Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002508-TA|BGIBMGA002508-PA|IPR001697|Pyruvate kinase
(623 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k... 642 0.0
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu... 625 e-178
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py... 504 e-141
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ... 503 e-141
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R... 500 e-140
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 491 e-137
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P... 466 e-130
UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;... 440 e-122
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis... 433 e-120
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6... 423 e-117
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re... 405 e-111
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis... 396 e-108
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ... 395 e-108
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P... 393 e-108
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla... 380 e-104
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep... 377 e-103
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol... 375 e-102
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep... 369 e-100
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis... 364 4e-99
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof... 362 1e-98
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism... 343 9e-93
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ... 342 2e-92
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 338 2e-91
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc... 338 3e-91
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R... 337 6e-91
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr... 333 7e-90
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ... 333 9e-90
UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi... 332 1e-89
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=... 332 2e-89
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale... 331 3e-89
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k... 331 4e-89
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac... 326 8e-88
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc... 321 3e-86
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr... 321 3e-86
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact... 318 3e-85
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P... 318 4e-85
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|... 317 5e-85
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 316 2e-84
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ... 316 2e-84
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea... 314 5e-84
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|... 313 8e-84
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 312 1e-83
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|... 312 2e-83
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R... 311 3e-83
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ... 310 1e-82
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci... 309 2e-82
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube... 307 5e-82
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan... 306 9e-82
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R... 305 2e-81
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran... 304 4e-81
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis... 304 4e-81
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re... 302 1e-80
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep... 301 3e-80
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce... 301 3e-80
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte... 301 5e-80
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop... 300 6e-80
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae... 299 2e-79
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (... 298 3e-79
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact... 297 4e-79
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|... 297 7e-79
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis... 295 2e-78
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re... 294 4e-78
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr... 294 5e-78
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep... 293 7e-78
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte... 293 7e-78
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py... 293 1e-77
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R... 292 2e-77
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py... 291 3e-77
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ... 291 3e-77
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ... 288 3e-76
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 286 1e-75
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R... 286 1e-75
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett... 285 2e-75
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c... 285 2e-75
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme... 284 4e-75
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,... 282 2e-74
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.... 281 5e-74
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 279 1e-73
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n... 279 2e-73
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re... 278 3e-73
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re... 274 5e-72
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ... 274 6e-72
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism... 273 1e-71
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba... 270 7e-71
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ... 269 1e-70
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P... 269 2e-70
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter... 269 2e-70
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re... 268 2e-70
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae... 268 3e-70
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae... 268 3e-70
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter... 266 1e-69
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re... 266 1e-69
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ... 265 2e-69
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari... 265 3e-69
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr... 264 4e-69
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R... 264 4e-69
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace... 262 1e-68
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ... 256 1e-66
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism... 255 3e-66
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m... 250 6e-65
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ... 244 7e-63
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne... 243 1e-62
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf... 242 2e-62
UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 239 2e-61
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:... 239 2e-61
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno... 233 8e-60
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae... 231 6e-59
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende... 230 1e-58
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales... 229 1e-58
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr... 228 3e-58
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:... 228 3e-58
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ... 227 5e-58
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun... 227 9e-58
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P... 222 3e-56
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|... 218 4e-55
UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|R... 215 2e-54
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R... 214 5e-54
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep... 214 5e-54
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran... 211 4e-53
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty... 206 1e-51
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m... 204 4e-51
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A... 203 1e-50
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum... 174 5e-42
UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga maquil... 167 1e-39
UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containi... 165 4e-39
UniRef50_A3EXR5 Cluster: Pyruvate kinase-like protein; n=2; Coel... 164 7e-39
UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containi... 163 2e-38
UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep: ... 150 1e-34
UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archae... 146 2e-33
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w... 144 6e-33
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola... 141 6e-32
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten... 139 2e-31
UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep: Py... 138 4e-31
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R... 134 7e-30
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno... 130 1e-28
UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter jej... 129 2e-28
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P... 128 4e-28
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije... 125 3e-27
UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2; Alphaproteobacter... 120 1e-25
UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium perfr... 119 3e-25
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali... 117 1e-24
UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium tetrau... 116 2e-24
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py... 116 2e-24
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba... 115 4e-24
UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.... 113 1e-23
UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter sphae... 113 1e-23
UniRef50_Q5D8L3 Cluster: SJCHGC03591 protein; n=1; Schistosoma j... 113 1e-23
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr... 113 2e-23
UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate k... 111 4e-23
UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep... 111 5e-23
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua... 111 7e-23
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep... 110 1e-22
UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia intestina... 107 1e-21
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ... 104 6e-21
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz... 104 8e-21
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep... 103 1e-20
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ... 100 2e-19
UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|R... 98 5e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil... 97 9e-19
UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba ... 91 1e-16
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon... 89 3e-16
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k... 89 4e-16
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker... 83 2e-14
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ... 82 5e-14
UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium tum... 71 1e-10
UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P... 64 1e-08
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri... 64 1e-08
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel... 60 1e-07
UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida albicans|... 54 1e-05
UniRef50_A4BH87 Cluster: Pyruvate kinase; n=1; Reinekea sp. MED2... 49 4e-04
UniRef50_Q2Y8W2 Cluster: Pyruvate kinase; n=1; Nitrosospira mult... 48 7e-04
UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re... 44 0.009
UniRef50_A7QZT2 Cluster: Chromosome chr13 scaffold_286, whole ge... 43 0.021
UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267, w... 43 0.021
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden... 43 0.028
UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep: CG1222... 42 0.037
UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium BA... 39 0.35
UniRef50_Q3ZYI6 Cluster: Transcription-repair coupling factor; n... 39 0.46
UniRef50_UPI00006CB055 Cluster: hypothetical protein TTHERM_0023... 37 1.4
UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep: ... 36 2.4
UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium c... 36 4.3
UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyosteli... 36 4.3
UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ... 35 5.6
UniRef50_A6G647 Cluster: SNF2/helicase domain protein; n=1; Ples... 35 7.5
UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3; ... 35 7.5
UniRef50_UPI00005082DC Cluster: PREDICTED: similar to Pyruvate k... 34 9.9
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding... 34 9.9
UniRef50_Q9SZT8 Cluster: Putative uncharacterized protein F6G17.... 34 9.9
UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia stipitis... 34 9.9
>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
similar to Pyruvate kinase (PK) - Tribolium castaneum
Length = 557
Score = 642 bits (1585), Expect = 0.0
Identities = 290/514 (56%), Positives = 377/514 (73%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
+QL H LDI S +RL+GIICT+GP++ +V LE+M+E GMN+AR+ SHG+ E H
Sbjct: 32 TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 209
E I+N R A ++YS +LG + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92 TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151
Query: 210 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLG 269
Y EKG++ IYVDY NI VV+PGNRIF+DDGLIS+IC SV LTC++ENGGMLG
Sbjct: 152 DKAYLEKGSSSVIYVDYDNIQKVVQPGNRIFLDDGLISLICTSVQGSVLTCSVENGGMLG 211
Query: 270 SRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN 329
S K VNLPGI +DLP VSEKDK DLLFGVE G+D + ASFIRN + E+R +LG G
Sbjct: 212 SCKNVNLPGIDIDLPVVSEKDKEDLLFGVEHGIDTVHASFIRNAVDVSEVRDVLGRAGNK 271
Query: 330 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPV 389
I IISKIENHQG+ N+DEII SDGIM+ RGDL +EI PEK+FLAQK++IA+CN+ GKPV
Sbjct: 272 ILIISKIENHQGVHNIDEIIKASDGIMIGRGDLAVEIGPEKLFLAQKSIIAKCNKAGKPV 331
Query: 390 ICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKE 449
ICA Q+L SM+K+PRPTRAE +DVANA+LDG DCVML+GET G +P+EC+ + ICKE
Sbjct: 332 ICANQLLYSMIKRPRPTRAECTDVANAVLDGVDCVMLTGETFLGQHPIECIRAASKICKE 391
Query: 450 AEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKY 509
AE IW++ F +L+ +PP++ +CLA+AI+V + SG+SAH L+KY
Sbjct: 392 AEGAIWYKHHFRELIGHARPPLETSHTICIAAVEAANQCLAAAIIVTSVSGRSAHSLAKY 451
Query: 510 RPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVH 569
RP CPII VTR P A+Q +L+RG++P+ Y+ DW +D++ R+ G+ FG+ RGFV
Sbjct: 452 RPNCPIILVTRDPTVAKQANLFRGIIPLFYEVERKDDWRRDIEARISFGISFGKWRGFVR 511
Query: 570 PGDNAVVVTGWKQGSGFTNTVRVMLVQSASMHTD 603
GD V V G ++GSG+T+T+RV+ V + D
Sbjct: 512 SGDPIVAVNGSQRGSGYTDTIRVLYVMRPIVEGD 545
>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
Homo sapiens (Human)
Length = 574
Score = 625 bits (1545), Expect = e-178
Identities = 300/507 (59%), Positives = 376/507 (74%), Gaps = 6/507 (1%)
Query: 92 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 151
L+H+C LDIDS+ R + II TIGPASR+V L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70 LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129
Query: 152 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 208
+I N REA +S++ GSP S +AIALDTKGPEIRTG+L+GG +EVEL KG + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186
Query: 209 TSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGML 268
++ +GNA+T++VDY NI VV G RI+IDDGLIS++ Q + + L +ENGG+L
Sbjct: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVL 246
Query: 269 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK 328
GSRKGVNLPG VDLP +SE+D DL FGVE GVD++FASF+R + + +R LG +G
Sbjct: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306
Query: 329 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
IKIISKIENH+G+ DEI+ SDGIMVARGDLGIEIP EKVFLAQK MI RCN GKP
Sbjct: 307 GIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKP 366
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
V+CATQMLESM+ KPRPTRAE SDVANA+LDGADC+MLSGETAKG++PVE V I +
Sbjct: 367 VVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAR 426
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
EAEA ++HRQLF +L DP KC A+AI+V+TT+G+SA LLS+
Sbjct: 427 EAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSR 486
Query: 509 YRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFV 568
YRPR +IAVTR Q ARQVHL RGV P++Y+EP + W DVD RVQ G+ G+ RGF+
Sbjct: 487 YRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFL 546
Query: 569 HPGDNAVVVTGWKQGSGFTNTVRVMLV 595
GD +VVTGW+ GSG+TN +RV+ +
Sbjct: 547 RVGDLVIVVTGWRPGSGYTNIMRVLSI 573
>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 744
Score = 504 bits (1242), Expect = e-141
Identities = 249/446 (55%), Positives = 308/446 (69%), Gaps = 4/446 (0%)
Query: 134 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 193
M V RMNFSHGSHEYH +TI+ R+A Y + G P +LAIALDTKGPEIRTG L GG
Sbjct: 1 MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60
Query: 194 S-AEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 252
AE+ELK G+ + L+T + +K N D IYVDY+ + +VKPGNR+F+DDGLI++I +
Sbjct: 61 DRAEIELKTGDKVTLSTKKEMADKSNKDNIYVDYQRLPQLVKPGNRVFVDDGLIALIVKE 120
Query: 253 VSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRN 312
D + C +ENGG LGS KG+NLPG+PVDLP+V+EKDK DL FG EQ VDMIFASFIR+
Sbjct: 121 SKGDEVICQVENGGKLGSHKGINLPGVPVDLPSVTEKDKQDLKFGAEQKVDMIFASFIRD 180
Query: 313 GAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVF 372
AL EIR +LG G IKIISKIENHQG+VN+D+II ESDGIMVARGD+GIEIP E V
Sbjct: 181 ANALKEIRQVLGPAGACIKIISKIENHQGLVNIDDIIRESDGIMVARGDMGIEIPTEDVP 240
Query: 373 LAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAK 432
LAQK+++A+CN+VGKPVICATQM+ESM KPRPTRAE SDVANAI DG D VMLSGETAK
Sbjct: 241 LAQKSIVAKCNKVGKPVICATQMMESMTNKPRPTRAEASDVANAIFDGCDAVMLSGETAK 300
Query: 433 GDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK-PPIDPXXXXXXXXXXXXTKCLAS 491
G YPVECV MA IC + EAV+W+ L N L E++ D T A
Sbjct: 301 GKYPVECVQCMARICAKVEAVLWYESLQNSLKREIRTSAADHISAVTTAIAEAATVGQAR 360
Query: 492 AIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDV 551
AIVV + A ++S RP CPI+ +T + A Q L+RG+ P++ +E + +
Sbjct: 361 AIVVASPCSMVAQMVSHMRPPCPIVMLTGNESEAAQSLLFRGIYPLLVEEMVIGSF--NF 418
Query: 552 DNRVQSGLRFGRQRGFVHPGDNAVVV 577
+QSGL+ + + PG VV
Sbjct: 419 RRIMQSGLKLMGKMDILEPGQKGSVV 444
>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
Pyruvate kinase - Neurospora crassa
Length = 527
Score = 503 bits (1241), Expect = e-141
Identities = 257/513 (50%), Positives = 340/513 (66%), Gaps = 13/513 (2%)
Query: 87 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 145
++G ++Q + L+ + + + R + IICTIGP + +V + K+ + G+NV RMNFSHGS
Sbjct: 10 SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69
Query: 146 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 205
+EYH I N R+AEK + G P +AIALDTKGPEIRTG + ++ + G +
Sbjct: 70 YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTKN--DEDIPISAGTIL 122
Query: 206 KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIEN 264
+TT Y+++ + +YVDY NIT V+ PG I++DDG+++ + + V T+ N
Sbjct: 123 NITTDEKYKDECTIEHMYVDYVNITKVIAPGRIIYVDDGVLAFEVLEIVDDKTIKVKARN 182
Query: 265 GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 324
G + SRKGVNLP VDLPA+SEKDK+DL FGV+ VDM+FASFIR G + +IR +LG
Sbjct: 183 NGYISSRKGVNLPNTDVDLPALSEKDKADLRFGVKNKVDMVFASFIRRGQDIKDIREVLG 242
Query: 325 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
E GK I+II+KIEN QG+ N EI+AE+DG+MVARGDLGIEIP +VF AQK +IA CN
Sbjct: 243 EDGKQIQIIAKIENRQGLNNFAEILAETDGVMVARGDLGIEIPAAEVFAAQKKIIAMCNI 302
Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 444
GKPVICATQMLESM+K PRPTRAEISDV NA+ DGADCVMLSGETAKG YP E V M+
Sbjct: 303 AGKPVICATQMLESMIKNPRPTRAEISDVGNAVTDGADCVMLSGETAKGAYPTEAVREMS 362
Query: 445 NICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAH 504
+AE I + F +L S K P+ A+AI+V++TSG+SA
Sbjct: 363 EAVLKAENTIPYVSHFEELCSLAKRPVSIVESCAMASVRASLDLNAAAILVLSTSGESAR 422
Query: 505 LLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQE--PTAS--DWLKDVDNRVQSGLR 560
L+SKYRP CPII +TR+ +R HLYRGV P ++ E P S +W +DVD R++ GL
Sbjct: 423 LISKYRPVCPIIMITRNDSASRYAHLYRGVYPFLFPESKPDFSKVNWQEDVDRRIKWGLS 482
Query: 561 FGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVM 593
G ++ G+ VVV GWK G G TNT R++
Sbjct: 483 HGIGLKVLNEGETVVVVQGWKGGMGNTNTFRIV 515
>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
Pyruvate kinase - Leishmania mexicana
Length = 499
Score = 500 bits (1234), Expect = e-140
Identities = 254/509 (49%), Positives = 343/509 (67%), Gaps = 13/509 (2%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
SQL H L I + R + IICTIGP++++V L+ ++++GM+VARMNFSHGSHEYH
Sbjct: 2 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 209
TI N R+A +A+LG ++AIALDTKGPEIRTG GG + +++G T +TT
Sbjct: 62 QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGGDAV---MERGATCYVTT 112
Query: 210 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGML 268
+ +KG D Y+DY+N++ VV+PGN I+IDDG++ + QS + TL CT+ N +
Sbjct: 113 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 172
Query: 269 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK 328
R+GVNLPG VDLPAVS KD+ DL FGVEQGVDMIFASFIR+ + ++R LG KG+
Sbjct: 173 SDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGR 232
Query: 329 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
+I II KIENHQG+ N+D II ESDGIMVARGDLG+EIP EKV +AQK +I++CN GKP
Sbjct: 233 DIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKP 292
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
VICATQMLESM PRPTRAE+SDVANA+ +GADCVMLSGETAKG YP E V MA IC
Sbjct: 293 VICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICL 352
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
EA++ + FN + P+ ++ A A+VV++ +G A L++K
Sbjct: 353 EAQSALNEYVFFNSIKKLQHIPMSADEAVCGSAVNSVSETKAKAMVVLSNTGAGARLVAK 412
Query: 509 YRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQ-EPTASDWLKDVDNRVQSGLRFGRQRGF 567
YRP CPI+ VT QT RQ+++ +GV + + + D + ++RV +G+ F + +G+
Sbjct: 413 YRPNCPIVCVTTRLQTCRQLNITQGVESVFFDADKLGHD--EGKEHRVAAGVEFAKSKGY 470
Query: 568 VHPGDNAVVVTGWKQGSGFTNTVRVMLVQ 596
V GD VV+ + G+ N R++LV+
Sbjct: 471 VQTGDYCVVIHADHKVKGYANQTRILLVE 499
>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 554
Score = 491 bits (1212), Expect = e-137
Identities = 236/512 (46%), Positives = 342/512 (66%), Gaps = 4/512 (0%)
Query: 82 KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 141
K + +QL H+C LD+ ++S+ RL +I TI +SRN + M+ G+N+ R+NF
Sbjct: 6 KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65
Query: 142 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 201
SH SHE H++TI EA + + G ++AIA DT+GP+IRTGLL+G +V L+
Sbjct: 66 SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121
Query: 202 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 261
G+ ++L+ + D +KGN + +YVDY NI N+ K G+R+FIDDG + + V D L C
Sbjct: 122 GDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCE 181
Query: 262 IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRG 321
+ +GG L + V LP I +DLPAVSEKD D+ F ++ VD +FAS +R+ + E+R
Sbjct: 182 VIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRT 241
Query: 322 ILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR 381
+LGEKGK+IKII+K+++ + EI+ +DG++++R DLG +IP EK+F+ QK+++ +
Sbjct: 242 VLGEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQ 301
Query: 382 CNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVH 441
CN+VGKPVI A+ +LESM P PTRAE D+ANAI+DGADC+MLS E A G +P E V
Sbjct: 302 CNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVA 361
Query: 442 TMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGK 501
T +C+EAE V+W R LF+DLVSEV+ +D + A+ I+V+TTSG+
Sbjct: 362 TCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVLTTSGR 421
Query: 502 SAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRF 561
SA L+SK+RPRCPI+A+TR +TAR V+L+RGVLPI+Y ++D+ DVD RVQ +
Sbjct: 422 SATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFAMTS 481
Query: 562 GRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVM 593
++ G + GD V+V+ WK G GFTN VRV+
Sbjct: 482 AKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV 513
>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 506
Score = 466 bits (1149), Expect = e-130
Identities = 237/507 (46%), Positives = 313/507 (61%), Gaps = 9/507 (1%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
S+LQ + L I + +R + II TIGP + + + + + G+N+ R+NFSHGS+E+H
Sbjct: 4 SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 209
I N ++E+ + G P LAIALDTKGPEIRTG ++ + + TT
Sbjct: 63 QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTGRTLN--DQDLYIPVDHQMIFTT 115
Query: 210 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 268
+ + N +Y+DY N+T V+ PG I++DDG++S + Q + L N G +
Sbjct: 116 DASFANTSNDKIMYIDYANLTKVIVPGRFIYVDDGILSFKVLQIIDESNLRVQAVNSGYI 175
Query: 269 GSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK 328
S KGVNLP VDLP +S KD DL FGV G+ ++FASFIR + IR LG +G+
Sbjct: 176 ASHKGVNLPNTDVDLPPLSAKDMKDLQFGVRNGIHIVFASFIRTSEDVLSIRKALGSEGQ 235
Query: 329 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
+IKIISKIEN QG+ N DEI+ +DG+M+ARGDLGIEI +V QK +IA+CN GKP
Sbjct: 236 DIKIISKIENQQGLDNFDEILEVTDGVMIARGDLGIEILAPEVLAIQKKLIAKCNLAGKP 295
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
VICATQML+SM PRPTRAE+SDV NA+LDGADCVMLSGETAKGDYPV V+ MA
Sbjct: 296 VICATQMLDSMTHNPRPTRAEVSDVGNAVLDGADCVMLSGETAKGDYPVNAVNIMAATAL 355
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
AE+ I H L++DL P + AIVV++T+G +A LLSK
Sbjct: 356 IAESTIAHLALYDDLRDATPKPTSTTETVAAAATAAILEQDGKAIVVLSTTGNTARLLSK 415
Query: 509 YRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFV 568
YRP CPII VTRH +TAR HLYRGV P +Y+ DW +DV R++ G+ R G V
Sbjct: 416 YRPSCPIILVTRHARTARIAHLYRGVFPFLYEPKRLDDWGEDVHRRLKFGVEMARSFGMV 475
Query: 569 HPGDNAVVVTGWKQGSGFTNTVRVMLV 595
GD V + G+K G G +NT+R+ V
Sbjct: 476 DNGDTVVSIQGFKGGVGHSNTLRISTV 502
>UniRef50_UPI0000E481DE Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 461
Score = 440 bits (1083), Expect = e-122
Identities = 207/343 (60%), Positives = 253/343 (73%), Gaps = 3/343 (0%)
Query: 254 SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNG 313
SAD L C I NGGMLGSRKGVNLP VDLPA+SEKDK DL FG+E GV+M+FASFIR
Sbjct: 117 SADYLDCKIINGGMLGSRKGVNLPNAEVDLPALSEKDKGDLRFGLEHGVEMVFASFIRKA 176
Query: 314 AALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFL 373
+H++R +LGE+G +IKIISKIEN +G+ DEI+ SDGIMVARGDLGIEIPPEKVFL
Sbjct: 177 TDVHQVREVLGEQGAHIKIISKIENQEGVAKFDEILEASDGIMVARGDLGIEIPPEKVFL 236
Query: 374 AQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKG 433
AQK MI+RCN++GK VICATQMLESMV PRPTRAE SDVANA+LDGADCVMLSGETAKG
Sbjct: 237 AQKMMISRCNKIGKSVICATQMLESMVNNPRPTRAETSDVANAVLDGADCVMLSGETAKG 296
Query: 434 DYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAI 493
YPVE V M I +EAEA ++HRQ F +L EV P KCLA AI
Sbjct: 297 KYPVEAVSMMHRISREAEAAVFHRQQFEELTREVDMPTSAGLTVAIAAVEASYKCLAGAI 356
Query: 494 VVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTAS---DWLKD 550
+V+T +G+SAH++S++RP PI+AVTR ARQ+HL+RG P++Y P +W +D
Sbjct: 357 IVLTKTGRSAHMISRFRPLAPILAVTRDQVIARQIHLHRGCFPLLYPYPVEEKDRNWSED 416
Query: 551 VDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVM 593
+DNRV+ + G+ R F +VVTGW+ G+GFTNT+R++
Sbjct: 417 IDNRVKFAVEIGKGRKFFEDNTPVIVVTGWRSGAGFTNTMRII 459
>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
organisms|Rep: Pyruvate kinase - Eimeria tenella
Length = 531
Score = 433 bits (1067), Expect = e-120
Identities = 221/487 (45%), Positives = 313/487 (64%), Gaps = 17/487 (3%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CT+GP+ +V + ++++ GMNV R+NFSHG HE H ++N +EA K K
Sbjct: 60 IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+A+ LDTKGPEIRTG+LEG +EL G+ +K+ T DY GN I Y+ + +
Sbjct: 115 RVALLLDTKGPEIRTGMLEG--DKPIELHAGDMLKIVT--DYSFVGNKSCIACSYEKLPS 170
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VKPGN I I DG +S+ D + + N ++G++K +NLPG+ VDLP + EKDK
Sbjct: 171 SVKPGNTILIADGSLSVEVVECGKDYVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDK 230
Query: 292 SDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 350
+D+L FG+ G + I ASF+++ + IR ILG KG+NIKII KIEN +G++N DEI+
Sbjct: 231 NDILNFGIPMGCNFIAASFVQSADDVRYIRSILGTKGRNIKIIPKIENVEGLLNFDEILQ 290
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
E+DGIM+ARGDLG+EIPPEKVFLAQK MI++CN GKPVI ATQMLESM K PRPTRAE
Sbjct: 291 EADGIMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMTKNPRPTRAEA 350
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
+DVANA+LDG DCVMLSGETA G +PV+ V M+ +C EAE I ++Q+F P
Sbjct: 351 ADVANAVLDGTDCVMLSGETANGSFPVQAVTVMSRVCFEAEGCIDYQQVFRATCQATMTP 410
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
ID AS I+ +T +G++A L++KYRP PI+A++ +T +Q+ +
Sbjct: 411 IDTQEAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALSASEETIKQLQV 470
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFTNT 589
RGV + PT + D +++ L ++ V GD+ V V G K+ +G++N
Sbjct: 471 IRGV--TTFLVPT----FQGTDQLIRNALSAAKELQLVSEGDSIVAVHGIKEEVAGWSNL 524
Query: 590 VRVMLVQ 596
++V++V+
Sbjct: 525 LKVLVVE 531
>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
Glycine max (Soybean)
Length = 511
Score = 423 bits (1041), Expect = e-117
Identities = 220/482 (45%), Positives = 304/482 (63%), Gaps = 26/482 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CT+GPASR+V + EK++ GMNVAR NFSHG+H+YH ET+ N + A + +
Sbjct: 25 IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLKTAMHN------TGI 78
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
A+ LDTKGPEIRTG L+ G ++LK+G+ + +TT DY KG+ + I + YK +
Sbjct: 79 LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITT--DYDIKGDPEMISMSYKKLPV 134
Query: 232 VVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
+KPGN I DG I++ S D T+ C EN LG RK VNLPG+ VDLP ++EK
Sbjct: 135 HLKPGNTILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEK 194
Query: 290 DKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
DK D+L +GV +DMI SF+R G+ L +R +LG KNI+++SK+EN +G++N DEI
Sbjct: 195 DKEDILGWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQLMSKVENQEGVLNFDEI 254
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
+ E+D MVARGDLG+EIP EK+FLAQK MI +CN VGKPV+ ATQMLESM+K PRPTRA
Sbjct: 255 LRETDAFMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRA 314
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
E +DVANA+LDG DCVMLSGE+A G YP V MA IC EAE+ + + +F +++
Sbjct: 315 EATDVANAVLDGTDCVMLSGESAAGAYPELAVKIMARICIEAESSLDYGAIFKEMIRSTP 374
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAV---------- 518
P+ P K A IVV+T G +A L++KYRP PI++V
Sbjct: 375 LPMSPLESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVVVPVLSTDSF 434
Query: 519 --TRHPQT-ARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAV 575
T +T AR +YRG++PI+ + + + + +++ L+ +R PGD V
Sbjct: 435 DWTCSDETPARHSLIYRGLIPILGEGSAKATDAESTEVILEAALKSATERALCKPGDAVV 494
Query: 576 VV 577
+
Sbjct: 495 AL 496
>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 510
Score = 405 bits (997), Expect = e-111
Identities = 222/486 (45%), Positives = 298/486 (61%), Gaps = 30/486 (6%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A + +
Sbjct: 20 IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
A+ LDTKGPEIRTG L+ G ++L +G+ I T S DY +G+++ I + YK +
Sbjct: 74 LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQEI--TISIDYMIEGDSNVISMSYKKLAE 129
Query: 232 VVKPGNRIFIDDGLISIICQSV--SADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
VKPG+ I DG IS+ S S + C EN +LG RK VNLPGI VDLP ++EK
Sbjct: 130 DVKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTEK 189
Query: 290 DKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
DK D++ +GV +D+I SF+R G+ L E+R +LGE KNI ++SK+EN +G++N ++I
Sbjct: 190 DKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRRLLGEHSKNIMLMSKVENQEGVMNCEKI 249
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
+ SD MVARGDLG+EIP EK+FLAQKTMI N +GKPV+ ATQMLESM PRPTRA
Sbjct: 250 LENSDAFMVARGDLGMEIPIEKMFLAQKTMIKMANALGKPVVTATQMLESMTVSPRPTRA 309
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
E +DVANA+LDG DCVMLSGETA G +P V TM+ ICKEAE I + L + V
Sbjct: 310 EATDVANAVLDGTDCVMLSGETAAGAHPEAAVLTMSRICKEAEDFIDYDILHKKTLGMVS 369
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAV---------- 518
P+ P ASAIVV+T G +A L++KYRP PI++V
Sbjct: 370 LPLSPIESLAASVVSTAQSVFASAIVVLTKGGYTAELVAKYRPSVPILSVIVPEIAQGND 429
Query: 519 ------TRHPQTARQVHLYRGVLPIVYQEPTASDWLKD-VDNRVQSGLRFGRQRGFVHPG 571
AR+ +YR ++P+V +A D KD + + + F + +G G
Sbjct: 430 MEMSCSDSVAHAARRGLIYRRIIPVVATGSSARDSNKDATEEMINLAIGFAKTKGICKNG 489
Query: 572 DNAVVV 577
D+ V +
Sbjct: 490 DSIVAL 495
>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
organisms|Rep: Pyruvate kinase - Vibrio cholerae
Length = 470
Score = 396 bits (974), Expect = e-108
Identities = 228/482 (47%), Positives = 289/482 (59%), Gaps = 21/482 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGP + +V L +++ GMNV R+NFSHG + H I N R+ + +L
Sbjct: 6 IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKVMEVTGKQL---- 61
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI LDTKGPEIRT LE G +V+L G+ TT D + GN + + V Y
Sbjct: 62 --AILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTT--DTKVVGNKERVAVTYSGFAK 115
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ GNRI +DDGLI + + + + C + N G LG KGVNLPG+ V+LPA+SEKDK
Sbjct: 116 DLNVGNRILVDDGLIEMEVLATTDTEVKCKVLNNGALGENKGVNLPGVSVNLPALSEKDK 175
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDEIIA 350
+DL FG EQGVD + ASFIR G+ + EIR +L G +NI+IISKIEN +G+ N DEI+
Sbjct: 176 NDLKFGCEQGVDFVAASFIRKGSDVKEIREVLASHGGQNIQIISKIENQEGLDNFDEILE 235
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
SDGIMVARGDLG+EIP E+V AQK MI +CNR K VI ATQML+SM+K PRPTRAE
Sbjct: 236 LSDGIMVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEA 295
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
DVANAI+DG D VMLSGETAKG YPVE V MA I + + V+ +L + L S P
Sbjct: 296 GDVANAIMDGTDAVMLSGETAKGKYPVEAVKIMAQIAERTDPVL-KAELGSRLDS---PR 351
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+ K A I+V T +GKSA + KY P IIAVT + +TA Q+ L
Sbjct: 352 LRITEAVCKGAVDTAEKLAAPLIIVATEAGKSARSVRKYFPTANIIAVTTNKKTAAQLVL 411
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTV 590
+GV P+V D + + D G Q G GD V+V+G SG TNT
Sbjct: 412 SKGVTPVVV------DAIDNTDAFYHLGKEIALQSGLGKKGDIVVMVSGALVASGTTNTA 465
Query: 591 RV 592
V
Sbjct: 466 SV 467
>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
Pyruvate kinase I - Salmonella typhimurium
Length = 470
Score = 395 bits (972), Expect = e-108
Identities = 224/482 (46%), Positives = 292/482 (60%), Gaps = 21/482 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGP + + +L KM++ GMNV R+NFSHG + H + I+N R +K G
Sbjct: 6 IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNV----MSKTGK-- 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI LDTKGPEIRT LEGG +V LK G+T TT D GN + + V Y+ T+
Sbjct: 60 KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT--DKSVVGNNEIVAVTYEGFTS 115
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ GN + +DDGLI + ++ + + C + N G LG KGVNLPG+ + LPA++EKDK
Sbjct: 116 DLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDK 175
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGIL-GEKGKNIKIISKIENHQGMVNLDEIIA 350
DL+FG EQGVD + ASFIR + + EIR L G+NI+IISKIEN +G+ N DEI+
Sbjct: 176 QDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQIISKIENQEGLNNFDEILE 235
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
SDGIMVARGDLG+EIP E+V AQK MI +C R K VI ATQML+SM+K PRPTRAE
Sbjct: 236 ASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEA 295
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
DVANAILDG D VMLSGE+AKG YP+E V MA IC+ + V+ R +N+ +++
Sbjct: 296 GDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLDYNNDSRKLR-- 353
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
K A IVV T GKSA + KY P I+A+T + TARQ+ L
Sbjct: 354 --ITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFPDATILALTTNEVTARQLVL 411
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTV 590
+GV+ + +E + D+ + G Q G GD V+V+G SG TNT
Sbjct: 412 SKGVVSQLVKE------INSTDDFYRLGKDVALQSGLAQKGDVVVMVSGALVPSGTTNTA 465
Query: 591 RV 592
V
Sbjct: 466 SV 467
>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
Pyruvate kinase - Bacillus subtilis
Length = 585
Score = 393 bits (968), Expect = e-108
Identities = 223/492 (45%), Positives = 307/492 (62%), Gaps = 23/492 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG E H I+N REA K K
Sbjct: 1 MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG ++ I LDTKGPEIRT +E GG +EL+ G+ +L S D + G D I V Y
Sbjct: 57 LGK--NVGILLDTKGPEIRTHTMENGG---IELETGK--ELIISMD-EVVGTTDKISVTY 108
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLP 284
+ + + V+ G+ I +DDGLI + V A + + N G L ++KGVN+PG+ V+LP
Sbjct: 109 EGLVHDVEQGSTILLDDGLIGLEVLDVDAAKREIKTKVLNNGTLKNKKGVNVPGVSVNLP 168
Query: 285 AVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-KGKNIKIISKIENHQGMV 343
++EKD D++FG+EQGVD I SFIR + EIR +L E ++I+II KIEN +G+
Sbjct: 169 GITEKDARDIVFGIEQGVDFIAPSFIRRSTDVLEIRELLEEHNAQDIQIIPKIENQEGVD 228
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
N+D I+ SDG+MVARGDLG+EIP E+V L QK +I +CN +GKPVI ATQML+SM + P
Sbjct: 229 NIDAILEVSDGLMVARGDLGVEIPAEEVPLVQKELIKKCNALGKPVITATQMLDSMQRNP 288
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
RPTRAE SDVANAI DG D +MLSGETA G YPVE V TM NI +E + ++++ +
Sbjct: 289 RPTRAEASDVANAIFDGTDAIMLSGETAAGSYPVEAVQTMHNIASRSEEALNYKEILSKR 348
Query: 464 VSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
+V I A+AIV T SG +A +++KYRP+ PI+AVT +
Sbjct: 349 RDQVGMTITDAIGQSVAHTAINLN--AAAIVTPTESGHTARMIAKYRPQAPIVAVTVNDS 406
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG 583
+R++ L GV Q +++D + +++ VQ L G V GD V+ G
Sbjct: 407 ISRKLALVSGVFAESGQNASSTDEM--LEDAVQKSL----NSGIVKHGDLIVITAGTVGE 460
Query: 584 SGFTNTVRVMLV 595
SG TN ++V V
Sbjct: 461 SGTTNLMKVHTV 472
>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
annulata
Length = 513
Score = 380 bits (935), Expect = e-104
Identities = 206/486 (42%), Positives = 292/486 (60%), Gaps = 17/486 (3%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CT+GPA NV + +M+++GMN+ R NFSHG+HE H +T+ +EA KS
Sbjct: 42 IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
++ + LDTKGPEIRTG L+ + L++G T+K+TT DY +G+ I YK +
Sbjct: 97 NIGLMLDTKGPEIRTGFLKN--HTPITLEEGSTLKITT--DYTIEGDETIISCSYKKLPQ 152
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VK GN I I DG +S +V D + + N +G K +NLPG+ V+LP ++E DK
Sbjct: 153 SVKVGNIILIADGSLSCEVLAVFDDYIEVKVLNNAKIGEYKNMNLPGVKVELPVLTESDK 212
Query: 292 SDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 350
+L FG+ +D I SF + + +R +LGEKGK+IKII KIEN +G+ N DEI+
Sbjct: 213 DYILNFGIPNQMDFIALSFTQTAEEVKYVRELLGEKGKHIKIIPKIENIEGLANYDEILE 272
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
SDGIMVARGDLG+E+P EKV LAQK MI R N GKP+I ATQMLESMV PRPTRAE
Sbjct: 273 ASDGIMVARGDLGMEMPIEKVCLAQKMMIKRANMCGKPIITATQMLESMVNNPRPTRAES 332
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
+DV NA+LDG+DCVMLSGETA G +PVECV MA +C EAE + R L + +
Sbjct: 333 ADVINAVLDGSDCVMLSGETAGGRFPVECVKIMAKLCFEAENCLSTRDLMAESLLLNSSQ 392
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
A I+V T +G+++ L+SKYRPRC I++++ + + +
Sbjct: 393 FTVQESIARSAVFLSIDIEAKMILVFTQTGRASRLVSKYRPRCLILSLSEDIHVVKSLSI 452
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFTNT 589
R V+ ++ D L+D D V+ + + R + D VVV G ++ +G ++
Sbjct: 453 SRAVISVLV------DSLEDTDRNVEHAINHAKLRDMLRKDDLIVVVHGARENVAGSSDL 506
Query: 590 VRVMLV 595
++V+ +
Sbjct: 507 IKVVKI 512
>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
Pyruvate kinase - Clostridium phytofermentans ISDg
Length = 580
Score = 377 bits (928), Expect = e-103
Identities = 213/491 (43%), Positives = 293/491 (59%), Gaps = 22/491 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CT+GPA+ + AVL ++M GM+VAR NFSHG +E H R SA+
Sbjct: 1 MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRRL----SAE 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
L P +A LDTKGPEIR G E G ++ELKKG+ LTT+ G+ + + Y
Sbjct: 57 LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTNDIV---GDETQVSITY 108
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
KN+ +K G +I IDDGLI + +++ + C + NGGM+ + KGVN+PG+ + +P +
Sbjct: 109 KNLIRDIKNGVKILIDDGLIELKVFNITDTDIICEVLNGGMISNHKGVNVPGVELSMPFI 168
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN-IKIISKIENHQGMVNL 345
S++D D++FG+ QG D I ASF R + +IR IL E N + II+KIEN QG+ N+
Sbjct: 169 SKRDYEDIVFGIGQGFDFIAASFTRCADDIIQIRKILNEYNCNTVNIIAKIENLQGVNNI 228
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
DEII SDGIMVARGD+G+EIP E+V + QK +I + K VI ATQML+SM+K PRP
Sbjct: 229 DEIIRVSDGIMVARGDMGVEIPLEEVPVIQKMIIKKVYNAEKQVITATQMLDSMMKNPRP 288
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
TRAE +DVANAI DG +MLSGETA G YPVE + TM I K EA I + F S
Sbjct: 289 TRAEATDVANAIYDGTSAIMLSGETAAGLYPVEALRTMVKIAKRTEADIDYTSRFRKRDS 348
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
P D A+AI+ +T SGK+A ++SKYRP IIA T +
Sbjct: 349 LTNP--DVTNAISHATVTTAIDLNAAAIITVTKSGKTARMISKYRPPSSIIACTTYEHIC 406
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-S 584
RQ++L GV+P++ +E D + + + + GFV G+ AV+ G G S
Sbjct: 407 RQMNLSWGVVPLLIEEEV------DANTLFEHAVEAAEKAGFVKSGELAVITAGVPLGIS 460
Query: 585 GFTNTVRVMLV 595
G TN ++V +V
Sbjct: 461 GTTNLIKVQVV 471
>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
Oligohymenophorea|Rep: Pyruvate kinase family protein -
Tetrahymena thermophila SB210
Length = 505
Score = 375 bits (923), Expect = e-102
Identities = 197/474 (41%), Positives = 286/474 (60%), Gaps = 10/474 (2%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGP+ + L +++E GMNVAR+NFSHG H H ET+R +EA K+
Sbjct: 22 RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKARKN-- 79
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
A+ LDTKGPEIRTGL++ + L G+ +++TT DY G+ + YK
Sbjct: 80 ---IQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT--DYSVLGDEKVLACSYK 134
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ VK G ++ I DG + I + + D++ ++N +G +K +NLPG VDLP V+
Sbjct: 135 SLPKSVKVGGQVLIADGTLVCIVKEIKQDSIIVNVQNTCSIGEKKNMNLPGAIVDLPTVT 194
Query: 288 EKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
EKD+ D++ FG++ G+D I SF R + +R ILG +G++IKII+KIEN +G+ N +
Sbjct: 195 EKDEDDIVNFGLKHGIDCIALSFARKAEDIEYVRDILGPQGEHIKIIAKIENQEGLHNYE 254
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
+I+ +DGIMVARGDLG+EIPP+KVF+AQK MI + GKP+I ATQM+ESM+K PRPT
Sbjct: 255 QILDAADGIMVARGDLGMEIPPQKVFVAQKWMIRKALEKGKPIITATQMMESMIKNPRPT 314
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVANA+LDG D VMLSGETA G +P++ V TMA IC EAE +RQ F +
Sbjct: 315 RAEASDVANAVLDGTDAVMLSGETANGSFPIQAVQTMAYICSEAELCYDNRQTFWQRTNN 374
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
K + + + I+V TT+G A +SKYRP I V+ T +
Sbjct: 375 -KKKVSAVESMAISAVQMSFEIESPVIIVFTTNGDMARYVSKYRPSAQIFVVSTENGTIK 433
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNR-VQSGLRFGRQRGFVHPGDNAVVVTG 579
+ GV + ++ + N+ + + +++GF+ G NA+V+ G
Sbjct: 434 GLCTTFGVRCLRVPSFQGENYYFNCINKLIDYAVDAAKEQGFIKSGQNAIVILG 487
>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
Pyruvate kinase - Phaeodactylum tricornutum
Length = 543
Score = 369 bits (908), Expect = e-100
Identities = 217/498 (43%), Positives = 293/498 (58%), Gaps = 23/498 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGPA NV LE ++E+GMNVAR NFSHG H H + R+A ++
Sbjct: 31 RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
++AI LDTKGPEIRTG G S ++EL KGETI LT SDY+ KG+ + Y
Sbjct: 89 ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLT--SDYKFKGDQHKLACSYP 141
Query: 228 NITNVVKPGNRIFIDDG--LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
+ V G +I + DG +++++ +A ++C I+N +G RK +NLPG+ VDLP
Sbjct: 142 ALAQSVTQGQQILVADGSLVLTVLQTDEAAGEVSCRIDNNASMGERKNMNLPGVKVDLPT 201
Query: 286 VSEKDKSDLL-FGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMV 343
+EKD D++ FG++ VD I ASF+R + + +R +L E G + IKI KIEN +G+
Sbjct: 202 FTEKDVDDIVNFGIKHKVDFIAASFVRKQSDVANLRQLLAENGGQQIKICCKIENQEGLE 261
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
N D I+ +D IMVARGDLG+EIPP KVFLAQK MI N GKPVI ATQMLESM+ P
Sbjct: 262 NYDAILQATDSIMVARGDLGMEIPPAKVFLAQKMMIREANIAGKPVITATQMLESMINNP 321
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
RPTRAE SDVANA+LDG DCVMLSGETA G Y E V MA C EAE + L++ +
Sbjct: 322 RPTRAECSDVANAVLDGTDCVMLSGETANGPYFEEAVKVMARTCCEAENSRNYNSLYSAV 381
Query: 464 VSEVKP---PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTR 520
S V + P A I+V++ SG +A +SK+RP I+ +T
Sbjct: 382 RSSVMAKYGSVPPEESLASSAVKTAIDVNARLILVLSESGMTAGYVSKFRPGRAIVCLTP 441
Query: 521 HPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRV-QSGLRFGRQRGFVHPGDNAVVVTG 579
ARQ G+L V+ D L + + + ++G+ + G GD VVV+G
Sbjct: 442 SDAVARQT---GGILKGVHS--YVVDNLDNTEELIAETGVE-AVKAGIASVGDLMVVVSG 495
Query: 580 WKQGSGFTNTVRVMLVQS 597
G G N VRV ++++
Sbjct: 496 TLYGIGKNNQVRVSVIEA 513
>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
(Water mold)
Length = 517
Score = 364 bits (895), Expect = 4e-99
Identities = 194/488 (39%), Positives = 292/488 (59%), Gaps = 29/488 (5%)
Query: 102 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 161
SK+ ++ I+ T+GP S N +++ G+ + R+NFSH +++ + + R ++
Sbjct: 23 SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82
Query: 162 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 220
++ G F++ A+ LDT+GPEIR G ++ L KG+ I LTT Y+E D
Sbjct: 83 VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQYKEASTKD 139
Query: 221 TIYVDYKNITNVVKPGNRIFIDDGLISIICQS--VSADTLTCTIENGGMLGSRKGVNLPG 278
+YV Y+ + VK G+ + +DDGLIS+ +S V++ + C IEN +LGSRKGVNLPG
Sbjct: 140 MLYVTYEQLPATVKVGDTVLLDDGLISLTVKSIDVASGQVRCLIENSEVLGSRKGVNLPG 199
Query: 279 IPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNI-------- 330
+ VDLPA++ KDK D+ FGVE +D I SF+R +++++ +
Sbjct: 200 LVVDLPALTAKDKQDVEFGVEHDMDFIAVSFVRKPEDVNDVKDFVNSVMPKYWPAGHPAP 259
Query: 331 KIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVI 390
IISKIEN++G+ N D I+ SDGIMVARGDLG+EIP ++V QK M+++CN GKPVI
Sbjct: 260 LIISKIENYEGVSNFDRILEVSDGIMVARGDLGVEIPMQEVLTCQKDMVSKCNAAGKPVI 319
Query: 391 CATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEA 450
ATQMLESM++ PRPTRAEI DV NA+LDGAD VMLSGE A+G +PVE V TM ++ KEA
Sbjct: 320 VATQMLESMIRNPRPTRAEILDVGNAVLDGADAVMLSGEVAQGKWPVESVKTMMSVIKEA 379
Query: 451 EAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYR 510
+A + Q + +S+ + A+ IVV+T SG+ A L+SK++
Sbjct: 380 DAYVKREQYKKEALSQKE-------AVACAVATTAKSLHAAMIVVMTASGEVARLVSKHK 432
Query: 511 PRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHP 570
P P++ T + RQ+ ++RG+ PIV P + +Q + ++ G++H
Sbjct: 433 PSVPVMCYTTSQKVGRQLQIHRGLYPIVAPTPCKMN--------LQEAISTAKKLGWLHN 484
Query: 571 GDNAVVVT 578
GD V+++
Sbjct: 485 GDQVVMLS 492
>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pyruvate kinase -
Collinsella aerofaciens ATCC 25986
Length = 486
Score = 362 bits (891), Expect = 1e-98
Identities = 204/473 (43%), Positives = 286/473 (60%), Gaps = 22/473 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CT+GPA + + +M++ GMNVAR NFSHGS++ H I R K +LG P
Sbjct: 7 IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT---TSSDYQEKGNADTIYVDYKN 228
+ I LDTKGPE+RTGLL G +V +K G+ I +T TS D+ G A+ I +DY
Sbjct: 62 -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDFH--GTAEHISLDYLA 116
Query: 229 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 288
+ + V+ G+ I IDDGL+++ +SV +TC ++N G++G RKGVN+P + + LPA++E
Sbjct: 117 LPSEVEKGSLILIDDGLVALEVESVDGQDMTCVVKNDGLIGERKGVNMPNVNISLPAITE 176
Query: 289 KDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDE 347
+D+ D+LFG+ + +D I ASFIR+G ++ IR + E G +++ I KIE G+ N DE
Sbjct: 177 RDRQDILFGLTENIDYIAASFIRDGESVRGIRELCRENGGEHVTIFPKIECALGVENFDE 236
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ SDGIMVARGDLGIEI PE V QK +IA+CN KPVI ATQML+SM + PRPTR
Sbjct: 237 ILEASDGIMVARGDLGIEIKPELVPHIQKEIIAKCNAAYKPVITATQMLDSMQQNPRPTR 296
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVI-WHRQLFNDLVSE 466
AE++DVANAI DG D VMLSGE+A G YPVE V A+I E E + H L ++ ++
Sbjct: 297 AEVADVANAIYDGTDAVMLSGESAAGKYPVEAVKMQASIALETEKYLPAHAPL--EVPAD 354
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
T A I V TT+G++A L+S +RP PI A +RH +
Sbjct: 355 AHGTRVVNNVVGMSAVNMATTVGAKCITVPTTTGRTARLISHFRPNMPICAFSRHEWAVQ 414
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
Q+ +Y GV+P +Q V+ + + ++ G+V GD V G
Sbjct: 415 QMIMYWGVIP--HQAEITQG---TVNGTIVKAIETAKELGYVKAGDLTVATAG 462
>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
organisms|Rep: Pyruvate kinase - Uncultured methanogenic
archaeon RC-I
Length = 583
Score = 343 bits (843), Expect = 9e-93
Identities = 193/490 (39%), Positives = 279/490 (56%), Gaps = 22/490 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CTIGPA + +LEK+ GMNVAR+N SH HE+ +TI N R ++
Sbjct: 1 MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIRMVSEA---- 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+G P + I +D +GP+IR G L+ LK G T LTT G++ + V +
Sbjct: 57 IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTTRD---VPGDSQEVNVPF 107
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
K + V G + +DDGLI + +V+ + + GG L S+KG+NLP + +P++
Sbjct: 108 KELPQSVSTGQTLLLDDGLIELKVDAVTETDIRTKVVRGGELKSKKGINLPQSTIRIPSI 167
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+EKD DL FG+E VDMI SF+R + ++R + + +I IISKIE H+ + N+D
Sbjct: 168 TEKDVRDLEFGIEHEVDMIAMSFVRKPQDVLDLRKKIEDNDSDIPIISKIEKHEAVKNID 227
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
II DG+MVARGDLGIEIP +V + QK +I++C G PVI ATQML+SM++ P PT
Sbjct: 228 GIIDVVDGVMVARGDLGIEIPMAEVPIVQKMIISKCIARGIPVITATQMLDSMIRNPIPT 287
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE +DVANA+ DG D +MLSGETA G+YPV+ V TMA I K E +++
Sbjct: 288 RAEATDVANAVFDGTDALMLSGETAFGEYPVKAVETMARIAKYTEESTYYKHAI--AAKA 345
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
KP + A AI+ T +G SA +SKYRP+ PI+AVT P+
Sbjct: 346 PKPSLSMTDAVAQSTTESARVLKAQAIITATQTGYSARKVSKYRPQLPILAVTNDPKVVN 405
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SG 585
++ L VLP++ P ++D +Q + Q+G+V GD V+ G G G
Sbjct: 406 RLTLSWAVLPLLIGSP------GNLDELIQDSVDACLQKGYVKNGDLVVITAGVMTGIPG 459
Query: 586 FTNTVRVMLV 595
TN +++ +V
Sbjct: 460 GTNIMKIHVV 469
>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
Length = 591
Score = 342 bits (841), Expect = 2e-92
Identities = 195/495 (39%), Positives = 294/495 (59%), Gaps = 29/495 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ TIGPA+++ VL ++++ G R+NFSHG H YH ++IR R+ + +L
Sbjct: 8 RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQI----AFEL 63
Query: 168 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VD 225
P + I D +GP+IR G L GS V+LK G+ LT+ + +TI +
Sbjct: 64 NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTS----RPVECTETISSIS 115
Query: 226 YKNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDL 283
Y+ + + V G RI +DDG + ++ + V A L C + GG L S KGVN PG+ + +
Sbjct: 116 YEYLADEVPSGARILLDDGKLEMLVEEVDTVARDLHCRVIVGGTLSSNKGVNFPGVCLSV 175
Query: 284 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMV 343
A+++KDK DL+FG++QGVD + SF+RN + EI+G++ GK++ +I+KIE H+ +
Sbjct: 176 KAMTDKDKEDLMFGLDQGVDWVALSFVRNPQDIDEIKGLIAAAGKSVPVIAKIEKHEAIK 235
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
++ ++ + DG+MVARGDLG+E+P E V + QK +IA NR+G PVI ATQML+SMV P
Sbjct: 236 DMQAVLEKCDGVMVARGDLGVELPAEDVPILQKKLIATANRLGIPVITATQMLDSMVNSP 295
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
RPTRAE+SDVANAILDG D VMLS ETA G +PVE V MA I + E ++ N
Sbjct: 296 RPTRAEVSDVANAILDGTDAVMLSNETAIGKFPVEAVAIMAKIAERIE-----QEDINPS 350
Query: 464 VSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
+E P T A+AI+ +T +G +A +SK+RP+ PI+AVT H
Sbjct: 351 QAEASRTSIPNAISSAVSQIAET-LNAAAIMSLTKTGSTARHVSKFRPKTPILAVTPHVD 409
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG 583
+RQ+ L GV P++ + L Q+ + ++ F+ GD V+ G QG
Sbjct: 410 VSRQLQLVWGVKPLLVLD------LPSTSQTFQAAINVAQENHFLRDGDLVVMTAGTLQG 463
Query: 584 -SGFTNTVRVMLVQS 597
+G T+ ++V +V++
Sbjct: 464 VAGSTDLIKVEVVKA 478
>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 486
Score = 338 bits (831), Expect = 2e-91
Identities = 187/497 (37%), Positives = 294/497 (59%), Gaps = 23/497 (4%)
Query: 102 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 161
S+SS R + IICTIGPA+ + +++ + E GMNVAR+N SHG+H++H IRN + K
Sbjct: 3 SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62
Query: 162 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 221
L +P +AI LDT+GPEIRTG L+ ++LK GET E+ +
Sbjct: 63 DV---LKNP--IAILLDTQGPEIRTGDLQVD---HLDLKVGETFTFHIIPG--EESEEQS 112
Query: 222 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 281
++V+YK+I +K G+ + +D+GLI+++ + ++ L C + +GG LGSRK +NLPGI V
Sbjct: 113 VFVNYKDIVKDLKVGDPVTVDNGLINLVVEEINDSALKCKVLDGGRLGSRKHINLPGIRV 172
Query: 282 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQG 341
+LP+++ KD D+LFG+E+ VD I SF+R+ +++++ I+ E + +II+KIE+ +
Sbjct: 173 NLPSITPKDHKDILFGLEEDVDFIALSFVRSVEDINQLKQIIEENDGHAQIIAKIEDQEA 232
Query: 342 MVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVK 401
+ N+ EI+ +DG+MVARGDLG+E+P E++ + Q+ +I C GK VI AT +LESM+
Sbjct: 233 VRNMKEIVEAADGVMVARGDLGVEVPIEELPILQRAIIKECALKGKRVIVATHLLESMIH 292
Query: 402 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFN 461
P PTRAE++DVANAI + AD +MLSGETA G +P+ CV M I + E +
Sbjct: 293 NPSPTRAEVTDVANAIYEEADAIMLSGETAAGKFPIRCVEMMDKIAQRVE-----KTGGV 347
Query: 462 DLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPII-AVTR 520
D V + K P D AI+VIT G +A ++ + P P+I A T
Sbjct: 348 DYVKD-KIPQDKKEQMARAAAKLADSLKCPAIIVITRRGTTALNVAGFHPHYPLIYAFTN 406
Query: 521 HPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGW 580
R++ L RGV+ P D+ KD + ++ + ++ G + GD V+++
Sbjct: 407 MTTVRRKLWLTRGVI------PHRIDFSKDPEKTIRLAIETLKKTGRIEDGDQVVILSDI 460
Query: 581 KQGSGFTNTVRVMLVQS 597
G T+++ V++
Sbjct: 461 IAGEDRVETIQIREVKT 477
>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
psychrophila|Rep: Pyruvate kinase - Desulfotalea
psychrophila
Length = 581
Score = 338 bits (830), Expect = 3e-91
Identities = 190/485 (39%), Positives = 281/485 (57%), Gaps = 22/485 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II T+GP S++V + +++ GMNVAR+N SHG E + I N +EA K
Sbjct: 6 IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKLAEK------ 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI LD +GPEIR +E ++ L GE + +T + E + I +Y +
Sbjct: 60 DTAILLDNRGPEIRVSEME----EDIHLVDGEELVITNRA---ETVSPSRITTNYPQLAG 112
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V+ G+RI +DDG +++ ++ + + + GG+L SRK V LP V+LP++SEKDK
Sbjct: 113 DVQVGSRILLDDGKLALEVLAIEDEEVITKVIAGGILSSRKRVALPDNEVNLPSLSEKDK 172
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
D+ FGVEQ VD I ASF+R + +R I+ + G + +II+KIEN QG+ NLDEI+
Sbjct: 173 EDIAFGVEQDVDFIAASFVRQAGDVWAVRKIIEDNGGDQEIIAKIENRQGVNNLDEILQA 232
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
++GIMVARGDLG+E+P E+V + QK++I NR+GKPVI ATQMLESM+ P PTRAE +
Sbjct: 233 ANGIMVARGDLGVEVPAEEVPIIQKSIIKAANRLGKPVITATQMLESMITCPTPTRAEAN 292
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DV NAI DG D VMLSGETA G YPV+ V + AE + + + + + +P I
Sbjct: 293 DVTNAIFDGTDAVMLSGETAIGKYPVQAVAFLVRCATIAENALDYDHILANGLQNRRPTI 352
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
K A+AI+ T+SG +A ++++YRP+ P+IAV+ P T R + L
Sbjct: 353 TDSISYASCATAADLK--ATAIITATSSGSTARMVARYRPKAPVIAVSPSPSTIRHLQLI 410
Query: 532 RGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFTNTV 590
RGV P++ ++ +D ++ + +H GD ++ G G +G TN +
Sbjct: 411 RGVTPLL------CNFGSSMDEQLDRVIHAATLAELIHNGDLVIITAGMPLGPTGTTNML 464
Query: 591 RVMLV 595
+V V
Sbjct: 465 KVHTV 469
>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
Length = 483
Score = 337 bits (828), Expect = 6e-91
Identities = 195/471 (41%), Positives = 276/471 (58%), Gaps = 28/471 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA +R R E+ ++ +P
Sbjct: 20 IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+L D +GP+IR G L GG E +L++GE + L A + +DY ++
Sbjct: 76 TLL--QDLQGPKIRIGQLPGG---EKQLREGEKVSLVPVEIGDRHPGA--VGIDYPHLAT 128
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
K G RI +DDGL+ + S+ + C + GG+L SRKGVNLPG+ + LP+++ KDK
Sbjct: 129 EAKVGERILLDDGLLEMKVVSIQDPEVICEVVTGGILKSRKGVNLPGLVLTLPSMTTKDK 188
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLDEIIA 350
DL FG+ QG+D + SF+R G +H ++ L E+G ++ +I+KIE Q + NL+EI+A
Sbjct: 189 QDLEFGLSQGIDWVSLSFVRKGEDIHTLKQFLAERGHPDLPVIAKIEKPQAIDNLEEIVA 248
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
S+GIMVARGDLG+E+ PEKV QK +I RCN PVI ATQML+SM++ RPTRAE
Sbjct: 249 VSNGIMVARGDLGVEVNPEKVPRLQKEIIRRCNVRAIPVITATQMLDSMIQNSRPTRAEA 308
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
SDVANAILDG D VMLSGE+A G YPV+ V + I +E E + L N+ PP
Sbjct: 309 SDVANAILDGTDAVMLSGESAVGQYPVKSVQMLRKIAEETEVGL---HLVNN------PP 359
Query: 471 IDPXXXXXXXXXXXXTKCLASA--IVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
I+ + IV TTSG ++ L S RP P+IA T + +
Sbjct: 360 IENTETHALSEALVVIDGILDLKYIVTFTTSGFTSLLASNQRPSVPVIAFTPSEKVYHSL 419
Query: 529 HLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
+L G++P + E D +D+ +Q R R V GD +++ G
Sbjct: 420 NLVWGIIPFLINE--EFDTFEDL---IQQAEVLLRDRKMVEKGDQLLIMAG 465
>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
Length = 491
Score = 333 bits (819), Expect = 7e-90
Identities = 194/487 (39%), Positives = 278/487 (57%), Gaps = 19/487 (3%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPAS + VL++M+ G++VAR+NFSHG HE HA+ + R A S
Sbjct: 4 MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG ++A+ D +GP+IRTG L G V L+ G + + T D + KG+A + Y
Sbjct: 60 LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIAT--DAEVKGDAKLVSTTY 114
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
++ V+PG+R+ +DDGLI + C + GG+L KG+NLPG+ + A+
Sbjct: 115 PHLAEDVRPGDRLLVDDGLIELRVLETDGVRARCQVVEGGVLREHKGINLPGVALRAEAL 174
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
SEKD++D+ FG+ GVD + SF+R+ + R + G+ + +I+KIE + + +D
Sbjct: 175 SEKDRADIAFGLAHGVDAVALSFVRSAEDIRACRDEMERVGRVVPVIAKIEKPEALDAID 234
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
II +DGIM+ARGDLG+EI PE+V L QK + R N GKPV+ ATQMLESM++ PRPT
Sbjct: 235 AIIEAADGIMIARGDLGVEILPERVPLLQKDICRRGNAAGKPVVIATQMLESMIEHPRPT 294
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVANA+ DGAD VMLS E+A G +P+ V M I +EAE D+ S
Sbjct: 295 RAEASDVANAVWDGADAVMLSAESASGRFPLNAVQMMDRIVREAETSPAPSVGIPDVRSR 354
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
P A AI T SG +A LLS +RPR P+IA + R
Sbjct: 355 ---PAAFNLVTAAAACEAADAAGAVAICCFTLSGTTARLLSHFRPRVPVIAFSPDQSIRR 411
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SG 585
++ LY GV+P V + +D + ++ + V G G V PGD V+V G G G
Sbjct: 412 RLALYWGVVPRVLEPVKNADLMAELVSDVLLG------DGVVKPGDRVVLVHGSPLGIPG 465
Query: 586 FTNTVRV 592
TN++R+
Sbjct: 466 QTNSIRL 472
>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
dehalogenans 2CP-C|Rep: Pyruvate kinase -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 489
Score = 333 bits (818), Expect = 9e-90
Identities = 196/490 (40%), Positives = 282/490 (57%), Gaps = 24/490 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPAS VL +++E G++VAR+NFSHG HE HA + R A S
Sbjct: 1 MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG ++A+ D +GP+IRTG L+ G A V+++ G+ + +TT + G+A + Y
Sbjct: 57 LGK--AVAVLQDLQGPKIRTGPLKAG-KAGVQVEAGQELVITTEGELP--GDAHLVSTTY 111
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
++ V+ G+R+ +DDGL+ + + + GG LG KG+NLPG+ + A+
Sbjct: 112 PHLAEDVRAGDRLLVDDGLLEFRVLATDGVRVRTEVVEGGWLGEHKGINLPGVALRAEAL 171
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
SEKD++D+ FG+ GVD + SF+R + R + G+ + II+KIE + + NLD
Sbjct: 172 SEKDRADVAFGISHGVDYVALSFVRTPEDIALCRDEMERAGRVVPIIAKIEKPEAIDNLD 231
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
IIA +DG+MVARGDLG+EI PE+V L QK + ++ N GKPVI ATQML SM++ PRPT
Sbjct: 232 AIIAAADGVMVARGDLGVEILPERVPLLQKEICSKANASGKPVIIATQMLNSMIEHPRPT 291
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVAN I DGAD VMLSGETA G +P+ V M I +EAEA L +
Sbjct: 292 RAEASDVANGIWDGADAVMLSGETASGRFPLAAVQMMDRIVREAEA-----GTPAALHAR 346
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVI---TTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
+ PP P A+ V I T G++A LL+ +RPR PI+A +
Sbjct: 347 IPPPARPAPFNLVTASAACEAAEAAGAVAICCFTLRGETARLLAHFRPRVPIVAFSPDQS 406
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG 583
R++ LY GVLP V + +D + ++ V L + V PGD V+V G G
Sbjct: 407 IRRRLALYWGVLPKVMEPVKNADLMAEI---VSDRL---LEERLVKPGDRVVLVHGSPLG 460
Query: 584 -SGFTNTVRV 592
G TN++R+
Sbjct: 461 LPGQTNSIRL 470
>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
nigroviridis|Rep: Pyruvate kinase - Tetraodon
nigroviridis (Green puffer)
Length = 569
Score = 332 bits (817), Expect = 1e-89
Identities = 156/270 (57%), Positives = 193/270 (71%), Gaps = 1/270 (0%)
Query: 327 GKNIKIISKIENHQGM-VNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV 385
G+ ++ + G + L + + SDGIMVARGDLGIEIP EKVFLAQK MI RCNR
Sbjct: 300 GRLSNLVCNCRRYSGFFLGLMKSMEASDGIMVARGDLGIEIPTEKVFLAQKMMIGRCNRA 359
Query: 386 GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMAN 445
GKP+ CATQMLESM+KKPRPTRAE SDVANA+LDGADC+MLSGETAKGDYP+E V T
Sbjct: 360 GKPITCATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRTQHM 419
Query: 446 ICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHL 505
I +EAEA +HRQLF +L + DP KC ASA+VV+T +G+SAHL
Sbjct: 420 IAREAEAATFHRQLFEELRRHSQLTRDPSEAVAVGAVEASFKCCASALVVLTKTGRSAHL 479
Query: 506 LSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQR 565
+S+YRPR PI+AVTR+ QTARQ HLYRG+ P++Y P W +DVD RV + G+ R
Sbjct: 480 ISRYRPRAPILAVTRNAQTARQAHLYRGIFPVLYTNPPNDVWAEDVDMRVNFAMEMGKAR 539
Query: 566 GFVHPGDNAVVVTGWKQGSGFTNTVRVMLV 595
GF GD +++TGW+ GSG+TNT+RV+LV
Sbjct: 540 GFFKEGDVVIILTGWRPGSGYTNTMRVVLV 569
Score = 325 bits (799), Expect = 2e-87
Identities = 157/258 (60%), Positives = 199/258 (77%), Gaps = 7/258 (2%)
Query: 92 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 151
L+HMC LDIDS + R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE
Sbjct: 25 LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84
Query: 152 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 211
TI+N REA +S+ + IALDTKGPEIRTGL+ G G+AEVELKKG IK+T
Sbjct: 85 TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144
Query: 212 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVS-------ADTLTCTIEN 264
Y EK + + +++DYKNIT VV G++I+IDDGLIS+ + + +D L C IEN
Sbjct: 145 AYVEKCSEEILWLDYKNITKVVDVGSKIYIDDGLISLQVKEIGNSSISSGSDYLMCEIEN 204
Query: 265 GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILG 324
GG LGS+KGVNLPG VDLPAVS+KD DL FGVEQGVDM+FASFIR A +H +R +LG
Sbjct: 205 GGTLGSKKGVNLPGAAVDLPAVSDKDVKDLQFGVEQGVDMVFASFIRKAADVHAVRAVLG 264
Query: 325 EKGKNIKIISKIENHQGM 342
EKGK+IKIISK+ENH+G+
Sbjct: 265 EKGKDIKIISKLENHEGV 282
>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Strongly
similar to pyruvate kinase - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 332 bits (815), Expect = 2e-89
Identities = 192/487 (39%), Positives = 282/487 (57%), Gaps = 22/487 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGPAS + A++E+++ GMNVAR+NFSHG H E I + R + S KL
Sbjct: 5 RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
P +A+ D GP+IR G+L G V LK +T LTT + GN I ++Y
Sbjct: 61 MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTTRNIV---GNERVISINYS 112
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ V G+ + + DG I + + C + GG+L SRKG+N+P + + +++
Sbjct: 113 DLPMNVSIGDTLLLSDGEIEVEVIQKDDRNIHCKVIVGGVLTSRKGINIPARSLPVSSLT 172
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKDK DL FG+EQGVD + SF++ + E+R ++ +KGK I II+KIE H+ + N+++
Sbjct: 173 EKDKKDLEFGIEQGVDYVAMSFVKTAEDITELRDLIQKKGKTIPIIAKIEKHEAVDNIEK 232
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ +D IMVARGDLG+EIP E+V QK +I NR GKPVI ATQML SMV RPTR
Sbjct: 233 IVNTADAIMVARGDLGVEIPLERVPSVQKMIIRLANRYGKPVITATQMLASMVNNYRPTR 292
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL-VSE 466
AE++DVANAILDG+D VMLS E+A G YP + V + I K+ E + F + E
Sbjct: 293 AEVTDVANAILDGSDAVMLSEESAIGRYPADAVLMLTKIAKQIEPDLTQSNTFEKFRIPE 352
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
+ I + + I+ T SG +A +SKYRPR I+AVT T R
Sbjct: 353 NRTTIP--DAISIATCQVANELNMNTIITCTQSGSTARFISKYRPRQKILAVTPSVCTYR 410
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SG 585
++ L GV+PI+ ++ +++ D+ ++ G+ +Q G++ + + G G G
Sbjct: 411 RLALVWGVIPIL------TESMENTDDMMKKGIEAAKQAGYIGENETIAITGGVPVGIPG 464
Query: 586 FTNTVRV 592
TN +RV
Sbjct: 465 STNLLRV 471
>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
sulfurreducens
Length = 480
Score = 331 bits (814), Expect = 3e-89
Identities = 183/427 (42%), Positives = 252/427 (59%), Gaps = 16/427 (3%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + II T+GP S + ++ ++M+ G++V R+NFSHGS++ E I R SA+
Sbjct: 6 RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVIAAIRRL----SAER 61
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G + I D +GP+IRTG +E G + L +G+++ +TT G TIY +
Sbjct: 62 GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITTDEVLGRPGLISTIY---Q 113
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ + VKPG+RI +DDGLI + QSVS T+ CT+ GGML KG+NLPG+ V P++S
Sbjct: 114 SLPHDVKPGSRILLDDGLIELRVQSVSGATVRCTVVQGGMLKDLKGINLPGVKVSAPSLS 173
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD DL F +E GVD I SF+R A + ++ IL E+ + +++KIE + + N
Sbjct: 174 EKDLRDLDFCLEVGVDYIALSFVRTAADVEGLKRILFERDVQVPVVAKIEKPEALRNFKS 233
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ +D +MVARGDLG+EI PEKV L QK +I CN GKPVI ATQMLESM+ PRPTR
Sbjct: 234 ILKVADAVMVARGDLGVEISPEKVPLFQKKIIRACNEAGKPVITATQMLESMISHPRPTR 293
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVANAILDG D VMLSGETA G +P+E V TM + + E D
Sbjct: 294 AETSDVANAILDGTDAVMLSGETASGQFPLEAVRTMDKVALDVERF----AQVEDGSGPR 349
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ + A A+ +T SG +A +S+YRP PI+A T T R+
Sbjct: 350 RHSVSIAEAVAEAACHAAVILKAKAVACMTQSGSTAARISRYRPPLPILAFTGSVDTMRR 409
Query: 528 VHLYRGV 534
+ LY GV
Sbjct: 410 LSLYWGV 416
>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
B - Apis mellifera
Length = 538
Score = 331 bits (813), Expect = 4e-89
Identities = 168/519 (32%), Positives = 299/519 (57%), Gaps = 8/519 (1%)
Query: 81 EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 140
E+ A ++L+H L+I+S RL+ I+ T+G + + + +M G N+ R+N
Sbjct: 12 EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71
Query: 141 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 198
+H + ++H T+++ R+A + + L +A++ +GPEIR G G ++ +
Sbjct: 72 MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131
Query: 199 LKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTL 258
LK+G+ +KL T + G A+ +V Y N+ + + G+RI ID G + + + +
Sbjct: 132 LKEGKMVKLVTQDIAKRAGRANCFWVSYPNLPKICQVGDRILIDRGAVLLQVTCIHEQAI 191
Query: 259 TCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHE 318
TC I GG++ K + L V LP +SEKD + + + D + + +RN L+
Sbjct: 192 TCKIIKGGIVKDGKLIQLLDSLVPLPQISEKDIAHVKWASHLECDFLIMNHVRNEKVLYT 251
Query: 319 IRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTM 378
I+ E +++IISKI + QG+ NLDEI+ +D I++ R + +E+ +K+FL +K +
Sbjct: 252 IKSRFKEM--SMRIISKISSQQGLENLDEILNAADAILLDRKGIEVEVGDKKLFLVEKII 309
Query: 379 IARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE 438
IA+C ++GKP+I + ++ + K +++ +ANA+L+G D ++L + + +
Sbjct: 310 IAKCIKMGKPIILSFEVCDENDK----VNIDMNLIANAVLNGIDAILLKTGSLNVNDTSQ 365
Query: 439 CVHTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITT 498
+ + +C+EAE W +++F++L ++ PIDP K A+AI++ TT
Sbjct: 366 LIKDIDIVCREAECARWQKEIFDELSYKIPIPIDPLHSIIIGGVNISLKSNAAAIIITTT 425
Query: 499 SGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSG 558
+G+SA LLS YRPRCPI+AVTR+ AR + LY G+ + Y+E + SDW +D+ R+Q+G
Sbjct: 426 TGRSAVLLSMYRPRCPILAVTRYGVVARWLMLYFGIHSLHYKEESLSDWSQDIQTRIQTG 485
Query: 559 LRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVMLVQS 597
+ R++ ++ GD VV++GW+QG+GFTN VR++ V S
Sbjct: 486 IDSLRKKKYIKVGDAVVVISGWRQGAGFTNCVRIVYVSS 524
>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyruvate kinase -
Desulfuromonas acetoxidans DSM 684
Length = 474
Score = 326 bits (802), Expect = 8e-88
Identities = 191/490 (38%), Positives = 279/490 (56%), Gaps = 26/490 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I R K +
Sbjct: 1 MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
L P +AI D GP+IR G L G V L +G+ + L ++ + G D + VDY
Sbjct: 57 LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCSTG---QAGEGD-LPVDY 107
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
++ V+ G+ I + DGL+ + + + A + C++ +GG+ SRKGVN+P + +PA
Sbjct: 108 PSLHEDVQVGDSIMLSDGLMELQVERIDAPQVQCSVISGGVAYSRKGVNMPSSHLSIPAF 167
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+EKD+ DL FG++QGVD++ SF+R L EIR +L E + K+++KIE Q + +++
Sbjct: 168 TEKDRDDLRFGLQQGVDIVALSFVRGADDLKEIRTMLAEVPEAPKLVAKIEKPQAVAHIE 227
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI+ D +M+ARGDLG+E+P E+V + QK +I + GK VI ATQML SMV PRPT
Sbjct: 228 EILDVVDVVMIARGDLGVEVPLEQVPVLQKQLIHKARLKGKAVITATQMLSSMVSNPRPT 287
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE +DVANAI DG D +MLS ETA GDYPV + I + E + + + +
Sbjct: 288 RAEAADVANAIYDGTDALMLSDETASGDYPVAATRMLDRIARSTEPHL--DSALSLIQDD 345
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
P ASAIV T SG +A +S++RP CP+I +T + Q R
Sbjct: 346 GNDPPQVSWAVGRAAVTLAEDLRASAIVAYTQSGFTASCVSRFRPDCPVIGLTTNEQRCR 405
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG---WKQG 583
Q++L GVLP+ EP + D D + +R V VV G W+ G
Sbjct: 406 QMNLLWGVLPVTI-EPCS-----DTDEMFEKAREEVIKRHLVAATQRIVVTAGTPLWQSG 459
Query: 584 SGFTNTVRVM 593
S TN ++V+
Sbjct: 460 S--TNLLKVI 467
>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
Protochlamydia amoebophila (strain UWE25)
Length = 598
Score = 321 bits (789), Expect = 3e-86
Identities = 197/487 (40%), Positives = 273/487 (56%), Gaps = 23/487 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPA ++ + +++ GMNVAR+NFSHG+ E H TI +EA +L P
Sbjct: 8 IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
LAI LDTKGPEIR G + G ++ L G+ +L + G+ + + NI +
Sbjct: 63 -LAIMLDTKGPEIRLGKIRDG---QIFLTVGQKWRLVKK---EVLGDESQVSIFPLNILD 115
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ G I DDG I+ S++ + I N GM+ S KGVN+P ++LPAV+EKD
Sbjct: 116 QLPVGTTILFDDGYIASRVIENSSEGVLVEINNSGMIRSSKGVNIPNTSLNLPAVTEKDI 175
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILG-EKGKNIKIISKIENHQGMVNLDEIIA 350
D+ FG Q +D+I ASF+R+ + EI+ +L EK +I +I+KIEN +G+ N D I+
Sbjct: 176 DDIRFGCSQDIDLIAASFVRSAEHVLEIKRLLADEKKTDILVIAKIENSEGVQNFDSIVQ 235
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
+DGIM+ARGDLG+E+P V QK MI + GKPV+ ATQMLESM+ PRPTRAE
Sbjct: 236 AADGIMIARGDLGVEVPLSHVPRLQKMMIRKSYLAGKPVVTATQMLESMINNPRPTRAET 295
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
SDVANAI D +MLSGETA G YPVE V+ M +I +EAEA + F+ V
Sbjct: 296 SDVANAIYDSTSAIMLSGETAIGRYPVETVNVMRSIVEEAEADFNYSTFFDQHAPLVYHD 355
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+ + A AI T +G +A LLS+ RP+ PIIA+T + Q+
Sbjct: 356 VPSAVTLATVKTAYSSS--AKAIFAFTKAGTTARLLSRLRPKMPIIAMTAKEKIFHQLAF 413
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTV 590
GV+P + EP S D + S G Q V GD V+ G GF+ T
Sbjct: 414 NWGVIPFL-SEPCNS---LDKSLKKISDFALGSQH--VSYGDLVVITAG--TPFGFSGTT 465
Query: 591 RVMLVQS 597
+M+V++
Sbjct: 466 NMMIVEN 472
>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 509
Score = 321 bits (789), Expect = 3e-86
Identities = 193/495 (38%), Positives = 274/495 (55%), Gaps = 26/495 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGPA A ++++M GM+VAR+NFSHG+H+ H I+ R+
Sbjct: 20 RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
S+ I D +GP+IRTGLL+ V L+ G T+ +T G+A + ++
Sbjct: 78 ----SICILQDLQGPKIRTGLLKD--HKPVMLETGNTVTITPRDIV---GDASLLATTFQ 128
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ V+PG+RI + DG I + + + C I NGG L +G+N+PG + +PA++
Sbjct: 129 TLALDVQPGSRILLSDGKIELSVSRIEGADVECHIVNGGELKEHQGINIPGAILSIPALT 188
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
KD DL FG++ GVD + SF+R L ++R + E N+ +I+K+E Q + +L+E
Sbjct: 189 NKDLEDLAFGLKNGVDAVAISFVRTANDLKQVRNAISEHQGNVFVIAKLEKPQAIEHLEE 248
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I E+DG+MVARGDLG+E+PPEKV + QK +I R PVI ATQMLESM+ PRPTR
Sbjct: 249 IFNETDGVMVARGDLGVEVPPEKVPVLQKHIIKRSQSRRIPVITATQMLESMIDNPRPTR 308
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA---VIWHRQLFNDLV 464
AE SDVANAI DG D VMLSGETA G YP E V MA I EAE+ R+ D
Sbjct: 309 AEASDVANAIFDGTDAVMLSGETASGKYPREAVAMMARIITEAESHCLAEGRRRRHEDHK 368
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQT 524
+ + + AI + T SG +A +LSK+RP+ PI A +
Sbjct: 369 NTISEAVCDAVSHAAEDLDML------AIAIYTESGNTARILSKHRPKPPIYAFSHLDTV 422
Query: 525 ARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGS 584
+++L+ GV P V EP S K++ + L Q V GD VV G + S
Sbjct: 423 INRLNLFWGVHP-VQCEPLRSS--KEMILYAEQLLLGAHQ---VAAGDIIGVVAGTRSTS 476
Query: 585 GFTNTVRVMLVQSAS 599
G TN +R+ ++ S S
Sbjct: 477 GSTNFMRLHVIGSES 491
>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
bacteriovorus
Length = 495
Score = 318 bits (781), Expect = 3e-85
Identities = 185/490 (37%), Positives = 278/490 (56%), Gaps = 25/490 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ TIGPA+R+ LEK ++ GMNVAR+NFSHGSHE H + + + R+ K A +
Sbjct: 5 RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQAPV 64
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
AI D +GP+IR G E G +E+K GE + +TT+ + G + D++
Sbjct: 65 ------AILQDLQGPKIRVGKFENGS---IEIKPGEKLVVTTA---KVLGKPGLVPSDFQ 112
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ PG RI +DDGL+ + V + + + GG+L RKG+NLPG+ + + ++
Sbjct: 113 ELPLACVPGTRILLDDGLMEVKVLQVRGEEIDVEVVYGGILKDRKGMNLPGVNLPVDCMT 172
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
KD DL FG+ VD I SF+R+ + ++R ++ N KI++KIE + + NL+E
Sbjct: 173 PKDLEDLQFGIANKVDYIALSFVRHARDIRKLRELIEAGNSNAKIVAKIEMVEAIENLEE 232
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I SD +MVARGDL +E+ ++ QK +I+ CN++GKPVI ATQML+SMV+ PRPTR
Sbjct: 233 ICRLSDAVMVARGDLAVEVGQSRLPGYQKRIISVCNQLGKPVITATQMLDSMVENPRPTR 292
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AEI+DVANA+LDG D +MLS E+A G YP +C+ TM I E E + + + + E
Sbjct: 293 AEITDVANAVLDGTDALMLSAESASGKYPFKCIRTMHEIITEVER---NEEEYYKISLEN 349
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ P K A+AI+ +TTSGK+A+++S +RP+ II+VT+H
Sbjct: 350 EFLSTP-ASIAASASLSALKLNATAIICLTTSGKTANIISAFRPKARIISVTQHLDVLNG 408
Query: 528 VHLYRGV-LPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGF 586
+ L G+ + T D L++VD + S G GD ++ G G
Sbjct: 409 MELGWGIQTHAIKPYKTMEDILREVDLLLVS-------HGLGKTGDRVILTLGQPIACGA 461
Query: 587 -TNTVRVMLV 595
TN++ V V
Sbjct: 462 KTNSIYVHTV 471
>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
Pyruvate kinase - Leptospira interrogans
Length = 478
Score = 318 bits (780), Expect = 4e-85
Identities = 188/469 (40%), Positives = 270/469 (57%), Gaps = 23/469 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPAS + + +++ GM++ARMNFSHG+H+ H R+ E+ + F
Sbjct: 14 IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
L I D +GP+IRTG L+ + L K + I++ SD G+ I Y N+
Sbjct: 68 PLGIMADLQGPKIRTGKLKLNS---ILLHKNQEIEIVPDSDIL--GDEHKIGCTYPNLIR 122
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
++ ++I IDDG + + S +++ + GG+L S KG+NLPG P+ PA+SEKD
Sbjct: 123 DIQEEDKILIDDGKLILKVISKKSNSAILKVIVGGILWSNKGINLPGTPISAPALSEKDI 182
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
DL F + GVD SF+R GA L R L +G +I+KIE + + N++EII
Sbjct: 183 EDLKFALSLGVDYAALSFVRTGADLELARSYL--EGTYTGLIAKIERPEAIGNIEEIIER 240
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+DGIM+ARGDLG+EI EKV + QK +I + N+ GKPVI ATQMLESM++ PRPTRAE S
Sbjct: 241 ADGIMIARGDLGVEIDTEKVPILQKELIYKLNQAGKPVITATQMLESMIENPRPTRAEAS 300
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DVANA++DG D VMLS E+A G YPVE V M+ I +E E + ++ + K +
Sbjct: 301 DVANAVMDGTDAVMLSAESANGHYPVESVEIMSKIIQETETI---DHIYEIHWNIKKTFL 357
Query: 472 DPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+ + A AIV T SG SA + S+ RP+ PI + T TAR++ L
Sbjct: 358 ESERTALGNAAREIAHGIHAKAIVNFTRSGYSALITSEMRPKVPIYSFTPFATTARKMKL 417
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
YRGV+P V T L+D+ + L ++ F+ PGD V+++G
Sbjct: 418 YRGVVPFVMPFFTR---LEDMIAYMNQKL---KEDEFLFPGDKVVILSG 460
>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 481
Score = 317 bits (779), Expect = 5e-85
Identities = 189/474 (39%), Positives = 267/474 (56%), Gaps = 26/474 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + IICT+GPAS V+E ++ GMNVAR+NFSHG +E H + R+ S K
Sbjct: 16 MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG P +AI D +GP+IR G EGG ++ ++ G+T+ +TT + G I
Sbjct: 72 LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTTRAVL---GQGTLIPTPV 123
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+++T V G+ I +DDG + + V+ +T T+E GG+L KG+NLPG + +P +
Sbjct: 124 RSLTRDVTRGDMILLDDGRVRLRVVRVAGRDVTATVEVGGLLKDHKGLNLPGAAISVPTI 183
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+EKD DL FG E GVD + SF+R +H+ R + + +I+KIE Q + NL+
Sbjct: 184 TEKDAEDLAFGQELGVDYVALSFVRTANDIHQARTHVSKL--KTPLIAKIEKPQALENLE 241
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
I +DG+MVARGDLG+E+P E++ QK M+A NR G VI AT+MLESMV RPT
Sbjct: 242 AISEAADGVMVARGDLGVEMPLEQLPGIQKRMVAEVNRKGGLVIVATEMLESMVGNARPT 301
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE+SDVANAILDGAD VMLSGETA G YP++ TMA I +E E R L + L
Sbjct: 302 RAEVSDVANAILDGADAVMLSGETAAGKYPIDAAATMARIVEETE-----RSLPSSLRPS 356
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLA-SAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
+K + L IV T G +A L+S++RP+ II +T + T
Sbjct: 357 LKVGTQDLSAGVAAAAVAAAEQLGIGTIVAYTERGHTARLISEFRPKARIIGLTPNADTV 416
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
++ LY GV + L+ D ++ R R++ F PG V+V G
Sbjct: 417 NRMALYWGV------QGRQVTRLQSTDAMLKQVRRLCREQAFCEPGSPVVIVAG 464
>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Deinococcus radiodurans
Length = 482
Score = 316 bits (775), Expect = 2e-84
Identities = 189/486 (38%), Positives = 268/486 (55%), Gaps = 22/486 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPASR+ VL +M++ G+NV R+NFSHG E H +T++ R+ S +
Sbjct: 6 RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G I D +GP+IR G G V L G+ +T + +GNA+ + YK
Sbjct: 66 G------ILQDLQGPKIRVGRFAEGS---VTLNPGQKFVITMD---EVEGNAERVGSTYK 113
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ V PG + +DDG +S+ V + + T+ GG L + KG+N+P + +PA+S
Sbjct: 114 GLAGDVTPGMTLLLDDGNMSLRVDHVRGNDIQTTVLIGGTLKNNKGINVPEADLTVPALS 173
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD D+ FG GVD + SF+R+ L R L G K+++KIE Q + +
Sbjct: 174 EKDVQDMEFGASLGVDWVALSFVRSRDDLLLARHYLARFGSRAKLMAKIEKPQAVDRFAD 233
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ E DG+MVARGDLG+E+ PE+V QK +I C GKPVI ATQMLESM+ PRPTR
Sbjct: 234 ILKEVDGVMVARGDLGVEMRPEQVPTIQKRIIRMCREAGKPVITATQMLESMINLPRPTR 293
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVANAI DG D VMLS E+A G YPVE V M I +EAEA ++ + +V +
Sbjct: 294 AEASDVANAIYDGTDAVMLSAESAAGQYPVESVAMMDRIAREAEASELYQLMQRQVVMDT 353
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ D K A AIV T++G +A +SK RP I+A+T + T Q
Sbjct: 354 EQAQD---AIALAACNIGAKLEAPAIVTFTSTGGAATRISKNRPPLAIVALTPNEITRNQ 410
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGF 586
+ L GV P++ ++P +D D+ V+ ++ G GD V+ G G G
Sbjct: 411 LALSWGVYPMLSEDP------EDTDDMVRIANDELKKSGLADVGDRYVITAGVPFGVRGT 464
Query: 587 TNTVRV 592
TN +RV
Sbjct: 465 TNMLRV 470
>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
Pyruvate kinase - Anabaena sp. (strain PCC 7120)
Length = 476
Score = 316 bits (775), Expect = 2e-84
Identities = 190/488 (38%), Positives = 278/488 (56%), Gaps = 23/488 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + IICT+GPA+ LE ++E GMNVAR+NFSHG++++HA+T + R+ SA
Sbjct: 1 MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQI----SAD 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA-DTIYVD 225
P +AI D GP+IR G L G + ++ G+ + QEKG++ D + +
Sbjct: 57 RQKP--VAIMQDLCGPKIRLGTLPPEG---LMVEAGQEVTFVL----QEKGSSLDELPLP 107
Query: 226 YKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
+ +V+PG I I+DG + +I AD + + GG+L +RKGVNLP + + +
Sbjct: 108 LPTLFAMVRPGEPILINDGRVKLIVTDRDADRIRAIAKIGGLLSTRKGVNLPATRLPVSS 167
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
++EKD DL FG++ VD + SF+R+ L + ++ GK I++I+KIE + + +
Sbjct: 168 ITEKDLQDLRFGIDLSVDWVAVSFVRSPYDLEPAQRMIEAAGKTIRVIAKIERPEAVEQI 227
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
D II +D IM+ARGDLG+E+P +V L QK +I RCN+ GKPVI ATQMLESM+ P P
Sbjct: 228 DSIIDVADAIMIARGDLGVEMPIHEVPLIQKDIIRRCNQAGKPVITATQMLESMISAPDP 287
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
TRAE +DVAN+ILDG D VMLSGETA G YPV V M +I E + ++ +S
Sbjct: 288 TRAEATDVANSILDGTDAVMLSGETAVGQYPVAAVQVMHDIAVTTEKSL--QEGSKHCLS 345
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
+ + A AI+ TTSG +A L+SKYRP PI A+T
Sbjct: 346 HEAGGLSVTESVAEAVCRIAYETGAKAILCNTTSGSTAKLVSKYRPTTPIFALTPDETAY 405
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-S 584
Q+ L GV P++ P + + N + + +R G VH GD V+ +G G S
Sbjct: 406 HQLALSWGVEPLL--TPPVHNAEEMFMNLINTAVR----TGLVHDGDKVVITSGVPIGKS 459
Query: 585 GFTNTVRV 592
G T+ ++V
Sbjct: 460 GTTSLIKV 467
>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 477
Score = 314 bits (771), Expect = 5e-84
Identities = 190/487 (39%), Positives = 264/487 (54%), Gaps = 27/487 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPAS + ++ K+M GMNVAR+NFSHG E H+ +R R+ + +LG
Sbjct: 10 IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
++AI D GP+IR G LE V L KG I LT GN + I V YK +
Sbjct: 64 TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLTIDDT---PGNEERIPVSYKQLPE 117
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V PG+ I++ DG I ++C+ V+ + C + GG L S KG+NLPG + L AV+EKD
Sbjct: 118 SVTPGSLIYLSDGFIQLLCKEVTGKDVLCEVLIGGELYSHKGLNLPGAKIFLDAVTEKDF 177
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
L F +E+ +D SF+ N + ++R +GK + I+SKIE Q + N+ EI+ E
Sbjct: 178 RILEFALEEDIDTFSISFVENAEDIRKVRNFAASRGKQVNIVSKIERRQAVENIGEILDE 237
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+D +MVARGDLG+EIP ++V QK +I R +G PVI AT ML SM RPTRAE +
Sbjct: 238 TDALMVARGDLGVEIPIQEVPSVQKELIQRAKLLGVPVITATHMLASMTDNIRPTRAEAT 297
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKP-- 469
DVANAILDG D VMLS ETA G+YPVE V MA I K E W + L + +K
Sbjct: 298 DVANAILDGTDAVMLSEETAVGNYPVEAVEMMAKIAKTTEN--WRSRTKWGLDTMIKSIT 355
Query: 470 --PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ K +A++ T SG + +S++ P I+A +R P+T R
Sbjct: 356 AREMSVDEVITLQVYEALQKLPVAAVLTPTRSGATPRRISRFNPDPWILAFSRVPKTCRF 415
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGS-GF 586
+ L GV P+ E S W K+ R ++ GF D + G G G
Sbjct: 416 LSLSYGVYPVAVNESIES-WEKETTERT-------KELGFAKSKDLVIFTQGPASGKPGG 467
Query: 587 TNTVRVM 593
TN ++++
Sbjct: 468 TNMLKIL 474
>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 610
Score = 313 bits (769), Expect = 8e-84
Identities = 189/504 (37%), Positives = 273/504 (54%), Gaps = 26/504 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CT+GPAS +V + + + GM+VAR+N SHGS E+ E I R+ +++
Sbjct: 15 MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEEP 74
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+ A LD GPE+RT ++ ++L +G TI+ D A V
Sbjct: 75 V------AAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD------ATPEEVGL 118
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
V+PG+R+ +DDG I + V +T+ T+ENGG L +RKGVN+PG+ +DLP +
Sbjct: 119 SQSITAVEPGDRVLLDDGRIETTVERVEDETVFATVENGGELAARKGVNVPGVELDLPTI 178
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+E D+ +L E+ D + ASF+R+G ++EI L E+G +I II+KIE + NLD
Sbjct: 179 TENDEQELDVAAEKEPDFVAASFVRDGEDIYEISQALEERGVDIPIIAKIERAGAVENLD 238
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
II E+ G+MVARGDLG+E P E V + QK +I RC+ G PVI AT+ML+SMV RPT
Sbjct: 239 SIIDEAYGVMVARGDLGVECPLEDVPIIQKRIIRRCHEAGVPVITATEMLDSMVHSRRPT 298
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVANA+LDG D VMLSGETA GD+P V TM I ++ E +
Sbjct: 299 RAEASDVANAVLDGTDAVMLSGETAIGDHPARVVETMDRIIRDVEG---SEEYAESREQR 355
Query: 467 VKPPIDPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
V D + + ASAIV + SG +A +KYRP PI+A T +
Sbjct: 356 VPNAGDTRTDALARSGRFLARDIGASAIVAASESGYTALKSAKYRPSIPIVASTPSERVR 415
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSG 585
R++ L G+ P+ + T + D +Q+ ++ GD VV++G
Sbjct: 416 RKLALSWGITPVTTEYTT-----EGADAVIQTAVQAALDTEAADSGDTVVVLSGMMTELE 470
Query: 586 FTNTVRVMLVQ-SASMHTDGRKAV 608
NT ++ V +A GR V
Sbjct: 471 GMNTANMLKVHVAAETVASGRSIV 494
>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 619
Score = 312 bits (767), Expect = 1e-83
Identities = 200/519 (38%), Positives = 282/519 (54%), Gaps = 47/519 (9%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ TIGPAS N A+L +M+ G R+NFSHG HE H +IR R+ + L
Sbjct: 8 RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G +AI D +GP+IR G G + LK G+ LT+ G+ + +V Y
Sbjct: 64 G--IQVAILQDLQGPKIRLGKFAEGS---ITLKAGDPFVLTSKPVL---GSQERSWVTYD 115
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
+ V G I IDDG + + ++V A L C GG L + KGVN PG+ + + A
Sbjct: 116 KLAQEVPEGATILIDDGRVEMRVEAVDPEAGELFCRTIVGGTLSNNKGVNFPGVRLSIRA 175
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL--------GEKGKNIKIISKIE 337
V+ KDK DL FG+ QGVD + SF+R+ + + E+R ++ G K + II KIE
Sbjct: 176 VTPKDKEDLYFGLNQGVDWVALSFVRDPSDVLELRELIASAKRPSSGSADKRVPIIVKIE 235
Query: 338 NHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLE 397
H+ + L +I+A SDG+MVARGDLG+E+P E+V + QK +IA N +G PVI ATQML+
Sbjct: 236 KHEAIEQLPQILALSDGVMVARGDLGVELPAEEVPILQKRVIALANSLGIPVITATQMLD 295
Query: 398 SMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIW-- 455
SMV PRPTRAEISDVANAILDG D VMLS ETA G YPVE V TMA I E +
Sbjct: 296 SMVHSPRPTRAEISDVANAILDGTDAVMLSNETAVGKYPVEAVATMARIAVRTERDYFDL 355
Query: 456 ----HRQLFNDLVSE------------VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTS 499
RQ L + ++P + A A++ +T +
Sbjct: 356 TYADRRQRLRALAMQELSQNNGNSPAGMRPKTLITDSISRAVGEIAQELDAVAVMTLTKT 415
Query: 500 GKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGL 559
G +A +SK+RPR PI+AVT H + AR++ L GV P++ + L Q+ +
Sbjct: 416 GATARNVSKFRPRTPILAVTPHVEVARRLQLVWGVHPLLVMD------LATTRQTFQAAI 469
Query: 560 RFGRQRGFVHPGDNAVVVTGWKQG-SGFTNTVRVMLVQS 597
++ G + GD V+ G G +G T+ ++V +V++
Sbjct: 470 SLAQEDGLLKDGDLVVLSAGTLPGVAGSTDLIKVDVVKA 508
>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
PR1
Length = 476
Score = 312 bits (766), Expect = 2e-83
Identities = 179/447 (40%), Positives = 256/447 (57%), Gaps = 23/447 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ TIGPAS N + + G NV R+NFSHGSH+ H E I R+ K + LG
Sbjct: 11 ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
I D +GP+IR G +E G VE+K GE K+T ++D G + + Y+N+
Sbjct: 68 ---ILQDLQGPKIRVGEVENNG---VEIKPGE--KITITND-PVVGTSTLVSTVYQNLPQ 118
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V G+RI IDDG + ++ + CT+ +GG+L SRKG+NLP V P+++EKD
Sbjct: 119 DVVSGDRILIDDGNLEVVVNDTDGKNVNCTVIHGGILKSRKGINLPNTKVSAPSLTEKDI 178
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
DL FG+ + VD I SF+R+ + ++R + KGK+ KI++KIE + + N+D II
Sbjct: 179 EDLAFGLSKEVDWIALSFVRSAEDIEDLRERIEAKGKHCKIVAKIEKPEALENIDGIIEA 238
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+D IMVARGDLG+E+P E V L QK ++ +C KPVI ATQM+ESM+ PRPTRAE +
Sbjct: 239 TDAIMVARGDLGVEVPMEIVPLWQKRIVEKCKLACKPVIIATQMMESMIVNPRPTRAETN 298
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DVANA+LDGAD VMLS ETA G YPV V M++I EA + +++++L K P
Sbjct: 299 DVANAVLDGADAVMLSAETASGKYPVNAVKAMSSIIGYLEA---NAEIYHNL---YKIPE 352
Query: 472 DPXXXXXXXXXXXXTK----CLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
D ++ A AIV IT+SG + ++ +RP I T + Q
Sbjct: 353 DDDTFLSNNLILMASRLSRNVKAKAIVGITSSGFTGFRIASHRPLANIFVFTSNKTLITQ 412
Query: 528 VHLYRGVLPIVYQEPTASD-WLKDVDN 553
+ L G+ Y + ++D D++N
Sbjct: 413 MSLVWGIRAYFYDKLVSTDATFVDIEN 439
>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
Pyruvate kinase - Propionibacterium acnes
Length = 477
Score = 311 bits (764), Expect = 3e-83
Identities = 181/495 (36%), Positives = 280/495 (56%), Gaps = 26/495 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPA + ++++ME GMN+AR+N SHG + H E + + +S S +
Sbjct: 1 MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLE---GGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 223
LG ++A D +GP+IRTGL E G + +++LK G+ +TT GN + +
Sbjct: 57 LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITTDDIV---GNQERVS 111
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 283
+K + KPG+ I IDDG + SVS + + C G +G KG+NLPG+ V +
Sbjct: 112 TTFKGLPQDCKPGDVILIDDGKTVLQVDSVSGNDVNCHCTVAGPVGDHKGINLPGVAVSI 171
Query: 284 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMV 343
PA+++KD+ +L + ++ G+D++ SF+R+G+ + + I+ E+G+ + +I+K+E Q +
Sbjct: 172 PALTKKDEENLRWALKAGIDLVALSFVRHGSDIDRVHEIMDEEGRTVPVIAKLEKPQAIE 231
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
NLDEII D +MVARGD+ +E P E+V L QK +I + KPVI ATQMLESM+ P
Sbjct: 232 NLDEIIDVFDAVMVARGDMAVECPLEEVPLIQKQIIEKARLQAKPVIVATQMLESMIHAP 291
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
RPTRAE +DVANAILDGAD VM S ET+ GD+P E V TMA I + EA R L D
Sbjct: 292 RPTRAEAADVANAILDGADGVMTSAETSVGDFPGETVRTMAKIVESTEA----RGL--DK 345
Query: 464 VSEVK-PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHP 522
++++ P + A IV T SG +A +++ RP P+I T
Sbjct: 346 IAKIDWDPHTTSGIMSKAAAEIAERAEAKFIVAFTKSGDTARRIARLRPSTPLIVFTSDE 405
Query: 523 QTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ 582
T + + G +V + K+ + + + R +GFV GD VV++G
Sbjct: 406 TTTKTLAWVWGAHAVV------TPVFKNAEELYRWVNAYLRDKGFVPVGDRVVVLSGSPM 459
Query: 583 G-SGFTNTVRVMLVQ 596
G TN +R++ ++
Sbjct: 460 DIPGKTNNLRILRIK 474
>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
uncultured delta proteobacterium DeepAnt-32C6
Length = 466
Score = 310 bits (760), Expect = 1e-82
Identities = 187/487 (38%), Positives = 263/487 (54%), Gaps = 26/487 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CTIGPA+ + +++ GM+ AR+NFSHG+ + HA RE + +
Sbjct: 1 MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVREL----ATE 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
G P +A+ D GP+IR G G VEL +G LTT G ++Y
Sbjct: 57 AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTTRD---VAGTDKQASINY 108
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ V PG+ I IDDGLI ++ + V + C +E GGML RKG+N+PG + PA+
Sbjct: 109 AALPQDVDPGDAIMIDDGLIRLVVREVEGPDIHCIVEVGGMLSERKGINVPGSALSTPAL 168
Query: 287 SEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
++KDK DL F V+ GVD I SF+R A + E + + KN +I+K+E + + NL
Sbjct: 169 TDKDKRDLAFAVDTIGVDWIALSFVRTAADILEAKSL----AKNTPVIAKLEKPEAIANL 224
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
I +DG MVARGDLG+E+ PEKV L QK +I N GK VI ATQML+SM++ PRP
Sbjct: 225 CAIADVADGAMVARGDLGVELGPEKVPLVQKRIIEEVNTRGKLVITATQMLDSMIRNPRP 284
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
TRAE +D+ANA+LDG D +MLSGETA G YP++ V M I +E E + V
Sbjct: 285 TRAEAADIANAVLDGTDALMLSGETAVGRYPIKAVKMMDVIIREVETAWLKDASMKEQVI 344
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
K A+VV T G++ LLS+YRPR PIIA+T + A
Sbjct: 345 ADKWGFATATTKAAALLSFVLD--LKALVVFTQDGRTVQLLSEYRPRAPIIALTSDSRVA 402
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSG 585
Q+ L GV P + P +++ V+ G + G GD+ +V GW
Sbjct: 403 NQLALEWGVYPRLEVPP------EELSEAVRIGTGLVLRHGICAVGDDIALVLGWPVRES 456
Query: 586 FTNTVRV 592
TNT+++
Sbjct: 457 -TNTLKL 462
>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
pacifica SIR-1
Length = 485
Score = 309 bits (758), Expect = 2e-82
Identities = 183/478 (38%), Positives = 267/478 (55%), Gaps = 25/478 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPAS + ++ +M+ G++ R+NFSHGSHE HA+ RE + S +
Sbjct: 6 LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+A+ D +GP+IR G + G + L+ GET+ T D + + + +DY
Sbjct: 65 -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLT--DPTAEISQGRVTIDY 114
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ K G R+ +DDG + ++A + + NGG+L +RKGVNLP + LP++
Sbjct: 115 PTLDEEAKVGERVLMDDGELEARITEINAGEVHAEMLNGGVLKARKGVNLPDSDLLLPSL 174
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMV--N 344
++KD DL F +E GVD + SF+R L E R I+ E G+ + +++KIE + + N
Sbjct: 175 TDKDAKDLRFALELGVDFVALSFVRRVEDLEECRKIMNEVGRTVPLVAKIEKPEALEPEN 234
Query: 345 LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPR 404
L +I+ ++GIM+ARGDLG+E+ PE+V L QK +I N GK VI ATQML+SM++ PR
Sbjct: 235 LPKILDAANGIMIARGDLGVEMGPEEVPLIQKELIKLSNERGKLVITATQMLDSMIRNPR 294
Query: 405 PTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLV 464
PTRAE SDVANAILDG+DCVMLSGETA G YP+ V TM I + E + D
Sbjct: 295 PTRAEASDVANAILDGSDCVMLSGETAAGKYPIRAVETMDRIIRRIEKT---ETYWLDPP 351
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQT 524
+++ + AI+ T SG A L+S YRP+ PI A T P T
Sbjct: 352 KDMQLGHTTNAVARAAVTSSRSLPDCKAIICYTGSGGIARLVSDYRPKVPIYAFTPQPST 411
Query: 525 ARQVHLYRGVLPIVYQ--EPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGW 580
+ + LY GV+PI +Q P + D+D+ V F R GD V+ GW
Sbjct: 412 FQALALYWGVIPIRFQPSTPGGENIFIDLDHGVLDRKMFER-------GDRVVIALGW 462
>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
(strain DSM 13855)
Length = 476
Score = 307 bits (754), Expect = 5e-82
Identities = 181/492 (36%), Positives = 264/492 (53%), Gaps = 21/492 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CT+GPA+ + L +++ GM+VARMNFSHG+HE H E + RE ++
Sbjct: 3 RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
+ + D +GP+IR G ++ V L +G+ ++++T D + + I++DY+
Sbjct: 61 ----GITVLQDLQGPKIRVGAVQNDS---VMLAEGDEVRVST--DTPRESTNEHIFIDYE 111
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ + G RI IDDGL+ + + L T+ GG L SRKGVNLP + P ++
Sbjct: 112 ALARDAREGERILIDDGLLELRVIETNGSQLRATVVEGGPLRSRKGVNLPDLQASTPPMT 171
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD DL G+E VD++ SF++ + + + + E GK +++KIE Q + N+DE
Sbjct: 172 EKDLKDLELGLELEVDVVALSFVQERSDVEALVHRIEETGKKTSVVAKIEKPQAVHNIDE 231
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ DGIMVARGDLGIE+P E+V QK +I + KPVI ATQMLESMV+ PRPTR
Sbjct: 232 ILEVVDGIMVARGDLGIEMPMEEVPGTQKRLIRKSMEAAKPVITATQMLESMVEDPRPTR 291
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWH--RQLFNDLVS 465
AE SDVANA+LDG+D VMLS ETA GD+PV V M I ++AE+ WH R+
Sbjct: 292 AEASDVANAVLDGSDAVMLSAETAVGDHPVRVVEAMNQIIRQAES-YWHEERRALTMTPD 350
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
+ + + A AI +T SG +A ++++RP PI A T + +
Sbjct: 351 HFEQGANVTNSVSFTACRLAEQVGAEAICCLTNSGSTARSIARHRPSMPIYAFTDNKRVV 410
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWK-QGS 584
Q+ G E + +D D + V G + V+ G
Sbjct: 411 AQLGSLWGT------EAFYIPFQQDTDQGIARVHGVLHDYDLVRSGGHVVLTVGMPLPAR 464
Query: 585 GFTNTVRVMLVQ 596
G TNTV V VQ
Sbjct: 465 GRTNTVHVSTVQ 476
>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 477
Score = 306 bits (752), Expect = 9e-82
Identities = 182/494 (36%), Positives = 281/494 (56%), Gaps = 28/494 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPA+ + + ++ G++V R+NFSHG+H+ H + R REA +A+
Sbjct: 3 VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
G ++AI D +GP+IRTG +EGG EL +G + + D+ G+A + Y
Sbjct: 59 AGR--NVAIMQDLQGPKIRTGEVEGG----TELVEGSRVVIAPG-DFV--GDASRLSTSY 109
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSAD-TLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
+ VKPG+R+ IDDGLI + +S+ + + C + GG + S KG+N P + +
Sbjct: 110 DRLAQDVKPGHRLLIDDGLIGLRVESIKENGEIVCEVLEGGPVSSHKGLNFPDSSLSISG 169
Query: 286 VSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVN 344
++EKD DL FG+E+ D + SF+R G + +++ + E G ++ +ISKIE H+ + N
Sbjct: 170 LTEKDLEDLRFGLEELRPDWVAISFVRTGEEVLDVKERIRELGGDVPVISKIEKHEAIDN 229
Query: 345 LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPR 404
++E+I SDG+MVARGDL +E+ E+V + QK ++ARC R G+PVI ATQML+SM++ PR
Sbjct: 230 IEEVIEASDGVMVARGDLAVELSAERVPIEQKRIVARCRRRGRPVIVATQMLDSMMRNPR 289
Query: 405 PTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLV 464
PTRAE+SDVANAI D D VMLSGETA G YP + V M IC+ AE I + + D+
Sbjct: 290 PTRAEVSDVANAIFDRTDAVMLSGETAVGRYPTQSVMEMDRICRAAEGAIDYGR---DIA 346
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
+ + L A AI+ T +G S ++++RP I+AV+
Sbjct: 347 ASTAWGRGDRYDAVTHAACELAEVLEAQAILTSTQTGLSCIRVARFRPPNRILAVSPIEA 406
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG 583
T R++ L GV + + ++ R + + RG + GD +V TG G
Sbjct: 407 TVRRLALVWGVTAV------RGEQAGSIEERFRESVEAAEARGHLKKGDR-LVFTGGTAG 459
Query: 584 S--GFTNTVRVMLV 595
S G TN ++V V
Sbjct: 460 SLPGSTNLLQVHTV 473
>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
Pyruvate kinase - Methanosarcina acetivorans
Length = 489
Score = 305 bits (750), Expect = 2e-81
Identities = 182/487 (37%), Positives = 260/487 (53%), Gaps = 27/487 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPAS + VL K++ GMNVAR+NFSHG E H + IR R+ +
Sbjct: 22 IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
++AI D GP+IR G L+ + L KG I LTT + G+ D I V+YK +
Sbjct: 76 TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTTD---ETSGSEDRIPVNYKQLPE 129
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V PG+ I++ DG I ++C +S + C + GG L S KG+NLPG + L +V+E D
Sbjct: 130 SVSPGSLIYLSDGFIQLLCLEISGKDVVCEVMVGGQLYSHKGLNLPGAKIYLDSVTEHDF 189
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
L F + + VD + SF+ + ++R GK + ++SKIE Q + N++EI+ E
Sbjct: 190 KILEFALNEEVDAVSISFVEKAEDIRKVRNFASTMGKPVYVVSKIERSQAVQNIEEILEE 249
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+D +MVARGDLG+EIP ++V QK +I + PVI AT ML SM RPTRAE +
Sbjct: 250 TDALMVARGDLGVEIPIQEVPSVQKELIRSAKLLSIPVITATHMLASMTDNIRPTRAEAT 309
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE----AVIWHRQLFNDLVSEV 467
DVANAILDG D VMLS ETA G+YPVE V MA I K E W ++
Sbjct: 310 DVANAILDGTDAVMLSEETAVGNYPVETVEMMAKIAKTTENWRSRTKWGLDTMLKGITAQ 369
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
K +D K + ++ T SG + LS+++P I+A TR P+T
Sbjct: 370 KMSVD--EVIALQVHEALQKLPVAVVLTPTRSGATPRRLSRFKPEPWILAFTRFPKTCSS 427
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGS-GF 586
+ L GV PI+ +E + +W + + ++ GF G+ V G G G
Sbjct: 428 LALSYGVYPIIVKE-VSENWETETTEK-------AKELGFAKSGELVVFTQGPASGKPGG 479
Query: 587 TNTVRVM 593
TN ++++
Sbjct: 480 TNMLKIL 486
>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
araneosa HTCC2155
Length = 485
Score = 304 bits (747), Expect = 4e-81
Identities = 172/436 (39%), Positives = 253/436 (58%), Gaps = 22/436 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+GP ++ L++++E G++V R+NFSHGSHE HAE I+ A +G
Sbjct: 9 IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63
Query: 172 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 230
I D +GP+IR G ++EGG ++L+ G+ + +TT E T++ + +
Sbjct: 64 ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITTDEILGEGSRISTVF---QALP 113
Query: 231 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 290
VK G+ I +DDGL+ + + + + + C + G L S KG+NLP + PA++EKD
Sbjct: 114 REVKVGDPILMDDGLLEAVVERIEGNEIFCKMLVAGKLTSNKGINLPETDIQSPALTEKD 173
Query: 291 KSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 349
+ DL F +E +D + SF+R G L I + + GK +ISKIE +V++D II
Sbjct: 174 ERDLKFIIENDAIDFVALSFVRKGEDLDIIHAAMDKIGKRKPVISKIEKPSALVDIDAII 233
Query: 350 AESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAE 409
+SD +MVARGDLG+EIP EKV +AQKTMI +C GKP I ATQML+SM++ PRPTRAE
Sbjct: 234 EKSDALMVARGDLGVEIPSEKVPVAQKTMIRKCIEQGKPCIVATQMLDSMIRNPRPTRAE 293
Query: 410 ISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQ-LFNDLVSEVK 468
SDVANA+LDGA VMLSGETA G YPVE V M I +E E + ++ E++
Sbjct: 294 ASDVANAVLDGASAVMLSGETASGSYPVEAVQMMTKIIRETERNFMTKPGMWGYEQPEIR 353
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA-RQ 527
+D I+ IT +GK+A ++++RP CPI A H R+
Sbjct: 354 NDVDALCKSIVDLSETLN---VKGIICITNTGKTALRIARFRPACPIFAFASHENNVLRK 410
Query: 528 VHLYRGVLPIVYQEPT 543
+ L + V+P+ ++ T
Sbjct: 411 LSLPKAVVPMPLKDLT 426
>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
Length = 478
Score = 304 bits (747), Expect = 4e-81
Identities = 184/484 (38%), Positives = 270/484 (55%), Gaps = 23/484 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPA+++ +++K++ GMNVAR+N SH + H + + ++ K L PF
Sbjct: 12 IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI LD +GP+IRTG E + +V L++G+ LT + GN + + ++Y+ +
Sbjct: 68 --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILTIE---EIVGNKERVSINYRELPK 119
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VK G+ I +DDG I ++ S + + + GG + R+G+N+PGI + LP ++EKD
Sbjct: 120 EVKKGDFILLDDGKIRLVVVSSNEKEIVTKVVTGGSITHRRGINVPGIDISLPPLTEKDM 179
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLDEIIA 350
L VE VD I SF+R + R IL E G ++ II+KIE Q + NL+ II
Sbjct: 180 EYLNKAVEWNVDYIAQSFVRKAEDITRTRRILTELGMPDLPIIAKIETLQALDNLESIIE 239
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
E+DG+MVARGDLG+E P E++ L QK +I N + KP I ATQMLESMV P PTRAE
Sbjct: 240 EADGVMVARGDLGVEAPVEQIPLLQKRIIEIANTMAKPAITATQMLESMVNNPFPTRAEA 299
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
+D+ANAILDG D VMLS ET+ G YP + V MAN+ KE E ++ + +
Sbjct: 300 TDIANAILDGTDAVMLSEETSIGKYPEQAVKVMANVAKETEKIL--EEYYYKFDYSTYGG 357
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITT-SGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
DP + L ++V TT SG +A LS++R I+A + T ++
Sbjct: 358 GDPATNSITMSAIKIAEQLGIDVIVATTYSGYTARALSRFRRNIKIVAASPRITTYHRLA 417
Query: 530 LYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFTN 588
L GV P++ Q+ T D DN ++S + F G+N +V G G S TN
Sbjct: 418 LIWGVTPVIMQKFT------DTDNMLESVSNIVKSLDFGVSGENIIVTAGIPYGFSSKTN 471
Query: 589 TVRV 592
++V
Sbjct: 472 LLKV 475
>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
Length = 482
Score = 302 bits (742), Expect = 1e-80
Identities = 183/490 (37%), Positives = 266/490 (54%), Gaps = 25/490 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R S I+ T+GPAS + +L + G++ R+NFSHG+ HAE RN R E+ + A
Sbjct: 7 RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
++A+ D +GP+IR G+L G ++L +G TI + E N I + ++
Sbjct: 65 ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTIGFILGREGGEGMN--DIPLPHR 115
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
I V PG + IDDG I + V L C + NGG L +RKGVN+PG +D+ ++
Sbjct: 116 EIFEVAVPGMDLLIDDGRIKVRIMEVMDGRLVCEVLNGGALSNRKGVNVPGAVLDISPLT 175
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
KD+ DL FG+E GVD + SF++ + E R ++G++ +I+KIE + ++++
Sbjct: 176 AKDREDLEFGLELGVDWVALSFVQRARDMIEARSLVGDRAG---LIAKIEKPSALDDIED 232
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ SD +MVARGDLG+EIPPE V QK +I C KPVI ATQML+SMV P PTR
Sbjct: 233 IVRLSDSVMVARGDLGVEIPPEDVPGKQKEIIRACRLAAKPVIVATQMLDSMVSSPTPTR 292
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVA AI DGAD VMLS ETA G YPVE V M I ++ E +R + +V
Sbjct: 293 AEASDVAGAIYDGADAVMLSAETATGAYPVEAVEIMNRIIEKTEKHKHYRPILEATEPDV 352
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
P + +V T+SG +A +S+ RP PI+A+T Q AR+
Sbjct: 353 AQ--SPPHAVATAAANVAVALGSPVVVAYTSSGTTAARISRARPALPILALTPSEQVARR 410
Query: 528 VHLYRGVLPIVYQE-PTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWK-QGSG 585
++++ GV+ + Q+ T L VQ + P D+ V+V G+ G
Sbjct: 411 LNMFWGVVGVRSQDVHTYEASLIHAQQAVQ-------EAKLASPSDHIVIVAGFPFAQQG 463
Query: 586 FTNTVRVMLV 595
TN +RV+ +
Sbjct: 464 STNNLRVVQI 473
>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
Pyruvate kinase - Chlamydia trachomatis
Length = 485
Score = 301 bits (740), Expect = 3e-80
Identities = 191/487 (39%), Positives = 270/487 (55%), Gaps = 28/487 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
IICTIGPA+ +LEK+++ GMNVAR+NFSHG+HE H TI +E + L
Sbjct: 7 IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPL---- 62
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI LDTKGPEIR G +E + ++++ G+ + L + K + T+Y +
Sbjct: 63 --AIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVSKEILGSKESGVTLYPSC--VFP 114
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V+ + IDDG I + + + +N G + S K +++ I V LP ++EKD
Sbjct: 115 YVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIKDIDVALPFMTEKDI 174
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLDEIIA 350
+DL FGVEQ +D+I ASF+R + +R +L G+ N+ II+KIENH G+ N EI
Sbjct: 175 ADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIAR 234
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
+DGIM+ARGDLGIE+ +V QK M G+ I ATQMLESM++ P PTRAE+
Sbjct: 235 AADGIMIARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEV 294
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF--NDLVSEVK 468
SDVANAI DG VMLSGETA G +PV V TM +I +E E + F ND S +K
Sbjct: 295 SDVANAIYDGTSAVMLSGETALGAHPVHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALK 354
Query: 469 PPIDP-XXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ P K A AI+V T +G S LSKYRP PIIAVT + +
Sbjct: 355 --VSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPIIAVTPNRNVYYR 412
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFT 587
+ + GV P++ E + W R Q+ + +G ++G + D +V + +G+G
Sbjct: 413 LAVEWGVYPMLTLESNRTVW------RHQACV-YGVEKGILSNYDKILV---FSRGAGMQ 462
Query: 588 NTVRVML 594
+T + L
Sbjct: 463 DTNNLTL 469
>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 492
Score = 301 bits (739), Expect = 3e-80
Identities = 182/471 (38%), Positives = 265/471 (56%), Gaps = 23/471 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H REA + +L
Sbjct: 24 RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREAAQ----RL 79
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
P +AI D +G ++R G ++ S + L++G+ I L + E ++ I +DY+
Sbjct: 80 MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL----GHGETISSKRIGIDYQ 131
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+I V PG ++F+DD I + S+ L C ++ GG L SRKGV P + P ++
Sbjct: 132 DIIQYVTPGQKVFLDDASIELEVLSIEEKDLHCQVKFGGQLRSRKGVIFPDSQLSFPLLN 191
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLD 346
EKD +D FGV VDM+ SF+R+ + E+R L E G KN II+KIE+H+G+ NLD
Sbjct: 192 EKDATDARFGVFLDVDMVAMSFVRSATEIIEMRLRLAEWGQKNSFIIAKIEDHKGIDNLD 251
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI+ +DG++VARGDLG+ +P EKV QK +I + N G PVI ATQMLESM PT
Sbjct: 252 EILQVADGVLVARGDLGVTLPREKVPNIQKAIIQKANAFGVPVITATQMLESMTHHDIPT 311
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE++DV +A++ G+D VMLSGETA G YP++ V M IC+EAE + R + ++
Sbjct: 312 RAEVNDVYHAVIGGSDAVMLSGETASGRYPIQAVQEMNRICREAEKEL--RNVKGEIPVR 369
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
K + TK A I+ + SG + LS R P+ V + R
Sbjct: 370 GKQDMHDKMAASAVNLAHNTK--ARCILAFSLSGATLRALSSARSSVPVYGVVVEERLLR 427
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVV 577
Q+ L+ G I + ++N + L+ ++ +H D VV+
Sbjct: 428 QLLLHWGHSLITMPHE------ETLENLICPALKQLQEENIIHSNDRIVVM 472
>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
bacterium TAV2
Length = 480
Score = 301 bits (738), Expect = 5e-80
Identities = 176/475 (37%), Positives = 264/475 (55%), Gaps = 25/475 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
IR + I+ T+GPA+ + +LEK++ G +VAR+N +H +HE+ IR RE K +
Sbjct: 10 IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD--TIYV 224
+G +AI +D KGPEIRTG + S+ +ELK GE T + + + ++ V
Sbjct: 66 VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFTIRPGAAQDSSEEVRSVDV 119
Query: 225 DYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLP 284
+YK++ N ++ G+ + +D+GLI + + C + G L SR+ +NLPG+ V+LP
Sbjct: 120 NYKDLVNDIRVGDTVLVDNGLIRLEVLEKQNTRIRCRVLIPGELKSRRHINLPGVKVNLP 179
Query: 285 AVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVN 344
+++EKDK+DL G+ +G+D + SF+R A + +R +L II+KIE+ + N
Sbjct: 180 SLTEKDKTDLAVGLIEGIDFVALSFVREAADIQLLRDVLHRYKSRAGIIAKIEDQSAIAN 239
Query: 345 LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPR 404
LDEI+ +D +MVARGDLGIE P E++ + Q+ + C GKPVI AT MLESM+ P
Sbjct: 240 LDEIVRTTDALMVARGDLGIECPFEELPIIQRRAVRMCFDYGKPVIIATHMLESMIASPM 299
Query: 405 PTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLV 464
PTRAEI+DVANA+ + ADCVMLSGET G YP+ECV + I + E+ L + +
Sbjct: 300 PTRAEITDVANAVYEKADCVMLSGETTIGRYPLECVQILDKIARRIESEGPFELLDPETL 359
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPR-CPIIAVTRHPQ 523
K + +A++ T G A L+ RP PI A+T P+
Sbjct: 360 EGDKMRL------LQSAVHLAHDLEGAALLTFTRRGYMAAGLAAMRPAWAPIYAMTNSPE 413
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVT 578
T R + L RGV EP + D + + + +G V PGD +VVT
Sbjct: 414 TLRNLRLVRGV------EPFMLELAADPNETIDQAITLLTTKGRVKPGDKLIVVT 462
>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
Phytoplasma|Rep: Pyruvate kinase - Onion yellows
phytoplasma
Length = 446
Score = 300 bits (737), Expect = 6e-80
Identities = 179/430 (41%), Positives = 255/430 (59%), Gaps = 23/430 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
IICT+GPAS + +L+ +++TG+NVAR NFSH +E ++ K+ S KL
Sbjct: 6 IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ + LDTKGPEIRT +G V ++K +K++ + + GNA V Y N+ N
Sbjct: 60 NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKISMT---EVLGNAKLFSVSYSNLYN 112
Query: 232 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
+K G+ + IDDG +S ++ + + L +N + SR+GVN+P + +++ +S K
Sbjct: 113 ELKVGDMVNIDDGYLSLEVVGKDEAKQQLVTKAKNTHSIKSRRGVNVPKVNLEMDFISPK 172
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLDEI 348
D D++F +Q D I ASF+R + +IR IL E+G NI+IISKIEN +G+ NL+EI
Sbjct: 173 DYQDIVFAAQQDFDYIAASFVRRAQDVKDIRKILQEQGNSNIQIISKIENQEGVDNLEEI 232
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
I ESDGIMVARGDLGIE+ E V L Q MI +C GKPV+ ATQMLESM + PRPT+A
Sbjct: 233 IQESDGIMVARGDLGIEVDGELVPLYQTRMITKCLEYGKPVVVATQMLESMQRNPRPTKA 292
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
E SDV NA+ +G MLSGE+A G+YPVE V M I +AE V+ ++ L S+V
Sbjct: 293 ETSDVFNAVREGTTFTMLSGESASGEYPVEAVTYMKKINYQAEKVVNYQAL-----SQVY 347
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
P + + AIVV K A+ +SK+ P P++A+ + Q AR++
Sbjct: 348 QPKNSKENLLLSAVELALRTDVKAIVVYDL--KDAYNVSKFHPSVPVLALVKTEQEARRL 405
Query: 529 HLYRGVLPIV 538
L GV P V
Sbjct: 406 VLNFGVCPFV 415
>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
lactis subsp. lactis (Streptococcus lactis)
Length = 502
Score = 299 bits (733), Expect = 2e-79
Identities = 178/484 (36%), Positives = 268/484 (55%), Gaps = 25/484 (5%)
Query: 119 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 178
+++N+A L +E G NV R NFSHG H + AE+ K+G LD
Sbjct: 38 SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88
Query: 179 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNVVKPGN 237
TKGPE+RT L G A + + G+ ++ T + + V +I + V+ G
Sbjct: 89 TKGPEMRTELFADGADA-ISVVTGDKFRVATKQGLKSTPELIALNVAGGLDIFDDVEIGQ 147
Query: 238 RIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 295
I IDDG + + A T +E N G++G +KGVN+P + PA++E+D +D+
Sbjct: 148 TILIDDGKLGLSLTGKDAATREFEVEAQNDGVIGKQKGVNIPNTKIPFPALAERDDADIR 207
Query: 296 FGVEQ--GVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLDEIIAES 352
FG+ Q G++ I SF+R + E+R I E G ++++++KIEN QG+ NLDEII +
Sbjct: 208 FGLSQPGGINFIAISFVRTANDVKEVRRICEETGNPHVQLLAKIENQQGIENLDEIIEAA 267
Query: 353 DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISD 412
DGIM+ARGD+GIE+P E V + QK +I++ N+ GK V+ AT MLESM PR TR+EISD
Sbjct: 268 DGIMIARGDMGIEVPFEMVPVYQKLIISKVNKAGKIVVTATNMLESMTYNPRATRSEISD 327
Query: 413 VANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPID 472
V NA++DG D MLSGE+A G YP E V TMA + K A+ ++ + + L E
Sbjct: 328 VFNAVIDGTDATMLSGESANGKYPRESVRTMATVNKNAQTML---KEYGRLHPERYDKST 384
Query: 473 PXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYR 532
IV +T SG +A L+SK+RP I+A+T + R + +
Sbjct: 385 VTEVVAASVKNAAEAMDIKLIVALTESGNTARLISKHRPNADILAITFDEKVERGLMINW 444
Query: 533 GVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRV 592
GV+P + ++P+++D + +V +V G V GDN ++V G G+G TNT+R+
Sbjct: 445 GVIPTMTEKPSSTDDMFEVAEKV------ALASGLVESGDNIIIVAGVPVGTGRTNTMRI 498
Query: 593 MLVQ 596
V+
Sbjct: 499 RTVK 502
>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
(class)|Rep: Pyruvate kinase - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 475
Score = 298 bits (731), Expect = 3e-79
Identities = 175/491 (35%), Positives = 268/491 (54%), Gaps = 30/491 (6%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CT+GPA + + +++E GM+VAR+NFSHG H H + + REA + +
Sbjct: 3 RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G I D +GP+IR G G + + GETI++T +G D + YK
Sbjct: 63 G------ILADLQGPKIRLGRFTDGATV---WENGETIRITVDD---VEGTHDRVSTTYK 110
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
N+ KPG+R+ +DDG + ++C SV + + C + GG + + KGV+LPG+ + +PA+S
Sbjct: 111 NLAKDAKPGDRLLVDDGKVGLVCVSVEGNDVICEVVEGGPVSNNKGVSLPGMDISVPALS 170
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD DL F ++ GVD I SF+R+ A + I+ E+G+ + +I+K+E + + +L+
Sbjct: 171 EKDIRDLRFALKLGVDFIALSFVRSPADAELVHKIMDEEGRRVPVIAKLEKPEAVTSLEP 230
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ D +MVARGDLG+E+P E+V L QK I KPVI ATQML+SM++ RPTR
Sbjct: 231 IVLAFDAVMVARGDLGVEVPLEEVPLVQKRAIQIARENAKPVIVATQMLDSMIENSRPTR 290
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVANA+LDGAD VMLSGET+ G P V TM+ I + AE + V ++
Sbjct: 291 AEASDVANAVLDGADAVMLSGETSVGKDPHNVVRTMSRIVRFAET--------DGRVPDL 342
Query: 468 KP-PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
P + A A+V TTSG +A +++ P++ T +
Sbjct: 343 THIPRTKRGVISYSARDIAERLNARALVAFTTSGDTAKRVARLHSHLPLLVFTPNEAVRS 402
Query: 527 QVHLYRGVLPIVYQEPT-ASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-S 584
++ L G + + D +++VD + + + + GD VVV G G +
Sbjct: 403 ELALTWGATTFLCPPVSDTDDMMREVDRALLAMPEYNK-------GDMMVVVAGSPPGVT 455
Query: 585 GFTNTVRVMLV 595
G TN + V L+
Sbjct: 456 GNTNMIHVHLL 466
>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
Epsilonproteobacteria|Rep: Pyruvate kinase -
Nitratiruptor sp. (strain SB155-2)
Length = 458
Score = 297 bits (730), Expect = 4e-79
Identities = 183/486 (37%), Positives = 273/486 (56%), Gaps = 31/486 (6%)
Query: 109 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 168
++ I+ TIGP+S + ++K++ G+NV R+NFSH H+ H +I+ RE K KLG
Sbjct: 1 MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54
Query: 169 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 228
+ AI D GP+IR G ++G +EL KG+ I+L + K D + + Y
Sbjct: 55 T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRLVKT---HPKSKYD-LTLSYPQ 104
Query: 229 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 288
I + ++ G +F DG I +D++T ++N G+L SRKGVN P + L A++
Sbjct: 105 IIDDLEVGEYVFFADGTIRTKVIEKDSDSVTLLVKNPGVLSSRKGVNFPHSNLRLSAITP 164
Query: 289 KDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
KD+ DL FG ++GVD++ SF+ + + + R IL ++ N I++KIE + + NL+ I
Sbjct: 165 KDEKDLRFGAKEGVDIVAISFVNSAQDIKKARSILAQEEANPWIVAKIETKKAVENLESI 224
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
+ SDG+MVARGDLGIE+ EKV + QK +I NR+GKPVI ATQML SMV P PTRA
Sbjct: 225 LQASDGVMVARGDLGIEVGIEKVPVIQKRIIKEANRLGKPVITATQMLLSMVNSPFPTRA 284
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
E+SDVANA++DG+D VMLS ET G YPVE V T+ + E ++ + +
Sbjct: 285 EVSDVANAVIDGSDAVMLSDETTVGKYPVEAVQTLRKVIDETMSIYPFYKRYEG------ 338
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
+D AIV T+SG + ++KYRP PIIAVT +T+ ++
Sbjct: 339 KDVDAIAGSVADLCRSIN---PKAIVSFTSSGTTVKSIAKYRPNAPIIAVTHDKKTSHKL 395
Query: 529 HLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFT 587
L GV V + P +K+ ++ +Q L + F+ GD ++ G G G T
Sbjct: 396 SLVWGV-QTVLEMPK----IKNPEHLIQKFLDTALREEFLFLGDKVIITMGSIVGKEGTT 450
Query: 588 NTVRVM 593
N +RV+
Sbjct: 451 NMIRVV 456
>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
lacusprofundi ATCC 49239
Length = 613
Score = 297 bits (728), Expect = 7e-79
Identities = 188/516 (36%), Positives = 275/516 (53%), Gaps = 32/516 (6%)
Query: 84 TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 142
TV NV S CG + +KS +R + I+CTIGPAS + + + + GM+V R+N S
Sbjct: 5 TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64
Query: 143 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 202
HG+ + E I R + ++ P LA+ +D KGPE+RT L+
Sbjct: 65 HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD------------ 106
Query: 203 ETIKLTTSSD--YQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTC 260
E+I L T S+ + E +A V + PG+ + +DDG I + V +++
Sbjct: 107 ESISLATGSEVTFVEGDDATPERVGLTHSIAAAGPGDTVLLDDGRIECRVERVDGESVVA 166
Query: 261 TIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIR 320
T+ +GG L SRKGVNLPG+ +D+ ++ +D+++L D + ASF+RN ++ I
Sbjct: 167 TVVSGGKLSSRKGVNLPGVAIDVDLITAEDEAELDLAARTNADFVAASFVRNANDVYRIA 226
Query: 321 GILGEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMI 379
L E+G +I I++KIE + NLD II +DG+MVARGDLG+E P E V + QK +I
Sbjct: 227 DALEERGGDDIPIVAKIERAGAVENLDGIIDAADGVMVARGDLGVECPLEDVPVIQKRII 286
Query: 380 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVEC 439
+C G PVI AT+ML+SMV RPTRAE SDVANA+LDG D VMLSGETA GD PV
Sbjct: 287 RKCVNAGVPVITATEMLDSMVSSRRPTRAEASDVANAVLDGTDAVMLSGETAIGDDPVNV 346
Query: 440 VHTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTS 499
V TM I ++ E+ + + V AS +V ++ S
Sbjct: 347 VETMDRIVRQVESSDEYAETREQRVPTAAEG-SRTEALARSARYLARDIGASTVVAVSES 405
Query: 500 GKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGL 559
G +A + +RP P++A T + RQ+ L GV P++ + A D +DN V + L
Sbjct: 406 GFTARKTAMFRPGVPVVATTPSDRVRRQLALSWGVRPVLTE--YAHDMETILDNAVDAAL 463
Query: 560 RFGRQRGFVHPGDNAVVVTGWK---QGSGFTNTVRV 592
G GD VV++G +G+ TNT++V
Sbjct: 464 ----DTGGAASGDTLVVLSGMLTEFEGTNTTNTLKV 495
>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
NBC37-1)
Length = 488
Score = 295 bits (725), Expect = 2e-78
Identities = 178/485 (36%), Positives = 270/485 (55%), Gaps = 25/485 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II TIGPA+ + ++ +M G+N+ R+NFSHG+HEYH+E + R+A + G
Sbjct: 7 IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS--DYQEKGNADTIYVDYKNI 229
I D GP+IR G+LE + LK G+ ++ Y+ K + ++ +I
Sbjct: 64 ---ILQDISGPKIRVGMLE----EDFILKSGDILEFVKEEIVGYKVKEGVYRLCINEPDI 116
Query: 230 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
+ ++ G I++ DG+I + + SAD + IEN GML SRKGVN P + + ++EK
Sbjct: 117 LDQLEVGESIYMYDGIIRAVVKEKSADMVKVEIENNGMLSSRKGVNFPNTHLGINVLTEK 176
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 349
DK D+L+G++ VD + SF+++ + R ++ G ++++++KIE + N+D I+
Sbjct: 177 DKKDILWGIKHEVDFMAISFVQHQKDMTAAREVITSNGGSVQLLAKIEKFDAIENIDAIL 236
Query: 350 AESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAE 409
SDGIMVARGDLGIEIP V L QK +I R N + KPVI ATQML SM K +RAE
Sbjct: 237 EASDGIMVARGDLGIEIPYYDVPLIQKMLIKRANNMSKPVIVATQMLLSMTTKVTASRAE 296
Query: 410 ISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKP 469
ISDVANA+LDGAD VMLS E+A G YP+ V TM + AE ++ + +
Sbjct: 297 ISDVANAVLDGADAVMLSEESAIGHYPIRAVETMVQTIQSAERYYPFQKFSQFDMHDRGD 356
Query: 470 PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
ID C + I+ +T+SG +A ++YRP PI AVT +TA+ +
Sbjct: 357 KID----EAAVRLSGSLNC--AGIIAMTSSGGTAKKAARYRPSQPIYAVTHDKRTAQSLT 410
Query: 530 LYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGFTN 588
L GV+P + + D+ + + + G +RG + D +++TG G G TN
Sbjct: 411 LVWGVVPAFFVAKS------DLRSMIVEVMVQGLKRGILDLDDTYILITGDPVGVPGSTN 464
Query: 589 TVRVM 593
+RV+
Sbjct: 465 LIRVV 469
>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 579
Score = 294 bits (722), Expect = 4e-78
Identities = 175/481 (36%), Positives = 261/481 (54%), Gaps = 21/481 (4%)
Query: 102 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 161
SK + R + I+CT+GP++ ++ K+ E GMNVARMN SHG H H + I + K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159
Query: 162 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 221
Y+A+ ++AI LDTKGPE+R+G L + L G+ T
Sbjct: 160 EYNAQTKDN-TIAIMLDTKGPEVRSGDLP----QPIMLDPGQEFTFTIERGVS---TPSC 211
Query: 222 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPV 281
+ V+Y + N V+ G+ + +D G++S + +S + D++ C + +GG L SR+ +N+ G
Sbjct: 212 VSVNYDDFVNDVEAGDMLLVDGGMMSFMVKSKTKDSVKCEVVDGGELKSRRHLNVRGKSA 271
Query: 282 DLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQG 341
LP+++EKD D+ FGVE VD SF+++ +HE++ L G +I +I KIE+
Sbjct: 272 TLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKKYLQNSGADIHVIVKIESADS 331
Query: 342 MVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVK 401
+ NL II SDG MVARGDLG E+P E+V + Q+ +I C +GK VI A MLESM+
Sbjct: 332 IPNLHSIITASDGAMVARGDLGAELPIEEVPILQEEIINLCRSMGKAVIVAANMLESMIV 391
Query: 402 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFN 461
P PTRAE+SD+A A+ +GAD VMLSGETA G +P++ M + EA I ++
Sbjct: 392 HPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLKAAGVMHTVALRTEATITSGEMPP 451
Query: 462 DLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRH 521
+L K + + L ++ VV T +G A LLS YRP I A T
Sbjct: 452 NLGQAFK---NHMSEMFAYHATMMSNTLGTSTVVFTRTGFMAILLSHYRPSGTIYAFTNE 508
Query: 522 PQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWK 581
+ +++ LY+GV PI Y E T D + + L ++G V G+ +V
Sbjct: 509 KKIQQRLALYQGVCPI-YMEFT-----DDAEETFANALATLLKQGMVKKGEEIAIVQSGT 562
Query: 582 Q 582
Q
Sbjct: 563 Q 563
>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
Pyruvate kinase - Acidobacteria bacterium (strain
Ellin345)
Length = 485
Score = 294 bits (721), Expect = 5e-78
Identities = 166/436 (38%), Positives = 247/436 (56%), Gaps = 14/436 (3%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ TIGPAS + +LE+++ TG++VAR+NFSHG H E I N R A S + G
Sbjct: 10 IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
++A+ D GP++R G ++ + + L+ G+ LTT S G+ + + +
Sbjct: 64 AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDSIV---GDNRRCSMSFAALPQ 117
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VVKPG+R++++DGL+ ++ + + + C + GG L SRKG+NLPGI + + A +E D+
Sbjct: 118 VVKPGDRLYLNDGLVHLLVERIEGTDVHCVVAVGGELRSRKGLNLPGINLGISAFTEHDR 177
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
L F +E GVD + SF++N + +R G + I +KIE + + N DEI+
Sbjct: 178 DCLKFALENGVDAVSQSFVQNAHDIELVRTAAESLGHHPFIFAKIERAEAVQNYDEILRA 237
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
SDGIMVARGDLGIE+P E++ + QK +I+ N GKPVI ATQMLESM+ PTRAE +
Sbjct: 238 SDGIMVARGDLGIEVPMEEIAVIQKQLISGANAAGKPVITATQMLESMITNRLPTRAECT 297
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DVANAI DG DCVMLSGE A G +P E V + I E HR +++ P
Sbjct: 298 DVANAIFDGTDCVMLSGECAVGQFPEEAVAMLGKIAAATEP-HRHRAHPSNVHGAGWTPS 356
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
++A+ V T SG +A ++S+++P I+A++ + R +
Sbjct: 357 TAAQAMGILVERALETAPSAAVFVPTLSGDTARMISRFKPSVWIVALSANENVCRNLKFS 416
Query: 532 RGVLPIVYQEPTASDW 547
GV P+ E A DW
Sbjct: 417 YGVEPVFVGE-EADDW 431
>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
Pyruvate kinase - Rhodopirellula baltica
Length = 476
Score = 293 bits (720), Expect = 7e-78
Identities = 182/494 (36%), Positives = 266/494 (53%), Gaps = 27/494 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + II TIGPA+ + L ++E G++V R+N +HG+ E+ E + R+ K S +
Sbjct: 5 RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISRHV 64
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS--SDYQ--EKGNADTIY 223
A+ +D KGPEIRTG +E +ELK G+ + L T +D E +
Sbjct: 65 ------AVMMDVKGPEIRTGAVEDA----IELKAGDELVLFTEDCADQSAVESDGTPRVS 114
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 283
V+Y + + + I +D GL+ A T+ C + G+L SR+ +NLPG+ V+L
Sbjct: 115 VNYLGLPGAIDLDSTILVDSGLLHWHVLKKDATTVRCRVITPGVLESRRHINLPGVQVNL 174
Query: 284 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMV 343
PA+++KD++DL GV+ G+D + SF+R + +R L E G +IISKIE+ G+
Sbjct: 175 PAITDKDRTDLAAGVKAGIDFVALSFVRQAEDVRTLRAFLDEHGSPARIISKIEDQAGVR 234
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
N+ II +SD IMVARGDLG+EI ++ L Q +I C GKPVI AT +LESM++ P
Sbjct: 235 NMKAIIRQSDAIMVARGDLGVEIDYHRLPLVQTDLIRACQEDGKPVIIATHLLESMIQSP 294
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
PTRAE+SDV+NAI + AD VMLSGET G YP+E V + NI E + RQL + +
Sbjct: 295 VPTRAEVSDVSNAIREQADAVMLSGETTTGKYPLESVGVLQNIVASIEPTV-SRQLNSKI 353
Query: 464 VSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPR-CPIIAVTRHP 522
V +P + S IVV T SG A++L RPR PI A T
Sbjct: 354 VLR-----EPKSMMLRSACTLAQEMGDSGIVVFTRSGFLAYVLGALRPRGVPIFAFTDVE 408
Query: 523 QTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ 582
T R + L GV EP ++ +D D + + L ++ G+ PG V+T
Sbjct: 409 HTFRHLMLPWGV------EPFFMEFSEDHDQTITNALEVLKESGWCKPGVWLGVITNALA 462
Query: 583 GSGFTNTVRVMLVQ 596
+T+++ VQ
Sbjct: 463 DEKIIDTLQLRQVQ 476
>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
proteobacterium MLMS-1
Length = 493
Score = 293 bits (720), Expect = 7e-78
Identities = 173/496 (34%), Positives = 269/496 (54%), Gaps = 26/496 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGPA+ + + ++ E GMNVAR+N SHGS E+H I N + K Y+
Sbjct: 16 RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
SLA+ LDT+G EIR+G L+ ++EL+ G+ + LTT Q + + V +
Sbjct: 74 ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTTRR--QAELEPGCVEVSHD 123
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
V PG+ I +D G++ + V + C + G+LGSR+ +N+ G DLPA++
Sbjct: 124 GFVAEVTPGDIILVDGGMLRLKVVEVGRTDVRCQSLDEGVLGSRRHLNIRGKSADLPAIT 183
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
E+D +D+ FG+EQ VD I SF+R + ++ L +G +++++KIE+ + LD
Sbjct: 184 EQDWADIEFGMEQRVDFIALSFVRTAEPIQVVQQHLAARGVTMEVMAKIESAASIAQLDA 243
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
IIA +DG+MVARGDLG E+P E+V L Q ++A+C R GKPV+ AT MLESM+ P PTR
Sbjct: 244 IIAAADGVMVARGDLGAELPYEEVPLLQDEIVAKCRRAGKPVVVATHMLESMIVNPTPTR 303
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHR--QLFNDLVS 465
AE++D+ +A+ G+D +MLSGETA G YP + + M + + E + Q
Sbjct: 304 AEVTDITHAVQQGSDAIMLSGETATGRYPYKALEVMDAVARRIERHQEQQGGQAGFGCAC 363
Query: 466 EV------KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVT 519
++ + A+ +VIT G A LLS RP PI+A T
Sbjct: 364 QLGRQGGGSDRLHAKMEISRSAAILGNNLGAAGTLVITRRGLMAALLSNCRPTAPILAFT 423
Query: 520 RHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
R++ +Y GV V + + D + +Q + +++G VH G +V++
Sbjct: 424 NTTHVRRRLGIYWGVQAFVVKLSS------DPEVSIQRAVEQLQRKGIVHRGQRIIVLSD 477
Query: 580 WKQGSGFTNTVRVMLV 595
G F TV+V ++
Sbjct: 478 ILAGGLFVETVQVRVI 493
>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
Pyruvate kinase - Mycobacterium tuberculosis
Length = 472
Score = 293 bits (718), Expect = 1e-77
Identities = 168/487 (34%), Positives = 261/487 (53%), Gaps = 27/487 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R I+CT+GPA++ ++ ++E GM+VARMNFSHG ++ H R A + +
Sbjct: 3 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G + D +GP+IR G G + E GET+++T + +G+ D + YK
Sbjct: 63 G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 110
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ G+R+ +DDG ++++ +V D + CT+ GG + KG++LPG+ V PA+S
Sbjct: 111 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 170
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD DL F + GVDM+ SF+R+ A + + ++ G+ + +I+K+E + + NL+
Sbjct: 171 EKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEA 230
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ D +MVARGDLG+E+P E+V L QK I KPVI ATQML+SM++ RPTR
Sbjct: 231 IVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTR 290
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVANA+LDGAD +MLSGET+ G YP+ V TM+ I E ++ +
Sbjct: 291 AEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVE----ENSTAAPPLTHI 346
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
P + A A+V T SG + L++ P++A T P+ Q
Sbjct: 347 --PRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEVRSQ 404
Query: 528 VHLYRGVLPIVYQEPTASD-WLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGS-G 585
+ + G + + ++D ++ VD + R+ R GD V+V G G+ G
Sbjct: 405 LAMTWGTETFIVPKMQSTDGMIRQVDKSLLELARYKR-------GDLVVIVAGAPPGTVG 457
Query: 586 FTNTVRV 592
TN + V
Sbjct: 458 STNLIHV 464
>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
Pyruvate kinase - Parabacteroides distasonis (strain
ATCC 8503 / DSM 20701 / NCTC11152)
Length = 485
Score = 292 bits (717), Expect = 2e-77
Identities = 163/424 (38%), Positives = 247/424 (58%), Gaps = 18/424 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+ +VA +E + + GMNV R+N +H E + N R + S ++G
Sbjct: 7 IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
I +DTKGPE+RT + K GE +K+ + D QE + D I V YKN N
Sbjct: 60 ---ILMDTKGPEVRTTTTVN--KEPIPFKTGEIVKVIGNPD-QETSH-DCICVSYKNFVN 112
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ G+ I IDDG + + S D L C I+N LGSRK VN+PG+ ++LP+++EKD+
Sbjct: 113 DLAIGSDILIDDGDLEMKVTGKSGDCLLCEIQNDATLGSRKSVNVPGVRINLPSLTEKDR 172
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+++L+ ++ +D I SF+RN + +I+ IL E+ IKII+KIEN +G+ N++EI+
Sbjct: 173 NNILWAIDHDLDFIAHSFVRNKQDVLDIQRILDERNSPIKIIAKIENQEGVDNIEEILEV 232
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+ G+M+ARGDLGIE+P EK+ Q+ +I +C V KPVI ATQML SM+ PRPTRAE++
Sbjct: 233 AYGVMIARGDLGIEVPAEKIPGIQRMLIRKCVEVKKPVIVATQMLHSMINNPRPTRAEVT 292
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK-PP 470
D+ANAI D +MLSGETA G YP+E V TM + +EAE + ND+ ++
Sbjct: 293 DIANAIYYRTDALMLSGETAYGKYPIEAVQTMTKVAREAEKT---KLSANDIRVPIEGND 349
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+D +K AI+ + +G++A L+ +R + A+ +P+ R + L
Sbjct: 350 LDVTSFLAKQAVKSSSKLHVKAIITDSYTGRTARYLAAFRGTSTVFAICYNPRVMRMLGL 409
Query: 531 YRGV 534
GV
Sbjct: 410 SYGV 413
>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
Pyruvate kinase - Monocercomonoides sp. PA203
Length = 516
Score = 291 bits (715), Expect = 3e-77
Identities = 181/504 (35%), Positives = 268/504 (53%), Gaps = 30/504 (5%)
Query: 104 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 163
+S+ L+ I+ T+GPA+ + +++ G+NV RMNFSHG+HE+H + + R+ +
Sbjct: 32 ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90
Query: 164 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 223
LG +AI D +GP++RT GG ++ +K+G+ + + S + + G T +
Sbjct: 91 ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPEPGKPGVITTKF 142
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVD- 282
NV +P + IDDGLI +I Q + + L C +E GG + KG+NLP +
Sbjct: 143 TPMITHCNVGEP---VLIDDGLIRLIVQEKNPNELVCLVEQGGDVKDHKGINLPATDLGP 199
Query: 283 LPAVSEKDKSDLLFGVEQ-GVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQG 341
LPA++EKD D F ++ VD SF+R + ++R ++ KGK ++II KIE +
Sbjct: 200 LPALTEKDIEDAKFVLDTLEVDFFALSFVRKPQDVLDLRHLIEAKGKEMRIIVKIEKPEA 259
Query: 342 MVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVK 401
+ NLDEI+A SD MVARGDL +E+ KV QK +I C +G PVI ATQMLESM
Sbjct: 260 IKNLDEILAVSDACMVARGDLAVEVGTAKVPCLQKHIIRHCLEMGLPVITATQMLESMTH 319
Query: 402 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVI------- 454
P PTRAE +DVANAI DG DCVMLSGETA G++PVE VHTM +I E E +
Sbjct: 320 NPTPTRAEATDVANAIYDGTDCVMLSGETAAGEFPVETVHTMQDIILETEFHLRDGKRSQ 379
Query: 455 WHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCP 514
+ +LFN + A A ++ +G +A LS RP P
Sbjct: 380 FEAELFNPEKQKDSSGKTSGFSVGLAAHMLARSTDAVAFGCVSDTGNAAIRLSTSRPAIP 439
Query: 515 IIAVTRHPQTARQVHLYRGVLPIVYQE-PTASDWLKDVDNRVQSGLRFGRQRGFVHPGDN 573
I + T R++ L RG ++ P A + +++ ++ ++ GF+ G+N
Sbjct: 440 IYVFSSSLSTIRRMCLTRGAYGLMMSSIPPAEEIFSEMEKKM-------KRMGFIKTGEN 492
Query: 574 AVVVTGWKQ-GSGFTNTVRVMLVQ 596
V G TNTV V V+
Sbjct: 493 VVYTAGLPTLAHATTNTVHVKTVE 516
>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
isozyme G, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 562
Score = 291 bits (715), Expect = 3e-77
Identities = 176/509 (34%), Positives = 273/509 (53%), Gaps = 31/509 (6%)
Query: 97 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 153
G + +S Y+ R + I+CTIGP++ + ++ K+ E GMNVAR+N SHG H H TI
Sbjct: 77 GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136
Query: 154 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 213
+E + K+ +AI LDTKGPE+ + G + LK+G+ +
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEV----ISGDVPKPILLKEGQEFNFSIKRGV 187
Query: 214 QEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKG 273
+ DT+ V+Y + N V+ G+ + +D G++S+ +S ++D + C + +GG L SR+
Sbjct: 188 STE---DTVSVNYDDFINDVEAGDILLVDGGMMSLAVKSKTSDIVKCEVIDGGELKSRRH 244
Query: 274 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKII 333
+N+ G LP+++EKD D+ FGV VD SF+++ +HE++ L +I +I
Sbjct: 245 LNVRGKSATLPSITEKDWDDIKFGVNNQVDFYAVSFVKDAKVVHELKDYLKSCNADIHVI 304
Query: 334 SKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICAT 393
KIE+ + NL II+ SDG MVARGDLG E+P E+V L Q+ +I RC + KPVI AT
Sbjct: 305 VKIESADSIPNLHSIISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCQSMQKPVIVAT 364
Query: 394 QMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAV 453
MLESM+ P PTRAE+SD++ A+ +GAD VMLSGETA G YP++ V M + E+
Sbjct: 365 NMLESMIDHPTPTRAEVSDISIAVREGADAVMLSGETAHGKYPLKAVKVMHIVALRTESS 424
Query: 454 IWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRC 513
+ Q S+ L++ I+V T +G A +LS RP
Sbjct: 425 L---QKSTSSPSQSAAYKSHMGEMFAFHSSSMANTLSTPIIVFTRTGSMAIILSHNRPSS 481
Query: 514 PIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDN 573
+ A T + + +++ LY GV+PI Y E + D + ++ + V G
Sbjct: 482 TVFAFTNNERVKQRLALYHGVVPI-YME-----FSSDAEETFSRAIKLLLSKSLVKDGQY 535
Query: 574 AVVVTG-----WKQGSGFTNTVRVMLVQS 597
+V W++ S T+ ++V VQS
Sbjct: 536 VTLVQSGAQPIWRRHS--THHIQVRKVQS 562
>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
Pyruvate kinase - Bacteroides fragilis
Length = 485
Score = 288 bits (707), Expect = 3e-76
Identities = 173/496 (34%), Positives = 271/496 (54%), Gaps = 27/496 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
++ + I+ +I +V ++++ + GMNV RMN +H S E I N R
Sbjct: 3 LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSNR---- 58
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+AI +DTKGPE+RT + + + GE +K+ D + + I V Y
Sbjct: 59 ------IAILMDTKGPEVRTT----ANADPILYQIGEKVKIVGDPDRET--TRECIAVSY 106
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
N + + G I IDDG + + + + L C ++N LGSRK VN+PG+ ++LP++
Sbjct: 107 PNFVHDLNVGGTILIDDGDLELRVIDKTTEYLLCEVQNEATLGSRKSVNVPGVRINLPSL 166
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+EKD++++L+ +E+ +D I SF+RN + +IRGIL +I+II+KIEN +G+ N+D
Sbjct: 167 TEKDRNNILYAIEKDIDFIAHSFVRNRQDVLDIRGILDAHNSDIRIIAKIENQEGVDNID 226
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI+ +DG+MVARGDLGIE+P E++ Q+ +I +C KPVI ATQML +M+ PRPT
Sbjct: 227 EILEVADGVMVARGDLGIEVPQERIPGIQRMLIRKCILAKKPVIVATQMLHTMINNPRPT 286
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL-VS 465
RAE++D+ANAI D +MLSGETA G YPVE V TM I +AE + ND+ +
Sbjct: 287 RAEVTDIANAIYYRTDALMLSGETAYGKYPVEAVKTMTKIAAQAEK---DKLEENDIRIP 343
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
+ D TK AI+ + G++A L+ +R + P++A+ +T
Sbjct: 344 LDENSNDVTAFLAKQAVKATTKLKIRAIITDSYQGRTARNLAAFRGKYPVLAICYKEKTM 403
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSG 585
R + L GV I E L + + LR + G +HP D ++ K G+
Sbjct: 404 RHLALSYGVEAIYMPE------LANGQEYYFAALRRLLKEGRLHPTDMVGYLSSGKAGTQ 457
Query: 586 FTNTVRVMLVQSASMH 601
T+ + + +V+ A H
Sbjct: 458 -TSFLEINVVEDALKH 472
>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 621
Score = 286 bits (702), Expect = 1e-75
Identities = 174/475 (36%), Positives = 259/475 (54%), Gaps = 37/475 (7%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CTIGP++ + ++ K+ ETGMNVAR+N SHG H H +TI +E + K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
+AI LDTKGPE+R+G + + LK+G+ T + +T+ V+Y
Sbjct: 226 -----IAIMLDTKGPEVRSGDVP----KPIMLKEGQEFNFTIKRGVSSE---NTVSVNYD 273
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ N V+ G+ + +D G++S+ +S S D + C + +GG L SR+ +N+ G LP+++
Sbjct: 274 DFVNDVEVGDILLVDGGMMSLAVKSKSKDLVKCQVIDGGELKSRRHLNVRGKSATLPSIT 333
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
+KD D+ FGV+ VD SF+++ +HE++ L G +I +I KIE+ + NL
Sbjct: 334 DKDWEDIKFGVDNQVDFYAVSFVKDAEVVHELKDYLRSCGADIHVIVKIESADSIPNLHS 393
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
II+ SDG MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+ P PTR
Sbjct: 394 IISASDGAMVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMINHPTPTR 453
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE+SD+A A+ +GAD VMLSGETA G+ H + N E I H+ L
Sbjct: 454 AEVSDIAIAVREGADAVMLSGETAHGN-----THEIPN----KEKTICHKIL-------- 496
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
+ L + I+V T +G A LS YRP I A T + ++
Sbjct: 497 --ALSHMGTMFAFHATTMANTLNTPIIVFTRTGSMAITLSHYRPFSTIFAFTNEERVKQR 554
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ 582
+ LY GV+PI Q SD D + L +G + G++ +V Q
Sbjct: 555 LVLYHGVMPIFMQ---FSD---DAEETFSRALSILVNKGLMKEGEHVTLVQSGAQ 603
>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
Pyruvate kinase - Methylobacterium extorquens
(Protomonas extorquens)
Length = 483
Score = 286 bits (702), Expect = 1e-75
Identities = 178/492 (36%), Positives = 271/492 (55%), Gaps = 30/492 (6%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPAS ++EK+ G +V R+N SH + E E I R E+ +
Sbjct: 10 RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G I +D +GP++R G G + L+ G+T L SD G+ D +++ +
Sbjct: 70 G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVL--DSD-PTPGDTDRVFLPHP 117
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
I + ++P + I IDDG + +I VS +E GG + +RKGV+LP + +PA++
Sbjct: 118 EILSALEPSHGILIDDGKLRLIVTEVSEGRAVTRVEVGGRISNRKGVSLPHTALPVPAMT 177
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
EKD+ DL G+ G D I SF++ + E++ + G+ + +++KIE Q + LDE
Sbjct: 178 EKDRGDLEAGLAAGADWIAVSFVQRPEDVAEVKKVAA--GRAL-VMAKIEKPQALTRLDE 234
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
II SDGIMVARGDLG+E+P E+V QK + R+GKPV+ ATQMLESM+ P PTR
Sbjct: 235 IIEISDGIMVARGDLGVEMPLEQVPGVQKRITRVARRLGKPVVVATQMLESMITSPVPTR 294
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE--AVIWHRQLFNDLVS 465
AE+SDVA A+ +GAD VMLS E+A GD+PVE + TM I ++ E A+ W + L++
Sbjct: 295 AEVSDVATAVYEGADAVMLSAESAAGDFPVEAIGTMNRIAEQVERDALYW-----SILMA 349
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLA-SAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQT 524
+ P + L+ +I+ T SG + L++ RP +IA+T +T
Sbjct: 350 QRSEPEPTASDAIAAAAHQIVEALSLRSIMAWTHSGSTVLRLARARPNASVIALTPKRET 409
Query: 525 ARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG- 583
AR++ + GV PIV ++ + DVD+ +F + F GD ++V G G
Sbjct: 410 ARRLTMAWGVHPIVTKDAS------DVDDMAFRAAKFAVRERFAEIGDRVIIVAGVPFGI 463
Query: 584 SGFTNTVRVMLV 595
G TN VR+ V
Sbjct: 464 PGATNMVRIAFV 475
>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
Length = 507
Score = 285 bits (700), Expect = 2e-75
Identities = 172/494 (34%), Positives = 263/494 (53%), Gaps = 26/494 (5%)
Query: 101 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 160
++K R + I+ T+GPAS + + + + G +V R+NFSHGSHE H + R E
Sbjct: 13 NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72
Query: 161 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 220
A+ G P + I D +GP++R G G V LK G+ L G+
Sbjct: 73 ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVLDRDPT---PGDVT 120
Query: 221 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIP 280
+++ + + PG + +DDG I + ++ + + +GG L RKGVN+P
Sbjct: 121 RVHLPHPELYAATAPGQSLLLDDGKIRLAVEAADPTAIVTRVVDGGPLSDRKGVNVPDAV 180
Query: 281 VDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ 340
+ +PA++EKD DL F + GVD I SF++ + R I+G++ ++SKIE
Sbjct: 181 IPIPALTEKDLRDLDFALSLGVDWIALSFVQRAEDVIAAREIIGDRAG---LLSKIEKPA 237
Query: 341 GMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 400
+++L++I+ SD +MVARGDLG+E+PPE+V QK ++ + GKPV+ ATQMLESM+
Sbjct: 238 ALLHLEDIVQASDALMVARGDLGVELPPERVPGVQKRILRMARQHGKPVVVATQMLESMI 297
Query: 401 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 460
+ P PTRAE SDVA+A+ DG D VMLS E+A G +PV V M I E E +R L
Sbjct: 298 EAPVPTRAEASDVASAVYDGTDAVMLSAESASGKHPVAAVSIMNRIIAETERDPLYRNLI 357
Query: 461 NDLVSEVKPPIDPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVT 519
+ ++ +PP+ T L A A V T+SGK++ ++ RP PI+++T
Sbjct: 358 D---AQHQPPLPTRQDAICAALRDVTHILGAVATVTYTSSGKTSLRAARERPLAPIVSIT 414
Query: 520 RHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
TAR++ + GV T S + +VD V + R + GF GD + G
Sbjct: 415 PRLDTARRLAITWGV------HSTVSPDVSNVDEMVDAACRAAAREGFAVSGDQIAITAG 468
Query: 580 WKQG-SGFTNTVRV 592
G +G TN +R+
Sbjct: 469 MPFGQAGSTNLLRL 482
>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
Length = 519
Score = 285 bits (699), Expect = 2e-75
Identities = 151/343 (44%), Positives = 220/343 (64%), Gaps = 19/343 (5%)
Query: 109 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 168
L+ I+CTIGP + + ++++++ GM++AR+NFSHGS E H E IRN R++ G
Sbjct: 96 LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRDSRS------G 149
Query: 169 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 228
+ ++IALDT+GPE+R E +++++ GE ++ + S ++ VD K+
Sbjct: 150 AGRHVSIALDTRGPEVRLRTPE---MKDIKVEGGEVLRFSLLSSEKDIWIPG---VDLKS 203
Query: 229 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 288
+ NR+FIDDG I + +V D C + N GM+ S K +N PG + A+ +
Sbjct: 204 LG----VDNRVFIDDGAIELRVVNVEEDGFECEVLNSGMIKSNKSMNFPGTDIGDRALGD 259
Query: 289 KDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
+DK+D+ FG+E G+DM+FASF+ A + EIR ++G K + ++SKIE+ GM NL EI
Sbjct: 260 EDKNDIAFGLENGIDMVFASFVSCRADVEEIRRLVGSK---VPVVSKIESCLGMRNLKEI 316
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
SDG+M+ARGDLG+EI E +F AQK ++ R G+PVICATQM+ESM K P R+
Sbjct: 317 ALCSDGVMIARGDLGVEIGLENMFSAQKRILYEVKREGRPVICATQMMESMTLKNAPNRS 376
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
EISDV NA+LDG DCVMLS E+A G +PVE V M +IC +AE
Sbjct: 377 EISDVGNAVLDGCDCVMLSAESAVGMFPVETVKFMRSICADAE 419
>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
smegmatis str. MC2 155|Rep: Pyruvate kinase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 477
Score = 284 bits (697), Expect = 4e-75
Identities = 172/492 (34%), Positives = 261/492 (53%), Gaps = 21/492 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CT+GPA+ +VL ++++ GM+VAR+NFSH +H H+ RE +
Sbjct: 4 RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G + D +GP+IR G G V GE + +TT G+ D + Y
Sbjct: 64 G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITTEDC---PGDHDRVSTTYA 111
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ V+ G+R+ +DDG + + +V + C + +GG + KG++LP IPV +P +S
Sbjct: 112 GLSQDVRAGDRLLVDDGRVDLRVVAVDGPDIRCEVVDGGPVSDHKGISLPNIPVSVPPLS 171
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
+KD DL F +E G DMI SF+R + I+ E G+ + +I+K+E + + +L
Sbjct: 172 DKDIEDLKFALELGADMIAMSFVRAPEEVELAHKIMDEVGRRVPVIAKLEKPEAVSDLPA 231
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ DG+MVARGDLG+E+P E++ L Q+ IA C + KPVI ATQML+SMV RPTR
Sbjct: 232 IVEAFDGLMVARGDLGVEMPLEQIPLVQRRAIALCRQAAKPVIVATQMLDSMVSDRRPTR 291
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE+SDVANA+ D AD VMLS ET+ G P V TMA I AE+ + + E
Sbjct: 292 AEVSDVANAVFDRADAVMLSAETSVGADPAHAVATMARIVVAAESGSGRGETPESALVEA 351
Query: 468 KPPIDPXXXXXXXXXX--XXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
D + A+A+ T +G +A L++ R P++A +
Sbjct: 352 VNGTDAVFGDAIAVAACEVGRRLGAAALCCFTRTGDTALRLARQRSPLPLLAFAHDDEVR 411
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-S 584
++ GV V PT + + + V L G HPGD VVV+G + G +
Sbjct: 412 GRLTFSWGVESAVL-APT--ELAESMPGEVSRAL---LSMGACHPGDVVVVVSGSRSGVA 465
Query: 585 GFTNTVRVMLVQ 596
G+T++VRV+ V+
Sbjct: 466 GYTDSVRVLRVE 477
>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7070-PB, isoform B - Tribolium castaneum
Length = 535
Score = 282 bits (692), Expect = 2e-74
Identities = 159/502 (31%), Positives = 276/502 (54%), Gaps = 25/502 (4%)
Query: 92 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 151
L+H+ L S+ RL+ I P ++ +E+ ++ GM VA + + + + E
Sbjct: 44 LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102
Query: 152 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 211
+ R + K+G + +AI LD EI+TG L E+EL+KG+T K+
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLLKP-LKEIELEKGQTTKIVAKP 161
Query: 212 DYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSR 271
++ + + + IYV+Y+NI +VVKPG+ + I D I + V+ D + C IE G+L
Sbjct: 162 EFANRVSKEFIYVNYENIADVVKPGDSLIIGDDNIRMSAIEVARDIINCIIEKAGLLTDN 221
Query: 272 KGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK 331
V LP +P+ LP +K + + +D++F + L ++ LG +
Sbjct: 222 LSVKLPNVPITLPKTESHEKL-IQIKEKCEIDIVFVG----PSKLDMVKETLGP---TVL 273
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
II+K+E + D ++ +SDG+++ G+ + E+VFL QK++IA CN++GKPV+
Sbjct: 274 IIAKLEYASSVDFFDSLVKKSDGVIID-GEKLMATSKERVFLVQKSVIANCNKLGKPVLA 332
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
A + T++ ++D+AN ++DG D ++L + + + +++ ICK AE
Sbjct: 333 A-------INCHAVTKSIVNDIANTVIDGIDGLLLPPDP-------DLIESISLICKAAE 378
Query: 452 AVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRP 511
++ ++LF+DLVS PPI+P K A+AI++ITT+G+SA L+S +RP
Sbjct: 379 GAVYQKRLFDDLVSLKPPPIEPIISIAISAVEASFKSNAAAIILITTTGRSAKLISSFRP 438
Query: 512 RCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPG 571
RCP+IA+TR + A+Q+ +Y+GV+PI Y + T + ++V+ +Q G+ FG+ G++ G
Sbjct: 439 RCPVIALTRFGRIAKQLMIYKGVIPIFYVQKTGDTFKENVEKSIQLGMTFGKVNGYIRMG 498
Query: 572 DNAVVVTGWKQGSGFTNTVRVM 593
D VVV G + GF N + V+
Sbjct: 499 DAVVVVFGTRNNVGFKNCMEVV 520
>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
MC-1)
Length = 569
Score = 281 bits (688), Expect = 5e-74
Identities = 171/500 (34%), Positives = 265/500 (53%), Gaps = 25/500 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPA +V + +++E G++VAR+N SHG H+ H E I N REA + ++
Sbjct: 3 RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREASRIAKREV 62
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDY 226
A+ D +GP+IR G L+ + L+KG+ + + K D I Y
Sbjct: 63 ------ALLCDLQGPKIRVGHLD----EPLRLEKGQQWAIIPEGSHPPKLKCDGIIPCTY 112
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ PG RI DDG + L IE+GG+L S KG+N+P + P++
Sbjct: 113 AGLAKDAVPGCRILFDDGYLQARAIGTEEGALLVNIEHGGLLKSHKGINMPDASISAPSL 172
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+ KD+ DL FGV+ VD + SF+R+ + ++ +L + II+KIE + + N+D
Sbjct: 173 TTKDQQDLFFGVKHDVDYVALSFVRSAKCVQNVKFMLHRRKIYKPIIAKIERPEAIRNID 232
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EII DGIM+ARGD+ +EI +V Q+ +I +C GKPVI ATQMLESM++ P PT
Sbjct: 233 EIIKVVDGIMIARGDMAVEIGNHRVPSVQRQIIQKCRAKGKPVITATQMLESMIQNPSPT 292
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVANAI DG D VMLS ET+ G P+ V TM I +EAE +L D S
Sbjct: 293 RAEASDVANAIWDGTDAVMLSAETSVGVDPINTVLTMGRIVEEAERNPRGPRL--DAESH 350
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
+ A I+ +T +G SA L+++RP P++ R R
Sbjct: 351 -----SISSASMMAAARVAEQVSARWIIALTVTGSSALSLARFRPEVPVLGAARTQGGVR 405
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVT--GWKQGS 584
+++LY G+ P ++ + + +D++ V +++ R++ + G+ VVV G
Sbjct: 406 RMNLYWGITPRLFN--YSIEEREDIEPEV---IQWMREQSMLQVGEKIVVVKGGGLLSNH 460
Query: 585 GFTNTVRVMLVQSASMHTDG 604
++++RV LV+ +G
Sbjct: 461 STSSSIRVDLVRDTRNIDEG 480
>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 1010
Score = 279 bits (685), Expect = 1e-73
Identities = 143/271 (52%), Positives = 185/271 (68%), Gaps = 3/271 (1%)
Query: 274 VNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE--KGKNIK 331
+N G+ DL A++E+DK DL FG +Q VDMIFASFIR+ AL EIR LG ++IK
Sbjct: 259 INPQGVAADLNAITEQDKLDLKFGADQKVDMIFASFIRDAKALKEIRQALGACPSSEHIK 318
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
IISKIE+ Q + N+DEII ESDGIMVA G++G EI E V LAQK+++A+CN+VGKPVIC
Sbjct: 319 IISKIESQQALANIDEIIRESDGIMVALGNMGNEIALEAVPLAQKSIVAKCNKVGKPVIC 378
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
A QM+ SM+ KPRPTRAE SDVANAILDG D ++LS ETAKG YPV+CV MA IC + E
Sbjct: 379 ANQMMNSMITKPRPTRAESSDVANAILDGCDALVLSDETAKGKYPVQCVQCMARICAKVE 438
Query: 452 AVIWHRQLFNDLVSEVK-PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYR 510
+V+W+ + N+L SEV+ D T A AIVV + + ++S+ R
Sbjct: 439 SVLWYESIQNNLKSEVRINAADHISAVSTAIAEAATVSQAQAIVVASPCSIVSQMVSQMR 498
Query: 511 PRCPIIAVTRHPQTARQVHLYRGVLPIVYQE 541
P CPI+ +T P A Q L+RGV P++ +E
Sbjct: 499 PPCPIVLLTGCPHEAAQSLLFRGVYPLLVKE 529
Score = 85.0 bits (201), Expect = 5e-15
Identities = 42/95 (44%), Positives = 59/95 (62%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
SQL + L + + + L+ IICTIGP+S VL ++ GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 184
+ I+ R+A Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259
>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
Length = 477
Score = 279 bits (684), Expect = 2e-73
Identities = 160/431 (37%), Positives = 240/431 (55%), Gaps = 17/431 (3%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CTIGPAS+ V L KM+E GMN+AR+NF+HGS E H + N R+A K
Sbjct: 11 IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ I D GP+IR G ++ +E+KKG+ + L+ EK I +++K+ +
Sbjct: 65 DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS------EKPQEGVIPINFKDFSK 113
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VK G+ I+++DG + ++ + V D + + G + S KGVNLP + + + A+ + +K
Sbjct: 114 YVKVGDSIYMNDGFVELMVEKVEDDKVYAVSLSAGKISSHKGVNLPNVDLPVRAIGDYEK 173
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ F + +D I SF+++ + + + + II+KIE Q + N+DEI+
Sbjct: 174 RCIDFAKKIDMDAISVSFVKDQRDVIDAKEYCNTIDYHPFIIAKIERPQALKNIDEILEA 233
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
SDGIMVARGDLGIE P E + +AQK +I + N GKPVI ATQMLESM++ PRPTRAE S
Sbjct: 234 SDGIMVARGDLGIETPIECIAMAQKHIIKKANLAGKPVITATQMLESMIESPRPTRAEAS 293
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DVANAILDG DC+M+S E+A G +P V T+ANI E ++ + E+
Sbjct: 294 DVANAILDGTDCIMVSEESAIGKHPDLVVSTLANIAACVEKEFDKNPIYKAFLQELSTLN 353
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
AS ++V TTSG +A +SK++ ++ +TR + + +
Sbjct: 354 TLEDIMAYNAFNMAKHINASLVIVPTTSGTTARRMSKFKLPVWVLGITRDERVKKHLGFS 413
Query: 532 RGVLPIVYQEP 542
GV Q P
Sbjct: 414 YGVFGFYDQNP 424
>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
Pyruvate kinase - Flavobacteriales bacterium HTCC2170
Length = 480
Score = 278 bits (682), Expect = 3e-73
Identities = 167/501 (33%), Positives = 276/501 (55%), Gaps = 33/501 (6%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
I+ + I+ T+GPA+ V+ M++ G++V R+NFSH +E ++ RE + +
Sbjct: 4 IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
++AI D +GP++R G++ G EV + G+ I T ++ GN++ +Y++Y
Sbjct: 63 -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPFE--GNSERVYMNY 111
Query: 227 KNITNVVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
V PG RI +DDG L+ + + D + + GG L S+KGVNLP + LPA
Sbjct: 112 AAFPKDVNPGERILLDDGKLMFEVVSTNKKDKVRAKVIQGGPLKSKKGVNLPNTNISLPA 171
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN-IKIISKIENHQGMVN 344
++EKD D F + VD I SF+R+ + +++ I+ E ++ I II+KIE + + N
Sbjct: 172 LTEKDVKDAKFAISLDVDWIALSFVRHSQDIIDLQNIIKEHAEHKIPIIAKIEKPEAVEN 231
Query: 345 LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPR 404
+D+I++ DG+MVARGDLG+E+P +V L QK ++ R + PVI ATQM+E+M+
Sbjct: 232 IDKIVSYCDGLMVARGDLGVEVPAHEVPLIQKKLVLRAKKARIPVIIATQMMETMITSLT 291
Query: 405 PTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLV 464
PTRAE++DVAN+++DGAD VMLSGET+ G+YPV+ + MA+I + E + L V
Sbjct: 292 PTRAEVNDVANSVMDGADAVMLSGETSVGNYPVQVIEKMASILESVE----NSDLIT--V 345
Query: 465 SEVKPPIDPXXXXXXX----XXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTR 520
+ P I + A AI +T SG +A +S +RP I+ T
Sbjct: 346 PQEPPHIRTNRYITKSVCYHAATMANEIKAKAISTLTNSGYTAFQISAWRPSAHILVFTS 405
Query: 521 HPQTARQVHLYRGVLPIVYQEPTASD-WLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
+ + Q++L GV Y + ++D ++DV+ ++GF+ GD + +
Sbjct: 406 NKRILTQLNLLWGVKAFYYDKYVSTDETIEDVNG-------IACKKGFLDVGDMLISLAA 458
Query: 580 WK-QGSGFTNTVRVMLVQSAS 599
+ G NT+RV +++ +
Sbjct: 459 MPIKDKGMVNTLRVTEIETCT 479
>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
Pyruvate kinase - Thermotoga maritima
Length = 466
Score = 274 bits (672), Expect = 5e-72
Identities = 167/489 (34%), Positives = 268/489 (54%), Gaps = 24/489 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CT+GP + + ++EKM++ G+NV R+N SHG + I ++ + K
Sbjct: 1 MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
P +AI +D GP+IRTG LE VELK+G+ LTT + GN + V+
Sbjct: 57 KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTTK---EILGNEHIVSVNL 108
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
++ VK G+ I + DG I + + + ++ GG + R+GVN+P + + ++
Sbjct: 109 SSLPKDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPTADLSVESI 168
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+++D+ + G V+ SF+R + + + + + GK I +ISKIE + + L+
Sbjct: 169 TDRDREFIKLGTLHDVEFFALSFVRKPEDVLKAKEEIRKHGKEIPVISKIETKKALERLE 228
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EII SDGIMVARGDLG+EIP E+V + QK +I KPVI ATQ+LESM++ P PT
Sbjct: 229 EIIKVSDGIMVARGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPT 288
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE++D+ANAI DGAD ++L+ ETA G +P+E + ++ + KEAE + + F + +
Sbjct: 289 RAEVTDIANAIFDGADALLLTAETAVGKHPLEAIKVLSKVAKEAEKKL---EFFRTIEYD 345
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
D A I+ T SG +A +SKY PI+A+T +T
Sbjct: 346 TS---DISEAISHACWQLSESLNAKLIITPTISGSTAVRVSKYNVSQPIVALTPEEKTYY 402
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGF 586
++ L R V+P++ ++ S L+ ++ GL+ + G GD V+ +G G
Sbjct: 403 RLSLVRKVIPVLAEK--CSQELE----FIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGT 456
Query: 587 TNTVRVMLV 595
TNT+RV+ V
Sbjct: 457 TNTIRVLKV 465
>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
group|Rep: Pyruvate kinase - Bacillus anthracis
Length = 352
Score = 274 bits (671), Expect = 6e-72
Identities = 146/342 (42%), Positives = 211/342 (61%), Gaps = 17/342 (4%)
Query: 113 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 172
+CTIGPAS N L K++ GM + R+N SHG+HE H + IR + + S
Sbjct: 6 VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDS---------- 55
Query: 173 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 232
+ I D +GP+IR G ++G ++ L+ G++ L T G++ VDY+ I N
Sbjct: 56 IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRTQP---VTGSSTEASVDYEGIAND 109
Query: 233 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 292
VK G+RI ++DG + +I + VS D + ++ GG + S KGVNLPG V LPA++EKDK
Sbjct: 110 VKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVSLPAITEKDKK 169
Query: 293 DLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-KGKNIKIISKIENHQGMVNLDEIIAE 351
D+ F +E+ VD I SF+R + + EIR + + K + +I+KIE + + N +I E
Sbjct: 170 DIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPNLIAKIETMEAIENFQDICKE 229
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+DGIM+ARGDLG+E+P + + L QK MI CNR VI ATQML+SMV PTRAE++
Sbjct: 230 ADGIMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVT 289
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAV 453
DV A+LDG + VMLS E+A G++PVE V T+ + + AE V
Sbjct: 290 DVFQAVLDGTNAVMLSAESASGEHPVESVSTLRLVSEFAEHV 331
>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
(Lyme disease spirochete)
Length = 477
Score = 273 bits (669), Expect = 1e-71
Identities = 168/476 (35%), Positives = 262/476 (55%), Gaps = 33/476 (6%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
+L+ I+ TI ++ + + G+NV R+N +H SHE + I N R+
Sbjct: 4 KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISNK----- 58
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
+A+ +DTKGPE+RT +E + +K G+ + ++TS E N T +Y
Sbjct: 59 -----IALMIDTKGPEVRTANIEN----PIIVKTGDKVIISTSP-INEPNNFQT---NYD 105
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
V G+++ IDDG + + + D L C I+N G + ++K +N PGI + L +V+
Sbjct: 106 GFVKEVPQGSKVLIDDGELEMTVVAKLPDRLICEIKNDGQIKNKKSINTPGISLKLQSVT 165
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNLD 346
EKDK + + VD I SF+R+ + +++ IL G ++KIISKIEN +G+ N++
Sbjct: 166 EKDKGFIELAAKYNVDFIAHSFVRHSKDVQDVQEILTASGNPDVKIISKIENQEGIDNIE 225
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI S GIMVARGD+G+EIP E V +AQ + C + G PVI ATQML +M++ PRPT
Sbjct: 226 EIAKASYGIMVARGDMGVEIPAEDVPIAQLKITQTCIKYGIPVITATQMLHTMIENPRPT 285
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQ--LFNDLV 464
RAE+SD+ANAIL+G D +MLSGETA G YP+E V M +I K+ E HR+ L+ D
Sbjct: 286 RAEVSDIANAILNGTDAIMLSGETAYGKYPIEAVKMMTSIAKKVEK---HRKMTLYKD-- 340
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
E+ TK + AI+V + GK+A +++ YR P+ T +
Sbjct: 341 -ELFYDKSITRNYIIKCAIDATKLMDIKAIIVDSLKGKTARIMATYRASVPLFITTNSER 399
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
AR++ L G VY +++ K V + L+ +++G V+ D ++++G
Sbjct: 400 LARELALSYG----VYSNLVDNNF-KRTTEFVVTSLKMLKEQGVVNDKDTVIIISG 450
>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
Proteobacteria|Rep: Pyruvate kinase family -
Nitrosomonas europaea
Length = 496
Score = 270 bits (662), Expect = 7e-71
Identities = 167/493 (33%), Positives = 253/493 (51%), Gaps = 20/493 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPAS N VL +M+E G++V R+NFSHG+ + H ++ R +S
Sbjct: 2 MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASVELVRSLARSLGRT 61
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+G + D +GP+IR G E G ++ LK G+ L + GN + + +DY
Sbjct: 62 VG------VLADLQGPKIRIGKFEQG---KIRLKTGDEFILDAEC---QLGNQERVGLDY 109
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ + N V+ G + +DDG I + V + C + GG+L + KG+N G + PA+
Sbjct: 110 RELPNDVEAGATLLLDDGRIVLTVAKVRESEIFCEVLQGGILSNNKGINRKGGGLSAPAL 169
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+ KD D+ D + SF R+G + R ++ E + +++KIE + ++ LD
Sbjct: 170 TAKDLLDIKTSAVIRADYLAVSFPRSGDDIRRARALMQEAQGHSLLMAKIERSEAILALD 229
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
+I+ SD IMVARGDL +E+ V QK MI K VI ATQM+ESM+ P PT
Sbjct: 230 DILEASDAIMVARGDLAVEVGDAAVPALQKRMIRSAREANKLVITATQMMESMISNPIPT 289
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE+SDVANA+LDG D VMLS E+A G YPVE V MA +C EAE + S
Sbjct: 290 RAEVSDVANAVLDGTDAVMLSAESAAGQYPVEAVEAMARVCLEAEKE--YTPSLRARRSP 347
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
I AI +T SG +A +S+ + PI A++ T
Sbjct: 348 DTQSISIEDAIARATMYAAGSLNIQAIAALTQSGVTALFMSRRSSKAPIFALSPQEDTLG 407
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SG 585
+V L+RGV PI + + + + + L +RG V D ++ G G +G
Sbjct: 408 KVTLFRGVYPIEFGQGLCDPEI--ILGMAEDEL---LKRGAVRDEDLIIMTIGEPVGKAG 462
Query: 586 FTNTVRVMLVQSA 598
TNT++++ V S+
Sbjct: 463 GTNTMKIIKVGSS 475
>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
family protein - Tetrahymena thermophila SB210
Length = 495
Score = 269 bits (660), Expect = 1e-70
Identities = 173/491 (35%), Positives = 255/491 (51%), Gaps = 54/491 (10%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+CT+GP S +V ++ K++++GMNVAR+ + HG K
Sbjct: 22 RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG--------------------LKQ 61
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G ++ D K EI+ G ++ + K+ +Y+ G+ I
Sbjct: 62 GPDIRTSLLKDKKPIEIKK-----GQKLKITFNRFLIQKVDEQPEYE--GDEQGIGCSIA 114
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ +V+ G + + D I V+ + EN G+L K V LPG+ +DLP +S
Sbjct: 115 -LSKLVQVGQHVLLSDNTIYSHVVEVNESDIVVQFENEGILNEVKNVRLPGVKIDLPTIS 173
Query: 288 EKD------KSDLLF-------------GVEQGVDMIFASFIRNGAALHEIRGILGEKGK 328
E+ K+D F G+E+GVD I SF+R+G + +R +L +G+
Sbjct: 174 EEGIFIIQFKNDQQFQLILIDEDFIISQGLEKGVDFIAVSFVRSGEDIEYVRDLLSPRGE 233
Query: 329 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
+IKII+KIEN +GM N ++I+ SDGIMVARGDLG+ IP +KVF+AQK MI RC VGKP
Sbjct: 234 HIKIIAKIENIEGMENFEDILKSSDGIMVARGDLGMVIPAQKVFVAQKWMIDRCLEVGKP 293
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
VI ATQM+ESMVK PRPTRAE SDVANA+LDG D VMLS ET+ G YP ECV + I +
Sbjct: 294 VITATQMMESMVKNPRPTRAEASDVANAVLDGTDAVMLSTETSVGQYPCECVEITSQIAR 353
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
EAE + F ++ I A IVV T G+ A L+SK
Sbjct: 354 EAEMCYNNADNFFKRTKLIR-EISDTESMATSAVQMSFDLKAPIIVVFTMYGEMARLISK 412
Query: 509 YRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFV 568
YRP +I V+ P T + + L G++ + + P+ + ++ + + ++
Sbjct: 413 YRPTAHVIVVSNEPGTIKALTLSHGIISL--KVPS----FQGIEKLIDYAINRAKELNLC 466
Query: 569 HPGDNAVVVTG 579
G+ +VV G
Sbjct: 467 KKGNKVIVVMG 477
>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma mobile
Length = 483
Score = 269 bits (659), Expect = 2e-70
Identities = 162/411 (39%), Positives = 239/411 (58%), Gaps = 10/411 (2%)
Query: 110 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 169
S +I TIGP+S+N +L++MM GM R NFSHG H AE + A K + +L
Sbjct: 17 SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGDH---AEQLNKFVLA-KEVAKELNL 72
Query: 170 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNI 229
P SL LDTKGPEIR G ++ G S ++E+ K T+ LT Y+ T + +
Sbjct: 73 PMSLM--LDTKGPEIRVGKMKDG-SQKIEVGKIITV-LTDEVSYKTFEGIPTKFTVSHRM 128
Query: 230 TNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
VK G+ I DDG ++ I V + + N +L S K +N+PG + L +S+K
Sbjct: 129 DKDVKVGSYILFDDGKLTTIVTGVKSGIVEVKTINSHVLKSNKRINIPGAQLSLEFLSKK 188
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK-GKNIKIISKIENHQGMVNLDEI 348
DK D++FG++ V+ I ASF+ + + ++R +L + G++I+IISKIE+ G+ N+DEI
Sbjct: 189 DKEDIIFGIKNDVNYIAASFVNSKQDVLDLRKLLKDNNGEHIQIISKIESVFGIENIDEI 248
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
I SDGIM+ARGDLG+EIP +V +K +I +C VGKPVI ATQML+SM K P+PTRA
Sbjct: 249 IEASDGIMIARGDLGLEIPYFEVPFYEKQIIRKCRNVGKPVIVATQMLDSMEKLPQPTRA 308
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF-NDLVSEV 467
E+SDV A GAD MLSGE+A GD+PVE V M+ I + AE +++ + L + +
Sbjct: 309 EVSDVYWATELGADATMLSGESANGDFPVESVEVMSTINRRAEKEFYNKLYYPAHLETLI 368
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAV 518
+ P+ V+++ +G+ ++++RP II V
Sbjct: 369 QNPVGVHSKLASEVALKVMNGDYKFSVILSETGRLLKEIARFRPNTVIIGV 419
>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
Proteobacteria|Rep: Pyruvate kinase II - Salmonella
typhimurium
Length = 480
Score = 269 bits (659), Expect = 2e-70
Identities = 176/499 (35%), Positives = 262/499 (52%), Gaps = 26/499 (5%)
Query: 104 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 163
S +R + I+ T+GPA+ LEK++ G NV RMNFSHGS E H RE
Sbjct: 2 SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREI---- 57
Query: 164 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 223
+AKLG +AI D +GP+IR + G +V L G+ L + E G+ + +
Sbjct: 58 AAKLGR--HVAILGDLQGPKIRVSTFKEG---KVFLNIGDKFLLDANLGKGE-GDKEKVG 111
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 283
+DYK + V PG+ + +DDG + + V + + GG L + KG+N G +
Sbjct: 112 IDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSA 171
Query: 284 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMV 343
A++EKDK+D+ GVD + SF R G L+ R + + G + KI++K+E + +
Sbjct: 172 EALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVC 231
Query: 344 N---LDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 400
+ +D+II SD +MVARGDLG+EI ++ QK +I R ++ + VI ATQM+ESM+
Sbjct: 232 DQNAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMI 291
Query: 401 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLF 460
P PTRAE+ DVANA+LDG D VMLS ETA G YP E V MA +C AE +
Sbjct: 292 TNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAMARVCLGAEKI----PSI 347
Query: 461 NDLVSEVKPPIDPXXXXXXXXXXXXTKCL--ASAIVVITTSGKSAHLLSKYRPRCPIIAV 518
N + D L +AI+ +T SG++A + S+ PI A+
Sbjct: 348 NVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISSGLPIFAM 407
Query: 519 TRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVT 578
+RH +T LYRGV P+ + +A+D + + R +G++ GD +V
Sbjct: 408 SRHERTLNLTALYRGVTPVHFD--SAADGVV----AAHEAVNLLRDKGYLVSGDLVIVTQ 461
Query: 579 GWKQGS-GFTNTVRVMLVQ 596
G + G TNT R++ V+
Sbjct: 462 GDVMSTVGSTNTTRILTVE 480
>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
Length = 527
Score = 268 bits (658), Expect = 2e-70
Identities = 155/430 (36%), Positives = 245/430 (56%), Gaps = 25/430 (5%)
Query: 102 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 160
SKSS+ L+ I+ T+GP SR+V L ++ GM+VAR +FS G +YH ET+ N + A
Sbjct: 21 SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80
Query: 161 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD 220
+S + KL A+ LDT GPE++ + + LK + LT + D ++ +++
Sbjct: 81 RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLTPNQD--QEASSE 129
Query: 221 TIYVDYKNITNVVKPGNRIFIDDGLIS--------IICQSVSADTLTCTIENGGML-GSR 271
+ +++ + VK G+ IF+ L + + V D + C N L GS
Sbjct: 130 VLPINFNGLAKAVKKGDTIFVGQYLFTGSETTSVWLEVDEVKGDDVICLSRNAATLAGSL 189
Query: 272 KGVNLPGIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRGILGEKG--K 328
++ + +DLP ++EKDK + +GV+ +D + S+ R+ + + R +L + G
Sbjct: 190 FTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREMLKKLGDLS 249
Query: 329 NIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
+I +KIEN +G+ + DEI+ E+DGI+++RG+LGI++PPEKVFL QK + +CN GKP
Sbjct: 250 QTQIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKP 309
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
+ T++++SM RPTRAE +DVANA+LDG+D ++L ET +G YPVE + T+ IC
Sbjct: 310 AV-LTRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICA 368
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
EAE V F V V P+ K AS I+ T+SG++A L++K
Sbjct: 369 EAEKVFNQDLYFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAK 428
Query: 509 YRPRCPIIAV 518
YRP P+I+V
Sbjct: 429 YRPTMPVISV 438
>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
fastidiosa
Length = 501
Score = 268 bits (657), Expect = 3e-70
Identities = 174/491 (35%), Positives = 252/491 (51%), Gaps = 23/491 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPA+ VL+ + + G+NV R+NFSHG A R A ++
Sbjct: 19 RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G I D GP+IR G G +V L L S+ G+A + V Y
Sbjct: 79 G------ILADLPGPKIRIGRFTEG---KVRLVADARFDLLADSN-APLGDATQVGVSYL 128
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ V G+ + +DDGL+ + V + T+ N G+L RKG+N G + L A++
Sbjct: 129 GLPQDVAAGDVLLLDDGLMQLQVVQVQGARIVTTVLNDGVLSDRKGLNKQGGGLSLGALT 188
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
++D+ + GVD I SF R+ +HE R I E G + ++SKIE + +VNL E
Sbjct: 189 DRDRELIGIVSRMGVDFIAVSFCRHAEEMHEARRIARECGCDAALVSKIERAEAIVNLAE 248
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+A SD +MVARGDLG+EI ++ QK +I K VI ATQML+SMV+ P PTR
Sbjct: 249 IVAASDVVMVARGDLGVEIGDAQLPGLQKKIIKEALLQNKVVITATQMLQSMVESPMPTR 308
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE+ DVANA++DG D VMLS ETA GDYPV+ V MA IC AE H+ F+
Sbjct: 309 AEVLDVANAVIDGTDAVMLSAETATGDYPVKAVEAMARICLGAE----HQFEFDTDYEMA 364
Query: 468 KPPIDPXXXXXXXXXXXXTK--CLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
+ + ++ CL +V +T SG + LS++R PI A TRH
Sbjct: 365 QRNLQRADHAIAMATMFLSEHICL-GGVVALTESGTTPRFLSRFRSHVPIYAFTRHEDVR 423
Query: 526 RQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG-WKQGS 584
R++ L RGV P+ + + ++ +R + G + PGD V +G +
Sbjct: 424 RRMVLMRGVFPMRFDSRGLTP-----REAARATIRLLVECGCMSPGDRVVFTSGEHMETL 478
Query: 585 GFTNTVRVMLV 595
G TNT+R++ V
Sbjct: 479 GATNTLRLLEV 489
>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
longum
Length = 509
Score = 268 bits (657), Expect = 3e-70
Identities = 168/480 (35%), Positives = 253/480 (52%), Gaps = 21/480 (4%)
Query: 102 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 161
++ +++R + I+ TIGP++ + L K++E GM+VAR+N SHG+ E H + N R+A +
Sbjct: 25 NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84
Query: 162 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTTSSDYQEKGNA 219
+ ++A +D +GP+IR G + G +V+L+ G+ +TT +G+
Sbjct: 85 ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITTDD---VEGDE 135
Query: 220 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGI 279
+K + PG+ I IDDG + + V + + + G + S KG+NLPG+
Sbjct: 136 HITSTTFKGLPGDCHPGDPILIDDGKVRLEVTKVEGNNVYTKVVVAGPVSSHKGINLPGV 195
Query: 280 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENH 339
V LPA++EKD++DL + + G D+I SF+R + I+ E+G+ I II+KIE
Sbjct: 196 AVSLPALTEKDEADLRWAIRTGADIIAMSFVRFATDIDRAHEIMDEEGRRIPIIAKIEKP 255
Query: 340 QGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 399
Q + NL+EI+ DG+M ARGD+ +E P E+V LA K +I + KPVI AT++L SM
Sbjct: 256 QALENLEEIVKTFDGVMAARGDMAVECPLEEVPLATKRIIELARQYAKPVIVATEVLGSM 315
Query: 400 VKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQL 459
V P PTRAE SD ANAILDG+D M S ETA G YP V TMA I A H
Sbjct: 316 VNSPVPTRAEASDCANAILDGSDATMTSNETAVGKYPDVTVATMARISGYATD---HG-- 370
Query: 460 FNDLVSEVKP-PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAV 518
D + E+K + K A AIV T +G + H +S+ RP PI +
Sbjct: 371 -FDRIPELKNLDMSSTGAVSSAAVDLADKLNAKAIVAYTQTGATVHRVSRERPAAPIYGL 429
Query: 519 TRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVT 578
T + T + L G + +E KD+ L + G V GD V+++
Sbjct: 430 TSNEHTYHWLALSWGTEAFLLKEDYHDKSRKDLMVYTDKVL---KDAGKVADGDKIVILS 486
>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
eiseniae (strain EF01-2)
Length = 496
Score = 266 bits (652), Expect = 1e-69
Identities = 177/493 (35%), Positives = 253/493 (51%), Gaps = 25/493 (5%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPAS A+LE M+ G+NV R+NFSHG + H + R A +
Sbjct: 23 RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
+ +AI D +GP+IR G G V L G L S E G+ D + +DYK
Sbjct: 78 -AGHEVAIMADLQGPKIRVGKFAEG---RVLLAPGAPFVLDASRT--EPGDIDGVGLDYK 131
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+ + VK G+ + ++DGLI + +V + + T++ GG L + KG+N G + A++
Sbjct: 132 ELPHDVKGGDLLLLNDGLIVLSVDAVRGEQVHTTVKIGGELSNNKGINKKGGGLTASALT 191
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL----GEKGKNIKIISKIENHQGMV 343
KD D+ + D + SF +N + R + E+ +I+KIE + +
Sbjct: 192 AKDMEDIRTAMGFQADYVAVSFPKNATDMEMARQLCTVAASEQRHKPGLIAKIERAEAIP 251
Query: 344 NLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKP 403
+L I+ SDGIMVARGDL +E+ V QK MI + K VI ATQM+ESM+ P
Sbjct: 252 HLQAILRVSDGIMVARGDLAVEVGNAAVPALQKKMIRMARDMDKLVITATQMMESMITNP 311
Query: 404 RPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL 463
PTRAE+SDVANA+LDG D VMLS ETA G YP+E V MA IC AEA HR L D
Sbjct: 312 VPTRAEVSDVANAVLDGTDAVMLSAETAAGRYPLETVTEMATICAAAEAAEEHR-LDADF 370
Query: 464 VSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQ 523
+ ID A AIV +T SG +A +S++ PI A+T
Sbjct: 371 TGQTFDRIDQSIAMGALFTAHHLG--AKAIVAMTDSGATALWMSRHGIHVPIYALTPKVA 428
Query: 524 TARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG 583
T R++ +YR VLP++ D D D + + + RG V GD + G G
Sbjct: 429 TQRKMAMYRNVLPLL------MDTSADRDTALAQAEQHLKSRGIVQQGDVYAITCGEPMG 482
Query: 584 S-GFTNTVRVMLV 595
+ G TN +++ +V
Sbjct: 483 APGGTNMLKICVV 495
>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
Pyruvate kinase - Magnetococcus sp. (strain MC-1)
Length = 483
Score = 266 bits (652), Expect = 1e-69
Identities = 174/500 (34%), Positives = 260/500 (52%), Gaps = 28/500 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
IR + II T+GP + + ++ + TG++ R+NFSHGSHE H R E+ +
Sbjct: 4 IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG P L I +D +GP++R G E ++EVEL +G+ L + G+ + + + +
Sbjct: 60 LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFALYKE---ERTGDINGVTLPH 111
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ V++PG + ++DG I++ V + C + GG+L RKG+N+P + + A+
Sbjct: 112 NELFQVMRPGLELLLNDGRINLRVMEVEDFGVCCEVRVGGILSDRKGLNVPAAMLPVKAL 171
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
++KD DL FG+E G+D SF++ L E R ++ + +++KIE Q + NL+
Sbjct: 172 TDKDLEDLEFGLELGIDWCALSFVQRPEDLREARKLIHGRAA---LLAKIEKPQAVDNLE 228
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI+ +DG+MVARGDLG+E PE+V QK +I C KPVI ATQMLESM+ P PT
Sbjct: 229 EIVKVADGVMVARGDLGVEYTPERVPAVQKRLIRMCREQCKPVIVATQMLESMIDAPIPT 288
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK--EAEAVIWHRQLFNDLV 464
RAE SDVANAI DGAD VMLS ETA G Y V M I + EA+ R L L
Sbjct: 289 RAEASDVANAIYDGADAVMLSAETAVGSYACNAVSVMDRIARVTEADPDCLQRNLHTPLT 348
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQT 524
+ + C AIV T +G +A +S+ R PI+ +T +
Sbjct: 349 FDNSD--NDAISKAARDVAMSRGC--QAIVAFTKTGSTALRVSRTRASVPILGLTPDIRV 404
Query: 525 ARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG- 583
AR++ + GV + SD + + V R R+ + D VV+ G G
Sbjct: 405 ARRLTMVWGVHSV-----NTSD-VSNFAEMVGKATRICRREELANTDDRIVVIAGVPFGQ 458
Query: 584 SGFTNTVRVMLVQSASMHTD 603
G TN +R+ + A D
Sbjct: 459 EGTTNILRIARIGEAERPLD 478
>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
Pyruvate kinase - Mesoplasma florum (Acholeplasma
florum)
Length = 478
Score = 265 bits (650), Expect = 2e-69
Identities = 159/415 (38%), Positives = 227/415 (54%), Gaps = 10/415 (2%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
++ + II T GP++ + ++ E GM R+NFSHG +E I ++ + +
Sbjct: 10 VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LG P S I LDTKGPEIR G G EV + TI S ++ + + V Y
Sbjct: 66 LGKPVS--ILLDTKGPEIRVGKFVDG-KQEVTANQSITIYTDAESFKNKECLSGEMTVAY 122
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+++ +K G+ I IDDG + + + V + N ++ + K VNLPG+ +P +
Sbjct: 123 -DMSVDLKIGDTILIDDGKLEMTVEEVKPGVVKAIAFNNHLVKTNKRVNLPGVDFSMPFL 181
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-KGKNIKIISKIENHQGMVNL 345
++KD +D+ +GVEQGVD I ASF+ + + EIR IL E G +I+IISKIE+ G+ N+
Sbjct: 182 AQKDINDIKYGVEQGVDYIAASFVNSAENVKEIRDILAEANGSDIQIISKIESQVGIDNI 241
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
D II SDGIM+ARGDLG+EIP V +K MI +C GK VI ATQMLE+M + P P
Sbjct: 242 DAIIEASDGIMIARGDLGLEIPYYDVPYWEKIMIRKCREAGKVVIVATQMLETMTENPAP 301
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
TRAE++DV A GAD MLSGE+A GDYP V+TMA I K AE + + + +
Sbjct: 302 TRAEVTDVYFATELGADATMLSGESAAGDYPFITVNTMATINKRAEIEFYKKAYYQTQLE 361
Query: 466 EVKPPID-PXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVT 519
K P VV++ +G +SK+RP I+ V+
Sbjct: 362 NAKNSTSGPRADIAMDLAERTRDGQYEFAVVLSRTGALLKTISKFRPNVTILGVS 416
>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
8797
Length = 489
Score = 265 bits (649), Expect = 3e-69
Identities = 158/474 (33%), Positives = 267/474 (56%), Gaps = 24/474 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II T+GPAS + +L+K++ G+++ R+NF+HG HE+ +E ++N E SA++ P
Sbjct: 17 IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHEI----SAEMEKP- 71
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ I D GP+IR G+L G E+ ++ + D N + Y+++
Sbjct: 72 -IGILGDLSGPKIRLGVLPGD---EITCRQDMRFRFIQGLD---SDNPQELTCTYESLIG 124
Query: 232 VVKPGNRIFIDDGLISIICQSVSADT--LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
++ G+ + + DG++++ SAD + C +E G++ S++GVNLPG+ + P ++EK
Sbjct: 125 DLRVGDPVLLADGMVAMRVVEKSADDEFVECVVEREGIIRSKQGVNLPGVQLSTPCLTEK 184
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK--IISKIENHQGMVNLDE 347
D SDL + VE G+D I SF+R+ + +++ + + +++KIE + + ++++
Sbjct: 185 DLSDLAWAVEHGLDYIGLSFVRSADDIRQLKEEIEKLNPEDAPHVVAKIEKIEAVSDIEQ 244
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ +D +MVARGDLG+E+ E+V + QK +I CN+ PVI ATQML+SM PTR
Sbjct: 245 ILKLTDAVMVARGDLGVEVDIERVPIIQKRIIHLCNQYRVPVITATQMLDSMQFNTFPTR 304
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVANA+LDG+D VMLSGETA G P+ V M+ I +EA ++ + S
Sbjct: 305 AEASDVANAVLDGSDAVMLSGETAVGVSPLAAVEMMSRIVREAARILSSNLHSEEATSNR 364
Query: 468 K-PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
+ + K A +V T GK+A LSK R P +A+T P TAR
Sbjct: 365 RLYAREVTEAVTMGAGITAEKLDADLMVTCTHEGKTAMALSKQRRTVPTVALTDRPATAR 424
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGL-RFGRQRGFVHPGDNAVVVTG 579
++ LY GV ++ +D ++ +++ + + +G++ GF+ G V+++G
Sbjct: 425 RMTLYWGVTSLL------TDVVEKSPSKILAFIASYGKKHGFLTTGSQIVLISG 472
>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
Pyruvate kinase - Chromobacterium violaceum
Length = 468
Score = 264 bits (648), Expect = 4e-69
Identities = 158/488 (32%), Positives = 256/488 (52%), Gaps = 24/488 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GP+S + ++ +G+N+ R+N SHGSH+ H + R AEK+
Sbjct: 2 LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+G + +D +GP++R G +K G+ + + +GNA+ + +
Sbjct: 62 IG------VLVDLQGPKLRIGKFP----QPTTVKTGDRYEFVLD---ETEGNAERATLPH 108
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
++PG+ I ++DG ++ + + + GG L S KG NLP + L A+
Sbjct: 109 PEAFEALEPGHLILVNDGKLAFEVAEMHPRRIVTRVTVGGELSSNKGFNLPHTVLPLSAI 168
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
+ KD+ D F +E+G D + SF++ A + +R I+G K + I++KIE + +L+
Sbjct: 169 TGKDRKDAEFALEEGADWVAMSFVQTAADVKALRDIVG---KRVGIVAKIEKPSAVDDLE 225
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
I +DG+MVARGDLG+E+PPE V + Q+ ++ C +G+PVI ATQMLESM+ P PT
Sbjct: 226 AIAELADGVMVARGDLGVELPPEDVPVVQRRIVHHCRHLGRPVIVATQMLESMITAPTPT 285
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE +DVA A+ +GAD VMLS ETA G YP+E V M I + E +R++ S
Sbjct: 286 RAEANDVATAVYEGADAVMLSAETAAGQYPLEAVQIMDRIIRRVENAPDYRKVMALDYSA 345
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
P D T + V TTSG S L++ RP PI+ ++ +TAR
Sbjct: 346 ADEP-DRTDAIAACVRKVSTLLPVTVAVAFTTSGASCLSLARERPSTPILGISPRLETAR 404
Query: 527 QVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGS-G 585
++ L GV + Y P A +++++ V + G V++ G G+ G
Sbjct: 405 RLTLVWGV--VAYHGPDA----ENLEDMVVKTTFCATKLSLAEQGKPMVIIAGVPFGTPG 458
Query: 586 FTNTVRVM 593
TN +R++
Sbjct: 459 STNLLRIV 466
>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
pseudomallei)
Length = 484
Score = 264 bits (648), Expect = 4e-69
Identities = 167/487 (34%), Positives = 249/487 (51%), Gaps = 24/487 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GP+S +E + G +V R+NFSHG+H HA +R+ A ++ A++
Sbjct: 13 RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G P + + LD +GP++R G G ++ KG G+A + + +
Sbjct: 69 GHP--IGVLLDLQGPKLRVGQFASG---RAQIAKGRPFVFDRDP---APGDARRVSLPHP 120
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
I + +PG+ + +DDG + +VS+ + T G++ RKGV++P + +PA+S
Sbjct: 121 EIFDAARPGHLLLVDDGKLRFRVDAVSSARIETTALLDGIVSDRKGVSVPDATLAIPALS 180
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
KD+ DL FG+ GVD + SF++ + + R ++G + I++KIE Q + N+ E
Sbjct: 181 AKDRDDLEFGLSLGVDWVALSFVQTAQDVRDARALIGARAA---IVAKIEKPQAVANIAE 237
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+ +D +MVARGDLG+E+ E V QK +I GKPVI ATQMLESM P PTR
Sbjct: 238 IVDAADAVMVARGDLGVEMSLEDVPSVQKQIIRLARAAGKPVIVATQMLESMTLAPTPTR 297
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE SDVA A+ DGAD VMLS E+A G YPVE V M I EA QL +V+
Sbjct: 298 AEASDVAAAVYDGADAVMLSAESASGQYPVEAVDFMRKIISTTEADPIQPQLMKAIVTAH 357
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQ 527
P + V T SG +A LS+ RP I+++T + AR+
Sbjct: 358 APNATDAIGAAIEVVSDTLR--LGVAVTYTASGATAIRLSRLRPSTAILSLTPRAEIARR 415
Query: 528 VHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQG-SGF 586
+ L GV V E T ++N V+ + GF VV G G G
Sbjct: 416 LTLAWGVRSRVAAEATG------IENIVEIAIEAAHAEGFATDECPIVVAAGVPFGHPGS 469
Query: 587 TNTVRVM 593
TN +R++
Sbjct: 470 TNLMRIV 476
>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 471
Score = 262 bits (643), Expect = 1e-68
Identities = 168/483 (34%), Positives = 253/483 (52%), Gaps = 20/483 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II TIGPAS + L ++++ G+++ R+NFSHG E I RE E +
Sbjct: 5 IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV--DYKNI 229
+ I D GP+IR G L G + + KG+ + L ++K D Y+ D+K I
Sbjct: 59 PITIMQDLSGPKIRIGALPG--DVALNVSKGDVLCLGP----EDKRTNDYPYIPFDHKAI 112
Query: 230 TNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 288
+ + + + + DG + + + S T + G++ SRKG+ LPG + +PA++E
Sbjct: 113 LSDLVVNDILILADGTLQFQVKEQNSNGTFLLIAQEDGIITSRKGLALPGKSIKVPAITE 172
Query: 289 KDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
KD+ DL G++ GVD + SF+++ + E + I+ G +I +I+K+E + +L+EI
Sbjct: 173 KDQKDLSDGLKLGVDAVAISFVQSAEDIIEAKRIIKANGYDIPVIAKLERRNAIEHLEEI 232
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
+ E D IMVARGDLGIE P ++ QK +I CN+ KPVI ATQML SMV P PTRA
Sbjct: 233 LKEVDIIMVARGDLGIECPLPELPAIQKRIIRACNKASKPVIVATQMLLSMVSNPTPTRA 292
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
EI+DVANA+LDGADCVMLS ETA G++PVE V M +I +AE ++ + + +E
Sbjct: 293 EITDVANAVLDGADCVMLSEETAMGNHPVETVGFMRDITTKAEELMIETRHLKEPEAEK- 351
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
K LA AIV T +G +A +S RP PI A+T + + +
Sbjct: 352 ---SAEEFLAYAACLLAEKSLAKAIVTHTMTGTAARHVSTCRPSQPIYALTPSRTSLKGL 408
Query: 529 HLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTN 588
+ GVLP + D L+ +N + F + + T +G+ F
Sbjct: 409 NFSWGVLPQYLSASSEGDLLR-TENFIMQNPTFAIGEDIIITAGQSAPHTVQPRGTNFIK 467
Query: 589 TVR 591
R
Sbjct: 468 IFR 470
>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 500
Score = 256 bits (627), Expect = 1e-66
Identities = 163/491 (33%), Positives = 263/491 (53%), Gaps = 25/491 (5%)
Query: 104 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 163
S +R + II TIGPAS N ++ +M+ +GM++AR+N SHGS +H ET++ R
Sbjct: 29 SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88
Query: 164 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY 223
+ ++G I +D GP++R L+ S ++ G+TI + ++ + I+
Sbjct: 89 NREIG------ILVDIPGPKLRV-LIH---SPPRDVVPGDTIHIAAEHEHA----SGAIH 134
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDL 283
V + V PG+ + + DG +++ LT T+ +GG + GV +PG D+
Sbjct: 135 VHPPDCIPKVCPGDVVLVGDGAVTLQVLKPGPPMLT-TVISGGTIREGMGVVIPGRRPDV 193
Query: 284 PAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGM 342
P + + G D I SF+ + + + R +L +G NI +I+KIE + +
Sbjct: 194 PYAGARFIDYIRQGAALRPDYIALSFVGSAEDIRDARTLLTREGMGNIPLIAKIECRRAV 253
Query: 343 VNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKK 402
LD+II +D +MVARGDLG+E+P E+V QK +I C++ G PVI AT+MLESMV +
Sbjct: 254 EGLDDIIRHADAVMVARGDLGVELPLEEVPYIQKLIITTCSQQGIPVITATEMLESMVSR 313
Query: 403 PRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFND 462
RPTRAE++DVANAI+DG D MLS ET+ G YP + V MA I E E + + ++ N+
Sbjct: 314 GRPTRAEVTDVANAIVDGTDATMLSAETSVGRYPGQAVVMMARIAIEIEQHLPYLRILNE 373
Query: 463 LVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHP 522
+ ++ + + AIV T SG +A +S+ RPR P++A+T P
Sbjct: 374 RSDWHEKNVEGIISYRACYIAEELE--SPAIVAFTRSGLTAERVSRCRPRSPVLALTPDP 431
Query: 523 QTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ 582
AR++ L G+ P+V+ D ++ D ++ ++ + G D V++ G
Sbjct: 432 AVARRLLLRWGIQPVVF------DPIQSADELFRAAVKIAKVTGIATSKDQLVIIAGNFS 485
Query: 583 G-SGFTNTVRV 592
G G TN ++V
Sbjct: 486 GKEGRTNMIKV 496
>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
organisms|Rep: Pyruvate kinase - Phaeodactylum
tricornutum
Length = 665
Score = 255 bits (624), Expect = 3e-66
Identities = 174/506 (34%), Positives = 255/506 (50%), Gaps = 38/506 (7%)
Query: 113 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 172
+ T+GPAS N ++EK+ G +V R+NFSHGS E E + RE E+ YS +G
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213
Query: 173 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNV 232
I D +GP++R G +EL G++ +L + KG+ + + + I
Sbjct: 214 --ILGDLQGPKLRVGEFSKPEGEFLEL--GQSFRLDLDN---AKGDNKRVQLPHPEIIKA 266
Query: 233 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 292
+ G+ + +DDG + ++ + D L C ++ GM+ RKGVN P +++ ++ KD+S
Sbjct: 267 SELGHALLVDDGKVKLVVTAKGDDYLECRVDVAGMIKDRKGVNTPDSVLEISPLTPKDRS 326
Query: 293 DLLFGVEQGVDMIFASFIRNGAALHEIRGILGEK---GK-NIKIISKIENHQGMV--NLD 346
DL + + GVD + SF++ A + EI ++ EK G+ +++KIE NL
Sbjct: 327 DLEYMLGIGVDWVALSFVQTPADMVEIHALIDEKLPSGQFKPAVMAKIEKPSCFYDDNLQ 386
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
I+ +GIMVARGDLG+E PPE V L QK +I C G+PVI ATQMLESM++ P PT
Sbjct: 387 RIVGLCNGIMVARGDLGVECPPEDVPLLQKEIIDECRNQGRPVIVATQMLESMIEVPTPT 446
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE SDVA AI DGAD +MLS E+A G +P E V I E +R +E
Sbjct: 447 RAEASDVATAIYDGADAIMLSAESAAGKFPEESVAMQQRIINRVEGDKHYRSYLKQ--NE 504
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
P P A +IV + G + SK RP PI+A+ +T+R
Sbjct: 505 PDPENTPTDAIITAARQVAKTIGAKSIVCFSLRGSTVLRASKSRPGVPILALCPFKETSR 564
Query: 527 QVHLYRGV---LP--------------IVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVH 569
Q+ L GV LP Y P D D +++ R ++G V
Sbjct: 565 QLALSWGVYSDLPKAGSYGYTVSEEDMFNYDRPMVEKSTDDFDLVLKNACRAALKKGLVS 624
Query: 570 PGDNAVVVT-GWKQGS-GFTNTVRVM 593
D+ +VVT G G+ G N +RV+
Sbjct: 625 DPDDLLVVTAGLPFGTPGAANIIRVV 650
>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
marina DSM 3645
Length = 490
Score = 250 bits (613), Expect = 6e-65
Identities = 156/470 (33%), Positives = 247/470 (52%), Gaps = 22/470 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+GPA +LE+M+ G++V R+N +HG + H+ RE S +L P
Sbjct: 15 IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIREI----SERLKRP- 69
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+A D GP+IR G L VE + I+ +++ E + +Y+ + +
Sbjct: 70 -VATLADLSGPKIRLGTLVQDPIYCVEEQMYRFIRGDVATEPNE------LVSNYEPLID 122
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
VK G+ + + DG I++ + D++TC + GG+L SR+G+NLPG + + ++ +D+
Sbjct: 123 EVKVGDNVMLADGTITMEVVEKTEDSVTCVVVAGGILRSRQGINLPGTKLGVETITPRDR 182
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ + E +D + SF+R + +++ +L +I+KIE + + NL+EI+
Sbjct: 183 DHIRWAAETDLDYVSLSFVREADDIRQLKDLLQAHESRAMVIAKIEKREALDNLEEIVEV 242
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
S+G+MVARGDLG+EI +V AQK ++ C R+G+PVI ATQML+SM K RPTRAE +
Sbjct: 243 SNGVMVARGDLGVEIDVAEVAAAQKLIVKTCTRIGRPVIVATQMLDSMTKNSRPTRAEAT 302
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DVANAILDGAD MLS ETA G++P+ + M I E ++ L N + E +
Sbjct: 303 DVANAILDGADACMLSQETAVGEHPIVVIKMMNRIMLATEKMLC-EDLSNAIRGEEIGLV 361
Query: 472 DPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
P L A +V+ T +G +A +K R I V+ R++ L
Sbjct: 362 HPVTQAVVSGATRTADLLNAKLMVMATRTGGTALTKAKIRDCIATIGVSDSKAALRRMSL 421
Query: 531 YRGVLPIVYQEPTASDWLKD-VDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
Y G++PI L+ VD ++G + G + P D V VTG
Sbjct: 422 YWGIIPIDGAPVHNGIQLRRFVD-------KWGFEAGLLKPNDRVVFVTG 464
>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
isozyme A, chloroplast precursor - Nicotiana tabacum
(Common tobacco)
Length = 593
Score = 244 bits (596), Expect = 7e-63
Identities = 159/489 (32%), Positives = 253/489 (51%), Gaps = 31/489 (6%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + +ICTIGPA+ LE++ E GMNVAR+N HG+ E+H I R +
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEEKG--- 170
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
F++AI +DT+G EI G L G SA+ E GE T S + T+ V+Y
Sbjct: 171 ---FAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVRS-FDPPLPERTVTVNYD 224
Query: 228 NITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD-- 282
VK G+ + +D G++ + + + D + C + G+L R + G V
Sbjct: 225 GFAEDVKVGDELLVDGGMVRFEVIEKIGPD-VKCLCTDPGLLLPRANLTFWRDGKLVRER 283
Query: 283 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN--IKIISKIE 337
LP +S KD D+ FG+ +GVD I SF+++ + ++ + + ++ I +I+KIE
Sbjct: 284 NAMLPTISSKDWLDIDFGIAEGVDFIAVSFVKSAEVIKHLKSYIQARARDSDISVIAKIE 343
Query: 338 NHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLE 397
+ + NL+EII SDG MVARGDLG +IP E+V Q+ ++ C ++ +PVI A+Q+LE
Sbjct: 344 SIDSLKNLEEIIQASDGAMVARGDLGAQIPLEQVPSEQQKIVQICRQLNRPVIVASQLLE 403
Query: 398 SMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHR 457
SM++ P PTRAE++DV+ A+ D +MLSGE+A G +P + + + ++ E +W
Sbjct: 404 SMIEYPIPTRAEVADVSEAVRQRGDALMLSGESAMGQFPEKALTVLRSVSLRIER-MWRE 462
Query: 458 QLFNDLV---SEVKPPIDPXXXXXXXXXXXXTKCL-ASAIVVITTSGKSAHLLSKYRPRC 513
Q ++++ S D L A+ V T +G A LLS+ RP C
Sbjct: 463 QKRHEVIELPSIASSFSDSISEEICNSAAKMANNLEVDALFVYTKNGHMASLLSRCRPDC 522
Query: 514 PIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDN 573
PI A T R+++L G++P + SD D+++ + + RG + GD
Sbjct: 523 PIFAFTTTTSVRRRLNLQWGLMPF---RLSFSD---DMESNLNKTFSLLKARGMIKSGDL 576
Query: 574 AVVVTGWKQ 582
+ V+ Q
Sbjct: 577 IIAVSDMLQ 585
>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
pneumophila|Rep: Pyruvate kinase II - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 474
Score = 243 bits (594), Expect = 1e-62
Identities = 148/432 (34%), Positives = 230/432 (53%), Gaps = 15/432 (3%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GPAS+ +L M+ G+NV R+NFSH + I R+ + +
Sbjct: 2 LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSSA-LQLIALVRKI----ADE 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
L P +A+ D +GP+IR G + + + L G+ L + G+ + + V Y
Sbjct: 57 LNHP--VAVMADLQGPKIRVGRFQ---NKSITLIDGQNFTLDCMAP-DTLGDINGVSVAY 110
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
N+ N + G+ + I+DGLI + +S + C + GG+L KG+N G + +
Sbjct: 111 PNLANELSIGDHLLINDGLIELEVIEISGSKIHCKVVEGGVLTDLKGLNRKGGGLAARTL 170
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK-IISKIENHQGMVNL 345
+EKD++DL +E VD I SF+++ + + R ++ + G I II+KIE + + +L
Sbjct: 171 TEKDRNDLRTAIEAEVDYISLSFVKDAEDIRQARALMKDYGAQITPIIAKIERMEALDHL 230
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
+II E+D IMVARGDLG+E+ +V QK +I + + K VI ATQM+ESM+ P+P
Sbjct: 231 TDIIREADAIMVARGDLGVEVGAAEVPAIQKHIIEQTRLLDKVVITATQMMESMISNPQP 290
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
TRAE+SDVANAILDG D VMLS ETA G +PV+ + + IC AE H F
Sbjct: 291 TRAEVSDVANAILDGTDAVMLSAETASGLFPVKVITMVNKICLSAEK---HASFFYHSDP 347
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
E AI+ +T SG +A +S++ PI A++ + +T
Sbjct: 348 ETCHYQRADQAIAMATMHTANHFPIQAIITLTESGDTALWVSRHHSTVPIFAISANKRTI 407
Query: 526 RQVHLYRGVLPI 537
++ L V PI
Sbjct: 408 GRLSLVNNVFPI 419
>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
Candidatus Desulfococcus oleovorans Hxd3
Length = 478
Score = 242 bits (593), Expect = 2e-62
Identities = 154/478 (32%), Positives = 251/478 (52%), Gaps = 36/478 (7%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
+I TIGP SR+ AV+EK++ G+ + R+NFSH A+ I++ RE E+
Sbjct: 5 LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
L + D GP+IR G + G A + + G+ ++L + G+A + ++ I
Sbjct: 59 ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRLGPARAKGAFGDALYLPLELAEILE 115
Query: 232 VVKPGNRIFIDDGL----ISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
+KPG + + DG+ + + + +N G++ S KG++ PG+ +DLPA++
Sbjct: 116 QLKPGAPVILSDGIPVFRVRKRLDTEAGPVFELETQNSGLVSSNKGISFPGLAIDLPALT 175
Query: 288 EKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDE 347
KD+SD+ ++ G+D + SF++ + +++ + G+ + +I KIE + + E
Sbjct: 176 AKDRSDVAAALDVGIDALALSFVQKSQDVVDLKKEMEHHGRQVPVIVKIERMNAIDHFQE 235
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
I+AE+D IMVARGDLG+E + + QK +I C KPV+ ATQML SMV P PTR
Sbjct: 236 IVAEADVIMVARGDLGLECSLPALPVIQKRIIDMCAEHQKPVVVATQMLLSMVHNPLPTR 295
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
AE++DVANAI+DGAD VMLS ETA G+YPVE +A + + H + F + ++
Sbjct: 296 AEVADVANAIMDGADAVMLSEETAVGEYPVEAAGMLAQVAE-------HTERF--MAEKM 346
Query: 468 KPPIDPXXXXXXXXXXXXTKCLAS------AIVVITTSGKSAHLLSKYRPRCPIIAVTRH 521
P P + CL + A+ T SG +A LS RP + A++ H
Sbjct: 347 GGPRRPRGKEQVGKHLAYSACLVADHAGSRALACHTVSGHTAATLSACRPARTVYALSPH 406
Query: 522 PQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
+ R + GV P V+ + +D L V++ + + G PG++ V+ +G
Sbjct: 407 LEALRYANFLWGVKP-VHVDDRIADHLDRVEHFISTS-------GAFVPGESIVITSG 456
>UniRef50_A6PUS2 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 357
Score = 239 bits (585), Expect = 2e-61
Identities = 131/299 (43%), Positives = 174/299 (58%), Gaps = 2/299 (0%)
Query: 236 GNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLL 295
G RI DDG + ++ S L C + G L + K VN+PG + +PA++ KD+ +
Sbjct: 2 GARIIFDDGAMELLVLGKSGGLLHCEAKRDGELKNHKSVNVPGAELKMPALTRKDRDFIE 61
Query: 296 FGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGI 355
+ V+ +D I SF+R+ + +R IL +I+II+KIEN QG+ NLDEI+ +DG+
Sbjct: 62 YAVKNDLDFIAHSFVRSANDVLAVRSILDTGDSDIRIIAKIENRQGVDNLDEILKAADGV 121
Query: 356 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVAN 415
MVARGDLGIEIP E+V L QK +I C GK VI ATQML+SM P PTRAEI+DVAN
Sbjct: 122 MVARGDLGIEIPLEEVPLIQKKLIRACMAAGKSVITATQMLQSMENSPLPTRAEINDVAN 181
Query: 416 AILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPIDPXX 475
A+ DG D VMLSGETA+G YPVE V M+ I +E E F + ++ +
Sbjct: 182 AVYDGTDAVMLSGETAEGVYPVEAVSVMSRILEETEKS--PDYYFTRVREQISDSDENSA 239
Query: 476 XXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGV 534
+ AIV T SG SA L + YRPR PI A + +P RQ+ L GV
Sbjct: 240 FLIHSAVEAAERLPVRAIVCNTASGLSARLCAAYRPRKPIFAFSYNPGVVRQLSLTYGV 298
>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
Pyruvate kinase - Thermoplasma acidophilum
Length = 544
Score = 239 bits (584), Expect = 2e-61
Identities = 148/435 (34%), Positives = 235/435 (54%), Gaps = 33/435 (7%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ TIGPAS + ++++M++ G+++ R+N +H + + + +S + +G
Sbjct: 5 IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
I +D KGPE+RTG GG T+K+++ DY I ++ N+ +
Sbjct: 58 ---IMIDLKGPELRTGEFAGG-----------TLKISSGKDYVM---GKDIVLNNMNVLS 100
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V+ G+RI + DG +S +S D T N G+L R VN+PG ++L ++++D+
Sbjct: 101 AVQVGDRILMSDGEVSFEVEST--DPFTIRALNDGVLRDRSRVNIPGRFIELGTITDRDR 158
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ + G+ GVD SF++ + +R + + G + IISKIE G+ N++EI+
Sbjct: 159 AFIREGIADGVDFFALSFVQKSENVDSLRDFVIDSGGDQYIISKIETKSGLDNIEEIVKS 218
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
SDGIMVARGDLG+E+P ++V LAQK +I + G I ATQ+LESMV PTRAEIS
Sbjct: 219 SDGIMVARGDLGVELPLKEVVLAQKHIIKTAHEDGDFTIVATQVLESMVNNSSPTRAEIS 278
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
D+ NAI+D AD +MLS E+A G YPV+ V T+ KE + + F+ I
Sbjct: 279 DITNAIIDNADALMLSEESAIGKYPVQAVRTL----KEVSDYVEDKVSFDSSYYFKGNTI 334
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
K + IV +T +G + ++S RP+ + A T AR++++Y
Sbjct: 335 AYSVARAAKILSDDIK--SDGIVALTHTGSTVRMISSLRPKAMVYAATVSESLARKLNIY 392
Query: 532 RGVLPIVYQEPTASD 546
GVLP+ + E A D
Sbjct: 393 FGVLPL-HMEGNAED 406
>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_95, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 573
Score = 233 bits (571), Expect = 8e-60
Identities = 154/482 (31%), Positives = 257/482 (53%), Gaps = 26/482 (5%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + ++CTIGPA + LE + +GMNVAR+N H + E+H + IR + +
Sbjct: 87 MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEEKG-- 144
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+ +++ +DT+G +I +++ G V+ + E+I L T+ + E T+ +Y
Sbjct: 145 ----YCVSVMIDTEGGQIH--VVDHGAPFSVKAEN-ESIWLFTTQKF-EGSRPFTVQANY 196
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD-- 282
+ + + G+ + ID G+ S + L C + G+L R ++ G V+
Sbjct: 197 EGFSEGITVGDEVVIDGGMASFEVIEKIGNDLRCKCTDPGLLLPRAKLSFWRDGKLVEKN 256
Query: 283 --LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENH 339
LP +S KD +D+ FG+ +GVD I SF+++ A+ +++ L K K+I +++KIE+
Sbjct: 257 YELPTISTKDWADIEFGISEGVDFIAMSFVKDANAIKQLKSYLSNKSSKSIGVLAKIESL 316
Query: 340 QGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM 399
+ + +L+EII SDGIMVARGDLG+EIP E++ + Q + C ++ +PVI A+Q+LESM
Sbjct: 317 ESLQHLEEIIEASDGIMVARGDLGVEIPLEQIPVVQAKITHVCRQLNRPVIVASQLLESM 376
Query: 400 VKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVE--CVHTMANICKEAEAVIWHR 457
V+ P PTRAE++DV+ A+ AD +MLSGE+A G Y + CV MA+ E + +R
Sbjct: 377 VEYPTPTRAEVADVSEAVRQYADALMLSGESAIGSYGQKALCVLRMASSRMELWSREENR 436
Query: 458 Q-LFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPII 516
Q + V P AI V T G+ A LLS+ RP PI
Sbjct: 437 QSALHQRQLGVSLPDRIAEQICNCAVEMADNLGVDAIFVYTKHGQMASLLSRNRPNSPIF 496
Query: 517 AVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVV 576
A T + T ++L GV P++ + +D++ + + + +G + GD +V
Sbjct: 497 AFTDNHSTRMSMNLQWGVTPLLV------ELSEDMEANITKTIDLIKMKGVLEEGDTVLV 550
Query: 577 VT 578
V+
Sbjct: 551 VS 552
>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
eutropha (strain C71)
Length = 483
Score = 231 bits (564), Expect = 6e-59
Identities = 154/489 (31%), Positives = 251/489 (51%), Gaps = 26/489 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 170
IICT+GPA+ VL +++ GM +VAR N SHG H HA I+ R+ A+
Sbjct: 19 IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73
Query: 171 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 230
F +A+ +D GP+ R G L G EL G + L +D D + V + +
Sbjct: 74 F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD-----PPDGLPVKHPALL 124
Query: 231 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 290
++ G +++ DG I + + A+ + C + G + S G+N+P + ++ D
Sbjct: 125 QALRVGESVYLADGAIRLEVKIAGAERVVCQVLVSGTVTSGSGINVPESKRSVLIPTDDD 184
Query: 291 KSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 350
+ L+F +EQ + I SF+++ L +R +L G+ +++KIE Q +V+LD I+A
Sbjct: 185 RRHLVFALEQQAEWIGVSFVQSADDLIRVRTLL-PPGQQPLLMAKIEKRQALVDLDAIMA 243
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
SDG+MVARGDLG+E ++ L QK +IA N +PVI ATQMLESMV + +PTRAE+
Sbjct: 244 TSDGVMVARGDLGVETDLAEIPLVQKRIIALANAQARPVITATQMLESMVTQEQPTRAEV 303
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDL-VSEVKP 469
+DVANA+LDG D VMLS ETA G +PV + + E R + L SE P
Sbjct: 304 TDVANAMLDGTDGVMLSAETAIGRFPVAAAEILQRVLTATETEYAVRVARDRLRASESTP 363
Query: 470 PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
+P + A AI+ +A ++++RP P++ + R++
Sbjct: 364 ATNP---ISLVACQLAARLNAKAIIAPVRDIATALGIARFRPAAPLVVMADSEDLCRRLA 420
Query: 530 LYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNT 589
+ GV P++ +++ + + + + +G PGD V+++ G +T
Sbjct: 421 VVWGVSPLL----AVAEF--EPQSCLYLASHWLCAQGLAQPGDPVVMLSTSGAAQGAADT 474
Query: 590 VRVMLVQSA 598
++VM V ++
Sbjct: 475 LQVMRVDNS 483
>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
Hrk 5)
Length = 464
Score = 230 bits (562), Expect = 1e-58
Identities = 154/487 (31%), Positives = 248/487 (50%), Gaps = 30/487 (6%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
++ T+GP+S + +++M+ G+N R+NFSH + E + R E
Sbjct: 6 LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLRP------ 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
L + D +GP IR G A +++ G+ + T SS +EK + V
Sbjct: 60 -LTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSSKTEEKY---AVPVPNGVFFE 110
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+V+ G+ + ++ G ++ + G + RK V + G + LP ++EKD
Sbjct: 111 IVREGDEVLVEGGRLAFRIVDAGPEKAVGEALLEGEVKPRKTVTVRGKDIPLPTITEKDL 170
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDEIIA 350
D+ F V+ G D I SF+R+ + + +R IL + G +++KII+KIE + +LD I+
Sbjct: 171 RDIEFSVKAGFDAIALSFVRSSSDVQRLRDILFDYGAEDVKIIAKIETKSAVEDLDSILQ 230
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
+SD +VARGDL E+++ Q+ +I+R R GKP I ATQ+LESM+ P PTR+E+
Sbjct: 231 KSDAALVARGDLANFYGLEEIYSIQRYIISRARRFGKPSIVATQLLESMISNPLPTRSEV 290
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
DV A+ GAD ++L+GETA G YPVE V+ + I +EAE R+ V +V P
Sbjct: 291 VDVITAVRMGADALLLAGETAAGKYPVESVYWLRRIVEEAE-----REPLE--VEDVAPD 343
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+ ++ I+ + G +A +SK+RP+ +I T P TAR V++
Sbjct: 344 KSDLYESIAKGVVSLAEVISGKIIAFSEKGNTARRISKFRPKAGLIVFTNDPATARYVNM 403
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTV 590
GV +VY +P+ S K N L + V+ GD V +G ++GS T+ V
Sbjct: 404 IYGV-RVVY-DPSLS---KADQNLFSKMLSKALEHNLVNLGDLVVFTSGRRRGS--TDLV 456
Query: 591 RVMLVQS 597
V V+S
Sbjct: 457 SVERVKS 463
>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
torridus
Length = 555
Score = 229 bits (561), Expect = 1e-58
Identities = 154/484 (31%), Positives = 253/484 (52%), Gaps = 30/484 (6%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
+I TIGPAS ++ +++KM G++ R+N +H + Y + + + KS +G
Sbjct: 6 LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ +D KGPE+RTG + G S +++ K I Y + N D I ++Y NI++
Sbjct: 63 ---LMVDLKGPELRTGKFKDG-SFKIDYNKKYKIS------YNKNDNPD-ILINY-NISD 110
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ I + DG + SV+ D + T + G L VN+PG + L +++++D+
Sbjct: 111 FIDDKTLIAMSDGKLRFSVDSVNGDIINVTSLDSGSLRDNSRVNVPGKLLRLGSLTDRDR 170
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ G++ V+ SF+++ ++E++ L E+ + ++ISKIE G N+DEI
Sbjct: 171 MFIEEGIKNNVNFYALSFVQSRENINELQDYLFERNCDAQLISKIETKSGYDNIDEIARA 230
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
SD IMVARGDLG+E+P ++V +AQK +I + P I ATQMLESMV PTRAE+S
Sbjct: 231 SDFIMVARGDLGVEMPLKEVTIAQKKIIDESRKYATPTIVATQMLESMVNNDSPTRAEVS 290
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAV-IWHRQLFNDLVSEVKPP 470
D+ NAI+DG D +MLS ETA G YPVE + +++I +++ I +++ + +V
Sbjct: 291 DITNAIIDGTDALMLSEETAIGRYPVEAIGYLSSISDYVDSMEIKYKEPESFAFDKVAFA 350
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
I +IV T SG +A L+S RP I +V AR ++L
Sbjct: 351 ISKGLKMISDYTN------VDSIVAFTRSGFTARLVSSMRPGKMIYSVVSSDFLARSLNL 404
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ-GSGFTNT 589
+ V+P+ E S + D+ + + + PG +VV+G G TN
Sbjct: 405 LKSVVPVKIDESMKSKEIYDILVDINRSNK-------IRPGKKVLVVSGSPYFVFGGTNE 457
Query: 590 VRVM 593
+R++
Sbjct: 458 IRLV 461
>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
Length = 498
Score = 228 bits (558), Expect = 3e-58
Identities = 138/343 (40%), Positives = 194/343 (56%), Gaps = 21/343 (6%)
Query: 116 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 175
I A +N+A L + G+NV R NFSHG +E + RE K + +
Sbjct: 36 IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGVNIST------ 86
Query: 176 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV----DYKNITN 231
LDTKGPEIR + EVE+K +++ T+ +E G ++ V N+
Sbjct: 87 MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTTK--KEIGTSEKFSVLDSTGTYNMAK 141
Query: 232 VVKPGNRIFIDDGLIS--IICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEK 289
V+PGN IF+DDG + +I +V + N +L K +NLP +P +S+K
Sbjct: 142 DVQPGNTIFVDDGKLKLEVISSNVEEGIIETIARNTWILRENKRINLPDSNYSIPFMSDK 201
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDEI 348
D++D++F ++ D I ASF+ G + EI+ IL E G ++I+IISKIE G+ +LD+I
Sbjct: 202 DRNDIIFAIKNKFDYIAASFVNTGDNVREIKKILKEHGGEHIQIISKIETMTGIKSLDDI 261
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
I ESD IMVARGDLG+E+P V +K +I C GK VI ATQML+S+ K +PTRA
Sbjct: 262 IDESDSIMVARGDLGLEVPYYDVPTYEKYIIKDCRHKGKTVIVATQMLDSLETKIQPTRA 321
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
E++DV A+ G DC MLSGETA G YP+ V MA I +E
Sbjct: 322 EVTDVFFAVERGTDCTMLSGETANGMYPINAVEVMAKIDVSSE 364
>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
Length = 548
Score = 228 bits (558), Expect = 3e-58
Identities = 151/484 (31%), Positives = 254/484 (52%), Gaps = 34/484 (7%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + ++CT+GPA V L + GM VAR+N HG +H +R R +
Sbjct: 62 LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEEEG-- 117
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
F +++ +DT+G ++ + GG+A V+ + G T S ++ + T++V++
Sbjct: 118 ----FCVSLMVDTEGSQLLVA--DHGGAASVKAEDGSEWLFT--SKRTDESHPFTMHVNF 169
Query: 227 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNL--PGIPVD- 282
+ + G+ + ID G+ + + + V D L C + G+L R ++ G V+
Sbjct: 170 DKFSEDILVGDELVIDGGMATFEVIEKVGND-LRCKCTDPGLLLPRAKLSFWRNGKLVER 228
Query: 283 ---LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIEN 338
LP +S KD +D+ FG+ +GVD I SF+++ + ++ L K ++IKI +K+E+
Sbjct: 229 NFGLPTLSAKDWADIEFGIAEGVDCIALSFVKDANDIKYLKTYLSRKSLEHIKIFAKVES 288
Query: 339 HQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLES 398
+ + NL +II SDG+MVARGDLG++IP E++ Q+ ++ C R+ KPVI A+Q+LES
Sbjct: 289 LESLKNLKDIIEASDGVMVARGDLGVQIPLEQIPAIQEAIVDLCRRLNKPVIVASQLLES 348
Query: 399 MVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQ 458
MV+ P PTRAE++DV+ A+ AD VMLS E+A G YP + + + + E+ W R+
Sbjct: 349 MVEYPTPTRAEVADVSEAVRQYADAVMLSAESAIGAYPQKALAVLRAASERMES--WSRE 406
Query: 459 -----LFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRC 513
L + P AI V T G A LLS+ RP
Sbjct: 407 ENMQKLLPQHQLAIALPDRISEQICTSAAEMANNLAVDAIFVYTKYGHMASLLSRNRPNP 466
Query: 514 PIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDN 573
PI A T + + + ++LY GV+P+ Q P ++ ++++ ++ + +G V GD
Sbjct: 467 PIFAFTDNANSRKSMNLYWGVIPL--QLPLSN----NMEDNFNQTIKLMKSKGSVKSGDT 520
Query: 574 AVVV 577
+VV
Sbjct: 521 VLVV 524
>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
Length = 485
Score = 227 bits (556), Expect = 5e-58
Identities = 142/435 (32%), Positives = 233/435 (53%), Gaps = 20/435 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II T+GPAS++ ++ K++ G+N+ R+NFSHGS + H + C + + SA+LG
Sbjct: 6 IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ + +D +GP+IR + VEL G+ L + G+ + + Y ++
Sbjct: 60 YVGVLVDLQGPKIRIACFKND---VVELVAGQRFVLDAKLA-EFDGSVSAVGLGYPDLIA 115
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIE--NGGMLGSRKGVNLPGIPVDLPAVSEK 289
+ + + +DDG I + VS + L T + N G L +RKG+NL G + PA++ K
Sbjct: 116 DLNIDDVLLLDDGRIHLQVTEVSKEELKVTTKVLNSGKLSNRKGINLLGGGLSAPALTPK 175
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVN---LD 346
D D+ D + SF RN +H R E G +++II+K+E + + + +D
Sbjct: 176 DIEDMSTAALLNADFLAISFPRNAQDIHYARKKAKEAGCDVQIIAKVERAEVVASEKAMD 235
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
E+I +D IMVARGDLG+EI ++ QK +I+R KPVI ATQM+ESM++ P PT
Sbjct: 236 EMIQAADIIMVARGDLGVEIGDARLARIQKQLISRSKYFAKPVITATQMMESMIENPMPT 295
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA--VIWHRQLFNDLV 464
RAE+ D+ANA++DG+D +MLS E+A G YPVE V M I AE V+ H+ + D+
Sbjct: 296 RAEVLDIANAVMDGSDAIMLSAESAAGRYPVEAVQAMVRIAAGAEEPNVVMHK-CWADIE 354
Query: 465 SEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQT 524
+ P + +++I+ G++ ++S+ + I AV+ +
Sbjct: 355 HLCQDPGQSFALSAMLSASQDDTPV--GMIIISEKGQTPRIMSRCQSSVYIWAVSDDIEL 412
Query: 525 ARQVHLYRGVLPIVY 539
R+ + RGV + +
Sbjct: 413 LREFSILRGVKAVYF 427
>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 474
Score = 227 bits (554), Expect = 9e-58
Identities = 145/441 (32%), Positives = 235/441 (53%), Gaps = 20/441 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+GP SR+ + + E G++V R+NFSHG H H E ++ R AE A +G P
Sbjct: 13 IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
LA D +GP++R G +GG S ++ +K I + ++ + +TI V + I
Sbjct: 68 -LATLADLQGPKVRVGKFDGG-SLKLGFRKEYRIIVGETAP-----DPETIPVPHAEIVA 120
Query: 232 VVKPGNRIFIDDG-LISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 290
+++ G+ I DDG LI + S + + G LG +KG + G + + A++EKD
Sbjct: 121 ILEEGDTILADDGKLIFTVISGGSEPRVRAEVP--GKLGDKKGFTVRGKALPVRALTEKD 178
Query: 291 KSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 350
++DL F +E GVD++ SF++ + E++ I+ + +++K+E +++L+ I+A
Sbjct: 179 RADLDFALEIGVDIVALSFVQTVEDVEEVKAIIAGRAP---LVAKLEKPAAIIHLEAIVA 235
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
+D +MVARGDLG+E PE+V + Q+ ++ +G+PVI ATQMLESM++ PTRAE
Sbjct: 236 AADAVMVARGDLGVEFAPEEVPVIQRRIVRVARALGRPVIVATQMLESMIENSAPTRAEA 295
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
SDVA AI GAD VMLS ETA G +P V M+ I + E +R+ + E +
Sbjct: 296 SDVATAIYQGADAVMLSAETAVGRHPATAVAIMSRIIRATEGADDYRRSLAEFCGEAQAE 355
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
+ A+A+ + T + + ++ R PI+ + Q RQ L
Sbjct: 356 -NAIDIVAQAALTMAEAEGAAALALRTGAFERLARFARVRGCVPILYGSLDDQRLRQACL 414
Query: 531 YRGVLPIVYQEPTASDWLKDV 551
GV P T +W +D+
Sbjct: 415 LWGVHPQRLNAGT-ENWYRDL 434
>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
Pyruvate kinase - Mycoplasma pneumoniae
Length = 508
Score = 222 bits (542), Expect = 3e-56
Identities = 133/349 (38%), Positives = 196/349 (56%), Gaps = 12/349 (3%)
Query: 124 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 183
A +E +++ G+ V R+NFSHG+HE A I+ R+ K KL P S I LDT GPE
Sbjct: 42 ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95
Query: 184 IRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK-NITNVVKPGNRIFID 242
IR + E LK E + TT+ + + N+ N VK G +I +D
Sbjct: 96 IR--VFETAPEGLKILKDSEVVINTTTKEVAKNNQFSVSDASGTYNMVNDVKVGQKILVD 153
Query: 243 DGLISIICQSVSA--DTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ 300
DG +S++ + + + + C +N + ++K +NLP +P +S KD D+ FG+
Sbjct: 154 DGKLSLVVKRIDTKNNQVICVAQNDHTIFTKKRLNLPNADYSIPFLSAKDLRDIDFGLTH 213
Query: 301 GVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDEIIAESDGIMVAR 359
+D I ASF+ + ++R L K K++K+I+KIE++ + N+D II SDGIMVAR
Sbjct: 214 QIDYIAASFVNTTENIKQLRDYLASKNAKHVKLIAKIESNHALNNIDGIIKASDGIMVAR 273
Query: 360 GDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILD 419
GDLG+EIP KV Q+ MI C K VI ATQML+S+ K +PTRAE++DV A+
Sbjct: 274 GDLGLEIPYYKVPYWQRYMIKACRFFNKRVITATQMLDSLEKNIQPTRAEVTDVYFAVDR 333
Query: 420 GADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
G D MLSGETA G +P+ V+ M I K++E ++ N ++ K
Sbjct: 334 GNDATMLSGETANGAFPLNAVYVMKMIDKQSETFFDYQYNLNYYMANSK 382
>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
pernix|Rep: Pyruvate kinase - Aeropyrum pernix
Length = 458
Score = 218 bits (532), Expect = 4e-55
Identities = 144/475 (30%), Positives = 238/475 (50%), Gaps = 35/475 (7%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+GP+S + ++L +M+ G++VAR+N SHG E + + R AE++ ++G
Sbjct: 7 IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+A+D +GP +RTG S V+L+KG+ + L + E + VD +
Sbjct: 64 ---VAVDLEGPRVRTG-----NSEPVKLEKGDLVTL----GFME----GDVPVDARQFFE 107
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+ G+ + +DDG I + +SV + + GG+LG RKGV + G DLP +S KD+
Sbjct: 108 TIDEGDIVLLDDGKIILQVESVEGFRVKARVLEGGVLGPRKGVVVRGKEPDLPPLSAKDR 167
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KNIKIISKIENHQGMVNLDEIIA 350
L F ++GV ++ SF R+ + ++R ++ G + +I +KIE G+ + EI
Sbjct: 168 RALEFFADKGVSHVYVSFARSAEHVEKVRTVVRRLGLRQARIFAKIEGPSGVSRIGEIAE 227
Query: 351 ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEI 410
SDG+++ARGDLG+ E++ Q+ ++ + K V+ AT+ L SM++KP PTR+E+
Sbjct: 228 ASDGVIIARGDLGMHYSLEELPEIQELIVWEARKRYKTVVLATEFLSSMIEKPVPTRSEV 287
Query: 411 SDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPP 470
D+ A+L AD +ML+GETA G YPV+ V MA I A +++L +P
Sbjct: 288 VDIYQAVLQTADALMLTGETAIGKYPVKSVQWMAKISSRA-----YKKLATSPPERPRPT 342
Query: 471 IDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHL 530
P + L S +VV + +G+ A L+ ++P + R V
Sbjct: 343 STP--YKLALGLVELAESLDSPLVVYSKTGRFAERLASFKPLKTFYVGVPSREVERVVRH 400
Query: 531 YRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSG 585
G PIV + L ++ R+ +H GD VV W G
Sbjct: 401 LWGAEPIVVGDYPYEAGLAKTYEKL-------RRENIIH-GDETVVEAAWSSERG 447
>UniRef50_Q57572 Cluster: Pyruvate kinase; n=6; Methanococcales|Rep:
Pyruvate kinase - Methanococcus jannaschii
Length = 447
Score = 215 bits (526), Expect = 2e-54
Identities = 150/435 (34%), Positives = 226/435 (51%), Gaps = 37/435 (8%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GP+ N L+K + ++ R N SH + +Y E N EK+ AK
Sbjct: 5 MRKTKILVTLGPSLENK--LDKAINL-IDGVRFNMSHATTDY-CEKFLNI--LEKNNIAK 58
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
+ +D KG +IR ++ LK GE K+ D + N DTI
Sbjct: 59 V---------MDLKGIKIRIKEVKLKNKI---LKMGE--KVVIGEDIKLNYNIDTI---- 100
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ G+ I I+DG I + D + +E GG + GVNLP ++LP +
Sbjct: 101 -------EEGHFILINDGKIKLRVVE-KTDKIIAVVEVGGEIKEGMGVNLPDTRIELPII 152
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
E D ++ F VE+ + I SF+RN + E++ I+ E + ++ISKIE +G+ N+
Sbjct: 153 DETDLKNIKFAVEKDFEYIALSFVRNKEDVKELKDIISEYKGDCEVISKIETKEGLKNIK 212
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
EI ESDG+MVARGDLG+E+P E + + QK ++ NR G I ATQ+L+SM+ P PT
Sbjct: 213 EIARESDGVMVARGDLGVEVPIENIPIEQKNILRIANRYGILSITATQILDSMINNPFPT 272
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAE++D+ANAI DG DC+MLS ET G YP+E + + + K A+ H + F D V
Sbjct: 273 RAEVTDIANAIYDGTDCLMLSNETTIGKYPIEAIKVLNKVAKVADE---HYEEFGDRVCL 329
Query: 467 VKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTAR 526
ID K ++ T SG++A L+SK R IIA T + +T +
Sbjct: 330 EVESID--EGLVYAVYELYKKLNTKLVITPTYSGRTAKLISKLRINSKIIAPTPNIRTLK 387
Query: 527 QVHLYRGVLPIVYQE 541
++ L GV + +E
Sbjct: 388 RLRLVWGVESCLMEE 402
>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
Pyruvate kinase - Nosema bombycis
Length = 441
Score = 214 bits (523), Expect = 5e-54
Identities = 144/444 (32%), Positives = 237/444 (53%), Gaps = 37/444 (8%)
Query: 109 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 168
++ II T+ S + L ++ G+++ R+N SHG+ H +I N R+ K ++G
Sbjct: 5 MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60
Query: 169 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKN 228
I LDT+GPE+R + E +E+ LK+G+ I T S+ + ++ I++ +
Sbjct: 61 --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGDKI---TFSNVR---TSNKIFLPIPD 109
Query: 229 ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSE 288
T ++I++DD +++I S T N L + K +LPG+ +
Sbjct: 110 FTKFPLK-SKIYLDDAMLAIEVLETSKCECTGRAMNSHRLKNNKKASLPGLVFEDNESEA 168
Query: 289 KDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
+DK D ++ +D++FASFI + + ++ ++G + ++ I SKIE +G+ N+DEI
Sbjct: 169 RDKKDFEIILKHKIDVVFASFINSRKEVESLKKLIGSE--DVLIFSKIETLRGVENIDEI 226
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
I SDGIM+ARGDLG+E+ K+F QK + +C KPVICATQMLE+M++ P P+RA
Sbjct: 227 IEVSDGIMIARGDLGVEMTASKMFSTQKKITIKCREAKKPVICATQMLETMIQNPVPSRA 286
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
EI+DV NA+ D D ++LSGETA G +P V TM I ++AEA +H ++ + + +
Sbjct: 287 EITDVGNAVFDQFDGLLLSGETAVGKFPTLTVRTMRKIIEDAEA--YHFEISD---HKNR 341
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
P+ T+ S V+ + L P+ V++ Q R +
Sbjct: 342 CPL------------LGTRIKESCAVIRCPDLATIFGLYSNHFEIPVYFVSKEVQNFRCL 389
Query: 529 HLYRGVLPIVYQEPTASDWLKDVD 552
H+ RGV+P Y+ D +K VD
Sbjct: 390 HMLRGVIP--YEIKEDEDIIKVVD 411
>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
Pyruvate kinase - Sulfolobus solfataricus
Length = 452
Score = 214 bits (523), Expect = 5e-54
Identities = 152/451 (33%), Positives = 242/451 (53%), Gaps = 41/451 (9%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+ T+GP+S K + ++V R+NF+HG H R + ++Y+
Sbjct: 1 MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTYA-- 51
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
P S +I +D GP++R G L+ +E+KKG+ I + +K D I VD
Sbjct: 52 ---PES-SIIVDLPGPKLRLGELK----EPIEVKKGDKIV------FSQK---DGIPVDD 94
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAV 286
+ + VK + I I DG I + +S + D + T+ GG+L SRKG+N+P + + +
Sbjct: 95 ELFYSAVKENSDILIADGTIRVRVKSKAKDRVEGTVIEGGILLSRKGINIPNVNLK-SGI 153
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
++ D L ++ G D I SF+ + + +++ +G++ +I+KIE + + NL
Sbjct: 154 TDNDLKLLKRALDLGADYIGLSFVISENDVKKVKEFVGDEAW---VIAKIEKSEALKNLT 210
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
I+ ESDGIMVARGDLG+E E + L Q+ ++ GKPVI ATQ+L SM+ P PT
Sbjct: 211 NIVNESDGIMVARGDLGVETGLENLPLIQRRIVRTSRVFGKPVILATQVLTSMINSPIPT 270
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSE 466
RAEI D++N+I+ G D +MLS ETA G+YPVE V T+ NI E + HR +
Sbjct: 271 RAEIIDISNSIMQGVDSIMLSDETAIGNYPVESVRTLHNIISNVEKSVKHRPI------- 323
Query: 467 VKPPIDPXXXXXXXXXXXXTK-CLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
P++ +K A IVV + SG S +S+ RP II V+ P+ A
Sbjct: 324 --GPLNSESDAIALAAVNASKVSKADVIVVYSRSGNSILRVSRLRPERNIIGVSPDPRLA 381
Query: 526 RQVHLYRGVLPI-VYQEPTASDWLKDVDNRV 555
++ L GV+PI + ++ + D + DV ++
Sbjct: 382 KKFKLCYGVIPISINKKMQSIDEIIDVSAKL 412
>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
aurantiaca DW4/3-1
Length = 515
Score = 211 bits (516), Expect = 4e-53
Identities = 110/263 (41%), Positives = 165/263 (62%), Gaps = 12/263 (4%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
+R + I+CT+GPAS++ +LE ++E GM+VAR+NFSHGSHE HAE I R A S K
Sbjct: 10 MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
L ++ I D +GP+IRTG G + LK+G +TT D KGN D + Y
Sbjct: 66 LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT--DESVKGNDDIVSTTY 118
Query: 227 KNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
++ V PG+RI +DDGL+ + + ++ L + GG L + KG+NLPG+ V A
Sbjct: 119 AHLAADVNPGDRILLDDGLLELKVLETDKKQLLRTQVVIGGTLKNNKGINLPGVAVRADA 178
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
++ KD+ DL+FG+++GVD + SF+R A + R + E G+ + I++K+E + + L
Sbjct: 179 LTPKDREDLVFGIKEGVDFLALSFVRQPADIELARQAMAEAGRQVPIVAKLEKPEAIARL 238
Query: 346 DEIIAESDGIMVARGDLGIEIPP 368
D I+ ++DG+MVARGDLG+EIPP
Sbjct: 239 DAILDKTDGVMVARGDLGVEIPP 261
>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 466
Score = 206 bits (504), Expect = 1e-51
Identities = 136/423 (32%), Positives = 217/423 (51%), Gaps = 20/423 (4%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II +IGP+S + V+ ++ E G++ R+NF+HG E REAE+ K G P
Sbjct: 8 IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
LA+ D GP IR G ++ ++L G+ + + E G+ I + + +
Sbjct: 63 -LALIGDLVGPSIRLGRVKN----PIKLNAGDRAEFRCVEE-SEGGDTKIIPLPVRRVYE 116
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V+ G+ I +DDG + + VS + + SRK + + G LP +S++D
Sbjct: 117 VLDEGDLIVMDDGRVRLRVLEVSGYSAIVEALTPATITSRKAIAIRGKDPGLPTLSQRDV 176
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ F ++ G D I S +R + +R I+ +G + I KIEN + NL +II
Sbjct: 177 EHVKFALDNGFDYIALSHVRTRDDVDALRLIVLREGGDAGIAVKIENKSAVENLQDIIRA 236
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+D ++VARGDLG+ E+V + Q+ ++A VGKPVI ATQ+LESM++ P PTRAE++
Sbjct: 237 ADLVVVARGDLGMTYGLEEVPVLQERIVAAARSVGKPVIVATQLLESMIENPVPTRAEVT 296
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DV A+ G D +ML+GETA G YP+E + + I AE V+ H + + P
Sbjct: 297 DVYVAVRQGVDGLMLTGETAIGRYPIEAIRWLRKIITRAEQVL-HIERYT--------PK 347
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
D K A+ I+V + +G ++ RP P++ T PQ AR++ +
Sbjct: 348 DKRWAYAASIVETAEKLSAALILVYSITGSLPPWIAASRPMVPVVIGTGSPQRARRLAVL 407
Query: 532 RGV 534
G+
Sbjct: 408 WGL 410
>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
marinus F1|Rep: Pyruvate kinase - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 469
Score = 204 bits (499), Expect = 4e-51
Identities = 128/430 (29%), Positives = 224/430 (52%), Gaps = 17/430 (3%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II TIGP+S VL ++++ G++ R+NFSHG+ E ++ RE + Y ++
Sbjct: 6 IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYEREI---- 61
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+I D GP++R G L E+K +T+KL E+ +TI V + +
Sbjct: 62 --SIMGDLPGPQVRIGELP-----VQEIKAKQTVKLVYKDKVDEE---NTIPVPNRKVFE 111
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+++ G+ + IDDG I + + + + N +L K + + G +DLP +SEKD
Sbjct: 112 ILELGDIVLIDDGKIILRIIDIGGNEAEAIVLNDAVLYPHKTLVVFGKEIDLPVLSEKDV 171
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ + V + + + SF+R + + +R I+ I +I+KIE + NL +I++
Sbjct: 172 DLVNYSVSRKLTYLAISFVRRSSDIVIVRDIVSRLNGEIGLIAKIETRSAVKNLKDIMSV 231
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
SD I++ARGDLG+ E++ Q+ + +GKP I ATQ+LESMV PRP+R+E+
Sbjct: 232 SDAIIIARGDLGMHYSLEELPGLQRKIAREAIMIGKPSIVATQLLESMVNYPRPSRSEVV 291
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
DV NA+ D D ++L+ ETA G YPVE V + I AE+ I R++ D+ +++ +
Sbjct: 292 DVVNAVYDLVDALLLTDETAIGKYPVESVKWLKRIISSAESSIVERRI-EDIREKLE--L 348
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
+ + + I++ T + +S++RP+ P+ T A ++ +Y
Sbjct: 349 RALREKYALGLTLLAEKINAKILIYTKTSTIPPAISRFRPQIPVYVGTSDKLIAEKLTIY 408
Query: 532 RGVLPIVYQE 541
G+ P ++
Sbjct: 409 YGLKPFYLKQ 418
>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
Length = 553
Score = 203 bits (495), Expect = 1e-50
Identities = 141/491 (28%), Positives = 242/491 (49%), Gaps = 26/491 (5%)
Query: 100 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 159
+D + I CT+GP+S NV V+ M+ G ++ R+NFSHG+ + H + ++A
Sbjct: 30 VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89
Query: 160 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 219
+ + K ++AI D +GP++R + +ELK+G+ L ++ G+
Sbjct: 90 MQ-LTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTLDHNN---VNGDE 139
Query: 220 DTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLP 277
+Y+ +K V +P + I ++DG I ++ SV A + ++ GG LG+RKG+ +P
Sbjct: 140 SRVYLPHKEFFAVCEPNDDIILNDGYIRLVATSVDRQAMRIVTRVKTGGKLGARKGITIP 199
Query: 278 GIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-KGKNI-----K 331
+ L +S KD D+ G+D I SF++ A + E R + + +N +
Sbjct: 200 TRILPLSGLSPKDLGDIRNACRLGMDWIALSFVQTKADVIEARDYIAKLHAENPASFCPR 259
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
+ SKIE ++++D+I SD +MVARGDL IE KV QK + R G +
Sbjct: 260 VCSKIEKPTAVLDIDDIALLSDMLMVARGDLAIETCLSKVCSIQKYICERARYHGCQAMV 319
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANI---CK 448
ATQM+ES+++ PTRAE++DVA+ DGA+ V+++ ETA G PV V + +I +
Sbjct: 320 ATQMVESLIENTVPTRAEVTDVASVCFDGANSVLVTAETAAGHDPVNVVKVLRSILTTTE 379
Query: 449 EAEAVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSK 508
++EA I N + + A I+V + SG S + +
Sbjct: 380 QSEAFIKQVLTDNYINQRTSKEHKRPDSIALGACLLARELGAKLIIVFSKSGNSTGRVLR 439
Query: 509 YRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFV 568
P CP++ +T ++ + +H+ G P+++ P D +K + + + G
Sbjct: 440 QLPHCPVLCITSEQRSYQWLHMCWGCRPVLH--PGNIDSMKTL---ISVADTHALESGQA 494
Query: 569 HPGDNAVVVTG 579
GD V+V G
Sbjct: 495 ERGDAVVLVFG 505
>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
parvum|Rep: Pyruvate kinase - Ureaplasma parvum
(Ureaplasma urealyticum biotype 1)
Length = 474
Score = 174 bits (424), Expect = 5e-42
Identities = 111/331 (33%), Positives = 173/331 (52%), Gaps = 16/331 (4%)
Query: 126 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 185
++ ++ +G+N+ RMN SHG + H + ++ K+ I DTKGPEIR
Sbjct: 41 IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIKV------EILFDTKGPEIR 94
Query: 186 TGLLEGGGSAEVELKKGETI---KLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFID 242
+ +K E I K + E D N+ + VK +RI ID
Sbjct: 95 VCEMSDNNFI---IKNSEVIIHCKEKVLGSFNEFSVTDA--TGQYNMISDVKINHRILID 149
Query: 243 DGLISIICQSVS--ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQ 300
DG + +I + + + + T +N L + K +NLP LP +S+KD D+ V+
Sbjct: 150 DGKLILIVKKIDFLKNIIYTTAKNSYSLKTNKRLNLPDANYSLPFLSKKDIDDINLAVKL 209
Query: 301 GVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARG 360
+ + SFI N ++E++ +L + K+I+KIE + + NL+EII +DGIMVARG
Sbjct: 210 KIPYLALSFISNIKQINEVKQLLKKSSFIPKLIAKIETQEAIDNLEEIIKNTDGIMVARG 269
Query: 361 DLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDG 420
DLG+E+P K+ + Q ++ C++ K I ATQML+S+ + PTRAE++DV A+
Sbjct: 270 DLGLEVPFYKIPIYQNKIVELCHKYNKYCIIATQMLDSLERNIIPTRAEVTDVYYAVKQK 329
Query: 421 ADCVMLSGETAKGDYPVECVHTMANICKEAE 451
+ MLSGETA G P+ V M +I E E
Sbjct: 330 VNATMLSGETAAGIDPINAVQVMKSIILETE 360
>UniRef50_A3H760 Cluster: Pyruvate kinase; n=1; Caldivirga
maquilingensis IC-167|Rep: Pyruvate kinase - Caldivirga
maquilingensis IC-167
Length = 456
Score = 167 bits (405), Expect = 1e-39
Identities = 126/449 (28%), Positives = 209/449 (46%), Gaps = 29/449 (6%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ TIGP+S V K+++ ++ AR+NFSHG I R S
Sbjct: 7 IMATIGPSSEKPEVAGKLIKL-IDGARVNFSHGDLNTWVSRIELIRRINPS--------- 56
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ I D GP +RTG + ++ KG+++ +++ KG + V K +
Sbjct: 57 -IPILGDLPGPGVRTGEM-----VDLPFSKGDSLTFKLANE--GKGY---VPVPVKEFFD 105
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+V G+ I +DDG I + ++ +T G++ + K + + LP + ++DK
Sbjct: 106 IVDKGDVIIMDDGRIRLEVTGKGSNEVTVVALTNGIIRTHKSITIMNKDYPLPILGDRDK 165
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ + ++ + S +R+ + R L + II K+E + ++ +I
Sbjct: 166 EAIKVAAKYNLEYLGLSHVRSVEDIESTREYLRSLNYSPMIIVKVETASAIRSIKDIACN 225
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+D +MVARGDLG+ E+V Q+ +I + GKPV+ ATQ+LESMV P PTRAE+
Sbjct: 226 ADYVMVARGDLGMVFNLEEVPKIQEKIITAAHSCGKPVMVATQLLESMVNNPVPTRAEVV 285
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPI 471
D+ ++L G D ++L+ ET G+YPVE V + I E + + V + +
Sbjct: 286 DIMTSVLQGVDSLLLTDETTMGNYPVEAVEWLRRIVSNYEDQVTPGFRADSSVFDER--- 342
Query: 472 DPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLY 531
+ + IVV T SG +A LS+YRPR I+A T R++ L
Sbjct: 343 ----MRFALGVAELADSIGAKIVVFTKSGLTAVRLSRYRPRVQILAGTPSEAVFRRLKLL 398
Query: 532 RGVLPIVYQEPTASDWLKDVDNR-VQSGL 559
GV V + + D N ++ GL
Sbjct: 399 WGVESRVINDQDYDKGMVDTLNEYIKEGL 427
>UniRef50_Q22CT0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 747
Score = 165 bits (400), Expect = 4e-39
Identities = 103/316 (32%), Positives = 171/316 (54%), Gaps = 12/316 (3%)
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
++ KD +D+ + +D I S +R+ + +R ++GE + ++I++KI+ + + N
Sbjct: 439 ITPKDITDINHCINNDIDCICVSNVRSARDIKAVRNLIGED-RGVRIMAKIQTPESVENF 497
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
+EI+ SDG+ +ARG L + +P EK+F QK MI +C+ KPV+ + +L+SMV P
Sbjct: 498 EEIVKASDGVQIARGYLTVHMPVEKLFAKQKEMIHKCHEHLKPVLVSCNILDSMVSSLLP 557
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFN---- 461
T E+ +++N + D D ++LS ET+ G++PV+ + T++ IC EAEA+ ++L N
Sbjct: 558 TMCEVGEISNLVNDYVDNIVLSSETSCGNHPVQAIKTLSRICVEAEALRIMKRLQNPSHS 617
Query: 462 DLVSEVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRH 521
D+VS + AS I+V TT G +A LSK RP CPIIAVT H
Sbjct: 618 DIVSIKSQSNAIPCCIINCSLEAAYQVHASVIMVFTTRGYTALKLSKLRPPCPIIAVTCH 677
Query: 522 PQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWK 581
+ AR + V I++ ++ L RV L+ G + GD V+ +G
Sbjct: 678 KKVARNLSSVSAVNSILFGSLIGTEVL---IKRVIDKLKL---TGLLKVGDFVVITSGDI 731
Query: 582 QG-SGFTNTVRVMLVQ 596
+ + TN +R+ VQ
Sbjct: 732 ENLANQTNNLRIYTVQ 747
Score = 46.8 bits (106), Expect = 0.002
Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 13/147 (8%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA-EKSYSAK 166
R + I+ TI + L+ M+E G+N +N ++ + + T+R R+A EK + +
Sbjct: 66 RRTKIVGTISSFYSSYENLKSMVEAGLNSFMVNMAYCTPDLLV-TLRKHRDALEKEFDIQ 124
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
L P + + KG +R G L E+ L+KG+ ++ + ++ GN+ VD
Sbjct: 125 L--PITCVL----KGTLVRIGTLM---QPEIFLRKGQEYRIVLN--HKVLGNSLYCAVDD 173
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSV 253
K I VK GN+I ID G IS+ + +
Sbjct: 174 KEIIRRVKVGNQILIDYGQISMTIKRI 200
>UniRef50_A3EXR5 Cluster: Pyruvate kinase-like protein; n=2;
Coelomata|Rep: Pyruvate kinase-like protein -
Maconellicoccus hirsutus (hibiscus mealybug)
Length = 133
Score = 164 bits (398), Expect = 7e-39
Identities = 75/132 (56%), Positives = 91/132 (68%)
Query: 470 PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
P D KC A+AI+VITTSG+SAHL+SKYRP CPIIAVTR+ Q ARQ H
Sbjct: 2 PTDATHAVAIAAVEAAHKCNAAAIIVITTSGRSAHLISKYRPSCPIIAVTRYEQVARQSH 61
Query: 530 LYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNT 589
L+R +LP+ Y+ P +DWLKDVD RVQ G++FG RGF+ D VVVTGW+QGSGFTNT
Sbjct: 62 LHRAILPLYYEAPQQADWLKDVDCRVQYGIQFGTCRGFIKTKDPIVVVTGWRQGSGFTNT 121
Query: 590 VRVMLVQSASMH 601
+RV+ H
Sbjct: 122 MRVVAADQILTH 133
>UniRef50_Q22AI0 Cluster: Pyruvate kinase, barrel domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyruvate kinase, barrel domain containing protein -
Tetrahymena thermophila SB210
Length = 837
Score = 163 bits (395), Expect = 2e-38
Identities = 100/320 (31%), Positives = 169/320 (52%), Gaps = 23/320 (7%)
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
+S KD +D+ + +D + S +R + ++ + K KII+KI+ +G+ N
Sbjct: 532 ISAKDITDITNALNHDIDSVCVSNVRTAEDIRVVKRHC--QSKQTKIIAKIQTLEGVQNY 589
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
DEI+ SD +++ARG L + IP EK+ QK +I + N KPV+ + +L+SMV P
Sbjct: 590 DEILKVSDAVLIARGYLTVHIPVEKLHFKQKELIQKSNESLKPVLVSCNILDSMVSSLLP 649
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
T E+ +++N + D D ++LSGET+ G YP++ V T++ IC E EA RQ+ +L +
Sbjct: 650 TTCEVGEISNLVSDYVDAIILSGETSYGMYPIQAVETLSRICMETEA----RQILKNL-N 704
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCL--------ASAIVVITTSGKSAHLLSKYRPRCPIIA 517
+ PI KC A+ I+V T++G +A +SK RP CPIIA
Sbjct: 705 DTTRPIQ-IQWSKQSVINSIVKCTLDAAYNIQANLIIVFTSTGSTALKVSKLRPPCPIIA 763
Query: 518 VTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVV 577
VT + + AR ++ V V+ ++ L + L + + + +V GD ++
Sbjct: 764 VTSNHKVARHINYLSSVTGKVFFTLVGTNVL------TEKVLEYAKDQKYVKSGDYVIIT 817
Query: 578 TGWKQG-SGFTNTVRVMLVQ 596
+G + SG TN ++++ VQ
Sbjct: 818 SGEIENLSGMTNNLKIVQVQ 837
>UniRef50_Q8ZYE0 Cluster: Pyruvate kinase; n=4; Pyrobaculum|Rep:
Pyruvate kinase - Pyrobaculum aerophilum
Length = 461
Score = 150 bits (363), Expect = 1e-34
Identities = 112/429 (26%), Positives = 203/429 (47%), Gaps = 31/429 (7%)
Query: 113 ICTIGPASRNVAVLE--KMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 170
+ T+GP++ + E K ++ ++ R+N +H S ++ EA +SY P
Sbjct: 20 VATLGPSTDVLRPDELIKFLDL-VDGVRINLAHAS----PNEVKFRIEAVRSYEKAKNRP 74
Query: 171 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 230
LA+ +D KGP IR G ++ + +++GE +K S +K + I V K
Sbjct: 75 --LAVIVDLKGPSIRVG-----STSPINVQEGEVVKFKLS----DKSDGTYIPVPNKAFF 123
Query: 231 NVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 290
+ V+ + I + DG + + + +D + E+ G++ K + + G D+ +E+D
Sbjct: 124 SAVEQNDVILMLDGRLRLKVTNTGSDWIEAVAESSGVITGGKAIVVEGKDYDISTPAEED 183
Query: 291 KSDL--LFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEI 348
L + + +D + S ++ + +R +L E G ++ KIE + NL+E+
Sbjct: 184 VEALKAISPIRDNIDYVAISLAKSCKDVDSVRSLLTELGFQSQVAVKIETKGAVNNLEEL 243
Query: 349 IAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRA 408
+ SD ++VARGDLG+ + + + Q+ ++ + GKP+ ATQ+L+SM P PTRA
Sbjct: 244 VQCSDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSMQSSPIPTRA 303
Query: 409 EISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
EI+DV G D + L+ ETA G YP+ V ++ I E I
Sbjct: 304 EINDVFTTASMGVDSLWLTNETASGKYPLAAVSWLSRILMNVEYQI-----------PQS 352
Query: 469 PPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQV 528
P + + L + I+V + SG A ++K+RPR + T + + AR +
Sbjct: 353 PLLQNSRDRFAKGLVELAQDLGANILVFSMSGTLARRIAKFRPRGVVYVGTPNVRVARSL 412
Query: 529 HLYRGVLPI 537
+ + P+
Sbjct: 413 SIVWALEPL 421
>UniRef50_Q648E3 Cluster: Pyruvate kinase; n=1; uncultured archaeon
GZfos3D4|Rep: Pyruvate kinase - uncultured archaeon
GZfos3D4
Length = 588
Score = 146 bits (354), Expect = 2e-33
Identities = 73/132 (55%), Positives = 89/132 (67%)
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
+I+KIE Q N+DEII +DGIMVARGDLG+++ P++V QK +I CN GKPVI
Sbjct: 256 VIAKIETKQAWRNIDEIIDVADGIMVARGDLGLQVDPQEVPSIQKKIIKLCNLRGKPVIT 315
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
AT+ML SM P PTRAE +DV NAILDG D VMLSGET+ G YP V M NI ++AE
Sbjct: 316 ATEMLSSMENNPEPTRAESTDVFNAILDGTDAVMLSGETSSGKYPAHAVRMMVNIAEQAE 375
Query: 452 AVIWHRQLFNDL 463
+ L DL
Sbjct: 376 EYFEQKGLSTDL 387
Score = 47.2 bits (107), Expect = 0.001
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 491 SAIVVITTSGKSAHLLSKYRPRC-PIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLK 549
+AIV T +G++A ++S++RP II V TA+++ L GV P+ + +
Sbjct: 479 AAIVASTLTGRTARMISRFRPSIKAIIGVVHDIHTAKKLVLSSGVYPLNIGKEKNGEKYS 538
Query: 550 DVDNRVQSGLRFGRQRGFVHPGDNAVVVTG 579
++D + L+ + G V GD + + G
Sbjct: 539 NMDEMFEEALKLATEEGRVQRGDKVIFIGG 568
Score = 42.3 bits (95), Expect = 0.037
Identities = 53/213 (24%), Positives = 90/213 (42%), Gaps = 36/213 (16%)
Query: 134 MNVARMNFS-HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 192
++V RMN + H E + RE +K G ++A+ D GP+IR G G
Sbjct: 2 VDVIRMNMAFHKGGETERAIFKWLRENKK------GMTKNVAVLGDLPGPKIRLG---GV 52
Query: 193 GSAEVELKKGETIKL---TTSSDYQEKGNADTIYVDYKNITNVVKPGNR----------- 238
G A +++ KGE L + + K ++ V+ K VVK N
Sbjct: 53 GGA-IKVSKGEHFDLYFRKRNEVSKSKRAGASVLVNDKPFEEVVKKINEYDGIGDYIGES 111
Query: 239 --------IFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKD 290
I I DG + + S + C +E G + KGV + +D P+ ++D
Sbjct: 112 IRNNKDVVISIADGSVILKAVGESEGVVECEVEKEGEIKDHKGVTIKRAELDAPSFEQRD 171
Query: 291 KSDLLFGVEQGVD---MIFASFIRNGAALHEIR 320
K L F +++G D + SF+++ + ++R
Sbjct: 172 KEALRFLLDEGGDFLGFVGVSFVKDAEDVLKVR 204
>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_171, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 622
Score = 144 bits (349), Expect = 6e-33
Identities = 115/355 (32%), Positives = 185/355 (52%), Gaps = 34/355 (9%)
Query: 108 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
R + I+ T+G + N ++ ++++G + R+N +HG+ +E IR R + S
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE----KGNADTI 222
L P I +D GP++RTG ++ G V L+ G+ + ++ S ++ + D
Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMKAG-PCFVRLRVGDLLIISLDSSIEQDELTQPTVDAY 370
Query: 223 YVDYKN--ITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 276
V + + + VKPG I DDG I + Q SA + +I + G LG+ K +N+
Sbjct: 371 RVTCPSSFLFDSVKPGEPIAFDDGKIWGVIQGTSASEIIVSITHASPRGTKLGAEKSINI 430
Query: 277 PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK--NIKIIS 334
P + ++ KD DL F V DM+ SFIR+ + +R L EK K N+ I+
Sbjct: 431 PESNIRFEGLTTKDLMDLEF-VAAHADMVGISFIRDVRDIVVLRAEL-EKRKLHNLGIVL 488
Query: 335 KIENHQGMVNLDEIIAESD------GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKP 388
KIE G L ++ E+ G+M+ARGDL +E E++ Q+ +++ C+ P
Sbjct: 489 KIETSSGFDKLPLLLLEAMKSPNPLGVMIARGDLAVECGWERLGDIQEEILSICSAAHVP 548
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 443
VI ATQ+LES+VK PTRAE++DVAN A C+ML+ KG + V+ V T+
Sbjct: 549 VIWATQVLESLVKSGVPTRAELTDVANG--RRASCIMLN----KGKHIVDAVSTL 597
>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
Length = 501
Score = 141 bits (341), Expect = 6e-32
Identities = 110/359 (30%), Positives = 177/359 (49%), Gaps = 32/359 (8%)
Query: 108 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
R + I+ T+ A + +L ++ GMN AR+N H S + N R AE+
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT---IY 223
+ I +D GP++RTG L + + L+KGE + L ++ D+ +
Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAEEGRSACEDSPARVV 251
Query: 224 VDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGI 279
I V+ G + DDG I + + V+ D + I + G L + KG+N P
Sbjct: 252 CAVSGIYGGVQVGEAVLFDDGKIESVVRGVAQDEIQLEITRADDKGSRLAADKGINFPES 311
Query: 280 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIEN 338
+ L +SE+D L F V + D++ SF + ++ LGE+G ++ I+ KIE
Sbjct: 312 RLKLRGLSEQDLEHLDF-VARRADIVGMSFANEPEDVFALQAALGERGAGHLGILLKIET 370
Query: 339 HQGMVNLDEIIAES-----DGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICAT 393
+G L +I + G+M+ARGDL +E E+ Q+ ++ C PV+ AT
Sbjct: 371 RRGFEQLPRLILAAMRSYPAGVMIARGDLAVECGWERTAEVQEEILWLCEAGHMPVVWAT 430
Query: 394 QMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANI-CKEAE 451
Q+LE + KK P+RAEI+D A+ A+CVML+ KG + VE VH++A+I C+ E
Sbjct: 431 QVLEKLAKKGLPSRAEITDA--AMSQRAECVMLN----KGPHIVEAVHSLADILCRMQE 483
>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
tenax|Rep: Pyruvate kinase - Thermoproteus tenax
Length = 446
Score = 139 bits (336), Expect = 2e-31
Identities = 109/425 (25%), Positives = 194/425 (45%), Gaps = 30/425 (7%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+ T+GP++ + + ++ V R+N SH S + R+ E++ S
Sbjct: 5 IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+AI D +GP +RTGL+ +++ G + + EKG+ + V +
Sbjct: 58 YIAIIADLRGPSVRTGLMR-----PLQITAGARVSFKLA----EKGDG-FVPVPRREFFE 107
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
V++ G+ + + DG + + S + + + G++ S K + + G + E+D
Sbjct: 108 VIEEGDEVLMLDGKLVLRIISAAQTSAEAESLSSGVISSNKAIVVKGKEYHIEQPVEEDI 167
Query: 292 SDL--LFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 349
L L VD + S +R+GA + ++R ++ E G I++KIE + ++EII
Sbjct: 168 RALQTLSRFRDDVDYVALSLVRDGADVRKMRSVVEEAGLTSGIMAKIETKSAVDKIEEII 227
Query: 350 AESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAE 409
+D I++ARGDL + E + Q+ ++ R G+PV ATQ+L+SM PTRAE
Sbjct: 228 NAADYIVIARGDLALHYGLEYIPKVQRLLVERSLSAGRPVAVATQLLDSMQTNTTPTRAE 287
Query: 410 ISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKP 469
++DV G D + L+ ETA G++P+E V + I + E F L +
Sbjct: 288 VNDVYTTASLGVDSLWLTNETASGEHPLEAVDWLRRIVSQVE--------FGRL--KAAS 337
Query: 470 PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
P D + + I V + +G A ++K+RP + + AR +
Sbjct: 338 PAD-ARDRFAKAVVDMAEDMGGEIAVYSMTGTLAKRIAKFRPMTTVYVGVNERRLARMLE 396
Query: 530 LYRGV 534
L V
Sbjct: 397 LREDV 401
>UniRef50_A0BDA7 Cluster: Pyruvate kinase; n=3; Alveolata|Rep:
Pyruvate kinase - Paramecium tetraurelia
Length = 700
Score = 138 bits (334), Expect = 4e-31
Identities = 79/253 (31%), Positives = 131/253 (51%), Gaps = 4/253 (1%)
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
++ KD +D D I S + +HE++ +LG NI+I +I +G+ N
Sbjct: 292 ITSKDINDFTIAKRLDFDSITLSNVSRPEEVHELKHLLGSS-TNIQIFVRITTQEGINNF 350
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
D+I+ +DG ++AR L E V Q MI C ++ KPV+ +TQ+LESM+ + P
Sbjct: 351 DKIMEIADGCIIARAYLATWAQIEDVVQMQHDMILNCRKLVKPVLISTQILESMLTQTNP 410
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVS 465
T AE+ D+A+ + D +MLSGET G++P++ V +A I E H +L +
Sbjct: 411 TFAEMGDIADVVEQHIDGIMLSGETTYGNHPIKVVQALARISTNIE---MHTRLQYQGLF 467
Query: 466 EVKPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTA 525
++K +P L ++++ T+G++A LSK CPI+AVT A
Sbjct: 468 QIKIQENPIASIIAQNAIENAYSLRVKLILLFTTGETALSLSKLHAPCPIVAVTAKKTIA 527
Query: 526 RQVHLYRGVLPIV 538
R +++ GV+P +
Sbjct: 528 RNLNIVNGVIPFL 540
Score = 49.2 bits (112), Expect = 3e-04
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMN--FSHGSHEYH-AETIRNCREAEKSYS 164
R + I+C+I + + ++ +M++ G N +N ++H +Y + IR+ E E +
Sbjct: 29 RRTKIVCSINEKTCEIDIIREMLKAGANALSINTAYTHDRRQYEKLKMIRDQLEQELDH- 87
Query: 165 AKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV 224
++ I + +G R G L E+ LKKG I++T D + G+ + I V
Sbjct: 88 -------TIPINMMLQGKITRIGHLR---QPEIYLKKGNIIRIT--QDNKVIGDENIICV 135
Query: 225 DYKNITNVVKPGNRIFIDDGLISIICQSVSAD 256
D + K G++IFID G I + +++ D
Sbjct: 136 DQDELFTQAKVGDQIFIDYGQIVLNIKALETD 167
>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
Pyruvate kinase - Thermococcus litoralis
Length = 220
Score = 134 bits (324), Expect = 7e-30
Identities = 74/219 (33%), Positives = 128/219 (58%), Gaps = 12/219 (5%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II TIGPAS+ ++KM++ GM+VAR+NFSHG+ E HA+TI R+ + ++
Sbjct: 14 IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERRV---- 69
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
AI D G ++R G ++G V L+KG+ + LTT +G+ TI V++K++
Sbjct: 70 --AILGDLPGLKMRVGKIKGDS---VTLRKGDKVVLTTRDI---EGDETTIPVEFKDLPK 121
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+V G+ I++ DG I + + V + + C + NGG+L S KG+N+P + + A++ +D
Sbjct: 122 LVSKGDTIYLSDGYIMLRVEEVRENEVECVVVNGGILFSHKGINIPKANLPIEAITPRDF 181
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNI 330
+ F +E GVD I SF+ + + +++ L +K ++
Sbjct: 182 EIIEFAIEHGVDAIGLSFVGSVYDVLKVKSFLEKKSADL 220
>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_11, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 475
Score = 130 bits (314), Expect = 1e-28
Identities = 85/230 (36%), Positives = 118/230 (51%), Gaps = 18/230 (7%)
Query: 356 MVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVAN 415
MVARGDLG E+P E+V L Q+ +I RC+ + KPVI AT MLESM+ P PTRAE+SD+A
Sbjct: 243 MVARGDLGAELPIEEVPLLQEDIIRRCHSMQKPVIVATNMLESMINHPTPTRAEVSDIAI 302
Query: 416 AILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVKPPID--P 473
A+ +GAD VMLSGETA G YP++ V M + E + L + PP P
Sbjct: 303 AVREGADAVMLSGETAHGKYPLKAVKVMHTVALRTE---------SSLSTSTTPPSQTIP 353
Query: 474 XXXXXXXXXXXXTKCLASAIVVI-TTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYR 532
L ++++ + +G A LS YRP I A T + +++ LY
Sbjct: 354 YKAIIWVQCLLSMPPLWLTLLILPSLTGSMAITLSHYRPSSTIFAFTNEERVKQRLVLYH 413
Query: 533 GVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQ 582
GV+PI Q SD D + L +G + G++ +V Q
Sbjct: 414 GVMPIFMQ---FSD---DAEETFSRALSILVNKGLMKEGEHVTLVQSGAQ 457
Score = 101 bits (242), Expect = 6e-20
Identities = 59/178 (33%), Positives = 98/178 (55%), Gaps = 13/178 (7%)
Query: 142 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 201
SHG H H +TI +E + K+ +AI LDTKGPE+R+G + + LK+
Sbjct: 2 SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVP----KPIMLKE 52
Query: 202 GETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCT 261
G+ T + +T+ V+Y + N V+ G+ + +D G++S++ +S S D + C
Sbjct: 53 GQEFNFTIKRGVSSE---NTVSVNYDDFVNDVEVGDILLVDGGMMSLVVKSKSKDLVKCQ 109
Query: 262 IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASF-IRNGAALHE 318
+ +GG L SR+ +N+ G LP++++KD D+ FGV+ VD SF +N +HE
Sbjct: 110 VIDGGELKSRRHLNVRGKSATLPSITDKDWEDIKFGVDNQVDFYAVSFWEKNYHMMHE 167
>UniRef50_Q5M6U9 Cluster: Pyruvate kinase; n=2; Campylobacter
jejuni|Rep: Pyruvate kinase - Campylobacter jejuni
Length = 319
Score = 129 bits (312), Expect = 2e-28
Identities = 100/329 (30%), Positives = 161/329 (48%), Gaps = 30/329 (9%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
+I T GP+ L ++ + + R+N +HG E TI N R+ +
Sbjct: 4 LILTTGPSLGGKINLNQIHQDKF-IYRINGAHGDIESIKNTIINLRKQKAD--------- 53
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+ I +D G +IRT G S ++++K + L +YK
Sbjct: 54 -IDILIDLPGNKIRTS----GISEAIQVEKDKDFSLKIDQ------------FNYKEFYK 96
Query: 232 VVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDK 291
+VKPG ++ +D + I + V+ + T ++ G+L + KG+++ + ++P + EKDK
Sbjct: 97 LVKPGMEVYANDSVFLFIVKEVNDKEIIFTSKSTGLLLNNKGMHVRNLHDNIPFLFEKDK 156
Query: 292 SDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAE 351
+ E + + ASF+R + + EI+ +L N KIISKIE + + NL I+ E
Sbjct: 157 ELIKLCNEFDIAYVGASFVRKASDIQEIKQVLHS---NTKIISKIETLEAVNNLYSILQE 213
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+ I++ RGDL EI EK+ Q ++ + V ATQ+L++M +KP PT AEI
Sbjct: 214 VEYILIDRGDLSTEIGIEKIPRFQNYIVEMAHHNAIKVFLATQILKNMEEKPIPTIAEID 273
Query: 412 DVANAILDGADCVMLSGETAKGDYPVECV 440
D+ N G V LS ETA G Y ECV
Sbjct: 274 DLYNIAKSGVFGVQLSEETAVGHYVEECV 302
>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
Length = 745
Score = 128 bits (309), Expect = 4e-28
Identities = 67/123 (54%), Positives = 82/123 (66%), Gaps = 1/123 (0%)
Query: 330 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN-RVGKP 388
I IISKIE + N++ II SDGIM+ARGDLGIE + + QK +I C + KP
Sbjct: 442 IAIISKIEKPSAIKNIENIIKLSDGIMIARGDLGIETNLSNLPILQKKLINLCRIKYNKP 501
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
VI ATQM+ESM P PTRAE++DVA A+ DG+DCVMLS ETA G YP+ V T I K
Sbjct: 502 VIVATQMMESMRFLPSPTRAEVTDVATALYDGSDCVMLSAETATGQYPILTVSTQNKIIK 561
Query: 449 EAE 451
+ E
Sbjct: 562 DVE 564
Score = 100 bits (239), Expect = 1e-19
Identities = 70/226 (30%), Positives = 109/226 (48%), Gaps = 22/226 (9%)
Query: 113 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 172
I TIGPAS N LEK+ G++V R+NFSHG I + R EK Y +G
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157
Query: 173 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
I D +GP+IR G + E + VELK+G+ + GN + + ++Y
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGDLFSFDLMNSL---GNQNRVQLNY 212
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADT-------LTCTIENGGMLGSRKGVNLPGI 279
+ K G I +DDG + + + DT + + GG L S+KG +P +
Sbjct: 213 PELIKNAKAGQIILLDDGNLKMKILENNYDTSNIQNSYIKVQVLTGGKLYSKKGFCIPNM 272
Query: 280 PVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 325
+ + +SEKD D+LF + + VD + SF++ L +R I+ +
Sbjct: 273 IMPIDVLSEKDIKDILFCINEEVDFLGYSFVQTEYDLIFLRNIIND 318
>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
Clostridium beijerinckii NCIMB 8052
Length = 340
Score = 125 bits (302), Expect = 3e-27
Identities = 100/345 (28%), Positives = 166/345 (48%), Gaps = 24/345 (6%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II T+GP ++ AVL+ ++E+G+N R NF HGS E E ++ ++ +
Sbjct: 3 IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKS---------- 52
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQE--KGNADTIYVDYKNI 229
+ + LD G ++R + G ++ GE I Y E K + + I V NI
Sbjct: 53 DIQVMLDLSGTKVR---VSGKFQYIFKVYNGEVIYFCGEDKYSEVVKNSKNKIKVIPLNI 109
Query: 230 TNVV---KPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPA 285
N + K +I I D ++ I V TI GG++ KG N+ +
Sbjct: 110 KNKILNEKDYKQIGIKDNTMTFDIVDKVDGLIKAITI-RGGVIRKWKGCNIKNLERKELP 168
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKN---IKIISKIENHQGM 342
++E DK +++GV VD+I SF+ + +++ L + N KI +KIE G+
Sbjct: 169 LNENDKDAIVWGVNNKVDIICQSFVEEKKDIDDVKLFLNNRKSNQFKPKIWAKIETLNGV 228
Query: 343 VNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIAR-CNRVGKPVICATQMLESMVK 401
N+ I++E+DGI++ RGDL E E + ++ +I K +I AT +L SM
Sbjct: 229 NNIKSILSEADGIVIGRGDLIPETSIEDTPIYEERIIKEVLGDKDKEIIIATHILNSMKN 288
Query: 402 KPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANI 446
P+ +E+ + N I GA +L+GET+ G P+ V + N+
Sbjct: 289 GKMPSISEVESIYNFIKIGATGFLLAGETSIGKAPIRTVEFLNNL 333
>UniRef50_A0NLM6 Cluster: Pyruvate kinase; n=2;
Alphaproteobacteria|Rep: Pyruvate kinase - Stappia
aggregata IAM 12614
Length = 512
Score = 120 bits (289), Expect = 1e-25
Identities = 99/329 (30%), Positives = 160/329 (48%), Gaps = 23/329 (6%)
Query: 119 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 178
A+ + A + ++ GMNVAR+N +H E + + R A A+L + I +D
Sbjct: 165 AADDPAFVRDLVRKGMNVARLNCAHDGPEAWEKMAAHVRTA-----AELEGR-DVRILMD 218
Query: 179 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGN-ADTIYVDYKNITNVVKPGN 237
GP+IRT + +L GE +L + A T V + N ++ G+
Sbjct: 219 IAGPKIRTETVVPQKKTP-KLTIGERFRLVVQETPDAHSDIAVTASVSLPQMVNRLREGD 277
Query: 238 RIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 293
R+ DD + + + VS + ++G + +KG+NLP + + ++ KDK+D
Sbjct: 278 RLLYDDSKLEGVVEEVSNGEAVIRVTRAKDSGVKIKPQKGINLPDTALGVSPLTAKDKTD 337
Query: 294 LLFGVEQGVDMIFASFIRNGA---ALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIA 350
L V DM+ SF+ L E +G + I++KIE + + NL +IA
Sbjct: 338 LKT-VTALADMVGYSFVSEPDDIDLLEEALASIGAANHPLGIVAKIERPEAVQNLPALIA 396
Query: 351 ESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
+ G IM+ARGDL EI E++ Q+ ++ C PVI ATQ+LES+VK P
Sbjct: 397 RASGTRPLAIMIARGDLASEIGFERLAEMQEEILWICEAASTPVIWATQVLESLVKFGSP 456
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGD 434
+R +++D A A A+CVML+ A G+
Sbjct: 457 SRGDMTDAAMAA--RAECVMLNKGPAVGE 483
>UniRef50_Q8XLL6 Cluster: Pyruvate kinase; n=3; Clostridium
perfringens|Rep: Pyruvate kinase - Clostridium
perfringens
Length = 364
Score = 119 bits (286), Expect = 3e-25
Identities = 97/338 (28%), Positives = 161/338 (47%), Gaps = 22/338 (6%)
Query: 126 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 185
++ +++ G N+ RMN SHG H R+ E + ++ I LD +G +IR
Sbjct: 30 IDNIVKGGGNIIRMNLSHGKH----------RDVECCIDYIRSNHKNVKILLDLQGNKIR 79
Query: 186 TGLLEGGGSAEVELKKGETIKLTTSSDYQEK-GNADTIYVDYKNITNVVKPGN---RIFI 241
G ++ G+ + + Y N D + NI N N +I++
Sbjct: 80 VANNIYG---TFKVNSGDLVYFCSEETYDAYLKNIDRNKLIPLNIKNKFIYNNTFKKIYM 136
Query: 242 DDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 301
D + I S + + ++ GG++ KG NLP + VSEKD D+ F ++
Sbjct: 137 KDATMEFIVISNNNGLIKTKVKLGGVVRKEKGCNLPNLDRKNWGVSEKDLEDIKFAIDNK 196
Query: 302 VDMIFASFIRNGAALHEIRGILGEKGKNIKII----SKIENHQGMVNLDEIIAESDGIMV 357
VD+I S+ E + I+ + K+ + I KIE ++G+ N+ E+ E DGI++
Sbjct: 197 VDIIDYSYCSYMEECREFKNIVFKNLKSNQFIPKLWGKIETNEGINNIKEVAKELDGIVI 256
Query: 358 ARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESM-VKKPRPTRAEISDVANA 416
ARGDL EI V + Q+ ++ K +I AT +L S+ K+ +PT E+SD+ +
Sbjct: 257 ARGDLTAEIGILNVPIVQEKILYALKNENKSIIVATNVLSSIRNKQNKPTINELSDIYHF 316
Query: 417 ILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVI 454
I GA ML+GET+ G+ V T+ N K E ++
Sbjct: 317 IRCGATGFMLTGETSTGENEEYVVTTLKNSIKYYEKLL 354
>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 710
Score = 117 bits (281), Expect = 1e-24
Identities = 94/265 (35%), Positives = 132/265 (49%), Gaps = 22/265 (8%)
Query: 197 VELKKGETIKLTTSSDYQEKG----NADTIYVDYKNITNVVKPGNRIFIDDGLISIICQS 252
V LK G+ + +T E A + + + VKPG I DDG I + +
Sbjct: 437 VRLKVGDLLVITREGSLDEPSVTVPGAHRLTCPSGYLFDSVKPGETIGFDDGKIWGVIKG 496
Query: 253 VSADTLTCTIEN----GGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 308
S + +I + G LGS K +N+P + ++ KD DL + V DM+ S
Sbjct: 497 TSPSEVIVSITHARPKGTKLGSEKSINIPQSDIHFKGLTSKDIKDLDY-VASHADMVGIS 555
Query: 309 FIRNGAALHEIRGILGE-KGKNIKIISKIENHQGMVNLDEIIAESD------GIMVARGD 361
FIR+ + +R L + K ++ I+ KIE G NL I+ E+ GIM+ARGD
Sbjct: 556 FIRDVHDITVLRQELKKRKLDDLGIVLKIETKSGFKNLSLILLEAMKCSNPLGIMIARGD 615
Query: 362 LGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGA 421
L +E E++ Q+ +IA C PVI ATQ+LES+VK PTRAEI+D ANA A
Sbjct: 616 LAVECGWERLANMQEEIIAICKAARVPVIMATQVLESLVKSGVPTRAEITDAANA--KRA 673
Query: 422 DCVMLSGETAKGDYPVECVHTMANI 446
CVML+ KG VE V + I
Sbjct: 674 SCVMLN----KGKNIVEAVSMLDTI 694
Score = 37.1 bits (82), Expect = 1.4
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 108 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
R + I+ TIG A+ + + +++ G +V R+N +HG E I+ R S
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGG 192
L P + +D GP++RTG L+ G
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313
>UniRef50_A0BIN1 Cluster: Pyruvate kinase; n=2; Paramecium
tetraurelia|Rep: Pyruvate kinase - Paramecium
tetraurelia
Length = 509
Score = 116 bits (279), Expect = 2e-24
Identities = 109/456 (23%), Positives = 209/456 (45%), Gaps = 45/456 (9%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI-RNCREAEKSYSAKLGSP 170
IIC++ N +L M+E G N +N ++ ++ + + +N + E + K+ P
Sbjct: 9 IICSVSENCSNYELLRSMVEAGCNAFTINMAYIKNKGSLQILDKNRCQLEAEFKTKI--P 66
Query: 171 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNIT 230
+L + +G IR G L+ E +++G + LT SD + GN I +D
Sbjct: 67 INLIL----RGQVIRVGQLQ---DPETLIEEGNIVYLT--SDQHKVGNNQLIPIDSNEFL 117
Query: 231 NVVKPGNRIFIDDG-----LISI-----ICQSVSADTL---------TCTIENGGMLGSR 271
+ +++ ID G L+ I + + + D + C G L S
Sbjct: 118 EKLNINDKLAIDYGHIILELLDIQMFDQVYEKIGIDKMCLLSGVKIYVCRCCKTGTLKSF 177
Query: 272 KGVNL--------PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 323
K +++ + ++E+D D+ + E D I S + + +++ L
Sbjct: 178 KPISIFIENKAQKEEEQQEQVPMTEQDILDIDYACECNFDSITFSKVNTALDIIKVKERL 237
Query: 324 GEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCN 383
+K ++++ ++I L+EII +DG ++AR + + P E V Q +I+ C
Sbjct: 238 EQKYPHVQVFARIAEKLKEEQLEEIITLADGCIIARSHISMTQPVEDVVKYQTQIISSCR 297
Query: 384 RVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 443
++ KPV +T +LESM + +P+ A++ D++N + D ++LSGE + G +PV V T+
Sbjct: 298 KLFKPVFVSTYILESMSVQLKPSFADMGDISNIVKQYIDGILLSGEASFGKFPVLIVQTL 357
Query: 444 ANICKEAEAVIWHRQLFNDLVSEVKPPID----PXXXXXXXXXXXXTKCL-ASAIVVITT 498
NIC++ E + ++LF+ + ++ P L A AI+++T
Sbjct: 358 NNICRKIEKKLL-QELFDQPQQRDQYQVNFTGQPIATVIAKSCVEMAYILNAKAILMLTR 416
Query: 499 SGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGV 534
++ LSK R C II+++ + Q R ++ V
Sbjct: 417 RIQTTLKLSKLRASCKIISISDNQQICRCLNYINNV 452
>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
Pyruvate kinase - Theileria parva
Length = 699
Score = 116 bits (278), Expect = 2e-24
Identities = 61/123 (49%), Positives = 77/123 (62%), Gaps = 1/123 (0%)
Query: 325 EKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
E + II KIE + ++ EI+ SDG+MVARGDLGIE + + QK +I C
Sbjct: 407 ENLSGVGIIPKIEKQAALDDIHEILKVSDGLMVARGDLGIETDLANLPIVQKRLIQLCRV 466
Query: 385 V-GKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTM 443
V KP I ATQMLE+M P PTRAE+SDV+NA+ DGAD VMLS E+A G YP V+
Sbjct: 467 VYRKPCIVATQMLETMRSSPTPTRAEVSDVSNAVFDGADAVMLSAESATGHYPKASVNVQ 526
Query: 444 ANI 446
+
Sbjct: 527 RRV 529
Score = 93.5 bits (222), Expect = 2e-17
Identities = 69/238 (28%), Positives = 121/238 (50%), Gaps = 22/238 (9%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIRNCR--EAEK 161
+ L+ + T+GPA+ N ++ + + G++V R+NFSH S H ++TIR E K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175
Query: 162 SYSAKLGSPFS-LAIALDTKGPEIRTG----------LLEGGGSAE-VELKKGETIKLTT 209
+Y +I D +GP++R G +L G E VELK G+ L T
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIGKFMPNLDVPGVLPGSKGCEFVELKAGD---LFT 232
Query: 210 SSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENGGM 267
Y G+ + +D+ I +K G++I +DDG +S+ + + ++T ++N
Sbjct: 233 FDAYDVLGSKSRVQLDFPEILKELKVGDKILLDDGNLSMTVVKTNPEEPSVTAEVKNDYK 292
Query: 268 LGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE 325
L SRKG ++P + + + + EKD D +F + GVD + SF++N + + + IL +
Sbjct: 293 LSSRKGFSVPKVVLPIEFLDEKDVKDAIFCLGIGVDFLGVSFVQNKSDILYLINILND 350
>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
Babesia bovis|Rep: Pyruvate kinase family protein -
Babesia bovis
Length = 693
Score = 115 bits (276), Expect = 4e-24
Identities = 61/123 (49%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Query: 330 IKIISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRV-GKP 388
I II KIE + +++ I+ SDG+M+ARGDLG+E + + QK +I C V KP
Sbjct: 403 IAIIPKIEKQPALDDINGILEVSDGMMIARGDLGVETEITNLPVIQKRLIQLCRLVYHKP 462
Query: 389 VICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICK 448
VI ATQMLESM P+P+RAE +D ANA+ DGAD VMLS E+A G YP V T +
Sbjct: 463 VIVATQMLESMKSNPKPSRAEATDCANAVYDGADAVMLSAESATGAYPAHSVRTQRLLLY 522
Query: 449 EAE 451
AE
Sbjct: 523 NAE 525
Score = 99 bits (238), Expect = 2e-19
Identities = 66/238 (27%), Positives = 117/238 (49%), Gaps = 20/238 (8%)
Query: 103 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 162
+ ++ L+ + T+GP++ L +ME G ++ R+NFSHG+ + R R+ E
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164
Query: 163 YSAKLGSPFSLA----IALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 207
S+ GS + I D +GP++R G +E + VELKKG+
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224
Query: 208 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSAD--TLTCTIENG 265
T + KG+ + ++ +I + GN I +DDG +++ SV D ++T + N
Sbjct: 225 DT---HDVKGSQTRVRFNFPDILRDLNVGNTIAMDDGNLNLEVISVDRDAPSVTAVVLND 281
Query: 266 GMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGIL 323
G+L SRKG +P + + + SEKD D +F G+D + SF++ + ++ I+
Sbjct: 282 GVLSSRKGFAVPNVAITVDLFSEKDVKDTIFSYALGLDFLGVSFVQRMTDILYLKNII 339
>UniRef50_Q062W1 Cluster: Pyruvate kinase; n=1; Synechococcus sp.
BL107|Rep: Pyruvate kinase - Synechococcus sp. BL107
Length = 359
Score = 113 bits (273), Expect = 1e-23
Identities = 99/366 (27%), Positives = 177/366 (48%), Gaps = 28/366 (7%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
+I T+GP+S + ++L + + G + R+N SH + E + SY L +
Sbjct: 6 LIVTVGPSSISKSILIGLDKAGADCFRINLSHSNEEEYY-----------SYFQALSNA- 53
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNAD----TIYVDYK 227
+ +DT+G + R ++E G+ LK+GE++ S + D + +++K
Sbjct: 54 GIRPCIDTQGAQGR--IIEVYGNKN--LKEGESVDFLFGSHQRNMRKVDDSNEVLVLNHK 109
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTC--TIENGGMLGSRKGVNLPGIPVDLPA 285
I V + + ID + I +++ + + + GG + ++ P+ L
Sbjct: 110 EIIEQVSIDDILRIDFSGLIIKIKTIDRENKSFKGVVIAGGTCEKNRAFDIANKPLILKP 169
Query: 286 VSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNL 345
+E D + + IF SF + + R + KG++ K+I+KIE+ +G+ ++
Sbjct: 170 HTEFDIWAIKESTKHSCPAIFHSFAESAEDIKTTRSLC--KGQS-KVIAKIESRRGLESI 226
Query: 346 DEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
EI SDGI++ RGDL EI V +A C + KP+ AT +L+S++ P
Sbjct: 227 KEIATASDGILIDRGDLSREISISMVPVAVNLATKLCVEIEKPIYVATNVLDSLMSNSLP 286
Query: 406 TRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA-VIWHRQLF--ND 462
+RAEISD+ N + G ++L+ E A G P+E V + +I K EA + +F ND
Sbjct: 287 SRAEISDIHNMLTMGVTGMVLAAEVAIGARPIESVQVVNHIRKIVEAQKLGILGIFNSND 346
Query: 463 LVSEVK 468
L +E+K
Sbjct: 347 LKTELK 352
>UniRef50_Q3J5D7 Cluster: Pyruvate kinase; n=2; Rhodobacter
sphaeroides|Rep: Pyruvate kinase - Rhodobacter
sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
DSM158)
Length = 508
Score = 113 bits (272), Expect = 1e-23
Identities = 90/322 (27%), Positives = 163/322 (50%), Gaps = 25/322 (7%)
Query: 119 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 178
A+ + A++ +++ G + R+N +H E A I + R++E+ KL I++D
Sbjct: 161 AASDPAIVRELVAAGADAFRINCAHDGPEAWAAMIGHIRKSERMTGRKL------PISMD 214
Query: 179 TKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNR 238
GP+ R + + GG L+ G+ +G + + + + + PG +
Sbjct: 215 LGGPKFR--VTKTGGPLPKRLQAGDRFAFVEKPSLAPEGRGWAM-LGHPALLAALAPGVQ 271
Query: 239 IFIDDG-LISIICQSVSADTLTCTI---ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDL 294
+ +DDG L + + Q+ L E G L +GVNLPG +D+ A++E+D + L
Sbjct: 272 VSVDDGKLWATVIQTGRGHALLEVDRVGERGLKLKPGRGVNLPGSHLDVAALTEEDLAAL 331
Query: 295 LFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIK----IISKIENHQGMVNLDEIIA 350
V + D++ SF++ + + + + + + I+ KIE G+ L E+I
Sbjct: 332 DVVVAEA-DLVAFSFVQTPGDVRALIAAMEARACHPRPLPAILLKIETPMGLHLLPELIV 390
Query: 351 ESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRP 405
E+ G +M+ARGDL +EI +++ Q+ ++ C PV+ ATQ+LE MVK+ +
Sbjct: 391 EAGGSLPVGVMIARGDLAVEIGFDRLSEIQEEILWLCEAAKVPVVWATQVLEGMVKEGQA 450
Query: 406 TRAEISDVANAILDGADCVMLS 427
+RAE++D A+ ADCVML+
Sbjct: 451 SRAEVTDA--AMSQRADCVMLN 470
>UniRef50_Q5D8L3 Cluster: SJCHGC03591 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03591 protein - Schistosoma
japonicum (Blood fluke)
Length = 146
Score = 113 bits (272), Expect = 1e-23
Identities = 52/126 (41%), Positives = 74/126 (58%)
Query: 470 PIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVH 529
P +P T ASAI V+TTSG+SA ++ + P CP++A+ R P+ AR+ H
Sbjct: 3 PWNPGYFACLAAVEASTTSNASAIFVVTTSGRSALDIASFHPACPVVAIMRRPEIARKCH 62
Query: 530 LYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNT 589
RG+ P VY S+W D+D R+ + F ++RGF+ GD +VVTG + GSG TNT
Sbjct: 63 STRGIHPFVYTGEKLSEWSDDMDERLNAAFNFAKKRGFIGDGDQIIVVTGQEAGSGSTNT 122
Query: 590 VRVMLV 595
VR+ V
Sbjct: 123 VRIFEV 128
>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
Pyruvate kinase - Synechococcus sp. (strain
JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
B-Prime)
Length = 476
Score = 113 bits (271), Expect = 2e-23
Identities = 94/345 (27%), Positives = 167/345 (48%), Gaps = 26/345 (7%)
Query: 108 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
R + I+ T+ A+ +L +++E GMNVAR+N +H + + + R+AE +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
I LD GP+IRTG + + ++ +G+ I LT + +
Sbjct: 178 C------KILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLTAKVPEASADISCQVTCSL 230
Query: 227 KNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNLPGIPVD 282
+ ++ G ++IDDG I + + ++ G L + KG+N P +
Sbjct: 231 PEVLAHLQVGATVWIDDGKIGARVVRIEPAGVVLEVDKVAPQGKKLRAEKGLNFPDSQLQ 290
Query: 283 LPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK--NIKIISKIENHQ 340
+ ++++KD DL F V D++ SF++ A L + L + ++ +I K+E +
Sbjct: 291 IRSLTDKDCQDLDFVVRHA-DLVGYSFVQQPADLQLLVSELERRQARPDLGLILKMETQR 349
Query: 341 GMVNLDEIIAESDG-----IMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQM 395
+ NL +IA G +M+ARGDL +EI ++ Q+ ++ C PV+ ATQ+
Sbjct: 350 AVKNLPALIATVAGCRPLGVMIARGDLAVEIGWLRLGEIQEELLWICEAAQVPVVWATQV 409
Query: 396 LESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECV 440
L+ + K+ P+R E+SD + A+CVML+ KG Y +E V
Sbjct: 410 LDQLTKEGLPSRPELSDAVMSA--RAECVMLN----KGPYLLEAV 448
>UniRef50_UPI000155B976 Cluster: PREDICTED: similar to pyruvate
kinase, liver and RBC, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to pyruvate kinase,
liver and RBC, partial - Ornithorhynchus anatinus
Length = 339
Score = 111 bits (268), Expect = 4e-23
Identities = 49/85 (57%), Positives = 67/85 (78%)
Query: 258 LTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALH 317
L +E+GG LGSRKGVN+PG +DLPAVSE+D DL FG++Q VD++FASF+R A +
Sbjct: 55 LVTEVESGGRLGSRKGVNVPGAVLDLPAVSEQDARDLRFGLDQDVDIVFASFVRKAADVA 114
Query: 318 EIRGILGEKGKNIKIISKIENHQGM 342
E+R LG +G+ +K+ISKIENH+G+
Sbjct: 115 EVRAALGPRGRAVKVISKIENHEGV 139
Score = 75.8 bits (178), Expect = 3e-12
Identities = 35/64 (54%), Positives = 43/64 (67%)
Query: 499 SGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSG 558
S +SA LLS+YRPR PI+AVTR + ARQ HL RGV P++Y +P W DVD RVQ
Sbjct: 157 SPRSAQLLSRYRPRAPILAVTRTARAARQAHLCRGVFPLLYPDPPEPVWADDVDRRVQFA 216
Query: 559 LRFG 562
+ G
Sbjct: 217 IDSG 220
>UniRef50_Q8DLH6 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
Pyruvate kinase - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 506
Score = 111 bits (267), Expect = 5e-23
Identities = 99/336 (29%), Positives = 159/336 (47%), Gaps = 29/336 (8%)
Query: 129 MMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGL 188
++ GMN AR+N +H I + R A S G P I +D GP+ R
Sbjct: 160 LLRKGMNCARVNCAHDDPATWEAMIEHLRAA----SHITGQPCK--ILMDLGGPKPRIAD 213
Query: 189 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLIS- 247
+ V + G+ ++LTT E G I ++ G R++IDDG
Sbjct: 214 IF---PETVRVHSGDRLRLTTEI-CPEGGEIPQFTCSLPEIVPQLEVGQRVWIDDGRTGG 269
Query: 248 -IICQSVSADTLTCT-IENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMI 305
I+ + LT T + G L KG+N P + L ++ D+ L F D+I
Sbjct: 270 RIVSKDAQGVELTITHCKEGQRLKVAKGLNFPDSDLRLCPLTASDREHLAFACRYA-DII 328
Query: 306 FASFIRNGAAL----HEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESDG-----IM 356
S++++ + E+ G+ + II+KIE + + L E+I ++ G +M
Sbjct: 329 GYSYVQSAEDIALLQRELAHCCGDCADQMGIIAKIETPKAIRALPEMIIQAAGRQPFGVM 388
Query: 357 VARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANA 416
+ARGDL +EI +++ Q+ ++ C PV+ ATQ+LE++VKK P+RAEI+D A A
Sbjct: 389 IARGDLAVEIGYQRLAEMQEEILWLCEAAHVPVVWATQVLENLVKKGVPSRAEITDAAMA 448
Query: 417 ILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA 452
+ A+CVML+ KG Y V + ++ EA
Sbjct: 449 --ERAECVMLN----KGPYVGLAVDILDDVLARMEA 478
>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 626
Score = 111 bits (266), Expect = 7e-23
Identities = 75/241 (31%), Positives = 126/241 (52%), Gaps = 17/241 (7%)
Query: 221 TIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGSRKGVNL 276
TI + + V PG ++ DDG I + + V D I++ G L + KG+NL
Sbjct: 373 TISCTMPEVVSQVHPGESVWFDDGKIGGVIEKVETDRFWVKIQHARPEGSKLRAGKGMNL 432
Query: 277 PGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGE-KGKNIKIISK 335
P +++ +++ D S L F + + D + SF+ + + + L KG ++ I+ K
Sbjct: 433 PDSQLNVSSLTPTDISHLTF-IAKHADAVQMSFVNSAHDVTLLDEALSRVKGDHLGIVLK 491
Query: 336 IENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVI 390
IE +G NL ++ + G+M+ARGDL +E E++ Q+ +++ C PVI
Sbjct: 492 IETRRGFENLPSMLLTAMRRPKVGVMIARGDLAVECGYERLAEVQEEILSVCEAAHVPVI 551
Query: 391 CATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEA 450
ATQ+LE++ +K P+RAEISD A A+CVML+ KG + +E + + +I K
Sbjct: 552 WATQVLENLAQKGMPSRAEISDAVMA--HRAECVMLN----KGPHVIEALGVLDSILKRM 605
Query: 451 E 451
E
Sbjct: 606 E 606
Score = 41.5 bits (93), Expect = 0.065
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 6/74 (8%)
Query: 119 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 178
++++ +++ +++ GMN R+N +H E E I N + A++ + S + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207
Query: 179 TKGPEIRTGLLEGG 192
GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221
>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
Pyruvate kinase - Mycobacterium sp. (strain JLS)
Length = 615
Score = 110 bits (264), Expect = 1e-22
Identities = 77/244 (31%), Positives = 128/244 (52%), Gaps = 17/244 (6%)
Query: 215 EKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIEN----GGMLGS 270
+ G A I + + +PG +I DDG I +V D L I+ G LGS
Sbjct: 354 DHGGAPRIGCTLPEVFDHARPGEKIRFDDGRIGGEIVAVERDALRVRIDRTAPGGSKLGS 413
Query: 271 RKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKG-KN 329
KGVN+P + + A+++KD DL V D++ SF++ + + ++ L G +
Sbjct: 414 AKGVNVPDTHLPIAALTDKDVEDLATVVAIA-DIVQISFVQRPSDITQLHDELHRLGGDH 472
Query: 330 IKIISKIENHQGMVNLDEIIAESD-----GIMVARGDLGIEIPPEKVFLAQKTMIARCNR 384
+ ++ KIE + +L +++ + G+M+ARGDL +E+ E++ Q+ ++ C
Sbjct: 473 LGVVLKIETRRAFEHLPQLLLTAMRRPRVGVMIARGDLAVEVGYERLAEVQEEVLWLCEA 532
Query: 385 VGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMA 444
PVI ATQ+LES+ K P+RAEISD A + A+CVML+ KG + V+ V +
Sbjct: 533 AHLPVIWATQVLESLAKSGLPSRAEISDAAMG--ERAECVMLN----KGPHIVDAVVVLD 586
Query: 445 NICK 448
+I +
Sbjct: 587 DILR 590
Score = 44.8 bits (101), Expect = 0.007
Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 7/108 (6%)
Query: 86 ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 144
ANVG +L +D+ + R + I+ T+ A+ + ++ ++ GMNVAR+N +H
Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175
Query: 145 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 192
E + R A +S K +A+D GP++RTG + G
Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217
>UniRef50_Q9U016 Cluster: Pyruvate kinase; n=2; Giardia
intestinalis|Rep: Pyruvate kinase - Giardia lamblia
(Giardia intestinalis)
Length = 517
Score = 107 bits (256), Expect = 1e-21
Identities = 111/475 (23%), Positives = 199/475 (41%), Gaps = 34/475 (7%)
Query: 105 SYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAET---IRNCREAEK 161
S R + +I ++GP+ + +M+ G + R+ + S+E + +R C +K
Sbjct: 35 SRYRRAKVIASLGPSCNTEGSIAQMIRHGADAFRIVMAKASNEENIRLYNLVRKCAADQK 94
Query: 162 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 221
+ ++I +GP+ R ++ + L++G + + + E +T
Sbjct: 95 KH---------ISIIASLQGPKFRVTRFRNTTNS-ITLQEGSELNIMFNKA-MECDAPNT 143
Query: 222 IYVDYKNITNVVKPGNRIFIDDGLISIICQSVSADTLTC----TIENGGMLGSRKGVNLP 277
++V+ I V++ G+ + +G + SVS D T L + +P
Sbjct: 144 VFVNESEIFTVIEVGDEVVFKNGPLIAKVTSVSPDKTNVKAVVTTRGSTKLYGGSSLRIP 203
Query: 278 GIPVDLPAVSEKDKSDL-LFGVEQGVDMIFASFIRNGAALHEIRG---ILGEKGKNIK-- 331
+ ++ + L L + VD I S I + + I L +K + +
Sbjct: 204 SKLSSIAPLTSLEYEHLHLLAEKMPVDWICYSHINTESDIKHIENYTDFLSKKYPDFRPM 263
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
+++K+E ++NL +I+ DGIM+ARG LG E+ + QK++I GK
Sbjct: 264 LMTKVETPLAVLNLKQIVTHVDGIMIARGALGDEMDFSYLPSIQKSIIQIARDSGKMCYI 323
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
AT + ESM + PTRAE+SDV N + DG D +L ET+ G + V V + I E
Sbjct: 324 ATNVCESMSENVIPTRAEVSDVTNCLGDGCDGFVLCAETSTGHHSVATVKYLVEIIVAVE 383
Query: 452 ----AVIWHRQLFNDLVSEVKPPIDPXXXXXXXXXXXXTKCLAS-----AIVVITTSGKS 502
V + ++ + +P LAS I + + G
Sbjct: 384 NDPLDVSYRSKVLFSGTTRKQPLKTDSQHRLPDSISVSAISLASILDAKCICIFSIHGGG 443
Query: 503 AHLLSKYRPRCPIIAVTRHPQTARQVHLYRGV-LPIVYQEPTASDWLKDVDNRVQ 556
L + RP P++ +T TAR ++L GV + + ++ D K D VQ
Sbjct: 444 LIRLMRQRPTVPVVVMTAAESTARWMNLLWGVTVNVCHRFTDIEDATKVCDEYVQ 498
>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
bacterium HTCC2170|Rep: Pyruvate kinase -
Flavobacteriales bacterium HTCC2170
Length = 624
Score = 104 bits (250), Expect = 6e-21
Identities = 73/227 (32%), Positives = 115/227 (50%), Gaps = 16/227 (7%)
Query: 234 KPGNRIFIDDGLISIICQSVSADTLTCTI----ENGGMLGSRKGVNLPGIPVDLPAVSEK 289
K G I+ DDG I I + V+A+ + I + G L + KG+NLP + + ++ K
Sbjct: 377 KKGEPIYFDDGKIEGIIEKVTAEDIVVKITHAKDKGSKLKADKGINLPKSDLKISGLTNK 436
Query: 290 DKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEII 349
D+ D+ F + + D + SF+ + + ++ L + I +I KIE +G NL I+
Sbjct: 437 DREDIKF-IAKHADAVNFSFVNSKEDILDLYNELDKLDSKIGVILKIETEKGFSNLPSIL 495
Query: 350 AESD-----GIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPR 404
+ G+M ARGDL IE + Q+ ++ C P I ATQ+LE++ KK
Sbjct: 496 LTAMRSFPIGVMTARGDLAIETGWKNFASIQQEIMRICAAAHIPNIWATQVLENLAKKGT 555
Query: 405 PTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
P+RAEI+D A+ A+CVML+ KG Y V + I + E
Sbjct: 556 PSRAEITDA--ALAQQAECVMLN----KGYYIQRAVKMLDKILRRME 596
Score = 43.6 bits (98), Expect = 0.016
Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 108 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
R + I+ T+ A+ ++ + K++ GMN AR+N +H + E + I N + A K K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190
Query: 167 LGSPFSLAIALDTKGPEIRTG-LLEG 191
IA+D GP++RTG ++EG
Sbjct: 191 C------KIAMDLSGPKLRTGPMVEG 210
>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
(strain A1501)
Length = 625
Score = 104 bits (249), Expect = 8e-21
Identities = 84/287 (29%), Positives = 136/287 (47%), Gaps = 27/287 (9%)
Query: 199 LKKGETIKLTTSS---DYQEKGNADTIYVD--YKNITNVVKPGNRIFIDDGLISIICQSV 253
L+ G+ + LT D NA+T + ++ V G+ ++ DDG I +
Sbjct: 337 LRVGDLLALTADDQPIDPPSNDNAETARIGCTLPHVLAAVAAGDPVWFDDGKIGARVEKA 396
Query: 254 SADTLTCTI------ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFA 307
SAD L I L S KG+N P + + A +E D L F + D++
Sbjct: 397 SADALILRITQIAHASGRAKLASDKGINFPDNALPVRAPTEDDIETLAFAAKHA-DIVQM 455
Query: 308 SFIRNGAALHEIRGILGE-KGKNIKIISKIENHQGMVNLDEIIAESD-----GIMVARGD 361
SF + + E+ L ++ ++ KIE G NL +++ G+M+ARGD
Sbjct: 456 SFANSAEDVIELIDHLERLDATHLGVVLKIETRAGFENLPKMLLAGMRLPRFGVMIARGD 515
Query: 362 LGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGA 421
L +E E++ Q+ M+ C PVI ATQ+LES+ KK P R+EI+D A ++ A
Sbjct: 516 LAVETGFERLAEIQEEMLCLCEAAHVPVIWATQVLESLAKKGAPARSEITDAAMSV--RA 573
Query: 422 DCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEVK 468
+CVML+ KG Y ++ V T+ ++ + HR DL+ ++
Sbjct: 574 ECVMLN----KGPYILKAVTTLNDVLRRMRE---HRAKKRDLLRSLQ 613
Score = 39.9 bits (89), Expect = 0.20
Identities = 24/69 (34%), Positives = 39/69 (56%), Gaps = 6/69 (8%)
Query: 119 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 178
A+ N ++E +++ GM+ AR+N +H + I + R AEK+ LG +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203
Query: 179 TKGPEIRTG 187
GP++RTG
Sbjct: 204 LAGPKLRTG 212
>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 246
Score = 103 bits (248), Expect = 1e-20
Identities = 59/204 (28%), Positives = 104/204 (50%), Gaps = 10/204 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + I+ T+GPA+ + V++K++ G++V R+N SH H+ E R+ ++ ++
Sbjct: 36 RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G + D +GP+IR G + S V L++ L + G+ + + + Y
Sbjct: 96 G------VLCDLQGPKIRIGRFK---SDFVMLEEDGAFILDAECPLTD-GDDERVGLTYP 145
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVS 287
++ N V G+ + +DDG I + V + C + GG L + KG+N G + PA++
Sbjct: 146 DLINDVARGDTLLLDDGAIVLWIAEVEGKQVHCKVVVGGKLSNNKGINKQGGGLSAPALT 205
Query: 288 EKDKSDLLFGVEQGVDMIFASFIR 311
EKDK D+ F E D + SF+R
Sbjct: 206 EKDKQDIKFAAEIDADYLAVSFVR 229
>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
Pyruvate kinase - Geobacillus kaustophilus
Length = 660
Score = 99.5 bits (237), Expect = 2e-19
Identities = 72/231 (31%), Positives = 128/231 (55%), Gaps = 19/231 (8%)
Query: 233 VKPGNRIFIDDGLISIICQSVSADTLTC-TIENGGMLGSRK---GVNLPG--IPVDLPAV 286
V+ G+R++++DG I+ V + + +GG + K G++LP + + +P +
Sbjct: 411 VRAGDRLYLNDGQIAARVVKVHERHVEAKVVADGGKRKAIKQGTGIHLPDSFLHLTVPPL 470
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGK-NIKIISKIENHQGMVNL 345
+++D + F + + D++ SF++ L ++ +L E+G ++ +I+KIE + N
Sbjct: 471 TDRDLEWIPF-IARWADIVGLSFVQAPHDLRKLYHLLAEQGAGSLPVIAKIETRAALHNF 529
Query: 346 DEIIAE-----SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMV 400
I+ E + G+M+ARGDL +EI E + AQ ++A C PVI ATQ+LE M
Sbjct: 530 VRILLEGLKFPAFGVMIARGDLALEIGFEHLAAAQNDVLALCRAAHIPVIWATQVLEQMA 589
Query: 401 KKPRPTRAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
KK P+RAEISDV + A C+ML+ KG + E V ++++ ++ E
Sbjct: 590 KKGIPSRAEISDV--FVGKQAQCIMLN----KGRHIAEAVRLLSSLLEKEE 634
Score = 41.9 bits (94), Expect = 0.049
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Query: 91 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
QL H + S +R + I+ T+ A ++E+++ GM++AR+N ++GS E
Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 201
+ R+AEK +L I +D GP+IR L G ++ +KK
Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265
>UniRef50_Q8FLV7 Cluster: Pyruvate kinase; n=6; Corynebacterium|Rep:
Pyruvate kinase - Corynebacterium efficiens
Length = 630
Score = 98.3 bits (234), Expect = 5e-19
Identities = 84/285 (29%), Positives = 136/285 (47%), Gaps = 33/285 (11%)
Query: 194 SAEVELKKGETIKLTTSSDYQEK----GNADTIYVDYKNITNVVKPGNRIFIDDGLISII 249
S + LK G + LT+ + G I +K G+R+ DDG I+ +
Sbjct: 331 SQRINLKVGNRLFLTSEEVVYDPSAGHGRIPKISCTLPEAVGAIKVGHRVLFDDGSIAAV 390
Query: 250 C--------QSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQG 301
C V +T G L + KG+NLP + LP+++E+D L F V +
Sbjct: 391 CIDRREHDGHHVVELEVTRARPQGVNLAAYKGINLPDSELPLPSLTEEDLRHLRF-VAKH 449
Query: 302 VDMIFASFIRNGA-------ALHEIRGILGEKGK--NIKIISKIENHQGMVNLDEIIA-- 350
D++ SFIR+ AL +I GE K + ++ KIE G NL +I+
Sbjct: 450 ADIVNVSFIRDTGDVEYVLDALAQIAEETGEHDKIRELGLVLKIETIPGYENLAQIMLTG 509
Query: 351 ---ESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
E+ G+M+ARGDL +E+ +++ + ++A P I ATQ+LE+M K P+R
Sbjct: 510 MRHENFGVMIARGDLAVELGFDRMAEVPQLIMALAEAAHIPTIFATQVLENMAKNGLPSR 569
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEA 452
AEI+D A+ +CVML+ KG + + + ++ + K+ A
Sbjct: 570 AEITDATLAL--RCECVMLN----KGPHINDAIKVLSRMSKKLGA 608
>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
braziliensis|Rep: Pyruvate kinase - Leishmania
braziliensis
Length = 91
Score = 97.5 bits (232), Expect = 9e-19
Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 10/99 (10%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 148
SQL H L I +R +G I+CTIGP++++V L+ ++++GM+VARMNFSHGSHEY
Sbjct: 2 SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58
Query: 149 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 187
H TI N R+A +A+LG ++AIALDTKGPEIRTG
Sbjct: 59 HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91
>UniRef50_UPI000049906E Cluster: pyruvate kinase; n=3; Entamoeba
histolytica HM-1:IMSS|Rep: pyruvate kinase - Entamoeba
histolytica HM-1:IMSS
Length = 321
Score = 90.6 bits (215), Expect = 1e-16
Identities = 71/265 (26%), Positives = 133/265 (50%), Gaps = 16/265 (6%)
Query: 175 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVK 234
I +D +G +IR + + L K ++++LT + ++ I++ N ++
Sbjct: 54 IYVDLQGSKIRISRSQ----PNLILTKDQSVELTIKAPTKD---TKAIHIGNPNTIKLLS 106
Query: 235 PGNRIFIDDGLISIICQSVS-ADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSD 293
G + IDDG + I+ S+ ++T T+ GG L KG NL P +SE+D ++
Sbjct: 107 QGTHVKIDDGRMEIVVNSIKDSETAIATVIKGGELKPGKGFNLQPHPFVQNQLSERD-AE 165
Query: 294 LLFGVEQGVDMIFA-SFIRNGAALHEIRGILGEKGKNIK-IISKIENHQGMVNLDEIIAE 351
++ ++ ++ FA SF+ + EI+ + +K N K I++KIE + L I ++
Sbjct: 166 IVEKLKDVKEVCFALSFV---CVVEEIQDL--KKRSNGKYIVAKIEREMDLERLKAISSQ 220
Query: 352 SDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
+ I + RGD+G+++ + + ++ P I A +++E + PTR+EI
Sbjct: 221 CNEIWICRGDMGVQLGFVGMAKFVREYTTFMKQLNCPSIMAGEVMEHLCDNTIPTRSEIC 280
Query: 412 DVANAILDGADCVMLSGETAKGDYP 436
+ N I DG + ++LS ET G YP
Sbjct: 281 YLGNLIADGYNGIVLSDETVFGKYP 305
>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
(Blood fluke)
Length = 168
Score = 89.0 bits (211), Expect = 3e-16
Identities = 44/136 (32%), Positives = 80/136 (58%), Gaps = 4/136 (2%)
Query: 90 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 149
S +QH+ ID ++R + ++CT+G + +++M+++GMN+ R+N S G+ E +
Sbjct: 25 SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84
Query: 150 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 209
AE IR R E+SY +P S+ IALD P +RTGL+ A V ++ G+ + LT
Sbjct: 85 AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140
Query: 210 SSDYQEKGNADTIYVD 225
+ +Y++ + I+++
Sbjct: 141 NDEYEKNTTSSIIWIN 156
>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=4; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 123
Score = 88.6 bits (210), Expect = 4e-16
Identities = 44/89 (49%), Positives = 62/89 (69%), Gaps = 3/89 (3%)
Query: 92 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 151
L+HMC L+IDS +GIICTIG ++V +L+ M+ +GMNVA +NFSHG+HEYHAE
Sbjct: 27 LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83
Query: 152 TIRNCREAEKSYSAKLGSPFSLAIALDTK 180
TI+N +S+++ S+ +ALDTK
Sbjct: 84 TIKNVCATTESFASDPILYLSIVVALDTK 112
>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
wickerhamii|Rep: Pyruvate kinase - Prototheca
wickerhamii
Length = 259
Score = 83.4 bits (197), Expect = 2e-14
Identities = 53/147 (36%), Positives = 84/147 (57%), Gaps = 12/147 (8%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 167
R + +CTIGP S + ++ + GMNV R+N SHG H H + I RE Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154
Query: 168 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYK 227
G +LAI LDTKGPE+R+G L + ++L+KG+ I T + G + I V+Y
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFTIVAG--ADGTNNRIGVNYD 207
Query: 228 NITNVVKPGNRIFIDDGLISIICQSVS 254
+ V+ G+ + +D G+++++ +S S
Sbjct: 208 GFIDDVEVGDMLLVDGGIMTMLVKSKS 234
>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium berghei|Rep: Putative uncharacterized protein
- Plasmodium berghei
Length = 158
Score = 81.8 bits (193), Expect = 5e-14
Identities = 47/123 (38%), Positives = 69/123 (56%), Gaps = 11/123 (8%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
I+CT+GPA ++V L ++++ GM++ R NFSHG+H+ H + N +A+
Sbjct: 41 IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94
Query: 172 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITN 231
+L + LD KGPEIRTGLL G+ E LK+G +KL +DY G+ I Y T
Sbjct: 95 TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLV--ADYSYLGDETCIACSYTKCTT 149
Query: 232 VVK 234
K
Sbjct: 150 KCK 152
>UniRef50_Q676G7 Cluster: Pyruvate kinase; n=1; Agrobacterium
tumefaciens|Rep: Pyruvate kinase - Agrobacterium
tumefaciens
Length = 334
Score = 70.5 bits (165), Expect = 1e-10
Identities = 72/264 (27%), Positives = 124/264 (46%), Gaps = 12/264 (4%)
Query: 175 IALDTKGPEIRTGLLEGGGSAEVELKKGE--TIKLTTSSDYQEKGNADTIYVDYKNITNV 232
I +D G + RTG + G AE+ LKKGE T+ LT S + G T + +
Sbjct: 57 IFVDLPGNKARTGNIPG---AELYLKKGERLTLSLTEPSAEIDLGTM-TFGLSRPELFGN 112
Query: 233 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKS 292
VK G+ + DG + + +TC + G++ + GV V+ +S+ D
Sbjct: 113 VKTGSSVSFRDGAAIAQITEATPEKITCVVTRPGVICTSCGVVPVEGYVEYKTLSDIDVI 172
Query: 293 DLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAES 352
+L + + V I SF + + +++ I + +I II+KIE+ + NL I S
Sbjct: 173 -ILGMIPEYVFGINVSFADSAIIIRQVKSIC--RFDHINIIAKIESKIAVDNLIGINEAS 229
Query: 353 DGIMVARGDLGIEIPPEKVF-LAQKTMIARCNRVGKPVICATQMLESMVKKPRPTRAEIS 411
DG+++ARGDLG + V +A K + R + G P+I AT K + +E +
Sbjct: 230 DGLILARGDLGNFYDEQSVINIAHKIVELRPFQAG-PIIFATNYFTEPAKGLALSTSEQA 288
Query: 412 DVANAILDGADCVMLSGETAKGDY 435
+ A G + ++++ ET+ +
Sbjct: 289 TIQEAFKLGVNTILVN-ETSSSQH 311
>UniRef50_Q8MR79 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
Pyruvate kinase - Drosophila melanogaster (Fruit fly)
Length = 659
Score = 64.1 bits (149), Expect = 1e-08
Identities = 50/182 (27%), Positives = 84/182 (46%), Gaps = 6/182 (3%)
Query: 133 GMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG----L 188
G+ +N G+ + I REAE S S +LG P + ++ + TG
Sbjct: 175 GVRCFMVNLFEGTQHDNQSLIVKLREAEISVSKELGFPVTSSVMVKISPRHQFTGGFSTQ 234
Query: 189 LEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISI 248
G VEL +G+ + LT Y ++ NAD IYV+ + + V P + I I + I +
Sbjct: 235 FRQEGKKCVELVQGQKVILTVDRQYSDRSNADVIYVNARFLIVDVHPLDFILIGED-IQL 293
Query: 249 ICQSVSADTLTCTIENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFGVEQGVDMIFAS 308
+ +S+ AD L + GGML + V P +S ++ DL F E G++++ +
Sbjct: 294 MVRSIHADHLKGCVARGGMLYAHMPVLFPA-RCRRFRISYEELEDLTFAREVGLNVVVSH 352
Query: 309 FI 310
+
Sbjct: 353 IV 354
Score = 34.7 bits (76), Expect = 7.5
Identities = 22/97 (22%), Positives = 42/97 (43%)
Query: 490 ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLK 549
A AIVVI + + +S +RP PI+ V+ V +Y V + ++ +
Sbjct: 524 AVAIVVIGVTTRMVQKISHFRPHAPILFVSHMRSAEDYVSIYHNVTMLPFRTKCIIAHRR 583
Query: 550 DVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGF 586
+V + L + +R D ++V ++ G+ F
Sbjct: 584 NVFLKAIYALAYLVKRKIAKQNDQVILVYNYEDGTKF 620
>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
citri|Rep: Pyruvate kinase - Spiroplasma citri
Length = 192
Score = 64.1 bits (149), Expect = 1e-08
Identities = 34/73 (46%), Positives = 44/73 (60%), Gaps = 6/73 (8%)
Query: 112 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 171
II TIGP++ + +E++ +TGM R+NFSHG H I RE SAK+G P
Sbjct: 15 IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70
Query: 172 SLAIALDTKGPEI 184
S + LDTKGPEI
Sbjct: 71 S--VLLDTKGPEI 81
>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
vinelandii AvOP
Length = 165
Score = 60.5 bits (140), Expect = 1e-07
Identities = 36/104 (34%), Positives = 58/104 (55%), Gaps = 5/104 (4%)
Query: 492 AIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDV 551
AIV +T SG + L+S+ R PI A +RHP+T +V L+RGV PI P +D + +
Sbjct: 62 AIVCLTESGDTPRLMSRIRSHLPIYAFSRHPRTQSRVALFRGVHPI----PFEADRIAEA 117
Query: 552 DNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVMLV 595
+ ++ ++ QR V GD ++ G G T+T+R++ V
Sbjct: 118 ELNARA-VKELLQRRLVAEGDRVLITKGAGHAQGGTDTLRIVRV 160
Score = 40.7 bits (91), Expect = 0.11
Identities = 18/51 (35%), Positives = 29/51 (56%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 158
R + I+ T+G A+ +E +++ G++V R+NFSHG E H RE
Sbjct: 3 RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53
>UniRef50_P46614 Cluster: Pyruvate kinase; n=1; Candida
albicans|Rep: Pyruvate kinase - Candida albicans (Yeast)
Length = 92
Score = 54.0 bits (124), Expect = 1e-05
Identities = 28/69 (40%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Query: 208 TTSSDYQEKGNADTIYVDYKNITNVVKPGNRIFIDDGLISIICQSV-SADTLTCTIENGG 266
TT Y+ K + + +DYKNIT V+ PG I++DDG++S SV TL N G
Sbjct: 12 TTDDAYKTKCDDKVMIIDYKNITKVIAPGKIIYVDDGVLSFEVISVDDQQTLKVRSLNAG 71
Query: 267 MLGSRKGVN 275
M+ S K N
Sbjct: 72 MISSHKTAN 80
>UniRef50_A4BH87 Cluster: Pyruvate kinase; n=1; Reinekea sp.
MED297|Rep: Pyruvate kinase - Reinekea sp. MED297
Length = 123
Score = 48.8 bits (111), Expect = 4e-04
Identities = 38/103 (36%), Positives = 50/103 (48%), Gaps = 8/103 (7%)
Query: 493 IVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVD 552
IVV T GKS + KY PR I+A+TR +TA+ + L +GV + EP S D
Sbjct: 28 IVVATEHGKSVKSVRKYFPRAQILALTRSTKTAQHLCLTKGV-TTSHVEPFESS-----D 81
Query: 553 NRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVMLV 595
+ + Q G GD VVV G S TNTV V ++
Sbjct: 82 SLYEKAKEKALQYGLAKSGDTIVVVAGALFES--TNTVSVQII 122
>UniRef50_Q2Y8W2 Cluster: Pyruvate kinase; n=1; Nitrosospira
multiformis ATCC 25196|Rep: Pyruvate kinase -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 107
Score = 48.0 bits (109), Expect = 7e-04
Identities = 27/104 (25%), Positives = 56/104 (53%), Gaps = 3/104 (2%)
Query: 490 ASAIVVITTSGKSAHLLSKYRPRCPIIAVTRHPQTARQVHLYRGVLPIVYQEPTASDWLK 549
A A+VV S +A ++++RP+ PI+A+T R + L + P++ E A+ +
Sbjct: 3 ARAVVVFVQSVAAALEVARFRPQLPIVAITGSAMLYRSLALAHAIAPLLCAECNATAEPR 62
Query: 550 DVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVM 593
++ + + L+ +G PGD V++TG + G +T++++
Sbjct: 63 NLITKAGAWLQV---QGLARPGDEVVLLTGSQTTDGKLDTLQIV 103
>UniRef50_A5BYI4 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
Pyruvate kinase - Vitis vinifera (Grape)
Length = 314
Score = 44.4 bits (100), Expect = 0.009
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 8/164 (4%)
Query: 263 ENGGMLGSRKGVNLPGIPVDLPAVSEKDKSDLLFG--VEQGVDMIFASFIRNGAALHEIR 320
E+G +LG VNL V+L +DLL G E + R+ +
Sbjct: 85 ESGKLLGQPSKVNL----VELGPGQRTVMTDLLCGDNTEVSTQELEMCERRHSQWKCRSK 140
Query: 321 GILGEKGKNIKIISKIENHQGMVNLDEIIAESDGIMVARG-DLGIEIPPEKVFLAQKTMI 379
GILG + I + +V D + A+ G + G D+ +P
Sbjct: 141 GILGFPQLS-GTADTIHKNVSLVKSDPVHAKVKGGSLVNGLDIQQSMPSTASHARTSRSG 199
Query: 380 ARCNRVGKPVICATQMLESMVKKPRPTRAEISDVANAILDGADC 423
+ + I ATQML S++K P R + +D+ANA+L G+DC
Sbjct: 200 ENQTQNYRKAITATQMLGSIIKSLCPVRVKATDIANAVLGGSDC 243
>UniRef50_A7QZT2 Cluster: Chromosome chr13 scaffold_286, whole
genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome chr13 scaffold_286, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 292
Score = 43.2 bits (97), Expect = 0.021
Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 6/93 (6%)
Query: 432 KGDYPVECVHTMANICKEAEAVIWHRQLFND------LVSEVKPPIDPXXXXXXXXXXXX 485
+GD H MAN +++ ++FN V V P+
Sbjct: 111 EGDRNTGFFHRMANAHHRNNSLVRAEKVFNQDFYFKKAVKHVGEPMTHLESIASSAVRAA 170
Query: 486 TKCLASAIVVITTSGKSAHLLSKYRPRCPIIAV 518
AS IV T++GK+A L+ KYRP P+I+V
Sbjct: 171 ISVKASVIVCFTSTGKAARLIGKYRPTMPVISV 203
>UniRef50_A7QZ91 Cluster: Chromosome undetermined scaffold_267,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_267, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 314
Score = 43.2 bits (97), Expect = 0.021
Identities = 29/110 (26%), Positives = 53/110 (48%), Gaps = 5/110 (4%)
Query: 160 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNA 219
+K++ + F +AI +DT+G EI G L SA+ E GE I + + +
Sbjct: 184 KKAFLTEQEKGFVVAIMMDTEGSEIHMGELGSAPSAKTE--DGE-IWIFSVQTFDSPRPE 240
Query: 220 DTIYVDYKNITNVVKPGNRIFIDDGLISI-ICQSVSADTLTCTIENGGML 268
TI ++Y VK G+ + +D G++ + + + D + C + G+L
Sbjct: 241 STININYDGFAEDVKVGDELLVDSGMVRFDVIEKIGPD-VKCRCTDPGLL 289
>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
ATCC BAA-548
Length = 121
Score = 42.7 bits (96), Expect = 0.028
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 18/133 (13%)
Query: 107 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 166
++ + I+ TI ++ +L + + GM+V R+N +H + R+
Sbjct: 1 MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56
Query: 167 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYVDY 226
LAI +DTKGP IRT L+ A + LK G+ + LT + QEK + V+Y
Sbjct: 57 ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLTGETVPQEK----AVQVNY 102
Query: 227 KNITNVVKPGNRI 239
T V G RI
Sbjct: 103 SKFTAEVPVGARI 115
>UniRef50_Q9VVH0 Cluster: CG12229-PA; n=2; Sophophora|Rep:
CG12229-PA - Drosophila melanogaster (Fruit fly)
Length = 571
Score = 42.3 bits (95), Expect = 0.037
Identities = 100/487 (20%), Positives = 192/487 (39%), Gaps = 56/487 (11%)
Query: 125 VLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS-----------YSAKLGSPFSL 173
V + + ET + R +G++ +H +T+ N + K+ +SA+ +
Sbjct: 78 VAKLVTETTHDELRRMLENGTYTFHVDTVGNKPDELKAILDTMNIAISAHSAERELRLTT 137
Query: 174 AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIYV-DYKNITNV 232
+AL+ G R G L + V L +G + LTT Y+ KG + +YV + +
Sbjct: 138 GLALEINGECCRVGRLRN--NCTVMLARGGVVTLTTDESYRYKGFKEIVYVINLRCYLAS 195
Query: 233 VKPGNRIFIDDGLISIICQSVSADTLTCTIENGGMLGSRKGVNLPG--IPVDLPAVSEKD 290
V+ G+ + I + + +++ + LT I + G++ S + LP +D +
Sbjct: 196 VQLGDIVMIGREVRGKVVKTL-REALTVMIIDAGLVASYDFIELPRQCHALDPDLYPDLY 254
Query: 291 KSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIE---NHQGMVNLDE 347
DL + + IR + L +R L N+K+I I+ M++L
Sbjct: 255 MKDLEMAASLNANYVVLPKIRCKSFLRAVRQTL-NSDFNLKLIGMIDFEYVRSNMLDLLG 313
Query: 348 IIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPTR 407
II D I + + + I++C + KPVI T LE + R
Sbjct: 314 IIKLVDYIWIP-DMFNVNCCVYNYIMEDVLPISQCQK--KPVI-GTVPLE---RCSDFKR 366
Query: 408 AEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAEAVIWHRQLFNDLVSEV 467
E+ D L D + + YP+ V + I + ++ + +++
Sbjct: 367 FELHD----FLWKVDAIHIQKSPWCNKYPL-IVKKLMPIKDYRVGAVQNKMVLKSILTSY 421
Query: 468 KPPIDPXXXXXXXXXXXXTKCLASAIVVITTSGKSAHLLSKYRPRCPII----------- 516
+ ++ +C AI + TT ++ LS+ CP+
Sbjct: 422 QTIVN-----FIIRTISSIEC--QAIFLFTTCETASVALSRIEIYCPVYVMVPLEETDDA 474
Query: 517 -AVTRHPQTARQVHLYRGVLPIVYQEPTASDWLKDVDNRVQSGLRFGRQRGFVHPGDNAV 575
+T + AR +HL R + P++Y D + + ++ G+ F R++G + GD V
Sbjct: 475 ETITCKVELARALHLRRNMHPVLY----TKDLNECSYSPIEFGVDFMRKKGCLEVGDFVV 530
Query: 576 VVTGWKQ 582
+ K+
Sbjct: 531 TLEVGKE 537
>UniRef50_Q4JN61 Cluster: CG7362-PA; n=1; uncultured bacterium
BAC13K9BAC|Rep: CG7362-PA - uncultured bacterium
BAC13K9BAC
Length = 254
Score = 39.1 bits (87), Expect = 0.35
Identities = 43/165 (26%), Positives = 75/165 (45%), Gaps = 14/165 (8%)
Query: 287 SEKDKSDLLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLD 346
S+ DK + FG E + I + I NG L + I + GKNIK +++ LD
Sbjct: 83 SDIDKY-IAFGKEISPE-IMSFDISNG--LDFFKTIKSKLGKNIKTCVRVKLGTSTEGLD 138
Query: 347 EIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVICATQMLESMVKKPRPT 406
+ E D M IE+ KV K ++ + + +P+ A ++ +++K +
Sbjct: 139 DFFKECDYSM-------IELD-SKVIHDDKIVMRSKDNMCEPIYLA--LMPTLMKGQVQS 188
Query: 407 RAEISDVANAILDGADCVMLSGETAKGDYPVECVHTMANICKEAE 451
R E ++ + + +G D + L ET+ G Y V + I E+E
Sbjct: 189 REENFEIGHTLEEGFDLIALYQETSHGPYAARSVKCIDEISVESE 233
>UniRef50_Q3ZYI6 Cluster: Transcription-repair coupling factor; n=3;
Dehalococcoides|Rep: Transcription-repair coupling
factor - Dehalococcoides sp. (strain CBDB1)
Length = 1148
Score = 38.7 bits (86), Expect = 0.46
Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 8/95 (8%)
Query: 492 AIVVITTSGKSAHLLSKYRP-RCPIIAVTRHPQTAR----QVHLYRGVLPIVYQEPTASD 546
A + + +G+ L + YR +CP++ +T P+ AR Q+ Y G P +P+
Sbjct: 28 ADISVLDAGRGFSLAAVYRKLKCPMLVITSQPERARELLEQIAAYSGEEPGFLPDPSLLP 87
Query: 547 WLKDVDNRVQS--GLRF-GRQRGFVHPGDNAVVVT 578
+ + V +R S +R G GF+ GD ++VT
Sbjct: 88 YQRAVSDRNSSLEKMRLAGILGGFIRSGDARIIVT 122
>UniRef50_UPI00006CB055 Cluster: hypothetical protein
TTHERM_00239360; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00239360 - Tetrahymena
thermophila SB210
Length = 1220
Score = 37.1 bits (82), Expect = 1.4
Identities = 19/66 (28%), Positives = 34/66 (51%)
Query: 162 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADT 221
S S + + F+ LDT GP + + ++++K E+IK+ + YQ KGN+
Sbjct: 924 SKSQQNSNQFNQGNQLDTLGPFENNAVQNSLENISLKIEKNESIKIQSKDIYQNKGNSQF 983
Query: 222 IYVDYK 227
+ +D K
Sbjct: 984 LNIDQK 989
>UniRef50_A0IJJ4 Cluster: HpcH/HpaI aldolase; n=2; Bacteria|Rep:
HpcH/HpaI aldolase - Serratia proteamaculans 568
Length = 287
Score = 36.3 bits (80), Expect = 2.4
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 294 LLFGVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQGMVNLDEIIAESD 353
+L G I S +R+ A + +R GK+ +I IE + + +LD++ A +D
Sbjct: 85 MLCGGGTAPGFIVMSMVRSPAEVVFLRETFASAGKHPEIYLTIETVEAITDLDDVAAVAD 144
Query: 354 GIMVARGD----LGIEIPPEKVFLAQKTMIARCNRVG 386
G++ D LG+ I + A++ M+ R G
Sbjct: 145 GLIFGSADLAATLGVPITWSGMLAARQAMVLASARHG 181
>UniRef50_A0V3R8 Cluster: S-layer-like region; n=1; Clostridium
cellulolyticum H10|Rep: S-layer-like region -
Clostridium cellulolyticum H10
Length = 1382
Score = 35.5 bits (78), Expect = 4.3
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 175 IALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDYQEKGNADTIY-VDYKNI--TN 231
I ++ ++R +L+G E+E+ KGE I +T S E D I V NI T
Sbjct: 243 IKIEKNNNKLRIVILDGNTVKEIEIAKGEEIIVTGSVGTLEIATPDVIVKVIAANISDTK 302
Query: 232 VVKPGNRIFID-DGLISIICQSVSADTLTCTIENGGMLGS 270
VV IF+D + I + + SA+ E G ++ +
Sbjct: 303 VVSANASIFVDKESKIKSVSINNSAENTAIKAEKGAVVNT 342
>UniRef50_Q54CD8 Cluster: Putative RNA helicase; n=2; Dictyostelium
discoideum|Rep: Putative RNA helicase - Dictyostelium
discoideum AX4
Length = 1091
Score = 35.5 bits (78), Expect = 4.3
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 288 EKDKSDLLF-GVEQGVDMIFASFIRNGAALHEIRGILGEKGKNIKIISKIENHQ-GMVNL 345
+K S ++F + V+ I R G A I G L + I + +K +HQ G++ +
Sbjct: 495 QKKSSTIIFVSTKYHVEFIHILLERAGIASTYIHGYLDPVARKINL-AKFRSHQVGVMVV 553
Query: 346 DEIIAESDGIMVARGDLGIEIPP-EKVFLAQKTMIARCNRVG 386
++ A I + + + PP EK+F+ + +AR R G
Sbjct: 554 TDLAARGIDIPLLDNVINFDFPPKEKIFIHRVGRVARAGRSG 595
>UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor,
serine/threonine protein kinase; n=1; Methanocorpusculum
labreanum Z|Rep: Putative anti-sigma regulatory factor,
serine/threonine protein kinase - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 777
Score = 35.1 bits (77), Expect = 5.6
Identities = 17/48 (35%), Positives = 25/48 (52%)
Query: 97 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 144
G ID K +YI+ SG+IC G A + V +KM G + ++ G
Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396
>UniRef50_A6G647 Cluster: SNF2/helicase domain protein; n=1;
Plesiocystis pacifica SIR-1|Rep: SNF2/helicase domain
protein - Plesiocystis pacifica SIR-1
Length = 1056
Score = 34.7 bits (76), Expect = 7.5
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 546 DWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGF 586
D L +D R + GL FG+ RG V D A V+ W+ G GF
Sbjct: 475 DDLHPLDARARLGLGFGK-RGRVRRADAAAVLRAWRAGEGF 514
>UniRef50_Q4CYW8 Cluster: Putative uncharacterized protein; n=3;
Trypanosoma|Rep: Putative uncharacterized protein -
Trypanosoma cruzi
Length = 435
Score = 34.7 bits (76), Expect = 7.5
Identities = 36/144 (25%), Positives = 60/144 (41%), Gaps = 7/144 (4%)
Query: 108 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA--EKSYSA 165
R+SG++ T+ P + A+ E + +A + +H E HA+ C A E+ S+
Sbjct: 30 RVSGLLFTVNPRQESKALRELQLYLHPLIADLEEAHKRVEEHADARGRCDNATTEEQSSS 89
Query: 166 KLGSPFSLAIALDTK---GPEIRTGLLEGGGSAEVELKK--GETIKLTTSSDYQEKGNAD 220
K+ + IA T E+ + GG E+++ + K S D EK + D
Sbjct: 90 KMSTDAGGKIAPSTSSLLAAELAEYITTRGGQRRHEMRRIPMKEEKSDVSDDEDEKKSTD 149
Query: 221 TIYVDYKNITNVVKPGNRIFIDDG 244
+ N +N NR D G
Sbjct: 150 NNNNNNNNNSNNNILRNRSSDDGG 173
>UniRef50_UPI00005082DC Cluster: PREDICTED: similar to Pyruvate
kinase isozyme M2; n=1; Rattus norvegicus|Rep:
PREDICTED: similar to Pyruvate kinase isozyme M2 -
Rattus norvegicus
Length = 137
Score = 34.3 bits (75), Expect = 9.9
Identities = 23/50 (46%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 546 DWLKDVDNRVQSGLRFGRQRGFVHPGDNAVVVTGWKQGSGFTNTVRVMLV 595
D L+DVD RV + GFV GD V+TGW+ SGFT+T V+ V
Sbjct: 94 DALQDVDLRVNLAMN----GGFVKKGD---VLTGWRPVSGFTSTKCVVPV 136
>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
subunit ClpA; n=1; Shewanella baltica OS223|Rep:
ATP-dependent Clp protease, ATP-binding subunit ClpA -
Shewanella baltica OS223
Length = 66
Score = 34.3 bits (75), Expect = 9.9
Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
Query: 159 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 205
AEK Y +G+ P + + K P EI G+LE GG A V++K+GE +
Sbjct: 3 AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53
>UniRef50_Q9SZT8 Cluster: Putative uncharacterized protein F6G17.30;
n=2; core eudicotyledons|Rep: Putative uncharacterized
protein F6G17.30 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 632
Score = 34.3 bits (75), Expect = 9.9
Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 26 LSRRGIQFFTRKGSSRSRKPPVSRNRELTDKYLHYNPLKMVYPTIHDGEIEAGAVEKPTV 85
L GI+ F G KP + L LK Y TI + ++A +V +V
Sbjct: 376 LVNEGIRIFESMGQEYGIKPKIEHYGCLVSLLGRAGQLKRAYETIKNMNMDADSVLWSSV 435
Query: 86 AN---------VGSQL-QHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGM- 134
+G ++ +++ GL+I + Y+ LS I ++G V M E G+
Sbjct: 436 LGSCKLHGDFVLGKEIAEYLIGLNIKNSGIYVLLSNIYASVGDYEGVAKVRNLMKEKGIV 495
Query: 135 ---NVARMNFSHGSHEYHA 150
++ + + HE+ A
Sbjct: 496 KEPGISTIEIENKVHEFRA 514
>UniRef50_A3LQY4 Cluster: Predicted protein; n=1; Pichia
stipitis|Rep: Predicted protein - Pichia stipitis
(Yeast)
Length = 1931
Score = 34.3 bits (75), Expect = 9.9
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 332 IISKIENHQGMVNLDEIIAESDGIMVARGDLGIEIPPEKVFLAQKTMIARCNRVGKPVIC 391
+IS+ ++ +DE+I + DG++ G +EIP E KT + ++ +PV+
Sbjct: 767 VISERATNESKSRVDEVIVDGDGVIEEEGLCRLEIPNE------KTEMEELEKIERPVL- 819
Query: 392 ATQMLESMVKKPRPTRAEISDVANAILDGADCVMLSGE 429
E +R E S V A+ DG D V+ S E
Sbjct: 820 EELATEEEDYTESDSRFEFSGV-EAVEDGNDEVVASHE 856
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.319 0.135 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 665,048,311
Number of Sequences: 1657284
Number of extensions: 27145568
Number of successful extensions: 62644
Number of sequences better than 10.0: 189
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 61927
Number of HSP's gapped (non-prelim): 249
length of query: 623
length of database: 575,637,011
effective HSP length: 105
effective length of query: 518
effective length of database: 401,622,191
effective search space: 208040294938
effective search space used: 208040294938
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 75 (34.3 bits)
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