Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002474-TA|BGIBMGA002474-PA|IPR001590|Peptidase M12B,
ADAM/reprolysin
(349 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w... 133 1e-30
AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w... 133 1e-30
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte... 133 1e-30
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ... 133 1e-30
AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w... 129 1e-29
AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w... 129 1e-29
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein. 129 1e-29
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein... 116 9e-26
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein. 116 1e-25
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w... 116 1e-25
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein. 116 1e-25
AB209497-1|BAD92734.1| 527|Homo sapiens a disintegrin and metal... 106 1e-22
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida... 103 9e-22
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w... 103 1e-21
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein. 103 1e-21
AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease AD... 103 1e-21
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein. 97 6e-20
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ... 97 6e-20
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot... 95 3e-19
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein. 95 4e-19
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w... 94 6e-19
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ... 94 6e-19
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein. 94 6e-19
AY692425-1|AAW47398.1| 468|Homo sapiens ADAMTS6 variant 3 protein. 93 1e-18
AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease AD... 93 1e-18
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w... 93 1e-18
BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase w... 92 3e-18
BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase w... 92 3e-18
AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein. 92 3e-18
BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase w... 89 2e-17
AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease disinte... 89 2e-17
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w... 89 3e-17
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte... 89 3e-17
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein. 88 4e-17
DQ266047-1|ABB70405.1| 570|Homo sapiens ADAMTS16s alternative s... 87 9e-17
AP001698-1|BAA95504.1| 412|Homo sapiens disintegrin-like and me... 87 9e-17
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte... 87 9e-17
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein. 87 9e-17
BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase w... 86 2e-16
AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with th... 86 2e-16
AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease ... 86 2e-16
AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with ... 86 2e-16
AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein. 86 2e-16
AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein. 86 2e-16
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein. 85 5e-16
AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein. 77 9e-14
BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase w... 77 1e-13
AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein. 76 2e-13
AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase w... 76 2e-13
AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein. 76 2e-13
AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein. 76 2e-13
BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein. 73 2e-12
AF175283-1|AAF25806.1| 246|Homo sapiens zinc metalloendopeptida... 73 2e-12
AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein. 73 2e-12
BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein. 70 1e-11
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ... 69 2e-11
AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and ... 69 2e-11
AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein. 69 3e-11
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein. 69 3e-11
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w... 58 3e-08
BC103829-1|AAI03830.1| 276|Homo sapiens ADAMTS13 protein protein. 58 3e-08
BC103828-1|AAI03829.1| 276|Homo sapiens ADAMTS13 protein protein. 58 3e-08
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c... 58 3e-08
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ... 58 3e-08
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ... 58 3e-08
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w... 58 3e-08
AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ... 58 3e-08
AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ... 58 3e-08
AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ... 58 3e-08
AJ420811-1|CAD12730.1| 344|Homo sapiens ADAMTS-13 protein, trun... 58 3e-08
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari... 58 3e-08
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein. 58 3e-08
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein. 58 3e-08
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c... 58 3e-08
AK129873-1|BAC85245.1| 226|Homo sapiens protein ( Homo sapiens ... 55 3e-07
AF215824-1|AAG43987.1| 754|Homo sapiens a disintegrin and metal... 48 5e-05
AF090327-1|AAC36742.1| 588|Homo sapiens sperm maturation-relate... 48 5e-05
BC060804-1|AAH60804.1| 737|Homo sapiens ADAM metallopeptidase d... 42 0.002
AY692426-1|AAW47399.1| 292|Homo sapiens ADAMTS6 variant 4 protein. 42 0.002
AY358878-1|AAQ89237.1| 735|Homo sapiens ADAM-12 protein. 42 0.002
AL589787-6|CAI40683.1| 738|Homo sapiens ADAM metallopeptidase d... 42 0.002
AL589787-5|CAI40682.1| 909|Homo sapiens ADAM metallopeptidase d... 42 0.002
AF023477-1|AAC08703.2| 738|Homo sapiens meltrin-S protein. 42 0.002
AF023476-1|AAC08702.2| 909|Homo sapiens meltrin-L precursor pro... 42 0.002
BC030812-1|AAH30812.1| 339|Homo sapiens ADAMTS4 protein protein. 42 0.003
AL590714-7|CAH72147.1| 339|Homo sapiens ADAM metallopeptidase w... 42 0.003
U41766-1|AAC50403.1| 819|Homo sapiens metalloprotease/disintegr... 41 0.007
D14665-1|BAA03499.2| 703|Homo sapiens KIAA0021 protein protein. 41 0.007
BC126406-1|AAI26407.1| 712|Homo sapiens ADAM9 protein protein. 41 0.007
AF495383-1|AAM49575.1| 655|Homo sapiens disintegrin/metalloprot... 41 0.007
DQ995342-1|ABI97387.1| 813|Homo sapiens ADAM metallopeptidase d... 40 0.013
AY358314-1|AAQ88680.1| 813|Homo sapiens Adam33 protein. 40 0.013
AL356755-2|CAI23465.1| 813|Homo sapiens ADAM metallopeptidase d... 40 0.013
AL356755-1|CAM28348.1| 812|Homo sapiens ADAM metallopeptidase d... 40 0.013
AL109804-2|CAI18840.1| 813|Homo sapiens ADAM metallopeptidase d... 40 0.013
AL109804-1|CAM26955.1| 812|Homo sapiens ADAM metallopeptidase d... 40 0.013
AF466288-1|AAM80483.1| 812|Homo sapiens a disintegrin and metal... 40 0.013
AF466287-1|AAM80482.1| 812|Homo sapiens a disintegrin and metal... 40 0.013
AB055891-1|BAB83092.1| 813|Homo sapiens metalloprotease disinte... 40 0.013
BC058037-1|AAH58037.1| 210|Homo sapiens ADAM7 protein protein. 36 0.16
BC034975-1|AAH34975.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
BC030698-1|AAH30698.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
BC030014-1|AAH30014.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
BC028702-1|AAH28702.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
BC026169-1|AAH26169.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
BC026085-1|AAH26085.1| 787|Homo sapiens ADAM metallopeptidase d... 36 0.16
AY358739-1|AAQ89099.1| 787|Homo sapiens similar to MDC family p... 36 0.16
AY172952-1|AAO45696.1| 629|Homo sapiens metalloproteinase 12-li... 36 0.16
AB209690-1|BAD92927.1| 279|Homo sapiens ADAM 32 precursor (A di... 36 0.16
AY532929-1|AAS54901.1| 90|Homo sapiens von Willebrand factor-c... 34 0.65
BC126253-1|AAI26254.1| 512|Homo sapiens ADAM10 protein protein. 33 1.1
AF009615-1|AAC51766.1| 748|Homo sapiens ADAM10 protein. 33 1.1
X99374-1|CAA67753.1| 735|Homo sapiens fertilin beta protein. 33 2.0
U52370-1|AAC51110.1| 735|Homo sapiens fertilin beta protein. 33 2.0
U38805-1|AAD04206.1| 734|Homo sapiens fertilin beta protein. 33 2.0
AJ133005-1|CAB40813.1| 735|Homo sapiens fertilin beta protein p... 33 2.0
BC035515-1|AAH35515.1| 324|Homo sapiens chromosome 5 open readi... 31 4.6
BC132765-1|AAI32766.1| 832|Homo sapiens ADAM metallopeptidase d... 31 8.0
BC132763-1|AAI32764.1| 832|Homo sapiens ADAM metallopeptidase d... 31 8.0
AJ005580-1|CAC20565.1| 832|Homo sapiens Adam23 protein protein. 31 8.0
AC009225-1|AAX93195.1| 579|Homo sapiens unknown protein. 31 8.0
AB009672-1|BAA32351.1| 832|Homo sapiens MDC3 protein. 31 8.0
>AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 133 bits (321), Expect = 1e-30
Identities = 84/272 (30%), Positives = 141/272 (51%), Gaps = 17/272 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAP 317
+ Y +++ GN +SLE + +W + + P + D ++LTR GPSG+AP
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDF-GPSGYAP 371
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
V G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 372 VTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 403
>AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 133 bits (321), Expect = 1e-30
Identities = 84/272 (30%), Positives = 141/272 (51%), Gaps = 17/272 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAP 317
+ Y +++ GN +SLE + +W + + P + D ++LTR GPSG+AP
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDF-GPSGYAP 371
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
V G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 372 VTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 403
>AJ345098-1|CAC87943.1| 1223|Homo sapiens
metalloprotease-disintegrin protease protein.
Length = 1223
Score = 133 bits (321), Expect = 1e-30
Identities = 84/272 (30%), Positives = 141/272 (51%), Gaps = 17/272 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAP 317
+ Y +++ GN +SLE + +W + + P + D ++LTR GPSG+AP
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDF-GPSGYAP 371
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
V G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 372 VTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 403
>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motif 14 prec
protein.
Length = 1223
Score = 133 bits (321), Expect = 1e-30
Identities = 84/272 (30%), Positives = 141/272 (51%), Gaps = 17/272 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAP 317
+ Y +++ GN +SLE + +W + + P + D ++LTR GPSG+AP
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDF-GPSGYAP 371
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
V G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 372 VTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 403
>AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 129 bits (312), Expect = 1e-29
Identities = 83/274 (30%), Positives = 140/274 (51%), Gaps = 18/274 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGF 315
+ Y +++ GN +SLE + +W + + P + D ++LTR G G G+
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGY 372
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
APV G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 373 APVTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 406
>AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 129 bits (312), Expect = 1e-29
Identities = 83/274 (30%), Positives = 140/274 (51%), Gaps = 18/274 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 145 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 202
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 203 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 256
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 257 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 312
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGF 315
+ Y +++ GN +SLE + +W + + P + D ++LTR G G G+
Sbjct: 313 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGY 372
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
APV G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 373 APVTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 406
>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
Length = 1159
Score = 129 bits (312), Expect = 1e-29
Identities = 83/274 (30%), Positives = 140/274 (51%), Gaps = 18/274 (6%)
Query: 82 RSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT--QEKHVLRR 139
R P +EC +TG V G+AV ++ CDG L GL++ +F ++P QEK R
Sbjct: 78 RQPLRQEC-VYTGGVTGMPGAAVAISNCDG-LAGLIRTDSTDFFIEPLERGQQEKEASGR 135
Query: 140 RDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRP 199
V + + + V + D ++++ H +P
Sbjct: 136 THVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGD-TERKRRH-----AKP 189
Query: 200 ASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLF 259
S +E+ +V D+++++FHG+E V++Y+L LMNIV I++D SLG +I + + +L
Sbjct: 190 GS----YSIEVLLVVDDSVVRFHGKEHVQNYVLTLMNIVDEIYHDESLGVHINIALVRLI 245
Query: 260 L--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--GPSGF 315
+ Y +++ GN +SLE + +W + + P + D ++LTR G G G+
Sbjct: 246 MVGYRQSLSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHHDHVVFLTRQDFGPSGMQGY 305
Query: 316 APVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
APV G+C RS A++ ++G +SAFVIAHE H+
Sbjct: 306 APVTGMCHPLRSCALNHEDGFSSAFVIAHETGHV 339
>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
protein.
Length = 1211
Score = 116 bits (280), Expect = 9e-26
Identities = 80/259 (30%), Positives = 135/259 (52%), Gaps = 20/259 (7%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTR---TQEKHVLRRRDVTHSERSAEYNLTGD 156
E S+V ++ CDG L GL+++ EEF ++P ++ R V + L G
Sbjct: 166 EASSVALSNCDG-LAGLIRMEEEEFFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGP 224
Query: 157 TVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADN 216
+ V H++ S + RR A+ +E+ + D+
Sbjct: 225 QALDTGASLDSLDSLSRALGVLEEHANSSRRRA-------RRHAAD-DDYNIEVLLGVDD 276
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFL--YEDKDIILKYGNIK 274
++++FHG+E V+ Y+L LMNIV+ I++D SLG++I +V+ ++ L Y +++ GN
Sbjct: 277 SVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLSYGKSMSLIEIGNPS 336
Query: 275 KSLEAINKWNYRHLMKLPE-GSTGW-DATIWLTRSQLG--GPSGFAPVGGVCTKTRSAAI 330
+SLE + +W Y L + P+ G + D I+LTR G G G+APV G+C RS +
Sbjct: 337 QSLENVCRWAY--LQQKPDTGHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTL 394
Query: 331 DRDEGLTSAFVIAHELAHL 349
+ ++G +SAFV+AHE H+
Sbjct: 395 NHEDGFSSAFVVAHETGHV 413
>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
Length = 1205
Score = 116 bits (279), Expect = 1e-25
Identities = 77/278 (27%), Positives = 141/278 (50%), Gaps = 27/278 (9%)
Query: 84 PYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT-----QEK---H 135
P C + G ++ G++V ++ CDG L G+++ EE+ ++P +EK H
Sbjct: 141 PLQTNCAY-VGDIVDIPGTSVAISNCDG-LAGMIKSDNEEYFIEPLERGKQMEEEKGRIH 198
Query: 136 VLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHL 195
V+ +R A +++ D ++H + ++ +
Sbjct: 199 VVYKRSAVEQ---APIDMSKDFHYRESDLEGLDDLGTVYGNIHQQLNET----------M 245
Query: 196 FRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI 255
RR +G +E+ + D+++++FHG+E V++Y+L LMNIV+ I++D SLG +I +V+
Sbjct: 246 RRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVL 305
Query: 256 NKLFL--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--G 311
++ + Y +++ GN +SLE + +W + S D I+LTR G G
Sbjct: 306 VRMIMLGYAKSISLIERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAG 365
Query: 312 PSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G+APV G+C RS ++ ++G +SAFV+AHE H+
Sbjct: 366 MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHV 403
>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 3 protein.
Length = 1205
Score = 116 bits (279), Expect = 1e-25
Identities = 77/278 (27%), Positives = 141/278 (50%), Gaps = 27/278 (9%)
Query: 84 PYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT-----QEK---H 135
P C + G ++ G++V ++ CDG L G+++ EE+ ++P +EK H
Sbjct: 141 PLQTNCAY-VGDIVDIPGTSVAISNCDG-LAGMIKSDNEEYFIEPLERGKQMEEEKGRIH 198
Query: 136 VLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHL 195
V+ +R A +++ D ++H + ++ +
Sbjct: 199 VVYKRSAVEQ---APIDMSKDFHYRESDLEGLDDLGTVYGNIHQQLNET----------M 245
Query: 196 FRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI 255
RR +G +E+ + D+++++FHG+E V++Y+L LMNIV+ I++D SLG +I +V+
Sbjct: 246 RRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVL 305
Query: 256 NKLFL--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--G 311
++ + Y +++ GN +SLE + +W + S D I+LTR G G
Sbjct: 306 VRMIMLGYAKSISLIERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAG 365
Query: 312 PSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G+APV G+C RS ++ ++G +SAFV+AHE H+
Sbjct: 366 MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHV 403
>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
Length = 1201
Score = 116 bits (279), Expect = 1e-25
Identities = 77/278 (27%), Positives = 141/278 (50%), Gaps = 27/278 (9%)
Query: 84 PYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRT-----QEK---H 135
P C + G ++ G++V ++ CDG L G+++ EE+ ++P +EK H
Sbjct: 137 PLQTNCAY-VGDIVDIPGTSVAISNCDG-LAGMIKSDNEEYFIEPLERGKQMEEEKGRIH 194
Query: 136 VLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHL 195
V+ +R A +++ D ++H + ++ +
Sbjct: 195 VVYKRSAVEQ---APIDMSKDFHYRESDLEGLDDLGTVYGNIHQQLNET----------M 241
Query: 196 FRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI 255
RR +G +E+ + D+++++FHG+E V++Y+L LMNIV+ I++D SLG +I +V+
Sbjct: 242 RRRRHAGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVL 301
Query: 256 NKLFL--YEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLG--G 311
++ + Y +++ GN +SLE + +W + S D I+LTR G G
Sbjct: 302 VRMIMLGYAKSISLIERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAG 361
Query: 312 PSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G+APV G+C RS ++ ++G +SAFV+AHE H+
Sbjct: 362 MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHV 399
>AB209497-1|BAD92734.1| 527|Homo sapiens a disintegrin and
metalloprotease with thrombospondin motifs-7
preproprotein va protein.
Length = 527
Score = 106 bits (254), Expect = 1e-22
Identities = 77/260 (29%), Positives = 122/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 105 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 163
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + PR ++ + L R V K W+E +VAD
Sbjct: 164 ----SAPSTCGVQVYP--ELEPRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 217
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 218 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADN 277
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 278 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 337
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 338 SINEDTGLPLAFTVAHELGH 357
>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
protein.
Length = 1077
Score = 103 bits (247), Expect = 9e-22
Identities = 59/157 (37%), Positives = 90/157 (57%), Gaps = 15/157 (9%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY-EDKD 265
++E +VAD M+ +HGR V+ Y+LA+MNIV+ +F D SLGS + +++ +L L ED+
Sbjct: 214 YVETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQP 273
Query: 266 IILKYGNIKKSLEAINKW-----NYR-HLMKLPE-GSTGWDATIWLTRSQL-------GG 311
+ + KSL++ KW N+ H +PE G D + +TR + G
Sbjct: 274 TLEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCG 333
Query: 312 PSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G APVGG+C + RS +++ D GL AF IAHE+ H
Sbjct: 334 TLGLAPVGGMCERERSCSVNEDIGLPQAFTIAHEIGH 370
>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 7 protein.
Length = 1686
Score = 103 bits (246), Expect = 1e-21
Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 140 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 198
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + R ++ + L R V K W+E +VAD
Sbjct: 199 ----SAPSTCGVQVYP--ELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 252
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILK-YGNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 253 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKIMHHADN 312
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 313 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 372
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 373 SINEDTGLPLAFTVAHELGH 392
>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
Length = 1686
Score = 103 bits (246), Expect = 1e-21
Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 140 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 198
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + R ++ + L R V K W+E +VAD
Sbjct: 199 ----SAPSTCGVQVYP--ELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 252
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 253 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADN 312
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 313 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 372
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 373 SINEDTGLPLAFTVAHELGH 392
>AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease
ADAMTS7 protein.
Length = 997
Score = 103 bits (246), Expect = 1e-21
Identities = 76/260 (29%), Positives = 121/260 (46%), Gaps = 18/260 (6%)
Query: 100 EGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLT--GDT 157
EG ++ CDG L G+ Q+ E++ ++P + + +R A L GD+
Sbjct: 140 EGGLAAISACDG-LKGVFQLSNEDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDS 198
Query: 158 VIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGV-KGLWLELAIVADN 216
P + R ++ + L R V K W+E +VAD
Sbjct: 199 ----SAPSTCGVQVYP--ELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADA 252
Query: 217 TMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY-GNIKK 275
M+++HG+ +V+ Y+L +MN+V+ +F+DPS+G+ I + I +L L ED++ LK +
Sbjct: 253 KMVEYHGQPQVESYVLTIMNMVAGLFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADN 312
Query: 276 SLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-------GFAPVGGVCTKTRSA 328
+L++ KW MK D I LTR L G + V G+C RS
Sbjct: 313 TLKSFCKWQKSINMKGDAHPLHHDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSC 372
Query: 329 AIDRDEGLTSAFVIAHELAH 348
+I+ D GL AF +AHEL H
Sbjct: 373 SINEDTGLPLAFTVAHELGH 392
>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
Length = 1509
Score = 97.5 bits (232), Expect = 6e-20
Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 10/162 (6%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLV 254
L RR S K W+E +VAD M+++HG E V+ YIL +MN+V+ +F++PS+G+ I +V
Sbjct: 237 LSRRSIS--KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIV 294
Query: 255 INKLFLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---- 309
+ +L L E+++ LK + +K+L + KW K D + LTR +
Sbjct: 295 VVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGF 354
Query: 310 GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
P G + + G+C RS I+ D GL AF IAHEL H
Sbjct: 355 NRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGH 396
>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 1593
Score = 97.5 bits (232), Expect = 6e-20
Identities = 59/162 (36%), Positives = 89/162 (54%), Gaps = 10/162 (6%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLV 254
L RR S K W+E +VAD M+++HG E V+ YIL +MN+V+ +F++PS+G+ I +V
Sbjct: 237 LSRRSIS--KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIV 294
Query: 255 INKLFLYEDKDIILK-YGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL---- 309
+ +L L E+++ LK + +K+L + KW K D + LTR +
Sbjct: 295 VVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGF 354
Query: 310 GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
P G + + G+C RS I+ D GL AF IAHEL H
Sbjct: 355 NRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGH 396
>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
metalloproteinase with thrombospondin repeats protein.
Length = 1072
Score = 95.1 bits (226), Expect = 3e-19
Identities = 55/150 (36%), Positives = 89/150 (59%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDKD 265
++E+ +VADN M+ +HG E ++HYIL LM+IV++I+ DPS+G+ I +VI N + ++ ++D
Sbjct: 294 FVEVLVVADNRMVSYHG-ENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNEQD 352
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N + +L+ + +W +H P G D + LTR + G A +G
Sbjct: 353 GPSISFNAQTTLKNLCQW--QHSKNSP-GGIHHDTAVLLTRQDICRAHDKCDTLGLAELG 409
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS +I D GL++AF IAHEL H+
Sbjct: 410 TICDPYRSCSISEDSGLSTAFTIAHELGHV 439
>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
Length = 1117
Score = 94.7 bits (225), Expect = 4e-19
Identities = 79/301 (26%), Positives = 141/301 (46%), Gaps = 39/301 (12%)
Query: 76 KENKAIRSPYYKECQFFTGRVLHEEGSA-VTVTECDGQLYGLLQVGGEEFVLQPTR--TQ 132
K+ + + C + TG + + + V ++ C G L+G++ EE+ ++P + T+
Sbjct: 118 KDGPQWKHDFLDNCHY-TGYLQDQRSTTKVALSNCVG-LHGVIATEDEEYFIEPLKNTTE 175
Query: 133 EK----------HVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHS 182
+ HV+ ++ +++ G + SH P ++
Sbjct: 176 DSKHFSYENGHPHVIYKKSALQQRHLYDHSHCGVSDFTRSGKPWWLNDTSTVSHSLPINN 235
Query: 183 DHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIF 242
H H H +R S + ++E +VAD M+ +HGR+ ++HYIL++MNIV+ ++
Sbjct: 236 TH-----IH--HRQKRSVSIER--FVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLY 286
Query: 243 NDPSLGSNITLVINKLF-LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGST----- 296
D SLG+ + +++ +L L ED+ + + KSL++ KW L +G+T
Sbjct: 287 RDSSLGNVVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENG 346
Query: 297 --GWDATIWLTRSQL-------GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELA 347
D + +TR + G G A V G+C RS +I+ D GL SAF IAHE+
Sbjct: 347 IAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIG 406
Query: 348 H 348
H
Sbjct: 407 H 407
>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 9 protein.
Length = 1935
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDKD 265
++E+ +VADN M+ +HG E ++HYIL LM+IV++I+ DPS+G+ I +VI N + ++ ++D
Sbjct: 294 FVEVLVVADNRMVSYHG-ENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNEQD 352
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N + +L+ +W +H P G D + LTR + G A +G
Sbjct: 353 GPSISFNAQTTLKNFCQW--QHSKNSP-GGIHHDTAVLLTRQDICRAHDKCDTLGLAELG 409
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS +I D GL++AF IAHEL H+
Sbjct: 410 TICDPYRSCSISEDSGLSTAFTIAHELGHV 439
>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 9B
protein.
Length = 1935
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDKD 265
++E+ +VADN M+ +HG E ++HYIL LM+IV++I+ DPS+G+ I +VI N + ++ ++D
Sbjct: 294 FVEVLVVADNRMVSYHG-ENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNEQD 352
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N + +L+ +W +H P G D + LTR + G A +G
Sbjct: 353 GPSISFNAQTTLKNFCQW--QHSKNSP-GGIHHDTAVLLTRQDICRAHDKCDTLGLAELG 409
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS +I D GL++AF IAHEL H+
Sbjct: 410 TICDPYRSCSISEDSGLSTAFTIAHELGHV 439
>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
Length = 1471
Score = 94.3 bits (224), Expect = 6e-19
Identities = 55/150 (36%), Positives = 88/150 (58%), Gaps = 11/150 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVI-NKLFLYEDKD 265
++E+ +VADN M+ +HG E ++HYIL LM+IV++I+ DPS+G+ I +VI N + ++ ++D
Sbjct: 136 FVEVLVVADNRMVSYHG-ENLQHYILTLMSIVASIYKDPSIGNLINIVIVNLIVIHNEQD 194
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPVG 319
N + +L+ +W +H P G D + LTR + G A +G
Sbjct: 195 GPSISFNAQTTLKNFCQW--QHSKNSP-GGIHHDTAVLLTRQDICRAHDKCDTLGLAELG 251
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS +I D GL++AF IAHEL H+
Sbjct: 252 TICDPYRSCSISEDSGLSTAFTIAHELGHV 281
>AY692425-1|AAW47398.1| 468|Homo sapiens ADAMTS6 variant 3 protein.
Length = 468
Score = 93.5 bits (222), Expect = 1e-18
Identities = 58/174 (33%), Positives = 94/174 (54%), Gaps = 16/174 (9%)
Query: 191 HDMHLFRRPASGVK-GLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS 249
++ H+ R V ++E +VAD M+ +HGR+ ++HYIL++MNIV+ ++ D SLG+
Sbjct: 234 NNTHIHHRQKRSVSIERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN 293
Query: 250 NITLVINKLF-LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGST-------GWDAT 301
+ +++ +L L ED+ + + KSL++ KW L +G+T D
Sbjct: 294 VVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNA 353
Query: 302 IWLTRSQL-------GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ +TR + G G A V G+C RS +I+ D GL SAF IAHE+ H
Sbjct: 354 VLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGH 407
>AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease
ADAMTS6 protein.
Length = 860
Score = 93.5 bits (222), Expect = 1e-18
Identities = 58/174 (33%), Positives = 94/174 (54%), Gaps = 16/174 (9%)
Query: 191 HDMHLFRRPASGVK-GLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGS 249
++ H+ R V ++E +VAD M+ +HGR+ ++HYIL++MNIV+ ++ D SLG+
Sbjct: 234 NNTHIHHRQKRSVSIERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLGN 293
Query: 250 NITLVINKLF-LYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGST-------GWDAT 301
+ +++ +L L ED+ + + KSL++ KW L +G+T D
Sbjct: 294 VVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNA 353
Query: 302 IWLTRSQL-------GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ +TR + G G A V G+C RS +I+ D GL SAF IAHE+ H
Sbjct: 354 VLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIVH 407
>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 18 protein.
Length = 1221
Score = 93.1 bits (221), Expect = 1e-18
Identities = 57/159 (35%), Positives = 86/159 (54%), Gaps = 9/159 (5%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
R KGL +E +VAD M++ HG+ V YIL +MN+VS +F D ++GS+I +V+
Sbjct: 284 RSAGKSQKGLNVETLVVADKKMVEKHGKGNVTTYILTVMNMVSGLFKDGTIGSDINVVVV 343
Query: 257 KLFLYE-DKDIILKYGNIKKSLEAINKWNYRHLMKLPEGS------TGWDATIWLTRSQL 309
L L E + +L + +SL + +W + K + TG+D W +++
Sbjct: 344 SLILLEQEPGGLLINHHADQSLNSFCQWQSALIGKNGKRHDHAILLTGFDICSW--KNEP 401
Query: 310 GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GFAP+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 402 CDTLGFAPISGMCSKYRSCTINEDTGLGLAFTIAHESGH 440
>BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 91.9 bits (218), Expect = 3e-18
Identities = 54/159 (33%), Positives = 88/159 (55%), Gaps = 7/159 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD +M + +GR ++HY+L L +I + +++ S+ ++I L +
Sbjct: 258 RRRRSISRARQVELLLVADASMARLYGRG-LQHYLLTLASIANRLYSHASIENHIRLAVV 316
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-- 313
K+ + DKD L+ N +L+ KW ++H + +DA I TR L G
Sbjct: 317 KVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSC 376
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C+ RS A+ D+GL +AF +AHE+ HL
Sbjct: 377 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHL 415
>BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 91.9 bits (218), Expect = 3e-18
Identities = 54/159 (33%), Positives = 88/159 (55%), Gaps = 7/159 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD +M + +GR ++HY+L L +I + +++ S+ ++I L +
Sbjct: 258 RRRRSISRARQVELLLVADASMARLYGRG-LQHYLLTLASIANRLYSHASIENHIRLAVV 316
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-- 313
K+ + DKD L+ N +L+ KW ++H + +DA I TR L G
Sbjct: 317 KVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSC 376
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C+ RS A+ D+GL +AF +AHE+ HL
Sbjct: 377 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHL 415
>AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein.
Length = 930
Score = 91.9 bits (218), Expect = 3e-18
Identities = 54/159 (33%), Positives = 88/159 (55%), Gaps = 7/159 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD +M + +GR ++HY+L L +I + +++ S+ ++I L +
Sbjct: 258 RRRRSISRARQVELLLVADASMARLYGRG-LQHYLLTLASIANRLYSHASIENHIRLAVV 316
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-- 313
K+ + DKD L+ N +L+ KW ++H + +DA I TR L G
Sbjct: 317 KVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSC 376
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G A VG +C+ RS A+ D+GL +AF +AHE+ HL
Sbjct: 377 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHL 415
>BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 15 protein.
Length = 950
Score = 89.4 bits (212), Expect = 2e-17
Identities = 75/269 (27%), Positives = 114/269 (42%), Gaps = 14/269 (5%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDV-TH--SER 147
F++G V E S V+ C G L G G E+V+ P +R H R
Sbjct: 102 FYSGDVNAEPDSFAAVSLCGG-LRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRR 160
Query: 148 SAEYNLTGD-TVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGL 206
+GD T PR + + +R S +
Sbjct: 161 GVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPR-- 218
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M+KFHG + ++HY+L L+ + ++ PS+ + I +V+ K+ L D+D
Sbjct: 219 YVETLVVADESMVKFHGAD-LEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDS 277
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
K GN +L W + + WD I TR L G + G A VG
Sbjct: 278 GPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGT 337
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS ++ D+GL SAF AHEL H+
Sbjct: 338 MCDPKRSCSVIEDDGLPSAFTTAHELGHV 366
>AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease
disintegrin 15 with thrombospondin domains protein.
Length = 950
Score = 89.4 bits (212), Expect = 2e-17
Identities = 75/269 (27%), Positives = 114/269 (42%), Gaps = 14/269 (5%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDV-TH--SER 147
F++G V E S V+ C G L G G E+V+ P +R H R
Sbjct: 102 FYSGDVNAEPDSFAAVSLCGG-LRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRR 160
Query: 148 SAEYNLTGD-TVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGL 206
+GD T PR + + +R S +
Sbjct: 161 GVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPR-- 218
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M+KFHG + ++HY+L L+ + ++ PS+ + I +V+ K+ L D+D
Sbjct: 219 YVETLVVADESMVKFHGAD-LEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDS 277
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
K GN +L W + + WD I TR L G + G A VG
Sbjct: 278 GPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGT 337
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C RS ++ D+GL SAF AHEL H+
Sbjct: 338 MCDPKRSCSVIEDDGLPSAFTTAHELGHV 366
>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif 17 protein.
Length = 1095
Score = 88.6 bits (210), Expect = 3e-17
Identities = 83/305 (27%), Positives = 133/305 (43%), Gaps = 33/305 (10%)
Query: 66 LRLLGWDLKLKE-NKAIRSPYYKECQFFTGRVLHEEGSAVTVTECD--GQLYGLLQVGGE 122
LR L +++E A R E F++GRVL GS V+++ C G L GL+Q+G E
Sbjct: 100 LRFLSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQE 159
Query: 123 EFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHS 182
+ ++QP + R + + S + + + PT
Sbjct: 160 QVLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTW------- 212
Query: 183 DHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIF 242
+++ + R + +E +VAD M+++HG E + +IL +MN+V +F
Sbjct: 213 GRPSRDWRERRNAIRLTSEHT----VETLVVADADMVQYHGAEAAQRFILTVMNMVYNMF 268
Query: 243 NDPSLGSNITLVINKLFLYEDKDIILKYGNI-KKSLEAINKW--------NYRHLMKLPE 293
SLG I + + KL L + L G+ ++SLE+ W Y ++P
Sbjct: 269 QHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPG 328
Query: 294 GSTG---WDATIWLTRSQL----GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIA 343
G DA +++TR+ P G A +GGVC+ R + D GL AF IA
Sbjct: 329 GKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIA 388
Query: 344 HELAH 348
HEL H
Sbjct: 389 HELGH 393
>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease
disintegrin 17, with thrombospondin domains protein.
Length = 1095
Score = 88.6 bits (210), Expect = 3e-17
Identities = 83/305 (27%), Positives = 133/305 (43%), Gaps = 33/305 (10%)
Query: 66 LRLLGWDLKLKE-NKAIRSPYYKECQFFTGRVLHEEGSAVTVTECD--GQLYGLLQVGGE 122
LR L +++E A R E F++GRVL GS V+++ C G L GL+Q+G E
Sbjct: 100 LRFLSRGFEVEEAGAARRRGRPAELCFYSGRVLGHPGSLVSLSACGAAGGLVGLIQLGQE 159
Query: 123 EFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHS 182
+ ++QP + R + + S + + + PT
Sbjct: 160 QVLIQPLNNSQGPFSGREHLIRRKWSLTPSPSAEAQRPEQLCKVLTEKKKPTW------- 212
Query: 183 DHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIF 242
+++ + R + +E +VAD M+++HG E + +IL +MN+V +F
Sbjct: 213 GRPSRDWRERRNAIRLTSEHT----VETLVVADADMVQYHGAEAAQRFILTVMNMVYNMF 268
Query: 243 NDPSLGSNITLVINKLFLYEDKDIILKYGNI-KKSLEAINKW--------NYRHLMKLPE 293
SLG I + + KL L + L G+ ++SLE+ W Y ++P
Sbjct: 269 QHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERSLESFCHWQNEEYGGARYLGNNQVPG 328
Query: 294 GSTG---WDATIWLTRSQL----GGPS---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIA 343
G DA +++TR+ P G A +GGVC+ R + D GL AF IA
Sbjct: 329 GKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNLAFTIA 388
Query: 344 HELAH 348
HEL H
Sbjct: 389 HELGH 393
>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
Length = 1207
Score = 88.2 bits (209), Expect = 4e-17
Identities = 75/277 (27%), Positives = 114/277 (41%), Gaps = 30/277 (10%)
Query: 91 FFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAE 150
F+TG VL GS + + C G L G +Q+ + ++P V +RS E
Sbjct: 221 FYTGAVLRHPGSLASFSTCGGGLMGFIQLNEDFIFIEPLNDTMAITGHPHRVYRQKRSME 280
Query: 151 YNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLEL 210
+T + + P S K Y + + + +E
Sbjct: 281 EKVTEKSALHSHYCGIISDKGRPRSRKIAESG--RGKRYSYKLP---------QEYNIET 329
Query: 211 AIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKY 270
+VAD M+ +HG + + +IL ++N+V +F SLG + L + KL L + L
Sbjct: 330 VVVADPAMVSYHGADAARRFILTILNMVFNLFQHKSLGVQVNLRVIKLILLHETPPELYI 389
Query: 271 GNI-KKSLEAINKWNYRHLMKLP----EGSTGW-------DATIWLTRSQL----GGPS- 313
G+ +K LE+ KW + K E ST W DA I +TR P
Sbjct: 390 GHHGEKMLESFCKWQHEEFGKKNDIHLEMSTNWGEDMTSVDAAILITRKDFCVHKDEPCD 449
Query: 314 --GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G A + G+C++ R I D GL AF IAHE+ H
Sbjct: 450 TVGIAYLSGMCSEKRKCIIAEDNGLNLAFTIAHEMGH 486
>DQ266047-1|ABB70405.1| 570|Homo sapiens ADAMTS16s alternative
splice form protein.
Length = 570
Score = 87.0 bits (206), Expect = 9e-17
Identities = 51/151 (33%), Positives = 83/151 (54%), Gaps = 15/151 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD-- 265
+E +V D M++ HG E + Y+L ++N+VSA+F D ++G NI + I L L ED+
Sbjct: 292 VETLVVVDKKMMQNHGHENITTYVLTILNMVSALFKDGTIGGNINIAIVGLILLEDEQPG 351
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGS--------TGWDATIWLTRSQLGGPSGFAP 317
+++ + + +L + +W + K +G+ TG D W +++ GFAP
Sbjct: 352 LVISH-HADHTLSSFCQWQSGLMGK--DGTRHDHAILLTGLDICSW--KNEPCDTLGFAP 406
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 407 ISGMCSKYRSCTINEDTGLGLAFTIAHESGH 437
>AP001698-1|BAA95504.1| 412|Homo sapiens disintegrin-like and
metalloprotease with thrombospondin type 1 motif, 5
protein.
Length = 412
Score = 87.0 bits (206), Expect = 9e-17
Identities = 52/156 (33%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
RR S + +EL +VAD +M + +GR ++HY+L L +I + +++ S+ ++I L +
Sbjct: 258 RRRRSISRARQVELLLVADASMARLYGRG-LQHYLLTLASIANRLYSHASIENHIRLAVV 316
Query: 257 KLFLYEDKDIILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-- 313
K+ + DKD L+ N +L+ KW ++H + +DA I TR L G
Sbjct: 317 KVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYDAAILFTREDLCGHHSC 376
Query: 314 ---GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHEL 346
G A VG +C+ RS A+ D+GL +AF +AHE+
Sbjct: 377 DTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEI 412
>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease
disintegrin 16 with thrombospondin type I motif protein.
Length = 1072
Score = 87.0 bits (206), Expect = 9e-17
Identities = 51/151 (33%), Positives = 83/151 (54%), Gaps = 15/151 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD-- 265
+E +V D M++ HG E + Y+L ++N+VSA+F D ++G NI + I L L ED+
Sbjct: 292 VETLVVVDKKMMQNHGHENITTYVLTILNMVSALFKDGTIGGNINIAIVGLILLEDEQPG 351
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGS--------TGWDATIWLTRSQLGGPSGFAP 317
+++ + + +L + +W + K +G+ TG D W +++ GFAP
Sbjct: 352 LVISH-HADHTLSSFCQWQSGLMGK--DGTRHDHAILLTGLDICSW--KNEPCDTLGFAP 406
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 407 ISGMCSKYRSCTINEDTGLGLAFTIAHESGH 437
>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
Length = 1021
Score = 87.0 bits (206), Expect = 9e-17
Identities = 51/151 (33%), Positives = 83/151 (54%), Gaps = 15/151 (9%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKD-- 265
+E +V D M++ HG E + Y+L ++N+VSA+F D ++G NI + I L L ED+
Sbjct: 89 VETLVVVDKKMMQNHGHENITTYVLTILNMVSALFKDGTIGGNINIAIVGLILLEDEQPG 148
Query: 266 IILKYGNIKKSLEAINKWNYRHLMKLPEGS--------TGWDATIWLTRSQLGGPSGFAP 317
+++ + + +L + +W + K +G+ TG D W +++ GFAP
Sbjct: 149 LVISH-HADHTLSSFCQWQSGLMGK--DGTRHDHAILLTGLDICSW--KNEPCDTLGFAP 203
Query: 318 VGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+ G+C+K RS I+ D GL AF IAHE H
Sbjct: 204 ISGMCSKYRSCTINEDTGLGLAFTIAHESGH 234
>BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 1 protein.
Length = 967
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 259 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 317
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 318 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 377
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 378 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 406
>AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with
thrombospondin type 1 motifs protein.
Length = 967
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 259 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 317
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 318 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 377
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 378 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 406
>AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease
protein.
Length = 967
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 259 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 317
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 318 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 377
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 378 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 406
>AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with
thrombospondin type 1 motifs ADAMTS1 protein.
Length = 967
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 259 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 317
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 318 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 377
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 378 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 406
>AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein.
Length = 950
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 242 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 300
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 301 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 360
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 361 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 389
>AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein.
Length = 999
Score = 85.8 bits (203), Expect = 2e-16
Identities = 47/149 (31%), Positives = 79/149 (53%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 291 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 349
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ N +L W +H + +D I TR L G G A VG
Sbjct: 350 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCGSQTCDTLGMADVGT 409
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC +RS ++ D+GL +AF AHEL H+
Sbjct: 410 VCDPSRSCSVIEDDGLQAAFTTAHELGHV 438
>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
Length = 1081
Score = 84.6 bits (200), Expect = 5e-16
Identities = 56/159 (35%), Positives = 83/159 (52%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVIN 256
R KGL +E +VAD M++ HG+ V YIL +M VS +F D ++GS+I +V+
Sbjct: 284 RSAGKSQKGLNVETLVVADKKMVEKHGKGNVTTYILTVMK-VSGLFKDGTIGSDINVVVV 342
Query: 257 KLFLYEDKDI-ILKYGNIKKSLEAINKWNYRHLMKLPEGS------TGWDATIWLTRSQL 309
L L E + +L + +SL + +W + K + TG+D W +++
Sbjct: 343 SLILLEQEPGGLLINHHADQSLNSFCQWQSALIGKNGKRHDHAILLTGFDICSW--KNEP 400
Query: 310 GGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GFAP G+C+K RS I+ D GL AF IAHE H
Sbjct: 401 CDTLGFAPTSGMCSKYRSCTINEDTGLGLAFTIAHESGH 439
>AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein.
Length = 837
Score = 77.0 bits (181), Expect = 9e-14
Identities = 50/149 (33%), Positives = 74/149 (49%), Gaps = 7/149 (4%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS-----GFAPVGG 320
+ G + ++L + W G +D I TR L G S G A VG
Sbjct: 278 GPQVGPSAAQTLRSFCAWQRGLNTPEDSGPDHFDTAILFTRQDLCGVSTCDTLGMADVGT 337
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
VC RS AI D+GL SAF AHEL H+
Sbjct: 338 VCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 76.6 bits (180), Expect = 1e-13
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPENSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 335
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 336 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein.
Length = 837
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 335
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 336 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 335
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 336 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein.
Length = 837
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 335
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 336 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 366
>AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein.
Length = 849
Score = 76.2 bits (179), Expect = 2e-13
Identities = 52/151 (34%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 231 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 289
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTG--WDATIWLTRSQLGGPS-----GFAPV 318
+ G + ++L + W + + PE S +D I TR L G S G A V
Sbjct: 290 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTRQDLCGVSTCDTLGMADV 347
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
G VC RS AI D+GL SAF AHEL H+
Sbjct: 348 GTVCDPARSCAIVEDDGLQSAFTAAHELGHV 378
>BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein.
Length = 918
Score = 72.5 bits (170), Expect = 2e-12
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M F+G + ++++IL LM++ + I+ PS+ ++I L++ K+ + ED+
Sbjct: 249 FVETLLVADASMAAFYGAD-LQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKW 307
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF------APVG 319
+ N +L W R +D I LTR G G A +G
Sbjct: 308 GPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIG 367
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ DEGL +A +AHEL H+
Sbjct: 368 TICDPNKSCSVIEDEGLQAAHTLAHELGHV 397
>AF175283-1|AAF25806.1| 246|Homo sapiens zinc metalloendopeptidase
protein.
Length = 246
Score = 72.5 bits (170), Expect = 2e-12
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M F+G + ++++IL LM++ + I+ PS+ ++I L++ K+ + ED+
Sbjct: 27 FVETLLVADASMAAFYGAD-LQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKW 85
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF------APVG 319
+ N +L W R +D I LTR G G A +G
Sbjct: 86 GPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIG 145
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ DEGL +A +AHEL H+
Sbjct: 146 TICDPNKSCSVIEDEGLQAAHTLAHELGHV 175
>AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein.
Length = 890
Score = 72.5 bits (170), Expect = 2e-12
Identities = 44/150 (29%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M F+G + ++++IL LM++ + I+ PS+ ++I L++ K+ + ED+
Sbjct: 221 FVETLLVADASMAAFYGAD-LQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKW 279
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF------APVG 319
+ N +L W R +D I LTR G G A +G
Sbjct: 280 GPEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIG 339
Query: 320 GVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ DEGL +A +AHEL H+
Sbjct: 340 TICDPNKSCSVIEDEGLQAAHTLAHELGHV 369
>BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein.
Length = 676
Score = 70.1 bits (164), Expect = 1e-11
Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 8/149 (5%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
L L VAD +M F+G + ++++IL LM++ + I+ PS+ ++I L++ K+ + ED+
Sbjct: 8 LFLERVADASMAAFYGAD-LQNHILTLMSVAARIYKHPSIKNSINLMVVKVLIVEDEKWG 66
Query: 268 LKYG-NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF------APVGG 320
+ N +L W R +D I LTR G G A +G
Sbjct: 67 PEVSDNGGLTLRNFCNWQRRFNQPSDRHPEHYDTAILLTRQNFCGQEGLCDTLGVADIGT 126
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+C +S ++ DEGL +A +AHEL H+
Sbjct: 127 ICDPNKSCSVIEDEGLQAAHTLAHELGHV 155
>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 20
protein.
Length = 1911
Score = 69.3 bits (162), Expect = 2e-11
Identities = 43/150 (28%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY--EDK 264
++E+ + AD ++ HG +++YIL LM+IV+ I+ DPS+G+ I +V+ KL + E++
Sbjct: 260 YIEIMVTADAKVVSAHG-SNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEE 318
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPV 318
++ + +L+ W + D + +TR + G + +
Sbjct: 319 GPVINFDG-ATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITREDICSSKEKCNTLGLSYL 377
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G +C +S I+ ++GL SAF IAHEL H
Sbjct: 378 GTICDPLQSCFINEEKGLISAFTIAHELGH 407
>AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 847
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/126 (34%), Positives = 68/126 (53%), Gaps = 15/126 (11%)
Query: 238 VSAIFNDPSLGSNITLVINKLFLY-EDKDIILKYGNIKKSLEAINKW-----NYR-HLMK 290
V+ +F D SLGS + +++ +L L ED+ + + KSL++ KW N+ H
Sbjct: 25 VAKLFQDSSLGSTVNILVTRLILLTEDQPTLEITHHAGKSLDSFCKWQKSIVNHSGHGNA 84
Query: 291 LPE-GSTGWDATIWLTRSQLG-------GPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVI 342
+PE G D + +TR + G G APVGG+C + RS +++ D GL +AF I
Sbjct: 85 IPENGVANHDTAVLITRYDICIYKNKPCGTLGLAPVGGMCERERSCSVNEDIGLATAFTI 144
Query: 343 AHELAH 348
AHE+ H
Sbjct: 145 AHEIGH 150
>AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ16363 fis, clone THYMU2031139, weakly similar
to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
mRNA. ).
Length = 502
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/150 (32%), Positives = 73/150 (48%), Gaps = 19/150 (12%)
Query: 218 MLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNI-KKS 276
M+++HG E + +IL +MN+V +F SLG I + + KL L + L G+ ++S
Sbjct: 1 MVQYHGAEAAQRFILTVMNMVYNMFQHQSLGIKINIQVTKLVLLRQRPAKLSIGHHGERS 60
Query: 277 LEAINKW--------NYRHLMKLPEGSTG---WDATIWLTRSQL----GGPS---GFAPV 318
LE+ W Y ++P G DA +++TR+ P G A +
Sbjct: 61 LESFCHWQNEEYGGARYLGNNQVPGGKDDPPLVDAAVFVTRTDFCVHKDEPCDTVGIAYL 120
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
GGVC+ R + D GL AF IAHEL H
Sbjct: 121 GGVCSAKRKCVLAEDNGLNLAFTIAHELGH 150
>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
Length = 1502
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/150 (28%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY--EDK 264
++E+ + AD ++ HG +++YIL LM+IV+ I+ DPS+G+ I +V+ KL + E++
Sbjct: 260 YIEIMVTADAKVVSAHG-SNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEE 318
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPV 318
++ + +L+ W + D + +TR + G + +
Sbjct: 319 GPVINFDG-ATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITRYDICSSKEKCNMLGLSYL 377
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G +C +S I+ ++GL SAF IAHEL H
Sbjct: 378 GTICDPLQSCFINEEKGLISAFTIAHELGH 407
>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
Length = 1908
Score = 68.5 bits (160), Expect = 3e-11
Identities = 43/150 (28%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLY--EDK 264
++E+ + AD ++ HG +++YIL LM+IV+ I+ DPS+G+ I +V+ KL + E++
Sbjct: 260 YIEIMVTADAKVVSAHG-SNLQNYILTLMSIVATIYKDPSIGNLIHIVVVKLVMIHREEE 318
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS------GFAPV 318
++ + +L+ W + D + +TR + G + +
Sbjct: 319 GPVINFDG-ATTLKNFCSWQQTQNDLDDVHPSHHDTAVLITRYDICSSKEKCNMLGLSYL 377
Query: 319 GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G +C +S I+ ++GL SAF IAHEL H
Sbjct: 378 GTICDPLQSCFINEEKGLISAFTIAHELGH 407
>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>BC103829-1|AAI03830.1| 276|Homo sapiens ADAMTS13 protein protein.
Length = 276
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>BC103828-1|AAI03829.1| 276|Homo sapiens ADAMTS13 protein protein.
Length = 276
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
factor-cleaving protease precursor protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase
with thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AJ420811-1|CAD12730.1| 344|Homo sapiens ADAMTS-13 protein,
truncated variant protein.
Length = 344
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant
2 protein.
Length = 1371
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
Length = 1340
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
factor-cleaving protease protein.
Length = 1427
Score = 58.4 bits (135), Expect = 3e-08
Identities = 45/159 (28%), Positives = 71/159 (44%), Gaps = 10/159 (6%)
Query: 197 RRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITL-VI 255
RR A G+ L LEL + + + H +E + Y+L +NI + + DPSLG+ + ++
Sbjct: 73 RRAAGGI--LHLELLVAVGPDVFQAH-QEDTERYVLTNLNIGAELLRDPSLGAQFRVHLV 129
Query: 256 NKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGF 315
+ L E + N+ SL ++ W+ + D +++TR L P G
Sbjct: 130 KMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDLELPDGN 189
Query: 316 APV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
V GG C+ T S I D G IAHE+ H
Sbjct: 190 RQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 228
>AK129873-1|BAC85245.1| 226|Homo sapiens protein ( Homo sapiens
cDNA FLJ26363 fis, clone HRT05360, highly similar to
ADAM-TS 1 PRECURSOR (EC 3.4.24.-). ).
Length = 226
Score = 55.2 bits (127), Expect = 3e-07
Identities = 29/106 (27%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD +M +FHG +KHY+L L ++ + ++ PS+ ++++LV+ K+ + D+
Sbjct: 21 YVETMLVADQSMAEFHG-SGLKHYLLTLFSVAARLYKHPSIRNSVSLVVVKILVIHDEQK 79
Query: 267 ILKY-GNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGG 311
+ N +L W +H + +D I TR L G
Sbjct: 80 GPEVTSNAALTLRNFCNWQKQHNPPSDRDAEHYDTAILFTRQDLCG 125
>AF215824-1|AAG43987.1| 754|Homo sapiens a disintegrin and
metalloproteinase 7 protein.
Length = 754
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/155 (28%), Positives = 82/155 (52%), Gaps = 16/155 (10%)
Query: 201 SGVKGL----WLELAIVADNTMLKFHG--RERVKHYILALMNIVSAIFNDPSLGSNITLV 254
S +KG+ ++EL IVAD+T+ + +G ++++ I ++N V+ I+ +L ++TLV
Sbjct: 190 SKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYK--TLNIHVTLV 247
Query: 255 INKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL-GGPS 313
+++ +EDK I Y NI+ +L + W K+ + +D + L+ L
Sbjct: 248 GIEIWTHEDK--IELYSNIETTLLRFSFWQ----EKILKTRKDFDHVVLLSGKWLYSHVQ 301
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + GG+C S +I +D L +IA+ +AH
Sbjct: 302 GISYPGGMCLPYYSTSIIKDL-LPDTNIIANRMAH 335
Score = 36.3 bits (80), Expect = 0.16
Identities = 14/60 (23%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 75 LKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEK 134
+K R P + F+ G ++HE SA +++ C+G L G ++ + ++++P + ++
Sbjct: 92 MKGGAFTRHPQIMDHCFYQGSIVHEYDSAASISTCNG-LRGFFRINDQRYLIEPVKYSDE 150
>AF090327-1|AAC36742.1| 588|Homo sapiens sperm maturation-related
glycoprotein GP-83 protein.
Length = 588
Score = 48.0 bits (109), Expect = 5e-05
Identities = 44/155 (28%), Positives = 82/155 (52%), Gaps = 16/155 (10%)
Query: 201 SGVKGL----WLELAIVADNTMLKFHG--RERVKHYILALMNIVSAIFNDPSLGSNITLV 254
S +KG+ ++EL IVAD+T+ + +G ++++ I ++N V+ I+ +L ++TLV
Sbjct: 24 SKIKGIHDEKYVELFIVADDTVYRRNGHPHNKLRNRIWGMVNFVNMIYK--TLNIHVTLV 81
Query: 255 INKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQL-GGPS 313
+++ +EDK I Y NI+ +L + W K+ + +D + L+ L
Sbjct: 82 GIEIWTHEDK--IELYSNIETTLLRFSFWQ----EKILKTRKDFDHVVLLSGKWLYSHVQ 135
Query: 314 GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
G + GG+C S +I +D L +IA+ +AH
Sbjct: 136 GISYPGGMCLPYYSTSIIKDL-LPDTNIIANRMAH 169
>BC060804-1|AAH60804.1| 737|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 737
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 212 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 267
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 268 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 324
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 325 DQSGGIVMDHSDNPLGAAVTLAHELGH 351
>AY692426-1|AAW47399.1| 292|Homo sapiens ADAMTS6 variant 4 protein.
Length = 292
Score = 42.3 bits (95), Expect = 0.002
Identities = 19/49 (38%), Positives = 32/49 (65%), Gaps = 1/49 (2%)
Query: 191 HDMHLFRRPASGVK-GLWLELAIVADNTMLKFHGRERVKHYILALMNIV 238
++ H+ R V ++E +VAD M+ +HGR+ ++HYIL++MNIV
Sbjct: 234 NNTHIHHRQKRSVSIERFVETLVVADKMMVGYHGRKDIEHYILSVMNIV 282
>AY358878-1|AAQ89237.1| 735|Homo sapiens ADAM-12 protein.
Length = 735
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 212 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 267
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 268 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 324
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 325 DQSGGIVMDHSDNPLGAAVTLAHELGH 351
>AL589787-6|CAI40683.1| 738|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 738
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 215 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 270
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 271 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 327
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 328 DQSGGIVMDHSDNPLGAAVTLAHELGH 354
>AL589787-5|CAI40682.1| 909|Homo sapiens ADAM metallopeptidase
domain 12 (meltrin alpha) protein.
Length = 909
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 215 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 270
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 271 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 327
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 328 DQSGGIVMDHSDNPLGAAVTLAHELGH 354
>AF023477-1|AAC08703.2| 738|Homo sapiens meltrin-S protein.
Length = 738
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 215 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 270
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 271 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 327
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 328 DQSGGIVMDHSDNPLGAAVTLAHELGH 354
>AF023476-1|AAC08702.2| 909|Homo sapiens meltrin-L precursor
protein.
Length = 909
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/147 (28%), Positives = 65/147 (44%), Gaps = 12/147 (8%)
Query: 207 WLELAIVADNTMLKFHGR--ERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++EL IVADN + G+ E+VK ++ + N V + NI +V+ + ++ D
Sbjct: 215 YVELVIVADNREFQRQGKDLEKVKQRLIEIANHVDKFYRP----LNIRIVLVGVEVWNDM 270
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D + SL W R + LP S +A + G G AP+ +CT
Sbjct: 271 DKCSVSQDPFTSLHEFLDW--RKMKLLPRKSHD-NAQLVSGVYFQGTTIGMAPIMSMCTA 327
Query: 325 TRSAAI---DRDEGLTSAFVIAHELAH 348
+S I D L +A +AHEL H
Sbjct: 328 DQSGGIVMDHSDNPLGAAVTLAHELGH 354
>BC030812-1|AAH30812.1| 339|Homo sapiens ADAMTS4 protein protein.
Length = 339
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGS--TGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ G + ++L + W + + PE S +D I TR Q+ S AP CT
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTR-QVRPQS--APQAMHCT 332
Query: 324 KTRSA 328
RSA
Sbjct: 333 ILRSA 337
>AL590714-7|CAH72147.1| 339|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 339
Score = 41.9 bits (94), Expect = 0.003
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 9/125 (7%)
Query: 207 WLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI 266
++E +VAD+ M FHG +K Y+L +M + F PS+ + ++LV+ +L + +
Sbjct: 219 FVETLVVADDKMAAFHGAG-LKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEE 277
Query: 267 ILKYG-NIKKSLEAINKWNYRHLMKLPEGS--TGWDATIWLTRSQLGGPSGFAPVGGVCT 323
+ G + ++L + W + + PE S +D I TR Q+ S AP CT
Sbjct: 278 GPQVGPSAAQTLRSFCAW--QRGLNTPEDSDPDHFDTAILFTR-QVRPQS--APQAMHCT 332
Query: 324 KTRSA 328
RSA
Sbjct: 333 ILRSA 337
>U41766-1|AAC50403.1| 819|Homo sapiens
metalloprotease/disintegrin/cysteine-rich protein
precursor protein.
Length = 819
Score = 40.7 bits (91), Expect = 0.007
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR A + ++EL IV D GR + V+ ++ L N + +++ + NI
Sbjct: 201 LRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMY----IMLNIR 256
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+V+ L ++ + ++I G L +W + L+ D+ + + GG
Sbjct: 257 IVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH----DSAQLVLKKGFGGT 312
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGL---TSAFVIAHELAH 348
+G A VG VC+++ + I+ + T A ++AHEL H
Sbjct: 313 AGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGH 351
>D14665-1|BAA03499.2| 703|Homo sapiens KIAA0021 protein protein.
Length = 703
Score = 40.7 bits (91), Expect = 0.007
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR A + ++EL IV D GR + V+ ++ L N + +++ + NI
Sbjct: 85 LRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMY----IMLNIR 140
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+V+ L ++ + ++I G L +W + L+ D+ + + GG
Sbjct: 141 IVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH----DSAQLVLKKGFGGT 196
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGL---TSAFVIAHELAH 348
+G A VG VC+++ + I+ + T A ++AHEL H
Sbjct: 197 AGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGH 235
>BC126406-1|AAI26407.1| 712|Homo sapiens ADAM9 protein protein.
Length = 712
Score = 40.7 bits (91), Expect = 0.007
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR A + ++EL IV D GR + V+ ++ L N + +++ + NI
Sbjct: 201 LRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMY----IMLNIR 256
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+V+ L ++ + ++I G L +W + L+ D+ + + GG
Sbjct: 257 IVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH----DSAQLVLKKGFGGT 312
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGL---TSAFVIAHELAH 348
+G A VG VC+++ + I+ + T A ++AHEL H
Sbjct: 313 AGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGH 351
>AF495383-1|AAM49575.1| 655|Homo sapiens
disintegrin/metalloproteinase domain 9 short protein
precursor protein.
Length = 655
Score = 40.7 bits (91), Expect = 0.007
Identities = 40/159 (25%), Positives = 74/159 (46%), Gaps = 13/159 (8%)
Query: 195 LFRRPASGVKGLWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNIT 252
L RR A + ++EL IV D GR + V+ ++ L N + +++ + NI
Sbjct: 201 LRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMY----IMLNIR 256
Query: 253 LVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGP 312
+V+ L ++ + ++I G L +W + L+ D+ + + GG
Sbjct: 257 IVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH----DSAQLVLKKGFGGT 312
Query: 313 SGFAPVGGVCTKTRSAAIDRDEGL---TSAFVIAHELAH 348
+G A VG VC+++ + I+ + T A ++AHEL H
Sbjct: 313 AGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGH 351
>DQ995342-1|ABI97387.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AY358314-1|AAQ88680.1| 813|Homo sapiens Adam33 protein.
Length = 813
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AL356755-2|CAI23465.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AL356755-1|CAM28348.1| 812|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 812
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AL109804-2|CAI18840.1| 813|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 813
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AL109804-1|CAM26955.1| 812|Homo sapiens ADAM metallopeptidase
domain 33 protein.
Length = 812
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AF466288-1|AAM80483.1| 812|Homo sapiens a disintegrin and
metalloprotease domain 33 protein.
Length = 812
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AF466287-1|AAM80482.1| 812|Homo sapiens a disintegrin and
metalloprotease domain 33 protein.
Length = 812
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>AB055891-1|BAB83092.1| 813|Homo sapiens metalloprotease
disintegrin protein.
Length = 813
Score = 39.9 bits (89), Expect = 0.013
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 207 WLELAIVADNTMLKFHGRE--RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IVAD+T+ R K +L + N V + +L + L +++ D+
Sbjct: 211 YLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLR--TLDIQVALTGLEVWTERDR 268
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
+ + N +L A +W + P S A + R+ G G APV G+C
Sbjct: 269 SRVTQDANA--TLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRA 322
Query: 325 TRSAAIDRDEG---LTSAFVIAHELAH 348
S + D + +A +AHE+ H
Sbjct: 323 ESSGGVSTDHSELPIGAAATMAHEIGH 349
>BC058037-1|AAH58037.1| 210|Homo sapiens ADAM7 protein protein.
Length = 210
Score = 36.3 bits (80), Expect = 0.16
Identities = 14/60 (23%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 75 LKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEK 134
+K R P + F+ G ++HE SA +++ C+G L G ++ + ++++P + ++
Sbjct: 92 MKGEAFTRHPQIMDHCFYQGSIVHEYDSAASISTCNG-LRGFFRINDQRYLIEPVKYSDE 150
>BC034975-1|AAH34975.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>BC030698-1|AAH30698.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>BC030014-1|AAH30014.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>BC028702-1|AAH28702.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>BC026169-1|AAH26169.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>BC026085-1|AAH26085.1| 787|Homo sapiens ADAM metallopeptidase
domain 32 protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>AY358739-1|AAQ89099.1| 787|Homo sapiens similar to MDC family
protein.
Length = 787
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>AY172952-1|AAO45696.1| 629|Homo sapiens metalloproteinase 12-like
protein protein.
Length = 629
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 186 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 241
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 242 ENKISTVGEADELLQKFLEWKQSYLNLRP 270
>AB209690-1|BAD92927.1| 279|Homo sapiens ADAM 32 precursor (A
disintegrin and metalloprotease domain 32) variant
protein.
Length = 279
Score = 36.3 bits (80), Expect = 0.16
Identities = 21/89 (23%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 206 LWLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYED 263
L+LE+ IV D T+ + G + V + ++ ++ + +++F +T+V++ L L+ D
Sbjct: 187 LYLEMHIVVDKTLYDYWGSDSMIVTNKVIEIVGLANSMFTQ----FKVTIVLSSLELWSD 242
Query: 264 KDIILKYGNIKKSLEAINKWNYRHLMKLP 292
++ I G + L+ +W +L P
Sbjct: 243 ENKISTVGEADELLQKFLEWKQSYLNLRP 271
>AY532929-1|AAS54901.1| 90|Homo sapiens von Willebrand
factor-cleaving protease protein.
Length = 90
Score = 34.3 bits (75), Expect = 0.65
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 6/56 (10%)
Query: 299 DATIWLTRSQLGGPSGFAPV------GGVCTKTRSAAIDRDEGLTSAFVIAHELAH 348
D +++TR L P G V GG C+ T S I D G IAHE+ H
Sbjct: 35 DLVLYITRFDLELPDGNRQVRVVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGH 90
>BC126253-1|AAI26254.1| 512|Homo sapiens ADAM10 protein protein.
Length = 512
Score = 33.5 bits (73), Expect = 1.1
Identities = 54/275 (19%), Positives = 107/275 (38%), Gaps = 27/275 (9%)
Query: 86 YKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPT------RTQEKH--VL 137
Y +TG + EEGS + DG+ G +Q G F ++P RT H +
Sbjct: 97 YDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIY 156
Query: 138 RRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFR 197
D+ + + D + + + + E +
Sbjct: 157 HEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRK----K 212
Query: 198 RPASGVKGLWLELAIVADNTMLKFHG-RERVKHYILALMNIVSAIFNDPSLGS--NITLV 254
R S K +L I D+ K++G RE V I + + + I+ NI+ +
Sbjct: 213 RTTSAEKNT-CQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFM 271
Query: 255 INKLFL---YEDKDII--LKYGNI--KKSLEAINKWNY-RHLMKLPEGSTGWDATIWLTR 306
+ ++ + ++KD ++ NI +K LE ++ N+ + + +D + L
Sbjct: 272 VKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGV-LGL 330
Query: 307 SQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFV 341
+ +G PSG + GG+C K++ + + + L + +
Sbjct: 331 AWVGAPSGSS--GGICEKSKLYSDGKKKSLNTGII 363
>AF009615-1|AAC51766.1| 748|Homo sapiens ADAM10 protein.
Length = 748
Score = 33.5 bits (73), Expect = 1.1
Identities = 54/275 (19%), Positives = 107/275 (38%), Gaps = 27/275 (9%)
Query: 86 YKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPT------RTQEKH--VL 137
Y +TG + EEGS + DG+ G +Q G F ++P RT H +
Sbjct: 97 YDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYIKDRTLPFHSVIY 156
Query: 138 RRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRHSDHSDKEYFHDMHLFR 197
D+ + + D + + + + E +
Sbjct: 157 HEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRK----K 212
Query: 198 RPASGVKGLWLELAIVADNTMLKFHG-RERVKHYILALMNIVSAIFNDPSLGS--NITLV 254
R S K +L I D+ K++G RE V I + + + I+ NI+ +
Sbjct: 213 RTTSAEKNT-CQLYIQTDHLFFKYYGTREAVIAQISSHVKAIDTIYQTTDFSGIRNISFM 271
Query: 255 INKLFL---YEDKDII--LKYGNI--KKSLEAINKWNY-RHLMKLPEGSTGWDATIWLTR 306
+ ++ + ++KD ++ NI +K LE ++ N+ + + +D + L
Sbjct: 272 VKRIRINTTADEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGV-LGL 330
Query: 307 SQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFV 341
+ +G PSG + GG+C K++ + + + L + +
Sbjct: 331 AWVGAPSGSS--GGICEKSKLYSDGKKKSLNTGII 363
>X99374-1|CAA67753.1| 735|Homo sapiens fertilin beta protein.
Length = 735
Score = 32.7 bits (71), Expect = 2.0
Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 207 WLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++E+ ++ + + G + V + L+ + +AIF + NIT++++ L L+ D+
Sbjct: 179 YIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAIF----VSFNITIILSSLELWIDE 234
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLP 292
+ I G + L +W +L+ P
Sbjct: 235 NKIATTGEANELLHTFLRWKTSYLVLRP 262
>U52370-1|AAC51110.1| 735|Homo sapiens fertilin beta protein.
Length = 735
Score = 32.7 bits (71), Expect = 2.0
Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 207 WLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++E+ ++ + + G + V + L+ + +AIF + NIT++++ L L+ D+
Sbjct: 179 YIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAIF----VSFNITIILSSLELWIDE 234
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLP 292
+ I G + L +W +L+ P
Sbjct: 235 NKIATTGEANELLHTFLRWKTSYLVLRP 262
>U38805-1|AAD04206.1| 734|Homo sapiens fertilin beta protein.
Length = 734
Score = 32.7 bits (71), Expect = 2.0
Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 207 WLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++E+ ++ + + G + V + L+ + +AIF + NIT++++ L L+ D+
Sbjct: 178 YIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAIF----VSFNITIILSSLELWIDE 233
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLP 292
+ I G + L +W +L+ P
Sbjct: 234 NKIATTGEANELLHTFLRWKTSYLVLRP 261
>AJ133005-1|CAB40813.1| 735|Homo sapiens fertilin beta protein
protein.
Length = 735
Score = 32.7 bits (71), Expect = 2.0
Identities = 19/88 (21%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 207 WLELAIVADNTMLKFHGRER--VKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
++E+ ++ + + G + V + L+ + +AIF + NIT++++ L L+ D+
Sbjct: 179 YIEMHVIVEKQLYNHMGSDTTVVAQKVFQLIGLTNAIF----VSFNITIILSSLELWIDE 234
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLP 292
+ I G + L +W +L+ P
Sbjct: 235 NKIATTGEANELLHTFLRWKTSYLVLRP 262
>BC035515-1|AAH35515.1| 324|Homo sapiens chromosome 5 open reading
frame 36 protein.
Length = 324
Score = 31.5 bits (68), Expect = 4.6
Identities = 13/27 (48%), Positives = 18/27 (66%)
Query: 258 LFLYEDKDIILKYGNIKKSLEAINKWN 284
LFLY + ++I+KY NI+ L A WN
Sbjct: 200 LFLYPESEVIIKYQNIQNKLLANLLWN 226
>BC132765-1|AAI32766.1| 832|Homo sapiens ADAM metallopeptidase
domain 23 protein.
Length = 832
Score = 30.7 bits (66), Expect = 8.0
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 207 WLELAIVADNTMLKFH--GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IV D+ K H ++ +++N+V +I+ + L + + LV + + +K
Sbjct: 300 YLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKE-QLNTRVVLVAVET--WTEK 356
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I N + L +K+ R T RS L S F GGVC++
Sbjct: 357 DQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSL---SYF---GGVCSR 410
Query: 325 TRSAAIDRDEGLTSAF--VIAHELA 347
TR ++ + GL A V++ LA
Sbjct: 411 TRGVGVN-EYGLPMAVAQVLSQSLA 434
>BC132763-1|AAI32764.1| 832|Homo sapiens ADAM metallopeptidase
domain 23 protein.
Length = 832
Score = 30.7 bits (66), Expect = 8.0
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 207 WLELAIVADNTMLKFH--GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IV D+ K H ++ +++N+V +I+ + L + + LV + + +K
Sbjct: 300 YLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKE-QLNTRVVLVAVET--WTEK 356
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I N + L +K+ R T RS L S F GGVC++
Sbjct: 357 DQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSL---SYF---GGVCSR 410
Query: 325 TRSAAIDRDEGLTSAF--VIAHELA 347
TR ++ + GL A V++ LA
Sbjct: 411 TRGVGVN-EYGLPMAVAQVLSQSLA 434
>AJ005580-1|CAC20565.1| 832|Homo sapiens Adam23 protein protein.
Length = 832
Score = 30.7 bits (66), Expect = 8.0
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 207 WLELAIVADNTMLKFH--GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IV D+ K H ++ +++N+V +I+ + L + + LV + + +K
Sbjct: 300 YLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKE-QLNTRVVLVAVET--WTEK 356
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I N + L +K+ R T RS L S F GGVC++
Sbjct: 357 DQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSL---SYF---GGVCSR 410
Query: 325 TRSAAIDRDEGLTSAF--VIAHELA 347
TR ++ + GL A V++ LA
Sbjct: 411 TRGVGVN-EYGLPMAVAQVLSQSLA 434
>AC009225-1|AAX93195.1| 579|Homo sapiens unknown protein.
Length = 579
Score = 30.7 bits (66), Expect = 8.0
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 207 WLELAIVADNTMLKFH--GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IV D+ K H ++ +++N+V +I+ + L + + LV + + +K
Sbjct: 300 YLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKE-QLNTRVVLVAVET--WTEK 356
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I N + L +K+ R T RS L S F GGVC++
Sbjct: 357 DQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSL---SYF---GGVCSR 410
Query: 325 TRSAAIDRDEGLTSAF--VIAHELA 347
TR ++ + GL A V++ LA
Sbjct: 411 TRGVGVN-EYGLPMAVAQVLSQSLA 434
>AB009672-1|BAA32351.1| 832|Homo sapiens MDC3 protein.
Length = 832
Score = 30.7 bits (66), Expect = 8.0
Identities = 39/145 (26%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Query: 207 WLELAIVADNTMLKFH--GRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDK 264
+LEL IV D+ K H ++ +++N+V +I+ + L + + LV + + +K
Sbjct: 300 YLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVDSIYKE-QLNTRVVLVAVET--WTEK 356
Query: 265 DIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTK 324
D I N + L +K+ R T RS L S F GGVC++
Sbjct: 357 DQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRVTFHYKRSSL---SYF---GGVCSR 410
Query: 325 TRSAAIDRDEGLTSAF--VIAHELA 347
TR ++ + GL A V++ LA
Sbjct: 411 TRGVGVN-EYGLPMAVAQVLSQSLA 434
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 46,359,566
Number of Sequences: 224733
Number of extensions: 1699744
Number of successful extensions: 2854
Number of sequences better than 10.0: 123
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2610
Number of HSP's gapped (non-prelim): 143
length of query: 349
length of database: 73,234,838
effective HSP length: 91
effective length of query: 258
effective length of database: 52,784,135
effective search space: 13618306830
effective search space used: 13618306830
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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