Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002490-TA|BGIBMGA002490-PA|IPR001478|PDZ/DHR/GLGF
(78 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D572BB Cluster: PREDICTED: similar to CG31158-PB... 71 3e-12
UniRef50_UPI00015B5AAF Cluster: PREDICTED: similar to arf6 guani... 71 5e-12
UniRef50_Q6IJE9 Cluster: HDC15037; n=1; Drosophila melanogaster|... 60 1e-08
UniRef50_A7RPA4 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 36 0.12
UniRef50_UPI0000D5632D Cluster: PREDICTED: similar to CG30084-PF... 35 0.27
UniRef50_UPI0000F1FDA9 Cluster: PREDICTED: hypothetical protein;... 34 0.63
UniRef50_UPI000069E409 Cluster: Atrophin-1-interacting protein 1... 34 0.63
UniRef50_Q5VWL1 Cluster: Membrane-associated guanylate kinase, W... 33 0.84
UniRef50_UPI000065DCC0 Cluster: PDZ domain-containing protein 1 ... 33 1.1
UniRef50_Q7QE86 Cluster: ENSANGP00000017577; n=1; Anopheles gamb... 33 1.5
UniRef50_Q21074 Cluster: Putative uncharacterized protein magi-1... 33 1.5
UniRef50_Q7PV46 Cluster: ENSANGP00000015778; n=2; Culicidae|Rep:... 32 1.9
UniRef50_Q9HD26 Cluster: Golgi-associated PDZ and coiled-coil mo... 32 2.6
UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2; Salini... 31 3.4
UniRef50_Q21426 Cluster: Putative uncharacterized protein cnk-1;... 31 3.4
UniRef50_Q9NZN5 Cluster: Rho guanine nucleotide exchange factor ... 31 3.4
UniRef50_UPI0000E4724F Cluster: PREDICTED: similar to golgi asso... 31 4.5
UniRef50_UPI0000D5573E Cluster: PREDICTED: similar to Tyrosine-p... 31 4.5
UniRef50_UPI000065EBB9 Cluster: Homolog of Homo sapiens "Splice ... 31 4.5
UniRef50_Q4S7I1 Cluster: Chromosome 13 SCAF14715, whole genome s... 31 4.5
UniRef50_Q4RIG1 Cluster: Chromosome 11 SCAF15043, whole genome s... 31 5.9
UniRef50_Q6NIS8 Cluster: Putative uncharacterized protein; n=1; ... 31 5.9
UniRef50_Q29H53 Cluster: GA12994-PA; n=1; Drosophila pseudoobscu... 31 5.9
UniRef50_UPI0000F217A1 Cluster: PREDICTED: similar to membrane a... 30 7.8
UniRef50_Q1DJZ9 Cluster: Putative uncharacterized protein; n=1; ... 30 7.8
>UniRef50_UPI0000D572BB Cluster: PREDICTED: similar to CG31158-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG31158-PB, isoform B - Tribolium castaneum
Length = 953
Score = 71.3 bits (167), Expect = 3e-12
Identities = 35/60 (58%), Positives = 47/60 (78%), Gaps = 1/60 (1%)
Query: 1 MADERLVVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPAARSGEVSMHS-ILWISQTKI 59
M++E LVVLNRS+N GFGFSLLG+ GLP +IY I ++SPAA SGEV + IL +++T +
Sbjct: 1 MSEELLVVLNRSENSGFGFSLLGKPGLPPIIYNILDDSPAAESGEVEVGDVILKVNETDV 60
>UniRef50_UPI00015B5AAF Cluster: PREDICTED: similar to arf6
guanine nucleotide exchange factor; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to arf6 guanine
nucleotide exchange factor - Nasonia vitripennis
Length = 1130
Score = 70.9 bits (166), Expect = 5e-12
Identities = 33/52 (63%), Positives = 40/52 (76%)
Query: 1 MADERLVVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPAARSGEVSMHSIL 52
MA+E LV LNRSD+ GFG SLL AGLPHVIY++ ENSPAA SG+V ++
Sbjct: 1 MAEELLVTLNRSDSTGFGISLLRTAGLPHVIYDVVENSPAADSGKVEAGDVI 52
>UniRef50_Q6IJE9 Cluster: HDC15037; n=1; Drosophila
melanogaster|Rep: HDC15037 - Drosophila melanogaster
(Fruit fly)
Length = 148
Score = 59.7 bits (138), Expect = 1e-08
Identities = 31/48 (64%), Positives = 36/48 (75%), Gaps = 1/48 (2%)
Query: 1 MADERLVVLNRSD-NLGFGFSLLGEAGLPHVIYEIEENSPAARSGEVS 47
M++E VVL RS+ + GFGFSLLG G PHVIY+I ENSPAA G VS
Sbjct: 1 MSEELKVVLRRSEQHSGFGFSLLGTTGPPHVIYDIVENSPAADCGAVS 48
>UniRef50_A7RPA4 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 376
Score = 36.3 bits (80), Expect = 0.12
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 1 MADERLVVLNRSDNLGFGFSLLG--EAGLPHVIYEIEENSPAARSG 44
+ + R V++N+ G G S+ G E G+P +I EI + PAAR G
Sbjct: 269 IGEPRTVIVNKDKTEGLGISITGGKEHGVPILISEIHDGMPAARCG 314
>UniRef50_UPI0000D5632D Cluster: PREDICTED: similar to CG30084-PF,
isoform F; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG30084-PF, isoform F - Tribolium castaneum
Length = 650
Score = 35.1 bits (77), Expect = 0.27
Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 2/63 (3%)
Query: 1 MADERLVVLNRSDNLGFGFSLLG--EAGLPHVIYEIEENSPAARSGEVSMHSILWISQTK 58
MA V L++ D+ GF L G + G P VI ++ SPA R+G ++ S++ ++ T
Sbjct: 1 MASLITVRLSKGDSPSLGFRLQGGKDFGTPLVIQKVNGGSPAERAGLLAGDSVIKVNNTD 60
Query: 59 IIH 61
+ +
Sbjct: 61 VFN 63
>UniRef50_UPI0000F1FDA9 Cluster: PREDICTED: hypothetical protein;
n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 501
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 5 RLVVLNRSDNLGFGFSLLGEAG--LPHVIYEIEENSPAARSG 44
RL VL R + GFGF L +AG HV+ ++E S A R+G
Sbjct: 43 RLCVLRREEGQGFGFYLSRDAGRCRGHVVRQVEPWSSAERAG 84
>UniRef50_UPI000069E409 Cluster: Atrophin-1-interacting protein 1
(Atrophin-1-interacting protein A) (Membrane-associated
guanylate kinase inverted-2) (MAGI-2).; n=2; Xenopus
tropicalis|Rep: Atrophin-1-interacting protein 1
(Atrophin-1-interacting protein A) (Membrane-associated
guanylate kinase inverted-2) (MAGI-2). - Xenopus
tropicalis
Length = 1089
Score = 33.9 bits (74), Expect = 0.63
Identities = 24/65 (36%), Positives = 37/65 (56%), Gaps = 10/65 (15%)
Query: 7 VVLNRSDNLGFGFSLLG-----EAG----LPHVIYEIEENSPAARSGEVSM-HSILWISQ 56
VV++R +N GFGF ++ E+G +PH I I E SPA R G++ + IL ++
Sbjct: 852 VVIHRKENEGFGFVIISSLNRPESGATIAVPHKIGRIIEGSPADRCGKLKVGDRILAVNS 911
Query: 57 TKIIH 61
II+
Sbjct: 912 QSIIN 916
>UniRef50_Q5VWL1 Cluster: Membrane-associated guanylate kinase, WW
and PDZ domain-containing protein 3; n=43;
Euteleostomi|Rep: Membrane-associated guanylate kinase,
WW and PDZ domain-containing protein 3 - Homo sapiens
(Human)
Length = 1481
Score = 33.5 bits (73), Expect = 0.84
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 6/48 (12%)
Query: 7 VVLNRSDNLGFGFSLLGEAG------LPHVIYEIEENSPAARSGEVSM 48
VVL R +N GFGF +L +PH I + E SPA R G++ +
Sbjct: 852 VVLQRKENEGFGFVILTSKNKPPPGVIPHKIGRVIEGSPADRCGKLKV 899
>UniRef50_UPI000065DCC0 Cluster: PDZ domain-containing protein 1
(CFTR-associated protein of 70 kDa) (Na/Pi cotransporter
C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+)
exchanger regulatory factor 3) (Sodium-hydrogen
exchanger regulatory factor 3).; n=1; Takifugu
rubripes|Rep: PDZ domain-containing protein 1
(CFTR-associated protein of 70 kDa) (Na/Pi cotransporter
C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+)
exchanger regulatory factor 3) (Sodium-hydrogen
exchanger regulatory factor 3). - Takifugu rubripes
Length = 527
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 16 GFGFSLLGEAGLP-HVIYEIEENSPAARSGEVSMHSILWISQTKIIHYLRSRI 67
GFGFSL+ E H I +IE NSPA SG M ++ ++ ++ + ++
Sbjct: 240 GFGFSLIYEQNKGGHFIKDIEINSPAQSSGLKEMDRLVAVNSKEVDSWTHDQV 292
>UniRef50_Q7QE86 Cluster: ENSANGP00000017577; n=1; Anopheles
gambiae str. PEST|Rep: ENSANGP00000017577 - Anopheles
gambiae str. PEST
Length = 139
Score = 32.7 bits (71), Expect = 1.5
Identities = 23/54 (42%), Positives = 31/54 (57%), Gaps = 3/54 (5%)
Query: 1 MADERLVVLNRS-DNLGFGFSLLGEAGL-PHVIYEIEENSPAARSGEVSMHSIL 52
MA+E VL S D FGF LL + + HVIY+I EN+PA +V + I+
Sbjct: 1 MAEEVTAVLRMSKDGTTFGF-LLRQIDIGEHVIYKIIENTPADMCAKVEIGDIV 53
>UniRef50_Q21074 Cluster: Putative uncharacterized protein magi-1;
n=2; Fungi/Metazoa group|Rep: Putative uncharacterized
protein magi-1 - Caenorhabditis elegans
Length = 1092
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 1/43 (2%)
Query: 7 VVLNRSDNLGFGFSLLGEAGLP-HVIYEIEENSPAARSGEVSM 48
V+L+R++N GFGF L+ + +I+ SPAAR G +S+
Sbjct: 862 VLLHRNENDGFGFVLMSSQHKNGSTVGQIQPGSPAARCGRLSV 904
>UniRef50_Q7PV46 Cluster: ENSANGP00000015778; n=2; Culicidae|Rep:
ENSANGP00000015778 - Anopheles gambiae str. PEST
Length = 267
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 8 VLNRSDNLGFGFSLLGEAGLP-HVIYEIEENSPAARSGEVSMHSILWISQTKIIHYLRSR 66
V+ R+D G+GF+L E G P I ++++ SPA +G I+ ++ I +
Sbjct: 6 VVKRADFDGYGFNLHAEKGRPGQYIGKVDDGSPAESAGLRQGDRIIEVNGQNITTETHKK 65
Query: 67 IDMTFKYINNST 78
+ K + N T
Sbjct: 66 VVELIKTVPNET 77
>UniRef50_Q9HD26 Cluster: Golgi-associated PDZ and coiled-coil
motif-containing protein; n=29; Euteleostomi|Rep:
Golgi-associated PDZ and coiled-coil motif-containing
protein - Homo sapiens (Human)
Length = 462
Score = 31.9 bits (69), Expect = 2.6
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 2/42 (4%)
Query: 5 RLVVLNRSDNLGFGFSLLG--EAGLPHVIYEIEENSPAARSG 44
R V+L + D+ G G S+ G E G+P +I EI PA R G
Sbjct: 287 RKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCG 328
>UniRef50_A4X9C6 Cluster: Thioester reductase domain; n=2;
Salinispora|Rep: Thioester reductase domain - Salinispora
tropica CNB-440
Length = 2376
Score = 31.5 bits (68), Expect = 3.4
Identities = 13/37 (35%), Positives = 19/37 (51%)
Query: 24 EAGLPHVIYEIEENSPAARSGEVSMHSILWISQTKII 60
E GLP IY ++E S + G H +W+S I+
Sbjct: 1881 ERGLPVSIYRVDEISGDSEQGRCQTHDFVWLSMKGIL 1917
>UniRef50_Q21426 Cluster: Putative uncharacterized protein cnk-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein cnk-1 - Caenorhabditis elegans
Length = 801
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/37 (40%), Positives = 22/37 (59%)
Query: 4 ERLVVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPA 40
E ++ RSDN+ +G ++ HVI EI+E SPA
Sbjct: 261 ESALLRRRSDNINWGLNIQSSYRGVHVISEIKEGSPA 297
>UniRef50_Q9NZN5 Cluster: Rho guanine nucleotide exchange factor 12;
n=34; Deuterostomia|Rep: Rho guanine nucleotide exchange
factor 12 - Homo sapiens (Human)
Length = 1544
Score = 31.5 bits (68), Expect = 3.4
Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 3/58 (5%)
Query: 4 ERLVVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPAARSGEVSMHSILWISQTKIIH 61
+R V++ + DN GFG ++ G+ P + ++E+ A R+G + I+ ++ T + H
Sbjct: 70 QRCVIIQKDDN-GFGLTVSGDN--PVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTH 124
>UniRef50_UPI0000E4724F Cluster: PREDICTED: similar to golgi
associated PDZ domain and coiled-coil motif containing
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to golgi associated PDZ domain and
coiled-coil motif containing protein -
Strongylocentrotus purpuratus
Length = 579
Score = 31.1 bits (67), Expect = 4.5
Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1 MADERLVVLNRSDNLGFGFSLLG--EAGLPHVIYEIEENSPAARSGEV 46
+ D R V L + G G S+ G E G+P +I EI N PA R E+
Sbjct: 246 VGDIRTVTLVKEPEEGLGMSITGGKEHGVPILISEIHPNLPADRCQEL 293
>UniRef50_UPI0000D5573E Cluster: PREDICTED: similar to
Tyrosine-protein phosphatase non-receptor type 13
(Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1)
(PTP-BAS) (Protein-tyrosine phosphatase PTPL1)
(Fas-associated protein-tyrosine phosphatase 1) (FAP-1);
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein phosphatase non-receptor type 13
(Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1)
(PTP-BAS) (Protein-tyrosine phosphatase PTPL1)
(Fas-associated protein-tyrosine phosphatase 1) (FAP-1)
- Tribolium castaneum
Length = 768
Score = 31.1 bits (67), Expect = 4.5
Identities = 25/67 (37%), Positives = 35/67 (52%), Gaps = 10/67 (14%)
Query: 7 VVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPAARSG---------EVSMHSILWISQT 57
+ LNR N GFSL G AG+ +V + +S AAR G +V+ S+ +S T
Sbjct: 677 IELNRGWNSRLGFSLQGAAGVTYV-SAVHADSVAARDGRLKPGDRVIKVNDESVEHLSTT 735
Query: 58 KIIHYLR 64
+II LR
Sbjct: 736 EIIDLLR 742
>UniRef50_UPI000065EBB9 Cluster: Homolog of Homo sapiens "Splice
Isoform 2 of Atrophin-1 interacting protein 1; n=1;
Takifugu rubripes|Rep: Homolog of Homo sapiens "Splice
Isoform 2 of Atrophin-1 interacting protein 1 - Takifugu
rubripes
Length = 1431
Score = 31.1 bits (67), Expect = 4.5
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%)
Query: 7 VVLNRSDNLGFGFSLLGEAG---------LPHVIYEIEENSPAARSGEVSM-HSILWISQ 56
VV++R +N GFGF ++ +PH I I E SPA R G++ + IL ++
Sbjct: 1096 VVIHRKENEGFGFVIISSLNRPENTTIITVPHKIGRIIEGSPADRCGKLKVGDRILAVNG 1155
Query: 57 TKII 60
II
Sbjct: 1156 QSII 1159
>UniRef50_Q4S7I1 Cluster: Chromosome 13 SCAF14715, whole genome
shotgun sequence; n=3; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF14715, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1279
Score = 31.1 bits (67), Expect = 4.5
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%)
Query: 7 VVLNRSDNLGFGFSLLGEAG---------LPHVIYEIEENSPAARSGEVSM-HSILWISQ 56
VV++R +N GFGF ++ +PH I I E SPA R G++ + IL ++
Sbjct: 1167 VVIHRKENEGFGFVIISSLNRPENATVITVPHKIGRIIEGSPADRCGKLKVGDRILAVNG 1226
Query: 57 TKII 60
II
Sbjct: 1227 QSII 1230
>UniRef50_Q4RIG1 Cluster: Chromosome 11 SCAF15043, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 11
SCAF15043, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 906
Score = 30.7 bits (66), Expect = 5.9
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 6/44 (13%)
Query: 7 VVLNRSDNLGFGFSLLGEAG------LPHVIYEIEENSPAARSG 44
+ L+R DN GFGF +L +PH I I E SP R G
Sbjct: 663 ITLHRRDNEGFGFVILTSKSKPPYGMIPHKIGRIIEGSPTDRCG 706
>UniRef50_Q6NIS8 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium diphtheriae|Rep: Putative
uncharacterized protein - Corynebacterium diphtheriae
Length = 335
Score = 30.7 bits (66), Expect = 5.9
Identities = 10/39 (25%), Positives = 27/39 (69%), Gaps = 1/39 (2%)
Query: 29 HVIYEIEENSPAARSGEVSMHSILWISQTKIIHYLRSRI 67
++ Y+ E ++P + + E+ +H++LW+S + + + RS++
Sbjct: 268 NIFYDSEFDAPPSSNSELPLHTVLWLS-AETVTWARSQV 305
>UniRef50_Q29H53 Cluster: GA12994-PA; n=1; Drosophila
pseudoobscura|Rep: GA12994-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 999
Score = 30.7 bits (66), Expect = 5.9
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 7 VVLNRSDNLGFGFSLLGEAGLPHVIYEIEENSPAARSGEVSMHSILW-ISQTKIIHYLR 64
V L R+ G G S+ G + VI +++ SPA RSG + IL + Q + H+ R
Sbjct: 581 VKLLRAGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRAGDILLAVDQHPVQHFNR 639
>UniRef50_UPI0000F217A1 Cluster: PREDICTED: similar to membrane
associated guanylate kinase, WW and PDZ domain
containing 2; n=3; Danio rerio|Rep: PREDICTED: similar
to membrane associated guanylate kinase, WW and PDZ
domain containing 2 - Danio rerio
Length = 1227
Score = 30.3 bits (65), Expect = 7.8
Identities = 18/36 (50%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 13 DNLGFGFSLLG--EAGLPHVIYEIEENSPAARSGEV 46
+ GFGF +LG EA VI I ENSPA R G +
Sbjct: 752 EKTGFGFRILGGDEAVQAIVIGAIIENSPAERDGRL 787
>UniRef50_Q1DJZ9 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 531
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
Query: 16 GFGFSLLGEAGLPHVIYEIEENSPAARSGEVSMHSILW 53
GFG +L G+P +Y+ E ++P++R VSMH I++
Sbjct: 123 GFGIGIL-VTGIP--MYQAEASAPSSRGFMVSMHGIMF 157
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.135 0.388
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 85,596,007
Number of Sequences: 1657284
Number of extensions: 2853436
Number of successful extensions: 5680
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 5665
Number of HSP's gapped (non-prelim): 34
length of query: 78
length of database: 575,637,011
effective HSP length: 57
effective length of query: 21
effective length of database: 481,171,823
effective search space: 10104608283
effective search space used: 10104608283
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 65 (30.3 bits)
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