Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002494-TA|BGIBMGA002494-PA|IPR000719|Protein kinase,
IPR008271|Serine/threonine protein kinase, active site,
IPR002290|Serine/threonine protein kinase, IPR011009|Protein
kinase-like, IPR011029|DEATH-like
(598 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 154 1e-36
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 154 1e-36
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 154 1e-36
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 154 1e-36
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 154 1e-36
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 147 1e-34
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 128 7e-29
BC069388-1|AAH69388.1| 596|Homo sapiens interleukin-1 receptor-... 104 8e-22
BC057800-1|AAH57800.1| 596|Homo sapiens interleukin-1 receptor-... 104 8e-22
AF113136-1|AAD40879.1| 596|Homo sapiens IL-1 receptor-associate... 104 8e-22
L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1 receptor-as... 101 7e-21
BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein. 101 7e-21
AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor ... 101 7e-21
AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1 receptor-... 101 7e-21
DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor ... 96 4e-19
BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1 receptor-... 96 4e-19
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 86 3e-16
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 84 1e-15
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 84 1e-15
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 84 1e-15
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 82 6e-15
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 82 6e-15
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 81 8e-15
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 81 8e-15
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 81 8e-15
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 81 8e-15
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 81 8e-15
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 81 8e-15
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 81 8e-15
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 81 8e-15
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 81 8e-15
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 81 1e-14
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 80 2e-14
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 80 2e-14
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 80 2e-14
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 80 2e-14
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 80 2e-14
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 80 2e-14
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 80 2e-14
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 80 2e-14
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 80 2e-14
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 80 2e-14
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 80 2e-14
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 80 2e-14
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 80 2e-14
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 80 3e-14
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 80 3e-14
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 80 3e-14
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 80 3e-14
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 80 3e-14
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 80 3e-14
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 80 3e-14
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 80 3e-14
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 80 3e-14
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 79 4e-14
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 79 4e-14
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 79 4e-14
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 79 4e-14
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 79 4e-14
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 79 4e-14
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 79 4e-14
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 79 4e-14
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 79 4e-14
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 79 4e-14
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 79 4e-14
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 79 6e-14
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 79 6e-14
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 79 6e-14
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 79 6e-14
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 79 6e-14
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 78 8e-14
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 78 8e-14
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 78 8e-14
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 78 8e-14
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 78 8e-14
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 78 8e-14
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 78 1e-13
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 77 1e-13
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 77 2e-13
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 77 2e-13
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 77 2e-13
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 77 2e-13
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 77 2e-13
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 76 3e-13
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 76 3e-13
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 76 3e-13
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 76 3e-13
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 76 3e-13
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 75 5e-13
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 75 5e-13
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 75 1e-12
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 75 1e-12
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 75 1e-12
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 75 1e-12
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 75 1e-12
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 75 1e-12
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 74 1e-12
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 74 1e-12
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 74 1e-12
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 74 1e-12
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 74 1e-12
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 74 1e-12
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 74 1e-12
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 74 1e-12
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 74 1e-12
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 74 1e-12
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 74 1e-12
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 73 3e-12
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 73 3e-12
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 73 3e-12
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 73 3e-12
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 73 3e-12
X63128-1|CAA44839.1| 513|Homo sapiens activin receptor protein. 73 4e-12
X62381-1|CAA44245.1| 513|Homo sapiens activin receptor protein. 73 4e-12
M93415-1|AAA35504.1| 513|Homo sapiens activin type II receptor ... 73 4e-12
BC069707-1|AAH69707.1| 513|Homo sapiens activin A receptor, typ... 73 4e-12
BC067418-1|AAH67418.1| 513|Homo sapiens activin A receptor, typ... 73 4e-12
BC067417-1|AAH67417.1| 513|Homo sapiens activin A receptor, typ... 73 4e-12
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 73 4e-12
AC009480-2|AAX93050.1| 513|Homo sapiens unknown protein. 73 4e-12
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 72 5e-12
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 72 5e-12
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 72 5e-12
AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 72 5e-12
AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 72 5e-12
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 72 5e-12
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 72 5e-12
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 72 5e-12
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 72 5e-12
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 72 5e-12
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 72 5e-12
AK091708-1|BAC03728.1| 471|Homo sapiens protein ( Homo sapiens ... 72 5e-12
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 72 5e-12
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 72 5e-12
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 72 5e-12
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 72 5e-12
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 72 7e-12
BC125184-1|AAI25185.1| 625|Homo sapiens interleukin-1 receptor-... 72 7e-12
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 72 7e-12
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 72 7e-12
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 72 7e-12
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 72 7e-12
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 72 7e-12
AJ496794-1|CAD43180.3| 625|Homo sapiens interleukin-1 receptor ... 72 7e-12
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 72 7e-12
AF026273-1|AAB87669.1| 590|Homo sapiens interleukin-1 receptor-... 72 7e-12
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 72 7e-12
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 72 7e-12
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 71 9e-12
AK027291-1|BAB55019.1| 322|Homo sapiens protein ( Homo sapiens ... 71 9e-12
AF237709-1|AAF71521.1| 322|Homo sapiens spermatogenesis-related... 71 9e-12
AF189722-1|AAF69107.1| 322|Homo sapiens PDZ-binding kinase prot... 71 9e-12
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 71 1e-11
D31770-1|BAA06548.1| 513|Homo sapiens activin typeII A receptor... 71 1e-11
BC015191-1|AAH15191.1| 322|Homo sapiens PDZ binding kinase prot... 71 1e-11
AB027250-1|BAA99577.1| 322|Homo sapiens MPAKK-like protein kina... 71 1e-11
AB027249-1|BAA99576.1| 322|Homo sapiens MAPKK like protein kina... 71 1e-11
X77533-1|CAA54671.1| 512|Homo sapiens activin type II receptor ... 70 2e-11
BC099642-1|AAH99642.1| 512|Homo sapiens activin A receptor, typ... 70 2e-11
BC096245-1|AAH96245.1| 303|Homo sapiens ACVR2B protein protein. 70 2e-11
BC096244-1|AAH96244.1| 512|Homo sapiens activin A receptor, typ... 70 2e-11
BC096243-1|AAH96243.1| 512|Homo sapiens activin A receptor, typ... 70 2e-11
AB209449-1|BAD92686.1| 514|Homo sapiens activin A type IIB rece... 70 2e-11
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 70 3e-11
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 70 3e-11
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 70 3e-11
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 70 3e-11
AF060202-1|AAC64515.1| 512|Homo sapiens activin receptor type I... 70 3e-11
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 70 3e-11
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 70 3e-11
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 70 3e-11
AB008681-1|BAA24180.2| 512|Homo sapiens activin receptor type I... 70 3e-11
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 69 4e-11
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 69 4e-11
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 69 4e-11
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 69 4e-11
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 69 4e-11
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 69 4e-11
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 69 4e-11
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 69 5e-11
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 69 5e-11
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 69 5e-11
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 69 5e-11
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 69 5e-11
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 69 5e-11
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 69 5e-11
Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine pro... 69 6e-11
DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated prote... 69 6e-11
BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated prote... 69 6e-11
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 68 8e-11
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 68 8e-11
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 68 8e-11
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 68 8e-11
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 68 1e-10
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 68 1e-10
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 68 1e-10
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 68 1e-10
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 68 1e-10
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 68 1e-10
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 68 1e-10
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 68 1e-10
AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4 ... 67 1e-10
AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4 ... 67 1e-10
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 67 2e-10
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 67 2e-10
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 67 2e-10
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 67 2e-10
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 67 2e-10
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 67 2e-10
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 67 2e-10
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 66 3e-10
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 66 3e-10
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 66 3e-10
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 66 3e-10
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 66 3e-10
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 66 3e-10
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 66 3e-10
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 66 3e-10
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 66 3e-10
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 66 3e-10
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 66 3e-10
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 66 3e-10
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4b... 66 3e-10
AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase 4a... 66 3e-10
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 66 3e-10
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 66 3e-10
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 66 3e-10
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 66 3e-10
Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewin... 66 4e-10
D14497-1|BAA03387.1| 467|Homo sapiens proto-oncogene protein pr... 66 4e-10
CR542284-1|CAG47079.1| 467|Homo sapiens MAP3K8 protein. 66 4e-10
BC113566-1|AAI13567.1| 467|Homo sapiens mitogen-activated prote... 66 4e-10
BC104833-1|AAI04834.1| 467|Homo sapiens mitogen-activated prote... 66 4e-10
AY309013-1|AAP45053.1| 467|Homo sapiens mitogen-activated prote... 66 4e-10
AL161651-12|CAI14227.1| 467|Homo sapiens mitogen-activated prot... 66 4e-10
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 65 6e-10
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 65 6e-10
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 65 6e-10
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 65 8e-10
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 65 8e-10
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 65 8e-10
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 65 8e-10
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 65 8e-10
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 65 8e-10
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 65 8e-10
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 65 8e-10
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 65 8e-10
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 65 8e-10
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 65 8e-10
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 65 8e-10
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 65 8e-10
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 65 8e-10
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 65 8e-10
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 65 8e-10
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 65 8e-10
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 65 8e-10
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 65 8e-10
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 65 8e-10
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 64 1e-09
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 64 1e-09
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 64 1e-09
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 64 1e-09
BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein. 64 1e-09
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 64 1e-09
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 64 1e-09
AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2 p... 64 1e-09
AB004884-1|BAA20561.1| 719|Homo sapiens PKU-alpha protein. 64 1e-09
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 64 2e-09
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 64 2e-09
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 64 2e-09
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 64 2e-09
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 64 2e-09
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 64 2e-09
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 64 2e-09
BC023017-1|AAH23017.1| 618|Homo sapiens NPR2 protein protein. 64 2e-09
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 64 2e-09
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 64 2e-09
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 64 2e-09
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 64 2e-09
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 64 2e-09
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 64 2e-09
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 64 2e-09
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 64 2e-09
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 64 2e-09
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 64 2e-09
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
AL133410-13|CAI10987.1| 1047|Homo sapiens natriuretic peptide re... 64 2e-09
AJ005282-1|CAA06466.1| 995|Homo sapiens NPR-Bi protein. 64 2e-09
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 64 2e-09
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 64 2e-09
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 64 2e-09
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 64 2e-09
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 64 2e-09
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 64 2e-09
Z22535-1|CAA80257.1| 532|Homo sapiens ALK-3 protein. 63 2e-09
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 63 2e-09
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 63 2e-09
BC028383-1|AAH28383.1| 532|Homo sapiens bone morphogenetic prot... 63 2e-09
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 63 2e-09
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 63 2e-09
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 63 2e-09
AB005647-1|BAA81737.1| 1047|Homo sapiens atrial natriuretic pept... 63 2e-09
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 63 3e-09
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 63 3e-09
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 63 3e-09
U89326-1|AAC28131.1| 502|Homo sapiens bone morphogenetic protei... 62 4e-09
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 62 4e-09
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 62 4e-09
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 62 4e-09
D89675-1|BAA19765.1| 502|Homo sapiens bone morphogenetic protei... 62 4e-09
BC069803-1|AAH69803.1| 502|Homo sapiens bone morphogenetic prot... 62 4e-09
BC069796-1|AAH69796.1| 502|Homo sapiens bone morphogenetic prot... 62 4e-09
BC047773-1|AAH47773.1| 502|Homo sapiens BMPR1B protein protein. 62 4e-09
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 62 4e-09
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 62 5e-09
D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein. 62 5e-09
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 62 5e-09
BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1 p... 62 5e-09
AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SN... 62 5e-09
AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1 p... 62 5e-09
AC010092-1|AAY15077.1| 376|Homo sapiens unknown protein. 62 5e-09
U69152-1|AAB40916.1| 567|Homo sapiens transforming growth facto... 62 7e-09
U52246-1|AAB17553.1| 567|Homo sapiens transforming growth facto... 62 7e-09
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 62 7e-09
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 62 7e-09
M85079-1|AAA61164.1| 567|Homo sapiens TGF-beta type II receptor... 62 7e-09
DQ377559-1|ABG65632.1| 567|Homo sapiens transforming growth fac... 62 7e-09
AY675319-1|AAT70724.1| 567|Homo sapiens transforming growth fac... 62 7e-09
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 62 7e-09
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 62 7e-09
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 62 7e-09
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 62 7e-09
AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein. 62 7e-09
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 61 9e-09
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 61 9e-09
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 61 9e-09
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 61 9e-09
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 61 9e-09
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 61 9e-09
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 61 9e-09
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 61 9e-09
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 61 9e-09
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 61 9e-09
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 61 9e-09
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 61 9e-09
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 61 9e-09
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 61 9e-09
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 61 9e-09
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 61 9e-09
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 61 9e-09
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 61 1e-08
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 61 1e-08
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 60 2e-08
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 60 2e-08
D50683-1|BAA09332.1| 567|Homo sapiens TGF-betaIIR alpha protein. 60 3e-08
BC004553-1|AAH04553.1| 540|Homo sapiens receptor-interacting se... 60 3e-08
AY524045-1|AAS94254.1| 540|Homo sapiens GIG30 protein. 60 3e-08
AY358814-1|AAQ89173.1| 540|Homo sapiens RIPK2 protein. 60 3e-08
AF078530-1|AAC27722.1| 540|Homo sapiens receptor interacting pr... 60 3e-08
AF064824-1|AAC25668.1| 540|Homo sapiens CARD-containing ICE ass... 60 3e-08
AF027706-1|AAC34970.1| 540|Homo sapiens serine/threonine kinase... 60 3e-08
AC004003-1|AAC24561.1| 540|Homo sapiens WUGSC:H_RG437L15.1 prot... 60 3e-08
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 59 4e-08
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 59 4e-08
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 59 4e-08
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 59 4e-08
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 59 4e-08
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 59 4e-08
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 59 4e-08
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 59 5e-08
X79483-1|CAA55984.1| 367|Homo sapiens extracellular signal regu... 59 5e-08
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 59 5e-08
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 59 5e-08
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 59 5e-08
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 59 5e-08
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 59 5e-08
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 59 5e-08
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 58 7e-08
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 58 7e-08
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 58 7e-08
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 58 7e-08
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 58 9e-08
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 58 9e-08
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 58 9e-08
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 58 9e-08
DQ445915-1|ABE03013.1| 435|Homo sapiens mitogen-activated prote... 58 9e-08
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 58 9e-08
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 58 9e-08
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 58 9e-08
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 58 9e-08
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 58 9e-08
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 58 9e-08
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 58 9e-08
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 58 9e-08
AF022805-1|AAC26142.1| 419|Homo sapiens c-Jun N-terminal kinase... 58 9e-08
AF014401-1|AAB88048.1| 419|Homo sapiens JNK kinase 2 protein. 58 9e-08
AF006689-1|AAB97813.1| 401|Homo sapiens Jnkk2 protein. 58 9e-08
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 58 1e-07
U66243-1|AAB40118.1| 367|Homo sapiens p38gamma MAP Kinase protein. 58 1e-07
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 58 1e-07
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 58 1e-07
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 58 1e-07
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 58 1e-07
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 58 1e-07
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 58 1e-07
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 58 1e-07
BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting se... 58 1e-07
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 58 1e-07
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 58 1e-07
AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting pr... 58 1e-07
AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 58 1e-07
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 58 1e-07
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 58 1e-07
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 58 1e-07
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 57 2e-07
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 57 2e-07
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 57 2e-07
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 57 2e-07
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 57 2e-07
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 57 2e-07
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 57 2e-07
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 57 2e-07
Y10487-1|CAA71511.1| 367|Homo sapiens stress-activated protein ... 57 2e-07
U17743-1|AAC50127.1| 399|Homo sapiens JNK activating kinase pro... 57 2e-07
L36870-1|AAC41719.1| 399|Homo sapiens MAP kinase kinase 4 protein. 57 2e-07
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 57 2e-07
DQ015703-1|AAY22176.1| 399|Homo sapiens mitogen-activated prote... 57 2e-07
CR536564-1|CAG38801.1| 399|Homo sapiens MAP2K4 protein. 57 2e-07
BT019676-1|AAV38482.1| 399|Homo sapiens mitogen-activated prote... 57 2e-07
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
BC060764-1|AAH60764.1| 399|Homo sapiens mitogen-activated prote... 57 2e-07
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 57 2e-07
BC036032-1|AAH36032.1| 399|Homo sapiens mitogen-activated prote... 57 2e-07
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 57 2e-07
BC015741-1|AAH15741.1| 367|Homo sapiens mitogen-activated prote... 57 2e-07
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 57 2e-07
AL022328-12|CAB51538.1| 367|Homo sapiens mitogen-activated prot... 57 2e-07
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 57 2e-07
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 57 2e-07
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 57 2e-07
AF070090-1|AAC24130.1| 399|Homo sapiens mitogen-activated prote... 57 2e-07
U38894-1|AAC50714.1| 388|Homo sapiens tyrosine kinase t-Ror1 pr... 56 3e-07
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 56 3e-07
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 56 3e-07
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 56 3e-07
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 56 3e-07
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 56 3e-07
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 56 3e-07
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 56 3e-07
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 56 3e-07
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 56 3e-07
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 56 3e-07
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 56 3e-07
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 56 3e-07
AF013589-1|AAC16273.1| 462|Homo sapiens mitogen-activated prote... 56 3e-07
AF013588-1|AAC16272.1| 419|Homo sapiens mitogen-activated prote... 56 3e-07
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 55 6e-07
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 55 6e-07
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 55 6e-07
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 55 6e-07
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 55 6e-07
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 55 6e-07
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 55 8e-07
U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein. 55 8e-07
U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein. 55 8e-07
L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein. 55 8e-07
D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b prot... 55 8e-07
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 55 8e-07
CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein. 55 8e-07
CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein. 55 8e-07
>BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor
associated kinase-4 protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 4
protein.
Length = 336
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 30 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 85
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 86 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 143
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 144 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 188
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 189 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 248
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 249 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 307
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 308 VASQCLHEKKNKRPDIKKVQQLLQEM 333
>AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 3
protein.
Length = 336
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 30 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 85
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 86 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 143
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 144 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 188
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 189 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 248
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 249 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 307
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 308 VASQCLHEKKNKRPDIKKVQQLLQEM 333
>AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 2
protein.
Length = 336
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 30 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 85
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 86 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 143
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 144 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 188
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 189 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 248
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 249 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 307
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 308 VASQCLHEKKNKRPDIKKVQQLLQEM 333
>AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 1
protein.
Length = 336
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 30 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 85
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 86 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 143
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 144 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 188
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 189 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 248
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 249 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 307
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 308 VASQCLHEKKNKRPDIKKVQQLLQEM 333
>AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 variant protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens
cDNA FLJ20521 fis, clone KAT10395. ).
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor
associated kinase 4 protein.
Length = 460
Score = 154 bits (373), Expect = 1e-36
Identities = 104/326 (31%), Positives = 172/326 (52%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
+A +CL + ++ RP I +V + L++M
Sbjct: 432 VASQCLHEKKNKRPDIKKVQQLLQEM 457
Score = 40.7 bits (91), Expect = 0.014
Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ T L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTAGDLVDLLIQNEFFAPA 97
>AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase
NY-REN-64 antigen protein.
Length = 460
Score = 147 bits (356), Expect = 1e-34
Identities = 102/326 (31%), Positives = 169/326 (51%), Gaps = 33/326 (10%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 154 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 209
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 210 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 267
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 268 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 312
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 313 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 372
Query: 502 FGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLD--MVVERWTRAQGIYE 559
FG+VLLE++TGL P V + + D E++ +E K I +D M T + +Y
Sbjct: 373 FGVVLLEIITGL-PAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYS 431
Query: 560 LAKRCLSDNRDNRPSIDEVCETLEKM 585
A +C + ++ P I +V + L++M
Sbjct: 432 GASQCRHEKKNKSPDIKKVHQLLQEM 457
Score = 42.3 bits (95), Expect = 0.005
Identities = 28/98 (28%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 4 NTELRKLPMGSLYNIINILEINDSWQKVMAWIPTNPQSDHFHRKYNSEHLRMIQDDAKIS 63
+T +R L +G + + + ++ + W+K+ I P D +YN H+R + +
Sbjct: 8 STYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIK-KPSGDD---RYNQFHIRRFEALLQTG 63
Query: 64 KRTCSEILFDEWSTSGRIRPTVATLLDVLVKAEIYRAA 101
K SE+LFD W T+ TV L+D+L++ E + A
Sbjct: 64 KSPTSELLFD-WGTT---NCTVGDLVDLLIQNEFFAPA 97
>AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens
cDNA FLJ14395 fis, clone HEMBA1003250, weakly similar to
PROTEIN KINASE APK1A (EC 2.7.1.-). ).
Length = 277
Score = 128 bits (308), Expect = 7e-29
Identities = 84/255 (32%), Positives = 136/255 (53%), Gaps = 30/255 (11%)
Query: 271 DSKILE--DENLISFDYNQLAAITNNFSEDLNEXXXXXXXXXXXXXXXEVFVGTHNRYGQ 328
++K LE D SF + +L +TNNF E V+ G N
Sbjct: 30 ENKSLEVSDTRFHSFSFYELKNVTNNFDE---RPISVGGNKMGEGGFGVVYKGYVNNT-T 85
Query: 329 LAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDG 388
+AVKK+ + + + F+ E+K +++ +H+N+V + G+S DG C+V Y+
Sbjct: 86 VAVKKLAAMVDITTEE--LKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPN 143
Query: 389 GSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDV 444
GSL+++++ L+ + R +I G A G+ ++H +IH D+
Sbjct: 144 GSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHEN---------------HHIHRDI 188
Query: 445 KSANILLTKDCKPMLCDFGLAKQLES---TRVTSMMMGTSAYMPPEAIKGTLTKKTDVYS 501
KSANILL + + DFGLA+ E T +TS ++GT+AYM PEA++G +T K+D+YS
Sbjct: 189 KSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYS 248
Query: 502 FGIVLLELLTGLKPI 516
FG+VLLE++TGL +
Sbjct: 249 FGVVLLEIITGLPAV 263
>BC069388-1|AAH69388.1| 596|Homo sapiens interleukin-1
receptor-associated kinase 3 protein.
Length = 596
Score = 104 bits (250), Expect = 8e-22
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 29/249 (11%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAA----KVLNENQRL 406
F +E++ L H NI+ + Y + C++ Y+ G+L +++ L + R+
Sbjct: 209 FLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRI 268
Query: 407 EIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA- 465
I+ G ++ + Y+HN V+P V I G + SANILL +P L DF +A
Sbjct: 269 GILIGISKAIHYLHN-VQPCSV-----------ICGSISSANILLDDQFQPKLTDFAMAH 316
Query: 466 --KQLESTRVTSMMMGTSA----YMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVV 518
LE T M +S+ YMP E I+ G L+ KTDVYSFGIV++E+LTG + +V+
Sbjct: 317 FRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCR-VVL 375
Query: 519 DSNGNLNIKDYVEQVMNEN--KDITQLLDMVVERWTR--AQGIYELAKRCLSDNRDNRPS 574
D ++ ++D + ++M + LD V R + ++ LA RC + RPS
Sbjct: 376 DDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPS 435
Query: 575 IDEVCETLE 583
+DEV TLE
Sbjct: 436 MDEVLNTLE 444
>BC057800-1|AAH57800.1| 596|Homo sapiens interleukin-1
receptor-associated kinase 3 protein.
Length = 596
Score = 104 bits (250), Expect = 8e-22
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 29/249 (11%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAA----KVLNENQRL 406
F +E++ L H NI+ + Y + C++ Y+ G+L +++ L + R+
Sbjct: 209 FLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRI 268
Query: 407 EIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA- 465
I+ G ++ + Y+HN V+P V I G + SANILL +P L DF +A
Sbjct: 269 GILIGISKAIHYLHN-VQPCSV-----------ICGSISSANILLDDQFQPKLTDFAMAH 316
Query: 466 --KQLESTRVTSMMMGTSA----YMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVV 518
LE T M +S+ YMP E I+ G L+ KTDVYSFGIV++E+LTG + +V+
Sbjct: 317 FRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCR-VVL 375
Query: 519 DSNGNLNIKDYVEQVMNEN--KDITQLLDMVVERWTR--AQGIYELAKRCLSDNRDNRPS 574
D ++ ++D + ++M + LD V R + ++ LA RC + RPS
Sbjct: 376 DDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPS 435
Query: 575 IDEVCETLE 583
+DEV TLE
Sbjct: 436 MDEVLNTLE 444
>AF113136-1|AAD40879.1| 596|Homo sapiens IL-1
receptor-associated-kinase-M protein.
Length = 596
Score = 104 bits (250), Expect = 8e-22
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 29/249 (11%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAA----KVLNENQRL 406
F +E++ L H NI+ + Y + C++ Y+ G+L +++ L + R+
Sbjct: 209 FLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRI 268
Query: 407 EIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA- 465
I+ G ++ + Y+HN V+P V I G + SANILL +P L DF +A
Sbjct: 269 GILIGISKAIHYLHN-VQPCSV-----------ICGSISSANILLDDQFQPKLTDFAMAH 316
Query: 466 --KQLESTRVTSMMMGTSA----YMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVV 518
LE T M +S+ YMP E I+ G L+ KTDVYSFGIV++E+LTG + +V+
Sbjct: 317 FRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCR-VVL 375
Query: 519 DSNGNLNIKDYVEQVMNEN--KDITQLLDMVVERWTR--AQGIYELAKRCLSDNRDNRPS 574
D ++ ++D + ++M + LD V R + ++ LA RC + RPS
Sbjct: 376 DDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPS 435
Query: 575 IDEVCETLE 583
+DEV TLE
Sbjct: 436 MDEVLNTLE 444
>L76191-1|AAC41949.1| 712|Homo sapiens interleukin-1
receptor-associated kinase protein.
Length = 712
Score = 101 bits (242), Expect = 7e-21
Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 29/202 (14%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 256 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 315
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 316 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 362
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 363 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
Query: 515 PIVVDSNGNLNIKDYVEQVMNE 536
+ +KD VE+ E
Sbjct: 423 AVKTHGARTKYLKDLVEEEAEE 444
>BC054000-1|AAH54000.1| 693|Homo sapiens IRAK1 protein protein.
Length = 693
Score = 101 bits (242), Expect = 7e-21
Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 29/202 (14%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 282 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 341
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 342 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 388
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 389 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 448
Query: 515 PIVVDSNGNLNIKDYVEQVMNE 536
+ +KD VE+ E
Sbjct: 449 AVKTHGARTKYLKDLVEEEAEE 470
>AF346607-1|AAK62888.1| 682|Homo sapiens interleukin-1 receptor
associated kinase 1b protein.
Length = 682
Score = 101 bits (242), Expect = 7e-21
Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 29/202 (14%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 256 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 315
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 316 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 362
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 363 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
Query: 515 PIVVDSNGNLNIKDYVEQVMNE 536
+ +KD VE+ E
Sbjct: 423 AVKTHGARTKYLKDLVEEEAEE 444
>AF030876-1|AAC08756.1| 712|Homo sapiens Interleukin 1
receptor-associated kinase 1 protein.
Length = 712
Score = 101 bits (242), Expect = 7e-21
Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 29/202 (14%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 256 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 315
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 316 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 362
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 363 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
Query: 515 PIVVDSNGNLNIKDYVEQVMNE 536
+ +KD VE+ E
Sbjct: 423 AVKTHGARTKYLKDLVEEEAEE 444
>DQ054788-1|AAY88246.1| 633|Homo sapiens interleukin-1 receptor
associated-kinase 1 splice variant c protein.
Length = 633
Score = 95.9 bits (228), Expect = 4e-19
Identities = 67/182 (36%), Positives = 94/182 (51%), Gaps = 29/182 (15%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 256 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 315
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 316 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 362
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 363 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
Query: 515 PI 516
+
Sbjct: 423 AV 424
>BC014963-1|AAH14963.1| 633|Homo sapiens interleukin-1
receptor-associated kinase 1 protein.
Length = 633
Score = 95.9 bits (228), Expect = 4e-19
Identities = 67/182 (36%), Positives = 94/182 (51%), Gaps = 29/182 (15%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-----AAKVLNENQR 405
F EV+ LS+ RH NIV GY C+V ++ GSL +++ A L+ QR
Sbjct: 256 FLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQR 315
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
L+I+ GTA ++++H SP IHGD+KS+N+LL + P L DFGLA
Sbjct: 316 LDILLGTARAIQFLHQD----------SPSL---IHGDIKSSNVLLDERLTPKLGDFGLA 362
Query: 466 K----------QLESTRVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLK 514
+ Q T + GT AY+P E IK G L TD +SFG+V+LE L G +
Sbjct: 363 RFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQR 422
Query: 515 PI 516
+
Sbjct: 423 AV 424
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 86.2 bits (204), Expect = 3e-16
Identities = 57/171 (33%), Positives = 88/171 (51%), Gaps = 18/171 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
++K L +L+H NI+ G P CI+ +Y G L E + A + + ++ +G
Sbjct: 204 DIKHLRKLKHPNIIAFKGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGI 263
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A G+ Y+H + I IH D+KS N+L+T + DFG +K+L
Sbjct: 264 ASGMNYLH--LHKI-------------IHRDLKSPNVLVTHTDAVKISDFGTSKELSDKS 308
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIV-VDSN 521
GT A+M PE I+ +++K D++SFG+VL ELLTG P VDS+
Sbjct: 309 TKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSS 359
>U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein
kinase protein.
Length = 859
Score = 84.2 bits (199), Expect = 1e-15
Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 18/175 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEI 408
L ++K L +L+H NI+ G P CI+ ++ G L E + A + + + ++
Sbjct: 157 LKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW 216
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL 468
G A G+ Y+H + I IH D+KS N+L+T D + DFG +K+L
Sbjct: 217 SMGIAGGMNYLH-----------LHKI----IHRDLKSPNMLITYDDVVKISDFGTSKEL 261
Query: 469 ESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIV-VDSN 521
GT A+M PE I+ +++K D++SFG+VL ELLTG P VDS+
Sbjct: 262 SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSS 316
>BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein.
Length = 567
Score = 84.2 bits (199), Expect = 1e-15
Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 18/175 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEI 408
L ++K L +L+H NI+ G P CI+ ++ G L E + A + + + ++
Sbjct: 190 LKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW 249
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL 468
G A G+ Y+H + I IH D+KS N+L+T D + DFG +K+L
Sbjct: 250 SMGIAGGMNYLH-----------LHKI----IHRDLKSPNMLITYDDVVKISDFGTSKEL 294
Query: 469 ESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIV-VDSN 521
GT A+M PE I+ +++K D++SFG+VL ELLTG P VDS+
Sbjct: 295 SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSS 349
>AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase
protein.
Length = 859
Score = 84.2 bits (199), Expect = 1e-15
Identities = 58/175 (33%), Positives = 90/175 (51%), Gaps = 18/175 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEI 408
L ++K L +L+H NI+ G P CI+ ++ G L E + A + + + ++
Sbjct: 157 LKETDIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDW 216
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL 468
G A G+ Y+H + I IH D+KS N+L+T D + DFG +K+L
Sbjct: 217 SMGIAGGMNYLH-----------LHKI----IHRDLKSPNMLITYDDVVKISDFGTSKEL 261
Query: 469 ESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIV-VDSN 521
GT A+M PE I+ +++K D++SFG+VL ELLTG P VDS+
Sbjct: 262 SDKSTKMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSS 316
>Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase with
SH3 domain, leucine zipper domain and proline rich
protein.
Length = 953
Score = 81.8 bits (193), Expect = 6e-15
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 6/163 (3%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + L+H NI+ + G ++ P C+V +Y GG+L +A + + + + A
Sbjct: 145 EARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVA 204
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV 473
G+ Y+HN ++ D+ I + +++ N+ D + DFGLA++ T
Sbjct: 205 RGMNYLHNDAPVPIIHRDLKSINILILEA-IENHNL---ADTVLKITDFGLAREWHKTTK 260
Query: 474 TSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
S GT A+M PE I+ +L +K +DV+SFG++L ELLTG P
Sbjct: 261 MS-AAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVP 302
>X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2
protein.
Length = 954
Score = 81.8 bits (193), Expect = 6e-15
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 6/163 (3%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + L+H NI+ + G ++ P C+V +Y GG+L +A + + + + A
Sbjct: 145 EARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVA 204
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV 473
G+ Y+HN ++ D+ I + +++ N+ D + DFGLA++ T
Sbjct: 205 RGMNYLHNDAPVPIIHRDLKSINILILEA-IENHNL---ADTVLKITDFGLAREWHKTTK 260
Query: 474 TSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
S GT A+M PE I+ +L +K +DV+SFG++L ELLTG P
Sbjct: 261 MS-AAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVP 302
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I +
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELAKGEPP 218
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 81.0 bits (191), Expect = 1e-14
Identities = 73/247 (29%), Positives = 118/247 (47%), Gaps = 28/247 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAI--KGTLT-KKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
SM + GT AY+PPE I K L+ K DVYSF IV+ +LT KP + NI
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLSDTKHDVYSFAIVIWGVLTQKKPFADEK----NI 229
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMI 586
+ +V+ ++ +L + R + L +RC + RP+ E+ E +
Sbjct: 230 LHIMVKVVKGHR--PELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLC 287
Query: 587 NQESYEI 593
+ E+
Sbjct: 288 EKPDDEV 294
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 80.2 bits (189), Expect = 2e-14
Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 28/247 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAIK---GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
SM + GT AY+PPE I+ K DVYSF IV+ +LT KP + NI
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEK----NI 229
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMI 586
+ +V+ ++ +L + R + L +RC + RP+ E+ E +
Sbjct: 230 LHIMVKVVKGHR--PELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLC 287
Query: 587 NQESYEI 593
+ E+
Sbjct: 288 EKPDDEV 294
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 80.2 bits (189), Expect = 2e-14
Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 28/247 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAIK---GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
SM + GT AY+PPE I+ K DVYSF IV+ +LT KP + NI
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEK----NI 229
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMI 586
+ +V+ ++ +L + R + L +RC + RP+ E+ E +
Sbjct: 230 LHIMVKVVKGHR--PELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLC 287
Query: 587 NQESYEI 593
+ E+
Sbjct: 288 EKPDDEV 294
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 49 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 104
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 105 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 152
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 153 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 210 SKADIWSLGITAIELARGEPP 230
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 49 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 104
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 105 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 152
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 153 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 210 SKADIWSLGITAIELARGEPP 230
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 80.2 bits (189), Expect = 2e-14
Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 28/247 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAIK---GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
SM + GT AY+PPE I+ K DVYSF IV+ +LT KP + NI
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEK----NI 229
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMI 586
+ +V+ ++ +L + R + L +RC + RP+ E+ E +
Sbjct: 230 LHIMVKVVKGHR--PELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLC 287
Query: 587 NQESYEI 593
+ E+
Sbjct: 288 EKPDDEV 294
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 49 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 104
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 105 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 152
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 153 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 209
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 210 SKADIWSLGITAIELARGEPP 230
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/201 (29%), Positives = 94/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 80.2 bits (189), Expect = 2e-14
Identities = 71/247 (28%), Positives = 116/247 (46%), Gaps = 28/247 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAIK---GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
SM + GT AY+PPE I+ K DVYSF IV+ +LT KP + NI
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEK----NI 229
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMI 586
+ +V+ ++ +L + R + L +RC + RP+ E+ E +
Sbjct: 230 LHIMVKVVKGHR--PELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLC 287
Query: 587 NQESYEI 593
+ E+
Sbjct: 288 EKPDDEV 294
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 79.8 bits (188), Expect = 3e-14
Identities = 77/273 (28%), Positives = 136/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 261 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 313
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 314 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMVFIE------ERN---- 362
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 363 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 417
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N+ E + N + +V
Sbjct: 418 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTNL----EVIQNLERGY-----RMVRP 465
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 466 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 498
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 590 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 649
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 650 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 696
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 697 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLLWMAPEVFTQCTRYTIKADVFSYALCL 756
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 757 WEILTGEIP 765
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 489 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 548
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 549 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 595
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 596 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 655
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 656 WEILTGEIP 664
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 79.8 bits (188), Expect = 3e-14
Identities = 60/189 (31%), Positives = 92/189 (48%), Gaps = 20/189 (10%)
Query: 334 VKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTP-CIVCKYIDGGSLM 392
+K Y Y + +F EV L QL H ++ G ++ P+ IV +YI GGSL
Sbjct: 595 IKRYRANTYCSKSDVDMFCREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLF 654
Query: 393 EKI--AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL 450
+ ++L+ +L I A+G++Y+HN +PI IH D+ S NIL
Sbjct: 655 SLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPI-------------IHRDLNSHNIL 701
Query: 451 LTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK--GTLTKKTDVYSFGIVL 506
L +D ++ DFG ++ L+S +M G +M PE T K DV+S+ + L
Sbjct: 702 LYEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCL 761
Query: 507 LELLTGLKP 515
E+LTG P
Sbjct: 762 WEILTGEIP 770
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppressor
gene-4 protein protein.
Length = 312
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 98 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 157
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 158 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 204
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 205 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 259
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 260 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 312
Query: 590 S 590
S
Sbjct: 313 S 313
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 79.0 bits (186), Expect = 4e-14
Identities = 69/241 (28%), Positives = 110/241 (45%), Gaps = 29/241 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---S 410
E + LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ +
Sbjct: 53 EAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWAT 112
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
A+G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 113 DVAKGMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHN 159
Query: 471 TRVTSMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDY 529
++GT +M PE I+ +T D YS+G+VL E+LT P L
Sbjct: 160 HTTHMSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQV 214
Query: 530 VEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQE 589
V+ +N+ +T + R+ EL +C + RPS ++ LE M N
Sbjct: 215 AWLVVEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDT 267
Query: 590 S 590
S
Sbjct: 268 S 268
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 258 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 310
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 311 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---- 359
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 360 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 414
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N E + N + +V
Sbjct: 415 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRP 462
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 463 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 258 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 310
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 311 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---- 359
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 360 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 414
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N E + N + +V
Sbjct: 415 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRP 462
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 463 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 258 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 310
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 311 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---- 359
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 360 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 414
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N E + N + +V
Sbjct: 415 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRP 462
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 463 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 495
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 245 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 297
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 298 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---- 346
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 347 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 401
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N E + N + +V
Sbjct: 402 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRP 449
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 450 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 482
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/273 (28%), Positives = 135/273 (49%), Gaps = 41/273 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 245 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 297
Query: 377 PTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P I+ +Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N
Sbjct: 298 PI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---- 346
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK- 490
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI
Sbjct: 347 -----YIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY 401
Query: 491 GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVER 550
GT T K+DV+SFGI+L E++T + + G N E + N + +V
Sbjct: 402 GTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRP 449
Query: 551 WTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ +Y+L + C + ++RP+ D + LE
Sbjct: 450 DNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 482
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 495 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 553
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 554 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 598
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 599 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 656
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 657 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 710
Query: 579 CETLE 583
++E
Sbjct: 711 LASIE 715
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 57 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 115
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 116 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 160
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 161 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 218
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 219 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 272
Query: 579 CETLE 583
++E
Sbjct: 273 LASIE 277
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 495 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 553
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 554 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 598
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 599 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 656
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 657 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 710
Query: 579 CETLE 583
++E
Sbjct: 711 LASIE 715
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 495 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 553
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 554 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 598
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 599 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 656
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 657 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 710
Query: 579 CETLE 583
++E
Sbjct: 711 LASIE 715
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 1221 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 1279
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 1280 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 1324
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 1325 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 1382
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 1383 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 1436
Query: 579 CETLE 583
++E
Sbjct: 1437 LASIE 1441
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 78.2 bits (184), Expect = 8e-14
Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 33/245 (13%)
Query: 348 IRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKVLNENQR 405
++ F EV L + RH NI+ GYS P IV ++ +G SL I +
Sbjct: 380 LQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKL 438
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
++I TA+G+ Y+H K I IH D+KS NI L +D + DFGLA
Sbjct: 439 IDIARQTAQGMDYLH--AKSI-------------IHRDLKSNNIFLHEDLTVKIGDFGLA 483
Query: 466 ---KQLESTRVTSMMMGTSAYMPPEAI----KGTLTKKTDVYSFGIVLLELLTGLKPIVV 518
+ + + G+ +M PE I K + ++DVY+FGIVL EL+TG P
Sbjct: 484 TVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPY-- 541
Query: 519 DSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEV 578
N+N +D + ++ ++ L V +A + L CL RD RP ++
Sbjct: 542 ---SNINNRDQIIFMVGRGY-LSPDLSKVRSNCPKA--MKRLMAECLKKKRDERPLFPQI 595
Query: 579 CETLE 583
++E
Sbjct: 596 LASIE 600
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/201 (29%), Positives = 93/201 (46%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR ++ K+ + D I E+ LSQ + +G +
Sbjct: 37 EVFKGIDNRTQKVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYVTKYYGSYLKD 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K
Sbjct: 93 TKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ + L D G+A QL T++ + +GT +M PE IK
Sbjct: 141 ---IHRDIKAANVLLSEHGEVKLADIGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 197
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 198 SKADIWSLGITAIELARGEPP 218
>AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein.
Length = 400
Score = 77.4 bits (182), Expect = 1e-13
Identities = 68/237 (28%), Positives = 108/237 (45%), Gaps = 29/237 (12%)
Query: 358 LSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII---SGTAE 414
LS L H+NI+ +G ++ P IV +Y GSL + I + E I+ + A+
Sbjct: 4 LSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAK 63
Query: 415 GLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVT 474
G+ Y+H P++V IH D+KS N+++ D +CDFG A + +
Sbjct: 64 GMHYLHMEA-PVKV-----------IHRDLKSRNVVIAADGVLKICDFG-ASRFHNHTTH 110
Query: 475 SMMMGTSAYMPPEAIKGTLTKKT-DVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQV 533
++GT +M PE I+ +T D YS+G+VL E+LT P L V
Sbjct: 111 MSLVGTFPWMAPEVIQSLPVSETCDTYSYGVVLWEMLTREVPF-----KGLEGLQVAWLV 165
Query: 534 MNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLEKMINQES 590
+ +N+ +T + R+ EL +C + RPS ++ LE M N S
Sbjct: 166 VEKNERLT-----IPSSCPRS--FAELLHQCWEADAKKRPSFKQIISILESMSNDTS 215
>BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein.
Length = 1104
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/171 (31%), Positives = 89/171 (52%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + L+H NI+ + G + P C+V ++ GG L ++ K + + + A
Sbjct: 191 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 250
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H+ + PI IH D+KS+NIL+ + + + DFGLA
Sbjct: 251 RGMNYLHDEA--------IVPI----IHRDLKSSNILILQKVENGDLSNKILKITDFGLA 298
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE I+ ++ +K +DV+S+G++L ELLTG P
Sbjct: 299 REWHRTTKMSAA-GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP 348
>BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein.
Length = 1103
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/171 (31%), Positives = 89/171 (52%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + L+H NI+ + G + P C+V ++ GG L ++ K + + + A
Sbjct: 190 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 249
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H+ + PI IH D+KS+NIL+ + + + DFGLA
Sbjct: 250 RGMNYLHDEA--------IVPI----IHRDLKSSNILILQKVENGDLSNKILKITDFGLA 297
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE I+ ++ +K +DV+S+G++L ELLTG P
Sbjct: 298 REWHRTTKMSAA-GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP 347
>AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein
kinase 1 protein.
Length = 1104
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/171 (31%), Positives = 89/171 (52%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + L+H NI+ + G + P C+V ++ GG L ++ K + + + A
Sbjct: 191 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 250
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H+ + PI IH D+KS+NIL+ + + + DFGLA
Sbjct: 251 RGMNYLHDEA--------IVPI----IHRDLKSSNILILQKVENGDLSNKILKITDFGLA 298
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE I+ ++ +K +DV+S+G++L ELLTG P
Sbjct: 299 REWHRTTKMSAA-GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP 348
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 77.0 bits (181), Expect = 2e-13
Identities = 59/175 (33%), Positives = 89/175 (50%), Gaps = 22/175 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + + + I+P++G + P +V +Y++ GSL + +A++ L + R II TA
Sbjct: 69 EAKKMEMAKFRYILPVYGICRE-PVG-LVMEYMETGSLEKLLASEPLPWDLRFRIIHETA 126
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAK--QLEST 471
G+ ++H P+ +H D+K ANILL + DFGLAK L +
Sbjct: 127 VGMNFLHCMAPPL-------------LHLDLKPANILLDAHYHVKISDFGLAKCNGLSHS 173
Query: 472 RVTSM--MMGTSAYMPPEAIK---GTLTKKTDVYSFGIVLLELLTGLKPIVVDSN 521
SM + GT AY+PPE I+ K DVYSF IV+ +LT KP + N
Sbjct: 174 HDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKN 228
>AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase MLK1
protein.
Length = 1066
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/171 (31%), Positives = 89/171 (52%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E K + L+H NI+ + G + P C+V ++ GG L ++ K + + + A
Sbjct: 139 EAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIA 198
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H+ + PI IH D+KS+NIL+ + + + DFGLA
Sbjct: 199 RGMNYLHDEA--------IVPI----IHRDLKSSNILILQKVENGDLSNKILKITDFGLA 246
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE I+ ++ +K +DV+S+G++L ELLTG P
Sbjct: 247 REWHRTTKMSAA-GTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVP 296
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + L H NI+ + ++ P C+V +Y GG L +A + + + + A
Sbjct: 164 EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H + P+ IH D+KS NILL + + + DFGLA
Sbjct: 224 RGMHYLHCEA--------LVPV----IHRDLKSNNILLLQPIESDDMEHKTLKITDFGLA 271
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE IK T +K +DV+SFG++L ELLTG P
Sbjct: 272 REWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + L H NI+ + ++ P C+V +Y GG L +A + + + + A
Sbjct: 164 EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H + P+ IH D+KS NILL + + + DFGLA
Sbjct: 224 RGMHYLHCEA--------LVPV----IHRDLKSNNILLLQPIESDDMEHKTLKITDFGLA 271
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE IK T +K +DV+SFG++L ELLTG P
Sbjct: 272 REWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + L H NI+ + ++ P C+V +Y GG L +A + + + + A
Sbjct: 164 EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H + P+ IH D+KS NILL + + + DFGLA
Sbjct: 224 RGMHYLHCEA--------LVPV----IHRDLKSNNILLLQHIESDDMEHKTLKITDFGLA 271
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE IK T +K +DV+SFG++L ELLTG P
Sbjct: 272 REWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + L H NI+ + ++ P C+V +Y GG L +A + + + + A
Sbjct: 164 EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H + P+ IH D+KS NILL + + + DFGLA
Sbjct: 224 RGMHYLHCEA--------LVPV----IHRDLKSNNILLLQPIESDDMEHKTLKITDFGLA 271
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE IK T +K +DV+SFG++L ELLTG P
Sbjct: 272 REWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 76.2 bits (179), Expect = 3e-13
Identities = 56/171 (32%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + L H NI+ + ++ P C+V +Y GG L +A + + + + A
Sbjct: 164 EARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIA 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKP--------MLCDFGLA 465
G+ Y+H + P+ IH D+KS NILL + + + DFGLA
Sbjct: 224 RGMHYLHCEA--------LVPV----IHRDLKSNNILLLQPIESDDMEHKTLKITDFGLA 271
Query: 466 KQLESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
++ T S GT A+M PE IK T +K +DV+SFG++L ELLTG P
Sbjct: 272 REWHKTTQMSAA-GTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVP 321
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/211 (27%), Positives = 99/211 (46%), Gaps = 11/211 (5%)
Query: 318 VFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGP 377
VF G H L V VKC + N L E+K L +L+H+NIV ++ +
Sbjct: 30 VFKGRHREKHDLEVA-VKCINKKNLAKSQT--LLGKEIKILKELKHENIVALYDFQEMAN 86
Query: 378 TPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
+ +V +Y +GG L + + A + L+E+ + A ++ +H+ K I ++ D+ P
Sbjct: 87 SVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHS--KGI-IHRDLKPQN 143
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGT-LTK 495
+ + AN + + DFG A+ L+S + + + G+ YM PE I
Sbjct: 144 ILLSNPAGRRAN---PNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDG 200
Query: 496 KTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
K D++S G ++ + LTG P S +L +
Sbjct: 201 KADLWSIGTIVYQCLTGKAPFQASSPQDLRL 231
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/211 (27%), Positives = 99/211 (46%), Gaps = 11/211 (5%)
Query: 318 VFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGP 377
VF G H L V VKC + N L E+K L +L+H+NIV ++ +
Sbjct: 46 VFKGRHREKHDLEVA-VKCINKKNLAKSQT--LLGKEIKILKELKHENIVALYDFQEMAN 102
Query: 378 TPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
+ +V +Y +GG L + + A + L+E+ + A ++ +H+ K I ++ D+ P
Sbjct: 103 SVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHS--KGI-IHRDLKPQN 159
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGT-LTK 495
+ + AN + + DFG A+ L+S + + + G+ YM PE I
Sbjct: 160 ILLSNPAGRRAN---PNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDG 216
Query: 496 KTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
K D++S G ++ + LTG P S +L +
Sbjct: 217 KADLWSIGTIVYQCLTGKAPFQASSPQDLRL 247
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 99 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 154
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 155 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 206
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 207 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 264
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 265 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 304
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 99 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 154
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 155 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 206
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 207 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 264
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 265 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 304
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 99 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 154
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 155 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 206
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 207 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 264
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 265 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 304
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 99 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 154
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 155 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 206
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 207 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 264
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 265 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 304
>AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 312
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 99 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 154
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 155 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 206
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 207 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 264
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 265 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 304
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 74.5 bits (175), Expect = 1e-12
Identities = 66/229 (28%), Positives = 109/229 (47%), Gaps = 25/229 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E+ L+ L+H NI+ + + +D T I +Y +GG+L +KI L + +L
Sbjct: 131 EIVILALLQHDNIIAYYNHFMDNTTLLIELEYCNGGNLYDKI----LRQKDKLFEEEMVV 186
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLEST-R 472
L + + V I G +H D+K+ NI LTK L D+GLAK+L S
Sbjct: 187 WYLFQIVSAVSCIHKAG--------ILHRDIKTLNIFLTKANLIKLGDYGLAKKLNSEYS 238
Query: 473 VTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
+ ++GT YM PE +G K+D+++ G V+ ELLT LK D+ LN+ +
Sbjct: 239 MAETLVGTPYYMSPELCQGVKYNFKSDIWAVGCVIFELLT-LKR-TFDATNPLNLCVKIV 296
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
Q + M V+ + + ++ CL + + RP+ DE+ +
Sbjct: 297 QGIRA---------MEVDSSQYSLELIQMVHSCLDQDPEQRPTADELLD 336
>X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 74.1 bits (174), Expect = 1e-12
Identities = 81/276 (29%), Positives = 128/276 (46%), Gaps = 36/276 (13%)
Query: 317 EVFVGTHNRYG-QLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSID 375
+VF H R+ + A+K C DV + E + +++ ++IV I+G
Sbjct: 35 QVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLI--EEAAKMKKIKFQHIVSIYGVCKQ 92
Query: 376 GPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPI 435
P IV +++ GSL + ++ L R II T+ + ++H+ +KP P+
Sbjct: 93 -PLG-IVMEFMANGSLEKVLSTHSLCWKLRFRIIHETSLAMNFLHS-IKP--------PL 141
Query: 436 TTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE-STRV----TSMMMGTSAYMPPEAI- 489
+H D+K NILL + + DFGL+K +E STR+ S + G +Y+PPE
Sbjct: 142 ----LHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFL 197
Query: 490 --KGTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMV 547
K DVYSF IV+ ELLT KP N+ + +V + L V
Sbjct: 198 ESNKAPGPKYDVYSFAIVIWELLTQKKPY-----SGFNMMMIIIRVA---AGMRPSLQPV 249
Query: 548 VERW-TRAQGIYELAKRCLSDNRDNRPS-IDEVCET 581
++W + AQ + +L KRC + RP +D ET
Sbjct: 250 SDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET 285
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 74.1 bits (174), Expect = 1e-12
Identities = 81/276 (29%), Positives = 128/276 (46%), Gaps = 36/276 (13%)
Query: 317 EVFVGTHNRYG-QLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSID 375
+VF H R+ + A+K C DV + E + +++ ++IV I+G
Sbjct: 35 QVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLI--EEAAKMKKIKFQHIVSIYGVCKQ 92
Query: 376 GPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPI 435
P IV +++ GSL + ++ L R II T+ + ++H+ +KP P+
Sbjct: 93 -PLG-IVMEFMANGSLEKVLSTHSLCWKLRFRIIHETSLAMNFLHS-IKP--------PL 141
Query: 436 TTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE-STRV----TSMMMGTSAYMPPEAI- 489
+H D+K NILL + + DFGL+K +E STR+ S + G +Y+PPE
Sbjct: 142 ----LHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFL 197
Query: 490 --KGTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMV 547
K DVYSF IV+ ELLT KP N+ + +V + L V
Sbjct: 198 ESNKAPGPKYDVYSFAIVIWELLTQKKPY-----SGFNMMMIIIRVA---AGMRPSLQPV 249
Query: 548 VERW-TRAQGIYELAKRCLSDNRDNRPS-IDEVCET 581
++W + AQ + +L KRC + RP +D ET
Sbjct: 250 SDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET 285
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 74.1 bits (174), Expect = 1e-12
Identities = 81/276 (29%), Positives = 128/276 (46%), Gaps = 36/276 (13%)
Query: 317 EVFVGTHNRYG-QLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSID 375
+VF H R+ + A+K C DV + E + +++ ++IV I+G
Sbjct: 35 QVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLI--EEAAKMKKIKFQHIVSIYGVCKQ 92
Query: 376 GPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPI 435
P IV +++ GSL + ++ L R II T+ + ++H+ +KP P+
Sbjct: 93 -PLG-IVMEFMANGSLEKVLSTHSLCWKLRFRIIHETSLAMNFLHS-IKP--------PL 141
Query: 436 TTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE-STRV----TSMMMGTSAYMPPEAI- 489
+H D+K NILL + + DFGL+K +E STR+ S + G +Y+PPE
Sbjct: 142 ----LHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFL 197
Query: 490 --KGTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMV 547
K DVYSF IV+ ELLT KP N+ + +V + L V
Sbjct: 198 ESNKAPGPKYDVYSFAIVIWELLTQKKPY-----SGFNMMMIIIRVA---AGMRPSLQPV 249
Query: 548 VERW-TRAQGIYELAKRCLSDNRDNRPS-IDEVCET 581
++W + AQ + +L KRC + RP +D ET
Sbjct: 250 SDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIET 285
>AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein.
Length = 426
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 90/201 (44%), Gaps = 21/201 (10%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV+ G N ++ K+ + D I E+ LSQ I FG +
Sbjct: 33 EVYKGIDNHTKEVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSPYITRYFGSYLKS 88
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + L E I+ +GL Y+H+ K
Sbjct: 89 TKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERK------------ 136
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLT 494
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE IK
Sbjct: 137 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYD 193
Query: 495 KKTDVYSFGIVLLELLTGLKP 515
K D++S GI +EL G P
Sbjct: 194 FKADIWSLGITAIELAKGEPP 214
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/173 (29%), Positives = 86/173 (49%), Gaps = 18/173 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
LFN EV + +H N+V ++ + G ++ +++ GG+L + ++ LNE Q +
Sbjct: 449 LFN-EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVC 507
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL- 468
+ L Y+H G IH D+KS +ILLT D + L DFG Q+
Sbjct: 508 EAVLQALAYLH-------AQG--------VIHRDIKSDSILLTLDGRVKLSDFGFCAQIS 552
Query: 469 ESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDS 520
+ ++GT +M PE I +L + D++S GI+++E++ G P DS
Sbjct: 553 KDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDS 605
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 72.9 bits (171), Expect = 3e-12
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 17/137 (12%)
Query: 381 IVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYI 440
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K I
Sbjct: 14 IIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK---------------I 58
Query: 441 HGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLTKKTD 498
H D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK K D
Sbjct: 59 HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKAD 118
Query: 499 VYSFGIVLLELLTGLKP 515
++S GI +EL G P
Sbjct: 119 IWSLGITAIELARGEPP 135
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 72.9 bits (171), Expect = 3e-12
Identities = 46/137 (33%), Positives = 72/137 (52%), Gaps = 17/137 (12%)
Query: 381 IVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYI 440
I+ +Y+ GGS ++ + L+E Q I+ +GL Y+H+ K I
Sbjct: 14 IIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKK---------------I 58
Query: 441 HGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK-GTLTKKTD 498
H D+K+AN+LL++ + L DFG+A QL T++ + +GT +M PE IK K D
Sbjct: 59 HRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKAD 118
Query: 499 VYSFGIVLLELLTGLKP 515
++S GI +EL G P
Sbjct: 119 IWSLGITAIELARGEPP 135
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/173 (29%), Positives = 86/173 (49%), Gaps = 18/173 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
LFN EV + +H N+V ++ + G ++ +++ GG+L + ++ LNE Q +
Sbjct: 449 LFN-EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVC 507
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL- 468
+ L Y+H G IH D+KS +ILLT D + L DFG Q+
Sbjct: 508 EAVLQALAYLH-------AQG--------VIHRDIKSDSILLTLDGRVKLSDFGFCAQIS 552
Query: 469 ESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDS 520
+ ++GT +M PE I +L + D++S GI+++E++ G P DS
Sbjct: 553 KDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDS 605
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 72.9 bits (171), Expect = 3e-12
Identities = 51/173 (29%), Positives = 86/173 (49%), Gaps = 18/173 (10%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
LFN EV + +H N+V ++ + G ++ +++ GG+L + ++ LNE Q +
Sbjct: 449 LFN-EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVC 507
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL- 468
+ L Y+H G IH D+KS +ILLT D + L DFG Q+
Sbjct: 508 EAVLQALAYLH-------AQG--------VIHRDIKSDSILLTLDGRVKLSDFGFCAQIS 552
Query: 469 ESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDS 520
+ ++GT +M PE I +L + D++S GI+++E++ G P DS
Sbjct: 553 KDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDS 605
>X63128-1|CAA44839.1| 513|Homo sapiens activin receptor protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>X62381-1|CAA44245.1| 513|Homo sapiens activin receptor protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>M93415-1|AAA35504.1| 513|Homo sapiens activin type II receptor
protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>BC069707-1|AAH69707.1| 513|Homo sapiens activin A receptor, type
IIA, precursor protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>BC067418-1|AAH67418.1| 513|Homo sapiens activin A receptor, type
IIA, precursor protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>BC067417-1|AAH67417.1| 513|Homo sapiens activin A receptor, type
IIA protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 72.5 bits (170), Expect = 4e-12
Identities = 74/267 (27%), Positives = 130/267 (48%), Gaps = 41/267 (15%)
Query: 323 HNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIV 382
+N + ++AVK +K Q + D F AE + QL+H+ +V ++ P I+
Sbjct: 271 YNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQEPI-YII 322
Query: 383 CKYIDGGSLME--KIAAKV-LNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFY 439
+Y++ GSL++ K + + L N+ L++ + AEG+ ++ E N Y
Sbjct: 323 TEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE------ERN---------Y 367
Query: 440 IHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTLTKK 496
IH D+++ANIL++ + DFGLA+ +E T+ + PEAI GT T K
Sbjct: 368 IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK 427
Query: 497 TDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQG 556
+DV+SFGI+L E++T + + G N E + N + +V +
Sbjct: 428 SDVWSFGILLTEIVTHGR---IPYPGMTN----PEVIQNLERGY-----RMVRPDNCPEE 475
Query: 557 IYELAKRCLSDNRDNRPSIDEVCETLE 583
+Y+L + C + ++RP+ D + LE
Sbjct: 476 LYQLMRLCWKERPEDRPTFDYLRSVLE 502
>AC009480-2|AAX93050.1| 513|Homo sapiens unknown protein.
Length = 513
Score = 72.5 bits (170), Expect = 4e-12
Identities = 52/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA + E
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFE 348
Query: 470 ---STRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AK091708-1|BAC03728.1| 471|Homo sapiens protein ( Homo sapiens
cDNA FLJ34389 fis, clone HCHON2000087. ).
Length = 471
Score = 72.1 bits (169), Expect = 5e-12
Identities = 55/175 (31%), Positives = 92/175 (52%), Gaps = 26/175 (14%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGP-TP---CIVCKYIDGGSLMEKI-AAKVLNENQR 405
FN E+K++ + NI+ IFG ID TP IV +Y + G+L E + K L +R
Sbjct: 247 FNKEIKTMKKFESPNILRIFGICIDETVTPPQFSIVMEYCELGTLRELLDREKDLTLGKR 306
Query: 406 LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLA 465
+ ++ G A GL +H++ P +HG ++S+N L+T+ + L F L
Sbjct: 307 MVLVLGAARGLYRLHHSEAP-------------ELHGKIRSSNFLVTQGYQVKLAGFELR 353
Query: 466 K-----QLESTRVTSMMMGTSAYMPPEAIKGTLTK---KTDVYSFGIVLLELLTG 512
K L +TR + + ++AY+ P+ ++ + K+++YSFGIVL E+ TG
Sbjct: 354 KTQTSMSLGTTREKTDRVKSTAYLSPQELEDVFYQYDVKSEIYSFGIVLWEIATG 408
>AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kinase
splice variant d protein.
Length = 491
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kinase
1c protein.
Length = 518
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kinase
1b protein.
Length = 606
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kinase
1a protein.
Length = 579
Score = 72.1 bits (169), Expect = 5e-12
Identities = 53/169 (31%), Positives = 93/169 (55%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ ++K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKP 228
>BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 71.7 bits (168), Expect = 7e-12
Identities = 53/169 (31%), Positives = 92/169 (54%), Gaps = 14/169 (8%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI 408
+ F E++ LS++ H NIV ++G ++ P C+V +Y +GGSL VL+ + L
Sbjct: 72 KAFIVELRQLSRVNHPNIVKLYGACLN-PV-CLVMEYAEGGSLYN-----VLHGAEPLPY 124
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM-LCDFGLAKQ 467
+ A + + + + + P IH D+K N+LL + +CDFG A
Sbjct: 125 YTA-AHAMSWCLQCSQGVAYLHSMQPKAL--IHRDLKPPNLLLVAGGTVLKICDFGTACD 181
Query: 468 LESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKP 515
++ T +T+ G++A+M PE +G+ +K DV+S+GI+L E++T KP
Sbjct: 182 IQ-THMTNNK-GSAAWMAPEVFEGSNYNEKCDVFSWGIILWEVITRRKP 228
>BC125184-1|AAI25185.1| 625|Homo sapiens interleukin-1
receptor-associated kinase 2 protein.
Length = 625
Score = 71.7 bits (168), Expect = 7e-12
Identities = 56/191 (29%), Positives = 100/191 (52%), Gaps = 27/191 (14%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI----AAKVLNENQ 404
R F AE++ + H N++P+ G+ + Y+ GSL +++ + L Q
Sbjct: 252 RFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQ 311
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCD--- 461
R+ I SG ++Y+H +E+ IH +VKS+N+LL ++ P L
Sbjct: 312 RVSICSGLLCAVEYLHG----LEI-----------IHSNVKSSNVLLDQNLTPKLAHPMA 356
Query: 462 --FGLAKQLESTRVTSMMMGTS-AYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ K+ + T + + ++ TS AY+P + I+ G LTK+ D++S GIVL E+LTG+ P +
Sbjct: 357 HLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGI-PAM 415
Query: 518 VDSNGNLNIKD 528
++ + +KD
Sbjct: 416 DNNRSPVYLKD 426
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>AJ496794-1|CAD43180.3| 625|Homo sapiens interleukin-1 receptor
associated kinase-2 protein.
Length = 625
Score = 71.7 bits (168), Expect = 7e-12
Identities = 56/191 (29%), Positives = 100/191 (52%), Gaps = 27/191 (14%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI----AAKVLNENQ 404
R F AE++ + H N++P+ G+ + Y+ GSL +++ + L Q
Sbjct: 252 RFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQ 311
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCD--- 461
R+ I SG ++Y+H +E+ IH +VKS+N+LL ++ P L
Sbjct: 312 RVSICSGLLCAVEYLHG----LEI-----------IHSNVKSSNVLLDQNLTPKLAHPMA 356
Query: 462 --FGLAKQLESTRVTSMMMGTS-AYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ K+ + T + + ++ TS AY+P + I+ G LTK+ D++S GIVL E+LTG+ P +
Sbjct: 357 HLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGI-PAM 415
Query: 518 VDSNGNLNIKD 528
++ + +KD
Sbjct: 416 DNNRSPVYLKD 426
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>AF026273-1|AAB87669.1| 590|Homo sapiens interleukin-1
receptor-associated kinase-2 protein.
Length = 590
Score = 71.7 bits (168), Expect = 7e-12
Identities = 56/191 (29%), Positives = 100/191 (52%), Gaps = 27/191 (14%)
Query: 349 RLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI----AAKVLNENQ 404
R F AE++ + H N++P+ G+ + Y+ GSL +++ + L Q
Sbjct: 252 RFFQAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQGGSDPLPWPQ 311
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCD--- 461
R+ I SG ++Y+H +E+ IH +VKS+N+LL ++ P L
Sbjct: 312 RVSICSGLLCAVEYLHG----LEI-----------IHSNVKSSNVLLDQNLTPKLAHPMA 356
Query: 462 --FGLAKQLESTRVTSMMMGTS-AYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ K+ + T + + ++ TS AY+P + I+ G LTK+ D++S GIVL E+LTG+ P +
Sbjct: 357 HLCPVNKRSKYTMMKTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGI-PAM 415
Query: 518 VDSNGNLNIKD 528
++ + +KD
Sbjct: 416 DNNRSPVYLKD 426
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 71.7 bits (168), Expect = 7e-12
Identities = 64/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 336
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 337 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 379
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 71.3 bits (167), Expect = 9e-12
Identities = 63/229 (27%), Positives = 102/229 (44%), Gaps = 32/229 (13%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + + +
Sbjct: 180 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRI 239
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 240 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 284
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVE 531
T+ + GT Y+PPE I+G + +K D++S G++ E L G P ++ Y E
Sbjct: 285 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANT--------YQE 335
Query: 532 QVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
++ D V E G +L R L N RP + EV E
Sbjct: 336 TYKRISRVEFTFPDFVTE------GARDLISRLLKHNPSQRPMLREVLE 378
>AK027291-1|BAB55019.1| 322|Homo sapiens protein ( Homo sapiens
cDNA FLJ14385 fis, clone HEMBA1002212, weakly similar to
TYROSINE-PROTEIN KINASE 2 (EC 2.7.1.112). ).
Length = 322
Score = 71.3 bits (167), Expect = 9e-12
Identities = 75/275 (27%), Positives = 125/275 (45%), Gaps = 38/275 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEASDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD++S+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIESSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLTGLKPIVVDSNGN------LNIKDYVEQVMNENKDITQLLDMVV 548
K D+++FG+ L E++T P + SN N + D+ ++ ++M
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDNDDEDKTFDESDFDDEAYYAALGTRPPINM-E 284
Query: 549 ERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
E Q + EL C +++ +RPS + E LE
Sbjct: 285 ELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>AF237709-1|AAF71521.1| 322|Homo sapiens spermatogenesis-related
protein kinase protein.
Length = 322
Score = 71.3 bits (167), Expect = 9e-12
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 36/274 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEASDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD+KS+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLT-GLKPIVVDSNGNLNIKDYVEQVMNENKDITQL---LDMVVER 550
K D+++FG+ L E++T + I + ++ + K + E ++ L + +E
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEE 285
Query: 551 WTRA-QGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ Q + EL C +++ +RPS + E LE
Sbjct: 286 LDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>AF189722-1|AAF69107.1| 322|Homo sapiens PDZ-binding kinase
protein.
Length = 322
Score = 71.3 bits (167), Expect = 9e-12
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 36/274 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEASDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD+KS+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLT-GLKPIVVDSNGNLNIKDYVEQVMNENKDITQL---LDMVVER 550
K D+++FG+ L E++T + I + ++ + K + E ++ L + +E
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEE 285
Query: 551 WTRA-QGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ Q + EL C +++ +RPS + E LE
Sbjct: 286 LDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 70.9 bits (166), Expect = 1e-11
Identities = 66/237 (27%), Positives = 116/237 (48%), Gaps = 34/237 (14%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME--KIAAKV-LNENQRLEII 409
AE + QL+H+ +V ++ P I+ +Y++ GSL++ K + + L N+ L++
Sbjct: 288 AEANLMKQLQHQRLVRLYAVVTQEPI-YIITEYMENGSLVDFLKTPSGIKLTINKLLDMA 346
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ AEG+ ++ E N YIH D+++ANIL++ + DFGLA+ +E
Sbjct: 347 AQIAEGMAFIE------ERN---------YIHRDLRAANILVSDTLSCKIADFGLARLIE 391
Query: 470 STRVTSM--MMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
T+ + PEAI GT T K+DV+SFGI+L E++T + + G N
Sbjct: 392 DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN- 447
Query: 527 KDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
E + N + +V + +Y+L + C + ++RP+ D + LE
Sbjct: 448 ---PEVIQNLERGY-----RMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 496
>D31770-1|BAA06548.1| 513|Homo sapiens activin typeII A receptor
precursor protein.
Length = 513
Score = 70.9 bits (166), Expect = 1e-11
Identities = 51/169 (30%), Positives = 85/169 (50%), Gaps = 18/169 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCI----VCKYIDGGSLMEKIAAKVLNENQRLEII 409
EV SL ++H+NI+ G G + + + + + GSL + + A V++ N+ I
Sbjct: 234 EVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL- 468
A GL Y+H + ++ +G I+ H D+KS N+LL + + DFGLA +
Sbjct: 294 ETMARGLAYLHEDIPGLK-DGHKPAIS----HRDIKSKNVLLKNNLTACIADFGLALKFV 348
Query: 469 --ESTRVTSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLEL 509
+S T +GT YM PE ++G + + D+Y+ G+VL EL
Sbjct: 349 AGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWEL 397
>BC015191-1|AAH15191.1| 322|Homo sapiens PDZ binding kinase
protein.
Length = 322
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 36/274 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEANDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD+KS+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLT-GLKPIVVDSNGNLNIKDYVEQVMNENKDITQL---LDMVVER 550
K D+++FG+ L E++T + I + ++ + K + E ++ L + +E
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEE 285
Query: 551 WTRA-QGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ Q + EL C +++ +RPS + E LE
Sbjct: 286 LDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>AB027250-1|BAA99577.1| 322|Homo sapiens MPAKK-like protein kinase
cap site form 2 protein.
Length = 322
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 36/274 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEANDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD+KS+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLT-GLKPIVVDSNGNLNIKDYVEQVMNENKDITQL---LDMVVER 550
K D+++FG+ L E++T + I + ++ + K + E ++ L + +E
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEE 285
Query: 551 WTRA-QGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ Q + EL C +++ +RPS + E LE
Sbjct: 286 LDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>AB027249-1|BAA99576.1| 322|Homo sapiens MAPKK like protein kinase
protein.
Length = 322
Score = 70.9 bits (166), Expect = 1e-11
Identities = 74/274 (27%), Positives = 127/274 (46%), Gaps = 36/274 (13%)
Query: 330 AVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPI--FGYSIDGPTPCIVCKYID 387
AVKK+ +Y+ RL + E K L L H NIV F + DG C+ +Y
Sbjct: 62 AVKKINPICNDHYRSVYQKRLMD-EAKILKSLHHPNIVGYRAFTEANDGSL-CLAMEYGG 119
Query: 388 GGSLMEKIAAKVLNENQR------LEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIH 441
SL + I + L++ A GLKY+H K +H
Sbjct: 120 EKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKK--------------LLH 165
Query: 442 GDVKSANILLTKDCKPM-LCDFGLAKQL-ESTRVT---SMMMGTSAYMPPEAIK--GTLT 494
GD+KS+N+++ D + + +CD G++ L E+ VT + +GT + P EA++ G +T
Sbjct: 166 GDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVIT 225
Query: 495 KKTDVYSFGIVLLELLT-GLKPIVVDSNGNLNIKDYVEQVMNENKDITQL---LDMVVER 550
K D+++FG+ L E++T + I + ++ + K + E ++ L + +E
Sbjct: 226 DKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEE 285
Query: 551 WTRA-QGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+ Q + EL C +++ +RPS + E LE
Sbjct: 286 LDESYQKVIELFSVCTNEDPKDRPSAAHIVEALE 319
>X77533-1|CAA54671.1| 512|Homo sapiens activin type II receptor
protein.
Length = 512
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLEK 584
T+E+
Sbjct: 456 TIEE 459
>BC099642-1|AAH99642.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLEK 584
T+E+
Sbjct: 456 TIEE 459
>BC096245-1|AAH96245.1| 303|Homo sapiens ACVR2B protein protein.
Length = 303
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 23 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 82
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 83 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 138
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 139 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 196
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 197 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 246
Query: 581 TLEK 584
T+E+
Sbjct: 247 TIEE 250
>BC096244-1|AAH96244.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLEK 584
T+E+
Sbjct: 456 TIEE 459
>BC096243-1|AAH96243.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLEK 584
T+E+
Sbjct: 456 TIEE 459
>AB209449-1|BAD92686.1| 514|Homo sapiens activin A type IIB
receptor precursor variant protein.
Length = 514
Score = 70.1 bits (164), Expect = 2e-11
Identities = 59/244 (24%), Positives = 109/244 (44%), Gaps = 29/244 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 234 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 293
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 294 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 349
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 350 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 407
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 408 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 457
Query: 581 TLEK 584
T+E+
Sbjct: 458 TIEE 461
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 87/179 (48%), Gaps = 32/179 (17%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME---KIAAK------VLNENQ 404
E++++SQ H NIV + + +V K + GGS+++ I AK VL+E+
Sbjct: 63 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGL 464
I+ EGL+Y+H NG IH DVK+ NILL +D + DFG+
Sbjct: 123 IATILREVLEGLEYLHK-------NGQ--------IHRDVKAGNILLGEDGSVQIADFGV 167
Query: 465 AKQLES------TRVTSMMMGTSAYMPPEAIKGT--LTKKTDVYSFGIVLLELLTGLKP 515
+ L + +V +GT +M PE ++ K D++SFGI +EL TG P
Sbjct: 168 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAP 226
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK---VLNENQRLEIIS 410
EV L+ ++H NIV + + IV Y +GG L ++I A+ + E+Q L+
Sbjct: 51 EVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFV 110
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
LK+VH+ +H D+KS NI LTKD L DFG+A+ L S
Sbjct: 111 QICLALKHVHDRK---------------ILHRDIKSQNIFLTKDGTVQLGDFGIARVLNS 155
Query: 471 T-RVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
T + +GT Y+ PE + K+D+++ G VL EL T S NL +K
Sbjct: 156 TVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLK 214
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK---VLNENQRLEIIS 410
EV L+ ++H NIV + + IV Y +GG L ++I A+ + E+Q L+
Sbjct: 51 EVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFV 110
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
LK+VH+ +H D+KS NI LTKD L DFG+A+ L S
Sbjct: 111 QICLALKHVHDRK---------------ILHRDIKSQNIFLTKDGTVQLGDFGIARVLNS 155
Query: 471 T-RVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
T + +GT Y+ PE + K+D+++ G VL EL T S NL +K
Sbjct: 156 TVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLK 214
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 87/179 (48%), Gaps = 32/179 (17%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME---KIAAK------VLNENQ 404
E++++SQ H NIV + + +V K + GGS+++ I AK VL+E+
Sbjct: 63 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGL 464
I+ EGL+Y+H NG IH DVK+ NILL +D + DFG+
Sbjct: 123 IATILREVLEGLEYLHK-------NGQ--------IHRDVKAGNILLGEDGSVQIADFGV 167
Query: 465 AKQLES------TRVTSMMMGTSAYMPPEAIKGT--LTKKTDVYSFGIVLLELLTGLKP 515
+ L + +V +GT +M PE ++ K D++SFGI +EL TG P
Sbjct: 168 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAP 226
>AF060202-1|AAC64515.1| 512|Homo sapiens activin receptor type IIB
protein.
Length = 512
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 29/243 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLE 583
T+E
Sbjct: 456 TIE 458
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 84/179 (46%), Gaps = 20/179 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK---VLNENQRLEIIS 410
EV L+ ++H NIV + + IV Y +GG L ++I A+ + E+Q L+
Sbjct: 58 EVAVLANMKHPNIVQYRESFEENGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFV 117
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLES 470
LK+VH+ +H D+KS NI LTKD L DFG+A+ L S
Sbjct: 118 QICLALKHVHDRK---------------ILHRDIKSQNIFLTKDGTVQLGDFGIARVLNS 162
Query: 471 T-RVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
T + +GT Y+ PE + K+D+++ G VL EL T S NL +K
Sbjct: 163 TVELARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLK 221
>AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein.
Length = 467
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 87/179 (48%), Gaps = 32/179 (17%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME---KIAAK------VLNENQ 404
E++++SQ H NIV + + +V K + GGS+++ I AK VL+E+
Sbjct: 3 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 62
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGL 464
I+ EGL+Y+H NG IH DVK+ NILL +D + DFG+
Sbjct: 63 IATILREVLEGLEYLHK-------NGQ--------IHRDVKAGNILLGEDGSVQIADFGV 107
Query: 465 AKQLES------TRVTSMMMGTSAYMPPEAIKGT--LTKKTDVYSFGIVLLELLTGLKP 515
+ L + +V +GT +M PE ++ K D++SFGI +EL TG P
Sbjct: 108 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAP 166
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/179 (31%), Positives = 87/179 (48%), Gaps = 32/179 (17%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLME---KIAAK------VLNENQ 404
E++++SQ H NIV + + +V K + GGS+++ I AK VL+E+
Sbjct: 63 EIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEST 122
Query: 405 RLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGL 464
I+ EGL+Y+H NG IH DVK+ NILL +D + DFG+
Sbjct: 123 IATILREVLEGLEYLHK-------NGQ--------IHRDVKAGNILLGEDGSVQIADFGV 167
Query: 465 AKQLES------TRVTSMMMGTSAYMPPEAIKGT--LTKKTDVYSFGIVLLELLTGLKP 515
+ L + +V +GT +M PE ++ K D++SFGI +EL TG P
Sbjct: 168 SAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAP 226
>AB008681-1|BAA24180.2| 512|Homo sapiens activin receptor type IIB
protein.
Length = 512
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 29/243 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTP----CIVCKYIDGGSLMEKIAAKVLNENQRLEII 409
E+ S ++H+N++ G ++ + D GSL + + ++ N+ +
Sbjct: 232 EIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVA 291
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ GL Y+H V G I H D KS N+LL D +L DFGLA + E
Sbjct: 292 ETMSRGLSYLHEDVPWCRGEGHKPSIA----HRDFKSKNVLLKSDLTAVLADFGLAVRFE 347
Query: 470 STRV---TSMMMGTSAYMPPEAIKGTLT------KKTDVYSFGIVLLELLTGLKPIVVDS 520
+ T +GT YM PE ++G + + D+Y+ G+VL EL++ K D
Sbjct: 348 PGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCK--AADG 405
Query: 521 NGNLNIKDYVEQVMNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCE 580
+ + + E++ ++ + +L ++VV + R + D+ P + ++C
Sbjct: 406 PVDEYMLPFEEEI-GQHPSLEELQEVVVHKKMRP---------TIKDHWLKHPGLAQLCV 455
Query: 581 TLE 583
T+E
Sbjct: 456 TIE 458
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 98 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 150
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 151 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 199
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 200 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 254
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 255 GRFTIKSDVWSFGILLTELTT 275
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 283 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 335
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 336 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 384
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 385 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 439
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 440 GRFTIKSDVWSFGILLTELTT 460
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 283 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 335
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 336 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 384
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 385 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 439
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 440 GRFTIKSDVWSFGILLTELTT 460
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 283 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 335
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 336 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 384
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 385 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 439
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 440 GRFTIKSDVWSFGILLTELTT 460
>AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 289 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 341
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 342 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 390
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 391 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 445
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 446 GRFTIKSDVWSFGILLTELTT 466
>AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 69.3 bits (162), Expect = 4e-11
Identities = 58/201 (28%), Positives = 100/201 (49%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +LRH+ +V ++ +
Sbjct: 283 EVWMGTWNGTTRVAIKTLK-------PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE 335
Query: 377 PTPCIVCKYIDGGSLMEKI---AAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y+ GSL++ + K L Q +++ + A G+ YV +N
Sbjct: 336 PI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVER------MN---- 384
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
Y+H D+++ANIL+ ++ + DFGLA+ +E T+ P A+
Sbjct: 385 -----YVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 439
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL T
Sbjct: 440 GRFTIKSDVWSFGILLTELTT 460
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 69.3 bits (162), Expect = 4e-11
Identities = 44/137 (32%), Positives = 71/137 (51%), Gaps = 17/137 (12%)
Query: 381 IVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYI 440
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K I
Sbjct: 20 IIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK---------------I 64
Query: 441 HGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAI-KGTLTKKTD 498
H D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I + K D
Sbjct: 65 HRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKAD 124
Query: 499 VYSFGIVLLELLTGLKP 515
++S GI +EL G P
Sbjct: 125 IWSLGITAIELAKGEPP 141
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
E++ + L+H NI+ ++ Y D ++ +Y G L +++ ++ L+E + II
Sbjct: 57 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 116
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A+ L Y H+ K + IH D+K N+LL + + DFG + S R
Sbjct: 117 ADALTYCHD--KKV-------------IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR 161
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
M GT Y+PPE I+G T +K D++ G++ ELL G P
Sbjct: 162 -RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 204
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 68.9 bits (161), Expect = 5e-11
Identities = 78/290 (26%), Positives = 140/290 (48%), Gaps = 45/290 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 258 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 310
Query: 377 PTPCIVCKYIDGGSLME-KIAAKVL------NENQRLEII-SG-------TAEGLKYVHN 421
P I+ +Y++ +L++ ++ K L N Q+L ++ +G T G+K N
Sbjct: 311 PI-YIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTIN 369
Query: 422 TVKPIEVNGDVSPITTF-----YIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM 476
K +++ ++ F YIH D+++ANIL++ + DFGLA+ +E T+
Sbjct: 370 --KLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAR 427
Query: 477 --MMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQV 533
+ PEAI GT T K+DV+SFGI+L E++T + + G N E +
Sbjct: 428 EGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVI 480
Query: 534 MNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
N + +V + +Y+L + C + ++RP+ D + LE
Sbjct: 481 QNLERGY-----RMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 525
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
E++ + L+H NI+ ++ Y D ++ +Y G L +++ ++ L+E + II
Sbjct: 88 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 147
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A+ L Y H+ K + IH D+K N+LL + + DFG + S R
Sbjct: 148 ADALTYCHD--KKV-------------IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR 192
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
M GT Y+PPE I+G T +K D++ G++ ELL G P
Sbjct: 193 -RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 235
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
E++ + L+H NI+ ++ Y D ++ +Y G L +++ ++ L+E + II
Sbjct: 72 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 131
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A+ L Y H+ K + IH D+K N+LL + + DFG + S R
Sbjct: 132 ADALTYCHD--KKV-------------IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR 176
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
M GT Y+PPE I+G T +K D++ G++ ELL G P
Sbjct: 177 -RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 219
>AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 526
Score = 68.9 bits (161), Expect = 5e-11
Identities = 78/290 (26%), Positives = 140/290 (48%), Gaps = 45/290 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N + ++AVK +K Q + D F AE + QL+H+ +V ++
Sbjct: 245 EVWMGYYNGHTKVAVKSLK---QGSMSPDA----FLAEANLMKQLQHQRLVRLYAVVTQE 297
Query: 377 PTPCIVCKYIDGGSLME-KIAAKVL------NENQRLEII-SG-------TAEGLKYVHN 421
P I+ +Y++ +L++ ++ K L N Q+L ++ +G T G+K N
Sbjct: 298 PI-YIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTIN 356
Query: 422 TVKPIEVNGDVSPITTF-----YIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM 476
K +++ ++ F YIH D+++ANIL++ + DFGLA+ +E T+
Sbjct: 357 --KLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAR 414
Query: 477 --MMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQV 533
+ PEAI GT T K+DV+SFGI+L E++T + + G N E +
Sbjct: 415 EGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGR---IPYPGMTN----PEVI 467
Query: 534 MNENKDITQLLDMVVERWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
N + +V + +Y+L + C + ++RP+ D + LE
Sbjct: 468 QNLERGY-----RMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 512
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
EV+ S LRH NI+ ++GY D ++ +Y G++ ++ +E + I+
Sbjct: 181 EVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITEL 240
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A L Y H+ K + IH D+K N+LL + + DFG + S+R
Sbjct: 241 ANALSYCHS--KRV-------------IHRDIKPENLLLGSAGELKIADFGWSVHAPSSR 285
Query: 473 VTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLKP 515
T+ + GT Y+PPE I+G + +K D++S G++ E L G P
Sbjct: 286 RTT-LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPP 328
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 68.9 bits (161), Expect = 5e-11
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
E++ + L+H NI+ ++ Y D ++ +Y G L +++ ++ L+E + II
Sbjct: 91 EIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 150
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A+ L Y H+ K + IH D+K N+LL + + DFG + S R
Sbjct: 151 ADALTYCHD--KKV-------------IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR 195
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
M GT Y+PPE I+G T +K D++ G++ ELL G P
Sbjct: 196 -RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 238
>Y10256-1|CAA71306.1| 947|Homo sapiens NIK, serine/threonine
protein-kinase protein.
Length = 947
Score = 68.5 bits (160), Expect = 6e-11
Identities = 57/192 (29%), Positives = 93/192 (48%), Gaps = 25/192 (13%)
Query: 346 VAIRLFNAE-VKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK-VLNEN 403
V + +F AE + + + L IVP++G +GP I + ++GGSL + + + L E+
Sbjct: 431 VRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPED 490
Query: 404 QRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKD-CKPMLCDF 462
+ L + EGL+Y+H + +HGDVK+ N+LL+ D LCDF
Sbjct: 491 RALYYLGQALEGLEYLH---------------SRRILHGDVKADNVLLSSDGSHAALCDF 535
Query: 463 GLAKQLESTRVTSMMM------GTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
G A L+ + ++ GT +M PE + G + K DV+S ++L +L G P
Sbjct: 536 GHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHP 595
Query: 516 IVVDSNGNLNIK 527
G L +K
Sbjct: 596 WTQFFRGPLCLK 607
>DQ314874-1|ABC40733.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 68.5 bits (160), Expect = 6e-11
Identities = 57/192 (29%), Positives = 93/192 (48%), Gaps = 25/192 (13%)
Query: 346 VAIRLFNAE-VKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK-VLNEN 403
V + +F AE + + + L IVP++G +GP I + ++GGSL + + + L E+
Sbjct: 431 VRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPED 490
Query: 404 QRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKD-CKPMLCDF 462
+ L + EGL+Y+H + +HGDVK+ N+LL+ D LCDF
Sbjct: 491 RALYYLGQALEGLEYLH---------------SRRILHGDVKADNVLLSSDGSHAALCDF 535
Query: 463 GLAKQLESTRVTSMMM------GTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
G A L+ + ++ GT +M PE + G + K DV+S ++L +L G P
Sbjct: 536 GHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHP 595
Query: 516 IVVDSNGNLNIK 527
G L +K
Sbjct: 596 WTQFFRGPLCLK 607
>BC035576-1|AAH35576.1| 947|Homo sapiens mitogen-activated protein
kinase kinase kinase 14 protein.
Length = 947
Score = 68.5 bits (160), Expect = 6e-11
Identities = 57/192 (29%), Positives = 93/192 (48%), Gaps = 25/192 (13%)
Query: 346 VAIRLFNAE-VKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK-VLNEN 403
V + +F AE + + + L IVP++G +GP I + ++GGSL + + + L E+
Sbjct: 431 VRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPED 490
Query: 404 QRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKD-CKPMLCDF 462
+ L + EGL+Y+H + +HGDVK+ N+LL+ D LCDF
Sbjct: 491 RALYYLGQALEGLEYLH---------------SRRILHGDVKADNVLLSSDGSHAALCDF 535
Query: 463 GLAKQLESTRVTSMMM------GTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
G A L+ + ++ GT +M PE + G + K DV+S ++L +L G P
Sbjct: 536 GHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHP 595
Query: 516 IVVDSNGNLNIK 527
G L +K
Sbjct: 596 WTQFFRGPLCLK 607
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 354 EVKSLSQLRHKNIVPIF-GYSIDGPTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEII 409
E L++++H NIV + +G IV +Y DGG LM+KI K+ E+ L
Sbjct: 50 EAVLLAKMKHPNIVAFKESFEAEGHL-YIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ G+ ++H K + +H D+KS NI LT++ K L DFG A+ L
Sbjct: 109 TQMCLGVNHIHK--KRV-------------LHRDIKSKNIFLTQNGKVKLGDFGSARLLS 153
Query: 470 STRV-TSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
+ +GT Y+PPE + K+D++S G +L EL T P +S NL +K
Sbjct: 154 NPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILK 213
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 354 EVKSLSQLRHKNIVPIF-GYSIDGPTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEII 409
E L++++H NIV + +G IV +Y DGG LM+KI K+ E+ L
Sbjct: 50 EAVLLAKMKHPNIVAFKESFEAEGHL-YIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ G+ ++H K + +H D+KS NI LT++ K L DFG A+ L
Sbjct: 109 TQMCLGVNHIHK--KRV-------------LHRDIKSKNIFLTQNGKVKLGDFGSARLLS 153
Query: 470 STRV-TSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
+ +GT Y+PPE + K+D++S G +L EL T P +S NL +K
Sbjct: 154 NPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILK 213
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 354 EVKSLSQLRHKNIVPIF-GYSIDGPTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEII 409
E L++++H NIV + +G IV +Y DGG LM+KI K+ E+ L
Sbjct: 71 EAVLLAKMKHPNIVAFKESFEAEGHL-YIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 129
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ G+ ++H K + +H D+KS NI LT++ K L DFG A+ L
Sbjct: 130 TQMCLGVNHIHK--KRV-------------LHRDIKSKNIFLTQNGKVKLGDFGSARLLS 174
Query: 470 STRV-TSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
+ +GT Y+PPE + K+D++S G +L EL T P +S NL +K
Sbjct: 175 NPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILK 234
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 68.1 bits (159), Expect = 8e-11
Identities = 57/180 (31%), Positives = 87/180 (48%), Gaps = 22/180 (12%)
Query: 354 EVKSLSQLRHKNIVPIF-GYSIDGPTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEII 409
E L++++H NIV + +G IV +Y DGG LM+KI K+ E+ L
Sbjct: 50 EAVLLAKMKHPNIVAFKESFEAEGHL-YIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWF 108
Query: 410 SGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLE 469
+ G+ ++H K + +H D+KS NI LT++ K L DFG A+ L
Sbjct: 109 TQMCLGVNHIHK--KRV-------------LHRDIKSKNIFLTQNGKVKLGDFGSARLLS 153
Query: 470 STRV-TSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
+ +GT Y+PPE + K+D++S G +L EL T P +S NL +K
Sbjct: 154 NPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILK 213
>M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor
protein.
Length = 937
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI-I 409
F E +++L H NIV + G C++ +YI+ G L E + + + +
Sbjct: 520 FQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDE 579
Query: 410 SGTAE-GLKYVHNTVKPIEVNGDVSPITT-FYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
GT + L + I++ + +++ F++H D+ + NIL+ + + D GL+++
Sbjct: 580 DGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSRE 639
Query: 468 LEST---RVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLT-GLKPIVVDSN 521
+ S RV S + +MPPEAI G + +D++SFG+VL E+ + GL+P SN
Sbjct: 640 IYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSN 698
>BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein.
Length = 940
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI-I 409
F E +++L H NIV + G C++ +YI+ G L E + + + +
Sbjct: 523 FQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDE 582
Query: 410 SGTAE-GLKYVHNTVKPIEVNGDVSPITT-FYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
GT + L + I++ + +++ F++H D+ + NIL+ + + D GL+++
Sbjct: 583 DGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSRE 642
Query: 468 LEST---RVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLT-GLKPIVVDSN 521
+ S RV S + +MPPEAI G + +D++SFG+VL E+ + GL+P SN
Sbjct: 643 IYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSN 701
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/179 (25%), Positives = 88/179 (49%), Gaps = 8/179 (4%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK-VLNENQRLEI 408
L E+K L +L+H+NIV ++ + +V +Y +GG L + + AK L+E+
Sbjct: 52 LLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVF 111
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL 468
+ A ++ +H+ K I ++ D+ P + + + +++ + + DFG A+ L
Sbjct: 112 LHQIAAAMRILHS--KGI-IHRDLKPQNILLSYANRRKSSV---SGIRIKIADFGFARYL 165
Query: 469 ESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
S + + + G+ YM PE I K D++S G V+ + L G P +S +L +
Sbjct: 166 HSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRM 224
>AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI-I 409
F E +++L H NIV + G C++ +YI+ G L E + + + +
Sbjct: 520 FQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDE 579
Query: 410 SGTAE-GLKYVHNTVKPIEVNGDVSPITT-FYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
GT + L + I++ + +++ F++H D+ + NIL+ + + D GL+++
Sbjct: 580 DGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSRE 639
Query: 468 LEST---RVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLT-GLKPIVVDSN 521
+ S RV S + +MPPEAI G + +D++SFG+VL E+ + GL+P SN
Sbjct: 640 IYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSN 698
>AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI-I 409
F E +++L H NIV + G C++ +YI+ G L E + + + +
Sbjct: 520 FQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDE 579
Query: 410 SGTAE-GLKYVHNTVKPIEVNGDVSPITT-FYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
GT + L + I++ + +++ F++H D+ + NIL+ + + D GL+++
Sbjct: 580 DGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSRE 639
Query: 468 LEST---RVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLT-GLKPIVVDSN 521
+ S RV S + +MPPEAI G + +D++SFG+VL E+ + GL+P SN
Sbjct: 640 IYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSN 698
>AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine
kinase-like orphan receptor 1 protein.
Length = 937
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 8/179 (4%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEI-I 409
F E +++L H NIV + G C++ +YI+ G L E + + + +
Sbjct: 520 FQQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDE 579
Query: 410 SGTAE-GLKYVHNTVKPIEVNGDVSPITT-FYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
GT + L + I++ + +++ F++H D+ + NIL+ + + D GL+++
Sbjct: 580 DGTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSRE 639
Query: 468 LEST---RVTSMMMGTSAYMPPEAIK-GTLTKKTDVYSFGIVLLELLT-GLKPIVVDSN 521
+ S RV S + +MPPEAI G + +D++SFG+VL E+ + GL+P SN
Sbjct: 640 IYSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSN 698
>AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protein
kinase MST4a protein.
Length = 354
Score = 67.7 bits (158), Expect = 1e-10
Identities = 51/175 (29%), Positives = 82/175 (46%), Gaps = 20/175 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EVF G NR Q+ K+ + D I E+ LSQ + +G + G
Sbjct: 37 EVFKGIDNRTQQVVAIKI---IDLEEAED-EIEDIQQEITVLSQCDSSYVTKYYGSYLKG 92
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
I+ +Y+ GGS ++ + A +E Q ++ +GL Y+H+ K
Sbjct: 93 SKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYLHSEKK------------ 140
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV-TSMMMGTSAYMPPEAIK 490
IH D+K+AN+LL++ L DFG+A QL T++ + +GT +M PE I+
Sbjct: 141 ---IHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQ 192
>AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein.
Length = 1100
Score = 67.7 bits (158), Expect = 1e-10
Identities = 46/179 (25%), Positives = 88/179 (49%), Gaps = 8/179 (4%)
Query: 350 LFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK-VLNENQRLEI 408
L E+K L +L+H+NIV ++ + +V +Y +GG L + + AK L+E+
Sbjct: 116 LLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVF 175
Query: 409 ISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL 468
+ A ++ +H+ K I ++ D+ P + + + +++ + + DFG A+ L
Sbjct: 176 LHQIAAAMRILHS--KGI-IHRDLKPQNILLSYANRRKSSV---SGIRIKIADFGFARYL 229
Query: 469 ESTRVTSMMMGTSAYMPPEAIKGT-LTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNI 526
S + + + G+ YM PE I K D++S G V+ + L G P +S +L +
Sbjct: 230 HSNMMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRM 288
>AL133380-4|CAI23046.1| 1036|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 1036
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/181 (32%), Positives = 86/181 (47%), Gaps = 27/181 (14%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + LRH NI+ + G + P C+V ++ GG+L +AA + R A
Sbjct: 171 EARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAANAAPDPR-------A 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFY----------IHGDVKSANILLTKD------CKP 457
G + + VN V +H D+KS+NILL + C
Sbjct: 224 PGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNK 283
Query: 458 ML--CDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLK 514
L DFGLA++ T S GT A+M PE IK +L +K +D++S+G++L ELLTG
Sbjct: 284 TLKITDFGLAREWHRTTKMSTA-GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEV 342
Query: 515 P 515
P
Sbjct: 343 P 343
>AL133380-3|CAI23045.1| 570|Homo sapiens mixed lineage kinase 4
(KIAA1804) protein.
Length = 570
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/181 (32%), Positives = 86/181 (47%), Gaps = 27/181 (14%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + LRH NI+ + G + P C+V ++ GG+L +AA + R A
Sbjct: 171 EARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAANAAPDPR-------A 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFY----------IHGDVKSANILLTKD------CKP 457
G + + VN V +H D+KS+NILL + C
Sbjct: 224 PGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEKIEHDDICNK 283
Query: 458 ML--CDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLK 514
L DFGLA++ T S GT A+M PE IK +L +K +D++S+G++L ELLTG
Sbjct: 284 TLKITDFGLAREWHRTTKMSTA-GTYAWMAPEVIKSSLFSKGSDIWSYGVLLWELLTGEV 342
Query: 515 P 515
P
Sbjct: 343 P 343
>BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 66.9 bits (156), Expect = 2e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLN--ENQRLEIISG 411
E+ ++QL H N++ ++ +V +Y+DGG L ++I + N E + +
Sbjct: 151 EISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQ 210
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL-LTKDCKPM-LCDFGLAKQLE 469
EG++++H + +H D+K NIL + +D K + + DFGLA++ +
Sbjct: 211 ICEGIRHMHQM---------------YILHLDLKPENILCVNRDAKQIKIIDFGLARRYK 255
Query: 470 STRVTSMMMGTSAYMPPEAIKGTLTK-KTDVYSFGIVLLELLTGLKPIVVDSN 521
+ GT ++ PE + TD++S G++ LL+GL P + D++
Sbjct: 256 PREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDND 308
>BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 66.9 bits (156), Expect = 2e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLN--ENQRLEIISG 411
E+ ++QL H N++ ++ +V +Y+DGG L ++I + N E + +
Sbjct: 151 EISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQ 210
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL-LTKDCKPM-LCDFGLAKQLE 469
EG++++H + +H D+K NIL + +D K + + DFGLA++ +
Sbjct: 211 ICEGIRHMHQM---------------YILHLDLKPENILCVNRDAKQIKIIDFGLARRYK 255
Query: 470 STRVTSMMMGTSAYMPPEAIKGTLTK-KTDVYSFGIVLLELLTGLKPIVVDSN 521
+ GT ++ PE + TD++S G++ LL+GL P + D++
Sbjct: 256 PREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDND 308
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 66.9 bits (156), Expect = 2e-10
Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK---VLNENQRLEIIS 410
EV L +++H NIV F + IV +Y DGG LM++I + + +E+Q L
Sbjct: 51 EVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFV 110
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKD-CKPMLCDFGLAKQL- 468
+ GLK++H+ +H D+K+ NI L+K+ L DFG+A+ L
Sbjct: 111 QISLGLKHIHDRK---------------ILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN 155
Query: 469 ESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLT 511
S + +GT Y+ PE + KTD++S G VL EL T
Sbjct: 156 NSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCT 199
>AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-420G6 on chromosome 6. ).
Length = 388
Score = 66.9 bits (156), Expect = 2e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLN--ENQRLEIISG 411
E+ ++QL H N++ ++ +V +Y+DGG L ++I + N E + +
Sbjct: 151 EISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQ 210
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL-LTKDCKPM-LCDFGLAKQLE 469
EG++++H + +H D+K NIL + +D K + + DFGLA++ +
Sbjct: 211 ICEGIRHMHQM---------------YILHLDLKPENILCVNRDAKQIKIIDFGLARRYK 255
Query: 470 STRVTSMMMGTSAYMPPEAIKGTLTK-KTDVYSFGIVLLELLTGLKPIVVDSN 521
+ GT ++ PE + TD++S G++ LL+GL P + D++
Sbjct: 256 PREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDND 308
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 66.9 bits (156), Expect = 2e-10
Identities = 53/164 (32%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK---VLNENQRLEIIS 410
EV L +++H NIV F + IV +Y DGG LM++I + + +E+Q L
Sbjct: 51 EVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFV 110
Query: 411 GTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKD-CKPMLCDFGLAKQL- 468
+ GLK++H+ +H D+K+ NI L+K+ L DFG+A+ L
Sbjct: 111 QISLGLKHIHDRK---------------ILHRDIKAQNIFLSKNGMVAKLGDFGIARVLN 155
Query: 469 ESTRVTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLT 511
S + +GT Y+ PE + KTD++S G VL EL T
Sbjct: 156 NSMELARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYELCT 199
>AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-145H9 on chromosome 6. ).
Length = 388
Score = 66.9 bits (156), Expect = 2e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 20/173 (11%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLN--ENQRLEIISG 411
E+ ++QL H N++ ++ +V +Y+DGG L ++I + N E + +
Sbjct: 151 EISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQ 210
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANIL-LTKDCKPM-LCDFGLAKQLE 469
EG++++H + +H D+K NIL + +D K + + DFGLA++ +
Sbjct: 211 ICEGIRHMHQM---------------YILHLDLKPENILCVNRDAKQIKIIDFGLARRYK 255
Query: 470 STRVTSMMMGTSAYMPPEAIKGTLTK-KTDVYSFGIVLLELLTGLKPIVVDSN 521
+ GT ++ PE + TD++S G++ LL+GL P + D++
Sbjct: 256 PREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDND 308
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 66.9 bits (156), Expect = 2e-10
Identities = 48/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISGT 412
E++ + L+H NI+ ++ + D ++ +Y G L +++ ++ L+E + II
Sbjct: 91 EIEIQAHLQHPNILRLYNHFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEL 150
Query: 413 AEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTR 472
A+ L Y H+ K + IH D+K N+LL + + DFG + S R
Sbjct: 151 ADALTYCHD--KKV-------------IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLR 195
Query: 473 VTSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKP 515
M GT Y+PPE I+G T +K D++ G++ ELL G P
Sbjct: 196 -RKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPP 238
>X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein.
Length = 348
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 97 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 149
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 150 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 198
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 199 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 256
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 257 TIKSDVWSFGILLMEIVT 274
>M16592-1|AAA52644.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 254 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 306
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 307 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 355
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 356 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 413
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 414 TIKSDVWSFGILLMEIVT 431
>M16591-1|AAA52643.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 254 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 306
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 307 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 355
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 356 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 413
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 414 TIKSDVWSFGILLMEIVT 431
>BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 275 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 327
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 328 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 376
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 377 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 434
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 435 TIKSDVWSFGILLMEIVT 452
>BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 275 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 327
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 328 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 376
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 377 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 434
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 435 TIKSDVWSFGILLMEIVT 452
>BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 275 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 327
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 328 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 376
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 377 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 434
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 435 TIKSDVWSFGILLMEIVT 452
>BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 275 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 327
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 328 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 376
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 377 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 434
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 435 TIKSDVWSFGILLMEIVT 452
>BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 275 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 327
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 328 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 376
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 377 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 434
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 435 TIKSDVWSFGILLMEIVT 452
>AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 254 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 306
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 307 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 355
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 356 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 413
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 414 TIKSDVWSFGILLMEIVT 431
>AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 253 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 305
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 306 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 354
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 355 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 412
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 413 TIKSDVWSFGILLMEIVT 430
>AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 253 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 305
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 306 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 354
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 355 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 412
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 413 TIKSDVWSFGILLMEIVT 430
>AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 254 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 306
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 307 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 355
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 356 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 413
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 414 TIKSDVWSFGILLMEIVT 431
>AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22779 fis, clone KAIA1741. ).
Length = 505
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/198 (27%), Positives = 102/198 (51%), Gaps = 23/198 (11%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++ T+N++ ++AVK +K +++ F AE + L+H +V +
Sbjct: 254 EVWMATYNKHTKVAVKTMK-------PGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKE 306
Query: 377 PTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPIT 436
P I+ +++ GSL++ + + ++ ++I +A+ + + IE
Sbjct: 307 PI-YIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQ----IAEGMAFIEQRN------ 355
Query: 437 TFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK-GTL 493
YIH D+++ANIL++ + DFGLA+ +E T+ + PEAI G+
Sbjct: 356 --YIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSF 413
Query: 494 TKKTDVYSFGIVLLELLT 511
T K+DV+SFGI+L+E++T
Sbjct: 414 TIKSDVWSFGILLMEIVT 431
>AJ311798-1|CAC84640.1| 1036|Homo sapiens mixed lineage kinase 4beta
protein.
Length = 1036
Score = 66.5 bits (155), Expect = 3e-10
Identities = 58/181 (32%), Positives = 86/181 (47%), Gaps = 27/181 (14%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + LRH NI+ + G + P C+V ++ GG+L +AA + R A
Sbjct: 171 EARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAANAAPDPR-------A 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFY----------IHGDVKSANILLTKD------CKP 457
G + + VN V +H D+KS+NILL ++ C
Sbjct: 224 PGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNK 283
Query: 458 ML--CDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLK 514
L DFGLA++ T S GT A+M PE IK +L +K +D++S G++L ELLTG
Sbjct: 284 TLKITDFGLAREWHRTTKMSTA-GTYAWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEV 342
Query: 515 P 515
P
Sbjct: 343 P 343
>AJ311797-1|CAC84639.1| 570|Homo sapiens mixed lineage kinase
4alpha protein.
Length = 570
Score = 66.5 bits (155), Expect = 3e-10
Identities = 58/181 (32%), Positives = 86/181 (47%), Gaps = 27/181 (14%)
Query: 354 EVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAKVLNENQRLEIISGTA 413
E + + LRH NI+ + G + P C+V ++ GG+L +AA + R A
Sbjct: 171 EARLFAMLRHPNIIELRGVCLQQPHLCLVLEFARGGALNRALAAANAAPDPR-------A 223
Query: 414 EGLKYVHNTVKPIEVNGDVSPITTFY----------IHGDVKSANILLTKD------CKP 457
G + + VN V +H D+KS+NILL ++ C
Sbjct: 224 PGPRRARRIPPHVLVNWAVQIARGMLYLHEEAFVPILHRDLKSSNILLLEEIEHDDICNK 283
Query: 458 ML--CDFGLAKQLESTRVTSMMMGTSAYMPPEAIKGTL-TKKTDVYSFGIVLLELLTGLK 514
L DFGLA++ T S GT A+M PE IK +L +K +D++S G++L ELLTG
Sbjct: 284 TLKITDFGLAREWHRTTKMSTA-GTYAWMAPEVIKSSLFSKGSDIWSCGVLLWELLTGEV 342
Query: 515 P 515
P
Sbjct: 343 P 343
>Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein.
Length = 459
Score = 66.1 bits (154), Expect = 3e-10
Identities = 55/175 (31%), Positives = 85/175 (48%), Gaps = 22/175 (12%)
Query: 359 SQLRHKNIVPIF-GYSIDGPTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAE 414
++++H NIV + +G IV +Y DGG LM+KI K+ E+ L +
Sbjct: 8 AKMKHPNIVAFKESFEAEGHL-YIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCL 66
Query: 415 GLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRV- 473
G+ ++H K + +H D+KS NI LT++ K L DFG A+ L +
Sbjct: 67 GVNHIHK--KRV-------------LHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAF 111
Query: 474 TSMMMGTSAYMPPEAIKG-TLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIK 527
+GT Y+PPE + K+D++S G +L EL T P +S NL +K
Sbjct: 112 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILK 166
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 66.1 bits (154), Expect = 3e-10
Identities = 48/179 (26%), Positives = 81/179 (45%), Gaps = 17/179 (9%)
Query: 339 QFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK 398
Q N + L E+ + + ++ NIV + G +V +Y+ GGSL + +
Sbjct: 300 QMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET 359
Query: 399 VLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM 458
++E Q + + L+++H+ IH D+KS NILL D
Sbjct: 360 CMDEGQIAAVCRECLQALEFLHSNQ---------------VIHRDIKSDNILLGMDGSVK 404
Query: 459 LCDFGLAKQLESTR-VTSMMMGTSAYMPPEAI-KGTLTKKTDVYSFGIVLLELLTGLKP 515
L DFG Q+ + S M+GT +M PE + + K D++S GI+ +E++ G P
Sbjct: 405 LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPP 463
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 66.1 bits (154), Expect = 3e-10
Identities = 48/179 (26%), Positives = 81/179 (45%), Gaps = 17/179 (9%)
Query: 339 QFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK 398
Q N + L E+ + + ++ NIV + G +V +Y+ GGSL + +
Sbjct: 300 QMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET 359
Query: 399 VLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM 458
++E Q + + L+++H+ IH D+KS NILL D
Sbjct: 360 CMDEGQIAAVCRECLQALEFLHSNQ---------------VIHRDIKSDNILLGMDGSVK 404
Query: 459 LCDFGLAKQLESTR-VTSMMMGTSAYMPPEAI-KGTLTKKTDVYSFGIVLLELLTGLKP 515
L DFG Q+ + S M+GT +M PE + + K D++S GI+ +E++ G P
Sbjct: 405 LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPP 463
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 66.1 bits (154), Expect = 3e-10
Identities = 48/179 (26%), Positives = 81/179 (45%), Gaps = 17/179 (9%)
Query: 339 QFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKIAAK 398
Q N + L E+ + + ++ NIV + G +V +Y+ GGSL + +
Sbjct: 300 QMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET 359
Query: 399 VLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPM 458
++E Q + + L+++H+ IH D+KS NILL D
Sbjct: 360 CMDEGQIAAVCRECLQALEFLHSNQ---------------VIHRDIKSDNILLGMDGSVK 404
Query: 459 LCDFGLAKQLESTR-VTSMMMGTSAYMPPEAI-KGTLTKKTDVYSFGIVLLELLTGLKP 515
L DFG Q+ + S M+GT +M PE + + K D++S GI+ +E++ G P
Sbjct: 405 LTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPP 463
>Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewing's
sarcoma cell line) mRNA encoding open reading frame.
).
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>D14497-1|BAA03387.1| 467|Homo sapiens proto-oncogene protein
protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>CR542284-1|CAG47079.1| 467|Homo sapiens MAP3K8 protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>BC113566-1|AAI13567.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>BC104833-1|AAI04834.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>AY309013-1|AAP45053.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>AL161651-12|CAI14227.1| 467|Homo sapiens mitogen-activated protein
kinase kinase kinase 8 protein.
Length = 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 51/169 (30%), Positives = 86/169 (50%), Gaps = 21/169 (12%)
Query: 353 AEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI-AAKVLNENQRLEIISG 411
++V+ + RH+NI ++G + G T + + +GGS++EK+ + + E + + +
Sbjct: 177 SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKH 236
Query: 412 TAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQL-ES 470
+GL ++H+ K + IH D+K +NI+ K +L DFGL+ Q+ E
Sbjct: 237 VLKGLDFLHS--KKV-------------IHHDIKPSNIVF-MSTKAVLVDFGLSVQMTED 280
Query: 471 TRVTSMMMGTSAYMPPEAI--KGTLTKKTDVYSFGIVLLELLTGLKPIV 517
+ GT YM PE I +G T K D+YS G L+ + TG P V
Sbjct: 281 VYFPKDLRGTEIYMSPEVILCRGHST-KADIYSLGATLIHMQTGTPPWV 328
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 65.3 bits (152), Expect = 6e-10
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +L+H +V ++ +
Sbjct: 281 EVWLGTWNGNTKVAIKTLK-------PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 333
Query: 377 PTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y++ GSL++ + + L +++ + A G+ Y+ +N
Sbjct: 334 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER------MN---- 382
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
YIH D++SANIL+ + DFGLA+ +E T+ P A+
Sbjct: 383 -----YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPERALY 437
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL+T
Sbjct: 438 GRFTIKSDVWSFGILLTELVT 458
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 65.3 bits (152), Expect = 6e-10
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +L+H +V ++ +
Sbjct: 284 EVWMGTWNGNTKVAIKTLK-------PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
Query: 377 PTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y++ GSL++ + + L +++ + A G+ Y+ +N
Sbjct: 337 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER------MN---- 385
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
YIH D++SANIL+ + DFGLA+ +E T+ P A+
Sbjct: 386 -----YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPERALY 440
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL+T
Sbjct: 441 GRFTIKSDVWSFGILLTELVT 461
>AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens
cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to
Rattus norvegicus tyrosine protein kinase pp60-c-src
mRNA. ).
Length = 251
Score = 65.3 bits (152), Expect = 6e-10
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 22/167 (13%)
Query: 351 FNAEVKSLSQLRHKNIVPIFGYSIDGPTPCIVCKYIDGGSLMEKI---AAKVLNENQRLE 407
F E + + +LRH+ +V ++ + P IV +Y+ GSL++ + K L Q ++
Sbjct: 25 FLQEAQVMKKLRHEKLVQLYAVVSEEPI-YIVTEYMSKGSLLDFLKGETGKYLRLPQLVD 83
Query: 408 IISGTAEGLKYVHNTVKPIEVNGDVSPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQ 467
+ + A G+ YV +N Y+H D+++ANIL+ ++ + DFGLA+
Sbjct: 84 MAAQIASGMAYVER------MN---------YVHRDLRAANILVGENLVCKVADFGLARL 128
Query: 468 LESTRVTSMM---MGTSAYMPPEAIKGTLTKKTDVYSFGIVLLELLT 511
+E T+ P A+ G T K+DV+SFGI+L EL T
Sbjct: 129 IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTT 175
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 64.9 bits (151), Expect = 8e-10
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +L+H +V ++ +
Sbjct: 232 EVWLGTWNGNTKVAIKTLK-------PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 284
Query: 377 PTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y++ GSL++ + + L +++ + A G+ Y+ +N
Sbjct: 285 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER------MN---- 333
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
YIH D++SANIL+ + DFGLA+ +E T+ P A+
Sbjct: 334 -----YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 388
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL+T
Sbjct: 389 GRFTIKSDVWSFGILLTELVT 409
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 64.9 bits (151), Expect = 8e-10
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +L+H +V ++ +
Sbjct: 281 EVWLGTWNGNTKVAIKTLK-------PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 333
Query: 377 PTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y++ GSL++ + + L +++ + A G+ Y+ +N
Sbjct: 334 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER------MN---- 382
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
YIH D++SANIL+ + DFGLA+ +E T+ P A+
Sbjct: 383 -----YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 437
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL+T
Sbjct: 438 GRFTIKSDVWSFGILLTELVT 458
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 64.9 bits (151), Expect = 8e-10
Identities = 56/201 (27%), Positives = 98/201 (48%), Gaps = 29/201 (14%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++GT N ++A+K +K ++ F E + + +L+H +V ++ +
Sbjct: 284 EVWMGTWNGNTKVAIKTLK-------PGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEE 336
Query: 377 PTPCIVCKYIDGGSLMEKIA---AKVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDVS 433
P IV +Y++ GSL++ + + L +++ + A G+ Y+ +N
Sbjct: 337 PI-YIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIER------MN---- 385
Query: 434 PITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSMM---MGTSAYMPPEAIK 490
YIH D++SANIL+ + DFGLA+ +E T+ P A+
Sbjct: 386 -----YIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALY 440
Query: 491 GTLTKKTDVYSFGIVLLELLT 511
G T K+DV+SFGI+L EL+T
Sbjct: 441 GRFTIKSDVWSFGILLTELVT 461
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 64.9 bits (151), Expect = 8e-10
Identities = 67/274 (24%), Positives = 128/274 (46%), Gaps = 42/274 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N ++AVK +K ++++ F E + L+H +V ++
Sbjct: 239 EVWMGYYNNSTKVAVKTLK-------PGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTRE 291
Query: 377 PTPCIVCKYIDGGSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDV 432
I+ +Y+ GSL++ + + KVL + ++ + AEG+ Y+
Sbjct: 292 EPIYIITEYMAKGSLLDFLKSDEGGKVLLP-KLIDFSAQIAEGMAYIERKN--------- 341
Query: 433 SPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK 490
YIH D+++AN+L+++ + DFGLA+ +E T+ + PEAI
Sbjct: 342 ------YIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAIN 395
Query: 491 -GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVE 549
G T K+DV+SFGI+L E++T K + G N V +++ + ++ + E
Sbjct: 396 FGCFTIKSDVWSFGILLYEIVTYGK---IPYPGRTNAD--VMTALSQGYRMPRVENCPDE 450
Query: 550 RWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+Y++ K C + + RP+ D + L+
Sbjct: 451 -------LYDIMKMCWKEKAEERPTFDYLQSVLD 477
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 64.9 bits (151), Expect = 8e-10
Identities = 67/274 (24%), Positives = 128/274 (46%), Gaps = 42/274 (15%)
Query: 317 EVFVGTHNRYGQLAVKKVKCYLQFNYKHDVAIRLFNAEVKSLSQLRHKNIVPIFGYSIDG 376
EV++G +N ++AVK +K ++++ F E + L+H +V ++
Sbjct: 260 EVWMGYYNNSTKVAVKTLK-------PGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTRE 312
Query: 377 PTPCIVCKYIDGGSLMEKIAA----KVLNENQRLEIISGTAEGLKYVHNTVKPIEVNGDV 432
I+ +Y+ GSL++ + + KVL + ++ + AEG+ Y+
Sbjct: 313 EPIYIITEYMAKGSLLDFLKSDEGGKVLLP-KLIDFSAQIAEGMAYIERKN--------- 362
Query: 433 SPITTFYIHGDVKSANILLTKDCKPMLCDFGLAKQLESTRVTSM--MMGTSAYMPPEAIK 490
YIH D+++AN+L+++ + DFGLA+ +E T+ + PEAI
Sbjct: 363 ------YIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAIN 416
Query: 491 -GTLTKKTDVYSFGIVLLELLTGLKPIVVDSNGNLNIKDYVEQVMNENKDITQLLDMVVE 549
G T K+DV+SFGI+L E++T K + G N V +++ + ++ + E
Sbjct: 417 FGCFTIKSDVWSFGILLYEIVTYGK---IPYPGRTNAD--VMTALSQGYRMPRVENCPDE 471
Query: 550 RWTRAQGIYELAKRCLSDNRDNRPSIDEVCETLE 583
+Y++ K C + + RP+ D + L+
Sbjct: 472 -------LYDIMKMCWKEKAEERPTFDYLQSVLD 498
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.132 0.374
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,365,042
Number of Sequences: 224733
Number of extensions: 2721904
Number of successful extensions: 11246
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 818
Number of HSP's successfully gapped in prelim test: 1543
Number of HSP's that attempted gapping in prelim test: 7339
Number of HSP's gapped (non-prelim): 3524
length of query: 598
length of database: 73,234,838
effective HSP length: 94
effective length of query: 504
effective length of database: 52,109,936
effective search space: 26263407744
effective search space used: 26263407744
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 68 (31.5 bits)
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