Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002474-TA|BGIBMGA002474-PA|IPR001590|Peptidase M12B,
ADAM/reprolysin
(349 letters)
Database: fruitfly
52,641 sequences; 24,830,863 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY119538-1|AAM50192.1| 769|Drosophila melanogaster GH22104p pro... 80 4e-15
AE014298-778|AAF46065.2| 1059|Drosophila melanogaster CG4096-PA ... 80 4e-15
AY094716-1|AAM11069.1| 1688|Drosophila melanogaster GH16393p pro... 72 1e-12
AE014297-2048|AAF55199.3| 1537|Drosophila melanogaster CG14869-P... 72 1e-12
AE014297-2047|AAS65157.1| 1688|Drosophila melanogaster CG14869-P... 72 1e-12
AE013599-3473|AAF46905.1| 1091|Drosophila melanogaster CG3622-PB... 52 2e-06
AY089340-1|AAL90078.1| 790|Drosophila melanogaster AT15733p pro... 50 5e-06
AE013599-3474|AAM71125.1| 790|Drosophila melanogaster CG3622-PA... 50 5e-06
AY118344-1|AAM48373.1| 476|Drosophila melanogaster LP02257p pro... 33 0.77
AE013599-3684|AAZ93569.1| 476|Drosophila melanogaster CG9850-PB... 33 0.77
AE013599-3683|AAF47059.2| 639|Drosophila melanogaster CG9850-PA... 33 0.77
>AY119538-1|AAM50192.1| 769|Drosophila melanogaster GH22104p
protein.
Length = 769
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/148 (30%), Positives = 80/148 (54%), Gaps = 9/148 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E IVAD TM FH + Y+L +MN+VSA++ DPS+G++I +V+ ++ ++++
Sbjct: 315 VETLIVADATMSAFH--RDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQ 372
Query: 268 LKYG---NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGG 320
L+ N +K+L+ W ++ + D I +TR + + G A VGG
Sbjct: 373 LQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGG 432
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+C +S +++ D G+ + I HEL H
Sbjct: 433 MCKPKQSCSVNEDNGIMLSHTITHELGH 460
Score = 33.1 bits (72), Expect = 0.58
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 60 AQETHHLRLLGWDLKLKENKAI---------RSPY---YKECQFFTGRVLHEEGSAVTVT 107
A ET HL L+ L N + RSP + C F G+V + + V ++
Sbjct: 100 ANETLHLELMAHSYFLAPNLVVERHRRDLRTRSPLTTRHLNCHFH-GKVRGQPATNVAIS 158
Query: 108 ECDGQLYGLLQVGGEEFVLQPTRTQEKH 135
C G L G ++ G E+ ++P++ E H
Sbjct: 159 TCAG-LVGHIRTAGNEYFIEPSKEHEPH 185
>AE014298-778|AAF46065.2| 1059|Drosophila melanogaster CG4096-PA
protein.
Length = 1059
Score = 80.2 bits (189), Expect = 4e-15
Identities = 45/148 (30%), Positives = 80/148 (54%), Gaps = 9/148 (6%)
Query: 208 LELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDII 267
+E IVAD TM FH + Y+L +MN+VSA++ DPS+G++I +V+ ++ ++++
Sbjct: 332 VETLIVADATMSAFH--RDLNGYLLTIMNMVSALYKDPSIGNSIEIVVVRIIQLDEEESQ 389
Query: 268 LKYG---NIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPS----GFAPVGG 320
L+ N +K+L+ W ++ + D I +TR + + G A VGG
Sbjct: 390 LQLNLTQNAQKNLDRFCSWQHKLNKGSEKDPHHHDVAILITRKNICANNCMTLGLANVGG 449
Query: 321 VCTKTRSAAIDRDEGLTSAFVIAHELAH 348
+C +S +++ D G+ + I HEL H
Sbjct: 450 MCKPKQSCSVNEDNGIMLSHTITHELGH 477
>AY094716-1|AAM11069.1| 1688|Drosophila melanogaster GH16393p
protein.
Length = 1688
Score = 71.7 bits (168), Expect = 1e-12
Identities = 79/297 (26%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 65 HLRLL--GWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGE 122
H+R+L G + E +A + C F++G V + S V+V+ C G + G ++
Sbjct: 323 HIRILKEGEEHPGPETEAEAEQRHLGC-FYSGYVEDDPHSMVSVSLCGG-MTGYIKTSFG 380
Query: 123 EFVLQPT-RTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRH 181
++QP RT VL R S+R+A + ++ + R
Sbjct: 381 ALLIQPVNRTSSDEVLHRV-FRKSQRNARHAVSKFELGLDDFMSKLEQVQEEEQKSKSRK 439
Query: 182 SDHSDKEYFH-DMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSA 240
+ + Y D ++ LE+ I DN+M +FHG E ++ YIL LM+IVS+
Sbjct: 440 LNRKKRHYADVDNQVYT----------LEVLIAVDNSMKQFHG-EDLQPYILILMSIVSS 488
Query: 241 IFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDA 300
IF D S+G++I +++ +L + NI + N+ + + D
Sbjct: 489 IFADASIGNSIRILLVRL---------ISLPNINDQTHSSNEMLKHFCQFINQSGYERDT 539
Query: 301 TIWLTRSQLGG--PS------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ +TR + G P G A +G VC+ + S +I +D GL +AF +AHEL H+
Sbjct: 540 AMLITREPICGSVPGKICHMLGLAELGTVCSSS-SCSIVQDTGLPTAFTMAHELGHI 595
>AE014297-2048|AAF55199.3| 1537|Drosophila melanogaster CG14869-PA,
isoform A protein.
Length = 1537
Score = 71.7 bits (168), Expect = 1e-12
Identities = 79/297 (26%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 65 HLRLL--GWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGE 122
H+R+L G + E +A + C F++G V + S V+V+ C G + G ++
Sbjct: 172 HIRILKEGEEHPGPETEAEAEQRHLGC-FYSGYVEDDPHSMVSVSLCGG-MTGYIKTSFG 229
Query: 123 EFVLQPT-RTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRH 181
++QP RT VL R S+R+A + ++ + R
Sbjct: 230 ALLIQPVNRTSSDEVLHRV-FRKSQRNARHAVSKFELGLDDFMSKLEQVQEEEQKSKSRK 288
Query: 182 SDHSDKEYFH-DMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSA 240
+ + Y D ++ LE+ I DN+M +FHG E ++ YIL LM+IVS+
Sbjct: 289 LNRKKRHYADVDNQVYT----------LEVLIAVDNSMKQFHG-EDLQPYILILMSIVSS 337
Query: 241 IFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDA 300
IF D S+G++I +++ +L + NI + N+ + + D
Sbjct: 338 IFADASIGNSIRILLVRL---------ISLPNINDQTHSSNEMLKHFCQFINQSGYERDT 388
Query: 301 TIWLTRSQLGG--PS------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ +TR + G P G A +G VC+ + S +I +D GL +AF +AHEL H+
Sbjct: 389 AMLITREPICGSVPGKICHMLGLAELGTVCSSS-SCSIVQDTGLPTAFTMAHELGHI 444
>AE014297-2047|AAS65157.1| 1688|Drosophila melanogaster CG14869-PB,
isoform B protein.
Length = 1688
Score = 71.7 bits (168), Expect = 1e-12
Identities = 79/297 (26%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 65 HLRLL--GWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGE 122
H+R+L G + E +A + C F++G V + S V+V+ C G + G ++
Sbjct: 323 HIRILKEGEEHPGPETEAEAEQRHLGC-FYSGYVEDDPHSMVSVSLCGG-MTGYIKTSFG 380
Query: 123 EFVLQPT-RTQEKHVLRRRDVTHSERSAEYNLTGDTVIXXXXXXXXXXXXXPTSHVHPRH 181
++QP RT VL R S+R+A + ++ + R
Sbjct: 381 ALLIQPVNRTSSDEVLHRV-FRKSQRNARHAVSKFELGLDDFMSKLEQVQEEEQKSKSRK 439
Query: 182 SDHSDKEYFH-DMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSA 240
+ + Y D ++ LE+ I DN+M +FHG E ++ YIL LM+IVS+
Sbjct: 440 LNRKKRHYADVDNQVYT----------LEVLIAVDNSMKQFHG-EDLQPYILILMSIVSS 488
Query: 241 IFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDA 300
IF D S+G++I +++ +L + NI + N+ + + D
Sbjct: 489 IFADASIGNSIRILLVRL---------ISLPNINDQTHSSNEMLKHFCQFINQSGYERDT 539
Query: 301 TIWLTRSQLGG--PS------GFAPVGGVCTKTRSAAIDRDEGLTSAFVIAHELAHL 349
+ +TR + G P G A +G VC+ + S +I +D GL +AF +AHEL H+
Sbjct: 540 AMLITREPICGSVPGKICHMLGLAELGTVCSSS-SCSIVQDTGLPTAFTMAHELGHI 595
>AE013599-3473|AAF46905.1| 1091|Drosophila melanogaster CG3622-PB,
isoform B protein.
Length = 1091
Score = 51.6 bits (118), Expect = 2e-06
Identities = 48/196 (24%), Positives = 86/196 (43%), Gaps = 28/196 (14%)
Query: 176 HVHP-RHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKF-------HGRERV 227
H HP +H + Y D R + + L++E AI D+ + + +V
Sbjct: 256 HHHPHQHHQQRRRRYIGDAPRSRW-SDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKV 314
Query: 228 KHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI--ILKYGNIKKSLEAINKW-- 283
++LA++N V +++ P+LG I V+ +L +++ D +++ +++ L + KW
Sbjct: 315 VSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQE 374
Query: 284 -----------NYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDR 332
+Y H + L TG D + G A V G+CT S I+
Sbjct: 375 KLNPFSDADPLHYDHALVL----TGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINE 430
Query: 333 DEGLTSAFVIAHELAH 348
+ S FV+AHE+ H
Sbjct: 431 AKHFESVFVVAHEIGH 446
>AY089340-1|AAL90078.1| 790|Drosophila melanogaster AT15733p
protein.
Length = 790
Score = 50.0 bits (114), Expect = 5e-06
Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 19/138 (13%)
Query: 226 RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI--ILKYGNIKKSLEAINKW 283
+V ++LA++N V +++ P+LG I V+ +L +++ D +++ +++ L + KW
Sbjct: 12 KVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKW 71
Query: 284 -------------NYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI 330
+Y H + L TG D + G A V G+CT S I
Sbjct: 72 QEKLNPFSDADPLHYDHALVL----TGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTI 127
Query: 331 DRDEGLTSAFVIAHELAH 348
+ + S FV+AHE+ H
Sbjct: 128 NEAKHFESVFVVAHEIGH 145
>AE013599-3474|AAM71125.1| 790|Drosophila melanogaster CG3622-PA,
isoform A protein.
Length = 790
Score = 50.0 bits (114), Expect = 5e-06
Identities = 36/138 (26%), Positives = 65/138 (47%), Gaps = 19/138 (13%)
Query: 226 RVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDI--ILKYGNIKKSLEAINKW 283
+V ++LA++N V +++ P+LG I V+ +L +++ D +++ +++ L + KW
Sbjct: 12 KVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKW 71
Query: 284 -------------NYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAI 330
+Y H + L TG D + G A V G+CT S I
Sbjct: 72 QEKLNPFSDADPLHYDHALVL----TGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTI 127
Query: 331 DRDEGLTSAFVIAHELAH 348
+ + S FV+AHE+ H
Sbjct: 128 NEAKHFESVFVVAHEIGH 145
>AY118344-1|AAM48373.1| 476|Drosophila melanogaster LP02257p
protein.
Length = 476
Score = 32.7 bits (71), Expect = 0.77
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 7/46 (15%)
Query: 311 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVI-AHELAHL 349
G +GFA VGG C K S AI D G S ++ AHE+ HL
Sbjct: 13 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHL 58
>AE013599-3684|AAZ93569.1| 476|Drosophila melanogaster CG9850-PB,
isoform B protein.
Length = 476
Score = 32.7 bits (71), Expect = 0.77
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 7/46 (15%)
Query: 311 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVI-AHELAHL 349
G +GFA VGG C K S AI D G S ++ AHE+ HL
Sbjct: 13 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHL 58
>AE013599-3683|AAF47059.2| 639|Drosophila melanogaster CG9850-PA,
isoform A protein.
Length = 639
Score = 32.7 bits (71), Expect = 0.77
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 7/46 (15%)
Query: 311 GPSGFAPVGGVCT------KTRSAAIDRDEGLTSAFVI-AHELAHL 349
G +GFA VGG C K S AI D G S ++ AHE+ HL
Sbjct: 434 GTAGFAYVGGACVVNKRLEKVNSVAIIEDTGGFSGIIVAAHEVGHL 479
Database: fruitfly
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 24,830,863
Number of sequences in database: 52,641
Lambda K H
0.320 0.136 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 15,377,193
Number of Sequences: 52641
Number of extensions: 570813
Number of successful extensions: 1097
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1073
Number of HSP's gapped (non-prelim): 13
length of query: 349
length of database: 24,830,863
effective HSP length: 86
effective length of query: 263
effective length of database: 20,303,737
effective search space: 5339882831
effective search space used: 5339882831
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 62 (29.1 bits)
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