 1e-19
Identities = 118/482 (24%), Positives = 194/482 (40%), Gaps = 71/482 (14%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGGD+ S G + SP YP+ Y PN L C W + V V FH+F +E+H
Sbjct: 1024 DALCGGDVRGPS-GTILSPGYPEFY-PNSLNCTWTVDVTHGKGVQFNFHTFHLEDH---- 1077
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S PL + G +PP I + + + + F SD ++ GF+ TF +
Sbjct: 1078 HDYLLITENGSFTQPLARL-TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1136
Query: 163 -EFDECASI---DHGCSHSCVNTLGG-YECACDIGYELHSDGK----------------K 201
+ C +G +G +C GY L + +
Sbjct: 1137 YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1196
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C CG + G + SP++P Y C++ I I ++ F L + +
Sbjct: 1197 CVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKI 1256
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPP-PVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + L GAF G ++ ++S + L ++F SD GF VY
Sbjct: 1257 ---YDGKDKTTHL-------LGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1306
Query: 321 Y-IDVDECAENNG----GCQHECHNTLGGYEC--ACHSGFTLHPNKH-DCKEGGCKH-DV 371
++ C E+ G G + G C+ G+TLH + C G + D
Sbjct: 1307 TSFELSHC-EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1365
Query: 372 TLPH--------------GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
LP G I SP YP Y C+W PG+ + L F F+
Sbjct: 1366 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD---- 1421
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
E ++D + ++DG + L GS +P + ++ N + + F +D + + GF S
Sbjct: 1422 TEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFS 1481
Query: 478 TA 479
++
Sbjct: 1482 SS 1483
Score = 95.5 bits (227), Expect = 5e-19
Identities = 81/296 (27%), Positives = 126/296 (42%), Gaps = 43/296 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ + F SF +E YD +
Sbjct: 25 CGGTLK-GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 79
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
+ DG + G +PP + ST + + SD V GF + + + C
Sbjct: 80 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Query: 169 S-------------IDHG--CSHSCVN--TLGGYECACDIGYELHSDGK-------KCEN 204
+ D G +SCV L G+ I +++ + E+
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG + G +G I+SPSFP Y +C W IVA P I+L FT F Q E +
Sbjct: 200 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF--------QMEEK 251
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + + + G +PPP+ S+ + LR+ F +D + GF+A Y
Sbjct: 252 YDYLEIEGSEPPTIW-----LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 94.7 bits (225), Expect = 9e-19
Identities = 87/303 (28%), Positives = 132/303 (43%), Gaps = 47/303 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG+I NG + SP YPD+Y + C W + VP + + F + E Y
Sbjct: 2240 EALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IY 2294
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF---------- 156
D + V DG +SP IG F G+ + STSN++L+ F SD T +GF
Sbjct: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQL 2352
Query: 157 ----------SATFMKEFDECASIDHGCSHSCV---NTLGGYECACDIGYELHSDGKK-- 201
+A + E DE I + C+ +G C +G L DG
Sbjct: 2353 RVCQPPPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2411
Query: 202 CENAC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
C+ C G I SP +P+ YP L+ C W I + IT+ F F +
Sbjct: 2412 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF-------F 2463
Query: 260 QQECEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA 317
Q E E+D + V+ + + VL +A +TS+G + +Q+++D ++ GF
Sbjct: 2464 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAF--NITSNGHEVFLQWSADHGNNKKGFR 2521
Query: 318 AVY 320
Y
Sbjct: 2522 IRY 2524
Score = 65.3 bits (152), Expect = 6e-10
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHR-IKLIFNVFELEPHQEC 420
CK C ++ P GT SPN+P Y + CVW + ++ I++ F F+L E
Sbjct: 503 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL----EI 558
Query: 421 AYDHVTIYDGAS-ADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD +TI DG D +T L + GS +P L+++ +QM++ ++D SV GF
Sbjct: 559 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGF 612
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ +C ++ +DS G + SP YPD Y ++C W +SV + Y + + F+ E
Sbjct: 2413 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----E 2468
Query: 106 YDKVKVRDGDSMDSP-LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+D ++V DG ++ SP LI + + +I S +++ + + +D K GF ++ +
Sbjct: 2469 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2528
Query: 165 DECASIDHGCSHSCVNTLGG-----YECACDIGYELHSDGKKCENACGGALYG 212
C++ + ++ GG ACD G+ L K C + YG
Sbjct: 2529 --CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVG---KSSAVCRKSSYG 2576
Score = 58.8 bits (136), Expect = 5e-08
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG V G + CGG+ SA V + S G Y+ +C+W IEA H +K
Sbjct: 839 DGKVMWSGLIPKCGAPCGGHFSAPSGV--ILSPGWPG--YYKDSLNCEWVIEAEPGHSIK 894
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V ++ G ++P + S+S + + F TD+S
Sbjct: 895 ITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNS 950
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 951 RSNNGFKIHYESV 963
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+G + SP++P++Y N C W + ++L F F++E Y
Sbjct: 198 EDACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 252
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ + + P I + G IPP I S N L + F +DS + GFSA +
Sbjct: 253 DYLEI---EGSEPPTIWL-SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 56.0 bits (129), Expect = 4e-07
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG + + + S N Y + ADC W I A + L F F++E +
Sbjct: 200 ACGGTMRGSSGIISSPSFP----NEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----K 251
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YDY+++ G+ +PP I+S L + F TD + ++GFSA YQ
Sbjct: 252 YDYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y DCDW I ++ + L F++F +E YD++ ++ +F K+
Sbjct: 1568 YPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSFQDSKL 1623
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
P I S+S + + FR+D S+ + GF Y+
Sbjct: 1624 PERIESSSNTMHLAFRSDGSVSYTGFHLEYK 1654
Score = 47.6 bits (108), Expect = 1e-04
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + A+C W I A + +++ F +F LE E YDY+ ++ G +
Sbjct: 45 YPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYLSLYDGHPHPTNFRTRLTGFHL 100
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
PP + ST +R +D ++ GF Y+
Sbjct: 101 PPPVTSTKSVFSLRLTSDFAVSAHGFKVYYE 131
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L+F F+LE + +D++ V TF G ++
Sbjct: 701 YGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEV 756
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P + S S L + F+ D S+ +GF+ +Y
Sbjct: 757 PSHLTSNSHILRLEFQADHSMSGRGFNITY 786
Score = 42.3 bits (95), Expect = 0.005
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG +S V + S G+ Y S DC W I P V L F+ F E +
Sbjct: 2071 CGGAMSDFSGV--ILSPGFPGN--YPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIH 2122
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY++V G ++P + ST+ + F +D S +GF YQ
Sbjct: 2123 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ 2177
Score = 36.7 bits (81), Expect = 0.25
Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG ++A +YS Y D Y + DC W + P + + + F + E Y
Sbjct: 2243 CGGNITAMNGT--IYSPG-YPDE-YPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2294
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
D++ V+ F G + STS +L++F +D
Sbjct: 2295 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2336
Score = 36.3 bits (80), Expect = 0.33
Identities = 20/93 (21%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ +C W I P +++ ++F E +D + + ++ G +
Sbjct: 1919 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 1974
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y +
Sbjct: 1975 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2007
Score = 34.7 bits (76), Expect = 1.0
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXX--XXXXTFCG 560
Y+S A C W I A N +++ F F+LE YD + + G
Sbjct: 528 YDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTG 583
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVS S + + +TD+S+ GF +Y+ ++
Sbjct: 584 SFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 620
>AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1
protein.
Length = 3707
Score = 161 bits (391), Expect = 7e-39
Identities = 145/502 (28%), Positives = 218/502 (43%), Gaps = 69/502 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ S+G + SPN+P Y ++ C W ++V DY ++L F SF +E + YD
Sbjct: 1586 APCGGNL-TGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN----YD 1640
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE- 166
+ + DG +SPLIG F K+P I S+SN + + F SD +V GF + + E
Sbjct: 1641 FLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRES 1700
Query: 167 C---ASIDHGCSHSCVNTLGG-YECACDIGYELH----------SDGK--------KCEN 204
C +I +G LG CD GY L DG+ C
Sbjct: 1701 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA 1760
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CG G GT+ SP++P+ Y NC++ I P + + F F + + +
Sbjct: 1761 PCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE---V 1817
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD T S L + + G+ G +LP S G+ + ++FTS G + GF VY
Sbjct: 1818 YDGPTQQSSLLSSL---SGSHSGESLP---LSSGNQITIRFTSVGPITAKGFHFVYQAVP 1871
Query: 325 DECAENNGGCQHECHNTLGGYECA--------CHSGFTLH----------PNK----HDC 362
+ G E A C+ G+ LH PN +D
Sbjct: 1872 RTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDS 1931
Query: 363 KEG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C +T GTI SP YP Y +CVW+ + G I++ F E +
Sbjct: 1932 LPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN-- 1989
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+D + YDG + LG + G+ +PHL+ ++ N +Y+ F+SD SV GF + TA
Sbjct: 1990 --WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-TA 2046
Query: 480 CGGYLSATEEVKHLYSHARYGD 501
G L + E + S + GD
Sbjct: 2047 IG--LDSCPEPQTPSSGIKIGD 2066
Score = 157 bits (380), Expect = 1e-37
Identities = 138/469 (29%), Positives = 201/469 (42%), Gaps = 59/469 (12%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG I G + SP YP+ Y N C+WK++VP+ + ++ SF E++ +D +
Sbjct: 1939 CGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSL 1993
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
DG ++P +G + G IP + STSN L + F+SD +V AGF + D C
Sbjct: 1994 DFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 2053
Query: 169 SIDHGCSHSCVNT---LGGY-ECACDIGYEL--HSD-----GKK---------CENACGG 208
S + +G CD GY L HS G C CGG
Sbjct: 2054 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGG 2113
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
A+ +G I SP FP YP +C W I P + L F +F E H +Y V
Sbjct: 2114 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH------DYLEV 2167
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDEC 327
S + V+ G G +P + S + F SD S ++ GF VY + C
Sbjct: 2168 RSGSSETSTVI---GRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 2224
Query: 328 AE----NNG---GCQHECHNTLG-----GYECACHSGFT-LHPNKHDCK------EGGCK 368
+ NG G T+ GY +S T LH + E C
Sbjct: 2225 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 2284
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIY 428
++T +GTI+SP YP YP +DC W PG+ I + F V + EP YD +T++
Sbjct: 2285 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 2340
Query: 429 DGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
DG + +G F G+ V ++ NQ+ + F SD + L+ H+
Sbjct: 2341 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHA 2389
Score = 153 bits (372), Expect = 1e-36
Identities = 134/465 (28%), Positives = 206/465 (44%), Gaps = 66/465 (14%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SP+YP+ Y N CIW + ++ L F+ F++E+ +D + V+DGDS +S
Sbjct: 730 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 785
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC----------- 167
P++G F G ++P + S S+ L + F++D ++ GF+ T+ +EC
Sbjct: 786 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARR 845
Query: 168 --------ASIDHGCSHSCVNTLGGYECACDI--GYELHSD-GKKCENACGGALYGPNGT 216
+SI C + T G C + G + S KC CGG P+G
Sbjct: 846 FGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 905
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
I SP +P Y NC W I A P H I + F F Q E YD + VH G
Sbjct: 906 ILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF--------QTELNYDVLEVHD--GP 955
Query: 277 DVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN- 331
++L G++ GT +P + S + + + FT+D S +GF Y ++ C +
Sbjct: 956 NLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 1015
Query: 332 --GGCQHECHNTLGG-YECACHSGFTL-HPNKHDCKEGG------------CKHDVTLPH 375
G ++ ++G +C SG+ L H C++ C DV P
Sbjct: 1016 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 1075
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GTI SP YP YP +C W T G ++ F+ F LE H +D++ I + S
Sbjct: 1076 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF-T 1130
Query: 436 KTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ L GS LP + A + + F SD S+ +GF T S
Sbjct: 1131 QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 1175
Score = 143 bits (346), Expect = 2e-33
Identities = 124/468 (26%), Positives = 200/468 (42%), Gaps = 64/468 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLS-VPQDYQVALRFHSFEVENHDTCSYDK 108
CG +++ S G SPN+P Y N C+W ++ V + + + F F++E YD
Sbjct: 548 CGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDT 602
Query: 109 VKVRDGDSMDSP--LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ + DG + P ++ + G +P I S S+++ + ++D +V GF + KE ++
Sbjct: 603 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY-KEIEK 661
Query: 167 CASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGKK--------------CENAC 206
+ D G + G+ C G+EL + C C
Sbjct: 662 ESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 721
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
P GT+ SP +PE Y NC+W I++ P RI L+F FDLE + + D
Sbjct: 722 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 781
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YIDVD 325
S + +L G F G +P +TS+ +LR++F +D S+ GF Y +
Sbjct: 782 SPE------SPIL---GTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHN 832
Query: 326 ECAENN---GGCQHECHNTLG-GYECACHSGF--TLHPNKHDC--------------KEG 365
EC + + + LG C GF T C K G
Sbjct: 833 ECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG 892
Query: 366 G-CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + P G I SP +P Y +C W PGH IK+ F F+ E + YD
Sbjct: 893 APCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN----YDV 948
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+ ++DG + LG + G+++P + +S N +Y++F +D S GF
Sbjct: 949 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF 996
Score = 142 bits (343), Expect = 5e-33
Identities = 129/476 (27%), Positives = 204/476 (42%), Gaps = 65/476 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG S G + SP +P Y+ + C W + + + + F F+ E +YD
Sbjct: 893 APCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYD 947
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++V DG ++ SPL+G + G ++P + S+SN + ++F +D++ GF + +
Sbjct: 948 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 1007
Query: 167 CASID-----HGCSHSCVNTLGG-YECACDIGYEL-HSDGKKCEN-------------AC 206
+ +D HG + ++G +CD GY L H + CE C
Sbjct: 1008 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1067
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + GP+GTI SP +PE YP NC W + + NF F LE +H Y E
Sbjct: 1068 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1127
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSD--GSV-LRVQFTSDGSVHRSGFAAVYYID 323
S T L R G+ LPP + + G+ +++F SD S+ GF +
Sbjct: 1128 SFT-------QPLAR---LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEY 1177
Query: 324 VDECAENNG----GCQHECHNTLGG-YECACHSGFTLH-PNKHDCKEGG----------- 366
E E+ G G + + +G +C SG+ L ++ C GG
Sbjct: 1178 NLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C T G + SPNYP Y +C++ G I + F L D
Sbjct: 1238 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 1292
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMAS-QNQMYMVFKSDGSVQRKGFLATHST 478
+ IYDG LG F G+ + L ++S NQ+++ F SD +GF +++
Sbjct: 1293 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 1348
Score = 142 bits (343), Expect = 5e-33
Identities = 130/471 (27%), Positives = 198/471 (42%), Gaps = 66/471 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ G L SPNYP +Y+ N CI+ + V + + +F + D
Sbjct: 1239 AECGASA-TNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---- 1293
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+K+ DG + L+G F G + + STSN+L + F SD+ GF + E
Sbjct: 1294 -LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 1352
Query: 166 ECAS---IDHGCSHSCVNTLGGYEC--ACDIGYELHSD-------GKK---------CEN 204
C G S G C+ GY LH G++ C
Sbjct: 1353 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1412
Query: 205 ACGGALYG-PNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G +G I SP +P Y C+W I P + ++L F FD E +H +
Sbjct: 1413 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILR-- 1470
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
+D + L ++ G+ +P + S +++ +QF +D + +SGFA +
Sbjct: 1471 VWDGPPENDMLLKEI-------SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 1523
Query: 324 VDECAENNGGCQHECHNTLG-------------GYE------CAC---HSGFTLHPNKHD 361
V + G + N G GYE C + + P+
Sbjct: 1524 VATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPV 1583
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C ++T G I SPN+P YP +DC W + + I L F F +EP+
Sbjct: 1584 C-IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---- 1638
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD + IYDG ++ +G F SKLP + +S N M++ F+SDGSV GF
Sbjct: 1639 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1689
Score = 142 bits (343), Expect = 5e-33
Identities = 136/472 (28%), Positives = 197/472 (41%), Gaps = 67/472 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + +S+G + SP YP Y N C+W + V V+L+F +F+ E S+D
Sbjct: 1412 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 1467
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++V DG + L+ G IP I ST N + + F++D + K+GF+ F
Sbjct: 1468 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV-AT 1526
Query: 168 ASIDHGCSHSCVNTLGGYE------CACDIGYELHSDGK-----------------KCEN 204
A D G + G E CD GYEL + + C
Sbjct: 1527 ACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1586
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L G +G I SP+FP YP ++C W I + I+L F F +E N Y
Sbjct: 1587 PCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN--YDFLYI 1644
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD +S L G+F + LP + S + + + F SDGSV +GF Y +
Sbjct: 1645 YDGPDSNSPL-------IGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL 1697
Query: 325 DECAENNG--------GCQHECHNT----------LGGYE-CACHSGFTLHPNKH----D 361
E + G G ++ +T L GY C G P +
Sbjct: 1698 RESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1757
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C T GT+ SPNYP Y +CV+ + + ++F F Q
Sbjct: 1758 C-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVP---KEFVVFGQFVF--FQTSL 1811
Query: 422 YDHVTIYDGASADVKTLGIFCGSKL-PHLVMASQNQMYMVFKSDGSVQRKGF 472
+D V +YDG + L GS L ++S NQ+ + F S G + KGF
Sbjct: 1812 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGF 1863
Score = 118 bits (285), Expect = 5e-26
Identities = 126/499 (25%), Positives = 204/499 (40%), Gaps = 68/499 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + D +G + SP +P +Y + C W +++P + V L+F +F E +D
Sbjct: 2109 AQCGGAMS-DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHD 2163
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++VR G S S +IG G +IP + ST+++ + F SD + K GF + +
Sbjct: 2164 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 2223
Query: 167 CA---------------SIDHGCSHSCVN--TLGGYE---CACDIGYELHSDGKKCENAC 206
C ++ S C TL G C + + +CE C
Sbjct: 2224 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 2283
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + NGTI SP +P+ YP ++C W + PP + I +NFT + Q E YD
Sbjct: 2284 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT--------VLQTEPIYD 2335
Query: 267 SVTVHSKLGADVLRRH-GAFCG-TALPPPVTSDGSVL---RVQFTSDG----SVHRSGFA 317
+TV G D G F G TAL ++ +L FT+ G S H
Sbjct: 2336 FITVWD--GPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR 2393
Query: 318 AVY---------YIDVDECAENNGGCQHEC---HNTLGGYECACHSGFTLHPNKHD--CK 363
+ D+ E +++C +G C G L + C+
Sbjct: 2394 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 2453
Query: 364 EGGCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
+++ L G I SP YP +YP + C W S G+ I + F+ E +
Sbjct: 2454 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----F 2509
Query: 423 DHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
D + +YDG + L G + ++ +++++ + +D +KGF +
Sbjct: 2510 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY---IA 2566
Query: 482 GYLSATEEVKHLYSHARYG 500
Y S E H Y ++ G
Sbjct: 2567 FYCSTPESPPHGYIISQTG 2585
Score = 115 bits (277), Expect = 4e-25
Identities = 87/294 (29%), Positives = 137/294 (46%), Gaps = 34/294 (11%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHR-ITLNFTHFDLEGNHMYQQECE 264
CG L GP+GT TSP+FP Y C+W I A ++ I +NF FDLE
Sbjct: 548 CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLE--------IG 599
Query: 265 YDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY- 321
YD++T+ ++G D G+ +P + S S + + +D SV GF Y
Sbjct: 600 YDTLTIGDGGEVG-DPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKE 658
Query: 322 IDVDECAENN----GGCQHECHNTLGGYECACHSGFTLHPNKHD-CKEGG---------- 366
I+ + C + G + + + C GF L K C+E
Sbjct: 659 IEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICI 718
Query: 367 --CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C + T P GT+ SP+YP Y +C+W + PG RI L FN F+LE +D
Sbjct: 719 FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDF 774
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ + DG S + LG F G+++P + ++ + + + F++D S+ +GF T++T
Sbjct: 775 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 828
Score = 101 bits (243), Expect = 6e-21
Identities = 97/318 (30%), Positives = 143/318 (44%), Gaps = 45/318 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G NGTI SP FP YP NC W I+A ++RI + F F LE EY
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE--------EY 116
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D ++++ R G LPPPVTS SV ++ TSD +V GF VYY ++
Sbjct: 117 DYLSLYDGHPHPTNFR-TRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF-KVYYEELQ 174
Query: 326 ECAENNGGCQHE--CHNT---LGG-YECACHSGFTL--HP------NKHD---------- 361
+ N G + + T +G +C +G+ L HP N +
Sbjct: 175 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 234
Query: 362 CK-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C+ E C + G I SP++P Y DC W PG I LIF F++E
Sbjct: 235 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---- 290
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTAC 480
YD++ I +G+ L G +P +++++N + + F +D + + +GF A + +
Sbjct: 291 KYDYLEI-EGSEPPTIWLS---GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGS- 345
Query: 481 GGYLSATEEVKHLYSHAR 498
L+ T L H R
Sbjct: 346 -STLTHTTSTGELEEHNR 362
Score = 97.9 bits (233), Expect = 1e-19
Identities = 118/482 (24%), Positives = 194/482 (40%), Gaps = 71/482 (14%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGGD+ S G + SP YP+ Y PN L C W + V V FH+F +E+H
Sbjct: 1064 DALCGGDVRGPS-GTILSPGYPEFY-PNSLNCTWTVDVTHGKGVQFNFHTFHLEDH---- 1117
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S PL + G +PP I + + + + F SD ++ GF+ TF +
Sbjct: 1118 HDYLLITENGSFTQPLARL-TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1176
Query: 163 -EFDECASI---DHGCSHSCVNTLGG-YECACDIGYELHSDGK----------------K 201
+ C +G +G +C GY L + +
Sbjct: 1177 YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1236
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C CG + G + SP++P Y C++ I I ++ F L + +
Sbjct: 1237 CVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKI 1296
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPP-PVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + L GAF G ++ ++S + L ++F SD GF VY
Sbjct: 1297 ---YDGKDKTTHL-------LGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVY 1346
Query: 321 Y-IDVDECAENNG----GCQHECHNTLGGYEC--ACHSGFTLHPNKH-DCKEGGCKH-DV 371
++ C E+ G G + G C+ G+TLH + C G + D
Sbjct: 1347 TSFELSHC-EDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDY 1405
Query: 372 TLPH--------------GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
LP G I SP YP Y C+W PG+ + L F F+
Sbjct: 1406 PLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFD---- 1461
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
E ++D + ++DG + L GS +P + ++ N + + F +D + + GF S
Sbjct: 1462 TEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFS 1521
Query: 478 TA 479
++
Sbjct: 1522 SS 1523
Score = 95.5 bits (227), Expect = 5e-19
Identities = 81/296 (27%), Positives = 126/296 (42%), Gaps = 43/296 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ + F SF +E YD +
Sbjct: 65 CGGTLK-GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 119
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
+ DG + G +PP + ST + + SD V GF + + + C
Sbjct: 120 SLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 169 S-------------IDHG--CSHSCVN--TLGGYECACDIGYELHSDGK-------KCEN 204
+ D G +SCV L G+ I +++ + E+
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG + G +G I+SPSFP Y +C W IVA P I+L FT F Q E +
Sbjct: 240 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF--------QMEEK 291
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + + + G +PPP+ S+ + LR+ F +D + GF+A Y
Sbjct: 292 YDYLEIEGSEPPTIW-----LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 94.7 bits (225), Expect = 9e-19
Identities = 87/303 (28%), Positives = 132/303 (43%), Gaps = 47/303 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG+I NG + SP YPD+Y + C W + VP + + F + E Y
Sbjct: 2280 EALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IY 2334
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF---------- 156
D + V DG +SP IG F G+ + STSN++L+ F SD T +GF
Sbjct: 2335 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQL 2392
Query: 157 ----------SATFMKEFDECASIDHGCSHSCV---NTLGGYECACDIGYELHSDGKK-- 201
+A + E DE I + C+ +G C +G L DG
Sbjct: 2393 RVCQPPPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 2451
Query: 202 CENAC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
C+ C G I SP +P+ YP L+ C W I + IT+ F F +
Sbjct: 2452 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF-------F 2503
Query: 260 QQECEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA 317
Q E E+D + V+ + + VL +A +TS+G + +Q+++D ++ GF
Sbjct: 2504 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAF--NITSNGHEVFLQWSADHGNNKKGFR 2561
Query: 318 AVY 320
Y
Sbjct: 2562 IRY 2564
Score = 65.3 bits (152), Expect = 6e-10
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 7/114 (6%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHR-IKLIFNVFELEPHQEC 420
CK C ++ P GT SPN+P Y + CVW + ++ I++ F F+L E
Sbjct: 543 CKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDL----EI 598
Query: 421 AYDHVTIYDGAS-ADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD +TI DG D +T L + GS +P L+++ +QM++ ++D SV GF
Sbjct: 599 GYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGF 652
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ +C ++ +DS G + SP YPD Y ++C W +SV + Y + + F+ E
Sbjct: 2453 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----E 2508
Query: 106 YDKVKVRDGDSMDSP-LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+D ++V DG ++ SP LI + + +I S +++ + + +D K GF ++ +
Sbjct: 2509 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 2568
Query: 165 DECASIDHGCSHSCVNTLGG-----YECACDIGYELHSDGKKCENACGGALYG 212
C++ + ++ GG ACD G+ L K C + YG
Sbjct: 2569 --CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVG---KSSAVCRKSSYG 2616
Score = 58.8 bits (136), Expect = 5e-08
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG V G + CGG+ SA V + S G Y+ +C+W IEA H +K
Sbjct: 879 DGKVMWSGLIPKCGAPCGGHFSAPSGV--ILSPGWPG--YYKDSLNCEWVIEAEPGHSIK 934
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V ++ G ++P + S+S + + F TD+S
Sbjct: 935 ITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNS 990
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 991 RSNNGFKIHYESV 1003
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+G + SP++P++Y N C W + ++L F F++E Y
Sbjct: 238 EDACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 292
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ + + P I + G IPP I S N L + F +DS + GFSA +
Sbjct: 293 DYLEI---EGSEPPTIWL-SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 56.0 bits (129), Expect = 4e-07
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG + + + S N Y + ADC W I A + L F F++E +
Sbjct: 240 ACGGTMRGSSGIISSPSFP----NEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----K 291
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YDY+++ G+ +PP I+S L + F TD + ++GFSA YQ
Sbjct: 292 YDYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 53.2 bits (122), Expect = 3e-06
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y DCDW I ++ + L F++F +E YD++ ++ +F K+
Sbjct: 1608 YPHSRDCDWTITVNADYVISLAFISFSIEPN----YDFLYIYDGPDSNSPLIGSFQDSKL 1663
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
P I S+S + + FR+D S+ + GF Y+
Sbjct: 1664 PERIESSSNTMHLAFRSDGSVSYTGFHLEYK 1694
Score = 48.4 bits (110), Expect = 8e-05
Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 470 KGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTF 529
KGF+ T CGG L YG Y + A+C W I A + +++ F +F
Sbjct: 59 KGFIYT----CGGTLKGLNGTIESPGFP-YG---YPNGANCTWVIIAEERNRIQIVFQSF 110
Query: 530 ELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
LE E YDY+ ++ G +PP + ST +R +D ++ GF
Sbjct: 111 ALEEE----YDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF 166
Query: 590 SASYQ 594
Y+
Sbjct: 167 KVYYE 171
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L+F F+LE + +D++ V TF G ++
Sbjct: 741 YGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEV 796
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P + S S L + F+ D S+ +GF+ +Y
Sbjct: 797 PSHLTSNSHILRLEFQADHSMSGRGFNITY 826
Score = 42.3 bits (95), Expect = 0.005
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG +S V + S G+ Y S DC W I P V L F+ F E +
Sbjct: 2111 CGGAMSDFSGV--ILSPGFPGN--YPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIH 2162
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY++V G ++P + ST+ + F +D S +GF YQ
Sbjct: 2163 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ 2217
Score = 36.7 bits (81), Expect = 0.25
Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG ++A +YS Y D Y + DC W + P + + + F + E Y
Sbjct: 2283 CGGNITAMNGT--IYSPG-YPDE-YPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 2334
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
D++ V+ F G + STS +L++F +D
Sbjct: 2335 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD 2376
Score = 36.3 bits (80), Expect = 0.33
Identities = 20/93 (21%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ +C W I P +++ ++F E +D + + ++ G +
Sbjct: 1959 YDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLDFYDGGDNNAPRLGSYSGTTI 2014
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y +
Sbjct: 2015 PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 2047
Score = 34.7 bits (76), Expect = 1.0
Identities = 26/97 (26%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXX--XXXXTFCG 560
Y+S A C W I A N +++ F F+LE YD + + G
Sbjct: 568 YDSNAQCVWVITAVNTNKVIQINFEEFDLE----IGYDTLTIGDGGEVGDPRTVLQVLTG 623
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVS S + + +TD+S+ GF +Y+ ++
Sbjct: 624 SFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIE 660
>AY358174-1|AAQ88541.1| 1169|Homo sapiens CSMD1 protein.
Length = 1169
Score = 157 bits (381), Expect = 1e-37
Identities = 141/478 (29%), Positives = 212/478 (44%), Gaps = 64/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 606 AACGGNLTGPA-GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 660
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 661 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 719
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 720 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 779
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 780 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 837
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 838 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 892
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 893 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 952
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I++ F E +
Sbjct: 953 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN--- 1009
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 1010 -WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1066
Score = 154 bits (374), Expect = 8e-37
Identities = 138/473 (29%), Positives = 211/473 (44%), Gaps = 70/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ + G L SPN+P +Y N CI+K+ + LR SF++ DT
Sbjct: 259 AECGASVK-GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT---- 313
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDI-RSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+KV DG S +G F +++ I STSN L + F ++ + GF T+ FD
Sbjct: 314 -LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS-FDL 371
Query: 167 CASIDHGCSHSC--VNTLGGYE-----CACDIGYELHSDGK----------------KCE 203
D G + + G + +C+ GY +H C
Sbjct: 372 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 431
Query: 204 NACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
CGG ++ +G I SP +P Y +C W I A P I+L+F FD E H
Sbjct: 432 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----- 486
Query: 263 CEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + V + +D+L + + G+ALP + S + L +QF SD + +SGF+ +
Sbjct: 487 ---DILKVWDGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 541
Query: 322 IDV-----DECAENNG---GCQHECHNTL-----GGYE--------CA-CHSGFTLHPNK 359
+ D NG G E +T+ GY+ C ++ F P+
Sbjct: 542 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 601
Query: 360 HDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C C ++T P G I SPNYP YP K+C W+ P I LIF F +EP
Sbjct: 602 PTC-IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP--- 657
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+YD + IY+G ++ +G + GS+ P + +S N +++ F+SD SV GF
Sbjct: 658 -SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 709
Score = 146 bits (353), Expect = 3e-34
Identities = 134/470 (28%), Positives = 194/470 (41%), Gaps = 63/470 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I ++G + SP YP Y N C W + ++L F F+ E ++D
Sbjct: 432 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 487
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF--- 164
+KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 488 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 547
Query: 165 -DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KCENA 205
++ +G + G CD GY+L K C A
Sbjct: 548 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 607
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ + Y
Sbjct: 608 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH--IY 665
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 666 EGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 718
Query: 326 ECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTLP-- 374
E + G G + LG C SG+ L P+ C +G D LP
Sbjct: 719 EACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 778
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SPNYP Y A + C++ T P + +F F Q D
Sbjct: 779 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTALND 833
Query: 424 HVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 834 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 883
Score = 107 bits (257), Expect = 1e-22
Identities = 133/483 (27%), Positives = 199/483 (41%), Gaps = 73/483 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGG I+ S G + SP +PD Y PN L C W + V V + FH+F +E+ S
Sbjct: 84 DALCGGYIQGKS-GTVLSPGFPDFY-PNSLNCTWTIEVSHGKGVQMIFHTFHLES----S 137
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S P + G +P I++ + + F SD ++ GF+ TF
Sbjct: 138 HDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF-S 195
Query: 163 EFDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDGK---------------- 200
E+D D G S G +C +GY L K
Sbjct: 196 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 255
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+C CG ++ G GT+ SP+FP Y C+++I I L F L
Sbjct: 256 RCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQL------- 308
Query: 261 QECEYDSVTVHSKLGADVLRRH-GAFCGTALPPPV-TSDGSVLRVQFTSDGSVHRSGFAA 318
E D++ V+ G D R G F L + S + L ++F ++GS GF
Sbjct: 309 --FEGDTLKVYD--GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQL 364
Query: 319 VY-YIDVDECAE----NNG-GCQHECHNTLGGYECACHSGFTLH-PNKHDCKEGGCK-HD 370
Y D+ +C + N G + E H T +C+ G+ +H N C G + D
Sbjct: 365 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 424
Query: 371 VTLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP 416
LP G I SP YPA Y C W PG I L F VF+
Sbjct: 425 KPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD--- 481
Query: 417 HQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
E A+D + ++DG L + GS LP + ++ N + + F SD + + GF
Sbjct: 482 -TEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQF 540
Query: 477 STA 479
ST+
Sbjct: 541 STS 543
Score = 101 bits (241), Expect = 1e-20
Identities = 107/404 (26%), Positives = 166/404 (41%), Gaps = 64/404 (15%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS-Y 106
A CGG S G + SPNYP +Y ++C++ ++VP+++ V +F F+ +D +
Sbjct: 780 APCGGQY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 838
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KE 163
D + + S L G G +P +TSN++L+ F + S GF + +
Sbjct: 839 DGTHAQA--RLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQAVPRT 893
Query: 164 FD-ECASID---HGCSHSCVNTLGGY-ECACDIGYELH-SDGKKCENA------------ 205
D +C+S+ +G + G C+ GY L S C++
Sbjct: 894 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 953
Query: 206 -----CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C G GTI SP +PE Y NC+W+I+ I + F E N
Sbjct: 954 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 1009
Query: 261 QECEYDSVTVHSKLGADVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ +H G DV R G+F GT +P + S + L + F SD SV +GF
Sbjct: 1010 ----WDSLEIHD--GGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE 1063
Query: 320 YY-IDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEGG------- 366
Y + + C E +N + + C G+TL H C G
Sbjct: 1064 YKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1123
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGH 403
C ++ G I SP +P +YP DC W+ S G+
Sbjct: 1124 SPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 1167
Score = 94.7 bits (225), Expect = 9e-19
Identities = 77/311 (24%), Positives = 135/311 (43%), Gaps = 33/311 (10%)
Query: 189 CDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF 248
C+ ++ + C+ CGG + G +GT+ SP FP+ YP NC W I + + F
Sbjct: 70 CERNHQWNHALPSCDALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIF 129
Query: 249 THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
F LE +H +Y +T V R G+ + + + + +++F SD
Sbjct: 130 HTFHLESSH------DYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFISD 182
Query: 309 GSVHRSGFAAVY-YIDVDECAENNGGC---QHECHNTLG-GYECACHSGFTLH-PNKHDC 362
S+ GF + D++ C + + H +G +C G+ L K C
Sbjct: 183 FSISYEGFNITFSEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTC 242
Query: 363 KEGG--------------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLI 408
GG C V GT+ SPN+P+ Y +C+++ T G I L
Sbjct: 243 LGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLR 302
Query: 409 FNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSV 467
F+L D + +YDG + + LG F ++L L++ ++ N +++ F ++GS
Sbjct: 303 TRSFQL-----FEGDTLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSD 357
Query: 468 QRKGFLATHST 478
+GF T+++
Sbjct: 358 TDQGFQLTYTS 368
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ V ++ + Y +CDW ++ + + L F +F +E
Sbjct: 607 ACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 658
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 659 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 714
Score = 39.1 bits (87), Expect = 0.047
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ C W IEA + L F+ F+ E +D ++V+ + G +
Sbjct: 455 YDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDILKVWDGPVDSDILLKEWSGSAL 510
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P +I ST +L ++F +D + GFS +
Sbjct: 511 PEDIHSTFNSLTLQFDSDFFISKSGFSIQF 540
Score = 37.5 bits (83), Expect = 0.14
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I +++ ++F E+ +D +++ +F G +
Sbjct: 979 YGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLEIHDGGDVTAPRLGSFSGTTV 1034
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y+ V
Sbjct: 1035 PALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1067
>AK126936-1|BAC86754.1| 783|Homo sapiens protein ( Homo sapiens
cDNA FLJ44989 fis, clone BRAWH3008167, highly similar
to Homo sapiens CUB and Sushi multiple domains 1
(CSMD1). ).
Length = 783
Score = 157 bits (381), Expect = 1e-37
Identities = 141/478 (29%), Positives = 212/478 (44%), Gaps = 64/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 123 AACGGNLTGPA-GIILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 177
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 178 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 236
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 237 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 296
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 297 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 354
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 355 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 409
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 410 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 469
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I++ F E +
Sbjct: 470 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN--- 526
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 527 -WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 583
Score = 125 bits (301), Expect = 6e-28
Identities = 126/482 (26%), Positives = 202/482 (41%), Gaps = 68/482 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS-Y 106
A CGG S G + SPNYP +Y ++C++ ++VP+++ V +F F+ +D +
Sbjct: 297 APCGGQY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 355
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KE 163
D + + S L G G +P +TSN++L+ F + S GF + +
Sbjct: 356 DGTHAQA--RLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQAVPRT 410
Query: 164 FD-ECASID---HGCSHSCVNTLGGY-ECACDIGYELH-SDGKKCENA------------ 205
D +C+S+ +G + G C+ GY L S C++
Sbjct: 411 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 470
Query: 206 -----CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C G GTI SP +PE Y NC+W+I+ I + F E N
Sbjct: 471 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 526
Query: 261 QECEYDSVTVHSKLGADVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ +H G DV R G+F GT +P + S + L + F SD SV +GF
Sbjct: 527 ----WDSLEIHD--GGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE 580
Query: 320 YY-IDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEGG------- 366
Y + + C E +N + + C G+TL H C G
Sbjct: 581 YKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 640
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C ++ G I SP +P +YP DC W+ S G+ + F F E +
Sbjct: 641 SPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEAN-- 698
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
+D + I +G +G F G+ LP ++++ ++ ++ F SD S R+GF +
Sbjct: 699 --HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETFIHFYSDHSQNRQGFKLAYQGG 756
Query: 480 CG 481
G
Sbjct: 757 SG 758
Score = 115 bits (276), Expect = 6e-25
Identities = 116/413 (28%), Positives = 169/413 (40%), Gaps = 59/413 (14%)
Query: 105 SYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
++D +KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 2 AHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSI 61
Query: 165 ----DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KC 202
++ +G + G CD GY+L K C
Sbjct: 62 AATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 121
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ +
Sbjct: 122 IAACGGNLTGPAGIILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH- 180
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
Y+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 181 -IYEGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKE 232
Query: 323 DVDECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTL 373
E + G G + LG C SG+ L P+ C +G D L
Sbjct: 233 KPREACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVL 292
Query: 374 P-------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
P G + SPNYP Y A + C++ T P + +F F Q
Sbjct: 293 PSCNAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTA 347
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
D ++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 348 LNDLAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 400
Score = 48.4 bits (110), Expect = 8e-05
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 465 GSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
G+V+R + + A CGG LS V + S G +Y + DC W I P +
Sbjct: 632 GTVRRWNYPSPLCIATCGGTLSTLGGV--ILSPGFPG--SYPNNLDCTWRISLPIGYGAH 687
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+ FL F E AN +D++++ F G +P ++ST+ + F +D S
Sbjct: 688 IQFLNFSTE--AN--HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETFIHFYSDHS 743
Query: 584 LVFKGFSASYQ 594
+GF +YQ
Sbjct: 744 QNRQGFKLAYQ 754
Score = 46.0 bits (104), Expect = 4e-04
Identities = 26/116 (22%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ + ++ + Y +CDW ++ + + L F +F +E
Sbjct: 124 ACGGNLTGPAGIILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 175
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 176 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 231
Score = 37.5 bits (83), Expect = 0.14
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I +++ ++F E+ +D +++ +F G +
Sbjct: 496 YGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLEIHDGGDVTAPRLGSFSGTTV 551
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y+ V
Sbjct: 552 PALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 584
>AB067477-1|BAB67783.1| 1048|Homo sapiens KIAA1890 protein protein.
Length = 1048
Score = 157 bits (381), Expect = 1e-37
Identities = 141/478 (29%), Positives = 212/478 (44%), Gaps = 64/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 485 AACGGNLTGPA-GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 539
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 540 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 598
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 599 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 658
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 659 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 716
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 717 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 771
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 772 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 831
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I++ F E +
Sbjct: 832 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN--- 888
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+D + I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 889 -WDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 945
Score = 154 bits (374), Expect = 8e-37
Identities = 138/473 (29%), Positives = 211/473 (44%), Gaps = 70/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ + G L SPN+P +Y N CI+K+ + LR SF++ DT
Sbjct: 138 AECGASVK-GNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT---- 192
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDI-RSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+KV DG S +G F +++ I STSN L + F ++ + GF T+ FD
Sbjct: 193 -LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTY-TSFDL 250
Query: 167 CASIDHGCSH--SCVNTLGGYE-----CACDIGYELHSDG----------------KKCE 203
D G + + G + +C+ GY +H C
Sbjct: 251 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 310
Query: 204 NACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
CGG ++ +G I SP +P Y +C W I A P I+L+F FD E H
Sbjct: 311 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----- 365
Query: 263 CEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + V + +D+L + + G+ALP + S + L +QF SD + +SGF+ +
Sbjct: 366 ---DILKVWDGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 420
Query: 322 IDV-----DECAENNG---GCQHECHNTL-----GGYE--------CA-CHSGFTLHPNK 359
+ D NG G E +T+ GY+ C ++ F P+
Sbjct: 421 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 480
Query: 360 HDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C C ++T P G I SPNYP YP K+C W+ P I LIF F +EP
Sbjct: 481 PTC-IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP--- 536
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+YD + IY+G ++ +G + GS+ P + +S N +++ F+SD SV GF
Sbjct: 537 -SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 588
Score = 146 bits (353), Expect = 3e-34
Identities = 134/470 (28%), Positives = 194/470 (41%), Gaps = 63/470 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I ++G + SP YP Y N C W + ++L F F+ E ++D
Sbjct: 311 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 366
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF--- 164
+KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 367 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 426
Query: 165 -DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KCENA 205
++ +G + G CD GY+L K C A
Sbjct: 427 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 486
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ + Y
Sbjct: 487 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH--IY 544
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 545 EGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 597
Query: 326 ECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTLP-- 374
E + G G + LG C SG+ L P+ C +G D LP
Sbjct: 598 EACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 657
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SPNYP Y A + C++ T P + +F F Q D
Sbjct: 658 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTALND 712
Query: 424 HVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 713 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 762
Score = 101 bits (241), Expect = 1e-20
Identities = 107/404 (26%), Positives = 166/404 (41%), Gaps = 64/404 (15%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS-Y 106
A CGG S G + SPNYP +Y ++C++ ++VP+++ V +F F+ +D +
Sbjct: 659 APCGGQY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 717
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KE 163
D + + S L G G +P +TSN++L+ F + S GF + +
Sbjct: 718 DGTHAQA--RLLSSLSGSHSGETLP---LATSNQILLRFSAKSGASARGFHFVYQAVPRT 772
Query: 164 FD-ECASID---HGCSHSCVNTLGGY-ECACDIGYELH-SDGKKCENA------------ 205
D +C+S+ +G + G C+ GY L S C++
Sbjct: 773 SDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 832
Query: 206 -----CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C G GTI SP +PE Y NC+W+I+ I + F E N
Sbjct: 833 SCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQN---- 888
Query: 261 QECEYDSVTVHSKLGADVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+DS+ +H G DV R G+F GT +P + S + L + F SD SV +GF
Sbjct: 889 ----WDSLEIHD--GGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE 942
Query: 320 YY-IDVDECAE----NNGGCQHECHNTLGGYECACHSGFTLHPNKH-DCKEGG------- 366
Y + + C E +N + + C G+TL H C G
Sbjct: 943 YKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1002
Query: 367 -------CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGH 403
C ++ G I SP +P +YP DC W+ S G+
Sbjct: 1003 SPLCIATCGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGY 1046
Score = 81.0 bits (191), Expect = 1e-14
Identities = 115/440 (26%), Positives = 175/440 (39%), Gaps = 70/440 (15%)
Query: 89 VALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIF 145
V + FH+F +E+ S+D + + + S P + G +P I++ + + F
Sbjct: 4 VQMIFHTFHLES----SHDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRF 58
Query: 146 ESDSTVQKAGFSATFMKEFDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDG 199
SD ++ GF+ TF E+D D G S G +C +GY L
Sbjct: 59 ISDFSISYEGFNITF-SEYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGAT 117
Query: 200 K----------------KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHR 243
K +C CG ++ G GT+ SP+FP Y C+++I
Sbjct: 118 KLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKG 177
Query: 244 ITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRH-GAFCGTALPPPV-TSDGSVL 301
I L F L E D++ V+ G D R G F L + S + L
Sbjct: 178 IHLRTRSFQL---------FEGDTLKVYD--GKDSSSRPLGTFTKNELLGLILNSTSNHL 226
Query: 302 RVQFTSDGSVHRSGFAAVY-YIDVDECAE----NNG-GCQHECHNTLGGYECACHSGFTL 355
++F ++GS GF Y D+ +C + N G + E H T +C+ G+ +
Sbjct: 227 WLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAM 286
Query: 356 H-PNKHDCKEGGCK-HDVTLP--------------HGTIFSPNYPAAYPARKDCVWQFST 399
H N C G + D LP G I SP YPA Y C W
Sbjct: 287 HGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEA 346
Query: 400 TPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYM 459
PG I L F VF+ E A+D + ++DG L + GS LP + ++ N + +
Sbjct: 347 DPGKTISLHFIVFD----TEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTL 402
Query: 460 VFKSDGSVQRKGFLATHSTA 479
F SD + + GF ST+
Sbjct: 403 QFDSDFFISKSGFSIQFSTS 422
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ V ++ + Y +CDW ++ + + L F +F +E
Sbjct: 486 ACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 537
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 538 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 593
Score = 39.1 bits (87), Expect = 0.047
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ C W IEA + L F+ F+ E +D ++V+ + G +
Sbjct: 334 YDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDILKVWDGPVDSDILLKEWSGSAL 389
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P +I ST +L ++F +D + GFS +
Sbjct: 390 PEDIHSTFNSLTLQFDSDFFISKSGFSIQF 419
Score = 37.5 bits (83), Expect = 0.14
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I +++ ++F E+ +D +++ +F G +
Sbjct: 858 YGNNLNCIWKIIVTEGSGIQIQVISFATEQN----WDSLEIHDGGDVTAPRLGSFSGTTV 913
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P + STS L + F++D S+ GF Y+ V
Sbjct: 914 PALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 946
>AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein.
Length = 2977
Score = 157 bits (380), Expect = 1e-37
Identities = 138/469 (29%), Positives = 201/469 (42%), Gaps = 59/469 (12%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG I G + SP YP+ Y N C+WK++VP+ + ++ SF E++ +D +
Sbjct: 1209 CGG-ILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSL 1263
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
DG ++P +G + G IP + STSN L + F+SD +V AGF + D C
Sbjct: 1264 DFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCP 1323
Query: 169 SIDHGCSHSCVNT---LGGY-ECACDIGYEL--HSD-----GKK---------CENACGG 208
S + +G CD GY L HS G C CGG
Sbjct: 1324 EPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGG 1383
Query: 209 ALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
A+ +G I SP FP YP +C W I P + L F +F E H +Y V
Sbjct: 1384 AMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIH------DYLEV 1437
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDEC 327
S + V+ G G +P + S + F SD S ++ GF VY + C
Sbjct: 1438 RSGSSETSTVI---GRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSC 1494
Query: 328 AE----NNG---GCQHECHNTLG-----GYECACHSGFT-LHPNKHDCK------EGGCK 368
+ NG G T+ GY +S T LH + E C
Sbjct: 1495 PDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG 1554
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIY 428
++T +GTI+SP YP YP +DC W PG+ I + F V + EP YD +T++
Sbjct: 1555 GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVW 1610
Query: 429 DGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
DG + +G F G+ V ++ NQ+ + F SD + L+ H+
Sbjct: 1611 DGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHA 1659
Score = 152 bits (369), Expect = 3e-36
Identities = 134/465 (28%), Positives = 206/465 (44%), Gaps = 66/465 (14%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SP+YP+ Y N CIW + ++ L F+ F++E+ +D + V+DGDS +S
Sbjct: 70 GTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPES 125
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC----------- 167
P++G F G ++P + S S+ L + F++D ++ GF+ T+ +EC
Sbjct: 126 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARR 185
Query: 168 --------ASIDHGCSHSCVNTLGGYECACDI--GYELHSD-GKKCENACGGALYGPNGT 216
+SI C + T G C + G + S KC CGG P+G
Sbjct: 186 FGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGV 245
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
I SP +P Y NC W I A P H I + F F Q E YD + VH G
Sbjct: 246 ILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERF--------QTELNYDVLEVHD--GP 295
Query: 277 DVLR-RHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN- 331
++L G++ GT +P + S + + + FT+D S +GF Y ++ C +
Sbjct: 296 NLLSPLLGSYNGTQVPQFLFSISNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGI 355
Query: 332 --GGCQHECHNTLGG-YECACHSGFTL-HPNKHDCKEGG------------CKHDVTLPH 375
G ++ ++G +C SG+ L H C++ C DV P
Sbjct: 356 PVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPS 415
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GTI SP YP YP +C W T G ++ F+ F LE H +D++ I + S
Sbjct: 416 GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDH----HDYLLITENGSF-T 470
Query: 436 KTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ L GS LP + A + + F SD S+ +GF T S
Sbjct: 471 QPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFS 515
Score = 142 bits (343), Expect = 5e-33
Identities = 130/471 (27%), Positives = 196/471 (41%), Gaps = 66/471 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ G L SPNYP +Y+ N CI+ + V + + +F + D
Sbjct: 579 AECGASA-TNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDV---- 633
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+K+ DG + L+G F G + + STSN+L + F SD+ GF + E
Sbjct: 634 -LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELS 692
Query: 166 ECASI---DHGCSHSCVNTLGGYEC--ACDIGYELHSD-------GKK---------CEN 204
C G S G C+ GY LH G++ C
Sbjct: 693 HCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 752
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G + G I SP +P Y C+W I P + ++L F FD E +H +
Sbjct: 753 ECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRV- 811
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
+D + L ++ G+ +P + S +++ +QF +D + +SGFA +
Sbjct: 812 -WDGPPENDMLLKEI-------SGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSS 863
Query: 324 VDECAENNGGCQHECHNTLG-------------GYECACHSGFTL---------HPNKHD 361
V + G + N G GYE T P+
Sbjct: 864 VATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPV 923
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C ++T G I SPN+P YP +DC W + + I L F F +EP+
Sbjct: 924 CI-APCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---- 978
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD + IYDG ++ +G F SKLP + +S N M++ F+SDGSV GF
Sbjct: 979 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGF 1029
Score = 141 bits (341), Expect = 8e-33
Identities = 129/476 (27%), Positives = 203/476 (42%), Gaps = 65/476 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG S G + SP +P Y+ + C W + + + + F F+ E +YD
Sbjct: 233 APCGGHFSAPS-GVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----LNYD 287
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++V DG ++ SPL+G + G ++P + S SN + ++F +D++ GF + +
Sbjct: 288 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSISNFIYLLFTTDNSRSNNGFKIHYESVTVNT 347
Query: 167 CASID-----HGCSHSCVNTLGG-YECACDIGYEL-HSDGKKCEN-------------AC 206
+ +D HG + ++G +CD GY L H + CE C
Sbjct: 348 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 407
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + GP+GTI SP +PE YP NC W + + NF F LE +H Y E
Sbjct: 408 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 467
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSD--GSV-LRVQFTSDGSVHRSGFAAVYYID 323
S T L R G+ LPP + + G+ +++F SD S+ GF +
Sbjct: 468 SFT-------QPLAR---LTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEY 517
Query: 324 VDECAENNG----GCQHECHNTLGG-YECACHSGFTLH-PNKHDCKEGG----------- 366
E E+ G G + + +G +C SG+ L ++ C GG
Sbjct: 518 NLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 577
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C T G + SPNYP Y +C++ G I + F L D
Sbjct: 578 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-----AQGD 632
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMAS-QNQMYMVFKSDGSVQRKGFLATHST 478
+ IYDG LG F G+ + L ++S NQ+++ F SD +GF +++
Sbjct: 633 VLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTS 688
Score = 132 bits (320), Expect = 3e-30
Identities = 150/596 (25%), Positives = 233/596 (39%), Gaps = 77/596 (12%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + +S+G + SP YP Y N C+W + V V+L+F +F+ E S+D
Sbjct: 752 AECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE----ASHD 807
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++V DG + L+ G IP I ST N + + F++D + K+GF+ F
Sbjct: 808 ILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSV-AT 866
Query: 168 ASIDHGCSHSCVNTLGGYECA------CDIGYELHSDGK-----------------KCEN 204
A D G + G E CD GYEL + + C
Sbjct: 867 ACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 926
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L G +G I SP+FP YP ++C W I + I+L F F +E N Y
Sbjct: 927 PCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN--YDFLYI 984
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
YD +S L G+F + LP + S + + + F SDGSV +GF Y +
Sbjct: 985 YDGPDSNSPL-------IGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKL 1037
Query: 325 DECAENNG--------GCQHECHNT----------LGGYE-CACHSGFTLHPNKH----D 361
E + G G ++ +T L GY C G P +
Sbjct: 1038 RESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPS 1097
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
C C T GT+ SPNYP Y +CV+ + + + + E
Sbjct: 1098 C-HAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFAVPRTSST-QCSSVPEPR 1155
Query: 422 YDHVTIYDGASADVKTLGIF-CGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTAC 480
+ G V + +F C P ++ + + Q L T C
Sbjct: 1156 FGRRI---GNEFAVGSSVLFDCN---PGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPC 1209
Query: 481 GGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYD 540
GG L+ + K Y + Y++ +C W I P +++ ++F E +D
Sbjct: 1210 GGILT---KRKGTILSPGYPE-PYDNNLNCVWKITVPEGAGIQVQVVSFATEH----NWD 1261
Query: 541 YVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+ + ++ G +P + STS L + F++D S+ GF Y +
Sbjct: 1262 SLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI 1317
Score = 118 bits (285), Expect = 5e-26
Identities = 126/499 (25%), Positives = 204/499 (40%), Gaps = 68/499 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + D +G + SP +P +Y + C W +++P + V L+F +F E +D
Sbjct: 1379 AQCGGAMS-DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTET----IHD 1433
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
++VR G S S +IG G +IP + ST+++ + F SD + K GF + +
Sbjct: 1434 YLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQS 1493
Query: 167 CA---------------SIDHGCSHSCVN--TLGGYE---CACDIGYELHSDGKKCENAC 206
C ++ S C TL G C + + +CE C
Sbjct: 1494 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC 1553
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
GG + NGTI SP +P+ YP ++C W + PP + I +NFT + Q E YD
Sbjct: 1554 GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT--------VLQTEPIYD 1605
Query: 267 SVTVHSKLGADVLRRH-GAFCG-TALPPPVTSDGSVL---RVQFTSDG----SVHRSGFA 317
+TV G D G F G TAL ++ +L FT+ G S H
Sbjct: 1606 FITVWD--GPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLR 1663
Query: 318 AVY---------YIDVDECAENNGGCQHEC---HNTLGGYECACHSGFTLHPNKHD--CK 363
+ D+ E +++C +G C G L + C+
Sbjct: 1664 VCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ 1723
Query: 364 EGGCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
+++ L G I SP YP +YP + C W S G+ I + F+ E +
Sbjct: 1724 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----F 1779
Query: 423 DHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
D + +YDG + L G + ++ +++++ + +D +KGF +
Sbjct: 1780 DVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY---IA 1836
Query: 482 GYLSATEEVKHLYSHARYG 500
Y S E H Y ++ G
Sbjct: 1837 FYCSTPESPPHGYIISQTG 1855
Score = 107 bits (257), Expect = 1e-22
Identities = 84/293 (28%), Positives = 126/293 (43%), Gaps = 35/293 (11%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C C P GT+ SP +PE Y NC+W I++ P RI L+F FDLE +
Sbjct: 57 CIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLA 116
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY- 320
+ DS + +L G F G +P +TS+ +LR++F +D S+ GF Y
Sbjct: 117 VKDGDSPE------SPIL---GTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYN 167
Query: 321 YIDVDECAENN---GGCQHECHNTLG-GYECACHSGF--TLHPNKHDC------------ 362
+EC + + + LG C GF T C
Sbjct: 168 TFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGL 227
Query: 363 --KEGG-CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
K G C + P G I SP +P Y +C W PGH IK+ F F+ E +
Sbjct: 228 IPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN-- 285
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
YD + ++DG + LG + G+++P + + N +Y++F +D S GF
Sbjct: 286 --YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSISNFIYLLFTTDNSRSNNGF 336
Score = 97.9 bits (233), Expect = 1e-19
Identities = 80/291 (27%), Positives = 125/291 (42%), Gaps = 33/291 (11%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C CGG L GTI SP +PE Y NC+W+I P I + F E N
Sbjct: 1205 CIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----- 1259
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY- 320
+DS+ + G + R G++ GT +P + S + L + F SD SV +GF Y
Sbjct: 1260 ---WDSLDFYDG-GDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYT 1315
Query: 321 YIDVDECAE---NNGGCQHECHNTLGG-YECACHSGFTLHPNKH-DCKEGGCKH-DVTLP 374
I +D C E + G + +G C G++L + H C G + + +P
Sbjct: 1316 AIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIP 1375
Query: 375 -------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
G I SP +P YP+ DC W + G + L F F E
Sbjct: 1376 ICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFS----TETI 1431
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+D++ + G+S +G G ++P + ++ ++ + F SD S ++GF
Sbjct: 1432 HDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGF 1482
Score = 94.7 bits (225), Expect = 9e-19
Identities = 87/303 (28%), Positives = 132/303 (43%), Gaps = 47/303 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA+CGG+I NG + SP YPD+Y + C W + VP + + F + E Y
Sbjct: 1550 EALCGGNITA-MNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IY 1604
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF---------- 156
D + V DG +SP IG F G+ + STSN++L+ F SD T +GF
Sbjct: 1605 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQL 1662
Query: 157 ----------SATFMKEFDECASIDHGCSHSCV---NTLGGYECACDIGYELHSDGKK-- 201
+A + E DE I + C+ +G C +G L DG
Sbjct: 1663 RVCQPPPPVPNAEILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV 1721
Query: 202 CENAC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
C+ C G I SP +P+ YP L+ C W I + IT+ F F +
Sbjct: 1722 CQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF-------F 1773
Query: 260 QQECEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA 317
Q E E+D + V+ + + VL +A +TS+G + +Q+++D ++ GF
Sbjct: 1774 QTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAF--NITSNGHEVFLQWSADHGNNKKGFR 1831
Query: 318 AVY 320
Y
Sbjct: 1832 IRY 1834
Score = 81.0 bits (191), Expect = 1e-14
Identities = 38/112 (33%), Positives = 64/112 (57%), Gaps = 4/112 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P GT+ SP+YP Y +C+W + PG RI L FN F+LE +D +
Sbjct: 61 CLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLA 116
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ DG S + LG F G+++P + ++ + + + F++D S+ +GF T++T
Sbjct: 117 VKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNT 168
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/135 (32%), Positives = 67/135 (49%), Gaps = 7/135 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T GTI SP YP Y +CVW+ + G I++ F E + +D +
Sbjct: 1209 CGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN----WDSLD 1264
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
YDG + LG + G+ +PHL+ ++ N +Y+ F+SD SV GF + TA G L +
Sbjct: 1265 FYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEY-TAIG--LDS 1321
Query: 487 TEEVKHLYSHARYGD 501
E + S + GD
Sbjct: 1322 CPEPQTPSSGIKIGD 1336
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ +C ++ +DS G + SP YPD Y ++C W +SV + Y + + F+ E
Sbjct: 1723 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----E 1778
Query: 106 YDKVKVRDGDSMDSP-LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+D ++V DG ++ SP LI + + +I S +++ + + +D K GF ++ +
Sbjct: 1779 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 1838
Query: 165 DECASIDHGCSHSCVNTLGG-----YECACDIGYELHSDGKKCENACGGALYG 212
C++ + ++ GG ACD G+ L K C + YG
Sbjct: 1839 --CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVG---KSSAVCRKSSYG 1886
Score = 58.0 bits (134), Expect = 1e-07
Identities = 39/133 (29%), Positives = 59/133 (44%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG V G + CGG+ SA V + S G Y+ +C+W IEA H +K
Sbjct: 219 DGKVMWSGLIPKCGAPCGGHFSAPSGV--ILSPGWPG--YYKDSLNCEWVIEAEPGHSIK 274
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V ++ G ++P + S S + + F TD+S
Sbjct: 275 ITFERFQTE----LNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSISNFIYLLFTTDNS 330
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 331 RSNNGFKIHYESV 343
Score = 44.4 bits (100), Expect = 0.001
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L+F F+LE + +D++ V TF G ++
Sbjct: 81 YGNNLNCIWTIISDPGSRIHLSFNDFDLESQ----FDFLAVKDGDSPESPILGTFTGAEV 136
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P + S S L + F+ D S+ +GF+ +Y
Sbjct: 137 PSHLTSNSHILRLEFQADHSMSGRGFNITY 166
Score = 42.3 bits (95), Expect = 0.005
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG +S V + S G+ Y S DC W I P V L F+ F E +
Sbjct: 1381 CGGAMSDFSGV--ILSPGFPGN--YPSSLDCTWTINLPIGFGVHLQFVNFSTE----TIH 1432
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY++V G ++P + ST+ + F +D S +GF YQ
Sbjct: 1433 DYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQ 1487
Score = 36.7 bits (81), Expect = 0.25
Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 8/102 (7%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG ++A +YS Y D Y + DC W + P + + + F + E Y
Sbjct: 1553 CGGNITAMNGT--IYSPG-YPDE-YPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----Y 1604
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
D++ V+ F G + STS +L++F +D
Sbjct: 1605 DFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSD 1646
>AB007617-1|BAA89206.1| 699|Homo sapiens MASP/P100 protein.
Length = 699
Score = 157 bits (380), Expect = 1e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAA 297
Score = 149 bits (362), Expect = 2e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNECPE 303
Score = 74.9 bits (176), Expect = 8e-13
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 46.4 bits (105), Expect = 3e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYR 295
>D61695-1|BAA34864.1| 699|Homo sapiens mannose-binding protein
associated serin protease protein.
Length = 699
Score = 155 bits (377), Expect = 3e-37
Identities = 97/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F+++ H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 90/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD++ + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 32/124 (25%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++++H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F+++ E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYR 295
>D28593-1|BAA05928.1| 699|Homo sapiens MASP protein.
Length = 699
Score = 155 bits (377), Expect = 3e-37
Identities = 97/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F+++ H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 90/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD++ + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 32/124 (25%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++++H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F+++ E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIQDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSAENRGWRLSYR 295
>D17525-1|BAA04477.1| 699|Homo sapiens precursor of P100 serine
protease of Ra-reactive factor protein.
Length = 699
Score = 155 bits (377), Expect = 3e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYR 295
>BC106946-1|AAI06947.1| 728|Homo sapiens mannan-binding lectin
serine peptidase 1 (C4/C2 activating component of
Ra-reac protein.
Length = 728
Score = 155 bits (377), Expect = 3e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYR 295
>BC106945-1|AAI06946.1| 728|Homo sapiens mannan-binding lectin
serine peptidase 1 (C4/C2 activating component of
Ra-reac protein.
Length = 728
Score = 155 bits (377), Expect = 3e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYR 295
>BC039724-1|AAH39724.1| 488|Homo sapiens MASP1 protein protein.
Length = 488
Score = 155 bits (377), Expect = 3e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 137 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 191
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 192 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 247
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 248 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 307
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 308 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 363
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 364 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAA 405
Score = 148 bits (359), Expect = 5e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 137 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 193
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 194 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 252
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 253 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 312
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 313 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 365
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 366 PFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPE 411
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 293 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 352
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 353 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE 408
Query: 167 CASI 170
C +
Sbjct: 409 CPEL 412
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 146 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 201
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 202 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 246
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 312 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 367
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 368 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYR 403
>AF284421-1|AAK84071.1| 728|Homo sapiens complement factor MASP-3
protein.
Length = 728
Score = 155 bits (377), Expect = 3e-37
Identities = 98/282 (34%), Positives = 138/282 (48%), Gaps = 30/282 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP +P+ YP W I P RI L F HF+LE +++ CEYD V V ++
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYL----CEYDYVKVETE- 83
Query: 275 GADVLRRHGAFCG-----TALPPP---VTSDGSVLRVQFTSDGSVHR--SGFAAVYY-ID 323
VL FCG T P V S GS + + F SD S +GF A Y +D
Sbjct: 84 -DQVL---ATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVD 139
Query: 324 VDECAENNG---GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
VDEC E C H CHN +GGY C+C G+ LH + C+ + T G I S
Sbjct: 140 VDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITS 199
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P++P YP +C++ G + L F ++F++E H E C YD++ I G K
Sbjct: 200 PDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KV 255
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA 479
LG FCG K P + + + ++F SD S + +G+ ++ A
Sbjct: 256 LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAA 297
Score = 148 bits (359), Expect = 5e-35
Identities = 91/286 (31%), Positives = 134/286 (46%), Gaps = 27/286 (9%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G ++SP YPD Y + W ++VP +++ L F F +E+ C YD VKV D
Sbjct: 29 GQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQ--- 85
Query: 120 PLIGMFCGHKIPPD--------IRSTSNKLLVIFESDSTVQK--AGFSATFMK-EFDECA 168
++ FCG + + S + + + F SD + ++ GF A +M + DEC
Sbjct: 86 -VLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 169 SIDH---GCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPE 224
+ C H C N +GGY C+C GY LH+D + C C L+ G ITSP FP
Sbjct: 145 EREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPN 204
Query: 225 LYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
YP CL+ I + L F FD+E + + C YD + + K+G VL G
Sbjct: 205 PYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP--EVPCPYDYIKI--KVGPKVL---G 257
Query: 284 AFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
FCG P P+++ + + F SD S G+ Y +EC E
Sbjct: 258 PFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPE 303
Score = 73.7 bits (173), Expect = 2e-12
Identities = 33/124 (26%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDT--CSY 106
C ++ G + SP++P+ Y + C++ + + + + V L+F F++E+H C Y
Sbjct: 185 CSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPY 244
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
D +K++ G + +G FCG K P I + S+ +L++F SD++ + G+ ++ +E
Sbjct: 245 DYIKIKVGPKV----LGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE 300
Query: 167 CASI 170
C +
Sbjct: 301 CPEL 304
Score = 47.2 bits (107), Expect = 2e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 14/105 (13%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG- 560
++Y S ++ WNI P +KL F+ F LE C YDYV+V TFCG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKV----ETEDQVLATFCGR 93
Query: 561 ----IKMPP--EIV-STSEALLVRFRTDDSLV--FKGFSASYQMV 596
+ P E+V S + + FR+D S F GF A Y V
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAV 138
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELER--EANCRYDYVQVFXXXXXXXXXXXTF 558
N Y ++C + IE V L F F++E E C YDY+++ F
Sbjct: 204 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKI----KVGPKVLGPF 259
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
CG K P I + S ++L+ F +D+S +G+ SY+
Sbjct: 260 CGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYR 295
>AK055132-1|BAB70859.1| 579|Homo sapiens protein ( Homo sapiens
cDNA FLJ30570 fis, clone BRAWH2005998, weakly similar to
BONE MORPHOGENETIC PROTEIN 1 PRECURSOR (EC 3.4.24.-). ).
Length = 579
Score = 153 bits (370), Expect = 2e-36
Identities = 89/281 (31%), Positives = 136/281 (48%), Gaps = 17/281 (6%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
++ CGG + G SPNYPD Y PN C+W + V D+ + L+ + +E+ +C +
Sbjct: 141 QSTCGGLLS-GPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLF 199
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF-- 164
D++++ + PL+ + CG PP + + ++ LLV+F SDS+V+ GF A +
Sbjct: 200 DRLEL--SPEPEGPLLRV-CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Query: 165 -DECASIDHGCSH-SCV---NTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITS 219
CA + C C+ + G+ D E + K + CGG L G GT ++
Sbjct: 257 RGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAK--FSGCGGNLTGLQGTFST 314
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVL 279
PS+ + YP C W I P H I L F +F LE Q EC++D V V+ +
Sbjct: 315 PSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEA----QDECKFDYVEVYETSSSGAF 370
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G FCG PP + S L V F +D + GF+A Y
Sbjct: 371 SLLGRFCGAEPPPHLVSSHHELSVLFRTDHGISSGGFSATY 411
Score = 145 bits (352), Expect = 4e-34
Identities = 88/283 (31%), Positives = 136/283 (48%), Gaps = 21/283 (7%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
++ CGG L GP G +SP++P+ YPP +C+W I H I L +E
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIES----VAS 196
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C +D + + + +LR CG PP + ++ S L V F SD SV GF A Y
Sbjct: 197 CLFDRLELSPEPEGPLLR----VCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWY-- 250
Query: 323 DVDECAENNGGCQHE---CHNTLGGYECACHSGFTLHPNKHD-----CKEGGCKHDVTLP 374
A G C H+ C + + GF + D K GC ++T
Sbjct: 251 --QAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGL 308
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT +P+Y YP + C W S GH I+L F+ F LE EC +D+V +Y+ +S+
Sbjct: 309 QGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG 368
Query: 435 V-KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
LG FCG++ P +++S +++ ++F++D + GF AT+
Sbjct: 369 AFSLLGRFCGAEPPPHLVSSHHELSVLFRTDHGISSGGFSATY 411
Score = 94.7 bits (225), Expect = 9e-19
Identities = 53/166 (31%), Positives = 87/166 (52%), Gaps = 7/166 (4%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ G +P+Y Y LC W +SVP + + L+FH+F +E D C +D V
Sbjct: 301 CGGNL-TGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYV 359
Query: 110 KVRDGDSMDS-PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+V + S + L+G FCG + PP + S+ ++L V+F +D + GFSAT++ F+
Sbjct: 360 EVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELSVLFRTDHGISSGGFSATYL-AFNATE 418
Query: 169 SIDHGCSHSC-VNTLGGYECACDIGYELHSDGKKCENACGGALYGP 213
+ SC G + CD+ + +DG ++ C G L+ P
Sbjct: 419 NPCGPSELSCQAGGCKGVQWMCDMWRDC-TDGS--DDNCSGPLFPP 461
Score = 76.2 bits (179), Expect = 3e-13
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
+ CGG L+ + S+ + Y + C W+I P H ++L F F LE + C
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQ----YPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 354
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
++DYV+V+ FCG + PP +VS+ L V FRTD + GFSA+Y
Sbjct: 355 KFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELSVLFRTDHGISSGGFSATY 411
Score = 58.4 bits (135), Expect = 7e-08
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 3/109 (2%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P G SPNYP YP CVW H I+L +E C +D + +
Sbjct: 151 PRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPEG 210
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ + CG P + + + + +VF SD SV+ GF A + G
Sbjct: 211 PLLRV---CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G + + CGG LS + +S Y D Y C W+I+ +H ++L
Sbjct: 132 QESGVSPSPQSTCGGLLSGP---RGFFSSPNYPD-PYPPNTHCVWHIQVATDHAIQLKIE 187
Query: 528 TFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFK 587
+E A+C +D +++ CG PP + + + LLV F +D S+
Sbjct: 188 ALSIESVASCLFDRLEL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 244
Query: 588 GFSASYQMVKP 598
GF A YQ + P
Sbjct: 245 GFHAWYQAMAP 255
>AJ862823-1|CAH93521.1| 578|Homo sapiens membrane frizzled related
protein protein.
Length = 578
Score = 153 bits (370), Expect = 2e-36
Identities = 89/281 (31%), Positives = 136/281 (48%), Gaps = 17/281 (6%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
++ CGG + G SPNYPD Y PN C+W + V D+ + L+ + +E+ +C +
Sbjct: 140 QSTCGGLLS-GPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLF 198
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF-- 164
D++++ + PL+ + CG PP + + ++ LLV+F SDS+V+ GF A +
Sbjct: 199 DRLEL--SPEPEGPLLRV-CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 255
Query: 165 -DECASIDHGCSH-SCV---NTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITS 219
CA + C C+ + G+ D E + K + CGG L G GT ++
Sbjct: 256 RGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAK--FSGCGGNLTGLQGTFST 313
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVL 279
PS+ + YP C W I P H I L F +F LE Q EC++D V V+ +
Sbjct: 314 PSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEA----QDECKFDYVEVYETSSSGAF 369
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G FCG PP + S L V F +D + GF+A Y
Sbjct: 370 SLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 410
Score = 145 bits (352), Expect = 4e-34
Identities = 88/283 (31%), Positives = 136/283 (48%), Gaps = 21/283 (7%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
++ CGG L GP G +SP++P+ YPP +C+W I H I L +E
Sbjct: 140 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIES----VAS 195
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C +D + + + +LR CG PP + ++ S L V F SD SV GF A Y
Sbjct: 196 CLFDRLELSPEPEGPLLR----VCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWY-- 249
Query: 323 DVDECAENNGGCQHE---CHNTLGGYECACHSGFTLHPNKHD-----CKEGGCKHDVTLP 374
A G C H+ C + + GF + D K GC ++T
Sbjct: 250 --QAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGL 307
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT +P+Y YP + C W S GH I+L F+ F LE EC +D+V +Y+ +S+
Sbjct: 308 QGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG 367
Query: 435 V-KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
LG FCG++ P +++S +++ ++F++D + GF AT+
Sbjct: 368 AFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 410
Score = 95.1 bits (226), Expect = 7e-19
Identities = 53/166 (31%), Positives = 87/166 (52%), Gaps = 7/166 (4%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ G +P+Y Y LC W +SVP + + L+FH+F +E D C +D V
Sbjct: 300 CGGNL-TGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYV 358
Query: 110 KVRDGDSMDS-PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+V + S + L+G FCG + PP + S+ ++L V+F +D + GFSAT++ F+
Sbjct: 359 EVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYL-AFNATE 417
Query: 169 SIDHGCSHSC-VNTLGGYECACDIGYELHSDGKKCENACGGALYGP 213
+ SC G + CD+ + +DG ++ C G L+ P
Sbjct: 418 NPCGPSELSCQAGGCKGVQWMCDMWRDC-TDGS--DDNCSGPLFPP 460
Score = 76.6 bits (180), Expect = 3e-13
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
+ CGG L+ + S+ + Y + C W+I P H ++L F F LE + C
Sbjct: 298 SGCGGNLTGLQGTFSTPSYLQQ----YPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 353
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
++DYV+V+ FCG + PP +VS+ L V FRTD + GFSA+Y
Sbjct: 354 KFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 410
Score = 58.4 bits (135), Expect = 7e-08
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 3/109 (2%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P G SPNYP YP CVW H I+L +E C +D + +
Sbjct: 150 PRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPEG 209
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ + CG P + + + + +VF SD SV+ GF A + G
Sbjct: 210 PLLRV---CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 255
Score = 54.8 bits (126), Expect = 9e-07
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G + + CGG LS + +S Y D Y C W+I+ +H ++L
Sbjct: 131 QESGMSPSPQSTCGGLLSGP---RGFFSSPNYPD-PYPPNTHCVWHIQVATDHAIQLKIE 186
Query: 528 TFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFK 587
+E A+C +D +++ CG PP + + + LLV F +D S+
Sbjct: 187 ALSIESVASCLFDRLEL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 243
Query: 588 GFSASYQMVKP 598
GF A YQ + P
Sbjct: 244 GFHAWYQAMAP 254
>AB055505-1|BAB39771.1| 579|Homo sapiens membrane-type
frizzled-related protein MFRP protein.
Length = 579
Score = 153 bits (370), Expect = 2e-36
Identities = 89/281 (31%), Positives = 136/281 (48%), Gaps = 17/281 (6%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
++ CGG + G SPNYPD Y PN C+W + V D+ + L+ + +E+ +C +
Sbjct: 141 QSTCGGLLS-GPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLF 199
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF-- 164
D++++ + PL+ + CG PP + + ++ LLV+F SDS+V+ GF A +
Sbjct: 200 DRLEL--SPEPEGPLLRV-CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Query: 165 -DECASIDHGCSH-SCV---NTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITS 219
CA + C C+ + G+ D E + K + CGG L G GT ++
Sbjct: 257 RGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAK--FSGCGGNLTGLQGTFST 314
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVL 279
PS+ + YP C W I P H I L F +F LE Q EC++D V V+ +
Sbjct: 315 PSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEA----QDECKFDYVEVYETSSSGAF 370
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G FCG PP + S L V F +D + GF+A Y
Sbjct: 371 SLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 145 bits (352), Expect = 4e-34
Identities = 88/283 (31%), Positives = 136/283 (48%), Gaps = 21/283 (7%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
++ CGG L GP G +SP++P+ YPP +C+W I H I L +E
Sbjct: 141 QSTCGGLLSGPRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIES----VAS 196
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C +D + + + +LR CG PP + ++ S L V F SD SV GF A Y
Sbjct: 197 CLFDRLELSPEPEGPLLR----VCGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWY-- 250
Query: 323 DVDECAENNGGCQHE---CHNTLGGYECACHSGFTLHPNKHD-----CKEGGCKHDVTLP 374
A G C H+ C + + GF + D K GC ++T
Sbjct: 251 --QAMAPGRGSCAHDEFRCDQLICLLPDSVCDGFANCADGSDETNCSAKFSGCGGNLTGL 308
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT +P+Y YP + C W S GH I+L F+ F LE EC +D+V +Y+ +S+
Sbjct: 309 QGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYVEVYETSSSG 368
Query: 435 V-KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
LG FCG++ P +++S +++ ++F++D + GF AT+
Sbjct: 369 AFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 95.1 bits (226), Expect = 7e-19
Identities = 53/166 (31%), Positives = 87/166 (52%), Gaps = 7/166 (4%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ G +P+Y Y LC W +SVP + + L+FH+F +E D C +D V
Sbjct: 301 CGGNL-TGLQGTFSTPSYLQQYPHQLLCTWHISVPAGHSIELQFHNFSLEAQDECKFDYV 359
Query: 110 KVRDGDSMDS-PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+V + S + L+G FCG + PP + S+ ++L V+F +D + GFSAT++ F+
Sbjct: 360 EVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATYL-AFNATE 418
Query: 169 SIDHGCSHSC-VNTLGGYECACDIGYELHSDGKKCENACGGALYGP 213
+ SC G + CD+ + +DG ++ C G L+ P
Sbjct: 419 NPCGPSELSCQAGGCKGVQWMCDMWRDC-TDGS--DDNCSGPLFPP 461
Score = 76.6 bits (180), Expect = 3e-13
Identities = 39/117 (33%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
+ CGG L+ + S+ + Y + C W+I P H ++L F F LE + C
Sbjct: 299 SGCGGNLTGLQGTFSTPSYLQQ----YPHQLLCTWHISVPAGHSIELQFHNFSLEAQDEC 354
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
++DYV+V+ FCG + PP +VS+ L V FRTD + GFSA+Y
Sbjct: 355 KFDYVEVYETSSSGAFSLLGRFCGAEPPPHLVSSHHELAVLFRTDHGISSGGFSATY 411
Score = 58.4 bits (135), Expect = 7e-08
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 3/109 (2%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P G SPNYP YP CVW H I+L +E C +D + +
Sbjct: 151 PRGFFSSPNYPDPYPPNTHCVWHIQVATDHAIQLKIEALSIESVASCLFDRLELSPEPEG 210
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ + CG P + + + + +VF SD SV+ GF A + G
Sbjct: 211 PLLRV---CGRVPPPTLNTNASHLLVVFVSDSSVEGFGFHAWYQAMAPG 256
Score = 54.4 bits (125), Expect = 1e-06
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G + + CGG LS + +S Y D Y C W+I+ +H ++L
Sbjct: 132 QESGVSPSPQSTCGGLLSGP---RGFFSSPNYPD-PYPPNTHCVWHIQVATDHAIQLKIE 187
Query: 528 TFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFK 587
+E A+C +D +++ CG PP + + + LLV F +D S+
Sbjct: 188 ALSIESVASCLFDRLEL---SPEPEGPLLRVCGRVPPPTLNTNASHLLVVFVSDSSVEGF 244
Query: 588 GFSASYQMVKP 598
GF A YQ + P
Sbjct: 245 GFHAWYQAMAP 255
>AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple
domains protein 1 short form protein.
Length = 3389
Score = 152 bits (368), Expect = 4e-36
Identities = 137/473 (28%), Positives = 210/473 (44%), Gaps = 70/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ + G L SPN+P +Y CI+K+ + LR SF++ DT
Sbjct: 1103 AECGASVK-GNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQLFEGDT---- 1157
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDI-RSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+KV DG S +G F +++ I STSN L + F ++ + GF T+ FD
Sbjct: 1158 -LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS-FDL 1215
Query: 167 CASIDHGCSHSC--VNTLGGYE-----CACDIGYELHSDGK----------------KCE 203
D G + + G + +C+ GY +H C
Sbjct: 1216 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 204 NACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
CGG ++ +G I SP +P Y +C W I A P I+L+F FD E H
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----- 1330
Query: 263 CEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + V + +D+L + + G+ALP + S + L +QF SD + +SGF+ +
Sbjct: 1331 ---DILKVWDGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 1385
Query: 322 IDV-----DECAENNG---GCQHECHNTL-----GGYE--------CA-CHSGFTLHPNK 359
+ D NG G E +T+ GY+ C ++ F P+
Sbjct: 1386 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
Query: 360 HDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C C ++T P G I SPNYP YP K+C W+ P I LIF F +EP
Sbjct: 1446 PTC-IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP--- 1501
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+YD + IY+G ++ +G + GS+ P + +S N +++ F+SD SV GF
Sbjct: 1502 -SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
Score = 150 bits (364), Expect = 1e-35
Identities = 129/462 (27%), Positives = 193/462 (41%), Gaps = 66/462 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
C G+ G + SP YP+ Y N CIWK+ V + + F H
Sbjct: 1803 CSGNF-TQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQDPSDQF---CHGAELGLPF 1858
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
++ DG + +P +G F G +P + STSN+L + F+SD +V AGF + +
Sbjct: 1859 EIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1918
Query: 166 ECA----SIDHGCSHSCVNTLGGYECACDIGYELHS----------------DGKKCENA 205
E A SI G + VN + ++C + GY L C
Sbjct: 1919 EPALPSNSIKIGDRYM-VNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1975
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G I SP FP YP +C W I P + + F +F E NH + E
Sbjct: 1976 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF---LEI 2032
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI-DV 324
+ H+ G F GT LP + S + F SD S +R GF Y ++
Sbjct: 2033 QNGPYHTS------PMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 2086
Query: 325 DECAE----NNGGCQHECHNTLGGYECACHSGFTL--HPNKHDCKEG------------- 365
C + NG + ++ C+ G+ L HP C+ G
Sbjct: 2087 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVL-TCQHGINRNWNYPFPRCD 2145
Query: 366 -GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C ++VT +GTI+SP +P YP KDC+W + PGH + + F + + E D+
Sbjct: 2146 APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDY 2201
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
+ ++DG + LG+F G+ +S NQ+ + F SD S
Sbjct: 2202 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2243
Score = 148 bits (359), Expect = 5e-35
Identities = 139/478 (29%), Positives = 209/478 (43%), Gaps = 63/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 1450 AACGGNLTGPA-GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 1504
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 1563
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 1564 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 1681
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 1682 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 1736
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 1737 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I+ + F
Sbjct: 1797 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQDPSDQFCHGAELGL 1856
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
++ I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 1857 PFE---IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1911
Score = 146 bits (353), Expect = 3e-34
Identities = 134/470 (28%), Positives = 194/470 (41%), Gaps = 63/470 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I ++G + SP YP Y N C W + ++L F F+ E ++D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF--- 164
+KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 165 -DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KCENA 205
++ +G + G CD GY+L K C A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ + Y
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH--IY 1509
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 1510 EGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1562
Query: 326 ECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTLP-- 374
E + G G + LG C SG+ L P+ C +G D LP
Sbjct: 1563 EACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SPNYP Y A + C++ T P + +F F Q D
Sbjct: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTALND 1677
Query: 424 HVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1727
Score = 142 bits (343), Expect = 5e-33
Identities = 136/494 (27%), Positives = 212/494 (42%), Gaps = 74/494 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + G + SP +P Y N C W++S+P Y ++F +F E ++D
Sbjct: 1974 ATCGGTLST-LGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHD 2028
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++++G SP+IG F G +P + ST+++ L+ F SD + + GF + E
Sbjct: 2029 FLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2088
Query: 167 CA---------------SIDHGCSHSCV--NTLGGY---ECACDIGYELHSDGKKCENAC 206
C S+ S C L G+ C I + +C+ C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPC 2148
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
G + NGTI SP FP+ YP LK+C+W I PP H + +NFT + Q E D
Sbjct: 2149 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFT--------LLQTEAVND 2200
Query: 267 SVTVHSKLGADV-LRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--I 322
+ V G D + G F G TAL +S VL ++F SD S GF + +
Sbjct: 2201 YIAVWD--GPDQNSPQLGVFSGNTALETAYSSTNQVL-LKFHSDFS--NGGFFVLNFHAF 2255
Query: 323 DVDECAENNGGCQHECHNTLGGYECA------CHSGFTL-HPNKHDCK-------EGG-- 366
+ +C Q E +E CH G+TL + CK EG
Sbjct: 2256 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2315
Query: 367 -CK-----HDV-TLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C+ ++V T G I SP YP Y + C W P + I + + F+ E
Sbjct: 2316 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ-- 2373
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQ-NQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DG+S L + G+ S+ NQ+Y+ + +D + +KGF ++
Sbjct: 2374 --FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2431
Query: 479 ACGGYLSATEEVKH 492
Y S T +K+
Sbjct: 2432 P---YCSLTHPLKN 2442
Score = 141 bits (341), Expect = 8e-33
Identities = 123/468 (26%), Positives = 194/468 (41%), Gaps = 62/468 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQ-DYQVALRFHSFEVENHDTCSYDK 108
CG ++ S G + SPNYP Y+ N C+W ++ D + L F FE+E YD
Sbjct: 412 CGSNLRGPS-GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDT 466
Query: 109 VKVRDGDSMDSP--LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+ V D + ++ + G +P I S SN++ + +SD ++ GF A + + E
Sbjct: 467 LTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKG 526
Query: 166 EC-------------ASIDHG--CSHSC---VNTLGGYECACDIGYELHSDGKKCENACG 207
C +S HG + C +G C + + C +C
Sbjct: 527 GCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCF 586
Query: 208 GALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS 267
+G I SP++PE Y NC+W I++ P RI L F FD+E ++D
Sbjct: 587 FNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP--------QFDF 638
Query: 268 VTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YIDVDE 326
+ V G + G F G +P + S G ++R++F SD S GF Y +E
Sbjct: 639 LAVKDN-GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNE 697
Query: 327 CAEN----NG---------------GCQHECHNTLGGYECAC--HSGFTLHPNKHDCKEG 365
C + NG C T G C G + + E
Sbjct: 698 CHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEA 757
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
C +T G I P +P Y C W PGH IK+ F+ F+ E + YD +
Sbjct: 758 PCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRFQTEVN----YDTL 813
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
+ DG ++ +G + G++ P ++++ N MY++F +D S GFL
Sbjct: 814 EVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFL 861
Score = 140 bits (339), Expect = 1e-32
Identities = 124/476 (26%), Positives = 205/476 (43%), Gaps = 63/476 (13%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA CGG + S+G + P +P Y+ + C W + + + + F F+ E +Y
Sbjct: 756 EAPCGGHLTA-SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRFQTE----VNY 810
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK---E 163
D ++VRDG + SPLIG + G + P + ST N + ++F +D++ GF + E
Sbjct: 811 DTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
Query: 164 FDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDG--------------KKCE 203
D C +D G H G +CD GY L D C+
Sbjct: 871 SDSC--LDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG + G +GT+ SP FP+ YP NC W I + + F F LE +H
Sbjct: 929 ALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSH------ 982
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YI 322
+Y +T V R G+ + + + + +++F SD S+ GF +
Sbjct: 983 DYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFISDFSISYEGFNITFSEY 1041
Query: 323 DVDECAENNGGC---QHECHNTLG-GYECACHSGFTLH-PNKHDCKEGG----------- 366
D++ C + + H +G +C G+ L K C GG
Sbjct: 1042 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C V GT+ SPN+P+ Y +C+++ T G I L F+L D
Sbjct: 1102 VAECGASVKGNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQL-----FEGD 1156
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATHST 478
+ +YDG + + LG F ++L L++ ++ N +++ F ++GS +GF T+++
Sbjct: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
Score = 136 bits (329), Expect = 2e-31
Identities = 123/466 (26%), Positives = 194/466 (41%), Gaps = 64/466 (13%)
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S+G + SPNYP++Y N C+W + ++ L F+ F+VE +D + V+D
Sbjct: 592 SSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLAVKDNGIS 647
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC--------- 167
D ++G F G+++P + S+ + + + F+SD + GF+ T+ +EC
Sbjct: 648 DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPING 707
Query: 168 ----------ASIDHGCSHSCVNTLGGYECAC---DIGYELHSDGKKCENACGGALYGPN 214
+S+ C V T G C D S +CE CGG L +
Sbjct: 708 RRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASS 767
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I P +P Y +C W I A P H I + F F Q E YD++ V
Sbjct: 768 GVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRF--------QTEVNYDTLEVRDG- 818
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN 331
A G + GT P + S G+ + + FT+D S GF Y ++ D C +
Sbjct: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
Query: 332 GGCQHECHNTLGGYEC----ACHSGFTLHPNKHDCKEGGCKHDVTLP------------- 374
H G +C G+TL ++ E + + LP
Sbjct: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGK 938
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT+ SP +P YP +C W + G +++IF+ F H E ++D++ I + S
Sbjct: 939 SGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTF----HLESSHDYLLITEDGSFS 994
Query: 435 VKTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ + GS LPH + A + F SD S+ +GF T S
Sbjct: 995 -EPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
Score = 119 bits (286), Expect = 4e-26
Identities = 90/295 (30%), Positives = 133/295 (45%), Gaps = 36/295 (12%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFTHFDLEGNHMYQQECE 264
CG L GP+G ITSP++P Y +C+W I P I L F F+LE
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG-------- 463
Query: 265 YDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY- 321
YD++TV K+G D G+++P + S + + + SD S+ GF AVY
Sbjct: 464 YDTLTVGDAGKVG-DTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQE 522
Query: 322 IDVDECAE---------------NNGGCQHEC---HNTLGGYECACHSGFTLHPNKHDCK 363
I+ C + + EC +G C NK C
Sbjct: 523 IEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV 582
Query: 364 EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C + T G I SPNYP Y +CVW + PG RI LIFN F++EP +D
Sbjct: 583 FS-CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FD 637
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ + D +D+ LG F G+++P + +S + + + F+SD S +GF T++T
Sbjct: 638 FLAVKDNGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Score = 114 bits (274), Expect = 1e-24
Identities = 95/293 (32%), Positives = 127/293 (43%), Gaps = 41/293 (13%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + GPNGTI SP FP YP NC W I+ ++RI L+F F LE N + Y
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN--FDILSVY 89
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D L G LP + S GS+L + FT+D +V GF A+Y +
Sbjct: 90 DGQPQQGNLKV-------RLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPS 142
Query: 326 ECAENNG----GCQHECHNTLG---------GYECACHSGFT--LHPNKHD--------C 362
N G G H +G GY H+ T + P C
Sbjct: 143 HTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
Query: 363 K-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
+ EG C + +I SP++P+ Y DC W PG I L+F F+LE
Sbjct: 203 RAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----G 258
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
YD + I G A L G LP V++S+N + + F SD + +RKGF A
Sbjct: 259 YDFLEI-SGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNA 307
Score = 108 bits (259), Expect = 7e-23
Identities = 133/483 (27%), Positives = 199/483 (41%), Gaps = 73/483 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGG I+ S G + SP +PD Y PN L C W + V V + FH+F +E+ S
Sbjct: 928 DALCGGYIQGKS-GTVLSPGFPDFY-PNSLNCTWTIEVSHGKGVQMIFHTFHLES----S 981
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S P + G +P I++ + + F SD ++ GF+ TF
Sbjct: 982 HDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF-S 1039
Query: 163 EFDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDGK---------------- 200
E+D D G S G +C +GY L K
Sbjct: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+C CG ++ G GT+ SP+FP Y C+++I I L F L
Sbjct: 1100 RCVAECGASVKGNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQL------- 1152
Query: 261 QECEYDSVTVHSKLGADVLRRH-GAFCGTALPPPV-TSDGSVLRVQFTSDGSVHRSGFAA 318
E D++ V+ G D R G F L + S + L ++F ++GS GF
Sbjct: 1153 --FEGDTLKVYD--GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQL 1208
Query: 319 VY-YIDVDECAE----NNG-GCQHECHNTLGGYECACHSGFTLH-PNKHDCKEGGCK-HD 370
Y D+ +C + N G + E H T +C+ G+ +H N C G + D
Sbjct: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
Query: 371 VTLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP 416
LP G I SP YPA Y C W PG I L F VF+
Sbjct: 1269 KPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD--- 1325
Query: 417 HQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
E A+D + ++DG L + GS LP + ++ N + + F SD + + GF
Sbjct: 1326 -TEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQF 1384
Query: 477 STA 479
ST+
Sbjct: 1385 STS 1387
Score = 101 bits (242), Expect = 8e-21
Identities = 88/298 (29%), Positives = 124/298 (41%), Gaps = 43/298 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ L FH+F +E + +D +
Sbjct: 32 CGGLVQ-GPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN----FDIL 86
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF-MKEFDECA 168
V DG L G ++P I ST + L + F +D V GF A + + C
Sbjct: 87 SVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
Query: 169 S---IDHGCSHSCVNTLGG---YECACDIGYELH-------SDGK-----------KCEN 204
+ I G H +G Y C E H S G + E
Sbjct: 147 NPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEG 206
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG L G + +I+SP FP Y +C W I+A P I L FT F LE
Sbjct: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG-------- 258
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
YD + + + G LP PV S + LR+ FTSD + R GF A + +
Sbjct: 259 YDFLEISGTEAPSIW-----LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQV 311
Score = 77.8 bits (183), Expect = 1e-13
Identities = 45/118 (38%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNVFELEPHQEC 420
C+ C ++ P G I SPNYP Y CVW +TT P IKL F FELE
Sbjct: 407 CRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER---- 462
Query: 421 AYDHVTIYD-GASADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD +T+ D G D ++ L + GS +P L+++ NQM++ +SD S+ GF A +
Sbjct: 463 GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVY 520
Score = 72.1 bits (169), Expect = 5e-12
Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 29/232 (12%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+A CG ++ NG + SP +PD+Y K CIW ++VP + V + F + E
Sbjct: 2145 DAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVN 2199
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDST---VQKAGFSATFMKE 163
D + V DG +SP +G+F G+ S++N++L+ F SD + F A +K+
Sbjct: 2200 DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKK 2259
Query: 164 F--------------DECASIDHGCSHSC--VNTLGGYE-CACDIGYELHSDGK--KCEN 204
D+ I + C TL G + C + +L +G CE
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2319
Query: 205 AC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
C G +G I SP +P Y + C W I P + IT+ F E
Sbjct: 2320 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2371
Score = 61.7 bits (143), Expect = 8e-09
Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
EA C ++ S+G + SP YP +Y ++ C W + V +Y + + +F+ E
Sbjct: 2318 EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----Q 2373
Query: 106 YDKVKVRDGDSMDSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+D ++V DG S SPL+ + G H + S SN+L + + +D K GF +
Sbjct: 2374 FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2429
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
K C V P+GTI SP +P YP +C W T +RI+L F+ F LE + +
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN----F 83
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
D +++YDG G +LP ++++ + + + F +D +V +GF A +
Sbjct: 84 DILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137
Score = 56.0 bits (129), Expect = 4e-07
Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+ + SP++P +Y+ N C W + +AL F F++E Y
Sbjct: 205 EGACGGTLRGTSSS-ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ ++P I + G +P + S+ N L + F SDS ++ GF+A F
Sbjct: 260 DFLEI---SGTEAPSIWL-TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQF 309
Score = 52.4 bits (120), Expect = 5e-06
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG+V + CGG+L+A+ V Y Y+ C+W IEA H +K
Sbjct: 743 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGY----YKDSLHCEWIIEAKPGHSIK 798
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V + G + P ++ST + + F TD+S
Sbjct: 799 MTFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS 854
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 855 RSSIGFLIHYESV 867
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 12/119 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L T + + + YE+ ADC W I A + L F F+LE
Sbjct: 207 ACGGTLRGTSSS----ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----G 258
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
YD++++ G+ +P ++S+ L + F +D + KGF+A +Q+ K
Sbjct: 259 YDFLEI----SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Score = 50.0 bits (114), Expect = 3e-05
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 465 GSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
G+V+R + + A CGG LS V + S G +Y + DC W I P +
Sbjct: 1960 GTVRRWNYPSPLCIATCGGTLSTLGGV--ILSPGFPG--SYPNNLDCTWRISLPIGYGAH 2015
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+ FL F E AN +D++++ F G +P ++ST+ L+ F +D S
Sbjct: 2016 IQFLNFSTE--AN--HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS 2071
Query: 584 LVFKGFSASYQ 594
+GF +YQ
Sbjct: 2072 QNRQGFKLAYQ 2082
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
+ Y + A+C W I + ++L+F TF LE +D + V+ G
Sbjct: 50 HGYPNYANCTWIIITGERNRIQLSFHTFALEEN----FDILSVYDGQPQQGNLKVRLSGF 105
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++P IVST L + F TD ++ +GF A Y+++
Sbjct: 106 QLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVL 140
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ V ++ + Y +CDW ++ + + L F +F +E
Sbjct: 1451 ACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 1502
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 1503 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--G 560
YE A C W I + +KL F FELER YD + V + G
Sbjct: 432 YEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTG 487
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVS S + + ++DDS+ GF A YQ ++
Sbjct: 488 SSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIE 524
Score = 39.1 bits (87), Expect = 0.047
Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L F F++E + +D++ V TF G ++
Sbjct: 605 YGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDNGISDITVLGTFSGNEV 660
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P ++ S+ + + F++D S +GF+ +Y
Sbjct: 661 PSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
Score = 39.1 bits (87), Expect = 0.047
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ C W IEA + L F+ F+ E +D ++V+ + G +
Sbjct: 1299 YDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDILKVWDGPVDSDILLKEWSGSAL 1354
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P +I ST +L ++F +D + GFS +
Sbjct: 1355 PEDIHSTFNSLTLQFDSDFFISKSGFSIQF 1384
Score = 34.3 bits (75), Expect = 1.3
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 7/133 (5%)
Query: 462 KSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHF 521
K +Q +G L T C T + S Y N + S+ C W+I+ N+
Sbjct: 2303 KLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPG-YPGNYFNSQT-CSWSIKVEPNYN 2360
Query: 522 VKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM-PPEIVSTSEALLVRFRT 580
+ + TF+ E++ +D ++VF G S S L +R+ T
Sbjct: 2361 ITIFVDTFQSEKQ----FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWST 2416
Query: 581 DDSLVFKGFSASY 593
D + KGF Y
Sbjct: 2417 DHATSKKGFKIRY 2429
>AF333704-1|AAK73475.2| 3566|Homo sapiens CUB and sushi multiple
domains 1 protein protein.
Length = 3566
Score = 152 bits (368), Expect = 4e-36
Identities = 137/473 (28%), Positives = 210/473 (44%), Gaps = 70/473 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CG ++ + G L SPN+P +Y CI+K+ + LR SF++ DT
Sbjct: 1103 AECGASVK-GNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQLFEGDT---- 1157
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDI-RSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+KV DG S +G F +++ I STSN L + F ++ + GF T+ FD
Sbjct: 1158 -LKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS-FDL 1215
Query: 167 CASIDHGCSHSC--VNTLGGYE-----CACDIGYELHSDGK----------------KCE 203
D G + + G + +C+ GY +H C
Sbjct: 1216 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 204 NACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
CGG ++ +G I SP +P Y +C W I A P I+L+F FD E H
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAH----- 1330
Query: 263 CEYDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + V + +D+L + + G+ALP + S + L +QF SD + +SGF+ +
Sbjct: 1331 ---DILKVWDGPVDSDILLKE--WSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFS 1385
Query: 322 IDV-----DECAENNG---GCQHECHNTL-----GGYE--------CA-CHSGFTLHPNK 359
+ D NG G E +T+ GY+ C ++ F P+
Sbjct: 1386 TSIAATCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDP 1445
Query: 360 HDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C C ++T P G I SPNYP YP K+C W+ P I LIF F +EP
Sbjct: 1446 PTC-IAACGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP--- 1501
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+YD + IY+G ++ +G + GS+ P + +S N +++ F+SD SV GF
Sbjct: 1502 -SYDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGF 1553
Score = 150 bits (364), Expect = 1e-35
Identities = 129/462 (27%), Positives = 193/462 (41%), Gaps = 66/462 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
C G+ G + SP YP+ Y N CIWK+ V + + F H
Sbjct: 1803 CSGNF-TQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQDPSDQF---CHGAELGLPF 1858
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFD 165
++ DG + +P +G F G +P + STSN+L + F+SD +V AGF + +
Sbjct: 1859 EIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ 1918
Query: 166 ECA----SIDHGCSHSCVNTLGGYECACDIGYELHS----------------DGKKCENA 205
E A SI G + VN + ++C + GY L C
Sbjct: 1919 EPALPSNSIKIGDRYM-VNDVLSFQC--EPGYTLQGRSHISCMPGTVRRWNYPSPLCIAT 1975
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G I SP FP YP +C W I P + + F +F E NH + E
Sbjct: 1976 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF---LEI 2032
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI-DV 324
+ H+ G F GT LP + S + F SD S +R GF Y ++
Sbjct: 2033 QNGPYHTS------PMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYEL 2086
Query: 325 DECAE----NNGGCQHECHNTLGGYECACHSGFTL--HPNKHDCKEG------------- 365
C + NG + ++ C+ G+ L HP C+ G
Sbjct: 2087 QNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVL-TCQHGINRNWNYPFPRCD 2145
Query: 366 -GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
C ++VT +GTI+SP +P YP KDC+W + PGH + + F + + E D+
Sbjct: 2146 APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQ----TEAVNDY 2201
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
+ ++DG + LG+F G+ +S NQ+ + F SD S
Sbjct: 2202 IAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFS 2243
Score = 148 bits (359), Expect = 5e-35
Identities = 139/478 (29%), Positives = 209/478 (43%), Gaps = 63/478 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG++ + G + SPNYP Y P K C W++ V D+ +AL F SF +E SYD
Sbjct: 1450 AACGGNLTGPA-GVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEP----SYD 1504
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+ + +G+ +SPLIG + G + P I S+ N L + F SD++V +GF+ F KE
Sbjct: 1505 FLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEF-KEKPRE 1563
Query: 168 ASIDHG--CSHSCVNT---LGG-YECACDIGYEL----------HSDGK--------KCE 203
A D G + + V T LG CD GY++ +DGK C
Sbjct: 1564 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG G G + SP++P Y + CL+ I P + + F +F N + +
Sbjct: 1624 APCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAEL-- 1681
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFA--AVYY 321
+D ++L + + G+ G LP TS+ +LR S S F AV
Sbjct: 1682 -FDGTHAQARLLSSL---SGSHSGETLPL-ATSNQILLRFSAKSGASARGFHFVYQAVPR 1736
Query: 322 IDVDECA---ENNGGCQHECHNTLGGY-ECACHSGFTLH----------PNK----HDCK 363
+C+ E G + + G C+ G+ L PN +D
Sbjct: 1737 TSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
Query: 364 EG---GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C + T GTI SP YP Y +C+W+ T G I+ + F
Sbjct: 1797 PSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQDPSDQFCHGAELGL 1856
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
++ I+DG LG F G+ +P L+ ++ NQ+Y+ F+SD SV GF + T
Sbjct: 1857 PFE---IHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKT 1911
Score = 146 bits (353), Expect = 3e-34
Identities = 134/470 (28%), Positives = 194/470 (41%), Gaps = 63/470 (13%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I ++G + SP YP Y N C W + ++L F F+ E ++D
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHD 1331
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF--- 164
+KV DG L+ + G +P DI ST N L + F+SD + K+GFS F
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 165 -DECASIDHGCSHSCVNTLGG-YECACDIGYELHSDGK-----------------KCENA 205
++ +G + G CD GY+L K C A
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIAA 1451
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G I SP++P+ YPP K C W + P I L F F++E ++ + Y
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLH--IY 1509
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ +S L G++ G+ P + S G+ L + F SD SV SGFA +
Sbjct: 1510 EGEDSNSPL-------IGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1562
Query: 326 ECAENNG----GCQHECHNTLGG-YECACHSGF-TLHPNKHDC---KEGGCKHDVTLP-- 374
E + G G + LG C SG+ L P+ C +G D LP
Sbjct: 1563 EACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC 1622
Query: 375 -----------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
G + SPNYP Y A + C++ T P + +F F Q D
Sbjct: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSI-TVPKEFV--VFGQFAY--FQTALND 1677
Query: 424 HVTIYDGASADVKTLGIFCGSKLPH-LVMASQNQMYMVFKSDGSVQRKGF 472
++DG A + L GS L +A+ NQ+ + F + +GF
Sbjct: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGF 1727
Score = 142 bits (343), Expect = 5e-33
Identities = 136/494 (27%), Positives = 212/494 (42%), Gaps = 74/494 (14%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG + G + SP +P Y N C W++S+P Y ++F +F E ++D
Sbjct: 1974 ATCGGTLST-LGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTE----ANHD 2028
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++++G SP+IG F G +P + ST+++ L+ F SD + + GF + E
Sbjct: 2029 FLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQN 2088
Query: 167 CA---------------SIDHGCSHSCV--NTLGGY---ECACDIGYELHSDGKKCENAC 206
C S+ S C L G+ C I + +C+ C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCDAPC 2148
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
G + NGTI SP FP+ YP LK+C+W I PP H + +NFT + Q E D
Sbjct: 2149 GYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFT--------LLQTEAVND 2200
Query: 267 SVTVHSKLGADV-LRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY--I 322
+ V G D + G F G TAL +S VL ++F SD S GF + +
Sbjct: 2201 YIAVWD--GPDQNSPQLGVFSGNTALETAYSSTNQVL-LKFHSDFS--NGGFFVLNFHAF 2255
Query: 323 DVDECAENNGGCQHECHNTLGGYECA------CHSGFTL-HPNKHDCK-------EGG-- 366
+ +C Q E +E CH G+TL + CK EG
Sbjct: 2256 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2315
Query: 367 -CK-----HDV-TLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE 419
C+ ++V T G I SP YP Y + C W P + I + + F+ E
Sbjct: 2316 TCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQ-- 2373
Query: 420 CAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQ-NQMYMVFKSDGSVQRKGFLATHST 478
+D + ++DG+S L + G+ S+ NQ+Y+ + +D + +KGF ++
Sbjct: 2374 --FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAA 2431
Query: 479 ACGGYLSATEEVKH 492
Y S T +K+
Sbjct: 2432 P---YCSLTHPLKN 2442
Score = 140 bits (340), Expect = 1e-32
Identities = 123/468 (26%), Positives = 194/468 (41%), Gaps = 62/468 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQ-DYQVALRFHSFEVENHDTCSYDK 108
CG ++ S G + SPNYP Y+ N C+W ++ D + L F FE+E YD
Sbjct: 412 CGSNLRGPS-GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER----GYDT 466
Query: 109 VKVRDGDSMDSP--LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFD 165
+ V D + ++ + G +P I S SN++ + +SD ++ GF A + + E
Sbjct: 467 LTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKG 526
Query: 166 EC-------------ASIDHG--CSHSC---VNTLGGYECACDIGYELHSDGKKCENACG 207
C +S HG + C +G C + + C +C
Sbjct: 527 GCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCF 586
Query: 208 GALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS 267
+G I SP++PE Y NC+W I++ P RI L F FD+E ++D
Sbjct: 587 FNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP--------QFDF 638
Query: 268 VTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YIDVDE 326
+ V G + G F G +P + S G ++R++F SD S GF Y +E
Sbjct: 639 LAVKDD-GISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNE 697
Query: 327 CAEN----NG---------------GCQHECHNTLGGYECAC--HSGFTLHPNKHDCKEG 365
C + NG C T G C G + + E
Sbjct: 698 CHDPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEA 757
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
C +T G I P +P Y C W PGH IK+ F+ F+ E + YD +
Sbjct: 758 PCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRFQTEVN----YDTL 813
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
+ DG ++ +G + G++ P ++++ N MY++F +D S GFL
Sbjct: 814 EVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFL 861
Score = 140 bits (339), Expect = 1e-32
Identities = 124/476 (26%), Positives = 205/476 (43%), Gaps = 63/476 (13%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
EA CGG + S+G + P +P Y+ + C W + + + + F F+ E +Y
Sbjct: 756 EAPCGGHLTA-SSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRFQTE----VNY 810
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK---E 163
D ++VRDG + SPLIG + G + P + ST N + ++F +D++ GF + E
Sbjct: 811 DTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLE 870
Query: 164 FDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDG--------------KKCE 203
D C +D G H G +CD GY L D C+
Sbjct: 871 SDSC--LDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
CGG + G +GT+ SP FP+ YP NC W I + + F F LE +H
Sbjct: 929 ALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSH------ 982
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY-YI 322
+Y +T V R G+ + + + + +++F SD S+ GF +
Sbjct: 983 DYLLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTA-QLRFISDFSISYEGFNITFSEY 1041
Query: 323 DVDECAENNGGC---QHECHNTLG-GYECACHSGFTLH-PNKHDCKEGG----------- 366
D++ C + + H +G +C G+ L K C GG
Sbjct: 1042 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Query: 367 ---CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C V GT+ SPN+P+ Y +C+++ T G I L F+L D
Sbjct: 1102 VAECGASVKGNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQL-----FEGD 1156
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATHST 478
+ +YDG + + LG F ++L L++ ++ N +++ F ++GS +GF T+++
Sbjct: 1157 TLKVYDGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS 1212
Score = 136 bits (328), Expect = 3e-31
Identities = 123/466 (26%), Positives = 194/466 (41%), Gaps = 64/466 (13%)
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S+G + SPNYP++Y N C+W + ++ L F+ F+VE +D + V+D
Sbjct: 592 SSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEP----QFDFLAVKDDGIS 647
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDEC--------- 167
D ++G F G+++P + S+ + + + F+SD + GF+ T+ +EC
Sbjct: 648 DITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPING 707
Query: 168 ----------ASIDHGCSHSCVNTLGGYECAC---DIGYELHSDGKKCENACGGALYGPN 214
+S+ C V T G C D S +CE CGG L +
Sbjct: 708 RRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASS 767
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I P +P Y +C W I A P H I + F F Q E YD++ V
Sbjct: 768 GVILPPGWPGYYKDSLHCEWIIEAKPGHSIKMTFDRF--------QTEVNYDTLEVRDG- 818
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---YIDVDECAENN 331
A G + GT P + S G+ + + FT+D S GF Y ++ D C +
Sbjct: 819 PASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPG 878
Query: 332 GGCQHECHNTLGGYEC----ACHSGFTLHPNKHDCKEGGCKHDVTLP------------- 374
H G +C G+TL ++ E + + LP
Sbjct: 879 IPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGK 938
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
GT+ SP +P YP +C W + G +++IF+ F H E ++D++ I + S
Sbjct: 939 SGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTF----HLESSHDYLLITEDGSFS 994
Query: 435 VKTLGIFCGSKLPHLVMA---SQNQMYMVFKSDGSVQRKGFLATHS 477
+ + GS LPH + A + F SD S+ +GF T S
Sbjct: 995 -EPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFS 1039
Score = 118 bits (285), Expect = 5e-26
Identities = 90/295 (30%), Positives = 133/295 (45%), Gaps = 36/295 (12%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFTHFDLEGNHMYQQECE 264
CG L GP+G ITSP++P Y +C+W I P I L F F+LE
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERG-------- 463
Query: 265 YDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY- 321
YD++TV K+G D G+++P + S + + + SD S+ GF AVY
Sbjct: 464 YDTLTVGDAGKVG-DTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQE 522
Query: 322 IDVDECAE---------------NNGGCQHEC---HNTLGGYECACHSGFTLHPNKHDCK 363
I+ C + + EC +G C NK C
Sbjct: 523 IEKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV 582
Query: 364 EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYD 423
C + T G I SPNYP Y +CVW + PG RI LIFN F++EP +D
Sbjct: 583 FS-CFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FD 637
Query: 424 HVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
+ + D +D+ LG F G+++P + +S + + + F+SD S +GF T++T
Sbjct: 638 FLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFNITYTT 692
Score = 114 bits (274), Expect = 1e-24
Identities = 95/293 (32%), Positives = 127/293 (43%), Gaps = 41/293 (13%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + GPNGTI SP FP YP NC W I+ ++RI L+F F LE N + Y
Sbjct: 32 CGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN--FDILSVY 89
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D L G LP + S GS+L + FT+D +V GF A+Y +
Sbjct: 90 DGQPQQGNLKV-------RLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPS 142
Query: 326 ECAENNG----GCQHECHNTLG---------GYECACHSGFT--LHPNKHD--------C 362
N G G H +G GY H+ T + P C
Sbjct: 143 HTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
Query: 363 K-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
+ EG C + +I SP++P+ Y DC W PG I L+F F+LE
Sbjct: 203 RAEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----G 258
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA 474
YD + I G A L G LP V++S+N + + F SD + +RKGF A
Sbjct: 259 YDFLEI-SGTEAPSIWL---TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNA 307
Score = 108 bits (259), Expect = 7e-23
Identities = 133/483 (27%), Positives = 199/483 (41%), Gaps = 73/483 (15%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+A+CGG I+ S G + SP +PD Y PN L C W + V V + FH+F +E+ S
Sbjct: 928 DALCGGYIQGKS-GTVLSPGFPDFY-PNSLNCTWTIEVSHGKGVQMIFHTFHLES----S 981
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPPDIRST---SNKLLVIFESDSTVQKAGFSATFMK 162
+D + + + S P + G +P I++ + + F SD ++ GF+ TF
Sbjct: 982 HDYLLITEDGSFSEP-VARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITF-S 1039
Query: 163 EFDECASIDHGC---SHSCVNTLG---GYECACDIGYELHSDGK---------------- 200
E+D D G S G +C +GY L K
Sbjct: 1040 EYDLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
Query: 201 KCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+C CG ++ G GT+ SP+FP Y C+++I I L F L
Sbjct: 1100 RCVAECGASVKGNEGTLLSPNFPSNYDNTHECIYKIETEAGKGIHLRTRSFQL------- 1152
Query: 261 QECEYDSVTVHSKLGADVLRRH-GAFCGTALPPPV-TSDGSVLRVQFTSDGSVHRSGFAA 318
E D++ V+ G D R G F L + S + L ++F ++GS GF
Sbjct: 1153 --FEGDTLKVYD--GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQL 1208
Query: 319 VY-YIDVDECAE----NNG-GCQHECHNTLGGYECACHSGFTLH-PNKHDCKEGGCK-HD 370
Y D+ +C + N G + E H T +C+ G+ +H N C G + D
Sbjct: 1209 TYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWD 1268
Query: 371 VTLP--------------HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP 416
LP G I SP YPA Y C W PG I L F VF+
Sbjct: 1269 KPLPSCIAECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFD--- 1325
Query: 417 HQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
E A+D + ++DG L + GS LP + ++ N + + F SD + + GF
Sbjct: 1326 -TEMAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQF 1384
Query: 477 STA 479
ST+
Sbjct: 1385 STS 1387
Score = 101 bits (242), Expect = 8e-21
Identities = 88/298 (29%), Positives = 124/298 (41%), Gaps = 43/298 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ L FH+F +E + +D +
Sbjct: 32 CGGLVQ-GPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN----FDIL 86
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF-MKEFDECA 168
V DG L G ++P I ST + L + F +D V GF A + + C
Sbjct: 87 SVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHTCG 146
Query: 169 S---IDHGCSHSCVNTLGG---YECACDIGYELH-------SDGK-----------KCEN 204
+ I G H +G Y C E H S G + E
Sbjct: 147 NPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEG 206
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG L G + +I+SP FP Y +C W I+A P I L FT F LE
Sbjct: 207 ACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEG-------- 258
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
YD + + + G LP PV S + LR+ FTSD + R GF A + +
Sbjct: 259 YDFLEISGTEAPSIW-----LTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQV 311
Score = 77.8 bits (183), Expect = 1e-13
Identities = 45/118 (38%), Positives = 63/118 (53%), Gaps = 7/118 (5%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNVFELEPHQEC 420
C+ C ++ P G I SPNYP Y CVW +TT P IKL F FELE
Sbjct: 407 CRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELER---- 462
Query: 421 AYDHVTIYD-GASADVKT-LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
YD +T+ D G D ++ L + GS +P L+++ NQM++ +SD S+ GF A +
Sbjct: 463 GYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVY 520
Score = 72.1 bits (169), Expect = 5e-12
Identities = 64/232 (27%), Positives = 99/232 (42%), Gaps = 29/232 (12%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+A CG ++ NG + SP +PD+Y K CIW ++VP + V + F + E
Sbjct: 2145 DAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTE----AVN 2199
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDST---VQKAGFSATFMKE 163
D + V DG +SP +G+F G+ S++N++L+ F SD + F A +K+
Sbjct: 2200 DYIAVWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKK 2259
Query: 164 F--------------DECASIDHGCSHSC--VNTLGGYE-CACDIGYELHSDGK--KCEN 204
D+ I + C TL G + C + +L +G CE
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2319
Query: 205 AC--GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
C G +G I SP +P Y + C W I P + IT+ F E
Sbjct: 2320 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSE 2371
Score = 61.7 bits (143), Expect = 8e-09
Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 6/116 (5%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
EA C ++ S+G + SP YP +Y ++ C W + V +Y + + +F+ E
Sbjct: 2318 EAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEK----Q 2373
Query: 106 YDKVKVRDGDSMDSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+D ++V DG S SPL+ + G H + S SN+L + + +D K GF +
Sbjct: 2374 FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRY 2429
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/114 (30%), Positives = 58/114 (50%), Gaps = 4/114 (3%)
Query: 363 KEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY 422
K C V P+GTI SP +P YP +C W T +RI+L F+ F LE + +
Sbjct: 28 KGQNCGGLVQGPNGTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEN----F 83
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
D +++YDG G +LP ++++ + + + F +D +V +GF A +
Sbjct: 84 DILSVYDGQPQQGNLKVRLSGFQLPSSIVSTGSILTLWFTTDFAVSAQGFKALY 137
Score = 56.0 bits (129), Expect = 4e-07
Identities = 34/114 (29%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+ + SP++P +Y+ N C W + +AL F F++E Y
Sbjct: 205 EGACGGTLRGTSSS-ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----GY 259
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ ++P I + G +P + S+ N L + F SDS ++ GF+A F
Sbjct: 260 DFLEI---SGTEAPSIWL-TGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQF 309
Score = 52.4 bits (120), Expect = 5e-06
Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 8/133 (6%)
Query: 464 DGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
DG+V + CGG+L+A+ V Y Y+ C+W IEA H +K
Sbjct: 743 DGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGY----YKDSLHCEWIIEAKPGHSIK 798
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+TF F+ E YD ++V + G + P ++ST + + F TD+S
Sbjct: 799 MTFDRFQTE----VNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNS 854
Query: 584 LVFKGFSASYQMV 596
GF Y+ V
Sbjct: 855 RSSIGFLIHYESV 867
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 12/119 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L T + + + YE+ ADC W I A + L F F+LE
Sbjct: 207 ACGGTLRGTSSS----ISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEE----G 258
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
YD++++ G+ +P ++S+ L + F +D + KGF+A +Q+ K
Sbjct: 259 YDFLEI----SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKK 313
Score = 50.0 bits (114), Expect = 3e-05
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 9/131 (6%)
Query: 465 GSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVK 523
G+V+R + + A CGG LS V + S G +Y + DC W I P +
Sbjct: 1960 GTVRRWNYPSPLCIATCGGTLSTLGGV--ILSPGFPG--SYPNNLDCTWRISLPIGYGAH 2015
Query: 524 LTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDS 583
+ FL F E AN +D++++ F G +P ++ST+ L+ F +D S
Sbjct: 2016 IQFLNFSTE--AN--HDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTTHETLIHFYSDHS 2071
Query: 584 LVFKGFSASYQ 594
+GF +YQ
Sbjct: 2072 QNRQGFKLAYQ 2082
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 4/95 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
+ Y + A+C W I + ++L+F TF LE +D + V+ G
Sbjct: 50 HGYPNYANCTWIIITGERNRIQLSFHTFALEEN----FDILSVYDGQPQQGNLKVRLSGF 105
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++P IVST L + F TD ++ +GF A Y+++
Sbjct: 106 QLPSSIVSTGSILTLWFTTDFAVSAQGFKALYEVL 140
Score = 46.4 bits (105), Expect = 3e-04
Identities = 27/116 (23%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG L+ V ++ + Y +CDW ++ + + L F +F +E
Sbjct: 1451 ACGGNLTGPAGVILSPNYPQ----PYPPGKECDWRVKVNPDFVIALIFKSFNMEPS---- 1502
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YD++ ++ ++ G + P I S+ +L + FR+D S+ GF+ ++
Sbjct: 1503 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFK 1558
Score = 41.9 bits (94), Expect = 0.007
Identities = 31/97 (31%), Positives = 43/97 (44%), Gaps = 7/97 (7%)
Query: 504 YESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--G 560
YE A C W I + +KL F FELER YD + V + G
Sbjct: 432 YEDNAHCVWVITTTDPDKVIKLAFEEFELERG----YDTLTVGDAGKVGDTRSVLYVLTG 487
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+P IVS S + + ++DDS+ GF A YQ ++
Sbjct: 488 SSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIE 524
Score = 39.1 bits (87), Expect = 0.047
Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + +C W I + + L F F++E + +D++ V TF G ++
Sbjct: 605 YGNNMNCVWLIISEPGSRIHLIFNDFDVEPQ----FDFLAVKDDGISDITVLGTFSGNEV 660
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P ++ S+ + + F++D S +GF+ +Y
Sbjct: 661 PSQLASSGHIVRLEFQSDHSTTGRGFNITY 690
Score = 39.1 bits (87), Expect = 0.047
Identities = 23/90 (25%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y++ C W IEA + L F+ F+ E +D ++V+ + G +
Sbjct: 1299 YDNNLHCTWIIEADPGKTISLHFIVFDTE----MAHDILKVWDGPVDSDILLKEWSGSAL 1354
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
P +I ST +L ++F +D + GFS +
Sbjct: 1355 PEDIHSTFNSLTLQFDSDFFISKSGFSIQF 1384
Score = 34.3 bits (75), Expect = 1.3
Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 7/133 (5%)
Query: 462 KSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHF 521
K +Q +G L T C T + S Y N + S+ C W+I+ N+
Sbjct: 2303 KLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPG-YPGNYFNSQT-CSWSIKVEPNYN 2360
Query: 522 VKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM-PPEIVSTSEALLVRFRT 580
+ + TF+ E++ +D ++VF G S S L +R+ T
Sbjct: 2361 ITIFVDTFQSEKQ----FDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWST 2416
Query: 581 DDSLVFKGFSASY 593
D + KGF Y
Sbjct: 2417 DHATSKKGFKIRY 2429
>Y18287-2|CAB50735.1| 686|Homo sapiens MASP-2 protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (309), Expect = 6e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAHAC 300
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAHAC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y18286-2|CAB50733.1| 686|Homo sapiens MASP-2 protein protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (309), Expect = 6e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAHAC 300
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAHAC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y09926-1|CAA71059.1| 686|Homo sapiens MASP-2 protein protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (309), Expect = 6e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAHAC 300
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAHAC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>X98400-1|CAA67050.1| 686|Homo sapiens mannan-binding
lectin-associated serine protease-2 protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (309), Expect = 6e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAHAC 300
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAHAC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AL109811-4|CAI22102.1| 686|Homo sapiens mannan-binding lectin
serine peptidase 2 protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (310), Expect = 5e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPC 300
Score = 67.7 bits (158), Expect = 1e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAQPC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AF321562-1|AAG50274.1| 686|Homo sapiens MBL-associated serine
protease 2 protein.
Length = 686
Score = 147 bits (357), Expect = 9e-35
Identities = 101/275 (36%), Positives = 129/275 (46%), Gaps = 30/275 (10%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
+DEC G C H CHN LGG+ C+C +G+ LH NK C T G + S
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSS 198
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKT 437
P YP YP C + S G + L F F++E H E C YD + I D +
Sbjct: 199 PEYPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREE 254
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
G FCG LPH + N + + F +D S G+
Sbjct: 255 HGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGW 289
Score = 128 bits (309), Expect = 6e-29
Identities = 83/281 (29%), Positives = 130/281 (46%), Gaps = 21/281 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYP 227
G C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYP 206
Query: 228 PLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFC 286
L +C + I + L+F FD+E + + C YD + + + HG FC
Sbjct: 207 KLSSCTYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFC 259
Query: 287 GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
G LP + + + + + F +D S +G+ Y C
Sbjct: 260 GKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAHAC 300
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 174 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 232
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
VE H C YD +K++ D G FCG +P I + SN + + F +D + G
Sbjct: 233 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTG 288
Query: 156 FSATFMKEFDEC 167
+ + C
Sbjct: 289 WKIHYTSTAHAC 300
Score = 34.7 bits (76), Expect = 1.0
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 205 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 260
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+P I + S + + F TD+S G+ Y
Sbjct: 261 KTLPHRIETKSNTVTITFVTDESGDHTGWKIHY 293
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 140 bits (340), Expect = 1e-32
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 1508 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC---- 1563
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 1564 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 1623
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 1624 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 1679
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 1727
Score = 139 bits (336), Expect = 3e-32
Identities = 109/398 (27%), Positives = 172/398 (43%), Gaps = 50/398 (12%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 264 EYDSVTVHSKLGADVL---RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+Y + + + L +G FCG+ + + + + VQF SD S GF Y
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 321 YIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
C GG + H+ A +G+ PN PH
Sbjct: 2211 EAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH----- 2239
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKTLG 439
NYP DC+W + P RI+L F + F++E C +++ + DG +D L
Sbjct: 2240 -NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILS 2294
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHAR 498
FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 2295 KFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPT 2354
Query: 499 --YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 2355 LPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNILG 2408
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 2409 RYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 2446
Score = 135 bits (327), Expect = 4e-31
Identities = 80/231 (34%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G I SP Y A YP C++ + + I+L F+ F++ P C++D++ IYDGA+
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTS 3105
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF-LATHST-----ACGGYLSATE 488
LG FCGSK P V +S N M +VFK+D KG+ ++ T CGGYL+ +
Sbjct: 3106 DPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSN 3165
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA---NCRYDYVQVF 545
S + Y+ +C W I AP N + LTF TF LE + C YDYV+++
Sbjct: 3166 NT--FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLY 3223
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
TFCG +P +S+ L V+F +D +L +GF+A+Y ++
Sbjct: 3224 DGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3274
Score = 132 bits (318), Expect = 5e-30
Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
SGF+ + D GC ++T GT SPNYP Y +C W ++ G +L F
Sbjct: 1152 SGFSAY---WDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFK 1208
Query: 411 VFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRK 470
F LE H C D++ +YDG S++ L CG + P L+ +S + M++ ++D Q +
Sbjct: 1209 DFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGR 1268
Query: 471 GFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFE 530
GF A + C + + L S N Y C+W I A + V TFL F+
Sbjct: 1269 GFKAEYRQTCENVVIVNQTYGILESIGY--PNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326
Query: 531 LEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
LE NC DY++++ +CG+ +PP +TS L V TD
Sbjct: 1327 LEHHINCSTDYLELY----DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 124 bits (298), Expect = 1e-27
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 8/232 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY-DHV 425
C D T GT SPN+P YP +C+++ + G I + F F LE Y D +
Sbjct: 1048 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFL 1107
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLAT---HSTACGG 482
I DG LGIF GS LP +++ N++++ FKSD R GF A ST CGG
Sbjct: 1108 EIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGG 1167
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L+ + + Y Y S ++C W +++ +L F F LE NC DY+
Sbjct: 1168 NLTTSSGT---FISPNYPMPYYHS-SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1223
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
V+ CG + PP I S+ +++ ++ RTD+ +GF A Y+
Sbjct: 1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1275
Score = 123 bits (297), Expect = 2e-27
Identities = 64/171 (37%), Positives = 97/171 (56%), Gaps = 2/171 (1%)
Query: 3 DAPVLGRLCGSGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D P++ RLCG K + + S++ + + R++ H GF A Y G I++ +G
Sbjct: 2641 DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVE-HIGFHAKYSFTDCGGIQIGDSGV 2699
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
+ SPNYP+ Y C L PQ + + L F F++E H TC++D V VR+G S +SP+
Sbjct: 2700 ITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPI 2759
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH 172
IG +CG+ P I+S SN+L+V F SD ++Q GF AT+ + C I H
Sbjct: 2760 IGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFH 2810
Score = 121 bits (292), Expect = 7e-27
Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T G I SP +P YP + C W I L F VFE+ C D+V
Sbjct: 817 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGGY 483
I + +CG+ +P + + N +Y+ F S + GF+A S ACG
Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L TE + S N Y +C W+I NH + L F TF LE NC DY++
Sbjct: 936 L--TESTGTIQSPGH--PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991
Query: 544 VFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
V+ +CG +PP + S+ +L++ F TD L ++GF +Y+ +
Sbjct: 992 VYDTDSETSLGR--YCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 1042
Score = 118 bits (283), Expect = 8e-26
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 1742
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 1743 YMAEGI---FNSPGYPD-IYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEI 1798
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 1799 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 1850
Score = 115 bits (276), Expect = 6e-25
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 1390 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 1449
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 1450 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 1509
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I RNH V L F F+LE + +C
Sbjct: 1510 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC-- 1563
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 1564 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1617
Score = 114 bits (274), Expect = 1e-24
Identities = 68/233 (29%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
HG + SP +P YP + W + H + ++E Q C YD + IYDG S
Sbjct: 1860 HGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIH 1919
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST--------------AC 480
+ +G +CG++ ++ N + F SD S+ KGFL AC
Sbjct: 1920 ARLIGAYCGTQTESF-SSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGAC 1978
Query: 481 GGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYD 540
GG+L + L+S ++Y +R DC W I+AP + V+L L+ ++E C YD
Sbjct: 1979 GGFLRTGDAPVFLFSPG--WPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYD 2035
Query: 541 YVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+ + CG ++P I ST E + +RF +D S+ GF+AS+
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 111 bits (267), Expect = 7e-24
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
K ++ C +T GTI SP +P YP +C W P H I L+F F LE H
Sbjct: 924 KFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 983
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS- 477
C D++ +YD S +LG +CG +P + +S N + +VF +D + +GFL +
Sbjct: 984 NCTNDYLEVYDTDSE--TSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEA 1041
Query: 478 -TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
+A L + ++ + +N Y + +C + I + + F F LE
Sbjct: 1042 ISAATACLQDYTDDLGTFTSPNFPNN-YPNNWECIYRITVRTGQLIAVHFTNFSLEEAIG 1100
Query: 537 CRY-DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSA 591
Y D++++ F G +PP I+S S L ++F++D GFSA
Sbjct: 1101 NYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 107 bits (258), Expect = 9e-23
Identities = 67/225 (29%), Positives = 110/225 (48%), Gaps = 13/225 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G I SPNYP AY + C GH I L F+ F++EPH CA+D VT+ +G S +
Sbjct: 2698 GVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPES 2757
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGG-YLSATEEVK 491
+G +CG+ P + + NQ+ + F SD S+Q GF AT +T CGG + S ++
Sbjct: 2758 PIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIR 2817
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFEL--EREANCRYDYVQVFX-XX 548
+ + +N SR C W ++ ++++F L + C+ +V+V+
Sbjct: 2818 SPHWPQNFPEN---SR--CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
T CG P +++ S F++ ++ +GFSAS+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPA-QGFSASF 2916
Score = 104 bits (249), Expect = 1e-21
Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%)
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDG 430
V +G + S YP Y + C W T G+ + F F+LE H C+ D++ +YDG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343
Query: 431 ASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYLSATE 488
+ +G +CG LP + +++ ++ +DG +R KGF + CGG LS
Sbjct: 1344 P----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGAT 1399
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXX 548
+S + N Y +C W I ++LT F++E + C +D ++++
Sbjct: 1400 GS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGP 1455
Query: 549 XXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 1456 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 103 bits (248), Expect = 1e-21
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 12/236 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2511
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 2512 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2571
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTFELEREANCRY 539
G L T E + S G Y +C+W + P N + + F F LE +C++
Sbjct: 2572 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQF 2630
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMP--PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D ++ F CG P P ++ S+ + + F T++ + GF A Y
Sbjct: 2631 DVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKY 2684
Score = 103 bits (246), Expect = 3e-21
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 9/227 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P G +F P + + CV+ G +I++ F EL+ + + +++
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG + LG CG+ + + N +++ FK D SV++ F A + ACG L+
Sbjct: 768 VRDGETL----LGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 823
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
++ + + N Y C W I P++ + L F FE+ A+C DYV++
Sbjct: 824 EGVIR-----SPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGS 878
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG +P I S L V F S GF A +
Sbjct: 879 SSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF 925
Score = 101 bits (241), Expect = 1e-20
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 15/277 (5%)
Query: 323 DVDECAEN---NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIF 379
+++EC N NGG C + + + C C +T + C ++ +G+
Sbjct: 432 NINECLSNPCLNGGT---CVDGVDSFSCECTRLWT--GALCQVPQQVCGESLSGINGSFS 486
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLG 439
+ Y +C W T G +++ F F LE C ++ + +YDG S+ LG
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLG 546
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA---THSTACGGYLSATEEVKHLYSH 496
FCGS LPH +++S N +Y S+ +GF T CGG L T + S
Sbjct: 547 RFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGIL--TGPYGSIKSP 604
Query: 497 ARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
G+ Y DC W + + V TF T LE +C DY+++
Sbjct: 605 GYPGN--YPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLG 662
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FC P + +T + F +D + +GF +Y
Sbjct: 663 KFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 1577 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 1634
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 1635 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 1694
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 1695 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 1738
Score = 100 bits (239), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 1738 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVE 1797
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 1798 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 1853
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 1854 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1913
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 1914 DGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 2161 ICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 2220
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 2221 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 2280
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 2281 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 2335
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 10/220 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D G + SP +P Y KDC + H I L F+ +E EC D +
Sbjct: 3395 CNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLE 3454
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF--LATHS-TACGGY 483
+ +G++++ LG +CG+ LP+ V + N++Y+ FKSD +G+ + T S + CGG
Sbjct: 3455 VRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGT 3514
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L + ++ Y Y + C+W + AP V + F ++ +C +Y+
Sbjct: 3515 LYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570
Query: 544 VFXXXXXXXXXXXTFCG--IKMPPEIVSTSEALLVRFRTD 581
++ +CG + P V++S + ++F D
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAP-FVASSNQVFIKFHAD 3609
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 1347 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 1405
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 1406 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 1465
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 1466 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 1513
Score = 97.1 bits (231), Expect = 2e-19
Identities = 60/226 (26%), Positives = 106/226 (46%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 2049
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 2050 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 2106
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ +
Sbjct: 2107 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPP 2165
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 2166 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 2211
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 2036
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 2037 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 2096
Query: 169 SIDHG 173
D G
Sbjct: 2097 HADRG 2101
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/157 (36%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDI----EVDSNGHL 62
LGR CG P + S+G+ L +V+ L + GF YEA+ D G
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLA-YEGFLINYEAISAATACLQDYTDDLGTF 1059
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY-DKVKVRDGDSMDSPL 121
SPN+P++Y N CI++++V +A+ F +F +E Y D +++RDG SPL
Sbjct: 1060 TSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPL 1119
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSA 158
+G+F G +PP I S SNKL + F+SD ++GFSA
Sbjct: 1120 LGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 95.5 bits (227), Expect = 5e-19
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Query: 9 RLCGSGKG--PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPN 66
+ CG P+ S+ S V+++ G+ + R + A C D + G+L SP
Sbjct: 3352 QFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYH-KAFGNLRSPG 3410
Query: 67 YPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFC 126
+PD+Y +K C L+ PQ++ ++L FHS +EN C D ++VR+G + +SPL+G +C
Sbjct: 3411 WPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYC 3470
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG 173
G +P + S +N+L + F+SDS G+ + C +G
Sbjct: 3471 GTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGTLYG 3517
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 1689 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 1746
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 1805
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 1806 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 1851
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 2173 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 2231
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 2232 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 2291
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 2292 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 2331
Score = 92.3 bits (219), Expect = 5e-18
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 13/235 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ----ECAY 422
C + T P G I SPNYP Y +C + P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-TACG 481
D V I G S CG ++P + + + F S+ + GF ++ +CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMP-APLTIAGPVLLNFYSNEQITDFGFKFSYRIISCG 3038
Query: 482 GYLSATEEV--KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
G + + + YS+A Y ++ + C + I + ++L F F++ +C +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMH-----CLYTITVSDDKVIELKFSDFDVVPSTSCSH 3093
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+ ++ FCG K PP + S++ ++L+ F+TD KG+ S++
Sbjct: 3094 DYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR 3148
Score = 91.9 bits (218), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
LGR CGS + S+ + L +Y LR RGF +E CGG I G +
Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLR--NGRGFTVRWETQQPECGG-ILTGPYGSI 601
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
+SP YP +Y P + C+W + D V F + +E+HD C+ D +++RDG PL+
Sbjct: 602 KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLL 661
Query: 123 GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
G FC P +++T + F SDS + GF T++
Sbjct: 662 GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700
Score = 91.9 bits (218), Expect = 6e-18
Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 13/167 (7%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV------CGGDIEVDS 58
P+LG+ CGS + P ++S+ + + +V++ + +G++ + CGG + S
Sbjct: 3107 PLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTAKGWKMSFRQTLGPQQGCGGYL-TGS 3164
Query: 59 NGHLESPNYPDD--YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT---CSYDKVKVRD 113
N SP+ + Y N C+W + P + + L F++F +E T C YD VK+ D
Sbjct: 3165 NNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYD 3224
Query: 114 GDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
GDS ++ L G FCG +P S+ N L V F SD T+++ GF+AT+
Sbjct: 3225 GDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 352 GFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV 411
GFT+ + + ++ C +T P+G+I SP YP YP +DCVW T+P + F
Sbjct: 578 GFTV---RWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634
Query: 412 FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKG 471
LE H +C D++ I DG LG FC + + + + F SD + +G
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 694
Query: 472 FLATHSTA-----CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
F T+ T+ CGG + T+ L+ G + C + ++ P+ +++ F
Sbjct: 695 FHITYLTSPSDLRCGG--NYTDPEGELFLPELSGP--FTHTRQCVYMMKQPQGEQIQINF 750
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
EL+ +++ +Y++V CG I S + ++ +RF+ D S+
Sbjct: 751 THVELQCQSDSSQNYIEV----RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEK 806
Query: 587 KGFSASYQM 595
F A YQ+
Sbjct: 807 ASFRAVYQV 815
Score = 89.0 bits (211), Expect = 4e-17
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNG 60
+P+LG GS P + S ++L + ++ ++ GF A+++ CGG++ S+G
Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSD-QIDTRSGFSAYWDGSSTGCGGNLTT-SSG 1174
Query: 61 HLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
SPNYP Y + C W L L F F +E+H C+ D + V DG S +S
Sbjct: 1175 TFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSH 1234
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+ CG + PP IRS+ + + + +D Q GF A +
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 2289 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 2346
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 2347 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 2405
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 2406 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 2452
Score = 87.8 bits (208), Expect = 1e-16
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVE 99
GF+ Y + G + S+G + SP Y PN + C++ ++V D + L+F F+V
Sbjct: 3027 GFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV 3086
Query: 100 NHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSAT 159
+CS+D + + DG + PL+G FCG K PP+++S++N +L++F++DS G+ +
Sbjct: 3087 PSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146
Query: 160 F 160
F
Sbjct: 3147 F 3147
Score = 86.2 bits (204), Expect = 3e-16
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESP 65
+LG++CG+G ++S + + + ++ ++ FRA Y+ CG E+ G + SP
Sbjct: 774 LLGKVCGNGTISHIKSITNSVWIRFKIDASVEK-ASFRAVYQVACGD--ELTGEGVIRSP 830
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y + C W + PQ + L F FE+ + C D V++ + SP +
Sbjct: 831 FFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY 890
Query: 126 CGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
CG IP I S N L V F S+ + GF A F E C I
Sbjct: 891 CGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 1619 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 1674
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 1675 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
Query: 323 DVDEC 327
V C
Sbjct: 1734 SVSAC 1738
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA--VCGGDIEVDSNGH 61
+P + CG+ + S + L V + + H GF A + A + G+I +S G
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENH-GFMAKFSAEDLACGEILTESTGT 942
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
++SP +P+ Y C W + V ++ + L F +F +E H C+ D ++V D DS S
Sbjct: 943 IQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-- 1000
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG IPP + S+ N L+++F +DS + GF
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 1035
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 86/164 (52%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 1517
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V ++++V L F F++E D+C + DG S
Sbjct: 1518 S-GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSS 1572
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 1573 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 82.2 bits (194), Expect = 5e-15
Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-GHLES 64
+L +LCG K P++RS+G + + + + RGF+A Y C + V+ G LES
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTD-EGQQGRGFKAEYRQTCENVVIVNQTYGILES 1293
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGM 124
YP+ Y N+ C W + V F +F++E+H CS D +++ DG +G
Sbjct: 1294 IGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1349
Query: 125 FCGHKIPPDIRSTSNKLLVIFESD 148
+CG +PP +TS+KL V+ +D
Sbjct: 1350 YCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 81.8 bits (193), Expect = 7e-15
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 203 ENACGGALYGPNGTITSPSFPE--LYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+ CGG L G N T SP +Y NC+W I+AP I L F F LE +
Sbjct: 3154 QQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST-R 3212
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
Q C YD V ++ ++ G FCG+ +P P S G+ L VQF SD ++ R GF A Y
Sbjct: 3213 QRCLYDYVKLYDG-DSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 321 YI 322
I
Sbjct: 3272 TI 3273
Score = 81.4 bits (192), Expect = 9e-15
Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W IV+ P +R+ L+F F LE + Q+C
Sbjct: 1736 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS----QDC 1791
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 1792 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1847
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 2406 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 2463
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 2464 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 2523
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 2524 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Score = 79.8 bits (188), Expect = 3e-14
Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 16/184 (8%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 2576
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQ--DYQVALRFHSFEVENHDTCSYDKVKVR 112
G+ SP Y +Y N C W LS P + +++ F F +E+H C +D ++ R
Sbjct: 2577 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFR 2636
Query: 113 DGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
GD+ D PL+ CG P + +++ + F ++ V+ GF A + F +C I
Sbjct: 2637 VGDA-DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY--SFTDCGGIQ 2693
Query: 172 HGCS 175
G S
Sbjct: 2694 IGDS 2697
Score = 79.4 bits (187), Expect = 4e-14
Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 9/137 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG G +G ITSP++P Y L +C + AP H ITL F+ FD+E + C +
Sbjct: 2689 CGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPH----TTCAW 2744
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
DSVTV + G+ G +CG + P + S + L V F SD S+ GF A +
Sbjct: 2745 DSVTVRNG-GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTL 2803
Query: 326 ECAENNGGCQHECHNTL 342
C GG H + T+
Sbjct: 2804 GC----GGIFHSDNGTI 2816
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/238 (25%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP--HQECAYD 423
GC +GTI SP++P +P C W T +++ F+ L P +C
Sbjct: 2804 GCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNS 2863
Query: 424 HVTIYDGA-SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
V ++ G D L CG+ P V+ N VF+S +GF A+ + CG
Sbjct: 2864 FVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCGS 2922
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA----NCR 538
+ Y + Y++ +C + IEA V LTF++F LE + +C
Sbjct: 2923 NFTGPSG----YIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2978
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
D V + T CG +MP + LL F +++ + GF SY+++
Sbjct: 2979 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLL-NFYSNEQITDFGFKFSYRII 3035
Score = 75.8 bits (178), Expect = 4e-13
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G+I SP +P YPP ++C+W +V P +T F LE + +C
Sbjct: 590 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLE----HHDDCNK 645
Query: 266 DSVTVH-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + L D L G FC T PP+ + G R+ F SD + GF Y
Sbjct: 646 DYLEIRDGPLYQDPLL--GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 1842 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 1901
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 1902 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 74.9 bits (176), Expect = 8e-13
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L GTI SP P +YP NC W I+ P H I L F F LE + C
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE----FHYNCT 986
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + V+ D G +CG ++PP +TS G+ L + F +D + GF Y
Sbjct: 987 NDYLEVYD---TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 2205 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 2262
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 2263 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 2317
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 2318 SDNSPTHVGFKAKYSI 2333
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFY-----EAVCGGDIEVDSN 59
P+LG+ C + P +++TG + + ++ +GF Y + CGG+ D
Sbjct: 659 PLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISD-QGFHITYLTSPSDLRCGGNY-TDPE 716
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L P + + C++ + PQ Q+ + F E++ S + ++VRDG++
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET--- 773
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+G CG+ I+S +N + + F+ D++V+KA F A +
Sbjct: 774 -LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Query: 2 PDAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDS 58
P++P++G+ CG+ ++S ++L V + L+ GF A + CGG D
Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATWNTQTLGCGGIFHSD- 2812
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHD-TCSYDKVKVRDG-D 115
NG + SP++P ++ N C W + + + F ++F + + D C VKV G +
Sbjct: 2813 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
+D L+ CG+ P + + SN +F+S + GFSA+F+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASFV 2917
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
G ++ T I SPN C W + P ++K+ +L Q+C +++
Sbjct: 3279 GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTS-QDCTQNYL 3337
Query: 426 TIYDGASADVKTLGIFCG---SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ D + FCG S +P + +S + ++FKS G V R ++
Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVP-VFYSSMSTAMVIFKS-GVVNRNSRMSFTYQIADC 3395
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ +L S + DN Y++ DC + AP+NH + L F + +E CR D++
Sbjct: 3396 NRDYHKAFGNLRSPG-WPDN-YDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFL 3453
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+V +CG +P + S + L +RF++D +G+
Sbjct: 3454 EVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 68.9 bits (161), Expect = 5e-11
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L G G I SP FP +YP + C W I P I LNFT F++ + CE
Sbjct: 816 ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSS----AHCE 870
Query: 265 YDSVTVHSK--LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D V + S LG+ ++ +CGT +P +TS + L V F S GF A +
Sbjct: 871 TDYVEIGSSSILGSPENKK---YCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Query: 323 DVDEC----AENNGGCQHECHNTLGGYECACHSGFTLHPN 358
+ C E+ G Q H + + C + PN
Sbjct: 928 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPN 967
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 1446
Query: 266 DSVTVHSKLGADV-LRRHGAFC---GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 1447 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 1504
Query: 322 IDVDEC 327
C
Sbjct: 1505 AVTGGC 1510
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 2047 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 2104
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 2105 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSP 2164
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 2165 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 2031
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 2032 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSN 59
++P+LG+ CG+ + S + L + ++ + RG+ + + CGG + D
Sbjct: 3462 NSPLLGKYCGTLLPNPVFSQNNELYLRFKSD-SVTSDRGYEIIWTSSPSGCGGTLYGD-R 3519
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YP Y N C W L P V + F+ +++ C + + + DG + S
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASS 3579
Query: 120 PLIGMFCG--HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P G +CG I P + S SN++ + F +D + + F T+
Sbjct: 3580 PSSGPYCGGDTSIAPFVAS-SNQVFIKFHADYARRPSAFRLTW 3621
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEP----QDSC-- 1563
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 1564 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 2507
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 2508 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 2568 AVCGGSLPNTPEGNFTSPGYD 2588
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG GP+G I SP++P+ Y NC + I A P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 266 DSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D VH G V+ CG +P P+T G VL + F S+ + GF Y I
Sbjct: 2980 DG--VHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRI 3034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 190 DIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFT 249
D GYE+ + CGG LYG G+ TSP +P YP C W +VAP +T+NF
Sbjct: 3497 DRGYEIIWTSSP--SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFY 3554
Query: 250 HFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCG--TALPPPVTSDGSVLRVQFTS 307
++ +C + +T++ A G +CG T++ P V S V ++F +
Sbjct: 3555 FISIDD----PGDCVQNYLTLYDGPNAS-SPSSGPYCGGDTSIAPFVASSNQVF-IKFHA 3608
Query: 308 DGSVHRSGF 316
D + S F
Sbjct: 3609 DYARRPSAF 3617
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 2336 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 2391
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 2392 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2448
Query: 324 VDEC 327
++EC
Sbjct: 2449 MEEC 2452
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC + G+ SP YP YP C W G + + F ++ +C +++
Sbjct: 3510 GCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYL 3569
Query: 426 TIYDGASADVKTLGIFCGSKLPHL-VMASQNQMYMVFKSDGSVQRKGFLAT 475
T+YDG +A + G +CG +AS NQ+++ F +D + + F T
Sbjct: 3570 TLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLT 3620
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+ VCG + NG + Y + C W + + + F F +E+ D C +
Sbjct: 471 QQVCGESLS-GINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ ++V DGDS + +G FCG +P ++ S+ N L S+ GF+ + + E
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589
Query: 167 CASI 170
C I
Sbjct: 590 CGGI 593
Score = 57.6 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D +L CG+ GP++ + + T V+Q + P +GF A + + CG + S G+
Sbjct: 2875 DKALLATGCGNVAPGPVITPSNT-FTAVFQS--QEAPAQGFSASFVSRCGSNFTGPS-GY 2930
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSM 117
+ SPNYP Y N C + + V L F SF +E +C D V + G S+
Sbjct: 2931 IISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSV 2990
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S CG ++P + + + +L+ F S+ + GF ++
Sbjct: 2991 MSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 3032
Score = 56.0 bits (129), Expect = 4e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CG LS + +S+ R D Y +C W I+ +++TF F LE NC +
Sbjct: 474 CGESLSG---INGSFSY-RSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
+++QV+ FCG +P E++S+ AL ++ +GF+ ++ +P
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 588
Score = 55.2 bits (127), Expect = 7e-07
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD-S 58
+A + G CGS S+G+ LTV + L L+ GF A Y + CGG +
Sbjct: 3229 NANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE-REGFNATYTIMDMPCGGTYNATWT 3287
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
++ SPN D P +C W + P QV + + ++ + D C+ + ++++D
Sbjct: 3288 PQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGH 3346
Query: 119 SPLIGMFCGHKIP--PDIRSTSNKLLVIFESDSTVQKAGFSATF 160
FCG P S+ + +VIF+S + + S T+
Sbjct: 3347 GNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTY 3390
Score = 54.4 bits (125), Expect = 1e-06
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ ++ + AC GT TSP+FP YP C++ I I ++FT+F
Sbjct: 1034 GFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
Query: 252 DLE---GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
LE GN+ Y G + G F G+ LPP + S + L ++F SD
Sbjct: 1094 SLEEAIGNY-------YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSD 1146
Query: 309 GSVHRSGFAAVYYIDVDECAEN 330
RSGF+A + C N
Sbjct: 1147 QIDTRSGFSAYWDGSSTGCGGN 1168
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP +P+ Y K+C + AP H I+L F +E + EC D + V +
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENS----VECRNDFLEVRNGS 3459
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
++ G +CGT LP PV S + L ++F SD G+ ++ C
Sbjct: 3460 NSNSPLL-GKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGC 3511
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 1856 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 1911
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT +S G+ L F SD S+ GF ++
Sbjct: 1912 IYD--GPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 7/129 (5%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ + DG CGG L +GT SP++P Y C W + + L F F
Sbjct: 1153 GFSAYWDGSS--TGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDF 1210
Query: 252 DLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
LE + C D + V+ ++ CG PP + S G + ++ +D
Sbjct: 1211 HLE----HHPNCTLDYLAVYDGPSSN-SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ 1265
Query: 312 HRSGFAAVY 320
GF A Y
Sbjct: 1266 QGRGFKAEY 1274
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + S +P Y ++C W I A + + F FDLE +H+ C D + ++
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLE-HHI---NCSTDYLELY--- 1341
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 1342 --DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 1388
Score = 48.8 bits (111), Expect = 6e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 205 ACGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+CGG +G ITSP++ YP +CL+ I I L F+ FD+ + C
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV----VPSTSC 3091
Query: 264 EYDSVTVHSKLG-ADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
+D + ++ +D L G FCG+ PP V S + + + F +D
Sbjct: 3092 SHDYLAIYDGANTSDPLL--GKFCGSKRPPNVKSSNNSMLLVFKTD 3135
Score = 48.4 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE---NACGGALYGPNGTIT 218
+ +EC S +CV+ + + C C + G C+ CG +L G NG+ +
Sbjct: 431 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWT----GALCQVPQQVCGESLSGINGSFS 486
Query: 219 SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADV 278
S Y NC W I + + FT F LE C ++ + V+ +
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLES----MDNCPHEFLQVYDGDSSSA 542
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
+ G FCG++LP + S + L S+ + GF + EC
Sbjct: 543 FQL-GRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC 590
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + NGTI SP +P+ +P C W + + ++F + L + Q + +
Sbjct: 2805 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
V ++ L G CG P PV + + F S GF+A + V
Sbjct: 2865 VKVWAGTEEVDKALLATG--CGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF---VS 2918
Query: 326 ECAENNGG 333
C N G
Sbjct: 2919 RCGSNFTG 2926
Score = 46.4 bits (105), Expect = 3e-04
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P G + P + + C++ + P +I +NFTH +L +C+
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVEL--------QCQS 759
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
DS + ++ D G CG + S + + ++F D SV ++ F AVY +
Sbjct: 760 DSSQNYIEV-RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815
Score = 33.5 bits (73), Expect = 2.4
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 5/36 (13%)
Query: 323 DVDECAENNGGCQ----HECHNTLGGYEC-ACHSGF 353
D++EC NNGGC EC NT G C AC G+
Sbjct: 305 DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 340
>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 140 bits (340), Expect = 1e-32
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 1508 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC---- 1563
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 1564 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 1623
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 1624 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 1679
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 1727
Score = 139 bits (336), Expect = 3e-32
Identities = 109/398 (27%), Positives = 172/398 (43%), Gaps = 50/398 (12%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 264 EYDSVTVHSKLGADVL---RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+Y + + + L +G FCG+ + + + + VQF SD S GF Y
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 321 YIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
C GG + H+ A +G+ PN PH
Sbjct: 2211 EAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH----- 2239
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKTLG 439
NYP DC+W + P RI+L F + F++E C +++ + DG +D L
Sbjct: 2240 -NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILS 2294
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHAR 498
FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 2295 KFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPT 2354
Query: 499 --YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 2355 LPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNILG 2408
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 2409 RYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 2446
Score = 135 bits (327), Expect = 4e-31
Identities = 80/231 (34%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G I SP Y A YP C++ + + I+L F+ F++ P C++D++ IYDGA+
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTS 3105
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF-LATHST-----ACGGYLSATE 488
LG FCGSK P V +S N M +VFK+D KG+ ++ T CGGYL+ +
Sbjct: 3106 DPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSN 3165
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA---NCRYDYVQVF 545
S + Y+ +C W I AP N + LTF TF LE + C YDYV+++
Sbjct: 3166 NT--FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLY 3223
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
TFCG +P +S+ L V+F +D +L +GF+A+Y ++
Sbjct: 3224 DGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3274
Score = 132 bits (318), Expect = 5e-30
Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
SGF+ + D GC ++T GT SPNYP Y +C W ++ G +L F
Sbjct: 1152 SGFSAY---WDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFK 1208
Query: 411 VFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRK 470
F LE H C D++ +YDG S++ L CG + P L+ +S + M++ ++D Q +
Sbjct: 1209 DFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGR 1268
Query: 471 GFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFE 530
GF A + C + + L S N Y C+W I A + V TFL F+
Sbjct: 1269 GFKAEYRQTCENVVIVNQTYGILESIGY--PNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326
Query: 531 LEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
LE NC DY++++ +CG+ +PP +TS L V TD
Sbjct: 1327 LEHHINCSTDYLELY----DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 124 bits (298), Expect = 1e-27
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 8/232 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY-DHV 425
C D T GT SPN+P YP +C+++ + G I + F F LE Y D +
Sbjct: 1048 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFL 1107
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLAT---HSTACGG 482
I DG LGIF GS LP +++ N++++ FKSD R GF A ST CGG
Sbjct: 1108 EIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGG 1167
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L+ + + Y Y S ++C W +++ +L F F LE NC DY+
Sbjct: 1168 NLTTSSGT---FISPNYPMPYYHS-SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1223
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
V+ CG + PP I S+ +++ ++ RTD+ +GF A Y+
Sbjct: 1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1275
Score = 123 bits (297), Expect = 2e-27
Identities = 64/171 (37%), Positives = 97/171 (56%), Gaps = 2/171 (1%)
Query: 3 DAPVLGRLCGSGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D P++ RLCG K + + S++ + + R++ H GF A Y G I++ +G
Sbjct: 2641 DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVE-HIGFHAKYSFTDCGGIQIGDSGV 2699
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
+ SPNYP+ Y C L PQ + + L F F++E H TC++D V VR+G S +SP+
Sbjct: 2700 ITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPI 2759
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH 172
IG +CG+ P I+S SN+L+V F SD ++Q GF AT+ + C I H
Sbjct: 2760 IGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFH 2810
Score = 121 bits (292), Expect = 7e-27
Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T G I SP +P YP + C W I L F VFE+ C D+V
Sbjct: 817 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGGY 483
I + +CG+ +P + + N +Y+ F S + GF+A S ACG
Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L TE + S N Y +C W+I NH + L F TF LE NC DY++
Sbjct: 936 L--TESTGTIQSPGH--PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991
Query: 544 VFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
V+ +CG +PP + S+ +L++ F TD L ++GF +Y+ +
Sbjct: 992 VYDTDSETSLGR--YCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 1042
Score = 118 bits (283), Expect = 8e-26
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 1742
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 1743 YMAEGI---FNSPGYPD-IYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEI 1798
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 1799 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 1850
Score = 115 bits (276), Expect = 6e-25
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 1390 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 1449
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 1450 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 1509
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I RNH V L F F+LE + +C
Sbjct: 1510 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC-- 1563
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 1564 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1617
Score = 114 bits (274), Expect = 1e-24
Identities = 68/233 (29%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
HG + SP +P YP + W + H + ++E Q C YD + IYDG S
Sbjct: 1860 HGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIH 1919
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST--------------AC 480
+ +G +CG++ ++ N + F SD S+ KGFL AC
Sbjct: 1920 ARLIGAYCGTQTESF-SSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGAC 1978
Query: 481 GGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYD 540
GG+L + L+S ++Y +R DC W I+AP + V+L L+ ++E C YD
Sbjct: 1979 GGFLRTGDAPVFLFSPG--WPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYD 2035
Query: 541 YVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+ + CG ++P I ST E + +RF +D S+ GF+AS+
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 111 bits (267), Expect = 7e-24
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
K ++ C +T GTI SP +P YP +C W P H I L+F F LE H
Sbjct: 924 KFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 983
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS- 477
C D++ +YD S +LG +CG +P + +S N + +VF +D + +GFL +
Sbjct: 984 NCTNDYLEVYDTDSE--TSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEA 1041
Query: 478 -TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
+A L + ++ + +N Y + +C + I + + F F LE
Sbjct: 1042 ISAATACLQDYTDDLGTFTSPNFPNN-YPNNWECIYRITVRTGQLIAVHFTNFSLEEAIG 1100
Query: 537 CRY-DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSA 591
Y D++++ F G +PP I+S S L ++F++D GFSA
Sbjct: 1101 NYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 107 bits (258), Expect = 9e-23
Identities = 67/225 (29%), Positives = 110/225 (48%), Gaps = 13/225 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G I SPNYP AY + C GH I L F+ F++EPH CA+D VT+ +G S +
Sbjct: 2698 GVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPES 2757
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGG-YLSATEEVK 491
+G +CG+ P + + NQ+ + F SD S+Q GF AT +T CGG + S ++
Sbjct: 2758 PIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIR 2817
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFEL--EREANCRYDYVQVFX-XX 548
+ + +N SR C W ++ ++++F L + C+ +V+V+
Sbjct: 2818 SPHWPQNFPEN---SR--CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
T CG P +++ S F++ ++ +GFSAS+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPA-QGFSASF 2916
Score = 104 bits (249), Expect = 1e-21
Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%)
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDG 430
V +G + S YP Y + C W T G+ + F F+LE H C+ D++ +YDG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343
Query: 431 ASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYLSATE 488
+ +G +CG LP + +++ ++ +DG +R KGF + CGG LS
Sbjct: 1344 P----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGAT 1399
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXX 548
+S + N Y +C W I ++LT F++E + C +D ++++
Sbjct: 1400 GS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGP 1455
Query: 549 XXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 1456 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 103 bits (248), Expect = 1e-21
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 12/236 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2511
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 2512 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2571
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTFELEREANCRY 539
G L T E + S G Y +C+W + P N + + F F LE +C++
Sbjct: 2572 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQF 2630
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMP--PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D ++ F CG P P ++ S+ + + F T++ + GF A Y
Sbjct: 2631 DVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKY 2684
Score = 103 bits (246), Expect = 3e-21
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 9/227 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P G +F P + + CV+ G +I++ F EL+ + + +++
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG + LG CG+ + + N +++ FK D SV++ F A + ACG L+
Sbjct: 768 VRDGETL----LGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 823
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
++ + + N Y C W I P++ + L F FE+ A+C DYV++
Sbjct: 824 EGVIR-----SPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGS 878
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG +P I S L V F S GF A +
Sbjct: 879 SSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF 925
Score = 101 bits (241), Expect = 1e-20
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 15/277 (5%)
Query: 323 DVDECAEN---NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIF 379
+++EC N NGG C + + + C C +T + C ++ +G+
Sbjct: 432 NINECLSNPCLNGGT---CVDGVDSFSCECTRLWT--GALCQVPQQVCGESLSGINGSFS 486
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLG 439
+ Y +C W T G +++ F F LE C ++ + +YDG S+ LG
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLG 546
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA---THSTACGGYLSATEEVKHLYSH 496
FCGS LPH +++S N +Y S+ +GF T CGG L T + S
Sbjct: 547 RFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGIL--TGPYGSIKSP 604
Query: 497 ARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
G+ Y DC W + + V TF T LE +C DY+++
Sbjct: 605 GYPGN--YPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLG 662
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FC P + +T + F +D + +GF +Y
Sbjct: 663 KFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 1577 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 1634
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 1635 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 1694
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 1695 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 1738
Score = 100 bits (239), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 1738 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVE 1797
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 1798 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 1853
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 1854 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1913
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 1914 DGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 2161 ICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 2220
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 2221 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 2280
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 2281 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 2335
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 10/220 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D G + SP +P Y KDC + H I L F+ +E EC D +
Sbjct: 3395 CNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLE 3454
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF--LATHS-TACGGY 483
+ +G++++ LG +CG+ LP+ V + N++Y+ FKSD +G+ + T S + CGG
Sbjct: 3455 VRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGT 3514
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L + ++ Y Y + C+W + AP V + F ++ +C +Y+
Sbjct: 3515 LYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570
Query: 544 VFXXXXXXXXXXXTFCG--IKMPPEIVSTSEALLVRFRTD 581
++ +CG + P V++S + ++F D
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAP-FVASSNQVFIKFHAD 3609
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 1347 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 1405
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 1406 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 1465
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 1466 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 1513
Score = 97.1 bits (231), Expect = 2e-19
Identities = 60/226 (26%), Positives = 106/226 (46%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 2049
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 2050 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 2106
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ +
Sbjct: 2107 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPP 2165
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 2166 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 2211
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 2036
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 2037 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 2096
Query: 169 SIDHG 173
D G
Sbjct: 2097 HADRG 2101
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/157 (36%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDI----EVDSNGHL 62
LGR CG P + S+G+ L +V+ L + GF YEA+ D G
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLA-YEGFLINYEAISAATACLQDYTDDLGTF 1059
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY-DKVKVRDGDSMDSPL 121
SPN+P++Y N CI++++V +A+ F +F +E Y D +++RDG SPL
Sbjct: 1060 TSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPL 1119
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSA 158
+G+F G +PP I S SNKL + F+SD ++GFSA
Sbjct: 1120 LGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 95.5 bits (227), Expect = 5e-19
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Query: 9 RLCGSGKG--PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPN 66
+ CG P+ S+ S V+++ G+ + R + A C D + G+L SP
Sbjct: 3352 QFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYH-KAFGNLRSPG 3410
Query: 67 YPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFC 126
+PD+Y +K C L+ PQ++ ++L FHS +EN C D ++VR+G + +SPL+G +C
Sbjct: 3411 WPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYC 3470
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG 173
G +P + S +N+L + F+SDS G+ + C +G
Sbjct: 3471 GTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGTLYG 3517
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 1689 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 1746
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 1805
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 1806 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 1851
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 2173 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 2231
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 2232 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 2291
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 2292 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 2331
Score = 92.3 bits (219), Expect = 5e-18
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 13/235 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ----ECAY 422
C + T P G I SPNYP Y +C + P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-TACG 481
D V I G S CG ++P + + + F S+ + GF ++ +CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMP-APLTIAGPVLLNFYSNEQITDFGFKFSYRIISCG 3038
Query: 482 GYLSATEEV--KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
G + + + YS+A Y ++ + C + I + ++L F F++ +C +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMH-----CLYTITVSDDKVIELKFSDFDVVPSTSCSH 3093
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+ ++ FCG K PP + S++ ++L+ F+TD KG+ S++
Sbjct: 3094 DYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR 3148
Score = 91.9 bits (218), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
LGR CGS + S+ + L +Y LR RGF +E CGG I G +
Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLR--NGRGFTVRWETQQPECGG-ILTGPYGSI 601
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
+SP YP +Y P + C+W + D V F + +E+HD C+ D +++RDG PL+
Sbjct: 602 KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLL 661
Query: 123 GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
G FC P +++T + F SDS + GF T++
Sbjct: 662 GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700
Score = 91.9 bits (218), Expect = 6e-18
Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 13/167 (7%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV------CGGDIEVDS 58
P+LG+ CGS + P ++S+ + + +V++ + +G++ + CGG + S
Sbjct: 3107 PLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTAKGWKMSFRQTLGPQQGCGGYL-TGS 3164
Query: 59 NGHLESPNYPDD--YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT---CSYDKVKVRD 113
N SP+ + Y N C+W + P + + L F++F +E T C YD VK+ D
Sbjct: 3165 NNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYD 3224
Query: 114 GDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
GDS ++ L G FCG +P S+ N L V F SD T+++ GF+AT+
Sbjct: 3225 GDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 352 GFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV 411
GFT+ + + ++ C +T P+G+I SP YP YP +DCVW T+P + F
Sbjct: 578 GFTV---RWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634
Query: 412 FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKG 471
LE H +C D++ I DG LG FC + + + + F SD + +G
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 694
Query: 472 FLATHSTA-----CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
F T+ T+ CGG + T+ L+ G + C + ++ P+ +++ F
Sbjct: 695 FHITYLTSPSDLRCGG--NYTDPEGELFLPELSGP--FTHTRQCVYMMKQPQGEQIQINF 750
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
EL+ +++ +Y++V CG I S + ++ +RF+ D S+
Sbjct: 751 THVELQCQSDSSQNYIEV----RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEK 806
Query: 587 KGFSASYQM 595
F A YQ+
Sbjct: 807 ASFRAVYQV 815
Score = 89.0 bits (211), Expect = 4e-17
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNG 60
+P+LG GS P + S ++L + ++ ++ GF A+++ CGG++ S+G
Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSD-QIDTRSGFSAYWDGSSTGCGGNLTT-SSG 1174
Query: 61 HLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
SPNYP Y + C W L L F F +E+H C+ D + V DG S +S
Sbjct: 1175 TFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSH 1234
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+ CG + PP IRS+ + + + +D Q GF A +
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 2289 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 2346
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 2347 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 2405
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 2406 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 2452
Score = 87.8 bits (208), Expect = 1e-16
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVE 99
GF+ Y + G + S+G + SP Y PN + C++ ++V D + L+F F+V
Sbjct: 3027 GFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV 3086
Query: 100 NHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSAT 159
+CS+D + + DG + PL+G FCG K PP+++S++N +L++F++DS G+ +
Sbjct: 3087 PSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146
Query: 160 F 160
F
Sbjct: 3147 F 3147
Score = 86.2 bits (204), Expect = 3e-16
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESP 65
+LG++CG+G ++S + + + ++ ++ FRA Y+ CG E+ G + SP
Sbjct: 774 LLGKVCGNGTISHIKSITNSVWIRFKIDASVEK-ASFRAVYQVACGD--ELTGEGVIRSP 830
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y + C W + PQ + L F FE+ + C D V++ + SP +
Sbjct: 831 FFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY 890
Query: 126 CGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
CG IP I S N L V F S+ + GF A F E C I
Sbjct: 891 CGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 1619 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 1674
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 1675 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
Query: 323 DVDEC 327
V C
Sbjct: 1734 SVSAC 1738
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA--VCGGDIEVDSNGH 61
+P + CG+ + S + L V + + H GF A + A + G+I +S G
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENH-GFMAKFSAEDLACGEILTESTGT 942
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
++SP +P+ Y C W + V ++ + L F +F +E H C+ D ++V D DS S
Sbjct: 943 IQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-- 1000
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG IPP + S+ N L+++F +DS + GF
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 1035
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 86/164 (52%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 1517
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V ++++V L F F++E D+C + DG S
Sbjct: 1518 S-GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSS 1572
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 1573 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 82.2 bits (194), Expect = 5e-15
Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-GHLES 64
+L +LCG K P++RS+G + + + + RGF+A Y C + V+ G LES
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTD-EGQQGRGFKAEYRQTCENVVIVNQTYGILES 1293
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGM 124
YP+ Y N+ C W + V F +F++E+H CS D +++ DG +G
Sbjct: 1294 IGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1349
Query: 125 FCGHKIPPDIRSTSNKLLVIFESD 148
+CG +PP +TS+KL V+ +D
Sbjct: 1350 YCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 81.8 bits (193), Expect = 7e-15
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 203 ENACGGALYGPNGTITSPSFPE--LYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+ CGG L G N T SP +Y NC+W I+AP I L F F LE +
Sbjct: 3154 QQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST-R 3212
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
Q C YD V ++ ++ G FCG+ +P P S G+ L VQF SD ++ R GF A Y
Sbjct: 3213 QRCLYDYVKLYDG-DSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 321 YI 322
I
Sbjct: 3272 TI 3273
Score = 81.4 bits (192), Expect = 9e-15
Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W IV+ P +R+ L+F F LE + Q+C
Sbjct: 1736 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS----QDC 1791
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 1792 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1847
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 2406 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 2463
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 2464 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 2523
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 2524 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Score = 79.8 bits (188), Expect = 3e-14
Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 16/184 (8%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 2576
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQ--DYQVALRFHSFEVENHDTCSYDKVKVR 112
G+ SP Y +Y N C W LS P + +++ F F +E+H C +D ++ R
Sbjct: 2577 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFR 2636
Query: 113 DGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
GD+ D PL+ CG P + +++ + F ++ V+ GF A + F +C I
Sbjct: 2637 VGDA-DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY--SFTDCGGIQ 2693
Query: 172 HGCS 175
G S
Sbjct: 2694 IGDS 2697
Score = 79.4 bits (187), Expect = 4e-14
Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 9/137 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG G +G ITSP++P Y L +C + AP H ITL F+ FD+E + C +
Sbjct: 2689 CGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPH----TTCAW 2744
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
DSVTV + G+ G +CG + P + S + L V F SD S+ GF A +
Sbjct: 2745 DSVTVRNG-GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTL 2803
Query: 326 ECAENNGGCQHECHNTL 342
C GG H + T+
Sbjct: 2804 GC----GGIFHSDNGTI 2816
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/238 (25%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP--HQECAYD 423
GC +GTI SP++P +P C W T +++ F+ L P +C
Sbjct: 2804 GCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNS 2863
Query: 424 HVTIYDGA-SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
V ++ G D L CG+ P V+ N VF+S +GF A+ + CG
Sbjct: 2864 FVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCGS 2922
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA----NCR 538
+ Y + Y++ +C + IEA V LTF++F LE + +C
Sbjct: 2923 NFTGPSG----YIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2978
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
D V + T CG +MP + LL F +++ + GF SY+++
Sbjct: 2979 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLL-NFYSNEQITDFGFKFSYRII 3035
Score = 75.8 bits (178), Expect = 4e-13
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G+I SP +P YPP ++C+W +V P +T F LE + +C
Sbjct: 590 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLE----HHDDCNK 645
Query: 266 DSVTVH-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + L D L G FC T PP+ + G R+ F SD + GF Y
Sbjct: 646 DYLEIRDGPLYQDPLL--GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 1842 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 1901
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 1902 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 74.9 bits (176), Expect = 8e-13
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L GTI SP P +YP NC W I+ P H I L F F LE + C
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE----FHYNCT 986
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + V+ D G +CG ++PP +TS G+ L + F +D + GF Y
Sbjct: 987 NDYLEVYD---TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 2205 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 2262
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 2263 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 2317
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 2318 SDNSPTHVGFKAKYSI 2333
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFY-----EAVCGGDIEVDSN 59
P+LG+ C + P +++TG + + ++ +GF Y + CGG+ D
Sbjct: 659 PLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISD-QGFHITYLTSPSDLRCGGNY-TDPE 716
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L P + + C++ + PQ Q+ + F E++ S + ++VRDG++
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET--- 773
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+G CG+ I+S +N + + F+ D++V+KA F A +
Sbjct: 774 -LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Query: 2 PDAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDS 58
P++P++G+ CG+ ++S ++L V + L+ GF A + CGG D
Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATWNTQTLGCGGIFHSD- 2812
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHD-TCSYDKVKVRDG-D 115
NG + SP++P ++ N C W + + + F ++F + + D C VKV G +
Sbjct: 2813 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
+D L+ CG+ P + + SN +F+S + GFSA+F+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASFV 2917
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
G ++ T I SPN C W + P ++K+ +L Q+C +++
Sbjct: 3279 GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTS-QDCTQNYL 3337
Query: 426 TIYDGASADVKTLGIFCG---SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ D + FCG S +P + +S + ++FKS G V R ++
Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVP-VFYSSMSTAMVIFKS-GVVNRNSRMSFTYQIADC 3395
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ +L S + DN Y++ DC + AP+NH + L F + +E CR D++
Sbjct: 3396 NRDYHKAFGNLRSPG-WPDN-YDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFL 3453
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+V +CG +P + S + L +RF++D +G+
Sbjct: 3454 EVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 68.9 bits (161), Expect = 5e-11
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L G G I SP FP +YP + C W I P I LNFT F++ + CE
Sbjct: 816 ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSS----AHCE 870
Query: 265 YDSVTVHSK--LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D V + S LG+ ++ +CGT +P +TS + L V F S GF A +
Sbjct: 871 TDYVEIGSSSILGSPENKK---YCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Query: 323 DVDEC----AENNGGCQHECHNTLGGYECACHSGFTLHPN 358
+ C E+ G Q H + + C + PN
Sbjct: 928 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPN 967
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 1446
Query: 266 DSVTVHSKLGADV-LRRHGAFC---GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 1447 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 1504
Query: 322 IDVDEC 327
C
Sbjct: 1505 AVTGGC 1510
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 2047 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 2104
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 2105 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSP 2164
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 2165 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 2031
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 2032 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSN 59
++P+LG+ CG+ + S + L + ++ + RG+ + + CGG + D
Sbjct: 3462 NSPLLGKYCGTLLPNPVFSQNNELYLRFKSD-SVTSDRGYEIIWTSSPSGCGGTLYGD-R 3519
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YP Y N C W L P V + F+ +++ C + + + DG + S
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASS 3579
Query: 120 PLIGMFCG--HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P G +CG I P + S SN++ + F +D + + F T+
Sbjct: 3580 PSSGPYCGGDTSIAPFVAS-SNQVFIKFHADYARRPSAFRLTW 3621
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEP----QDSC-- 1563
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 1564 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 2507
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 2508 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 2568 AVCGGSLPNTPEGNFTSPGYD 2588
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG GP+G I SP++P+ Y NC + I A P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 266 DSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D VH G V+ CG +P P+T G VL + F S+ + GF Y I
Sbjct: 2980 DG--VHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRI 3034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 190 DIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFT 249
D GYE+ + CGG LYG G+ TSP +P YP C W +VAP +T+NF
Sbjct: 3497 DRGYEIIWTSSP--SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFY 3554
Query: 250 HFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCG--TALPPPVTSDGSVLRVQFTS 307
++ +C + +T++ A G +CG T++ P V S V ++F +
Sbjct: 3555 FISIDD----PGDCVQNYLTLYDGPNAS-SPSSGPYCGGDTSIAPFVASSNQVF-IKFHA 3608
Query: 308 DGSVHRSGF 316
D + S F
Sbjct: 3609 DYARRPSAF 3617
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 2336 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 2391
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 2392 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2448
Query: 324 VDEC 327
++EC
Sbjct: 2449 MEEC 2452
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC + G+ SP YP YP C W G + + F ++ +C +++
Sbjct: 3510 GCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYL 3569
Query: 426 TIYDGASADVKTLGIFCGSKLPHL-VMASQNQMYMVFKSDGSVQRKGFLAT 475
T+YDG +A + G +CG +AS NQ+++ F +D + + F T
Sbjct: 3570 TLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLT 3620
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+ VCG + NG + Y + C W + + + F F +E+ D C +
Sbjct: 471 QQVCGESLS-GINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ ++V DGDS + +G FCG +P ++ S+ N L S+ GF+ + + E
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589
Query: 167 CASI 170
C I
Sbjct: 590 CGGI 593
Score = 57.6 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D +L CG+ GP++ + + T V+Q + P +GF A + + CG + S G+
Sbjct: 2875 DKALLATGCGNVAPGPVITPSNT-FTAVFQS--QEAPAQGFSASFVSRCGSNFTGPS-GY 2930
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSM 117
+ SPNYP Y N C + + V L F SF +E +C D V + G S+
Sbjct: 2931 IISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSV 2990
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S CG ++P + + + +L+ F S+ + GF ++
Sbjct: 2991 MSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 3032
Score = 56.0 bits (129), Expect = 4e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CG LS + +S+ R D Y +C W I+ +++TF F LE NC +
Sbjct: 474 CGESLSG---INGSFSY-RSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
+++QV+ FCG +P E++S+ AL ++ +GF+ ++ +P
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 588
Score = 55.2 bits (127), Expect = 7e-07
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD-S 58
+A + G CGS S+G+ LTV + L L+ GF A Y + CGG +
Sbjct: 3229 NANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE-REGFNATYTIMDMPCGGTYNATWT 3287
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
++ SPN D P +C W + P QV + + ++ + D C+ + ++++D
Sbjct: 3288 PQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGH 3346
Query: 119 SPLIGMFCGHKIP--PDIRSTSNKLLVIFESDSTVQKAGFSATF 160
FCG P S+ + +VIF+S + + S T+
Sbjct: 3347 GNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTY 3390
Score = 54.4 bits (125), Expect = 1e-06
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ ++ + AC GT TSP+FP YP C++ I I ++FT+F
Sbjct: 1034 GFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
Query: 252 DLE---GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
LE GN+ Y G + G F G+ LPP + S + L ++F SD
Sbjct: 1094 SLEEAIGNY-------YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSD 1146
Query: 309 GSVHRSGFAAVYYIDVDECAEN 330
RSGF+A + C N
Sbjct: 1147 QIDTRSGFSAYWDGSSTGCGGN 1168
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP +P+ Y K+C + AP H I+L F +E + EC D + V +
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENS----VECRNDFLEVRNGS 3459
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
++ G +CGT LP PV S + L ++F SD G+ ++ C
Sbjct: 3460 NSNSPLL-GKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGC 3511
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 1856 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 1911
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT +S G+ L F SD S+ GF ++
Sbjct: 1912 IYD--GPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 7/129 (5%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ + DG CGG L +GT SP++P Y C W + + L F F
Sbjct: 1153 GFSAYWDGSS--TGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDF 1210
Query: 252 DLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
LE + C D + V+ ++ CG PP + S G + ++ +D
Sbjct: 1211 HLE----HHPNCTLDYLAVYDGPSSN-SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ 1265
Query: 312 HRSGFAAVY 320
GF A Y
Sbjct: 1266 QGRGFKAEY 1274
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + S +P Y ++C W I A + + F FDLE +H+ C D + ++
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLE-HHI---NCSTDYLELY--- 1341
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 1342 --DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 1388
Score = 48.8 bits (111), Expect = 6e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 205 ACGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+CGG +G ITSP++ YP +CL+ I I L F+ FD+ + C
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV----VPSTSC 3091
Query: 264 EYDSVTVHSKLG-ADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
+D + ++ +D L G FCG+ PP V S + + + F +D
Sbjct: 3092 SHDYLAIYDGANTSDPLL--GKFCGSKRPPNVKSSNNSMLLVFKTD 3135
Score = 48.4 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE---NACGGALYGPNGTIT 218
+ +EC S +CV+ + + C C + G C+ CG +L G NG+ +
Sbjct: 431 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWT----GALCQVPQQVCGESLSGINGSFS 486
Query: 219 SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADV 278
S Y NC W I + + FT F LE C ++ + V+ +
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLES----MDNCPHEFLQVYDGDSSSA 542
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
+ G FCG++LP + S + L S+ + GF + EC
Sbjct: 543 FQL-GRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC 590
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + NGTI SP +P+ +P C W + + ++F + L + Q + +
Sbjct: 2805 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
V ++ L G CG P PV + + F S GF+A + V
Sbjct: 2865 VKVWAGTEEVDKALLATG--CGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF---VS 2918
Query: 326 ECAENNGG 333
C N G
Sbjct: 2919 RCGSNFTG 2926
Score = 46.4 bits (105), Expect = 3e-04
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P G + P + + C++ + P +I +NFTH +L +C+
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVEL--------QCQS 759
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
DS + ++ D G CG + S + + ++F D SV ++ F AVY +
Sbjct: 760 DSSQNYIEV-RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815
Score = 33.5 bits (73), Expect = 2.4
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 5/36 (13%)
Query: 323 DVDECAENNGGCQ----HECHNTLGGYEC-ACHSGF 353
D++EC NNGGC EC NT G C AC G+
Sbjct: 305 DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 340
>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 3623
Score = 140 bits (340), Expect = 1e-32
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 1508 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC---- 1563
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 1564 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 1623
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 1624 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 1679
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 1727
Score = 139 bits (336), Expect = 3e-32
Identities = 109/398 (27%), Positives = 172/398 (43%), Gaps = 50/398 (12%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 264 EYDSVTVHSKLGADVL---RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+Y + + + L +G FCG+ + + + + VQF SD S GF Y
Sbjct: 2151 DYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Query: 321 YIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFS 380
C GG + H+ A +G+ PN PH
Sbjct: 2211 EAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH----- 2239
Query: 381 PNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKTLG 439
NYP DC+W + P RI+L F + F++E C +++ + DG +D L
Sbjct: 2240 -NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPILS 2294
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSHAR 498
FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 2295 KFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPT 2354
Query: 499 --YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 2355 LPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNILG 2408
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 2409 RYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 2446
Score = 135 bits (327), Expect = 4e-31
Identities = 80/231 (34%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G I SP Y A YP C++ + + I+L F+ F++ P C++D++ IYDGA+
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTS 3105
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF-LATHST-----ACGGYLSATE 488
LG FCGSK P V +S N M +VFK+D KG+ ++ T CGGYL+ +
Sbjct: 3106 DPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSN 3165
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA---NCRYDYVQVF 545
S + Y+ +C W I AP N + LTF TF LE + C YDYV+++
Sbjct: 3166 NT--FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLY 3223
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
TFCG +P +S+ L V+F +D +L +GF+A+Y ++
Sbjct: 3224 DGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3274
Score = 132 bits (318), Expect = 5e-30
Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
SGF+ + D GC ++T GT SPNYP Y +C W ++ G +L F
Sbjct: 1152 SGFSAY---WDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFK 1208
Query: 411 VFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRK 470
F LE H C D++ +YDG S++ L CG + P L+ +S + M++ ++D Q +
Sbjct: 1209 DFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGR 1268
Query: 471 GFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFE 530
GF A + C + + L S N Y C+W I A + V TFL F+
Sbjct: 1269 GFKAEYRQTCENVVIVNQTYGILESIGY--PNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326
Query: 531 LEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
LE NC DY++++ +CG+ +PP +TS L V TD
Sbjct: 1327 LEHHINCSTDYLELY----DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 124 bits (298), Expect = 1e-27
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 8/232 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY-DHV 425
C D T GT SPN+P YP +C+++ + G I + F F LE Y D +
Sbjct: 1048 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFL 1107
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLAT---HSTACGG 482
I DG LGIF GS LP +++ N++++ FKSD R GF A ST CGG
Sbjct: 1108 EIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGG 1167
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L+ + + Y Y S ++C W +++ +L F F LE NC DY+
Sbjct: 1168 NLTTSSGT---FISPNYPMPYYHS-SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1223
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
V+ CG + PP I S+ +++ ++ RTD+ +GF A Y+
Sbjct: 1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1275
Score = 123 bits (297), Expect = 2e-27
Identities = 64/171 (37%), Positives = 97/171 (56%), Gaps = 2/171 (1%)
Query: 3 DAPVLGRLCGSGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D P++ RLCG K + + S++ + + R++ H GF A Y G I++ +G
Sbjct: 2641 DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVE-HIGFHAKYSFTDCGGIQIGDSGV 2699
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
+ SPNYP+ Y C L PQ + + L F F++E H TC++D V VR+G S +SP+
Sbjct: 2700 ITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPI 2759
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH 172
IG +CG+ P I+S SN+L+V F SD ++Q GF AT+ + C I H
Sbjct: 2760 IGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFH 2810
Score = 121 bits (292), Expect = 7e-27
Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T G I SP +P YP + C W I L F VFE+ C D+V
Sbjct: 817 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGGY 483
I + +CG+ +P + + N +Y+ F S + GF+A S ACG
Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L TE + S N Y +C W+I NH + L F TF LE NC DY++
Sbjct: 936 L--TESTGTIQSPGH--PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991
Query: 544 VFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
V+ +CG +PP + S+ +L++ F TD L ++GF +Y+ +
Sbjct: 992 VYDTDSETSLGR--YCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 1042
Score = 118 bits (283), Expect = 8e-26
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 1742
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 1743 YMAEGI---FNSPGYPD-IYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEI 1798
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 1799 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 1850
Score = 115 bits (276), Expect = 6e-25
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 1390 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 1449
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 1450 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 1509
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I RNH V L F F+LE + +C
Sbjct: 1510 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC-- 1563
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 1564 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1617
Score = 114 bits (274), Expect = 1e-24
Identities = 68/233 (29%), Positives = 107/233 (45%), Gaps = 18/233 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
HG + SP +P YP + W + H + ++E Q C YD + IYDG S
Sbjct: 1860 HGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIYDGPSIH 1919
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST--------------AC 480
+ +G +CG++ ++ N + F SD S+ KGFL AC
Sbjct: 1920 ARLIGAYCGTQTESF-SSTGNSLTFHFYSDSSISGKGFLLEWFAVDAPDGVLPTIAPGAC 1978
Query: 481 GGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYD 540
GG+L + L+S ++Y +R DC W I+AP + V+L L+ ++E C YD
Sbjct: 1979 GGFLRTGDAPVFLFSPG--WPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYD 2035
Query: 541 YVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+ + CG ++P I ST E + +RF +D S+ GF+AS+
Sbjct: 2036 SLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Score = 111 bits (267), Expect = 7e-24
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
K ++ C +T GTI SP +P YP +C W P H I L+F F LE H
Sbjct: 924 KFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 983
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS- 477
C D++ +YD S +LG +CG +P + +S N + +VF +D + +GFL +
Sbjct: 984 NCTNDYLEVYDTDSE--TSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEA 1041
Query: 478 -TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
+A L + ++ + +N Y + +C + I + + F F LE
Sbjct: 1042 ISAATACLQDYTDDLGTFTSPNFPNN-YPNNWECIYRITVRTGQLIAVHFTNFSLEEAIG 1100
Query: 537 CRY-DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSA 591
Y D++++ F G +PP I+S S L ++F++D GFSA
Sbjct: 1101 NYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 107 bits (258), Expect = 9e-23
Identities = 67/225 (29%), Positives = 110/225 (48%), Gaps = 13/225 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G I SPNYP AY + C GH I L F+ F++EPH CA+D VT+ +G S +
Sbjct: 2698 GVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPES 2757
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGG-YLSATEEVK 491
+G +CG+ P + + NQ+ + F SD S+Q GF AT +T CGG + S ++
Sbjct: 2758 PIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIR 2817
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFEL--EREANCRYDYVQVFX-XX 548
+ + +N SR C W ++ ++++F L + C+ +V+V+
Sbjct: 2818 SPHWPQNFPEN---SR--CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
T CG P +++ S F++ ++ +GFSAS+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPA-QGFSASF 2916
Score = 104 bits (249), Expect = 1e-21
Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%)
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDG 430
V +G + S YP Y + C W T G+ + F F+LE H C+ D++ +YDG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343
Query: 431 ASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYLSATE 488
+ +G +CG LP + +++ ++ +DG +R KGF + CGG LS
Sbjct: 1344 P----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGAT 1399
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXX 548
+S + N Y +C W I ++LT F++E + C +D ++++
Sbjct: 1400 GS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGP 1455
Query: 549 XXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 1456 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 103 bits (248), Expect = 1e-21
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 12/236 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2511
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 2512 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2571
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTFELEREANCRY 539
G L T E + S G Y +C+W + P N + + F F LE +C++
Sbjct: 2572 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQF 2630
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMP--PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D ++ F CG P P ++ S+ + + F T++ + GF A Y
Sbjct: 2631 DVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKY 2684
Score = 103 bits (246), Expect = 3e-21
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 9/227 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P G +F P + + CV+ G +I++ F EL+ + + +++
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG + LG CG+ + + N +++ FK D SV++ F A + ACG L+
Sbjct: 768 VRDGETL----LGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 823
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
++ + + N Y C W I P++ + L F FE+ A+C DYV++
Sbjct: 824 EGVIR-----SPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGS 878
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG +P I S L V F S GF A +
Sbjct: 879 SSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF 925
Score = 101 bits (241), Expect = 1e-20
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 15/277 (5%)
Query: 323 DVDECAEN---NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIF 379
+++EC N NGG C + + + C C +T + C ++ +G+
Sbjct: 432 NINECLSNPCLNGGT---CVDGVDSFSCECTRLWT--GALCQVPQQVCGESLSGINGSFS 486
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLG 439
+ Y +C W T G +++ F F LE C ++ + +YDG S+ LG
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLG 546
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA---THSTACGGYLSATEEVKHLYSH 496
FCGS LPH +++S N +Y S+ +GF T CGG L T + S
Sbjct: 547 RFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGIL--TGPYGSIKSP 604
Query: 497 ARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
G+ Y DC W + + V TF T LE +C DY+++
Sbjct: 605 GYPGN--YPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLG 662
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FC P + +T + F +D + +GF +Y
Sbjct: 663 KFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 1577 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 1634
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 1635 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 1694
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 1695 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 1738
Score = 100 bits (239), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 1738 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVE 1797
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 1798 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 1853
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 1854 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1913
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 1914 DGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 2161 ICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 2220
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 2221 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 2280
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 2281 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 2335
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 10/220 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D G + SP +P Y KDC + H I L F+ +E EC D +
Sbjct: 3395 CNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLE 3454
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF--LATHS-TACGGY 483
+ +G++++ LG +CG+ LP+ V + N++Y+ FKSD +G+ + T S + CGG
Sbjct: 3455 VRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGT 3514
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L + ++ Y Y + C+W + AP V + F ++ +C +Y+
Sbjct: 3515 LYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570
Query: 544 VFXXXXXXXXXXXTFCG--IKMPPEIVSTSEALLVRFRTD 581
++ +CG + P V++S + ++F D
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAP-FVASSNQVFIKFHAD 3609
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 1347 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 1405
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 1406 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 1465
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 1466 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 1513
Score = 97.1 bits (231), Expect = 2e-19
Identities = 60/226 (26%), Positives = 106/226 (46%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 2049
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 2050 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 2106
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ +
Sbjct: 2107 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSPP 2165
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 2166 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 2211
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 2036
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 2037 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 2096
Query: 169 SIDHG 173
D G
Sbjct: 2097 HADRG 2101
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/157 (36%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDI----EVDSNGHL 62
LGR CG P + S+G+ L +V+ L + GF YEA+ D G
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLA-YEGFLINYEAISAATACLQDYTDDLGTF 1059
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY-DKVKVRDGDSMDSPL 121
SPN+P++Y N CI++++V +A+ F +F +E Y D +++RDG SPL
Sbjct: 1060 TSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPL 1119
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSA 158
+G+F G +PP I S SNKL + F+SD ++GFSA
Sbjct: 1120 LGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 95.5 bits (227), Expect = 5e-19
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Query: 9 RLCGSGKG--PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPN 66
+ CG P+ S+ S V+++ G+ + R + A C D + G+L SP
Sbjct: 3352 QFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYH-KAFGNLRSPG 3410
Query: 67 YPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFC 126
+PD+Y +K C L+ PQ++ ++L FHS +EN C D ++VR+G + +SPL+G +C
Sbjct: 3411 WPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYC 3470
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG 173
G +P + S +N+L + F+SDS G+ + C +G
Sbjct: 3471 GTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGTLYG 3517
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 1689 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 1746
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 1805
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 1806 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 1851
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 2173 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 2231
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 2232 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 2291
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 2292 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 2331
Score = 92.3 bits (219), Expect = 5e-18
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 13/235 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ----ECAY 422
C + T P G I SPNYP Y +C + P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-TACG 481
D V I G S CG ++P + + + F S+ + GF ++ +CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMP-APLTIAGPVLLNFYSNEQITDFGFKFSYRIISCG 3038
Query: 482 GYLSATEEV--KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
G + + + YS+A Y ++ + C + I + ++L F F++ +C +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMH-----CLYTITVSDDKVIELKFSDFDVVPSTSCSH 3093
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+ ++ FCG K PP + S++ ++L+ F+TD KG+ S++
Sbjct: 3094 DYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR 3148
Score = 91.9 bits (218), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
LGR CGS + S+ + L +Y LR RGF +E CGG I G +
Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLR--NGRGFTVRWETQQPECGG-ILTGPYGSI 601
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
+SP YP +Y P + C+W + D V F + +E+HD C+ D +++RDG PL+
Sbjct: 602 KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLL 661
Query: 123 GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
G FC P +++T + F SDS + GF T++
Sbjct: 662 GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700
Score = 91.9 bits (218), Expect = 6e-18
Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 13/167 (7%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV------CGGDIEVDS 58
P+LG+ CGS + P ++S+ + + +V++ + +G++ + CGG + S
Sbjct: 3107 PLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTAKGWKMSFRQTLGPQQGCGGYL-TGS 3164
Query: 59 NGHLESPNYPDD--YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT---CSYDKVKVRD 113
N SP+ + Y N C+W + P + + L F++F +E T C YD VK+ D
Sbjct: 3165 NNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYD 3224
Query: 114 GDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
GDS ++ L G FCG +P S+ N L V F SD T+++ GF+AT+
Sbjct: 3225 GDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 352 GFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV 411
GFT+ + + ++ C +T P+G+I SP YP YP +DCVW T+P + F
Sbjct: 578 GFTV---RWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634
Query: 412 FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKG 471
LE H +C D++ I DG LG FC + + + + F SD + +G
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 694
Query: 472 FLATHSTA-----CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
F T+ T+ CGG + T+ L+ G + C + ++ P+ +++ F
Sbjct: 695 FHITYLTSPSDLRCGG--NYTDPEGELFLPELSGP--FTHTRQCVYMMKQPQGEQIQINF 750
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
EL+ +++ +Y++V CG I S + ++ +RF+ D S+
Sbjct: 751 THVELQCQSDSSQNYIEV----RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEK 806
Query: 587 KGFSASYQM 595
F A YQ+
Sbjct: 807 ASFRAVYQV 815
Score = 89.0 bits (211), Expect = 4e-17
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNG 60
+P+LG GS P + S ++L + ++ ++ GF A+++ CGG++ S+G
Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSD-QIDTRSGFSAYWDGSSTGCGGNLTT-SSG 1174
Query: 61 HLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
SPNYP Y + C W L L F F +E+H C+ D + V DG S +S
Sbjct: 1175 TFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSH 1234
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+ CG + PP IRS+ + + + +D Q GF A +
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 2289 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 2346
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 2347 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 2405
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 2406 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 2452
Score = 87.8 bits (208), Expect = 1e-16
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVE 99
GF+ Y + G + S+G + SP Y PN + C++ ++V D + L+F F+V
Sbjct: 3027 GFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV 3086
Query: 100 NHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSAT 159
+CS+D + + DG + PL+G FCG K PP+++S++N +L++F++DS G+ +
Sbjct: 3087 PSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146
Query: 160 F 160
F
Sbjct: 3147 F 3147
Score = 86.2 bits (204), Expect = 3e-16
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESP 65
+LG++CG+G ++S + + + ++ ++ FRA Y+ CG E+ G + SP
Sbjct: 774 LLGKVCGNGTISHIKSITNSVWIRFKIDASVEK-ASFRAVYQVACGD--ELTGEGVIRSP 830
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y + C W + PQ + L F FE+ + C D V++ + SP +
Sbjct: 831 FFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY 890
Query: 126 CGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
CG IP I S N L V F S+ + GF A F E C I
Sbjct: 891 CGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 1619 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 1674
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 1675 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
Query: 323 DVDEC 327
V C
Sbjct: 1734 SVSAC 1738
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA--VCGGDIEVDSNGH 61
+P + CG+ + S + L V + + H GF A + A + G+I +S G
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENH-GFMAKFSAEDLACGEILTESTGT 942
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
++SP +P+ Y C W + V ++ + L F +F +E H C+ D ++V D DS S
Sbjct: 943 IQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-- 1000
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG IPP + S+ N L+++F +DS + GF
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 1035
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/164 (33%), Positives = 86/164 (52%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 1517
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V ++++V L F F++E D+C + DG S
Sbjct: 1518 S-GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC----IMAYDGLSS 1572
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 1573 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 82.2 bits (194), Expect = 5e-15
Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-GHLES 64
+L +LCG K P++RS+G + + + + RGF+A Y C + V+ G LES
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTD-EGQQGRGFKAEYRQTCENVVIVNQTYGILES 1293
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGM 124
YP+ Y N+ C W + V F +F++E+H CS D +++ DG +G
Sbjct: 1294 IGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1349
Query: 125 FCGHKIPPDIRSTSNKLLVIFESD 148
+CG +PP +TS+KL V+ +D
Sbjct: 1350 YCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 81.8 bits (193), Expect = 7e-15
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 203 ENACGGALYGPNGTITSPSFPE--LYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+ CGG L G N T SP +Y NC+W I+AP I L F F LE +
Sbjct: 3154 QQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST-R 3212
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
Q C YD V ++ ++ G FCG+ +P P S G+ L VQF SD ++ R GF A Y
Sbjct: 3213 QRCLYDYVKLYDG-DSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 321 YI 322
I
Sbjct: 3272 TI 3273
Score = 81.4 bits (192), Expect = 9e-15
Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W IV+ P +R+ L+F F LE + Q+C
Sbjct: 1736 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS----QDC 1791
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 1792 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1847
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 2406 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 2463
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 2464 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 2523
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 2524 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Score = 79.8 bits (188), Expect = 3e-14
Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 16/184 (8%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 2576
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQ--DYQVALRFHSFEVENHDTCSYDKVKVR 112
G+ SP Y +Y N C W LS P + +++ F F +E+H C +D ++ R
Sbjct: 2577 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFR 2636
Query: 113 DGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
GD+ D PL+ CG P + +++ + F ++ V+ GF A + F +C I
Sbjct: 2637 VGDA-DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY--SFTDCGGIQ 2693
Query: 172 HGCS 175
G S
Sbjct: 2694 IGDS 2697
Score = 79.4 bits (187), Expect = 4e-14
Identities = 49/137 (35%), Positives = 68/137 (49%), Gaps = 9/137 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG G +G ITSP++P Y L +C + AP H ITL F+ FD+E + C +
Sbjct: 2689 CGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIEPH----TTCAW 2744
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
DSVTV + G+ G +CG + P + S + L V F SD S+ GF A +
Sbjct: 2745 DSVTVRNG-GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTL 2803
Query: 326 ECAENNGGCQHECHNTL 342
C GG H + T+
Sbjct: 2804 GC----GGIFHSDNGTI 2816
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/238 (25%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP--HQECAYD 423
GC +GTI SP++P +P C W T +++ F+ L P +C
Sbjct: 2804 GCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNS 2863
Query: 424 HVTIYDGA-SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
V ++ G D L CG+ P V+ N VF+S +GF A+ + CG
Sbjct: 2864 FVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCGS 2922
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA----NCR 538
+ Y + Y++ +C + IEA V LTF++F LE + +C
Sbjct: 2923 NFTGPSG----YIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2978
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
D V + T CG +MP + LL F +++ + GF SY+++
Sbjct: 2979 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLL-NFYSNEQITDFGFKFSYRII 3035
Score = 75.8 bits (178), Expect = 4e-13
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G+I SP +P YPP ++C+W +V P +T F LE + +C
Sbjct: 590 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLE----HHDDCNK 645
Query: 266 DSVTVH-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + L D L G FC T PP+ + G R+ F SD + GF Y
Sbjct: 646 DYLEIRDGPLYQDPLL--GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 1842 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 1901
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 1902 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 74.9 bits (176), Expect = 8e-13
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L GTI SP P +YP NC W I+ P H I L F F LE + C
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE----FHYNCT 986
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + V+ D G +CG ++PP +TS G+ L + F +D + GF Y
Sbjct: 987 NDYLEVYD---TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 2205 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 2262
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 2263 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 2317
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 2318 SDNSPTHVGFKAKYSI 2333
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFY-----EAVCGGDIEVDSN 59
P+LG+ C + P +++TG + + ++ +GF Y + CGG+ D
Sbjct: 659 PLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISD-QGFHITYLTSPSDLRCGGNY-TDPE 716
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L P + + C++ + PQ Q+ + F E++ S + ++VRDG++
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET--- 773
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+G CG+ I+S +N + + F+ D++V+KA F A +
Sbjct: 774 -LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Query: 2 PDAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDS 58
P++P++G+ CG+ ++S ++L V + L+ GF A + CGG D
Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATWNTQTLGCGGIFHSD- 2812
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHD-TCSYDKVKVRDG-D 115
NG + SP++P ++ N C W + + + F ++F + + D C VKV G +
Sbjct: 2813 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
+D L+ CG+ P + + SN +F+S + GFSA+F+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASFV 2917
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
G ++ T I SPN C W + P ++K+ +L Q+C +++
Sbjct: 3279 GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTS-QDCTQNYL 3337
Query: 426 TIYDGASADVKTLGIFCG---SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ D + FCG S +P + +S + ++FKS G V R ++
Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVP-VFYSSMSTAMVIFKS-GVVNRNSRMSFTYQIADC 3395
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ +L S + DN Y++ DC + AP+NH + L F + +E CR D++
Sbjct: 3396 NRDYHKAFGNLRSPG-WPDN-YDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFL 3453
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+V +CG +P + S + L +RF++D +G+
Sbjct: 3454 EVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 68.9 bits (161), Expect = 5e-11
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L G G I SP FP +YP + C W I P I LNFT F++ + CE
Sbjct: 816 ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSS----AHCE 870
Query: 265 YDSVTVHSK--LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D V + S LG+ ++ +CGT +P +TS + L V F S GF A +
Sbjct: 871 TDYVEIGSSSILGSPENKK---YCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Query: 323 DVDEC----AENNGGCQHECHNTLGGYECACHSGFTLHPN 358
+ C E+ G Q H + + C + PN
Sbjct: 928 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPN 967
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 1446
Query: 266 DSVTVHSKLGADV-LRRHGAFC---GTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 1447 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 1504
Query: 322 IDVDEC 327
C
Sbjct: 1505 AVTGGC 1510
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 2047 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 2104
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 2105 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDICSP 2164
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 2165 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 2031
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 2032 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSN 59
++P+LG+ CG+ + S + L + ++ + RG+ + + CGG + D
Sbjct: 3462 NSPLLGKYCGTLLPNPVFSQNNELYLRFKSD-SVTSDRGYEIIWTSSPSGCGGTLYGD-R 3519
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YP Y N C W L P V + F+ +++ C + + + DG + S
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASS 3579
Query: 120 PLIGMFCG--HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P G +CG I P + S SN++ + F +D + + F T+
Sbjct: 3580 PSSGPYCGGDTSIAPFVAS-SNQVFIKFHADYARRPSAFRLTW 3621
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEP----QDSC-- 1563
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 1564 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 2507
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 2508 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 2568 AVCGGSLPNTPEGNFTSPGYD 2588
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG GP+G I SP++P+ Y NC + I A P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 266 DSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D VH G V+ CG +P P+T G VL + F S+ + GF Y I
Sbjct: 2980 DG--VHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRI 3034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 190 DIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFT 249
D GYE+ + CGG LYG G+ TSP +P YP C W +VAP +T+NF
Sbjct: 3497 DRGYEIIWTSSP--SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFY 3554
Query: 250 HFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCG--TALPPPVTSDGSVLRVQFTS 307
++ +C + +T++ A G +CG T++ P V S V ++F +
Sbjct: 3555 FISIDD----PGDCVQNYLTLYDGPNAS-SPSSGPYCGGDTSIAPFVASSNQVF-IKFHA 3608
Query: 308 DGSVHRSGF 316
D + S F
Sbjct: 3609 DYARRPSAF 3617
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 2336 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 2391
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 2392 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2448
Query: 324 VDEC 327
++EC
Sbjct: 2449 MEEC 2452
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC + G+ SP YP YP C W G + + F ++ +C +++
Sbjct: 3510 GCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYL 3569
Query: 426 TIYDGASADVKTLGIFCGSKLPHL-VMASQNQMYMVFKSDGSVQRKGFLAT 475
T+YDG +A + G +CG +AS NQ+++ F +D + + F T
Sbjct: 3570 TLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLT 3620
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+ VCG + NG + Y + C W + + + F F +E+ D C +
Sbjct: 471 QQVCGESLS-GINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ ++V DGDS + +G FCG +P ++ S+ N L S+ GF+ + + E
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589
Query: 167 CASI 170
C I
Sbjct: 590 CGGI 593
Score = 57.6 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D +L CG+ GP++ + + T V+Q + P +GF A + + CG + S G+
Sbjct: 2875 DKALLATGCGNVAPGPVITPSNT-FTAVFQS--QEAPAQGFSASFVSRCGSNFTGPS-GY 2930
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSM 117
+ SPNYP Y N C + + V L F SF +E +C D V + G S+
Sbjct: 2931 IISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSV 2990
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S CG ++P + + + +L+ F S+ + GF ++
Sbjct: 2991 MSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 3032
Score = 56.0 bits (129), Expect = 4e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CG LS + +S+ R D Y +C W I+ +++TF F LE NC +
Sbjct: 474 CGESLSG---INGSFSY-RSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
+++QV+ FCG +P E++S+ AL ++ +GF+ ++ +P
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 588
Score = 55.2 bits (127), Expect = 7e-07
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD-S 58
+A + G CGS S+G+ LTV + L L+ GF A Y + CGG +
Sbjct: 3229 NANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE-REGFNATYTIMDMPCGGTYNATWT 3287
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
++ SPN D P +C W + P QV + + ++ + D C+ + ++++D
Sbjct: 3288 PQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGH 3346
Query: 119 SPLIGMFCGHKIP--PDIRSTSNKLLVIFESDSTVQKAGFSATF 160
FCG P S+ + +VIF+S + + S T+
Sbjct: 3347 GNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTY 3390
Score = 54.4 bits (125), Expect = 1e-06
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ ++ + AC GT TSP+FP YP C++ I I ++FT+F
Sbjct: 1034 GFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
Query: 252 DLE---GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
LE GN+ Y G + G F G+ LPP + S + L ++F SD
Sbjct: 1094 SLEEAIGNY-------YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSD 1146
Query: 309 GSVHRSGFAAVYYIDVDECAEN 330
RSGF+A + C N
Sbjct: 1147 QIDTRSGFSAYWDGSSTGCGGN 1168
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP +P+ Y K+C + AP H I+L F +E + EC D + V +
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENS----VECRNDFLEVRNGS 3459
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
++ G +CGT LP PV S + L ++F SD G+ ++ C
Sbjct: 3460 NSNSPLL-GKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGC 3511
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 1856 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 1911
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT +S G+ L F SD S+ GF ++
Sbjct: 1912 IYD--GPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 7/129 (5%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ + DG CGG L +GT SP++P Y C W + + L F F
Sbjct: 1153 GFSAYWDGSS--TGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDF 1210
Query: 252 DLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
LE + C D + V+ ++ CG PP + S G + ++ +D
Sbjct: 1211 HLE----HHPNCTLDYLAVYDGPSSN-SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ 1265
Query: 312 HRSGFAAVY 320
GF A Y
Sbjct: 1266 QGRGFKAEY 1274
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + S +P Y ++C W I A + + F FDLE +H+ C D + ++
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLE-HHI---NCSTDYLELY--- 1341
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 1342 --DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 1388
Score = 48.8 bits (111), Expect = 6e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 205 ACGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+CGG +G ITSP++ YP +CL+ I I L F+ FD+ + C
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV----VPSTSC 3091
Query: 264 EYDSVTVHSKLG-ADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
+D + ++ +D L G FCG+ PP V S + + + F +D
Sbjct: 3092 SHDYLAIYDGANTSDPLL--GKFCGSKRPPNVKSSNNSMLLVFKTD 3135
Score = 48.4 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE---NACGGALYGPNGTIT 218
+ +EC S +CV+ + + C C + G C+ CG +L G NG+ +
Sbjct: 431 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWT----GALCQVPQQVCGESLSGINGSFS 486
Query: 219 SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADV 278
S Y NC W I + + FT F LE C ++ + V+ +
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLES----MDNCPHEFLQVYDGDSSSA 542
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
+ G FCG++LP + S + L S+ + GF + EC
Sbjct: 543 FQL-GRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC 590
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + NGTI SP +P+ +P C W + + ++F + L + Q + +
Sbjct: 2805 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
V ++ L G CG P PV + + F S GF+A + V
Sbjct: 2865 VKVWAGTEEVDKALLATG--CGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF---VS 2918
Query: 326 ECAENNGG 333
C N G
Sbjct: 2919 RCGSNFTG 2926
Score = 46.4 bits (105), Expect = 3e-04
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P G + P + + C++ + P +I +NFTH +L +C+
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVEL--------QCQS 759
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
DS + ++ D G CG + S + + ++F D SV ++ F AVY +
Sbjct: 760 DSSQNYIEV-RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815
Score = 33.5 bits (73), Expect = 2.4
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 5/36 (13%)
Query: 323 DVDECAENNGGCQ----HECHNTLGGYEC-ACHSGF 353
D++EC NNGGC EC NT G C AC G+
Sbjct: 305 DINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 340
>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin B12
receptor protein.
Length = 3494
Score = 139 bits (337), Expect = 2e-32
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 1379 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC---- 1434
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 1435 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 1494
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 1495 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 1550
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 1551 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 1598
Score = 139 bits (336), Expect = 3e-32
Identities = 111/400 (27%), Positives = 174/400 (43%), Gaps = 54/400 (13%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 1962 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2021
Query: 264 EY----DSVTVHS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAA 318
+Y + ++S LG +G FCG+ + + + + VQF SD S GF
Sbjct: 2022 DYLVLRNGPDIYSPPLGPP--GGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKI 2079
Query: 319 VYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTI 378
Y C GG + H+ A +G+ PN PH
Sbjct: 2080 KYEAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH--- 2110
Query: 379 FSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKT 437
NYP DC+W + P RI+L F + F++E C +++ + DG +D
Sbjct: 2111 ---NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPI 2163
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSH 496
L FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 2164 LSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGH 2223
Query: 497 AR--YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXX 554
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 2224 PTLPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNI 2277
Query: 555 XXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 2278 LGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 2317
Score = 135 bits (327), Expect = 4e-31
Identities = 80/231 (34%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G I SP Y A YP C++ + + I+L F+ F++ P C++D++ IYDGA+
Sbjct: 2917 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTS 2976
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF-LATHST-----ACGGYLSATE 488
LG FCGSK P V +S N M +VFK+D KG+ ++ T CGGYL+ +
Sbjct: 2977 DPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSN 3036
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA---NCRYDYVQVF 545
S + Y+ +C W I AP N + LTF TF LE + C YDYV+++
Sbjct: 3037 NT--FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLY 3094
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
TFCG +P +S+ L V+F +D +L +GF+A+Y ++
Sbjct: 3095 DGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3145
Score = 132 bits (318), Expect = 5e-30
Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
SGF+ + D GC ++T GT SPNYP Y +C W ++ G +L F
Sbjct: 1023 SGFSAY---WDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFK 1079
Query: 411 VFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRK 470
F LE H C D++ +YDG S++ L CG + P L+ +S + M++ ++D Q +
Sbjct: 1080 DFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGR 1139
Query: 471 GFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFE 530
GF A + C + + L S N Y C+W I A + V TFL F+
Sbjct: 1140 GFKAEYRQTCENVVIVNQTYGILESIGY--PNPYSENQHCNWTIRATTGNTVNYTFLAFD 1197
Query: 531 LEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
LE NC DY++++ +CG+ +PP +TS L V TD
Sbjct: 1198 LEHHINCSTDYLELY----DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTD 1244
Score = 129 bits (311), Expect = 3e-29
Identities = 65/171 (38%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
Query: 3 DAPVLGRLCGSGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D P++ RLCG K + + S++ + + R++ H GF A Y G I++ +G
Sbjct: 2512 DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVE-HIGFHAKYSFTDCGGIQIGDSGV 2570
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
+ SPNYP+ Y C W L PQ + + L F F++E H TC++D V VR+G S +SP+
Sbjct: 2571 ITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPI 2630
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH 172
IG +CG+ P I+S SN+L+V F SD ++Q GF AT+ + C I H
Sbjct: 2631 IGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFH 2681
Score = 124 bits (298), Expect = 1e-27
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 8/232 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY-DHV 425
C D T GT SPN+P YP +C+++ + G I + F F LE Y D +
Sbjct: 919 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFL 978
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLAT---HSTACGG 482
I DG LGIF GS LP +++ N++++ FKSD R GF A ST CGG
Sbjct: 979 EIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGG 1038
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L+ + + Y Y S ++C W +++ +L F F LE NC DY+
Sbjct: 1039 NLTTSSGT---FISPNYPMPYYHS-SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1094
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
V+ CG + PP I S+ +++ ++ RTD+ +GF A Y+
Sbjct: 1095 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1146
Score = 121 bits (292), Expect = 7e-27
Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T G I SP +P YP + C W I L F VFE+ C D+V
Sbjct: 688 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 746
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGGY 483
I + +CG+ +P + + N +Y+ F S + GF+A S ACG
Sbjct: 747 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 806
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L TE + S N Y +C W+I NH + L F TF LE NC DY++
Sbjct: 807 L--TESTGTIQSPGH--PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 862
Query: 544 VFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
V+ +CG +PP + S+ +L++ F TD L ++GF +Y+ +
Sbjct: 863 VYDTDSETSLGR--YCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 913
Score = 117 bits (282), Expect = 1e-25
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 1494 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1553
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 1554 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 1613
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 1614 YMAEGI---FNSPGYPD-IYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVEI 1669
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 1670 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 1721
Score = 113 bits (272), Expect = 2e-24
Identities = 68/225 (30%), Positives = 111/225 (49%), Gaps = 13/225 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G I SPNYP AY + C W GH I L F+ F++EPH CA+D VT+ +G S +
Sbjct: 2569 GVITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPES 2628
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGG-YLSATEEVK 491
+G +CG+ P + + NQ+ + F SD S+Q GF AT +T CGG + S ++
Sbjct: 2629 PIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIR 2688
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFEL--EREANCRYDYVQVFX-XX 548
+ + +N SR C W ++ ++++F L + C+ +V+V+
Sbjct: 2689 SPHWPQNFPEN---SR--CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2743
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
T CG P +++ S F++ ++ +GFSAS+
Sbjct: 2744 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPA-QGFSASF 2787
Score = 111 bits (268), Expect = 6e-24
Identities = 67/236 (28%), Positives = 109/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 1261 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 1320
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 1321 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 1380
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I R H V L F F+LE + +C
Sbjct: 1381 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC-- 1434
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 1435 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1488
Score = 111 bits (267), Expect = 7e-24
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
K ++ C +T GTI SP +P YP +C W P H I L+F F LE H
Sbjct: 795 KFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 854
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS- 477
C D++ +YD S +LG +CG +P + +S N + +VF +D + +GFL +
Sbjct: 855 NCTNDYLEVYDTDSE--TSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEA 912
Query: 478 -TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
+A L + ++ + +N Y + +C + I + + F F LE
Sbjct: 913 ISAATACLQDYTDDLGTFTSPNFPNN-YPNNWECIYRITVRTGQLIAVHFTNFSLEEAIG 971
Query: 537 CRY-DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSA 591
Y D++++ F G +PP I+S S L ++F++D GFSA
Sbjct: 972 NYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1027
Score = 104 bits (249), Expect = 1e-21
Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%)
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDG 430
V +G + S YP Y + C W T G+ + F F+LE H C+ D++ +YDG
Sbjct: 1155 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1214
Query: 431 ASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYLSATE 488
+ +G +CG LP + +++ ++ +DG +R KGF + CGG LS
Sbjct: 1215 P----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGAT 1270
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXX 548
+S + N Y +C W I ++LT F++E + C +D ++++
Sbjct: 1271 GS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGP 1326
Query: 549 XXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 1327 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1377
Score = 103 bits (248), Expect = 1e-21
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 12/236 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 2323 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2382
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 2383 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2442
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTFELEREANCRY 539
G L T E + S G Y +C+W + P N + + F F LE +C++
Sbjct: 2443 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQF 2501
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMP--PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D ++ F CG P P ++ S+ + + F T++ + GF A Y
Sbjct: 2502 DVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKY 2555
Score = 103 bits (246), Expect = 3e-21
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 9/227 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P G +F P + + CV+ G +I++ F EL+ + + +++
Sbjct: 579 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 638
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG + LG CG+ + + N +++ FK D SV++ F A + ACG L+
Sbjct: 639 VRDGETL----LGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 694
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
++ + + N Y C W I P++ + L F FE+ A+C DYV++
Sbjct: 695 EGVIR-----SPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGS 749
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG +P I S L V F S GF A +
Sbjct: 750 SSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF 796
Score = 101 bits (241), Expect = 1e-20
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 15/277 (5%)
Query: 323 DVDECAEN---NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIF 379
+++EC N NGG C + + + C C +T + C ++ +G+
Sbjct: 303 NINECLSNPCLNGGT---CVDGVDSFSCECTRLWT--GALCQVPQQVCGESLSGINGSFS 357
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLG 439
+ Y +C W T G +++ F F LE C ++ + +YDG S+ LG
Sbjct: 358 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLG 417
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA---THSTACGGYLSATEEVKHLYSH 496
FCGS LPH +++S N +Y S+ +GF T CGG L T + S
Sbjct: 418 RFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGIL--TGPYGSIKSP 475
Query: 497 ARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
G+ Y DC W + + V TF T LE +C DY+++
Sbjct: 476 GYPGN--YPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLG 533
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FC P + +T + F +D + +GF +Y
Sbjct: 534 KFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 570
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 1448 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 1505
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 1506 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 1565
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 1566 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 1609
Score = 100 bits (239), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 1609 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVE 1668
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 1669 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 1724
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 1725 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1784
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 1785 DGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1827
Score = 99.1 bits (236), Expect = 4e-20
Identities = 60/226 (26%), Positives = 107/226 (47%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 1862 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 1920
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 1921 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 1977
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ ++
Sbjct: 1978 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSPP 2036
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 2037 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 2082
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 1972 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2031
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 2032 IYSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 2091
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 2092 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 2151
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 2152 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 2206
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 10/220 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D G + SP +P Y KDC + H I L F+ +E EC D +
Sbjct: 3266 CNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLE 3325
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF--LATHS-TACGGY 483
+ +G++++ LG +CG+ LP+ V + N++Y+ FKSD +G+ + T S + CGG
Sbjct: 3326 VRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGT 3385
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L + ++ Y Y + C+W + AP V + F ++ +C +Y+
Sbjct: 3386 LYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3441
Query: 544 VFXXXXXXXXXXXTFCG--IKMPPEIVSTSEALLVRFRTD 581
++ +CG + P V++S + ++F D
Sbjct: 3442 LYDGPNASSPSSGPYCGGDTSIAP-FVASSNQVFIKFHAD 3480
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 1218 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 1276
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 1277 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 1336
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 1337 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 1384
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 1849 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 1907
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 1908 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 1967
Query: 169 SIDHG 173
D G
Sbjct: 1968 HADRG 1972
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/157 (36%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDI----EVDSNGHL 62
LGR CG P + S+G+ L +V+ L + GF YEA+ D G
Sbjct: 872 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLA-YEGFLINYEAISAATACLQDYTDDLGTF 930
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY-DKVKVRDGDSMDSPL 121
SPN+P++Y N CI++++V +A+ F +F +E Y D +++RDG SPL
Sbjct: 931 TSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPL 990
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSA 158
+G+F G +PP I S SNKL + F+SD ++GFSA
Sbjct: 991 LGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1027
Score = 95.5 bits (227), Expect = 5e-19
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Query: 9 RLCGSGKG--PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPN 66
+ CG P+ S+ S V+++ G+ + R + A C D + G+L SP
Sbjct: 3223 QFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYH-KAFGNLRSPG 3281
Query: 67 YPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFC 126
+PD+Y +K C L+ PQ++ ++L FHS +EN C D ++VR+G + +SPL+G +C
Sbjct: 3282 WPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYC 3341
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG 173
G +P + S +N+L + F+SDS G+ + C +G
Sbjct: 3342 GTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGTLYG 3388
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 1560 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 1617
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 1618 GIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 1676
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 1677 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 1722
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 2044 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 2102
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 2103 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 2162
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 2163 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 2202
Score = 92.3 bits (219), Expect = 5e-18
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 13/235 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ----ECAY 422
C + T P G I SPNYP Y +C + P + L F F LE C
Sbjct: 2791 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2850
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-TACG 481
D V I G S CG ++P + + + F S+ + GF ++ +CG
Sbjct: 2851 DGVHIIRGYSVMSTPFATVCGDEMP-APLTIAGPVLLNFYSNEQITDFGFKFSYRIISCG 2909
Query: 482 GYLSATEEV--KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
G + + + YS+A Y ++ + C + I + ++L F F++ +C +
Sbjct: 2910 GVFNFSSGIITSPAYSYADYPNDMH-----CLYTITVSDDKVIELKFSDFDVVPSTSCSH 2964
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+ ++ FCG K PP + S++ ++L+ F+TD KG+ S++
Sbjct: 2965 DYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR 3019
Score = 91.9 bits (218), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
LGR CGS + S+ + L +Y LR RGF +E CGG I G +
Sbjct: 416 LGRFCGSSLPHELLSSDNALYFHLYSEHLR--NGRGFTVRWETQQPECGG-ILTGPYGSI 472
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
+SP YP +Y P + C+W + D V F + +E+HD C+ D +++RDG PL+
Sbjct: 473 KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLL 532
Query: 123 GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
G FC P +++T + F SDS + GF T++
Sbjct: 533 GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 571
Score = 91.9 bits (218), Expect = 6e-18
Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 13/167 (7%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV------CGGDIEVDS 58
P+LG+ CGS + P ++S+ + + +V++ + +G++ + CGG + S
Sbjct: 2978 PLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTAKGWKMSFRQTLGPQQGCGGYL-TGS 3035
Query: 59 NGHLESPNYPDD--YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT---CSYDKVKVRD 113
N SP+ + Y N C+W + P + + L F++F +E T C YD VK+ D
Sbjct: 3036 NNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYD 3095
Query: 114 GDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
GDS ++ L G FCG +P S+ N L V F SD T+++ GF+AT+
Sbjct: 3096 GDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3142
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 352 GFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV 411
GFT+ + + ++ C +T P+G+I SP YP YP +DCVW T+P + F
Sbjct: 449 GFTV---RWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 505
Query: 412 FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKG 471
LE H +C D++ I DG LG FC + + + + F SD + +G
Sbjct: 506 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 565
Query: 472 FLATHSTA-----CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
F T+ T+ CGG + T+ L+ G + C + ++ P+ +++ F
Sbjct: 566 FHITYLTSPSDLRCGG--NYTDPEGELFLPELSGP--FTHTRQCVYMMKQPQGEQIQINF 621
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
EL+ +++ +Y++V CG I S + ++ +RF+ D S+
Sbjct: 622 THVELQCQSDSSQNYIEV----RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEK 677
Query: 587 KGFSASYQM 595
F A YQ+
Sbjct: 678 ASFRAVYQV 686
Score = 89.0 bits (211), Expect = 4e-17
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNG 60
+P+LG GS P + S ++L + ++ ++ GF A+++ CGG++ S+G
Sbjct: 988 SPLLGIFYGSNLPPTIISHSNKLWLKFKSD-QIDTRSGFSAYWDGSSTGCGGNLTT-SSG 1045
Query: 61 HLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
SPNYP Y + C W L L F F +E+H C+ D + V DG S +S
Sbjct: 1046 TFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSH 1105
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+ CG + PP IRS+ + + + +D Q GF A +
Sbjct: 1106 LLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1145
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 2160 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 2217
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 2218 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 2276
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 2277 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 2323
Score = 87.8 bits (208), Expect = 1e-16
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVE 99
GF+ Y + G + S+G + SP Y PN + C++ ++V D + L+F F+V
Sbjct: 2898 GFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV 2957
Query: 100 NHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSAT 159
+CS+D + + DG + PL+G FCG K PP+++S++N +L++F++DS G+ +
Sbjct: 2958 PSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3017
Query: 160 F 160
F
Sbjct: 3018 F 3018
Score = 86.2 bits (204), Expect = 3e-16
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESP 65
+LG++CG+G ++S + + + ++ ++ FRA Y+ CG E+ G + SP
Sbjct: 645 LLGKVCGNGTISHIKSITNSVWIRFKIDASVEK-ASFRAVYQVACGD--ELTGEGVIRSP 701
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y + C W + PQ + L F FE+ + C D V++ + SP +
Sbjct: 702 FFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY 761
Query: 126 CGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
CG IP I S N L V F S+ + GF A F E C I
Sbjct: 762 CGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 806
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 1490 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 1545
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 1546 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1604
Query: 323 DVDEC 327
V C
Sbjct: 1605 SVSAC 1609
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA--VCGGDIEVDSNGH 61
+P + CG+ + S + L V + + H GF A + A + G+I +S G
Sbjct: 755 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENH-GFMAKFSAEDLACGEILTESTGT 813
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
++SP +P+ Y C W + V ++ + L F +F +E H C+ D ++V D DS S
Sbjct: 814 IQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-- 871
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG IPP + S+ N L+++F +DS + GF
Sbjct: 872 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 906
Score = 85.0 bits (201), Expect = 7e-16
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 9/137 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG G +G ITSP++P Y L +C W + AP H ITL F+ FD+E + C +
Sbjct: 2560 CGGIQIGDSGVITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPH----TTCAW 2615
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
DSVTV + G+ G +CG + P + S + L V F SD S+ GF A +
Sbjct: 2616 DSVTVRNG-GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTL 2674
Query: 326 ECAENNGGCQHECHNTL 342
C GG H + T+
Sbjct: 2675 GC----GGIFHSDNGTI 2687
Score = 82.6 bits (195), Expect = 4e-15
Identities = 55/164 (33%), Positives = 85/164 (51%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 1330 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 1388
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V + ++V L F F++E D+C + DG S
Sbjct: 1389 S-GEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC----IMAYDGLSS 1443
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 1444 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1487
Score = 82.2 bits (194), Expect = 5e-15
Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-GHLES 64
+L +LCG K P++RS+G + + + + RGF+A Y C + V+ G LES
Sbjct: 1106 LLTQLCGDEKPPLIRSSGDSMFIKLRTD-EGQQGRGFKAEYRQTCENVVIVNQTYGILES 1164
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGM 124
YP+ Y N+ C W + V F +F++E+H CS D +++ DG +G
Sbjct: 1165 IGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1220
Query: 125 FCGHKIPPDIRSTSNKLLVIFESD 148
+CG +PP +TS+KL V+ +D
Sbjct: 1221 YCGVDLPPPGSTTSSKLQVLLLTD 1244
Score = 81.8 bits (193), Expect = 7e-15
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 203 ENACGGALYGPNGTITSPSFPE--LYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+ CGG L G N T SP +Y NC+W I+AP I L F F LE +
Sbjct: 3025 QQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST-R 3083
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
Q C YD V ++ ++ G FCG+ +P P S G+ L VQF SD ++ R GF A Y
Sbjct: 3084 QRCLYDYVKLYDG-DSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3142
Query: 321 YI 322
I
Sbjct: 3143 TI 3144
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 2277 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 2334
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 2335 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 2394
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 2395 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2438
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/118 (36%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W I++ P +R+ L+F F LE + Q+C
Sbjct: 1607 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDS----QDC 1662
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 1663 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1718
Score = 79.8 bits (188), Expect = 3e-14
Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 16/184 (8%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 2390 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 2447
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQ--DYQVALRFHSFEVENHDTCSYDKVKVR 112
G+ SP Y +Y N C W LS P + +++ F F +E+H C +D ++ R
Sbjct: 2448 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFR 2507
Query: 113 DGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
GD+ D PL+ CG P + +++ + F ++ V+ GF A + F +C I
Sbjct: 2508 VGDA-DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY--SFTDCGGIQ 2564
Query: 172 HGCS 175
G S
Sbjct: 2565 IGDS 2568
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/238 (25%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP--HQECAYD 423
GC +GTI SP++P +P C W T +++ F+ L P +C
Sbjct: 2675 GCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNS 2734
Query: 424 HVTIYDGA-SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
V ++ G D L CG+ P V+ N VF+S +GF A+ + CG
Sbjct: 2735 FVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCGS 2793
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA----NCR 538
+ Y + Y++ +C + IEA V LTF++F LE + +C
Sbjct: 2794 NFTGPSG----YIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2849
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
D V + T CG +MP + LL F +++ + GF SY+++
Sbjct: 2850 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLL-NFYSNEQITDFGFKFSYRII 2906
Score = 75.8 bits (178), Expect = 4e-13
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G+I SP +P YPP ++C+W +V P +T F LE + +C
Sbjct: 461 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLE----HHDDCNK 516
Query: 266 DSVTVH-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + L D L G FC T PP+ + G R+ F SD + GF Y
Sbjct: 517 DYLEIRDGPLYQDPLL--GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 570
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 1713 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 1772
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 1773 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1827
Score = 74.9 bits (176), Expect = 8e-13
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L GTI SP P +YP NC W I+ P H I L F F LE + C
Sbjct: 802 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE----FHYNCT 857
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + V+ D G +CG ++PP +TS G+ L + F +D + GF Y
Sbjct: 858 NDYLEVYD---TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 910
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 2076 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 2133
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 2134 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 2188
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 2189 SDNSPTHVGFKAKYSI 2204
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFY-----EAVCGGDIEVDSN 59
P+LG+ C + P +++TG + + ++ +GF Y + CGG+ D
Sbjct: 530 PLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISD-QGFHITYLTSPSDLRCGGNY-TDPE 587
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L P + + C++ + PQ Q+ + F E++ S + ++VRDG++
Sbjct: 588 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET--- 644
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+G CG+ I+S +N + + F+ D++V+KA F A +
Sbjct: 645 -LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 684
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Query: 2 PDAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDS 58
P++P++G+ CG+ ++S ++L V + L+ GF A + CGG D
Sbjct: 2626 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATWNTQTLGCGGIFHSD- 2683
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHD-TCSYDKVKVRDG-D 115
NG + SP++P ++ N C W + + + F ++F + + D C VKV G +
Sbjct: 2684 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2743
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
+D L+ CG+ P + + SN +F+S + GFSA+F+
Sbjct: 2744 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASFV 2788
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
G ++ T I SPN C W + P ++K+ +L Q+C +++
Sbjct: 3150 GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTS-QDCTQNYL 3208
Query: 426 TIYDGASADVKTLGIFCG---SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ D + FCG S +P + +S + ++FKS G V R ++
Sbjct: 3209 QLQDSPQGHGNSRFQFCGRNASAVP-VFYSSMSTAMVIFKS-GVVNRNSRMSFTYQIADC 3266
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ +L S + DN Y++ DC + AP+NH + L F + +E CR D++
Sbjct: 3267 NRDYHKAFGNLRSPG-WPDN-YDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFL 3324
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+V +CG +P + S + L +RF++D +G+
Sbjct: 3325 EVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3371
Score = 68.9 bits (161), Expect = 5e-11
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L G G I SP FP +YP + C W I P I LNFT F++ + CE
Sbjct: 687 ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSS----AHCE 741
Query: 265 YDSVTVHSK--LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D V + S LG+ ++ +CGT +P +TS + L V F S GF A +
Sbjct: 742 TDYVEIGSSSILGSPENKK---YCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 798
Query: 323 DVDEC----AENNGGCQHECHNTLGGYECACHSGFTLHPN 358
+ C E+ G Q H + + C + PN
Sbjct: 799 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPN 838
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 1262 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 1317
Query: 266 DSVTVHSKLGADVLR-RHGAFCGTALPP---PVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 1318 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 1375
Query: 322 IDVDEC 327
C
Sbjct: 1376 AVTGGC 1381
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 1918 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 1975
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 1976 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSP 2035
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 2036 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2081
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 1848 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 1902
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 1903 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 1960
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSN 59
++P+LG+ CG+ + S + L + ++ + RG+ + + CGG + D
Sbjct: 3333 NSPLLGKYCGTLLPNPVFSQNNELYLRFKSD-SVTSDRGYEIIWTSSPSGCGGTLYGD-R 3390
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YP Y N C W L P V + F+ +++ C + + + DG + S
Sbjct: 3391 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASS 3450
Query: 120 PLIGMFCG--HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P G +CG I P + S SN++ + F +D + + F T+
Sbjct: 3451 PSSGPYCGGDTSIAPFVAS-SNQVFIKFHADYARRPSAFRLTW 3492
Score = 62.1 bits (144), Expect = 6e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 1381 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEP----QDSC-- 1434
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 1435 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1487
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 2323 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 2378
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 2379 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2438
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 2439 AVCGGSLPNTPEGNFTSPGYD 2459
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG GP+G I SP++P+ Y NC + I A P + L F F LE C
Sbjct: 2791 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2850
Query: 266 DSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D VH G V+ CG +P P+T G VL + F S+ + GF Y I
Sbjct: 2851 DG--VHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRI 2905
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 190 DIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFT 249
D GYE+ + CGG LYG G+ TSP +P YP C W +VAP +T+NF
Sbjct: 3368 DRGYEIIWTSSP--SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFY 3425
Query: 250 HFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCG--TALPPPVTSDGSVLRVQFTS 307
++ +C + +T++ A G +CG T++ P V S V ++F +
Sbjct: 3426 FISIDD----PGDCVQNYLTLYDGPNAS-SPSSGPYCGGDTSIAPFVASSNQVF-IKFHA 3479
Query: 308 DGSVHRSGF 316
D + S F
Sbjct: 3480 DYARRPSAF 3488
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 2207 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 2262
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 2263 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2319
Query: 324 VDEC 327
++EC
Sbjct: 2320 MEEC 2323
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC + G+ SP YP YP C W G + + F ++ +C +++
Sbjct: 3381 GCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYL 3440
Query: 426 TIYDGASADVKTLGIFCGSKLPHL-VMASQNQMYMVFKSDGSVQRKGFLAT 475
T+YDG +A + G +CG +AS NQ+++ F +D + + F T
Sbjct: 3441 TLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLT 3491
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+ VCG + NG + Y + C W + + + F F +E+ D C +
Sbjct: 342 QQVCGESLS-GINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 400
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ ++V DGDS + +G FCG +P ++ S+ N L S+ GF+ + + E
Sbjct: 401 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 460
Query: 167 CASI 170
C I
Sbjct: 461 CGGI 464
Score = 57.6 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D +L CG+ GP++ + + T V+Q + P +GF A + + CG + S G+
Sbjct: 2746 DKALLATGCGNVAPGPVITPSNT-FTAVFQS--QEAPAQGFSASFVSRCGSNFTGPS-GY 2801
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSM 117
+ SPNYP Y N C + + V L F SF +E +C D V + G S+
Sbjct: 2802 IISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSV 2861
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S CG ++P + + + +L+ F S+ + GF ++
Sbjct: 2862 MSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 2903
Score = 56.0 bits (129), Expect = 4e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CG LS + +S+ R D Y +C W I+ +++TF F LE NC +
Sbjct: 345 CGESLSG---INGSFSY-RSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 400
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
+++QV+ FCG +P E++S+ AL ++ +GF+ ++ +P
Sbjct: 401 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 459
Score = 55.2 bits (127), Expect = 7e-07
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD-S 58
+A + G CGS S+G+ LTV + L L+ GF A Y + CGG +
Sbjct: 3100 NANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE-REGFNATYTIMDMPCGGTYNATWT 3158
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
++ SPN D P +C W + P QV + + ++ + D C+ + ++++D
Sbjct: 3159 PQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGH 3217
Query: 119 SPLIGMFCGHKIP--PDIRSTSNKLLVIFESDSTVQKAGFSATF 160
FCG P S+ + +VIF+S + + S T+
Sbjct: 3218 GNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTY 3261
Score = 54.4 bits (125), Expect = 1e-06
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ ++ + AC GT TSP+FP YP C++ I I ++FT+F
Sbjct: 905 GFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 964
Query: 252 DLE---GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
LE GN+ Y G + G F G+ LPP + S + L ++F SD
Sbjct: 965 SLEEAIGNY-------YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSD 1017
Query: 309 GSVHRSGFAAVYYIDVDECAEN 330
RSGF+A + C N
Sbjct: 1018 QIDTRSGFSAYWDGSSTGCGGN 1039
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP +P+ Y K+C + AP H I+L F +E + EC D + V +
Sbjct: 3275 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENS----VECRNDFLEVRNGS 3330
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
++ G +CGT LP PV S + L ++F SD G+ ++ C
Sbjct: 3331 NSNSPLL-GKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGC 3382
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 1727 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 1782
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT +S G+ L F SD S+ GF ++
Sbjct: 1783 IYD--GPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1832
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 7/129 (5%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ + DG CGG L +GT SP++P Y C W + + L F F
Sbjct: 1024 GFSAYWDGSS--TGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDF 1081
Query: 252 DLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
LE + C D + V+ ++ CG PP + S G + ++ +D
Sbjct: 1082 HLE----HHPNCTLDYLAVYDGPSSN-SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ 1136
Query: 312 HRSGFAAVY 320
GF A Y
Sbjct: 1137 QGRGFKAEY 1145
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + S +P Y ++C W I A + + F FDLE +H+ C D + ++
Sbjct: 1160 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLE-HHI---NCSTDYLELY--- 1212
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 1213 --DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 1259
Score = 48.8 bits (111), Expect = 6e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 205 ACGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+CGG +G ITSP++ YP +CL+ I I L F+ FD+ + C
Sbjct: 2907 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV----VPSTSC 2962
Query: 264 EYDSVTVHSKLG-ADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
+D + ++ +D L G FCG+ PP V S + + + F +D
Sbjct: 2963 SHDYLAIYDGANTSDPLL--GKFCGSKRPPNVKSSNNSMLLVFKTD 3006
Score = 48.4 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE---NACGGALYGPNGTIT 218
+ +EC S +CV+ + + C C + G C+ CG +L G NG+ +
Sbjct: 302 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWT----GALCQVPQQVCGESLSGINGSFS 357
Query: 219 SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADV 278
S Y NC W I + + FT F LE C ++ + V+ +
Sbjct: 358 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLES----MDNCPHEFLQVYDGDSSSA 413
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
+ G FCG++LP + S + L S+ + GF + EC
Sbjct: 414 FQL-GRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC 461
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + NGTI SP +P+ +P C W + + ++F + L + Q + +
Sbjct: 2676 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2735
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
V ++ L G CG P PV + + F S GF+A + V
Sbjct: 2736 VKVWAGTEEVDKALLATG--CGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF---VS 2789
Query: 326 ECAENNGG 333
C N G
Sbjct: 2790 RCGSNFTG 2797
Score = 46.4 bits (105), Expect = 3e-04
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P G + P + + C++ + P +I +NFTH +L +C+
Sbjct: 579 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVEL--------QCQS 630
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
DS + ++ D G CG + S + + ++F D SV ++ F AVY +
Sbjct: 631 DSSQNYIEV-RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 686
Score = 33.9 bits (74), Expect = 1.8
Identities = 53/218 (24%), Positives = 81/218 (37%), Gaps = 21/218 (9%)
Query: 150 TVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGK-KCENACG 207
TV K S+ + C ++ C G C+ D+ E++S C+N G
Sbjct: 1 TVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQN--G 58
Query: 208 GALYGPNGTITSPSFPELYPP-----LKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
G G+ + PE Y P +C VA H I + + G Y
Sbjct: 59 GTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMR-EQAGEPKYSCV 117
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C+ ++ + + R +F P P ++ Q + +G+ YI
Sbjct: 118 CDAGWMSSPNSPACTLDRDECSF----QPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 173
Query: 323 --DVDECAENNGGCQ----HECHNTLGGYEC-ACHSGF 353
D++EC NNGGC EC NT G C AC G+
Sbjct: 174 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 211
>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
receptor precursor protein.
Length = 3623
Score = 139 bits (337), Expect = 2e-32
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 1508 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC---- 1563
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 1564 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 1623
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 1624 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 1679
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 1680 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 1727
Score = 139 bits (336), Expect = 3e-32
Identities = 111/400 (27%), Positives = 174/400 (43%), Gaps = 54/400 (13%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 2091 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 2150
Query: 264 EY----DSVTVHS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAA 318
+Y + ++S LG +G FCG+ + + + + VQF SD S GF
Sbjct: 2151 DYLVLRNGPDIYSPPLGPP--GGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKI 2208
Query: 319 VYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTI 378
Y C GG + H+ A +G+ PN PH
Sbjct: 2209 KYEAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH--- 2239
Query: 379 FSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKT 437
NYP DC+W + P RI+L F + F++E C +++ + DG +D
Sbjct: 2240 ---NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPI 2292
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSH 496
L FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 2293 LSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGH 2352
Query: 497 AR--YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXX 554
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 2353 PTLPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNI 2406
Query: 555 XXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 2407 LGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 2446
Score = 135 bits (327), Expect = 4e-31
Identities = 80/231 (34%), Positives = 120/231 (51%), Gaps = 12/231 (5%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G I SP Y A YP C++ + + I+L F+ F++ P C++D++ IYDGA+
Sbjct: 3046 GIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGANTS 3105
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF-LATHST-----ACGGYLSATE 488
LG FCGSK P V +S N M +VFK+D KG+ ++ T CGGYL+ +
Sbjct: 3106 DPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQQGCGGYLTGSN 3165
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA---NCRYDYVQVF 545
S + Y+ +C W I AP N + LTF TF LE + C YDYV+++
Sbjct: 3166 NT--FASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLY 3223
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
TFCG +P +S+ L V+F +D +L +GF+A+Y ++
Sbjct: 3224 DGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATYTIM 3274
Score = 132 bits (318), Expect = 5e-30
Identities = 72/231 (31%), Positives = 108/231 (46%), Gaps = 9/231 (3%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
SGF+ + D GC ++T GT SPNYP Y +C W ++ G +L F
Sbjct: 1152 SGFSAY---WDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFK 1208
Query: 411 VFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRK 470
F LE H C D++ +YDG S++ L CG + P L+ +S + M++ ++D Q +
Sbjct: 1209 DFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGR 1268
Query: 471 GFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFE 530
GF A + C + + L S N Y C+W I A + V TFL F+
Sbjct: 1269 GFKAEYRQTCENVVIVNQTYGILESIGY--PNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326
Query: 531 LEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTD 581
LE NC DY++++ +CG+ +PP +TS L V TD
Sbjct: 1327 LEHHINCSTDYLELY----DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 129 bits (311), Expect = 3e-29
Identities = 65/171 (38%), Positives = 98/171 (57%), Gaps = 2/171 (1%)
Query: 3 DAPVLGRLCGSGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D P++ RLCG K + + S++ + + R++ H GF A Y G I++ +G
Sbjct: 2641 DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVE-HIGFHAKYSFTDCGGIQIGDSGV 2699
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
+ SPNYP+ Y C W L PQ + + L F F++E H TC++D V VR+G S +SP+
Sbjct: 2700 ITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPI 2759
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDH 172
IG +CG+ P I+S SN+L+V F SD ++Q GF AT+ + C I H
Sbjct: 2760 IGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFH 2810
Score = 124 bits (298), Expect = 1e-27
Identities = 74/232 (31%), Positives = 110/232 (47%), Gaps = 8/232 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAY-DHV 425
C D T GT SPN+P YP +C+++ + G I + F F LE Y D +
Sbjct: 1048 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFL 1107
Query: 426 TIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLAT---HSTACGG 482
I DG LGIF GS LP +++ N++++ FKSD R GF A ST CGG
Sbjct: 1108 EIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTGCGG 1167
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
L+ + + Y Y S ++C W +++ +L F F LE NC DY+
Sbjct: 1168 NLTTSSGT---FISPNYPMPYYHS-SECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYL 1223
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
V+ CG + PP I S+ +++ ++ RTD+ +GF A Y+
Sbjct: 1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR 1275
Score = 121 bits (292), Expect = 7e-27
Identities = 70/233 (30%), Positives = 105/233 (45%), Gaps = 10/233 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++T G I SP +P YP + C W I L F VFE+ C D+V
Sbjct: 817 CGDELT-GEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVE 875
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGGY 483
I + +CG+ +P + + N +Y+ F S + GF+A S ACG
Sbjct: 876 IGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L TE + S N Y +C W+I NH + L F TF LE NC DY++
Sbjct: 936 L--TESTGTIQSPGH--PNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLE 991
Query: 544 VFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
V+ +CG +PP + S+ +L++ F TD L ++GF +Y+ +
Sbjct: 992 VYDTDSETSLGR--YCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAI 1042
Score = 117 bits (282), Expect = 1e-25
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 1623 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 1682
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 1683 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 1742
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 1743 YMAEGI---FNSPGYPD-IYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVEI 1798
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 1799 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 1850
Score = 113 bits (272), Expect = 2e-24
Identities = 68/225 (30%), Positives = 111/225 (49%), Gaps = 13/225 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G I SPNYP AY + C W GH I L F+ F++EPH CA+D VT+ +G S +
Sbjct: 2698 GVITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPES 2757
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST---ACGG-YLSATEEVK 491
+G +CG+ P + + NQ+ + F SD S+Q GF AT +T CGG + S ++
Sbjct: 2758 PIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIR 2817
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFEL--EREANCRYDYVQVFX-XX 548
+ + +N SR C W ++ ++++F L + C+ +V+V+
Sbjct: 2818 SPHWPQNFPEN---SR--CSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
T CG P +++ S F++ ++ +GFSAS+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPA-QGFSASF 2916
Score = 111 bits (268), Expect = 6e-24
Identities = 67/236 (28%), Positives = 109/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 1390 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 1449
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 1450 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 1509
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I R H V L F F+LE + +C
Sbjct: 1510 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC-- 1563
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 1564 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 1617
Score = 111 bits (267), Expect = 7e-24
Identities = 66/236 (27%), Positives = 107/236 (45%), Gaps = 6/236 (2%)
Query: 359 KHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ 418
K ++ C +T GTI SP +P YP +C W P H I L+F F LE H
Sbjct: 924 KFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHY 983
Query: 419 ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS- 477
C D++ +YD S +LG +CG +P + +S N + +VF +D + +GFL +
Sbjct: 984 NCTNDYLEVYDTDSE--TSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEA 1041
Query: 478 -TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
+A L + ++ + +N Y + +C + I + + F F LE
Sbjct: 1042 ISAATACLQDYTDDLGTFTSPNFPNN-YPNNWECIYRITVRTGQLIAVHFTNFSLEEAIG 1100
Query: 537 CRY-DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSA 591
Y D++++ F G +PP I+S S L ++F++D GFSA
Sbjct: 1101 NYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 104 bits (249), Expect = 1e-21
Identities = 64/231 (27%), Positives = 108/231 (46%), Gaps = 13/231 (5%)
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDG 430
V +G + S YP Y + C W T G+ + F F+LE H C+ D++ +YDG
Sbjct: 1284 VNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDG 1343
Query: 431 ASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYLSATE 488
+ +G +CG LP + +++ ++ +DG +R KGF + CGG LS
Sbjct: 1344 P----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGAT 1399
Query: 489 EVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXX 548
+S + N Y +C W I ++LT F++E + C +D ++++
Sbjct: 1400 GS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGP 1455
Query: 549 XXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 1456 DFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 103 bits (248), Expect = 1e-21
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 12/236 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 2511
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 2512 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 2571
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTFELEREANCRY 539
G L T E + S G Y +C+W + P N + + F F LE +C++
Sbjct: 2572 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQF 2630
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMP--PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D ++ F CG P P ++ S+ + + F T++ + GF A Y
Sbjct: 2631 DVLE-FRVGDADGPLMWRLCGPSKPTLPLVIPYSQ-VWIHFVTNERVEHIGFHAKY 2684
Score = 103 bits (246), Expect = 3e-21
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 9/227 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + T P G +F P + + CV+ G +I++ F EL+ + + +++
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIE 767
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSA 486
+ DG + LG CG+ + + N +++ FK D SV++ F A + ACG L+
Sbjct: 768 VRDGETL----LGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQVACGDELTG 823
Query: 487 TEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFX 546
++ + + N Y C W I P++ + L F FE+ A+C DYV++
Sbjct: 824 EGVIR-----SPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGS 878
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG +P I S L V F S GF A +
Sbjct: 879 SSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKF 925
Score = 101 bits (241), Expect = 1e-20
Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 15/277 (5%)
Query: 323 DVDECAEN---NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIF 379
+++EC N NGG C + + + C C +T + C ++ +G+
Sbjct: 432 NINECLSNPCLNGGT---CVDGVDSFSCECTRLWT--GALCQVPQQVCGESLSGINGSFS 486
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLG 439
+ Y +C W T G +++ F F LE C ++ + +YDG S+ LG
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLG 546
Query: 440 IFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLA---THSTACGGYLSATEEVKHLYSH 496
FCGS LPH +++S N +Y S+ +GF T CGG L T + S
Sbjct: 547 RFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPECGGIL--TGPYGSIKSP 604
Query: 497 ARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXX 556
G+ Y DC W + + V TF T LE +C DY+++
Sbjct: 605 GYPGN--YPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLG 662
Query: 557 TFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
FC P + +T + F +D + +GF +Y
Sbjct: 663 KFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 1577 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 1634
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 1635 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 1694
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 1695 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 1738
Score = 100 bits (239), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 1738 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVE 1797
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 1798 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 1853
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 1854 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 1913
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 1914 DGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 99.1 bits (236), Expect = 4e-20
Identities = 60/226 (26%), Positives = 107/226 (47%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 1991 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 2049
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 2050 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 2106
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ ++
Sbjct: 2107 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSPP 2165
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 2166 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 2211
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 2161 IYSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 2220
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 2221 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 2280
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 2281 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 2335
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/220 (25%), Positives = 100/220 (45%), Gaps = 10/220 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D G + SP +P Y KDC + H I L F+ +E EC D +
Sbjct: 3395 CNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLE 3454
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF--LATHS-TACGGY 483
+ +G++++ LG +CG+ LP+ V + N++Y+ FKSD +G+ + T S + CGG
Sbjct: 3455 VRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGT 3514
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQ 543
L + ++ Y Y + C+W + AP V + F ++ +C +Y+
Sbjct: 3515 LYGD---RGSFTSPGY-PGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLT 3570
Query: 544 VFXXXXXXXXXXXTFCG--IKMPPEIVSTSEALLVRFRTD 581
++ +CG + P V++S + ++F D
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAP-FVASSNQVFIKFHAD 3609
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 1347 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 1405
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 1406 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 1465
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 1466 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 1513
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 2036
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 2037 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 2096
Query: 169 SIDHG 173
D G
Sbjct: 2097 HADRG 2101
Score = 95.5 bits (227), Expect = 5e-19
Identities = 57/157 (36%), Positives = 85/157 (54%), Gaps = 6/157 (3%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDI----EVDSNGHL 62
LGR CG P + S+G+ L +V+ L + GF YEA+ D G
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLA-YEGFLINYEAISAATACLQDYTDDLGTF 1059
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY-DKVKVRDGDSMDSPL 121
SPN+P++Y N CI++++V +A+ F +F +E Y D +++RDG SPL
Sbjct: 1060 TSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPL 1119
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSA 158
+G+F G +PP I S SNKL + F+SD ++GFSA
Sbjct: 1120 LGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 95.5 bits (227), Expect = 5e-19
Identities = 51/167 (30%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Query: 9 RLCGSGKG--PMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPN 66
+ CG P+ S+ S V+++ G+ + R + A C D + G+L SP
Sbjct: 3352 QFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQIADCNRDYH-KAFGNLRSPG 3410
Query: 67 YPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFC 126
+PD+Y +K C L+ PQ++ ++L FHS +EN C D ++VR+G + +SPL+G +C
Sbjct: 3411 WPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYC 3470
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHG 173
G +P + S +N+L + F+SDS G+ + C +G
Sbjct: 3471 GTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGCGGTLYG 3517
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 1689 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 1746
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 1747 GIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 1805
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 1806 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 1851
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 2173 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 2231
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 2232 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 2291
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 2292 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 2331
Score = 92.3 bits (219), Expect = 5e-18
Identities = 60/235 (25%), Positives = 102/235 (43%), Gaps = 13/235 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQ----ECAY 422
C + T P G I SPNYP Y +C + P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 423 DHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-TACG 481
D V I G S CG ++P + + + F S+ + GF ++ +CG
Sbjct: 2980 DGVHIIRGYSVMSTPFATVCGDEMP-APLTIAGPVLLNFYSNEQITDFGFKFSYRIISCG 3038
Query: 482 GYLSATEEV--KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
G + + + YS+A Y ++ + C + I + ++L F F++ +C +
Sbjct: 3039 GVFNFSSGIITSPAYSYADYPNDMH-----CLYTITVSDDKVIELKFSDFDVVPSTSCSH 3093
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+ ++ FCG K PP + S++ ++L+ F+TD KG+ S++
Sbjct: 3094 DYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFR 3148
Score = 91.9 bits (218), Expect = 6e-18
Identities = 53/159 (33%), Positives = 79/159 (49%), Gaps = 7/159 (4%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
LGR CGS + S+ + L +Y LR RGF +E CGG I G +
Sbjct: 545 LGRFCGSSLPHELLSSDNALYFHLYSEHLR--NGRGFTVRWETQQPECGG-ILTGPYGSI 601
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
+SP YP +Y P + C+W + D V F + +E+HD C+ D +++RDG PL+
Sbjct: 602 KSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLL 661
Query: 123 GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
G FC P +++T + F SDS + GF T++
Sbjct: 662 GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITYL 700
Score = 91.9 bits (218), Expect = 6e-18
Identities = 54/167 (32%), Positives = 90/167 (53%), Gaps = 13/167 (7%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV------CGGDIEVDS 58
P+LG+ CGS + P ++S+ + + +V++ + +G++ + CGG + S
Sbjct: 3107 PLLGKFCGSKRPPNVKSSNNSMLLVFKTD-SFQTAKGWKMSFRQTLGPQQGCGGYL-TGS 3164
Query: 59 NGHLESPNYPDD--YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT---CSYDKVKVRD 113
N SP+ + Y N C+W + P + + L F++F +E T C YD VK+ D
Sbjct: 3165 NNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTRQRCLYDYVKLYD 3224
Query: 114 GDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
GDS ++ L G FCG +P S+ N L V F SD T+++ GF+AT+
Sbjct: 3225 GDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Score = 90.6 bits (215), Expect = 1e-17
Identities = 65/249 (26%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 352 GFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV 411
GFT+ + + ++ C +T P+G+I SP YP YP +DCVW T+P + F
Sbjct: 578 GFTV---RWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634
Query: 412 FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKG 471
LE H +C D++ I DG LG FC + + + + F SD + +G
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 694
Query: 472 FLATHSTA-----CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
F T+ T+ CGG + T+ L+ G + C + ++ P+ +++ F
Sbjct: 695 FHITYLTSPSDLRCGG--NYTDPEGELFLPELSGP--FTHTRQCVYMMKQPQGEQIQINF 750
Query: 527 LTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
EL+ +++ +Y++V CG I S + ++ +RF+ D S+
Sbjct: 751 THVELQCQSDSSQNYIEV----RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEK 806
Query: 587 KGFSASYQM 595
F A YQ+
Sbjct: 807 ASFRAVYQV 815
Score = 89.0 bits (211), Expect = 4e-17
Identities = 50/160 (31%), Positives = 80/160 (50%), Gaps = 5/160 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNG 60
+P+LG GS P + S ++L + ++ ++ GF A+++ CGG++ S+G
Sbjct: 1117 SPLLGIFYGSNLPPTIISHSNKLWLKFKSD-QIDTRSGFSAYWDGSSTGCGGNLTT-SSG 1174
Query: 61 HLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
SPNYP Y + C W L L F F +E+H C+ D + V DG S +S
Sbjct: 1175 TFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHPNCTLDYLAVYDGPSSNSH 1234
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+ CG + PP IRS+ + + + +D Q GF A +
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 2289 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 2346
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 2347 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 2405
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 2406 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 2452
Score = 87.8 bits (208), Expect = 1e-16
Identities = 40/121 (33%), Positives = 71/121 (58%), Gaps = 1/121 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVE 99
GF+ Y + G + S+G + SP Y PN + C++ ++V D + L+F F+V
Sbjct: 3027 GFKFSYRIISCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVV 3086
Query: 100 NHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSAT 159
+CS+D + + DG + PL+G FCG K PP+++S++N +L++F++DS G+ +
Sbjct: 3087 PSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMS 3146
Query: 160 F 160
F
Sbjct: 3147 F 3147
Score = 86.2 bits (204), Expect = 3e-16
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESP 65
+LG++CG+G ++S + + + ++ ++ FRA Y+ CG E+ G + SP
Sbjct: 774 LLGKVCGNGTISHIKSITNSVWIRFKIDASVEK-ASFRAVYQVACGD--ELTGEGVIRSP 830
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y + C W + PQ + L F FE+ + C D V++ + SP +
Sbjct: 831 FFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSSAHCETDYVEIGSSSILGSPENKKY 890
Query: 126 CGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
CG IP I S N L V F S+ + GF A F E C I
Sbjct: 891 CGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSAEDLACGEI 935
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 1619 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 1674
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 1675 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 1733
Query: 323 DVDEC 327
V C
Sbjct: 1734 SVSAC 1738
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA--VCGGDIEVDSNGH 61
+P + CG+ + S + L V + + H GF A + A + G+I +S G
Sbjct: 884 SPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENH-GFMAKFSAEDLACGEILTESTGT 942
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPL 121
++SP +P+ Y C W + V ++ + L F +F +E H C+ D ++V D DS S
Sbjct: 943 IQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-- 1000
Query: 122 IGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+G +CG IPP + S+ N L+++F +DS + GF
Sbjct: 1001 LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGF 1035
Score = 85.0 bits (201), Expect = 7e-16
Identities = 50/137 (36%), Positives = 69/137 (50%), Gaps = 9/137 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG G +G ITSP++P Y L +C W + AP H ITL F+ FD+E + C +
Sbjct: 2689 CGGIQIGDSGVITSPNYPNAYDSLTHCSWLLEAPQGHTITLTFSDFDIEPH----TTCAW 2744
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
DSVTV + G+ G +CG + P + S + L V F SD S+ GF A +
Sbjct: 2745 DSVTVRNG-GSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGFYATWNTQTL 2803
Query: 326 ECAENNGGCQHECHNTL 342
C GG H + T+
Sbjct: 2804 GC----GGIFHSDNGTI 2816
Score = 82.6 bits (195), Expect = 4e-15
Identities = 55/164 (33%), Positives = 85/164 (51%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 1459 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 1517
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V + ++V L F F++E D+C + DG S
Sbjct: 1518 S-GEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEPQDSC----IMAYDGLSS 1572
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 1573 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 82.2 bits (194), Expect = 5e-15
Identities = 47/144 (32%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-GHLES 64
+L +LCG K P++RS+G + + + + RGF+A Y C + V+ G LES
Sbjct: 1235 LLTQLCGDEKPPLIRSSGDSMFIKLRTD-EGQQGRGFKAEYRQTCENVVIVNQTYGILES 1293
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGM 124
YP+ Y N+ C W + V F +F++E+H CS D +++ DG +G
Sbjct: 1294 IGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYDGPRQ----MGR 1349
Query: 125 FCGHKIPPDIRSTSNKLLVIFESD 148
+CG +PP +TS+KL V+ +D
Sbjct: 1350 YCGVDLPPPGSTTSSKLQVLLLTD 1373
Score = 81.8 bits (193), Expect = 7e-15
Identities = 47/122 (38%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 203 ENACGGALYGPNGTITSPSFPE--LYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
+ CGG L G N T SP +Y NC+W I+AP I L F F LE +
Sbjct: 3154 QQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAAST-R 3212
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
Q C YD V ++ ++ G FCG+ +P P S G+ L VQF SD ++ R GF A Y
Sbjct: 3213 QRCLYDYVKLYDG-DSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 321 YI 322
I
Sbjct: 3272 TI 3273
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 2406 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 2463
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 2464 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 2523
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 2524 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Score = 81.0 bits (191), Expect = 1e-14
Identities = 43/118 (36%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W I++ P +R+ L+F F LE + Q+C
Sbjct: 1736 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIISSPGNRLQLSFISFQLEDS----QDC 1791
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 1792 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 1847
Score = 79.8 bits (188), Expect = 3e-14
Identities = 56/184 (30%), Positives = 92/184 (50%), Gaps = 16/184 (8%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 2519 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 2576
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQ--DYQVALRFHSFEVENHDTCSYDKVKVR 112
G+ SP Y +Y N C W LS P + +++ F F +E+H C +D ++ R
Sbjct: 2577 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFDVLEFR 2636
Query: 113 DGDSMDSPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASID 171
GD+ D PL+ CG P + +++ + F ++ V+ GF A + F +C I
Sbjct: 2637 VGDA-DGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKY--SFTDCGGIQ 2693
Query: 172 HGCS 175
G S
Sbjct: 2694 IGDS 2697
Score = 76.2 bits (179), Expect = 3e-13
Identities = 61/238 (25%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEP--HQECAYD 423
GC +GTI SP++P +P C W T +++ F+ L P +C
Sbjct: 2804 GCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNS 2863
Query: 424 HVTIYDGA-SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
V ++ G D L CG+ P V+ N VF+S +GF A+ + CG
Sbjct: 2864 FVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASFVSRCGS 2922
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA----NCR 538
+ Y + Y++ +C + IEA V LTF++F LE + +C
Sbjct: 2923 NFTGPSG----YIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCV 2978
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
D V + T CG +MP + LL F +++ + GF SY+++
Sbjct: 2979 NDGVHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVLL-NFYSNEQITDFGFKFSYRII 3035
Score = 75.8 bits (178), Expect = 4e-13
Identities = 41/116 (35%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L GP G+I SP +P YPP ++C+W +V P +T F LE + +C
Sbjct: 590 CGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLE----HHDDCNK 645
Query: 266 DSVTVH-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + + L D L G FC T PP+ + G R+ F SD + GF Y
Sbjct: 646 DYLEIRDGPLYQDPLL--GKFCTTFSVPPLQTTGPFARIHFHSDSQISDQGFHITY 699
Score = 75.8 bits (178), Expect = 4e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 1842 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 1901
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 1902 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGF 1956
Score = 74.9 bits (176), Expect = 8e-13
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L GTI SP P +YP NC W I+ P H I L F F LE + C
Sbjct: 931 ACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLE----FHYNCT 986
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + V+ D G +CG ++PP +TS G+ L + F +D + GF Y
Sbjct: 987 NDYLEVYD---TDSETSLGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 2205 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 2262
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 2263 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 2317
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 2318 SDNSPTHVGFKAKYSI 2333
Score = 71.3 bits (167), Expect = 1e-11
Identities = 42/161 (26%), Positives = 80/161 (49%), Gaps = 11/161 (6%)
Query: 5 PVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFY-----EAVCGGDIEVDSN 59
P+LG+ C + P +++TG + + ++ +GF Y + CGG+ D
Sbjct: 659 PLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISD-QGFHITYLTSPSDLRCGGNY-TDPE 716
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L P + + C++ + PQ Q+ + F E++ S + ++VRDG++
Sbjct: 717 GELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVELQCQSDSSQNYIEVRDGET--- 773
Query: 120 PLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
L+G CG+ I+S +N + + F+ D++V+KA F A +
Sbjct: 774 -LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVY 813
Score = 70.9 bits (166), Expect = 1e-11
Identities = 46/166 (27%), Positives = 82/166 (49%), Gaps = 9/166 (5%)
Query: 2 PDAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDS 58
P++P++G+ CG+ ++S ++L V + L+ GF A + CGG D
Sbjct: 2755 PESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGG-GFYATWNTQTLGCGGIFHSD- 2812
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHD-TCSYDKVKVRDG-D 115
NG + SP++P ++ N C W + + + F ++F + + D C VKV G +
Sbjct: 2813 NGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSFVKVWAGTE 2872
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
+D L+ CG+ P + + SN +F+S + GFSA+F+
Sbjct: 2873 EVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASFV 2917
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 8/227 (3%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
G ++ T I SPN C W + P ++K+ +L Q+C +++
Sbjct: 3279 GGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTS-QDCTQNYL 3337
Query: 426 TIYDGASADVKTLGIFCG---SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGG 482
+ D + FCG S +P + +S + ++FKS G V R ++
Sbjct: 3338 QLQDSPQGHGNSRFQFCGRNASAVP-VFYSSMSTAMVIFKS-GVVNRNSRMSFTYQIADC 3395
Query: 483 YLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYV 542
+ +L S + DN Y++ DC + AP+NH + L F + +E CR D++
Sbjct: 3396 NRDYHKAFGNLRSPG-WPDN-YDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFL 3453
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+V +CG +P + S + L +RF++D +G+
Sbjct: 3454 EVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 68.9 bits (161), Expect = 5e-11
Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 14/160 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACG L G G I SP FP +YP + C W I P I LNFT F++ + CE
Sbjct: 816 ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGSS----AHCE 870
Query: 265 YDSVTVHSK--LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D V + S LG+ ++ +CGT +P +TS + L V F S GF A +
Sbjct: 871 TDYVEIGSSSILGSPENKK---YCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFSA 927
Query: 323 DVDEC----AENNGGCQHECHNTLGGYECACHSGFTLHPN 358
+ C E+ G Q H + + C + PN
Sbjct: 928 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPN 967
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 1391 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 1446
Query: 266 DSVTVHSKLGADVLR-RHGAFCGTALPP---PVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 1447 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 1504
Query: 322 IDVDEC 327
C
Sbjct: 1505 AVTGGC 1510
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 2047 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 2104
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 2105 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSP 2164
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 2165 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 2210
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 1977 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 2031
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 2032 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 2089
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 8/163 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSN 59
++P+LG+ CG+ + S + L + ++ + RG+ + + CGG + D
Sbjct: 3462 NSPLLGKYCGTLLPNPVFSQNNELYLRFKSD-SVTSDRGYEIIWTSSPSGCGGTLYGD-R 3519
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YP Y N C W L P V + F+ +++ C + + + DG + S
Sbjct: 3520 GSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYLTLYDGPNASS 3579
Query: 120 PLIGMFCG--HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P G +CG I P + S SN++ + F +D + + F T+
Sbjct: 3580 PSSGPYCGGDTSIAPFVAS-SNQVFIKFHADYARRPSAFRLTW 3621
Score = 62.1 bits (144), Expect = 6e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 1510 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRYHRVLLNFTDFDLEP----QDSC-- 1563
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 1564 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 1616
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 2452 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 2507
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 2508 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 2567
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 2568 AVCGGSLPNTPEGNFTSPGYD 2588
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/118 (33%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CG GP+G I SP++P+ Y NC + I A P + L F F LE C
Sbjct: 2920 CGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVN 2979
Query: 266 DSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
D VH G V+ CG +P P+T G VL + F S+ + GF Y I
Sbjct: 2980 DG--VHIIRGYSVMSTPFATVCGDEMPAPLTIAGPVL-LNFYSNEQITDFGFKFSYRI 3034
Score = 61.3 bits (142), Expect = 1e-08
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 190 DIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFT 249
D GYE+ + CGG LYG G+ TSP +P YP C W +VAP +T+NF
Sbjct: 3497 DRGYEIIWTSSP--SGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFY 3554
Query: 250 HFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCG--TALPPPVTSDGSVLRVQFTS 307
++ +C + +T++ A G +CG T++ P V S V ++F +
Sbjct: 3555 FISIDD----PGDCVQNYLTLYDGPNAS-SPSSGPYCGGDTSIAPFVASSNQVF-IKFHA 3608
Query: 308 DGSVHRSGF 316
D + S F
Sbjct: 3609 DYARRPSAF 3617
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 2336 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 2391
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 2392 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 2448
Query: 324 VDEC 327
++EC
Sbjct: 2449 MEEC 2452
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC + G+ SP YP YP C W G + + F ++ +C +++
Sbjct: 3510 GCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISIDDPGDCVQNYL 3569
Query: 426 TIYDGASADVKTLGIFCGSKLPHL-VMASQNQMYMVFKSDGSVQRKGFLAT 475
T+YDG +A + G +CG +AS NQ+++ F +D + + F T
Sbjct: 3570 TLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAFRLT 3620
Score = 58.4 bits (135), Expect = 7e-08
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 1/124 (0%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
+ VCG + NG + Y + C W + + + F F +E+ D C +
Sbjct: 471 QQVCGESLS-GINGSFSYRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+ ++V DGDS + +G FCG +P ++ S+ N L S+ GF+ + + E
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPE 589
Query: 167 CASI 170
C I
Sbjct: 590 CGGI 593
Score = 57.6 bits (133), Expect = 1e-07
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGH 61
D +L CG+ GP++ + + T V+Q + P +GF A + + CG + S G+
Sbjct: 2875 DKALLATGCGNVAPGPVITPSNT-FTAVFQS--QEAPAQGFSASFVSRCGSNFTGPS-GY 2930
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSM 117
+ SPNYP Y N C + + V L F SF +E +C D V + G S+
Sbjct: 2931 IISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSV 2990
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S CG ++P + + + +L+ F S+ + GF ++
Sbjct: 2991 MSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 3032
Score = 56.0 bits (129), Expect = 4e-07
Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CG LS + +S+ R D Y +C W I+ +++TF F LE NC +
Sbjct: 474 CGESLSG---INGSFSY-RSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLESMDNCPH 529
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
+++QV+ FCG +P E++S+ AL ++ +GF+ ++ +P
Sbjct: 530 EFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQP 588
Score = 55.2 bits (127), Expect = 7e-07
Identities = 43/164 (26%), Positives = 73/164 (44%), Gaps = 8/164 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD-S 58
+A + G CGS S+G+ LTV + L L+ GF A Y + CGG +
Sbjct: 3229 NANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLE-REGFNATYTIMDMPCGGTYNATWT 3287
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
++ SPN D P +C W + P QV + + ++ + D C+ + ++++D
Sbjct: 3288 PQNISSPNSSDPDVPFSICTWVIDSPPHQQVKITVWALQLTSQD-CTQNYLQLQDSPQGH 3346
Query: 119 SPLIGMFCGHKIP--PDIRSTSNKLLVIFESDSTVQKAGFSATF 160
FCG P S+ + +VIF+S + + S T+
Sbjct: 3347 GNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTY 3390
Score = 54.4 bits (125), Expect = 1e-06
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 10/142 (7%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ ++ + AC GT TSP+FP YP C++ I I ++FT+F
Sbjct: 1034 GFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNF 1093
Query: 252 DLE---GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
LE GN+ Y G + G F G+ LPP + S + L ++F SD
Sbjct: 1094 SLEEAIGNY-------YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSD 1146
Query: 309 GSVHRSGFAAVYYIDVDECAEN 330
RSGF+A + C N
Sbjct: 1147 QIDTRSGFSAYWDGSSTGCGGN 1168
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP +P+ Y K+C + AP H I+L F +E + EC D + V +
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENS----VECRNDFLEVRNGS 3459
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
++ G +CGT LP PV S + L ++F SD G+ ++ C
Sbjct: 3460 NSNSPLL-GKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSGC 3511
Score = 50.8 bits (116), Expect = 1e-05
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 1856 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 1911
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT +S G+ L F SD S+ GF ++
Sbjct: 1912 IYD--GPSIHARLIGAYCGTQ-TESFSSTGNSLTFHFYSDSSISGKGFLLEWF 1961
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 7/129 (5%)
Query: 192 GYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHF 251
G+ + DG CGG L +GT SP++P Y C W + + L F F
Sbjct: 1153 GFSAYWDGSS--TGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDF 1210
Query: 252 DLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
LE + C D + V+ ++ CG PP + S G + ++ +D
Sbjct: 1211 HLE----HHPNCTLDYLAVYDGPSSN-SHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQ 1265
Query: 312 HRSGFAAVY 320
GF A Y
Sbjct: 1266 QGRGFKAEY 1274
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/109 (30%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + S +P Y ++C W I A + + F FDLE +H+ C D + ++
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLE-HHI---NCSTDYLELY--- 1341
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 1342 --DGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 1388
Score = 48.8 bits (111), Expect = 6e-05
Identities = 32/106 (30%), Positives = 51/106 (48%), Gaps = 8/106 (7%)
Query: 205 ACGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+CGG +G ITSP++ YP +CL+ I I L F+ FD+ + C
Sbjct: 3036 SCGGVFNFSSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDV----VPSTSC 3091
Query: 264 EYDSVTVHSKLG-ADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSD 308
+D + ++ +D L G FCG+ PP V S + + + F +D
Sbjct: 3092 SHDYLAIYDGANTSDPLL--GKFCGSKRPPNVKSSNNSMLLVFKTD 3135
Score = 48.4 bits (110), Expect = 8e-05
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE---NACGGALYGPNGTIT 218
+ +EC S +CV+ + + C C + G C+ CG +L G NG+ +
Sbjct: 431 ENINECLSNPCLNGGTCVDGVDSFSCECTRLWT----GALCQVPQQVCGESLSGINGSFS 486
Query: 219 SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADV 278
S Y NC W I + + FT F LE C ++ + V+ +
Sbjct: 487 YRSPDVGYVHDVNCFWVIKTEMGKVLRITFTFFRLES----MDNCPHEFLQVYDGDSSSA 542
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC 327
+ G FCG++LP + S + L S+ + GF + EC
Sbjct: 543 FQL-GRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRWETQQPEC 590
Score = 46.8 bits (106), Expect = 2e-04
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + NGTI SP +P+ +P C W + + ++F + L + Q + +
Sbjct: 2805 CGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISFDNNFLIPSGDGQCQNSF 2864
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
V ++ L G CG P PV + + F S GF+A + V
Sbjct: 2865 VKVWAGTEEVDKALLATG--CGNVAPGPVITPSNTFTAVFQSQ-EAPAQGFSASF---VS 2918
Query: 326 ECAENNGG 333
C N G
Sbjct: 2919 RCGSNFTG 2926
Score = 46.4 bits (105), Expect = 3e-04
Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P G + P + + C++ + P +I +NFTH +L +C+
Sbjct: 708 CGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQINFTHVEL--------QCQS 759
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
DS + ++ D G CG + S + + ++F D SV ++ F AVY +
Sbjct: 760 DSSQNYIEV-RDGETLLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV 815
Score = 33.9 bits (74), Expect = 1.8
Identities = 53/218 (24%), Positives = 81/218 (37%), Gaps = 21/218 (9%)
Query: 150 TVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGK-KCENACG 207
TV K S+ + C ++ C G C+ D+ E++S C+N G
Sbjct: 130 TVDKKVCSSNPCQNGGNCLNLHDSFFCICPPQWKGPLCSADVNECEIYSGTPLSCQN--G 187
Query: 208 GALYGPNGTITSPSFPELYPP-----LKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
G G+ + PE Y P +C VA H I + + G Y
Sbjct: 188 GTCVNTMGSYSCHCPPETYGPQCASKYDDCEGGSVARCVHGICEDLMR-EQAGEPKYSCV 246
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C+ ++ + + R +F P P ++ Q + +G+ YI
Sbjct: 247 CDAGWMSSPNSPACTLDRDECSF----QPGPCSTLVQCFNTQGSFYCGACPTGWQGNGYI 302
Query: 323 --DVDECAENNGGCQ----HECHNTLGGYEC-ACHSGF 353
D++EC NNGGC EC NT G C AC G+
Sbjct: 303 CEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGY 340
>AB209880-1|BAD93117.1| 1327|Homo sapiens cubilin variant protein.
Length = 1327
Score = 139 bits (336), Expect = 3e-32
Identities = 111/400 (27%), Positives = 174/400 (43%), Gaps = 54/400 (13%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQEC 263
+CGG L+ G ITSP +PE YP NC W ++ I ++F F + +
Sbjct: 797 SCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQG 856
Query: 264 EY----DSVTVHS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAA 318
+Y + ++S LG +G FCG+ + + + + VQF SD S GF
Sbjct: 857 DYLVLRNGPDIYSPPLGPP--GGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKI 914
Query: 319 VYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTI 378
Y C GG + H+ A +G+ PN PH
Sbjct: 915 KYEAKSLAC----GGNVY-IHD-------ADSAGYVTSPNH--------------PH--- 945
Query: 379 FSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQECAYDHVTIYDGASADVKT 437
NYP DC+W + P RI+L F + F++E C +++ + DG +D
Sbjct: 946 ---NYP----PHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAPI 998
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA-CGGYLSATEEVKHLYSH 496
L FCG+ LP +S MY+ F+SD S GF A +S A CGG + V H
Sbjct: 999 LSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGH 1058
Query: 497 AR--YGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXX 554
Y DN + C+W+++ H++ ++F F L+ + C D+V+++
Sbjct: 1059 PTLPYRDNLF-----CEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIW-DNHTSGNI 1112
Query: 555 XXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+CG +P I ++S +VRF TD S+ GF ++
Sbjct: 1113 LGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE 1152
Score = 137 bits (332), Expect = 1e-31
Identities = 80/228 (35%), Positives = 113/228 (49%), Gaps = 11/228 (4%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GGC P G I SPNYP+ Y + DC W HR+ L F F+LE C
Sbjct: 214 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLESQDSC---- 269
Query: 425 VTIYDGASADVKTLGIFCG-SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGY 483
+ YDG S+ + L CG +L + +++S N +++ F+S S Q +GF A ACGG+
Sbjct: 270 IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFRQACGGH 329
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEA--PRNHFVKLTFLTFELEREANCRYDY 541
+ + S R+ N Y + +C W I+A P NH + L+F FELER C D+
Sbjct: 330 ILTSS--FDTVSSPRFPAN-YPNNQNCSWIIQAQPPLNH-ITLSFTHFELERSTTCARDF 385
Query: 542 VQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
V++ +CG MP I S S AL +RF +D S+ GF
Sbjct: 386 VEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF 433
Score = 118 bits (283), Expect = 8e-26
Identities = 72/233 (30%), Positives = 110/233 (47%), Gaps = 10/233 (4%)
Query: 369 HDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG-HRIKLIFNVFELEPHQECAYDHVTI 427
H +T T+ SP +PA YP ++C W P + I L F FELE CA D V I
Sbjct: 329 HILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEI 388
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS---TACGGYL 484
DG D G +CG+ +PH + + + + + F SD S+ GF T + +ACGG
Sbjct: 389 LDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSACGGTF 448
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
E + ++ Y D Y +C WNI + + ++L+F++F+LE +C D+V++
Sbjct: 449 YMAEGI---FNSPGYPD-IYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEI 504
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVS-TSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG P S L VRF +D S GF A++ +
Sbjct: 505 -REGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKI 556
Score = 115 bits (277), Expect = 4e-25
Identities = 68/236 (28%), Positives = 110/236 (46%), Gaps = 15/236 (6%)
Query: 366 GCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHV 425
GC +++ G+ SP +P YP K+C+W T PG I+L + F++E H C +D +
Sbjct: 96 GCGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVL 155
Query: 426 TIYDGASADVKTLGIFCGSKLPH---LVMASQNQMYMVFKSDGSVQRKGFLATHST---A 479
IY G + C + P V ++ N++ + FK+D S+ +GF A+
Sbjct: 156 EIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGG 215
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG A H ++ + Y S DC W I RNH V L F F+LE + +C
Sbjct: 216 CGGIFQAPSGEIHSPNY----PSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLESQDSC-- 269
Query: 540 DYVQVFXXXXXXXXXXXTFCG-IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
+ + CG ++ IVS+ +L +RF++ S +GF A ++
Sbjct: 270 --IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQFR 323
Score = 101 bits (241), Expect = 1e-20
Identities = 58/164 (35%), Positives = 85/164 (51%), Gaps = 5/164 (3%)
Query: 7 LGRLCGSGK--GPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLES 64
L R CG + P++ S+G+ L + +Q G + +RGFRA + CGG I S + S
Sbjct: 283 LARTCGREQLANPIV-SSGNSLFLRFQSGPS-RQNRGFRAQFRQACGGHILTSSFDTVSS 340
Query: 65 PNYPDDYQPNKLCIWKLSV-PQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG 123
P +P +Y N+ C W + P + L F FE+E TC+ D V++ DG D+PL G
Sbjct: 341 PRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRG 400
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
+CG +P I S S+ L + F SDS++ GF T C
Sbjct: 401 RYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTASVSAC 444
Score = 99 bits (238), Expect = 2e-20
Identities = 62/224 (27%), Positives = 100/224 (44%), Gaps = 6/224 (2%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C + G SP YP YP +CVW ++PG+R++L F F+LE Q+C+ D V
Sbjct: 444 CGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVE 503
Query: 427 IYDGASADVKTLGIFCGSKLP-HLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
I +G +A +G +CG+ P + + +++ F SDGS GF AT G +
Sbjct: 504 IREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIFG---N 559
Query: 486 ATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVF 545
H + + Y ++ W + +H V L ++E NC YD ++++
Sbjct: 560 DNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQNCYYDKLRIY 619
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
+CG + ST +L F +D S+ KGF
Sbjct: 620 DGPSIHARLIGAYCGTQ-TESFGSTGNSLTFHFYSDSSISGKGF 662
Score = 99.1 bits (236), Expect = 4e-20
Identities = 60/226 (26%), Positives = 107/226 (47%), Gaps = 14/226 (6%)
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
+FSP +P +Y R DC W P ++L ++E H+ CAYD + I DG + +
Sbjct: 697 LFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIESHRTCAYDSLVIRDGDNNLAQQ 755
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHLYSHA 497
L + CG ++P + ++ M++ F SD SV R GF A+ +CGGYL A + + +
Sbjct: 756 LAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYLHAD---RGIITSP 812
Query: 498 RYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELER-EANCRY-DYV------QVFXXX 548
+Y + Y S +C W++ + + F F++ +++C DY+ ++
Sbjct: 813 KYPE-TYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSPP 871
Query: 549 XXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
FCG + ++ + V+F +D S +GF Y+
Sbjct: 872 LGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYE 917
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/235 (28%), Positives = 104/235 (44%), Gaps = 13/235 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FEL-EPHQECAY-DHVTIYDGAS 432
G I SP YP YP+ +C W G I + F F++ C D++ + +G
Sbjct: 807 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 866
Query: 433 ADVKTLGI------FCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH---STACGGY 483
LG FCGS + S NQM++ F SD S + +GF + S ACGG
Sbjct: 867 IYSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLACGGN 926
Query: 484 LSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLT-FELEREANCRYDYV 542
+ + Y + + Y ADC W + AP ++L F F++E NC +Y+
Sbjct: 927 VYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYL 986
Query: 543 QVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
++ FCG +P S+ E + +RFR+D+S GF A Y + +
Sbjct: 987 ELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ 1041
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/168 (29%), Positives = 84/168 (50%), Gaps = 5/168 (2%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRA-FYEAVCGGDIEVDSNGHLESP 65
+GR CG P +T S+L V+ + +GF+ ++ CGG++ + G SP
Sbjct: 53 MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELS-GATGSFSSP 111
Query: 66 NYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMF 125
+P+ Y PNK CIW + + L H F+VE H C++D +++ G SP I
Sbjct: 112 GFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQL 171
Query: 126 CGHKIPPD---IRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
C + P + + ST N+L + F++D ++ GF+A++ C I
Sbjct: 172 CTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVTGGCGGI 219
Score = 95.9 bits (228), Expect = 4e-19
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG + D+ L SP +PD Y C W + P D V L S ++E+H TC+YD
Sbjct: 684 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAP-DSTVELNILSLDIESHRTCAYDS 742
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECA 168
+ +RDGD+ + + + CG +IP IRST + + F SDS+V +AGF+A+F K
Sbjct: 743 LVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKSCGGYL 802
Query: 169 SIDHG 173
D G
Sbjct: 803 HADRG 807
Score = 93.9 bits (223), Expect = 2e-18
Identities = 58/166 (34%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDIEVDSN 59
DAP+ GR CG+ + S S LT+ + + GF A CGG + +
Sbjct: 395 DAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAG-GFHTTVTASVSACGGTFYM-AE 452
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SP YPD Y PN C+W + ++ L F SF++E+ CS D V++R+G++
Sbjct: 453 GIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDSQDCSRDFVEIREGNA-TG 511
Query: 120 PLIGMFCGHKIPPDIRS-TSNKLLVIFESDSTVQKAGFSATFMKEF 164
L+G +CG+ P + S + L V F SD + GF ATFMK F
Sbjct: 512 HLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATFMKIF 557
Score = 93.1 bits (221), Expect = 3e-18
Identities = 48/160 (30%), Positives = 87/160 (54%), Gaps = 8/160 (5%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---VCGGDI---EVDSNGH 61
G CGS + ++ +++ V + +GF+ YEA CGG++ + DS G+
Sbjct: 879 GHFCGSHASSTLFTSDNQMFVQFISD-HSNEGQGFKIKYEAKSLACGGNVYIHDADSAGY 937
Query: 62 LESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDKVKVRDGDSMDSP 120
+ SPN+P +Y P+ CIW L+ P + ++ L+F F++E C+ + +++RDG D+P
Sbjct: 938 VTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVDSDAP 997
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ FCG +P S+ + + F SD++ GF A +
Sbjct: 998 ILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKY 1037
Score = 88.6 bits (210), Expect = 6e-17
Identities = 51/167 (30%), Positives = 84/167 (50%), Gaps = 5/167 (2%)
Query: 3 DAPVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYE-AVCGGDIEVDSNGH 61
DAP+L + CG+ S+G + + ++ H GF+A Y A CGG + S G
Sbjct: 995 DAPILSKFCGTSLPSSQWSSGEVMYLRFRSD-NSPTHVGFKAKYSIAQCGGRVPGQS-GV 1052
Query: 62 LESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSP 120
+ES +P Y+ N C W L + + + F F ++N C D V++ D + +
Sbjct: 1053 VESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGN- 1111
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDEC 167
++G +CG+ IP I ++SN +V F +D +V +GF F +EC
Sbjct: 1112 ILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEEC 1158
Score = 88.6 bits (210), Expect = 6e-17
Identities = 62/223 (27%), Positives = 93/223 (41%), Gaps = 10/223 (4%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
G + S +P Y C W GH + + F F L+ C D V I+D ++
Sbjct: 1051 GVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSG 1110
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA---CGGYLSATEEVK 491
LG +CG+ +P + S N + F +DGSV GF ++ CGG L +
Sbjct: 1111 -NILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQGSIGT- 1168
Query: 492 HLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXX 551
++ Y + R C+W I AP + L F L +C ++V VF
Sbjct: 1169 --FTSPNYPNPNPHGRI-CEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSN 1225
Query: 552 XXXXXTFC-GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
C + + EI S+ + V F TD S + GF+ASY
Sbjct: 1226 SPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASY 1268
Score = 85.8 bits (203), Expect = 4e-16
Identities = 50/125 (40%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 205 ACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVA-PPQHRITLNFTHFDLEGNHMYQQE 262
ACGG + + T++SP FP YP +NC W I A PP + ITL+FTHF+LE +
Sbjct: 325 ACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFTHFELERS----TT 380
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C D V + D R G +CGT +P P+TS S L ++F SD S+ GF
Sbjct: 381 CARDFVEILDGGHEDAPLR-GRYCGTDMPHPITSFSSALTLRFVSDSSISAGGFHTTVTA 439
Query: 323 DVDEC 327
V C
Sbjct: 440 SVSAC 444
Score = 85.8 bits (203), Expect = 4e-16
Identities = 52/170 (30%), Positives = 81/170 (47%), Gaps = 8/170 (4%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C D+ GT SPNYP P + C W+ + G RI L+FN L H C +HV
Sbjct: 1158 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVI 1217
Query: 427 IYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----CG 481
+++G ++ L C S + + + +S N M ++F +DGS GF A+++++ CG
Sbjct: 1218 VFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSEDAVCG 1277
Query: 482 GYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR--NHFVKLTFLTF 529
G L T E + S G Y +C+W + P N + + F F
Sbjct: 1278 GSLPNTPE-GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDF 1326
Score = 85.4 bits (202), Expect = 6e-16
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 13/164 (7%)
Query: 4 APVLGRLCG--SGKGPM-MRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVD 57
+P + +LC S + PM + STG+ L + ++ L + RGF A ++AV CGG +
Sbjct: 165 SPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAP 223
Query: 58 SNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
S G + SPNYP Y+ N C W + V ++++V L F F++E+ D+C + DG S
Sbjct: 224 S-GEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLESQDSC----IMAYDGLSS 278
Query: 118 DSPLIGMFCG-HKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ CG ++ I S+ N L + F+S + Q GF A F
Sbjct: 279 TMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 322
Score = 81.4 bits (192), Expect = 9e-15
Identities = 44/118 (37%), Positives = 62/118 (52%), Gaps = 7/118 (5%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
+ACGG Y G SP +P++YPP C+W IV+ P +R+ L+F F LE + Q+C
Sbjct: 442 SACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS----QDC 497
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTS-DGSVLRVQFTSDGSVHRSGFAAVY 320
D V + G G +CG + P +S G L V+F SDGS +GF A +
Sbjct: 498 SRDFVEIRE--GNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF 553
Score = 81.4 bits (192), Expect = 9e-15
Identities = 49/164 (29%), Positives = 83/164 (50%), Gaps = 6/164 (3%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHL 62
+LGR CG+ P T S VV GFR +E+ CGGD++ S G
Sbjct: 1112 ILGRYCGNTI-PDSIDTSSNTAVVRFVTDGSVTASGFRLRFESSMEECGGDLQ-GSIGTF 1169
Query: 63 ESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLI 122
SPNYP+ ++C W+++ P+ ++ L F++ + H +C+ + V V +G +SP +
Sbjct: 1170 TSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHPSCNNEHVIVFNGIRSNSPQL 1229
Query: 123 GMFCGH-KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD 165
C + +I+S+ N + VIF +D + GF+A++ D
Sbjct: 1230 EKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 1273
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/116 (33%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 41 GFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVEN 100
GF+A + + G D V ++G + SP +P++Y N W ++V + V R ++E
Sbjct: 548 GFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEE 607
Query: 101 HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
C YDK+++ DG S+ + LIG +CG + ST N L F SDS++ GF
Sbjct: 608 IQNCYYDKLRIYDGPSIHARLIGAYCGTQ-TESFGSTGNSLTFHFYSDSSISGKGF 662
Score = 74.5 bits (175), Expect = 1e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 192 GYELHSDGKKCENACGGALY----GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
G+++ + K ACGG +Y G +TSP+ P YPP +C+W + APP+ RI L
Sbjct: 911 GFKIKYEAKSL--ACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQ 968
Query: 248 F-THFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFT 306
F FD+E C + + + + +D FCGT+LP S G V+ ++F
Sbjct: 969 FEDRFDIE----VTPNCTSNYLELRDGVDSDA-PILSKFCGTSLPSSQWSSGEVMYLRFR 1023
Query: 307 SDGSVHRSGFAAVYYI 322
SD S GF A Y I
Sbjct: 1024 SDNSPTHVGFKAKYSI 1039
Score = 68.5 bits (160), Expect = 7e-11
Identities = 47/175 (26%), Positives = 82/175 (46%), Gaps = 13/175 (7%)
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQR-KGF-LATHSTACGGYL 484
+YDG + +G +CG LP + +++ ++ +DG +R KGF + CGG L
Sbjct: 46 LYDGP----RQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGEL 101
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
S +S + N Y +C W I ++LT F++E + C +D +++
Sbjct: 102 SGATGS---FSSPGF-PNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEI 157
Query: 545 FXXXXXXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+ C + P ++ ST L +RF+TD S+ +GF+AS+Q V
Sbjct: 158 YGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 212
Score = 68.5 bits (160), Expect = 7e-11
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 10/126 (7%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G G+ +SP FP YPP K C+W I P I L FD+E Y C +
Sbjct: 97 CGGELSGATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVE----YHSRCNF 152
Query: 266 DSVTVHSKLGADVLR-RHGAFCGTALPP---PVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
D + ++ G D R C P V+S G+ L ++F +D S++ GF A +
Sbjct: 153 DVLEIYG--GPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQ 210
Query: 322 IDVDEC 327
C
Sbjct: 211 AVTGGC 216
Score = 68.1 bits (159), Expect = 9e-11
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLE 63
A L LCG +RSTG + + + + GF A + CGG + D G +
Sbjct: 753 AQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVT-RAGFNASFHKSCGGYLHAD-RGIIT 810
Query: 64 SPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHD-TCSY-DKVKVRDGDSMDSP 120
SP YP+ Y N C W + V +A+ F F++ N D +C+ D + +R+G + SP
Sbjct: 811 SPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPDIYSP 870
Query: 121 LI------GMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+ G FCG + ++ N++ V F SD + + GF +
Sbjct: 871 PLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIKY 916
Score = 66.5 bits (155), Expect = 3e-10
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 8/119 (6%)
Query: 205 ACGGALYGPNGTIT--SPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
ACGG L + + SP +P+ Y +C W I AP + LN D+E + +
Sbjct: 683 ACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDS-TVELNILSLDIESH----RT 737
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C YDS+ + ++ ++ CG +P P+ S G + ++FTSD SV R+GF A ++
Sbjct: 738 CAYDSLVIRDG-DNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH 795
Score = 63.3 bits (147), Expect = 3e-09
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 10/116 (8%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE Q C
Sbjct: 216 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLES----QDSC-- 269
Query: 266 DSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + L + + R CG L P+ S G+ L ++F S S GF A +
Sbjct: 270 --IMAYDGL-SSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRAQF 322
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/141 (30%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G GT TSP++P P + C W I AP RITL F + L H C
Sbjct: 1158 CGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRL-ATH---PSCNN 1213
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
+ V V + + ++ + + + S G+ ++V F +DGS GF A Y D
Sbjct: 1214 EHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASYTSSED 1273
Query: 326 ECAENNGGCQHECHNTLGGYE 346
+ E + T GY+
Sbjct: 1274 AVCGGSLPNTPEGNFTSPGYD 1294
Score = 60.9 bits (141), Expect = 1e-08
Identities = 36/124 (29%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG + G +G + S P L Y C W + H +T++F F+L+ + CE
Sbjct: 1042 CGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQNS----SGCE 1097
Query: 265 YDSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYID 323
D V + + ++L G +CG +P + + + V+F +DGSV SGF +
Sbjct: 1098 KDFVEIWDNHTSGNIL---GRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFESS 1154
Query: 324 VDEC 327
++EC
Sbjct: 1155 MEEC 1158
Score = 49.6 bits (113), Expect = 3e-05
Identities = 33/113 (29%), Positives = 49/113 (43%), Gaps = 8/113 (7%)
Query: 210 LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVT 269
+ G +G + SP +PE YP N W + H + D+E Q C YD +
Sbjct: 562 IVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIE----EIQNCYYDKLR 617
Query: 270 VHSKLGADV-LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
++ G + R GA+CGT S G+ L F SD S+ GF ++
Sbjct: 618 IYD--GPSIHARLIGAYCGTQ-TESFGSTGNSLTFHFYSDSSISGKGFLLEWF 667
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/100 (32%), Positives = 49/100 (49%), Gaps = 10/100 (10%)
Query: 3 DAPVLGRLCGS-GKGPMMRSTGSRLTVVY-QPGLRLKPHRGFRAFY----EAVCGGDIEV 56
++P L +LC S ++S+G+ + V++ G R P+ GF A Y +AVCGG +
Sbjct: 1225 NSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSR--PYGGFTASYTSSEDAVCGGSLPN 1282
Query: 57 DSNGHLESPNYPD--DYQPNKLCIWKLSVPQDYQVALRFH 94
G+ SP Y +Y N C W LS P ++ H
Sbjct: 1283 TPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIH 1322
Score = 34.7 bits (76), Expect = 1.0
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHR-SGFAAVYYI 322
Y V++ +L D R+ G +CG LPPP ++ S L+V +DG R GF +++
Sbjct: 37 YGKVSLQFQL-YDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFV 94
>BC033205-1|AAH33205.1| 449|Homo sapiens procollagen
C-endopeptidase enhancer protein.
Length = 449
Score = 138 bits (333), Expect = 7e-32
Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL------ATHSTA- 479
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL AT T
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGTEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP LYPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
>BC000574-1|AAH00574.1| 449|Homo sapiens procollagen
C-endopeptidase enhancer protein.
Length = 449
Score = 138 bits (333), Expect = 7e-32
Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL------ATHSTA- 479
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL AT T
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGTEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP LYPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
>AF083655-1|AAD16041.1| 449|Homo sapiens procollagen C-proteinase
enhancer protein protein.
Length = 449
Score = 138 bits (333), Expect = 7e-32
Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL------ATHSTA- 479
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL AT T
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGTEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP LYPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
>AF053356-10|AAC78800.1| 449|Homo sapiens PCOLCE protein.
Length = 449
Score = 138 bits (333), Expect = 7e-32
Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL------ATHSTA- 479
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL AT T
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGTEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP LYPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
>AB008549-1|BAA23281.1| 449|Homo sapiens type 1 procollagen
C-proteinase enhancer protein protein.
Length = 449
Score = 138 bits (333), Expect = 7e-32
Identities = 81/238 (34%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFL------ATHSTA- 479
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL AT T
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH 156
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGTEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/115 (36%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP LYPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.4 bits (192), Expect = 9e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
>L33799-1|AAA61949.1| 449|Homo sapiens procollagen C-proteinase
enhancer protein protein.
Length = 449
Score = 137 bits (332), Expect = 1e-31
Identities = 79/238 (33%), Positives = 116/238 (48%), Gaps = 13/238 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C DV G + S +P +YP K+C+W + G + L F VF+LE H C YD +
Sbjct: 37 CGGDVKGESGYVASEGFPNSYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALE 96
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS--------- 477
++ G+ + LG FCG+ P ++A NQ+ + +D +GFL +S
Sbjct: 97 VFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGSEH 156
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L E+ + + + ++ Y C W+I AP + + LTF F+LE + C
Sbjct: 157 QFCGGRL---EKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYC 213
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
RYD V VF FCG +P I S LLV+F +D S+ GFSASY+
Sbjct: 214 RYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYK 271
Score = 104 bits (250), Expect = 8e-22
Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L GT+T+P++PE YPP +C W I+APP I L F FDLE + C
Sbjct: 159 CGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTY----CR 214
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YDSV+V + +D RR G FCG A+P ++S+G+ L VQF SD SV GF+A Y
Sbjct: 215 YDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/165 (36%), Positives = 85/165 (51%), Gaps = 13/165 (7%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA---------VCGGDIEVD 57
LGR CG+ + + + G+++T+ RGF +Y CGG +E
Sbjct: 108 LGRFCGTFRPAPLVAPGNQVTLRMTTD-EGTGGRGFLLWYSGRATSGSEHQFCGGRLE-K 165
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGD- 115
+ G L +PN+P+ DY P C W + P D +AL F F++E C YD V V +G
Sbjct: 166 AQGTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAV 225
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
S DS +G FCG +P I S N+LLV F SD +V GFSA++
Sbjct: 226 SDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 83.0 bits (196), Expect = 3e-15
Identities = 37/108 (34%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Query: 49 VCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
+CGGD++ +S G++ S +P+ Y PNK CIW ++VP+ V+L F F++E H C YD
Sbjct: 36 LCGGDVKGES-GYVASEGFPNSYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDA 94
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
++V G +G FCG P + + N++ + +D GF
Sbjct: 95 LEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGF 142
Score = 82.2 bits (194), Expect = 5e-15
Identities = 41/105 (39%), Positives = 59/105 (56%), Gaps = 2/105 (1%)
Query: 376 GTIFSPNYPAA-YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGA-SA 433
GT+ +PN+P + YP C W P I L F F+LEP C YD V++++GA S
Sbjct: 168 GTLTTPNWPESDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSD 227
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
D + LG FCG +P + + N++ + F SD SV GF A++ T
Sbjct: 228 DSRRLGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKT 272
Score = 81.8 bits (193), Expect = 7e-15
Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 5/115 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG + G +G + S FP YPP K C+W I P ++L+F FDLE C Y
Sbjct: 37 CGGDVKGESGYVASEGFPNSYPPNKECIWTITVPEGQTVSLSFRVFDLE----LHPACRY 92
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D++ V + G +R G FCGT P P+ + G+ + ++ T+D GF Y
Sbjct: 93 DALEVFAGSGTSG-QRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGTGGRGFLLWY 146
>AL357673-1|CAH73896.1| 449|Homo sapiens novel transcript protein.
Length = 449
Score = 135 bits (326), Expect = 5e-31
Identities = 79/229 (34%), Positives = 110/229 (48%), Gaps = 8/229 (3%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++ P G SPN+P YP +C W G + L F+ F+LE H C++D +
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89
Query: 427 IYDGASADV-KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH-STACGGYL 484
IY+GAS D LG FCG P +S + M ++F SD V GF A + CGG L
Sbjct: 90 IYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKDVCGGVL 149
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
+ V + Y +N Y + +C W I A VKL F+ F++E C YDYV V
Sbjct: 150 TGLSGV---LTSPEYPNN-YPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAV 205
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG PP +VS L V F++D ++ +GF A Y
Sbjct: 206 LGGPGPTRGHH--YCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYY 252
Score = 113 bits (272), Expect = 2e-24
Identities = 73/251 (29%), Positives = 119/251 (47%), Gaps = 19/251 (7%)
Query: 356 HPNKHDCKEG---GCKHDV-----TLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKL 407
H +KH G G + DV T G + SP YP YP +C W +KL
Sbjct: 126 HSDKHVASHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKL 185
Query: 408 IFNVFELEPHQECAYDHVTIYDGASADVKTLGI-FCGSKLPHLVMASQNQMYMVFKSDGS 466
+F F++E ++EC YD+V + G T G +CGS P +++ +++ +VFKSD +
Sbjct: 186 VFVDFQVEGNEECTYDYVAVLGGPGP---TRGHHYCGSTRPPTLVSLGHELQVVFKSDFN 242
Query: 467 VQRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF 526
+ +GF A + + G ++ +S +Y ++Y + C W I P + VK+ F
Sbjct: 243 IGGRGFKAYYFS--GECQEVYMAMRGNFSSPQY-PSSYPNNIRCHWTIRLPPGYQVKVFF 299
Query: 527 LTFELEREAN----CRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDD 582
L +LE + C +D++ F +CG +PP + S+ LL+ TD
Sbjct: 300 LDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDR 359
Query: 583 SLVFKGFSASY 593
S +GFS +Y
Sbjct: 360 STTRRGFSVAY 370
Score = 107 bits (256), Expect = 2e-22
Identities = 51/155 (32%), Positives = 86/155 (55%), Gaps = 5/155 (3%)
Query: 11 CGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDD 70
CGS + P + S G L VV++ + RGF+A+Y + ++ + G+ SP YP
Sbjct: 218 CGSTRPPTLVSLGHELQVVFKSDFNIGG-RGFKAYYFSGECQEVYMAMRGNFSSPQYPSS 276
Query: 71 YQPNKLCIWKLSVPQDYQVALRFHSFEVENHD----TCSYDKVKVRDGDSMDSPLIGMFC 126
Y N C W + +P YQV + F ++E + TC +D + DG S ++PL+G +C
Sbjct: 277 YPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWC 336
Query: 127 GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
GH +PP + S+ N+LL++ +D + + GFS ++
Sbjct: 337 GHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYI 371
Score = 97.5 bits (232), Expect = 1e-19
Identities = 56/145 (38%), Positives = 78/145 (53%), Gaps = 10/145 (6%)
Query: 32 PGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVAL 91
PGL+ + G + CGG + S G+ SPN+P Y N C W + V + V L
Sbjct: 18 PGLQAQAMEGVK------CGGVLSAPS-GNFSSPNFPRLYPYNTECSWLIVVAEGSSVLL 70
Query: 92 RFHSFEVENHDTCSYDKVKVRDGDSMD-SPLIGMFCGHKIPPDIRSTSNKLLVIFESDST 150
FH+F++E HDTCS+D +++ +G S D L+G FCG PP S+ + + VIF SD
Sbjct: 71 TFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKH 130
Query: 151 VQKAGFSATFMKEFDECASIDHGCS 175
V GFSA + K D C + G S
Sbjct: 131 VASHGFSAGYQK--DVCGGVLTGLS 153
Score = 90.2 bits (214), Expect = 2e-17
Identities = 48/119 (40%), Positives = 59/119 (49%), Gaps = 4/119 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L P+G +SP+FP LYP C W IV + L F FDLE Y C +
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLE----YHDTCSF 85
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDV 324
D + +++ D G FCG PPP TS V+ V F SD V GF+A Y DV
Sbjct: 86 DFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKDV 144
Score = 87.0 bits (206), Expect = 2e-16
Identities = 55/167 (32%), Positives = 82/167 (49%), Gaps = 9/167 (5%)
Query: 6 VLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEA-VCGGDIEVDSNGHLES 64
+LGR CG P S+ ++V++ + H GF A Y+ VCGG + +G L S
Sbjct: 101 LLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASH-GFSAGYQKDVCGG-VLTGLSGVLTS 158
Query: 65 PNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIG- 123
P YP++Y + C W + V L F F+VE ++ C+YD V V G P G
Sbjct: 159 PEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGG---PGPTRGH 215
Query: 124 MFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASI 170
+CG PP + S ++L V+F+SD + GF A + EC +
Sbjct: 216 HYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFS--GECQEV 260
Score = 83.0 bits (196), Expect = 3e-15
Identities = 49/127 (38%), Positives = 64/127 (50%), Gaps = 9/127 (7%)
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
++ CGG L G +G +TSP +P YP C W I A + L F F +EGN +E
Sbjct: 142 KDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGN----EE 197
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD V V LG R +CG+ PP + S G L+V F SD ++ GF A Y+
Sbjct: 198 CTYDYVAV---LGGPGPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYF- 253
Query: 323 DVDECAE 329
EC E
Sbjct: 254 -SGECQE 259
Score = 67.3 bits (157), Expect = 2e-10
Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 1/115 (0%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
C G +SP +P YP C W I PP +++ + F DLE + + C++
Sbjct: 257 CQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDF 316
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + ++ G +CG LPPPVTS + L + +D S R GF+ Y
Sbjct: 317 DHLAAFDG-ASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 58.4 bits (135), Expect = 7e-08
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 5/122 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A CGG LSA +S + Y +C W I V LTF F+LE
Sbjct: 24 AMEGVKCGGVLSAPSGN---FSSPNF-PRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEY 79
Query: 534 EANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSAS 592
C +D+++++ FCG PP S+ + V F +D + GFSA
Sbjct: 80 HDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAG 139
Query: 593 YQ 594
YQ
Sbjct: 140 YQ 141
>CR536570-1|CAG38807.1| 415|Homo sapiens PCOLCE2 protein.
Length = 415
Score = 128 bits (310), Expect = 5e-29
Identities = 77/237 (32%), Positives = 111/237 (46%), Gaps = 14/237 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T G I S +P YP C W+ + G + L F +LE C YD V
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA------- 479
+Y+G A+ + +G FCG+ P +++S N+M + SD + GF+A S A
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L + + + D Y + C W+I AP+N ++L F F++ER+ C
Sbjct: 152 QYCGGLL---DRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
RYDYV VF +CG P IVS LL++F +D SL GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 114 bits (275), Expect = 8e-25
Identities = 83/269 (30%), Positives = 120/269 (44%), Gaps = 40/269 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G +G I S FP +YPP C W+I P + LNF DLE +++ C Y
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL----CRY 88
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V V++ G +R G FCGT P + S G+ + VQ SD + +GF A++
Sbjct: 89 DFVDVYN--GHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF----- 141
Query: 326 ECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPA 385
AE N C L SG PN D +YPA
Sbjct: 142 SAAEPNERGDQYCGGLLDR-----PSGSFKTPNWPD-------------------RDYPA 177
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKTLGIFCGS 444
CVW I+L F F++E C YD+V +++G D + +G +CG
Sbjct: 178 GV----TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD 233
Query: 445 KLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
P +++ +N++ + F SD S+ GF+
Sbjct: 234 SPPAPIVSERNELLIQFLSDLSLTADGFI 262
Score = 85.0 bits (201), Expect = 7e-16
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---------CGGDIEVD 57
+GR CG+ + + S+G+++ V + GF A + A CGG ++
Sbjct: 103 IGRFCGTFRPGALVSSGNKMMVQMISDANTAGN-GFMAMFSAAEPNERGDQYCGGLLDRP 161
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS 116
S G ++PN+PD DY C+W + P++ + L+F F+VE + C YD V V +G
Sbjct: 162 S-GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGE 220
Query: 117 M-DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+ D+ IG +CG P I S N+LL+ F SD ++ GF
Sbjct: 221 VNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 82.6 bits (195), Expect = 4e-15
Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L P+G+ +P++P+ YP C+W IVAP I L F FD+E ++ C
Sbjct: 154 CGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNY----CR 209
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD V V + + RR G +CG + P P+ S+ + L +QF SD S+ GF Y
Sbjct: 210 YDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + +S G + S +P Y PN C WK++VP+ V L F ++E+ + C YD V
Sbjct: 33 CGGILTGES-GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V +G + + IG FCG P + S+ NK++V SD+ GF A F
Sbjct: 92 DVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF 141
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 5/119 (4%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L T E + S G Y + C W I P V L F +LE + CRY
Sbjct: 33 CGGIL--TGESGFIGSEGFPG--VYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRY 88
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
D+V V+ FCG P +VS+ ++V+ +D + GF A + +P
Sbjct: 89 DFVDVYNGHANGQRIGR-FCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146
>AY358557-1|AAQ88921.1| 415|Homo sapiens PCOLCE2 protein.
Length = 415
Score = 128 bits (310), Expect = 5e-29
Identities = 77/237 (32%), Positives = 111/237 (46%), Gaps = 14/237 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T G I S +P YP C W+ + G + L F +LE C YD V
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA------- 479
+Y+G A+ + +G FCG+ P +++S N+M + SD + GF+A S A
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L + + + D Y + C W+I AP+N ++L F F++ER+ C
Sbjct: 152 QYCGGLL---DRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
RYDYV VF +CG P IVS LL++F +D SL GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 114 bits (275), Expect = 8e-25
Identities = 83/269 (30%), Positives = 120/269 (44%), Gaps = 40/269 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G +G I S FP +YPP C W+I P + LNF DLE +++ C Y
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL----CRY 88
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V V++ G +R G FCGT P + S G+ + VQ SD + +GF A++
Sbjct: 89 DFVDVYN--GHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF----- 141
Query: 326 ECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPA 385
AE N C L SG PN D +YPA
Sbjct: 142 SAAEPNERGDQYCGGLLDR-----PSGSFKTPNWPD-------------------RDYPA 177
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKTLGIFCGS 444
CVW I+L F F++E C YD+V +++G D + +G +CG
Sbjct: 178 GV----TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD 233
Query: 445 KLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
P +++ +N++ + F SD S+ GF+
Sbjct: 234 SPPAPIVSERNELLIQFLSDLSLTADGFI 262
Score = 85.0 bits (201), Expect = 7e-16
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---------CGGDIEVD 57
+GR CG+ + + S+G+++ V + GF A + A CGG ++
Sbjct: 103 IGRFCGTFRPGALVSSGNKMMVQMISDANTAGN-GFMAMFSAAEPNERGDQYCGGLLDRP 161
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS 116
S G ++PN+PD DY C+W + P++ + L+F F+VE + C YD V V +G
Sbjct: 162 S-GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGE 220
Query: 117 M-DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+ D+ IG +CG P I S N+LL+ F SD ++ GF
Sbjct: 221 VNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 82.6 bits (195), Expect = 4e-15
Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L P+G+ +P++P+ YP C+W IVAP I L F FD+E ++ C
Sbjct: 154 CGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNY----CR 209
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD V V + + RR G +CG + P P+ S+ + L +QF SD S+ GF Y
Sbjct: 210 YDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + +S G + S +P Y PN C WK++VP+ V L F ++E+ + C YD V
Sbjct: 33 CGGILTGES-GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V +G + + IG FCG P + S+ NK++V SD+ GF A F
Sbjct: 92 DVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF 141
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 5/119 (4%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L T E + S G Y + C W I P V L F +LE + CRY
Sbjct: 33 CGGIL--TGESGFIGSEGFPG--VYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRY 88
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
D+V V+ FCG P +VS+ ++V+ +D + GF A + +P
Sbjct: 89 DFVDVYNGHANGQRIGR-FCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146
>AY035400-1|AAK63128.1| 415|Homo sapiens procollagen C-proteinase
enhancer protein 2 protein.
Length = 415
Score = 128 bits (310), Expect = 5e-29
Identities = 77/237 (32%), Positives = 111/237 (46%), Gaps = 14/237 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T G I S +P YP C W+ + G + L F +LE C YD V
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA------- 479
+Y+G A+ + +G FCG+ P +++S N+M + SD + GF+A S A
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L + + + D Y + C W+I AP+N ++L F F++ER+ C
Sbjct: 152 QYCGGLL---DRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
RYDYV VF +CG P IVS LL++F +D SL GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 114 bits (275), Expect = 8e-25
Identities = 83/269 (30%), Positives = 120/269 (44%), Gaps = 40/269 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G +G I S FP +YPP C W+I P + LNF DLE +++ C Y
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL----CRY 88
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V V++ G +R G FCGT P + S G+ + VQ SD + +GF A++
Sbjct: 89 DFVDVYN--GHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF----- 141
Query: 326 ECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPA 385
AE N C L SG PN D +YPA
Sbjct: 142 SAAEPNERGDQYCGGLLDR-----PSGSFKTPNWPD-------------------RDYPA 177
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKTLGIFCGS 444
CVW I+L F F++E C YD+V +++G D + +G +CG
Sbjct: 178 GV----TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD 233
Query: 445 KLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
P +++ +N++ + F SD S+ GF+
Sbjct: 234 SPPAPIVSERNELLIQFLSDLSLTADGFI 262
Score = 85.0 bits (201), Expect = 7e-16
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---------CGGDIEVD 57
+GR CG+ + + S+G+++ V + GF A + A CGG ++
Sbjct: 103 IGRFCGTFRPGALVSSGNKMMVQMISDANTAGN-GFMAMFSAAEPNERGDQYCGGLLDRP 161
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS 116
S G ++PN+PD DY C+W + P++ + L+F F+VE + C YD V V +G
Sbjct: 162 S-GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGE 220
Query: 117 M-DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+ D+ IG +CG P I S N+LL+ F SD ++ GF
Sbjct: 221 VNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 82.6 bits (195), Expect = 4e-15
Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L P+G+ +P++P+ YP C+W IVAP I L F FD+E ++ C
Sbjct: 154 CGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNY----CR 209
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD V V + + RR G +CG + P P+ S+ + L +QF SD S+ GF Y
Sbjct: 210 YDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + +S G + S +P Y PN C WK++VP+ V L F ++E+ + C YD V
Sbjct: 33 CGGILTGES-GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V +G + + IG FCG P + S+ NK++V SD+ GF A F
Sbjct: 92 DVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF 141
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 5/119 (4%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L T E + S G Y + C W I P V L F +LE + CRY
Sbjct: 33 CGGIL--TGESGFIGSEGFPG--VYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRY 88
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
D+V V+ FCG P +VS+ ++V+ +D + GF A + +P
Sbjct: 89 DFVDVYNGHANGQRIGR-FCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146
>AF098269-1|AAF04621.1| 415|Homo sapiens procollagen C-terminal
proteinase enhancer protein 2 protein.
Length = 415
Score = 128 bits (310), Expect = 5e-29
Identities = 77/237 (32%), Positives = 111/237 (46%), Gaps = 14/237 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T G I S +P YP C W+ + G + L F +LE C YD V
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA------- 479
+Y+G A+ + +G FCG+ P +++S N+M + SD + GF+A S A
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L + + + D Y + C W+I AP+N ++L F F++ER+ C
Sbjct: 152 QYCGGLL---DRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
RYDYV VF +CG P IVS LL++F +D SL GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 114 bits (275), Expect = 8e-25
Identities = 83/269 (30%), Positives = 120/269 (44%), Gaps = 40/269 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G +G I S FP +YPP C W+I P + LNF DLE +++ C Y
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL----CRY 88
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V V++ G +R G FCGT P + S G+ + VQ SD + +GF A++
Sbjct: 89 DFVDVYN--GHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF----- 141
Query: 326 ECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPA 385
AE N C L SG PN D +YPA
Sbjct: 142 SAAEPNERGDQYCGGLLDR-----PSGSFKTPNWPD-------------------RDYPA 177
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKTLGIFCGS 444
CVW I+L F F++E C YD+V +++G D + +G +CG
Sbjct: 178 GV----TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD 233
Query: 445 KLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
P +++ +N++ + F SD S+ GF+
Sbjct: 234 SPPAPIVSERNELLIQFLSDLSLTADGFI 262
Score = 85.0 bits (201), Expect = 7e-16
Identities = 52/161 (32%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---------CGGDIEVD 57
+GR CG+ + + S+G+++ V + GF A + A CGG ++
Sbjct: 103 IGRFCGTFRPGALVSSGNKMMVQMISDANTAGN-GFMAMFSAAEPNERGDQYCGGLLDRP 161
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS 116
S G ++PN+PD DY C+W + P++ + L+F F+VE + C YD V V +G
Sbjct: 162 S-GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGE 220
Query: 117 M-DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+ D+ IG +CG P I S N+LL+ F SD ++ GF
Sbjct: 221 VNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 82.6 bits (195), Expect = 4e-15
Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L P+G+ +P++P+ YP C+W IVAP I L F FD+E ++ C
Sbjct: 154 CGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNY----CR 209
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD V V + + RR G +CG + P P+ S+ + L +QF SD S+ GF Y
Sbjct: 210 YDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + +S G + S +P Y PN C WK++VP+ V L F ++E+ + C YD V
Sbjct: 33 CGGILTGES-GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V +G + + IG FCG P + S+ NK++V SD+ GF A F
Sbjct: 92 DVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMF 141
Score = 57.6 bits (133), Expect = 1e-07
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 5/119 (4%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L T E + S G Y + C W I P V L F +LE + CRY
Sbjct: 33 CGGIL--TGESGFIGSEGFPG--VYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRY 88
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
D+V V+ FCG P +VS+ ++V+ +D + GF A + +P
Sbjct: 89 DFVDVYNGHANGQRIGR-FCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAEP 146
>AK223633-1|BAD97353.1| 415|Homo sapiens procollagen
C-endopeptidase enhancer 2 variant protein.
Length = 415
Score = 128 bits (309), Expect = 6e-29
Identities = 77/237 (32%), Positives = 110/237 (46%), Gaps = 14/237 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C +T G I S +P YP C W+ + G + L F +LE C YD V
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVD 92
Query: 427 IYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA------- 479
+Y+G A+ + +G FCG+ P +++S N M + SD + GF+A S A
Sbjct: 93 VYNG-HANGQRIGRFCGTFRPGALVSSGNNMMVQMISDANTAGNGFMAMFSAAEPNERGD 151
Query: 480 --CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
CGG L + + + D Y + C W+I AP+N ++L F F++ER+ C
Sbjct: 152 QYCGGLL---DRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYC 208
Query: 538 RYDYVQVF-XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
RYDYV VF +CG P IVS LL++F +D SL GF Y
Sbjct: 209 RYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 114 bits (274), Expect = 1e-24
Identities = 83/269 (30%), Positives = 120/269 (44%), Gaps = 40/269 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G +G I S FP +YPP C W+I P + LNF DLE +++ C Y
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL----CRY 88
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V V++ G +R G FCGT P + S G+ + VQ SD + +GF A++
Sbjct: 89 DFVDVYN--GHANGQRIGRFCGTFRPGALVSSGNNMMVQMISDANTAGNGFMAMF----- 141
Query: 326 ECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPA 385
AE N C L SG PN D +YPA
Sbjct: 142 SAAEPNERGDQYCGGLLDR-----PSGSFKTPNWPD-------------------RDYPA 177
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKTLGIFCGS 444
CVW I+L F F++E C YD+V +++G D + +G +CG
Sbjct: 178 GV----TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD 233
Query: 445 KLPHLVMASQNQMYMVFKSDGSVQRKGFL 473
P +++ +N++ + F SD S+ GF+
Sbjct: 234 SPPAPIVSERNELLIQFLSDLSLTADGFI 262
Score = 84.2 bits (199), Expect = 1e-15
Identities = 52/161 (32%), Positives = 82/161 (50%), Gaps = 13/161 (8%)
Query: 7 LGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV---------CGGDIEVD 57
+GR CG+ + + S+G+ + V + GF A + A CGG ++
Sbjct: 103 IGRFCGTFRPGALVSSGNNMMVQMISDANTAGN-GFMAMFSAAEPNERGDQYCGGLLDRP 161
Query: 58 SNGHLESPNYPD-DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS 116
S G ++PN+PD DY C+W + P++ + L+F F+VE + C YD V V +G
Sbjct: 162 S-GSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGE 220
Query: 117 M-DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF 156
+ D+ IG +CG P I S N+LL+ F SD ++ GF
Sbjct: 221 VNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF 261
Score = 82.6 bits (195), Expect = 4e-15
Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 5/116 (4%)
Query: 206 CGGALYGPNGTITSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
CGG L P+G+ +P++P+ YP C+W IVAP I L F FD+E ++ C
Sbjct: 154 CGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLIELKFEKFDVERDNY----CR 209
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD V V + + RR G +CG + P P+ S+ + L +QF SD S+ GF Y
Sbjct: 210 YDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGFIGHY 265
Score = 75.4 bits (177), Expect = 6e-13
Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + +S G + S +P Y PN C WK++VP+ V L F ++E+ + C YD V
Sbjct: 33 CGGILTGES-GFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFV 91
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V +G + + IG FCG P + S+ N ++V SD+ GF A F
Sbjct: 92 DVYNGHA-NGQRIGRFCGTFRPGALVSSGNNMMVQMISDANTAGNGFMAMF 141
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 5/119 (4%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L T E + S G Y + C W I P V L F +LE + CRY
Sbjct: 33 CGGIL--TGESGFIGSEGFPG--VYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRY 88
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKP 598
D+V V+ FCG P +VS+ ++V+ +D + GF A + +P
Sbjct: 89 DFVDVYNGHANGQRIGR-FCGTFRPGALVSSGNNMMVQMISDANTAGNGFMAMFSAAEP 146
>X06596-1|CAA29817.1| 688|Homo sapiens complement protein C1s
precursor protein.
Length = 688
Score = 127 bits (307), Expect = 1e-28
Identities = 87/285 (30%), Positives = 138/285 (48%), Gaps = 20/285 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SPNYP Y W + VP+ Y + L F ++E + C+YD V++ GD+ +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 120 PLIGMFCGHK----IPPDIRSTSNKLLVIFESDSTVQK--AGFSATFM-KEFDECAS-ID 171
L G + I + + NKL VIF+SD + ++ GF+A ++ + +EC +D
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
Query: 172 HGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALY-GPNGTITSPSFPELYPPLK 230
CSH C N +GGY C+C Y LH D K C C G ++ G I SP++P+ YP
Sbjct: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
Query: 231 NCLWEIVAPP--QHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGT 288
C ++I Q +TL FD+E C DS+ + D R+ G +CG
Sbjct: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADS-AGNC-LDSLVF---VAGD--RQFGPYCGH 253
Query: 289 ALPPP--VTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENN 331
P P + + + L + F +D + + G+ Y+ D C + +
Sbjct: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
Score = 107 bits (256), Expect = 2e-22
Identities = 82/273 (30%), Positives = 126/273 (46%), Gaps = 25/273 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP++P+ YP W+I P + I L FTH D+E + C YDSV + +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE----LSENCAYDSVQI---I 73
Query: 275 GADVLRRHGAFCG--TALPP--PVTSDGSV----LRVQFTSDGSVHR--SGFAAVYYI-D 323
D G CG ++ P P+ + V L+V F SD S +GFAA Y D
Sbjct: 74 SGDT--EEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATD 131
Query: 324 VDECAEN-NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDV-TLPHGTIFSP 381
++EC + + C H C+N +GGY C+C + LH + +C C DV T G I SP
Sbjct: 132 INECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGV-NCSGDVFTALIGEIASP 190
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
NYP YP C +Q G ++ + + + + + A + G +
Sbjct: 191 NYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPY 250
Query: 442 CGSKLPH--LVMASQNQMYMVFKSDGSVQRKGF 472
CG P + N + ++F++D + Q+KG+
Sbjct: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGW 283
Score = 63.3 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ--VALRFHSFEVENHDTCS-- 105
C GD+ G + SPNYP Y N C +++ + + +Q V LR F+VE D+
Sbjct: 175 CSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC 234
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPP--DIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D + GD G +CGH P +I + SN L +IF++D T QK G+ + +
Sbjct: 235 LDSLVFVAGDRQ----FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGD 290
Query: 164 FDECASID 171
C D
Sbjct: 291 PMPCPKED 298
Score = 61.3 bits (142), Expect = 1e-08
Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+G I SPNYP AYP+ + W G+ I L F ++E + CAYD V I G + +
Sbjct: 20 YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
Query: 435 VKTLGIFCGSKLPHLVMASQ-----NQMYMVFKSDGSVQRK--GFLA 474
+ G S PH + + N++ ++FKSD S + + GF A
Sbjct: 80 GRLCG-QRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAA 125
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
AY S + W+IE P + + L F ++E NC YD VQ+
Sbjct: 31 AYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQI 72
>M18767-1|AAA51853.1| 688|Homo sapiens C1S protein.
Length = 688
Score = 127 bits (307), Expect = 1e-28
Identities = 87/285 (30%), Positives = 138/285 (48%), Gaps = 20/285 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SPNYP Y W + VP+ Y + L F ++E + C+YD V++ GD+ +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 120 PLIGMFCGHK----IPPDIRSTSNKLLVIFESDSTVQK--AGFSATFM-KEFDECAS-ID 171
L G + I + + NKL VIF+SD + ++ GF+A ++ + +EC +D
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
Query: 172 HGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALY-GPNGTITSPSFPELYPPLK 230
CSH C N +GGY C+C Y LH D K C C G ++ G I SP++P+ YP
Sbjct: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
Query: 231 NCLWEIVAPP--QHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGT 288
C ++I Q +TL FD+E C DS+ + D R+ G +CG
Sbjct: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADS-AGNC-LDSLVF---VAGD--RQFGPYCGH 253
Query: 289 ALPPP--VTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENN 331
P P + + + L + F +D + + G+ Y+ D C + +
Sbjct: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
Score = 107 bits (256), Expect = 2e-22
Identities = 82/273 (30%), Positives = 126/273 (46%), Gaps = 25/273 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP++P+ YP W+I P + I L FTH D+E + C YDSV + +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE----LSENCAYDSVQI---I 73
Query: 275 GADVLRRHGAFCG--TALPP--PVTSDGSV----LRVQFTSDGSVHR--SGFAAVYYI-D 323
D G CG ++ P P+ + V L+V F SD S +GFAA Y D
Sbjct: 74 SGDT--EEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATD 131
Query: 324 VDECAEN-NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDV-TLPHGTIFSP 381
++EC + + C H C+N +GGY C+C + LH + +C C DV T G I SP
Sbjct: 132 INECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGV-NCSGDVFTALIGEIASP 190
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
NYP YP C +Q G ++ + + + + + A + G +
Sbjct: 191 NYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPY 250
Query: 442 CGSKLPH--LVMASQNQMYMVFKSDGSVQRKGF 472
CG P + N + ++F++D + Q+KG+
Sbjct: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGW 283
Score = 63.3 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ--VALRFHSFEVENHDTCS-- 105
C GD+ G + SPNYP Y N C +++ + + +Q V LR F+VE D+
Sbjct: 175 CSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC 234
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPP--DIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D + GD G +CGH P +I + SN L +IF++D T QK G+ + +
Sbjct: 235 LDSLVFVAGDRQ----FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGD 290
Query: 164 FDECASID 171
C D
Sbjct: 291 PMPCPKED 298
Score = 61.3 bits (142), Expect = 1e-08
Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+G I SPNYP AYP+ + W G+ I L F ++E + CAYD V I G + +
Sbjct: 20 YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
Query: 435 VKTLGIFCGSKLPHLVMASQ-----NQMYMVFKSDGSVQRK--GFLA 474
+ G S PH + + N++ ++FKSD S + + GF A
Sbjct: 80 GRLCG-QRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAA 125
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
AY S + W+IE P + + L F ++E NC YD VQ+
Sbjct: 31 AYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQI 72
>J04080-1|AAA51852.1| 688|Homo sapiens C1S protein.
Length = 688
Score = 127 bits (307), Expect = 1e-28
Identities = 87/285 (30%), Positives = 138/285 (48%), Gaps = 20/285 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SPNYP Y W + VP+ Y + L F ++E + C+YD V++ GD+ +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 120 PLIGMFCGHK----IPPDIRSTSNKLLVIFESDSTVQK--AGFSATFM-KEFDECAS-ID 171
L G + I + + NKL VIF+SD + ++ GF+A ++ + +EC +D
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
Query: 172 HGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALY-GPNGTITSPSFPELYPPLK 230
CSH C N +GGY C+C Y LH D K C C G ++ G I SP++P+ YP
Sbjct: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
Query: 231 NCLWEIVAPP--QHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGT 288
C ++I Q +TL FD+E C DS+ + D R+ G +CG
Sbjct: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADS-AGNC-LDSLVF---VAGD--RQFGPYCGH 253
Query: 289 ALPPP--VTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENN 331
P P + + + L + F +D + + G+ Y+ D C + +
Sbjct: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
Score = 107 bits (256), Expect = 2e-22
Identities = 82/273 (30%), Positives = 126/273 (46%), Gaps = 25/273 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP++P+ YP W+I P + I L FTH D+E + C YDSV + +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE----LSENCAYDSVQI---I 73
Query: 275 GADVLRRHGAFCG--TALPP--PVTSDGSV----LRVQFTSDGSVHR--SGFAAVYYI-D 323
D G CG ++ P P+ + V L+V F SD S +GFAA Y D
Sbjct: 74 SGDT--EEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATD 131
Query: 324 VDECAEN-NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDV-TLPHGTIFSP 381
++EC + + C H C+N +GGY C+C + LH + +C C DV T G I SP
Sbjct: 132 INECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGV-NCSGDVFTALIGEIASP 190
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
NYP YP C +Q G ++ + + + + + A + G +
Sbjct: 191 NYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPY 250
Query: 442 CGSKLPH--LVMASQNQMYMVFKSDGSVQRKGF 472
CG P + N + ++F++D + Q+KG+
Sbjct: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGW 283
Score = 63.3 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ--VALRFHSFEVENHDTCS-- 105
C GD+ G + SPNYP Y N C +++ + + +Q V LR F+VE D+
Sbjct: 175 CSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC 234
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPP--DIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D + GD G +CGH P +I + SN L +IF++D T QK G+ + +
Sbjct: 235 LDSLVFVAGDRQ----FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGD 290
Query: 164 FDECASID 171
C D
Sbjct: 291 PMPCPKED 298
Score = 61.3 bits (142), Expect = 1e-08
Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+G I SPNYP AYP+ + W G+ I L F ++E + CAYD V I G + +
Sbjct: 20 YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
Query: 435 VKTLGIFCGSKLPHLVMASQ-----NQMYMVFKSDGSVQRK--GFLA 474
+ G S PH + + N++ ++FKSD S + + GF A
Sbjct: 80 GRLCG-QRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAA 125
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
AY S + W+IE P + + L F ++E NC YD VQ+
Sbjct: 31 AYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQI 72
>BC056903-1|AAH56903.1| 688|Homo sapiens complement component 1, s
subcomponent protein.
Length = 688
Score = 127 bits (307), Expect = 1e-28
Identities = 87/285 (30%), Positives = 138/285 (48%), Gaps = 20/285 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SPNYP Y W + VP+ Y + L F ++E + C+YD V++ GD+ +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 120 PLIGMFCGHK----IPPDIRSTSNKLLVIFESDSTVQK--AGFSATFM-KEFDECAS-ID 171
L G + I + + NKL VIF+SD + ++ GF+A ++ + +EC +D
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
Query: 172 HGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALY-GPNGTITSPSFPELYPPLK 230
CSH C N +GGY C+C Y LH D K C C G ++ G I SP++P+ YP
Sbjct: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
Query: 231 NCLWEIVAPP--QHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGT 288
C ++I Q +TL FD+E C DS+ + D R+ G +CG
Sbjct: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADS-AGNC-LDSLVF---VAGD--RQFGPYCGH 253
Query: 289 ALPPP--VTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENN 331
P P + + + L + F +D + + G+ Y+ D C + +
Sbjct: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
Score = 107 bits (256), Expect = 2e-22
Identities = 82/273 (30%), Positives = 126/273 (46%), Gaps = 25/273 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP++P+ YP W+I P + I L FTH D+E + C YDSV + +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE----LSENCAYDSVQI---I 73
Query: 275 GADVLRRHGAFCG--TALPP--PVTSDGSV----LRVQFTSDGSVHR--SGFAAVYYI-D 323
D G CG ++ P P+ + V L+V F SD S +GFAA Y D
Sbjct: 74 SGDT--EEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATD 131
Query: 324 VDECAEN-NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDV-TLPHGTIFSP 381
++EC + + C H C+N +GGY C+C + LH + +C C DV T G I SP
Sbjct: 132 INECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGV-NCSGDVFTALIGEIASP 190
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
NYP YP C +Q G ++ + + + + + A + G +
Sbjct: 191 NYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPY 250
Query: 442 CGSKLPH--LVMASQNQMYMVFKSDGSVQRKGF 472
CG P + N + ++F++D + Q+KG+
Sbjct: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGW 283
Score = 63.3 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ--VALRFHSFEVENHDTCS-- 105
C GD+ G + SPNYP Y N C +++ + + +Q V LR F+VE D+
Sbjct: 175 CSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC 234
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPP--DIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D + GD G +CGH P +I + SN L +IF++D T QK G+ + +
Sbjct: 235 LDSLVFVAGDRQ----FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGD 290
Query: 164 FDECASID 171
C D
Sbjct: 291 PMPCPKED 298
Score = 61.3 bits (142), Expect = 1e-08
Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+G I SPNYP AYP+ + W G+ I L F ++E + CAYD V I G + +
Sbjct: 20 YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
Query: 435 VKTLGIFCGSKLPHLVMASQ-----NQMYMVFKSDGSVQRK--GFLA 474
+ G S PH + + N++ ++FKSD S + + GF A
Sbjct: 80 GRLCG-QRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAA 125
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
AY S + W+IE P + + L F ++E NC YD VQ+
Sbjct: 31 AYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQI 72
>AB009076-1|BAA86864.1| 329|Homo sapiens complement C1s protein.
Length = 329
Score = 127 bits (307), Expect = 1e-28
Identities = 87/285 (30%), Positives = 138/285 (48%), Gaps = 20/285 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G + SPNYP Y W + VP+ Y + L F ++E + C+YD V++ GD+ +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 120 PLIGMFCGHK----IPPDIRSTSNKLLVIFESDSTVQK--AGFSATFM-KEFDECAS-ID 171
L G + I + + NKL VIF+SD + ++ GF+A ++ + +EC +D
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
Query: 172 HGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALY-GPNGTITSPSFPELYPPLK 230
CSH C N +GGY C+C Y LH D K C C G ++ G I SP++P+ YP
Sbjct: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
Query: 231 NCLWEIVAPP--QHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGT 288
C ++I Q +TL FD+E C DS+ + D R+ G +CG
Sbjct: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADS-AGNC-LDSLVF---VAGD--RQFGPYCGH 253
Query: 289 ALPPP--VTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENN 331
P P + + + L + F +D + + G+ Y+ D C + +
Sbjct: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
Score = 107 bits (256), Expect = 2e-22
Identities = 82/273 (30%), Positives = 126/273 (46%), Gaps = 25/273 (9%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G I SP++P+ YP W+I P + I L FTH D+E + C YDSV + +
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE----LSENCAYDSVQI---I 73
Query: 275 GADVLRRHGAFCG--TALPP--PVTSDGSV----LRVQFTSDGSVHR--SGFAAVYYI-D 323
D G CG ++ P P+ + V L+V F SD S +GFAA Y D
Sbjct: 74 SGDT--EEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATD 131
Query: 324 VDECAEN-NGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDV-TLPHGTIFSP 381
++EC + + C H C+N +GGY C+C + LH + +C C DV T G I SP
Sbjct: 132 INECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGV-NCSGDVFTALIGEIASP 190
Query: 382 NYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIF 441
NYP YP C +Q G ++ + + + + + A + G +
Sbjct: 191 NYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPY 250
Query: 442 CGSKLPH--LVMASQNQMYMVFKSDGSVQRKGF 472
CG P + N + ++F++D + Q+KG+
Sbjct: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGW 283
Score = 63.3 bits (147), Expect = 3e-09
Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 10/128 (7%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ--VALRFHSFEVENHDTCS-- 105
C GD+ G + SPNYP Y N C +++ + + +Q V LR F+VE D+
Sbjct: 175 CSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC 234
Query: 106 YDKVKVRDGDSMDSPLIGMFCGHKIPP--DIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
D + GD G +CGH P +I + SN L +IF++D T QK G+ + +
Sbjct: 235 LDSLVFVAGDRQ----FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGD 290
Query: 164 FDECASID 171
C D
Sbjct: 291 PMPCPKED 298
Score = 61.3 bits (142), Expect = 1e-08
Identities = 36/107 (33%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+G I SPNYP AYP+ + W G+ I L F ++E + CAYD V I G + +
Sbjct: 20 YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
Query: 435 VKTLGIFCGSKLPHLVMASQ-----NQMYMVFKSDGSVQRK--GFLA 474
+ G S PH + + N++ ++FKSD S + + GF A
Sbjct: 80 GRLCG-QRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAA 125
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
AY S + W+IE P + + L F ++E NC YD VQ+
Sbjct: 31 AYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQI 72
>M14058-1|AAA51851.1| 705|Homo sapiens C1R protein.
Length = 705
Score = 125 bits (301), Expect = 6e-28
Identities = 91/307 (29%), Positives = 139/307 (45%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIFESDSTVQK------- 153
VK+ S D +G FCG P + S NK+L+ F +D + ++
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDHG--------CSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ G ++ G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-GKNI----GEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 121 bits (291), Expect = 9e-27
Identities = 93/291 (31%), Positives = 135/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTSDGSVHRSG-------FAAV 319
AD + G FCG PP S G+ + + F +D S +G F A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNGG--------CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.5 bits (155), Expect = 3e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.5 bits (93), Expect = 0.009
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F TD S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAV 141
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
>X04701-1|CAA28407.1| 705|Homo sapiens protein ( Human mRNA for
complement component C1r. ).
Length = 705
Score = 124 bits (299), Expect = 1e-27
Identities = 91/307 (29%), Positives = 139/307 (45%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIFESDSTVQK------- 153
VK+ S D +G FCG P + S NK+L+ F +D + ++
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDH--------GCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ G ++ G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-GKNI----GEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 120 bits (289), Expect = 2e-26
Identities = 93/291 (31%), Positives = 135/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTSDGSVHRSG-------FAAV 319
AD + G FCG PP S G+ + + F +D S +G F A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNG--------GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.5 bits (155), Expect = 3e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.5 bits (93), Expect = 0.009
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F TD S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAV 141
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
>BC035220-1|AAH35220.1| 705|Homo sapiens complement component 1, r
subcomponent protein.
Length = 705
Score = 124 bits (299), Expect = 1e-27
Identities = 91/307 (29%), Positives = 139/307 (45%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIFESDSTVQK------- 153
VK+ S D +G FCG P + S NK+L+ F +D + ++
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDH--------GCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ G ++ G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-GKNI----GEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 120 bits (289), Expect = 2e-26
Identities = 93/291 (31%), Positives = 135/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTSDGSVHRSG-------FAAV 319
AD + G FCG PP S G+ + + F +D S +G F A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNG--------GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.5 bits (155), Expect = 3e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.5 bits (93), Expect = 0.009
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F TD S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAV 141
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
>AB083037-1|BAC19850.2| 705|Homo sapiens r subcomponent of
complement component 1 protein.
Length = 705
Score = 124 bits (299), Expect = 1e-27
Identities = 91/307 (29%), Positives = 139/307 (45%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIFESDSTVQK------- 153
VK+ S D +G FCG P + S NK+L+ F +D + ++
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDH--------GCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ G ++ G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-GKNI----GEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 120 bits (289), Expect = 2e-26
Identities = 93/291 (31%), Positives = 135/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTSDGSVHRSG-------FAAV 319
AD + G FCG PP S G+ + + F +D S +G F A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNG--------GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.5 bits (155), Expect = 3e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.5 bits (93), Expect = 0.009
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F TD S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAV 141
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
>AK222481-1|BAD96201.1| 705|Homo sapiens complement component 1, r
subcomponent variant protein.
Length = 705
Score = 124 bits (298), Expect = 1e-27
Identities = 92/307 (29%), Positives = 136/307 (44%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIF------ESDSTVQ-K 153
VK+ S D +G FCG P + S NK+L+ F E D T+
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEEDGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDH--------GCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ + G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-----RKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 120 bits (289), Expect = 2e-26
Identities = 93/291 (31%), Positives = 135/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTSDGS-------VHRSGFAAV 319
AD + G FCG PP S G+ + + F +D S + GF A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEEDGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNG--------GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANRKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.1 bits (154), Expect = 4e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANRKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.5 bits (93), Expect = 0.009
Identities = 33/98 (33%), Positives = 43/98 (43%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F TD S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTDFSNEEDGTIMFYKGFLAYYQAV 141
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANRKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
>AL355178-2|CAI23435.1| 426|Homo sapiens CUB and Sushi multiple
domains 2 protein.
Length = 426
Score = 122 bits (295), Expect = 3e-27
Identities = 107/389 (27%), Positives = 164/389 (42%), Gaps = 58/389 (14%)
Query: 121 LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF----MKEFDECASIDHGCSH 176
++G F G +P + STSN+L + F SD +V AGF + + E A +G
Sbjct: 1 MLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKT 60
Query: 177 S---CVNTLGGYECACDIGYELHSD--------------GKKCENACGGALYGPNGTITS 219
VN + ++C + H+ C CGG + G I S
Sbjct: 61 GERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILS 120
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA-DV 278
P FP YP +C W+I P + F +F E NH Y + + G +
Sbjct: 121 PGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDY----------IEIRNGPYET 170
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDECAE----NNGG 333
R G F G+ LP + S V F SD S +R GF Y ++ EC + NG
Sbjct: 171 SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGI 230
Query: 334 CQHECHNTLGGYECACHSGFTL--HP--------NKH------DCKEGGCKHDVTLPHGT 377
+ +N C G+ L HP N++ C E C ++T +GT
Sbjct: 231 VRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC-EVPCGGNITSSNGT 289
Query: 378 IFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKT 437
++SP +P+ Y + +DCVW + GH ++L ++ + EP + D +TI+DG
Sbjct: 290 VYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SGDFITIWDGPQQTAPR 345
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGS 466
LG+F S V +S NQ+ + F D +
Sbjct: 346 LGVFTRSMAKKTVQSSSNQVLLKFHRDAA 374
Score = 106 bits (254), Expect = 3e-22
Identities = 68/228 (29%), Positives = 107/228 (46%), Gaps = 26/228 (11%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG +E + G + SP +P +Y N C WK+++P + ++F +F E + +D
Sbjct: 105 AQCGGTVE-EMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HD 159
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+++R+G S ++G F G ++P + STS++ V F SD + + GF + E E
Sbjct: 160 YIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQAYELQE 219
Query: 167 CA-------SIDHGCSHS-----CVNTLGGYE------CACDIGYELHSDG--KKCENAC 206
C I G ++ L GY+ C G + D KCE C
Sbjct: 220 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPC 279
Query: 207 GGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
GG + NGT+ SP FP Y ++C+W I P H + LN + E
Sbjct: 280 GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 327
Score = 77.4 bits (182), Expect = 1e-13
Identities = 59/210 (28%), Positives = 91/210 (43%), Gaps = 24/210 (11%)
Query: 283 GAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY-IDVDECAE----NNGGCQHE 337
G+F GT +P + S + L + F SD SV +GF Y + + C E +NG E
Sbjct: 3 GSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGE 62
Query: 338 CHNTLGGYECACHSGFTLHPNKH-DCKEGG--------------CKHDVTLPHGTIFSPN 382
+ C G+ L + H C G C V G I SP
Sbjct: 63 RYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPG 122
Query: 383 YPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFC 442
+P YP+ DC W+ + G + F F EP+ +D++ I +G + +G F
Sbjct: 123 FPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----HDYIEIRNGPYETSRMMGRFS 178
Query: 443 GSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
GS+LP ++++ ++ + F SD S R GF
Sbjct: 179 GSELPSSLLSTSHETTVYFHSDHSQNRPGF 208
Score = 60.9 bits (141), Expect = 1e-08
Identities = 32/103 (31%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG+I SNG + SP +P Y ++ C+W ++VP + V L + E S
Sbjct: 276 EVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEP----SG 330
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
D + + DG +P +G+F ++S+SN++L+ F D+
Sbjct: 331 DFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDA 373
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 8/115 (6%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG EE++ + + N Y S DC W I P + FL F E +
Sbjct: 107 CGG---TVEEMEGVILSPGFPGN-YPSNMDCSWKIALPVGFGAHIQFLNFSTEPN----H 158
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
DY+++ F G ++P ++STS V F +D S GF YQ
Sbjct: 159 DYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQ 213
Score = 35.9 bits (79), Expect = 0.44
Identities = 17/41 (41%), Positives = 25/41 (60%)
Query: 438 LGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG F G+ +P L+ ++ NQ+Y+ F SD SV GF + T
Sbjct: 2 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 42
>AK222491-1|BAD96211.1| 705|Homo sapiens complement component 1, r
subcomponent variant protein.
Length = 705
Score = 122 bits (293), Expect = 5e-27
Identities = 91/307 (29%), Positives = 136/307 (44%), Gaps = 39/307 (12%)
Query: 51 GGDIEVDSN--GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
GG I + G + SP +P Y N ++VP Y+V L F F++E + C YD
Sbjct: 16 GGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDY 75
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPP--------DIRSTSNKLLVIF------ESDSTVQ-K 153
VK+ S D +G FCG P + S NK+L+ F E + T+
Sbjct: 76 VKI----SADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTGFSNEENGTIMFY 131
Query: 154 AGFSATFMK-EFDECASIDH--------GCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
GF A + + DECAS C H C N +GGY C+C GYEL D C+
Sbjct: 132 KGFLAYYQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQA 191
Query: 205 ACGGALY-GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHMYQQE 262
C LY +G I+S +P YPP C + I + L F FD++ + Q
Sbjct: 192 ECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQ--QVH 249
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
C YD + +++ + G FCG PP + + + + + F +D S G+ Y
Sbjct: 250 CPYDQLQIYAN-----RKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Query: 323 DVDECAE 329
++ +C +
Sbjct: 305 EIIKCPQ 311
Score = 118 bits (283), Expect = 8e-26
Identities = 92/291 (31%), Positives = 136/291 (46%), Gaps = 40/291 (13%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G +TSP FP+ YP I P +R+ L F FDLE + + C YD V K+
Sbjct: 27 GEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPS----EGCFYDYV----KI 78
Query: 275 GADVLRRHGAFCGT-----ALPP---PVTSDGSVLRVQFTS------DGSV-HRSGFAAV 319
AD + G FCG PP S G+ + + F + +G++ GF A
Sbjct: 79 SADK-KSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTGFSNEENGTIMFYKGFLAY 137
Query: 320 YY-IDVDECAENNG--------GCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
Y +D+DECA + CQH CHN +GGY C+C G+ L ++H C+
Sbjct: 138 YQAVDLDECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSEL 197
Query: 371 VTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTI 427
T G I S YP +YP C + G + L F F+++ HQ+ C YD + I
Sbjct: 198 YTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQI 257
Query: 428 YDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
Y A+ K +G FCG + P + S N + ++F +D S +G+ ++T
Sbjct: 258 Y----ANRKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTT 304
Score = 66.1 bits (154), Expect = 4e-10
Identities = 32/124 (25%), Positives = 67/124 (54%), Gaps = 7/124 (5%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDT-- 103
+A C ++ +++G++ S YP Y P+ C + + V + + L+F F++++H
Sbjct: 190 QAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVH 249
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C YD++++ + IG FCG + PPD+ ++SN + ++F +D + G+ + E
Sbjct: 250 CPYDQLQI----YANRKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTE 305
Query: 164 FDEC 167
+C
Sbjct: 306 IIKC 309
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/94 (26%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLT-FELE--REANCRYDYVQVFXXXXXXXXXXXTFC 559
+Y C+++I R + L FL F+++ ++ +C YD +Q++ FC
Sbjct: 213 SYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANRKNIGE----FC 268
Query: 560 GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G + PP++ ++S A+ + F TD+S +G+ Y
Sbjct: 269 GKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRY 302
Score = 38.7 bits (86), Expect = 0.063
Identities = 32/98 (32%), Positives = 42/98 (42%), Gaps = 19/98 (19%)
Query: 514 IEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG-----IKMPP--- 565
I P + VKL F F+LE C YDYV++ FCG + PP
Sbjct: 48 ITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCGQLGSPLGNPPGKK 103
Query: 566 EIVSTSEALLVRFRTDDS-------LVFKGFSASYQMV 596
E +S +L+ F T S + +KGF A YQ V
Sbjct: 104 EFMSQGNKMLLTFHTGFSNEENGTIMFYKGFLAYYQAV 141
>BT006995-1|AAP35641.1| 644|Homo sapiens neuropilin 1 protein.
Length = 644
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>BC007737-1|AAH07737.1| 609|Homo sapiens neuropilin 1 protein.
Length = 609
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>BC007533-1|AAH07533.1| 644|Homo sapiens neuropilin 1 protein.
Length = 644
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AY249243-1|AAP80144.1| 906|Homo sapiens neuropilin-1 protein.
Length = 906
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AF280547-1|AAG41406.1| 704|Homo sapiens neuropilin-1 soluble
isoform 11 protein.
Length = 704
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AF268691-1|AAQ14300.1| 641|Homo sapiens muscle type neuropilin 1
protein.
Length = 641
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AF145712-1|AAF44344.1| 644|Homo sapiens soluble neuropilin-1
protein.
Length = 644
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AF018956-1|AAC51759.1| 923|Homo sapiens neuropilin protein.
Length = 923
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDECGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AF016050-1|AAC12921.1| 923|Homo sapiens vascular endothelial cell
growth factor 165 receptor/neuropilin protein.
Length = 923
Score = 118 bits (283), Expect = 8e-26
Identities = 87/283 (30%), Positives = 126/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL353600-4|CAI17000.1| 704|Homo sapiens neuropilin 1 protein.
Length = 704
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL353600-3|CAI16999.1| 609|Homo sapiens neuropilin 1 protein.
Length = 609
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL353600-2|CAI16998.1| 644|Homo sapiens neuropilin 1 protein.
Length = 644
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL353600-1|CAI16997.1| 923|Homo sapiens neuropilin 1 protein.
Length = 923
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL121748-4|CAI40251.1| 704|Homo sapiens neuropilin 1 protein.
Length = 704
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL121748-3|CAI40249.1| 609|Homo sapiens neuropilin 1 protein.
Length = 609
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL121748-2|CAI40250.1| 644|Homo sapiens neuropilin 1 protein.
Length = 644
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>AL121748-1|CAI40248.1| 923|Homo sapiens neuropilin 1 protein.
Length = 923
Score = 116 bits (279), Expect = 3e-25
Identities = 86/283 (30%), Positives = 125/283 (44%), Gaps = 43/283 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + P I L F FDLE N C YD + + DV
Sbjct: 163 FPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVG 221
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 222 PHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 95.9 bits (228), Expect = 4e-19
Identities = 66/236 (27%), Positives = 111/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + P+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 80.2 bits (189), Expect = 2e-14
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + VP+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>BX510902-1|CAD91133.1| 923|Homo sapiens hypothetical protein
protein.
Length = 923
Score = 115 bits (277), Expect = 4e-25
Identities = 87/284 (30%), Positives = 127/284 (44%), Gaps = 45/284 (15%)
Query: 44 AFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENH 101
AF CG I+++S G+L SP YP Y P++ C W + P YQ + + F+ F++E+
Sbjct: 21 AFRNDKCGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDR 80
Query: 102 DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
D C YD V+V DG++ + G FCG KI P +S L I F+
Sbjct: 81 D-CKYDYVEVFDGENENGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFV 124
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+++ HG S I YE+ G +C P+G I SP
Sbjct: 125 SDYET-----HGAGFS-------------IRYEIFKRGPECSQN----YTTPSGVIKSPG 162
Query: 222 FPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVL 279
FPE YP C + + AP I L F FDLE N C YD + + G +
Sbjct: 163 FPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD--GFPGV 220
Query: 280 RRH-GAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI 322
H G +CG P + S +L + F +D ++ + GF+A Y +
Sbjct: 221 GPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSV 264
Score = 97.5 bits (232), Expect = 1e-19
Identities = 67/236 (28%), Positives = 112/236 (47%), Gaps = 10/236 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG +
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGENE 95
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEVKH 492
+ G FCG P V++S +++ F SD GF + G S
Sbjct: 96 NGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTTPS 155
Query: 493 LYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQVFX 546
+ Y + +C + + AP+ + L F +F+LE ++N CRYD ++++
Sbjct: 156 GVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWD 215
Query: 547 XXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 216 GFPGVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 271
Score = 83.4 bits (197), Expect = 2e-15
Identities = 50/120 (41%), Positives = 64/120 (53%), Gaps = 10/120 (8%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS 272
G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 37 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEVFD 91
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECAEN 330
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC++N
Sbjct: 92 GENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQN 150
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 101 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 158
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 159 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 217
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 218 PGVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 262
Score = 72.5 bits (170), Expect = 4e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 147 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 206
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 207 RYDRLEIWDGFPGVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 263
>BC117413-1|AAI17414.1| 926|Homo sapiens neuropilin 2 protein.
Length = 926
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>BC104770-1|AAI04771.1| 901|Homo sapiens neuropilin 2 protein.
Length = 901
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>BC101525-1|AAI01526.1| 901|Homo sapiens neuropilin 2 protein.
Length = 901
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF281074-4|AAG41899.1| 901|Homo sapiens neuropilin-2b(0) protein.
Length = 901
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF281074-3|AAG41900.1| 906|Homo sapiens neuropilin-2b(5) protein.
Length = 906
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF281074-2|AAG41897.1| 926|Homo sapiens neuropilin-2a(17) protein.
Length = 926
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF281074-1|AAG41898.1| 931|Homo sapiens neuropilin-2a(22) protein.
Length = 931
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF280546-1|AAG41405.1| 555|Homo sapiens neuropilin-2 soluble
isoform 9 protein.
Length = 555
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF280545-1|AAG41404.1| 906|Homo sapiens neuropilin-2b(5) protein.
Length = 906
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF280544-1|AAG41403.1| 901|Homo sapiens neuropilin-2b(O) protein.
Length = 901
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF022860-1|AAC51789.1| 926|Homo sapiens neuropilin-2(a17) protein.
Length = 926
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF022859-1|AAC51788.1| 909|Homo sapiens neuropilin-2(a0) protein.
Length = 909
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AF016098-1|AAC12922.1| 931|Homo sapiens vascular endothelial cell
growth factor 165 receptor 2 protein.
Length = 931
Score = 110 bits (265), Expect = 1e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 58.8 bits (136), Expect = 5e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AC007362-1|AAX93216.1| 808|Homo sapiens unknown protein.
Length = 808
Score = 110 bits (264), Expect = 2e-23
Identities = 71/231 (30%), Positives = 109/231 (47%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP YP YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIRFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 95.1 bits (226), Expect = 7e-19
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP YP DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIRFTSDYARQGAGFSLRY 139
Score = 86.2 bits (204), Expect = 3e-16
Identities = 50/133 (37%), Positives = 76/133 (57%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP +P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIRFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.0 bits (196), Expect = 3e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIRFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 60.1 bits (139), Expect = 2e-08
Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L +RF +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIRFTSDYARQGAGFSLRYEIFK 143
>BX537423-1|CAD97665.1| 931|Homo sapiens hypothetical protein
protein.
Length = 931
Score = 107 bits (256), Expect = 2e-22
Identities = 70/231 (30%), Positives = 108/231 (46%), Gaps = 11/231 (4%)
Query: 376 GTIFSPNYPAAYPARKDCVW-QFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASA 433
G I SP P YP+ ++C W ++ P +I L FN FE+E H +C YD + I DG S
Sbjct: 38 GYITSPGSPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSE 96
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
LG CG+ P +++S + +Y+ F SD + Q GF + G ++
Sbjct: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 494 YS--HARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER------EANCRYDYVQVF 545
+ Y DC + I A + L FL F+LE E +C+YD++ ++
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIW 216
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+CG K P E+ S++ L + F TD ++ GFSA Y +V
Sbjct: 217 DGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
Score = 91.5 bits (217), Expect = 8e-18
Identities = 45/113 (39%), Positives = 65/113 (57%), Gaps = 3/113 (2%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYD 107
CGG + G++ SP P DY ++ C W + P+ Q + L F+ FE+E HD C YD
Sbjct: 28 CGGRLNSKDAGYITSPGSPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+++RDGDS + L+G CG+ PP I S+ + L + F SD Q AGFS +
Sbjct: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Score = 84.2 bits (199), Expect = 1e-15
Identities = 50/133 (37%), Positives = 75/133 (56%), Gaps = 16/133 (12%)
Query: 206 CGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQE 262
CGG L + G ITSP P+ YP +NC W + AP P +I LNF HF++E + +
Sbjct: 28 CGGRLNSKDAGYITSPGSPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-----KHD 82
Query: 263 CEYDSVTVHS--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C+YD + + AD+L +H CG PP + S GS+L ++FTSD + +GF+ Y
Sbjct: 83 CKYDFIEIRDGDSESADLLGKH---CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
Query: 321 YI---DVDECAEN 330
I ++C++N
Sbjct: 140 EIFKTGSEDCSKN 152
Score = 83.4 bits (197), Expect = 2e-15
Identities = 54/169 (31%), Positives = 83/169 (49%), Gaps = 14/169 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN---- 59
A +LG+ CG+ P + S+GS L + + + GF YE G + N
Sbjct: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA-RQGAGFSLRYEIFKTGSEDCSKNFTSP 156
Query: 60 -GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDT-------CSYDKVKV 111
G +ESP +P+ Y N C + + ++ L+F F++E HD C YD + +
Sbjct: 157 NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVGEGDCKYDWLDI 215
Query: 112 RDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
DG PLIG +CG K P ++RS++ L + F +D V K GFSA +
Sbjct: 216 WDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
Score = 82.6 bits (195), Expect = 4e-15
Identities = 49/140 (35%), Positives = 72/140 (51%), Gaps = 6/140 (4%)
Query: 193 YELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFD 252
YE+ G + C PNGTI SP FPE YP +C + I+A P+ I L F FD
Sbjct: 139 YEIFKTGSE---DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFD 195
Query: 253 LEGNHMY--QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS 310
LE + + + +C+YD + + + V G +CGT P + S +L + F +D +
Sbjct: 196 LEHDPLQVGEGDCKYDWLDIWDGI-PHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMA 254
Query: 311 VHRSGFAAVYYIDVDECAEN 330
V + GF+A YY+ E EN
Sbjct: 255 VAKDGFSARYYLVHQEPLEN 274
Score = 73.7 bits (173), Expect = 2e-12
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 351 SGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFN 410
+GF+L C + T P+GTI SP +P YP DC + P I L F
Sbjct: 133 AGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL 192
Query: 411 VFELE--PHQ----ECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
+F+LE P Q +C YD + I+DG +G +CG+K P + +S + + F +D
Sbjct: 193 IFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD 252
Query: 465 GSVQRKGFLATH 476
+V + GF A +
Sbjct: 253 MAVAKDGFSARY 264
Score = 59.3 bits (137), Expect = 4e-08
Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 6/120 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPR-NHFVKLTFLT-FELEREANC 537
CGG L++ ++ ++ S D Y S +C+W + AP N + L F FE+E+ +C
Sbjct: 28 CGGRLNS-KDAGYITSPGSPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVK 597
+YD++++ CG PP I+S+ L ++F +D + GFS Y++ K
Sbjct: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
>AB209641-1|BAD92878.1| 890|Homo sapiens Neuropilin-1 precursor
variant protein.
Length = 890
Score = 106 bits (254), Expect = 3e-22
Identities = 81/267 (30%), Positives = 117/267 (43%), Gaps = 43/267 (16%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQ-VALRFHS-FEVENHDTCSYDKVKVRDGDSM 117
G+L SP YP Y P++ C W + P YQ + + F+ F++E+ D C YD V+V DG++
Sbjct: 4 GYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENE 62
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHS 177
+ G FCG KI P +S L I F+ +++ HG S
Sbjct: 63 NGHFRGKFCG-KIAPPPVVSSGPFLFI--------------KFVSDYET-----HGAGFS 102
Query: 178 CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIV 237
I YE+ G +C P+G I SP FPE YP C + +
Sbjct: 103 -------------IRYEIFKRGPECSQN----YTTPSGVIKSPGFPEKYPNSLECTYIVF 145
Query: 238 APPQHRITLNFTHFDLE--GNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT 295
AP I L F FDLE N C YD + + DV G +CG P +
Sbjct: 146 APKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF-PDVGPHIGRYCGQKTPGRIR 204
Query: 296 SDGSVLRVQFTSDGSVHRSGFAAVYYI 322
S +L + F +D ++ + GF+A Y +
Sbjct: 205 SSSGILSMVFYTDSAIAKEGFSANYSV 231
Score = 100 bits (239), Expect = 2e-20
Identities = 68/238 (28%), Positives = 113/238 (47%), Gaps = 10/238 (4%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTT-PGHRIKLIFNV-FELEPHQECAYDHVTIYDGA 431
P G + SP YP +Y + C W P RI + FN F+LE ++C YD+V ++DG
Sbjct: 2 PQGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLED-RDCKYDYVEVFDGE 60
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST-ACGGYLSATEEV 490
+ + G FCG P V++S +++ F SD GF + G S
Sbjct: 61 NENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECSQNYTT 120
Query: 491 KHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN------CRYDYVQV 544
+ Y + +C + + AP+ + L F +F+LE ++N CRYD +++
Sbjct: 121 PSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEI 180
Query: 545 FXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMVKPTWSD 602
+ +CG K P I S+S L + F TD ++ +GFSA+Y +++ + S+
Sbjct: 181 WDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSE 238
Score = 86.2 bits (204), Expect = 3e-16
Identities = 51/122 (41%), Positives = 65/122 (53%), Gaps = 10/122 (8%)
Query: 213 PNGTITSPSFPELYPPLKNCLWEIVAP-PQHRITLNFT-HFDLEGNHMYQQECEYDSVTV 270
P G +TSP +P Y P + C W I AP P RI +NF HFDLE ++C+YD V V
Sbjct: 2 PQGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLE-----DRDCKYDYVEV 56
Query: 271 HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI--DVDECA 328
+ R G FCG PPPV S G L ++F SD H +GF+ Y I EC+
Sbjct: 57 FDGENENGHFR-GKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPECS 115
Query: 329 EN 330
+N
Sbjct: 116 QN 117
Score = 78.6 bits (185), Expect = 6e-14
Identities = 54/165 (32%), Positives = 81/165 (49%), Gaps = 15/165 (9%)
Query: 8 GRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEVDSN-----GHL 62
G+ CG P + S+G L + + GF YE G E N G +
Sbjct: 68 GKFCGKIAPPPVVSSGPFLFIKFVSDYETHG-AGFSIRYEIFKRGP-ECSQNYTTPSGVI 125
Query: 63 ESPNYPDDYQPNKL-CIWKLSVPQDYQVALRFHSFEVENHDT------CSYDKVKVRDGD 115
+SP +P+ Y PN L C + + P+ ++ L F SF++E C YD++++ DG
Sbjct: 126 KSPGFPEKY-PNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDGF 184
Query: 116 SMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P IG +CG K P IRS+S L ++F +DS + K GFSA +
Sbjct: 185 PDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANY 229
Score = 71.7 bits (168), Expect = 7e-12
Identities = 38/117 (32%), Positives = 56/117 (47%), Gaps = 6/117 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQE------C 420
C + T P G I SP +P YP +C + I L F F+LEP C
Sbjct: 114 CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFC 173
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
YD + I+DG +G +CG K P + +S + MVF +D ++ ++GF A +S
Sbjct: 174 RYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYS 230
>Y18287-1|CAB50734.1| 185|Homo sapiens MAp19 protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y18286-1|CAB50732.1| 185|Homo sapiens MAp19 protein protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y18284-1|CAB50731.1| 185|Homo sapiens mannose binding
lectin-associated serine protease-2 related protein,
MAp19 (19k protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y18283-1|CAB50730.1| 185|Homo sapiens mannose binding
lectin-associated serine protease-2 related protein,
MAp19 (19k protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>Y18282-1|CAB50729.1| 175|Homo sapiens mannose binding
lectin-associated serine protease-2 related protein,
MAp19 (19k protein.
Length = 175
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 18 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 71
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 72 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 128
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 129 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 172
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 18 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 77
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 78 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 136
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 137 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 170
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 18 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 73
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 74 KVLATLCGQE 83
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 29 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 84
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 85 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 124
>Y18281-1|CAB50728.1| 185|Homo sapiens mannose binding
lectin-associated serine protease-2 related protein,
MAp19 (19k protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AL109811-5|CAI22103.1| 185|Homo sapiens mannan-binding lectin
serine peptidase 2 protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AF321558-1|AAG50275.1| 185|Homo sapiens MBL-associated protein
MAp19 protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AB033742-1|BAA85658.1| 185|Homo sapiens small MBL-associated
protein protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AB008047-1|BAA78616.1| 185|Homo sapiens small MBL-associated
protein protein.
Length = 185
Score = 103 bits (247), Expect = 2e-21
Identities = 68/164 (41%), Positives = 84/164 (51%), Gaps = 23/164 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+DEC G C H CHN LGG+ C+C +G+ LH NK C E
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSE 182
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>BC140003-1|AAI40004.1| 316|Homo sapiens Unknown (protein for
MGC:167002) protein.
Length = 316
Score = 101 bits (243), Expect = 6e-21
Identities = 94/304 (30%), Positives = 138/304 (45%), Gaps = 43/304 (14%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G NGTI SP FP YP NC W I+A ++RI + F F LE EY
Sbjct: 28 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE--------EY 79
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D ++++ R G LPPPVTS SV ++ TSD +V GF VYY ++
Sbjct: 80 DYLSLYDGHHHPTNFR-TRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF-KVYYEELQ 137
Query: 326 ECAENNGGCQHE--CHNT---LGG-YECACHSGFTL--HP------NKHD---------- 361
+ N G + + T +G +C +G+ L HP N +
Sbjct: 138 SSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPI 197
Query: 362 CK-EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
C+ E C + G I SP++P Y DC W PG I LIF F++E
Sbjct: 198 CRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---- 253
Query: 421 AYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTAC 480
YD++ I +G+ L G +P +++++N + + F +D + + +GF A +
Sbjct: 254 KYDYLEI-EGSEPPTIWLS---GMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGIL 309
Query: 481 GGYL 484
YL
Sbjct: 310 MEYL 313
Score = 95.5 bits (227), Expect = 5e-19
Identities = 81/296 (27%), Positives = 126/296 (42%), Gaps = 43/296 (14%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG ++ NG +ESP +P Y C W + + ++ + F SF +E YD +
Sbjct: 28 CGGTLK-GLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE----YDYL 82
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDECA 168
+ DG + G +PP + ST + + SD V GF + + + C
Sbjct: 83 SLYDGHHHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 142
Query: 169 S-------------IDHG--CSHSCVN--TLGGYECACDIGYELHSDGK-------KCEN 204
+ D G +SCV L G+ I +++ + E+
Sbjct: 143 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 202
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
ACGG + G +G I+SPSFP Y +C W IVA P I+L FT F Q E +
Sbjct: 203 ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDF--------QMEEK 254
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
YD + + + G +PPP+ S+ + LR+ F +D + GF+A Y
Sbjct: 255 YDYLEIEGSEPPTIW-----LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 305
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/114 (31%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 47 EAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSY 106
E CGG + S+G + SP++P++Y N C W + ++L F F++E Y
Sbjct: 201 EDACGGTMR-GSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----KY 255
Query: 107 DKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
D +++ + + P I + G IPP I S N L + F +DS + GFSA +
Sbjct: 256 DYLEI---EGSEPPTIWL-SGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 305
Score = 56.0 bits (129), Expect = 4e-07
Identities = 35/116 (30%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
ACGG + + + S N Y + ADC W I A + L F F++E +
Sbjct: 203 ACGGTMRGSSGIISSPSFP----NEYHNNADCTWTIVAEPGDTISLIFTDFQMEE----K 254
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
YDY+++ G+ +PP I+S L + F TD + ++GFSA YQ
Sbjct: 255 YDYLEI----EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 306
Score = 48.8 bits (111), Expect = 6e-05
Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 12/125 (9%)
Query: 470 KGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTF 529
KGF+ T CGG L YG Y + A+C W I A + +++ F +F
Sbjct: 22 KGFIYT----CGGTLKGLNGTIESPGFP-YG---YPNGANCTWVIIAEERNRIQIVFQSF 73
Query: 530 ELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGF 589
LE E YDY+ ++ G +PP + ST +R +D ++ GF
Sbjct: 74 ALEEE----YDYLSLYDGHHHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGF 129
Query: 590 SASYQ 594
Y+
Sbjct: 130 KVYYE 134
>AB033742-2|BAA85659.1| 181|Homo sapiens MBL-associated serine
protease(MASP)-2 protein.
Length = 181
Score = 101 bits (242), Expect = 8e-21
Identities = 67/162 (41%), Positives = 83/162 (51%), Gaps = 23/162 (14%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G + SP FP Y + W + APP +R+ L FTHFDLE +H+ CEYD V + S
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHL----CEYDFVKLSS-- 81
Query: 275 GADVLRRHGAFCG-----TALPP---PVTSDGSVLRVQFTSDGSVHR--SGFAAVYYI-D 323
GA VL CG T P S GS L + F SD S + +GF A Y D
Sbjct: 82 GAKVL---ATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAED 138
Query: 324 VDECAENNGG---CQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DEC G C H CHN LGG+ C+C +G+ LH NK C
Sbjct: 139 IDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 79.4 bits (187), Expect = 4e-14
Identities = 51/154 (33%), Positives = 74/154 (48%), Gaps = 12/154 (7%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G L SP +P +Y ++ W L+ P Y++ L F F++E C YD VK+ G + +
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 120 PLIGMFC--GHKIP--PDIRSTSNKLLVIFESDSTVQK--AGFSATFMKE-FDECASIDH 172
L G + P S + L + F SD + +K GF A + E DEC +
Sbjct: 88 TLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDEC-QVAP 146
Query: 173 G----CSHSCVNTLGGYECACDIGYELHSDGKKC 202
G C H C N LGG+ C+C GY LH + + C
Sbjct: 147 GEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180
Score = 50.0 bits (114), Expect = 3e-05
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G + SP +P Y ++ W + PG+R++L F F+LE C YD V + GA
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGA---- 83
Query: 436 KTLGIFCGSK 445
K L CG +
Sbjct: 84 KVLATLCGQE 93
Score = 33.1 bits (72), Expect = 3.1
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 14/100 (14%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCG--- 560
Y + + W + AP + ++L F F+LE C YD+V++ T CG
Sbjct: 39 YANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKL----SSGAKVLATLCGQES 94
Query: 561 --IKMPP---EIVSTSEALLVRFRTD--DSLVFKGFSASY 593
+ P S +L + FR+D + F GF A Y
Sbjct: 95 TDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFY 134
>AF448838-1|AAM18026.1| 533|Homo sapiens neuropilin and tolloid
like-1 protein.
Length = 533
Score = 96.7 bits (230), Expect = 2e-19
Identities = 52/201 (25%), Positives = 89/201 (44%), Gaps = 17/201 (8%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP+ YP ++C++ P I+L F+ + +EP EC +DH+ + DG
Sbjct: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS----------------T 478
+G FCG + P ++ +S +++ F +DG ++ GF A ++
Sbjct: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGALKPLP 170
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
AC + +E + + G DC W I AP + L FL +E++ C+
Sbjct: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
Query: 539 YDYVQVFXXXXXXXXXXXTFC 559
++V V+ FC
Sbjct: 231 RNFVAVYDGSSSVEDLKAKFC 251
Score = 78.6 bits (185), Expect = 6e-14
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDTCSYDK 108
CG + G SPNYP Y P++ CI+ + + L F + +E C +D
Sbjct: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SP+IG FCG + PP I+S+ L + F +D ++ GFSA +
Sbjct: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 152
Score = 71.7 bits (168), Expect = 7e-12
Identities = 65/260 (25%), Positives = 108/260 (41%), Gaps = 35/260 (13%)
Query: 211 YGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTV 270
+ G TSP++P YPP + C++ I A P+ I L +FD + + EC++D + V
Sbjct: 47 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIEL---YFDEKYSIEPSWECKFDHIEV 103
Query: 271 HS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
G + G FCG PP + S G L ++F +DG + GF+A Y D +
Sbjct: 104 RDGPFGFSPII--GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFK 161
Query: 330 NNGGCQ--HECHNTLGGYECACHSGFTLHPNKHDCKEG-GCKHDVTLPHGTIFSPNYPAA 386
+ G + C +GG E S + K E CK + P
Sbjct: 162 DLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAP------------ 209
Query: 387 YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKL 446
P +I L F +E++ EC + V +YDG+S+ FC +
Sbjct: 210 --------------PRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVA 255
Query: 447 PHLVMASQNQMYMVFKSDGS 466
+++ + + ++ +GS
Sbjct: 256 NDVMLRTGLGVIRMWADEGS 275
Score = 48.8 bits (111), Expect = 6e-05
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 5/128 (3%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELEREA 535
S CG + E +++ Y + Y +C + IEA ++L F + +E
Sbjct: 38 SVQCGTWTKHAEG--GIFTSPNY-PSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSW 94
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C++D+++V FCG + PP I S+ L ++F D L GFSA Y
Sbjct: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
Query: 596 V-KPTWSD 602
P + D
Sbjct: 155 TPDPDFKD 162
Score = 42.3 bits (95), Expect = 0.005
Identities = 47/199 (23%), Positives = 79/199 (39%), Gaps = 25/199 (12%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEV------- 56
+P++GR CG P+++S+G L + + L+ GF A Y D +
Sbjct: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELES-MGFSARYNFTPDPDFKDLGALKPL 169
Query: 57 --------DSNGHLESPNYPDDYQPNKL----CIWKLSVPQDYQVALRFHSFEVENHDTC 104
S G +ES + + C W + P ++ LRF +E++N + C
Sbjct: 170 PACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNEC 229
Query: 105 SYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+ V V DG S L FC + D+ + ++ +D + + F F F
Sbjct: 230 KRNFVAVYDGSSSVEDLKAKFCS-TVANDVMLRTGLGVIRMWADEGSRNSRFQMLF-TSF 287
Query: 165 DE--CASIDHGC-SHSCVN 180
E C C S+ C+N
Sbjct: 288 QEPPCEGNTFFCHSNMCIN 306
>AK122760-1|BAC85509.1| 157|Homo sapiens protein ( Homo sapiens
cDNA FLJ16295 fis, clone OCBBF2033869, weakly similar
to PROCOLLAGEN C-PROTEINASE ENHANCER PROTEIN PRECURSOR.
).
Length = 157
Score = 95.1 bits (226), Expect = 7e-19
Identities = 52/132 (39%), Positives = 73/132 (55%), Gaps = 8/132 (6%)
Query: 32 PGLRLKPHRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVAL 91
PGL+ + G + CGG + S G+ SPN+P Y N C W + V + V L
Sbjct: 18 PGLQAQAMEGVK------CGGVLSAPS-GNFSSPNFPRLYPYNTECSWLIVVAEGSSVLL 70
Query: 92 RFHSFEVENHDTCSYDKVKVRDGDSMD-SPLIGMFCGHKIPPDIRSTSNKLLVIFESDST 150
FH+F++E HDTCS+D +++ +G S D L+G FCG PP S+ + + VIF SD
Sbjct: 71 TFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKH 130
Query: 151 VQKAGFSATFMK 162
V GFSA + K
Sbjct: 131 VASHGFSAGYQK 142
Score = 87.8 bits (208), Expect = 1e-16
Identities = 46/115 (40%), Positives = 57/115 (49%), Gaps = 4/115 (3%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L P+G +SP+FP LYP C W IV + L F FDLE Y C +
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLE----YHDTCSF 85
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + +++ D G FCG PPP TS V+ V F SD V GF+A Y
Sbjct: 86 DFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGY 140
Score = 84.6 bits (200), Expect = 1e-15
Identities = 45/128 (35%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C ++ P G SPN+P YP +C W G + L F+ F+LE H C++D +
Sbjct: 30 CGGVLSAPSGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLE 89
Query: 427 IYDGASADV-KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLS 485
IY+GAS D LG FCG P +S + M ++F SD V GF A + G L
Sbjct: 90 IYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKGQRGALG 149
Query: 486 ATEEVKHL 493
HL
Sbjct: 150 TCCSGSHL 157
Score = 58.4 bits (135), Expect = 7e-08
Identities = 36/122 (29%), Positives = 50/122 (40%), Gaps = 5/122 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A CGG LSA +S + Y +C W I V LTF F+LE
Sbjct: 24 AMEGVKCGGVLSAPSGN---FSSPNF-PRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEY 79
Query: 534 EANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSAS 592
C +D+++++ FCG PP S+ + V F +D + GFSA
Sbjct: 80 HDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFSAG 139
Query: 593 YQ 594
YQ
Sbjct: 140 YQ 141
>AJ297949-2|CAC17139.1| 136|Homo sapiens MASP-2 protein protein.
Length = 136
Score = 94.7 bits (225), Expect = 9e-19
Identities = 49/136 (36%), Positives = 64/136 (47%), Gaps = 7/136 (5%)
Query: 334 CQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDC 393
C H CHN LGG+ C+C +G+ LH NK C T G + SP YP YP C
Sbjct: 4 CDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSC 63
Query: 394 VWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGASADVKTLGIFCGSKLPHLV 450
+ S G + L F F++E H E C YD + I D + G FCG LPH +
Sbjct: 64 TYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCGKTLPHRI 119
Query: 451 MASQNQMYMVFKSDGS 466
N + + F +D S
Sbjct: 120 ETKSNTVTITFVTDES 135
Score = 86.2 bits (204), Expect = 3e-16
Identities = 43/139 (30%), Positives = 69/139 (49%), Gaps = 9/139 (6%)
Query: 174 CSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGP-NGTITSPSFPELYPPLKNC 232
C H C N LGG+ C+C GY LH + + C C G ++ +G ++SP +P YP L +C
Sbjct: 4 CDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSC 63
Query: 233 LWEIVAPPQHRITLNFTH-FDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALP 291
+ I + L+F FD+E + + C YD + + + HG FCG LP
Sbjct: 64 TYSISLEEGFSVILDFVESFDVETHP--ETLCPYDFLKIQTD-----REEHGPFCGKTLP 116
Query: 292 PPVTSDGSVLRVQFTSDGS 310
+ + + + + F +D S
Sbjct: 117 HRIETKSNTVTITFVTDES 135
Score = 64.9 bits (151), Expect = 8e-10
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Query: 39 HRGFRAFYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFE 97
HR R A+C G + +G L SP YP Y C + +S+ + + V L F SF+
Sbjct: 26 HRNKRTC-SALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDFVESFD 84
Query: 98 VENH--DTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDST 150
VE H C YD +K++ D G FCG +P I + SN + + F +D +
Sbjct: 85 VETHPETLCPYDFLKIQ----TDREEHGPFCGKTLPHRIETKSNTVTITFVTDES 135
Score = 33.5 bits (73), Expect = 2.4
Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFL-TFELER--EANCRYDYVQVFXXXXXXXXXXXTFCG 560
Y + C ++I V L F+ +F++E E C YD++++ FCG
Sbjct: 57 YPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKI----QTDREEHGPFCG 112
Query: 561 IKMPPEIVSTSEALLVRFRTDDS 583
+P I + S + + F TD+S
Sbjct: 113 KTLPHRIETKSNTVTITFVTDES 135
>BC050329-1|AAH50329.1| 533|Homo sapiens NETO1 protein protein.
Length = 533
Score = 93.5 bits (222), Expect = 2e-18
Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 17/201 (8%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP+ YP ++C++ P I+L F+ + +EP EC +DH+ + DG
Sbjct: 51 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 110
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS----------------T 478
+G FCG + P ++ +S +++ F + G ++ GF A ++
Sbjct: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFAAGELESMGFSARYNFTPDPDFKDLGALKPLP 170
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
AC + +E + + G DC W I AP + L FL +E++ C+
Sbjct: 171 ACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECK 230
Query: 539 YDYVQVFXXXXXXXXXXXTFC 559
++V V+ FC
Sbjct: 231 RNFVAVYDGSSSVEDLKAKFC 251
Score = 75.4 bits (177), Expect = 6e-13
Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDTCSYDK 108
CG + G SPNYP Y P++ CI+ + + L F + +E C +D
Sbjct: 41 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 100
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SP+IG FCG + PP I+S+ L + F + ++ GFSA +
Sbjct: 101 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAAGELESMGFSARY 152
Score = 68.5 bits (160), Expect = 7e-11
Identities = 64/260 (24%), Positives = 107/260 (41%), Gaps = 35/260 (13%)
Query: 211 YGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTV 270
+ G TSP++P YPP + C++ I A P+ I L +FD + + EC++D + V
Sbjct: 47 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIEL---YFDEKYSIEPSWECKFDHIEV 103
Query: 271 H-SKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAE 329
G + G FCG PP + S G L ++F + G + GF+A Y D +
Sbjct: 104 RDGPFGFSPI--IGRFCGQQNPPVIKSSGRFLWIKFFAAGELESMGFSARYNFTPDPDFK 161
Query: 330 NNGGCQ--HECHNTLGGYECACHSGFTLHPNKHDCKEG-GCKHDVTLPHGTIFSPNYPAA 386
+ G + C +GG E S + K E CK + P
Sbjct: 162 DLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAP------------ 209
Query: 387 YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKL 446
P +I L F +E++ EC + V +YDG+S+ FC +
Sbjct: 210 --------------PRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVA 255
Query: 447 PHLVMASQNQMYMVFKSDGS 466
+++ + + ++ +GS
Sbjct: 256 NDVMLRTGLGVIRMWADEGS 275
Score = 45.6 bits (103), Expect = 5e-04
Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 5/128 (3%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELEREA 535
S CG + E +++ Y + Y +C + IEA ++L F + +E
Sbjct: 38 SVQCGTWTKHAEG--GIFTSPNY-PSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSW 94
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C++D+++V FCG + PP I S+ L ++F L GFSA Y
Sbjct: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFAAGELESMGFSARYNF 154
Query: 596 V-KPTWSD 602
P + D
Sbjct: 155 TPDPDFKD 162
Score = 42.7 bits (96), Expect = 0.004
Identities = 47/199 (23%), Positives = 79/199 (39%), Gaps = 25/199 (12%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCGGDIEV------- 56
+P++GR CG P+++S+G L + + L+ GF A Y D +
Sbjct: 111 SPIIGRFCGQQNPPVIKSSGRFLWIKFFAAGELES-MGFSARYNFTPDPDFKDLGALKPL 169
Query: 57 --------DSNGHLESPNYPDDYQPNKL----CIWKLSVPQDYQVALRFHSFEVENHDTC 104
S G +ES + + C W + P ++ LRF +E++N + C
Sbjct: 170 PACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNEC 229
Query: 105 SYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+ V V DG S L FC + D+ + ++ +D + + F F F
Sbjct: 230 KRNFVAVYDGSSSVEDLKAKFCS-TVANDVMLRTGLGVIRMWADEGSRNSRFQMLF-TSF 287
Query: 165 DE--CASIDHGC-SHSCVN 180
E C C S+ C+N
Sbjct: 288 QEPPCEGNTFFCHSNMCIN 306
>AY358718-1|AAQ89080.1| 525|Homo sapiens Neto2 protein.
Length = 525
Score = 93.1 bits (221), Expect = 3e-18
Identities = 58/202 (28%), Positives = 92/202 (45%), Gaps = 18/202 (8%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP +YP K+C++ P RI+L F+ + +EP EC +DH+ + DG
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-------TACGGYLSAT 487
+ +CG K P L+ ++ M++ F SD ++ GF A +S T GG L+
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
Query: 488 EEVKHLYSHA----RYGDNAYESR------ADCDWNIEAPRNHFVKLTFLTFELEREANC 537
+ + S A R E + DC W I+A + L FL +++E C
Sbjct: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
Query: 538 RYDYVQVFXXXXXXXXXXXTFC 559
+ ++V V+ FC
Sbjct: 235 KRNFVAVYDGSSSIENLKAKFC 256
Score = 91.5 bits (217), Expect = 8e-18
Identities = 45/112 (40%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDK 108
CG + + GH SPNYPD Y PNK CI+ L ++ L F + +E C +D
Sbjct: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SPLI +CG K PP IRST + + F SD ++ GF A +
Sbjct: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVH-S 272
G SP++P+ YPP K C++ + A P+ RI L F H+ +E + EC +D + V
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSF----ECRFDHLEVRDG 110
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G L +CG PP + S G + ++F+SD + GF A Y
Sbjct: 111 PFGFSPL--IDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G +T CG ++ T H ++ Y D+ Y +C + +EA ++LTF
Sbjct: 33 QNIGIKHIPATQCGIWVR-TSNGGH-FASPNYPDS-YPPNKECIYILEAAPRQRIELTFD 89
Query: 528 T-FELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
+ +E CR+D+++V +CG+K PP I ST + ++F +D+ L
Sbjct: 90 EHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG 149
Query: 587 KGFSASYQMV 596
GF A Y +
Sbjct: 150 LGFRAKYSFI 159
Score = 44.8 bits (101), Expect = 0.001
Identities = 20/75 (26%), Positives = 38/75 (50%)
Query: 392 DCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM 451
DC+W TP +I L F +++E EC + V +YDG+S+ FC + +++
Sbjct: 206 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
Query: 452 ASQNQMYMVFKSDGS 466
+ + ++ +GS
Sbjct: 266 KTGIGVIRMWADEGS 280
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV-------CGG---- 52
+P++ R CG P++RSTG + + + L+ GFRA Y + GG
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG-LGFRAKYSFIPDPDFTYLGGILNP 173
Query: 53 --DIEVDSNG-----HLESPNYPDDYQPNKL--CIWKLSVPQDYQVALRFHSFEVENHDT 103
D + + +G + +P + CIW + ++ LRF +++E+ +
Sbjct: 174 IPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNE 233
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C + V V DG S L FC + D+ + ++ +D + + F F
Sbjct: 234 CKRNFVAVYDGSSSIENLKAKFCS-TVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSF 292
Query: 164 FD-ECASIDHGC-SHSCVN 180
+ C S C S+ C+N
Sbjct: 293 VEPPCTSSTFFCHSNMCIN 311
Score = 35.1 bits (77), Expect = 0.77
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 13/153 (8%)
Query: 231 NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTAL 290
+C+W I A P+ +I L F + +E + EC+ + V V+ + + FC T
Sbjct: 206 DCIWTIKATPKAKIYLRFLDYQME----HSNECKRNFVAVYDG-SSSIENLKAKFCSTVA 260
Query: 291 PPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD-ECAENNGGC-QHECHNTLGGYECA 348
+ G + + +GS S F ++ V+ C + C + C N C
Sbjct: 261 NDVMLKTGIGVIRMWADEGS-RLSRFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCN 317
Query: 349 CHSGFTLHPNKHDCKE---GGCKHDVTLPHGTI 378
+++ CKE G +T HGTI
Sbjct: 318 GVQNCAYPWDENHCKEKKKAGVFEQITKTHGTI 350
>AK074937-1|BAC11303.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ90456 fis, clone NT2RP3001650, weakly similar to
BONE MORPHOGENETIC PROTEIN 1 PRECURSOR (EC 3.4.24.-). ).
Length = 525
Score = 93.1 bits (221), Expect = 3e-18
Identities = 58/202 (28%), Positives = 92/202 (45%), Gaps = 18/202 (8%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP +YP K+C++ P RI+L F+ + +EP EC +DH+ + DG
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS-------TACGGYLSAT 487
+ +CG K P L+ ++ M++ F SD ++ GF A +S T GG L+
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPI 174
Query: 488 EEVKHLYSHA----RYGDNAYESR------ADCDWNIEAPRNHFVKLTFLTFELEREANC 537
+ + S A R E + DC W I+A + L FL +++E C
Sbjct: 175 PDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNEC 234
Query: 538 RYDYVQVFXXXXXXXXXXXTFC 559
+ ++V V+ FC
Sbjct: 235 KRNFVAVYDGSSSIENLKAKFC 256
Score = 91.5 bits (217), Expect = 8e-18
Identities = 45/112 (40%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDK 108
CG + + GH SPNYPD Y PNK CI+ L ++ L F + +E C +D
Sbjct: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SPLI +CG K PP IRST + + F SD ++ GF A +
Sbjct: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 36/108 (33%), Positives = 55/108 (50%), Gaps = 8/108 (7%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVH-S 272
G SP++P+ YPP K C++ + A P+ RI L F H+ +E + EC +D + V
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSF----ECRFDHLEVRDG 110
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G L +CG PP + S G + ++F+SD + GF A Y
Sbjct: 111 PFGFSPL--IDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G +T CG ++ T H ++ Y D+ Y +C + +EA ++LTF
Sbjct: 33 QNIGIKHIPATQCGIWVR-TSNGGH-FASPNYPDS-YPPNKECIYILEAAPRQRIELTFD 89
Query: 528 T-FELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
+ +E CR+D+++V +CG+K PP I ST + ++F +D+ L
Sbjct: 90 EHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG 149
Query: 587 KGFSASYQMV 596
GF A Y +
Sbjct: 150 LGFRAKYSFI 159
Score = 44.8 bits (101), Expect = 0.001
Identities = 20/75 (26%), Positives = 38/75 (50%)
Query: 392 DCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM 451
DC+W TP +I L F +++E EC + V +YDG+S+ FC + +++
Sbjct: 206 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 265
Query: 452 ASQNQMYMVFKSDGS 466
+ + ++ +GS
Sbjct: 266 KTGIGVIRMWADEGS 280
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV-------CGG---- 52
+P++ R CG P++RSTG + + + L+ GFRA Y + GG
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG-LGFRAKYSFIPDPDFTYLGGILNP 173
Query: 53 --DIEVDSNG-----HLESPNYPDDYQPNKL--CIWKLSVPQDYQVALRFHSFEVENHDT 103
D + + +G + +P + CIW + ++ LRF +++E+ +
Sbjct: 174 IPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNE 233
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C + V V DG S L FC + D+ + ++ +D + + F F
Sbjct: 234 CKRNFVAVYDGSSSIENLKAKFCS-TVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSF 292
Query: 164 FD-ECASIDHGC-SHSCVN 180
+ C S C S+ C+N
Sbjct: 293 VEPPCTSSTFFCHSNMCIN 311
Score = 35.1 bits (77), Expect = 0.77
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 13/153 (8%)
Query: 231 NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTAL 290
+C+W I A P+ +I L F + +E + EC+ + V V+ + + FC T
Sbjct: 206 DCIWTIKATPKAKIYLRFLDYQME----HSNECKRNFVAVYDG-SSSIENLKAKFCSTVA 260
Query: 291 PPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD-ECAENNGGC-QHECHNTLGGYECA 348
+ G + + +GS S F ++ V+ C + C + C N C
Sbjct: 261 NDVMLKTGIGVIRMWADEGS-RLSRFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCN 317
Query: 349 CHSGFTLHPNKHDCKE---GGCKHDVTLPHGTI 378
+++ CKE G +T HGTI
Sbjct: 318 GVQNCAYPWDENHCKEKKKAGVFEQITKTHGTI 350
>BC108727-1|AAI08728.1| 329|Homo sapiens Unknown (protein for
IMAGE:6166566) protein.
Length = 329
Score = 92.3 bits (219), Expect = 5e-18
Identities = 53/195 (27%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP +YP K+C++ P RI+L F+ + +EP EC +DH+ + DG
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGF 114
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTA----------CGGYL 484
+ +CG K P L+ ++ M++ F SD ++ GF A +S C L
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGDCQFEL 174
Query: 485 SATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQV 544
S + + + DC W I+A + L FL +++E C+ ++V V
Sbjct: 175 SGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAV 234
Query: 545 FXXXXXXXXXXXTFC 559
+ FC
Sbjct: 235 YDGSSSIENLKAKFC 249
Score = 91.5 bits (217), Expect = 8e-18
Identities = 45/112 (40%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS-FEVENHDTCSYDK 108
CG + + GH SPNYPD Y PNK CI+ L ++ L F + +E C +D
Sbjct: 45 CGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDH 104
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SPLI +CG K PP IRST + + F SD ++ GF A +
Sbjct: 105 LEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKY 156
Score = 66.1 bits (154), Expect = 4e-10
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVH-S 272
G SP++P+ YPP K C++ + A P+ RI L F H+ +E + EC +D + V
Sbjct: 55 GHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSF----ECRFDHLEVRDG 110
Query: 273 KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNG 332
G L +CG PP + S G + ++F+SD + GF A Y D G
Sbjct: 111 PFGFSPL--IDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLG 168
Query: 333 GCQHE 337
CQ E
Sbjct: 169 DCQFE 173
Score = 57.2 bits (132), Expect = 2e-07
Identities = 36/130 (27%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 468 QRKGFLATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFL 527
Q G +T CG ++ T H ++ Y D+ Y +C + +EA ++LTF
Sbjct: 33 QNIGIKHIPATQCGIWVR-TSNGGH-FASPNYPDS-YPPNKECIYILEAAPRQRIELTFD 89
Query: 528 T-FELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVF 586
+ +E CR+D+++V +CG+K PP I ST + ++F +D+ L
Sbjct: 90 EHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG 149
Query: 587 KGFSASYQMV 596
GF A Y +
Sbjct: 150 LGFRAKYSFI 159
Score = 49.6 bits (113), Expect = 3e-05
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 17/192 (8%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAVCG------GDIEVD 57
+P++ R CG P++RSTG + + + L+ GFRA Y + GD + +
Sbjct: 115 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG-LGFRAKYSFIPDPDFTYLGDCQFE 173
Query: 58 SNG-----HLESPNYPDDYQPNKL--CIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVK 110
+G + +P + CIW + ++ LRF +++E+ + C + V
Sbjct: 174 LSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVA 233
Query: 111 VRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFD-ECAS 169
V DG S L FC + D+ + ++ +D + + F F + C S
Sbjct: 234 VYDGSSSIENLKAKFCS-TVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTS 292
Query: 170 IDHGC-SHSCVN 180
C S+ C+N
Sbjct: 293 STFFCHSNMCIN 304
Score = 44.8 bits (101), Expect = 0.001
Identities = 20/75 (26%), Positives = 38/75 (50%)
Query: 392 DCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM 451
DC+W TP +I L F +++E EC + V +YDG+S+ FC + +++
Sbjct: 199 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 258
Query: 452 ASQNQMYMVFKSDGS 466
+ + ++ +GS
Sbjct: 259 KTGIGVIRMWADEGS 273
Score = 31.5 bits (68), Expect = 9.5
Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 5/80 (6%)
Query: 231 NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTAL 290
+C+W I A P+ +I L F + +E + EC+ + V V+ + + FC T
Sbjct: 199 DCIWTIKATPKAKIYLRFLDYQME----HSNECKRNFVAVYDG-SSSIENLKAKFCSTVA 253
Query: 291 PPPVTSDGSVLRVQFTSDGS 310
+ G + + +GS
Sbjct: 254 NDVMLKTGIGVIRMWADEGS 273
>AY358556-1|AAQ88920.1| 607|Homo sapiens ERG-1 protein.
Length = 607
Score = 89.0 bits (211), Expect = 4e-17
Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 14/215 (6%)
Query: 391 KDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK--LPH 448
++C W I++IF+ +L+P C +++ ++DG S++ LG C +P
Sbjct: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
Query: 449 LVMASQNQMYMVFKSDGSVQRKGFLATHSTA-------CGGYLSATEEVKHLYSHARYGD 501
+S + + +QR F+ + + CGGYL E ++ Y
Sbjct: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLE---GSFTSPNY-P 171
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
+ A C W+I+ +++ +KL F LE + C++D++ ++ CG
Sbjct: 172 KPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG- 230
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++ P S+S +L V TD + ++GFSASY +
Sbjct: 231 RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
Score = 85.0 bits (201), Expect = 7e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 14/174 (8%)
Query: 3 DAPVLGRLCGSGKG-PMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV--------CGG 52
+ P+LG++C P+ S+ S LT + R++ R FY CGG
Sbjct: 99 NGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQ--RTVFVFYYFFSPNISIPNCGG 156
Query: 53 DIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVR 112
++ G SPNYP + C+W + V +DY++ L F +E C +D + +
Sbjct: 157 YLDT-LEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIY 215
Query: 113 DGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DG S +S LIG CG ++ P S+SN L V+ +D GFSA++ + E
Sbjct: 216 DGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
Score = 70.1 bits (164), Expect = 2e-11
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G+ SPNYP +P CVW ++IKL F LE ++C +D + IYDG S +
Sbjct: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSAT 487
+G CG P +S N + +V +D + +GF A++++ ++ T
Sbjct: 223 GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTT 273
Score = 56.8 bits (131), Expect = 2e-07
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G+ TSP++P+ +P L C+W I ++I LNF LE ++C++
Sbjct: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLE----IDKQCKF 209
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + ++ + G CG P +S S+ V T + +R GF+A Y
Sbjct: 210 DFLAIYDGPSTN-SGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYR-GFSASY 262
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 73 PNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCG-HKIP 131
P++ C W + P++ + + F +++ +C + +KV DG S + PL+G C +
Sbjct: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
Query: 132 PDIRSTSNKLLVIFESDST-VQKAGF 156
P S+S+ L +DS +Q+ F
Sbjct: 114 PVFESSSSTLTFQIVTDSARIQRTVF 139
Score = 33.5 bits (73), Expect = 2.4
Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+C +L G N T + P +NC W I P I + F++ L+ + CE
Sbjct: 31 SCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPD----GSCE 86
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS-VHRSGFAAVYYID 323
+++ V ++ P S S L Q +D + + R+ F Y+
Sbjct: 87 SENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFS 146
Query: 324 VDECAENNGG 333
+ N GG
Sbjct: 147 PNISIPNCGG 156
>AY260047-1|AAP15458.1| 607|Homo sapiens transmembrane protein
UO-44D protein.
Length = 607
Score = 89.0 bits (211), Expect = 4e-17
Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 14/215 (6%)
Query: 391 KDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK--LPH 448
++C W I++IF+ +L+P C +++ ++DG S++ LG C +P
Sbjct: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
Query: 449 LVMASQNQMYMVFKSDGSVQRKGFLATHSTA-------CGGYLSATEEVKHLYSHARYGD 501
+S + + +QR F+ + + CGGYL E ++ Y
Sbjct: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLE---GSFTSPNY-P 171
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
+ A C W+I+ +++ +KL F LE + C++D++ ++ CG
Sbjct: 172 KPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG- 230
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++ P S+S +L V TD + ++GFSASY +
Sbjct: 231 RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
Score = 85.0 bits (201), Expect = 7e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 14/174 (8%)
Query: 3 DAPVLGRLCGSGKG-PMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV--------CGG 52
+ P+LG++C P+ S+ S LT + R++ R FY CGG
Sbjct: 99 NGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQ--RTVFVFYYFFSPNISIPNCGG 156
Query: 53 DIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVR 112
++ G SPNYP + C+W + V +DY++ L F +E C +D + +
Sbjct: 157 YLDT-LEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIY 215
Query: 113 DGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DG S +S LIG CG ++ P S+SN L V+ +D GFSA++ + E
Sbjct: 216 DGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
Score = 70.1 bits (164), Expect = 2e-11
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G+ SPNYP +P CVW ++IKL F LE ++C +D + IYDG S +
Sbjct: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSAT 487
+G CG P +S N + +V +D + +GF A++++ ++ T
Sbjct: 223 GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTT 273
Score = 56.8 bits (131), Expect = 2e-07
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G+ TSP++P+ +P L C+W I ++I LNF LE ++C++
Sbjct: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLE----IDKQCKF 209
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + ++ + G CG P +S S+ V T + +R GF+A Y
Sbjct: 210 DFLAIYDGPSTN-SGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYR-GFSASY 262
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 73 PNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCG-HKIP 131
P++ C W + P++ + + F +++ +C + +KV DG S + PL+G C +
Sbjct: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
Query: 132 PDIRSTSNKLLVIFESDST-VQKAGF 156
P S+S+ L +DS +Q+ F
Sbjct: 114 PVFESSSSTLTFQIVTDSARIQRTVF 139
Score = 33.5 bits (73), Expect = 2.4
Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+C +L G N T + P +NC W I P I + F++ L+ + CE
Sbjct: 31 SCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPD----GSCE 86
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS-VHRSGFAAVYYID 323
+++ V ++ P S S L Q +D + + R+ F Y+
Sbjct: 87 SENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFS 146
Query: 324 VDECAENNGG 333
+ N GG
Sbjct: 147 PNISIPNCGG 156
>AL359747-4|CAH70006.1| 607|Homo sapiens CUB and zona
pellucida-like domains 1 protein.
Length = 607
Score = 89.0 bits (211), Expect = 4e-17
Identities = 52/215 (24%), Positives = 98/215 (45%), Gaps = 14/215 (6%)
Query: 391 KDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK--LPH 448
++C W I++IF+ +L+P C +++ ++DG S++ LG C +P
Sbjct: 56 ENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPV 115
Query: 449 LVMASQNQMYMVFKSDGSVQRKGFLATHSTA-------CGGYLSATEEVKHLYSHARYGD 501
+S + + +QR F+ + + CGGYL E ++ Y
Sbjct: 116 FESSSSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPNCGGYLDTLE---GSFTSPNY-P 171
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
+ A C W+I+ +++ +KL F LE + C++D++ ++ CG
Sbjct: 172 KPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCG- 230
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++ P S+S +L V TD + ++GFSASY +
Sbjct: 231 RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSI 265
Score = 85.0 bits (201), Expect = 7e-16
Identities = 53/174 (30%), Positives = 83/174 (47%), Gaps = 14/174 (8%)
Query: 3 DAPVLGRLCGSGKG-PMMRSTGSRLTV-VYQPGLRLKPHRGFRAFYEAV--------CGG 52
+ P+LG++C P+ S+ S LT + R++ R FY CGG
Sbjct: 99 NGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQ--RTVFVFYYFFSPNISIPNCGG 156
Query: 53 DIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVR 112
++ G SPNYP + C+W + V +DY++ L F +E C +D + +
Sbjct: 157 YLDT-LEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIY 215
Query: 113 DGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DG S +S LIG CG ++ P S+SN L V+ +D GFSA++ + E
Sbjct: 216 DGPSTNSGLIGQVCG-RVTPTFESSSNSLTVVLSTDYANSYRGFSASYTSIYAE 268
Score = 70.1 bits (164), Expect = 2e-11
Identities = 35/112 (31%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
G+ SPNYP +P CVW ++IKL F LE ++C +D + IYDG S +
Sbjct: 163 GSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLEIDKQCKFDFLAIYDGPSTNS 222
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSAT 487
+G CG P +S N + +V +D + +GF A++++ ++ T
Sbjct: 223 GLIGQVCGRVTP-TFESSSNSLTVVLSTDYANSYRGFSASYTSIYAENINTT 273
Score = 56.8 bits (131), Expect = 2e-07
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L G+ TSP++P+ +P L C+W I ++I LNF LE ++C++
Sbjct: 154 CGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIKLNFKEIFLE----IDKQCKF 209
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
D + ++ + G CG P +S S+ V T + +R GF+A Y
Sbjct: 210 DFLAIYDGPSTN-SGLIGQVCGRVTPTFESSSNSLTVVLSTDYANSYR-GFSASY 262
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 73 PNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCG-HKIP 131
P++ C W + P++ + + F +++ +C + +KV DG S + PL+G C +
Sbjct: 54 PSENCTWTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYV 113
Query: 132 PDIRSTSNKLLVIFESDST-VQKAGF 156
P S+S+ L +DS +Q+ F
Sbjct: 114 PVFESSSSTLTFQIVTDSARIQRTVF 139
Score = 33.5 bits (73), Expect = 2.4
Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 5/130 (3%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+C +L G N T + P +NC W I P I + F++ L+ + CE
Sbjct: 31 SCTVSLGGANMAETHKAMILQLNPSENCTWTIERPENKSIRIIFSYVQLDPD----GSCE 86
Query: 265 YDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGS-VHRSGFAAVYYID 323
+++ V ++ P S S L Q +D + + R+ F Y+
Sbjct: 87 SENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSARIQRTVFVFYYFFS 146
Query: 324 VDECAENNGG 333
+ N GG
Sbjct: 147 PNISIPNCGG 156
>BC089434-1|AAH89434.1| 737|Homo sapiens regeneration associated
muscle protease protein.
Length = 737
Score = 86.2 bits (204), Expect = 3e-16
Identities = 48/137 (35%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Query: 69 DDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGH 128
+ Y N C W + + + LRF +E C YD V+VRDGD+ D +I CG+
Sbjct: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
Query: 129 KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCV-NTLGGYEC 187
+ P I+S + L V+F SD + GF A + +E C+S +CV + G Y+C
Sbjct: 202 ERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY-EEITACSSSPCFHDGTCVLDKAGSYKC 260
Query: 188 ACDIGYELHSDGKKCEN 204
AC GY G++CEN
Sbjct: 261 ACLAGY----TGQRCEN 273
Score = 79.0 bits (186), Expect = 5e-14
Identities = 67/199 (33%), Positives = 93/199 (46%), Gaps = 27/199 (13%)
Query: 164 FDECASIDHGCSHSCVNT--LGGYECA-CDIGYELHSDGKKCENACGGALYGPNGTITSP 220
F+ C S +G ++ + G+ CA C G+ G C CG L P G I
Sbjct: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR-CGQVLRAPKGQILLE 142
Query: 221 SFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGAD--V 278
S YP +C W I A P I L F LE ++M C+YD V V D +
Sbjct: 143 S----YPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYM----CQYDYVEVRDGDNRDGQI 194
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHE- 337
++R CG P P+ S GS L V F SDGS + GF A+Y ++ C ++ C H+
Sbjct: 195 IKR---VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE-EITAC--SSSPCFHDG 248
Query: 338 -C-HNTLGGYECACHSGFT 354
C + G Y+CAC +G+T
Sbjct: 249 TCVLDKAGSYKCACLAGYT 267
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 344 GYECA-CHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG 402
G+ CA C +G+ DC C + P G I +YP C W PG
Sbjct: 110 GFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILLESYPL----NAHCEWTIHAKPG 159
Query: 403 HRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFK 462
I+L F + LE C YD+V + DG + D + + CG++ P + + + ++++F
Sbjct: 160 FVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFH 219
Query: 463 SDGSVQRKGFLATHS--TAC 480
SDGS GF A + TAC
Sbjct: 220 SDGSKNFDGFHAIYEEITAC 239
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/94 (32%), Positives = 44/94 (46%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIK 562
+Y A C+W I A ++L F+ LE + C+YDYV+V CG +
Sbjct: 143 SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE 202
Query: 563 MPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P I S +L V F +D S F GF A Y+ +
Sbjct: 203 RPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
>AY358346-1|AAQ88712.1| 720|Homo sapiens ELGC699 protein.
Length = 720
Score = 86.2 bits (204), Expect = 3e-16
Identities = 48/137 (35%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Query: 69 DDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGH 128
+ Y N C W + + + LRF +E C YD V+VRDGD+ D +I CG+
Sbjct: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
Query: 129 KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCV-NTLGGYEC 187
+ P I+S + L V+F SD + GF A + +E C+S +CV + G Y+C
Sbjct: 202 ERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY-EEITACSSSPCFHDGTCVLDKAGSYKC 260
Query: 188 ACDIGYELHSDGKKCEN 204
AC GY G++CEN
Sbjct: 261 ACLAGY----TGQRCEN 273
Score = 79.4 bits (187), Expect = 4e-14
Identities = 69/212 (32%), Positives = 98/212 (46%), Gaps = 27/212 (12%)
Query: 164 FDECASIDHGCSHSCVNT--LGGYECA-CDIGYELHSDGKKCENACGGALYGPNGTITSP 220
F+ C S +G ++ + G+ CA C G+ G C CG L P G I
Sbjct: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR-CGQVLRAPKGQILLE 142
Query: 221 SFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGAD--V 278
S YP +C W I A P I L F LE ++M C+YD V V D +
Sbjct: 143 S----YPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYM----CQYDYVEVRDGDNRDGQI 194
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHE- 337
++R CG P P+ S GS L V F SDGS + GF A+Y ++ C ++ C H+
Sbjct: 195 IKR---VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE-EITAC--SSSPCFHDG 248
Query: 338 -C-HNTLGGYECACHSGFTLHPNKHDCKEGGC 367
C + G Y+CAC +G+T ++ +E C
Sbjct: 249 TCVLDKAGSYKCACLAGYTGQRCENLLEERNC 280
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 344 GYECA-CHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG 402
G+ CA C +G+ DC C + P G I +YP C W PG
Sbjct: 110 GFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILLESYPL----NAHCEWTIHAKPG 159
Query: 403 HRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFK 462
I+L F + LE C YD+V + DG + D + + CG++ P + + + ++++F
Sbjct: 160 FVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFH 219
Query: 463 SDGSVQRKGFLATHS--TAC 480
SDGS GF A + TAC
Sbjct: 220 SDGSKNFDGFHAIYEEITAC 239
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/94 (32%), Positives = 44/94 (46%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIK 562
+Y A C+W I A ++L F+ LE + C+YDYV+V CG +
Sbjct: 143 SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE 202
Query: 563 MPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P I S +L V F +D S F GF A Y+ +
Sbjct: 203 RPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
>BX640988-1|CAE45995.1| 705|Homo sapiens hypothetical protein
protein.
Length = 705
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 67 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 126
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 127 LLLGKIC-NDTGQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 168
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 58 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 116
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 117 EIFDGSLNSSLLLGKIC-NDTGQIFTSSYNRMTIHFRSDISFQNTGFLAWY 166
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 300 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 356
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 357 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 406
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 58 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 113
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 114 DYVEIFDGSLNSSLLL--GKICNDT-GQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 170
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 171 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 226
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 259 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 318
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 319 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 376
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 377 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 406
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 299 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 358
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 359 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 407
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 299 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 352
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 353 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 406
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 5/117 (4%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
S+ CGG+L S+ Y Y + A C W IE + + L F +LE N
Sbjct: 55 SSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHN 110
Query: 537 CRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
C +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 111 CSFDYVEIFDGSLNSSLLLGKICN-DTGQIFTSSYNRMTIHFRSDISFQNTGFLAWY 166
>AL603764-10|CAI14496.1| 2413|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AL603764-9|CAI14495.1| 2413|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AL603764-8|CAI14488.1| 2413|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AL603764-7|CAI14494.1| 2412|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2412
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2007 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2063
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2064 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 64.5 bits (150), Expect = 1e-09
Identities = 43/150 (28%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEGG--CKHDVTLPHGTIFSPNYPAA 386
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNNYSCGGFLSQPSGDFSSPFYPGN 2026
Query: 387 YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKL 446
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 YPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGAR 2084
Query: 447 PHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 GSFT-SSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2006 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2065
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2066 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2114
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2006 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2059
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2060 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AL603764-6|CAI14493.1| 1785|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 1785
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1207 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1138 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1197 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1380 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 1436
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1193
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1194 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1306
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1339 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1398
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 1399 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 1456
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 1457 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 1438
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 1439 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 1487
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1379 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 1432
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 1433 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1132 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1187
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1188 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
>AL603764-5|CAI14492.1| 2403|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2403
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1765 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1824
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1825 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1866
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1756 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1814
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1815 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1864
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1998 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2054
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2055 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1756 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1811
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1812 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1868
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1869 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1924
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1957 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2016
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2017 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2074
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2075 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1997 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2056
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2057 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2105
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1997 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2050
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2051 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1750 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1805
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1806 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1864
>AL603764-4|CAI14491.1| 1785|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 1785
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1207 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1138 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1197 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1380 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 1436
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1193
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1194 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1306
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1339 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1398
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 1399 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 1456
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 1457 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 1438
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 1439 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 1487
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1379 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 1432
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 1433 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1132 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1187
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1188 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
>AL603764-3|CAI14490.1| 1785|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 1785
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1207 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1138 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1197 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1380 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 1436
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1193
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1194 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1306
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1339 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1398
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 1399 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 1456
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 1457 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 1438
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 1439 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 1487
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1379 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 1432
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 1433 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1132 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1187
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1188 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
>AL603764-2|CAI14489.1| 2542|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2542
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1904 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1963
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1964 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 2005
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1895 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1953
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1954 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 2003
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2137 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2194 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2243
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1895 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1950
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1951 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 2007
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 2008 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 2063
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 2096 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2155
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2156 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2213
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2214 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2243
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2136 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2195
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2196 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2244
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2136 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2189
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2190 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2243
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1889 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1944
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1945 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 2003
>AL603764-1|CAI14487.1| 2413|Homo sapiens deleted in malignant brain
tumors 1 protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AK126252-1|BAC86505.1| 386|Homo sapiens protein ( Homo sapiens
cDNA FLJ44264 fis, clone TLIVE2003225, moderately
similar to Homo sapiens CUB and Sushi multiple domains 1
(CSMD1). ).
Length = 386
Score = 85.4 bits (202), Expect = 6e-16
Identities = 81/291 (27%), Positives = 124/291 (42%), Gaps = 46/291 (15%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
NG + SP YPD+Y + C W + VP + + F + E YD + V DG +
Sbjct: 2 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVWDGPDQN 57
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGF--------------------SA 158
SP IG F G+ + STSN++L+ F SD T +GF +A
Sbjct: 58 SPQIGQFSGNTALESVYSTSNQILIKFHSDFTT--SGFFVLSYHAYQLRVCQPPPPVPNA 115
Query: 159 TFMKEFDECASIDHGCSHSCV---NTLGGYECACDIGYELHSDGKK--CENAC--GGALY 211
+ E DE I + C+ +G C +G L DG C+ C
Sbjct: 116 EILTEDDE-FEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRL 174
Query: 212 GPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVH 271
G I SP +P+ YP L+ C W I + IT+ F F +Q E E+D + V+
Sbjct: 175 DSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITM-FVEF-------FQTEKEFDVLQVY 226
Query: 272 S--KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
+ + VL +A +TS+G + +Q+++D ++ GF Y
Sbjct: 227 DGPNIQSPVLISLSGDYSSAF--NITSNGHEVFLQWSADHGNNKKGFRIRY 275
Score = 69.3 bits (162), Expect = 4e-11
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASAD 434
+GTI+SP YP YP +DC W PG+ I + F V + EP YD +T++DG +
Sbjct: 2 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEP----IYDFITVWDGPDQN 57
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+G F G+ V ++ NQ+ + F SD + L+ H+
Sbjct: 58 SPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHA 100
Score = 65.3 bits (152), Expect = 6e-10
Identities = 77/312 (24%), Positives = 124/312 (39%), Gaps = 42/312 (13%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
NGTI SP +P+ YP ++C W + PP + I +NFT + Q E YD +TV
Sbjct: 2 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFT--------VLQTEPIYDFITVWD- 52
Query: 274 LGADVLRRH-GAFCG-TALPPPVTSDGSVL---RVQFTSDG----SVHRSGFAAVY---- 320
G D G F G TAL ++ +L FT+ G S H
Sbjct: 53 -GPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPP 111
Query: 321 -----YIDVDECAENNGGCQHEC---HNTLGGYECACHSGFTLHPNKHD--CKEGGCKHD 370
+ D+ E +++C +G C G L + C+ ++
Sbjct: 112 VPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANE 171
Query: 371 VTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYD 429
+ L G I SP YP +YP + C W S G+ I + F+ E +D + +YD
Sbjct: 172 LRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----FDVLQVYD 227
Query: 430 GASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATE 488
G + L G + ++ +++++ + +D +KGF + Y S E
Sbjct: 228 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRY---IAFYCSTPE 284
Query: 489 EVKHLYSHARYG 500
H Y ++ G
Sbjct: 285 SPPHGYIISQTG 296
Score = 60.5 bits (140), Expect = 2e-08
Identities = 43/173 (24%), Positives = 80/173 (46%), Gaps = 16/173 (9%)
Query: 47 EAVC-GGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCS 105
+ +C ++ +DS G + SP YPD Y ++C W +SV + Y + + F+ E
Sbjct: 164 QVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEK----E 219
Query: 106 YDKVKVRDGDSMDSP-LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEF 164
+D ++V DG ++ SP LI + + +I S +++ + + +D K GF ++ +
Sbjct: 220 FDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFY 279
Query: 165 DECASIDHGCSHSCVNTLGG-----YECACDIGYELHSDGKKCENACGGALYG 212
C++ + ++ GG ACD G+ L K C + YG
Sbjct: 280 --CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVG---KSSAVCRKSSYG 327
Score = 32.7 bits (71), Expect = 4.1
Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 4/78 (5%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y + DC W + P + + + F + E YD++ V+ F G
Sbjct: 14 YPNFQDCFWLVRVPPGNGIYINFTVLQTEPI----YDFITVWDGPDQNSPQIGQFSGNTA 69
Query: 564 PPEIVSTSEALLVRFRTD 581
+ STS +L++F +D
Sbjct: 70 LESVYSTSNQILIKFHSD 87
>AK027841-1|BAB55404.1| 737|Homo sapiens protein ( Homo sapiens
cDNA FLJ14935 fis, clone PLACE1009992, weakly similar to
LIMULUS CLOTTING FACTOR C PRECURSOR (EC 3.4.21.84). ).
Length = 737
Score = 85.4 bits (202), Expect = 6e-16
Identities = 48/137 (35%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Query: 69 DDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGH 128
+ Y N C W + + + LRF +E C YD V+VRDGD+ D +I CG+
Sbjct: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
Query: 129 KIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCV-NTLGGYEC 187
+ P I+S + L V+F SD + GF A + +E C+S +CV + G Y+C
Sbjct: 202 ERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY-EEITACSSSPCFHDGTCVLDKAGPYKC 260
Query: 188 ACDIGYELHSDGKKCEN 204
AC GY G++CEN
Sbjct: 261 ACLAGY----TGQRCEN 273
Score = 78.2 bits (184), Expect = 8e-14
Identities = 67/199 (33%), Positives = 93/199 (46%), Gaps = 27/199 (13%)
Query: 164 FDECASIDHGCSHSCVNT--LGGYECA-CDIGYELHSDGKKCENACGGALYGPNGTITSP 220
F+ C S +G ++ + G+ CA C G+ G C CG L P G I
Sbjct: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR-CGQVLRAPKGQILLE 142
Query: 221 SFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGAD--V 278
S YP +C W I A P I L F LE ++M C+YD V V D +
Sbjct: 143 S----YPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYM----CQYDYVEVRDGDNRDGQI 194
Query: 279 LRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHE- 337
++R CG P P+ S GS L V F SDGS + GF A+Y ++ C ++ C H+
Sbjct: 195 IKR---VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE-EITAC--SSSPCFHDG 248
Query: 338 -C-HNTLGGYECACHSGFT 354
C + G Y+CAC +G+T
Sbjct: 249 TCVLDKAGPYKCACLAGYT 267
Score = 63.3 bits (147), Expect = 3e-09
Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 344 GYECA-CHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPG 402
G+ CA C +G+ DC C + P G I +YP C W PG
Sbjct: 110 GFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILLESYPL----NAHCEWTIHAKPG 159
Query: 403 HRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFK 462
I+L F + LE C YD+V + DG + D + + CG++ P + + + ++++F
Sbjct: 160 FVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFH 219
Query: 463 SDGSVQRKGFLATHS--TAC 480
SDGS GF A + TAC
Sbjct: 220 SDGSKNFDGFHAIYEEITAC 239
Score = 60.1 bits (139), Expect = 2e-08
Identities = 31/94 (32%), Positives = 44/94 (46%)
Query: 503 AYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIK 562
+Y A C+W I A ++L F+ LE + C+YDYV+V CG +
Sbjct: 143 SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE 202
Query: 563 MPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
P I S +L V F +D S F GF A Y+ +
Sbjct: 203 RPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
>AJ297935-1|CAC44122.1| 2413|Homo sapiens DMBT1/8kb.2 protein protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AJ243224-1|CAB63942.1| 2403|Homo sapiens DMBT1/8kb.1 protein protein.
Length = 2403
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1765 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1824
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1825 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1866
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1756 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1814
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1815 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1864
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1998 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2054
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2055 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1756 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1811
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1812 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1868
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1869 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1924
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1957 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2016
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2017 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2074
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2075 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1997 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2056
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2057 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2105
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1997 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2050
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2051 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2104
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1750 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1805
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1806 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1864
>AJ243212-1|CAB56155.1| 2412|Homo sapiens DMBT1/8kb.2 protein protein.
Length = 2412
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2007 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2063
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2064 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 66.9 bits (156), Expect = 2e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGAVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 64.5 bits (150), Expect = 1e-09
Identities = 43/150 (28%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEGG--CKHDVTLPHGTIFSPNYPAA 386
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNNYSCGGFLSQPSGDFSSPFYPGN 2026
Query: 387 YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKL 446
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 YPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGAR 2084
Query: 447 PHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 GSFT-SSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2006 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2065
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2066 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2114
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2006 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2059
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2060 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2113
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AJ243211-1|CAB63941.1| 2426|Homo sapiens DMBT1 prototype protein.
Length = 2426
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1788 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1847
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1848 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1889
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1779 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1837
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1838 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1887
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2021 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2077
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2078 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2127
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1779 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1834
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1835 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1891
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1892 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1947
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1980 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2039
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2040 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2097
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2098 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2127
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2020 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2079
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2080 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2128
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2020 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2073
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2074 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2127
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1773 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1828
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1829 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1887
>AJ000342-1|CAA04019.1| 1785|Homo sapiens DMBT1/6kb.1 protein protein.
Length = 1785
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1207 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1138 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1197 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1380 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 1436
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1193
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1194 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1306
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1339 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1398
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 1399 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 1456
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 1457 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 1438
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 1439 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 1487
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1379 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 1432
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 1433 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1132 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1187
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1188 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
>AF159456-1|AAD49696.1| 2413|Homo sapiens gp-340 variant protein
protein.
Length = 2413
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1775 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1834
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1835 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1766 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1824
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1825 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 2008 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 2064
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 2065 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1766 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1821
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1822 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1878
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1879 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1934
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1967 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 2026
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 2027 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 2084
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 2085 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 2007 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 2066
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 2067 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 2115
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 2007 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 2060
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 2061 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 2114
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1760 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1815
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1816 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1874
>AB020851-1|BAA78577.1| 1785|Homo sapiens DMBT1 protein.
Length = 1785
Score = 85.4 bits (202), Expect = 6e-16
Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADV 435
GT SP+YPA YP CVW+ G+RI L F+ +LE H C++D+V I+DG+
Sbjct: 1147 GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSS 1206
Query: 436 KTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHST 478
LG C + + +S N+M + F+SD S Q GFLA +++
Sbjct: 1207 LLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 74.9 bits (176), Expect = 8e-13
Identities = 38/111 (34%), Positives = 59/111 (53%), Gaps = 2/111 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP+YP Y N C+W++ V Y++ L F + ++E H CS+D V
Sbjct: 1138 CGGFLFYAS-GTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYV 1196
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ DG S L+G C + S+ N++ + F SD + Q GF A +
Sbjct: 1197 EIFDGSLNSSLLLGKIC-NDTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
Score = 70.5 bits (165), Expect = 2e-11
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + S G SP YP +Y N C+W + V +Y+V + F ++E C+YD +
Sbjct: 1380 CGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEG--GCNYDYI 1436
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
+V DG SPLI C S+SN + + F SD ++ + GF A +
Sbjct: 1437 EVFDGPYRSSPLIARVC-DGARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 66.5 bits (155), Expect = 3e-10
Identities = 50/176 (28%), Positives = 77/176 (43%), Gaps = 16/176 (9%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG L+ +GT +SPS+P YP C+WEI +RI L F++ LE +H C +
Sbjct: 1138 CGGFLFYASGTFSSPSYPAYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHH----NCSF 1193
Query: 266 DSVTV-HSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY---- 320
D V + L + +L G C TS + + + F SD S +GF A Y
Sbjct: 1194 DYVEIFDGSLNSSLLL--GKICNDT-RQIFTSSYNRMTIHFRSDISFQNTGFLAWYNSFP 1250
Query: 321 ---YIDVDECAENNGGCQHECHNTLGG-YECACHSGFTLHPNKHDCKEGGCKHDVT 372
+ + + G C GG + C +T+ + C++ GC V+
Sbjct: 1251 SDATLRLVNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVS 1306
Score = 63.7 bits (148), Expect = 2e-09
Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 7/151 (4%)
Query: 330 NNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDCKEG---GCKHDVTLPHGTIFSPNYPA 385
N G H C H G C+ + T P + + C ++ P G SP YP
Sbjct: 1339 NRGWFSHNCNHREDAGVICSGNHLSTPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPG 1398
Query: 386 AYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
YP CVW +R+ +IF +LE C YD++ ++DG + C
Sbjct: 1399 NYPNNAKCVWDIEVQNNYRVTVIFRDVQLE--GGCNYDYIEVFDGPYRSSPLIARVCDGA 1456
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+S N M + F SD S+ R+GF A +
Sbjct: 1457 RGSFT-SSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE 264
+CGG L P+G +SP +P YP C+W+I +R+T+ F LEG Y
Sbjct: 1379 SCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEV 1438
Query: 265 YDSVTVHSKLGADVL-RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
+D S L A V G+F TS + + ++F SD S+ R GF A YY
Sbjct: 1439 FDGPYRSSPLIARVCDGARGSF---------TSSSNFMSIRFISDHSITRRGFRAEYY 1487
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/115 (31%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 479 ACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCR 538
+CGG+LS + +S Y N Y + A C W+IE N+ V + F +L E C
Sbjct: 1379 SCGGFLS---QPSGDFSSPFYPGN-YPNNAKCVWDIEVQNNYRVTVIFRDVQL--EGGCN 1432
Query: 539 YDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
YDY++VF C S+S + +RF +D S+ +GF A Y
Sbjct: 1433 YDYIEVFDGPYRSSPLIARVCD-GARGSFTSSSNFMSIRFISDHSITRRGFRAEY 1486
Score = 53.2 bits (122), Expect = 3e-06
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 5/120 (4%)
Query: 474 ATHSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER 533
A S+ CGG+L S+ Y Y + A C W IE + + L F +LE
Sbjct: 1132 ARPSSNCGGFLFYASGTFSSPSYPAY----YPNNAKCVWEIEVNSGYRINLGFSNLKLEA 1187
Query: 534 EANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
NC +DYV++F C S+ + + FR+D S GF A Y
Sbjct: 1188 HHNCSFDYVEIFDGSLNSSLLLGKICN-DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWY 1246
>BC032109-1|AAH32109.1| 859|Homo sapiens low density
lipoprotein-related protein 12 protein.
Length = 859
Score = 79.4 bits (187), Expect = 4e-14
Identities = 48/140 (34%), Positives = 69/140 (49%), Gaps = 14/140 (10%)
Query: 205 ACGGA---LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
ACG + P+G ITSP +P YP NC W I A P IT++F FD++G+ +
Sbjct: 46 ACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGS----R 101
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C D +T+ + + R CG+ +PPP S + ++F SD ++ R GF Y+
Sbjct: 102 RCNLDWLTIETYKNIESYRA----CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYF 157
Query: 322 IDVDECAENNGGC-QHECHN 340
E E N C Q C N
Sbjct: 158 SGKSE--EPNCACDQFRCGN 175
Score = 69.3 bits (162), Expect = 4e-11
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
G + P G I SP +P+ YPA+ +C W PG I + F F+++ + C D
Sbjct: 48 GETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDW 107
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+TI + + CGS +P ++SQ+ +++ F SD ++ RKGF
Sbjct: 108 LTIETYKNIESYRA---CGSTIPPPYISSQDHIWIRFHSDDNISRKGF 152
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G +C D+G E+ D CG L GT SP++P+ YPP NC W I
Sbjct: 241 GNIDCL-DLGDEIDCDVP----TCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHR 295
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
++ L FT F L+G YD + + +LR AF A P V S +R
Sbjct: 296 KVILRFTDFKLDGTGYGDYVKIYDGLEENPH---KLLRVLTAFDSHA-PLTVVSSSGQIR 351
Query: 303 VQFTSDGSVHRSGFAAVYYID 323
V F +D GF A Y +D
Sbjct: 352 VHFCADKVNAARGFNATYQVD 372
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 361 DCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
DC C + +GT SPNYP YP +C W T ++ L F F+L+
Sbjct: 253 DCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLD---GT 309
Query: 421 AY-DHVTIYDGASADV-KTLGIFCG--SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
Y D+V IYDG + K L + S P V++S Q+ + F +D +GF AT+
Sbjct: 310 GYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATY 369
Score = 54.0 bits (124), Expect = 2e-06
Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
STACG + + + + Y ++ +C W I A + ++F F+++
Sbjct: 44 STACGETPEQIRAPSGIITSPGW-PSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRR 102
Query: 537 CRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
C D++ + CG +PP +S+ + + +RF +DD++ KGF +Y
Sbjct: 103 CNLDWLTIETYKNIESYRA---CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAY 156
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G + SP +P +Y C W + + + F F+++ C+ D + + +++
Sbjct: 58 SGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIE 117
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KEFDECASIDHGCS 175
S CG IPP S+ + + + F SD + + GF + E CA C
Sbjct: 118 S---YRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCG 174
Query: 176 H-SCV 179
+ C+
Sbjct: 175 NGKCI 179
Score = 50.8 bits (116), Expect = 1e-05
Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 9/106 (8%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SPNYPD Y P C W + +V LRF F+++ T D VK+ DG ++
Sbjct: 268 GTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDG--TGYGDYVKIYDG-LEEN 324
Query: 120 P-----LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P ++ F H P + S+S ++ V F +D GF+AT+
Sbjct: 325 PHKLLRVLTAFDSH-APLTVVSSSGQIRVHFCADKVNAARGFNATY 369
Score = 31.9 bits (69), Expect = 7.2
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXX---XXXXXTFCG 560
Y ++C W I+ + V L F F+L+ DYV+++ T
Sbjct: 279 YPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYG--DYVKIYDGLEENPHKLLRVLTAFD 336
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
P +VS+S + V F D +GF+A+YQ+
Sbjct: 337 SHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQV 371
>AF166350-1|AAD44360.1| 859|Homo sapiens ST7 protein protein.
Length = 859
Score = 79.4 bits (187), Expect = 4e-14
Identities = 48/140 (34%), Positives = 69/140 (49%), Gaps = 14/140 (10%)
Query: 205 ACGGA---LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
ACG + P+G ITSP +P YP NC W I A P IT++F FD++G+ +
Sbjct: 46 ACGETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGS----R 101
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYY 321
C D +T+ + + R CG+ +PPP S + ++F SD ++ R GF Y+
Sbjct: 102 RCNLDWLTIETYKNIESYRA----CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYF 157
Query: 322 IDVDECAENNGGC-QHECHN 340
E E N C Q C N
Sbjct: 158 SGKSE--EPNCACDQFRCGN 175
Score = 69.3 bits (162), Expect = 4e-11
Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
G + P G I SP +P+ YPA+ +C W PG I + F F+++ + C D
Sbjct: 48 GETPEQIRAPSGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDW 107
Query: 425 VTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+TI + + CGS +P ++SQ+ +++ F SD ++ RKGF
Sbjct: 108 LTIETYKNIESYRA---CGSTIPPPYISSQDHIWIRFHSDDNISRKGF 152
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G +C D+G E+ D CG L GT SP++P+ YPP NC W I
Sbjct: 241 GNIDCL-DLGDEIDCDVP----TCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHR 295
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
++ L FT F L+G YD + + +LR AF A P V S +R
Sbjct: 296 KVILRFTDFKLDGTGYGDYVKIYDGLEENPH---KLLRVLTAFDSHA-PLTVVSSSGQIR 351
Query: 303 VQFTSDGSVHRSGFAAVYYID 323
V F +D GF A Y +D
Sbjct: 352 VHFCADKVNAARGFNATYQVD 372
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 361 DCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
DC C + +GT SPNYP YP +C W T ++ L F F+L+
Sbjct: 253 DCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLD---GT 309
Query: 421 AY-DHVTIYDGASADV-KTLGIFCG--SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
Y D+V IYDG + K L + S P V++S Q+ + F +D +GF AT+
Sbjct: 310 GYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATY 369
Score = 54.0 bits (124), Expect = 2e-06
Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREAN 536
STACG + + + + Y ++ +C W I A + ++F F+++
Sbjct: 44 STACGETPEQIRAPSGIITSPGW-PSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRR 102
Query: 537 CRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
C D++ + CG +PP +S+ + + +RF +DD++ KGF +Y
Sbjct: 103 CNLDWLTIETYKNIESYRA---CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAY 156
Score = 50.8 bits (116), Expect = 1e-05
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G + SP +P +Y C W + + + F F+++ C+ D + + +++
Sbjct: 58 SGIITSPGWPSEYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIE 117
Query: 119 SPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KEFDECASIDHGCS 175
S CG IPP S+ + + + F SD + + GF + E CA C
Sbjct: 118 S---YRACGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCG 174
Query: 176 H-SCV 179
+ C+
Sbjct: 175 NGKCI 179
Score = 50.8 bits (116), Expect = 1e-05
Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 9/106 (8%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SPNYPD Y P C W + +V LRF F+++ T D VK+ DG ++
Sbjct: 268 GTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDG--TGYGDYVKIYDG-LEEN 324
Query: 120 P-----LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P ++ F H P + S+S ++ V F +D GF+AT+
Sbjct: 325 PHKLLRVLTAFDSH-APLTVVSSSGQIRVHFCADKVNAARGFNATY 369
Score = 31.9 bits (69), Expect = 7.2
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXX---XXXXXTFCG 560
Y ++C W I+ + V L F F+L+ DYV+++ T
Sbjct: 279 YPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYG--DYVKIYDGLEENPHKLLRVLTAFD 336
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
P +VS+S + V F D +GF+A+YQ+
Sbjct: 337 SHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQV 371
>AF448839-1|AAM18027.1| 156|Homo sapiens neuropilin and tolloid
like-1 protein.
Length = 156
Score = 78.6 bits (185), Expect = 6e-14
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 1/112 (0%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF-HSFEVENHDTCSYDK 108
CG + G SPNYP Y P++ CI+ + + L F + +E C +D
Sbjct: 40 CGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDH 99
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++VRDG SP+IG FCG + PP I+S+ L + F +D ++ GFSA +
Sbjct: 100 IEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151
Score = 77.0 bits (181), Expect = 2e-13
Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 1/103 (0%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNV-FELEPHQECAYDHVTIYDGASAD 434
G SPNYP+ YP ++C++ P I+L F+ + +EP EC +DH+ + DG
Sbjct: 50 GIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGF 109
Query: 435 VKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+G FCG + P ++ +S +++ F +DG ++ GF A ++
Sbjct: 110 SPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYN 152
Score = 65.3 bits (152), Expect = 6e-10
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 6/111 (5%)
Query: 211 YGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTV 270
+ G TSP++P YPP + C++ I A P+ I L +FD + + EC++D + V
Sbjct: 46 HAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIEL---YFDEKYSIEPSWECKFDHIEV 102
Query: 271 HS-KLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
G + G FCG PP + S G L ++F +DG + GF+A Y
Sbjct: 103 RDGPFGFSPII--GRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151
Score = 48.4 bits (110), Expect = 8e-05
Identities = 32/118 (27%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 477 STACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTF-LTFELEREA 535
S CG + E +++ Y + Y +C + IEA ++L F + +E
Sbjct: 37 SVQCGTWTKHAEG--GIFTSPNY-PSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSW 93
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
C++D+++V FCG + PP I S+ L ++F D L GFSA Y
Sbjct: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARY 151
>D29810-1|BAA18909.1| 364|Homo sapiens unknown protein.
Length = 364
Score = 78.2 bits (184), Expect = 8e-14
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 3/115 (2%)
Query: 366 GCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GC H V P GT+ S NYP YP C W+ G R+++ F F++E C +++
Sbjct: 2 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 61
Query: 425 VTIYDGASADVKTLGIFC--GSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+ IY+G +G +C G ++ H + + N++ ++F S V +GFLA++S
Sbjct: 62 LRIYNGIGVSRTEIGKYCGLGLQINHSIESKGNEITLLFMSGIHVSGRGFLASYS 116
Score = 68.9 bits (161), Expect = 5e-11
Identities = 33/113 (29%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CG + +G L S NYP Y + +C W++ V +V ++F F++E+ D+C ++ +
Sbjct: 3 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 62
Query: 110 KVRDGDSMDSPLIGMFC--GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ +G + IG +C G +I I S N++ ++F S V GF A++
Sbjct: 63 RIYNGIGVSRTEIGKYCGLGLQINHSIESKGNEITLLFMSGIHVSGRGFLASY 115
Score = 58.8 bits (136), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 9/130 (6%)
Query: 204 NACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQE 262
+ CG + GP +GT+TS ++P+ YP C WEI R+ + F FD+E +
Sbjct: 1 DGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDS----DS 56
Query: 263 CEYDSVTVHSKLGADVLRRHGAFCGTALP--PPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C ++ + +++ +G G +CG L + S G+ + + F S V GF A Y
Sbjct: 57 CHFNYLRIYNGIGVS-RTEIGKYCGLGLQINHSIESKGNEITLLFMSGIHVSGRGFLASY 115
Query: 321 YIDVDECAEN 330
+ +D+ N
Sbjct: 116 SV-IDKQRSN 124
Score = 44.0 bits (99), Expect = 0.002
Identities = 20/95 (21%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--GI 561
Y + C+W I V++ F F++E +C ++Y++++ +C G+
Sbjct: 24 YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGL 83
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
++ I S + + F + + +GF ASY ++
Sbjct: 84 QINHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 118
>BC029658-1|AAH29658.1| 743|Homo sapiens DCBLD2 protein protein.
Length = 743
Score = 78.2 bits (184), Expect = 8e-14
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 3/115 (2%)
Query: 366 GCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GC H V P GT+ S NYP YP C W+ G R+++ F F++E C +++
Sbjct: 25 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 84
Query: 425 VTIYDGASADVKTLGIFC--GSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+ IY+G +G +C G ++ H + + N++ ++F S V +GFLA++S
Sbjct: 85 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYS 139
Score = 67.7 bits (158), Expect = 1e-10
Identities = 32/113 (28%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CG + +G L S NYP Y + +C W++ V +V ++F F++E+ D+C ++ +
Sbjct: 26 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 85
Query: 110 KVRDGDSMDSPLIGMFC--GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ +G + IG +C G ++ I S N++ ++F S V GF A++
Sbjct: 86 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 138
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 8/131 (6%)
Query: 195 LHSDGKKCENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDL 253
L G + + CG + GP +GT+TS ++P+ YP C WEI R+ + F FD+
Sbjct: 15 LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI 74
Query: 254 EGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALP--PPVTSDGSVLRVQFTSDGSV 311
E + C ++ + +++ +G G +CG L + S G+ + + F S V
Sbjct: 75 EDS----DSCHFNYLRIYNGIGVS-RTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHV 129
Query: 312 HRSGFAAVYYI 322
GF A Y +
Sbjct: 130 SGRGFLASYSV 140
Score = 45.6 bits (103), Expect = 5e-04
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--GI 561
Y + C+W I V++ F F++E +C ++Y++++ +C G+
Sbjct: 47 YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGL 106
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+M I S + + F + + +GF ASY ++
Sbjct: 107 QMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 141
>AF387547-1|AAL30178.1| 775|Homo sapiens endothelial and smooth
muscle cell-derived neuropilin-like protein protein.
Length = 775
Score = 78.2 bits (184), Expect = 8e-14
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 3/115 (2%)
Query: 366 GCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GC H V P GT+ S NYP YP C W+ G R+++ F F++E C +++
Sbjct: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
Query: 425 VTIYDGASADVKTLGIFC--GSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+ IY+G +G +C G ++ H + + N++ ++F S V +GFLA++S
Sbjct: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYS 185
Score = 67.7 bits (158), Expect = 1e-10
Identities = 32/113 (28%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CG + +G L S NYP Y + +C W++ V +V ++F F++E+ D+C ++ +
Sbjct: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
Query: 110 KVRDGDSMDSPLIGMFC--GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ +G + IG +C G ++ I S N++ ++F S V GF A++
Sbjct: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 8/131 (6%)
Query: 195 LHSDGKKCENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDL 253
L G + + CG + GP +GT+TS ++P+ YP C WEI R+ + F FD+
Sbjct: 61 LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI 120
Query: 254 EGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALP--PPVTSDGSVLRVQFTSDGSV 311
E + C ++ + +++ +G G +CG L + S G+ + + F S V
Sbjct: 121 EDS----DSCHFNYLRIYNGIGVS-RTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHV 175
Query: 312 HRSGFAAVYYI 322
GF A Y +
Sbjct: 176 SGRGFLASYSV 186
Score = 45.6 bits (103), Expect = 5e-04
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--GI 561
Y + C+W I V++ F F++E +C ++Y++++ +C G+
Sbjct: 93 YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGL 152
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+M I S + + F + + +GF ASY ++
Sbjct: 153 QMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 187
>AB073146-1|BAB91138.1| 775|Homo sapiens CLCP1 protein.
Length = 775
Score = 78.2 bits (184), Expect = 8e-14
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 3/115 (2%)
Query: 366 GCKHDVTLPH-GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDH 424
GC H V P GT+ S NYP YP C W+ G R+++ F F++E C +++
Sbjct: 71 GCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNY 130
Query: 425 VTIYDGASADVKTLGIFC--GSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHS 477
+ IY+G +G +C G ++ H + + N++ ++F S V +GFLA++S
Sbjct: 131 LRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYS 185
Score = 67.7 bits (158), Expect = 1e-10
Identities = 32/113 (28%), Positives = 61/113 (53%), Gaps = 2/113 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CG + +G L S NYP Y + +C W++ V +V ++F F++E+ D+C ++ +
Sbjct: 72 CGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYL 131
Query: 110 KVRDGDSMDSPLIGMFC--GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
++ +G + IG +C G ++ I S N++ ++F S V GF A++
Sbjct: 132 RIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASY 184
Score = 59.7 bits (138), Expect = 3e-08
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 8/131 (6%)
Query: 195 LHSDGKKCENACGGALYGP-NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDL 253
L G + + CG + GP +GT+TS ++P+ YP C WEI R+ + F FD+
Sbjct: 61 LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI 120
Query: 254 EGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALP--PPVTSDGSVLRVQFTSDGSV 311
E + C ++ + +++ +G G +CG L + S G+ + + F S V
Sbjct: 121 EDS----DSCHFNYLRIYNGIGVS-RTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHV 175
Query: 312 HRSGFAAVYYI 322
GF A Y +
Sbjct: 176 SGRGFLASYSV 186
Score = 45.6 bits (103), Expect = 5e-04
Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC--GI 561
Y + C+W I V++ F F++E +C ++Y++++ +C G+
Sbjct: 93 YPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGL 152
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQMV 596
+M I S + + F + + +GF ASY ++
Sbjct: 153 QMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVI 187
>M31165-1|AAB00792.1| 277|Homo sapiens adhesion receptor CD44
protein.
Length = 277
Score = 77.4 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + D +SP +P++Y+ N++C W + + ++ L F F++E+ C D V
Sbjct: 135 CGG-VFTDPKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECAS 169
++ D +G +CG ++P DI ST N + + F SD++V GF ++ D +
Sbjct: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSK 252
Query: 170 IDHGCSHSCVNT 181
G + S +T
Sbjct: 253 SSQGKNTSTTST 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 476 HSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA 535
H+ CGG + + K ++ + N YE C W+I + L+FL F+LE +
Sbjct: 131 HAKECGGVFT---DPKRIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C DYV+++ +CG ++P +I+ST + ++F +D S+ GF Y
Sbjct: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246
Query: 596 VKP 598
+ P
Sbjct: 247 MDP 249
Score = 70.5 bits (165), Expect = 2e-11
Identities = 43/128 (33%), Positives = 61/128 (47%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P SP FP Y + C W I RI L+F FDLE + C
Sbjct: 135 CGGVFTDPKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD----PGCLA 190
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V ++ DV G +CG LP + S G+V+ ++F SD SV GF + Y+ +D
Sbjct: 191 DYVEIYDSYD-DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF-QIKYVAMD 248
Query: 326 ECAENNGG 333
++++ G
Sbjct: 249 PVSKSSQG 256
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 353 FTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVF 412
+ +P+ +C GG D P SP +P Y + C W G RI L F F
Sbjct: 126 YCYNPHAKEC--GGVFTD---PKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180
Query: 413 ELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+LE C D+V IYD +G +CG +LP ++++ N M + F SD SV GF
Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240
>BC030645-1|AAH30645.1| 364|Homo sapiens platelet derived growth
factor D protein.
Length = 364
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 169
Query: 167 CAS 169
A+
Sbjct: 170 AAA 172
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 65 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 124
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 125 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 112
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 113 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 161
>BC030205-1|AAH30205.1| 277|Homo sapiens tumor necrosis factor,
alpha-induced protein 6 protein.
Length = 277
Score = 77.4 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + D +SP +P++Y+ N++C W + + ++ L F F++E+ C D V
Sbjct: 135 CGG-VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECAS 169
++ D +G +CG ++P DI ST N + + F SD++V GF ++ D +
Sbjct: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSK 252
Query: 170 IDHGCSHSCVNT 181
G + S +T
Sbjct: 253 SSQGKNTSTTST 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 476 HSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA 535
H+ CGG + + K ++ + N YE C W+I + L+FL F+LE +
Sbjct: 131 HAKECGGVFT---DPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C DYV+++ +CG ++P +I+ST + ++F +D S+ GF Y
Sbjct: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246
Query: 596 VKP 598
+ P
Sbjct: 247 MDP 249
Score = 70.5 bits (165), Expect = 2e-11
Identities = 43/128 (33%), Positives = 61/128 (47%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P SP FP Y + C W I RI L+F FDLE + C
Sbjct: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD----PGCLA 190
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V ++ DV G +CG LP + S G+V+ ++F SD SV GF + Y+ +D
Sbjct: 191 DYVEIYDSYD-DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF-QIKYVAMD 248
Query: 326 ECAENNGG 333
++++ G
Sbjct: 249 PVSKSSQG 256
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 353 FTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVF 412
+ +P+ +C GG D P SP +P Y + C W G RI L F F
Sbjct: 126 YCYNPHAKEC--GGVFTD---PKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180
Query: 413 ELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+LE C D+V IYD +G +CG +LP ++++ N M + F SD SV GF
Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240
>AY359116-1|AAQ89474.1| 364|Homo sapiens SCDGF-B protein.
Length = 364
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 169
Query: 167 CAS 169
A+
Sbjct: 170 AAA 172
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 65 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 124
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 125 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 112
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 113 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 161
>AY027518-1|AAK20082.1| 364|Homo sapiens iris-expressed growth
factor short form protein.
Length = 364
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 50 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 109
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 110 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 169
Query: 167 CAS 169
A+
Sbjct: 170 AAA 172
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 114
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 115 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 162
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 65 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 124
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 125 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 165
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 55 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 112
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 113 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 161
>AY027517-1|AAK20081.1| 370|Homo sapiens iris-expressed growth
factor long form protein.
Length = 370
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 56 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 115
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 116 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 175
Query: 167 CAS 169
A+
Sbjct: 176 AAA 178
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 120
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 121 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 168
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 71 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 130
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 131 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 171
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 118
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 119 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 167
>AK092062-1|BAC03798.1| 880|Homo sapiens protein ( Homo sapiens
cDNA FLJ34743 fis, clone MESAN2009019, moderately
similar to CEGP1 protein. ).
Length = 880
Score = 77.4 bits (182), Expect = 1e-13
Identities = 62/217 (28%), Positives = 94/217 (43%), Gaps = 27/217 (12%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPEL 225
C + +HGC+H C T GG C C G+EL + + C+ C YG G + E
Sbjct: 32 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN---YGNGGCQHTCDDTEQ 88
Query: 226 YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAF 285
P C + V + + + H+ Q ++ V++ G D + H A
Sbjct: 89 GPRC-GCHIKFVLHTDGKTCIGERRLE---QHIPTQAVSNETCAVNNG-GCDS-KCHDAA 142
Query: 286 CGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGY 345
G PV G +L+ D + D+DEC NNGGC H C NT+G +
Sbjct: 143 TGVHCTCPV---GFMLQ----PDRKTCK---------DIDECRLNNGGCDHICRNTVGSF 186
Query: 346 ECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
EC+C G+ L N+ +C++ C D T H + +P
Sbjct: 187 ECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTP 223
Score = 52.4 bits (120), Expect = 5e-06
Identities = 23/43 (53%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSG-FTLHPNKHDCKE 364
DVDEC+ N GGC+ C NT G Y+C C +G LH N DC E
Sbjct: 244 DVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTE 286
Score = 52.0 bits (119), Expect = 6e-06
Identities = 31/129 (24%), Positives = 54/129 (41%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
CK C ++ G I SPNYP YPA +C+W + P +I ++ L EC
Sbjct: 686 CKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG 745
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
V + + + + T + P A ++++ FK+ + +GF + T
Sbjct: 746 DVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDE 805
Query: 482 GYLSATEEV 490
Y E++
Sbjct: 806 DYEQLVEDI 814
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G++ESPNYP +Y CIW ++ P ++ + + + D C D +
Sbjct: 691 CGGELG-EFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG-DVL 748
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P + S KL + F++ GF ++ +DE
Sbjct: 749 VMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYV-TYDE 805
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + GC H C NT+G +EC+C GY+L + + C++
Sbjct: 163 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 205
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGKKC 202
+ T + DEC+ GC C+NT G Y+C C G LH +GK C
Sbjct: 237 YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDC 284
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH-----SDGKKCENACGGALYG 212
++ DEC S D C H CVNT G ++C C GY L+ D +C GG +G
Sbjct: 204 QDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG 258
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 8/53 (15%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCK 368
D+DEC+ + C H C NT G ++C CH G+ L+ H +C GGC+
Sbjct: 205 DIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCR 256
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITL 246
+C+N CGG L G I SP++P YP C+W I PP+ +I +
Sbjct: 685 QCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILI 731
Score = 36.3 bits (80), Expect = 0.33
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC C + G C C +G+ L D K C++
Sbjct: 125 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKD 164
Score = 32.7 bits (71), Expect = 4.1
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 342 LGGYECACHSGFTLHPNKHDC 362
+G YEC C GF L N+H C
Sbjct: 2 MGSYECHCREGFFLSDNQHTC 22
>AJ421518-1|CAD13434.1| 277|Homo sapiens TSG-6 protein protein.
Length = 277
Score = 77.4 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + D +SP +P++Y+ N++C W + + ++ L F F++E+ C D V
Sbjct: 135 CGG-VFTDPKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECAS 169
++ D +G +CG ++P DI ST N + + F SD++V GF ++ D +
Sbjct: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSK 252
Query: 170 IDHGCSHSCVNT 181
G + S +T
Sbjct: 253 SSQGKNTSTTST 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 476 HSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA 535
H+ CGG + + K ++ + N YE C W+I + L+FL F+LE +
Sbjct: 131 HAKECGGVFT---DPKRIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C DYV+++ +CG ++P +I+ST + ++F +D S+ GF Y
Sbjct: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246
Query: 596 VKP 598
+ P
Sbjct: 247 MDP 249
Score = 70.5 bits (165), Expect = 2e-11
Identities = 43/128 (33%), Positives = 61/128 (47%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P SP FP Y + C W I RI L+F FDLE + C
Sbjct: 135 CGGVFTDPKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD----PGCLA 190
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V ++ DV G +CG LP + S G+V+ ++F SD SV GF + Y+ +D
Sbjct: 191 DYVEIYDSYD-DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF-QIKYVAMD 248
Query: 326 ECAENNGG 333
++++ G
Sbjct: 249 PVSKSSQG 256
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 353 FTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVF 412
+ +P+ +C GG D P SP +P Y + C W G RI L F F
Sbjct: 126 YCYNPHAKEC--GGVFTD---PKRIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180
Query: 413 ELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+LE C D+V IYD +G +CG +LP ++++ N M + F SD SV GF
Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240
>AJ419936-1|CAD12353.1| 277|Homo sapiens TSG-6 protein protein.
Length = 277
Score = 77.4 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + D +SP +P++Y+ N++C W + + ++ L F F++E+ C D V
Sbjct: 135 CGG-VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECAS 169
++ D +G +CG ++P DI ST N + + F SD++V GF ++ D +
Sbjct: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSK 252
Query: 170 IDHGCSHSCVNT 181
G + S +T
Sbjct: 253 SSQGKNTSTTST 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 476 HSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA 535
H+ CGG + + K ++ + N YE C W+I + L+FL F+LE +
Sbjct: 131 HAKECGGVFT---DPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C DYV+++ +CG ++P +I+ST + ++F +D S+ GF Y
Sbjct: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246
Query: 596 VKP 598
+ P
Sbjct: 247 MDP 249
Score = 70.5 bits (165), Expect = 2e-11
Identities = 43/128 (33%), Positives = 61/128 (47%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P SP FP Y + C W I RI L+F FDLE + C
Sbjct: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD----PGCLA 190
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V ++ DV G +CG LP + S G+V+ ++F SD SV GF + Y+ +D
Sbjct: 191 DYVEIYDSYD-DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF-QIKYVAMD 248
Query: 326 ECAENNGG 333
++++ G
Sbjct: 249 PVSKSSQG 256
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 353 FTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVF 412
+ +P+ +C GG D P SP +P Y + C W G RI L F F
Sbjct: 126 YCYNPHAKEC--GGVFTD---PKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180
Query: 413 ELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+LE C D+V IYD +G +CG +LP ++++ N M + F SD SV GF
Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240
>AF336376-1|AAK56136.1| 370|Homo sapiens platelet-derived growth
factor D protein.
Length = 370
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 56 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 115
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 116 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 175
Query: 167 CAS 169
A+
Sbjct: 176 AAA 178
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 120
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 121 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 168
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 71 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 130
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 131 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 171
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 118
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 119 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 167
>AF335584-1|AAK38840.1| 370|Homo sapiens platelet-derived growth
factor D protein.
Length = 370
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 56 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 115
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 116 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 175
Query: 167 CAS 169
A+
Sbjct: 176 AAA 178
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 120
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 121 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 168
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 71 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 130
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 131 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 171
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 118
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 119 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 167
>AC009311-2|AAY15067.1| 277|Homo sapiens unknown protein.
Length = 277
Score = 77.4 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 68/132 (51%), Gaps = 2/132 (1%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + D +SP +P++Y+ N++C W + + ++ L F F++E+ C D V
Sbjct: 135 CGG-VFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDPGCLADYV 193
Query: 110 KVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECAS 169
++ D +G +CG ++P DI ST N + + F SD++V GF ++ D +
Sbjct: 194 EIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYV-AMDPVSK 252
Query: 170 IDHGCSHSCVNT 181
G + S +T
Sbjct: 253 SSQGKNTSTTST 264
Score = 71.3 bits (167), Expect = 1e-11
Identities = 34/123 (27%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 476 HSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREA 535
H+ CGG + + K ++ + N YE C W+I + L+FL F+LE +
Sbjct: 131 HAKECGGVFT---DPKQIFKSPGF-PNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDDP 186
Query: 536 NCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
C DYV+++ +CG ++P +I+ST + ++F +D S+ GF Y
Sbjct: 187 GCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGFQIKYVA 246
Query: 596 VKP 598
+ P
Sbjct: 247 MDP 249
Score = 70.5 bits (165), Expect = 2e-11
Identities = 43/128 (33%), Positives = 61/128 (47%), Gaps = 6/128 (4%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
CGG P SP FP Y + C W I RI L+F FDLE + C
Sbjct: 135 CGGVFTDPKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDFDLEDD----PGCLA 190
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD 325
D V ++ DV G +CG LP + S G+V+ ++F SD SV GF + Y+ +D
Sbjct: 191 DYVEIYDSYD-DVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF-QIKYVAMD 248
Query: 326 ECAENNGG 333
++++ G
Sbjct: 249 PVSKSSQG 256
Score = 66.1 bits (154), Expect = 4e-10
Identities = 40/120 (33%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 353 FTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVF 412
+ +P+ +C GG D P SP +P Y + C W G RI L F F
Sbjct: 126 YCYNPHAKEC--GGVFTD---PKQIFKSPGFPNEYEDNQICYWHIRLKYGQRIHLSFLDF 180
Query: 413 ELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
+LE C D+V IYD +G +CG +LP ++++ N M + F SD SV GF
Sbjct: 181 DLEDDPGCLADYVEIYDSYDDVHGFVGRYCGDELPDDIISTGNVMTLKFLSDASVTAGGF 240
>AB033832-1|BAB18903.1| 370|Homo sapiens spinal cord-derived growth
factor-B protein.
Length = 370
Score = 77.4 bits (182), Expect = 1e-13
Identities = 41/123 (33%), Positives = 70/123 (56%), Gaps = 7/123 (5%)
Query: 54 IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS---FEVENHDTCSYDKVK 110
I+V NG+++SP +P+ Y N L W+L ++ ++ L F + E +D C YD V+
Sbjct: 56 IQVKGNGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVE 115
Query: 111 VRDGDSMDSPLIGMFCGHK-IPPDIRSTSNKLLVIFESDS-TVQKAGFSA--TFMKEFDE 166
V D + + G +CGHK +PP I+S +N++ + F+SD V K GF + +++F
Sbjct: 116 VEDISETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLEDFQP 175
Query: 167 CAS 169
A+
Sbjct: 176 AAA 178
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 375 HGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIF-NVFELEPHQE--CAYDHVTIYDGA 431
+G + SP +P +YP W+ + RI+L+F N F LE + C YD V + D +
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDIS 120
Query: 432 SADVKTLGIFCGSK-LPHLVMASQNQMYMVFKSDG-SVQRKGFLATHS 477
G +CG K +P + + NQ+ + FKSD V + GF +S
Sbjct: 121 ETSTIIRGRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYS 168
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 5/101 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLT-FELEREAN--CRYDYVQVFXXXXXXXXXXXTF 558
N+Y W + + N ++L F F LE N CRYD+V+V +
Sbjct: 71 NSYPRNLLLTWRLHSQENTRIQLVFDNQFGLEEAENDICRYDFVEVEDISETSTIIRGRW 130
Query: 559 CGIK-MPPEIVSTSEALLVRFRTDDSLVFK-GFSASYQMVK 597
CG K +PP I S + + + F++DD V K GF Y +++
Sbjct: 131 CGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGFKIYYSLLE 171
Score = 45.6 bits (103), Expect = 5e-04
Identities = 36/111 (32%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNF-THFDLEGNHMYQQECEYDSVTVHS 272
NG + SP FP YP W + + RI L F F LE C YD V V
Sbjct: 61 NGYVQSPRFPNSYPRNLLLTWRLHSQENTRIQLVFDNQFGLE--EAENDICRYDFVEVED 118
Query: 273 KLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDG-SVHRSGFAAVYY 321
+ R G +CG +PP + S + +++ F SD V + GF +YY
Sbjct: 119 ISETSTIIR-GRWCGHKEVPPRIKSRTNQIKITFKSDDYFVAKPGF-KIYY 167
>AF057145-1|AAG15395.1| 855|Homo sapiens serine protease TADG15
protein.
Length = 855
Score = 77.0 bits (181), Expect = 2e-13
Identities = 64/228 (28%), Positives = 94/228 (41%), Gaps = 27/228 (11%)
Query: 380 SPNYP-AAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKT 437
+P +P + YPA C W + L F F+L E D VT+Y+ S +
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 438 LGIFCGSKLPHLVM---ASQNQMYMVFKSDGSVQRKGFLAT-----HSTACGGYLSATEE 489
L CG+ P + +SQN + + ++ + GF AT ++CGG L +
Sbjct: 290 LVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQG 349
Query: 490 VKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER----EANCRYDYVQVF 545
++ Y Y DC WNIE P N VK++F F L C DYV++
Sbjct: 350 T----FNSPYYPGHYPPNIDCTWNIEVPNNQHVKVSFKFFYLLEPGVPAGTCPKDYVEI- 404
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + + S S + VRF +D S GF A Y
Sbjct: 405 --------NGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 16/154 (10%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
++CGG L GT SP +P YPP +C W I P + ++F F L + C
Sbjct: 338 SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVSFKFFYLLEPGVPAGTC 397
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY--Y 321
D V ++ + +CG VTS+ + + V+F SD S +GF A Y Y
Sbjct: 398 PKDYVEINGE----------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSY 447
Query: 322 IDVDECAE----NNGGCQHECHNTLGGYECACHS 351
D C G C + G +C HS
Sbjct: 448 DSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHS 481
Score = 58.0 bits (134), Expect = 1e-07
Identities = 51/189 (26%), Positives = 78/189 (41%), Gaps = 34/189 (17%)
Query: 39 HRGFRA-FYE----AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF 93
H GF A F++ + CGG + + G SP YP Y PN C W + VP + V + F
Sbjct: 324 HPGFEATFFQLPRMSSCGGRLR-KAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVSF 382
Query: 94 HSFEVEN----HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
F + TC D V++ +G+ +CG + + S SNK+ V F SD
Sbjct: 383 KFFYLLEPGVPAGTCPKDYVEI-NGEK--------YCGERSQFVVTSNSNKITVRFHSDQ 433
Query: 150 TVQKAGFSATFMK---------EF----DECASIDHGCS--HSCVNTLGGYECACDIGYE 194
+ GF A ++ +F C + C C + C+CD G++
Sbjct: 434 SYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQ 493
Query: 195 LHSDGKKCE 203
K C+
Sbjct: 494 FTCKNKFCK 502
Score = 50.4 bits (115), Expect = 2e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFEL----EPHQECAYDHVTIYDGA 431
GT SP YP YP DC W +K+ F F L P C D+V I +G
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVSFKFFYLLEPGVPAGTCPKDYVEI-NGE 407
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+CG + +V ++ N++ + F SD S GFLA +
Sbjct: 408 K--------YCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 64 SPNYPDD-YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS-MDSPL 121
+P +PD Y + C W L D ++L F SF++ + D D V V + S M+
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 122 IGMFCGHKIPPD----IRSTSNKLLVIFESDSTVQKAGFSATFMK 162
+ CG PP S+ N LL+ +++ + GF ATF +
Sbjct: 290 LVQLCG-TYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQ 333
Score = 34.7 bits (76), Expect = 1.0
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 203 ENACGGALYGPNGTI---TSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHM 258
+N+C L+ + T+P FP+ YP C W + ++L F FDL
Sbjct: 211 DNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLAS--- 267
Query: 259 YQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT----SDGSVLRVQFTSDGSVHRS 314
E D VTV++ L CGT PP S +VL + ++
Sbjct: 268 -CDERGSDLVTVYNTLSPMEPHALVQLCGT-YPPSYNLTFHSSQNVLLITLITNTERRHP 325
Query: 315 GFAAVYY 321
GF A ++
Sbjct: 326 GFEATFF 332
Score = 31.5 bits (68), Expect = 9.5
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 4/123 (3%)
Query: 475 THSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELERE 534
T +C L A ++ + D+ Y + A C W + + + LTF +F+L
Sbjct: 209 TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASC 268
Query: 535 ANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFS 590
D V V+ CG P S+ LL+ T+ GF
Sbjct: 269 DERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFE 328
Query: 591 ASY 593
A++
Sbjct: 329 ATF 331
>BC030532-1|AAH30532.1| 855|Homo sapiens suppression of
tumorigenicity 14 (colon carcinoma) protein.
Length = 855
Score = 76.2 bits (179), Expect = 3e-13
Identities = 64/228 (28%), Positives = 93/228 (40%), Gaps = 27/228 (11%)
Query: 380 SPNYP-AAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKT 437
+P +P + YPA C W + L F F+L E D VT+Y+ S +
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 438 LGIFCGSKLPHLVM---ASQNQMYMVFKSDGSVQRKGFLAT-----HSTACGGYLSATEE 489
L CG+ P + +SQN + + ++ + GF AT ++CGG L +
Sbjct: 290 LVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQG 349
Query: 490 VKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER----EANCRYDYVQVF 545
++ Y Y DC WNIE P N VK+ F F L C DYV++
Sbjct: 350 T----FNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI- 404
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + + S S + VRF +D S GF A Y
Sbjct: 405 --------NGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 34/189 (17%)
Query: 39 HRGFRA-FYE----AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF 93
H GF A F++ + CGG + + G SP YP Y PN C W + VP + V +RF
Sbjct: 324 HPGFEATFFQLPRMSSCGGRLR-KAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRF 382
Query: 94 HSFEVEN----HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
F + TC D V++ +G+ +CG + + S SNK+ V F SD
Sbjct: 383 KFFYLLEPGVPAGTCPKDYVEI-NGEK--------YCGERSQFVVTSNSNKITVRFHSDQ 433
Query: 150 TVQKAGFSATFMK---------EF----DECASIDHGCS--HSCVNTLGGYECACDIGYE 194
+ GF A ++ +F C + C C + C+CD G++
Sbjct: 434 SYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQ 493
Query: 195 LHSDGKKCE 203
K C+
Sbjct: 494 FTCKNKFCK 502
Score = 59.3 bits (137), Expect = 4e-08
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 16/154 (10%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
++CGG L GT SP +P YPP +C W I P + + F F L + C
Sbjct: 338 SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTC 397
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY--Y 321
D V ++ + +CG VTS+ + + V+F SD S +GF A Y Y
Sbjct: 398 PKDYVEINGE----------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSY 447
Query: 322 IDVDECAE----NNGGCQHECHNTLGGYECACHS 351
D C G C + G +C HS
Sbjct: 448 DSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHS 481
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFEL----EPHQECAYDHVTIYDGA 431
GT SP YP YP DC W +K+ F F L P C D+V I +G
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI-NGE 407
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+CG + +V ++ N++ + F SD S GFLA +
Sbjct: 408 K--------YCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 64 SPNYPDD-YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS-MDSPL 121
+P +PD Y + C W L D ++L F SF++ + D D V V + S M+
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 122 IGMFCGHKIPPD----IRSTSNKLLVIFESDSTVQKAGFSATFMK 162
+ CG PP S+ N LL+ +++ + GF ATF +
Sbjct: 290 LVQLCG-TYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQ 333
Score = 34.7 bits (76), Expect = 1.0
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 203 ENACGGALYGPNGTI---TSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHM 258
+N+C L+ + T+P FP+ YP C W + ++L F FDL
Sbjct: 211 DNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLAS--- 267
Query: 259 YQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT----SDGSVLRVQFTSDGSVHRS 314
E D VTV++ L CGT PP S +VL + ++
Sbjct: 268 -CDERGSDLVTVYNTLSPMEPHALVQLCGT-YPPSYNLTFHSSQNVLLITLITNTERRHP 325
Query: 315 GFAAVYY 321
GF A ++
Sbjct: 326 GFEATFF 332
Score = 31.5 bits (68), Expect = 9.5
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 4/123 (3%)
Query: 475 THSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELERE 534
T +C L A ++ + D+ Y + A C W + + + LTF +F+L
Sbjct: 209 TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASC 268
Query: 535 ANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFS 590
D V V+ CG P S+ LL+ T+ GF
Sbjct: 269 DERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFE 328
Query: 591 ASY 593
A++
Sbjct: 329 ATF 331
>AF133086-1|AAF00109.1| 855|Homo sapiens membrane-type serine
protease 1 protein.
Length = 855
Score = 76.2 bits (179), Expect = 3e-13
Identities = 64/228 (28%), Positives = 93/228 (40%), Gaps = 27/228 (11%)
Query: 380 SPNYP-AAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKT 437
+P +P + YPA C W + L F F+L E D VT+Y+ S +
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 438 LGIFCGSKLPHLVM---ASQNQMYMVFKSDGSVQRKGFLAT-----HSTACGGYLSATEE 489
L CG+ P + +SQN + + ++ + GF AT ++CGG L +
Sbjct: 290 LVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQG 349
Query: 490 VKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER----EANCRYDYVQVF 545
++ Y Y DC WNIE P N VK+ F F L C DYV++
Sbjct: 350 T----FNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI- 404
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + + S S + VRF +D S GF A Y
Sbjct: 405 --------NGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 34/189 (17%)
Query: 39 HRGFRA-FYE----AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF 93
H GF A F++ + CGG + + G SP YP Y PN C W + VP + V +RF
Sbjct: 324 HPGFEATFFQLPRMSSCGGRLR-KAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRF 382
Query: 94 HSFEVEN----HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
F + TC D V++ +G+ +CG + + S SNK+ V F SD
Sbjct: 383 KFFYLLEPGVPAGTCPKDYVEI-NGEK--------YCGERSQFVVTSNSNKITVRFHSDQ 433
Query: 150 TVQKAGFSATFMK---------EF----DECASIDHGCS--HSCVNTLGGYECACDIGYE 194
+ GF A ++ +F C + C C + C+CD G++
Sbjct: 434 SYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQ 493
Query: 195 LHSDGKKCE 203
K C+
Sbjct: 494 FTCKNKFCK 502
Score = 59.3 bits (137), Expect = 4e-08
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 16/154 (10%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
++CGG L GT SP +P YPP +C W I P + + F F L + C
Sbjct: 338 SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTC 397
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY--Y 321
D V ++ + +CG VTS+ + + V+F SD S +GF A Y Y
Sbjct: 398 PKDYVEINGE----------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSY 447
Query: 322 IDVDECAE----NNGGCQHECHNTLGGYECACHS 351
D C G C + G +C HS
Sbjct: 448 DSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHS 481
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFEL----EPHQECAYDHVTIYDGA 431
GT SP YP YP DC W +K+ F F L P C D+V I +G
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI-NGE 407
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+CG + +V ++ N++ + F SD S GFLA +
Sbjct: 408 K--------YCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 64 SPNYPDD-YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS-MDSPL 121
+P +PD Y + C W L D ++L F SF++ + D D V V + S M+
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 122 IGMFCGHKIPPD----IRSTSNKLLVIFESDSTVQKAGFSATFMK 162
+ CG PP S+ N LL+ +++ + GF ATF +
Sbjct: 290 LVQLCG-TYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQ 333
Score = 34.7 bits (76), Expect = 1.0
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 203 ENACGGALYGPNGTI---TSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHM 258
+N+C L+ + T+P FP+ YP C W + ++L F FDL
Sbjct: 211 DNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLAS--- 267
Query: 259 YQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT----SDGSVLRVQFTSDGSVHRS 314
E D VTV++ L CGT PP S +VL + ++
Sbjct: 268 -CDERGSDLVTVYNTLSPMEPHALVQLCGT-YPPSYNLTFHSSQNVLLITLITNTERRHP 325
Query: 315 GFAAVYY 321
GF A ++
Sbjct: 326 GFEATFF 332
Score = 31.5 bits (68), Expect = 9.5
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 4/123 (3%)
Query: 475 THSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELERE 534
T +C L A ++ + D+ Y + A C W + + + LTF +F+L
Sbjct: 209 TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASC 268
Query: 535 ANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFS 590
D V V+ CG P S+ LL+ T+ GF
Sbjct: 269 DERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFE 328
Query: 591 ASY 593
A++
Sbjct: 329 ATF 331
>AF118224-1|AAD42765.2| 855|Homo sapiens matriptase protein.
Length = 855
Score = 76.2 bits (179), Expect = 3e-13
Identities = 64/228 (28%), Positives = 93/228 (40%), Gaps = 27/228 (11%)
Query: 380 SPNYP-AAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKT 437
+P +P + YPA C W + L F F+L E D VT+Y+ S +
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 438 LGIFCGSKLPHLVM---ASQNQMYMVFKSDGSVQRKGFLAT-----HSTACGGYLSATEE 489
L CG+ P + +SQN + + ++ + GF AT ++CGG L +
Sbjct: 290 LVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQG 349
Query: 490 VKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER----EANCRYDYVQVF 545
++ Y Y DC WNIE P N VK+ F F L C DYV++
Sbjct: 350 T----FNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI- 404
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + + S S + VRF +D S GF A Y
Sbjct: 405 --------NGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 34/189 (17%)
Query: 39 HRGFRA-FYE----AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF 93
H GF A F++ + CGG + + G SP YP Y PN C W + VP + V +RF
Sbjct: 324 HPGFEATFFQLPRMSSCGGRLR-KAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRF 382
Query: 94 HSFEVEN----HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
F + TC D V++ +G+ +CG + + S SNK+ V F SD
Sbjct: 383 KFFYLLEPGVPAGTCPKDYVEI-NGEK--------YCGERSQFVVTSNSNKITVRFHSDQ 433
Query: 150 TVQKAGFSATFMK---------EF----DECASIDHGCS--HSCVNTLGGYECACDIGYE 194
+ GF A ++ +F C + C C + C+CD G++
Sbjct: 434 SYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQ 493
Query: 195 LHSDGKKCE 203
K C+
Sbjct: 494 FTCKNKFCK 502
Score = 59.3 bits (137), Expect = 4e-08
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 16/154 (10%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
++CGG L GT SP +P YPP +C W I P + + F F L + C
Sbjct: 338 SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTC 397
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY--Y 321
D V ++ + +CG VTS+ + + V+F SD S +GF A Y Y
Sbjct: 398 PKDYVEINGE----------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSY 447
Query: 322 IDVDECAE----NNGGCQHECHNTLGGYECACHS 351
D C G C + G +C HS
Sbjct: 448 DSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHS 481
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFEL----EPHQECAYDHVTIYDGA 431
GT SP YP YP DC W +K+ F F L P C D+V I +G
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI-NGE 407
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+CG + +V ++ N++ + F SD S GFLA +
Sbjct: 408 K--------YCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 64 SPNYPDD-YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS-MDSPL 121
+P +PD Y + C W L D ++L F SF++ + D D V V + S M+
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 122 IGMFCGHKIPPD----IRSTSNKLLVIFESDSTVQKAGFSATFMK 162
+ CG PP S+ N LL+ +++ + GF ATF +
Sbjct: 290 LVQLCG-TYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQ 333
Score = 34.7 bits (76), Expect = 1.0
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 203 ENACGGALYGPNGTI---TSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHM 258
+N+C L+ + T+P FP+ YP C W + ++L F FDL
Sbjct: 211 DNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLAS--- 267
Query: 259 YQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT----SDGSVLRVQFTSDGSVHRS 314
E D VTV++ L CGT PP S +VL + ++
Sbjct: 268 -CDERGSDLVTVYNTLSPMEPHALVQLCGT-YPPSYNLTFHSSQNVLLITLITNTERRHP 325
Query: 315 GFAAVYY 321
GF A ++
Sbjct: 326 GFEATFF 332
Score = 31.5 bits (68), Expect = 9.5
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 4/123 (3%)
Query: 475 THSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELERE 534
T +C L A ++ + D+ Y + A C W + + + LTF +F+L
Sbjct: 209 TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASC 268
Query: 535 ANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFS 590
D V V+ CG P S+ LL+ T+ GF
Sbjct: 269 DERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFE 328
Query: 591 ASY 593
A++
Sbjct: 329 ATF 331
>AB030036-1|BAB20376.1| 855|Homo sapiens prostamin protein.
Length = 855
Score = 76.2 bits (179), Expect = 3e-13
Identities = 64/228 (28%), Positives = 93/228 (40%), Gaps = 27/228 (11%)
Query: 380 SPNYP-AAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA-DVKT 437
+P +P + YPA C W + L F F+L E D VT+Y+ S +
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 438 LGIFCGSKLPHLVM---ASQNQMYMVFKSDGSVQRKGFLAT-----HSTACGGYLSATEE 489
L CG+ P + +SQN + + ++ + GF AT ++CGG L +
Sbjct: 290 LVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMSSCGGRLRKAQG 349
Query: 490 VKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELER----EANCRYDYVQVF 545
++ Y Y DC WNIE P N VK+ F F L C DYV++
Sbjct: 350 T----FNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI- 404
Query: 546 XXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
+CG + + S S + VRF +D S GF A Y
Sbjct: 405 --------NGEKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 60.5 bits (140), Expect = 2e-08
Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 34/189 (17%)
Query: 39 HRGFRA-FYE----AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRF 93
H GF A F++ + CGG + + G SP YP Y PN C W + VP + V +RF
Sbjct: 324 HPGFEATFFQLPRMSSCGGRLR-KAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRF 382
Query: 94 HSFEVEN----HDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDS 149
F + TC D V++ +G+ +CG + + S SNK+ V F SD
Sbjct: 383 KFFYLLEPGVPAGTCPKDYVEI-NGEK--------YCGERSQFVVTSNSNKITVRFHSDQ 433
Query: 150 TVQKAGFSATFMK---------EF----DECASIDHGCS--HSCVNTLGGYECACDIGYE 194
+ GF A ++ +F C + C C + C+CD G++
Sbjct: 434 SYTDTGFLAEYLSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQ 493
Query: 195 LHSDGKKCE 203
K C+
Sbjct: 494 FTCKNKFCK 502
Score = 59.3 bits (137), Expect = 4e-08
Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 16/154 (10%)
Query: 204 NACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQEC 263
++CGG L GT SP +P YPP +C W I P + + F F L + C
Sbjct: 338 SSCGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTC 397
Query: 264 EYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY--Y 321
D V ++ + +CG VTS+ + + V+F SD S +GF A Y Y
Sbjct: 398 PKDYVEINGE----------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSY 447
Query: 322 IDVDECAE----NNGGCQHECHNTLGGYECACHS 351
D C G C + G +C HS
Sbjct: 448 DSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHS 481
Score = 50.0 bits (114), Expect = 3e-05
Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 13/105 (12%)
Query: 376 GTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFEL----EPHQECAYDHVTIYDGA 431
GT SP YP YP DC W +K+ F F L P C D+V I +G
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEI-NGE 407
Query: 432 SADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+CG + +V ++ N++ + F SD S GFLA +
Sbjct: 408 K--------YCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 41.5 bits (93), Expect = 0.009
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 64 SPNYPDD-YQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDS-MDSPL 121
+P +PD Y + C W L D ++L F SF++ + D D V V + S M+
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHA 289
Query: 122 IGMFCGHKIPPD----IRSTSNKLLVIFESDSTVQKAGFSATFMK 162
+ CG PP S+ N LL+ +++ + GF ATF +
Sbjct: 290 LVQLCG-TYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQ 333
Score = 34.7 bits (76), Expect = 1.0
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 203 ENACGGALYGPNGTI---TSPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHM 258
+N+C L+ + T+P FP+ YP C W + ++L F FDL
Sbjct: 211 DNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLAS--- 267
Query: 259 YQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVT----SDGSVLRVQFTSDGSVHRS 314
E D VTV++ L CGT PP S +VL + ++
Sbjct: 268 -CDERGSDLVTVYNTLSPMEPHALVQLCGT-YPPSYNLTFHSSQNVLLITLITNTERRHP 325
Query: 315 GFAAVYY 321
GF A ++
Sbjct: 326 GFEATFF 332
Score = 31.5 bits (68), Expect = 9.5
Identities = 27/123 (21%), Positives = 44/123 (35%), Gaps = 4/123 (3%)
Query: 475 THSTACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELERE 534
T +C L A ++ + D+ Y + A C W + + + LTF +F+L
Sbjct: 209 TQDNSCSFGLHARGVELMRFTTPGFPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASC 268
Query: 535 ANCRYDYVQVFXXXX-XXXXXXXTFCGIKMPP---EIVSTSEALLVRFRTDDSLVFKGFS 590
D V V+ CG P S+ LL+ T+ GF
Sbjct: 269 DERGSDLVTVYNTLSPMEPHALVQLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFE 328
Query: 591 ASY 593
A++
Sbjct: 329 ATF 331
>BX640971-1|CAE45986.1| 1221|Homo sapiens hypothetical protein
protein.
Length = 1221
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>BX640873-1|CAE45930.1| 1198|Homo sapiens hypothetical protein
protein.
Length = 1198
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 46 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 105
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 106 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 151
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 54 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 113
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 114 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 153
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 43 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 97
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 98 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 151
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 64 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 123
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 124 SFN----SSANEMHVSFSSDFSIQKKGFNASY 151
>BC075798-1|AAH75798.1| 1222|Homo sapiens GPR126 protein protein.
Length = 1222
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>AF216967-1|AAO13250.1| 1222|Homo sapiens putative vascular
inducible G protein-coupled receptor protein.
Length = 1222
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>AB183549-1|BAD27574.1| 1222|Homo sapiens developmentally regulated
G-protein-coupled receptor beta 2 protein.
Length = 1222
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>AB183548-1|BAD27573.1| 1250|Homo sapiens developmentally regulated
G-protein-coupled receptor beta 1 protein.
Length = 1250
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>AB183547-1|BAD27572.1| 1193|Homo sapiens developmentally regulated
G-protein-coupled receptor alpha 2 protein.
Length = 1193
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>AB183546-1|BAD27571.1| 1221|Homo sapiens developmentally regulated
G-protein-coupled receptor alpha 1 protein.
Length = 1221
Score = 75.4 bits (177), Expect = 6e-13
Identities = 39/111 (35%), Positives = 62/111 (55%), Gaps = 6/111 (5%)
Query: 367 CKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVT 426
C+ ++ P GT SP YP YP + C+W G+ I++ FN F++E C YD ++
Sbjct: 41 CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS 100
Query: 427 IYDGASADVKTLGIFCGSKLPHLVM-ASQNQMYMVFKSDGSVQRKGFLATH 476
+ +G S FCG+ L +S N+M++ F SD S+Q+KGF A++
Sbjct: 101 LDNGESQTK-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 74.1 bits (174), Expect = 1e-12
Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 6/105 (5%)
Query: 59 NGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMD 118
+G SP YP+DY ++ C+W L P Y + + F+ F++E C YD + + +G+S
Sbjct: 49 SGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQT 108
Query: 119 SPLIGMFCGHKIPP-DIRSTSNKLLVIFESDSTVQKAGFSATFMK 162
FCG S++N++ V F SD ++QK GF+A++++
Sbjct: 109 K-----FCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASYIR 148
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 12/120 (10%)
Query: 202 CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQ 261
C N C L P+GT TSP +P YP + C+W + AP + I + F FD+E
Sbjct: 38 CAN-CRVVLSNPSGTFTSPCYPNDYPNSQACMWTLRAPTGYIIQITFNDFDIE----EAP 92
Query: 262 ECEYDSVTVHSKLGADVLRRHGAFCG-TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY 320
C YDS L D FCG TA S + + V F+SD S+ + GF A Y
Sbjct: 93 NCIYDS------LSLDNGESQTKFCGATAKGLSFNSSANEMHVSFSSDFSIQKKGFNASY 146
Score = 50.8 bits (116), Expect = 1e-05
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 502 NAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGI 561
N Y + C W + AP + +++TF F++E NC YD + + T G+
Sbjct: 59 NDYPNSQACMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLSLDNGESQTKFCGATAKGL 118
Query: 562 KMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
S++ + V F +D S+ KGF+ASY
Sbjct: 119 SFN----SSANEMHVSFSSDFSIQKKGFNASY 146
>Y19124-1|CAB65555.1| 1019|Homo sapiens enteropeptidase protein.
Length = 1019
Score = 72.1 bits (169), Expect = 5e-12
Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 5/112 (4%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG E+ + N S N+P+ Y C+W L+ + + L F F++EN + D
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENIN----DV 579
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V++RDG+ DS L+ ++ G D+ ST+N++ V+ ++ + + GF A F
Sbjct: 580 VEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 55.6 bits (128), Expect = 5e-07
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P+ T S N+P +YP CVW + G I+L F F+LE D V I DG A
Sbjct: 533 PNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLEN----INDVVEIRDGEEA 588
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
D L ++ G V ++ N+M ++ ++ + R GF A +T G +L E K
Sbjct: 589 DSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTT--GYHLGIPEPCKAD 646
Query: 494 YSHARYGD 501
+ + G+
Sbjct: 647 HFQCKNGE 654
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 206 CGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
CGG L+ PN T +S +FP YP L C+W + A I L+F FDLE
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE 574
Score = 37.5 bits (83), Expect = 0.14
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
T CGG E +S + N+Y + A C W + A + ++L F F+LE N
Sbjct: 522 TDCGGPFELWEP-NTTFSSTNF-PNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE-NIN- 577
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D V++ + G ++ ST+ + V T+D L GF A++
Sbjct: 578 --DVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 35.1 bits (77), Expect = 0.77
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 49 VCGGD-IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
VC G + S+G ++ +YP + + +C W + V Q + L F F +T D
Sbjct: 224 VCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDF-----NTYYTD 278
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIF--ESDSTVQKAGFSATF 160
+ + +G S ++ P IR SN++ F ESD + GF+AT+
Sbjct: 279 ILDIYEGVG-SSKILRASIWETNPGTIRIFSNQVTATFLIESDES-DYVGFNATY 331
>U09860-1|AAC50138.1| 1019|Homo sapiens enterokinase protein.
Length = 1019
Score = 72.1 bits (169), Expect = 5e-12
Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 5/112 (4%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG E+ + N S N+P+ Y C+W L+ + + L F F++EN + D
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENIN----DV 579
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V++RDG+ DS L+ ++ G D+ ST+N++ V+ ++ + + GF A F
Sbjct: 580 VEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 55.6 bits (128), Expect = 5e-07
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P+ T S N+P +YP CVW + G I+L F F+LE D V I DG A
Sbjct: 533 PNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLEN----INDVVEIRDGEEA 588
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
D L ++ G V ++ N+M ++ ++ + R GF A +T G +L E K
Sbjct: 589 DSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTT--GYHLGIPEPCKAD 646
Query: 494 YSHARYGD 501
+ + G+
Sbjct: 647 HFQCKNGE 654
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 206 CGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
CGG L+ PN T +S +FP YP L C+W + A I L+F FDLE
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE 574
Score = 37.5 bits (83), Expect = 0.14
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
T CGG E +S + N+Y + A C W + A + ++L F F+LE N
Sbjct: 522 TDCGGPFELWEP-NTTFSSTNF-PNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE-NIN- 577
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D V++ + G ++ ST+ + V T+D L GF A++
Sbjct: 578 --DVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 35.1 bits (77), Expect = 0.77
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 49 VCGGD-IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
VC G + S+G ++ +YP + + +C W + V Q + L F F +T D
Sbjct: 224 VCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDF-----NTYYTD 278
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIF--ESDSTVQKAGFSATF 160
+ + +G S ++ P IR SN++ F ESD + GF+AT+
Sbjct: 279 ILDIYEGVG-SSKILRASIWETNPGTIRIFSNQVTATFLIESDES-DYVGFNATY 331
>BC111749-1|AAI11750.1| 1019|Homo sapiens protease, serine, 7
(enterokinase) protein.
Length = 1019
Score = 72.1 bits (169), Expect = 5e-12
Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 5/112 (4%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG E+ + N S N+P+ Y C+W L+ + + L F F++EN + D
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENIN----DV 579
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V++RDG+ DS L+ ++ G D+ ST+N++ V+ ++ + + GF A F
Sbjct: 580 VEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 55.6 bits (128), Expect = 5e-07
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P+ T S N+P +YP CVW + G I+L F F+LE D V I DG A
Sbjct: 533 PNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLEN----INDVVEIRDGEEA 588
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
D L ++ G V ++ N+M ++ ++ + R GF A +T G +L E K
Sbjct: 589 DSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTT--GYHLGIPEPCKAD 646
Query: 494 YSHARYGD 501
+ + G+
Sbjct: 647 HFQCKNGE 654
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 206 CGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
CGG L+ PN T +S +FP YP L C+W + A I L+F FDLE
Sbjct: 524 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE 574
Score = 37.5 bits (83), Expect = 0.14
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
T CGG E +S + N+Y + A C W + A + ++L F F+LE N
Sbjct: 522 TDCGGPFELWEP-NTTFSSTNF-PNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE-NIN- 577
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D V++ + G ++ ST+ + V T+D L GF A++
Sbjct: 578 --DVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 631
Score = 35.1 bits (77), Expect = 0.77
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 49 VCGGD-IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
VC G + S+G ++ +YP + + +C W + V Q + L F F +T D
Sbjct: 224 VCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDF-----NTYYTD 278
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIF--ESDSTVQKAGFSATF 160
+ + +G S ++ P IR SN++ F ESD + GF+AT+
Sbjct: 279 ILDIYEGVG-SSKILRASIWETNPGTIRIFSNQVTATFLIESDES-DYVGFNATY 331
>AL163217-2|CAB90389.1| 904|Homo sapiens human enterokinase; EC
3.4.21.9. protein.
Length = 904
Score = 72.1 bits (169), Expect = 5e-12
Identities = 35/112 (31%), Positives = 61/112 (54%), Gaps = 5/112 (4%)
Query: 50 CGGDIEV-DSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDK 108
CGG E+ + N S N+P+ Y C+W L+ + + L F F++EN + D
Sbjct: 409 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENIN----DV 464
Query: 109 VKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
V++RDG+ DS L+ ++ G D+ ST+N++ V+ ++ + + GF A F
Sbjct: 465 VEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 516
Score = 55.6 bits (128), Expect = 5e-07
Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 6/128 (4%)
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
P+ T S N+P +YP CVW + G I+L F F+LE D V I DG A
Sbjct: 418 PNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLEN----INDVVEIRDGEEA 473
Query: 434 DVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACGGYLSATEEVKHL 493
D L ++ G V ++ N+M ++ ++ + R GF A +T G +L E K
Sbjct: 474 DSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTT--GYHLGIPEPCKAD 531
Query: 494 YSHARYGD 501
+ + G+
Sbjct: 532 HFQCKNGE 539
Score = 46.4 bits (105), Expect = 3e-04
Identities = 23/51 (45%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 206 CGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
CGG L+ PN T +S +FP YP L C+W + A I L+F FDLE
Sbjct: 409 CGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE 459
Score = 37.5 bits (83), Expect = 0.14
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 6/116 (5%)
Query: 478 TACGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANC 537
T CGG E +S + N+Y + A C W + A + ++L F F+LE N
Sbjct: 407 TDCGGPFELWEP-NTTFSSTNF-PNSYPNLAFCVWILNAQKGKNIQLHFQEFDLE-NIN- 462
Query: 538 RYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
D V++ + G ++ ST+ + V T+D L GF A++
Sbjct: 463 --DVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANF 516
Score = 35.1 bits (77), Expect = 0.77
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 49 VCGGD-IEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
VC G + S+G ++ +YP + + +C W + V Q + L F F +T D
Sbjct: 109 VCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDF-----NTYYTD 163
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIF--ESDSTVQKAGFSATF 160
+ + +G S ++ P IR SN++ F ESD + GF+AT+
Sbjct: 164 ILDIYEGVG-SSKILRASIWETNPGTIRIFSNQVTATFLIESDES-DYVGFNATY 216
>CR456574-1|CAG30460.1| 948|Homo sapiens SEZ6L protein.
Length = 948
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>BC126115-1|AAI26116.1| 1024|Homo sapiens seizure related 6 homolog
(mouse)-like protein.
Length = 1024
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>BC111690-1|AAI11691.1| 807|Homo sapiens SCUBE2 protein protein.
Length = 807
Score = 70.5 bits (165), Expect = 2e-11
Identities = 26/41 (63%), Positives = 29/41 (70%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC ENNGGCQH C N +G YEC C GF L N+H C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 66.9 bits (156), Expect = 2e-10
Identities = 25/40 (62%), Positives = 29/40 (72%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D +EC+ NNGGCQ C NT+G YEC CH G+ LH NK DC
Sbjct: 403 DTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 442
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 37/229 (16%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYEL------------HSDGKKCENACGGALYGP 213
C + DHGCSH C G C C G+EL H +G C+++C GP
Sbjct: 177 CMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGG-CQHSCDDTADGP 235
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+ P + +++ ++CL +T + T ++G+ ++ ++ V++
Sbjct: 236 ECSC-HPQY-KMHTDGRSCLER--EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGG 333
G D + + G PV G L++ DG + D+DEC NGG
Sbjct: 292 -GCDRTCKDTS-TGVHCSCPV---GFTLQL----DGKTCK---------DIDECQTRNGG 333
Query: 334 CQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
C H C N +G ++C C GF L ++ C++ C D T H I P
Sbjct: 334 CDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHP 382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 9/56 (16%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
D+DEC E NGGC H+C N G Y C C GF L + H+C GGC+H
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH 141
Score = 53.2 bits (122), Expect = 3e-06
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
+ T + +EC+ + GC CVNT+G YEC C GY+LH + K C +C
Sbjct: 396 YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVASC 446
Score = 50.4 bits (115), Expect = 2e-05
Identities = 17/43 (39%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + + GC H C N +G ++C C G++L +D K C++
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD 364
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC H+CVN +G YEC C G+ L + C
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 115 DSMDSPLIGMFCGHKIPPDIRSTSNK---LLVIFESDSTVQKAGFSATFMKEFDE-CASI 170
D+ D P +K+ D RS + +L + ES++T G + E CA
Sbjct: 230 DTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVN 289
Query: 171 DHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ GC +C +T G C+C +G+ L DGK C++
Sbjct: 290 NGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKD 323
Score = 44.4 bits (100), Expect = 0.001
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECAS-IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + ++ GC H C+N G Y C C G+ L DG C
Sbjct: 85 EDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 44.0 bits (99), Expect = 0.002
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S+D C HSC+N G + CAC+ GY L+
Sbjct: 363 QDVDEC-SLDRTCDHSCINHPGTFACACNRGYTLY 396
Score = 42.3 bits (95), Expect = 0.005
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCKHDVTLPH 375
DVDEC+ + C H C N G + CAC+ G+TL+ H +C GGC+
Sbjct: 364 DVDECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTV 422
Query: 376 GTIFSPNYPA--AYPARKDCV 394
G+ +P + +KDCV
Sbjct: 423 GSYECQCHPGYKLHWNKKDCV 443
Score = 37.5 bits (83), Expect = 0.14
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCE--NACGGAL 210
G +A ++ DECA C C NT Y+C+C GY+ +G++CE + CG L
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNEL 94
Query: 211 YG 212
G
Sbjct: 95 NG 96
Score = 36.7 bits (81), Expect = 0.25
Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
Query: 315 GFAAVYYIDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNK-HDCKE------G 365
G AA DVDECA+ C + C NT Y+C+C G+ + D E G
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNG 96
Query: 366 GCKHD 370
GC HD
Sbjct: 97 GCVHD 101
>AY358405-1|AAQ88771.1| 1023|Homo sapiens SEZ6L protein.
Length = 1023
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>AL078460-1|CAI20266.1| 949|Homo sapiens seizure related 6 homolog
(mouse)-like protein.
Length = 949
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>AL050253-1|CAB43355.1| 792|Homo sapiens hypothetical protein
protein.
Length = 792
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 221 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 274
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 275 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 331
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 332 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 391
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 392 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 451
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 452 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 493
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 211 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 270
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 271 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 325
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 326 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 385
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 386 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 445
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 446 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 494
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 495 AGLIFGKGQGFIMNYIEVSRNDSCSD 520
>AL035545-1|CAB37431.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 221 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 274
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 275 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 331
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 332 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 391
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 392 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 451
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 452 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 493
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 211 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 270
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 271 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 325
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 326 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 385
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 386 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 445
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 446 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 494
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 495 AGLIFGKGQGFIMNYIEVSRNDSCSD 520
>AL023513-2|CAI19980.1| 949|Homo sapiens seizure related 6 homolog
(mouse)-like protein.
Length = 949
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>AL022337-1|CAI17997.1| 949|Homo sapiens seizure related 6 homolog
(mouse)-like protein.
Length = 949
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>AK131552-1|BAD18686.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ16792 fis, clone TBAES2007379, moderately
similar to Homo sapiens signal peptide, CUB domain,
EGF-like 2 (SCUBE2). ).
Length = 682
Score = 70.5 bits (165), Expect = 2e-11
Identities = 26/41 (63%), Positives = 29/41 (70%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC ENNGGCQH C N +G YEC C GF L N+H C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 66.9 bits (156), Expect = 2e-10
Identities = 25/40 (62%), Positives = 29/40 (72%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D +EC+ NNGGCQ C NT+G YEC CH G+ LH NK DC
Sbjct: 403 DTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 442
Score = 64.5 bits (150), Expect = 1e-09
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 37/229 (16%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYEL------------HSDGKKCENACGGALYGP 213
C + DHGCSH C G C C G+EL H +G C+++C GP
Sbjct: 177 CMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGG-CQHSCDDTADGP 235
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+ P + +++ ++CL +T + T ++G+ +++ ++ V++
Sbjct: 236 ECSC-HPQY-KMHTDGRSCLER--EDTVLEVTESNTTSVVDGDKRVKRQLLMETCAVNNG 291
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGG 333
G D + + G PV G L++ DG + D+DEC NGG
Sbjct: 292 -GCDRTCKDTS-TGVHCSCPV---GFTLQL----DGKTCK---------DIDECQTRNGG 333
Query: 334 CQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
C H C N +G ++C C GF L ++ C++ C D T H I P
Sbjct: 334 CDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHP 382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 9/56 (16%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
D+DEC E NGGC H+C N G Y C C GF L + H+C GGC+H
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH 141
Score = 53.2 bits (122), Expect = 3e-06
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
+ T + +EC+ + GC CVNT+G YEC C GY+LH + K C +C
Sbjct: 396 YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVASC 446
Score = 50.4 bits (115), Expect = 2e-05
Identities = 17/43 (39%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + + GC H C N +G ++C C G++L +D K C++
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD 364
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC H+CVN +G YEC C G+ L + C
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 45.2 bits (102), Expect = 7e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 115 DSMDSPLIGMFCGHKIPPDIRSTSNK---LLVIFESDSTVQKAGFSATFMKEFDE-CASI 170
D+ D P +K+ D RS + +L + ES++T G + E CA
Sbjct: 230 DTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRQLLMETCAVN 289
Query: 171 DHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ GC +C +T G C+C +G+ L DGK C++
Sbjct: 290 NGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKD 323
Score = 44.4 bits (100), Expect = 0.001
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECAS-IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + ++ GC H C+N G Y C C G+ L DG C
Sbjct: 85 EDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 44.0 bits (99), Expect = 0.002
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S+D C HSC+N G + CAC+ GY L+
Sbjct: 363 QDVDEC-SLDRTCDHSCINHPGTFACACNRGYTLY 396
Score = 42.3 bits (95), Expect = 0.005
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCKHDVTLPH 375
DVDEC+ + C H C N G + CAC+ G+TL+ H +C GGC+
Sbjct: 364 DVDECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTV 422
Query: 376 GTIFSPNYPA--AYPARKDCV 394
G+ +P + +KDCV
Sbjct: 423 GSYECQCHPGYKLHWNKKDCV 443
Score = 37.5 bits (83), Expect = 0.14
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCE--NACGGAL 210
G +A ++ DECA C C NT Y+C+C GY+ +G++CE + CG L
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNEL 94
Query: 211 YG 212
G
Sbjct: 95 NG 96
Score = 36.7 bits (81), Expect = 0.25
Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
Query: 315 GFAAVYYIDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNK-HDCKE------G 365
G AA DVDECA+ C + C NT Y+C+C G+ + D E G
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNG 96
Query: 366 GCKHD 370
GC HD
Sbjct: 97 GCVHD 101
>AK123039-1|BAC85521.1| 971|Homo sapiens protein ( Homo sapiens
cDNA FLJ41044 fis, clone NT2RP7000466, highly similar
to Mus musculus CUB domain and EGF-like repeat
containing 1 (Cegf1). ).
Length = 971
Score = 70.5 bits (165), Expect = 2e-11
Identities = 26/41 (63%), Positives = 29/41 (70%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC ENNGGCQH C N +G YEC C GF L N+H C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 68.1 bits (159), Expect = 9e-11
Identities = 26/42 (61%), Positives = 30/42 (71%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D +EC+ NNGGCQ C NT+G YEC CH G+ LH NK DC E
Sbjct: 403 DTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 37/229 (16%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYEL------------HSDGKKCENACGGALYGP 213
C + DHGCSH C G C C G+EL H +G C+++C GP
Sbjct: 177 CMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGG-CQHSCDDTADGP 235
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+ P + +++ ++CL +T + T ++G+ ++ ++ V++
Sbjct: 236 ECSC-HPQY-KMHTDGRSCLER--EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGG 333
G D + + G PV G L++ DG + D+DEC NGG
Sbjct: 292 -GCDRTCKDTS-TGVHCSCPV---GFTLQL----DGKTCK---------DIDECQTRNGG 333
Query: 334 CQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
C H C N +G ++C C GF L ++ C++ C D T H I P
Sbjct: 334 CDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHP 382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 9/56 (16%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
D+DEC E NGGC H+C N G Y C C GF L + H+C GGC+H
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH 141
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 2/134 (1%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N CK C ++ G I SPNYP YPA +C W + P RI ++ L
Sbjct: 772 NITQCKNRRCGGELGDFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLPIE 831
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+C D++ + +S++ T C + + P + ++++ FKS+ +GF +
Sbjct: 832 DDCG-DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQGPY 890
Query: 477 STACGGYLSATEEV 490
T Y E++
Sbjct: 891 VTYDEDYQELIEDI 904
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ D G++ESPNYP +Y N C W ++ P ++ + + D C D +
Sbjct: 781 CGGELG-DFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLPIEDDCG-DYL 838
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S +S C ++ P S S KL + F+S+ GF ++ +DE
Sbjct: 839 VMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQGPYV-TYDE 895
Score = 51.2 bits (117), Expect = 1e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACG 207
+ T + +EC+ + GC CVNT+G YEC C GY+LH + K C G
Sbjct: 396 YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKG 447
Score = 50.4 bits (115), Expect = 2e-05
Identities = 17/43 (39%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + + GC H C N +G ++C C G++L +D K C++
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD 364
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC H+CVN +G YEC C G+ L + C
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 115 DSMDSPLIGMFCGHKIPPDIRSTSNK---LLVIFESDSTVQKAGFSATFMKEFDE-CASI 170
D+ D P +K+ D RS + +L + ES++T G + E CA
Sbjct: 230 DTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVN 289
Query: 171 DHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ GC +C +T G C+C +G+ L DGK C++
Sbjct: 290 NGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKD 323
Score = 44.4 bits (100), Expect = 0.001
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECAS-IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + ++ GC H C+N G Y C C G+ L DG C
Sbjct: 85 EDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 44.0 bits (99), Expect = 0.002
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S+D C HSC+N G + CAC+ GY L+
Sbjct: 363 QDVDEC-SLDRTCDHSCINHPGTFACACNRGYTLY 396
Score = 44.0 bits (99), Expect = 0.002
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
+C+N CGG L G I SP++P YP C W I PP+ RI + L
Sbjct: 775 QCKNRRCGGELGDFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLP----I 830
Query: 260 QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ +C D + + ++ + + P TS L +QF S+ GF
Sbjct: 831 EDDCG-DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQGP 889
Query: 320 YYIDVDE 326
Y+ DE
Sbjct: 890 -YVTYDE 895
Score = 42.3 bits (95), Expect = 0.005
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCKHDVTLPH 375
DVDEC+ + C H C N G + CAC+ G+TL+ H +C GGC+
Sbjct: 364 DVDECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTV 422
Query: 376 GTIFSPNYPA--AYPARKDCV 394
G+ +P + +KDCV
Sbjct: 423 GSYECQCHPGYKLHWNKKDCV 443
Score = 37.5 bits (83), Expect = 0.14
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCE--NACGGAL 210
G +A ++ DECA C C NT Y+C+C GY+ +G++CE + CG L
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNEL 94
Query: 211 YG 212
G
Sbjct: 95 NG 96
Score = 36.7 bits (81), Expect = 0.25
Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
Query: 315 GFAAVYYIDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNK-HDCKE------G 365
G AA DVDECA+ C + C NT Y+C+C G+ + D E G
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNG 96
Query: 366 GCKHD 370
GC HD
Sbjct: 97 GCVHD 101
Score = 31.5 bits (68), Expect = 9.5
Identities = 25/115 (21%), Positives = 42/115 (36%), Gaps = 6/115 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L + Y N Y + +C W I P + + L E +C
Sbjct: 781 CGGELG---DFTGYIESPNYPGN-YPANTECTWTINPPPKRRILIVVPEIFLPIEDDCG- 835
Query: 540 DYVQVFXXXXXXXXXXXTFC-GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
DY+ + C + P S S+ L ++F++++ +GF Y
Sbjct: 836 DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQGPY 890
>AJ400877-1|CAB92285.1| 999|Homo sapiens CEGP1 protein protein.
Length = 999
Score = 70.5 bits (165), Expect = 2e-11
Identities = 26/41 (63%), Positives = 29/41 (70%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC ENNGGCQH C N +G YEC C GF L N+H C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 68.1 bits (159), Expect = 9e-11
Identities = 26/42 (61%), Positives = 30/42 (71%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D +EC+ NNGGCQ C NT+G YEC CH G+ LH NK DC E
Sbjct: 403 DTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVE 444
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 37/229 (16%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYEL------------HSDGKKCENACGGALYGP 213
C + DHGCSH C G C C G+EL H +G C+++C GP
Sbjct: 177 CMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGG-CQHSCDDTADGP 235
Query: 214 NGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSK 273
+ P + +++ ++CL +T + T ++G+ ++ ++ V++
Sbjct: 236 ECSC-HPQY-KMHTDGRSCLER--EDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 274 LGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGG 333
G D + + G PV G L++ DG + D+DEC NGG
Sbjct: 292 -GCDRTCKDTS-TGVHCSCPV---GFTLQL----DGKTCK---------DIDECQTRNGG 333
Query: 334 CQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
C H C N +G ++C C GF L ++ C++ C D T H I P
Sbjct: 334 CDHFCKNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCINHP 382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 25/56 (44%), Positives = 30/56 (53%), Gaps = 9/56 (16%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
D+DEC E NGGC H+C N G Y C C GF L + H+C GGC+H
Sbjct: 86 DIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQH 141
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 2/134 (1%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N CK C ++ G I SPNYP YPA +C W + P RI ++ L
Sbjct: 800 NITQCKNRRCGGELGDFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLPIE 859
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
+C D++ + +S++ T C + + P + ++++ FKS+ +GF +
Sbjct: 860 DDCG-DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQVPY 918
Query: 477 STACGGYLSATEEV 490
T Y E++
Sbjct: 919 VTYDEDYQELIEDI 932
Score = 53.6 bits (123), Expect = 2e-06
Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ D G++ESPNYP +Y N C W ++ P ++ + + D C D +
Sbjct: 809 CGGELG-DFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLPIEDDCG-DYL 866
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S +S C ++ P S S KL + F+S+ GF ++ +DE
Sbjct: 867 VMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQVPYV-TYDE 923
Score = 51.2 bits (117), Expect = 1e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACG 207
+ T + +EC+ + GC CVNT+G YEC C GY+LH + K C G
Sbjct: 396 YGFTHCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDCVEVKG 447
Score = 50.4 bits (115), Expect = 2e-05
Identities = 17/43 (39%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + + GC H C N +G ++C C G++L +D K C++
Sbjct: 322 KDIDECQTRNGGCDHFCKNIVGSFDCGCKKGFKLLTDEKSCQD 364
Score = 47.6 bits (108), Expect = 1e-04
Identities = 17/40 (42%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC H+CVN +G YEC C G+ L + C
Sbjct: 128 DVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 45.6 bits (103), Expect = 5e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 115 DSMDSPLIGMFCGHKIPPDIRSTSNK---LLVIFESDSTVQKAGFSATFMKEFDE-CASI 170
D+ D P +K+ D RS + +L + ES++T G + E CA
Sbjct: 230 DTADGPECSCHPQYKMHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVN 289
Query: 171 DHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ GC +C +T G C+C +G+ L DGK C++
Sbjct: 290 NGGCDRTCKDTSTGVHCSCPVGFTLQLDGKTCKD 323
Score = 45.2 bits (102), Expect = 7e-04
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 7/127 (5%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMY 259
+C+N CGG L G I SP++P YP C W I PP+ RI + L
Sbjct: 803 QCKNRRCGGELGDFTGYIESPNYPGNYPANTECTWTINPPPKRRILIVVPEIFLP----I 858
Query: 260 QQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ +C D + + ++ + + P TS L +QF S+ GF V
Sbjct: 859 EDDCG-DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGF-QV 916
Query: 320 YYIDVDE 326
Y+ DE
Sbjct: 917 PYVTYDE 923
Score = 44.4 bits (100), Expect = 0.001
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECAS-IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + ++ GC H C+N G Y C C G+ L DG C
Sbjct: 85 EDIDECGNELNGGCVHDCLNIPGNYRCTCFDGFMLAHDGHNC 126
Score = 44.0 bits (99), Expect = 0.002
Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S+D C HSC+N G + CAC+ GY L+
Sbjct: 363 QDVDEC-SLDRTCDHSCINHPGTFACACNRGYTLY 396
Score = 42.3 bits (95), Expect = 0.005
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 10/81 (12%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCKHDVTLPH 375
DVDEC+ + C H C N G + CAC+ G+TL+ H +C GGC+
Sbjct: 364 DVDECSLDRT-CDHSCINHPGTFACACNRGYTLYGFTHCGDTNECSINNGGCQQVCVNTV 422
Query: 376 GTIFSPNYPA--AYPARKDCV 394
G+ +P + +KDCV
Sbjct: 423 GSYECQCHPGYKLHWNKKDCV 443
Score = 37.5 bits (83), Expect = 0.14
Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCE--NACGGAL 210
G +A ++ DECA C C NT Y+C+C GY+ +G++CE + CG L
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQ--GEGRQCEDIDECGNEL 94
Query: 211 YG 212
G
Sbjct: 95 NG 96
Score = 36.7 bits (81), Expect = 0.25
Identities = 24/65 (36%), Positives = 30/65 (46%), Gaps = 9/65 (13%)
Query: 315 GFAAVYYIDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNK-HDCKE------G 365
G AA DVDECA+ C + C NT Y+C+C G+ + D E G
Sbjct: 37 GRAAGPQEDVDECAQGLDDCHADALCQNTPTSYKCSCKPGYQGEGRQCEDIDECGNELNG 96
Query: 366 GCKHD 370
GC HD
Sbjct: 97 GCVHD 101
Score = 31.5 bits (68), Expect = 9.5
Identities = 25/115 (21%), Positives = 42/115 (36%), Gaps = 6/115 (5%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L + Y N Y + +C W I P + + L E +C
Sbjct: 809 CGGELG---DFTGYIESPNYPGN-YPANTECTWTINPPPKRRILIVVPEIFLPIEDDCG- 863
Query: 540 DYVQVFXXXXXXXXXXXTFC-GIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
DY+ + C + P S S+ L ++F++++ +GF Y
Sbjct: 864 DYLVMRKTSSSNSVTTYETCQTYERPIAFTSRSKKLWIQFKSNEGNSARGFQVPY 918
>AB041736-1|BAB40970.1| 1024|Homo sapiens SEZ6L protein.
Length = 1024
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 448 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 501
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 502 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 558
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 559 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 618
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 619 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 678
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 679 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 720
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 438 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 497
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 498 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 552
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 553 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 612
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 613 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 672
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 673 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 721
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 722 AGLIFGKGQGFIMNYIEVSRNDSCSD 747
>AB023144-1|BAA76771.2| 1001|Homo sapiens KIAA0927 protein protein.
Length = 1001
Score = 70.5 bits (165), Expect = 2e-11
Identities = 73/287 (25%), Positives = 116/287 (40%), Gaps = 38/287 (13%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C CGGA++ G + SPS+PE + C+W I AP ++ L+F L
Sbjct: 500 CSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFERLLLH------ 553
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
+ D +TVHS + + ++P + S+G+ +R++FTSD + S F
Sbjct: 554 ---DKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAASTFNIR 610
Query: 320 Y-YIDVDECAE---NNGG--CQHECHNTLGGYECACHSGFTLH-------------PNKH 360
+ + C E NG +N E C G +L P +
Sbjct: 611 FEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWN 670
Query: 361 DCK---EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
D + C +++ G + SPN+P Y +DC+W+ RI L L
Sbjct: 671 DTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQFLNLSNS 730
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSD 464
D +TIYDG LG + G+ P + +S + + F SD
Sbjct: 731 -----DILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSD 772
Score = 68.9 bits (161), Expect = 5e-11
Identities = 83/326 (25%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 37 KPHRGFRA-FYEAVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHS 95
KPH + A CGG + + G + SP+YP++ ++ CIW + P+ ++ L F
Sbjct: 490 KPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFCIWTIEAPEGQKLHLHFER 549
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLI-GMFCGHKIP-PDIRSTSNKLLVIFESDSTVQK 153
+ HD D++ V G + S L+ +P + S N + + F SD
Sbjct: 550 LLL--HDK---DRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGNTIRIEFTSDQARAA 604
Query: 154 AGFSATFMK-EFDECAS--IDHG---CSHSCVNTLGGYECACDIGYELH----------- 196
+ F+ F E C I +G S N E CD G+ L
Sbjct: 605 STFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINV 664
Query: 197 -----SDGKK-CENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTH 250
+D + C CGG L G + SP++PE Y ++C+W+I + RI L+
Sbjct: 665 RDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKIHVGEEKRIFLDIQF 724
Query: 251 FDLEGNHMYQQECEYDSVTVHSKLGADVLRR-HGAFCGTALPPPVTSDGSVLRVQFTSD- 308
+L + D +T++ G +V+ G + G + P + S L +QF SD
Sbjct: 725 LNLSNS---------DILTIYD--GDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFHSDP 773
Query: 309 -GSVHRSGFAAVY-YIDV---DECAE 329
G + G + YI+V D C++
Sbjct: 774 AGLIFGKGQGFIMNYIEVSRNDSCSD 799
>Z99756-1|CAI18854.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP1-100N22 on chromosome 22q13.31-13.33. ).
Length = 988
Score = 70.1 bits (164), Expect = 2e-11
Identities = 26/41 (63%), Positives = 30/41 (73%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC +NNGGCQ C N +G YEC CHSGF L N+H C
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D++EC NNGGC H C NT+G +EC C G+ L ++ C++ C + T H I SP
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSP 341
Score = 57.2 bits (132), Expect = 2e-07
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGG 366
DVDEC+ +NG C C NT G YEC C G LH N DC E G
Sbjct: 362 DVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETG 405
Score = 56.0 bits (129), Expect = 4e-07
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N CK C ++ G I SPNYP YPA +CVW + P RI ++ L
Sbjct: 789 NVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIE 848
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
EC D + + AS T C + + P + ++++ FKS+ KGF +
Sbjct: 849 DECG-DVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
Query: 477 STACGGYLSATEEV 490
T Y E++
Sbjct: 908 VTYDEDYQQLIEDI 921
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ D G++ESPNYP DY N C+W ++ P ++ + + D C D +
Sbjct: 798 CGGELG-DYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECG-DVL 855
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P S S KL + F+S+ GF ++ +DE
Sbjct: 856 VMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYV-TYDE 912
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC C +T G C+C GFTL P+ CK+ GGC H
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH 295
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 323 DVDECAEN--NGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC + NGGC HEC N G Y C C GF L + H+C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 51.6 bits (118), Expect = 8e-06
Identities = 20/47 (42%), Positives = 25/47 (53%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ T + DEC+ + C CVNT G YEC C G LH +GK C
Sbjct: 355 YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDC 401
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ +EC + GC H C NT+G +EC C GY+L +D + C++
Sbjct: 281 KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Score = 48.0 bits (109), Expect = 1e-04
Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 9/127 (7%)
Query: 202 CENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C+N CGG L G I SP++P YP C+W I PP+ RI + L +
Sbjct: 793 CKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLP----IE 848
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGT-ALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
EC V V K + C T P TS L +QF S+ GF V
Sbjct: 849 DEC--GDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGF-QV 905
Query: 320 YYIDVDE 326
Y+ DE
Sbjct: 906 PYVTYDE 912
Score = 45.6 bits (103), Expect = 5e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH + LH + C E
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE 243
Score = 43.6 bits (98), Expect = 0.002
Identities = 17/34 (50%), Positives = 19/34 (55%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC HSC +T G C C Y LHSDG+ C C
Sbjct: 212 GCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETC 245
Score = 43.6 bits (98), Expect = 0.002
Identities = 15/40 (37%), Positives = 24/40 (60%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC +C +T G C+C +G+ L DGK C++
Sbjct: 243 ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKD 282
Score = 43.2 bits (97), Expect = 0.003
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC CVN +G YEC C G+ L + C
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 43.2 bits (97), Expect = 0.003
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENAC----GGALYGPNGTITSPS 221
C + DHGC+H C T GG C C G++L + K C C GG + T T P+
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPT 225
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 162 KEFDECAS--IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + GC H C+N G Y C C G+ L DG C
Sbjct: 73 EDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 41.5 bits (93), Expect = 0.009
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C + GC H C T GG C C GF L N+ DC GGC+H
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH 215
Score = 41.1 bits (92), Expect = 0.012
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH 360
D+DEC+ C H C N+ G ++C CH G+ L+ H
Sbjct: 323 DIDECSFERT-CDHICINSPGSFQCLCHRGYILYGTTH 359
Score = 39.1 bits (87), Expect = 0.047
Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S + C H C+N+ G ++C C GY L+
Sbjct: 322 QDIDEC-SFERTCDHICINSPGSFQCLCHRGYILY 355
Score = 37.9 bits (84), Expect = 0.11
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGF--------TLHPNKHDCKEGGCKHD- 370
+DVDEC+E C + C NT Y+C C G+ + ++D GGC H+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 371 VTLP 374
+ +P
Sbjct: 92 INIP 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 163 EFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DEC+ C C NT Y+C C GY+ +GK+CE+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74
Score = 31.9 bits (69), Expect = 7.2
Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 4/114 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L + ++ S GD Y + A+C W+I P + + L E C
Sbjct: 798 CGGELG--DYTGYIESPNYPGD--YPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGD 853
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
V T + P S S L ++F++++ KGF Y
Sbjct: 854 VLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
>Z82214-3|CAI21674.1| 988|Homo sapiens protein ( Human DNA sequence
from clone RP3-526I14 on chromosome 22. ).
Length = 988
Score = 70.1 bits (164), Expect = 2e-11
Identities = 26/41 (63%), Positives = 30/41 (73%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC +NNGGCQ C N +G YEC CHSGF L N+H C
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D++EC NNGGC H C NT+G +EC C G+ L ++ C++ C + T H I SP
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSP 341
Score = 57.2 bits (132), Expect = 2e-07
Identities = 24/44 (54%), Positives = 26/44 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGG 366
DVDEC+ +NG C C NT G YEC C G LH N DC E G
Sbjct: 362 DVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDCVETG 405
Score = 56.0 bits (129), Expect = 4e-07
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N CK C ++ G I SPNYP YPA +CVW + P RI ++ L
Sbjct: 789 NVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIE 848
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
EC D + + AS T C + + P + ++++ FKS+ KGF +
Sbjct: 849 DECG-DVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
Query: 477 STACGGYLSATEEV 490
T Y E++
Sbjct: 908 VTYDEDYQQLIEDI 921
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ D G++ESPNYP DY N C+W ++ P ++ + + D C D +
Sbjct: 798 CGGELG-DYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECG-DVL 855
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P S S KL + F+S+ GF ++ +DE
Sbjct: 856 VMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYV-TYDE 912
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC C +T G C+C GFTL P+ CK+ GGC H
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH 295
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 323 DVDECAEN--NGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC + NGGC HEC N G Y C C GF L + H+C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 51.6 bits (118), Expect = 8e-06
Identities = 20/47 (42%), Positives = 25/47 (53%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ T + DEC+ + C CVNT G YEC C G LH +GK C
Sbjct: 355 YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNGKDC 401
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ +EC + GC H C NT+G +EC C GY+L +D + C++
Sbjct: 281 KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Score = 48.0 bits (109), Expect = 1e-04
Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 9/127 (7%)
Query: 202 CENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C+N CGG L G I SP++P YP C+W I PP+ RI + L +
Sbjct: 793 CKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLP----IE 848
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGT-ALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
EC V V K + C T P TS L +QF S+ GF V
Sbjct: 849 DEC--GDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGF-QV 905
Query: 320 YYIDVDE 326
Y+ DE
Sbjct: 906 PYVTYDE 912
Score = 45.6 bits (103), Expect = 5e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH + LH + C E
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE 243
Score = 43.6 bits (98), Expect = 0.002
Identities = 17/34 (50%), Positives = 19/34 (55%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC HSC +T G C C Y LHSDG+ C C
Sbjct: 212 GCQHSCEDTDTGPTCGCHQKYALHSDGRTCIETC 245
Score = 43.6 bits (98), Expect = 0.002
Identities = 15/40 (37%), Positives = 24/40 (60%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC +C +T G C+C +G+ L DGK C++
Sbjct: 243 ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKD 282
Score = 43.2 bits (97), Expect = 0.003
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC CVN +G YEC C G+ L + C
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 43.2 bits (97), Expect = 0.003
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENAC----GGALYGPNGTITSPS 221
C + DHGC+H C T GG C C G++L + K C C GG + T T P+
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPT 225
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 162 KEFDECAS--IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + GC H C+N G Y C C G+ L DG C
Sbjct: 73 EDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 41.5 bits (93), Expect = 0.009
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C + GC H C T GG C C GF L N+ DC GGC+H
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH 215
Score = 41.1 bits (92), Expect = 0.012
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH 360
D+DEC+ C H C N+ G ++C CH G+ L+ H
Sbjct: 323 DIDECSFERT-CDHICINSPGSFQCLCHRGYILYGTTH 359
Score = 39.1 bits (87), Expect = 0.047
Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S + C H C+N+ G ++C C GY L+
Sbjct: 322 QDIDEC-SFERTCDHICINSPGSFQCLCHRGYILY 355
Score = 37.9 bits (84), Expect = 0.11
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGF--------TLHPNKHDCKEGGCKHD- 370
+DVDEC+E C + C NT Y+C C G+ + ++D GGC H+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 371 VTLP 374
+ +P
Sbjct: 92 INIP 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 163 EFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DEC+ C C NT Y+C C GY+ +GK+CE+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74
Score = 31.9 bits (69), Expect = 7.2
Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 4/114 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L + ++ S GD Y + A+C W+I P + + L E C
Sbjct: 798 CGGELG--DYTGYIESPNYPGD--YPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGD 853
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
V T + P S S L ++F++++ KGF Y
Sbjct: 854 VLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
>BC127263-1|AAI27264.1| 363|Homo sapiens SCUBE1 protein protein.
Length = 363
Score = 70.1 bits (164), Expect = 2e-11
Identities = 26/41 (63%), Positives = 30/41 (73%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC +NNGGCQ C N +G YEC CHSGF L N+H C
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D++EC NNGGC H C NT+G +EC C G+ L ++ C++ C + T H I SP
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSP 341
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC C +T G C+C GFTL P+ CK+ GGC H
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH 295
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 323 DVDECAEN--NGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC + NGGC HEC N G Y C C GF L + H+C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ +EC + GC H C NT+G +EC C GY+L +D + C++
Sbjct: 281 KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Score = 45.2 bits (102), Expect = 7e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH + LH + C E
Sbjct: 206 CNYGNGGCQHSCEDTDTGPMCGCHQKYALHSDGRTCIE 243
Score = 43.6 bits (98), Expect = 0.002
Identities = 15/40 (37%), Positives = 24/40 (60%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC +C +T G C+C +G+ L DGK C++
Sbjct: 243 ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKD 282
Score = 43.2 bits (97), Expect = 0.003
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC CVN +G YEC C G+ L + C
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 43.2 bits (97), Expect = 0.003
Identities = 17/34 (50%), Positives = 19/34 (55%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC HSC +T G C C Y LHSDG+ C C
Sbjct: 212 GCQHSCEDTDTGPMCGCHQKYALHSDGRTCIETC 245
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 162 KEFDECAS--IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + GC H C+N G Y C C G+ L DG C
Sbjct: 73 EDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 42.7 bits (96), Expect = 0.004
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENAC----GGALYGPNGTITSP 220
C + DHGC+H C T GG C C G++L + K C C GG + T T P
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGP 224
Score = 41.5 bits (93), Expect = 0.009
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C + GC H C T GG C C GF L N+ DC GGC+H
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH 215
Score = 37.9 bits (84), Expect = 0.11
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGF--------TLHPNKHDCKEGGCKHD- 370
+DVDEC+E C + C NT Y+C C G+ + ++D GGC H+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 371 VTLP 374
+ +P
Sbjct: 92 INIP 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 163 EFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DEC+ C C NT Y+C C GY+ +GK+CE+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74
>BC047916-1|AAH47916.1| 347|Homo sapiens SCUBE1 protein protein.
Length = 347
Score = 70.1 bits (164), Expect = 2e-11
Identities = 26/41 (63%), Positives = 30/41 (73%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC +NNGGCQ C N +G YEC CHSGF L N+H C
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 67.7 bits (158), Expect = 1e-10
Identities = 60/214 (28%), Positives = 80/214 (37%), Gaps = 32/214 (14%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ DEC + GC CVN +G YEC C G+ L + C + + N
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKD------ 170
Query: 223 PELYPPLKNCLWEIVAPPQHRITLNFTH-FDLEGNHM-YQQECEY-DSVTVHSKLGADVL 279
C P+ + + FDL N C Y + HS D
Sbjct: 171 -------HGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDT- 222
Query: 280 RRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE----------CAE 329
G CG + SDG + + ++ RS F A DVD+ CA
Sbjct: 223 ---GPTCGCHQKYALHSDGRTCIEK--DEAAIERSQFNATSVADVDKRVKRRLLMETCAV 277
Query: 330 NNGGCQHECHNTLGGYECACHSGFTLHPNKHDCK 363
NNGGC C +T G C+C GFTL P+ CK
Sbjct: 278 NNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCK 311
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 323 DVDECAEN--NGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC + NGGC HEC N G Y C C GF L + H+C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 45.6 bits (103), Expect = 5e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH + LH + C E
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYALHSDGRTCIE 243
Score = 44.4 bits (100), Expect = 0.001
Identities = 20/70 (28%), Positives = 38/70 (54%), Gaps = 10/70 (14%)
Query: 144 IFESDSTVQKAGFSATFMKEFDE----------CASIDHGCSHSCVNTLGGYECACDIGY 193
I + ++ ++++ F+AT + + D+ CA + GC +C +T G C+C +G+
Sbjct: 242 IEKDEAAIERSQFNATSVADVDKRVKRRLLMETCAVNNGGCDRTCKDTATGVRCSCPVGF 301
Query: 194 ELHSDGKKCE 203
L DGK C+
Sbjct: 302 TLQPDGKTCK 311
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 162 KEFDECAS--IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + GC H C+N G Y C C G+ L DG C
Sbjct: 73 EDIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 41.5 bits (93), Expect = 0.009
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C + GC H C T GG C C GF L N+ DC GGC+H
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH 215
Score = 37.9 bits (84), Expect = 0.11
Identities = 20/64 (31%), Positives = 31/64 (48%), Gaps = 11/64 (17%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGF--------TLHPNKHDCKEGGCKHD- 370
+DVDEC+E C + C NT Y+C C G+ + ++D GGC H+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYKGEGKQCEDIDECENDYYNGGCVHEC 91
Query: 371 VTLP 374
+ +P
Sbjct: 92 INIP 95
Score = 32.7 bits (71), Expect = 4.1
Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 4/44 (9%)
Query: 163 EFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DEC+ C C NT Y+C C GY+ +GK+CE+
Sbjct: 33 DVDECSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGKQCED 74
>AF525689-1|AAN77133.1| 988|Homo sapiens signal
peptide-CUB-EGF-like domain containing protein 1
protein.
Length = 988
Score = 70.1 bits (164), Expect = 2e-11
Identities = 26/41 (63%), Positives = 30/41 (73%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC +NNGGCQ C N +G YEC CHSGF L N+H C
Sbjct: 116 LDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 62.1 bits (144), Expect = 6e-09
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D++EC NNGGC H C NT+G +EC C G+ L ++ C++ C + T H I SP
Sbjct: 282 DINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQDIDECSFERTCDHICINSP 341
Score = 58.8 bits (136), Expect = 5e-08
Identities = 24/44 (54%), Positives = 27/44 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGG 366
DVDEC+ +NG C C NT G YEC C G LH N+ DC E G
Sbjct: 362 DVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDCVETG 405
Score = 56.0 bits (129), Expect = 4e-07
Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 2/134 (1%)
Query: 358 NKHDCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N CK C ++ G I SPNYP YPA +CVW + P RI ++ L
Sbjct: 789 NVTHCKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIE 848
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGS-KLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
EC D + + AS T C + + P + ++++ FKS+ KGF +
Sbjct: 849 DECG-DVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
Query: 477 STACGGYLSATEEV 490
T Y E++
Sbjct: 908 VTYDEDYQQLIEDI 921
Score = 55.2 bits (127), Expect = 7e-07
Identities = 35/118 (29%), Positives = 56/118 (47%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ D G++ESPNYP DY N C+W ++ P ++ + + D C D +
Sbjct: 798 CGGELG-DYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLPIEDECG-DVL 855
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P S S KL + F+S+ GF ++ +DE
Sbjct: 856 VMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPYV-TYDE 912
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC C +T G C+C GFTL P+ CK+ GGC H
Sbjct: 242 IETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKDINECLVNNGGCDH 295
Score = 52.4 bits (120), Expect = 5e-06
Identities = 21/42 (50%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 323 DVDECAEN--NGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC + NGGC HEC N G Y C C GF L + H+C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ +EC + GC H C NT+G +EC C GY+L +D + C++
Sbjct: 281 KDINECLVNNGGCDHFCRNTVGSFECGCRKGYKLLTDERTCQD 323
Score = 48.4 bits (110), Expect = 8e-05
Identities = 19/47 (40%), Positives = 24/47 (51%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ T + DEC+ + C CVNT G YEC C G LH + K C
Sbjct: 355 YGTTHCGDVDECSMSNGSCDQGCVNTKGSYECVCPPGRRLHWNRKDC 401
Score = 48.0 bits (109), Expect = 1e-04
Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 9/127 (7%)
Query: 202 CENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C+N CGG L G I SP++P YP C+W I PP+ RI + L +
Sbjct: 793 CKNQHCGGELGDYTGYIESPNYPGDYPANAECVWHIAPPPKRRILIVVPEIFLP----IE 848
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGT-ALPPPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
EC V V K + C T P TS L +QF S+ GF V
Sbjct: 849 DEC--GDVLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGF-QV 905
Query: 320 YYIDVDE 326
Y+ DE
Sbjct: 906 PYVTYDE 912
Score = 43.6 bits (98), Expect = 0.002
Identities = 15/40 (37%), Positives = 24/40 (60%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC +C +T G C+C +G+ L DGK C++
Sbjct: 243 ETCAVNNGGCDRTCKDTATGVRCSCPVGFTLQPDGKTCKD 282
Score = 43.2 bits (97), Expect = 0.003
Identities = 16/40 (40%), Positives = 21/40 (52%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + GC CVN +G YEC C G+ L + C
Sbjct: 117 DVDECQDNNGGCQQICVNAMGSYECQCHSGFFLSDNQHTC 156
Score = 43.2 bits (97), Expect = 0.003
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENAC----GGALYGPNGTITSPS 221
C + DHGC+H C T GG C C G++L + K C C GG + T T P+
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSCEDTDTGPT 225
Score = 42.7 bits (96), Expect = 0.004
Identities = 16/38 (42%), Positives = 19/38 (50%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH + H + C E
Sbjct: 206 CNYGNGGCQHSCEDTDTGPTCGCHQKYAPHSDGRTCIE 243
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 2/42 (4%)
Query: 163 EFDECAS--IDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + GC H C+N G Y C C G+ L DG C
Sbjct: 74 DIDECENDYYNGGCVHECINIPGNYRCTCFDGFMLAHDGHNC 115
Score = 41.5 bits (93), Expect = 0.009
Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C + GC H C T GG C C GF L N+ DC GGC+H
Sbjct: 166 CMNKDHGCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQH 215
Score = 41.1 bits (92), Expect = 0.012
Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH 360
D+DEC+ C H C N+ G ++C CH G+ L+ H
Sbjct: 323 DIDECSFERT-CDHICINSPGSFQCLCHRGYILYGTTH 359
Score = 40.7 bits (91), Expect = 0.015
Identities = 16/34 (47%), Positives = 18/34 (52%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC HSC +T G C C Y HSDG+ C C
Sbjct: 212 GCQHSCEDTDTGPTCGCHQKYAPHSDGRTCIETC 245
Score = 39.1 bits (87), Expect = 0.047
Identities = 14/35 (40%), Positives = 22/35 (62%), Gaps = 1/35 (2%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH 196
++ DEC S + C H C+N+ G ++C C GY L+
Sbjct: 322 QDIDEC-SFERTCDHICINSPGSFQCLCHRGYILY 355
Score = 35.9 bits (79), Expect = 0.44
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 11/64 (17%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGF--------TLHPNKHDCKEGGCKHD- 370
+DVDEC+E C + C N Y+C C G+ + ++D GGC H+
Sbjct: 32 VDVDECSEGTDDCHIDAICQNAPKSYKCLCKPGYKGEGKQCGDIDECENDYYNGGCVHEC 91
Query: 371 VTLP 374
+ +P
Sbjct: 92 INIP 95
Score = 31.9 bits (69), Expect = 7.2
Identities = 27/114 (23%), Positives = 42/114 (36%), Gaps = 4/114 (3%)
Query: 480 CGGYLSATEEVKHLYSHARYGDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRY 539
CGG L + ++ S GD Y + A+C W+I P + + L E C
Sbjct: 798 CGGELG--DYTGYIESPNYPGD--YPANAECVWHIAPPPKRRILIVVPEIFLPIEDECGD 853
Query: 540 DYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
V T + P S S L ++F++++ KGF Y
Sbjct: 854 VLVMRKSASPTSITTYETCQTYERPIAFTSRSRKLWIQFKSNEGNSGKGFQVPY 907
>U03272-1|AAA18950.1| 2911|Homo sapiens fibrillin-2 protein.
Length = 2911
Score = 68.9 bits (161), Expect = 5e-11
Identities = 71/257 (27%), Positives = 101/257 (39%), Gaps = 26/257 (10%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NAC-GGALYGPNGTITS 219
+ DEC ++ GC C N+ G YEC+C GY L DG+ C + C G T
Sbjct: 1241 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT- 1299
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE--YDSVTVHSKLGAD 277
+ P Y L C +A + ++ DL N ECE S H +LG
Sbjct: 1300 -NIPGEYRCL--CYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS 1356
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQ-FTSDGSVH---RSGFA--AVYYIDVDECAENN 331
V ++ C + + + GS R G+ + ID+DEC+
Sbjct: 1357 V-KKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGT 1415
Query: 332 GGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAY 387
C +C NT G Y CAC GFT + C + C ++ L +G N P AY
Sbjct: 1416 HQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCL--NVPGAY 1471
Query: 388 PARKDCVWQFSTTPGHR 404
R +C F+ R
Sbjct: 1472 --RCECEMGFTPASDSR 1486
Score = 60.9 bits (141), Expect = 1e-08
Identities = 55/208 (26%), Positives = 79/208 (37%), Gaps = 10/208 (4%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNG-TIT 218
++ DEC+ + S +C N G + C CD GYEL G C + C + NG +
Sbjct: 1489 QDIDECSFQNICVSGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVN 1548
Query: 219 SPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGAD 277
+P E PP V +R+ + F G+ E S
Sbjct: 1549 TPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS 1608
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQ-H 336
+ + G C T PPV S G R + D+DEC E G CQ
Sbjct: 1609 LGKAWGNPCETC--PPV---NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGG 1663
Query: 337 ECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NT G ++C C G+ L + C++
Sbjct: 1664 NCINTFGSFQCECPQGYYLSEDTRICED 1691
Score = 60.5 bits (140), Expect = 2e-08
Identities = 68/259 (26%), Positives = 112/259 (43%), Gaps = 38/259 (14%)
Query: 161 MKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITS 219
+++ DEC + C +C+NT G ++C C GY L D + CE+ + G +
Sbjct: 1647 LEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI--DECFAHPG-VCG 1703
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTH--FDLEGNHMYQQECEYDSVTVHSKLGAD 277
P Y L N + + PP++ + +N H D+ + Y+ Y+ T ++L +
Sbjct: 1704 PG--TCYNTLGN--YTCICPPEY-MQVNGGHNCMDMRKSFCYRS---YNGTTCENELPFN 1755
Query: 278 VLRRHGAFC---GTA-------LPPPVTSDGSVLRVQ---FTSDGSVHRSGFAAVYYIDV 324
V +R G A P P T+D + FT D +H +G A +D+
Sbjct: 1756 VTKRMCCCTYNVGKAGNKPCEPCPTPGTADFKTICGNIPGFTFD--IH-TGKA----VDI 1808
Query: 325 DECAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPN 382
DEC E G C + C N +G + C C +GF+ + C++ C + L N
Sbjct: 1809 DECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCIN 1868
Query: 383 YPAAYPARKDCVWQFSTTP 401
P +Y R +C F +P
Sbjct: 1869 SPGSY--RCECAAGFKLSP 1885
Score = 54.0 bits (124), Expect = 2e-06
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC-ENACGGALYGPNGTITSPSF 222
+EC + C + CVN +G Y C C+ G++ S G +C +N G TI +
Sbjct: 2339 NECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMAS 2398
Query: 223 PELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRR 281
K+ C + H+ L L G Y++ C + D +
Sbjct: 2399 SSRNLVTKSECCCDGGRGWGHQCEL----CPLPGTAQYKKICPHGPGYTTDGRDIDECKV 2454
Query: 282 HGAFCGTA-LPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C + S +V +T+D SG + + D+DEC+++ C + C N
Sbjct: 2455 MPNLCTNGQCINTMGSFRCFCKVGYTTD----ISGTSCI---DLDECSQSPKPCNYICKN 2507
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G Y+C+C G+ L + CK+
Sbjct: 2508 TEGSYQCSCPRGYVLQEDGKTCKD 2531
Score = 51.2 bits (117), Expect = 1e-05
Identities = 20/48 (41%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
S T + DEC+ C++ C NT G Y+C+C GY L DGK C++
Sbjct: 2484 SGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD 2531
Score = 50.8 bits (116), Expect = 1e-05
Identities = 20/46 (43%), Positives = 24/46 (52%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACG 207
K+ DEC + H C CVNTLGG+ C C G+ H N CG
Sbjct: 2530 KDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECG 2575
Score = 50.4 bits (115), Expect = 2e-05
Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC-KEGGCKH 369
DVDEC + N CQH C N LGGY C C G+ H + C E C +
Sbjct: 2613 DVDEC-DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSN 2659
Score = 49.2 bits (112), Expect = 4e-05
Identities = 19/43 (44%), Positives = 26/43 (60%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ +ECA C+ C+NT G YEC C IGY L D K C++
Sbjct: 2251 EDINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKD 2293
Score = 48.4 bits (110), Expect = 8e-05
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC +H C H C N LGGY C C GY H +C EN C
Sbjct: 2612 EDVDECDG-NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENEC 2657
Score = 48.0 bits (109), Expect = 1e-04
Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 13/200 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ +EC + C SC NT GG++C C G+ L +G++C + + N S
Sbjct: 2055 DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF-TNFENGKCS 2113
Query: 222 FPELYPPLK-NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C + D E +Q C Y TV S R
Sbjct: 2114 VPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDE--VAFQDLCPYGHGTVPS---LHDTR 2168
Query: 281 RHGAFCGTALPPPVTSDGSVLRV--QFTSDGSV-HRSGFAAVYYIDVDECAENNGGCQHE 337
C + P + S+G + F + + + + V +D DEC+ N
Sbjct: 2169 EDVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT 2226
Query: 338 CHNTLGGYECACHSGFTLHP 357
C N +G +EC C+ GF P
Sbjct: 2227 CTNVIGSFECNCNEGFEPGP 2246
Score = 47.2 bits (107), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D++ECA+N C C NT G YEC C G+ L ++ CK+
Sbjct: 2252 DINECAQNPLLCALRCMNTFGSYECTCPIGYALREDQKMCKD 2293
Score = 46.8 bits (106), Expect = 2e-04
Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 320 YYIDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+Y D++EC G C + +C NT+G ++C C+SGF L + +C +
Sbjct: 1069 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 1114
Score = 46.4 bits (105), Expect = 3e-04
Identities = 18/34 (52%), Positives = 20/34 (58%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NTLGG+ C C GFT H
Sbjct: 2531 DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH 2564
Score = 45.6 bits (103), Expect = 5e-04
Identities = 50/212 (23%), Positives = 78/212 (36%), Gaps = 21/212 (9%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-ENACGGALYG--PNGT 216
+ + DEC + + C+N+ G + C C G + DG+ C + YG G
Sbjct: 654 YCTDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGV 713
Query: 217 ITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGA 276
P FP + C A P + + + + C S +G
Sbjct: 714 CVRP-FPGAVTKSECCC----ANPDYGFGEPCQPCPAKNSAEFHGLCS-------SGVGI 761
Query: 277 DVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSD-GSVHRSGFAAVYYIDVDECAENNGG 333
V R C AL P + ++G LR + + S + + ID+DEC N
Sbjct: 762 TVDGRDINEC--ALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLL 819
Query: 334 CQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C NT G Y C C G+ C++
Sbjct: 820 CDNGLCRNTPGSYSCTCPPGYVFRTETETCED 851
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDECAEN C++ +C N G Y C C GFT + C++
Sbjct: 1448 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQD 1490
Score = 45.2 bits (102), Expect = 7e-04
Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC N C + +C NT G Y C CH+GF P K C
Sbjct: 533 IDVDECTSNP--CTNGDCVNTPGSYYCKCHAGFQRTPTKQAC 572
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 5/54 (9%)
Query: 154 AGFSATFMKE----FDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
AGF T K+ DEC C + CVN+ G ++C C+ G+EL +DGK C
Sbjct: 561 AGFQRTPTKQACIDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNC 614
Score = 43.6 bits (98), Expect = 0.002
Identities = 17/43 (39%), Positives = 24/43 (55%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +EC+ N C+NTLG Y+CAC SGF+ C +
Sbjct: 2652 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 2694
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHPN 358
D+DEC+ + CQ +C N+ G Y C C +GF L PN
Sbjct: 1849 DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN 1886
Score = 42.3 bits (95), Expect = 0.005
Identities = 54/215 (25%), Positives = 74/215 (34%), Gaps = 21/215 (9%)
Query: 163 EFDECASIDHGC-SHSCVNTLGGYECACDIGYELH-------SDGKKCEN---AC-GGAL 210
+ DEC C S CVNT G +EC C GYE D CE C GG
Sbjct: 1114 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTC 1173
Query: 211 YGPNGTI--TSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
G+ P EL P ++C+ + N ++ G YQ C
Sbjct: 1174 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGT--YQCSCNPGYQ 1231
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECA 328
+ G + G S+GS + ++ G + D+DEC
Sbjct: 1232 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGS-YECSCSEGYALMPDGRSCA---DIDECE 1287
Query: 329 ENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
N C +C N G Y C C+ GF + C
Sbjct: 1288 NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 1322
Score = 42.3 bits (95), Expect = 0.005
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECASI-DHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ DEC+S C + C N +G ++C C+ GYEL DGK C
Sbjct: 1972 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 2013
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 1/44 (2%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC +I C +C+NT+G +EC C G++ +KCE+
Sbjct: 274 QDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 317
Score = 41.5 bits (93), Expect = 0.009
Identities = 13/44 (29%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D++EC+ ++ C++ +C N +G Y+C+C+ G+ P++ C +
Sbjct: 1198 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTD 1241
Score = 41.5 bits (93), Expect = 0.009
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + +Q + H +GF A +DVDEC + G C NT+G Y C
Sbjct: 1899 PNVCSHGLCVDLQGSYQCICH-NGFKASQDQTMCMDVDECERHPCG-NGTCKNTVGSYNC 1956
Query: 348 ACHSGFTLHPNKHDC 362
C+ GF L N +DC
Sbjct: 1957 LCYPGFELTHN-NDC 1970
Score = 41.1 bits (92), Expect = 0.012
Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DEC+ I C + C NT+G Y C C GY +DG +C
Sbjct: 316 EDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 357
Score = 41.1 bits (92), Expect = 0.012
Identities = 16/42 (38%), Positives = 27/42 (64%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC +N C++ C N+ G ++C C++GF L + +C
Sbjct: 573 IDIDECIQNGVLCKNGRCVNSDGSFQCICNAGFELTTDGKNC 614
Score = 41.1 bits (92), Expect = 0.012
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID++EC E+ C C NT GG++C C GF L N C
Sbjct: 2054 IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC 2095
Score = 41.1 bits (92), Expect = 0.012
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + C++ C+NT+G + C C +GY G C
Sbjct: 2447 RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC 2488
Score = 40.3 bits (90), Expect = 0.020
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGP--NGTIT 218
++ +EC CS+ C+NT G + C C +GY L G +C + ++ P NGT T
Sbjct: 2169 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 2228
Query: 219 S 219
+
Sbjct: 2229 N 2229
Score = 40.3 bits (90), Expect = 0.020
Identities = 14/31 (45%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DV+EC+ + C + C NT GGY C C G+
Sbjct: 2694 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2724
Score = 39.5 bits (88), Expect = 0.036
Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 160 FMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
F K+ +EC + C++ C NT+G ++C C+ G+ L + + C
Sbjct: 1069 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 1112
Score = 39.5 bits (88), Expect = 0.036
Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DECA + C + C+N G Y C C++G+ SD + C++
Sbjct: 1448 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQD 1490
Score = 39.1 bits (87), Expect = 0.047
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D+DEC+ G C++ C N +G ++C C+ G+ L P+ +C
Sbjct: 1971 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 2013
Score = 39.1 bits (87), Expect = 0.047
Identities = 14/31 (45%), Positives = 20/31 (64%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGY 193
+ +EC+S + C++ C NT GGY C C GY
Sbjct: 2694 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 2724
Score = 37.9 bits (84), Expect = 0.11
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C NT+G +EC C +G C++
Sbjct: 275 DVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 317
Score = 37.9 bits (84), Expect = 0.11
Identities = 16/43 (37%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D DEC N C N G ++C C GF L PN C +
Sbjct: 615 VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCTD 657
Score = 37.9 bits (84), Expect = 0.11
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGA 209
+EC++ + S SC NTLG Y+CAC G+ C N C +
Sbjct: 2655 NECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSS 2701
Score = 37.5 bits (83), Expect = 0.14
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
D+DEC+ G C+ EC NT+G Y C C G+ + C
Sbjct: 317 DIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRC 357
Score = 37.5 bits (83), Expect = 0.14
Identities = 14/40 (35%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDG 199
++ DEC++ D+ C + C+N+ G Y C C G++L +G
Sbjct: 1848 EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG 1887
Score = 37.5 bits (83), Expect = 0.14
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH CV+ G Y+C C G++ D C
Sbjct: 1893 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMC 1931
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 12/62 (19%)
Query: 322 IDVDECAENNGGCQHE-CHNTLGGYECACHSGFTLHPN-----------KHDCKEGGCKH 369
+D +EC E C H C + G Y+C CH+GF + +H C G CK+
Sbjct: 1890 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKN 1949
Query: 370 DV 371
V
Sbjct: 1950 TV 1951
Score = 36.7 bits (81), Expect = 0.25
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 153 KAGFSATFMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYEL 195
KA T + DEC H C + +C NT+G Y C C G+EL
Sbjct: 1923 KASQDQTMCMDVDECER--HPCGNGTCKNTVGSYNCLCYPGFEL 1964
Score = 36.7 bits (81), Expect = 0.25
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 162 KEFDECASIDHGCSHS---CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
K+ DECA H C C N +G + C C G DG+ C EN C
Sbjct: 2292 KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENEC 2341
Score = 36.7 bits (81), Expect = 0.25
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC---KEGGCKHDV 371
+D +EC G C++ C N +G Y C C+ GF + +C ++G C +V
Sbjct: 2336 VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEV 2389
Score = 35.9 bits (79), Expect = 0.44
Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 323 DVDECAENNGGCQHE---CHNTLGGYECACHSGFTLHPNKHDC-KEGGCK 368
D+DECAE C+ C N +G + C C G P+ C E C+
Sbjct: 2293 DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 2342
Score = 35.5 bits (78), Expect = 0.58
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYELHS----DGKKCENACGGALYGPNGTITS 219
+EC ++ CS +C N G + C C GYE+ S D +C+ L+G + T T
Sbjct: 2017 NECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFG-SCTNTP 2075
Query: 220 PSFPELYPP 228
F L PP
Sbjct: 2076 GGFQCLCPP 2084
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--------CVNTLGGYECACDIGYELHSDGKKC 202
G+ + FM C ID GC + CVNT G ++C C +G+EL + C
Sbjct: 1144 GYESGFMM-MKNCMDID-GCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 1197
Score = 33.9 bits (74), Expect = 1.8
Identities = 12/40 (30%), Positives = 22/40 (55%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + + C+N G ++C C G+ L +G+ C
Sbjct: 616 DHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC 655
Score = 33.1 bits (72), Expect = 3.1
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+EC S C C NT G + C C G+ L + G CE+ C G
Sbjct: 2572 NECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG 2619
Score = 32.7 bits (71), Expect = 4.1
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHG 376
ID +EC C + C NT G + C C GF+L +C++ C + HG
Sbjct: 2569 IDNNECGSQPLLCGGKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG 2626
Score = 32.3 bits (70), Expect = 5.4
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ DEC S + C++ CVNT G Y C C G++ + C
Sbjct: 534 DVDECTS--NPCTNGDCVNTPGSYYCKCHAGFQRTPTKQAC 572
Score = 31.9 bits (69), Expect = 7.2
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 160 FMKEFDECASIDHGCSHSCVN-----TLGGYECACDIGYELHSDGKKCENACGGALY 211
F E + C I+ S+ CVN LG + C C G +L S G C ++ G +
Sbjct: 842 FRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCW 898
Score = 31.9 bits (69), Expect = 7.2
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C N+ G + C C G TL C
Sbjct: 954 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 994
Score = 31.9 bits (69), Expect = 7.2
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 17/87 (19%)
Query: 323 DVDECAENNGGCQHE-CHNTLGGYECAC----HSGFTLHPNKHDCKEGGCKHDVTLPHGT 377
D+DEC + C C NT G +EC C SGF + N D GC+ + L G
Sbjct: 1114 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDI--DGCERNPLLCRGG 1171
Query: 378 I-------FSPNYPAAY---PARKDCV 394
F + P + P+R+DCV
Sbjct: 1172 TCVNTEGSFQCDCPLGHELSPSREDCV 1198
>AB209735-1|BAD92972.1| 1976|Homo sapiens fibrillin 2 (congenital
contractural arachnodactyly) variant protein.
Length = 1976
Score = 68.9 bits (161), Expect = 5e-11
Identities = 71/257 (27%), Positives = 101/257 (39%), Gaps = 26/257 (10%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NAC-GGALYGPNGTITS 219
+ DEC ++ GC C N+ G YEC+C GY L DG+ C + C G T
Sbjct: 306 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT- 364
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE--YDSVTVHSKLGAD 277
+ P Y L C +A + ++ DL N ECE S H +LG
Sbjct: 365 -NIPGEYRCL--CYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS 421
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQ-FTSDGSVH---RSGFA--AVYYIDVDECAENN 331
V ++ C + + + GS R G+ + ID+DEC+
Sbjct: 422 V-KKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGT 480
Query: 332 GGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAY 387
C +C NT G Y CAC GFT + C + C ++ L +G N P AY
Sbjct: 481 HQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCL--NVPGAY 536
Query: 388 PARKDCVWQFSTTPGHR 404
R +C F+ R
Sbjct: 537 --RCECEMGFTPASDSR 551
Score = 60.9 bits (141), Expect = 1e-08
Identities = 64/254 (25%), Positives = 108/254 (42%), Gaps = 28/254 (11%)
Query: 161 MKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITS 219
+++ DEC + C +C+NT G ++C C GY L D + CE+ + G +
Sbjct: 712 LEDIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRICEDI--DECFAHPG-VCG 768
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTH--FDLEGNHMYQQECEYDSVTVHSKLGAD 277
P Y L N + + PP++ + +N H D+ + Y+ Y+ T ++L +
Sbjct: 769 PG--TCYNTLGN--YTCICPPEY-MQVNGGHNCMDMRKSFCYR---SYNGTTCENELPFN 820
Query: 278 VLRRHGAF---CGTALPPPVTSDGSVLRVQF-TSDGSVHRSGFAAVYY----IDVDECAE 329
V +R G A P + F T G++ GF + +D+DEC E
Sbjct: 821 VTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTICGNI--PGFTFDIHTGKAVDIDECKE 878
Query: 330 NNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYPAAY 387
G C + C N +G + C C +GF+ + C++ C + L N P +Y
Sbjct: 879 IPGICANGVCINQIGSFRCECPTGFSYNDLLLVCEDIDECSNGDNLCQRNADCINSPGSY 938
Query: 388 PARKDCVWQFSTTP 401
R +C F +P
Sbjct: 939 --RCECAAGFKLSP 950
Score = 58.4 bits (135), Expect = 7e-08
Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 10/208 (4%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNG-TIT 218
++ DEC+ + +C N G + C CD GYEL G C + C + NG +
Sbjct: 554 QDIDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPINCVNGLCVN 613
Query: 219 SPSFPEL-YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGAD 277
+P E PP V +R+ + F G+ E S
Sbjct: 614 TPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSCCCS 673
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQ-H 336
+ + G C T PPV S G R + D+DEC E G CQ
Sbjct: 674 LGKAWGNPCETC--PPV---NSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGG 728
Query: 337 ECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NT G ++C C G+ L + C++
Sbjct: 729 NCINTFGSFQCECPQGYYLSEDTRICED 756
Score = 54.0 bits (124), Expect = 2e-06
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC-ENACGGALYGPNGTITSPSF 222
+EC + C + CVN +G Y C C+ G++ S G +C +N G TI +
Sbjct: 1404 NECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTICQMAS 1463
Query: 223 PELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRR 281
K+ C + H+ L L G Y++ C + D +
Sbjct: 1464 SSRNLVTKSECCCDGGRGWGHQCEL----CPLPGTAQYKKICPHGPGYTTDGRDIDECKV 1519
Query: 282 HGAFCGTA-LPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C + S +V +T+D SG + + D+DEC+++ C + C N
Sbjct: 1520 MPNLCTNGQCINTMGSFRCFCKVGYTTD----ISGTSCI---DLDECSQSPKPCNYICKN 1572
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G Y+C+C G+ L + CK+
Sbjct: 1573 TEGSYQCSCPRGYVLQEDGKTCKD 1596
Score = 51.2 bits (117), Expect = 1e-05
Identities = 20/48 (41%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
S T + DEC+ C++ C NT G Y+C+C GY L DGK C++
Sbjct: 1549 SGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKD 1596
Score = 51.2 bits (117), Expect = 1e-05
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGG--ALYGPNG 215
K+ DEC + H C CVNTLGG+ C C G+ H N CG +L G G
Sbjct: 1595 KDLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKG 1650
Score = 50.4 bits (115), Expect = 2e-05
Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC-KEGGCKH 369
DVDEC + N CQH C N LGGY C C G+ H + C E C +
Sbjct: 1678 DVDEC-DGNHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENECSN 1724
Score = 50.0 bits (114), Expect = 3e-05
Identities = 19/43 (44%), Positives = 26/43 (60%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ +ECA C+ C+NT G YEC C IGY L D K C++
Sbjct: 1316 EDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKD 1358
Score = 48.4 bits (110), Expect = 8e-05
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC +H C H C N LGGY C C GY H +C EN C
Sbjct: 1677 EDVDECDG-NHRCQHGCQNILGGYRCGCPQGYIQHYQWNQCVDENEC 1722
Score = 48.0 bits (109), Expect = 1e-04
Identities = 49/200 (24%), Positives = 77/200 (38%), Gaps = 13/200 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ +EC + C SC NT GG++C C G+ L +G++C + + N S
Sbjct: 1120 DINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDTRQSFCF-TNFENGKCS 1178
Query: 222 FPELYPPLK-NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C + D E +Q C Y TV S R
Sbjct: 1179 VPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDE--VAFQDLCPYGHGTVPS---LHDTR 1233
Query: 281 RHGAFCGTALPPPVTSDGSVLRV--QFTSDGSV-HRSGFAAVYYIDVDECAENNGGCQHE 337
C + P + S+G + F + + + + V +D DEC+ N
Sbjct: 1234 EDVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGT 1291
Query: 338 CHNTLGGYECACHSGFTLHP 357
C N +G +EC C+ GF P
Sbjct: 1292 CTNVIGSFECNCNEGFEPGP 1311
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D++ECA+N C C NT G YEC C G+ L ++ CK+
Sbjct: 1317 DINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKD 1358
Score = 46.8 bits (106), Expect = 2e-04
Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 320 YYIDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+Y D++EC G C + +C NT+G ++C C+SGF L + +C +
Sbjct: 134 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 179
Score = 46.4 bits (105), Expect = 3e-04
Identities = 18/34 (52%), Positives = 20/34 (58%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NTLGG+ C C GFT H
Sbjct: 1596 DLDECQTKQHNCQFLCVNTLGGFTCKCPPGFTQH 1629
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/43 (44%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDECAEN C++ +C N G Y C C GFT + C++
Sbjct: 513 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQD 555
Score = 43.6 bits (98), Expect = 0.002
Identities = 54/215 (25%), Positives = 75/215 (34%), Gaps = 21/215 (9%)
Query: 163 EFDECASIDHGC-SHSCVNTLGGYECACDIGYELH-------SDGKKCEN---AC-GGAL 210
+ DEC C S CVNT G +EC C GYE D +CE C GG
Sbjct: 179 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPLLCRGGTC 238
Query: 211 YGPNGTI--TSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
G+ P EL P ++C+ + N ++ G YQ C
Sbjct: 239 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGT--YQCSCNPGYQ 296
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECA 328
+ G + G S+GS + ++ G + D+DEC
Sbjct: 297 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGS-YECSCSEGYALMPDGRSCA---DIDECE 352
Query: 329 ENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
N C +C N G Y C C+ GF + C
Sbjct: 353 NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 387
Score = 43.6 bits (98), Expect = 0.002
Identities = 17/43 (39%), Positives = 24/43 (55%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +EC+ N C+NTLG Y+CAC SGF+ C +
Sbjct: 1717 VDENECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHD 1759
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 2/38 (5%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHPN 358
D+DEC+ + CQ +C N+ G Y C C +GF L PN
Sbjct: 914 DIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPN 951
Score = 42.3 bits (95), Expect = 0.005
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECASI-DHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ DEC+S C + C N +G ++C C+ GYEL DGK C
Sbjct: 1037 DIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 1078
Score = 41.5 bits (93), Expect = 0.009
Identities = 13/44 (29%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D++EC+ ++ C++ +C N +G Y+C+C+ G+ P++ C +
Sbjct: 263 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTD 306
Score = 41.5 bits (93), Expect = 0.009
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + +Q + H +GF A +DVDEC + G C NT+G Y C
Sbjct: 964 PNVCSHGLCVDLQGSYQCICH-NGFKASQDQTMCMDVDECERHPCG-NGTCKNTVGSYNC 1021
Query: 348 ACHSGFTLHPNKHDC 362
C+ GF L N +DC
Sbjct: 1022 LCYPGFELTHN-NDC 1035
Score = 41.1 bits (92), Expect = 0.012
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID++EC E+ C C NT GG++C C GF L N C
Sbjct: 1119 IDINECDEDPNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRC 1160
Score = 41.1 bits (92), Expect = 0.012
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + + C++ C+NT+G + C C +GY G C
Sbjct: 1512 RDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSC 1553
Score = 40.3 bits (90), Expect = 0.020
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGP--NGTIT 218
++ +EC CS+ C+NT G + C C +GY L G +C + ++ P NGT T
Sbjct: 1234 EDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGNGTCT 1293
Query: 219 S 219
+
Sbjct: 1294 N 1294
Score = 40.3 bits (90), Expect = 0.020
Identities = 14/31 (45%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DV+EC+ + C + C NT GGY C C G+
Sbjct: 1759 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 1789
Score = 39.5 bits (88), Expect = 0.036
Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 160 FMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
F K+ +EC + C++ C NT+G ++C C+ G+ L + + C
Sbjct: 134 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 177
Score = 39.5 bits (88), Expect = 0.036
Identities = 15/43 (34%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DECA + C + C+N G Y C C++G+ SD + C++
Sbjct: 513 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQD 555
Score = 39.1 bits (87), Expect = 0.047
Identities = 15/43 (34%), Positives = 27/43 (62%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D+DEC+ G C++ C N +G ++C C+ G+ L P+ +C
Sbjct: 1036 LDIDECSSFFGQVCRNGRCFNEIGSFKCLCNEGYELTPDGKNC 1078
Score = 39.1 bits (87), Expect = 0.047
Identities = 14/31 (45%), Positives = 20/31 (64%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGY 193
+ +EC+S + C++ C NT GGY C C GY
Sbjct: 1759 DVNECSSSKNPCNYGCSNTEGGYLCGCPPGY 1789
Score = 37.9 bits (84), Expect = 0.11
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGA 209
+EC++ + S SC NTLG Y+CAC G+ C N C +
Sbjct: 1720 NECSNPNACGSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSS 1766
Score = 37.5 bits (83), Expect = 0.14
Identities = 14/40 (35%), Positives = 25/40 (62%), Gaps = 2/40 (5%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDG 199
++ DEC++ D+ C + C+N+ G Y C C G++L +G
Sbjct: 913 EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNG 952
Score = 37.5 bits (83), Expect = 0.14
Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH CV+ G Y+C C G++ D C
Sbjct: 958 NECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMC 996
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 12/62 (19%)
Query: 322 IDVDECAENNGGCQHE-CHNTLGGYECACHSGFTLHPN-----------KHDCKEGGCKH 369
+D +EC E C H C + G Y+C CH+GF + +H C G CK+
Sbjct: 955 VDRNECLEIPNVCSHGLCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGNGTCKN 1014
Query: 370 DV 371
V
Sbjct: 1015 TV 1016
Score = 36.7 bits (81), Expect = 0.25
Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 153 KAGFSATFMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYEL 195
KA T + DEC H C + +C NT+G Y C C G+EL
Sbjct: 988 KASQDQTMCMDVDECER--HPCGNGTCKNTVGSYNCLCYPGFEL 1029
Score = 36.7 bits (81), Expect = 0.25
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 162 KEFDECASIDHGCSHS---CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
K+ DECA H C C N +G + C C G DG+ C EN C
Sbjct: 1357 KDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENEC 1406
Score = 36.7 bits (81), Expect = 0.25
Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC---KEGGCKHDV 371
+D +EC G C++ C N +G Y C C+ GF + +C ++G C +V
Sbjct: 1401 VDENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEV 1454
Score = 35.9 bits (79), Expect = 0.44
Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query: 323 DVDECAENNGGCQHE---CHNTLGGYECACHSGFTLHPNKHDC-KEGGCK 368
D+DECAE C+ C N +G + C C G P+ C E C+
Sbjct: 1358 DLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGCVDENECR 1407
Score = 35.5 bits (78), Expect = 0.58
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYELHS----DGKKCENACGGALYGPNGTITS 219
+EC ++ CS +C N G + C C GYE+ S D +C+ L+G + T T
Sbjct: 1082 NECVALPGSCSPGTCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFG-SCTNTP 1140
Query: 220 PSFPELYPP 228
F L PP
Sbjct: 1141 GGFQCLCPP 1149
Score = 34.3 bits (75), Expect = 1.3
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 322 IDVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHG 376
ID +EC C + C NT G + C C GF+L +C++ C + HG
Sbjct: 1634 IDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHG 1691
Score = 33.9 bits (74), Expect = 1.8
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+EC S C C NT G + C C G+ L + G CE+ C G
Sbjct: 1637 NECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDG 1684
Score = 31.9 bits (69), Expect = 7.2
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C N+ G + C C G TL C
Sbjct: 19 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 59
Score = 31.5 bits (68), Expect = 9.5
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 17/87 (19%)
Query: 323 DVDECAENNGGCQHE-CHNTLGGYECAC----HSGFTLHPNKHDCKEGGCKHDVTLPHGT 377
D+DEC + C C NT G +EC C SGF + N D E C+ + L G
Sbjct: 179 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE--CERNPLLCRGG 236
Query: 378 I-------FSPNYPAAY---PARKDCV 394
F + P + P+R+DCV
Sbjct: 237 TCVNTEGSFQCDCPLGHELSPSREDCV 263
>AL834404-1|CAD39066.1| 451|Homo sapiens hypothetical protein
protein.
Length = 451
Score = 67.7 bits (158), Expect = 1e-10
Identities = 48/177 (27%), Positives = 78/177 (44%), Gaps = 18/177 (10%)
Query: 401 PGHRIKLIFNV-FELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYM 459
P RI+L F+ + +EP EC +DH+ + DG + +CG K P L+ ++ M++
Sbjct: 6 PRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWI 65
Query: 460 VFKSDGSVQRKGFLATHS-------TACGGYLSATEEVKHLYSHA----RYGDNAYESR- 507
F SD ++ GF A +S T GG L+ + + S A R E +
Sbjct: 66 KFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKT 125
Query: 508 -----ADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
DC W I+A + L FL +++E C+ ++V V+ FC
Sbjct: 126 KPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFC 182
Score = 54.0 bits (124), Expect = 2e-06
Identities = 26/65 (40%), Positives = 37/65 (56%)
Query: 96 FEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAG 155
+ +E C +D ++VRDG SPLI +CG K PP IRST + + F SD ++ G
Sbjct: 18 YYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLG 77
Query: 156 FSATF 160
F A +
Sbjct: 78 FRAKY 82
Score = 49.6 bits (113), Expect = 3e-05
Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 2/82 (2%)
Query: 516 APRNHFVKLTFLT-FELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKMPPEIVSTSEAL 574
APR ++LTF + +E CR+D+++V +CG+K PP I ST +
Sbjct: 5 APRQR-IELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFM 63
Query: 575 LVRFRTDDSLVFKGFSASYQMV 596
++F +D+ L GF A Y +
Sbjct: 64 WIKFSSDEELEGLGFRAKYSFI 85
Score = 44.8 bits (101), Expect = 0.001
Identities = 20/75 (26%), Positives = 38/75 (50%)
Query: 392 DCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKLPHLVM 451
DC+W TP +I L F +++E EC + V +YDG+S+ FC + +++
Sbjct: 132 DCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVAVYDGSSSIENLKAKFCSTVANDVML 191
Query: 452 ASQNQMYMVFKSDGS 466
+ + ++ +GS
Sbjct: 192 KTGIGVIRMWADEGS 206
Score = 44.0 bits (99), Expect = 0.002
Identities = 46/199 (23%), Positives = 82/199 (41%), Gaps = 24/199 (12%)
Query: 4 APVLGRLCGSGKGPMMRSTGSRLTVVYQPGLRLKPHRGFRAFYEAV-------CGG---- 52
+P++ R CG P++RSTG + + + L+ GFRA Y + GG
Sbjct: 41 SPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEG-LGFRAKYSFIPDPDFTYLGGILNP 99
Query: 53 --DIEVDSNG-----HLESPNYPDDYQPNKL--CIWKLSVPQDYQVALRFHSFEVENHDT 103
D + + +G + +P + CIW + ++ LRF +++E+ +
Sbjct: 100 IPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNE 159
Query: 104 CSYDKVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKE 163
C + V V DG S L FC + D+ + ++ +D + + F F
Sbjct: 160 CKRNFVAVYDGSSSIENLKAKFCS-TVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSF 218
Query: 164 FD-ECASIDHGC-SHSCVN 180
+ C S C S+ C+N
Sbjct: 219 VEPPCTSSTFFCHSNMCIN 237
Score = 38.3 bits (85), Expect = 0.083
Identities = 27/85 (31%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 238 APPQHRITLNFT-HFDLEGNHMYQQECEYDSVTVHS-KLGADVLRRHGAFCGTALPPPVT 295
A P+ RI L F H+ +E + EC +D + V G L +CG PP +
Sbjct: 4 AAPRQRIELTFDEHYYIEPSF----ECRFDHLEVRDGPFGFSPLIDR--YCGVKSPPLIR 57
Query: 296 SDGSVLRVQFTSDGSVHRSGFAAVY 320
S G + ++F+SD + GF A Y
Sbjct: 58 STGRFMWIKFSSDEELEGLGFRAKY 82
Score = 35.1 bits (77), Expect = 0.77
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 13/153 (8%)
Query: 231 NCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTAL 290
+C+W I A P+ +I L F + +E + EC+ + V V+ + + FC T
Sbjct: 132 DCIWTIKATPKAKIYLRFLDYQME----HSNECKRNFVAVYDG-SSSIENLKAKFCSTVA 186
Query: 291 PPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVD-ECAENNGGC-QHECHNTLGGYECA 348
+ G + + +GS S F ++ V+ C + C + C N C
Sbjct: 187 NDVMLKTGIGVIRMWADEGS-RLSRFRMLFTSFVEPPCTSSTFFCHSNMCIN--NSLVCN 243
Query: 349 CHSGFTLHPNKHDCKE---GGCKHDVTLPHGTI 378
+++ CKE G +T HGTI
Sbjct: 244 GVQNCAYPWDENHCKEKKKAGVFEQITKTHGTI 276
>X62009-1|CAB56757.1| 754|Homo sapiens fibrillin 5 protein.
Length = 754
Score = 67.3 bits (157), Expect = 2e-10
Identities = 71/257 (27%), Positives = 100/257 (38%), Gaps = 26/257 (10%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NAC-GGALYGPNGTITS 219
+ DEC ++ GC C N+ G YEC+C GY L DG+ C + C G T
Sbjct: 490 DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSCADIDECENNPDICDGGQCT- 548
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECE--YDSVTVHSKLGAD 277
+ P Y L C +A + ++ DL N ECE S H +LG
Sbjct: 549 -NIPGEYRCL--CYDGFMASMDMKTCIDVNECDLNSNICMFGECENTKGSFICHCQLGYS 605
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQ-FTSDGSVH---RSGFA--AVYYIDVDECAENN 331
V ++ C + + + GS R G+ + ID DEC+
Sbjct: 606 V-KKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDRDECSNGT 664
Query: 332 GGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAY 387
C +C NT G Y CAC GFT + C + C ++ L +G N P AY
Sbjct: 665 HQCSINAQCVNTPGSYRCACSEGFT--GDGFTCSDVDECAENINLCENGQCL--NVPGAY 720
Query: 388 PARKDCVWQFSTTPGHR 404
R +C F+ R
Sbjct: 721 --RCECEMGFTPASDSR 735
Score = 46.8 bits (106), Expect = 2e-04
Identities = 17/46 (36%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 320 YYIDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+Y D++EC G C + +C NT+G ++C C+SGF L + +C +
Sbjct: 318 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 363
Score = 46.4 bits (105), Expect = 3e-04
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKEG 365
DVDECAEN C++ +C N G Y C C GFT + C+ G
Sbjct: 697 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQGG 740
Score = 42.3 bits (95), Expect = 0.005
Identities = 54/215 (25%), Positives = 74/215 (34%), Gaps = 21/215 (9%)
Query: 163 EFDECASIDHGC-SHSCVNTLGGYECACDIGYELH-------SDGKKCEN---AC-GGAL 210
+ DEC C S CVNT G +EC C GYE D CE C GG
Sbjct: 363 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDGCERNPLLCRGGTC 422
Query: 211 YGPNGTI--TSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSV 268
G+ P EL P ++C+ + N ++ G YQ C
Sbjct: 423 VNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGT--YQCSCNPGYQ 480
Query: 269 TVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECA 328
+ G + G S+GS + ++ G + D+DEC
Sbjct: 481 ATPDRQGCTDIDECMIMNGGCDTQCTNSEGS-YECSCSEGYALMPDGRSCA---DIDECE 536
Query: 329 ENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
N C +C N G Y C C+ GF + C
Sbjct: 537 NNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC 571
Score = 41.5 bits (93), Expect = 0.009
Identities = 13/44 (29%), Positives = 30/44 (68%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D++EC+ ++ C++ +C N +G Y+C+C+ G+ P++ C +
Sbjct: 447 VDINECSLSDNLCRNGKCVNMIGTYQCSCNPGYQATPDRQGCTD 490
Score = 40.3 bits (90), Expect = 0.020
Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGG 208
+ DECA + C + C+N G Y C C++G+ SD + C+ G
Sbjct: 697 DVDECAENINLCENGQCLNVPGAYRCECEMGFTPASDSRSCQGGSPG 743
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
ID+DEC N C + C NT G Y C C G+ C++
Sbjct: 57 IDIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED 100
Score = 39.5 bits (88), Expect = 0.036
Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 160 FMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
F K+ +EC + C++ C NT+G ++C C+ G+ L + + C
Sbjct: 318 FYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNC 361
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ C N G Y C C+ GYE + G+ C
Sbjct: 15 RDINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC 56
Score = 34.3 bits (75), Expect = 1.3
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 155 GFSATFMKEFDECASIDHGCSHS--------CVNTLGGYECACDIGYELHSDGKKC 202
G+ + FM C ID GC + CVNT G ++C C +G+EL + C
Sbjct: 393 GYESGFMM-MKNCMDID-GCERNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDC 446
Score = 33.9 bits (74), Expect = 1.8
Identities = 15/43 (34%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+ DEC C + C NT G Y C C GY ++ + CE+
Sbjct: 58 DIDECLVNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED 100
Score = 33.5 bits (73), Expect = 2.4
Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDC 362
D++ECA + C + C N G Y C C+SG+ + +C
Sbjct: 16 DINECALDPDICANGICENLRGSYRCNCNSGYEPDASGRNC 56
Score = 31.9 bits (69), Expect = 7.2
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 5/57 (8%)
Query: 160 FMKEFDECASIDHGCSHSCVN-----TLGGYECACDIGYELHSDGKKCENACGGALY 211
F E + C I+ S+ CVN LG + C C G +L S G C ++ G +
Sbjct: 91 FRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCW 147
Score = 31.9 bits (69), Expect = 7.2
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C N+ G + C C G TL C
Sbjct: 203 DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 243
Score = 31.9 bits (69), Expect = 7.2
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 17/87 (19%)
Query: 323 DVDECAENNGGCQHE-CHNTLGGYECAC----HSGFTLHPNKHDCKEGGCKHDVTLPHGT 377
D+DEC + C C NT G +EC C SGF + N D GC+ + L G
Sbjct: 363 DIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDI--DGCERNPLLCRGG 420
Query: 378 I-------FSPNYPAAY---PARKDCV 394
F + P + P+R+DCV
Sbjct: 421 TCVNTEGSFQCDCPLGHELSPSREDCV 447
>Z97832-1|CAI20187.1| 993|Homo sapiens protein ( Human DNA sequence
from clone RP3-329A5 on chromosome 6p21.1-21.33. ).
Length = 993
Score = 66.5 bits (155), Expect = 3e-10
Identities = 25/41 (60%), Positives = 28/41 (68%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDECAE NGGCQ C N +G YEC C GF L N+H C
Sbjct: 111 LDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 65.7 bits (153), Expect = 5e-10
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D+DEC NNGGC H C NT+G +EC+C G+ L N+ +C++ C D T H + +P
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTP 336
Score = 54.0 bits (124), Expect = 2e-06
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC +CH+ G C C GF L P++ CK+ GGC H
Sbjct: 237 IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Score = 52.8 bits (121), Expect = 4e-06
Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DVDEC E+N GC H+C N G Y C C+ GF L + H+C
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 52.4 bits (120), Expect = 5e-06
Identities = 23/43 (53%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSG-FTLHPNKHDCKE 364
DVDEC+ N GGC+ C NT G Y+C C +G LH N DC E
Sbjct: 357 DVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 52.0 bits (119), Expect = 6e-06
Identities = 31/129 (24%), Positives = 54/129 (41%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
CK C ++ G I SPNYP YPA +C+W + P +I ++ L EC
Sbjct: 799 CKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG 858
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
V + + + + T + P A ++++ FK+ + +GF + T
Sbjct: 859 DVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDE 918
Query: 482 GYLSATEEV 490
Y E++
Sbjct: 919 DYEQLVEDI 927
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G++ESPNYP +Y CIW ++ P ++ + + + D C D +
Sbjct: 804 CGGELG-EFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG-DVL 861
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P + S KL + F++ GF ++ +DE
Sbjct: 862 VMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYV-TYDE 918
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + GC H C NT+G +EC+C GY+L + + C++
Sbjct: 276 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDH-GCSHSCVNTLGGYECACDIGYELHSDGKKC 202
K+ DEC D+ GC H CVN G Y C C G+ L DG C
Sbjct: 69 KDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 46.8 bits (106), Expect = 2e-04
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C N GC H C T GG C C GF L N+ DCK GGC+H
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/40 (45%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DECA + GC SCVN +G YEC C G+ L + C
Sbjct: 112 DVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH F LH + C E
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIE 238
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGKKC 202
+ T + DEC+ GC C+NT G Y+C C G LH +GK C
Sbjct: 350 YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH-----SDGKKCENACGGALYG 212
++ DEC S D C H CVNT G ++C C GY L+ D +C GG +G
Sbjct: 317 QDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG 371
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC H+C +T G C C I + LH+DGK C C
Sbjct: 207 GCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETC 240
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 8/53 (15%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCK 368
D+DEC+ + C H C NT G ++C CH G+ L+ H +C GGC+
Sbjct: 318 DIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCR 369
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITL 246
+C+N CGG L G I SP++P YP C+W I PP+ +I +
Sbjct: 798 QCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILI 844
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 12/63 (19%)
Query: 323 DVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKH-----DCK---EGGCKHD-V 371
DVDEC E C + C NT Y+C C SG+T KH +C+ GC HD V
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT-GDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 TLP 374
+P
Sbjct: 88 NIP 90
Score = 40.7 bits (91), Expect = 0.015
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
C + +HGC+H C T GG C C G+EL + + C+ C YG G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN---YGNGG 207
Score = 36.3 bits (80), Expect = 0.33
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC C + G C C +G+ L D K C++
Sbjct: 238 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKD 277
Score = 31.9 bits (69), Expect = 7.2
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC C C NT Y+C C GY DGK C++
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKD 70
>BC052263-1|AAH52263.2| 992|Homo sapiens signal peptide, CUB
domain, EGF-like 3 protein.
Length = 992
Score = 66.5 bits (155), Expect = 3e-10
Identities = 25/41 (60%), Positives = 28/41 (68%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDECAE NGGCQ C N +G YEC C GF L N+H C
Sbjct: 111 LDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 65.7 bits (153), Expect = 5e-10
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D+DEC NNGGC H C NT+G +EC+C G+ L N+ +C++ C D T H + +P
Sbjct: 276 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTP 335
Score = 53.2 bits (122), Expect = 3e-06
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC +CH+ G C C GF L P++ CK+ GGC H
Sbjct: 236 IETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 289
Score = 52.8 bits (121), Expect = 4e-06
Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DVDEC E+N GC H+C N G Y C C+ GF L + H+C
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 52.4 bits (120), Expect = 5e-06
Identities = 23/43 (53%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSG-FTLHPNKHDCKE 364
DVDEC+ N GGC+ C NT G Y+C C +G LH N DC E
Sbjct: 356 DVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTE 398
Score = 52.0 bits (119), Expect = 6e-06
Identities = 31/129 (24%), Positives = 54/129 (41%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
CK C ++ G I SPNYP YPA +C+W + P +I ++ L EC
Sbjct: 798 CKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG 857
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
V + + + + T + P A ++++ FK+ + +GF + T
Sbjct: 858 DVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDE 917
Query: 482 GYLSATEEV 490
Y E++
Sbjct: 918 DYEQLVEDI 926
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G++ESPNYP +Y CIW ++ P ++ + + + D C D +
Sbjct: 803 CGGELG-EFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG-DVL 860
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P + S KL + F++ GF ++ +DE
Sbjct: 861 VMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYV-TYDE 917
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + GC H C NT+G +EC+C GY+L + + C++
Sbjct: 275 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 317
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDH-GCSHSCVNTLGGYECACDIGYELHSDGKKC 202
K+ DEC D+ GC H CVN G Y C C G+ L DG C
Sbjct: 69 KDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 46.8 bits (106), Expect = 2e-04
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C N GC H C T GG C C GF L N+ DCK GGC+H
Sbjct: 160 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH 209
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/40 (45%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DECA + GC SCVN +G YEC C G+ L + C
Sbjct: 112 DVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH F LH + C E
Sbjct: 200 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIE 237
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGKKC 202
+ T + DEC+ GC C+NT G Y+C C G LH +GK C
Sbjct: 349 YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDC 396
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH-----SDGKKCENACGGALYG 212
++ DEC S D C H CVNT G ++C C GY L+ D +C GG +G
Sbjct: 316 QDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG 370
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC H+C +T G C C I + LH+DGK C C
Sbjct: 206 GCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETC 239
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 8/53 (15%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCK 368
D+DEC+ + C H C NT G ++C CH G+ L+ H +C GGC+
Sbjct: 317 DIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCR 368
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITL 246
+C+N CGG L G I SP++P YP C+W I PP+ +I +
Sbjct: 797 QCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILI 843
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 12/63 (19%)
Query: 323 DVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKH-----DCK---EGGCKHD-V 371
DVDEC E C + C NT Y+C C SG+T KH +C+ GC HD V
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT-GDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 TLP 374
+P
Sbjct: 88 NIP 90
Score = 40.7 bits (91), Expect = 0.015
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
C + +HGC+H C T GG C C G+EL + + C+ C YG G
Sbjct: 160 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN---YGNGG 206
Score = 35.5 bits (78), Expect = 0.58
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC C + G C C +G+ L D K C++
Sbjct: 237 ETCAVNNGGCDSKCHDAAIGVHCTCPVGFMLQPDRKTCKD 276
Score = 31.9 bits (69), Expect = 7.2
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC C C NT Y+C C GY DGK C++
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKD 70
>AY639608-1|AAU08347.1| 993|Homo sapiens signal peptide, CUB and
EGF-like domain containing protein 3 protein.
Length = 993
Score = 66.5 bits (155), Expect = 3e-10
Identities = 25/41 (60%), Positives = 28/41 (68%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDECAE NGGCQ C N +G YEC C GF L N+H C
Sbjct: 111 LDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 65.7 bits (153), Expect = 5e-10
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D+DEC NNGGC H C NT+G +EC+C G+ L N+ +C++ C D T H + +P
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTP 336
Score = 54.0 bits (124), Expect = 2e-06
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC +CH+ G C C GF L P++ CK+ GGC H
Sbjct: 237 IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Score = 52.8 bits (121), Expect = 4e-06
Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DVDEC E+N GC H+C N G Y C C+ GF L + H+C
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 52.4 bits (120), Expect = 5e-06
Identities = 23/43 (53%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSG-FTLHPNKHDCKE 364
DVDEC+ N GGC+ C NT G Y+C C +G LH N DC E
Sbjct: 357 DVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 52.0 bits (119), Expect = 6e-06
Identities = 31/129 (24%), Positives = 54/129 (41%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
CK C ++ G I SPNYP YPA +C+W + P +I ++ L EC
Sbjct: 799 CKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG 858
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
V + + + + T + P A ++++ FK+ + +GF + T
Sbjct: 859 DVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDE 918
Query: 482 GYLSATEEV 490
Y E++
Sbjct: 919 DYEQLVEDI 927
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G++ESPNYP +Y CIW ++ P ++ + + + D C D +
Sbjct: 804 CGGELG-EFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG-DVL 861
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P + S KL + F++ GF ++ +DE
Sbjct: 862 VMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYV-TYDE 918
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + GC H C NT+G +EC+C GY+L + + C++
Sbjct: 276 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDH-GCSHSCVNTLGGYECACDIGYELHSDGKKC 202
K+ DEC D+ GC H CVN G Y C C G+ L DG C
Sbjct: 69 KDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 46.8 bits (106), Expect = 2e-04
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C N GC H C T GG C C GF L N+ DCK GGC+H
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/40 (45%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DECA + GC SCVN +G YEC C G+ L + C
Sbjct: 112 DVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH F LH + C E
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIE 238
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGKKC 202
+ T + DEC+ GC C+NT G Y+C C G LH +GK C
Sbjct: 350 YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH-----SDGKKCENACGGALYG 212
++ DEC S D C H CVNT G ++C C GY L+ D +C GG +G
Sbjct: 317 QDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG 371
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC H+C +T G C C I + LH+DGK C C
Sbjct: 207 GCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETC 240
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 8/53 (15%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCK 368
D+DEC+ + C H C NT G ++C CH G+ L+ H +C GGC+
Sbjct: 318 DIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCR 369
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITL 246
+C+N CGG L G I SP++P YP C+W I PP+ +I +
Sbjct: 798 QCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILI 844
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 12/63 (19%)
Query: 323 DVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKH-----DCK---EGGCKHD-V 371
DVDEC E C + C NT Y+C C SG+T KH +C+ GC HD V
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT-GDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 TLP 374
+P
Sbjct: 88 NIP 90
Score = 40.7 bits (91), Expect = 0.015
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
C + +HGC+H C T GG C C G+EL + + C+ C YG G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN---YGNGG 207
Score = 36.3 bits (80), Expect = 0.33
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC C + G C C +G+ L D K C++
Sbjct: 238 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKD 277
Score = 31.9 bits (69), Expect = 7.2
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC C C NT Y+C C GY DGK C++
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKD 70
>AF452494-1|AAN76808.1| 993|Homo sapiens CUB and EGF containing
protein protein.
Length = 993
Score = 66.5 bits (155), Expect = 3e-10
Identities = 25/41 (60%), Positives = 28/41 (68%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDECAE NGGCQ C N +G YEC C GF L N+H C
Sbjct: 111 LDVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 65.7 bits (153), Expect = 5e-10
Identities = 26/60 (43%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
D+DEC NNGGC H C NT+G +EC+C G+ L N+ +C++ C D T H + +P
Sbjct: 277 DIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQDIDECSFDRTCDHICVNTP 336
Score = 54.0 bits (124), Expect = 2e-06
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 8/54 (14%)
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKH 369
++ CA NNGGC +CH+ G C C GF L P++ CK+ GGC H
Sbjct: 237 IETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKDIDECRLNNGGCDH 290
Score = 52.8 bits (121), Expect = 4e-06
Identities = 21/41 (51%), Positives = 26/41 (63%), Gaps = 1/41 (2%)
Query: 323 DVDECA-ENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DVDEC E+N GC H+C N G Y C C+ GF L + H+C
Sbjct: 70 DVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 52.4 bits (120), Expect = 5e-06
Identities = 23/43 (53%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSG-FTLHPNKHDCKE 364
DVDEC+ N GGC+ C NT G Y+C C +G LH N DC E
Sbjct: 357 DVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDCTE 399
Score = 52.0 bits (119), Expect = 6e-06
Identities = 31/129 (24%), Positives = 54/129 (41%)
Query: 362 CKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECA 421
CK C ++ G I SPNYP YPA +C+W + P +I ++ L EC
Sbjct: 799 CKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG 858
Query: 422 YDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGFLATHSTACG 481
V + + + + T + P A ++++ FK+ + +GF + T
Sbjct: 859 DVLVMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYVTYDE 918
Query: 482 GYLSATEEV 490
Y E++
Sbjct: 919 DYEQLVEDI 927
Score = 50.4 bits (115), Expect = 2e-05
Identities = 31/118 (26%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG++ + G++ESPNYP +Y CIW ++ P ++ + + + D C D +
Sbjct: 804 CGGELG-EFTGYIESPNYPGNYPAGVECIWNINPPPKRKILIVVPEIFLPSEDECG-DVL 861
Query: 110 KVRDGDSMDSPLIGMFC-GHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
+R S S C ++ P + S KL + F++ GF ++ +DE
Sbjct: 862 VMRKNSSPSSITTYETCQTYERPIAFTARSRKLWINFKTSEANSARGFQIPYV-TYDE 918
Score = 50.0 bits (114), Expect = 3e-05
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
K+ DEC + GC H C NT+G +EC+C GY+L + + C++
Sbjct: 276 KDIDECRLNNGGCDHICRNTVGSFECSCKKGYKLLINERNCQD 318
Score = 47.6 bits (108), Expect = 1e-04
Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDH-GCSHSCVNTLGGYECACDIGYELHSDGKKC 202
K+ DEC D+ GC H CVN G Y C C G+ L DG C
Sbjct: 69 KDVDECEREDNAGCVHDCVNIPGNYRCTCYDGFHLAHDGHNC 110
Score = 46.8 bits (106), Expect = 2e-04
Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 7/50 (14%)
Query: 327 CAENNGGCQHECHNT-LGGYECACHSGFTLHPNKHDCK------EGGCKH 369
C N GC H C T GG C C GF L N+ DCK GGC+H
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCNYGNGGCQH 210
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/40 (45%), Positives = 23/40 (57%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DECA + GC SCVN +G YEC C G+ L + C
Sbjct: 112 DVDECAEGNGGCQQSCVNMMGSYECHCREGFFLSDNQHTC 151
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
C NGGCQH C +T G C CH F LH + C E
Sbjct: 201 CNYGNGGCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIE 238
Score = 45.6 bits (103), Expect = 5e-04
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 156 FSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGY-ELHSDGKKC 202
+ T + DEC+ GC C+NT G Y+C C G LH +GK C
Sbjct: 350 YGITHCGDVDECSINRGGCRFGCINTPGSYQCTCPAGQGRLHWNGKDC 397
Score = 44.4 bits (100), Expect = 0.001
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELH-----SDGKKCENACGGALYG 212
++ DEC S D C H CVNT G ++C C GY L+ D +C GG +G
Sbjct: 317 QDIDEC-SFDRTCDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCRFG 371
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 20/34 (58%)
Query: 173 GCSHSCVNTLGGYECACDIGYELHSDGKKCENAC 206
GC H+C +T G C C I + LH+DGK C C
Sbjct: 207 GCQHTCDDTEQGPRCGCHIKFVLHTDGKTCIETC 240
Score = 42.7 bits (96), Expect = 0.004
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 8/53 (15%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKH-----DC--KEGGCK 368
D+DEC+ + C H C NT G ++C CH G+ L+ H +C GGC+
Sbjct: 318 DIDECSFDRT-CDHICVNTPGSFQCLCHRGYLLYGITHCGDVDECSINRGGCR 369
Score = 42.3 bits (95), Expect = 0.005
Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 201 KCENA-CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITL 246
+C+N CGG L G I SP++P YP C+W I PP+ +I +
Sbjct: 798 QCKNRQCGGELGEFTGYIESPNYPGNYPAGVECIWNINPPPKRKILI 844
Score = 41.1 bits (92), Expect = 0.012
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 12/63 (19%)
Query: 323 DVDECAENNGGCQHE--CHNTLGGYECACHSGFTLHPNKH-----DCK---EGGCKHD-V 371
DVDEC E C + C NT Y+C C SG+T KH +C+ GC HD V
Sbjct: 29 DVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT-GDGKHCKDVDECEREDNAGCVHDCV 87
Query: 372 TLP 374
+P
Sbjct: 88 NIP 90
Score = 40.7 bits (91), Expect = 0.015
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 4/50 (8%)
Query: 167 CASIDHGCSHSCVNT-LGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
C + +HGC+H C T GG C C G+EL + + C+ C YG G
Sbjct: 161 CMNKNHGCAHICRETPKGGIACECRPGFELTKNQRDCKLTCN---YGNGG 207
Score = 36.3 bits (80), Expect = 0.33
Identities = 13/40 (32%), Positives = 20/40 (50%)
Query: 165 DECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ CA + GC C + G C C +G+ L D K C++
Sbjct: 238 ETCAVNNGGCDSKCHDAATGVHCTCPVGFMLQPDRKTCKD 277
Score = 31.9 bits (69), Expect = 7.2
Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC C C NT Y+C C GY DGK C++
Sbjct: 28 QDVDECVEGTDNCHIDAICQNTPRSYKCICKSGYT--GDGKHCKD 70
>AK223620-1|BAD97340.1| 994|Homo sapiens seizure related 6 homolog
protein.
Length = 994
Score = 65.7 bits (153), Expect = 5e-10
Identities = 55/225 (24%), Positives = 95/225 (42%), Gaps = 29/225 (12%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I + G + SP +P +Y N C W L P+ ++ L F + D D
Sbjct: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
Query: 108 KVKVRDGDSMDS-PLIGMFCGHKIPPD-IRSTSNKLLVIFESDSTVQKAGFSATFMK-EF 164
++ +R+GD++++ P+ + +P + + S+ V +DS+ AG + + +
Sbjct: 470 RLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
Query: 165 DECAS--IDHGCSHSCVNT--LG-GYECACDIGYELHSDG-----------------KKC 202
C + +G S T +G E +CD GY L C
Sbjct: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
C G + G + SP++PE Y ++C+W + RI L+
Sbjct: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD 634
Score = 63.7 bits (148), Expect = 2e-09
Identities = 70/295 (23%), Positives = 107/295 (36%), Gaps = 37/295 (12%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C ACGG + G I SP FP Y C W + AP R+ L+F L +
Sbjct: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD--- 468
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
D + + + + + ++ LP + S G V+ ++D S +G A
Sbjct: 469 -----DRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALR 523
Query: 320 YY-IDVDECAE-----NNGGCQHECHNTLGGYECACHSGFTLHPNK--------HDCK-- 363
Y C E N + E +C G+TL HD +
Sbjct: 524 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWN 583
Query: 364 ------EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
C ++T G + SPN+P Y +DC+W RI L V + P
Sbjct: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
D +T YDG + LG + G + + S + + F+SD G+
Sbjct: 644 -----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGY 693
Score = 54.8 bits (126), Expect = 9e-07
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
AVC G+I DS G + SPN+P+ Y + CIW + V +D ++ L + D ++
Sbjct: 591 AVCSGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF- 648
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DGD + + ++G + G + + ++ + + F+SD G+ F+ F E
Sbjct: 649 ----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 703
>AK091522-1|BAC03684.1| 869|Homo sapiens protein ( Homo sapiens
cDNA FLJ34203 fis, clone FCBBF3019784, highly similar to
Mouse mRNA for seizure-related gene product 6 type 2
precursor. ).
Length = 869
Score = 65.7 bits (153), Expect = 5e-10
Identities = 55/225 (24%), Positives = 95/225 (42%), Gaps = 29/225 (12%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
A CGG I + G + SP +P +Y N C W L P+ ++ L F + D D
Sbjct: 289 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 344
Query: 108 KVKVRDGDSMDS-PLIGMFCGHKIPPD-IRSTSNKLLVIFESDSTVQKAGFSATFMK-EF 164
++ +R+GD++++ P+ + +P + + S+ V +DS+ AG + + +
Sbjct: 345 RLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 404
Query: 165 DECAS--IDHGCSHSCVNT--LG-GYECACDIGYELHSDG-----------------KKC 202
C + +G S T +G E +CD GY L C
Sbjct: 405 GHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 464
Query: 203 ENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
C G + G + SP++PE Y ++C+W + RI L+
Sbjct: 465 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD 509
Score = 63.7 bits (148), Expect = 2e-09
Identities = 70/295 (23%), Positives = 107/295 (36%), Gaps = 37/295 (12%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C ACGG + G I SP FP Y C W + AP R+ L+F L +
Sbjct: 287 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD--- 343
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
D + + + + + ++ LP + S G V+ ++D S +G A
Sbjct: 344 -----DRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALR 398
Query: 320 YY-IDVDECAE-----NNGGCQHECHNTLGGYECACHSGFTLHPNK--------HDCK-- 363
Y C E N + E +C G+TL HD +
Sbjct: 399 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWN 458
Query: 364 ------EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
C ++T G + SPN+P Y +DC+W RI L V + P
Sbjct: 459 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 518
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
D +T YDG + LG + G + + S + + F+SD G+
Sbjct: 519 -----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGY 568
Score = 54.8 bits (126), Expect = 9e-07
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
AVC G+I DS G + SPN+P+ Y + CIW + V +D ++ L + D ++
Sbjct: 466 AVCSGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF- 523
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DGD + + ++G + G + + ++ + + F+SD G+ F+ F E
Sbjct: 524 ----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 578
>AB011541-1|BAA32469.2| 2785|Homo sapiens MEGF8 protein.
Length = 2785
Score = 65.7 bits (153), Expect = 5e-10
Identities = 54/167 (32%), Positives = 74/167 (44%), Gaps = 21/167 (12%)
Query: 63 ESPNYPDD----YQPNKLCIWKLSVPQ-DYQVALRFHSFEVENHDTCSYDKVKVRDGDSM 117
E+P + D Y N C W + P +++ L F + E C+YD + V DGDS
Sbjct: 46 EAPGFVTDGAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSP 101
Query: 118 DSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDECASIDHGC-SH 176
PL+ G PP I ++S K+L+ SD+ GF+A+F F C GC SH
Sbjct: 102 RGPLLASLSGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASF--RFSLCPG---GCQSH 156
Query: 177 SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
G CAC+ G+ G C A G +GT SP P
Sbjct: 157 GQCQPPG--VCACEPGW----GGPDCGLQECSAYCGSHGTCASPLGP 197
Score = 49.2 bits (112), Expect = 4e-05
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Query: 500 GDNAYESRADCDWNIEAPR-NHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTF 558
G Y +C+W IEAP H + L FL + E C YDY+ V+ +
Sbjct: 54 GAGNYSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASL 109
Query: 559 CGIKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQ 594
G PP I ++S +L+ +D + GF+AS++
Sbjct: 110 SGSTRPPPIEASSGKMLLHLFSDANYNLLGFNASFR 145
Score = 46.8 bits (106), Expect = 2e-04
Identities = 49/157 (31%), Positives = 63/157 (40%), Gaps = 25/157 (15%)
Query: 231 NCLWEIVAP-PQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRH--GAFCG 287
NC W I AP PQHRI L+F D EC YD + V+ D R + G
Sbjct: 63 NCEWLIEAPSPQHRILLDFLFLD--------TECTYDYLFVYD---GDSPRGPLLASLSG 111
Query: 288 TALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHNTLGGYEC 347
+ PPP+ + + + SD + + GF A + + C GGCQ G C
Sbjct: 112 STRPPPIEASSGKMLLHLFSDANYNLLGFNASFRFSL--CP---GGCQSHGQCQPPGV-C 165
Query: 348 ACHSGFTLHPNKHDCKEGGCKHDVTLPHGTIFSPNYP 384
AC G+ DC C HGT SP P
Sbjct: 166 ACEPGW----GGPDCGLQECS-AYCGSHGTCASPLGP 197
Score = 45.2 bits (102), Expect = 7e-04
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 387 YPARKDCVWQFST-TPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSK 445
Y +C W +P HRI L F + E C YD++ +YDG S L GS
Sbjct: 58 YSVNGNCEWLIEAPSPQHRILLDFLFLDTE----CTYDYLFVYDGDSPRGPLLASLSGST 113
Query: 446 LPHLVMASQNQMYMVFKSDGSVQRKGFLAT 475
P + AS +M + SD + GF A+
Sbjct: 114 RPPPIEASSGKMLLHLFSDANYNLLGFNAS 143
Score = 37.9 bits (84), Expect = 0.11
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 4/58 (6%)
Query: 165 DECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSP 220
DECA+ H C+ + C + GYEC+C GY + + C C NG+ P
Sbjct: 2120 DECANGHHDCNETQNCHDQPHGYECSCKTGYTMDNMTGLCRPVCAQGCV--NGSCVEP 2175
Score = 37.5 bits (83), Expect = 0.14
Identities = 14/33 (42%), Positives = 20/33 (60%), Gaps = 2/33 (6%)
Query: 325 DECAENNGGCQH--ECHNTLGGYECACHSGFTL 355
DECA + C CH+ GYEC+C +G+T+
Sbjct: 2120 DECANGHHDCNETQNCHDQPHGYECSCKTGYTM 2152
>AY165865-1|AAO18147.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 3 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AY165864-1|AAO18146.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 2 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AY165863-1|AAO18145.1| 2809|Homo sapiens fibrillin-3 short form
precursor transcript variant 1 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AL731551-2|CAI40247.1| 88|Homo sapiens cubilin (intrinsic
factor-cobalamin receptor) protein.
Length = 88
Score = 65.3 bits (152), Expect = 6e-10
Identities = 33/87 (37%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Query: 21 STGSRLTVVYQPGLRLKPHRGFRAFYEAV---CGGDIEVDSNGHLESPNYPDDYQPNKLC 77
STG+ L + ++ L + RGF A ++AV CGG + S G + SPNYP Y+ N C
Sbjct: 1 STGNELAIRFKTDLSING-RGFNASWQAVTGGCGGIFQAPS-GEIHSPNYPSPYRSNTDC 58
Query: 78 IWKLSVPQDYQVALRFHSFEVENHDTC 104
W + V ++++V L F F++E D+C
Sbjct: 59 SWVIRVDRNHRVLLNFTDFDLEPQDSC 85
Score = 56.4 bits (130), Expect = 3e-07
Identities = 24/56 (42%), Positives = 28/56 (50%)
Query: 365 GGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
GGC P G I SPNYP+ Y + DC W HR+ L F F+LEP C
Sbjct: 30 GGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLEPQDSC 85
Score = 54.0 bits (124), Expect = 2e-06
Identities = 23/49 (46%), Positives = 28/49 (57%)
Query: 206 CGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE 254
CGG P+G I SP++P Y +C W I HR+ LNFT FDLE
Sbjct: 32 CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLE 80
Score = 50.8 bits (116), Expect = 1e-05
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 455 NQMYMVFKSDGSVQRKGFLATHSTA---CGGYLSATEEVKHLYSHARYGDNAYESRADCD 511
N++ + FK+D S+ +GF A+ CGG A H ++ + Y S DC
Sbjct: 4 NELAIRFKTDLSINGRGFNASWQAVTGGCGGIFQAPSGEIHSPNYP----SPYRSNTDCS 59
Query: 512 WNIEAPRNHFVKLTFLTFELEREANC 537
W I RNH V L F F+LE + +C
Sbjct: 60 WVIRVDRNHRVLLNFTDFDLEPQDSC 85
>AB177800-1|BAD16736.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCWGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AB177799-1|BAD16735.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AB177798-1|BAD16734.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AB177797-1|BAD16733.1| 2809|Homo sapiens fibrillin 3 protein.
Length = 2809
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 983 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1042
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1043 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1102
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1103 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1153
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1154 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1211
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1212 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1247
Score = 58.8 bits (136), Expect = 5e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1155 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1211
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1270
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1271 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEH 1330
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1331 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1385
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1386 -RCECEMGFDPTEDHR 1400
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1403 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1462
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1463 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1514
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1515 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1573
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1574 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGTCYNTLGNYTCVCP 1633
Query: 389 A 389
A
Sbjct: 1634 A 1634
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 626
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 627 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 674
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 675 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 732
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 733 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2485 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1969 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2027
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2028 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2082
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2083 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2141 CTNVIGGFECACADGF 2156
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCE---------NACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE + CG G
Sbjct: 1561 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSSICGPGT 1620
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1621 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1668
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1669 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1724
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1725 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1784
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1785 GSY--RCKCTRGYKLSPG 1800
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2528 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2566
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2399 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2527 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2572
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 477 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 535
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 536 ATSTMCVNG 544
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2166 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2445 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2497
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 488 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 529
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2610 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2640
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2446 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2479
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2254 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2313
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2314 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2371
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2372 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2422
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2423 TKGSFLCSCPRGYLLEEDGRTCKD 2446
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 246 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 296
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1968 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2009
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1350 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2165 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1109 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1153
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2362 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2403
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1359 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1404
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2609 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2661
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 448 IDVDECTSSP--CHHGDCVNIPGTYHCQCYPGFQATPTRQAC 487
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2128 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2157
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1404 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1461
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1462 NTPGSYLC--SCPQDFELNP 1479
Score = 39.1 bits (87), Expect = 0.047
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1763 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSH 1818
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2567 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2610
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2084 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2117
Score = 37.1 bits (82), Expect = 0.19
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C N C
Sbjct: 1762 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGRNEC 1809
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1845
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2083 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2124
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2534
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2570 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2616
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 530 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 572
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 714 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1807 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1813 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1870
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1871 LCFPGFVVTHN-GDC 1884
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 247 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1885 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1927
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2207 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2253
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1275 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1321
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2252 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2304
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 869 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 909
>AB053450-1|BAB47408.2| 2816|Homo sapiens fibrillin3 protein.
Length = 2816
Score = 65.3 bits (152), Expect = 6e-10
Identities = 69/278 (24%), Positives = 112/278 (40%), Gaps = 33/278 (11%)
Query: 160 FMKEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENA---------CG-G 208
F K+ +EC C+H +C NT+G + CAC G+ L + + C + CG G
Sbjct: 990 FYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG 1049
Query: 209 ALYGPNGTITSPSFPEL---YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEY 265
G+ FP + +KNC+ + T + +G++ Q +
Sbjct: 1050 TCVNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPPGH 1109
Query: 266 DSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVY----Y 321
+ +T D+ C +L + G + V S H +GF +
Sbjct: 1110 E-LTAKGTACEDIDE-----C--SLSDGLCPHGQCVNVIGAFQCSCH-AGFQSTPDRQGC 1160
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIF 379
+D++EC NGGC C NT G Y C+C G++L P+ C + C+ + + G
Sbjct: 1161 VDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQG--H 1218
Query: 380 SPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
N P + R C F TP R + + +L PH
Sbjct: 1219 CTNMPGGH--RCLCYDGFMATPDMRTCVDVDECDLNPH 1254
Score = 58.4 bits (135), Expect = 7e-08
Identities = 65/256 (25%), Positives = 94/256 (36%), Gaps = 24/256 (9%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSF 222
+ +EC + GC C+NT G Y C+C GY L DG+ C + N +
Sbjct: 1162 DINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECE---ENPRVCDQGH 1218
Query: 223 PELYPPLKNCLWE--IVAPPQHRITLNFTHFDLEGNHMYQQECEYD--SVTVHSKLGADV 278
P CL +A P R ++ DL + +CE S H +LG +
Sbjct: 1219 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGY-M 1277
Query: 279 LRRHGAFCGTALPPPV-----TSDGSVLRVQFTSDGSVHRSGFAAVYYI-DVDECAENNG 332
+R+ C V S S L + + + D+DEC
Sbjct: 1278 VRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECISQEH 1337
Query: 333 GC--QHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTL-PHGTIFSPNYPAAYP 388
C + +C N G Y C C GF + C++ C +V L +G N P Y
Sbjct: 1338 RCSPRGDCLNVPGSYRCTCRQGFA--GDGFFCEDRDECAENVDLCDNGQCL--NAPGGY- 1392
Query: 389 ARKDCVWQFSTTPGHR 404
R +C F T HR
Sbjct: 1393 -RCECEMGFDPTEDHR 1407
Score = 54.8 bits (126), Expect = 9e-07
Identities = 63/241 (26%), Positives = 94/241 (39%), Gaps = 22/241 (9%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCE--NACGGALYGPNGTITS 219
++ DECA + SC N G + C C+ GYEL G C N C + NG +
Sbjct: 1410 QDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCIN 1469
Query: 220 PSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS-VTVHSKLGADV 278
P Y L +C + P ++ GN + DS ++ +++G V
Sbjct: 1470 T--PGSY--LCSCPQDFELNPSGVGCVDTR----AGNCFLETHDRGDSGISCSAEIGVGV 1521
Query: 279 LRRHGAFC--GTALPPPVTSDGSVLRVQFTS---DGSVHRSGFAAVYYIDVDECAENNGG 333
R C G A P ++ + G + V D+DEC E G
Sbjct: 1522 TRA-SCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGL 1580
Query: 334 CQH-ECHNTLGGYECACHSGFTLHPNKHDCKE-GGCK-HDVTLPHGTIFSP--NYPAAYP 388
CQ +C NT G ++C C G+ L + C++ C H GT ++ NY P
Sbjct: 1581 CQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGTCYNTLGNYTCVCP 1640
Query: 389 A 389
A
Sbjct: 1641 A 1641
Score = 52.8 bits (121), Expect = 4e-06
Identities = 57/214 (26%), Positives = 86/214 (40%), Gaps = 25/214 (11%)
Query: 160 FMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC-----ENACGGALYGPN 214
+ + DEC + + C NT G + C C G + +DG+ C + C GA+
Sbjct: 576 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAI--EK 633
Query: 215 GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKL 274
G+ P FP + C A P H + + +Q C S L
Sbjct: 634 GSCARP-FPGTVTKSECCC----ANPDHGFGEPCQLCPAKNSAEFQALCS-------SGL 681
Query: 275 GADVLRRHGAFCGTALPPPVTSDGSV--LRVQFTSDGSV-HRSGFAAVYYIDVDECAENN 331
G R C AL P V ++G LR + ++ + +G + DVDECA N+
Sbjct: 682 GITTDGRDINEC--ALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNS 739
Query: 332 GGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE 364
C + C N+ G Y C+C GF + CK+
Sbjct: 740 LLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 773
Score = 49.6 bits (113), Expect = 3e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 323 DVDECAENNGGC--QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D DEC+ G C CHNT G + C CH GFTL + H C++
Sbjct: 2492 DNDECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2535
Score = 49.2 bits (112), Expect = 4e-05
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 13/196 (6%)
Query: 163 EFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPS 221
+ DEC+ + C +C N+ G ++C C G+ L +G +C + + S
Sbjct: 1976 DIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCF-TRFEAGKCS 2034
Query: 222 FPELYPPLKN-CLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLR 280
P+ + K C P EG+ +Q+ C + V G D R
Sbjct: 2035 VPKAFNTTKTRCCCS--KRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVP---GPDDSR 2089
Query: 281 RHGAFCGTALPPPVTSDGSVLRVQ--FTSDGSVHRS-GFAAVYYIDVDECAENNGGCQHE 337
C A P V ++G + F + S F + +D DEC+ + Q
Sbjct: 2090 EDVNEC--AENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2147
Query: 338 CHNTLGGYECACHSGF 353
C N +GG+ECAC GF
Sbjct: 2148 CTNVIGGFECACADGF 2163
Score = 48.8 bits (111), Expect = 6e-05
Identities = 60/258 (23%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 161 MKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN---------ACG-GA 209
+++ DEC + C CVNT G ++C C GY L + CE+ CG G
Sbjct: 1568 LEDIDECQELPGLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGICGPGT 1627
Query: 210 LYGPNGTITSPSFPELYPPL---KNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYD 266
Y G T P Y + NC+ R ++ F H+ N Q E ++
Sbjct: 1628 CYNTLGNYTCVC-PAEYLQVNGGNNCM-------DMRKSVCFRHY----NGTCQNELAFN 1675
Query: 267 SVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDE 326
++ + C A P P++ D +L + + +D+DE
Sbjct: 1676 VTRKMCCCSYNIGQAWNRPC-EACPTPISPDYQIL---CGNQAPGFLTDIHTGKPLDIDE 1731
Query: 327 CAENNGGCQHE-CHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSPNYP 384
C E C + C N +G + C C +GF + C++ C + N P
Sbjct: 1732 CGEIPAICANGICINQIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIP 1791
Query: 385 AAYPARKDCVWQFSTTPG 402
+Y R C + +PG
Sbjct: 1792 GSY--RCKCTRGYKLSPG 1807
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 2535 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 2573
Score = 48.0 bits (109), Expect = 1e-04
Identities = 18/48 (37%), Positives = 28/48 (58%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C++
Sbjct: 2406 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKD 2453
Score = 47.2 bits (107), Expect = 2e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ +EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 2534 EDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 2579
Score = 46.8 bits (106), Expect = 2e-04
Identities = 27/69 (39%), Positives = 35/69 (50%), Gaps = 9/69 (13%)
Query: 155 GFSATFMKE----FDECASIDHGCSH--SCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF AT ++ DEC + G H CVNT G ++C C+ G+EL DGK C N C
Sbjct: 484 GFQATPTRQACVDVDECI-VSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNCVDHNEC 542
Query: 207 GGALYGPNG 215
+ NG
Sbjct: 543 ATSTMCVNG 551
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 2173 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2214
Score = 46.4 bits (105), Expect = 3e-04
Identities = 21/54 (38%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNG 215
K+ DEC S H C CVNT+G + C C G+ H + C A GP G
Sbjct: 2452 KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDEC-SAQPGPCG 2504
Score = 45.6 bits (103), Expect = 5e-04
Identities = 18/42 (42%), Positives = 26/42 (61%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQ-HECHNTLGGYECACHSGFTLHPNKHDC 362
+DVDEC + G C C NT G ++C C++GF L P+ +C
Sbjct: 495 VDVDECIVSGGLCHLGRCVNTEGSFQCVCNAGFELSPDGKNC 536
Score = 44.0 bits (99), Expect = 0.002
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 163 EFDECAS-IDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+FDEC + + C C+NT G + C C G+EL +DGK C
Sbjct: 1893 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1934
Score = 44.0 bits (99), Expect = 0.002
Identities = 16/31 (51%), Positives = 19/31 (61%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGF 353
DVDECA G C + C NT GG+ C C G+
Sbjct: 2617 DVDECAGRRGPCSYSCANTPGGFLCGCPQGY 2647
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 2453 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 2486
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 2261 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 2320
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 2321 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 2378
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 2379 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 2429
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 2430 TKGSFLCSCPRGYLLEEDGRTCKD 2453
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 162 KEFDECASIDHGCSH-SCVNTLGGYECACDIGYELHSDGKKCENACGGALY 211
++ DEC ++ C SCVN +G + C C +G+ L CE+ GA +
Sbjct: 253 QDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYRAGACF 303
Score = 42.7 bits (96), Expect = 0.004
Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
ID+DEC+E C C N+ G ++C C GF L N H C
Sbjct: 1975 IDIDECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDNGHRC 2016
Score = 42.3 bits (95), Expect = 0.005
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 313 RSGFAAVYYI--DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
R GFA + D DECAEN C + +C N GGY C C GF + C++
Sbjct: 1357 RQGFAGDGFFCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1411
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 2172 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2214
Score = 41.9 bits (94), Expect = 0.007
Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 1/45 (2%)
Query: 159 TFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
T ++ DEC+ D C H CVN +G ++C+C G++ D + C
Sbjct: 1116 TACEDIDECSLSDGLCPHGQCVNVIGAFQCSCHAGFQSTPDRQGC 1160
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 2369 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 2410
Score = 41.5 bits (93), Expect = 0.009
Identities = 16/46 (34%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 160 FMKEFDECA-SIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
F ++ DECA ++D + C+N GGY C C++G++ D + C++
Sbjct: 1366 FCEDRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQD 1411
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 2616 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 2668
Score = 39.9 bits (89), Expect = 0.027
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 322 IDVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
IDVDEC + C H +C N G Y C C+ GF P + C
Sbjct: 455 IDVDECTSSP--CHHGDCVNIPGTYHCRCYPGFQATPTRQAC 494
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 2135 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 2164
Score = 39.1 bits (87), Expect = 0.047
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE-GGCKHDVTLPHGTIFSP 381
DVDECA+ N C N G + C C+ G+ L +C + C V +G
Sbjct: 1411 DVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCI-- 1468
Query: 382 NYPAAYPARKDCVWQFSTTP 401
N P +Y C F P
Sbjct: 1469 NTPGSYLC--SCPQDFELNP 1486
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 2574 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 2617
Score = 38.7 bits (86), Expect = 0.063
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 9/56 (16%)
Query: 323 DVDECAENNGGCQH--ECHNTLGGYECACHSGFTLHP-----NKHDCKE--GGCKH 369
DVDEC CQ +C N G Y C C G+ L P +++C+E C H
Sbjct: 1770 DVDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVGQNECREIPNVCSH 1825
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 2091 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 2124
Score = 37.9 bits (84), Expect = 0.11
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 5/49 (10%)
Query: 162 KEFDECASIDHGCSHS--CVNTLGGYECACDIGYELHSDGKKC--ENAC 206
++ DEC S + C + C+N G Y C C GY+L S G C +N C
Sbjct: 1769 EDVDECGSRESPCQQNADCINIPGSYRCKCTRGYKL-SPGGACVGQNEC 1816
Score = 37.1 bits (82), Expect = 0.19
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+EC I + CSH C++T G Y C C G++ +D C
Sbjct: 1814 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLC 1852
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 2090 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 2131
Score = 37.1 bits (82), Expect = 0.19
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 4/48 (8%)
Query: 165 DECASIDHGC-SHS-CVNTLGGYECACDIGYELHSDGKKCE--NACGG 208
DEC++ C +H C NT G + C C G+ L S G CE N C G
Sbjct: 2494 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDG 2541
Score = 35.9 bits (79), Expect = 0.44
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 165 DECASIDHGC-SHSCVNTLGGYECACDIGYELHSDGKKCENA--CGG 208
+ECA C S SC NTLGG+ C C G++ C++ C G
Sbjct: 2577 NECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQDVDECAG 2623
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/43 (34%), Positives = 20/43 (46%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C N G + C C GF L P H C +
Sbjct: 537 VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMD 579
Score = 35.5 bits (78), Expect = 0.58
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 153 KAGFSATFMKEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCEN 204
+AG S + DECA C + C N+ G Y C+C G+ D + C++
Sbjct: 721 EAGASGKDCTDVDECALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 773
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 163 EFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
+ +EC S C + CVNT G + C C G L + G+ C
Sbjct: 876 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 916
Score = 35.5 bits (78), Expect = 0.58
Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 325 DECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
+EC E C H +C +T G Y C CH GF ++ C +
Sbjct: 1814 NECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1854
Score = 35.1 bits (77), Expect = 0.77
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 292 PPVTSDGSVLRVQFTSDGSVHRSGFAA----VYYIDVDECAENNGGCQHECHNTLGGYEC 347
P V S G + + + HR GF A +D+DEC G C N +G Y C
Sbjct: 1820 PNVCSHGDCMDTEGSYMCLCHR-GFQASADQTLCMDIDECDRQPCG-NGTCKNIIGSYNC 1877
Query: 348 ACHSGFTLHPNKHDC 362
C GF + N DC
Sbjct: 1878 LCFPGFVVTHN-GDC 1891
Score = 34.3 bits (75), Expect = 1.3
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDCKE 364
DVDEC G CQ C N +G + C C G L + C++
Sbjct: 254 DVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 296
Score = 33.9 bits (74), Expect = 1.8
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 322 IDVDECAENNGG-CQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
+D DEC G C+ C NT G + C C GF L + +C
Sbjct: 1892 VDFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNC 1934
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 2214 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 2260
Score = 33.5 bits (73), Expect = 2.4
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 158 ATFMKEFDECASIDHGC-SH-SCVNTLGGYECACDIGYELHSDGKKCEN 204
AT + DEC H C SH SC+N G + C C G+ DG +C +
Sbjct: 1282 ATGCSDVDECEVGGHNCDSHASCLNIPGSFSCRCLPGWV--GDGFECHD 1328
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 2259 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 2311
Score = 32.7 bits (71), Expect = 4.1
Identities = 15/41 (36%), Positives = 19/41 (46%), Gaps = 1/41 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC G C + C NT G + C C G L + C
Sbjct: 876 DVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLC 916
>BC101705-1|AAI01706.1| 1272|Homo sapiens attractin protein.
Length = 1272
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL353193-3|CAH70472.1| 1429|Homo sapiens attractin protein.
Length = 1429
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL353193-2|CAH70471.1| 1272|Homo sapiens attractin protein.
Length = 1272
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL132773-2|CAI22616.1| 1429|Homo sapiens attractin protein.
Length = 1429
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL132773-1|CAI22614.1| 1272|Homo sapiens attractin protein.
Length = 1272
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL109805-3|CAI21878.1| 1429|Homo sapiens attractin protein.
Length = 1429
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AL109805-2|CAI21876.1| 1272|Homo sapiens attractin protein.
Length = 1272
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AF218915-1|AAF72881.1| 1429|Homo sapiens membrane attractin
precursor protein.
Length = 1429
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AF218910-1|AAF72882.1| 1272|Homo sapiens secreted attractin
precursor protein.
Length = 1272
Score = 63.3 bits (147), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSDTVECECSENWKGEACDIPHCTDNCG 292
Score = 58.0 bits (134), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSDTVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AB208957-1|BAD92194.1| 793|Homo sapiens suppression of
tumorigenicity variant protein.
Length = 793
Score = 63.3 bits (147), Expect = 3e-09
Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 226 YPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAF 285
YP NC W I A P IT++F FD++G+ + C D +T+ + + R
Sbjct: 4 YPAKINCSWFIRANPGEIITISFQDFDIQGS----RRCNLDWLTIETYKNIESYRA---- 55
Query: 286 CGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGC-QHECHN 340
CG+ +PPP S + ++F SD ++ R GF Y+ E E N C Q C N
Sbjct: 56 CGSTIPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSE--EPNCACDQFRCGN 109
Score = 62.1 bits (144), Expect = 6e-09
Identities = 46/141 (32%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Query: 183 GGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQH 242
G +C D+G E+ D CG L GT SP++P+ YPP NC W I
Sbjct: 175 GNIDCL-DLGDEIDCDVP----TCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHR 229
Query: 243 RITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLR 302
++ L FT F L+G YD + + +LR AF A P V S +R
Sbjct: 230 KVILRFTDFKLDGTGYGDYVKIYDGLEENPH---KLLRVLTAFDSHA-PLTVVSSSGQIR 285
Query: 303 VQFTSDGSVHRSGFAAVYYID 323
V F +D GF A Y +D
Sbjct: 286 VHFCADKVNAARGFNATYQVD 306
Score = 54.8 bits (126), Expect = 9e-07
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 387 YPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASADVKTLGIFCGSKL 446
YPA+ +C W PG I + F F+++ + C D +TI + + CGS +
Sbjct: 4 YPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRA---CGSTI 60
Query: 447 PHLVMASQNQMYMVFKSDGSVQRKGF 472
P ++SQ+ +++ F SD ++ RKGF
Sbjct: 61 PPPYISSQDHIWIRFHSDDNISRKGF 86
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 7/120 (5%)
Query: 361 DCKEGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQEC 420
DC C + +GT SPNYP YP +C W T ++ L F F+L+
Sbjct: 187 DCDVPTCGQWLKYFYGTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLD---GT 243
Query: 421 AY-DHVTIYDGASADV-KTLGIFCG--SKLPHLVMASQNQMYMVFKSDGSVQRKGFLATH 476
Y D+V IYDG + K L + S P V++S Q+ + F +D +GF AT+
Sbjct: 244 GYGDYVKIYDGLEENPHKLLRVLTAFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATY 303
Score = 53.2 bits (122), Expect = 3e-06
Identities = 22/90 (24%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFCGIKM 563
Y ++ +C W I A + ++F F+++ C D++ + CG +
Sbjct: 4 YPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRA---CGSTI 60
Query: 564 PPEIVSTSEALLVRFRTDDSLVFKGFSASY 593
PP +S+ + + +RF +DD++ KGF +Y
Sbjct: 61 PPPYISSQDHIWIRFHSDDNISRKGFRLAY 90
Score = 50.8 bits (116), Expect = 1e-05
Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 9/106 (8%)
Query: 60 GHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDS 119
G SPNYPD Y P C W + +V LRF F+++ T D VK+ DG ++
Sbjct: 202 GTFNSPNYPDFYPPGSNCTWLIDTGDHRKVILRFTDFKLDG--TGYGDYVKIYDG-LEEN 258
Query: 120 P-----LIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATF 160
P ++ F H P + S+S ++ V F +D GF+AT+
Sbjct: 259 PHKLLRVLTAFDSH-APLTVVSSSGQIRVHFCADKVNAARGFNATY 303
Score = 42.3 bits (95), Expect = 0.005
Identities = 25/114 (21%), Positives = 46/114 (40%), Gaps = 7/114 (6%)
Query: 70 DYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKVKVRDGDSMDSPLIGMFCGHK 129
DY C W + + + F F+++ C+ D + + +++S CG
Sbjct: 3 DYPAKINCSWFIRANPGEIITISFQDFDIQGSRRCNLDWLTIETYKNIESYRA---CGST 59
Query: 130 IPPDIRSTSNKLLVIFESDSTVQKAGFSATFM---KEFDECASIDHGCSH-SCV 179
IPP S+ + + + F SD + + GF + E CA C + C+
Sbjct: 60 IPPPYISSQDHIWIRFHSDDNISRKGFRLAYFSGKSEEPNCACDQFRCGNGKCI 113
Score = 31.9 bits (69), Expect = 7.2
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 504 YESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXX---XXXXXTFCG 560
Y ++C W I+ + V L F F+L+ DYV+++ T
Sbjct: 213 YPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYG--DYVKIYDGLEENPHKLLRVLTAFD 270
Query: 561 IKMPPEIVSTSEALLVRFRTDDSLVFKGFSASYQM 595
P +VS+S + V F D +GF+A+YQ+
Sbjct: 271 SHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQV 305
>AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 167 CASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN---ACGGALYGPNGTITSPSFP 223
CA+ + C H C G C C +GY+L +DGK CE+ G +G + +
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-- 200
Query: 224 ELYPPLKNCLWEIVAPPQ--HRITLNFTHFDLEGNHMYQQECEYDSV----TVHSKLGAD 277
+ + + +E+ A + +RI + + N C + S T D
Sbjct: 201 -SFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 259
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC--------AE 329
+R T + +D + T++ + G A Y + D C A
Sbjct: 260 TDQR------TCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 313
Query: 330 NNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+ GGC+H C N G ++C+C +G+ LH ++ C
Sbjct: 314 SRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 61.3 bits (142), Expect = 1e-08
Identities = 27/55 (49%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
DVDEC +NGGCQH C NT G Y C C GF LH + C GGC+H
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 110
Score = 55.6 bits (128), Expect = 5e-07
Identities = 19/41 (46%), Positives = 26/41 (63%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECAS GC H C N G ++C+C+ GY LH D + C
Sbjct: 306 EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 53.6 bits (123), Expect = 2e-06
Identities = 19/41 (46%), Positives = 29/41 (70%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECA+ C+H C+NT G ++C C GYEL +DG++C
Sbjct: 179 EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 219
Score = 52.8 bits (121), Expect = 4e-06
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + GC H CVNT G Y C C G+ LH+D + C
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTC 95
Score = 51.6 bits (118), Expect = 8e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 10/79 (12%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKHDVTL 373
IDVD+CA++ CQ C N GGYEC C++G+ L + C++ GGC+H T
Sbjct: 266 IDVDDCADSPC-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTN 324
Query: 374 PHGTIFSPNYPAAYPARKD 392
G+ F + A Y +D
Sbjct: 325 LAGS-FQCSCEAGYRLHED 342
Score = 45.2 bits (102), Expect = 7e-04
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ D+CA C C N GGYEC C GY L +DG CE+
Sbjct: 267 DVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCED 307
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 161 MKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
M+ + C + + GCSH C +T G C C GYEL +D + C
Sbjct: 224 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC 265
Score = 40.7 bits (91), Expect = 0.015
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 324 VDECAENNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDC 362
++ CA NGGCQH C T+ + C C GF L + C
Sbjct: 98 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 137
Score = 38.7 bits (86), Expect = 0.063
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
CA NG C H C G C CH G+ L + C++
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 180
Score = 38.3 bits (85), Expect = 0.083
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHSCVN-TLGGYECACDIGYELHSDGKKC 202
+ CA + GC H CV T+ + C C G++L DG+ C
Sbjct: 99 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 137
>AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domains
6 protein.
Length = 1229
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 167 CASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN---ACGGALYGPNGTITSPSFP 223
CA+ + C H C G C C +GY+L +DGK CE+ G +G + +
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-- 200
Query: 224 ELYPPLKNCLWEIVAPPQ--HRITLNFTHFDLEGNHMYQQECEYDSV----TVHSKLGAD 277
+ + + +E+ A + +RI + + N C + S T D
Sbjct: 201 -SFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 259
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC--------AE 329
+R T + +D + T++ + G A Y + D C A
Sbjct: 260 TDQR------TCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 313
Query: 330 NNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+ GGC+H C N G ++C+C +G+ LH ++ C
Sbjct: 314 SRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 61.3 bits (142), Expect = 1e-08
Identities = 27/55 (49%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
DVDEC +NGGCQH C NT G Y C C GF LH + C GGC+H
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 110
Score = 55.6 bits (128), Expect = 5e-07
Identities = 19/41 (46%), Positives = 26/41 (63%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECAS GC H C N G ++C+C+ GY LH D + C
Sbjct: 306 EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 346
Score = 53.6 bits (123), Expect = 2e-06
Identities = 19/41 (46%), Positives = 29/41 (70%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECA+ C+H C+NT G ++C C GYEL +DG++C
Sbjct: 179 EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 219
Score = 52.8 bits (121), Expect = 4e-06
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + GC H CVNT G Y C C G+ LH+D + C
Sbjct: 56 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTC 95
Score = 51.6 bits (118), Expect = 8e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 10/79 (12%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKHDVTL 373
IDVD+CA++ CQ C N GGYEC C++G+ L + C++ GGC+H T
Sbjct: 266 IDVDDCADSPC-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTN 324
Query: 374 PHGTIFSPNYPAAYPARKD 392
G+ F + A Y +D
Sbjct: 325 LAGS-FQCSCEAGYRLHED 342
Score = 45.2 bits (102), Expect = 7e-04
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ D+CA C C N GGYEC C GY L +DG CE+
Sbjct: 267 DVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCED 307
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 161 MKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
M+ + C + + GCSH C +T G C C GYEL +D + C
Sbjct: 224 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC 265
Score = 40.7 bits (91), Expect = 0.015
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 324 VDECAENNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDC 362
++ CA NGGCQH C T+ + C C GF L + C
Sbjct: 98 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 137
Score = 38.7 bits (86), Expect = 0.063
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
CA NG C H C G C CH G+ L + C++
Sbjct: 143 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 180
Score = 38.3 bits (85), Expect = 0.083
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHSCVN-TLGGYECACDIGYELHSDGKKC 202
+ CA + GC H CV T+ + C C G++L DG+ C
Sbjct: 99 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 137
>AF106861-1|AAD03057.1| 1272|Homo sapiens attractin-2 protein.
Length = 1272
Score = 62.9 bits (146), Expect = 3e-09
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 17/168 (10%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
CGG + + + P +Y+ C W + + + LRF+ F E CS+D +
Sbjct: 132 CGGRFRLTGSSGFVTDG-PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHL 186
Query: 110 KVRDGDSMDSPLIGMFCGHKIP--------PDIRSTSNKLLVIFESDSTVQKAGFSATFM 161
V DGDS+ +PL+ F G +P P++ +TS L+ F SD+ GF+ T+
Sbjct: 187 YVYDGDSIYAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY- 245
Query: 162 KEFDECASIDHGCSHSCV-NTLGGYECACDIGYELHS-DGKKCENACG 207
FD C + G + N+ EC C ++ + D C + CG
Sbjct: 246 -SFDMCPNNCSGRGECKISNSSETVECECSENWKGEACDIPHCTDNCG 292
Score = 57.6 bits (133), Expect = 1e-07
Identities = 63/220 (28%), Positives = 93/220 (42%), Gaps = 32/220 (14%)
Query: 141 LLVIFESDSTVQKAGFSATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGK 200
LL+ E+++ A S + E EC D C + G +C C G+ G+
Sbjct: 75 LLLPCEAEAAAAAAAVSGSAAAEAKEC---DRPCVNGGRCNPGTGQCVCPAGWV----GE 127
Query: 201 KCENACGGA--LYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLE--GN 256
+C++ CGG L G +G +T P Y C W I P + L F HF E +
Sbjct: 128 QCQH-CGGRFRLTGSSGFVTDG--PGNYKYKTKCTWLIEGQPNRIMRLRFNHFATECSWD 184
Query: 257 HMYQQECEYDSVTVHSKL-----GADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSV 311
H+Y YD ++++ L G V R G +P V + G L + F SD +
Sbjct: 185 HLY----VYDGDSIYAPLVAAFSGLIVPERDG---NETVPEVVATSGYAL-LHFFSDAAY 236
Query: 312 HRSGFAAVYYIDVDECAENNGGCQHEC--HNTLGGYECAC 349
+ +GF Y D+ C N G + EC N+ EC C
Sbjct: 237 NLTGFNITYSFDM--CPNNCSG-RGECKISNSSETVECEC 273
Score = 51.2 bits (117), Expect = 1e-05
Identities = 50/187 (26%), Positives = 72/187 (38%), Gaps = 25/187 (13%)
Query: 314 SGFAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHDVTL 373
SG AA + D N G C G +C C +G+ C+ G + +T
Sbjct: 91 SGSAAAEAKECDRPCVNGGRCNP------GTGQCVCPAGWV----GEQCQHCGGRFRLTG 140
Query: 374 PHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPHQECAYDHVTIYDGASA 433
G F + P Y + C W P ++L FN F E C++DH+ +YDG S
Sbjct: 141 SSG--FVTDGPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSI 194
Query: 434 DVKTLGIFCGSKLPHL--------VMASQNQMYMVFKSDGSVQRKGFLATHS-TACGGYL 484
+ F G +P V+A+ + F SD + GF T+S C
Sbjct: 195 YAPLVAAFSGLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITYSFDMCPNNC 254
Query: 485 SATEEVK 491
S E K
Sbjct: 255 SGRGECK 261
Score = 44.0 bits (99), Expect = 0.002
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 12/102 (11%)
Query: 500 GDNAYESRADCDWNIEAPRNHFVKLTFLTFELEREANCRYDYVQVFXXXXXXXXXXXTFC 559
G Y+ + C W IE N ++L F F E C +D++ V+ F
Sbjct: 148 GPGNYKYKTKCTWLIEGQPNRIMRLRFNHFATE----CSWDHLYVYDGDSIYAPLVAAFS 203
Query: 560 GIKMP--------PEIVSTSEALLVRFRTDDSLVFKGFSASY 593
G+ +P PE+V+TS L+ F +D + GF+ +Y
Sbjct: 204 GLIVPERDGNETVPEVVATSGYALLHFFSDAAYNLTGFNITY 245
>AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein
protein.
Length = 1640
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 167 CASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN---ACGGALYGPNGTITSPSFP 223
CA+ + C H C G C C +GY+L +DGK CE+ G +G + +
Sbjct: 323 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-- 380
Query: 224 ELYPPLKNCLWEIVAPPQ--HRITLNFTHFDLEGNHMYQQECEYDSV----TVHSKLGAD 277
+ + + +E+ A + +RI + + N C + S T D
Sbjct: 381 -SFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 439
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC--------AE 329
+R T + +D + T++ + G A Y + D C A
Sbjct: 440 TDQR------TCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 493
Query: 330 NNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+ GGC+H C N G ++C+C +G+ LH ++ C
Sbjct: 494 SRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 526
Score = 61.3 bits (142), Expect = 1e-08
Identities = 27/55 (49%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
DVDEC +NGGCQH C NT G Y C C GF LH + C GGC+H
Sbjct: 236 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 290
Score = 55.6 bits (128), Expect = 5e-07
Identities = 19/41 (46%), Positives = 26/41 (63%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECAS GC H C N G ++C+C+ GY LH D + C
Sbjct: 486 EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 526
Score = 53.6 bits (123), Expect = 2e-06
Identities = 19/41 (46%), Positives = 29/41 (70%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECA+ C+H C+NT G ++C C GYEL +DG++C
Sbjct: 359 EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 399
Score = 52.8 bits (121), Expect = 4e-06
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + GC H CVNT G Y C C G+ LH+D + C
Sbjct: 236 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTC 275
Score = 51.6 bits (118), Expect = 8e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 10/79 (12%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKHDVTL 373
IDVD+CA++ CQ C N GGYEC C++G+ L + C++ GGC+H T
Sbjct: 446 IDVDDCADSPC-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTN 504
Query: 374 PHGTIFSPNYPAAYPARKD 392
G+ F + A Y +D
Sbjct: 505 LAGS-FQCSCEAGYRLHED 522
Score = 45.2 bits (102), Expect = 7e-04
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ D+CA C C N GGYEC C GY L +DG CE+
Sbjct: 447 DVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCED 487
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 161 MKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
M+ + C + + GCSH C +T G C C GYEL +D + C
Sbjct: 404 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC 445
Score = 40.7 bits (91), Expect = 0.015
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 324 VDECAENNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDC 362
++ CA NGGCQH C T+ + C C GF L + C
Sbjct: 278 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 317
Score = 38.7 bits (86), Expect = 0.063
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
CA NG C H C G C CH G+ L + C++
Sbjct: 323 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 360
Score = 38.3 bits (85), Expect = 0.083
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHSCVN-TLGGYECACDIGYELHSDGKKC 202
+ CA + GC H CV T+ + C C G++L DG+ C
Sbjct: 279 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 317
>AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein.
Length = 1246
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/213 (23%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 167 CASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN---ACGGALYGPNGTITSPSFP 223
CA+ + C H C G C C +GY+L +DGK CE+ G +G + +
Sbjct: 160 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG-- 217
Query: 224 ELYPPLKNCLWEIVAPPQ--HRITLNFTHFDLEGNHMYQQECEYDSV----TVHSKLGAD 277
+ + + +E+ A + +RI + + N C + S T D
Sbjct: 218 -SFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELD 276
Query: 278 VLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYIDVDEC--------AE 329
+R T + +D + T++ + G A Y + D C A
Sbjct: 277 TDQR------TCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECAS 330
Query: 330 NNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
+ GGC+H C N G ++C+C +G+ LH ++ C
Sbjct: 331 SRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 363
Score = 61.3 bits (142), Expect = 1e-08
Identities = 27/55 (49%), Positives = 30/55 (54%), Gaps = 8/55 (14%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC--------KEGGCKH 369
DVDEC +NGGCQH C NT G Y C C GF LH + C GGC+H
Sbjct: 73 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQH 127
Score = 55.6 bits (128), Expect = 5e-07
Identities = 19/41 (46%), Positives = 26/41 (63%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECAS GC H C N G ++C+C+ GY LH D + C
Sbjct: 323 EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGC 363
Score = 53.6 bits (123), Expect = 2e-06
Identities = 19/41 (46%), Positives = 29/41 (70%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
++ DECA+ C+H C+NT G ++C C GYEL +DG++C
Sbjct: 196 EDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 236
Score = 52.8 bits (121), Expect = 4e-06
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
+ DEC + + GC H CVNT G Y C C G+ LH+D + C
Sbjct: 73 DVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTC 112
Score = 51.6 bits (118), Expect = 8e-06
Identities = 29/79 (36%), Positives = 42/79 (53%), Gaps = 10/79 (12%)
Query: 322 IDVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE--------GGCKHDVTL 373
IDVD+CA++ CQ C N GGYEC C++G+ L + C++ GGC+H T
Sbjct: 283 IDVDDCADSPC-CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTN 341
Query: 374 PHGTIFSPNYPAAYPARKD 392
G+ F + A Y +D
Sbjct: 342 LAGS-FQCSCEAGYRLHED 359
Score = 45.2 bits (102), Expect = 7e-04
Identities = 19/42 (45%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 163 EFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
+ D+CA C C N GGYEC C GY L +DG CE+
Sbjct: 284 DVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCED 324
Score = 42.7 bits (96), Expect = 0.004
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 161 MKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC 202
M+ + C + + GCSH C +T G C C GYEL +D + C
Sbjct: 241 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTC 282
Score = 40.7 bits (91), Expect = 0.015
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 324 VDECAENNGGCQHEC-HNTLGGYECACHSGFTLHPNKHDC 362
++ CA NGGCQH C T+ + C C GF L + C
Sbjct: 115 INSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 154
Score = 38.7 bits (86), Expect = 0.063
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 327 CAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
CA NG C H C G C CH G+ L + C++
Sbjct: 160 CANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACED 197
Score = 38.3 bits (85), Expect = 0.083
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 165 DECASIDHGCSHSCVN-TLGGYECACDIGYELHSDGKKC 202
+ CA + GC H CV T+ + C C G++L DG+ C
Sbjct: 116 NSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHC 154
>AK131282-1|BAD18457.1| 872|Homo sapiens protein ( Homo sapiens
cDNA FLJ16233 fis, clone FEBRA2028256, moderately
similar to FIBRILLIN 2 PRECURSOR. ).
Length = 872
Score = 62.5 bits (145), Expect = 4e-09
Identities = 60/210 (28%), Positives = 78/210 (37%), Gaps = 24/210 (11%)
Query: 157 SATFMKEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC---------ENACG 207
+AT + DEC+ + C+ C NT G + C+C GY L DG+ C ++ C
Sbjct: 505 TATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSRQHNCQ 564
Query: 208 GALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDS 267
G T P + C HR + L G Y+ C
Sbjct: 565 FLCVNTVGAFTCRCPPGFTQHHQACFDVNECDGPHRCQHGCQN-QLGG---YRCSCP-QG 619
Query: 268 VTVHSKLGADVLRRHGAFCGTALPPPVTSDGSVLRVQFTSDGSVHRSGFAAVYYI----D 323
T HS+ V C AL PP S R V SGF + D
Sbjct: 620 FTQHSQWAQCVDENE---C--ALSPPTCGSASC-RNTLGGFRCVCPSGFDFDQALGGCQD 673
Query: 324 VDECAENNGGCQHECHNTLGGYECACHSGF 353
VDECA G C + C NT GG+ C C G+
Sbjct: 674 VDECAGRRGPCSYSCANTPGGFLCGCPQGY 703
Score = 48.4 bits (110), Expect = 8e-05
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDC 362
DV+EC + CQH C N LGGY C+C GFT H C
Sbjct: 591 DVNEC-DGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQC 629
Score = 47.2 bits (107), Expect = 2e-04
Identities = 24/56 (42%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 155 GFSATFMKEFD--ECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKC--ENAC 206
GF+ FD EC H C H C N LGGY C+C G+ HS +C EN C
Sbjct: 581 GFTQHHQACFDVNECDG-PHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENEC 635
Score = 46.8 bits (106), Expect = 2e-04
Identities = 18/42 (42%), Positives = 25/42 (59%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLHPNKHDCKE 364
D+DEC+ N C CHNT G Y C C +G+TL + C++
Sbjct: 272 DIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 313
Score = 43.6 bits (98), Expect = 0.002
Identities = 16/34 (47%), Positives = 19/34 (55%)
Query: 323 DVDECAENNGGCQHECHNTLGGYECACHSGFTLH 356
D+DEC CQ C NT+G + C C GFT H
Sbjct: 552 DLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQH 585
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/204 (22%), Positives = 72/204 (35%), Gaps = 15/204 (7%)
Query: 165 DECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGTITSPSFP 223
+EC + C + CVNT G + C CD G++ +C + G + S
Sbjct: 360 NECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLS 419
Query: 224 ELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQQECEYDSVTVHSKLGADVLRRHG 283
+ E L G Y++ C + S D R
Sbjct: 420 SSSEAVTRA--ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLA 477
Query: 284 AFCGTALPPPVTSDGSV---LRVQFTSDGSVHRSGFAAVYYIDVDECAENNGGCQHECHN 340
C A + S GS + +T D + A +D+DEC++ C C N
Sbjct: 478 HLC--AHGECINSLGSFRCHCQAGYTPDAT-------ATTCLDMDECSQVPKPCTFLCKN 528
Query: 341 TLGGYECACHSGFTLHPNKHDCKE 364
T G + C+C G+ L + CK+
Sbjct: 529 TKGSFLCSCPRGYLLEEDGRTCKD 552
Score = 42.3 bits (95), Expect = 0.005
Identities = 16/38 (42%), Positives = 22/38 (57%)
Query: 316 FAAVYYIDVDECAENNGGCQHECHNTLGGYECACHSGF 353
F + +D DEC+ + Q C N +GG+ECAC GF
Sbjct: 225 FTGINCVDTDECSVGHPCGQGTCTNVIGGFECACADGF 262
Score = 42.3 bits (95), Expect = 0.005
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCEN 204
++ DEC+ C+ C NT G Y C C GY L DG C +
Sbjct: 271 EDIDECSLNPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 313
Score = 41.9 bits (94), Expect = 0.007
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ DEC + H C+H C+N+LG + C C GY + C
Sbjct: 468 RDVDECRMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTC 509
Score = 41.5 bits (93), Expect = 0.009
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 162 KEFDECASIDHGCSHSCVNTLGGYECACDIGYELHSDGKKCENACGGALYGPNGT 216
++ DECA CS+SC NT GG+ C C GY G C + G + GP T
Sbjct: 672 QDVDECAGRRGPCSYSCANTPGGFLCGCPQGYFRAGQG-HCVSGLGFS-PGPQDT 724
Score = 39.5 bits (88), Expect = 0.036
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Query: 165 DECASIDHGCSH-SCVNTLGGYECACDIGYE 194
DEC S+ H C +C N +GG+ECAC G+E
Sbjct: 234 DEC-SVGHPCGQGTCTNVIGGFECACADGFE 263
Score = 39.1 bits (87), Expect = 0.047
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 322 IDVDECAENNGGC-QHECHNTLGGYECACHSGFTLHPNKHDCKE 364
+D +ECA + C C NTLGG+ C C SGF C++
Sbjct: 630 VDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALGGCQD 673
Score = 38.7 bits (86), Expect = 0.063
Identities = 17/34 (50%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTL 355
DV+ECAEN G C + C NT G + C C G++L
Sbjct: 190 DVNECAENPGVCTNGVCVNTDGSFRCECPFGYSL 223
Score = 37.1 bits (82), Expect = 0.19
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 162 KEFDECASIDHGCSHS-CVNTLGGYECACDIGYELHSDGKKC 202
++ +ECA C++ CVNT G + C C GY L G C
Sbjct: 189 EDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINC 230
Score = 33.9 bits (74), Expect = 1.8
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 7/51 (13%)
Query: 323 DVDECAENNGGCQH---ECHNTLGGYECACHSGFTLHPNKHDCKEGGCKHD 370
DVDECA+ C EC N +G + C C G P + GC D
Sbjct: 313 DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGE----GCTDD 359
Score = 33.5 bits (73), Expect = 2.4
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 323 DVDECAENNGGCQH-ECHNTLGGYECACHSGFTLHPNK---HDCKEGGCKHDV 371
D +EC C + C NT G + C C GF P HD ++G C +V
Sbjct: 358 DDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEV 410
>AY038048-1|AAK71497.1| 996|Homo sapiens SEZ6 protein.
Length = 996
Score = 60.9 bits (141), Expect = 1e-08
Identities = 53/223 (23%), Positives = 93/223 (41%), Gaps = 29/223 (13%)
Query: 50 CGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYDKV 109
C G I + G + SP +P +Y N C W L P+ ++ L F + D D++
Sbjct: 418 CPGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRL 473
Query: 110 KVRDGDSMDS-PLIGMFCGHKIPPD-IRSTSNKLLVIFESDSTVQKAGFSATFMK-EFDE 166
+R+GD++++ P+ + +P + + S+ V +DS+ AG + + +
Sbjct: 474 IIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGH 533
Query: 167 CAS--IDHGCSHSCVNT--LG-GYECACDIGYELHSDG-----------------KKCEN 204
C + +G S T +G E +CD GY L C
Sbjct: 534 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 593
Query: 205 ACGGALYGPNGTITSPSFPELYPPLKNCLWEIVAPPQHRITLN 247
C G + G + SP++PE Y ++C+W + RI L+
Sbjct: 594 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD 636
Score = 59.3 bits (137), Expect = 4e-08
Identities = 68/295 (23%), Positives = 105/295 (35%), Gaps = 37/295 (12%)
Query: 202 CENACGGALYGPN-GTITSPSFPELYPPLKNCLWEIVAPPQHRITLNFTHFDLEGNHMYQ 260
C C G + G I SP FP Y C W + AP R+ L+F L +
Sbjct: 414 CIGECPGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD--- 470
Query: 261 QECEYDSVTVHSKLGADVLRRHGAFCGTALP-PPVTSDGSVLRVQFTSDGSVHRSGFAAV 319
D + + + + + ++ LP + S G V+ ++D S +G A
Sbjct: 471 -----DRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALR 525
Query: 320 YY-IDVDECAE-----NNGGCQHECHNTLGGYECACHSGFTLHPNK--------HDCK-- 363
Y C E N + E +C G+TL HD +
Sbjct: 526 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWN 585
Query: 364 ------EGGCKHDVTLPHGTIFSPNYPAAYPARKDCVWQFSTTPGHRIKLIFNVFELEPH 417
C ++T G + SPN+P Y +DC+W RI L V + P
Sbjct: 586 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 645
Query: 418 QECAYDHVTIYDGASADVKTLGIFCGSKLPHLVMASQNQMYMVFKSDGSVQRKGF 472
D +T YDG + LG + G + + S + + F+SD G+
Sbjct: 646 -----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGY 695
Score = 54.8 bits (126), Expect = 9e-07
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Query: 48 AVCGGDIEVDSNGHLESPNYPDDYQPNKLCIWKLSVPQDYQVALRFHSFEVENHDTCSYD 107
AVC G+I DS G + SPN+P+ Y + CIW + V +D ++ L + D ++
Sbjct: 593 AVCSGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF- 650
Query: 108 KVKVRDGDSMDSPLIGMFCGHKIPPDIRSTSNKLLVIFESDSTVQKAGFSATFMKEFDE 166
DGD + + ++G + G + + ++ + + F+SD G+ F+ F E
Sbjct: 651 ----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 705
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.138 0.445
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,723,204
Number of Sequences: 224733
Number of extensions: 4715164
Number of successful extensions: 18998
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 680
Number of HSP's successfully gapped in prelim test: 214
Number of HSP's that attempted gapping in prelim test: 7318
Number of HSP's gapped (non-prelim): 9120
length of query: 642
length of database: 73,234,838
effective HSP length: 95
effective length of query: 547
effective length of database: 51,885,203
effective search space: 28381206041
effective search space used: 28381206041
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 68 (31.5 bits)
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