Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002474-TA|BGIBMGA002474-PA|IPR001590|Peptidase M12B,
ADAM/reprolysin
(349 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase wit... 589 e-167
UniRef50_UPI0000D554CF Cluster: PREDICTED: similar to ADAM metal... 179 9e-44
UniRef50_UPI0000DB7966 Cluster: PREDICTED: similar to ADAM metal... 165 2e-39
UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38; Euteleostomi... 133 7e-30
UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep... 116 7e-25
UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome sh... 108 2e-22
UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-)... 106 1e-21
UniRef50_Q4SHJ1 Cluster: Chromosome 5 SCAF14581, whole genome sh... 105 2e-21
UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32; Euteleostomi... 104 4e-21
UniRef50_Q14F51 Cluster: COMPase; n=15; Euteleostomi|Rep: COMPas... 103 9e-21
UniRef50_Q9UKP4 Cluster: ADAMTS-7 precursor; n=23; Euteleostomi|... 103 9e-21
UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome sh... 101 4e-20
UniRef50_UPI000069E320 Cluster: ADAM metallopeptidase with throm... 98 3e-19
UniRef50_UPI00004CFC4D Cluster: ADAM metallopeptidase with throm... 98 3e-19
UniRef50_A2RRN9 Cluster: ADAMTS12 protein; n=5; Eumetazoa|Rep: A... 97 5e-19
UniRef50_P58397 Cluster: ADAMTS-12 precursor; n=23; Euteleostomi... 97 5e-19
UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B ... 96 1e-18
UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whol... 95 3e-18
UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|R... 95 3e-18
UniRef50_Q9P2N4 Cluster: ADAMTS-9 precursor; n=50; Euteleostomi|... 94 4e-18
UniRef50_Q9UKP5 Cluster: ADAMTS-6 precursor; n=5; Tetrapoda|Rep:... 93 7e-18
UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona intesti... 92 2e-17
UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20; Euteleostomi|... 92 2e-17
UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM metal... 90 9e-17
UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23; Euteleostomi... 89 1e-16
UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19; Euteleostomi... 89 2e-16
UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Re... 88 3e-16
UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome sh... 87 6e-16
UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64; Euteleostomi... 87 6e-16
UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31; Euteleostomi|... 86 1e-15
UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADA... 85 3e-15
UniRef50_UPI00015B5B5C Cluster: PREDICTED: similar to adamts-7; ... 83 1e-14
UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella ve... 82 2e-14
UniRef50_Q3ULV2 Cluster: Mammary gland RCB-0527 Jyg-MC(B) cDNA, ... 81 3e-14
UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA;... 81 4e-14
UniRef50_Q9W493 Cluster: CG4096-PA; n=3; Sophophora|Rep: CG4096-... 80 7e-14
UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella ve... 80 7e-14
UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6 va... 79 2e-13
UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9 p... 79 2e-13
UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamt... 79 2e-13
UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-... 78 4e-13
UniRef50_UPI0000E46B78 Cluster: PREDICTED: similar to ADAM metal... 77 5e-13
UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n... 77 5e-13
UniRef50_A7S1V9 Cluster: Predicted protein; n=1; Nematostella ve... 77 9e-13
UniRef50_UPI00015B5FBF Cluster: PREDICTED: similar to a disinteg... 76 1e-12
UniRef50_A7RW19 Cluster: Predicted protein; n=1; Nematostella ve... 76 1e-12
UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep... 76 1e-12
UniRef50_Q4RSP7 Cluster: Chromosome 12 SCAF14999, whole genome s... 74 5e-12
UniRef50_Q19791 Cluster: ADAMTS family gon-1 precursor; n=3; cel... 73 1e-11
UniRef50_UPI0000D5652D Cluster: PREDICTED: similar to ADAM metal... 73 1e-11
UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep: ... 73 1e-11
UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7; ... 72 2e-11
UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome sh... 72 3e-11
UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p... 72 3e-11
UniRef50_UPI0000DB737E Cluster: PREDICTED: similar to ADAMTS-9 p... 71 6e-11
UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona intesti... 69 1e-10
UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease ... 69 1e-10
UniRef50_UPI0000DA2EEE Cluster: PREDICTED: similar to ADAMTS-8 p... 69 2e-10
UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome s... 69 2e-10
UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep:... 68 3e-10
UniRef50_A7SQN1 Cluster: Predicted protein; n=1; Nematostella ve... 68 4e-10
UniRef50_UPI0000F1ED1E Cluster: PREDICTED: hypothetical protein;... 66 1e-09
UniRef50_UPI0000DB717B Cluster: PREDICTED: similar to ADAMTS-7 p... 66 2e-09
UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12 ... 65 2e-09
UniRef50_Q4RSH9 Cluster: Chromosome 13 SCAF15000, whole genome s... 64 5e-09
UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-... 63 1e-08
UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep:... 63 1e-08
UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1 p... 62 2e-08
UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella ve... 62 2e-08
UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-... 62 2e-08
UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13; ... 61 4e-08
UniRef50_UPI0000D556A5 Cluster: PREDICTED: similar to ADAMTS-12 ... 60 6e-08
UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella ve... 60 8e-08
UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von Wil... 59 1e-07
UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella ve... 59 1e-07
UniRef50_UPI0000D56749 Cluster: PREDICTED: similar to CG3622-PB,... 58 3e-07
UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Re... 58 3e-07
UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whol... 57 8e-07
UniRef50_UPI0000F2AE75 Cluster: PREDICTED: similar to a disinteg... 56 1e-06
UniRef50_UPI0000586C6C Cluster: PREDICTED: similar to ADAMTS6 va... 53 1e-05
UniRef50_Q9W1Z6 Cluster: CG3622-PB, isoform B; n=5; Sophophora|R... 52 3e-05
UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella ve... 50 1e-04
UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM metal... 49 2e-04
UniRef50_Q9H2U9 Cluster: ADAM 7 precursor; n=24; Mammalia|Rep: A... 48 4e-04
UniRef50_UPI0001556104 Cluster: PREDICTED: similar to aggrecanas... 48 5e-04
UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice ... 47 6e-04
UniRef50_Q5BVG6 Cluster: SJCHGC06709 protein; n=1; Schistosoma j... 47 6e-04
UniRef50_A7SQN3 Cluster: Predicted protein; n=1; Nematostella ve... 47 6e-04
UniRef50_UPI000155622B Cluster: PREDICTED: similar to ADAM metal... 47 8e-04
UniRef50_Q177Y0 Cluster: Adam; n=2; Culicidae|Rep: Adam - Aedes ... 47 8e-04
UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_A7SM43 Cluster: Predicted protein; n=1; Nematostella ve... 45 0.003
UniRef50_P58459-3 Cluster: Isoform 3 of P58459 ; n=3; Murinae|Re... 44 0.006
UniRef50_A7RTF7 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.006
UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleavi... 44 0.008
UniRef50_Q4RN96 Cluster: Chromosome 1 SCAF15015, whole genome sh... 44 0.008
UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.010
UniRef50_P20165 Cluster: Trimerelysin-2; n=46; Viperidae|Rep: Tr... 43 0.010
UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome s... 43 0.014
UniRef50_A7SIV2 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.018
UniRef50_O43184 Cluster: ADAM 12 precursor; n=44; Euteleostomi|R... 42 0.018
UniRef50_UPI0000E8086C Cluster: PREDICTED: similar to metallopro... 42 0.032
UniRef50_UPI0000F2B1C1 Cluster: PREDICTED: similar to ADAM metal... 41 0.055
UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.055
UniRef50_P83512 Cluster: Hemorrhagic metalloproteinase BaP1; n=5... 41 0.055
UniRef50_Q13443 Cluster: ADAM 9 precursor; n=35; Euteleostomi|Re... 41 0.055
UniRef50_Q9R159 Cluster: ADAM 25 precursor; n=5; Mus musculus|Re... 40 0.073
UniRef50_UPI0000E25573 Cluster: PREDICTED: ADAM metallopeptidase... 40 0.097
UniRef50_O12960 Cluster: ADAM 13; n=3; Xenopus|Rep: ADAM 13 - Xe... 40 0.097
UniRef50_Q9BZ11 Cluster: ADAM 33 precursor; n=29; Tetrapoda|Rep:... 40 0.097
UniRef50_UPI0000F1E743 Cluster: PREDICTED: similar to ADAM13; n=... 40 0.13
UniRef50_UPI0000E81538 Cluster: PREDICTED: hypothetical protein;... 39 0.22
UniRef50_UPI0000660B5D Cluster: Homolog of Homo sapiens "Splice ... 38 0.52
UniRef50_Q4SEB0 Cluster: Chromosome 2 SCAF14623, whole genome sh... 38 0.52
UniRef50_UPI0000D9BA61 Cluster: PREDICTED: similar to a disinteg... 37 0.68
UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5; Caenorhabdit... 37 0.68
UniRef50_Q90495 Cluster: Ecarin precursor; n=151; Colubroidea|Re... 37 0.68
UniRef50_UPI0000F2C443 Cluster: PREDICTED: similar to cysteine-r... 36 1.2
UniRef50_Q2VYF6 Cluster: Metalloproteinase 12-like protein; n=3;... 36 1.2
UniRef50_Q8TC27 Cluster: ADAM 32 precursor; n=22; Eutheria|Rep: ... 36 1.2
UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1; Rh... 36 1.6
UniRef50_Q4RE58 Cluster: Chromosome 2 SCAF15135, whole genome sh... 36 2.1
UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to metallopro... 35 2.7
UniRef50_UPI0000F2BB07 Cluster: PREDICTED: similar to epididymal... 35 2.7
UniRef50_UPI0000DB7008 Cluster: PREDICTED: similar to CG3622-PB,... 35 3.6
UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas monolakensi... 35 3.6
UniRef50_Q64S53 Cluster: Putative uncharacterized protein; n=2; ... 34 4.8
UniRef50_UPI00001CC78C Cluster: PREDICTED: similar to ADAM metal... 34 6.3
UniRef50_Q5ZRV1 Cluster: NADH dehydrogenase I, N subunit; n=4; L... 33 8.4
UniRef50_A1GFB5 Cluster: 3-Oxoacyl-(Acyl-carrier-protein (ACP)) ... 33 8.4
UniRef50_A0UVG5 Cluster: Transcriptional regulator, AraC family;... 33 8.4
UniRef50_Q16GK9 Cluster: Adam; n=2; Culicidae|Rep: Adam - Aedes ... 33 8.4
UniRef50_A7SIV0 Cluster: Predicted protein; n=1; Nematostella ve... 33 8.4
>UniRef50_Q5W7F4 Cluster: A disintegrin and metalloproteinase with
thrombospondin motifs 1; n=1; Bombyx mori|Rep: A
disintegrin and metalloproteinase with thrombospondin
motifs 1 - Bombyx mori (Silk moth)
Length = 1007
Score = 589 bits (1455), Expect = e-167
Identities = 277/290 (95%), Positives = 277/290 (95%)
Query: 60 AQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQV 119
AQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQV
Sbjct: 38 AQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQV 97
Query: 120 GGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHP 179
GGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVI PTSHVHP
Sbjct: 98 GGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIDLDLDFDEDDDLLPTSHVHP 157
Query: 180 RHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVS 239
RHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVS
Sbjct: 158 RHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVS 217
Query: 240 AIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWD 299
AIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWD
Sbjct: 218 AIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWD 277
Query: 300 ATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
ATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL
Sbjct: 278 ATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 327
>UniRef50_UPI0000D554CF Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 3
proprotein; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to ADAM metallopeptidase with thrombospondin
type 1 motif, 3 proprotein - Tribolium castaneum
Length = 1061
Score = 179 bits (436), Expect = 9e-44
Identities = 115/299 (38%), Positives = 161/299 (53%), Gaps = 37/299 (12%)
Query: 88 ECQFFTGRVLHEEG-SAVTVTECDGQLYGLLQVGGEEFVLQPTR-TQEKHVLRRRDVTHS 145
+C + G V E S VT C + G + VG F LQPT TQ +H L R+ +T S
Sbjct: 100 QCDYKLGVVRSLETLSRAAVTLCGRYVIGYIAVGDLVFFLQPTNGTQGEHRLDRQAITKS 159
Query: 146 --ERSAE-------------YNLTGDTVIXXXXXXXXXXXXXPTSHVHP----------R 180
+R ++ +NLTGD + + R
Sbjct: 160 RLKRHSDDIYFEQPQPEQWLFNLTGDVIDIEGSTGSIRDNASEEDDLEEKFTTSPLLSWR 219
Query: 181 HSDHSDKE--YFHDMHLF------RRPASGV-KGLWLELAIVADNTMLKFHGRERVKHYI 231
D+E YF+D R+ S + WLE+A+ D+T+++FHG+++V+ Y+
Sbjct: 220 REQLEDEELGYFYDTAWTADAPKTRKSGSSLLPPRWLEIALAVDHTLIQFHGKDKVEQYV 279
Query: 232 LALMNIVSAIFNDPSLGSNITLVINKLFLYED-KDIILKYGNIKKSLEAINKWNYRHLMK 290
LALMNIV+AI+ DPSL +N+ LV+ +L LYE K I++ G+ KKSLE N WN R
Sbjct: 280 LALMNIVNAIYQDPSLEANMRLVVTRLLLYEHRKQSIVRPGDAKKSLENANSWNSRLHAS 339
Query: 291 LPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
L + D +WLTRS +GGPSG+APV G C RS A++RDEGLTSAF+IAHE+AH+
Sbjct: 340 LAPDESHHDIAVWLTRSDIGGPSGYAPVAGACDPKRSCALNRDEGLTSAFIIAHEMAHV 398
>UniRef50_UPI0000DB7966 Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 3
proprotein; n=2; Apis mellifera|Rep: PREDICTED: similar
to ADAM metallopeptidase with thrombospondin type 1
motif, 3 proprotein - Apis mellifera
Length = 856
Score = 165 bits (400), Expect = 2e-39
Identities = 80/144 (55%), Positives = 106/144 (73%), Gaps = 5/144 (3%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK-D 265
WLEL I AD +++ FHG RV+ YILAL+NIVSAI+ DPSL SN+ LVI ++ LY +K D
Sbjct: 276 WLELGIAADYSVIDFHGI-RVQQYILALLNIVSAIYMDPSLDSNMVLVIVRMILYAEKRD 334
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKT 325
+++ G+ K+SLE +NKWN + L D +WLTR +GGPSG+APV GVC +
Sbjct: 335 GMVRRGDAKRSLENVNKWNRK---MLSSADVNHDVAVWLTRLDIGGPSGYAPVSGVCDPS 391
Query: 326 RSAAIDRDEGLTSAFVIAHELAHL 349
RS A++RDEGLTSAF+IAHE+AH+
Sbjct: 392 RSCALNRDEGLTSAFIIAHEVAHI 415
Score = 33.9 bits (74), Expect = 6.3
Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 89 CQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVL 137
C G + +E S V VT C+G +Y ++ F +QP T +HV+
Sbjct: 105 CDLRRGSLEGDESSFVVVTICEGDVYAMMLTNQRSFFVQPL-TNGEHVM 152
>UniRef50_Q8WXS8 Cluster: ADAMTS-14 precursor; n=38;
Euteleostomi|Rep: ADAMTS-14 precursor - Homo sapiens
(Human)
Length = 1223
Score = 133 bits (321), Expect = 7e-30
Identities = 84/272 (30%), Positives = 141/272 (51%), Gaps = 17/272 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAP 317
+ Y +++ GN +SLE + +W + + P + D ++LTR GPSG+AP
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDF-GPSGYAP 371
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
V G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 372 VTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 403
>UniRef50_O95450 Cluster: ADAMTS-2 precursor; n=49; Eukaryota|Rep:
ADAMTS-2 precursor - Homo sapiens (Human)
Length = 1211
Score = 116 bits (280), Expect = 7e-25
Identities = 80/259 (30%), Positives = 135/259 (52%), Gaps = 20/259 (7%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTR---TQEKHVLRRRDVTHSERSAEYNLTGD 156
E S+V ++ CDG L GL+++ EEF ++P ++ R V + L G
Sbjct: 166 EASSVALSNCDG-LAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGP 224
Query: 157 TVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADN 216
+ V H++ S + RR A+ +E+ + D+
Sbjct: 225 QALDTGASLDSLDSLSRALGVLEEHANSSRRRA-------RRHAAD-DDYNIEVLLGVDD 276
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFL--YEDKDIILKYGNIK 274
++++FHG+E V+ Y+L LMNIV+ I++D SLG++I +V+ ++ L Y +++ GN
Sbjct: 277 SVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPS 336
Query: 275 KSLEAINKWNYRHLMKLPE-GSTGW-DATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAI 330
+SLE + +W Y L + P+ G + D I+LTR G G G+APV G+C RS +
Sbjct: 337 QSLENVCRWAY--LQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTL 394
Query: 331 DRDEGLTSAFVIAHELAHL 349
+ ++G +SAFV+AHE H+
Sbjct: 395 NHEDGFSSAFVVAHETGHV 413
>UniRef50_Q4T2J1 Cluster: Chromosome 1 SCAF10257, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF10257, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1125
Score = 108 bits (260), Expect = 2e-22
Identities = 52/146 (35%), Positives = 92/146 (63%), Gaps = 4/146 (2%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFL--YEDKD 265
+E+ + D+++++FHG+E V+ Y+L LMNIV+ I++D SLG+ I +V+ ++ + Y
Sbjct: 39 IEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDQSLGAKINVVLVRIIMLGYGKSM 98
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGFAPVGGVCT 323
+++ GN +SLE + +W + + + D I+LTR + G G G+APV G+C
Sbjct: 99 SLIELGNPSQSLENVCRWAFLQQKQDTGDAEYHDHAIFLTRQEFGPTGMQGYAPVTGMCH 158
Query: 324 KTRSAAIDRDEGLTSAFVIAHELAHL 349
RS ++ ++G +SAFV+AHE H+
Sbjct: 159 PVRSCTLNHEDGFSSAFVVAHETGHV 184
>UniRef50_UPI00015A6CA9 Cluster: ADAMTS-1 precursor (EC 3.4.24.-) (A
disintegrin and metalloproteinase with thrombospondin
motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1).; n=1; Danio
rerio|Rep: ADAMTS-1 precursor (EC 3.4.24.-) (A
disintegrin and metalloproteinase with thrombospondin
motifs 1) (ADAM-TS 1) (ADAM-TS1) (METH-1). - Danio rerio
Length = 886
Score = 106 bits (254), Expect = 1e-21
Identities = 82/268 (30%), Positives = 125/268 (46%), Gaps = 18/268 (6%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAE 150
FF+G V +E S+ + C G L+G VGGEE+ +QP + RD TH+ R
Sbjct: 96 FFSGTVNGDELSSAAINLCKG-LHGGFSVGGEEYFIQPENSTG--AATDRD-THTIRRRT 151
Query: 151 YNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSD-KEYFHDM--HLFRRPASGVKGLW 207
+ + T H HS S+ K H H RR S + +
Sbjct: 152 PGILAEE--SGSKCGVNEEEERVTEKPHTTHSKPSESKGLCHPTAHHRSRRFVSTPR--Y 207
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
LE+ IVAD +M +FHG + +K Y+L +M + S ++ P++ ++ITL + KL + D++
Sbjct: 208 LEIMIVADQSMAEFHGAQ-LKPYLLTIMAVASRLYRHPTIHNSITLAVVKLLVVHDEEHG 266
Query: 268 LKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGV 321
N +L + +W +H +D + TR L G G A VG
Sbjct: 267 PHVSTNAALTLRSFCQWQKQHNQPSDRHPEHYDTAVLFTRKDLCGAHSCDTLGMADVGTA 326
Query: 322 CTKTRSAAIDRDEGLTSAFVIAHELAHL 349
C RS +I D+GL +AF +AHEL H+
Sbjct: 327 CDPDRSCSIIEDDGLQAAFTVAHELGHV 354
>UniRef50_Q4SHJ1 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; root|Rep: Chromosome 5 SCAF14581,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1689
Score = 105 bits (251), Expect = 2e-21
Identities = 84/274 (30%), Positives = 127/274 (46%), Gaps = 21/274 (7%)
Query: 92 FTGRVLHEEG--SAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHS--ER 147
F G V EE ++ CDG L GL ++ GEEF +QP +E + H+ +R
Sbjct: 112 FLGEVWDEEAVKGRAAISACDG-LTGLFRLSGEEFFIQPL--EESSLQSSAPQAHAIYKR 168
Query: 148 SAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSD-HSDKEYFHDMHLFRR----PASG 202
A +G V+ + H +D +E + L +R S
Sbjct: 169 HAAPP-SGPHVLQPLAGKQTLNGTCGNKNSHHSLADIERQRERWERRRLRKRRRIRQRSV 227
Query: 203 VKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE 262
K W+E +VAD M+++HG V++YILA+MNIV+ +F D S+G+ I +V+ +L L E
Sbjct: 228 SKEKWVETLVVADPKMVEYHGSHSVENYILAVMNIVAGLFGDASIGNAINVVVVRLILLE 287
Query: 263 -DKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGG-------PSG 314
D+D + + SL + KW + K + D + LTR + G
Sbjct: 288 KDEDDLKITHHADNSLLSFCKWQKKLNTKGDDHPLHHDVAVLLTRKDICAAVNVPCETLG 347
Query: 315 FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ V G+C RS +I D GL AF +AHEL H
Sbjct: 348 LSHVAGMCQAHRSCSISEDTGLPVAFTVAHELGH 381
>UniRef50_Q9H324 Cluster: ADAMTS-10 precursor; n=32;
Euteleostomi|Rep: ADAMTS-10 precursor - Homo sapiens
(Human)
Length = 1103
Score = 104 bits (249), Expect = 4e-21
Identities = 59/157 (37%), Positives = 91/157 (57%), Gaps = 15/157 (9%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY-EDKD 265
++E +VAD M+ +HGR V+ Y+LA+MNIV+ +F D SLGS + +++ +L L ED+
Sbjct: 240 YVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQP 299
Query: 266 IILKYGNIKKSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQL-------GG 311
+ + KSL++ KW N+ H +PE G D + +TR + G
Sbjct: 300 TLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCG 359
Query: 312 PSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G APVGG+C + RS +++ D GL +AF IAHE+ H
Sbjct: 360 TLGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGH 396
>UniRef50_Q14F51 Cluster: COMPase; n=15; Euteleostomi|Rep: COMPase -
Homo sapiens (Human)
Length = 1686
Score = 103 bits (246), Expect = 9e-21
Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 140 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 198
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + R ++ + L R V K W+E +VAD
Sbjct: 199 ----SAPSTCGVQVYP--ELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 252
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 253 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADN 312
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 313 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 372
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 373 SINEDTGLPLAFTVAHELGH 392
>UniRef50_Q9UKP4 Cluster: ADAMTS-7 precursor; n=23;
Euteleostomi|Rep: ADAMTS-7 precursor - Homo sapiens
(Human)
Length = 997
Score = 103 bits (246), Expect = 9e-21
Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 140 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 198
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + R ++ + L R V K W+E +VAD
Sbjct: 199 ----SAPSTCGVQVYP--ELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 252
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 253 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADN 312
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 313 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 372
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 373 SINEDTGLPLAFTVAHELGH 392
>UniRef50_Q4S903 Cluster: Chromosome 7 SCAF14703, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF14703, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 875
Score = 101 bits (241), Expect = 4e-20
Identities = 74/268 (27%), Positives = 126/268 (47%), Gaps = 19/268 (7%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTR---TQEKHVLRRRDVTHSER 147
F++G V + S ++ C G L G G E+ + P + T+ H++RRR T+S +
Sbjct: 69 FYSGYVNSDRESYAALSLCKG-LRGAFGFQGWEYFISPVQNRSTESAHIIRRR--TNSNQ 125
Query: 148 SAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLW 207
+ N T + H+ + + + +R AS + +
Sbjct: 126 --KLNSTSRCAVDSDLSLKAAKSLAKYKHLED--GSNVTETVLRKIGRAKRFASVPR--Y 179
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E +VAD++M++FHG + +KHY+L LM++ + ++ PS+ + I + + K+ + ++D
Sbjct: 180 VETLVVADSSMVQFHGSD-LKHYLLTLMSVAARLYKHPSILNFINIAVVKIVIISEEDKG 238
Query: 268 LKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGGV 321
K GN +L W + + WD I TR L G S G A VG +
Sbjct: 239 PKVSGNAAMTLRNFCTWQKKLNKNTDKHPEYWDTAILFTRQDLCGASTCDTLGMADVGTM 298
Query: 322 CTKTRSAAIDRDEGLTSAFVIAHELAHL 349
C RS ++ D+GL SAF AHEL H+
Sbjct: 299 CDSKRSCSVIEDDGLPSAFTTAHELGHV 326
>UniRef50_UPI000069E320 Cluster: ADAM metallopeptidase with
thrombospondin type 1 motif, 7 preproprotein; n=1;
Xenopus tropicalis|Rep: ADAM metallopeptidase with
thrombospondin type 1 motif, 7 preproprotein - Xenopus
tropicalis
Length = 800
Score = 98.3 bits (234), Expect = 3e-19
Identities = 55/159 (34%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 198 RPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINK 257
R S K W+E +VAD+ M+++HG + V++Y+L +MN+V+ +F+D S+G+ I +VI +
Sbjct: 236 RTRSISKEKWVETLVVADHKMVEYHGSDNVENYVLTVMNMVAGLFHDASIGNRINIVIVR 295
Query: 258 LFLYEDKDIILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS--- 313
L L E ++ LK + +L + KW MK E D + LTR +
Sbjct: 296 LILLESEEEDLKITHHADNTLRSFCKWQKNLNMKGEEHPQHHDVAVLLTRKDICAAMNRP 355
Query: 314 ----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + V G+C RS I+ D GL +AF + HEL H
Sbjct: 356 CETLGLSHVSGMCQPHRSCNINEDTGLPTAFTVTHELGH 394
>UniRef50_UPI00004CFC4D Cluster: ADAM metallopeptidase with
thrombospondin type 1 motif, 7 preproprotein; n=2;
Xenopus tropicalis|Rep: ADAM metallopeptidase with
thrombospondin type 1 motif, 7 preproprotein - Xenopus
tropicalis
Length = 1551
Score = 98.3 bits (234), Expect = 3e-19
Identities = 55/159 (34%), Positives = 86/159 (54%), Gaps = 8/159 (5%)
Query: 198 RPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINK 257
R S K W+E +VAD+ M+++HG + V++Y+L +MN+V+ +F+D S+G+ I +VI +
Sbjct: 200 RTRSISKEKWVETLVVADHKMVEYHGSDNVENYVLTVMNMVAGLFHDASIGNRINIVIVR 259
Query: 258 LFLYEDKDIILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS--- 313
L L E ++ LK + +L + KW MK E D + LTR +
Sbjct: 260 LILLESEEEDLKITHHADNTLRSFCKWQKNLNMKGEEHPQHHDVAVLLTRKDICAAMNRP 319
Query: 314 ----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + V G+C RS I+ D GL +AF + HEL H
Sbjct: 320 CETLGLSHVSGMCQPHRSCNINEDTGLPTAFTVTHELGH 358
>UniRef50_A2RRN9 Cluster: ADAMTS12 protein; n=5; Eumetazoa|Rep:
ADAMTS12 protein - Homo sapiens (Human)
Length = 1509
Score = 97.5 bits (232), Expect = 5e-19
Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 10/162 (6%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLV 254
L RR S K W+E +VAD M+++HG E V+ YIL +MN+V+ +F++PS+G+ I +V
Sbjct: 237 LSRRSIS--KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIV 294
Query: 255 INKLFLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---- 309
+ +L L E+++ LK + +K+L + KW K D + LTR +
Sbjct: 295 VVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGF 354
Query: 310 GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
P G + + G+C RS I+ D GL AF IAHEL H
Sbjct: 355 NRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGH 396
>UniRef50_P58397 Cluster: ADAMTS-12 precursor; n=23;
Euteleostomi|Rep: ADAMTS-12 precursor - Homo sapiens
(Human)
Length = 1593
Score = 97.5 bits (232), Expect = 5e-19
Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 10/162 (6%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLV 254
L RR S K W+E +VAD M+++HG E V+ YIL +MN+V+ +F++PS+G+ I +V
Sbjct: 237 LSRRSIS--KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIV 294
Query: 255 INKLFLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---- 309
+ +L L E+++ LK + +K+L + KW K D + LTR +
Sbjct: 295 VVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGF 354
Query: 310 GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
P G + + G+C RS I+ D GL AF IAHEL H
Sbjct: 355 NRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGH 396
>UniRef50_Q68SA9 Cluster: ADAMTS7B; n=8; Tetrapoda|Rep: ADAMTS7B -
Mus musculus (Mouse)
Length = 1641
Score = 96.3 bits (229), Expect = 1e-18
Identities = 68/258 (26%), Positives = 118/258 (45%), Gaps = 20/258 (7%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVI 159
EG ++ CDG L G+ Q+ E++ ++P H++ Y G
Sbjct: 130 EGGFAAISACDG-LRGVFQLSNEDYFIEPLDGVSAQP------GHAQPHVVYKHQGSR-- 180
Query: 160 XXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADNTM 218
T + +E++ RR V K W+E +VAD+ M
Sbjct: 181 --KQAQQGDSRPSGTCGMQVPPDLEQQREHWEQQQQKRRQQRSVSKEKWVETLVVADSKM 238
Query: 219 LKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKKSL 277
+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L + ED++ LK + +++L
Sbjct: 239 VEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHISIVRLIILEDEEKDLKITHHAEETL 298
Query: 278 EAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSAAI 330
+ +W +K + D I LTR L G + V G+C S ++
Sbjct: 299 KNFCRWQKNINIKGDDHPQHHDTAILLTRKDLCASMNQPCETLGLSHVSGLCHPQLSCSV 358
Query: 331 DRDEGLTSAFVIAHELAH 348
D G+ AF +AHEL H
Sbjct: 359 SEDTGMPLAFTVAHELGH 376
>UniRef50_Q4S8G2 Cluster: Chromosome undetermined SCAF14706, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14706,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1151
Score = 94.7 bits (225), Expect = 3e-18
Identities = 57/153 (37%), Positives = 86/153 (56%), Gaps = 9/153 (5%)
Query: 203 VKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE 262
V GL +E +VAD ML+ HGR+ V Y+L +MN+VS++F D ++G++I +V+ L L E
Sbjct: 269 VGGLNVETLVVADRKMLEKHGRDNVTTYVLTVMNMVSSLFKDGTIGTDINIVVVGLLLLE 328
Query: 263 DKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGS------TGWDATIWLTRSQLGGPSGF 315
+ + L + +SL + +W L K + TG D W +++ GF
Sbjct: 329 EDPLGLTISHHADQSLNSFCQWQSGLLGKGGKRHDHAVLLTGLDICSW--KNEPCDTLGF 386
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
AP+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 387 APISGMCSKYRSCTINEDTGLGLAFTIAHESGH 419
>UniRef50_Q5IR89 Cluster: ADAMTS6 variant 2; n=34; Euteleostomi|Rep:
ADAMTS6 variant 2 - Homo sapiens (Human)
Length = 1117
Score = 94.7 bits (225), Expect = 3e-18
Identities = 79/301 (26%), Positives = 141/301 (46%), Gaps = 39/301 (12%)
Query: 76 KENKAIRSPYYKECQFFTGRVLHEEGSA-VTVTECDGQLYGLLQVGGEEFVLQPTR--TQ 132
K+ + + C + TG + + + V ++ C G L+G++ EE+ ++P + T+
Sbjct: 118 KDGPQWKHDFLDNCHY-TGYLQDQRSTTKVALSNCVG-LHGVIATEDEEYFIEPLKNTTE 175
Query: 133 EK----------HVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHS 182
+ HV+ ++ +++ G + SH P ++
Sbjct: 176 DSKHFSYENGHPHVIYKKSALQQRHLYDHSHCGVSDFTRSGKPWWLNDTSTVSHSLPINN 235
Query: 183 DHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIF 242
H H H +R S + ++E +VAD M+ +HGR+ ++HYIL++MNIV+ ++
Sbjct: 236 TH-----IH--HRQKRSVSIER--FVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLY 286
Query: 243 NDPSLGSNITLVINKLF-LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGST----- 296
D SLG+ + +++ +L L ED+ + + KSL++ KW L +G+T
Sbjct: 287 RDSSLGNVVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENG 346
Query: 297 --GWDATIWLTRSQL-------GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELA 347
D + +TR + G G A V G+C RS +I+ D GL SAF IAHE+
Sbjct: 347 IAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIG 406
Query: 348 H 348
H
Sbjct: 407 H 407
>UniRef50_Q9P2N4 Cluster: ADAMTS-9 precursor; n=50;
Euteleostomi|Rep: ADAMTS-9 precursor - Homo sapiens
(Human)
Length = 1935
Score = 94.3 bits (224), Expect = 4e-18
Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDKD 265
++E+ +VADN M+ +HG E ++HYIL LM+IV++I+ DPS+G+ I +VI N + ++ ++D
Sbjct: 294 FVEVLVVADNRMVSYHG-ENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNEQD 352
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N + +L+ +W +H P G D + LTR + G A +G
Sbjct: 353 GPSISFNAQTTLKNFCQW--QHSKNSP-GGIHHDTAVLLTRQDICRAHDKCDTLGLAELG 409
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS +I D GL++AF IAHEL H+
Sbjct: 410 TICDPYRSCSISEDSGLSTAFTIAHELGHV 439
>UniRef50_Q9UKP5 Cluster: ADAMTS-6 precursor; n=5; Tetrapoda|Rep:
ADAMTS-6 precursor - Homo sapiens (Human)
Length = 860
Score = 93.5 bits (222), Expect = 7e-18
Identities = 58/174 (33%), Positives = 94/174 (54%), Gaps = 16/174 (9%)
Query: 191 HDMHLFRRPASGVK-GLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS 249
++ H+ R V ++E +VAD M+ +HGR+ ++HYIL++MNIV+ ++ D SLG+
Sbjct: 234 NNTHIHHRQKRSVSIERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN 293
Query: 250 NITLVINKLF-LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGST-------GWDAT 301
+ +++ +L L ED+ + + KSL++ KW L +G+T D
Sbjct: 294 VVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNA 353
Query: 302 IWLTRSQL-------GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ +TR + G G A V G+C RS +I+ D GL SAF IAHE+ H
Sbjct: 354 VLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIVH 407
>UniRef50_Q1RLE7 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 1030
Score = 92.3 bits (219), Expect = 2e-17
Identities = 51/148 (34%), Positives = 86/148 (58%), Gaps = 6/148 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF-LYEDKD 265
++E +VAD +M++ HG + ++HYIL LM + + +F+ PSLGS I++ + K+ L+ED D
Sbjct: 259 YIETLVVADASMVEEHGDD-LEHYILTLMMVANRVFSHPSLGSAISISVVKIMVLHEDSD 317
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGGV 321
+ + +L W RH +D I LTR+ L G + G A VG +
Sbjct: 318 GPRITQHAQHTLREFCSWQKRHNTPDDSDPQHYDLAILLTRTNLCGDTCATLGLAEVGTM 377
Query: 322 CTKTRSAAIDRDEGLTSAFVIAHELAHL 349
C++ S A+ D+GL++++ IAHE+ H+
Sbjct: 378 CSRRHSCAVIEDDGLSASYTIAHEVGHV 405
>UniRef50_Q9UNA0 Cluster: ADAMTS-5 precursor; n=20;
Euteleostomi|Rep: ADAMTS-5 precursor - Homo sapiens
(Human)
Length = 930
Score = 91.9 bits (218), Expect = 2e-17
Identities = 54/159 (33%), Positives = 88/159 (55%), Gaps = 7/159 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD +M + +GR ++HY+L L +I + +++ S+ ++I L +
Sbjct: 258 RRRRSISRARQVELLLVADASMARLYGRG-LQHYLLTLASIANRLYSHASIENHIRLAVV 316
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-- 313
K+ + DKD L+ N +L+ KW ++H + +DA I TR L G
Sbjct: 317 KVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSC 376
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C+ RS A+ D+GL +AF +AHE+ HL
Sbjct: 377 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHL 415
>UniRef50_UPI0000E45C7D Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 16
preproprotein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to ADAM metallopeptidase with
thrombospondin type 1 motif, 16 preproprotein -
Strongylocentrotus purpuratus
Length = 1202
Score = 89.8 bits (213), Expect = 9e-17
Identities = 53/150 (35%), Positives = 82/150 (54%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +V D M+K HG +++ Y+L + N+V+ +F D SLG I +++ L L ED
Sbjct: 273 YVETLVVVDKHMIKKHGSDKITAYVLTIFNMVAKLFRDSSLGHTINMMLVSLMLLEDDQP 332
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS---GFAPV 318
L + +SL + +W + + P G T D +I LT + + P GFAP+
Sbjct: 333 GLTISHHADRSLNSFCQW--QSTLTTPNG-THHDHSILLTGNDICSWKNEPCDTLGFAPI 389
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GG+C+K RS I+ D GL AF +AHE H
Sbjct: 390 GGMCSKYRSCTINEDTGLGLAFTVAHESGH 419
>UniRef50_Q8TE58 Cluster: ADAMTS-15 precursor; n=23;
Euteleostomi|Rep: ADAMTS-15 precursor - Homo sapiens
(Human)
Length = 950
Score = 89.4 bits (212), Expect = 1e-16
Identities = 75/269 (27%), Positives = 114/269 (42%), Gaps = 14/269 (5%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDV-TH--SER 147
F++G V E S V+ C G L G G E+V+ P +R H R
Sbjct: 102 FYSGDVNAEPDSFAAVSLCGG-LRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRR 160
Query: 148 SAEYNLTGD-TVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGL 206
+GD T PR + + +R S +
Sbjct: 161 GVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPR-- 218
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M+KFHG + ++HY+L L+ + ++ PS+ + I +V+ K+ L D+D
Sbjct: 219 YVETLVVADESMVKFHGAD-LEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDS 277
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
K GN +L W + + WD I TR L G + G A VG
Sbjct: 278 GPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGT 337
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS ++ D+GL SAF AHEL H+
Sbjct: 338 MCDPKRSCSVIEDDGLPSAFTTAHELGHV 366
>UniRef50_Q8TE56 Cluster: ADAMTS-17 precursor; n=19;
Euteleostomi|Rep: ADAMTS-17 precursor - Homo sapiens
(Human)
Length = 1095
Score = 88.6 bits (210), Expect = 2e-16
Identities = 83/305 (27%), Positives = 133/305 (43%), Gaps = 33/305 (10%)
Query: 66 LRLLGWDLKLKE-NKAIRSPYYKECQFFTGRVLHEEGSAVTVTECD--GQLYGLLQVGGE 122
LR L +++E A R E F++GRVL GS V+++ C G L GL+Q+G E
Sbjct: 100 LRFLSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQE 159
Query: 123 EFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHS 182
+ ++QP + R + + S + + + PT
Sbjct: 160 QVLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTW------- 212
Query: 183 DHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIF 242
+++ + R + +E +VAD M+++HG E + +IL +MN+V +F
Sbjct: 213 GRPSRDWRERRNAIRLTSEHT----VETLVVADADMVQYHGAEAAQRFILTVMNMVYNMF 268
Query: 243 NDPSLGSNITLVINKLFLYEDKDIILKYGNI-KKSLEAINKW--------NYRHLMKLPE 293
SLG I + + KL L + L G+ ++SLE+ W Y ++P
Sbjct: 269 QHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPG 328
Query: 294 GSTG---WDATIWLTRSQL----GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIA 343
G DA +++TR+ P G A +GGVC+ R + D GL AF IA
Sbjct: 329 GKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIA 388
Query: 344 HELAH 348
HEL H
Sbjct: 389 HELGH 393
>UniRef50_Q8TE59 Cluster: ADAMTS-19 precursor; n=27; Tetrapoda|Rep:
ADAMTS-19 precursor - Homo sapiens (Human)
Length = 1207
Score = 88.2 bits (209), Expect = 3e-16
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 30/277 (10%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAE 150
F+TG VL GS + + C G L G +Q+ + ++P V +RS E
Sbjct: 221 FYTGAVLRHPGSLASFSTCGGGLMGFIQLNEDFIFIEPLNDTMAITGHPHRVYRQKRSME 280
Query: 151 YNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLEL 210
+T + + P S K Y + + + +E
Sbjct: 281 EKVTEKSALHSHYCGIISDKGRPRSRKIAESG--RGKRYSYKLP---------QEYNIET 329
Query: 211 AIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY 270
+VAD M+ +HG + + +IL ++N+V +F SLG + L + KL L + L
Sbjct: 330 VVVADPAMVSYHGADAARRFILTILNMVFNLFQHKSLGVQVNLRVIKLILLHETPPELYI 389
Query: 271 GNI-KKSLEAINKWNYRHLMKLP----EGSTGW-------DATIWLTRSQL----GGPS- 313
G+ +K LE+ KW + K E ST W DA I +TR P
Sbjct: 390 GHHGEKMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPCD 449
Query: 314 --GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G A + G+C++ R I D GL AF IAHE+ H
Sbjct: 450 TVGIAYLSGMCSEKRKCIIAEDNGLNLAFTIAHEMGH 486
>UniRef50_Q4SQ15 Cluster: Chromosome 7 SCAF14536, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF14536, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 670
Score = 87.0 bits (206), Expect = 6e-16
Identities = 72/267 (26%), Positives = 118/267 (44%), Gaps = 34/267 (12%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT------QEKHVLRRRDVTH 144
F+TG V + E +AV ++ CDG L G++Q+G EEF ++P +E+ RR V +
Sbjct: 53 FYTGEVSNVEDTAVAISNCDG-LAGMIQMGHEEFFIEPLSQRSSAGGEEEEEEGRRHVVY 111
Query: 145 SERSAEYN--LTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASG 202
+ N +V + P + Y + +F
Sbjct: 112 RSTAVIKNPPAVNQSVDDFHRGPLLGSLNLKQEVLLPPSGSARRRRYIEEAEMFN----- 166
Query: 203 VKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE 262
+E+ + D ++ FHGRE ++ Y+L MNIV+ I+ D SLG+NI +V+ K
Sbjct: 167 -----IEVLLAVDYSVHLFHGREHIQRYLLTFMNIVNEIYQDHSLGANINIVLVK----- 216
Query: 263 DKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVC 322
II + ++ A + +L + G +G ++ P +APV G+C
Sbjct: 217 ---IIALPASKREQSHAEQHDHTIYLSRQEFGPSGMQVRCFI-------PISYAPVTGMC 266
Query: 323 TKTRSAAIDRDEGLTSAFVIAHELAHL 349
+S + D TSAFV AHE H+
Sbjct: 267 QLHQSCVLVIDGRFTSAFVAAHETGHV 293
>UniRef50_Q8TE57 Cluster: ADAMTS-16 precursor; n=64;
Euteleostomi|Rep: ADAMTS-16 precursor - Homo sapiens
(Human)
Length = 1224
Score = 87.0 bits (206), Expect = 6e-16
Identities = 51/151 (33%), Positives = 83/151 (54%), Gaps = 15/151 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD-- 265
+E +V D M++ HG E + Y+L ++N+VSA+F D ++G NI + I L L ED+
Sbjct: 292 VETLVVVDKKMMQNHGHENITTYVLTILNMVSALFKDGTIGGNINIAIVGLILLEDEQPG 351
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGS--------TGWDATIWLTRSQLGGPSGFAP 317
+++ + + +L + +W + K +G+ TG D W +++ GFAP
Sbjct: 352 LVISH-HADHTLSSFCQWQSGLMGK--DGTRHDHAILLTGLDICSW--KNEPCDTLGFAP 406
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 407 ISGMCSKYRSCTINEDTGLGLAFTIAHESGH 437
>UniRef50_Q9UHI8 Cluster: ADAMTS-1 precursor; n=31;
Euteleostomi|Rep: ADAMTS-1 precursor - Homo sapiens
(Human)
Length = 967
Score = 85.8 bits (203), Expect = 1e-15
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 259 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 317
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 318 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 377
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 378 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 406
>UniRef50_A2BIA2 Cluster: Novel protein similar to vertebrate ADAM
metallopeptidase with thrombospondin type 1 motif, 8;
n=9; Euteleostomi|Rep: Novel protein similar to
vertebrate ADAM metallopeptidase with thrombospondin
type 1 motif, 8 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 884
Score = 84.6 bits (200), Expect = 3e-15
Identities = 66/269 (24%), Positives = 121/269 (44%), Gaps = 20/269 (7%)
Query: 87 KECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSE 146
++C F+TG V E+ S V V+ C G ++G G E+ + P + + T +
Sbjct: 111 RDC-FYTGTVNSEKESVVAVSLCHG-IHGTFITQGVEYFIHPKASVQ---------TTGK 159
Query: 147 RSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGL 206
+ ++ + + +S ++ +M +R S +
Sbjct: 160 HFPQVHVIKRRAVSNSRTASLVFDQMKVDSLVKESKLNSSEDEDSNMRRAKRFVSAAR-- 217
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +F+G E +KHY+L +M + + +F PSL + ++LV+ K+ + ED+++
Sbjct: 218 YIETLVVADASMTRFYGDE-IKHYLLTVMAMAAQVFVHPSLKNAVSLVVVKMVVVEDEEV 276
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +D I TR + G G A VG
Sbjct: 277 GPELSSNGGVALRNFCMWQQLFNPGSQRHPEHYDTAILFTREDICGYKDCDTLGVADVGT 336
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS ++ D GL +AF ++HEL H+
Sbjct: 337 MCDPKRSCSVIEDNGLQAAFTVSHELGHV 365
>UniRef50_UPI00015B5B5C Cluster: PREDICTED: similar to adamts-7;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
adamts-7 - Nasonia vitripennis
Length = 1215
Score = 82.6 bits (195), Expect = 1e-14
Identities = 54/153 (35%), Positives = 81/153 (52%), Gaps = 14/153 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E +VAD TM+ FH V+ Y+L +MN+VSA++ DPS+G+ I +V+ ++ L E+ D
Sbjct: 284 VEALVVADRTMMAFHQDGDVETYLLTIMNMVSALYLDPSIGNFINVVVVRIILMEEDDAE 343
Query: 268 LKYG---NIKKSLEAINKWNYRHLMKLPEGS--TGWDATIWLTR----SQLGGPS---GF 315
N K+L KW + + P+ S D I +TR S+ P G
Sbjct: 344 PGLNITINADKTLYNFCKWQQK--LNPPDDSHPNHHDVAILVTREDICSRANTPCSTLGV 401
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
A V G+C RS +++ D G+T A I HEL H
Sbjct: 402 AHVAGMCQPDRSCSVNEDNGITLAHTITHELGH 434
>UniRef50_A7RMZ8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 956
Score = 81.8 bits (193), Expect = 2e-14
Identities = 76/293 (25%), Positives = 126/293 (43%), Gaps = 31/293 (10%)
Query: 76 KENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT---- 131
++ + ++ + C F TG+V S V ++ C G L GL+ F ++P
Sbjct: 73 RDGRILKRHTMENCHF-TGKVRSSTRSTVAMSNCQG-LRGLIHTEEGAFFVEPLPAHLHS 130
Query: 132 ------QEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHS 185
+ HV+ RRD+ + R+ T + + P+ + +D S
Sbjct: 131 RGMVSGRNPHVIYRRDLPMNPRNRRVAETKE--LHSCGTEGKTMCHDPSIRLVRALNDSS 188
Query: 186 DKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDP 245
+ D PA ++E +V D M FHG + K Y LA NIVSA F+D
Sbjct: 189 TDD---DRS---GPAGPGAEKYIESLVVVDPKMANFHGEDAAKQYALAACNIVSAKFSDS 242
Query: 246 SLGSN-ITLVINKLFLY--EDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATI 302
SLG N I LV++++ + + +I+ + + +LE+ KW R+ L +D
Sbjct: 243 SLGENPINLVVSRMQILTTQQPGLIINH-HASNTLESFGKWAERNNNPLDNDENHYDYAT 301
Query: 303 WLTR-------SQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
TR +Q G A G+C+ SA++++D GL +AHE H
Sbjct: 302 LFTRYNICKDKNQPCDTLGLARTRGMCSFPSSASVNQDNGLMLGMTLAHETGH 354
>UniRef50_Q3ULV2 Cluster: Mammary gland RCB-0527 Jyg-MC(B) cDNA,
RIKEN full-length enriched library, clone:G930037F13
product:a disintegrin-like and metalloprotease
(reprolysin type) with thrombospondin type 1 motif, 20,
full insert sequence; n=2; Murinae|Rep: Mammary gland
RCB-0527 Jyg-MC(B) cDNA, RIKEN full-length enriched
library, clone:G930037F13 product:a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin
type 1 motif, 20, full insert sequence - Mus musculus
(Mouse)
Length = 509
Score = 81.4 bits (192), Expect = 3e-14
Identities = 48/151 (31%), Positives = 82/151 (54%), Gaps = 10/151 (6%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY--EDK 264
++E+ + AD M+ HG + ++HY+L LM+IV+AI+ D S+G+ I +VI KL + E +
Sbjct: 256 YVEVMVTADAKMVHHHG-QNLQHYVLTLMSIVAAIYKDSSIGNLINIVIVKLVVIHSEQE 314
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPV 318
++ + N +L W + + D + +TR + G G A +
Sbjct: 315 GPVISF-NAATTLRNFCLWQQSQNVLDDAHPSHHDTAVLITREDICGAKEKCDTLGLAEL 373
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G +C +RS +I + GL++AF IAHEL H+
Sbjct: 374 GTLCDPSRSCSISEENGLSAAFTIAHELGHV 404
>UniRef50_UPI0000DB7178 Cluster: PREDICTED: similar to CG4096-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4096-PA
- Apis mellifera
Length = 1195
Score = 81.0 bits (191), Expect = 4e-14
Identities = 50/149 (33%), Positives = 78/149 (52%), Gaps = 8/149 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E +VAD TM+ FH V+ Y+L +MN+VS+++ DP++G+ I +V+ ++ L E+ D
Sbjct: 279 VEALVVADTTMMAFHQDGDVETYLLTIMNMVSSLYLDPTIGNFINVVVVRIILVEEDDQG 338
Query: 268 LKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTR----SQLGGPS---GFAPVG 319
L N ++L KW + D I +TR S+ P G A V
Sbjct: 339 LDITVNADRTLYNFCKWQQKLNPADDSHPNHHDVAILVTREDICSRANTPCSTLGVAHVA 398
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G+C RS +++ D G+T A I HEL H
Sbjct: 399 GMCQPDRSCSVNEDNGITLAHTITHELGH 427
>UniRef50_Q9W493 Cluster: CG4096-PA; n=3; Sophophora|Rep: CG4096-PA
- Drosophila melanogaster (Fruit fly)
Length = 1059
Score = 80.2 bits (189), Expect = 7e-14
Identities = 45/148 (30%), Positives = 80/148 (54%), Gaps = 9/148 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E IVAD TM FH + Y+L +MN+VSA++ DPS+G++I +V+ ++ ++++
Sbjct: 332 VETLIVADATMSAFH--RDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQ 389
Query: 268 LKYG---NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGG 320
L+ N +K+L+ W ++ + D I +TR + + G A VGG
Sbjct: 390 LQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGG 449
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+C +S +++ D G+ + I HEL H
Sbjct: 450 MCKPKQSCSVNEDNGIMLSHTITHELGH 477
>UniRef50_A7SUT8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 834
Score = 80.2 bits (189), Expect = 7e-14
Identities = 49/152 (32%), Positives = 82/152 (53%), Gaps = 15/152 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE----D 263
+E+ +VAD TM +FHG ++ Y+L +MN+V+ I+ D S+G+ I +V+ ++ + + D
Sbjct: 85 VEVLVVADRTMHEFHGAA-LEEYLLTVMNMVNNIYRDQSIGNAINIVVVRIIILKRDLPD 143
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG-------GPSGFA 316
DI GN ++E+ W R + D + +TR + G G A
Sbjct: 144 LDIGHHAGN---TIESFCAWASRVNPRSDTHPNHHDVAVLVTRKDICKGIDEPCGTLGLA 200
Query: 317 PVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V G+CT T+S ++ D GL+ A+ IAHE+ H
Sbjct: 201 QVNGMCTSTKSCNVNEDSGLSVAYTIAHEIGH 232
>UniRef50_UPI0000E4A7C7 Cluster: PREDICTED: similar to ADAMTS6
variant 2, partial; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to ADAMTS6 variant 2,
partial - Strongylocentrotus purpuratus
Length = 1320
Score = 79.0 bits (186), Expect = 2e-13
Identities = 49/158 (31%), Positives = 81/158 (51%), Gaps = 17/158 (10%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E +VAD M+ +HG ++ Y+L LMNIV+ +++D S+ + I +V+ ++ L
Sbjct: 370 VETLVVADKMMMGYHGETSIESYLLTLMNIVANLYHDGSIENAINVVVTRMLLLTQDQRN 429
Query: 268 LKYGNIK-KSLEAINKWNY------RHLMKLPEGS---TGWDATIWLTR-------SQLG 310
L ++ KSL++ +W + H M + D + +TR +Q
Sbjct: 430 LSLSHLAGKSLQSFCEWQHAMNPAPNHNMNISNDMLVFPNHDNAVLITRYDLCMRFNQPC 489
Query: 311 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G G APVG +C +S I+ D GL +AF IAHE+ H
Sbjct: 490 GTIGLAPVGVMCRPDQSCNINEDTGLATAFTIAHEIGH 527
>UniRef50_UPI0000E482BE Cluster: PREDICTED: similar to ADAMTS-9
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9); n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
ADAMTS-9 precursor (A disintegrin and metalloproteinase
with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) -
Strongylocentrotus purpuratus
Length = 1693
Score = 78.6 bits (185), Expect = 2e-13
Identities = 49/150 (32%), Positives = 80/150 (53%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED-KD 265
+LE+ +VAD+ M++ HG V+ Y+L L+ +V+ IF DPS+G+ I + + +L + ++ D
Sbjct: 120 YLEMMVVADHKMVEHHGGG-VQLYVLTLVAVVNRIFRDPSIGNAINVTLVELRILQNVND 178
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL--GGPS----GFAPVG 319
N +L+ W + +D + LTR + GP G A +G
Sbjct: 179 GPHISSNAPMTLKNFCAWQQQQNQAEDSHPHHYDTAVLLTREDICRSGPDCDTLGLAELG 238
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC RS +I D GL++AF +AHEL H+
Sbjct: 239 TVCDPLRSCSIVEDNGLSAAFTMAHELGHV 268
>UniRef50_Q179V7 Cluster: Adamts-7; n=3; Endopterygota|Rep: Adamts-7
- Aedes aegypti (Yellowfever mosquito)
Length = 1037
Score = 78.6 bits (185), Expect = 2e-13
Identities = 44/149 (29%), Positives = 81/149 (54%), Gaps = 8/149 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E +VAD++M +FH ++ Y+L +MN+VS+++ DP++G++I + + ++ + E+++
Sbjct: 309 VEALVVADHSMAQFHQDADLQQYLLTIMNMVSSLYRDPTIGNSIQVTVVRIIILEEEESH 368
Query: 268 LKYG---NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---GGPS--GFAPVG 319
+ +LE +W K D I +TR + G S G A VG
Sbjct: 369 ADFNVTHIAANTLENFCRWQRSLNPKDENDPHHHDVAILVTRKNICSTHGCSTLGVANVG 428
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G+C +S +++ D G+T A I+HEL H
Sbjct: 429 GMCRPDKSCSVNEDNGITLAHTISHELGH 457
>UniRef50_UPI00004D24D1 Cluster: ADAMTS-18 precursor (EC 3.4.24.-)
(A disintegrin and metalloproteinase with thrombospondin
motifs 18) (ADAM-TS 18) (ADAM-TS18).; n=2; Xenopus
tropicalis|Rep: ADAMTS-18 precursor (EC 3.4.24.-) (A
disintegrin and metalloproteinase with thrombospondin
motifs 18) (ADAM-TS 18) (ADAM-TS18). - Xenopus
tropicalis
Length = 812
Score = 77.8 bits (183), Expect = 4e-13
Identities = 78/278 (28%), Positives = 116/278 (41%), Gaps = 23/278 (8%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPT--RTQEKHVLRRRDVTHS--- 145
F+ G + E S V V+ CDG + G L+ EF + P EKH D H
Sbjct: 88 FYQGFIRDYENSTVAVSTCDG-MSGFLRTHTSEFFISPLPQHLAEKHNYTSPDGHHPHVL 146
Query: 146 -ERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVK 204
+RSAE T T S + + ++ +R A+ +
Sbjct: 147 YKRSAEAKQTLHTFAHLSWPYIPRFGLASLDIYAHMVSFMVKADEYENLSRAKRSATKSQ 206
Query: 205 ---GLWLELAIVADNTMLKFHGRERVKHYILALMNIVSA----IFNDPSLGSNITLVI-N 256
GL +E +VAD M+ HG++ V YIL +MN+VS F DP+ I+ +
Sbjct: 207 HSGGLVVETLVVADKKMVDKHGKDSVTTYILTVMNMVSLSQPHCFTDPTSQRYISYICCQ 266
Query: 257 KLFLYEDKDIILKYGNIKKSLEAINKWNY----RHLMKLPEGS--TGWDATIWLTRSQLG 310
+F + + +SL +W +H + TG D W +++
Sbjct: 267 PVFFSPPQAGFTINHHADQSLNNFCQWQSALTGKHGKRHDHAILLTGLDICSW--KNEPC 324
Query: 311 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GFAP+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 325 DTLGFAPINGMCSKYRSCTINEDTGLGLAFTIAHESGH 362
>UniRef50_UPI0000E46B78 Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 3
proprotein; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to ADAM metallopeptidase with
thrombospondin type 1 motif, 3 proprotein -
Strongylocentrotus purpuratus
Length = 875
Score = 77.4 bits (182), Expect = 5e-13
Identities = 49/157 (31%), Positives = 84/157 (53%), Gaps = 5/157 (3%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
R P + ++E D ++ FHG + Y L +MNIV+ ++ PSL + I VI
Sbjct: 110 RAPRIVTRQHYVETMATLDFSVHNFHGAQASGVYFLTMMNIVNMVYAHPSLEAKIEFVIT 169
Query: 257 KLFLYEDK--DIILKYGNIKKSLEAINKWN--YRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+ L ++ + + + KSL ++ R ++K + +D +I++TR+ G P
Sbjct: 170 RANLLNEEMSEQYVVLNDSAKSLSNTCRFARVQRRIVKDDGSPSYFDHSIFMTRTHFG-P 228
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+G AP+G +C S ++ D+GL SAFV+AHEL H+
Sbjct: 229 AGIAPLGLMCWIYFSCSLTEDDGLGSAFVLAHELGHV 265
>UniRef50_UPI00015A8026 Cluster: UPI00015A8026 related cluster; n=5;
Danio rerio|Rep: UPI00015A8026 UniRef100 entry - Danio
rerio
Length = 1504
Score = 77.4 bits (182), Expect = 5e-13
Identities = 49/158 (31%), Positives = 79/158 (50%), Gaps = 8/158 (5%)
Query: 199 PASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKL 258
P S + W+E +V D+ ++ +HG V+ YI +MN+V+ IF+D S+G+ I +V+ +L
Sbjct: 258 PRSISRERWVETMVVGDSKLVDYHGSGSVESYIFTIMNMVAGIFHDASIGNAIHIVLVRL 317
Query: 259 FLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL-GGPS--- 313
L ++ LK + +L + W + D I +TR + G +
Sbjct: 318 ILLHGEEKGLKIIHHADTTLTSFCTWQKNLNPQSDTHPAHHDVAILITRKDVCAGMNQPC 377
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + + G+C RS I+ D GL AF IAHEL H
Sbjct: 378 ETLGLSHLSGMCQPHRSCNINEDSGLPVAFTIAHELGH 415
>UniRef50_A7S1V9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 502
Score = 76.6 bits (180), Expect = 9e-13
Identities = 46/142 (32%), Positives = 75/142 (52%), Gaps = 11/142 (7%)
Query: 218 MLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VINKLFLYEDKDIILKYGNIKKS 276
M+ FHG + ++ Y+L +MN+VS+++ DPSLG++I + V+ ++L+ + + N +K+
Sbjct: 1 MVGFHGNDSIEEYVLTVMNMVSSMYRDPSLGTSIKIEVLKIIYLHATPEGLRITPNGRKT 60
Query: 277 LEAINKW-NYRHLMKLPEGSTGW--DATIWLTRSQL----GGPSGFAPVG---GVCTKTR 326
L + W N M W DA + +TR + P +G G+C R
Sbjct: 61 LRSFCDWQNSLQWMTGYSAKHHWDYDAAVLMTRKDICADQNEPCSTVGIGYMYGMCDTKR 120
Query: 327 SAAIDRDEGLTSAFVIAHELAH 348
++ D GL AF IAHELAH
Sbjct: 121 RCSVSEDSGLNVAFTIAHELAH 142
>UniRef50_UPI00015B5FBF Cluster: PREDICTED: similar to a
disintegrin-like and metalloprotease with thrombospondin
type 1 motifs 9B; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 9B -
Nasonia vitripennis
Length = 1733
Score = 76.2 bits (179), Expect = 1e-12
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 12/154 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E+ +VAD M+ +HG + +YIL LMN VS I+ DPS+G+ I++ + K+ +
Sbjct: 364 FIEVMVVADAKMIDYHGAS-LTYYILVLMNTVSRIYKDPSIGNPISIAVIKIKQVDQIFG 422
Query: 267 ILKYGNIK-KSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQL-GGPS-------GF 315
+ + G+ + E + K+ Y + P + DA + LTR L P G
Sbjct: 423 VKQEGSDGIGAAEMLRKFCYWQTLNNPHEPSPEHHDAALLLTRENLCHNPGEKRCDTLGL 482
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
A +G +C+ S AI +D GL +AF IAHE+ H+
Sbjct: 483 AELGRMCSPGSSCAIVQDNGLATAFTIAHEIGHV 516
>UniRef50_A7RW19 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1592
Score = 76.2 bits (179), Expect = 1e-12
Identities = 47/151 (31%), Positives = 80/151 (52%), Gaps = 8/151 (5%)
Query: 207 WLELAIVADNTMLK-FHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE-DK 264
++E + AD +M+ F + ++ +I+ +M +V+ I+ D ++G++I +V+ K+ + E D
Sbjct: 10 YVETMVTADKSMVDAFPSKAELQSFIITIMGMVARIYRDKTIGNSINIVLVKIIILEIDL 69
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPV 318
+ N SL + KW + E +D I LTR + +G A +
Sbjct: 70 PELEITSNAASSLRSFCKWQTKMNKPSDEEPGHFDTAILLTRKDICRAAGKCDTLGLAEL 129
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC +RS +I GL+SAF IAHELAH+
Sbjct: 130 GTVCNPSRSCSIVEVTGLSSAFTIAHELAHV 160
>UniRef50_O75173 Cluster: ADAMTS-4 precursor; n=26; Tetrapoda|Rep:
ADAMTS-4 precursor - Homo sapiens (Human)
Length = 837
Score = 76.2 bits (179), Expect = 1e-12
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 335
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 336 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>UniRef50_Q4RSP7 Cluster: Chromosome 12 SCAF14999, whole genome
shotgun sequence; n=5; Eukaryota|Rep: Chromosome 12
SCAF14999, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1673
Score = 74.1 bits (174), Expect = 5e-12
Identities = 47/167 (28%), Positives = 82/167 (49%), Gaps = 15/167 (8%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
R S K W+E +VAD+ ++++HG + V+ YI +MN+V+ IF+D S+G+ I +++
Sbjct: 249 RTQRSVSKERWVETMVVADSKLIEYHGSDNVESYIFTIMNMVAGIFHDASIGNAIHVILV 308
Query: 257 KLFLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTR--------- 306
+L L ++ LK + +L + W + D + +TR
Sbjct: 309 RLILLHGEEKGLKIVHHADTTLSSFCTWQKNLNPQSDTHPAHHDVAVLITRRVARSRPKD 368
Query: 307 --SQLGGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ + P G + + G+C RS I+ D GL AF +AHE+ H
Sbjct: 369 ICAGMNQPCETLGLSHLSGMCQPHRSCNINEDSGLPVAFTVAHEMGH 415
>UniRef50_Q19791 Cluster: ADAMTS family gon-1 precursor; n=3;
cellular organisms|Rep: ADAMTS family gon-1 precursor -
Caenorhabditis elegans
Length = 2165
Score = 72.9 bits (171), Expect = 1e-11
Identities = 45/150 (30%), Positives = 80/150 (53%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E+ +VAD M ++HGR ++ Y+L L + V++I+ SL ++I +V+ KL + + ++
Sbjct: 281 YVEVLVVADTKMYEYHGRS-LEDYVLTLFSTVASIYRHQSLRASINVVVVKLIVLKTENA 339
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVG 319
+ N +++L+ +W + D I LTR + G A +G
Sbjct: 340 GPRITQNAQQTLQDFCRWQQYYNDPDDSSVQHHDVAILLTRKDICRSQGKCDTLGLAELG 399
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S AI D GL++AF IAHEL H+
Sbjct: 400 TMCDMQKSCAIIEDNGLSAAFTIAHELGHV 429
>UniRef50_UPI0000D5652D Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 9
preproprotein; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to ADAM metallopeptidase with thrombospondin
type 1 motif, 9 preproprotein - Tribolium castaneum
Length = 1716
Score = 72.5 bits (170), Expect = 1e-11
Identities = 43/146 (29%), Positives = 78/146 (53%), Gaps = 5/146 (3%)
Query: 207 WLELAIVADNTMLKFH-GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD 265
++++ +VAD +M+++H E +KHYIL LM+ + ++ D S+G++I+L + ++L +
Sbjct: 303 FVKVLVVADRSMIQYHQSNEDLKHYILILMSHAALLYKDASIGNSISLSVVNIWLLNNT- 361
Query: 266 IILKYGNIKKSLEAINKWNYRHLM--KLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ N + L +W R++ K I S G A VG +C
Sbjct: 362 -VFTSNNSQVMLRRFCEWQKRYVTDRKHDMALLFTRDPICKKNSSSCDTLGVAEVGSMCN 420
Query: 324 KTRSAAIDRDEGLTSAFVIAHELAHL 349
+ S AI ++ GL+S++ IAHEL H+
Sbjct: 421 PSSSCAIVKERGLSSSYTIAHELGHV 446
>UniRef50_Q9UP79 Cluster: ADAMTS-8 precursor; n=24; Amniota|Rep:
ADAMTS-8 precursor - Homo sapiens (Human)
Length = 890
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M F+G + ++++IL LM++ + I+ PS+ ++I L++ K+ + ED+
Sbjct: 221 FVETLLVADASMAAFYGAD-LQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKW 279
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF------APVG 319
+ N +L W R +D I LTR G G A +G
Sbjct: 280 GPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIG 339
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ DEGL +A +AHEL H+
Sbjct: 340 TICDPNKSCSVIEDEGLQAAHTLAHELGHV 369
>UniRef50_UPI00015B5B5B Cluster: PREDICTED: similar to adamts-7;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
adamts-7 - Nasonia vitripennis
Length = 1782
Score = 72.1 bits (169), Expect = 2e-11
Identities = 46/151 (30%), Positives = 80/151 (52%), Gaps = 9/151 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNI-TLVINKLFLYEDK- 264
++E+A+VAD L FH + Y+L +MN+VS ++D S+G+ I +V+ ++L ++K
Sbjct: 254 YIEVALVADRRFLDFHKGTNYEQYLLTVMNMVSDYYHDASVGNQIDVIVVRIVYLEKEKN 313
Query: 265 DIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAP 317
+I L+ + +K+LE+ KW + + +D +TR + G A
Sbjct: 314 EIDLQISPDAEKTLESFAKWIEKLNPTDTQHPNHFDIGALVTRHDICAEGNNCNLLGLAF 373
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V C + ++A I+ D GL VIAHE+ H
Sbjct: 374 VAAACERKKAACINEDSGLLLGIVIAHEIGH 404
>UniRef50_Q4RY30 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 3
SCAF14978, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 981
Score = 71.7 bits (168), Expect = 3e-11
Identities = 52/159 (32%), Positives = 78/159 (49%), Gaps = 11/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD TM K +G++ + HY+L L +I S ++ S+ + I L +
Sbjct: 242 RRKRSVSRARHVELLLVADETMTKKYGKD-LNHYLLTLASIASRLYGHASIENPIRLSVV 300
Query: 257 KLFLYEDK----DIILKYGNIKKSLEAINK--WNYRHLMKLPEGSTGWDATIWLTRSQLG 310
K+ D D+ KS A + +YR +L G G D L
Sbjct: 301 KVTAVSDGEKGLDVSKNAAATLKSFCATGRRAGDYRIFWRLQFGRMGRD----LCGHHSC 356
Query: 311 GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C+ RS A+ D+GL +AF +AHE+ HL
Sbjct: 357 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHL 395
>UniRef50_Q8SXB0 Cluster: GH16393p; n=3; Sophophora|Rep: GH16393p -
Drosophila melanogaster (Fruit fly)
Length = 1688
Score = 71.7 bits (168), Expect = 3e-11
Identities = 79/297 (26%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 65 HLRLL--GWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGE 122
H+R+L G + E +A + C F++G V + S V+V+ C G + G ++
Sbjct: 323 HIRILKEGEEHPGPETEAEAEQRHLGC-FYSGYVEDDPHSMVSVSLCGG-MTGYIKTSFG 380
Query: 123 EFVLQPT-RTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRH 181
++QP RT VL R S+R+A + ++ + R
Sbjct: 381 ALLIQPVNRTSSDEVLHRV-FRKSQRNARHAVSKFELGLDDFMSKLEQVQEEEQKSKSRK 439
Query: 182 SDHSDKEYFH-DMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSA 240
+ + Y D ++ LE+ I DN+M +FHG E ++ YIL LM+IVS+
Sbjct: 440 LNRKKRHYADVDNQVYT----------LEVLIAVDNSMKQFHG-EDLQPYILILMSIVSS 488
Query: 241 IFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDA 300
IF D S+G++I +++ +L + NI + N+ + + D
Sbjct: 489 IFADASIGNSIRILLVRL---------ISLPNINDQTHSSNEMLKHFCQFINQSGYERDT 539
Query: 301 TIWLTRSQLGG--PS------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ +TR + G P G A +G VC+ + S +I +D GL +AF +AHEL H+
Sbjct: 540 AMLITREPICGSVPGKICHMLGLAELGTVCSSS-SCSIVQDTGLPTAFTMAHELGHI 595
>UniRef50_UPI0000DB737E Cluster: PREDICTED: similar to ADAMTS-9
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9); n=2;
Apis mellifera|Rep: PREDICTED: similar to ADAMTS-9
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9) - Apis
mellifera
Length = 1763
Score = 70.5 bits (165), Expect = 6e-11
Identities = 53/176 (30%), Positives = 90/176 (51%), Gaps = 13/176 (7%)
Query: 186 DKEYFHDMHLFRRPASGVKG-LWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFND 244
D E D + RP + ++E+ + AD M+++HG+ + YIL LM+ VS I+ D
Sbjct: 229 DSEMESDPSVTWRPRRALSSEYFIEIMVAADAEMVRYHGKGLLG-YILGLMSTVSRIYKD 287
Query: 245 PSLGSNITLVINKLFLYEDKDIILKY-GNIKKSLEAINKW-NYRHLMKLPEGSTG-WDAT 301
PS+G+ I++ + + + + + G + + +NK+ ++ E S G +D
Sbjct: 288 PSIGNPISISVMSIVPIDKIFGVRRTKGEGIAAADMLNKFCRWQQSNNPNEYSPGHYDTA 347
Query: 302 IWLTRSQLGGPS--------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ LTR L S G A +G +C+ S AI +D GL +AF IAHE+ H+
Sbjct: 348 LLLTRENLCHNSDQRNCDTLGLAELGRMCSPRSSCAIVQDNGLAAAFTIAHEIGHV 403
>UniRef50_Q1RLB3 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 1820
Score = 69.3 bits (162), Expect = 1e-10
Identities = 42/148 (28%), Positives = 75/148 (50%), Gaps = 9/148 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E+ + ADN ML+ H + V+HY+L LM IV+ ++ DPS+ + + +V+ KL + D
Sbjct: 337 VEVMVTADNAMLRSH--DDVEHYVLTLMAIVNHVYRDPSIENLVNIVLVKLIVIGDSQNG 394
Query: 268 LKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVGG 320
+ + L +W + D ++ +T + + G A +G
Sbjct: 395 PRVARDAHTCLRNFCEWQFTQNDPDDSHPDHHDTSVLITGQDICRSNSVCDTLGLAELGT 454
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+C +S +I+ D GL++AF IAHE+ H
Sbjct: 455 MCDLRKSCSINEDNGLSTAFTIAHEIGH 482
>UniRef50_Q59FE5 Cluster: A disintegrin-like and metalloprotease
(Reprolysin type) with thrombospondin type 1 motif, 10
preproprotein variant; n=4; Euteleostomi|Rep: A
disintegrin-like and metalloprotease (Reprolysin type)
with thrombospondin type 1 motif, 10 preproprotein
variant - Homo sapiens (Human)
Length = 847
Score = 69.3 bits (162), Expect = 1e-10
Identities = 44/126 (34%), Positives = 68/126 (53%), Gaps = 15/126 (11%)
Query: 238 VSAIFNDPSLGSNITLVINKLFLY-EDKDIILKYGNIKKSLEAINKW-----NYR-HLMK 290
V+ +F D SLGS + +++ +L L ED+ + + KSL++ KW N+ H
Sbjct: 25 VAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNA 84
Query: 291 LPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVI 342
+PE G D + +TR + G G APVGG+C + RS +++ D GL +AF I
Sbjct: 85 IPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTI 144
Query: 343 AHELAH 348
AHE+ H
Sbjct: 145 AHEIGH 150
>UniRef50_UPI0000DA2EEE Cluster: PREDICTED: similar to ADAMTS-8
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 8) (ADAM-TS 8) (ADAM-TS8)
(METH-2); n=1; Rattus norvegicus|Rep: PREDICTED: similar
to ADAMTS-8 precursor (A disintegrin and
metalloproteinase with thrombospondin motifs 8) (ADAM-TS
8) (ADAM-TS8) (METH-2) - Rattus norvegicus
Length = 905
Score = 68.9 bits (161), Expect = 2e-10
Identities = 42/150 (28%), Positives = 78/150 (52%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E+ +VAD +M F+G + ++++IL +M++ + I+ PS+ ++I LV+ K+ + E++
Sbjct: 235 FVEILLVADASMAAFYGTD-LQNHILTVMSMAARIYKHPSIRNSINLVVVKVLIVEEEGW 293
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
+ N +L W R +D I TR G A VG
Sbjct: 294 GPEVSDNGGLTLRNFCSWQRRFNKPSDRHPEHYDTAILFTRQNFCRKGEQCDTLGMADVG 353
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ +DEGL +A+ +AHEL H+
Sbjct: 354 TICDPNKSCSVIKDEGLQAAYTLAHELGHV 383
>UniRef50_Q4RYQ0 Cluster: Chromosome 16 SCAF14974, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
SCAF14974, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 901
Score = 68.9 bits (161), Expect = 2e-10
Identities = 42/146 (28%), Positives = 71/146 (48%), Gaps = 7/146 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M F+G E ++HY+L L++ + ++ PS+ + ++LV+ K+ + ED +
Sbjct: 190 FIETLVVADASMAYFYGDE-IQHYVLTLVSTAAQLYRHPSIKNRVSLVLVKMLVVEDAEA 248
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +D + TR + G G A VG
Sbjct: 249 GPRLSANGGVALRNFCSWQQLFNPPSQRHPEHYDTAVLFTREDICGQKSCDTLGVADVGT 308
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHEL 346
+C RS ++ D GL AF AHEL
Sbjct: 309 MCDPKRSCSVIEDNGLQDAFTAAHEL 334
>UniRef50_Q7QB38 Cluster: ENSANGP00000012879; n=2; Culicidae|Rep:
ENSANGP00000012879 - Anopheles gambiae str. PEST
Length = 1325
Score = 68.1 bits (159), Expect = 3e-10
Identities = 53/178 (29%), Positives = 88/178 (49%), Gaps = 20/178 (11%)
Query: 182 SDHSDKEYFHDMHLFRRPASGVKG--LWLELAIVADNTMLKFHGRERVKHYILALMNIVS 239
S+ +D YF RR +E+ +V DN M ++H +K Y+L LM+IVS
Sbjct: 59 SEPTDNNYFSRHSRRRRSPEHFANNDYTVEVLVVVDNQMQRYH-ETNLKTYVLTLMSIVS 117
Query: 240 AIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWD 299
+++ D S+GS++ + + + Y D+ + KK LE ++ + D
Sbjct: 118 SVYADASIGSSMKIAVTHI-SYIHHDLDAQTTAAKKGLEDFCRFK-------QSTNIHHD 169
Query: 300 ATIWLTRSQL-GGPS-------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ LTR Q+ P+ G A +G +C T + AI +D GL+++F IAHEL H+
Sbjct: 170 VALLLTREQICRNPAENNCDTLGLAELGTICRDT-ACAIVQDNGLSASFTIAHELGHV 226
>UniRef50_A7SQN1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 800
Score = 67.7 bits (158), Expect = 4e-10
Identities = 45/151 (29%), Positives = 80/151 (52%), Gaps = 13/151 (8%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE----D 263
+E+ + D + F+G + + +Y+L + N+V ++ D S+G + + + K+FL E +
Sbjct: 225 IEVMMTLDKPSVDFYGNQSM-NYVLGVANMVHRLYRDKSIGFDCSFTLTKVFLIESYLAE 283
Query: 264 KDIIL-KYGNIKKSLEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLGGPS----GFAP 317
DI L + G+ K L +KW + P GS +D + LTR G S G A
Sbjct: 284 LDINLNEIGSASKYLSVFSKWF--QTVNTPAGSVEHFDNAVMLTRDICGTNSCQLDGLAY 341
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G C+ + A+++ G+++AF +AHE+AH
Sbjct: 342 FGYPCSTSLGASVNDAHGVSAAFSVAHEVAH 372
>UniRef50_UPI0000F1ED1E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 355
Score = 66.1 bits (154), Expect = 1e-09
Identities = 45/149 (30%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VINKLFLYEDKD 265
+LELA+V + + H R+ + YIL +NI S + D +LG+NI + ++ + L E +
Sbjct: 62 YLELAVVVGPDVYEVH-RQDTERYILTNLNIASELLRDVTLGANIRVHLVRMIILTEPEP 120
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPV------G 319
I NI SL+++ +W + D +++TR L P+G V G
Sbjct: 121 DIQISENITSSLKSVCEWGQKVNPDADSDPLHADLLLYITRFDLVLPNGNKLVRGVTQFG 180
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GVC+ + I D G IAHE+ H
Sbjct: 181 GVCSTQWNCVITEDTGFDLGITIAHEIGH 209
>UniRef50_UPI0000DB717B Cluster: PREDICTED: similar to ADAMTS-7
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7); n=1;
Apis mellifera|Rep: PREDICTED: similar to ADAMTS-7
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7) - Apis
mellifera
Length = 486
Score = 65.7 bits (153), Expect = 2e-09
Identities = 46/159 (28%), Positives = 76/159 (47%), Gaps = 9/159 (5%)
Query: 199 PASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKL 258
P + +EL +V D T+L +H V++Y L L+N+ +A+ +D SLG N+ L I ++
Sbjct: 18 PKNQANSYTMELLLVLDKTVLDYHKDFDVENYALTLLNMAAALLHDVSLGINMELTIVRI 77
Query: 259 --FLYEDKDIILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL-GGPS- 313
L ++ ++ L + +L+ KW D I +T+S + PS
Sbjct: 78 IRMLVQENEMSLTITKDTNATLKYFQKWQRMINPGDDTHPNHHDCAILITKSNICDSPSV 137
Query: 314 ----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + + G C + AAI D GL + + IAH L H
Sbjct: 138 CGFTGTSTIAGTCDPLKGAAIINDVGLHTGYHIAHHLGH 176
>UniRef50_UPI0000DB7179 Cluster: PREDICTED: similar to ADAMTS-12
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12); n=2;
Apis mellifera|Rep: PREDICTED: similar to ADAMTS-12
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12) -
Apis mellifera
Length = 1076
Score = 65.3 bits (152), Expect = 2e-09
Identities = 42/153 (27%), Positives = 78/153 (50%), Gaps = 10/153 (6%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDK- 264
++E+A+VAD L F+ + Y+L +MNI + ++D S+G+ I LVI ++L ++K
Sbjct: 241 YMEIAVVADRKFLDFYNSSNFEQYLLTIMNIAADYYHDKSVGNQIDLVIVRMIYLEKEKE 300
Query: 265 DIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFA 316
+I L N + +L + W + + + +D + +TR + + G A
Sbjct: 301 EIDLSISPNAEDTLASFAAWADKLNPEDTDHPNHFDIGVLVTRYDICSDNLTNCDLLGLA 360
Query: 317 PVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ C + ++AAI D GL +AHE+ H+
Sbjct: 361 YLATACDRKKAAAICEDTGLNLGITVAHEVGHV 393
>UniRef50_Q4RSH9 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1322
Score = 64.1 bits (149), Expect = 5e-09
Identities = 38/143 (26%), Positives = 75/143 (52%), Gaps = 8/143 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF-LYEDKD 265
++EL + AD M + HG ++HYIL +M++V+A++ DPS+G+ I ++I KL ++ +++
Sbjct: 11 YVELMVTADAKMARHHG-PNLEHYILTIMSVVAAVYRDPSVGNLINIMIVKLIVVHNEQE 69
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N +L W ++ + D + +TR + G A +G
Sbjct: 70 GPTVSFNAATTLHNFCVWQQGQNVQDDSHPSHHDTALLITREDICRAKDKCDTLGLAELG 129
Query: 320 GVCTKTRSAAIDRDEGLTSAFVI 342
+C + RS +I + G++++F I
Sbjct: 130 TMCDQYRSCSISEENGISASFTI 152
>UniRef50_UPI000065CF0E Cluster: Homolog of Homo sapiens "ADAMTS-15
precursor; n=2; Takifugu rubripes|Rep: Homolog of Homo
sapiens "ADAMTS-15 precursor - Takifugu rubripes
Length = 928
Score = 62.9 bits (146), Expect = 1e-08
Identities = 53/225 (23%), Positives = 96/225 (42%), Gaps = 16/225 (7%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTR-----TQEKHVLRRRDVTHS 145
F++G V + S ++ C G L G G E+ + P + T+ H++RRR
Sbjct: 50 FYSGYVNSDRDSYAALSLCKG-LQGAFGSQGWEYFISPVQNNTRSTESAHIIRRRT---- 104
Query: 146 ERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKG 205
S L T + H + + + +R AS +
Sbjct: 105 --SDNLKLNSTTRCAVDSDISLQAAKSLEKYKHLDDYGNVTETMLRRIRRAKRFASVPR- 161
Query: 206 LWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD 265
++E +VADN+M++FHG + +KHY+L LM++ + ++ PS+ + I + + K+ + +++
Sbjct: 162 -YVETLVVADNSMVQFHGDD-LKHYLLTLMSVAARLYKHPSILNFINVAVVKIVILSEEE 219
Query: 266 IILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL 309
K GN +L W + + WD I TR L
Sbjct: 220 KGPKVSGNAAMTLRNFCTWQKKLNKNTDKHPEYWDTAILFTRQVL 264
Score = 41.9 bits (94), Expect = 0.024
Identities = 18/36 (50%), Positives = 23/36 (63%)
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C RS ++ D+GL SAF AHEL H+
Sbjct: 306 GMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHV 341
>UniRef50_Q7Q7Y1 Cluster: ENSANGP00000002429; n=2; Culicidae|Rep:
ENSANGP00000002429 - Anopheles gambiae str. PEST
Length = 889
Score = 62.9 bits (146), Expect = 1e-08
Identities = 59/258 (22%), Positives = 105/258 (40%), Gaps = 24/258 (9%)
Query: 109 CDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXX 168
C+G + GL++ E V+ P E+ + + ++ + +G+T +
Sbjct: 52 CEGSVRGLIRTNESEIVIHPL--PERFGTGAHVILNRNKTIPSDESGETKVMFEPDMNEP 109
Query: 169 XXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVK 228
PT + + K + H + P L +E AI D + + + K
Sbjct: 110 TRRRPTVPFYGQSQQSRLKRHISSNHNAKVPDE----LHIETAIFIDKDLYRHMSKNYPK 165
Query: 229 H-------YILALMNIVSAIFNDPSLGSNITLVINKL-FLYEDKDIILKYGNIKKSLEAI 280
+ ++LA++N V ++N PSLG I ++ +L L+ D + + +I L +
Sbjct: 166 NTEAHLIRFVLAMINGVQLLYNHPSLGHPINFILKRLEILHNDPKDLRRSSDIDIYLNSF 225
Query: 281 NKWNYRHLMKLPEGSTGWDATIWLTRSQL------GGPS----GFAPVGGVCTKTRSAAI 330
W + +D + LT L G S G APV G+CT T S I
Sbjct: 226 CGWQRKMNPISDADPVHFDHAVILTGLDLFVVSKNGKVSNQVVGLAPVAGMCTITSSCTI 285
Query: 331 DRDEGLTSAFVIAHELAH 348
+ + S FV++HE+ H
Sbjct: 286 NEGKHFESVFVVSHEIGH 303
>UniRef50_UPI0000586079 Cluster: PREDICTED: similar to ADAMTS-1
protein, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to ADAMTS-1 protein,
partial - Strongylocentrotus purpuratus
Length = 734
Score = 62.5 bits (145), Expect = 2e-08
Identities = 40/154 (25%), Positives = 74/154 (48%), Gaps = 13/154 (8%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E+ IV+D+TM ++HG E +++Y+ +M+I + F PS+ NI+L + + + E ++
Sbjct: 259 YIEVMIVSDSTMFEYHGNE-LENYLKTIMSIAANTFRSPSIMVNISLHVVRCLVLEAVEV 317
Query: 267 I-LKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG-----------GPSG 314
+ + + SL W R + +D +TR L G G
Sbjct: 318 DPMIVPDAQTSLRYFCDWQKRVYPENVGDPEHFDVATLITRHDLSRKDIFTGSTVHGVLG 377
Query: 315 FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
A + C ++R +I D GL + +AHE+ H
Sbjct: 378 LANMASACVRSRRCSIVEDNGLATGLTVAHEIGH 411
>UniRef50_A7T5R3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 483
Score = 62.5 bits (145), Expect = 2e-08
Identities = 43/144 (29%), Positives = 71/144 (49%), Gaps = 13/144 (9%)
Query: 215 DNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK----DIIL-K 269
D F+G ++ Y+LA+ N+ + ++ D S+G + + K+FL E DI+ K
Sbjct: 2 DKPTTDFYG-DKSMDYVLAIANMANRLYADKSVGFPLVFCLTKVFLIESNLPALDIVKNK 60
Query: 270 YGNIKKSLEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLG----GPSGFAPVGGVCTK 324
+ + L +KW + PEGS +D + LTR G G A G C+
Sbjct: 61 IDSASRYLHVFSKWF--QTVNTPEGSAEHFDNAVMLTRETCGINKCTLDGLAYFGSPCSS 118
Query: 325 TRSAAIDRDEGLTSAFVIAHELAH 348
+ A+++ GL +AF +AHE+AH
Sbjct: 119 SLGASVNDAYGLATAFSVAHEVAH 142
>UniRef50_UPI00006A1EB7 Cluster: ADAMTS-13 precursor (EC 3.4.24.-)
(A disintegrin and metalloproteinase with thrombospondin
motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand
factor-cleaving protease) (vWF-cleaving protease)
(vWF-CP).; n=1; Xenopus tropicalis|Rep: ADAMTS-13
precursor (EC 3.4.24.-) (A disintegrin and
metalloproteinase with thrombospondin motifs 13)
(ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving
protease) (vWF-cleaving protease) (vWF-CP). - Xenopus
tropicalis
Length = 763
Score = 62.1 bits (144), Expect = 2e-08
Identities = 47/161 (29%), Positives = 77/161 (47%), Gaps = 14/161 (8%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
+R GVK L EL +V + + +FH +E + Y+L +NI + D SLG+ + +
Sbjct: 1 KRAVGGVKHL--ELLVVVGHDVYQFH-QEDTERYVLTNLNIGVELLRDVSLGTAFRVHLV 57
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGW--DATIWLTRSQLGGPS 313
KL + + + ++ N+ SL ++ KW+ H + P+ S D +++TR L P
Sbjct: 58 KLIILTEPEADIQITTNLTSSLISLCKWS--HKVNPPDDSDPQHADLVLYVTRFDLELPD 115
Query: 314 GFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G V GG C+ S I D G +AHE+ H
Sbjct: 116 GNKQVRGVTQLGGACSSVWSCVITEDTGFDLGVTMAHEIGH 156
>UniRef50_UPI0000E81225 Cluster: PREDICTED: similar to ADAMTS13;
n=4; Gallus gallus|Rep: PREDICTED: similar to ADAMTS13 -
Gallus gallus
Length = 942
Score = 61.3 bits (142), Expect = 4e-08
Identities = 40/148 (27%), Positives = 73/148 (49%), Gaps = 8/148 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
LEL +VA + +H +E + YIL +NI + + D SLG++ + + ++ + + ++
Sbjct: 25 LELMVVAGPDVYMYH-QEDTERYILTNLNIGAELLRDASLGAHFRVHLMQMLVLREPEVN 83
Query: 268 LKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVGG 320
+ NI SL ++ +W+ + + D +++TR L P G +GG
Sbjct: 84 VNITTNITSSLISVCEWSKKVNPQNDSDPQHADIVLYVTRFDLQLPDGNKELRGVTRLGG 143
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
VC+ + S I +D G IAHE+ H
Sbjct: 144 VCSSSWSCVITQDTGFDLGVTIAHEIGH 171
>UniRef50_UPI0000D556A5 Cluster: PREDICTED: similar to ADAMTS-12
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12); n=1;
Tribolium castaneum|Rep: PREDICTED: similar to ADAMTS-12
precursor (A disintegrin and metalloproteinase with
thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12) -
Tribolium castaneum
Length = 1088
Score = 60.5 bits (140), Expect = 6e-08
Identities = 67/282 (23%), Positives = 111/282 (39%), Gaps = 37/282 (13%)
Query: 73 LKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQ 132
L ++E K + K C + TG + EEGS V ++ CDG L G + V + F ++P +
Sbjct: 119 LSVQERKIRKIDNDKMCHY-TGYIKGEEGSKVALSTCDG-LAGYITVREKRFFIEPVQEH 176
Query: 133 EKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHD 192
+ + ER Y GD +K
Sbjct: 177 APNAKGQHLHIIYER---YPQEGDLRTSQCGTSTNWEDAWRKRFFEKYSRGEFEKRSTES 233
Query: 193 MHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNIT 252
+H + LE +V D L+FH + Y+L +MN+V+ ++D S G+ +
Sbjct: 234 VHRY-----------LETMVVCDKKFLEFHKNIDQETYVLTVMNMVADFYHDSSSGNMMD 282
Query: 253 LVINKLFLYEDK-----DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRS 307
+V+ ++ LY DK D+++ N +L + KW + K D + LT
Sbjct: 283 VVVVRI-LYLDKEEEEIDLVIN-PNADDTLASFCKWQQKINPKDLANPNHHDIAVLLT-- 338
Query: 308 QLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
C+ AI+ D GL V+AHE+ H+
Sbjct: 339 ------------SACSGNEPCAINEDGGLVLGIVVAHEMGHV 368
>UniRef50_A7SQN5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1664
Score = 60.1 bits (139), Expect = 8e-08
Identities = 44/162 (27%), Positives = 74/162 (45%), Gaps = 13/162 (8%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
R+ + ++ ++E I D + ++G R Y LA+ N+ S +F D ++G + L +
Sbjct: 406 RKKRAVLETKYIETMITMDKSATDYYGN-RSMDYALAVANMASRLFGDGTVGFRLVLSLT 464
Query: 257 KLFLYEDKDIIL-----KYGNIKKSLEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLG 310
K+ L ED L K + L +KW+ + P G+ G +D + LTR G
Sbjct: 465 KVILIEDDLPALNITTNKIDSAADYLSVFSKWS--QTVNTPAGNAGHFDHAVLLTRDICG 522
Query: 311 GPS----GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G G C+ A+I+ GL +AF + H +AH
Sbjct: 523 MKECQLDGLTYFGSPCSNRLGASINNAYGLAAAFSVVHHMAH 564
>UniRef50_UPI000065D4F7 Cluster: Homolog of Homo sapiens "Von
Willebrand factor-cleaving protease precursor; n=1;
Takifugu rubripes|Rep: Homolog of Homo sapiens "Von
Willebrand factor-cleaving protease precursor - Takifugu
rubripes
Length = 1328
Score = 59.3 bits (137), Expect = 1e-07
Identities = 42/148 (28%), Positives = 66/148 (44%), Gaps = 8/148 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VINKLFLYEDKDI 266
LEL +V + + H ++ + YIL +NI S + D SLG N+ + ++ + L E +
Sbjct: 16 LELLVVVGPDVHQVH-KQDTERYILTNLNIASELLRDISLGGNMRVHLVRMIILSEPEPE 74
Query: 267 ILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVGG 320
I NI SL ++ +W + D +++TR L P G A +GG
Sbjct: 75 IQLSTNITSSLTSVCEWGRKINPANDSDPLHADLLLYITRYDLVLPDGNNQVRGVAQLGG 134
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
C+ S I D G I HE+ H
Sbjct: 135 ACSSEWSCVITEDTGFDLGITITHEIGH 162
>UniRef50_A7SPX7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 259
Score = 59.3 bits (137), Expect = 1e-07
Identities = 42/153 (27%), Positives = 76/153 (49%), Gaps = 11/153 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD M FHG ++ Y+ ++N+ ++ D S+G++I I KL ++E ++
Sbjct: 6 YIETLVVADYNMAAFHGTTKLNIYVPTILNVAYSLIGDNSIGADIKYKIKKLQIHEVENA 65
Query: 267 --ILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWD-ATIWLTR-------SQLG-GPSGF 315
++ + +L +W+ + +D AT+ + SQ+ +G
Sbjct: 66 NGLVISTSSSTTLSNFCQWSKGQNVGDDTNQDHFDHATLIASPGTTISYVSQIDVSVAGL 125
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
A + G+C S I++D GL SAF IAHE H
Sbjct: 126 ASLKGMCNPDLSCTINQDMGLGSAFTIAHETGH 158
>UniRef50_UPI0000D56749 Cluster: PREDICTED: similar to CG3622-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3622-PB, isoform B - Tribolium castaneum
Length = 942
Score = 58.4 bits (135), Expect = 3e-07
Identities = 40/136 (29%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 224 RERVKHYILALMNIVSAIFNDPSLGSNITLVINKL-FLYEDKDIILKYGNIKKSLEAINK 282
RE ++ ++LA++N V +++DPSLG + V+ +L L E+ +++ +I + L
Sbjct: 230 RELIR-FVLAMINAVQLLYHDPSLGRPVNFVLKRLEILKEEAAGLVRPPDIDRFLSNFCI 288
Query: 283 WNYRHLMKLPEGSTGWDATIWLT------RSQLGGPS----GFAPVGGVCTKTRSAAIDR 332
W WD + LT R + G S G APV G+CT T S ++
Sbjct: 289 WQRTKNPVGDREPQHWDHALILTGLDLYVRGKHGKISNQVVGLAPVAGMCTTTSSCTVNE 348
Query: 333 DEGLTSAFVIAHELAH 348
S +V+AHE+ H
Sbjct: 349 GRHFESVYVVAHEIGH 364
>UniRef50_Q76LX8 Cluster: ADAMTS-13 precursor; n=26; Tetrapoda|Rep:
ADAMTS-13 precursor - Homo sapiens (Human)
Length = 1427
Score = 58.4 bits (135), Expect = 3e-07
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>UniRef50_Q4S2G6 Cluster: Chromosome undetermined SCAF14761, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14761,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1518
Score = 56.8 bits (131), Expect = 8e-07
Identities = 42/149 (28%), Positives = 69/149 (46%), Gaps = 9/149 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSA-IFNDPSLGSNITL-VINKLFLYEDKD 265
LEL +V + + H ++ + YIL +NIV+ + D +LG+N+ + +++ + L E
Sbjct: 66 LELLVVVGPDVQQVH-KQDTERYILTNLNIVNTKLLRDMTLGANMRVHLVHMVALSEPDP 124
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG------FAPVG 319
I NI SL ++ +W + D +++TR L P G A +G
Sbjct: 125 EIQLSANITSSLRSVCEWGRKINPSNDSDPLHADLLLYITRYDLVLPDGNKQVRGVAQLG 184
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G C+ S I D G IAHE+ H
Sbjct: 185 GACSSEWSCVIAEDTGFDLGITIAHEIGH 213
>UniRef50_UPI0000F2AE75 Cluster: PREDICTED: similar to a
disintegrin-like and metalloprotease with thrombospondin
type 1 motif 14; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to a disintegrin-like and
metalloprotease with thrombospondin type 1 motif 14 -
Monodelphis domestica
Length = 1203
Score = 56.4 bits (130), Expect = 1e-06
Identities = 32/115 (27%), Positives = 61/115 (53%), Gaps = 8/115 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFL--YEDKD 265
+E+ + D+++++FHG+E V++Y+L LMNIV I++D SLG ++ + + ++ + Y
Sbjct: 408 IEVLLAVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHMNIALVRMIMVGYRQVS 467
Query: 266 IILKYGNIKKSLEAINKWNYRHLMK---LPEGSTGW---DATIWLTRSQLGGPSG 314
I+ +S + ++ +L++ L G W IW T Q G G
Sbjct: 468 SIINSERNSRSDQPLDSAGTLYLLQIEWLSRGLMEWCFKGHCIWKTSEQSYGQDG 522
Score = 39.5 bits (88), Expect = 0.13
Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQP 128
R P +EC FTG + G+AV ++ CDG L GL+++ E+ ++P
Sbjct: 292 RKPLQQEC-VFTGSITGMPGTAVAISNCDG-LAGLIRMDSSEYFIEP 336
>UniRef50_UPI0000586C6C Cluster: PREDICTED: similar to ADAMTS6
variant 2, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to ADAMTS6 variant 2,
partial - Strongylocentrotus purpuratus
Length = 220
Score = 53.2 bits (122), Expect = 1e-05
Identities = 19/57 (33%), Positives = 39/57 (68%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+E +V D +M+++H E ++ Y+L +MN+V+ + DPS+G+ + + + +L L ED+
Sbjct: 163 VETLVVVDQSMIEYHKDEDIETYVLTIMNLVAKFYRDPSIGNLVNIALVRLILLEDQ 219
>UniRef50_Q9W1Z6 Cluster: CG3622-PB, isoform B; n=5; Sophophora|Rep:
CG3622-PB, isoform B - Drosophila melanogaster (Fruit
fly)
Length = 1091
Score = 51.6 bits (118), Expect = 3e-05
Identities = 48/196 (24%), Positives = 86/196 (43%), Gaps = 28/196 (14%)
Query: 176 HVHP-RHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKF-------HGRERV 227
H HP +H + Y D R + + L++E AI D+ + + +V
Sbjct: 256 HHHPHQHHQQRRRRYIGDAPRSRW-SDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKV 314
Query: 228 KHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI--ILKYGNIKKSLEAINKW-- 283
++LA++N V +++ P+LG I V+ +L +++ D +++ +++ L + KW
Sbjct: 315 VSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQE 374
Query: 284 -----------NYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDR 332
+Y H + L TG D + G A V G+CT S I+
Sbjct: 375 KLNPFSDADPLHYDHALVL----TGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINE 430
Query: 333 DEGLTSAFVIAHELAH 348
+ S FV+AHE+ H
Sbjct: 431 AKHFESVFVVAHEIGH 446
>UniRef50_A7RTF2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1006
Score = 49.6 bits (113), Expect = 1e-04
Identities = 40/148 (27%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSN-ITLVINKLFLYEDKDI 266
LE+ I+AD ++ +G + + ++L L +I+ IF D ++G+ I +V+N++ L E
Sbjct: 181 LEVGIMADKAVMDVYG-DGITRHLLILAHIMRNIFLDQTIGTKKINVVVNQIILDESSFG 239
Query: 267 ILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGG------PSGFAPVGG 320
L AIN + +L + D + LT++ G G A
Sbjct: 240 YSSDSAPVDRLVAINAYATANLPRDDSDPGKPDMLLLLTKTSGGKCNIKKTSGGLAKSSS 299
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+C++ A+ + GL SA ++AHE AH
Sbjct: 300 LCSEMFGNALATNSGLGSAAIMAHETAH 327
>UniRef50_UPI0000584E04 Cluster: PREDICTED: similar to ADAM
metallopeptidase with thrombospondin type 1 motif, 3
proprotein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to ADAM metallopeptidase with
thrombospondin type 1 motif, 3 proprotein -
Strongylocentrotus purpuratus
Length = 503
Score = 49.2 bits (112), Expect = 2e-04
Identities = 20/35 (57%), Positives = 28/35 (80%)
Query: 315 FAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+APV G+C TRS ++++DEGL S+FVIAHE H+
Sbjct: 119 YAPVTGMCAITRSCSLNKDEGLLSSFVIAHESGHV 153
>UniRef50_Q9H2U9 Cluster: ADAM 7 precursor; n=24; Mammalia|Rep: ADAM
7 precursor - Homo sapiens (Human)
Length = 754
Score = 48.0 bits (109), Expect = 4e-04
Identities = 44/155 (28%), Positives = 82/155 (52%), Gaps = 16/155 (10%)
Query: 201 SGVKGL----WLELAIVADNTMLKFHG--RERVKHYILALMNIVSAIFNDPSLGSNITLV 254
S +KG+ ++EL IVAD+T+ + +G ++++ I ++N V+ I+ +L ++TLV
Sbjct: 190 SKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYK--TLNIHVTLV 247
Query: 255 INKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL-GGPS 313
+++ +EDK I Y NI+ +L + W K+ + +D + L+ L
Sbjct: 248 GIEIWTHEDK--IELYSNIETTLLRFSFWQ----EKILKTRKDFDHVVLLSGKWLYSHVQ 301
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + GG+C S +I +D L +IA+ +AH
Sbjct: 302 GISYPGGMCLPYYSTSIIKDL-LPDTNIIANRMAH 335
Score = 36.3 bits (80), Expect = 1.2
Identities = 14/60 (23%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 75 LKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEK 134
+K R P + F+ G ++HE SA +++ C+G L G ++ + ++++P + ++
Sbjct: 92 MKGGAFTRHPQIMDHCFYQGSIVHEYDSAASISTCNG-LRGFFRINDQRYLIEPVKYSDE 150
>UniRef50_UPI0001556104 Cluster: PREDICTED: similar to
aggrecanase-1, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to aggrecanase-1,
partial - Ornithorhynchus anatinus
Length = 560
Score = 47.6 bits (108), Expect = 5e-04
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG E +K Y+L +M + F PSL + ++LV+ +L + +
Sbjct: 150 FVETLVVADDKMAAFHG-EGLKRYLLTVMAAAAKAFRHPSLRNPVSLVVTRLVVLGPGEE 208
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGS--TGWDATIWLTRSQLGGPSGFAP 317
G N ++L A W + + PE S +D I TR GP P
Sbjct: 209 GPPVGPNAAETLRAFCAW--QRGLNPPEDSDPDHFDVAILFTRQVWAGPGPRGP 260
>UniRef50_UPI000065E1FF Cluster: Homolog of Homo sapiens "Splice
Isoform A of ADAMTS-14 precursor; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Splice Isoform A
of ADAMTS-14 precursor - Takifugu rubripes
Length = 1231
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Query: 238 VSAIFNDPSLGSNITLVINKLFL--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGS 295
V I++D SLG+NI +V+ ++ + Y +++ GN +SLE + +W + PE S
Sbjct: 362 VDEIYHDESLGTNINIVLVRMIMVGYRQSISLIERGNPSRSLEQVCRWANTQQRRDPEHS 421
Query: 296 TGWDATIWLTRSQLG 310
D I+LTR G
Sbjct: 422 EYHDHAIFLTRQDFG 436
Score = 45.6 bits (103), Expect = 0.002
Identities = 17/36 (47%), Positives = 26/36 (72%)
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G+APV G+C RS ++ ++G +SAFV+AHE H+
Sbjct: 472 GYAPVTGMCHPLRSCTLNHEDGFSSAFVVAHETGHV 507
Score = 43.6 bits (98), Expect = 0.008
Identities = 15/34 (44%), Positives = 29/34 (85%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAI 241
+E+ + D+++++FHG+E V++Y+L LMNIVS++
Sbjct: 299 IEVLLAVDDSVVRFHGKEHVQNYVLTLMNIVSSL 332
>UniRef50_Q5BVG6 Cluster: SJCHGC06709 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06709 protein - Schistosoma
japonicum (Blood fluke)
Length = 188
Score = 47.2 bits (107), Expect = 6e-04
Identities = 30/124 (24%), Positives = 66/124 (53%), Gaps = 8/124 (6%)
Query: 202 GVKGLWLELAIVADNTML-KFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINK-LF 259
G + W+E + AD+T++ +F + ++Y+ L+ + +F+ PSLG N++LVI ++
Sbjct: 63 GEQNYWIETLVFADHTVMNRFTNKTMAENYVKTLIRMTDELFHHPSLGVNLSLVIQDIIW 122
Query: 260 LYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPV 318
+ E + L +G ++ +S+ W H +D ++L+R+ + +G +P+
Sbjct: 123 VNEAESNELLWGVSLIRSVHRFCNWALTHHYV----RYNYDHALFLSRN-IVQAAGISPL 177
Query: 319 GGVC 322
+C
Sbjct: 178 SQMC 181
>UniRef50_A7SQN3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 420
Score = 47.2 bits (107), Expect = 6e-04
Identities = 58/228 (25%), Positives = 89/228 (39%), Gaps = 32/228 (14%)
Query: 85 YYKECQFFTGRVLHEEGSAVTVTEC-DGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVT 143
Y E F G V + S V V E QL G + GG E+ ++P H+ R+ D+
Sbjct: 115 YTPEGTFLQGHVTQDPRSHVAVRELGSNQLSGAIISGGHEYKIEPV---PHHIRRKMDLE 171
Query: 144 HSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV 203
G VI SH P D E RR
Sbjct: 172 GH---------GHHVISRRSLRSKR------SHAEP----FKDHEVSISKSASRRRRDLR 212
Query: 204 KGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
+ ++E I D F+G ++ Y+LA+ N+ + ++ D S+G + + K+FL E
Sbjct: 213 ETKYIEAMITMDKPTTDFYG-DKSMDYVLAIANMANRLYADKSVGFPLVFCLTKVFLIES 271
Query: 264 K----DIIL-KYGNIKKSLEAINKWNYRHLMKLPEGST-GWDATIWLT 305
DI+ K + + L +KW + PEGS +D + LT
Sbjct: 272 NLPALDIVKNKIDSASRYLHVFSKW--FQTVNTPEGSAEHFDNAVMLT 317
>UniRef50_UPI000155622B Cluster: PREDICTED: similar to ADAM
metallopeptidase domain 20 preproprotein, partial; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to ADAM
metallopeptidase domain 20 preproprotein, partial -
Ornithorhynchus anatinus
Length = 630
Score = 46.8 bits (106), Expect = 8e-04
Identities = 46/150 (30%), Positives = 67/150 (44%), Gaps = 13/150 (8%)
Query: 205 GLWLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYE 262
G +LELA+V DNT GR RV +L ++N+V ++ L + LV L ++
Sbjct: 16 GRFLELAVVVDNTRFDLSGRNQTRVLKQVLDVLNLVDTLYR--LLDVRVYLV--GLEIWT 71
Query: 263 DKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVC 322
D + + I K L N W HL LP S +D+ + G G A V +C
Sbjct: 72 DGNRVDVTRGIGKVLADFNAWQRTHL--LPRFS--YDSAHLIVNQPYGITLGLAYVKTIC 127
Query: 323 TKTRSAAIDR--DEGLTS-AFVIAHELAHL 349
++A+ D L A V AHE H+
Sbjct: 128 DNRYASAVQSFFDYRLLKLAVVFAHEQGHI 157
>UniRef50_Q177Y0 Cluster: Adam; n=2; Culicidae|Rep: Adam - Aedes
aegypti (Yellowfever mosquito)
Length = 1074
Score = 46.8 bits (106), Expect = 8e-04
Identities = 40/147 (27%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLK-FHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD 265
++EL +V DN + + +++ Y L L+N+++AI+ NI + + + ++ DKD
Sbjct: 192 YVELVLVIDNMLHRNIRNDQQIHRYCLDLVNVMNAIYRP----LNIYIALVGVVIWSDKD 247
Query: 266 IILKYGNIKKSLEAINKWNYRHLMK-LPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
I + KK+LEA + L+K +P + + T S +G A +G +CT
Sbjct: 248 QIEISLDSKKTLEAFLSYRRNTLLKMIPHDNAHLLTGVHFTDSVVGK----AEMGSMCTY 303
Query: 325 TRSA---AIDRDEGLTSAFVIAHELAH 348
S +D A IAHE+ H
Sbjct: 304 AGSGGVEVVDTKFVALQASTIAHEMGH 330
>UniRef50_Q22580 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 872
Score = 46.0 bits (104), Expect = 0.001
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 21/162 (12%)
Query: 206 LWLELAIVADNTML----KFHGR---ERVKHYILALMNIVSAIFNDPSLGSNITLVINKL 258
L +ELA+ AD+ M K +G+ E + +I+A++N + ++ L I + I +
Sbjct: 133 LTVELAVFADDAMWDHFKKMYGKAAEENMHTFIMAVVNNIDVLYTQRLLQPRINIKIVRY 192
Query: 259 FLYEDKDIILKY-----GNIKKSLEAINKWNYRHLMKLPEGSTG--WDATIW-----LTR 306
+ ++ ++ G++ + L+A + Y++ + P + WD + L R
Sbjct: 193 EILKNIPHLMNARKHSNGDVDRLLDAFCQ--YQNEINPPNDADPRHWDHALLFSGYDLHR 250
Query: 307 SQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ + +G+APV G+C+ RS I+ S FV+ HE+ H
Sbjct: 251 NGVKTVAGYAPVKGMCSGVRSCTINEGLDFGSVFVVTHEMGH 292
>UniRef50_A7SM43 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1136
Score = 44.8 bits (101), Expect = 0.003
Identities = 21/54 (38%), Positives = 36/54 (66%), Gaps = 1/54 (1%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLG-SNITLVINKLFL 260
LE+A+VAD ++K HG ++ ++L L ++V+ +F D S G + I LV+ KL +
Sbjct: 236 LEVAMVADQYVIKTHGEGKIADFMLMLAHVVNRMFQDESAGDTRIQLVVTKLVI 289
>UniRef50_P58459-3 Cluster: Isoform 3 of P58459 ; n=3; Murinae|Rep:
Isoform 3 of P58459 - Mus musculus (Mouse)
Length = 213
Score = 44.0 bits (99), Expect = 0.006
Identities = 18/34 (52%), Positives = 26/34 (76%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSA 240
++E +VAD M+ +HGR V+ Y+LA+MNIVSA
Sbjct: 174 YVETLVVADKMMVAYHGRRDVEQYVLAIMNIVSA 207
>UniRef50_A7RTF7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1124
Score = 44.0 bits (99), Expect = 0.006
Identities = 24/68 (35%), Positives = 45/68 (66%), Gaps = 3/68 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS-NITLVI 255
RR S +K ++ELA+VADN ++ G ++++ L ++ +A+F+D S+GS I+LV+
Sbjct: 159 RREESRLK--YMELALVADNYLITAMGERIAWYHLMMLAHLSNAMFHDESIGSQRISLVV 216
Query: 256 NKLFLYED 263
K+ + +D
Sbjct: 217 VKVIMKKD 224
>UniRef50_UPI0000E49875 Cluster: PREDICTED: similar to VWF-cleaving
protease Adamts-13; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to VWF-cleaving
protease Adamts-13 - Strongylocentrotus purpuratus
Length = 1216
Score = 43.6 bits (98), Expect = 0.008
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 31/158 (19%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR G K + E+ +VADN M F+G + V +Y L LMNI++
Sbjct: 322 RRETDGAKAM--EMLVVADNQMRLFYGPD-VANYTLILMNIITT---------------- 362
Query: 257 KLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTG-WDATIWLTRSQLGGPS-- 313
ED + + + +L + + Y H +L + +D +++TR +
Sbjct: 363 -----EDGATLNSVPDGELTLSSFCSYQY-HTNQLDDDHPDHYDNAVFITRHDIELKQNK 416
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G A + G C+ T +++ D G +S +IAHE+ H
Sbjct: 417 YLLGIANLRGACSATHQCSVNEDNGPSSGLIIAHEIGH 454
>UniRef50_Q4RN96 Cluster: Chromosome 1 SCAF15015, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 1
SCAF15015, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 821
Score = 43.6 bits (98), Expect = 0.008
Identities = 37/147 (25%), Positives = 65/147 (44%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL +VAD HG E+ K +L N+V + NI + + L ++ +
Sbjct: 228 YVELLLVADKAEFDKHGSNLEKTKLKLLEAANLVDKFYK----ALNIRVALIGLEVWTNG 283
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D+I N +L A W + L LP +A + R+ G G A + +C+
Sbjct: 284 DMISVSDNPHSTLAAFLSWRSKQLRALPND----NAQLITGRAFQGTTIGLAQLKAMCSD 339
Query: 325 TRSAAIDRDEGLTS---AFVIAHELAH 348
+S ++ D ++ A +AHE+ H
Sbjct: 340 YQSGGVNTDHSESAVGVAATMAHEMGH 366
>UniRef50_A7SQN0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 949
Score = 43.2 bits (97), Expect = 0.010
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 9/127 (7%)
Query: 226 RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNY 285
+V Y++ + ++ S + D ++ I + N FL K I G+ L + W
Sbjct: 265 KVIEYMITMDHVTSEFYKDRAV-DYIANLANMPFLNFTKHNIRSGGSY---LNRFSLWAE 320
Query: 286 RHLMKLPEGSTGWDATIWLTRSQLG----GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFV 341
+H P +D + +T+ G +G A G C SA+++ D+GL +AF
Sbjct: 321 QHNSP-PAAPEHFDNAVLITKRICGLADCSLNGLAFCGYSCESRYSASVNDDQGLQTAFS 379
Query: 342 IAHELAH 348
IAHE+AH
Sbjct: 380 IAHEMAH 386
>UniRef50_P20165 Cluster: Trimerelysin-2; n=46; Viperidae|Rep:
Trimerelysin-2 - Trimeresurus flavoviridis (Habu)
(Protobothrops flavoviridis)
Length = 201
Score = 43.2 bits (97), Expect = 0.010
Identities = 37/148 (25%), Positives = 67/148 (45%), Gaps = 14/148 (9%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++ELAIV D+ M K + + +++K + ++N ++ ++ NI + +N+L ++ K
Sbjct: 7 YIELAIVVDHGMYKKYNQNSDKIKVRVHQMVNHINEMYRP----LNIAISLNRLQIWSKK 62
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCT 323
D+I +LE+ W L+K D LT + L + G A G+C
Sbjct: 63 DLITVKSASNVTLESFGNWRETVLLKQQNN----DCAHLLTATNLNDNTIGLAYKKGMCN 118
Query: 324 KTRSAAIDRDEG---LTSAFVIAHELAH 348
S + +D A + HEL H
Sbjct: 119 PKLSVGLVQDYSPNVFMVAVTMTHELGH 146
>UniRef50_Q4SBC8 Cluster: Chromosome 11 SCAF14674, whole genome
shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 11
SCAF14674, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 2080
Score = 42.7 bits (96), Expect = 0.014
Identities = 19/36 (52%), Positives = 24/36 (66%)
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A +G VC RS +I D GL++AF IAHEL H+
Sbjct: 425 GLAELGTVCDPYRSCSIIEDNGLSTAFTIAHELGHV 460
Score = 39.1 bits (87), Expect = 0.17
Identities = 25/76 (32%), Positives = 45/76 (59%), Gaps = 19/76 (25%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNI------------------VSAIFNDPSLG 248
++E+ +VAD+ M++ HG ++HYIL LM+I VS+I+ DPS+G
Sbjct: 268 FVEVMLVADSKMVEHHG-SNLQHYILTLMSIVSPKVNRPLQTGVLERLAVSSIYKDPSIG 326
Query: 249 SNITLVINKLFLYEDK 264
+ I++V+ KL + ++
Sbjct: 327 NLISIVVVKLVIINNE 342
>UniRef50_A7SIV2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1029
Score = 42.3 bits (95), Expect = 0.018
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 9/149 (6%)
Query: 201 SGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS-NITLVINKLF 259
SGVK +LE ++AD+ + + +G E +Y+L + ++ +F S+G I LV+ +
Sbjct: 221 SGVK--YLETHMIADSFITEKYGEETT-NYLLMIAHVTRQVFLGGSVGDIKIHLVVVGIT 277
Query: 260 LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVG 319
L + + A+ W HL + +G + L + GG A G
Sbjct: 278 LNTGGFGYDSSASKVDRVSALTHWALTHLT-VDDGDRAHADVLVLMSNTTGG---IAVAG 333
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
C + D G+ SA ++AHE+AH
Sbjct: 334 STCNGL-GRTLAGDIGIQSALLVAHEIAH 361
>UniRef50_O43184 Cluster: ADAM 12 precursor; n=44; Euteleostomi|Rep:
ADAM 12 precursor - Homo sapiens (Human)
Length = 909
Score = 42.3 bits (95), Expect = 0.018
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 215 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 270
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 271 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 327
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 328 DQSGGIVMDHSDNPLGAAVTLAHELGH 354
>UniRef50_UPI0000E8086C Cluster: PREDICTED: similar to
metalloprotease-disintegrin; n=1; Gallus gallus|Rep:
PREDICTED: similar to metalloprotease-disintegrin -
Gallus gallus
Length = 775
Score = 41.5 bits (93), Expect = 0.032
Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 13/148 (8%)
Query: 207 WLELAIVADNT--MLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL +V DN + K V+ + L+N V +++ NI +V+ L ++ DK
Sbjct: 184 YVELFMVVDNHRFLQKNSDPAAVQKETVELINYVDGMYS----ALNIQIVLVGLEIWTDK 239
Query: 265 D-IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ I + G+ L W + L+K + + + R G G A VG VC+
Sbjct: 240 NQISVMEGSAGDVLGRFVSWRQKDLLKRSRNDV---SHLIIGRGSYNGSIGMAFVGTVCS 296
Query: 324 KTRSAAI---DRDEGLTSAFVIAHELAH 348
+ + +I + + L A V+AHEL H
Sbjct: 297 QVQGGSISTLNHNNVLRHATVVAHELGH 324
>UniRef50_UPI0000F2B1C1 Cluster: PREDICTED: similar to ADAM
metallopeptidase domain 20 preproprotein; n=1;
Monodelphis domestica|Rep: PREDICTED: similar to ADAM
metallopeptidase domain 20 preproprotein - Monodelphis
domestica
Length = 735
Score = 40.7 bits (91), Expect = 0.055
Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 14/147 (9%)
Query: 207 WLELAIVADNTMLKF-HGRE-RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+++L +V DN KF G E V + +L ++N++ +++ + N+ N + ++
Sbjct: 207 FVKLVVVVDNFWYKFARGNETEVIYQVLEVVNMIDSLYYPMFIYVNL----NGVEIWTSN 262
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+++ IK +L+ + W LP D T R G + VG +C
Sbjct: 263 NLVEFSKGIKVTLDVFSHWKRAINDWLPH-----DVTRLFVRYNFGIEKSLSYVGTICNN 317
Query: 325 TRSAAID---RDEGLTSAFVIAHELAH 348
SA ID D L + +AH L H
Sbjct: 318 VTSAGIDAYVEDNLLEFSITVAHGLGH 344
>UniRef50_A7SIU9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 980
Score = 40.7 bits (91), Expect = 0.055
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 7/143 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS-NITLVINKLFLYEDKD 265
+LE ++ADN + +G E + +L + ++ +F S G I LV+ + L
Sbjct: 201 YLETHMIADNFITSKYGNETT-NVLLMIAHVTRQVFLGGSAGDIKIHLVVVGITLNTGGL 259
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKT 325
+ + A+ W ++ S D + +T + G A G VC+ T
Sbjct: 260 GYTSSASKGDRIAALGTWMGTNIPSEDSNSAHADVVVLVTNTV----GGLAEAGSVCSST 315
Query: 326 RSAAIDRDEGLTSAFVIAHELAH 348
+ D G+ +A +AHE+AH
Sbjct: 316 GRVLVG-DTGIQTASAMAHEIAH 337
>UniRef50_P83512 Cluster: Hemorrhagic metalloproteinase BaP1; n=5;
Viperidae|Rep: Hemorrhagic metalloproteinase BaP1 -
Bothrops asper (Terciopelo)
Length = 203
Score = 40.7 bits (91), Expect = 0.055
Identities = 39/148 (26%), Positives = 69/148 (46%), Gaps = 14/148 (9%)
Query: 207 WLELAIVADNTML-KFHGR-ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++ELA+VAD+ + K++ ++ + ++N V+ + + + + L ++ +
Sbjct: 8 YIELAVVADHGIFTKYNSNLNTIRTRVHEMLNTVNGFYRSVDVHAPLA----NLEVWSKQ 63
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-GFAPVGGVCT 323
D+I + K+L++ +W R L LP S D LT G + G A GG+C
Sbjct: 64 DLIKVQKDSSKTLKSFGEWRERDL--LPRISH--DHAQLLTAVVFDGNTIGRAYTGGMCD 119
Query: 324 KTRSAAIDRD---EGLTSAFVIAHELAH 348
S + RD L A +AHEL H
Sbjct: 120 PRHSVGVVRDHSKNNLWVAVTMAHELGH 147
>UniRef50_Q13443 Cluster: ADAM 9 precursor; n=35; Euteleostomi|Rep:
ADAM 9 precursor - Homo sapiens (Human)
Length = 819
Score = 40.7 bits (91), Expect = 0.055
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR A + ++EL IV D GR + V+ ++ L N + +++ + NI
Sbjct: 201 LRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMY----IMLNIR 256
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+V+ L ++ + ++I G L +W + L+ D+ + + GG
Sbjct: 257 IVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH----DSAQLVLKKGFGGT 312
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGL---TSAFVIAHELAH 348
+G A VG VC+++ + I+ + T A ++AHEL H
Sbjct: 313 AGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGH 351
>UniRef50_Q9R159 Cluster: ADAM 25 precursor; n=5; Mus musculus|Rep:
ADAM 25 precursor - Mus musculus (Mouse)
Length = 760
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 16/148 (10%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+L+LA+V + +++H RV + ++NI++ I+ ++ LV+ + ++ ++
Sbjct: 222 FLDLALVVERERIRYHNNNTSRVLVEVFTIINIINNIYET----LDVELVLLGVEMWNER 277
Query: 265 DIILKYGNIKKSLEAINKWNYRHL-MKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ + + +I++ L+ W R L ++P D + G G A +G VC
Sbjct: 278 NHV-QVRSIEELLDEFCMWKARSLNFRIPN-----DIAHIFVNHEFGIYLGLAYIGSVCV 331
Query: 324 KTRSAAIDRDEGLTSAF---VIAHELAH 348
+ + +DR G + +IAHE+ H
Sbjct: 332 PSHNCGVDRLLGGNLFYFGRIIAHEMGH 359
Score = 34.3 bits (75), Expect = 4.8
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 84 PYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQE--KHVLRRRD 141
PY + ++ G + + S V +T C G G+LQ+ G + ++P +H++ + D
Sbjct: 118 PYVQNDCYYHGHMDGDPESMVAITTCYGGFQGILQINGTVYEIKPKNLSSTFEHLVHKMD 177
Query: 142 VTHSE 146
+E
Sbjct: 178 SEETE 182
>UniRef50_UPI0000E25573 Cluster: PREDICTED: ADAM metallopeptidase
domain 33; n=1; Pan troglodytes|Rep: PREDICTED: ADAM
metallopeptidase domain 33 - Pan troglodytes
Length = 622
Score = 39.9 bits (89), Expect = 0.097
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +I +V+ L ++ ++
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLRT----LDIQVVLAGLEVWTER 266
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + +L A +W + P S A + R+ G G APV G+C
Sbjct: 267 DRSRVTQDANATLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>UniRef50_O12960 Cluster: ADAM 13; n=3; Xenopus|Rep: ADAM 13 -
Xenopus laevis (African clawed frog)
Length = 914
Score = 39.9 bits (89), Expect = 0.097
Identities = 36/147 (24%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVAD +M R K +L + N V + + NI + + L ++ ++
Sbjct: 206 YMELFIVADYSMFMKQNRNLGSTKQRVLEIANYVDKFY----MSMNIKVALIGLEVWTER 261
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL++ +W KL +A + + G G AP+ G+CT
Sbjct: 262 DQCEVNDDANDSLKSFLQWK----QKLRSRKKHDNAQLITGVTFKGTTIGMAPLEGMCTA 317
Query: 325 TRSAAIDRD---EGLTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 318 ENSGGVSMDHSENAIGAAATMAHEIGH 344
>UniRef50_Q9BZ11 Cluster: ADAM 33 precursor; n=29; Tetrapoda|Rep:
ADAM 33 precursor - Homo sapiens (Human)
Length = 813
Score = 39.9 bits (89), Expect = 0.097
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>UniRef50_UPI0000F1E743 Cluster: PREDICTED: similar to ADAM13; n=3;
Danio rerio|Rep: PREDICTED: similar to ADAM13 - Danio
rerio
Length = 1041
Score = 39.5 bits (88), Expect = 0.13
Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 14/157 (8%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLV 254
RR A G ++EL IVADNT+ + + ++ K I+ + N V + + L + L+
Sbjct: 303 RRNAWGTTK-YMELYIVADNTLYRKQNKDLDKTKLRIMEIANYVDKFYRE--LNIRVPLI 359
Query: 255 INKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSG 314
+++ D+ II + N +L + +W KL +A + G G
Sbjct: 360 GLEVWTEHDQCIINEEPN--STLWSFLQWR----QKLKSRKKHDNAQLLTGVIFKGTTIG 413
Query: 315 FAPVGGVCTKTRSAAIDRDEG---LTSAFVIAHELAH 348
AP+ G+C+ S I+ D + +A +AHE+ H
Sbjct: 414 MAPLEGMCSHENSGGINVDHSELPIGAAATMAHEIGH 450
>UniRef50_UPI0000E81538 Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 1322
Score = 38.7 bits (86), Expect = 0.22
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 13/146 (8%)
Query: 207 WLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LE+ ++ D + G ++ V I+ L + V+++F N+T+V+ L L+ +K
Sbjct: 862 YLEMHVILDKALYDHMGADKYVVTTKIVRLFSYVNSMFTR----LNLTIVLTSLELWTEK 917
Query: 265 DIILKYGNIKKSLEAINKW-NYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ IL G ++ L+ +W N +H ++L D T + P G + +C
Sbjct: 918 NKILTTGGAEELLQRFLQWKNTQHTLRLQ------DITFLFVYREQPHPVGASSARKLCL 971
Query: 324 KTRSAAIDRDEGLTSAFVIAHELAHL 349
K R+ + T+ V + +A L
Sbjct: 972 KDRAGGVALFPRATTLEVFSVAVAQL 997
>UniRef50_UPI0000660B5D Cluster: Homolog of Homo sapiens "Splice
Isoform 1 of ADAMTS-12 precursor; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Splice Isoform 1
of ADAMTS-12 precursor - Takifugu rubripes
Length = 151
Score = 37.5 bits (83), Expect = 0.52
Identities = 15/41 (36%), Positives = 25/41 (60%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNI 237
R S K W+E +VAD+ ++ +HG + V+ YI +MN+
Sbjct: 45 RSQRSVSKERWVESMVVADSKLIDYHGSDNVESYIFTIMNM 85
>UniRef50_Q4SEB0 Cluster: Chromosome 2 SCAF14623, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF14623, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 524
Score = 37.5 bits (83), Expect = 0.52
Identities = 41/147 (27%), Positives = 62/147 (42%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK + + N V + NI + + L ++ D
Sbjct: 12 YVELIIVADNREFQKQGKDMEKVKQRLAEIANYVDKFYR----ALNIRVALVGLEVWSDV 67
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + +L W R + LP+ I Q G G AP+ +CT
Sbjct: 68 DKCPITQDPFTTLHEFLDW--RKVKLLPQKPHDNAQLISGVYFQ-GTTIGMAPIMSMCTA 124
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 125 EQSGGIVMDHSDNPLGAAVTLAHELGH 151
>UniRef50_UPI0000D9BA61 Cluster: PREDICTED: similar to a
disintegrin-like and metalloprotease (reprolysin type)
with thrombospondin type 1 motif, 7; n=1; Macaca
mulatta|Rep: PREDICTED: similar to a disintegrin-like
and metalloprotease (reprolysin type) with
thrombospondin type 1 motif, 7 - Macaca mulatta
Length = 359
Score = 37.1 bits (82), Expect = 0.68
Identities = 15/35 (42%), Positives = 21/35 (60%)
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + V G+C S +I++D GL F +AHEL H
Sbjct: 279 GLSHVAGICLPHCSCSINKDTGLPLGFTVAHELGH 313
>UniRef50_Q8IU50 Cluster: ADAMTS-like protease; n=5;
Caenorhabditis|Rep: ADAMTS-like protease -
Caenorhabditis elegans
Length = 1020
Score = 37.1 bits (82), Expect = 0.68
Identities = 60/271 (22%), Positives = 100/271 (36%), Gaps = 35/271 (12%)
Query: 98 HEEGSAV--TVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTG 155
H G V ++ CDG++ G + GE V+ P H +R +E A
Sbjct: 110 HHYGEKVYAAISNCDGRIKGTVIDDGEIIVVHPFPDHHAHRSKRA----TENGAHVVYKR 165
Query: 156 DTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVAD 215
+T+ V + F D+ + + + L +ELA+ D
Sbjct: 166 ETLAGEPKDFCGLDNV-----VTEESLVEDESAIFEDVFVTGQRLTQQSDLIVELAVFVD 220
Query: 216 NTMLKF----HGR---ERVKHYILALMNIVSAIFNDPSLGSNITL-VINKLFLYEDKDII 267
+ + HG +++ Y L L+N + ++ P+ +T VI L +
Sbjct: 221 ENLWRHFSSKHGGMADRKLQDYTLTLLNNIQIMYYQPTASPPLTFRVIRYEVLTRQPSAL 280
Query: 268 LKY----GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---GGP---SGFAP 317
Y GN + L+ ++ R+L WD I LT + G SG A
Sbjct: 281 AGYLHNHGNAQMYLDRFCRYQ-RNL-----AVRDWDHAIMLTGYDIHRGAGSRSISGIAR 334
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ G+C + + TSAF+ HEL H
Sbjct: 335 LDGMCDPWNTCTLAEGLDFTSAFIGTHELGH 365
>UniRef50_Q90495 Cluster: Ecarin precursor; n=151; Colubroidea|Rep:
Ecarin precursor - Echis carinatus (Saw-scaled viper)
Length = 616
Score = 37.1 bits (82), Expect = 0.68
Identities = 54/274 (19%), Positives = 111/274 (40%), Gaps = 39/274 (14%)
Query: 83 SPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRRR 140
+P ++ ++ GR+ ++ S +++ C+G L G ++ GE + ++P + E H + +
Sbjct: 99 NPSVEDHCYYHGRIQNDAESTASISACNG-LKGHFKLRGETYFIEPLKIPDSEAHAVYKY 157
Query: 141 DVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPA 200
+ +E A + G + + P H +K++
Sbjct: 158 ENIENEDEAP-KMCG---VTQDNWESDEPIKKTLGLIVPPHERKFEKKF----------- 202
Query: 201 SGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKL 258
+EL +V D++M+ + + ++ +I ++N V+ I+ L NI + + L
Sbjct: 203 -------IELVVVVDHSMVTKYNNDSTAIRTWIYEMLNTVNEIY----LPFNIRVALVGL 251
Query: 259 FLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDAT-IWLTRSQLGGPSGFAP 317
+ + D+I +L + +W L+ T + L S LG
Sbjct: 252 EFWCNGDLINVTSTADDTLHSFGEWRASDLLNRKRHDHAQLLTNVTLDHSTLG----ITF 307
Query: 318 VGGVCTKTRSAAIDRDEG---LTSAFVIAHELAH 348
V G+C RS + D A++IAHE+ H
Sbjct: 308 VYGMCKSDRSVELILDYSNITFNMAYIIAHEMGH 341
>UniRef50_UPI0000F2C443 Cluster: PREDICTED: similar to cysteine-rich
glycoprotein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to cysteine-rich glycoprotein - Monodelphis
domestica
Length = 832
Score = 36.3 bits (80), Expect = 1.2
Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 14/147 (9%)
Query: 207 WLELAIVADNTML-KFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD 265
++EL +V DNT K+ V+ + ++N V ++ + N +V+ L +++ D
Sbjct: 296 YVELFVVVDNTEYQKYKSLSTVRQRVKEIVNHVDRLYQE----INFRVVLIGLEIWDQAD 351
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP-SGFAPVGGVCTK 324
N+ +L + +W HL+ G D +T G G + +CT+
Sbjct: 352 KAAINSNVHSALASFLRWRESHLI----GKKSHDNAQLITGVSFEGTIVGMGRLASMCTE 407
Query: 325 TRSAAIDRD---EGLTSAFVIAHELAH 348
S ++ D L A +AHE+ H
Sbjct: 408 -GSGGVNHDYSENPLGVATSVAHEMGH 433
>UniRef50_Q2VYF6 Cluster: Metalloproteinase 12-like protein; n=3;
Homo/Pan/Gorilla group|Rep: Metalloproteinase 12-like
protein - Homo sapiens (Human)
Length = 629
Score = 36.3 bits (80), Expect = 1.2
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>UniRef50_Q8TC27 Cluster: ADAM 32 precursor; n=22; Eutheria|Rep:
ADAM 32 precursor - Homo sapiens (Human)
Length = 787
Score = 36.3 bits (80), Expect = 1.2
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>UniRef50_Q45R49 Cluster: Salivary gland metalloprotease; n=1;
Rhipicephalus microplus|Rep: Salivary gland
metalloprotease - Boophilus microplus (Cattle tick)
Length = 492
Score = 35.9 bits (79), Expect = 1.6
Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 261 YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGG 320
YE IL IK E + K Y + TG + W + G+A VGG
Sbjct: 248 YEQYRNILYGQTIKNFNEHVKKQVYFERSDIVFLLTGMSMSAWENGALQHWVGGYAYVGG 307
Query: 321 VCTKTR-SAAIDRDEGLTSAFVIAHELAH 348
CT R + +R +V AHELAH
Sbjct: 308 ACTAWRVGMSEERVGSYYGVYVYAHELAH 336
>UniRef50_Q4RE58 Cluster: Chromosome 2 SCAF15135, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15135, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 647
Score = 35.5 bits (78), Expect = 2.1
Identities = 40/159 (25%), Positives = 67/159 (42%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR + + ++EL +V DN F + V+ + L N++ + NI
Sbjct: 91 LLRRKRNLPQTSYVELVLVVDNLRYNFKKQNETAVREETVELANLLDGYYKM----LNIR 146
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+++ L +++D + G+ L W L LP+ D + GG
Sbjct: 147 VMLIGLVIFKDSNPFSVEGSAGDVLGRFVDWRKTSL--LPK--LRHDIGQLIVPESYGGV 202
Query: 313 SGFAPVGGVCTKTRSAAID--RDEGLT-SAFVIAHELAH 348
G A VG VC+ + S I+ D L + V+AHE+ H
Sbjct: 203 LGMAFVGTVCSASTSGGINVFSDNSLPYFSTVVAHEMGH 241
>UniRef50_UPI00015B4A24 Cluster: PREDICTED: similar to
metalloprotease; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to metalloprotease - Nasonia
vitripennis
Length = 334
Score = 35.1 bits (77), Expect = 2.7
Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 19/162 (11%)
Query: 206 LWLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+ +L +V D + K G++ R Y+ NIV + + +++ + + ED
Sbjct: 110 LYPKLLVVVDYHLFKLLGKDVTRTVRYVATFWNIVDQKYERLET-PKVQVIVTGIVIVED 168
Query: 264 K---DIILKYGNIKKSLEAINKWNYRHLMKLPE-----GSTGWDATIWLTRSQLGGPSGF 315
+ + I + N + + Y L + +DA I +T ++ GF
Sbjct: 169 EKALNFIYRSRNETEKADIDQLMEYSRLYFSQDFVNDTSFKNYDAAILMTGLKMNLIEGF 228
Query: 316 -------APVGGVCTKTRSAAIDRDEGLTSAFVIA-HELAHL 349
A +GG+C++ + AI D G +IA HEL HL
Sbjct: 229 FEISGLAAKLGGICSRQYNVAIVTDSGAYRNTLIAIHELGHL 270
>UniRef50_UPI0000F2BB07 Cluster: PREDICTED: similar to epididymal
apical protein I-; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to epididymal apical protein I- -
Monodelphis domestica
Length = 768
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/60 (26%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTR--TQEKHVLRRRDVTHSERS 148
++ G +LHE+ SA +++ CDG L G + + ++++P Q +H + + D +R+
Sbjct: 102 YYQGHILHEKDSAASISTCDG-LRGYFRQHDQRYLIEPLEHTDQGEHAIFKYDHKAQDRT 160
>UniRef50_UPI0000DB7008 Cluster: PREDICTED: similar to CG3622-PB,
isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG3622-PB, isoform B - Apis mellifera
Length = 723
Score = 34.7 bits (76), Expect = 3.6
Identities = 44/172 (25%), Positives = 73/172 (42%), Gaps = 29/172 (16%)
Query: 206 LWLELAIVADNT----MLKFHGR--ERVKHYILALMNIVSAIFNDPSLGS--NITLVINK 257
L LELA+ D T F R E++ +LA +N + A+++ PSLG +I+LV +
Sbjct: 197 LTLELALFFDETGYNLFSPFFDRNDEKILDMLLAYINGIQAVYHHPSLGIAIDISLVRLE 256
Query: 258 LFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL----GGPS 313
+ + +D+ G K L++ + ++ WD ++++ GG
Sbjct: 257 IMQKQPEDLPHHDGERGKLLDSFCNYAKKNNPANEFNPNHWDMGLYVSGLDFYVMEGGQK 316
Query: 314 -----GFAPVGGVCTKTRSAAIDR------------DEGLTSAFVIAHELAH 348
G A V G+C + S I G TS +V AHE+ H
Sbjct: 317 NSATMGLAIVNGLCIEQYSCVIAELGVTNQFGKPFPSAGFTSIYVAAHEMGH 368
>UniRef50_Q09JT3 Cluster: Metalloprotease; n=1; Argas
monolakensis|Rep: Metalloprotease - Argas monolakensis
Length = 293
Score = 34.7 bits (76), Expect = 3.6
Identities = 13/39 (33%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 311 GPSGFAPVGGVCTKTRSAAIDRDEG-LTSAFVIAHELAH 348
G +G+ +GGVC + ++ A + + G + ++ AHE+AH
Sbjct: 38 GTAGYTMLGGVCNEYKTGAAEDEAGSYSGVYITAHEIAH 76
>UniRef50_Q64S53 Cluster: Putative uncharacterized protein; n=2;
Bacteroides fragilis|Rep: Putative uncharacterized
protein - Bacteroides fragilis
Length = 428
Score = 34.3 bits (75), Expect = 4.8
Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 293 EGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHEL 346
E + GW+ T+ ++ + A G+ T T ++AI+ EG T + +AHEL
Sbjct: 316 EATAGWEYTVSPEKALMNAGVDAADAQGMAT-TINSAIEAQEGTTGTYKVAHEL 368
>UniRef50_UPI00001CC78C Cluster: PREDICTED: similar to ADAM
metallopeptidase domain 21 preproprotein; n=3; Rattus
norvegicus|Rep: PREDICTED: similar to ADAM
metallopeptidase domain 21 preproprotein - Rattus
norvegicus
Length = 780
Score = 33.9 bits (74), Expect = 6.3
Identities = 17/65 (26%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 84 PYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQP--TRTQEKHVLRRRD 141
P+ + ++ G V + S VT+T C G + G+LQ G + ++P +H++ + D
Sbjct: 103 PFVQNDCYYHGYVEGDPNSMVTLTTCLGNIQGMLQTNGITYEIKPKVVSATFEHLVYKMD 162
Query: 142 VTHSE 146
+ +E
Sbjct: 163 MEDTE 167
>UniRef50_Q5ZRV1 Cluster: NADH dehydrogenase I, N subunit; n=4;
Legionella pneumophila|Rep: NADH dehydrogenase I, N
subunit - Legionella pneumophila subsp. pneumophila
(strain Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 490
Score = 33.5 bits (73), Expect = 8.4
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 210 LAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILK 269
LA+++D + H + + YI + IVSA + +GS L+ NKLF+ +D ++K
Sbjct: 33 LALLSD--LFFRHKLKSIAFYISCVGIIVSAAVSFVFIGSYKLLIFNKLFISDDISHLMK 90
Query: 270 -YGNIKKSLEAINKWNYRHLMKLPEG 294
+ +I L + NY ++P G
Sbjct: 91 LFIDITVLLSFVYSQNYLDERQMPTG 116
>UniRef50_A1GFB5 Cluster: 3-Oxoacyl-(Acyl-carrier-protein (ACP))
synthase III C terminal; n=1; Salinispora arenicola
CNS205|Rep: 3-Oxoacyl-(Acyl-carrier-protein (ACP))
synthase III C terminal - Salinispora arenicola CNS205
Length = 343
Score = 33.5 bits (73), Expect = 8.4
Identities = 17/50 (34%), Positives = 22/50 (44%)
Query: 262 EDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGG 311
ED+D+ G+ E I +W YR + PEG T D R L G
Sbjct: 19 EDQDVAQVAGDYVDDPERIIRWGYRTFHRAPEGVTATDLAADAARKALAG 68
>UniRef50_A0UVG5 Cluster: Transcriptional regulator, AraC family;
n=1; Clostridium cellulolyticum H10|Rep: Transcriptional
regulator, AraC family - Clostridium cellulolyticum H10
Length = 779
Score = 33.5 bits (73), Expect = 8.4
Identities = 15/40 (37%), Positives = 27/40 (67%)
Query: 233 ALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGN 272
A+ +I++ +FN + SN++ ++KLF+YE II+K N
Sbjct: 584 AVKSILNLLFNKNFIDSNLSTSLHKLFIYELLGIIIKLWN 623
>UniRef50_Q16GK9 Cluster: Adam; n=2; Culicidae|Rep: Adam - Aedes
aegypti (Yellowfever mosquito)
Length = 830
Score = 33.5 bits (73), Expect = 8.4
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL +V DN++ ++ + V Y ++N V+ +FN NI + + + +++
Sbjct: 176 YVELVLVVDNSLYRYFNSDIWTVHRYCTDVVNHVNMLFNQ----LNIFIALTGVVVWDQH 231
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I +L ++ + L+ T + + G A +GG+CT
Sbjct: 232 DHIHVSDRADDTLNNFLQYRRKELLLSHPNDHAQLLTAVNFQDHVIGK---AKLGGMCTS 288
Query: 325 TRSAA---IDRDEGLTSAFVIAHELAH 348
S A I D A +AHE+ H
Sbjct: 289 NNSGAVIVIHTDNIGIQAGTLAHEMGH 315
>UniRef50_A7SIV0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 772
Score = 33.5 bits (73), Expect = 8.4
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 277 LEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGL 336
L A+ KW +L + D + + S + G G A G +C+ + D GL
Sbjct: 49 LSALGKWASTNLPTDDSNAAHPDVIVLI--SSISG--GLAGAGSICSGL-GKTVSGDIGL 103
Query: 337 TSAFVIAHELAH 348
+A +IAHE+AH
Sbjct: 104 QTAVIIAHEVAH 115
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.136 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 352,449,201
Number of Sequences: 1657284
Number of extensions: 13106031
Number of successful extensions: 28297
Number of sequences better than 10.0: 133
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 28054
Number of HSP's gapped (non-prelim): 182
length of query: 349
length of database: 575,637,011
effective HSP length: 101
effective length of query: 248
effective length of database: 408,251,327
effective search space: 101246329096
effective search space used: 101246329096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 73 (33.5 bits)
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