Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002457-TA|BGIBMGA002457-PA|IPR002086|Aldehyde
dehydrogenase, IPR012303|NAD-dependent aldehyde dehydrogenase
(486 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P13601 Cluster: Aldehyde dehydrogenase, cytosolic 1; n=... 537 e-151
UniRef50_P30837 Cluster: Aldehyde dehydrogenase X, mitochondrial... 515 e-144
UniRef50_Q56YU0 Cluster: Aldehyde dehydrogenase 2C4, cytosolic; ... 484 e-135
UniRef50_Q29AE2 Cluster: GA15986-PA; n=1; Drosophila pseudoobscu... 481 e-134
UniRef50_P40108 Cluster: Aldehyde dehydrogenase; n=5; cellular o... 460 e-128
UniRef50_P46367 Cluster: Potassium-activated aldehyde dehydrogen... 442 e-122
UniRef50_A2RH33 Cluster: Aldehyde dehydrogenase; n=21; cellular ... 440 e-122
UniRef50_O75891 Cluster: 10-formyltetrahydrofolate dehydrogenase... 433 e-120
UniRef50_Q25417 Cluster: Aldehyde dehydrogenase, mitochondrial p... 425 e-117
UniRef50_Q4TBF9 Cluster: Chromosome undetermined SCAF7131, whole... 422 e-117
UniRef50_Q4SUU7 Cluster: Chromosome undetermined SCAF13842, whol... 418 e-115
UniRef50_Q2UGV3 Cluster: Aldehyde dehydrogenase; n=9; Ascomycota... 416 e-115
UniRef50_A7RQR3 Cluster: Predicted protein; n=1; Nematostella ve... 409 e-112
UniRef50_Q0SCV0 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|R... 403 e-111
UniRef50_O74187 Cluster: Aldehyde dehydrogenase; n=42; cellular ... 403 e-111
UniRef50_Q89NQ8 Cluster: Betaine aldehyde dehydrogenase; n=4; Pr... 402 e-110
UniRef50_Q5KW79 Cluster: NAD-dependent aldehyde dehydrogenase; n... 402 e-110
UniRef50_Q54IU0 Cluster: Aldehyde dehydrogenase; n=1; Dictyostel... 400 e-110
UniRef50_Q39P13 Cluster: Aldehyde dehydrogenase; n=1; Burkholder... 396 e-109
UniRef50_Q9URW9 Cluster: Aldehyde dehydrogenase; n=20; Ascomycot... 394 e-108
UniRef50_Q1AVQ5 Cluster: Betaine-aldehyde dehydrogenase; n=1; Ru... 387 e-106
UniRef50_Q0SDT3 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|R... 386 e-106
UniRef50_Q0FK42 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 384 e-105
UniRef50_Q1LDQ8 Cluster: Aldehyde dehydrogenase; n=3; Burkholder... 384 e-105
UniRef50_A2QV34 Cluster: Similarity to indole-3-acetaldehyde deh... 381 e-104
UniRef50_Q4ZZX2 Cluster: Aldehyde dehydrogenase; n=6; Proteobact... 379 e-104
UniRef50_A0QGB6 Cluster: P-cumic aldehyde dehydrogenase; n=4; My... 378 e-103
UniRef50_Q9RYT8 Cluster: Aldehyde dehydrogenase; n=29; Bacteria|... 378 e-103
UniRef50_O33455 Cluster: P-cumic aldehyde dehydrogenase; n=7; Pr... 376 e-103
UniRef50_Q11AE9 Cluster: Aldehyde dehydrogenase; n=10; Bacteria|... 375 e-102
UniRef50_A5EL04 Cluster: Aldehyde dehydrogenase; n=10; Bacteria|... 375 e-102
UniRef50_A0R5S7 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 373 e-102
UniRef50_P54114 Cluster: Aldehyde dehydrogenase [NAD(P)+] 2; n=8... 373 e-102
UniRef50_Q39MG6 Cluster: Aldehyde dehydrogenase; n=1; Burkholder... 372 e-102
UniRef50_P71016 Cluster: Betaine aldehyde dehydrogenase; n=16; c... 370 e-101
UniRef50_Q5L3J6 Cluster: Aldehyde dehydrogenase; n=6; Bacteria|R... 369 e-101
UniRef50_Q391L7 Cluster: Betaine-aldehyde dehydrogenase; n=12; P... 369 e-101
UniRef50_Q11FB7 Cluster: Aldehyde dehydrogenase; n=5; Proteobact... 368 e-100
UniRef50_A7Q2D6 Cluster: Chromosome chr1 scaffold_46, whole geno... 365 2e-99
UniRef50_Q6W1I3 Cluster: Aldehyde dehydrogenase; n=4; Proteobact... 363 4e-99
UniRef50_UPI00006CDA6E Cluster: aldehyde dehydrogenase; n=2; Tet... 362 1e-98
UniRef50_Q5LLB4 Cluster: Phenylacetaldehyde dehydrogenase; n=58;... 361 3e-98
UniRef50_Q01RS0 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; S... 360 5e-98
UniRef50_Q98H34 Cluster: NADP-dependent aldehyde dehydrogenase; ... 359 9e-98
UniRef50_A1SEY4 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; N... 357 4e-97
UniRef50_Q88K06 Cluster: Aldehyde dehydrogenase family protein; ... 356 6e-97
UniRef50_A2U9B6 Cluster: Aldehyde dehydrogenase; n=8; Bacteria|R... 356 8e-97
UniRef50_A0JW23 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; A... 355 1e-96
UniRef50_Q57EI0 Cluster: Betaine aldehyde dehydrogenase; n=47; B... 355 1e-96
UniRef50_Q0SDC1 Cluster: Aldehyde dehydrogenase; n=10; Actinomyc... 354 3e-96
UniRef50_Q11KV7 Cluster: Aldehyde dehydrogenase; n=13; Proteobac... 353 8e-96
UniRef50_A3Q3X2 Cluster: Aldehyde dehydrogenase; n=11; Bacteria|... 353 8e-96
UniRef50_P23883 Cluster: Gamma-glutamyl-gamma-aminobutyraldehyde... 352 1e-95
UniRef50_Q75TI0 Cluster: Glycine betaine aldehyde dehydrogenase;... 351 2e-95
UniRef50_Q3YAT5 Cluster: Hydroxyisobutyraldehyde dehydrogenase; ... 351 2e-95
UniRef50_Q9L397 Cluster: FldD protein; n=1; Sphingomonas sp. LB1... 351 2e-95
UniRef50_Q5KYB4 Cluster: Aldehyde dehydrogenase; n=8; Bacillacea... 350 6e-95
UniRef50_Q11K71 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 349 7e-95
UniRef50_Q6D6E0 Cluster: Betaine aldehyde dehydrogenase; n=127; ... 348 2e-94
UniRef50_Q0SJZ2 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 348 2e-94
UniRef50_Q0UEE3 Cluster: Putative uncharacterized protein; n=1; ... 348 2e-94
UniRef50_A1D0S9 Cluster: Aldehyde dehydrogenase; n=4; Pezizomyco... 347 5e-94
UniRef50_Q0SFT2 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 345 2e-93
UniRef50_Q0RKA3 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 345 2e-93
UniRef50_A1B0W8 Cluster: Aldehyde dehydrogenase (NAD(+)); n=2; c... 344 4e-93
UniRef50_Q5UWD2 Cluster: Aldehyde dehydrogenase; n=1; Haloarcula... 344 4e-93
UniRef50_Q8EMH4 Cluster: 5-carboxymethyl-2-hydroxymuconate semia... 343 5e-93
UniRef50_Q5SJP9 Cluster: 5-carboxymethyl-2-hydroxymuconate semia... 343 8e-93
UniRef50_Q398R4 Cluster: Betaine-aldehyde dehydrogenase; n=11; B... 343 8e-93
UniRef50_Q0S9W8 Cluster: Aminomuconate-semialdehyde dehydrogenas... 342 1e-92
UniRef50_Q9AH09 Cluster: Putative aldehyde dehydrogenase; n=1; R... 340 6e-92
UniRef50_Q5UWQ5 Cluster: Aldehyde dehydrogenase; n=1; Haloarcula... 340 6e-92
UniRef50_Q39PC1 Cluster: Aldehyde dehydrogenase; n=70; Bacteria|... 338 2e-91
UniRef50_Q1IRN9 Cluster: Aldehyde dehydrogenase; n=15; cellular ... 338 2e-91
UniRef50_A6VY68 Cluster: Aldehyde dehydrogenase; n=36; cellular ... 336 7e-91
UniRef50_A5V831 Cluster: Aldehyde dehydrogenase; n=1; Sphingomon... 335 1e-90
UniRef50_UPI000023F6D5 Cluster: hypothetical protein FG11034.1; ... 333 5e-90
UniRef50_Q48AP9 Cluster: Betaine aldehyde dehydrogenase; n=1; Co... 333 7e-90
UniRef50_Q8TIR3 Cluster: Aldehyde dehydrogenase (NAD(P)+); n=7; ... 333 7e-90
UniRef50_Q0SBJ9 Cluster: Aldehyde dehydrogenase; n=2; Actinomyce... 332 9e-90
UniRef50_A6UK36 Cluster: Aldehyde dehydrogenase; n=2; Sinorhizob... 332 1e-89
UniRef50_A0KE30 Cluster: Aldehyde dehydrogenase; n=6; cellular o... 332 1e-89
UniRef50_Q47943 Cluster: L-sorbosone dehydrogenase, NAD(P) depen... 332 2e-89
UniRef50_A1G8I3 Cluster: Aldehyde dehydrogenase; n=2; Salinispor... 332 2e-89
UniRef50_Q1QBF6 Cluster: Aldehyde dehydrogenase; n=3; Gammaprote... 331 3e-89
UniRef50_Q89NG4 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|R... 330 4e-89
UniRef50_Q7Z1Q3 Cluster: Aldehyde dehydrogenase protein 12, isof... 329 8e-89
UniRef50_Q396X6 Cluster: Aldehyde dehydrogenase; n=18; cellular ... 328 2e-88
UniRef50_P23240 Cluster: Aldehyde dehydrogenase; n=339; Bacteria... 328 2e-88
UniRef50_Q739I7 Cluster: Aldehyde dehydrogenase; n=3; Bacillacea... 326 6e-88
UniRef50_Q5UWQ8 Cluster: Aldehyde dehydrogenase; n=4; Halobacter... 326 8e-88
UniRef50_Q6FBY4 Cluster: Putative aldehyde dehydrogenase; n=1; A... 324 4e-87
UniRef50_P80668 Cluster: Phenylacetaldehyde dehydrogenase; n=23;... 323 6e-87
UniRef50_Q5KVH3 Cluster: 5-carboxy-2-hydroxymuconate semialdehyd... 322 2e-86
UniRef50_Q5QL36 Cluster: Glycine betaine aldehyde dehydrogenase;... 321 3e-86
UniRef50_Q5HLA3 Cluster: Putative aldehyde dehydrogenase aldA; n... 321 3e-86
UniRef50_Q2VLJ6 Cluster: Aldehyde dehydrogenase; n=8; Pezizomyco... 319 9e-86
UniRef50_P49189 Cluster: 4-trimethylaminobutyraldehyde dehydroge... 319 1e-85
UniRef50_UPI000038E2A1 Cluster: hypothetical protein Faci_030001... 318 2e-85
UniRef50_Q2SHE9 Cluster: NAD-dependent aldehyde dehydrogenase; n... 318 2e-85
UniRef50_Q39NZ7 Cluster: Succinic semialdehyde dehydrogenase; n=... 317 4e-85
UniRef50_Q5V606 Cluster: Aldehyde dehydrogenase; n=2; Halobacter... 317 5e-85
UniRef50_A5V6Y8 Cluster: Aldehyde dehydrogenase; n=1; Sphingomon... 316 6e-85
UniRef50_Q39A62 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|R... 316 8e-85
UniRef50_P42329 Cluster: Aldehyde dehydrogenase, thermostable; n... 316 8e-85
UniRef50_Q47PW2 Cluster: Betaine-aldehyde dehydrogenase; n=1; Th... 315 1e-84
UniRef50_Q1LEY1 Cluster: Aldehyde dehydrogenase; n=4; Bacteria|R... 315 1e-84
UniRef50_A1WPM7 Cluster: Betaine-aldehyde dehydrogenase; n=1; Ve... 315 1e-84
UniRef50_Q0U8X3 Cluster: Putative uncharacterized protein; n=2; ... 314 3e-84
UniRef50_Q8YD95 Cluster: ALDEHYDE DEHYDROGENASE; n=75; Bacteria|... 314 3e-84
UniRef50_Q8Y8I9 Cluster: Lmo0913 protein; n=11; Listeria|Rep: Lm... 314 4e-84
UniRef50_O24174 Cluster: Betaine aldehyde dehydrogenase; n=6; Vi... 314 4e-84
UniRef50_Q5FQ94 Cluster: Aldehyde dehydrogenase; n=1; Gluconobac... 313 6e-84
UniRef50_A1RDQ2 Cluster: Aldehyde dehydrogenase; n=4; Actinobact... 313 6e-84
UniRef50_O85973 Cluster: Benzaldehyde dehydrogenase; n=8; Proteo... 312 1e-83
UniRef50_Q11K50 Cluster: Aldehyde dehydrogenase; n=49; cellular ... 312 2e-83
UniRef50_A0QP86 Cluster: Aldehyde dehydrogenase family protein; ... 311 3e-83
UniRef50_Q4J873 Cluster: Aldehyde dehydrogenase; n=4; Thermoprot... 311 3e-83
UniRef50_A3IE80 Cluster: Aldehyde dehydrogenase; n=1; Bacillus s... 310 4e-83
UniRef50_Q39MD0 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 310 6e-83
UniRef50_A3VCB8 Cluster: Aldehyde dehydrogenase family protein; ... 310 6e-83
UniRef50_Q4STS4 Cluster: Chromosome undetermined SCAF14118, whol... 309 1e-82
UniRef50_Q6SF25 Cluster: Aldehyde dehydrogenase family protein; ... 309 1e-82
UniRef50_A1G3Y3 Cluster: Aldehyde dehydrogenase; n=4; Bacteria|R... 309 1e-82
UniRef50_Q39HU8 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 309 1e-82
UniRef50_Q11AU6 Cluster: Aldehyde dehydrogenase; n=22; Bacteria|... 309 1e-82
UniRef50_A3Q4A6 Cluster: Aldehyde dehydrogenase; n=1; Mycobacter... 309 1e-82
UniRef50_Q98LH9 Cluster: Aldehyde dehydrogenase; n=1; Mesorhizob... 308 2e-82
UniRef50_Q02AF5 Cluster: Aldehyde dehydrogenase; n=1; Solibacter... 308 2e-82
UniRef50_P25526 Cluster: Succinate-semialdehyde dehydrogenase [N... 308 2e-82
UniRef50_Q40024 Cluster: Betaine aldehyde dehydrogenase; n=60; M... 308 2e-82
UniRef50_Q0S070 Cluster: Aldehyde dehydrogenase; n=10; Actinomyc... 308 3e-82
UniRef50_Q0RW45 Cluster: Possible aldehyde dehydrogenase; n=3; A... 308 3e-82
UniRef50_Q0ETU5 Cluster: Aldehyde dehydrogenase; n=1; Thermoanae... 307 5e-82
UniRef50_Q395Z7 Cluster: Succinate-semialdehyde dehydrogenase (N... 306 7e-82
UniRef50_Q4J7R8 Cluster: Aldehyde dehydrogenase; n=2; Thermoprot... 306 7e-82
UniRef50_Q9STS1 Cluster: Betaine aldehyde dehydrogenase 2, mitoc... 306 7e-82
UniRef50_A0LTW2 Cluster: Betaine-aldehyde dehydrogenase; n=4; Ba... 305 1e-81
UniRef50_P42269 Cluster: 5-carboxymethyl-2-hydroxymuconate semia... 304 3e-81
UniRef50_Q73RK8 Cluster: Betaine aldehyde dehydrogenase; n=1; Tr... 304 4e-81
UniRef50_A4X8T1 Cluster: Aldehyde dehydrogenase; n=1; Salinispor... 304 4e-81
UniRef50_Q5PMN7 Cluster: Possible aldehyde dehydrogenase; n=16; ... 303 5e-81
UniRef50_A0B664 Cluster: Betaine-aldehyde dehydrogenase; n=1; Me... 303 5e-81
UniRef50_A0IVF9 Cluster: Aldehyde dehydrogenase; n=1; Serratia p... 303 6e-81
UniRef50_A6VRB2 Cluster: Succinic semialdehyde dehydrogenase; n=... 303 8e-81
UniRef50_A4F0G0 Cluster: Aldehyde dehydrogenase family protein; ... 303 8e-81
UniRef50_A6F548 Cluster: Aldehyde dehydrogenase; n=1; Marinobact... 302 1e-80
UniRef50_Q9AH30 Cluster: 2-aminomuconic semialdehyde dehydrogena... 301 2e-80
UniRef50_Q20352 Cluster: Aldehyde dehydrogenase protein 11, isof... 301 2e-80
UniRef50_Q4FMK5 Cluster: Succinate-semialdehyde dehydrogenase (N... 301 3e-80
UniRef50_Q2FM54 Cluster: Aldehyde dehydrogenase; n=1; Methanospi... 301 3e-80
UniRef50_A5UWF0 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|R... 301 3e-80
UniRef50_A4FGR5 Cluster: Betaine-aldehyde dehydrogenase; n=4; Ac... 301 3e-80
UniRef50_Q5B1Z5 Cluster: Putative uncharacterized protein; n=1; ... 301 3e-80
UniRef50_Q12HD9 Cluster: Aldehyde dehydrogenase; n=34; Proteobac... 300 6e-80
UniRef50_Q8CV96 Cluster: Aldehyde dehydrogenase; n=7; cellular o... 299 8e-80
UniRef50_Q26FT5 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|R... 299 1e-79
UniRef50_A0G7A9 Cluster: Aldehyde dehydrogenase; n=8; Bacteria|R... 299 1e-79
UniRef50_O59808 Cluster: Probable betaine aldehyde dehydrogenase... 299 1e-79
UniRef50_Q7QBI1 Cluster: ENSANGP00000016555; n=7; cellular organ... 299 1e-79
UniRef50_A1UC91 Cluster: Betaine-aldehyde dehydrogenase precurso... 298 2e-79
UniRef50_Q9UTM8 Cluster: Succinate-semialdehyde dehydrogenase; n... 297 3e-79
UniRef50_Q97BQ6 Cluster: Betaine aldehyde dehydrogenase; n=2; Th... 297 3e-79
UniRef50_A0W6P7 Cluster: Salicylaldehyde dehydrogenase; n=1; Geo... 297 4e-79
UniRef50_Q6NER7 Cluster: Betaine aldehyde dehydrogenase; n=31; B... 297 6e-79
UniRef50_Q0SDD4 Cluster: Aldehyde dehydrogenase; n=6; Actinomyce... 297 6e-79
UniRef50_Q0SCN9 Cluster: Aldehyde dehydrogenase; n=2; Actinomyce... 296 7e-79
UniRef50_A7UBP5 Cluster: Putative aldehyde dehydrogenase; n=1; P... 296 7e-79
UniRef50_Q3W6C9 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 296 1e-78
UniRef50_A5V7S3 Cluster: Aldehyde dehydrogenase; n=2; Sphingomon... 295 2e-78
UniRef50_Q0CN81 Cluster: Putative uncharacterized protein; n=1; ... 295 2e-78
UniRef50_Q9H2A2 Cluster: Aldehyde dehydrogenase family 8 member ... 294 4e-78
UniRef50_Q4J9S9 Cluster: Aldehyde dehydrogenase; n=1; Sulfolobus... 294 4e-78
UniRef50_Q8BWF0 Cluster: Succinate semialdehyde dehydrogenase, m... 294 4e-78
UniRef50_P51649 Cluster: Succinate semialdehyde dehydrogenase, m... 294 4e-78
UniRef50_Q0SC67 Cluster: Probable aldehyde dehydrogenase; n=1; R... 293 5e-78
UniRef50_A5VCT2 Cluster: Aldehyde dehydrogenase; n=2; Sphingomon... 293 5e-78
UniRef50_Q3K7P7 Cluster: Betaine-aldehyde dehydrogenase; n=9; Pr... 293 7e-78
UniRef50_Q1AV69 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacte... 293 7e-78
UniRef50_A6VZV8 Cluster: Aldehyde dehydrogenase; n=20; Proteobac... 293 9e-78
UniRef50_Q2J3W1 Cluster: Betaine-aldehyde dehydrogenase; n=7; Pr... 292 1e-77
UniRef50_O86001 Cluster: Salicylaldehyde dehydrogenase; n=2; Nov... 292 1e-77
UniRef50_Q1GJB8 Cluster: Aldehyde dehydrogenase; n=10; Proteobac... 291 2e-77
UniRef50_Q9US47 Cluster: Succinate-semialdehyde dehydrogenase; n... 291 2e-77
UniRef50_A6C3Q3 Cluster: Aldehyde dehydrogenase; n=1; Planctomyc... 291 4e-77
UniRef50_Q6CK88 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 289 8e-77
UniRef50_P23105 Cluster: 2-hydroxymuconic semialdehyde dehydroge... 289 8e-77
UniRef50_Q1AYL0 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacte... 289 1e-76
UniRef50_Q0I8D9 Cluster: Aldehyde dehydrogenase family protein; ... 289 1e-76
UniRef50_Q9RBF6 Cluster: Succinate semialdehyde dehydrogenase; n... 289 1e-76
UniRef50_A3U0D4 Cluster: 5-carboxymethyl-2-hydroxymuconate semia... 289 1e-76
UniRef50_Q0CFZ9 Cluster: Putative uncharacterized protein; n=1; ... 288 2e-76
UniRef50_P38067 Cluster: Succinate-semialdehyde dehydrogenase [N... 288 2e-76
UniRef50_Q29491 Cluster: Aldehyde dehydrogenase, cytosolic 2; n=... 288 2e-76
UniRef50_UPI000023D4C2 Cluster: hypothetical protein FG11482.1; ... 287 3e-76
UniRef50_Q18822 Cluster: Aldehyde dehydrogenase protein 10; n=2;... 287 3e-76
UniRef50_Q0S0U5 Cluster: Aldehyde dehydrogenase; n=3; Actinomyce... 287 4e-76
UniRef50_Q92VA3 Cluster: Putatively membrane-anchored aldehyde d... 286 1e-75
UniRef50_A0JWG2 Cluster: Aldehyde dehydrogenase; n=4; Actinomyce... 286 1e-75
UniRef50_Q4A0Q9 Cluster: Succinate-semialdehyde dehydrogenase; n... 284 3e-75
UniRef50_Q1GID6 Cluster: Betaine-aldehyde dehydrogenase; n=5; Pr... 283 5e-75
UniRef50_A7SDD6 Cluster: Predicted protein; n=1; Nematostella ve... 283 5e-75
UniRef50_A5WDF3 Cluster: Aldehyde dehydrogenase; n=13; Proteobac... 283 7e-75
UniRef50_P25553 Cluster: Aldehyde dehydrogenase A; n=57; Bacteri... 283 7e-75
UniRef50_A5V501 Cluster: Aldehyde dehydrogenase precursor; n=4; ... 283 1e-74
UniRef50_Q397S7 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 282 1e-74
UniRef50_Q0RVI3 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcu... 281 2e-74
UniRef50_Q9RZE6 Cluster: Succinate-semialdehyde dehydrogenase; n... 281 3e-74
UniRef50_Q82GU8 Cluster: Putative aldehyde dehydrogenase; n=1; S... 281 3e-74
UniRef50_A3YHV8 Cluster: Aldehyde dehydrogenase family protein; ... 280 5e-74
UniRef50_A1SJV5 Cluster: Betaine-aldehyde dehydrogenase; n=23; A... 280 7e-74
UniRef50_Q13Q02 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 279 9e-74
UniRef50_Q1ERI2 Cluster: Dehydrogenase; n=1; Monascus purpureus|... 279 2e-73
UniRef50_A6NZ69 Cluster: Putative uncharacterized protein; n=1; ... 278 2e-73
UniRef50_A1UDI2 Cluster: Aldehyde dehydrogenase; n=8; Actinomyce... 277 4e-73
UniRef50_Q6NTJ6 Cluster: LOC414586 protein; n=11; cellular organ... 277 5e-73
UniRef50_Q8YBN0 Cluster: SUCCINATE-SEMIALDEHYDE DEHYDROGENASE; n... 277 5e-73
UniRef50_Q4Q1P8 Cluster: Aldehyde dehydrogenase, putative; n=5; ... 277 5e-73
UniRef50_Q7WPN3 Cluster: Aldehyde dehydrogenase; n=1; Bordetella... 277 6e-73
UniRef50_Q0RV62 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcu... 277 6e-73
UniRef50_Q4L803 Cluster: Putative aldehyde dehydrogenase SH0913;... 277 6e-73
UniRef50_Q1V2Q9 Cluster: Probable aldehyde dehydrogenase; n=2; C... 276 1e-72
UniRef50_A0JU81 Cluster: Succinate-semialdehyde dehydrogenase (N... 276 1e-72
UniRef50_UPI00015BD0F0 Cluster: UPI00015BD0F0 related cluster; n... 275 1e-72
UniRef50_Q8PP06 Cluster: Aldehyde dehydrogenase; n=6; Xanthomona... 275 1e-72
UniRef50_Q7CHE3 Cluster: Succinate-semialdehyde dehydrogenase; n... 275 1e-72
UniRef50_Q7WFF4 Cluster: Putative aldehyde dehydrogenase; n=2; B... 275 2e-72
UniRef50_A1B8X0 Cluster: Aldehyde dehydrogenase (NAD(+)); n=5; R... 275 2e-72
UniRef50_A0H764 Cluster: Aldehyde dehydrogenase; n=1; Comamonas ... 275 2e-72
UniRef50_A4YNG9 Cluster: Aldehyde dehydrogenase; NAD-linked; n=7... 274 3e-72
UniRef50_A1CV82 Cluster: Succinate semialdehyde dehydrogenase; n... 274 3e-72
UniRef50_Q15NZ3 Cluster: Betaine-aldehyde dehydrogenase; n=3; Pr... 274 3e-72
UniRef50_Q6L285 Cluster: Succinate-semialdehyde dehydrogenase [N... 274 3e-72
UniRef50_Q0SCM9 Cluster: NAD-dependent aldehyde dehydrogenase; n... 274 4e-72
UniRef50_Q0S5W5 Cluster: Probable betaine-aldehyde dehydrogenase... 274 4e-72
UniRef50_Q5WBB9 Cluster: Aldehyde dehydrogenase; n=1; Bacillus c... 273 6e-72
UniRef50_Q2G527 Cluster: Betaine-aldehyde dehydrogenase; n=1; No... 273 6e-72
UniRef50_Q13XQ3 Cluster: Aldehyde dehydrogenase; n=7; Burkholder... 273 6e-72
UniRef50_A0QIJ3 Cluster: Aldehyde dehydrogenase; n=4; Mycobacter... 273 6e-72
UniRef50_A0GW39 Cluster: Betaine-aldehyde dehydrogenase; n=2; Ch... 273 6e-72
UniRef50_Q1B5L0 Cluster: Aldehyde dehydrogenase; n=18; Actinomyc... 273 8e-72
UniRef50_O66573 Cluster: Aldehyde dehydrogenase; n=1; Aquifex ae... 272 1e-71
UniRef50_Q3VZS3 Cluster: Betaine-aldehyde dehydrogenase; n=3; Fr... 272 1e-71
UniRef50_Q5HLA7 Cluster: Aldehyde dehydrogenase family protein; ... 272 1e-71
UniRef50_Q0S5S2 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 272 1e-71
UniRef50_Q4WF71 Cluster: Aldehyde dehydrogenase family protein, ... 272 1e-71
UniRef50_A5UKE4 Cluster: NADP-dependent glyceraldehyde-3-phospha... 272 1e-71
UniRef50_A2SRP3 Cluster: Aldehyde dehydrogenase; n=1; Methanocor... 272 2e-71
UniRef50_Q07IS5 Cluster: Aldehyde dehydrogenase; n=1; Rhodopseud... 271 3e-71
UniRef50_A0LMU4 Cluster: Aldehyde dehydrogenase; n=1; Syntrophob... 270 5e-71
UniRef50_Q8TWC7 Cluster: NAD-dependent aldehyde dehydrogenase; n... 270 5e-71
UniRef50_O86742 Cluster: Aldehyde dehydrogenase; n=26; Bacteria|... 270 7e-71
UniRef50_Q1QTL8 Cluster: Betaine-aldehyde dehydrogenase; n=3; Ga... 270 7e-71
UniRef50_Q18Q12 Cluster: Aldehyde dehydrogenase; n=2; Desulfitob... 270 7e-71
UniRef50_Q11E78 Cluster: Aldehyde dehydrogenase; n=3; Alphaprote... 270 7e-71
UniRef50_A3UK81 Cluster: Succinate-semialdehyde dehydrogenase; n... 270 7e-71
UniRef50_Q39LY7 Cluster: Aldehyde dehydrogenase; n=3; Burkholder... 269 1e-70
UniRef50_A0FZ83 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 269 1e-70
UniRef50_Q2BFJ2 Cluster: Putative uncharacterized protein; n=1; ... 268 2e-70
UniRef50_A6C9T4 Cluster: Aldehyde dehydrogenase; n=1; Planctomyc... 268 2e-70
UniRef50_Q5UY93 Cluster: Aldehyde dehydrogenase; n=1; Haloarcula... 268 2e-70
UniRef50_Q97D25 Cluster: NADP-dependent glyceraldehyde-3-phospha... 268 2e-70
UniRef50_Q5QWG0 Cluster: Succinate-semialdehyde dehydrogenase; n... 268 3e-70
UniRef50_A3V8Q9 Cluster: Succinate-semialdehyde dehydrogenase; n... 268 3e-70
UniRef50_Q89RF6 Cluster: Aldehyde dehydrogenase; n=44; Bacteria|... 267 4e-70
UniRef50_A7D1J4 Cluster: Aldehyde dehydrogenase; n=1; Halorubrum... 267 4e-70
UniRef50_P0A391 Cluster: Salicylaldehyde dehydrogenase; n=124; r... 267 4e-70
UniRef50_Q8CJL1 Cluster: Succinate-semialdehyde dehydrogenase; n... 267 5e-70
UniRef50_Q11BU1 Cluster: Aldehyde dehydrogenase; n=1; Mesorhizob... 267 5e-70
UniRef50_Q75TD2 Cluster: Aldehyde dehydrogenase family; n=14; Ba... 266 7e-70
UniRef50_Q15SR9 Cluster: Betaine-aldehyde dehydrogenase; n=3; Ba... 266 7e-70
UniRef50_Q9A9Y9 Cluster: Aldehyde dehydrogenase; n=1; Caulobacte... 266 9e-70
UniRef50_Q987P9 Cluster: Aldehyde dehydrogenase; n=32; Bacteria|... 266 1e-69
UniRef50_A0K0Z7 Cluster: Aldehyde dehydrogenase; n=10; Bacteria|... 266 1e-69
UniRef50_A0QXQ5 Cluster: Aldehyde dehydrogenase (NAD) family pro... 265 2e-69
UniRef50_Q59702 Cluster: P-hydroxybenzaldehyde dehydrogenase; n=... 264 3e-69
UniRef50_Q026K2 Cluster: Aldehyde dehydrogenase; n=1; Solibacter... 264 3e-69
UniRef50_A0JW58 Cluster: Betaine-aldehyde dehydrogenase; n=19; B... 264 4e-69
UniRef50_Q9KC36 Cluster: NADP-dependent glyceraldehyde-3-phospha... 264 5e-69
UniRef50_A0G1X4 Cluster: Aldehyde dehydrogenase; n=1; Burkholder... 264 5e-69
UniRef50_Q5YUM9 Cluster: Putative aldehyde dehydrogenase; n=1; N... 263 6e-69
UniRef50_Q129N3 Cluster: Aldehyde dehydrogenase; n=3; Burkholder... 263 6e-69
UniRef50_Q11FM4 Cluster: Aldehyde dehydrogenase; n=22; Proteobac... 263 6e-69
UniRef50_A7K2K3 Cluster: NAD-dependent aldehyde dehydrogenase; n... 263 6e-69
UniRef50_Q8EMY3 Cluster: Benzaldehyde dehydrogenase; n=3; Bacter... 263 8e-69
UniRef50_Q3W9W9 Cluster: Betaine-aldehyde dehydrogenase; n=1; Fr... 263 8e-69
UniRef50_Q28KS0 Cluster: Aldehyde dehydrogenase; n=1; Jannaschia... 262 1e-68
UniRef50_Q1GR97 Cluster: Succinate-semialdehyde dehydrogenase (N... 262 1e-68
UniRef50_A5V6N4 Cluster: Aldehyde dehydrogenase; n=1; Sphingomon... 262 2e-68
UniRef50_O02266 Cluster: Putative uncharacterized protein alh-7;... 261 3e-68
UniRef50_A3SJ18 Cluster: Aldehyde dehydrogenase; n=1; Roseovariu... 260 4e-68
UniRef50_Q21B13 Cluster: Aldehyde dehydrogenase; n=3; Alphaprote... 260 6e-68
UniRef50_A7K6M3 Cluster: NAD-dependent aldehyde dehydrogenase; n... 260 6e-68
UniRef50_A0FZA2 Cluster: Aldehyde dehydrogenase; n=2; Proteobact... 260 8e-68
UniRef50_Q391G7 Cluster: Betaine-aldehyde dehydrogenase; n=5; Bu... 259 1e-67
UniRef50_Q12AS3 Cluster: Betaine-aldehyde dehydrogenase; n=69; B... 259 1e-67
UniRef50_Q5PHV8 Cluster: Gamma-aminobutyraldehyde dehydrogenase;... 259 1e-67
UniRef50_Q74E56 Cluster: Aldehyde dehydrogenase family protein; ... 259 1e-67
UniRef50_Q7SET1 Cluster: Putative uncharacterized protein NCU007... 258 2e-67
UniRef50_Q0UBM0 Cluster: Putative uncharacterized protein; n=1; ... 258 2e-67
UniRef50_Q1QTY6 Cluster: Aldehyde dehydrogenase; n=17; Proteobac... 258 3e-67
UniRef50_Q0SJS7 Cluster: Probable betaine-aldehyde dehydrogenase... 258 3e-67
UniRef50_Q1J3K0 Cluster: Aldehyde dehydrogenase; n=1; Deinococcu... 257 5e-67
UniRef50_Q9K9B2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 256 1e-66
UniRef50_A1B6Z8 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 256 1e-66
UniRef50_Q8XHP4 Cluster: NADP-dependent glyceraldehyde-3-phospha... 254 3e-66
UniRef50_Q2G4I6 Cluster: Aldehyde dehydrogenase; n=2; Sphingomon... 254 3e-66
UniRef50_A4C0I7 Cluster: NADP-dependent glyceraldehyde-3-phospha... 254 3e-66
UniRef50_Q7NGY2 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 254 5e-66
UniRef50_A5V808 Cluster: Aldehyde dehydrogenase; n=1; Sphingomon... 254 5e-66
UniRef50_A1UJD4 Cluster: Aldehyde dehydrogenase; n=9; Actinomyce... 254 5e-66
UniRef50_P42412 Cluster: Probable methylmalonate-semialdehyde de... 254 5e-66
UniRef50_A1B0W9 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; P... 253 9e-66
UniRef50_Q471V4 Cluster: Aldehyde dehydrogenase; n=11; Proteobac... 252 1e-65
UniRef50_A3VIJ9 Cluster: Aldehyde dehydrogenase; n=2; Rhodobacte... 252 2e-65
UniRef50_Q11CB7 Cluster: Aldehyde dehydrogenase; n=16; cellular ... 252 2e-65
UniRef50_Q0S4P3 Cluster: Dehydrogenase; n=1; Rhodococcus sp. RHA... 252 2e-65
UniRef50_Q98EK8 Cluster: Aldehyde dehydrogenase; n=1; Mesorhizob... 251 3e-65
UniRef50_Q11EZ6 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 251 4e-65
UniRef50_A3WI91 Cluster: Succinate-semialdehyde dehydrogenase (N... 251 4e-65
UniRef50_Q1LBV2 Cluster: Aldehyde dehydrogenase; n=7; Proteobact... 250 5e-65
UniRef50_A0PMJ5 Cluster: NAD-dependent aldehyde dehydrogenase, A... 250 5e-65
UniRef50_A2XUD1 Cluster: Putative uncharacterized protein; n=1; ... 250 5e-65
UniRef50_Q58806 Cluster: Putative aldehyde-dehydrogenase-like pr... 250 6e-65
UniRef50_A7D6M8 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; H... 250 8e-65
UniRef50_A1RR47 Cluster: Succinate-semialdehyde dehydrogenase (N... 250 8e-65
UniRef50_Q2KVI1 Cluster: Succinate-semialdehyde dehydrogenase [N... 249 1e-64
UniRef50_A0VT45 Cluster: Aldehyde dehydrogenase (NAD(+)); n=2; P... 249 1e-64
UniRef50_A1T677 Cluster: Aldehyde dehydrogenase; n=2; Mycobacter... 249 1e-64
UniRef50_Q7WBK1 Cluster: Probable aldehyde dehydrogenase; n=2; B... 248 3e-64
UniRef50_Q6MNK1 Cluster: 1-pyrroline-5 carboxylate dehydrogenase... 248 3e-64
UniRef50_Q4P2R3 Cluster: Putative uncharacterized protein; n=1; ... 248 3e-64
UniRef50_A1UDX1 Cluster: Aldehyde dehydrogenase; n=43; Actinomyc... 247 6e-64
UniRef50_P43503 Cluster: Benzaldehyde dehydrogenase [NAD+]; n=6;... 247 6e-64
UniRef50_Q9RKF1 Cluster: Putative aldehyde dehydrogenase; n=1; S... 246 8e-64
UniRef50_Q98A95 Cluster: Aldehyde dehydrogenase; n=2; Mesorhizob... 246 1e-63
UniRef50_Q1GUQ2 Cluster: Betaine-aldehyde dehydrogenase; n=3; Pr... 245 2e-63
UniRef50_A0JVP7 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; A... 245 2e-63
UniRef50_Q9X5T0 Cluster: MmcL; n=1; Streptomyces lavendulae|Rep:... 245 2e-63
UniRef50_Q1GUT3 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 245 2e-63
UniRef50_A0QUC9 Cluster: Aldehyde dehydrogenase; n=1; Mycobacter... 244 3e-63
UniRef50_A1SGK0 Cluster: Aldehyde dehydrogenase; n=1; Nocardioid... 244 5e-63
UniRef50_A6CAL5 Cluster: 1-pyrroline-5 carboxylate dehydrogenase... 243 9e-63
UniRef50_A5WEU6 Cluster: Aldehyde dehydrogenase; n=13; Proteobac... 241 2e-62
UniRef50_Q1LBS3 Cluster: Aldehyde dehydrogenase; n=1; Ralstonia ... 241 3e-62
UniRef50_Q97YT9 Cluster: Methylmalonate-semialdehyde dehydrogena... 241 3e-62
UniRef50_A0Z1D1 Cluster: Aldehyde dehydrogenase; n=1; marine gam... 240 5e-62
UniRef50_Q39NY4 Cluster: Aldehyde dehydrogenase; n=53; Bacteria|... 240 7e-62
UniRef50_Q391C0 Cluster: Aldehyde dehydrogenase; n=3; Proteobact... 240 7e-62
UniRef50_Q92HZ9 Cluster: Succinate semialdehyde dehydrogenase [E... 239 9e-62
UniRef50_Q4P911 Cluster: Putative uncharacterized protein; n=1; ... 239 1e-61
UniRef50_Q2URV0 Cluster: Aldehyde dehydrogenase; n=6; Pezizomyco... 239 2e-61
UniRef50_Q470B3 Cluster: Betaine-aldehyde dehydrogenase; n=1; Ra... 238 2e-61
UniRef50_Q1IRQ5 Cluster: Succinate-semialdehyde dehydrogenase (N... 238 3e-61
UniRef50_Q39GA8 Cluster: Aldehyde dehydrogenase; n=2; Betaproteo... 237 5e-61
UniRef50_A0K0R6 Cluster: Aldehyde dehydrogenase (NAD(+)); n=14; ... 237 5e-61
UniRef50_Q0RL40 Cluster: Putative NAD+-dependent betaine aldehyd... 236 8e-61
UniRef50_Q743I3 Cluster: AldA_1; n=4; Corynebacterineae|Rep: Ald... 235 1e-60
UniRef50_Q0S1Y5 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcu... 235 1e-60
UniRef50_Q0RZN4 Cluster: Probable betaine-aldehyde dehydrogenase... 235 1e-60
UniRef50_A1SPP3 Cluster: Aldehyde dehydrogenase; n=4; Actinomyce... 235 1e-60
UniRef50_Q2L0G5 Cluster: Betaine aldehyde dehydrogenase; n=10; P... 235 3e-60
UniRef50_P94358 Cluster: AldY protein; n=2; Bacillus|Rep: AldY p... 235 3e-60
UniRef50_Q0CEH6 Cluster: Putative uncharacterized protein; n=2; ... 235 3e-60
UniRef50_A7DPV1 Cluster: Aldehyde dehydrogenase; n=1; Candidatus... 235 3e-60
UniRef50_A7HAX3 Cluster: Methylmalonate-semialdehyde dehydrogena... 234 3e-60
UniRef50_Q8NIT1 Cluster: Related to aldehyde dehydrogenase (NAD+... 234 3e-60
UniRef50_Q5UZM4 Cluster: Aldehyde dehydrogenase; n=4; Halobacter... 234 3e-60
UniRef50_Q9KHU2 Cluster: Aldehyde dehydrogenase; n=9; Actinomyce... 234 4e-60
UniRef50_Q8ERF4 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 233 6e-60
UniRef50_Q8RYB8 Cluster: Aldehyde dehydrogenase Aldh21A1; n=1; T... 233 8e-60
UniRef50_Q1ATU1 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacte... 233 1e-59
UniRef50_Q47QE4 Cluster: Betaine-aldehyde dehydrogenase; n=1; Th... 232 2e-59
UniRef50_A0Q473 Cluster: Succinate semialdehyde dehydrogenase (N... 231 3e-59
UniRef50_Q72KD3 Cluster: Aldehyde dehydrogenase; n=2; Thermus th... 231 4e-59
UniRef50_Q2GA81 Cluster: Succinate-semialdehyde dehydrogenase (N... 230 5e-59
UniRef50_Q28KQ6 Cluster: Aldehyde dehydrogenase; n=2; Rhodobacte... 230 5e-59
UniRef50_Q1AXK7 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacte... 230 5e-59
UniRef50_A0JWA6 Cluster: Aldehyde dehydrogenase; n=3; Actinomyce... 230 5e-59
UniRef50_A0JTV0 Cluster: Aldehyde dehydrogenase; n=4; Actinobact... 230 5e-59
UniRef50_Q0RMH3 Cluster: Aldehyde dehydrogenase, an ethanol-util... 230 7e-59
UniRef50_Q8ELI8 Cluster: Aldehyde dehydrogenase; n=2; Bacillacea... 229 9e-59
UniRef50_Q5B7A7 Cluster: Putative uncharacterized protein; n=2; ... 229 9e-59
UniRef50_Q97XS9 Cluster: Glyceraldehyde-3-phosphate dehydrogenas... 229 1e-58
UniRef50_A2Q7G4 Cluster: Function: converts p-cumic aldehyde + H... 227 4e-58
UniRef50_Q47LP9 Cluster: Aldehyde dehydrogenase; n=2; cellular o... 227 7e-58
UniRef50_Q7VZI8 Cluster: Putative succinate-semialdehyde dehydro... 226 9e-58
UniRef50_Q5IW32 Cluster: Putative PhpJ; n=2; Streptomyces|Rep: P... 226 9e-58
UniRef50_Q15XG6 Cluster: Aldehyde dehydrogenase; n=1; Pseudoalte... 226 1e-57
UniRef50_Q0RC34 Cluster: Putative aldehyde dehydrogenase; n=1; F... 226 1e-57
UniRef50_A6EQ45 Cluster: Aldehyde dehydrogenase; n=1; unidentifi... 226 1e-57
UniRef50_Q746X3 Cluster: Proline dehydrogenase/delta-1-pyrroline... 223 6e-57
UniRef50_Q5UZ87 Cluster: Aldehyde dehydrogenase; n=4; Halobacter... 223 8e-57
UniRef50_UPI0000DA2DE8 Cluster: PREDICTED: similar to aldehyde d... 223 1e-56
UniRef50_Q1Q6B2 Cluster: Similar to aldehyde dehydrogenase; n=1;... 223 1e-56
UniRef50_Q1IRG7 Cluster: Aldehyde dehydrogenase; n=4; Bacteria|R... 222 1e-56
UniRef50_Q6ZV71 Cluster: CDNA FLJ42918 fis, clone BRHIP3027137, ... 222 1e-56
UniRef50_A0QZI6 Cluster: Vanillin dehydrogenase; n=1; Mycobacter... 222 2e-56
UniRef50_A6S4N0 Cluster: Putative uncharacterized protein; n=3; ... 221 3e-56
UniRef50_A1SPF0 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|R... 221 3e-56
UniRef50_A0QZV7 Cluster: [NAD+] benzaldehyde dehydrogenase; n=1;... 221 3e-56
UniRef50_Q4P685 Cluster: Putative uncharacterized protein; n=1; ... 221 3e-56
UniRef50_A5VEC2 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 221 4e-56
UniRef50_Q7DA77 Cluster: Succinate-semialdehyde dehydrogenase; n... 220 6e-56
UniRef50_Q54WJ9 Cluster: Aldehyde dehydrogenase; n=1; Dictyostel... 219 1e-55
UniRef50_Q8NM66 Cluster: NAD-dependent aldehyde dehydrogenases; ... 219 1e-55
UniRef50_A3V8C6 Cluster: Putative uncharacterized protein; n=1; ... 219 1e-55
UniRef50_A3CSZ2 Cluster: Aldehyde dehydrogenase; n=2; Methanomic... 219 1e-55
UniRef50_A7PD75 Cluster: Chromosome chr17 scaffold_12, whole gen... 219 2e-55
UniRef50_A1DAT0 Cluster: Aldehyde dehydrogenase; n=1; Neosartory... 219 2e-55
UniRef50_Q9YB09 Cluster: NADP-dependent glyceraldehyde-3-phospha... 219 2e-55
UniRef50_Q53197 Cluster: Putative aldehyde-dehydrogenase-like pr... 219 2e-55
UniRef50_Q9ZBH2 Cluster: Putative aldehyde dehydrogenase; n=4; S... 217 5e-55
UniRef50_A7S3J2 Cluster: Predicted protein; n=1; Nematostella ve... 216 1e-54
UniRef50_A4WI87 Cluster: Methylmalonate-semialdehyde dehydrogena... 216 1e-54
UniRef50_A1SMU8 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|R... 215 2e-54
UniRef50_A1SNW6 Cluster: Aldehyde dehydrogenase (NAD(+)); n=2; A... 215 3e-54
UniRef50_Q2UB89 Cluster: Aldehyde dehydrogenase; n=1; Aspergillu... 215 3e-54
UniRef50_A1SFP6 Cluster: Betaine-aldehyde dehydrogenase; n=1; No... 214 5e-54
UniRef50_A0ADR8 Cluster: Putative aldehyde dehydrogenase; n=1; S... 214 5e-54
UniRef50_Q28MS3 Cluster: Aldehyde dehydrogenase; n=1; Jannaschia... 213 7e-54
UniRef50_A0DNR6 Cluster: Chromosome undetermined scaffold_58, wh... 213 7e-54
UniRef50_A1CRU5 Cluster: Vanillin dehydrogenase, putative; n=14;... 213 7e-54
UniRef50_O32507 Cluster: Succinate-semialdehyde dehydrogenase [N... 213 7e-54
UniRef50_Q84H87 Cluster: 6-oxohexanoate dehydrogenase; n=1; Arth... 213 9e-54
UniRef50_Q122Y7 Cluster: Benzaldehyde dehydrogenase; n=23; Bacte... 213 9e-54
UniRef50_A4W665 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 213 9e-54
UniRef50_A1UAI4 Cluster: Aldehyde dehydrogenase; n=6; Mycobacter... 213 1e-53
UniRef50_Q1AY01 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|R... 212 2e-53
UniRef50_Q9RZC4 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 212 2e-53
UniRef50_Q7WPE0 Cluster: Putative aldehyde dehydrogenase; n=1; B... 212 2e-53
UniRef50_Q1IUR8 Cluster: Succinate-semialdehyde dehydrogenase (N... 212 2e-53
UniRef50_A0FZB4 Cluster: Aldehyde dehydrogenase; n=1; Burkholder... 212 2e-53
UniRef50_A2R9D4 Cluster: Contig An17c0040, complete genome; n=1;... 211 3e-53
UniRef50_Q0I933 Cluster: Aldehyde dehydrogenase family protein; ... 211 4e-53
UniRef50_A6Q709 Cluster: Aldehyde dehydrogenase; n=3; Epsilonpro... 211 4e-53
UniRef50_Q703Z2 Cluster: Aldehyde dehydrogenase; n=1; Thermoprot... 211 4e-53
UniRef50_Q82TA7 Cluster: Aldehyde dehydrogenase family; n=2; Nit... 210 5e-53
UniRef50_P76149 Cluster: Aldehyde dehydrogenase-like protein yne... 210 5e-53
UniRef50_Q30PA8 Cluster: Aldehyde dehydrogenase; n=1; Thiomicros... 210 8e-53
UniRef50_Q0SCY4 Cluster: Benzaldehyde dehydrogenase; n=6; Bacter... 209 1e-52
UniRef50_Q02252 Cluster: Methylmalonate-semialdehyde dehydrogena... 209 1e-52
UniRef50_Q1R0P4 Cluster: Aldehyde dehydrogenase; n=1; Chromohalo... 208 2e-52
UniRef50_A6G099 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1; P... 208 2e-52
UniRef50_A4CLA9 Cluster: Succinate-semialdehyde dehydrogenase; n... 208 2e-52
UniRef50_Q4P767 Cluster: Putative uncharacterized protein; n=1; ... 208 2e-52
UniRef50_A6VY50 Cluster: Aldehyde dehydrogenase; n=6; Proteobact... 208 3e-52
UniRef50_A4A508 Cluster: Aldehyde dehydrogenase, NADP-dependent;... 208 3e-52
UniRef50_Q2BC75 Cluster: Aldehyde dehydrogenase; n=1; Bacillus s... 207 4e-52
UniRef50_Q8NT34 Cluster: NAD-dependent aldehyde dehydrogenases; ... 207 6e-52
UniRef50_Q4JC93 Cluster: Aldehyde dehydrogenase; n=2; Sulfolobac... 207 6e-52
UniRef50_A4YFT0 Cluster: Aldehyde dehydrogenase; n=3; Thermoprot... 207 6e-52
UniRef50_UPI0000E0E9DF Cluster: succinate-semialdehyde dehydroge... 206 8e-52
UniRef50_Q88T90 Cluster: Succinate-semialdehyde dehydrogenase (N... 206 8e-52
UniRef50_A6DSV0 Cluster: NAD-dependent aldehyde dehydrogenase; n... 206 8e-52
UniRef50_A3X3C3 Cluster: Aldehyde dehydrogenase; n=1; Roseobacte... 206 1e-51
UniRef50_Q47YT5 Cluster: Aldehyde dehydrogenase family protein; ... 205 2e-51
UniRef50_Q393E4 Cluster: Aldehyde dehydrogenase; n=27; cellular ... 205 2e-51
UniRef50_Q1WIQ6 Cluster: NADP-dependent glyceraldehyde-3-phospha... 205 2e-51
UniRef50_Q5KH03 Cluster: Aldehyde dehydrogenase, putative; n=2; ... 204 3e-51
UniRef50_Q89N88 Cluster: Methylmalonate-semialdehyde dehydrogena... 204 4e-51
UniRef50_Q63MP3 Cluster: Aldehyde dehydrogenase family protein; ... 204 4e-51
UniRef50_Q1IRG5 Cluster: Methylmalonate-semialdehyde dehydrogena... 204 5e-51
UniRef50_Q5BYA8 Cluster: SJCHGC00475 protein; n=3; Schistosoma j... 204 5e-51
UniRef50_Q9HQZ2 Cluster: Glyceraldehyde-3-phosphate dehydrogenas... 204 5e-51
UniRef50_A0L5V5 Cluster: Aldehyde dehydrogenase; n=1; Magnetococ... 203 7e-51
UniRef50_Q55585 Cluster: Probable succinate-semialdehyde dehydro... 203 7e-51
UniRef50_Q3W5F5 Cluster: Aldehyde dehydrogenase; n=3; Actinomyce... 203 9e-51
UniRef50_Q086S9 Cluster: Aldehyde dehydrogenase (NAD(+)); n=9; P... 203 9e-51
UniRef50_Q4WC68 Cluster: Aldehyde dehydrogenase family protein; ... 203 9e-51
UniRef50_UPI000051030C Cluster: COG1012: NAD-dependent aldehyde ... 202 1e-50
UniRef50_UPI000023DDDF Cluster: hypothetical protein FG07803.1; ... 202 2e-50
UniRef50_P96417 Cluster: POSSIBLE SUCCINATE-SEMIALDEHYDE DEHYDRO... 202 2e-50
UniRef50_Q082D7 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|R... 202 2e-50
UniRef50_Q122F7 Cluster: Aldehyde dehydrogenase; n=2; Comamonada... 201 3e-50
UniRef50_A3EST8 Cluster: NAD-dependent aldehyde dehydrogenase; n... 201 3e-50
UniRef50_P28810 Cluster: Methylmalonate-semialdehyde dehydrogena... 201 3e-50
UniRef50_A0P001 Cluster: Dehydrogenase; n=1; Stappia aggregata I... 201 4e-50
UniRef50_Q09DC3 Cluster: 1-pyrroline-5-carboxylate dehydrogenase... 200 5e-50
UniRef50_Q9JZ02 Cluster: Aldehyde dehydrogenase family protein; ... 200 9e-50
UniRef50_A6W065 Cluster: Aldehyde dehydrogenase; n=1; Marinomona... 199 2e-49
UniRef50_A1WYH8 Cluster: Aldehyde dehydrogenase; n=6; Gammaprote... 199 2e-49
UniRef50_Q0CIG5 Cluster: Putative uncharacterized protein; n=2; ... 199 2e-49
UniRef50_Q5UWF4 Cluster: Succinate-semialdehyde dehydrogenase; n... 198 2e-49
UniRef50_A3I4V1 Cluster: Methylmalonate-semialdehyde dehydrogena... 198 3e-49
UniRef50_A3ER29 Cluster: NAD-dependent aldehyde dehydrogenase; n... 198 3e-49
UniRef50_Q2I6M0 Cluster: NADP-dependent aldehyde dehydrogenase; ... 198 4e-49
UniRef50_A7EL38 Cluster: Putative uncharacterized protein; n=1; ... 198 4e-49
UniRef50_Q8EVT9 Cluster: NADP-dependent glyceraldehyde-3-phospha... 197 5e-49
UniRef50_Q9WXH4 Cluster: 2-carboxybenzaldehyde dehydrogenase; n=... 197 6e-49
UniRef50_A1D0S1 Cluster: Succinate semialdehyde dehydrogenase; n... 197 6e-49
UniRef50_Q979S8 Cluster: Aldehyde dehydrogenase; n=19; cellular ... 197 6e-49
UniRef50_Q9HKJ5 Cluster: Aldehyde dehydrogenase related protein;... 196 1e-48
UniRef50_Q0RWB8 Cluster: Methylmalonate-semialdehyde dehydrogena... 195 2e-48
UniRef50_Q8KC53 Cluster: Aldehyde dehydrogenase family protein; ... 195 2e-48
UniRef50_A6GKH6 Cluster: Succinate-semialdehyde dehydrogenase (N... 195 2e-48
UniRef50_A3TND9 Cluster: Methylmalonate-semialdehyde dehydrogena... 195 2e-48
UniRef50_A1YBR4 Cluster: AmbN; n=1; Sorangium cellulosum|Rep: Am... 195 2e-48
UniRef50_Q39H94 Cluster: Methylmalonate-semialdehyde dehydrogena... 194 4e-48
UniRef50_Q0SC54 Cluster: Aldehyde dehydrogenase; n=3; Corynebact... 194 4e-48
>UniRef50_P13601 Cluster: Aldehyde dehydrogenase, cytosolic 1; n=15;
cellular organisms|Rep: Aldehyde dehydrogenase,
cytosolic 1 - Rattus norvegicus (Rat)
Length = 501
Score = 537 bits (1324), Expect = e-151
Identities = 258/483 (53%), Positives = 339/483 (70%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I++TK+FI+NEW ++ +G+ F +P VI V +G FQ S
Sbjct: 17 KIQHTKIFINNEWHNSLNGKKFPVINPATEEVICHVEEGDKADVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSL 122
WR DAS+RG LL K ADL+ERD LA +ES + G ++ + + + + +++Y
Sbjct: 77 WRTMDASERGCLLNKLADLMERDRVLLATMESMNAGKIFTHAYLLDTEVSIKALKYFAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKI G TIP+DGD F+YT ++P+GVCG I+PWN P+++F+ K+ AL+ G TV+VKPAE
Sbjct: 137 ADKIHGQTIPSDGDVFTYTRREPIGVCGQIIPWNGPLILFIWKIGAALSCGNTVIVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVN+VPG+G AG A++ H D+ K+SFTGS EVGKLI++
Sbjct: 197 QTPLTALYMASLIKEAGFPPGVVNVVPGYGSTAGAAISSHMDIDKVSFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I+ DADL+ A+ +A GVFFHQGQICVAASRL+V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVFADADLDSAVEFAHQGVFFHQGQICVAASRLFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP D GPQID+ K+L LIE+GKKEGA L GG R G
Sbjct: 317 DEFVRRSVERAKKYVLGNPLDSGISQGPQIDKEQHAKILDLIESGKKEGAKLECGGGRWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G+++QPTVF++V D+M IAKEEIFGPVQ I+KF +++EVI RANNT YGLAAG+FT +
Sbjct: 377 NKGFFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSIDEVIKRANNTPYGLAAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ A+ S ++AGTVWVN YLT++ Q PFGGFK SG GRE G + V Y E KTV + +
Sbjct: 437 LDRAITVSSALQAGTVWVNCYLTLSVQCPFGGFKMSGNGREMGEQGVYEYTELKTVAMKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>UniRef50_P30837 Cluster: Aldehyde dehydrogenase X, mitochondrial
precursor; n=121; cellular organisms|Rep: Aldehyde
dehydrogenase X, mitochondrial precursor - Homo sapiens
(Human)
Length = 517
Score = 515 bits (1270), Expect = e-144
Identities = 251/484 (51%), Positives = 320/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I Y +LFI+NEW DA +TF T +P G VI VA+G F+ S
Sbjct: 32 PDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
WR DAS+RG+LL ADL+ERD YLA LE+ DNG ++ + L + RY
Sbjct: 92 PWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DG F +T +PVGVCG I+PWN P++M K+ ALA G TVV+K A
Sbjct: 152 WADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPL+ KEAG P GVVNI+ G+G AG A+ H DV K++FTGS EVG LIQ
Sbjct: 212 EQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
KAAG +NLKRVTLELGGKSP I++ DAD+ A+ +FF+ GQ C A SR +V+ I
Sbjct: 272 KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y++F++ VE AK +VGNPF+ T GPQ+D+ +VLG I+ G+KEGA LL GGER
Sbjct: 332 YNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++I+PTVF V DDM IAKEEIFGPVQ + KF +EEV++RANNT YGLAA +FT
Sbjct: 392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A+ F++ ++AGTVWVN Y + PFGGFK+SG GRE G ++AY E KTV I
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>UniRef50_Q56YU0 Cluster: Aldehyde dehydrogenase 2C4, cytosolic;
n=14; Spermatophyta|Rep: Aldehyde dehydrogenase 2C4,
cytosolic - Arabidopsis thaliana (Mouse-ear cress)
Length = 501
Score = 484 bits (1193), Expect = e-135
Identities = 241/485 (49%), Positives = 324/485 (66%), Gaps = 7/485 (1%)
Query: 2 VPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRN 61
+PEIK+TKLFI+ +++DA G+TF+T P +G VIA +A+G F +
Sbjct: 14 LPEIKFTKLFINGQFIDAASGKTFETIDPRNGEVIATIAEGDKEDVDLAVNAARYAFD-H 72
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RY 118
W +R KL+ KFADLIE + E LAKL++ D G +++ L + IP + RY
Sbjct: 73 GPWPRMTGFERAKLINKFADLIEENIEELAKLDAVDGGKLFQ--LGKYADIPATAGHFRY 130
Query: 119 LGSLADKIQGDTIPTDGDS-FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
ADKI G+T+ S F YTLK+P+GV G I+PWN P +MF KV A+AAGCT+V
Sbjct: 131 NAGAADKIHGETLKMTRQSLFGYTLKEPIGVVGNIIPWNFPSIMFATKVAPAMAAGCTMV 190
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
VKPAEQT L+ KEAGIP GV+NIV GFG AG A+ H DV K+SFTGS +VG
Sbjct: 191 VKPAEQTSLSALFYAHLSKEAGIPDGVLNIVTGFGSTAGAAIASHMDVDKVSFTGSTDVG 250
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
+ I +AA +NLK+V+LELGGKSPL+I NDAD++ A A G F+++G+ICVA+SR++V
Sbjct: 251 RKIMQAAAASNLKKVSLELGGKSPLLIFNDADIDKAADLALLGCFYNKGEICVASSRVFV 310
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
Q GIYDK V+ VE AK VG+PFD + GPQ+D+ K+L IE GK EGA LL G
Sbjct: 311 QEGIYDKVVEKLVEKAKDWTVGDPFDSTARQGPQVDKRQFEKILSYIEHGKNEGATLLTG 370
Query: 358 GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G+ IG GY+IQPT+FADV +DM I ++EIFGPV S++KF T+EE I ANNT YGLAAG
Sbjct: 371 GKAIGDKGYFIQPTIFADVTEDMKIYQDEIFGPVMSLMKFKTVEEGIKCANNTKYGLAAG 430
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
I + +++ S+ ++AG +WVN Y P+GG+K SG RE+G+ A++ YL+ K+
Sbjct: 431 ILSQDIDLINTVSRSIKAGIIWVNCYFGFDLDCPYGGYKMSGNCRESGMDALDNYLQTKS 490
Query: 478 VIISL 482
V++ L
Sbjct: 491 VVMPL 495
>UniRef50_Q29AE2 Cluster: GA15986-PA; n=1; Drosophila
pseudoobscura|Rep: GA15986-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 526
Score = 481 bits (1187), Expect = e-134
Identities = 249/518 (48%), Positives = 328/518 (63%), Gaps = 42/518 (8%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
KYTKLFI+NE+VDA G+TF T +P G I KVA+G F RNS+WR
Sbjct: 9 KYTKLFINNEFVDAVSGKTFATSNPATGKEIVKVAEGDKADVDLAVIAAKKAFHRNSDWR 68
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
QR L+ K L+ERD E+LA LE+ DNG Y L ++ +++Y DK
Sbjct: 69 KLSPLQRTNLINKLCALMERDKEFLASLETQDNGKPYAEALFDVTYSILTLQYYAGWTDK 128
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
GDTIP G + S T K+PVGV G I+PWN P+LM K ALA GCT+++KPAEQTP
Sbjct: 129 FFGDTIPAGGFT-SMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTP 187
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT KEAG P GV+NI+ GFG AG A++ HPD+AK++FTGS+++G+++ +AA
Sbjct: 188 LTALHMAALTKEAGFPAGVINIINGFGPTAGAAISEHPDIAKVAFTGSVDIGRIVMQAAA 247
Query: 246 TNNLKRVTLELGGKSPLIIMNDAD--------------------LNLAIPYAGSGVFFHQ 285
+NLKRV+LELGGKSP+++ +DAD ++ A+ +F +
Sbjct: 248 KSNLKRVSLELGGKSPVVVFDDADSKYRLDSLSSSGLNANLILLVDFAVETTHEALFSNH 307
Query: 286 GQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIE 345
GQ C A SR YV IYDKFV+ A AKA +VGNPF+E+ GPQID+ M KVLG IE
Sbjct: 308 GQSCCAGSRTYVHEKIYDKFVEKAAAKAKARKVGNPFEENVQQGPQIDQEMFTKVLGYIE 367
Query: 346 TGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEE------------------- 386
+G+KEGA L AGG+RIG G++I+PTVF+DV D+M IA+EE
Sbjct: 368 SGQKEGAKLQAGGKRIGNVGFFIEPTVFSDVKDNMKIAQEEVRTLRSSLQNHPLMGSLSC 427
Query: 387 --IFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYL 444
IFGPVQSI KF +L+E+IDRANN YGLAAGI T ++N AL+F+ +V+AG+VW+N Y
Sbjct: 428 LQIFGPVQSIFKFSSLDEIIDRANNVQYGLAAGIITNDINKALKFANNVDAGSVWINCYD 487
Query: 445 TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ + PFGG+K SGIGRE G ++ YLE KT+ + L
Sbjct: 488 AVLPETPFGGYKHSGIGRELGKDGLDNYLETKTITMKL 525
>UniRef50_P40108 Cluster: Aldehyde dehydrogenase; n=5; cellular
organisms|Rep: Aldehyde dehydrogenase - Cladosporium
herbarum (Davidiella tassiana)
Length = 496
Score = 460 bits (1133), Expect = e-128
Identities = 228/475 (48%), Positives = 302/475 (63%), Gaps = 2/475 (0%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T LFI+NE+V ++G+TFD +P D SVI +V + F+ WR
Sbjct: 18 TGLFINNEFVKGQEGKTFDVINPSDESVITQVHEATEKDVDIAVAAARKAFE--GSWRQE 75
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
RGKLL A+L E++ + LA +ES DNG +S +RY G ADKI
Sbjct: 76 TPENRGKLLNNLANLFEKNIDLLAAVESLDNGKAISMAKGDISMCVGCLRYYGGWADKIT 135
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G I T D+F+Y K+P+GVCG I+PWN P+LM+ K+ A+A G TVV+K AEQTPL
Sbjct: 136 GKVIDTTPDTFNYVKKEPIGVCGQIIPWNFPLLMWAWKIGPAIACGNTVVLKTAEQTPLG 195
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
KEAG P GV+N++ GFG+ AG AL+ H DV K++FTGS VG+ I KAA ++
Sbjct: 196 GLVAASLVKEAGFPPGVINVISGFGKVAGAALSSHMDVDKVAFTGSTVVGRTILKAAASS 255
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NLK+VTLELGGKSP I+ DAD++ AI + G+FF+ GQ C A SR+YVQ IYDKFV+
Sbjct: 256 NLKKVTLELGGKSPNIVFEDADIDNAISWVNFGIFFNHGQCCCAGSRVYVQESIYDKFVQ 315
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
E A+ VG+PF T GPQ+ + ++++ I+ GK GA + GG+R G GY+
Sbjct: 316 KFKERAQKNVVGDPFAADTFQGPQVSKVQFDRIMEYIQAGKDAGATVETGGKRKGDKGYF 375
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
I+PT+F++V +DM I KEEIFGPV SI KF T E+ I N + YGLAA + T NLN A+
Sbjct: 376 IEPTIFSNVTEDMKIVKEEIFGPVCSIAKFKTKEDAIKLGNASTYGLAAAVHTKNLNTAI 435
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ S ++AGTVWVN Y T+ HQ PFGG+K+SGIGRE G A+ Y + KTV I L
Sbjct: 436 EVSNALKAGTVWVNTYNTLHHQMPFGGYKESGIGRELGEDALANYTQTKTVSIRL 490
>UniRef50_P46367 Cluster: Potassium-activated aldehyde
dehydrogenase, mitochondrial precursor (EC 1.2.1.3)
(K(+)-activated acetaldehyde dehydrogenase) (K(+)-ACDH);
n=25; Saccharomycetales|Rep: Potassium-activated
aldehyde dehydrogenase, mitochondrial precursor (EC
1.2.1.3) (K(+)-activated acetaldehyde dehydrogenase)
(K(+)-ACDH) - Saccharomyces cerevisiae (Baker's yeast)
Length = 519
Score = 442 bits (1088), Expect = e-122
Identities = 211/471 (44%), Positives = 300/471 (63%), Gaps = 2/471 (0%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T LFI+N++V +K +TF+ +P I + +G+ F N W
Sbjct: 45 TGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFS-NGSWNGI 103
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
D RGK LY+ A+LIE+D + +A +E+ DNG + + + + ++ ADKI
Sbjct: 104 DPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSSRGDVDLVINYLKSSAGFADKID 163
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G I T FSYT +QP+GVCG I+PWN P+LM+ K+ AL G TVV+K AE TPL+
Sbjct: 164 GRMIDTGRTHFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLS 223
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+AGIP GV+NIV GFG+ G A+T+HP + K++FTGS G+ I ++A
Sbjct: 224 ALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAAAG 283
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
LK+VTLELGGKSP I+ DA+L A+ G++++ G++C A SR+YV+ IYDKF++
Sbjct: 284 -LKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIE 342
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
+++I+VG+PFDEST G Q + +NK+L ++ GK EGA L+ GGER+G+ GY+
Sbjct: 343 EFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYF 402
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
I+PTVF DV +DM I KEEIFGPV ++ KF + +EVI+ AN++ YGLAAGI T+N+N AL
Sbjct: 403 IKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTAL 462
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ + V AGTVW+N Y H PFGGF SG+GRE + A++ YL+ K V
Sbjct: 463 KVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAV 513
>UniRef50_A2RH33 Cluster: Aldehyde dehydrogenase; n=21; cellular
organisms|Rep: Aldehyde dehydrogenase - Bacillus
amyloliquefaciens
Length = 519
Score = 440 bits (1085), Expect = e-122
Identities = 226/477 (47%), Positives = 299/477 (62%), Gaps = 7/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KL+ID ++V + G TF T +P G + + + Q F + EWR
Sbjct: 45 KLYIDGKFVPSTSGSTFVTPNPATGETLMTLYEAQSEDIDSAVKAARKAFD-HGEWRTMP 103
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP---DSVRYLGSLADK 125
A+ R +L+YK ADL+E LA+LE+ DNG IP + +RY + K
Sbjct: 104 AASRSRLMYKLADLMEEHKTELAQLETLDNGKPINETTN--GDIPLAIEHMRYYAGWSTK 161
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
I G TIP G F+YT +PVGV G I+PWN P+LM + K+ ALA GCT+V+KPAEQTP
Sbjct: 162 ITGQTIPVAGSYFNYTRHEPVGVVGQIIPWNFPLLMAMWKMGAALATGCTIVLKPAEQTP 221
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AG P GV+NIVPGFGE AG ALT+H DV K++FTGS E+GK I + A
Sbjct: 222 LTALYLAELIDQAGFPDGVINIVPGFGETAGEALTNHDDVDKLAFTGSTEIGKKIMEKAA 281
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+KRVTLELGGKSP II+ DA+L AIP A +GV F+QGQ+C A SR+++ YD+
Sbjct: 282 -KKIKRVTLELGGKSPNIILPDANLKKAIPGALNGVMFNQGQVCCAGSRVFIHKDKYDEV 340
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
V V YAK+++ G + T GP + + +VL IE GK EGA +AGG G
Sbjct: 341 VSEMVSYAKSLQQGAGLHQDTQIGPLVSQEQHERVLSYIEKGKAEGAKAVAGGSCPFEEG 400
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y++ PTVFADV+D MTIAKEEIFGPV + + +DT++EVI+RAN + YGLAAG++T N+ N
Sbjct: 401 YFVSPTVFADVDDSMTIAKEEIFGPVLAAIPYDTVDEVIERANRSEYGLAAGLWTENVKN 460
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + ++AGTVWVN Y +PFGG+K SG+GRE G A+ Y E K+V I+L
Sbjct: 461 AHYIADRLQAGTVWVNCYNVFDAASPFGGYKQSGLGREMGSYALNNYTEVKSVWINL 517
>UniRef50_O75891 Cluster: 10-formyltetrahydrofolate dehydrogenase;
n=78; cellular organisms|Rep: 10-formyltetrahydrofolate
dehydrogenase - Homo sapiens (Human)
Length = 902
Score = 433 bits (1068), Expect = e-120
Identities = 222/477 (46%), Positives = 299/477 (62%), Gaps = 8/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 423 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIS 481
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 482 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 541
Query: 128 GDTIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G TIP + + + T K+PVGVCG+I+PWN P++M K LAAG TVV+KPA+
Sbjct: 542 GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 601
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT +AGIPKGVVN++PG G G L+ HPDV KI FTGS EVGK I K+
Sbjct: 602 TPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+N+K+V+LELGGKSPLII D DLN A+ S VFF++G+ C+AA RL+V+ I+D
Sbjct: 662 CAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHD 721
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PTVF DV D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT
Sbjct: 782 PGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTR 841
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL S ++AGTV+VN Y APFGGFK SG G++ G A+ YL KTV
Sbjct: 842 DINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>UniRef50_Q25417 Cluster: Aldehyde dehydrogenase, mitochondrial
precursor; n=4; Leishmania|Rep: Aldehyde dehydrogenase,
mitochondrial precursor - Leishmania tarentolae
(Sauroleishmania tarentolae)
Length = 498
Score = 425 bits (1047), Expect = e-117
Identities = 212/481 (44%), Positives = 297/481 (61%), Gaps = 6/481 (1%)
Query: 1 MVPEIKYT--KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXF 58
M P++ + KL I+ ++V A G+TF+ +P D VIA VA+ + F
Sbjct: 11 MAPKVTHIQEKLLINGKFVPAVSGKTFEVVNPADEKVIANVAEAEKADVDLAVKAARHAF 70
Query: 59 QRNSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVR 117
+ +R+ D R L+ + AD++E++ + +A LES DNG Y+ L + + + R
Sbjct: 71 E---SFRMTDCQWRRNLMLRLADILEKNSKEMAALESLDNGKPYEVALNVDVALSVECFR 127
Query: 118 YLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
Y LADK+ G P G+ +QP+GVCG I+PWN P+LM K+ ALA G TVV
Sbjct: 128 YCAGLADKVNGTVPPRSGNFLGIVKRQPIGVCGQIIPWNFPLLMAAFKLSPALAMGNTVV 187
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
+KPAEQTPLT EAG P GV+NI+PGFG AG + H DV KI+FTGS VG
Sbjct: 188 LKPAEQTPLTAVRLGEMVMEAGYPDGVLNILPGFGATAGSEIARHMDVDKIAFTGSTAVG 247
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
+ + A NLK+V+LELGGKS LI+ DADL A A + V+F+ GQ+C A+SR+YV
Sbjct: 248 HQVMQMAAETNLKKVSLELGGKSALIVCEDADLEEAAEVATTRVYFNTGQVCTASSRIYV 307
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
+YD+FV + A+A +VG D GP + + +VLG IE G K GA ++ G
Sbjct: 308 HESVYDEFVSRLRKNAEARKVGPGNDTGNNMGPLVSKKQHERVLGYIEDGVKAGATVVTG 367
Query: 358 GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G++IG GY++QPT+F+DV +DM I KEEIFGPV ++K+ ++EV+ RAN++ YGLAAG
Sbjct: 368 GKKIGDKGYFVQPTIFSDVKEDMRICKEEIFGPVTCVMKYKDMDEVVKRANDSIYGLAAG 427
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
I T +++ AL++S ++ AGTVWVN + PFGGFK SGIGRE G + V+ Y E K
Sbjct: 428 ICTRSMDTALRYSTYLNAGTVWVNTWNNFCPSMPFGGFKQSGIGRELGKEVVDMYTEPKA 487
Query: 478 V 478
+
Sbjct: 488 I 488
>UniRef50_Q4TBF9 Cluster: Chromosome undetermined SCAF7131, whole
genome shotgun sequence; n=2; Deuterostomia|Rep:
Chromosome undetermined SCAF7131, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1002
Score = 422 bits (1040), Expect = e-117
Identities = 209/477 (43%), Positives = 299/477 (62%), Gaps = 8/477 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ + DA+ G+T++T +P DGSVI V+ + N W +
Sbjct: 525 FINGRFEDAESGKTYNTVNPSDGSVICNVSYASVGDVDRAVAAAKEAYD-NGPWGKMNPR 583
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQGD 129
RG LLY+ ADL+E E LA +E+ D+G VY L+ G+ + RY DKIQG
Sbjct: 584 DRGSLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGK 643
Query: 130 TIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
TIP + + ++T K+P+GVC +++PWN P++M K LAAG T+V+KPA+ TP
Sbjct: 644 TIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTP 703
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AGIPKGV+NI+PG G G L+ HPDV K+ FTGS +GK I K+
Sbjct: 704 LTALKFAELSVKAGIPKGVINILPGSGGMVGQRLSEHPDVRKLGFTGSTPIGKQIMKSCA 763
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLK+V+LELGGKSPLII D D++ A+ S V+F++G+ C+AA RL+V+ I+D+F
Sbjct: 764 VSNLKKVSLELGGKSPLIIFRDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEF 823
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
+ VE K +++G+P D ST +GPQ ++ ++K+L E G KEGA L+ GG ++ G
Sbjct: 824 ISRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCEVGVKEGATLVYGGRQVDRPG 883
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFD--TLEEVIDRANNTNYGLAAGIFTTNL 423
++++PTVF DV D M IAKEE FGPV + KF +E V+ RAN+T YGLA+G+FT ++
Sbjct: 884 FFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFQDGDVEGVLQRANDTEYGLASGVFTRDI 943
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
N A+ S+ +EAGTV+VN Y +PFGGFK SG G++ G A+ YL+ K V +
Sbjct: 944 NKAMYVSERLEAGTVFVNTYNKTDVASPFGGFKQSGFGKDLGEDALMEYLKTKAVTV 1000
>UniRef50_Q4SUU7 Cluster: Chromosome undetermined SCAF13842, whole
genome shotgun sequence; n=4; Tetraodontidae|Rep:
Chromosome undetermined SCAF13842, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 437
Score = 418 bits (1029), Expect = e-115
Identities = 220/433 (50%), Positives = 275/433 (63%), Gaps = 23/433 (5%)
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKI 126
DAS RG LL + AD IE+D YLA+LE+ DNG Y + L + +RY ADK
Sbjct: 2 DASHRGLLLSRLADAIEKDSAYLAELETLDNGKPYAVAYAVDLPNVVKCLRYYAGWADKW 61
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
+G TIP DGD F YT +PVGVCG I+PWN P+LM K+ ALA G TVV+K AEQTPL
Sbjct: 62 EGKTIPIDGDFFCYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNTVVMKVAEQTPL 121
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +E G P+GVVNI+ G G AG A+ H D+ K++FTGS EVG +IQ+A+G+
Sbjct: 122 TALYVANLVREVGFPEGVVNILAGMGPTAGAAIARHSDIDKVAFTGSTEVGHMIQQASGS 181
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLA-----IPYAG-----------------SGVFFH 284
+NLK+VTLELGGKSP II++DAD P AG S
Sbjct: 182 SNLKKVTLELGGKSPNIILSDADSRCCPRRSPNPSAGLTHLRCPQWRTPWSSPTSPCSST 241
Query: 285 QGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLI 344
+ C A SR YVQ +YD+FV+ +VE AK VG+PFD T GPQ+D NK+LG I
Sbjct: 242 RASRCCAGSRTYVQEDVYDEFVQRSVERAKRRLVGDPFDLKTEQGPQVDLEQFNKILGYI 301
Query: 345 ETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVI 404
TGK+EGA L+ GG GY+IQPTVF DV D+M IA+EEIFGPV I+KF +LEEV+
Sbjct: 302 STGKREGAKLMCGGGAAADKGYFIQPTVFGDVQDNMAIAREEIFGPVMQIMKFKSLEEVL 361
Query: 405 DRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGREN 464
+RAN+T YGLAA +FT +++ A S + AGTVW+N Y QAPFGG+K SGIGRE
Sbjct: 362 ERANDTKYGLAAAVFTKDIDKAHYISAGLRAGTVWINCYDVFGSQAPFGGYKASGIGREL 421
Query: 465 GIKAVEAYLEEKT 477
G ++ Y E KT
Sbjct: 422 GEYGLDNYTEVKT 434
>UniRef50_Q2UGV3 Cluster: Aldehyde dehydrogenase; n=9;
Ascomycota|Rep: Aldehyde dehydrogenase - Aspergillus
oryzae
Length = 502
Score = 416 bits (1025), Expect = e-115
Identities = 217/484 (44%), Positives = 294/484 (60%), Gaps = 10/484 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI+NE+V +K GE F T +P D IA V F ++ W+L
Sbjct: 22 LFINNEFVPSKSGEKFATINPADEKEIASVYAAGEEDIDIAVKAARKAF-KDPSWKLLPP 80
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
+ RG L+ K ADLIE+ E LA +E++DNG Y L L + +++RY ADK+ G
Sbjct: 81 TDRGALMLKLADLIEQHREILATIETWDNGKPYSVSLSSDLGEVINTLRYYAGWADKVHG 140
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
TI T D +YTL+QP+GV G I+PWN P+ M K+ ALA G T+V+KPAEQTPL+
Sbjct: 141 QTISTTPDKLAYTLRQPIGVVGQIIPWNFPLAMAAWKLGPALACGNTIVMKPAEQTPLSI 200
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK-AAGTN 247
KEAG P GV+NIV G G AG AL HPDV K++FTGS G+ + K AAGT
Sbjct: 201 LYLATLIKEAGFPPGVINIVNGLGRVAGSALVTHPDVDKVAFTGSTLTGREVMKLAAGT- 259
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
LK +TLE GGKSPL++ DAD+ A +A G+ ++QGQ+C A SR+ V IYDKF++
Sbjct: 260 -LKNITLETGGKSPLVVFGDADIEQAAKWAHIGIMYNQGQVCTATSRILVHESIYDKFIE 318
Query: 308 -GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE---RIGT 363
E A +VG+PF + T GPQ+ ++ ++VL IE GK EGA L+AGGE +G
Sbjct: 319 LFKQEVASVSKVGDPFADDTFQGPQVTKAQYDRVLSYIEAGKSEGATLVAGGEPYKNVGD 378
Query: 364 A-GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G++I PT+F +V D+M I +EE+FGP I F +E + RAN+T YGL A IFT +
Sbjct: 379 GKGFFIAPTIFTNVKDNMRIYREEVFGPFVVISSFAAEDEAVTRANDTTYGLGAAIFTKD 438
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ A + + +EAG VW+N+ + PFGG K SGIGRE G +EAY + K + ++L
Sbjct: 439 IERAHRVASEIEAGMVWINSSNDSDFRVPFGGIKQSGIGRELGEAGLEAYSQVKAIHVNL 498
Query: 483 PKKL 486
KL
Sbjct: 499 GSKL 502
>UniRef50_A7RQR3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 874
Score = 409 bits (1006), Expect = e-112
Identities = 204/479 (42%), Positives = 299/479 (62%), Gaps = 8/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI+ E+VD+ G+TF+T +P DG+V+A+V+ F N W +
Sbjct: 395 QLFINGEFVDSHHGKTFNTINPTDGTVLAQVSLATHEDVDDAVDAAKEAFY-NGPWGSMN 453
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A R L+ + ADL+E+ E LA +ES D+G VY L+ G+ D+VRY DKIQ
Sbjct: 454 ARDRATLMNRLADLMEQHKEELATIESLDSGAVYTLALKTHVGMSIDTVRYFAGWCDKIQ 513
Query: 128 GDTIPTDGD----SFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G T+P + + YT ++P+GVCGLI+PWN P++M K+ LAAG TVV+KPA+
Sbjct: 514 GLTVPVNNAKPNRNLCYTKREPIGVCGLIVPWNYPLMMLAWKISPLLAAGNTVVLKPAQV 573
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP+T AG PKGV+NI+PG G G + HPDV K+ FTGS VGK I ++
Sbjct: 574 TPMTALKFAELAARAGFPKGVINILPGSGSVVGNRICEHPDVRKLGFTGSTPVGKAIMES 633
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
T+NLK+ +LELGGKSPLII +D D+ A+ F++G+ C+AA RL+V+ I+D
Sbjct: 634 CATSNLKKCSLELGGKSPLIIFSDCDMERAVRQGMMACLFNKGENCIAAGRLFVEESIHD 693
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV V+ K +++G+P D +T +GPQ ++ ++ ++ ++ G +EGA L+ GG +
Sbjct: 694 EFVNRLVDELKKLKIGDPLDTATDHGPQNHKAHLDSLVEYVKRGVEEGAKLVYGGRHLDR 753
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFD--TLEEVIDRANNTNYGLAAGIFTT 421
G++ +P VF +V DDM IAKEE FGPV I KFD +E V++ AN T YGLA+G+FT
Sbjct: 754 PGFFFEPAVFTNVEDDMFIAKEESFGPVVIISKFDDGDVEGVLESANGTEYGLASGVFTK 813
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+++ AL+ + +EAGT +VN Y APFGG K SG G++ G++A+ YL+ K + I
Sbjct: 814 DMSKALRVADALEAGTCFVNTYNKTDVAAPFGGCKQSGFGKDLGMEALNEYLKTKVITI 872
>UniRef50_Q0SCV0 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|Rep:
Aldehyde dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 495
Score = 403 bits (993), Expect = e-111
Identities = 217/486 (44%), Positives = 291/486 (59%), Gaps = 8/486 (1%)
Query: 2 VPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRN 61
+P+ T+LFI +W A DG TF +P G + V+ G Q N
Sbjct: 13 LPDGAATQLFIGGQWRPASDGGTFTDLNPATGKPLVDVSAGTAQDIDDAVRAART--QLN 70
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLG 120
EW + RG++L K ADLIERD E LA+LE+ D G V + + + + R+
Sbjct: 71 GEWGSLPGAARGRILNKVADLIERDGEILARLEALDVGKPVGQPTMLDIPMAAGTFRHFA 130
Query: 121 SLADKIQGDTIPTDG----DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTV 176
ADKI G +IPT G + SYT+++PVGV G I+PWN P+++ K+ ALAAG T+
Sbjct: 131 GWADKITGQSIPTAGYFGQPTHSYTVREPVGVIGAIVPWNTPLMISAWKIAPALAAGNTL 190
Query: 177 VVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEV 236
VVKP E PL+ +EAG+P G VNIVPG GE AG AL HP V KISFTGS V
Sbjct: 191 VVKPPEDAPLSILHLATLLEEAGLPAGTVNIVPGLGEVAGDALAGHPGVDKISFTGSPRV 250
Query: 237 GKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
G++I K A + KR TLELGGKSP II+ DADL A+ G+FF+QG++C A +R+
Sbjct: 251 GRIIAKRAA-DTFKRTTLELGGKSPQIILPDADLEAAVGGTAMGLFFNQGEVCAAGTRIL 309
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
V +Y + V G A A +G+PFD +T G ++ + VLG IE G+ EGA ++A
Sbjct: 310 VHRSLYSQVVDGLAAAASAQVLGDPFDPATTMGALVNAKQRDTVLGYIEAGRSEGARVVA 369
Query: 357 GGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
GG R G+++QPT+FAD N+DM IA+EEIFGPV +++ FDT +E I AN T+YGLAA
Sbjct: 370 GGGRPDGDGFFVQPTIFADANNDMKIAREEIFGPVGTVIAFDTTDEAIAIANATDYGLAA 429
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
I+T ++++A + V AG V VN + + P+GG K SG GRE G +EA EEK
Sbjct: 430 SIWTRDVSHAHTLAGKVRAGAVAVNGWAPIDPALPWGGMKTSGTGRELGWAGIEANTEEK 489
Query: 477 TVIISL 482
V I L
Sbjct: 490 VVTIIL 495
>UniRef50_O74187 Cluster: Aldehyde dehydrogenase; n=42; cellular
organisms|Rep: Aldehyde dehydrogenase - Agaricus
bisporus (Common mushroom)
Length = 500
Score = 403 bits (992), Expect = e-111
Identities = 198/481 (41%), Positives = 296/481 (61%), Gaps = 4/481 (0%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL- 66
T LFI+ E+VD T D +P +G +I K+++ F+ + W L
Sbjct: 22 TGLFINGEFVDGVKNTTIDVVNPANGKLITKISEATEADIDIAVEAAHKAFE--TTWGLN 79
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADK 125
S+RG +LYK A L+E++ + L+ +E+ DNG + + LS ++++ ADK
Sbjct: 80 CSGSKRGDMLYKLAQLMEKNIDDLSAIEALDNGKTFLWAKSVDLSLSISTIKHYAGWADK 139
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
G I TD +Y+ +P+GV G I+PWN P+LM K+ ALA G +V+KP+E TP
Sbjct: 140 NFGQVIETDEKKLTYSRHEPIGVVGQIIPWNFPLLMLAWKIGPALATGNCIVLKPSEFTP 199
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L+ +EAG P GVVN+V G+G G A++ H + K++FTGS VG+ + +AA
Sbjct: 200 LSALRMCALIQEAGFPPGVVNVVTGYGSTTGQAISSHMKIDKVAFTGSTLVGRKVMEAAA 259
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLK VTLELGGKSP++I +DADL ++ + G+F++ GQ C A +R++VQ GIYDKF
Sbjct: 260 KSNLKNVTLELGGKSPVVIFDDADLEQSVNWTAHGLFWNHGQACCAGTRIFVQEGIYDKF 319
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
++ + K I++G+PF GPQ+ + ++++ IE+G+ EGA + GGER G G
Sbjct: 320 LQKFTDKIKEIKLGDPFGLGIDQGPQVSQIQYDRIMSYIESGRAEGATVHVGGERHGNEG 379
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y+IQPT+F D DM I KEEIFGPV +++KF +EVI +AN++NYGLAA +F+ ++N
Sbjct: 380 YFIQPTIFTDTTPDMKIVKEEIFGPVGAVIKFKDGKEVIKQANDSNYGLAAAVFSQDINK 439
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
A++ + +AGT WVN T+ PFGG+K SGIGRE G A+ Y K V ++L K
Sbjct: 440 AIETAHAFKAGTAWVNCANTIDAGVPFGGYKQSGIGRELGEYALHNYTNVKAVHVNLNWK 499
Query: 486 L 486
+
Sbjct: 500 M 500
>UniRef50_Q89NQ8 Cluster: Betaine aldehyde dehydrogenase; n=4;
Proteobacteria|Rep: Betaine aldehyde dehydrogenase -
Bradyrhizobium japonicum
Length = 495
Score = 402 bits (990), Expect = e-110
Identities = 203/474 (42%), Positives = 289/474 (60%), Gaps = 4/474 (0%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L ID V A G TF + +P G VIA VA+G F+ WR A
Sbjct: 23 LLIDGRRVPASSGRTFKSLNPATGQVIATVAEGNEADVDHAVAAARRAFE--GPWRTMRA 80
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
S+RG++L ++A+L++ + E + +LES D G LR D++ Y ADKI G
Sbjct: 81 SERGQILLRWAELLKANAEEIIELESIDAGKPISATLRQDFPAAVDTLIYYAGWADKISG 140
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
D +P D+ +YT+++PVGV I+PWN P+++ + K+ ALA GCT+V+KPAE T L+
Sbjct: 141 DVVPVRDDALTYTVREPVGVVAAIVPWNFPLMIGMWKLAPALACGCTIVMKPAELTSLSA 200
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+AG+P GV N+V G G G AL +HPDV K++FTGS VG+ I K A N
Sbjct: 201 LRIAELALQAGLPAGVFNVVTGPGRVVGDALVNHPDVDKVTFTGSPGVGRGIMKGAA-GN 259
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
KRV+LELGGKS +I +DADL A A SG+FF+ GQ+C A SR+ VQ YD+ V+
Sbjct: 260 FKRVSLELGGKSANVIFDDADLEAASKAAASGIFFNAGQVCSAGSRVLVQEKAYDEVVER 319
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYI 368
AK++++G+P D T GP I E M +L ++ G+KEGA+L+ GG R+G GY+I
Sbjct: 320 LAARAKSLKIGDPLDRKTALGPVISEKQMKSILDYVDIGQKEGASLVTGGTRVGERGYFI 379
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
P VFA+V +M I++EEIFGPV SI+KF + + AN T Y LAAG+++ ++ +
Sbjct: 380 SPAVFANVEHEMRISQEEIFGPVVSIIKFRDEADALRIANGTAYSLAAGVWSRDIGKLQR 439
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
F+K AGTVW+N Y + P+GG +DSG+GRE+G A++ + E K V ++L
Sbjct: 440 FAKRARAGTVWMNTYGYTDVRLPWGGERDSGLGREHGTAALDNFTEPKAVWMNL 493
>UniRef50_Q5KW79 Cluster: NAD-dependent aldehyde dehydrogenase; n=5;
Bacteria|Rep: NAD-dependent aldehyde dehydrogenase -
Geobacillus kaustophilus
Length = 498
Score = 402 bits (990), Expect = e-110
Identities = 217/481 (45%), Positives = 292/481 (60%), Gaps = 11/481 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L+ID EW A GE FD P G V A+VA F + W
Sbjct: 13 LWIDGEWRPAASGERFDVIDPATGEVTARVANAGEDDVDAAVAIAEEAFS-DRRWLAISP 71
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
+RG++L + A+LI + LA+L + +NGM L I + D + SL K QG
Sbjct: 72 LERGRILRRIAELIRQHHCELAQLMTRENGMPINLALFIEIPLAADCFDFFASLVVKPQG 131
Query: 129 DTIP-----TDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ +P + D ++T+K+P+GV GLI PWN P+LM K+ ALAAGCT+VVKPA +
Sbjct: 132 EVLPFSVAGSAPDYMAWTMKEPIGVAGLITPWNFPLLMPTWKIAPALAAGCTMVVKPAPE 191
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT EAG+P+GV+N++PG E AG AL HP V KI+FTG E G+ I +A
Sbjct: 192 TPLTALKLAEICHEAGVPEGVINVLPGLDE-AGKALVRHPRVPKIAFTGETETGRHILQA 250
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A + +KRVTLELGGKSP II DADL A A GVF++ GQ+C A SR+ V+ +Y+
Sbjct: 251 AAPH-IKRVTLELGGKSPNIIFADADLEQAAKSALFGVFYNSGQVCQAGSRILVERTVYE 309
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI-- 361
FV+ E AK ++VG + + GP I KVL IE GK+EGA L AGG +
Sbjct: 310 PFVERLAERAKKLKVGPGTNPRSDLGPVISREQYEKVLRYIEIGKQEGARLAAGGRALDG 369
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G GY+I+PTVFADV+ M IA EEIFGPV +++ F EE + AN T YGLAA ++T
Sbjct: 370 GGGGYFIEPTVFADVSPSMRIACEEIFGPVAAVIPFADEEEAVRIANGTMYGLAAAVWTN 429
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
++ AL+ ++ V++GTVW+N Y ++ APFGG+K SG+GRE G++A++AYLE KTVI
Sbjct: 430 DIKRALRLARRVKSGTVWLNTYQVLSPTAPFGGYKQSGLGRELGMQALDAYLETKTVICD 489
Query: 482 L 482
L
Sbjct: 490 L 490
>UniRef50_Q54IU0 Cluster: Aldehyde dehydrogenase; n=1; Dictyostelium
discoideum AX4|Rep: Aldehyde dehydrogenase -
Dictyostelium discoideum AX4
Length = 503
Score = 400 bits (986), Expect = e-110
Identities = 206/487 (42%), Positives = 297/487 (60%), Gaps = 14/487 (2%)
Query: 8 TKLFIDNEWVDAKD-GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
TK+FI+NEWVD+ D E F +P + + + G + +W
Sbjct: 17 TKIFINNEWVDSIDCNENFSLINPTNEECLGIIGLGGRKDVDRAVEAARSAIR--GKWST 74
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADK 125
RG LL K AD +E E +A +ES + G + ++ + L +RY ADK
Sbjct: 75 MAPLDRGILLNKLADKLEEKREQMATIESINVGKPIGESLVYDLKQSITFLRYFAGWADK 134
Query: 126 IQGDTIPTDGDS---------FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTV 176
I G TIP S +YT + P+GVC LILPWN P+ + + K+ ALAAG TV
Sbjct: 135 ITGRTIPISSSSDTSTPTRQVLAYTKQVPLGVCALILPWNFPLQLLMFKLAPALAAGNTV 194
Query: 177 VVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEV 236
++KP+E TPL+ KE G P GVVN+V G G G A++ H + KI FTGS +V
Sbjct: 195 IIKPSEFTPLSTFYLAELIKEVGFPPGVVNVVCGLGSVVGDAMSSHMKINKIGFTGSTKV 254
Query: 237 GKLIQKAAGTNNLKRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRL 295
GK++Q +A +NLK +LELGGKSP+II ND DL+LA+ ++ G+F++ GQ C AASR+
Sbjct: 255 GKMVQNSATNSNLKHCSLELGGKSPIIIFNDVEDLDLAVIHSFHGLFWNAGQCCSAASRI 314
Query: 296 YVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLL 355
YVQSGIYD+FV+ + ++ +G+P + T GPQ+++ +L IETGK+EGA L+
Sbjct: 315 YVQSGIYDQFVEKIKKQVESRVLGDPLSKDTHQGPQVNKFQFESILRYIETGKREGATLV 374
Query: 356 AGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLA 415
GG+R G GYYI+PTVF++V D MTIA+EEIFGPV SIL+F+T++E IDRAN++ +GL
Sbjct: 375 CGGKRFGNKGYYIEPTVFSNVTDVMTIAREEIFGPVMSILRFETVQEAIDRANDSEFGLV 434
Query: 416 AGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEE 475
+FT ++N ++ S V++G VWVN++ + P+GGFK SG GR+ + + E
Sbjct: 435 GAVFTKDINKSIIVSDQVQSGLVWVNSFNIIDPSIPWGGFKSSGKGRDASEYCLSVWTET 494
Query: 476 KTVIISL 482
KT ++ +
Sbjct: 495 KTTVLDV 501
>UniRef50_Q39P13 Cluster: Aldehyde dehydrogenase; n=1; Burkholderia
sp. 383|Rep: Aldehyde dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 503
Score = 396 bits (975), Expect = e-109
Identities = 212/483 (43%), Positives = 280/483 (57%), Gaps = 7/483 (1%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P +Y L+ID WV DGE ++ P G A G F +
Sbjct: 13 PLRRYEHLYIDGAWVKPIDGELAESIDPATGQPWAIAPMGGPQDIDRAVEAARTAF--HG 70
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
WR R LL + ADL LA +ES DNG + + L+ ++ SL
Sbjct: 71 TWRSTPGHVRAALLRRLADLFSAAIPELAIIESRDNGNLVREHRASLTAQVQWYQWFASL 130
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADK QG TIP D ++T + P+GV G I+PWN P+L KV ALAAGCTVVVKPAE
Sbjct: 131 ADKAQGATIPIDDSVHAFTTRVPIGVVGAIIPWNAPLLATCLKVGAALAAGCTVVVKPAE 190
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTP++ EAG P GV N+VPG+G AG L HPDV KISFTG+ + K + +
Sbjct: 191 QTPVSALELARLVHEAGFPPGVFNVVPGYGRTAGAHLVKHPDVNKISFTGASQTAKHMVR 250
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
G +NLKR T ELGGK+P I+ DADL+ AI A + + GQ C SR+ V+ IY
Sbjct: 251 -DGADNLKRFTFELGGKAPHILFADADLDNAINAATASAWRLTGQSCALGSRVLVERPIY 309
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+ V+ AKA+RVG P +S GPQ E+ + K L ++ GK++GA L+ GG RI
Sbjct: 310 DRVVEAFRTRAKAVRVGLPSIDSNHMGPQSHETQLAKTLSYVDAGKQDGAELVTGGRRIT 369
Query: 363 T----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
T AGY+++PTVFA V + M IA+EEIFGP+ S++ FD +E I AN+T YGL AG+
Sbjct: 370 TPELAAGYFVEPTVFAGVTNQMRIAREEIFGPIASLIPFDGEDEAIAIANDTPYGLTAGL 429
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+T ++ A + S ++AG VWVN Y + P+GGFK SG GRENGI A++ YLE +T
Sbjct: 430 WTRDVGRAHRVSNRIDAGMVWVNTYSFLRWSTPYGGFKASGWGRENGIDALDPYLETRTT 489
Query: 479 IIS 481
+IS
Sbjct: 490 VIS 492
>UniRef50_Q9URW9 Cluster: Aldehyde dehydrogenase; n=20;
Ascomycota|Rep: Aldehyde dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 496
Score = 394 bits (971), Expect = e-108
Identities = 208/480 (43%), Positives = 291/480 (60%), Gaps = 9/480 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L+I+ EW K ET++T P VIAKV F+ W+
Sbjct: 23 LYINGEW--HKSAETWETVDPSIEEVIAKVYLAGEKEIDYAVKSAKEAFKT---WKKVPG 77
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADKIQG 128
S++G+LL K A+L E+ + LA +E+ D+G + N + G +RY ADKI G
Sbjct: 78 SEKGELLMKLAELTEKHADTLAAIEAMDSGKPLVSNARGDVDGTIALLRYCAGWADKIYG 137
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
IPT + +Y + P+GVCG I+PWN P+ M K+ ALAAG +++K AE TPL+
Sbjct: 138 QVIPTGPEKLAYAKRTPIGVCGQIVPWNYPLNMAGWKIAPALAAGNCIIIKSAETTPLSL 197
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+EAG PKGVVNI+ G G AG + HP + KI+FTGS +VG ++Q+ A +N
Sbjct: 198 LYFATLVEEAGFPKGVVNIISGLGTVAGSYMAKHPGIDKIAFTGSTKVGVIVQQLA-ASN 256
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LK VTLE GGKSP ++ DADL+ A+ +A G+ ++ GQIC + SR+YVQ +YDKF++
Sbjct: 257 LKAVTLECGGKSPFLVFEDADLDQAVKWAALGIMYNSGQICTSNSRIYVQDSVYDKFIEL 316
Query: 309 AVEYA-KAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-TAGY 366
++ + VG PFD++TV GP ++++ N++ IE GKKEGA L+ G E + GY
Sbjct: 317 FKKHVIQDYIVGMPFDDNTVVGPVVNKTQYNRIKNYIEQGKKEGAKLVLGDEPLPLKQGY 376
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+I PT+FAD +++MTI KEEIFGPV +I KF T +E I++ANNT YGLAA FT +L A
Sbjct: 377 FISPTIFADCSENMTIVKEEIFGPVVAISKFKTEDEAIEKANNTTYGLAAMCFTKDLERA 436
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
+ S +EAG V++N+ QAPFGG K SGIG E G +E Y + K V I+ KL
Sbjct: 437 HRVSDELEAGMVFINSTENSDIQAPFGGIKMSGIGNELGSNGIEMYTQIKAVHINFNNKL 496
>UniRef50_Q1AVQ5 Cluster: Betaine-aldehyde dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Betaine-aldehyde
dehydrogenase - Rubrobacter xylanophilus (strain DSM
9941 / NBRC 16129)
Length = 503
Score = 387 bits (952), Expect = e-106
Identities = 196/481 (40%), Positives = 281/481 (58%), Gaps = 5/481 (1%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
+ KLFI NEW + G+TF+T P VIA + +G F N WR
Sbjct: 9 HPKLFIANEWRPSHTGQTFETVDPSTEEVIASIPRGGAEDVDEAVSAAREAF--NGPWRR 66
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKI 126
R + LY+ A +E E A+LE+ D G ++ + Y ADKI
Sbjct: 67 LTPEDRARFLYQVARSLESRLEEFARLETLDTGKPLQHSRNEIRNCVRYFDYYAGAADKI 126
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G+TIP + YT+++P+GV I+PWNVP+ M + ALAAG VVKPAEQTPL
Sbjct: 127 HGETIPLGPNYLDYTVREPLGVTAHIVPWNVPLGMVCRSLAPALAAGNAAVVKPAEQTPL 186
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T E P GV N+V GFGE+AG AL+ HP + I+FTGS+E G+ + +AA
Sbjct: 187 TALKLAELFLELDAPPGVYNVVTGFGEEAGRALSEHPGIDSITFTGSVETGRAVLRAA-A 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+++ V LELGGKSP ++ D DL+ A G++ + GQ C A SRL + I + F+
Sbjct: 246 EHVRPVVLELGGKSPQVVFADCDLDFAADEVAKGIYSNSGQYCDAGSRLLIDGSIKEPFL 305
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-TAG 365
+ +E A+AI++G DE + GP + E +VLG IE G KEGA +L GG G G
Sbjct: 306 EKVIERARAIKLGAGMDEPDM-GPLVSEEHFKRVLGYIEVGNKEGARMLTGGRAEGFERG 364
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y++ PT+F +V +M IA+EEIFGPV + L F + E I+ AN+++YGLAAGIFT +++
Sbjct: 365 YFVAPTIFDEVESNMRIAQEEIFGPVLATLSFGSEVEAIEIANDSSYGLAAGIFTRDIDR 424
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
AL+F+ ++AG V +N Y + +PFGG+K SGIGRE G+ A++ Y + K V++ + ++
Sbjct: 425 ALRFASEIQAGYVMINEYFSGGMGSPFGGYKQSGIGRERGLIALDNYTQIKNVVVKVGQR 484
Query: 486 L 486
L
Sbjct: 485 L 485
>UniRef50_Q0SDT3 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|Rep:
Aldehyde dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 502
Score = 386 bits (950), Expect = e-106
Identities = 202/483 (41%), Positives = 284/483 (58%), Gaps = 11/483 (2%)
Query: 8 TKLF-IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
TK F + +WV++ GETF+T P G V+ VA+G F W
Sbjct: 23 TKRFLVGGQWVESASGETFETIDPATGQVLTTVARGGAEDVDRAVRAARTAFDEGP-WAT 81
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADK 125
++R +L+++ D++ E +LE+ DNG + ++ D RY A K
Sbjct: 82 MKPNERERLIWRVGDILSERAEEFGQLEALDNGKSAGIAAAVDVAWSADIFRYFAGWATK 141
Query: 126 IQGDTIPTD------GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
I+G T+ G +YTL++PVGVCGLI+PWN P+LM K+ ALAAG TV++K
Sbjct: 142 IEGSTVNVSMPFVPGGQFHAYTLREPVGVCGLIVPWNFPLLMAAFKLAPALAAGNTVILK 201
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
PAEQTPLT +EAG P GVVNIV G+G DAG AL+ H DV KI+FTGS EVGK
Sbjct: 202 PAEQTPLTAILLGEVFEEAGFPPGVVNIVTGYG-DAGAALSAHDDVDKIAFTGSTEVGKK 260
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I AA NLK+V+LELGGKS ++ DAD + A+ + + F+ GQ CVA +R++V+
Sbjct: 261 IVDAA-RGNLKKVSLELGGKSANVVFADADFDAAVTGSLNAWLFNHGQCCVAGTRMFVED 319
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
I+D F E A +++G D +T GP + + +KV G + G +GA L GG+
Sbjct: 320 SIFDDFTAAVAEAASQVKIGPGLDPTTQLGPLVSQEQFDKVTGYLAAGLADGARALTGGK 379
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
R G G+Y++PTVF DV + +I +EEIFGPV + L F+ E V AN++ YGLAAGI+
Sbjct: 380 RWGDTGFYVEPTVFVDVKPEFSIVEEEIFGPVVAALPFNAEEGVAKAANSSIYGLAAGIW 439
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T +L+ A ++ ++AG+VW+N Y PFGG+K SG GRE G A++ Y + K V
Sbjct: 440 TKDLSKAHLTARQLKAGSVWINQYNGFDTAMPFGGYKQSGWGRELGATAIDLYTQTKAVN 499
Query: 480 ISL 482
I+L
Sbjct: 500 IAL 502
>UniRef50_Q0FK42 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Roseovarius sp. HTCC2601
Length = 502
Score = 384 bits (946), Expect = e-105
Identities = 204/479 (42%), Positives = 282/479 (58%), Gaps = 9/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI E V++ +G D P G VI+ VA F WR
Sbjct: 27 KLFIGGESVESVEGGRRDVVDPATGKVISNVADATANDVDLAVASARKAFD-GGVWRTTK 85
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
+R KLL++ A+LI++ LA+L++ D G Y ++G + RY A+KI
Sbjct: 86 PLERVKLLWRIAELIDKHAVQLAELDTLDEGSPYGVVKNGYIAGAAEHFRYFSGWANKIN 145
Query: 128 GDTIPTD--GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
GDT+P GD +YT ++PVGV ILPWNVP LM K+ ALAAGCTVVVKPAE TP
Sbjct: 146 GDTLPVSLPGDWHTYTTREPVGVVAQILPWNVPFLMMAWKLAPALAAGCTVVVKPAEDTP 205
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L+ +EAG+P+GVVNIV G G+ G AL H DV K+ FTGS G+ I + A
Sbjct: 206 LSAMLFAEICREAGVPEGVVNIVTGDGK-IGAALVDHADVDKVGFTGSTATGQAIVRGA- 263
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+ NLKRV+LELGGKSP+ + DAD++ AIP V+ + GQ C A +RLY+ +YD+
Sbjct: 264 SGNLKRVSLELGGKSPVFVFPDADIDAAIPQVAEAVYLNSGQACSAGTRLYIHEDVYDRV 323
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
++G Y++ +++G+ D +T GP I +V L++TG KEGA L+ GG G G
Sbjct: 324 IEGVAAYSETLKLGHGLDPATNMGPIISAKQFERVNRLLDTGLKEGAQLVTGG-NAGMDG 382
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDT--LEEVIDRANNTNYGLAAGIFTTNL 423
++++PT+ DV DM + +EEIFGPV S +K D+ +E + ANNT YGLAA I+T +L
Sbjct: 383 FFVKPTLLRDVTPDMCVYREEIFGPVISAMKIDSRNIEALALEANNTEYGLAASIWTNDL 442
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + + AGTVWVN + + +GGFK SG GRE G A++ Y E+KTV + +
Sbjct: 443 KLAHGLAGRIRAGTVWVNAHNMIDPSMGWGGFKQSGWGREMGRSAMDIYTEQKTVAMKI 501
>UniRef50_Q1LDQ8 Cluster: Aldehyde dehydrogenase; n=3;
Burkholderiales|Rep: Aldehyde dehydrogenase - Ralstonia
metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Length = 483
Score = 384 bits (944), Expect = e-105
Identities = 199/481 (41%), Positives = 282/481 (58%), Gaps = 5/481 (1%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P++ L ID + + GE +P IA VA+G +
Sbjct: 6 PDLPKHDLLIDGKRLPPGSGEYSTDINPATEEPIALVAQGSAADVDTAVLAARAALK--- 62
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
W A+ RG++L +FADL+E E L LES D G R L + D+VRY
Sbjct: 63 SWAGMRAADRGRILNRFADLLEAHAEELITLESLDAGKPLAAVRRQDLPAVVDTVRYYAG 122
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
DKI G IPT D+ +YT+++PVGV I+PWN P+++ + K+ ALA GCT++VKPA
Sbjct: 123 WCDKIHGAVIPTRPDALTYTVREPVGVVAAIIPWNFPLMIGMWKIAPALACGCTLIVKPA 182
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E TPLT EAG+P GV N+V G G G AL HP + K++FTGS VG+ I
Sbjct: 183 EITPLTALRVAELALEAGVPPGVFNVVTGKGSVVGNALVAHPGIDKVTFTGSPGVGRGIM 242
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
+ A +N KRVTLELGGKS +I DAD++ A A SG+FF+ GQ+C A SR+ Q +
Sbjct: 243 QGAASN-FKRVTLELGGKSANVIFADADIDAATRAAASGIFFNSGQVCSAGSRILAQRKV 301
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+ V+ A+AIRVG+P T GP + + M VL +E GK+EGA+ + GG RI
Sbjct: 302 YDEVVERLTTRARAIRVGDPASPDTTMGPVVSAAQMKTVLDYVEIGKREGASAVTGGARI 361
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++++PTVFA+V +M I++EEIFGPV S++ F+ E + AN T + LAAG+++
Sbjct: 362 GQRGFFVEPTVFANVEHEMRISQEEIFGPVASVIPFEDEAEAVRIANGTAFSLAAGVWSA 421
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
++ + + + AGTVW+N Y + P+GG DSG+GRE+G A+E + E K + +S
Sbjct: 422 DIARVHKVAGELRAGTVWINTYGYTDVRLPWGGAGDSGLGREHGDAAIENFTEPKAIWLS 481
Query: 482 L 482
L
Sbjct: 482 L 482
>UniRef50_A2QV34 Cluster: Similarity to indole-3-acetaldehyde
dehydrogenase Iad1 - Ustilago maydis; n=9;
Pezizomycotina|Rep: Similarity to indole-3-acetaldehyde
dehydrogenase Iad1 - Ustilago maydis - Aspergillus niger
Length = 500
Score = 381 bits (938), Expect = e-104
Identities = 200/479 (41%), Positives = 284/479 (59%), Gaps = 16/479 (3%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T LFI+NE+ A ET +P G+ +A V+ Q W+
Sbjct: 18 TTLFINNEFTPASTTETLTIENPSTGTPLATVSSASPADVDRAVHCAT---QALPAWKAT 74
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RYLGSLAD 124
+ RG LL+K ADLIERD E LA LE+ + G++Y + + + +P S+ RY AD
Sbjct: 75 PGAIRGTLLHKLADLIERDAEDLASLEALEGGLLYTDSMNM--SMPQSISTLRYYAGWAD 132
Query: 125 KIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
KI G T+ YT ++P+GVC I+PWN P+++ + K+ ALA G +++KP+E T
Sbjct: 133 KIDGKTLHLPDGGVGYTFREPLGVCAAIVPWNAPLMITIWKLAPALATGNCLIIKPSELT 192
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
PL+ +EAG P G V I+ G G AG AL+ HPD+ K+SFTGS G+ I A+
Sbjct: 193 PLSALKLALLIREAGFPAGTVAILLGDGPKAGNALSSHPDIRKLSFTGSTVAGRAILHAS 252
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
++NLK+++LELGGK P I+ +D DL A+ + G+ + GQIC A SR+YVQ GIYDK
Sbjct: 253 ASSNLKQISLELGGKGPSIVFSDCDLANALLWTRIGITANNGQICAAGSRIYVQRGIYDK 312
Query: 305 FVKGAVEYAKAIR-----VGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
F++ EYA+ R +G+ DE T GP + + K+LG +E GKK G +L GGE
Sbjct: 313 FLE---EYARLSREEKPVIGDALDEKTTKGPVSSAAQLQKILGYVEEGKKRGVRVLFGGE 369
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
RIG GY++Q T FADV + +EEIFGPV I FDT EE I AN++ +GL++ IF
Sbjct: 370 RIGEKGYFVQNTAFADVGQGEKMMREEIFGPVACIAPFDTEEEAIALANDSAHGLSSAIF 429
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
T ++N A + + +E+G V VN + +A APFGG K+SG GR+ G +A+E + K V
Sbjct: 430 TNDVNRAHRVTAGIESGQVTVNAWSMLAANAPFGGVKESGFGRDMGEEALEGWTTVKVV 488
>UniRef50_Q4ZZX2 Cluster: Aldehyde dehydrogenase; n=6;
Proteobacteria|Rep: Aldehyde dehydrogenase - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 499
Score = 379 bits (933), Expect = e-104
Identities = 202/478 (42%), Positives = 279/478 (58%), Gaps = 5/478 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+ FI E+ A GETFD SP DG ++AKVA F RLA
Sbjct: 23 RAFIQGEYTAASSGETFDCISPVDGRMLAKVASCDAADAQRAVDSARSAFNSGVWSRLAP 82
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQ 127
A ++ ++ +FA L+E++ E LA LE+ D G + L + + G ++ + G DK+
Sbjct: 83 AKRKATMI-RFAGLLEQNAEELALLETLDMGKPISDSLGVDIPGGARALSWSGEAIDKLY 141
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+ T D ++PVGV I+PWN P++M K+ AL+ G +V++KP+E++PLT
Sbjct: 142 DEVAATPHDQLGLVTREPVGVVAAIVPWNFPLMMACWKLGPALSTGNSVILKPSEKSPLT 201
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAGIP GV+N++PG+G G AL H DV + FTGS ++ K + AG +
Sbjct: 202 AIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMDVDTVVFTGSTKIAKQLMIYAGES 261
Query: 248 NLKRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N+KRV LE GGKSP I+ DA DL A A S + F+QG++C A SRL V+ I D+F+
Sbjct: 262 NMKRVWLEAGGKSPNIVFADAPDLQAAASAAASAIAFNQGEVCTAGSRLLVERSIKDRFL 321
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI--GTA 364
+E A + GNP D +T G +D MN VL IE G +GA L+AGG+RI T
Sbjct: 322 PMVIEALSAWKPGNPLDPATTVGALVDTQQMNTVLSYIEAGHSDGAKLVAGGKRILQETG 381
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G Y++PT+F VN+ M IA+EEIFGPV S+L FDT EE I AN+T YGLAA ++T N++
Sbjct: 382 GTYVEPTIFDGVNNAMKIAQEEIFGPVLSVLTFDTAEEAIQIANDTQYGLAAAVWTANIS 441
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A +K + AG+VWVN Y APFGGFK SG GR+ + A + Y E K+ I L
Sbjct: 442 KAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELKSTWIKL 499
>UniRef50_A0QGB6 Cluster: P-cumic aldehyde dehydrogenase; n=4;
Mycobacterium avium|Rep: P-cumic aldehyde dehydrogenase
- Mycobacterium avium (strain 104)
Length = 484
Score = 378 bits (930), Expect = e-103
Identities = 190/424 (44%), Positives = 265/424 (62%), Gaps = 10/424 (2%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R K+L++ DLI+ E A+L+S + GM +S + RY
Sbjct: 58 WSQLPGRERAKILWRIGDLIDEHAEEFAQLDSLNTGMPLLQAQLQMSTCSEFFRYYAGWC 117
Query: 124 DKIQGDT--IPTDG---DSF----SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGC 174
KI G + TDG D+F +YTLK+P V GLI PWN PI K+ ALAAGC
Sbjct: 118 SKINGTAYDVKTDGIATDTFVNMHAYTLKEPYSVVGLIFPWNGPIFNASAKLAPALAAGC 177
Query: 175 TVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSL 234
+++VKPAE+TPL+ EAG+P+GVVN++ G+G AG A+T HPDV K++FTGS
Sbjct: 178 SLLVKPAEETPLSALLLDRLVHEAGVPEGVVNLLTGYGHTAGAAITAHPDVEKVAFTGST 237
Query: 235 EVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASR 294
EVGK I +A+ NLK+VTLELGGKSP++I +DADL+ AI A G+F H GQ CV SR
Sbjct: 238 EVGKEIVRASA-GNLKKVTLELGGKSPVLIFDDADLDKAILMASLGIFVHSGQGCVCGSR 296
Query: 295 LYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANL 354
++VQ G+YD+ V+G A ++G P +E V+GP I + +N+V+G I+ GK +G +
Sbjct: 297 IFVQRGVYDRVVEGIAMMANTFKLGAPSEEGCVSGPLISQKQLNRVMGFIDEGKNDGVEV 356
Query: 355 LAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGL 414
+ GG R+ GY++ PTV +V+ M + ++EIFGPV +IL FD +E + AN+T YGL
Sbjct: 357 VTGGYRLDRKGYFVHPTVLTNVDPGMRLYQQEIFGPVVAILPFDDEDEAVAMANDTTYGL 416
Query: 415 AAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLE 474
AA +T NL A + K ++AG+V VN L H PFGG+K SG G E G + +E YL+
Sbjct: 417 AATAWTENLGRAHRIVKRLQAGSVQVNCQLVFDHDVPFGGYKQSGWGHEFGKEGLEIYLK 476
Query: 475 EKTV 478
K+V
Sbjct: 477 TKSV 480
>UniRef50_Q9RYT8 Cluster: Aldehyde dehydrogenase; n=29;
Bacteria|Rep: Aldehyde dehydrogenase - Deinococcus
radiodurans
Length = 524
Score = 378 bits (929), Expect = e-103
Identities = 192/473 (40%), Positives = 276/473 (58%), Gaps = 6/473 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI EWVDA G+TFD SP D + KVA+G FQ WR +
Sbjct: 34 FIGGEWVDAHSGKTFDAHSPVDNDFLVKVAEGDASDIDRAAKAAHDAFQT---WREVSGA 90
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ-GD 129
+R K+L+K ADLIE+ + +A LES D G + + ++ R+ A Q G
Sbjct: 91 ERRKILHKVADLIEKRAQEIAVLESVDTGQAIRFMKSAAARGAENFRFYADRAPGAQDGQ 150
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
++P G +Y+++QP+G G+I PWN P ++ K+ ALAAGCTVV KPAE +P++
Sbjct: 151 SLPAPG-FINYSIRQPIGPVGVITPWNTPFMLSTWKIAPALAAGCTVVHKPAEWSPVSAT 209
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAG+P GV N+V GFGE AG +LT HP V ++F G G I + G + L
Sbjct: 210 LLTEIMDEAGLPGGVHNLVHGFGESAGKSLTEHPLVKAVAFVGETTTGSHIMRQ-GADTL 268
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KRV ELGGK+P+++ +DADL+ A+ ++ G+ C ++SR+ +Q GIYD+F +
Sbjct: 269 KRVHFELGGKNPVVVFDDADLDKALDAVVFMIYSLNGERCTSSSRVLIQEGIYDEFTRRI 328
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
E A IRVG+P D T GP + KV+ E ++EGA + AGGER+G AG +++
Sbjct: 329 AERAANIRVGDPLDPDTEVGPLVHPRHFEKVMSYFECARQEGATIAAGGERVGEAGNFVR 388
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PT+F +DM IA+EEIFGPV + + F + ++ AN+ NYGLA ++T +L A +F
Sbjct: 389 PTLFTAARNDMKIAQEEIFGPVLTAIPFKDEADALELANDVNYGLAGYLWTNDLTRAHRF 448
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ +EAG +WVN+ PFGG K+SGIGR+ G + E Y+E K + ISL
Sbjct: 449 AHGLEAGMIWVNSENVRHLPTPFGGVKNSGIGRDGGDYSFEFYMETKNIAISL 501
>UniRef50_O33455 Cluster: P-cumic aldehyde dehydrogenase; n=7;
Proteobacteria|Rep: P-cumic aldehyde dehydrogenase -
Pseudomonas putida
Length = 494
Score = 376 bits (925), Expect = e-103
Identities = 201/472 (42%), Positives = 278/472 (58%), Gaps = 8/472 (1%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
I +W + GET +P +IA + +G+ F+ + WR
Sbjct: 20 IGGQWKGSISGETITVENPATEEIIAHIPQGRHEDIDEAVRVARATFE-SPAWRKIRPID 78
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNG--MVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
RG++L A IE + LA LES D G + + + + S I D RY+G K+ G
Sbjct: 79 RGRILENVARKIEEHADELAYLESLDTGKALTFAKAIDLPSTI-DVFRYMGGWCSKLGGT 137
Query: 130 TIPT--DGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T P DG + +YT ++P+GV G I PWN P+ + K+ +ALAAGCT+V+KP E TPL
Sbjct: 138 TPPISFDGREYHTYTRREPIGVVGAITPWNYPLALGSWKIASALAAGCTMVLKPTELTPL 197
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ EAG+P+G +NIV G G +AG AL HP V KI+FTGS VGK I + A
Sbjct: 198 STLRLAELCLEAGLPEGALNIVNGHGHEAGEALARHPGVDKITFTGSTVVGKKIVEYA-L 256
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N+KRVTLELGGKSP I+ DADL+ A VFF+ GQIC AASRL+VQ +YD+ V
Sbjct: 257 GNMKRVTLELGGKSPSIVFADADLDQVGLGAALAVFFNSGQICFAASRLFVQDSVYDQVV 316
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ A +VGN D T+ GP + +V+G +++G ++GA L+ GG+ +G GY
Sbjct: 317 EAVAAAAAQFKVGNGLDPDTLLGPLVSRKQQERVMGYVQSGIEQGARLVCGGKSVGEKGY 376
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
++QPTVFAD M IA+EEIFGPV S+++F E I AN+T YGLAA I+T ++ A
Sbjct: 377 FLQPTVFADAAPSMRIAQEEIFGPVVSVIRFKDEAEAIRMANDTAYGLAANIWTRDIKKA 436
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ + ++AG+VW+N + + APFGGFK SG GRE + + AY E KTV
Sbjct: 437 HRVAHRLQAGSVWINCHGVIDPAAPFGGFKQSGWGREVSEEGLSAYTETKTV 488
>UniRef50_Q11AE9 Cluster: Aldehyde dehydrogenase; n=10;
Bacteria|Rep: Aldehyde dehydrogenase - Mesorhizobium sp.
(strain BNC1)
Length = 505
Score = 375 bits (922), Expect = e-102
Identities = 200/475 (42%), Positives = 289/475 (60%), Gaps = 5/475 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ E A+DG+ FDT +P G V+ VA + F + EW A+
Sbjct: 22 FINGELCWAEDGDKFDTVNPATGEVLCSVAHCKKEDVDKAVIAARRSFN-DGEWSRAEPE 80
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQGD 129
R ++L + + LI + LA LES D+G +CL+ I + + + ++ G L DK G
Sbjct: 81 HRKEVLTRLSHLIRENAFELAVLESLDSGKTITDCLKEIGTEVANFFQWYGELIDKSFGK 140
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
PT + + +K+P GV G+I+PWN P+LM KV ALAAGC+ +VKPAEQTPL+
Sbjct: 141 VAPTGESALALIVKEPAGVVGIIVPWNFPLLMTAWKVAPALAAGCSCIVKPAEQTPLSAI 200
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
++AG+P GV+NI+PG GE AG A+ H DV ISFTGS EVG + +G +NL
Sbjct: 201 RMAELAQQAGLPDGVLNILPGLGETAGQAIGRHNDVDIISFTGSTEVGGFFLRYSGESNL 260
Query: 250 KRVTLELGGKSPLIIMNDADLN-LAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
K V LE+GGKSP I+++DADLN + +A S F++ GQ C A R V + + D+FV+
Sbjct: 261 KVVGLEMGGKSPFIVLDDADLNDDLVEHAVSSAFWNGGQNCSANMRQLVDTRVADEFVER 320
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYI 368
V A+ +VG+P D ST G + E M +V+G IE G+ EGA L GG R G GY+I
Sbjct: 321 VVARAEKYKVGDPLDPSTDIGAMVTEEHMKRVVGYIERGESEGARRLTGGARQG-RGYFI 379
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
+PTVF+ + +MTIA+EEIFGPV ++ L++ + A++T YGL A +FT +L+ AL
Sbjct: 380 EPTVFSGLRPEMTIAREEIFGPVLGVMPVKGLDDALRIASDTIYGLHATVFTRDLDRALH 439
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSG-IGRENGIKAVEAYLEEKTVIISL 482
++ + GTV VN + + PFGG+K SG + R+NG +A++ YL+ KT+ I+L
Sbjct: 440 LARRLPCGTVSVNGFSEGDIKTPFGGYKQSGSLSRDNGTEAMDQYLQTKTIWITL 494
>UniRef50_A5EL04 Cluster: Aldehyde dehydrogenase; n=10;
Bacteria|Rep: Aldehyde dehydrogenase - Bradyrhizobium
sp. (strain BTAi1 / ATCC BAA-1182)
Length = 492
Score = 375 bits (922), Expect = e-102
Identities = 197/479 (41%), Positives = 273/479 (56%), Gaps = 7/479 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI +W G+ F++F P A + + ++ EW S
Sbjct: 7 FIGGQWRQPASGDYFESFDPFLAQPWALIPRCDARDVDAAVAAARQALEQG-EWANMHPS 65
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
QRG+LL +F DLI RD ++LA++E DNG +Y + IP Y G LADK++G
Sbjct: 66 QRGQLLRRFGDLIARDADHLARIEVQDNGKLYAEMRGQVGYIPQWFHYFGGLADKVEGAV 125
Query: 131 IPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+P D D F+YT +PVGV I PWN P+L+ K+ ALAAGCT+V+KP+E T +
Sbjct: 126 VPIDKPDMFTYTRHEPVGVVAAITPWNSPLLLATWKLAPALAAGCTIVIKPSEFTSASTI 185
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+EAG P GV+N+V GFG D G LT H V KI+FTG G+ + + A
Sbjct: 186 ELMRLVEEAGFPPGVLNVVTGFGADVGEPLTSHKGVDKIAFTGGENSGRHVLRNAA-QTF 244
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KR TLELGGKS ++ DADL+ A+ SG+F GQ C+A SRL V I+D F+
Sbjct: 245 KRTTLELGGKSAQLVFPDADLDNAVKGVVSGIFAATGQTCIAGSRLLVHESIHDAFLDKF 304
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----G 365
V A+ R+G+P + T GP + +VL I ++EGA + GG+ G
Sbjct: 305 VALARTARMGDPMNMDTQVGPVTTQPQYRRVLSCIAMAREEGAECVMGGKPADRPECGQG 364
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
++++PTVFA VN+ M IA+EE+FGPV S++KF +E AN+T YGLAAG++T +
Sbjct: 365 WFVEPTVFAGVNNAMRIAQEEVFGPVLSVIKFREDDEAYAVANDTAYGLAAGVWTNDQRR 424
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPK 484
A ++ + AGTVW N Y +++ APFGGFK SGIGRE+G A+ YLE K V +S K
Sbjct: 425 AFTAARRLRAGTVWTNTYRAVSYMAPFGGFKASGIGRESGQDAIMEYLETKCVWMSYGK 483
>UniRef50_A0R5S7 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Mycobacterium smegmatis (strain
ATCC 700084 / mc(2)155)
Length = 511
Score = 373 bits (917), Expect = e-102
Identities = 190/481 (39%), Positives = 270/481 (56%), Gaps = 7/481 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+FI E V A DG TFD++ P G V A++ + F+ W
Sbjct: 28 MFIAGEAVSAADGATFDSYEPRSGRVWARLPRANSTDIDRAVRAARAAFE--GPWGAVSP 85
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+ RG+ L K A +++R + L +ES DNG + + + Y + G+
Sbjct: 86 ADRGRFLMKIAAVVDRHRDQLTVIESRDNGKPVREVRAEIDAVVRYFEYFAGVCQTTVGE 145
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
T P +FSYT ++PVGV G I+PWN P+LM K+ ALA G T+++KPAE+T ++
Sbjct: 146 THPQAATAFSYTRREPVGVVGAIVPWNSPLLMLAWKLSPALAGGNTIILKPAEETSVSAV 205
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
E G+P GV N+V G GE+AG AL HPDV KI+FTGS EVGK I A ++L
Sbjct: 206 VFAQLIAEVGLPDGVFNVVTGIGEEAGAALVAHPDVDKIAFTGSTEVGKQI-AATAASDL 264
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K VT ELGGKSP +I +DADL+ A+ G+F GQ C AASR++VQ I+D+F+
Sbjct: 265 KLVTFELGGKSPTVIFDDADLDAAVHRTAYGIFSAAGQTCQAASRIFVQDTIHDEFLDRF 324
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----G 365
A+ IRVG+P E T G QI ++ G + +G +EGANL+ GG + A G
Sbjct: 325 AALARRIRVGDPLSERTQMGAQISAQHRERIAGYVASGIQEGANLVCGGTQPTEAPLAQG 384
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
YY PT+ VN DM + +EEIFGPV ++ F + + +AN+T YGLA ++T +++
Sbjct: 385 YYYSPTILDGVNRDMRMIREEIFGPVTGVMSFTDEADAVAKANDTEYGLAGSVWTRDVSR 444
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
A + + + AG +WVN T+ H PFGG+K SG GRE G +E Y K+V + +
Sbjct: 445 AHRVAASIAAGLIWVNTTRTINHLVPFGGYKQSGYGREGGQAVMEHYTRIKSVWVDMQDD 504
Query: 486 L 486
L
Sbjct: 505 L 505
>UniRef50_P54114 Cluster: Aldehyde dehydrogenase [NAD(P)+] 2; n=8;
Saccharomycetales|Rep: Aldehyde dehydrogenase [NAD(P)+]
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 506
Score = 373 bits (917), Expect = e-102
Identities = 202/482 (41%), Positives = 281/482 (58%), Gaps = 11/482 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI+NE+ + DG+T +T +P G I F ++ W +
Sbjct: 23 LFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAF--DNVWSKTSS 80
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVY-KNCLRILSGIPDSVRYLGSLADKIQ- 127
QRG L LIE + + LA LE+ D G + N + L+ I + RY DK
Sbjct: 81 EQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNM 140
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G+TIP + F+YTLK P GV I+PWN P+ M K+ ALAAG TV++KPAE T L+
Sbjct: 141 GETIPLTFNKFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLS 200
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
K+AG P GVVN++PG+G G AL H D+ KISFTGS +VG + +A+G +
Sbjct: 201 LLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQS 260
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NLK +TLE GGKSP ++ DADL+ AI + +G+FF+ GQIC A SR+YVQS IYDKFV+
Sbjct: 261 NLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVE 320
Query: 308 GAVEYAK----AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKK-EGANLLAGGE-RI 361
E AK +PFDE + GP I + +++ IE GKK E ++ E I
Sbjct: 321 KFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPI 380
Query: 362 GTA-GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G A GY+I PT+F DV + + ++EIFGPV + KF ++ + AN+T YGLA+ +FT
Sbjct: 381 GGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFT 440
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++ A F++ ++AGTVW+N + PFGGFK SGIGRE+G V+ YL+ K+V +
Sbjct: 441 KDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHV 500
Query: 481 SL 482
L
Sbjct: 501 DL 502
>UniRef50_Q39MG6 Cluster: Aldehyde dehydrogenase; n=1; Burkholderia
sp. 383|Rep: Aldehyde dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 496
Score = 372 bits (916), Expect = e-102
Identities = 191/474 (40%), Positives = 275/474 (58%), Gaps = 2/474 (0%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L I WVDA G TF+T +P V+ +VA+ F S W
Sbjct: 25 RLLIGGRWVDAASGNTFETINPATEQVLCRVAEADSADVDAAVIAARRAFDAPS-WGGLS 83
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
R + L K AD IE+ + LA +ES DNGM L ++ D VRY K+ G
Sbjct: 84 PHARTRALLKIADAIEQHVDELAAIESLDNGMPLWFALAAVTATIDIVRYYAGWCSKVLG 143
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
TIP+DG + YTL++P+GVCG I+PWNVPILM K AL G TV++KPAE LT
Sbjct: 144 TTIPSDGSTLIYTLREPLGVCGQIIPWNVPILMAAIKFANALCCGNTVILKPAELACLTS 203
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+E +P GV+N++PG+G AG AL HP V KI+FTGS VGK I + A T N
Sbjct: 204 IRLAELIQETDLPPGVINVLPGYGPTAGAALAQHPGVDKIAFTGSTPVGKQITRDA-TLN 262
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LK+VTLELGGK+P +I DAD+ A+ A + GQ+C A +RL+VQ GI+++ +
Sbjct: 263 LKKVTLELGGKAPNVIFADADIEKAVQAAVKTFCGNSGQVCSAGTRLFVQEGIHEQVAER 322
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYI 368
+ A + G+PF T GP I ++V I G++ GA L GG+ AGY++
Sbjct: 323 VAQIAATWKAGDPFASDTKLGPLISAKQRDRVWSYIGVGQEGGATLRLGGDPWRGAGYFV 382
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
+PTVF +V + M IA+EEIFGPV SI+ F + + +AN+T YGL+A ++T ++ A +
Sbjct: 383 EPTVFDNVRNGMRIAQEEIFGPVLSIIPFKDEGDAVLQANDTTYGLSAAVWTRDVARAHK 442
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ ++AG +W+N + FGG+K SG GRE G ++++AY + K++++ +
Sbjct: 443 VVRALKAGRLWINTFGESDPAMAFGGYKQSGWGREFGQESIDAYTQTKSIMLRM 496
>UniRef50_P71016 Cluster: Betaine aldehyde dehydrogenase; n=16;
cellular organisms|Rep: Betaine aldehyde dehydrogenase -
Bacillus subtilis
Length = 490
Score = 370 bits (910), Expect = e-101
Identities = 196/474 (41%), Positives = 278/474 (58%), Gaps = 7/474 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFID EW+ A+ + +P + IA V++G F + EW
Sbjct: 5 LFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIKAIAAARRAFDKG-EWSSLSG 63
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+RGK++ K A+LI RD E LA+LES D G + + I + +Y LADK G+
Sbjct: 64 LERGKIVLKIAELIRRDLEELAELESLDTGKTLEESKADMDDIANVFQYYAGLADKDGGE 123
Query: 130 TIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
I + DS S +++P+GVCG I PWN P+L K+ ALAAG T+V+KP+E TPLT
Sbjct: 124 IISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVMKPSEITPLTT 183
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+EAG+PKGV N+V G G G L + DV ISFTG +E GK I +AA + N
Sbjct: 184 IKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAA-SGN 242
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+K++ LELGGK+P I+ DADL +A+ A + VFFH GQ+C A SRL V+ I+D+F+
Sbjct: 243 VKKIALELGGKNPNIVFKDADLEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFLAE 302
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---- 364
V+ AK I++GN F T +GP I KV +E G +EGA L GG+R
Sbjct: 303 LVKRAKRIKLGNGFHAETESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPEDPELQN 362
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G++ +PT+F++ N DM I +EE+FGPV ++ F + EEVI+ AN+T YGLA +++ ++
Sbjct: 363 GFFYEPTIFSNCNSDMRIVQEEVFGPVLTVETFSSEEEVIELANDTIYGLAGAVWSKDIE 422
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ + + GTVW+N++ QAP+GG+K SG GRE G +E Y E K V
Sbjct: 423 KCERVAARLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEVKHV 476
>UniRef50_Q5L3J6 Cluster: Aldehyde dehydrogenase; n=6; Bacteria|Rep:
Aldehyde dehydrogenase - Geobacillus kaustophilus
Length = 513
Score = 369 bits (909), Expect = e-101
Identities = 191/494 (38%), Positives = 292/494 (59%), Gaps = 16/494 (3%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
++ + LFID +W A GETF ++P G V+A VAK F ++
Sbjct: 6 QVHHFPLFIDGQWQPATSGETFHVYNPATGEVVATVAKATADDVDRAVKAARKAFDE-TD 64
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W+ +R ++L A I + + LA LE+ +G + I I +V ++A
Sbjct: 65 WKAMKPKERARVLNAIAQAIAANAQELAYLEAISSGGTIRRISSI--DILQTVDLFQTMA 122
Query: 124 DKIQ----GDTIPTD---GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTV 176
+ +Q +T+P G + ++ ++P+GVC I PWN+P+++ K+ ALAAG T+
Sbjct: 123 NIVQEYPFSETLPIPPFPGPAHNFVWREPIGVCAAITPWNLPLMIASWKIAPALAAGNTI 182
Query: 177 VVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEV 236
VVKPA TPL+ +P GV+N+V G G D G AL HP V K++FTGS EV
Sbjct: 183 VVKPASYTPLSTLKLAEIISSF-VPPGVINVVAGPGADVGEALVRHPQVDKVAFTGSTEV 241
Query: 237 GKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
G+ I A +K VTLELGGKSP I++ DADL+LA+P + GVF H GQ+C + +RL+
Sbjct: 242 GRRIM-ALAAETVKNVTLELGGKSPNILLEDADLDLAVPGSLFGVFLHSGQLCESGTRLF 300
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
V ++D+ V+ V K +++G+P D +T GP I + VL IE GK+EGA ++
Sbjct: 301 VPDRLHDEVVERLVALTKTLQIGHPLDPATDVGPVISKRQKETVLSYIEAGKQEGATIVC 360
Query: 357 GGERIGT----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNY 412
GG + G+++ PT+F++V +DM IA+EEIFGPV SI+++ +EE + AN+T Y
Sbjct: 361 GGHEVEVPGCEGGHFVAPTIFSNVTNDMKIAQEEIFGPVLSIIRYHDVEEAVTMANDTIY 420
Query: 413 GLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAY 472
GLAAG++T ++N A + ++AG VW+N++ + + APFGG+K SGIGRE G +++AY
Sbjct: 421 GLAAGVWTRDVNKAYAIAGRLQAGVVWINDWHMLRNDAPFGGYKQSGIGREMGKYSLDAY 480
Query: 473 LEEKTVIISLPKKL 486
+ K V S+ +L
Sbjct: 481 TQLKHVHTSMVPEL 494
>UniRef50_Q391L7 Cluster: Betaine-aldehyde dehydrogenase; n=12;
Proteobacteria|Rep: Betaine-aldehyde dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 488
Score = 369 bits (909), Expect = e-101
Identities = 193/480 (40%), Positives = 279/480 (58%), Gaps = 9/480 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T+LFID +VDA D T D +PHDGSVI K+A F + W
Sbjct: 3 TQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVEAATRAFPK---WSAL 59
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKI 126
A++RG+LL + AD IE + E LA+LES D G ++ + + RY G +ADK+
Sbjct: 60 PAAERGRLLLRLADAIEANAEELAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKL 119
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
QG IP + +Y + P+GV G I+PWN P++ K+ ALAAG TVV+KP+E TPL
Sbjct: 120 QGSVIPVETGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPL 179
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ E G P GVVNIVPG+G AG L HP V KI+FTGS G+ I +A+
Sbjct: 180 STLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVEAS-Q 238
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
NLKRV LELGGK I+ +DADL+ AI A +F +QGQ C+A SRL + I D F+
Sbjct: 239 GNLKRVQLELGGKGANIVFDDADLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFL 298
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----ERIG 362
+ V A +IR+GNP D +T GP + +++VL ++ +++G +L GG +
Sbjct: 299 ERFVALASSIRIGNPLDANTEMGPLTSKQHLDRVLSFVDVAREQGGRVLTGGSAPQDPAL 358
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GYY++PTV + +A+EE+FGP ++L+F + +E + AN T YGL +G++T +
Sbjct: 359 ANGYYVRPTVIEAKSAADRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTKD 418
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ A + + + AG W+N Y + +PFGG SG GRE G +A+ Y E ++V +++
Sbjct: 419 LSRAHKMASQINAGMCWINCYKRVNPGSPFGGVGQSGYGREMGFEAMHDYTEARSVWVNV 478
>UniRef50_Q11FB7 Cluster: Aldehyde dehydrogenase; n=5;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 509
Score = 368 bits (905), Expect = e-100
Identities = 185/477 (38%), Positives = 273/477 (57%), Gaps = 7/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI + G +F P G V + A+ F N WR
Sbjct: 20 ELFIGGRFRAPSSGRFIPSFDPTTGEVWYEFAEADAADVDAAVTSATKAFH-NPAWRRMT 78
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+ RGKL+ + A+L+ + LA +E+ DNG + K + + +PDS Y +ADK+QG
Sbjct: 79 QTDRGKLIRRLAELVLEHADELALMETRDNGKLIKEMMAQMRAMPDSYIYFAGMADKLQG 138
Query: 129 DTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
DTIP + DS +Y+ ++P+GV G+I PWN P+++ + LA G TVVVKP+E +
Sbjct: 139 DTIPVNKLDSLNYSQREPLGVVGMITPWNSPLMLLTGTLAPCLAIGNTVVVKPSEHATAS 198
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAGIP+GVVN+V G G G ALT HP +AKI FTGS G+ I A
Sbjct: 199 TLALAELVVEAGIPEGVVNVVTGTGAVTGEALTRHPGLAKIVFTGSTATGRRIA-ANAAE 257
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NL +ELGGKSP ++ +D D+ A+ SG+F GQ CVA SR +V++ IYD+F++
Sbjct: 258 NLIPCQMELGGKSPHVVFSDVDIERAVNGVVSGIFAAAGQTCVAGSRCFVEANIYDRFLE 317
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--- 364
VE + IRVG+P +EST GP +S + K+ G + +G ++GA + GG R
Sbjct: 318 ALVERTRHIRVGHPMEESTDVGPLAMKSQLEKIEGYVASGARDGAKIAVGGRRPKDGDLA 377
Query: 365 -GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G+Y +PTV AD +DM ++E+F PV ++ F E+I AN+T YGLA+GI+T ++
Sbjct: 378 RGWYFEPTVMADARNDMKFMRDELFAPVVGVMPFRDEAEMITLANDTEYGLASGIWTRDI 437
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ A++F+ ++AGTVW+N Y + A+ + GGFK+SG GR G + + K V+I
Sbjct: 438 DRAMRFASQIDAGTVWINTYRSAAYMSANGGFKNSGYGRRGGFDVMREFSRSKNVLI 494
>UniRef50_A7Q2D6 Cluster: Chromosome chr1 scaffold_46, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_46, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 538
Score = 365 bits (897), Expect = 2e-99
Identities = 185/360 (51%), Positives = 236/360 (65%), Gaps = 3/360 (0%)
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKI G TIP DG TL +P+GV G I+PWN P+LM+ KV ALA G TV++K AE
Sbjct: 176 ADKIHGLTIPADGLHHVQTLHEPIGVAGQIIPWNFPLLMYAWKVGPALACGNTVILKTAE 235
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPL+ EAG+P GV+N+V G+G AG AL H DV K++FTGS E GK++ +
Sbjct: 236 QTPLSALHLFH---EAGLPPGVLNVVSGYGPTAGAALASHMDVNKLAFTGSTETGKIVIQ 292
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A +NLK VTLELGGKSP I+ DA+++ A+ A +FF+QGQ C A S YV IY
Sbjct: 293 LAEKSNLKPVTLELGGKSPFIVCEDANVDEAVELAHFSLFFNQGQCCCAGSHTYVHERIY 352
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ A A VG+PF T GPQID K+L I +G GA L GGER G
Sbjct: 353 DEFVEKAKARALKRVVGDPFKAGTEQGPQIDSEKFEKILRYIRSGVDNGATLETGGERFG 412
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
T GY+I+PTVF++V DDM A++EIFGPVQSILKF L+EVI RAN +N GLAAG+FT N
Sbjct: 413 TGGYFIKPTVFSNVQDDMLKAQDEIFGPVQSILKFKDLDEVIRRANASNCGLAAGVFTQN 472
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A ++ + GTVW+N + PFGG+K SG GRE GI ++ YL+ K V+ L
Sbjct: 473 IDTANTLTRALRVGTVWINCFDVFDAAIPFGGYKMSGNGREKGIYCLQNYLQVKAVVSPL 532
Score = 144 bits (349), Expect = 5e-33
Identities = 70/152 (46%), Positives = 95/152 (62%)
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
FG AG AL H DV K++FTGS + G+ I ++A +NLK VTLELGGKSP I+ DA++
Sbjct: 6 FGPTAGAALASHMDVDKVAFTGSTKTGEAILQSAAMSNLKPVTLELGGKSPFIVCEDANV 65
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
+ A+ A +FF+QGQ C + SR +V +YD+FV+ A A VG+PF GP
Sbjct: 66 DEAVEMAHFALFFNQGQCCASGSRTFVHESVYDEFVEKAKARALRRTVGDPFKAGIEQGP 125
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
QID K++ I +G + GA L +GGER G
Sbjct: 126 QIDSKQFEKIMRYIRSGVESGATLESGGERFG 157
>UniRef50_Q6W1I3 Cluster: Aldehyde dehydrogenase; n=4;
Proteobacteria|Rep: Aldehyde dehydrogenase - Rhizobium
sp. (strain NGR234)
Length = 502
Score = 363 bits (894), Expect = 4e-99
Identities = 186/481 (38%), Positives = 271/481 (56%), Gaps = 5/481 (1%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
K K+FID W D+ +G TFD F P G +I + G F + WR
Sbjct: 24 KPQKMFIDGAWSDSSNGATFDIFEPSTGGLITRAPSGTPEDLDRAVRAARRQFDGGA-WR 82
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLAD 124
+R +LL+ ADLIE + LA++E+ D G I + G D+ RY A
Sbjct: 83 RLKPLERERLLHSLADLIEAHSDELAEIEAIDMGKSVTFAREIDIRGTVDTFRYFAGWAS 142
Query: 125 KIQGDTIPTD--GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
K+ G T+ G+ +YT K+P+GV I+PWN P+ K+ ALA GCT +VKPAE
Sbjct: 143 KLHGRTVEPSLPGNYLAYTRKEPLGVVAAIVPWNFPLQTLAWKLAAALAVGCTAIVKPAE 202
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
T L+ +EAGIP GVVNIV G G G A++ HP + K++FTGS VG+ + +
Sbjct: 203 LTSLSTLRFAELVQEAGIPDGVVNIVTGKGSIIGAAMSTHPGINKVTFTGSTPVGQEVGR 262
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A NLK VTLELGGKSP+++++DADL A +GVFF+ GQ+C A +R+YVQ ++
Sbjct: 263 TA-VGNLKHVTLELGGKSPVLVLDDADLQSAAVAVANGVFFNSGQVCDAGTRVYVQGSVH 321
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D F+ V A+++ D GP + V G IE G++EGA L+ GG +
Sbjct: 322 DAFLDELVSVTSALKIAPGLDRDCYIGPLVSAQQKKVVSGYIEAGRREGAELIHGGASLH 381
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G++I+P +F+ M+I +EEIFGPV FD L++ + AN+T +GLAA I++ +
Sbjct: 382 RQGHFIEPAIFSHCKPQMSIVREEIFGPVLVTSPFDDLDDAVSLANDTPFGLAAAIYSND 441
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ + AG+++VN + T+ PFGGFK SG G++ G + ++ +E K V I+L
Sbjct: 442 LSRVHTLIPRLHAGSIYVNAHSTIDPAMPFGGFKASGFGKDLGPEQLDYLMETKAVWITL 501
Query: 483 P 483
P
Sbjct: 502 P 502
>UniRef50_UPI00006CDA6E Cluster: aldehyde dehydrogenase; n=2;
Tetrahymena thermophila SB210|Rep: aldehyde
dehydrogenase - Tetrahymena thermophila SB210
Length = 492
Score = 362 bits (890), Expect = 1e-98
Identities = 192/482 (39%), Positives = 279/482 (57%), Gaps = 6/482 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
TKLFI+ ++VD +T +P +I ++A+ F W
Sbjct: 13 TKLFINGKFVDGALKKTIPVINPATEELICEIAEATEQDVELAIDAAEASFPI---WSKL 69
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
R + L K A L+E + E LES DNG + ++ + +RY ADKI
Sbjct: 70 PQRDRTEYLLKLASLLEANKEEFIALESLDNGKPLEGATFDINDVIGHLRYYAGWADKIT 129
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G + + YT ++P GV GLI PWN P++M K ALAAG +V+KP+E TPLT
Sbjct: 130 GKSFSSLDQQIFYTRREPYGVVGLISPWNFPLMMAEWKYAPALAAGNCIVLKPSEVTPLT 189
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAG P GV N+VPG+G AGVA+TH ++KISFTGS VG+ I +A+
Sbjct: 190 VLRLCELVNEAGFPPGVFNVVPGYGHVAGVAITHSKRISKISFTGSSFVGRKILEASSQT 249
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NLK+V LELGGKSP+++ DADL+ A A G F+ GQ C A +RL+V +YDK ++
Sbjct: 250 NLKKVVLELGGKSPVVVFPDADLDKAAEVAWYGCMFNMGQSCDAGTRLFVHEDVYDKLLQ 309
Query: 308 GAVEYAKAIRVGNPFD-ESTVNGPQIDESMMNKVLGLIETGKK-EGANLLAGGERIGTAG 365
EY + + +G+ F+ +++ +GP + + ++V+ I K+ E GGER G G
Sbjct: 310 KLKEYEQNVVIGDSFEVQNSNHGPLVSKLQFDRVMSYITHAKEVEKLQCFMGGERWGNKG 369
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILK-FDTLEEVIDRANNTNYGLAAGIFTTNLN 424
Y+I+PT+F +V+D+ +A+EEIFGPV +LK + T +EVI RAN+TNYGLAA T N
Sbjct: 370 YFIKPTIFINVDDNSKLAREEIFGPVLVVLKPWKTFDEVIKRANDTNYGLAAYAVTQNAG 429
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPK 484
N +F + V+AG+ ++N AHQ PFGG+K+SG G++NG + + Y + K+V SLP
Sbjct: 430 NVEKFVREVKAGSFYINQGALSAHQMPFGGYKESGFGKDNGEEGLLEYTQLKSVYYSLPN 489
Query: 485 KL 486
+
Sbjct: 490 PM 491
>UniRef50_Q5LLB4 Cluster: Phenylacetaldehyde dehydrogenase; n=58;
Bacteria|Rep: Phenylacetaldehyde dehydrogenase -
Silicibacter pomeroyi
Length = 504
Score = 361 bits (887), Expect = 3e-98
Identities = 197/481 (40%), Positives = 273/481 (56%), Gaps = 10/481 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KL + A DG T D F+P G +A+V G + +W
Sbjct: 26 KLLLGGTSTAASDGRTMDVFNPATGKKLAEVPWGGAAEIDLAVKAAQAALE--GDWSRMR 83
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADKIQ 127
+R ++L ADLIE + E LA+LE+ +NG V + L + + +RY+ + KI+
Sbjct: 84 PVERQRVLLNLADLIEANGEELAQLETLNNGKSVMLSRLVEVGNSSNYLRYMAGWSTKIE 143
Query: 128 GDTI------PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
G TI P +YT K+PVGV G I PWN P+ M + K+ ALA G TVV+KPA
Sbjct: 144 GSTIDVSIAVPPGAKYQAYTRKEPVGVVGAITPWNFPLNMAIWKLAPALACGNTVVLKPA 203
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E+TPLT EAG+P GVVN+V G G +AG ALT HP V K++FTGS EVGK+I
Sbjct: 204 EETPLTSLRLGELCLEAGLPPGVVNVVSGTGAEAGAALTAHPGVNKLTFTGSTEVGKIIG 263
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
A ++KRVTLELGGK+P+++ +D DL+ A G+ F+ GQ C A +R+Y Q GI
Sbjct: 264 IQA-MRDMKRVTLELGGKAPMVMFDDMDLDQLSEAARIGILFNSGQTCCAGTRIYAQRGI 322
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+ + A+ VG+ D + P + V I G +EGA L
Sbjct: 323 YDRICETMANVVGALSVGSGLDPANAINPMVSAKHQAHVSACIAGGVEEGATPLLDTGAY 382
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+++P +F DV DM I ++E+FGPV +I FD +E I AN+T YGL A I+TT
Sbjct: 383 DGEGYFVRPQIFTDVRQDMRIMQDEVFGPVFTITPFDDPDEAIRMANDTRYGLGASIWTT 442
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
NLN ++ ++AGTVWVN++ PFGG+K SGIGRE+G A++AYLE K+V I+
Sbjct: 443 NLNTMHRYVPQLQAGTVWVNSHNVPDANMPFGGYKQSGIGREHGRAALDAYLETKSVCIA 502
Query: 482 L 482
+
Sbjct: 503 V 503
>UniRef50_Q01RS0 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1;
Solibacter usitatus Ellin6076|Rep: Aldehyde
dehydrogenase (NAD(+)) - Solibacter usitatus (strain
Ellin6076)
Length = 469
Score = 360 bits (885), Expect = 5e-98
Identities = 185/461 (40%), Positives = 273/461 (59%), Gaps = 6/461 (1%)
Query: 29 SPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIERDFE 88
SP G ++ KV F+ N WR D S+R ++L+ +L+ + +
Sbjct: 10 SPATGELLGKVPDFDAEAVDCAVAAARASFE-NKTWRGLDPSKRERILWNIGELLLKYRD 68
Query: 89 YLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVG 147
L++L S + G + ++ D Y K G+TIP DG +YTL++PVG
Sbjct: 69 ELSRLISQETGKTLREAAGADVAPAADCFHYYAGWVRKQYGETIPVDGPYLNYTLREPVG 128
Query: 148 VCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNI 207
V G I+PWN P+ KV ALA GC+VV+KP+E TPL+ EAG+P GV+ +
Sbjct: 129 VVGAIVPWNFPLQTAAWKVAPALACGCSVVLKPSELTPLSALRFGEICAEAGLPAGVLVV 188
Query: 208 VPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMND 267
G+GE G AL H DV KISFTGS+ + + + + +NLKR++LELGGKSP I+ D
Sbjct: 189 ATGYGETTGEALALHEDVDKISFTGSVTTARKLLQNSAVSNLKRLSLELGGKSPNIVFPD 248
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTV 327
AD + A+ A G++ ++G++C A SRL + I+D+FV+ A+ +R+GNP D +T
Sbjct: 249 ADFDAAVRAALWGIYGNKGEMCTAGSRLLLHEEIHDRFVEELASKARKLRLGNPLDPATQ 308
Query: 328 NGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----GYYIQPTVFADVNDDMTIA 383
GPQI ++++L IE GK EGA L+ GGER G++++PT+FA V+ DM IA
Sbjct: 309 MGPQISGRQLDRILDYIEAGKTEGARLVCGGERDTEGDKAHGFFVKPTIFAGVHPDMRIA 368
Query: 384 KEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNY 443
+EEIFGPV S+++F EE + AN T YGLA+ ++T +L A + + ++AG+VWVN Y
Sbjct: 369 REEIFGPVLSVMRFRDAEEAVRIANATTYGLASAVWTNDLKLAHRMAAALKAGSVWVNTY 428
Query: 444 LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPK 484
+PFGG+K SG GR+ G A++ Y K+V I+L K
Sbjct: 429 NAFDSGSPFGGYKQSGFGRDLGSYALDQYTNVKSVWIALGK 469
>UniRef50_Q98H34 Cluster: NADP-dependent aldehyde dehydrogenase;
n=14; Proteobacteria|Rep: NADP-dependent aldehyde
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 524
Score = 359 bits (883), Expect = 9e-98
Identities = 184/475 (38%), Positives = 271/475 (57%), Gaps = 4/475 (0%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
K +L ID + VDA+DG T SP G +++ A+ F+ W
Sbjct: 39 KNYRLLIDGKHVDARDGRTIARKSPGHGFTVSRYAQAGEAEVEAAVQAAHKAFE-TGPWP 97
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
A +R +L++ ADLIE E +A+L++ ++G + G D RY SLA
Sbjct: 98 RMKAGERAAILFRAADLIEARLEDIARLDALESGKPIAQARGEIGGAVDIWRYGASLART 157
Query: 126 IQGDTIPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
+ G++ GD+ L++P+GV +I PWN P L+ K+ ALAAGCT VVKP+E T
Sbjct: 158 LHGESYANLGDAMLGVVLREPIGVVSIITPWNFPFLIVSQKLPFALAAGCTAVVKPSEMT 217
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
+ EAG+P GVVNI+ G G D G + HP V +SFTGS VGK+ A+
Sbjct: 218 SASTFVLGDILLEAGLPAGVVNILAGLGADVGAPMVSHPLVEMVSFTGSTRVGKMTM-AS 276
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+LK+V++ELGGK+ I+ DADL A A G FF+ G+ C A SRL V I D
Sbjct: 277 AAQSLKKVSMELGGKNGQIVFPDADLEAAADAAVFGGFFNAGECCNAGSRLIVHEAIADD 336
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT- 363
F+ + VG+P D+ T G I + KV + EG+N+ +GG+++ +
Sbjct: 337 FLSAVKALTARVTVGDPLDDQTKVGAMISSDHLAKVTDYVTAAAGEGSNVYSGGKQLASN 396
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
AG Y+ PT+ V +DM IA+EE+FGPV S+L F+++E+ + ANNT YGL+AG+++ ++
Sbjct: 397 AGQYLDPTIIRGVTEDMAIAREEVFGPVLSVLTFESIEKALHIANNTPYGLSAGVWSASI 456
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ + ++ V +GTVWVN ++ + PFGG+K SG+GRE G +AVE Y EEKT+
Sbjct: 457 DTCMSVARGVRSGTVWVNTFMEGYPELPFGGYKQSGLGRELGKRAVEDYTEEKTI 511
>UniRef50_A1SEY4 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1;
Nocardioides sp. JS614|Rep: Aldehyde dehydrogenase
(NAD(+)) - Nocardioides sp. (strain BAA-499 / JS614)
Length = 493
Score = 357 bits (878), Expect = 4e-97
Identities = 183/479 (38%), Positives = 277/479 (57%), Gaps = 8/479 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LF+D W ++ G T + SP DG ++ + A+G F W DA
Sbjct: 15 LFVDGRWQPSRTGRTSERTSPGDGRLVGRYARGDGADVDLAVAAARRAFDEGP-WPTIDA 73
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
++R ++ + ADL+ + + + + + G + + Y +LA +G+
Sbjct: 74 TKRAAIMRRAADLLRERADTIGRRIALELGKPISMARNEVVLTAEVFDYYAALALDQRGE 133
Query: 130 TIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
I + +K+PVGV G+I PWN P+L+ KV ALAAGCT+V KPA TP +
Sbjct: 134 LISQHTASALGMIVKEPVGVVGMITPWNFPLLLLSWKVAPALAAGCTMVAKPASLTPGST 193
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+AG+P GV N+V G G + G AL HP + KI+FTGS EVG+ + +AA
Sbjct: 194 LDLASVLADAGVPDGVYNVVTGGGAEVGDALAQHPGIDKIAFTGSTEVGQTVMRAA-VGT 252
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+K+V++ELGGKSP I+ DADL A+ A G+F + GQ C A SRL VQ ++++FV
Sbjct: 253 VKKVSMELGGKSPNIVFADADLKQAVRGAYWGIFLNSGQACQAGSRLLVQREVHEEFVSS 312
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG---TAG 365
VE A++ +VG+P DE T GP +D++ ++ VL I G++ GA L+AGG R+G G
Sbjct: 313 LVEMARSSKVGDPLDEGTQIGPMVDQAQLDTVLDYIGKGREAGAALVAGGNRLGGELADG 372
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y++PT+F + D I++EEIFGPV ++ FDTL+E + AN++ YGLA+ +++TN++
Sbjct: 373 LYVEPTIFDNAAPDHAISREEIFGPVLAVTPFDTLDEAVRLANDSPYGLASAVWSTNIDT 432
Query: 426 ALQFSKHVEAGTVWVNNY--LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A++ SK + AGTVW+N Y + P GG+K SGIGRE G + + Y E K + + L
Sbjct: 433 AIKTSKRLRAGTVWINAYHDAGLPFCMPMGGYKSSGIGRELGREGLAQYFETKAIHLRL 491
>UniRef50_Q88K06 Cluster: Aldehyde dehydrogenase family protein;
n=18; Bacteria|Rep: Aldehyde dehydrogenase family
protein - Pseudomonas putida (strain KT2440)
Length = 503
Score = 356 bits (876), Expect = 6e-97
Identities = 182/478 (38%), Positives = 273/478 (57%), Gaps = 10/478 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFIDN+WV A+ GET D +P +G ++ + F WR
Sbjct: 23 LFIDNQWVTAEYGETLDIINPANGKILTNIPNATAADVDRAVQAAQRAFVT---WRTTSP 79
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQG 128
++R L K ADL+E D + A LE+ D G + + + D RY +
Sbjct: 80 AERANALLKIADLLEADADRFAVLETLDVGKPIRESRSVDIPLAIDHFRYFAGVIRSQSD 139
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
+ + D + S L +P+GV G ++PWN P+LM K+ A+AAG TVV+KP+E TP+T
Sbjct: 140 EAVMLDEQTLSIALSEPLGVVGQVIPWNFPLLMAAWKIAPAIAAGNTVVIKPSELTPVTI 199
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+ +P GVVNIV G G G AL HPD+ K++FTGS VG+L+ AA
Sbjct: 200 LELAKIFAKV-LPAGVVNIVTGLGTTVGQALLDHPDLRKLAFTGSTRVGELVANAAAKKI 258
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+ TLELGGKS I+ DA+ + A+ A + ++QGQ+C + +RL+V IY++F+
Sbjct: 259 IP-ATLELGGKSANIVFPDANWDKAVEGAVLAILWNQGQVCESGARLFVHESIYERFLAE 317
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG----TA 364
+A+RVG+P + T+ G Q+ ++ M ++LG ++ K+EGA +L GG R+ A
Sbjct: 318 LKHKFEAVRVGDPLNPDTMMGAQVSKTQMERILGYVDIAKEEGAEVLIGGGRLTGADYDA 377
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G++IQPT+ V +DM +A EEIFGPV ++ F EVI AN++ YGLA ++T ++N
Sbjct: 378 GFFIQPTILVGVRNDMRVAYEEIFGPVLCVIPFKDEAEVIAMANDSEYGLAGAVWTQDIN 437
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
AL+ ++ VE G +WVN Y + APFGG+K SG+GRE +EAY ++K + +SL
Sbjct: 438 RALRVARAVETGRMWVNTYHEIPAHAPFGGYKKSGLGRETHKSMLEAYSQKKNIYVSL 495
>UniRef50_A2U9B6 Cluster: Aldehyde dehydrogenase; n=8; Bacteria|Rep:
Aldehyde dehydrogenase - Bacillus coagulans 36D1
Length = 499
Score = 356 bits (875), Expect = 8e-97
Identities = 195/479 (40%), Positives = 272/479 (56%), Gaps = 8/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K++I+ EW+DA + ET +P +G IA +G F+ + W
Sbjct: 12 KMYINGEWIDADNRETRAIKNPANGETIAIAPEGTTRDAHEAVDAARKAFE-SGIWSGIP 70
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A +R L++ AD I+ + + L +LE+ DNG + ++ RY L K G
Sbjct: 71 AQERAAYLFQVADKIDENAKALTRLETLDNGKPLREASYDIADAAACFRYYAGLITKPDG 130
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T + +++PVGVCGLI+PWN P+LM + K+ ALAAG T+V KP+E TP+T
Sbjct: 131 FTYHVADPMQAMVVREPVGVCGLIVPWNYPLLMSVWKIAPALAAGNTIVFKPSEVTPVTA 190
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGK-LIQKAAGTN 247
+E G+PKGV N+V G G G + HP+V ISFTG + GK L+++AA T
Sbjct: 191 MKLFEIFEEIGLPKGVANMVMGAGPVVGEEIVTHPEVDMISFTGGTKTGKHLMRQAADT- 249
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
LK+V+LELGGKSP II DAD A+ YA G+F GQ+C A SR+ V+ +Y++FV
Sbjct: 250 -LKKVSLELGGKSPNIIFADADFETAVDYALYGIFSGAGQVCSAGSRILVEESLYERFVS 308
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI---G-T 363
VE A I+VG D T GP + E M KVL IE GK+EGA L GG R+ G
Sbjct: 309 HFVERAAKIKVGPGDDPDTEMGPLVSEEHMKKVLSYIEIGKQEGATLALGGNRLLENGLD 368
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GY++ P VF DV +M I +EEIFGPV I KF E + AN+T YGLA +F+ +
Sbjct: 369 KGYFVGPAVFVDVKQNMRIVQEEIFGPVVVIQKFKDEAEAVKLANDTVYGLAGAVFSNDG 428
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
AL+ K + +G W+N+Y ++AP+GG+K SGIGR G +E + E K + I+L
Sbjct: 429 AKALRVIKKIRSGITWINSYHPTYNEAPWGGYKQSGIGRSLGTFGLEEFQEIKQININL 487
>UniRef50_A0JW23 Cluster: Aldehyde dehydrogenase (NAD(+)); n=1;
Arthrobacter sp. FB24|Rep: Aldehyde dehydrogenase
(NAD(+)) - Arthrobacter sp. (strain FB24)
Length = 505
Score = 355 bits (874), Expect = 1e-96
Identities = 197/478 (41%), Positives = 270/478 (56%), Gaps = 7/478 (1%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E Y + ID E A+ G+TF SP + +G R
Sbjct: 12 EPTYRPMIIDGEDAQAQSGQTFTRLSPAHEVEVTSFPEGGHEDVNRAVTAARKALDRG-- 69
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
WR + S+R KLL K ADL+ RD E L+ E+ + G +SG + Y SLA
Sbjct: 70 WRQSTGSERSKLLLKVADLVRRDAEALSLAETLETGKPITQSRNEVSGTAELWEYAASLA 129
Query: 124 DKIQGDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
GD G D+ + + +P+GV G+I PWN P+L+ K+ ALAAG T V+KP+E
Sbjct: 130 RNTHGDAHNALGQDTLAMVVHEPIGVVGMITPWNFPLLIISQKLPFALAAGNTAVIKPSE 189
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
T T +EAG P GVVNIV G G G A+ HP + ISFTGS VGK I
Sbjct: 190 STSATTVMLGQLIREAGFPAGVVNIVTG-GRVVGAAIAEHPGIDMISFTGSTGVGKGIAS 248
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +LK+V LELGGK+P II +AD A+ G +F+ GQ C + SRL V I
Sbjct: 249 AAG-RDLKKVELELGGKNPQIITANADFTAAVDAGVFGGYFNVGQCCNSGSRLIVHRSIA 307
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+F VE A+ +RVG+P T+ G ++++ + V + G+ GA+LL GG+R+
Sbjct: 308 DEFASAVVERAQHMRVGDPLKAETLVGSLVNDAQLAVVERYVAEGRDAGAHLLTGGDRLD 367
Query: 363 TA--GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
T G + QPTVF DV MTIA +EIFGPV S+L +DTLEE I AN+T++GL+AGI++
Sbjct: 368 TGLNGRFYQPTVFTDVTAHMTIATDEIFGPVLSVLPYDTLEEAIGIANSTSFGLSAGIWS 427
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL ++ + AGTVWVN ++ + PFGG+ SGIGRE G +A+ + E KT+
Sbjct: 428 NDINEALTAARDLRAGTVWVNRWMDGYPEVPFGGYGHSGIGRELGRQALAEFSELKTI 485
>UniRef50_Q57EI0 Cluster: Betaine aldehyde dehydrogenase; n=47;
Bacteria|Rep: Betaine aldehyde dehydrogenase - Brucella
abortus
Length = 487
Score = 355 bits (874), Expect = 1e-96
Identities = 192/479 (40%), Positives = 273/479 (56%), Gaps = 11/479 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI +V+ K G+ P G IA + + EW
Sbjct: 10 FIGGAFVEDKAGKPLPVIYPATGEEIASL---YSATPGIIEAAYAAALKAQGEWAALKPV 66
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGD 129
+RG++L + A+++ L+KLE+ D G + L + D++ + G + G+
Sbjct: 67 ERGRILRRTAEILREKNRKLSKLETLDTGKALQETLVADAASAADALEFFGGIISGFNGE 126
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+ G SF+YT ++ +G+C I WN PI + K ALA G + KP+E TPL+
Sbjct: 127 FVELGG-SFAYTRREALGICVGIGAWNYPIQIAAWKSAPALAMGNAFIFKPSENTPLSAL 185
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
KEAG+P G+ N+V G+G D G AL +H AK+S TGS+ G+ I AG L
Sbjct: 186 ALAEAYKEAGLPDGLFNVVQGYG-DVGAALVNHRLTAKVSLTGSVPTGRRIMAQAG-EQL 243
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K VT+ELGGKSPLI+ +DADL AI A G F+ GQ+C +R++V I ++F++
Sbjct: 244 KHVTMELGGKSPLIVFDDADLESAIGGAMLGNFYSTGQVCSNGTRVFVHKNIRERFIERL 303
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG---ERIG-TAG 365
VE + IR+G+PFDE+T GP I + +KVL I+ GK EGA L GG + G G
Sbjct: 304 VERTRKIRIGDPFDEATQMGPLISAAQRDKVLSYIKKGKAEGATLACGGGVPKLQGFDKG 363
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
++I+PTVFADV D MTIA+EEIFGPV S+L+F +EVI RAN++ +GLAAG+FT +L+
Sbjct: 364 FFIEPTVFADVTDTMTIAREEIFGPVMSVLEFSDEDEVIARANDSEFGLAAGVFTADLSR 423
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPK 484
++AGT W+N Y + PFGG+K SGIGRENGI A+ Y + KTV + + K
Sbjct: 424 GHHVIGQIKAGTCWINAYNLTPVEVPFGGYKQSGIGRENGIAALAHYSQIKTVYVEMGK 482
>UniRef50_Q0SDC1 Cluster: Aldehyde dehydrogenase; n=10;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 508
Score = 354 bits (870), Expect = 3e-96
Identities = 201/492 (40%), Positives = 285/492 (57%), Gaps = 20/492 (4%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
YT+ FID +WVD TFD P +G ++A A+G R EWR
Sbjct: 7 YTQ-FIDGQWVDTD--RTFDIIDPANGELVATAARGSVENLDQAVAAAKAAHARG-EWRT 62
Query: 67 ADASQRGKLLYKF-ADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
+R +L ADL ER E L L +NG+ + + G S+ +L AD
Sbjct: 63 KTPDERADILSAIVADLSER-MEELVALHVKENGVTIRQAMAFHVGY--SISHLQYFADL 119
Query: 126 IQGDTIPTDGDSFSY-TL------KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVV 178
+ G SY TL ++P+GV I+PWN P+L+ + K+ ALAAG T+V+
Sbjct: 120 ARTYEFERSGPQLSYPTLASGIVRREPIGVVAGIVPWNFPLLLAVWKLGPALAAGNTIVL 179
Query: 179 KPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGK 238
KP E+TPLT + AG+PKGV+NIV G GE+ G L HPDV KI+FTGS VG+
Sbjct: 180 KPDEKTPLTLLELAKSAERAGLPKGVLNIVTGAGEEVGARLAAHPDVRKIAFTGSTAVGR 239
Query: 239 LIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQ 298
I K A N+K+VTLELGGK P I++ DAD++ A+ A F + GQ C + +RL +
Sbjct: 240 EISKLAA-ENIKKVTLELGGKGPNIVLADADIDSAVDGALFACFLYAGQACESGTRLLLP 298
Query: 299 SGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG 358
++D+FV V+ A I+VG+P + T GP I ++L IE G+KEGA L GG
Sbjct: 299 ESLHDEFVDRLVQRAATIKVGDPSEFDTDIGPVISAEQHARILDYIEIGQKEGATLAFGG 358
Query: 359 ER-IGTA---GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGL 414
E GT G++++PT+F DV DM IA+EEIFGPV S+LK+ T++E + AN++ YGL
Sbjct: 359 EPPTGTQFEQGHWVRPTIFTDVTPDMRIAREEIFGPVLSVLKYRTVDEAVAIANDSEYGL 418
Query: 415 AAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLE 474
+AG+++ +L AL + +E+GTVW+N++ + PFGG+K SG GRE G A++ Y E
Sbjct: 419 SAGVWSEDLEAALVVAARIESGTVWINDWHMVNALYPFGGYKQSGNGRELGPHALDEYTE 478
Query: 475 EKTVIISLPKKL 486
EK V + L + +
Sbjct: 479 EKFVHVDLSRSV 490
>UniRef50_Q11KV7 Cluster: Aldehyde dehydrogenase; n=13;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 504
Score = 353 bits (867), Expect = 8e-96
Identities = 187/475 (39%), Positives = 277/475 (58%), Gaps = 10/475 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+ FI ++DA DG++FD +P G V+ K+A + F + W D
Sbjct: 24 RAFIGGRYIDAADGDSFDCINPATGRVLGKIASCKSTDIDLAVRSARRAFDGGA-WSCCD 82
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RYLGSLADK 125
S+R K+L + ADLIE + LA LE+ D G + ++ + + IP S R+ G DK
Sbjct: 83 PSERRKVLIRLADLIEAARDELALLETLDTGKLIRDSVTL--DIPSSAAVFRFYGEACDK 140
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
+ + +P +F+ K+PVGV G ++PWN P+ M K ALA G +VV+KPAEQ+P
Sbjct: 141 LLHEVVPVGPYAFASITKEPVGVVGAVIPWNFPLKMAAWKCAPALAVGNSVVLKPAEQSP 200
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT EAG+P+GV N+VPGFG +AG A+ H + + FTGS E+GK AG
Sbjct: 201 LTALKLAQLAVEAGVPEGVFNVVPGFGPEAGAAIGLHSGIDCVGFTGSTEIGKRFLAYAG 260
Query: 246 TNNLKRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+N+KRV LE GGKS I+ DA +L A A G+FF+QG++C A SRL+V + D
Sbjct: 261 QSNMKRVWLECGGKSACIVFPDAKNLEAAAKAAALGIFFNQGEVCSATSRLFVHRDLLDD 320
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI--G 362
F VE + + + G+P + S+ G I E +V+ IE GK+E A+L+AGG R+
Sbjct: 321 FTTLLVEASNSFKPGDPLEVSSGMGSMISEEQTTRVMSYIEKGKEE-ADLIAGGSRVLQE 379
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
T GY+I+PT+F +V+ IA EEIFGPV SI+ F + E ++ AN + YGL A ++T +
Sbjct: 380 TGGYFIEPTIFRNVDPRSVIACEEIFGPVLSIIPFGSESEAVELANASIYGLGASVWTGD 439
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
L+ A + S+ + AG++ +N + + PFGG K SG GR+ + A++ Y + KT
Sbjct: 440 LDRAFRLSRRLHAGSISINAVDHVDLRTPFGGVKQSGNGRDLSLHALDKYCDLKT 494
>UniRef50_A3Q3X2 Cluster: Aldehyde dehydrogenase; n=11;
Bacteria|Rep: Aldehyde dehydrogenase - Mycobacterium sp.
(strain JLS)
Length = 496
Score = 353 bits (867), Expect = 8e-96
Identities = 185/476 (38%), Positives = 266/476 (55%), Gaps = 5/476 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L I E A G T+D+ P+ G A+V G + W
Sbjct: 13 ELLIGGEPAAAASGATYDSVDPYTGRPWARVPDGGSADVDRAVAAARAALE--GPWGTLT 70
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A+ RGKLL++ ++I RD E LA+LE D G + + + + +P+ Y LADK+QG
Sbjct: 71 ATARGKLLWRLGEIIARDAEQLAELEVRDGGKLIREMVSQMRSLPEYYFYYAGLADKLQG 130
Query: 129 DTIPTDGDSFS-YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+ +PTD ++ YT +PVGV I PWN P+L+ K+ LAAGCT VVKP++ TP +
Sbjct: 131 EVVPTDKPNYLVYTRHEPVGVVAAITPWNSPLLLLTWKLAAGLAAGCTFVVKPSDHTPAS 190
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAG P GV+N+V G+G + G AL HP V K++FTGS G + KAA
Sbjct: 191 TLAFAKLFAEAGFPPGVINVVTGWGPETGAALASHPGVDKVAFTGSTATGIQVGKAA-IE 249
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
N+ R +LELGGKS ++ +DADL+ A +GVF GQ C+A SRL V + D V+
Sbjct: 250 NMTRFSLELGGKSAQVVFDDADLDAAANGVIAGVFAATGQTCLAGSRLLVHESVADALVE 309
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-TAGY 366
VE A I++G+P D +T GP ++ KVL + +++GA + GGE G
Sbjct: 310 RIVERAATIKLGDPKDPTTEMGPVSNQPQYEKVLSHFASAREQGATVAYGGEPAAELGGL 369
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+++PTV V+ M EEIFGPV +++ F +E + AN + +GLA ++T +++ A
Sbjct: 370 FVKPTVLTGVDPSMRAVAEEIFGPVLAVMTFTDEDEAVAAANASEFGLAGAVWTKDVHRA 429
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ + + AGTVWVN Y +A PFGG SGIGRENGI AV+ + E K V + L
Sbjct: 430 HRVAAKLRAGTVWVNAYRVVAPHVPFGGVGYSGIGRENGIDAVKDFTETKAVWVEL 485
>UniRef50_P23883 Cluster: Gamma-glutamyl-gamma-aminobutyraldehyde
dehydrogenase; n=57; Bacteria|Rep:
Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase -
Escherichia coli (strain K12)
Length = 495
Score = 352 bits (865), Expect = 1e-95
Identities = 183/476 (38%), Positives = 285/476 (59%), Gaps = 5/476 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI+ E+ A + ETF+T P + +AK+A+G+ F+R +W L+
Sbjct: 21 RLFINGEYTAAAENETFETVDPVTQAPLAKIARGKSVDIDRAMSAARGVFERG-DWSLSS 79
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQ 127
++R +L K ADL+E E LA LE+ D G ++ LR + G ++R+ DK+
Sbjct: 80 PAKRKAVLNKLADLMEAHAEELALLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVY 139
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G+ T + +++PVGV I+PWN P+L+ K+ ALAAG +V++KP+E++PL+
Sbjct: 140 GEVATTSSHELAMIVREPVGVIAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLS 199
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
KEAG+P GV+N+V GFG +AG AL+ H D+ I+FTGS GK + K AG +
Sbjct: 200 AIRLAGLAKEAGLPDGVLNVVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDS 259
Query: 248 NLKRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N+KRV LE GGKS I+ D DL A +G+F++QGQ+C+A +RL ++ I D+F+
Sbjct: 260 NMKRVWLEAGGKSANIVFADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFL 319
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ A+ + G+P D +T G ID + + V I G+ +G LL G G A
Sbjct: 320 ALLKQQAQNWQPGHPLDPATTMGTLIDCAHADSVHSFIREGESKG-QLLLDGRNAGLAA- 377
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
I PT+F DV+ + ++++EEIFGPV + +F + E+ + AN++ YGL A ++T +L+ A
Sbjct: 378 AIGPTIFVDVDPNASLSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRA 437
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ S+ ++AG+V+VNNY PFGG+K SG GR+ + A+E + E KT+ ISL
Sbjct: 438 HRMSRRLKAGSVFVNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISL 493
>UniRef50_Q75TI0 Cluster: Glycine betaine aldehyde dehydrogenase;
n=1; Geobacillus stearothermophilus|Rep: Glycine betaine
aldehyde dehydrogenase - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 482
Score = 351 bits (864), Expect = 2e-95
Identities = 189/472 (40%), Positives = 272/472 (57%), Gaps = 4/472 (0%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
++++ +W +G+ +P + +I ++ + FQ ++W A
Sbjct: 2 IYVNGKWSKG-EGKKRPVINPANEEIIIEINEASQQQAVEAIQAARHAFQY-TDWPFNPA 59
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+R L + ADL+E++ E A +E+ + G + +S +RY ++ +
Sbjct: 60 -KRIAALRQLADLLEQNAETFASIETLNTGKPIRESRLDVSDSIQCLRYYADFVEQRAIE 118
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
I + S +++P+GVC LI+PWN P+L+ + K+ ALAAG TVV KP+E TPL+
Sbjct: 119 EIKRTDGTTSKIIEEPIGVCALIVPWNFPLLLGIWKLAPALAAGNTVVFKPSELTPLSFI 178
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
G+P GV N+VPG G G L HPDV KISFTG + G+ I + G L
Sbjct: 179 ELTKLIDSIGLPPGVFNLVPGGGSPVGETLVTHPDVEKISFTGGTKTGRWIYEQ-GARRL 237
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KRV+LELGGKSPL+I +DADL I +A FF+QG++CVAASR+ VQ +YD F+
Sbjct: 238 KRVSLELGGKSPLLIFDDADLASTIEWALFASFFNQGEVCVAASRILVQRRVYDSFLDQL 297
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
+ ++R+G+PF E T GP I S + KV I+ G +EG LL GG+R+ GYY+
Sbjct: 298 TQRLASLRIGDPFAEHTEMGPLISSSHLEKVETYIQIGLQEGGVLLQGGKRMKELGYYLT 357
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
P VFA V DM I +EEIFGPV ++ F+ EE I AN+T YGLAAG+F+ +L A Q
Sbjct: 358 PAVFAHVRQDMRIVQEEIFGPVITVQPFEHDEEAIKLANDTIYGLAAGLFSRDLERAEQI 417
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+ + AGT+W+N+Y T AP+GG K SGIGRE G + A+ E K V IS
Sbjct: 418 AGKLRAGTIWINSYHTPYVDAPWGGLKQSGIGRELGPQGFAAFTETKHVNIS 469
>UniRef50_Q3YAT5 Cluster: Hydroxyisobutyraldehyde dehydrogenase;
n=1; Mycobacterium austroafricanum|Rep:
Hydroxyisobutyraldehyde dehydrogenase - Mycobacterium
austroafricanum
Length = 504
Score = 351 bits (864), Expect = 2e-95
Identities = 177/475 (37%), Positives = 270/475 (56%), Gaps = 6/475 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
++++ EW+ A+ G TF T P G I ++ +G EW+ DA
Sbjct: 19 MYVNGEWLPARSGATFPTIEPSTGRPITEIPRGDSSDVDAAVKAAADVAV---EWQFTDA 75
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
R LL + A+L+ + E LA++ES D+G +++ IP + Y ADK+ G
Sbjct: 76 ITRAALLRRLAELVAENAEELARIESLDSGHYLAKARELVTAIPLWLEYWAGAADKVGGR 135
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
TI G+ S+TL +P+GV I+PWN P+L+ + ALA G T VVKPAE T L+
Sbjct: 136 TIAVPGNKLSFTLLEPLGVTAHIIPWNYPLLILARSIAPALALGNTCVVKPAEDTSLSAL 195
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
AG P GV N+V G+G +AG AL HP+V I+FTGS E G+ I + G ++
Sbjct: 196 KFAELVHAAGFPAGVFNVVTGYGSEAGAALAAHPEVRGITFTGSTETGREIARLGG-QHI 254
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
+V LELGGKSPL++ DA L A+ A G GQ+CVA SRL++ I D+F++
Sbjct: 255 AQVNLELGGKSPLVVFPDAPLEDAVEVAVQGFCSRAGQVCVAGSRLFLHEDIADRFLEML 314
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--GYY 367
V + + VG+PFD +T GP + ++V IE GK+E L GG T G++
Sbjct: 315 VSRLETVTVGDPFDGATQMGPLASKKHYDRVREYIEVGKQEATLLYGGGRPTDTPDDGFF 374
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
++PTVF DV D IA+EEIFGPV +++++ +++++I N++ +GL A ++ ++ +AL
Sbjct: 375 VEPTVFVDVATDARIAREEIFGPVTAVMRWSSVDDLIATINDSEFGLFAVLWCRDITSAL 434
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+K ++ G+V +N++ P GG K SG GRE G++AV Y + K + I+L
Sbjct: 435 DTAKRLQVGSVMINDWFGELPMTPHGGHKQSGTGREEGLEAVHGYTQVKHIGINL 489
>UniRef50_Q9L397 Cluster: FldD protein; n=1; Sphingomonas sp.
LB126|Rep: FldD protein - Sphingomonas sp. LB126
Length = 504
Score = 351 bits (863), Expect = 2e-95
Identities = 187/461 (40%), Positives = 266/461 (57%), Gaps = 11/461 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ W +A GE +P I +A G F+ ++EW A+
Sbjct: 25 FINGLW-EAGSGEPIAVVNPATEQPIGSIAAGGEAEVDRAVAAARQRFE-SAEWTRMPAA 82
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDS-VRYLGSLADKIQGD 129
+R +LL + ADL+ERD + LA +E+ DNGM + + G S +RY A ++ G+
Sbjct: 83 ERERLLLRLADLVERDRDELAAIETLDNGMPFAPARMMAVGSAISAIRYNAGWARRMTGE 142
Query: 130 TIPTD--GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
P G YT ++P+GV LI+PWN P + NKV ALAAGCTVV+KPAE P++
Sbjct: 143 EAPVSVPGRWHGYTSREPLGVAALIVPWNAPFAITCNKVSAALAAGCTVVLKPAELAPMS 202
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGK-LIQKAAGT 246
+EAG P G +N+V G G AG AL HP V KISFTGS G+ ++++ AG
Sbjct: 203 GLRLAELVQEAGFPDGCLNVVTGLGAQAGAALVRHPGVDKISFTGSTATGQSILRETAG- 261
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
L RV+LELGGKS +++ DADL AIP G+F + GQ+C A SRL++ ++D+FV
Sbjct: 262 -RLTRVSLELGGKSAVLVFPDADLEKAIPAVAMGIFGNSGQVCAAGSRLFLHDSVFDRFV 320
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
G V++A+ + VG GP I +V+G I G+ EGA + G GY
Sbjct: 321 TGLVDFAEKLMVGPGDQPGVALGPLISAGQKERVMGYIAAGEAEGAQIATRGSAPDEPGY 380
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTTNLN 424
+++PT+F D DM I +EEIFGPV S+++F D LE + +AN++ YGL+A ++T +L+
Sbjct: 381 FVKPTIFVDTRPDMRIVREEIFGPVLSVMRFSDDNLENLARQANDSIYGLSAYVWTRDLS 440
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENG 465
A ++++ AG+V VN M PFGGFK SGIGRENG
Sbjct: 441 TAHAMARYLRAGSVKVNG-SGMEFALPFGGFKQSGIGRENG 480
>UniRef50_Q5KYB4 Cluster: Aldehyde dehydrogenase; n=8;
Bacillaceae|Rep: Aldehyde dehydrogenase - Geobacillus
kaustophilus
Length = 505
Score = 350 bits (860), Expect = 6e-95
Identities = 185/475 (38%), Positives = 272/475 (57%), Gaps = 8/475 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L ++ E V++ GETF +P G +A+VAKG F R +WR
Sbjct: 21 LIVNGERVESASGETFVVTNPATGEPVARVAKGTREDAERAVQAARQAFDRG-KWRHFPV 79
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL-RILSGIPDSVRYLGSLADKIQG 128
+R ++LY+ A ++ F L +LE + G +++ I D + G++ +G
Sbjct: 80 QKRARILYQIAAIMRERFNELVELEILNTGKALSAAQGQVMQAIEDFEFFAGAIIGH-RG 138
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
P G +YT K+PVGVC I+PWN P++M K+ A+AAGC+VVVKPA TPLT
Sbjct: 139 AVNPMPGAFHNYTEKEPVGVCAQIIPWNYPLMMAAWKIAPAIAAGCSVVVKPASLTPLTC 198
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
EAG+P+GVVN+V G G + G L HP V K++FTGS VGK I + A +
Sbjct: 199 LVLAEICHEAGVPEGVVNVVTGAGAEVGDYLVEHPLVDKVAFTGSTPVGKEIMEKA-SKT 257
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LKRVTLELGGKSP ++ DADL A+ + G+F++ GQ C A SRLYV IYD F++
Sbjct: 258 LKRVTLELGGKSPSLVFADADLEAAVAGSLFGIFYNSGQSCEARSRLYVHESIYDAFMEA 317
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---- 364
V K +++G+PFD T G I + + +++ +GA + AGG+ A
Sbjct: 318 FVAKTKQLKLGDPFDAGTHVGAIISRGQLEVIDEYVQSAVADGATVAAGGKEAVVAGFEN 377
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GY+ +PT+ +VN M +EEIFGPV ++KF E I+ AN+++YGLAA I+T +
Sbjct: 378 GYWYEPTILTNVNHQMKAVREEIFGPVVVVMKFRDEAEAIELANDSDYGLAAAIWTKDHG 437
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
A++ +K + +G V VN+ + PFGG+K SG GRE ++A++ Y E K+V+
Sbjct: 438 RAVRVAKQLRSGIVMVNSPFSAFPGTPFGGYKQSGFGRELSVEALDLYTETKSVL 492
>UniRef50_Q11K71 Cluster: Aldehyde dehydrogenase; n=2;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 500
Score = 349 bits (859), Expect = 7e-95
Identities = 188/472 (39%), Positives = 270/472 (57%), Gaps = 9/472 (1%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
I E V A DGET+ T +P +G + G+ + W ++
Sbjct: 10 IGGEAVAAADGETYITHNPANGRPWGRFPAGKSADVARAVAAAMEALR--GSWGSMAPTR 67
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTI 131
RG+LL ++A I + E +A+LE+ NG ++++CL + + + Y G ADKI+G +
Sbjct: 68 RGRLLIEWARAISVNAEKIARLETAQNGKIFRDCLNQARDLENWLYYYGGQADKIEGTVV 127
Query: 132 PTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
P S +YTL++P+GV G+I PWN P + ++ ALAAG +V+KP+E TP +
Sbjct: 128 PLLRQSILNYTLREPLGVIGIITPWNSPASLTMSSAAPALAAGNAIVIKPSEVTPASILE 187
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+EAGIPKGV+N+V G G +AG AL HPD+AKI+FTGS+E G+ I + AG L
Sbjct: 188 IARLAEEAGIPKGVINVVTG-GRNAGEALVDHPDIAKIAFTGSVEAGRAIAERAG-KRLI 245
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
TLELGGKSP I+ DADL A G+F GQ CVA SR YV ++D FV+
Sbjct: 246 GCTLELGGKSPNIVFPDADLARAEAGVLGGIFASTGQTCVAGSRAYVHESLFDSFVERLA 305
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG----Y 366
A+ I +G+P D T GP E + K L+ EGA +AGGER+ G Y
Sbjct: 306 TRARQIVLGDPMDPRTQMGPVSTELQLQKDERLVAEALSEGAVKIAGGERVSPPGCEDGY 365
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ PTV +N +I K E+FGPV S+L F + ++V+ AN++ +GLAAG +T + A
Sbjct: 366 FYAPTVLTKLNPAASILKTEVFGPVLSVLPFKSEDDVVAMANDSPFGLAAGFWTRDFARA 425
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +EAGTVW+N Y A +P G K SGIG +NG +A+ YL+ K+V
Sbjct: 426 HRLARRLEAGTVWINMYRAFAFNSPMNGHKQSGIGWQNGSEAIFQYLKTKSV 477
>UniRef50_Q6D6E0 Cluster: Betaine aldehyde dehydrogenase; n=127;
cellular organisms|Rep: Betaine aldehyde dehydrogenase -
Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 490
Score = 348 bits (856), Expect = 2e-94
Identities = 187/480 (38%), Positives = 268/480 (55%), Gaps = 10/480 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L+I+ +VD+ +TFD +P +G +IA + Q W
Sbjct: 8 QLYINGAYVDSTGNDTFDAVNPANGDIIACI---QSATAADVDRAVSAATAGQKVWAAMT 64
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNG--MVYKNCLRILSGIPDSVRYLGSLADKI 126
A +R ++L + D++ + LA LE++D G + + I++G D + Y L +
Sbjct: 65 AMERSRILRRAVDILRERNDELALLETHDTGKPLSETRTVDIVTGA-DVLEYYAGLIPML 123
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
+G IP SF YT ++P+GV I WN PI + L K ALAAG ++ KP+E T L
Sbjct: 124 EGQQIPLRDTSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSL 183
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T EAG+P GV N++ G G+ G ALT HP +AK+SFTG + GK + A
Sbjct: 184 TALKLAEIYTEAGLPAGVFNVLTGTGKSVGQALTTHPGIAKVSFTGGIASGKTVMANAAG 243
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ LK VT+ELGGKSPLII +DADL+ A A FF GQ+C +R++V + +F
Sbjct: 244 STLKDVTMELGGKSPLIIFDDADLDKAADIAMMANFFSSGQVCTNGTRVFVPKALQAQFE 303
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ + + IR G+P DES GP + VL IE+GK+EGA +L GGE + Y
Sbjct: 304 EKILACVQRIRAGDPTDESVNFGPLVSFPHRESVLRYIESGKREGARVLVGGEPMTDGDY 363
Query: 367 ----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
Y+ PTVF D DDM I ++EIFGPV SIL + +EVI RAN++ YGLAAGI T +
Sbjct: 364 AQGAYVAPTVFTDCRDDMKIVRKEIFGPVMSILTYQDEDEVIRRANDSEYGLAAGIVTRD 423
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
LN A + +EAG W+N + + P GG+K SG+GRENG+ +E Y + K++ + L
Sbjct: 424 LNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGVGRENGVTTLEHYTQIKSIQVEL 483
>UniRef50_Q0SJZ2 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|Rep:
Aldehyde dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 478
Score = 348 bits (855), Expect = 2e-94
Identities = 185/468 (39%), Positives = 262/468 (55%), Gaps = 9/468 (1%)
Query: 19 AKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYK 78
+K G+ F T P G VIA+VA G F+ WR A+ RG++L +
Sbjct: 16 SKSGQYFSTRDPATGDVIAEVALGGAEDIEAAVAVAQSAFR---SWRDTPAATRGRILLE 72
Query: 79 FADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSF 138
A + + LA++E+ D G + Y G ADK+ G+TIP D
Sbjct: 73 VARTLREHADELARIETLDTGQTLSQSNVDIETAARYFEYYGGAADKVHGETIPLGPDYL 132
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
SYT +P GV G++ PWN PI + ALA G VV+KPAE TPL+ EA
Sbjct: 133 SYTRNEPFGVIGVVTPWNAPINQAARAIAPALAMGNVVVLKPAEDTPLSALEMSRLAVEA 192
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
G+P GV+N+VPGFG DAG ALT H V KI FTGS+E G+ I +AA L +TLELGG
Sbjct: 193 GLPAGVLNVVPGFGADAGAALTGHDKVRKIVFTGSVETGRAIMRAA-AQRLIPLTLELGG 251
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I+ +DADL+ A A + GQ+C A SRL V S ++D+ V V++AK +
Sbjct: 252 KSPNIVFDDADLDAAATGAWTAFTTKAGQVCSAGSRLLVHSSVHDELVGRLVQHAKTTVI 311
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----GYYIQPTVFA 374
++ + G +KV +E G EGA + GG T G +I+PT+F
Sbjct: 312 APGIEDPDI-GSLATRGQFDKVRSYLELGPSEGARVATGGHVADTGRLGRGLFIEPTIFV 370
Query: 375 DVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVE 434
DV++ M +A+EEIFGPV ++L+FD+ EE ++ AN+++YGL AG++T + A + + +E
Sbjct: 371 DVDNTMRVAREEIFGPVLTVLRFDSDEEAVEIANDSDYGLVAGVWTRDHGRAHRVAGAIE 430
Query: 435 AGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
AG V++N Y + PFGG+K SG GRE G +A++ Y + KT+ L
Sbjct: 431 AGQVFINQYFAGGVETPFGGYKLSGFGREKGFEALKHYCQLKTITARL 478
>UniRef50_Q0UEE3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 490
Score = 348 bits (855), Expect = 2e-94
Identities = 187/480 (38%), Positives = 272/480 (56%), Gaps = 10/480 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAK-VAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
+LFI+NE+VD+K+ + ++P DGS+++ V F W+
Sbjct: 13 QLFINNEYVDSKNSKKLTLYNPKDGSLVSNDVPLAGEQDVDAAVEAAEKAFPA---WKKM 69
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL---RILSGIPDSVRYLGSLAD 124
A+QR +L KFADLIE+ +A+L G + + + RY D
Sbjct: 70 GATQRRNILLKFADLIEKHANEIAQLSRISLGAPASFGAFEGGLCAESRQTFRYNAGFID 129
Query: 125 KIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
K G++ P + +P+GV I+PWN PI K ALA G ++KP+E+T
Sbjct: 130 KFGGESWPQEDGFLKIVRNEPLGVTAGIVPWNGPIGTIGLKAGPALATGNCFILKPSEKT 189
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P + KEAG P GV ++ G G G L H + K+SFTGS+ GK IQ+ A
Sbjct: 190 PFSSLALGTLIKEAGFPPGVFQVLSGDGS-TGALLASHMRIRKVSFTGSIATGKKIQEMA 248
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+NLKRVTLELGGKSP ++ +D +L A+ + + + + GQ+C AASR+YVQ GIY+K
Sbjct: 249 AKSNLKRVTLELGGKSPAVVFDDCNLENAVTWTANAITANTGQVCFAASRVYVQEGIYEK 308
Query: 305 FVKGAVEYAK--AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
F++ E K A +G+P E T GP +DE+ +V G IE G++ L GG+R+G
Sbjct: 309 FIERYKEAMKNKAKEIGDPEAEGTNMGPLVDEAQFKRVQGFIERGQQGQGTLAVGGKRVG 368
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G+YI+PTVF DV+ I EEIFGPV + F T EE+I+ +NNTN+GL AG+FT +
Sbjct: 369 DKGFYIEPTVFTDVDPKSEIHCEEIFGPVSVVKSFKTEEEIIELSNNTNFGLMAGVFTQD 428
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+N AL+ + ++G V +N M PFGG K+SG+GRE GI A+ A+ E KT++I++
Sbjct: 429 INKALRVASDFDSGMVGINCVSLMFTVTPFGGSKESGLGRECGIHALRAFTEPKTIMINM 488
>UniRef50_A1D0S9 Cluster: Aldehyde dehydrogenase; n=4;
Pezizomycotina|Rep: Aldehyde dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 550
Score = 347 bits (852), Expect = 5e-94
Identities = 189/484 (39%), Positives = 276/484 (57%), Gaps = 9/484 (1%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PEI+ T+LFID E+V + DG F +P G +A+V++ + F
Sbjct: 71 PEIE-TRLFIDGEFVPSLDGSKFKVTNPFTGETVAEVSEAKAEDVNRAVESAKRVFPT-- 127
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
W D S R +L+ + ADL++ A+LE+ G + + G ++RY
Sbjct: 128 -WSGLDGSDRRRLMLRLADLVDEHAAEFARLEALSMGKPVSTYMDQVMGTA-TLRYYAGK 185
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
A I G T T + + +++QP GV G I+PWNVP++M KV AL AG T+V+K +E
Sbjct: 186 ALDIHGVTSLTSKNHLNISIRQPYGVTGAIIPWNVPVIMICFKVGPALIAGNTLVLKSSE 245
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
+ PLT KEAG P GV+N++ GFG G A+ H D+ KI+FTGS + GKLIQK
Sbjct: 246 KAPLTSLLFARLAKEAGFPPGVLNVLSGFGLPCGDAIARHMDIRKIAFTGSTKTGKLIQK 305
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AA +NLK TLELGGKSPLI+ DADL A A + F+ GQ+C+A+SR+Y+Q +
Sbjct: 306 AAVDSNLKSCTLELGGKSPLIVFEDADLEKAAKVAAFSIVFNSGQVCMASSRVYIQENVA 365
Query: 303 DKFVKGAVEYAKAI--RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
D+F K + +A+ + GNP + +T GPQ D+ + ++ +K+G L GE
Sbjct: 366 DQFKKLYAQAIQAVAGQAGNPLEATTGFGPQADKQQFESISKYLQEAQKDGLKRLPIGEL 425
Query: 361 I-GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
G ++ P VF DV +D +I K+EIFG V + F + ++VI AN++ YGL A +F
Sbjct: 426 TPRDGGNFVSPIVFHDVPEDHSIMKDEIFGAVSCLNTFSSEDDVIRAANDSEYGLYASVF 485
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLT-MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
T ++N A++ +K EAG++ VN P GGFK SG GRE G + +EA+ E K++
Sbjct: 486 TRDINRAIRVAKCFEAGSIGVNTSSPYYCQDLPLGGFKGSGTGRELGDEGLEAWTEVKSI 545
Query: 479 IISL 482
ISL
Sbjct: 546 YISL 549
>UniRef50_Q0SFT2 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 498
Score = 345 bits (848), Expect = 2e-93
Identities = 184/476 (38%), Positives = 266/476 (55%), Gaps = 3/476 (0%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFID + AK ETFD+ +P G ++A+VA F + W +
Sbjct: 22 ELFIDGAFRPAKSDETFDSINPATGELLARVAAADAPDVDAAVRSAREAFD-SGVWSRSP 80
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQ 127
AS R ++L + A+LI LA L+S D G + L + + D R+ DKI
Sbjct: 81 ASHRKRVLLRLAELILEHRHELALLDSLDMGKLVVEALTVDVPSAADLFRFYAEALDKIG 140
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G+ PTD S + ++P+GV G ++PWN P+ + + K+ ALAAG +VV+KPAEQ PL+
Sbjct: 141 GEIAPTDPGSLALVSREPLGVVGAVVPWNFPLDLAVWKLAPALAAGNSVVLKPAEQAPLS 200
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAG+P GV+ +VPGFG AG AL HPD+ ++FTGS GK + A +
Sbjct: 201 VLRLAELAAEAGLPDGVLGVVPGFGATAGAALGLHPDLDVLAFTGSTATGKRFLRYAADS 260
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NLK+V LE GGKSP ++ DADL+ A+ A G F++QG +C A SRL V+ + ++ +
Sbjct: 261 NLKQVWLECGGKSPNLVFADADLDEAVEKAVFGAFYNQGAVCSANSRLLVEESVAEQVTE 320
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE-RIGTAGY 366
V A +IR GNP D ++ G +DE+ V G I+ + EG LL G + + G
Sbjct: 321 ALVRRASSIRPGNPLDPASTLGAIVDENHARTVTGFIDRARSEGRVLLGGNKTTVDARGS 380
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+++PT+FADV + E+FGPV ++ F E + N++ YGLAA ++T NLN A
Sbjct: 381 FVEPTIFADVAPTAEVVTREVFGPVLTVQTFTDEAEAVRMGNDSIYGLAASVWTENLNRA 440
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ S + AGTV VN ++ Q PFGGFK SG GR+ + A + Y KT I L
Sbjct: 441 HRVSAALRAGTVSVNTVDAISAQTPFGGFKQSGFGRDLSLHATDKYTGLKTTWIRL 496
>UniRef50_Q0RKA3 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Frankia alni (strain ACN14a)
Length = 487
Score = 345 bits (847), Expect = 2e-93
Identities = 179/458 (39%), Positives = 252/458 (55%), Gaps = 3/458 (0%)
Query: 24 TFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLI 83
TFD+ P+ G A VA+ F EW +RG+L+ + A +I
Sbjct: 19 TFDSIDPYTGEAWATVAEASRADVDDAVAAARAAFD-GGEWSKLSGRERGRLMRRLAAVI 77
Query: 84 ERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG-DSFSYTL 142
E + L E+ DNG + + + + Y LADKI G + T D F +
Sbjct: 78 EEHADELGLAETRDNGKLLREMGGQVRSLSAWYEYYAGLADKIDGRVVDTGRPDYFGFVT 137
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
++P+GV G +LPWN P+L+ K+ ALAAGCT+V KP+EQ P++ +EAG P
Sbjct: 138 REPIGVVGAVLPWNSPLLLLTFKIAPALAAGCTIVAKPSEQAPVSILKFADLFEEAGFPP 197
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
GV N V G + G L HP V ++SFTGS G + AA +L VTLELGGKS
Sbjct: 198 GVFNTVSGASREVGEWLVGHPGVDRVSFTGSEITGAAVA-AAAAKHLAPVTLELGGKSAN 256
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
I+ DADL A +G+F GQ C+A SR V + +Y++ V E A IR+G+P
Sbjct: 257 IVFPDADLAAASNGLIAGIFAAAGQTCIAGSRALVHADVYEEVVARVAERAARIRLGDPK 316
Query: 323 DESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTI 382
D T GP K+ + K++GA+++ GG G G + +PT+ A+V +D +
Sbjct: 317 DPETEMGPICFPGQHEKIRRFVAQAKEQGADIVGGGGDGGLGGLFFEPTIVANVTNDAMV 376
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
+EEIFGPV S+L+F + EE I AN++ YGLAAGI+T ++ A + +K + GTVWVN
Sbjct: 377 CQEEIFGPVLSVLRFSSEEEAIAIANDSRYGLAAGIWTADIRRAFRMTKALRVGTVWVNA 436
Query: 443 YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
Y T+ + PFGG K SG GRENG + + YL+EK V I
Sbjct: 437 YRTLNYAMPFGGIKSSGFGRENGTEGLHEYLQEKAVWI 474
>UniRef50_A1B0W8 Cluster: Aldehyde dehydrogenase (NAD(+)); n=2;
cellular organisms|Rep: Aldehyde dehydrogenase (NAD(+))
- Paracoccus denitrificans (strain Pd 1222)
Length = 494
Score = 344 bits (845), Expect = 4e-93
Identities = 183/480 (38%), Positives = 266/480 (55%), Gaps = 7/480 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID GET SP G+ +A A G F+ + WR A+
Sbjct: 9 FIDGAERPGASGETIRRHSPAHGAALADFAAGTAEDLDAAVRAAREAFE-HGPWRQMPAT 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
Q+ +L + DLI D E LA +E+ ++G + + +RY +L ++ G+
Sbjct: 68 QKAAILNAWGDLIAADLERLAVIEAEESGKPIRFARGEIEHSVSMLRYAAALGMQLHGEA 127
Query: 131 IPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
G + ++P GV G+I+PWN P++ K+ ALAAGC+VVVKP+E T T
Sbjct: 128 FENVGPQALGLVSREPRGVVGMIVPWNFPMVTLFQKLPYALAAGCSVVVKPSELTSGTAL 187
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
AG+PKGV N+V G G G A+T HP+V ISFTGS +VGK I + +++
Sbjct: 188 EVAKLAIRAGLPKGVYNVVTGTGGAVGEAMTRHPEVDMISFTGSTKVGKAIARTCA-DSV 246
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KRV LELGGK+ ++ DADL+ A+ G +QG+ CV +RL ++ + D FV
Sbjct: 247 KRVALELGGKAANVVFADADLDAAVDGVLFGYVLNQGEECVCGARLLIEESVADAFVSRL 306
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----G 365
VE + IR G P DE I E+ ++V+ +E GK EGA + GG R G
Sbjct: 307 VERTRKIRTGLPLDEDADQAAMIHEAQFDQVMDYLEIGKAEGATVAVGGGRAEEGALAKG 366
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y++ PT+F DV+ DM I +EEIFGPV ++ F T++E + AN+T YGL G++T +L+
Sbjct: 367 YFVMPTIFTDVSPDMRIFREEIFGPVLTVTTFKTVDEAVTLANDTVYGLGNGLWTKDLDK 426
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
A+ ++ + +GTV+VN +L + Q PFGGFK SGIGRENGI + Y E K+ I L ++
Sbjct: 427 AILVARRLRSGTVFVNTFLETSVQMPFGGFKQSGIGRENGIDGLLEYTEVKSTFIKLGER 486
>UniRef50_Q5UWD2 Cluster: Aldehyde dehydrogenase; n=1; Haloarcula
marismortui|Rep: Aldehyde dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 483
Score = 344 bits (845), Expect = 4e-93
Identities = 183/477 (38%), Positives = 264/477 (55%), Gaps = 3/477 (0%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T L+I EW +A +G++ +T P A V K + SEW
Sbjct: 7 TDLYIGGEWREATNGDSIETEDPATERTYASVQKAEASDIDAAVEAAQAAVAEGSEWATM 66
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
D R L+ AD IE + L+ +ES+DNG + + D+ R+ DK++
Sbjct: 67 DPGTRRAKLHAMADAIEAMKDELSMVESHDNGKTPFEAGLEIDMVIDTFRHYAGWTDKVR 126
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
GD IP + +YT ++PVGV I PWN P + + ALA G +V++KP+ TPL+
Sbjct: 127 GDEIPVENGRLNYTTREPVGVTAHIAPWNYPFQLAGRGLAPALATGNSVILKPSAMTPLS 186
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+EAG+P GVVN+VPG G +AG ALT H V ++FTGS VGK +Q+ A +
Sbjct: 187 ALYYAKAAEEAGLPDGVVNVVPGKGSEAGDALTGHEGVDHVTFTGSTGVGKTVQRTA-AD 245
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
+ VTLELGGK P ++ DADL+ A G+F + GQ+C A SR+ V +Y++ V
Sbjct: 246 AVADVTLELGGKGPAVVFPDADLDAAARGIQYGIFMNAGQMCWANSRIVVHEDVYEEMVS 305
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--TAG 365
E A+ I +G D+ GP + ++L IETGK+EGA + AGG G G
Sbjct: 306 RMAEIAENIPLGGGIDDDGQMGPVVSAGQQQEILDYIETGKEEGATVAAGGGVPGDKETG 365
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
++++PTVFADV+++MTIA+EEIFGPV + ++ E ID AN++ +GL A ++T +L
Sbjct: 366 HFVEPTVFADVDNEMTIAQEEIFGPVLTAIEVSDEEAAIDVANDSPFGLTACVWTNDLTR 425
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + ++ G V VN Q PFGG K SG GR G +A+E+Y E K V I+L
Sbjct: 426 AHTVTDRLDYGMVMVNETPNTWPQTPFGGTKQSGHGRAQGEQAIESYTEVKNVHINL 482
>UniRef50_Q8EMH4 Cluster: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenase; n=4; Bacteria|Rep:
5-carboxymethyl-2-hydroxymuconate semialdehyde
dehydrogenase - Oceanobacillus iheyensis
Length = 507
Score = 343 bits (844), Expect = 5e-93
Identities = 180/476 (37%), Positives = 271/476 (56%), Gaps = 5/476 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KL+I+ E++DA+D TFD SP I VA GQ F+ EW
Sbjct: 25 KLYINGEFMDAEDRGTFDNISPFSNEKINSVASGQAADIDKAVQSAKKAFK--GEWGNLK 82
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVR-YLGSLADKIQ 127
+R + +YK DLIE+ + +A LES D G+ + +S ++ R Y ++ ++
Sbjct: 83 QVERLEYVYKIGDLIEQHTDEIAILESLDTGLPISQTRKQVSRSANNFRFYADTVKSQMY 142
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G+ D + +YT++ VGV GLI PWN P ++ K+ ALA G TV++KPAE +PLT
Sbjct: 143 GEVYQVDDEFINYTVRSAVGVAGLITPWNAPFMLETWKIAPALATGNTVILKPAEWSPLT 202
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+AG+P GV NIV GFGE AG AL HPDV ISFTG G I + G +
Sbjct: 203 ANRMAEIIDQAGLPDGVFNIVHGFGETAGDALVKHPDVQLISFTGETTTGSTIMR-NGAD 261
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
LKR ++ELGGKSP+I+ DADL A+ A G+F G+ C A SRLY+ I D+F++
Sbjct: 262 ALKRFSMELGGKSPIIVFEDADLERALDAATWGIFSFNGERCTANSRLYLHESIADEFIE 321
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-ERIGTAGY 366
+ IRVG+P + +T GP I N V ++ ++EG +++G + G
Sbjct: 322 KLKQRVWNIRVGDPLENNTQIGPLIKTEHYNNVKKYLKIAEEEGCEIISGVIPKELNRGN 381
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
Y+ PT+ + +++M + +EEIFGPV +++ F+ EVI++AN+ YGLA ++T ++
Sbjct: 382 YVAPTILLNASNEMRVVQEEIFGPVIAVMTFNDETEVIEKANDVRYGLAGYVWTNDMKRG 441
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ + +++G +WVN+ + PFGG KDSGIGRE G A E Y E+K + +++
Sbjct: 442 HRVAHAIDSGMLWVNSQNVRDLRTPFGGSKDSGIGREGGHYAFEFYTEQKIIHVAI 497
>UniRef50_Q5SJP9 Cluster: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenaseiheyensis HTE831]'; n=2;
Thermus thermophilus|Rep:
5-carboxymethyl-2-hydroxymuconate semialdehyde
dehydrogenaseiheyensis HTE831]' - Thermus thermophilus
(strain HB8 / ATCC 27634 / DSM 579)
Length = 515
Score = 343 bits (842), Expect = 8e-93
Identities = 191/481 (39%), Positives = 269/481 (55%), Gaps = 14/481 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI E+V ++ GETF + P V+ A+G FQR W A
Sbjct: 30 FIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQR---WSRTKAK 86
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD- 129
+R + L + A+LIE+ + LA +E D G V + ++ ++ + A+ D
Sbjct: 87 ERKRYLLRIAELIEKHADELAVMECLDAGQVLRIVRAQVARAAENFAFYAEYAEHAMEDR 146
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
T P D D YT++ P G G+I PWN P+++ ++ ALA G TVV+KPAE +P T
Sbjct: 147 TFPVDRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVLKPAEWSPFTAT 206
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
KEA +P GV N+V GFGE+AG AL HP V ++ TG E GK++ + A ++L
Sbjct: 207 KLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETETGKIVMRNA-ADHL 265
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KR++ ELGGKSP ++ DADL A+ +F G+ C A+SRL V+ I++ FV
Sbjct: 266 KRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVEEKIFEDFVGKV 325
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----- 364
VE A+AIRVG+P D T GP I + +VLG +E GK+EGA LL GGER T+
Sbjct: 326 VERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGGERAKTSFRGED 385
Query: 365 ---GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G Y+ PTVF N M IA+EEIFGPV + F EE + +AN+T YGLAA +FT
Sbjct: 386 LSRGNYLLPTVFVGEN-HMKIAQEEIFGPVLVAIPFKDEEEALRKANDTKYGLAAYVFTR 444
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L A + + +EAG V++N++ PFGG K SG RE G A++ Y + KT+ +
Sbjct: 445 DLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKGSGDRREGGTYALDFYTDLKTIALP 504
Query: 482 L 482
L
Sbjct: 505 L 505
>UniRef50_Q398R4 Cluster: Betaine-aldehyde dehydrogenase; n=11;
Burkholderia cepacia complex|Rep: Betaine-aldehyde
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 500
Score = 343 bits (842), Expect = 8e-93
Identities = 186/480 (38%), Positives = 265/480 (55%), Gaps = 11/480 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFID E A D + P G +A VA F W
Sbjct: 23 LFIDGEMQPAHAAARLDVYDPATGERLATVADADERDVDRAVASAKHAFDTRV-WSGLRP 81
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQG 128
+ R ++L K ADLIERD E LA+LE+ + G I G + VRY+ A KI G
Sbjct: 82 ADRERILLKLADLIERDAETLAQLETLNQGKSIHVSRAIEVGASVEYVRYMAGWATKITG 141
Query: 129 DTI------PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
T+ P +YT K+PVGV I+PWN P+++ + K++ ALAAGCT+V+KP+
Sbjct: 142 QTLDVSIPFPPGARYTAYTRKEPVGVVAAIVPWNFPLMIAVWKLIPALAAGCTIVLKPSP 201
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
+TPLT EAG+P GV N+V G G G AL HP +AKISFTGS GKL+
Sbjct: 202 ETPLTALRLAELALEAGVPPGVFNVVTG-GRVCGAALASHPSIAKISFTGSTATGKLVG- 259
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AA N+ R +LELGGK+P+++++D D+ A+ +G FF+QGQ+C AASR+YV +
Sbjct: 260 AAAVQNMTRFSLELGGKNPIVMLDDIDVAQALDGVAAGAFFNQGQVCAAASRIYVHRSKF 319
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+ G A+++++G D + P + +KV+ IE ++ G LAGG
Sbjct: 320 AQLADGLAGVAQSMKLGAGLDTTAQINPLVSAHHRDKVVQHIEGARRAGLTFLAGGTPAD 379
Query: 363 TA-GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GYY++P V AD + D I ++E+FGPV ++ FD + + AN + YGLAA I++
Sbjct: 380 DLPGYYVKPAVIADPHPDSAIVRDEVFGPVIVVVPFDDAADAVRLANASPYGLAASIWSN 439
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L + +EAGTVWVN ++ + PFGG+K SGIGRE G A+E + E K+V I+
Sbjct: 440 DLKRVMNLVPQIEAGTVWVNCHIPLDPSMPFGGYKQSGIGREFGQYAIEGFTETKSVCIA 499
>UniRef50_Q0S9W8 Cluster: Aminomuconate-semialdehyde dehydrogenase;
n=3; Corynebacterineae|Rep: Aminomuconate-semialdehyde
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 492
Score = 342 bits (841), Expect = 1e-92
Identities = 185/487 (37%), Positives = 267/487 (54%), Gaps = 9/487 (1%)
Query: 2 VPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRN 61
VP + + I +W A DG TF+T PHDGS++A V +G F +
Sbjct: 7 VPGVTEVRHLIGGDWAAASDGATFETRDPHDGSLLATVPRGTADDGEAAITAARTAFD-D 65
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLG 120
W +R K+L+ AD ++ E LA +E+ D G L + + ++R+
Sbjct: 66 GPWPRMSPKERAKILHAVADKVDEHREELALIETRDGGKSINQSLHAEIPRVAHNLRFFA 125
Query: 121 SLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
+ P DGD SY L P GV I PWN P+++ K+ ALA G T V+KP
Sbjct: 126 DYVSMAANEAYP-DGDLLSYVLYPPAGVVSAISPWNAPLMLATWKIAPALAFGNTTVLKP 184
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVA-LTHHPDVAKISFTGSLEVGKL 239
A QTPLT EAG+P+GV+N+V GFG +A LT P V +I+FTGS G
Sbjct: 185 APQTPLTAHRFAQLALEAGLPEGVLNVVHGFGGEAVAGPLTADPRVDRITFTGSSATGVR 244
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I +AA N+ V+ E+GGKS I+ DADL++A+P + +F GQ+C++ SRL VQ+
Sbjct: 245 ILQAAAVNHTP-VSAEMGGKSANIVFGDADLDVAVPMSIRAIFGGNGQVCLSGSRLLVQN 303
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
I +F+ E AK + VG+P D S GP I++ + KV G +E ++EG ++ GG
Sbjct: 304 SIMGEFLDRFTEEAKKLTVGDPKDPSNFLGPLIEQRHLEKVHGYVELAQEEGGKVVTGGS 363
Query: 360 RIG----TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLA 415
R+ G+Y PTV + +D A+EEIFGPV+++L FDT +E + AN++ YGLA
Sbjct: 364 RLTDDARAKGFYYPPTVITGLTNDSRTAREEIFGPVETVLGFDTEDEALRIANDSPYGLA 423
Query: 416 AGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEE 475
+FT NLN A + + +AGTVW+N + + PFGG SG+GRE G + E + E
Sbjct: 424 GILFTDNLNRAHRMAARWKAGTVWINTFFERDLRLPFGGEGSSGLGREGGQYSREFFTEP 483
Query: 476 KTVIISL 482
+ V I L
Sbjct: 484 RAVTIRL 490
>UniRef50_Q9AH09 Cluster: Putative aldehyde dehydrogenase; n=1;
Rhodococcus erythropolis|Rep: Putative aldehyde
dehydrogenase - Rhodococcus erythropolis
Length = 484
Score = 340 bits (835), Expect = 6e-92
Identities = 181/474 (38%), Positives = 272/474 (57%), Gaps = 9/474 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L I ++ + G TFD+ +P DGS +A VA+ + W+
Sbjct: 10 LVIGDQLTPSSTGATFDSINPADGSHLASVAEATAADVARAVEAAKAAART---WQRMRP 66
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
+QR +L++++A LIE LA+L+S D G + L I L + +++ Y L KI+G
Sbjct: 67 AQRTRLMFRYAALIEEHKTELAQLQSRDMGKPIRESLGIDLPIMIETLEYFAGLVTKIEG 126
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T P G +YTL++P+GV G I PWN P + + K+ ALA G +V+KPA+ PL
Sbjct: 127 RTTPAPGRFLNYTLREPIGVVGAITPWNFPAVQAVWKIAPALAMGNAIVLKPAQLAPLVP 186
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
EAG+P G+VN++PG G AG AL HP V K++FTGS EVG+ I + A +
Sbjct: 187 VALGELALEAGLPPGLVNVLPGRGSVAGNALVQHPSVGKVTFTGSTEVGQQIGRMA-ADR 245
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
L +LELGGKS L+ D+ ++ +QG+ C A SRL V+ IYD+ V+
Sbjct: 246 LITASLELGGKSALVAFGDSSPKAVAAVVFQAMYSNQGETCTAPSRLLVERPIYDEVVEL 305
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---- 364
+A RVG+P D T GP I V + +G +EGA L++GG++ T
Sbjct: 306 VQARVEAARVGDPLDPDTEIGPLISAEQRESVHSYVVSGTEEGATLISGGDQSPTGAPEQ 365
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G+Y +PT+F+ V DM IA+EEIFGPV S+L F+ EE I AN+T +GLAAG+FT ++
Sbjct: 366 GFYYRPTLFSGVTADMRIAREEIFGPVLSVLPFEGEEEAITLANDTVFGLAAGVFTRDVG 425
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
AL+F++ ++AG VW+N++ + +P+ GF SG G + G A+E++ +EK++
Sbjct: 426 RALRFAQTLDAGNVWINSWGVLNPASPYRGFGQSGYGSDLGQAAIESFTKEKSI 479
>UniRef50_Q5UWQ5 Cluster: Aldehyde dehydrogenase; n=1; Haloarcula
marismortui|Rep: Aldehyde dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 506
Score = 340 bits (835), Expect = 6e-92
Identities = 178/478 (37%), Positives = 270/478 (56%), Gaps = 9/478 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K F+D EW+ + +TF + P G + V +G +++ W
Sbjct: 30 KHFVDGEWITGRGDDTFQSIDPTTGESLVGVYEGTKEEVNRAVDAAWEAYEQR--WSETT 87
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
++R +LL AD +E E A +E DNG + D RY A I+G
Sbjct: 88 PAERQQLLLTMADRLEARAEDFALIEVLDNGKPITEAREDIELAVDHFRYFAGAARNIEG 147
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T+P + T ++P GV G ++PWN P+L+ K+ ALAAG TVV+KPAEQTP++
Sbjct: 148 KTVPHK-ELHIQTRREPYGVVGQVVPWNFPLLLATWKLAPALAAGNTVVLKPAEQTPISL 206
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+ +P GVVN+V GFG + G L H V K++FTGS EVG+ + KAA N
Sbjct: 207 LTYMREIADV-LPDGVVNVVTGFGPETGAPLVSHERVPKVAFTGSTEVGQGVMKAAA-NT 264
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+ +TLELGGKSPLI+ DAD A A +FF+ G+ C A +RL++ I D+FV
Sbjct: 265 ISDITLELGGKSPLIVAPDADPAEAADIAVDAMFFNGGECCSAGTRLFIHESIADEFVDA 324
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----ERIGTA 364
++ +++G+P +EST GPQ+ + + K L I + A++L GG E I
Sbjct: 325 FLDAVGKLQMGDPLEESTDIGPQVSRAEVEKTLHYIGLARDSDASILRGGGTVEEGILAE 384
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G +++PTV ADV D T+A +EIFGPV+ +L++D +E++ RANN +YGLAAG+ T +L+
Sbjct: 385 GCFVEPTVIADVGADSTVATQEIFGPVEIMLEWDGYDEMVARANNVDYGLAAGVVTDDLS 444
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + ++ + AG +WVN + + PFGG+K SGIGRE ++ + Y + K++ ++L
Sbjct: 445 FAHRIAEDIMAGNIWVNTFNRLPAGQPFGGYKQSGIGREGAMETLREYTQTKSITMNL 502
>UniRef50_Q39PC1 Cluster: Aldehyde dehydrogenase; n=70;
Bacteria|Rep: Aldehyde dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 501
Score = 338 bits (831), Expect = 2e-91
Identities = 185/468 (39%), Positives = 267/468 (57%), Gaps = 4/468 (0%)
Query: 17 VDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLL 76
V A+ G TF +P +VIA+VA F+ + W ++R ++L
Sbjct: 34 VPARSGRTFAAINPATEAVIAEVASCDAPDVDDAVRAARHAFESGA-WSRCAPAERKRVL 92
Query: 77 YKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDG 135
+ +LI LA L+S + G + I + + G DK+ G+ TD
Sbjct: 93 CRLGELIASHGAELALLDSLNMGKRVADAFSIDVPAAGGLFSWYGEAVDKLHGEVASTDP 152
Query: 136 DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX 195
+ + ++P+GV G ++PWN P+ M KV ALAAG +VV+KPAEQ+PL+
Sbjct: 153 GNLAVVTREPLGVVGAVVPWNFPLDMVAWKVAPALAAGNSVVLKPAEQSPLSALRLAELA 212
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
EAG+P GV+N+VPG+GE AG AL HPDV ++FTGS VGK + A +N+K+V LE
Sbjct: 213 LEAGLPPGVLNVVPGYGETAGRALGLHPDVDVLAFTGSTAVGKKFLEYAAQSNMKQVWLE 272
Query: 256 LGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAK 314
GGKSP ++ +D DL+LA A G+FF+QG++C A SRL VQ I+D FV + +A
Sbjct: 273 CGGKSPNLVFDDTDDLDLAARKACFGIFFNQGEVCSANSRLLVQRSIHDAFVDRLIAHAA 332
Query: 315 AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-ERIGTAGYYIQPTVF 373
A G+P D S+ G +DE +V I G+ + GG R+ GY+I+PT+F
Sbjct: 333 AFMPGDPLDPSSGMGAIVDEQQHRRVREWIARGRDSATLAIGGGAPRVDGKGYFIEPTIF 392
Query: 374 ADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHV 433
DV D IA+EEIFGPV S++ FDT +E + AN++ YGLAA ++T +L+ A + S +
Sbjct: 393 IDVKHDDAIAREEIFGPVLSVMAFDTEDEAVRLANDSIYGLAASLWTGSLSRAHRVSGRL 452
Query: 434 EAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
AGTV VN ++ Q PFGGF+ SG GR+ + A++ Y KT IS
Sbjct: 453 RAGTVSVNTVDALSAQTPFGGFRQSGFGRDLSLHAIDKYTGLKTTWIS 500
>UniRef50_Q1IRN9 Cluster: Aldehyde dehydrogenase; n=15; cellular
organisms|Rep: Aldehyde dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 505
Score = 338 bits (831), Expect = 2e-91
Identities = 181/479 (37%), Positives = 276/479 (57%), Gaps = 10/479 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K ID EWV++K G+TF+ +P D + + Q + +WRL
Sbjct: 15 KNLIDGEWVESKSGQTFENLNPADTREVVGIF--QRSGKEDVEHAIDAASEAYKKWRLVP 72
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A +R +LL+K A ++E+ E ++ + + G V K + D+ Y ++ G
Sbjct: 73 APRRAELLFKAAAILEQRKEKYSQEMTREMGKVIKETRGDVQEAIDAGYYNAGEGRRMFG 132
Query: 129 DTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
T P++ + F+ ++QP+GVC +I PWN P+ + K+ AL G T V+KPA+ TPL+
Sbjct: 133 PTTPSELPNKFAMAVRQPLGVCAMITPWNFPMAIPSWKLFPALVCGNTAVIKPAQDTPLS 192
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+AG+PKGV+NIV G+G + G +T HP+V +S TGS VG+++ +AA
Sbjct: 193 TFNFVQALNDAGVPKGVINIVTGYGGEVGTPMTEHPEVKAVSLTGSTAVGRIVGQAA-AK 251
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
+ K +LELGGK+P+I+++DA+L+LA+ A G F GQ C A SR+ +Q GIY KF
Sbjct: 252 SFKHCSLELGGKNPMIVLDDANLDLALEGALWGSFGTTGQRCTATSRIILQKGIYKKFAD 311
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--- 364
V A+ ++VGN DE+ GP ++E+ MN L IE GK EGA L GG R+
Sbjct: 312 ELVARARKLKVGNGLDETVDMGPAVNENQMNTDLKYIEIGKGEGAKLAHGGHRLDKGDYA 371
Query: 365 -GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G++++PT+F DVN M IA+EEIFGPV +++ D L+E I+ AN YGL++ I+T ++
Sbjct: 372 HGWFLEPTIFTDVNHKMRIAQEEIFGPVVALIPCDDLDEAIEIANGIEYGLSSAIYTRDV 431
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAH-QAPFGGFKDSGIG-RENGIKAVEAYLEEKTVII 480
N + + + + AG +VN A PFGG K +G G RE GI A++ Y E K + +
Sbjct: 432 NKSFRAMRDLHAGITYVNAPTIGAEVHMPFGGVKATGNGHREGGIGALDFYTEWKAIYV 490
>UniRef50_A6VY68 Cluster: Aldehyde dehydrogenase; n=36; cellular
organisms|Rep: Aldehyde dehydrogenase - Marinomonas sp.
MWYL1
Length = 497
Score = 336 bits (826), Expect = 7e-91
Identities = 176/476 (36%), Positives = 259/476 (54%), Gaps = 5/476 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFID W D + T +P G A A + + EW
Sbjct: 11 KLFIDGVWTDGAKARSMATINPATGETWATFAMAEAEDVDRAVKAARQALSKK-EWGGLT 69
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+QRG LL+K ADL+E+ L ++E+ D+G + + RY LADKI+G
Sbjct: 70 PTQRGGLLHKLADLLEQHSAALGEIETTDSGKLAAETQSQAKYVASYYRYYAGLADKIEG 129
Query: 129 DTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
T+P D D +T +P+GV ++PWN + + K+ ALAAGCTV++K +E P+
Sbjct: 130 HTLPIDKPDMHVFTKPEPIGVVAAVVPWNAQMFLTATKLAPALAAGCTVIIKASEIAPIA 189
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
++AG P GVV+++ G E + LT HPD+ +++FTG E K + + N
Sbjct: 190 ILEFAKLIEKAGFPSGVVSVITGDAEGCAIPLTSHPDIDRLAFTGGPETAKHVVRNTA-N 248
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
N +LELGGKSP+++ +DA++ A +G F GQ CVA SR+YVQ IY K +
Sbjct: 249 NFAVTSLELGGKSPILVFDDANIESAANGIIAGNFGASGQSCVAGSRVYVQRDIYPKILA 308
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG-- 365
+E AI VGNP D S+ GP + ++ + +E K++G +LAGG R+ G
Sbjct: 309 SLLEKTAAIVVGNPLDASSHIGPLCTLAQIDGIERALEKAKEQGGKILAGGIRLEGLGSD 368
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
YY PT+ +D+ E+FGPV SI FDT EE + AN++ +GL +G+FT NL
Sbjct: 369 YYFAPTIVECPTNDIETLHVELFGPVLSIACFDTEEEAVALANDSEFGLGSGVFTENLAR 428
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
AL+ S+ +++G WVN Y ++ APFGG SG GRE GI+A++ Y+ +T IS
Sbjct: 429 ALRVSQQIQSGICWVNTYRAVSPVAPFGGVNQSGYGREAGIQAIQDYIRVRTTWIS 484
>UniRef50_A5V831 Cluster: Aldehyde dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Aldehyde dehydrogenase - Sphingomonas
wittichii RW1
Length = 498
Score = 335 bits (824), Expect = 1e-90
Identities = 188/484 (38%), Positives = 268/484 (55%), Gaps = 17/484 (3%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
ID + A +G D+ P G V A++ G+ F+ WR A+Q
Sbjct: 18 IDGQSRPAANGGWIDSIDPATGQVWAQIPDGRADDIDAAVAAAKRAFR--GPWRQMAAAQ 75
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQGDT 130
R LL K A+L+ E LA +E+ DNG + + + I Y ADKI G+T
Sbjct: 76 RAALLRKVAELVGPRLEELAVIETRDNGKIITDTRAGDIPAIAQMFHYWAGAADKIHGET 135
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
I S +Y ++P+GV G+I+PWN P +F KV ALAAG TVVVKPAE +
Sbjct: 136 IQVSPASVNYVQREPIGVVGIIVPWNSPGSVFAAKVGAALAAGNTVVVKPAETASCSILV 195
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
++AG P GVVN+V G G +AG A+ HPDV KISFTGS + I + + +K
Sbjct: 196 LAELFEQAGFPPGVVNVVAGLGAEAGDAIAGHPDVGKISFTGSTLTARAITRRSA-EAIK 254
Query: 251 RVTLELGGKSPLIIMNDADLNLA-IPYAGSGVFFHQ-GQICVAASRLYVQSGIYDKFVKG 308
++ ELGGKS I+ DADL+ A I G+F GQ C+A SR+ VQ IYD+ +
Sbjct: 255 PLSFELGGKSANIVFADADLDAAAIGVTTMGIFNGAAGQSCIAGSRILVQRPIYDEMIAR 314
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---- 364
V+ IR+G+P D ++ GP + KV ++ G++EG L GG R G A
Sbjct: 315 MVKIITGIRLGDPMDAASQMGPIALDRQFEKVKSYLDLGRQEGGEALCGG-RAGEAVFGA 373
Query: 365 ------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
GY++QPT+FA +++ +EEIFGPV +L FD EE + AN++NYGLA G+
Sbjct: 374 GSPHAGGYFVQPTLFAGLDNQARTVREEIFGPVACVLPFDDAEEAVAIANDSNYGLACGL 433
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+T +L A + + +EAG VWVN Y + PFGG+KDSG GR++G++++ Y + K+V
Sbjct: 434 WTNDLKRAHRMAAAIEAGAVWVNTYRRLHWAVPFGGYKDSGYGRDSGMESLRGYQQTKSV 493
Query: 479 IISL 482
+ L
Sbjct: 494 WVDL 497
>UniRef50_UPI000023F6D5 Cluster: hypothetical protein FG11034.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG11034.1 - Gibberella zeae PH-1
Length = 926
Score = 333 bits (819), Expect = 5e-90
Identities = 189/482 (39%), Positives = 265/482 (54%), Gaps = 13/482 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAK---VAKGQXXXXXXXXXXXXXXFQRNSEW 64
TKLFI+NE+VDAK + +P DGS+++ VA Q W
Sbjct: 450 TKLFINNEYVDAKSDKRISVHNPIDGSLVSSDVHVAGPQDVDDAVEAAQAAYA----GPW 505
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
+ A+QR + L KFADL++ + LA+LE+ G +RI S + RY D
Sbjct: 506 KRFTAAQRSECLVKFADLVDSKEKELAELETIAMGQPTSIAVRITSMMSSLFRYYAGWTD 565
Query: 125 KIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
KI G+ +P +G + P GV I WN + KV A+AAG T+V K +E++
Sbjct: 566 KIHGEQLPPEGGVYKIISHHPYGVVAGISAWNGSAIQLGLKVAPAVAAGNTIVYKMSEKS 625
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
PL KEAG P GV+NI+ G GE G L H + ISFTGS G+ I +AA
Sbjct: 626 PLGMLQLGYLVKEAGFPPGVINILNGAGE-TGSLLASHMKIRMISFTGSGFTGRKISEAA 684
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+NLK+V LELGGKSP+++ NDA+ AI + + F+ GQ+C A SR+YVQ I
Sbjct: 685 AKSNLKKVALELGGKSPVLVFNDANTEKAIDFCTNMFLFNSGQVCAAPSRVYVQRDIATS 744
Query: 305 FVKG-AVEYAKAIR--VGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
F++ Y +A G+P D ST GP D + +V+G I++G KE A L GG R+
Sbjct: 745 FIETLKTRYTQAATGLGGDPKDPSTFMGPLADGAQYERVMGFIDSGNKE-AELAVGGHRV 803
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G GY++ PT+F + D I KEEIFGPV +++ FDT EE + AN+T YGLAA ++T
Sbjct: 804 GDQGYFVAPTIFVNPKSDARILKEEIFGPVLTVVTFDTEEEALKLANDTEYGLAAYVWTE 863
Query: 422 NLNNALQFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+L+ L+ S +EAG V +N L GGFK SG G E+G + + YL+ K +I
Sbjct: 864 SLSRGLRMSDQLEAGVVGINGGSLGAIPMMSVGGFKQSGTGSESGYEGIREYLQSKATLI 923
Query: 481 SL 482
++
Sbjct: 924 AM 925
>UniRef50_Q48AP9 Cluster: Betaine aldehyde dehydrogenase; n=1;
Colwellia psychrerythraea 34H|Rep: Betaine aldehyde
dehydrogenase - Colwellia psychrerythraea (strain 34H /
ATCC BAA-681) (Vibriopsychroerythus)
Length = 491
Score = 333 bits (818), Expect = 7e-90
Identities = 178/477 (37%), Positives = 260/477 (54%), Gaps = 10/477 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K +I+ WV ETF +P +VIA++ G F + W
Sbjct: 4 KHYINGTWVSPATSETFSVINPATEAVIAEIPAGNSVDIDAAVKAARTAFDQGP-WPRLS 62
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
++R L K A +I R + LAKLE DNG Y + + + LA+++
Sbjct: 63 GAERAVYLRKIAAIIIRRLDELAKLEVLDNGKPYPEAKWDIEDTAATFEFYAGLAEQLDN 122
Query: 129 DT-----IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ +P G S S +K+P+GV G I+PWN P+LM KV ALAAGC++++KP+E
Sbjct: 123 TSEQVIELPEPGFS-SKAIKEPLGVAGAIIPWNFPMLMAAWKVAPALAAGCSIILKPSEI 181
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT EA +P GV+NIV G G+DAG AL HPDV K++FTGS+ G I A
Sbjct: 182 TPLTALALAEIADEAKLPAGVLNIVTGLGKDAGQALVEHPDVDKLAFTGSIPTGSKIM-A 240
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
++K ++LELGGKSP +I D+D+ A+ + G+F++QGQ+C A SR+ V IY
Sbjct: 241 TAARDIKNISLELGGKSPFVIFEDSDIEKAVEWIMFGIFWNQGQVCSATSRVLVAKEIYP 300
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG- 362
++ VE K I +G + + GP ++ KVL IE G +GA + GG+R
Sbjct: 301 ALLERLVEETKKITIGPGDQDGVLLGPLVNSDQYKKVLAAIERGVSDGATIATGGQRPPG 360
Query: 363 -TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GYY++PT+ D++++ + EEIFGPV I F + E I AN++ +GLAA + +
Sbjct: 361 LDVGYYLEPTILTDIDENSWVWNEEIFGPVVCIKPFQSESEAIRLANDSRFGLAAAVMSK 420
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ + + S+ AG VWVN +AP+GG+K SGIGRE G + YLE K +
Sbjct: 421 DEDRCDRVSRAFRAGIVWVNCSQPTFVEAPWGGYKQSGIGRELGQWGLNNYLETKQI 477
>UniRef50_Q8TIR3 Cluster: Aldehyde dehydrogenase (NAD(P)+); n=7;
cellular organisms|Rep: Aldehyde dehydrogenase (NAD(P)+)
- Methanosarcina acetivorans
Length = 479
Score = 333 bits (818), Expect = 7e-90
Identities = 170/479 (35%), Positives = 270/479 (56%), Gaps = 9/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K+ I+ + V+A GE F +P G +I +V +G F + W A
Sbjct: 5 KMQINGKAVEACGGEVFGIKNPATGELIEQVPRGTEEDVAVAVEAASSAF---TGWASAS 61
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
QRG++LY+ A+++ + + LA L + + G + G + Y L+ +G
Sbjct: 62 PQQRGEVLYRAAEIVRQRKDELASLLTQEQGKPIVEARNEIEGFAHVLEYYCGLSGSQRG 121
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
D IP G+ +++T+K+P+GVC I+PWN+P L+ K+ L +G T+V+KPA TPLT
Sbjct: 122 DFIPVPGNGYAFTVKKPLGVCAAIIPWNMPALIMGWKIAPVLISGNTLVLKPASNTPLTN 181
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
EAG+P GV+N+V G GE G +L P+V KISFTG GK + + A
Sbjct: 182 LTLASIFVEAGLPAGVLNVVTGPGETVGESLVRSPEVRKISFTGEARTGKRVAELAAC-G 240
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+KR+TLELGG P+++ +DADL A A G F++ GQ C A RLYV + ++F+K
Sbjct: 241 MKRITLELGGSDPMLVCDDADLESAAAGALRGRFYNCGQTCTAVKRLYVFESVAEEFIKK 300
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGL-IETGKKEGANLLAGGE----RIGT 363
K++R+GN D++ GP + + + L E +K+ ++ GG+ +
Sbjct: 301 LETGIKSLRLGNGMDKNISMGPLNNRTQWEYIKELAAEIEEKDAGRIITGGKVPEFKDSE 360
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GY+ +PT+ +DV D + KEE+FGP+ ++ L+E I AN+T YGL A I+T N+
Sbjct: 361 KGYFFEPTLVSDVPGDSRLLKEEVFGPLLPVVTVKNLDEAIVGANSTCYGLGASIWTKNI 420
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ A + + + AG +W+N +L +A + PFGG K+SG GRENG +++ YLE KT+++ +
Sbjct: 421 DRARKGCEQLNAGIIWINQHLKVAPEVPFGGVKESGFGRENGPESLSEYLETKTIMLKI 479
>UniRef50_Q0SBJ9 Cluster: Aldehyde dehydrogenase; n=2;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 493
Score = 332 bits (817), Expect = 9e-90
Identities = 178/482 (36%), Positives = 265/482 (54%), Gaps = 4/482 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I +LFID +W +A GE F+ P G + VA+ F +
Sbjct: 13 PQIGPRQLFIDGQWREAGAGERFEIVDPSTGKPVTTVAEADADDLDSAVRAARTAFD-DG 71
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
W +R ++L + A L+ + + +ES D G C + + + Y +
Sbjct: 72 RWSGLPGRERARILLRVAALVRERADEIVAVESVDVGKPVSLCRPVDVMTTAEQYEYCAA 131
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
LA G T D+ +YT ++P+GV G I P+N P+++ +K+ ALAAG TVV KPA
Sbjct: 132 LAQTAGGSNRETPLDAHAYTRREPLGVLGAITPFNFPLILSTSKIAPALAAGNTVVHKPA 191
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E TPL+ EAG+P GVVN+V G G G AL H + KI+FTGS VG+
Sbjct: 192 EDTPLSALLMAEILTEAGVPAGVVNVVTGKGSTVGEALLQHKGIDKIAFTGSTVVGRHAA 251
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AG NL VT+ELGG + I+ DAD++ AI G F+ GQ C+ RL V
Sbjct: 252 SVAG-ENLTPVTMELGGNAAHIVFEDADVDKAIGAIIKGFVFNTGQFCMGGPRLLVARPH 310
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y+ + + + VG+PFD +TV GP + + KV ++ + +G ++AGGER+
Sbjct: 311 YETVLGILGQAVPGVPVGDPFDPATVVGPMAGDKHVRKVEEYVQIARSDGGRIVAGGERL 370
Query: 362 GTAG-YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G YY +PTV AD+ + + ++EIFGPV ++ FDT +E I AN+T YGLA+G+ T
Sbjct: 371 DLGGGYYYKPTVIADLPNTSRVVQDEIFGPVLTVQPFDTEDEAIALANSTEYGLASGLQT 430
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+N+ A + + ++AG VWVN++ + PFGG K+SG GRE G +A+E+Y + K+V+I
Sbjct: 431 SNVARAHRVAARLQAGIVWVNDWAMLDPAVPFGGVKNSGFGREYGPEALESYSKVKSVVI 490
Query: 481 SL 482
SL
Sbjct: 491 SL 492
>UniRef50_A6UK36 Cluster: Aldehyde dehydrogenase; n=2;
Sinorhizobium|Rep: Aldehyde dehydrogenase -
Sinorhizobium medicae WSM419
Length = 504
Score = 332 bits (816), Expect = 1e-89
Identities = 182/477 (38%), Positives = 259/477 (54%), Gaps = 5/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSP-HDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
++ +D + VDA G T D SP H G V+ + F W
Sbjct: 22 RMLVDGKSVDAVSGRTIDRVSPGHLGVVVGTWPEASPEDVRLAIAAARRAFD-TGPWPRM 80
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
++R +L++K ADLI E LA +ES + G + D Y A ++
Sbjct: 81 SGAERSRLMFKVADLILARQEELALIESLEVGKPIAQARGEIGFCADLWSYAAGQARALE 140
Query: 128 GDTIPTDGDS-FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G T GD L++PVGV G+I PWN P ++ +V A+ AGCTVV+KP+E T
Sbjct: 141 GQTHNNIGDDRLGLVLREPVGVVGIITPWNFPFIIASERVPWAIGAGCTVVLKPSEFTSG 200
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +EAGIP GV N+V G+G+ AG L P+V ++FTGS+ VG + + A
Sbjct: 201 TSIRMAELAREAGIPDGVFNVVTGYGDPAGQVLAEDPEVDMVAFTGSVRVGTKLGEIAA- 259
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
++KRV LELGGK P I+ DADL+ A GV+ + GQ C++ SRL VQ GI D +
Sbjct: 260 RSVKRVGLELGGKGPQIVFADADLDAAADGIAYGVYHNAGQCCISGSRLLVQEGIRDALM 319
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT-AG 365
+ ++ ++ + G+P +E T G I E+ KV + G GA LL GGER+G AG
Sbjct: 320 ERLLDISRKVTFGDPLNERTKIGAMISEAHAEKVHSYVTAGIASGAELLLGGERVGREAG 379
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y PTVF+ V DM+IA+EEIFGPV S L F T + + AN T +GL+A +++TNL
Sbjct: 380 LYYAPTVFSGVTPDMSIAREEIFGPVLSTLTFKTADHAVALANATEFGLSASVWSTNLET 439
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
ALQ + + AG W+N+ + + P GG+K SG+GRE G + Y + K V ++L
Sbjct: 440 ALQSIRRIRAGRCWINSVIDGTPELPIGGYKKSGLGRELGRYGFDEYSQFKGVHVTL 496
>UniRef50_A0KE30 Cluster: Aldehyde dehydrogenase; n=6; cellular
organisms|Rep: Aldehyde dehydrogenase - Burkholderia
cenocepacia (strain HI2424)
Length = 511
Score = 332 bits (816), Expect = 1e-89
Identities = 181/470 (38%), Positives = 266/470 (56%), Gaps = 7/470 (1%)
Query: 18 DAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLY 77
DA G TF+ +P G +A V ++ W A R + L
Sbjct: 44 DAAAGRTFEKLAPATGDYVAAVPASTAEDVDRAVRAAHAALHDDA-WARAGGPARARWLL 102
Query: 78 KFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDG- 135
+ ADL+ERD L +L + + G + L D++RY ADK++G TIPTDG
Sbjct: 103 RLADLVERDGNALTELLAVEQGRPLAEMRMMDLPMCIDTLRYFAGWADKLEGRTIPTDGF 162
Query: 136 ---DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXX 192
+ SYT + PVGV G I+PWN P+++ + K+ ALAAGC VVVKP+E TPL
Sbjct: 163 MGRPTLSYTRRAPVGVAGQIIPWNAPLMIAVWKLAPALAAGCPVVVKPSEDTPLAITRLG 222
Query: 193 XXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRV 252
EAG+P GVVNIV G G + G AL HP V KISFTGS EVG+ I A KRV
Sbjct: 223 ELVCEAGLPAGVVNIVHGIGAEVGAALVAHPLVNKISFTGSTEVGRAIAGVAA-KTFKRV 281
Query: 253 TLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEY 312
TLELGGK+ I+ DADL+ AIP +G+F +QGQ C A SR+ I + +
Sbjct: 282 TLELGGKAAQIVFADADLDRAIPSLMAGMFANQGQTCAAGSRVLAHRSIAQALEERLADA 341
Query: 313 AKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTV 372
A+A+R+G P + G I+ + +V L++ EGA +LAG E++ G +++PT+
Sbjct: 342 ARAMRIGPPSEPGVQMGALINPRHLARVRTLVDGALAEGAVMLAGDEQVPPRGCFMRPTI 401
Query: 373 FADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKH 432
V+ M IA++E+FGPV ++ F+T ++ + AN+T +GL+A ++T ++ A + ++
Sbjct: 402 LGGVHPGMRIARDEVFGPVGMVMPFETEDDAVRIANDTPFGLSASVWTQDVGTAHRVAER 461
Query: 433 VEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ G V +N + + + P+GG K SGIGR+ A+++YLEEK V +L
Sbjct: 462 LDVGAVAINAWSPIDARLPWGGTKQSGIGRDLSKAALDSYLEEKIVTAAL 511
>UniRef50_Q47943 Cluster: L-sorbosone dehydrogenase, NAD(P)
dependent; n=3; Proteobacteria|Rep: L-sorbosone
dehydrogenase, NAD(P) dependent - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 498
Score = 332 bits (815), Expect = 2e-89
Identities = 183/477 (38%), Positives = 255/477 (53%), Gaps = 5/477 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID EW KD FD SP + ++ + F+ N W A+
Sbjct: 20 FIDGEWRAGKD--FFDRSSPAHDVPVTRIPRCTREDLDEAVAAARRAFE-NGSWAGLAAA 76
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R +L K A L+ + +A E +NG + A + GDT
Sbjct: 77 DRAAVLLKAAGLLRERRDDIAYWEVLENGKPISQAKGEIDHCIACFEMAAGAARMLHGDT 136
Query: 131 IPTDGDS-FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
G+ F L++P+GV GLI PWN P ++ + LA+GCT+VVKPAE T T
Sbjct: 137 FNNLGEGLFGMVLREPIGVVGLITPWNFPFMILCERAPFILASGCTLVVKPAEVTSATTL 196
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+AG+PKGV N+V G G G A+T H D+ +SFTGS VGK AA +NL
Sbjct: 197 LLAEILADAGLPKGVFNVVTGTGRTVGQAMTEHQDIDMLSFTGSTGVGKSCIHAAADSNL 256
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K++ LELGGK+P+++ D++L A G+ F+ GQ CV++SRL V+ + +KF +
Sbjct: 257 KKLGLELGGKNPIVVFADSNLEDAADAVAFGISFNTGQCCVSSSRLIVERSVAEKFERLV 316
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA-GYYI 368
V + IRVG+PFD T G E+ +L I GK EGA LL GG + G YI
Sbjct: 317 VPKMEKIRVGDPFDPETQIGAITTEAQNKTILDYIAKGKAEGAKLLCGGGIVDFGKGQYI 376
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
QPT+F DV M IA++EIFGPV + FDT++E I AN+T YGLAA +++ +++ AL
Sbjct: 377 QPTLFTDVKPSMGIARDEIFGPVLASFHFDTVDEAIAIANDTVYGLAASVWSKDIDKALA 436
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
++ V AG WVN ++ + P GGFK SG GRE G+ VE Y + K+V I K+
Sbjct: 437 VTRRVRAGRFWVNTIMSGGPETPLGGFKQSGWGREAGLYGVEEYTQIKSVHIETGKR 493
>UniRef50_A1G8I3 Cluster: Aldehyde dehydrogenase; n=2;
Salinispora|Rep: Aldehyde dehydrogenase - Salinispora
arenicola CNS205
Length = 536
Score = 332 bits (815), Expect = 2e-89
Identities = 187/486 (38%), Positives = 268/486 (55%), Gaps = 12/486 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L + W ++DG T+ P G + + A F W + A
Sbjct: 53 LLVAGAWRPSRDGGTWVHLHPATGEEVGEFAIADPADVDAAVRAARQAFDEGP-WPRSRA 111
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSG--IPDSVRYLGSLADKI 126
+R ++L + ADLI + L L++ DN + + ++S D + DK+
Sbjct: 112 RERIRVLRRAADLIREHSDELLALQALDNSVPLSFSGAYVMSAECAADVFDHHAGWIDKL 171
Query: 127 QGDTIPT--DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P GD +TL++P+GV ++PWN P+L+ K+ ALA+GCTVV+KP+E
Sbjct: 172 GGETLPPYQGGDHLVFTLREPIGVVAAVIPWNAPLLLAAQKLAPALASGCTVVLKPSEYA 231
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
EAG+P GV+N+V G GE G AL HP V KI+FTGS VG+ I AA
Sbjct: 232 TFAVLRLVQILDEAGVPPGVLNVVTGPGESTGEALITHPMVDKITFTGSRAVGRRILHAA 291
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYA-GSGVFFHQGQICVAASRLYVQSGIYD 303
+ + +V+LELGGKSP I+ DAD+ A G+ GQ+CVA SR VQ +YD
Sbjct: 292 -ADGITKVSLELGGKSPSIVFADADVYAAAAMTMGTVTVGLSGQVCVAHSRALVQREVYD 350
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG- 362
+FV A G+PFD T P I+ +++VLG + G+ EGA L+ GGER+G
Sbjct: 351 EFVSIATGATALACYGDPFDAETTASPLINGRQLDRVLGYVAQGQAEGARLVCGGERVGG 410
Query: 363 --TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
AG ++ P +FADV DMTIA+EEIFGPV + F +E I AN+T YGLAA ++T
Sbjct: 411 ELAAGNFVTPALFADVASDMTIAREEIFGPVLGVTPFTDEQEAIRLANDTEYGLAAMVWT 470
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++ A++ ++ V AGT+ VN Y H A FGGF SG+GRE G + EA+ E KTV++
Sbjct: 471 ADVKRAMRLTRAVRAGTIGVNGYQVEPH-AAFGGFGQSGLGREGGRGSAEAFTEVKTVLV 529
Query: 481 SLPKKL 486
++L
Sbjct: 530 PTTEEL 535
>UniRef50_Q1QBF6 Cluster: Aldehyde dehydrogenase; n=3;
Gammaproteobacteria|Rep: Aldehyde dehydrogenase -
Psychrobacter cryohalolentis (strain K5)
Length = 498
Score = 331 bits (813), Expect = 3e-89
Identities = 174/461 (37%), Positives = 261/461 (56%), Gaps = 8/461 (1%)
Query: 24 TFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLI 83
T D ++P D S+I ++A G F+ N EWR ++R ++ ++ L+
Sbjct: 36 TLDNYTPIDNSIIGQIASGNSDDVDTAVQVARDAFE-NGEWRRLAPAERKAIMQRWCALM 94
Query: 84 ERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTL 142
E LA L+ D G CL + ++ + ADK+ G PT + +
Sbjct: 95 HEHVEELAALDCVDAGKPITECLNTDIPATIETFEWYAEAADKVFGKVAPTGSAALGLIV 154
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
++P+GV G +LPWN P M+ KV ALA G +V+VKPAE T L+ EAG+P+
Sbjct: 155 QEPIGVVGAVLPWNFPAQMYAWKVAPALAMGNSVIVKPAELTSLSAYRLTELAYEAGVPR 214
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
+ +V G GE+ G AL H DV +SFTGS EVG+L + + +NLK + LE GGKSP
Sbjct: 215 EALQMVCGLGENVGAALGQHMDVDMVSFTGSTEVGRLFLQYSAQSNLKEIVLECGGKSPQ 274
Query: 263 IIMNDADL-NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNP 321
I+ +DA L + AI S F++ + C SRL V S ++ K +VG+P
Sbjct: 275 IVFDDAVLDDAAINDILSAAFWNMSENCSCGSRLLVHSSQKQALLEQLKNGLKGWKVGSP 334
Query: 322 FDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG---ERIGTAGYYIQPTVFADVND 378
+D T GP I+++ +KV ++T K+EGA ++AGG E +G +G+YI+PT+F V+
Sbjct: 335 YDPDTAIGPMIEKAHFDKVCHYLKTAKEEGATIVAGGNIREDLG-SGWYIEPTIFDHVSA 393
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
DMT+ KEE+FGP+ ++ F+T EE I AN TNYGLAA +T N+ A + + ++AGTV
Sbjct: 394 DMTLFKEEVFGPLLAVTSFETEEEAIKLANETNYGLAASFYTQNIKRAYRVASSIKAGTV 453
Query: 439 WVNNYLTMAHQAPFGGFKDSGI-GRENGIKAVEAYLEEKTV 478
+N + PFGG+K SG GR+NG++A+ Y + KT+
Sbjct: 454 SINGFSEGDITTPFGGYKQSGFGGRDNGLEALAQYAQTKTI 494
>UniRef50_Q89NG4 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|Rep:
Aldehyde dehydrogenase - Bradyrhizobium japonicum
Length = 509
Score = 330 bits (812), Expect = 4e-89
Identities = 175/475 (36%), Positives = 257/475 (54%), Gaps = 6/475 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID V+A +G D +P G VIA++ F+ + W D
Sbjct: 18 FIDGREVEAGNGAMLDVRNPATGDVIARIPNSTAEDIDRAMKSARAAFEGKA-WGGMDTR 76
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R +L+ K AD E + + L +LE+ +NG LS +PD RY +A +
Sbjct: 77 ARARLVNKLADAFEANLDSLYRLETLNNGRPVNETRAQLSRLPDFFRYFAGVALARRDSV 136
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
IP +G +YTL+ P+G+ P+N P+++ + LA GC VVKP+E TPLT
Sbjct: 137 IPVEGAYLNYTLRTPIGIVANCTPFNHPLMILCKSLAVVLATGCVTVVKPSEYTPLTTLK 196
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
EAG+P GV NIV G G+ AG L H D+ K+ TG E G++ AA
Sbjct: 197 LAQIFTEAGLPPGVFNIVLGHGQSAGKMLAEHGDIDKLVLTGGTEAGRIAGSAA-ARVFA 255
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
T+ELGGK+P+++ +D D++ A+ YA G F GQ CV ASR VQ+ IYD+FV+
Sbjct: 256 HQTMELGGKTPVMVFDDFDVDRAVNYAAFGAFIGAGQTCVCASRHIVQASIYDEFVEKLQ 315
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA----GY 366
+ IRVG+PFD ST GP I ++VL G ++GA L+ GG GY
Sbjct: 316 AKTRTIRVGDPFDASTQMGPVISARQRDRVLTYAGYGHEDGARLVTGGVAAKVPGHDNGY 375
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+++PTVFADV DM I +EE+FGP S+ F + + AN++ +GLAA I T ++ A
Sbjct: 376 FVEPTVFADVTSDMRIFQEEVFGPFTSVTPFKDEADALRLANDSPFGLAAAIRTRDVARA 435
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+ + V+AG VW+N++ + +P+GG DSGIGRE G ++ + K+V+++
Sbjct: 436 HRVAASVKAGIVWINDHHRLDPASPWGGVDDSGIGRECGTESFNDHFNTKSVMVA 490
>UniRef50_Q7Z1Q3 Cluster: Aldehyde dehydrogenase protein 12, isoform
a; n=3; Caenorhabditis|Rep: Aldehyde dehydrogenase
protein 12, isoform a - Caenorhabditis elegans
Length = 499
Score = 329 bits (809), Expect = 8e-89
Identities = 185/481 (38%), Positives = 265/481 (55%), Gaps = 13/481 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
F++ + + ETFD P G V+AK K S W A
Sbjct: 15 FLNGKRTTIESTETFDVIEPRIGQVVAKCPKATADIVDQYVKAAADA---QSAWGETTAL 71
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKI-QGD 129
RGK+L+K ADLI E +A E NG ++ D+ + G +A + QGD
Sbjct: 72 DRGKVLHKVADLIREHAEEIAIWEVKTNGKPIYEARCDIASSADTFDFFGGIATAVLQGD 131
Query: 130 TIPTDG---DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
++ G +YT ++P GV G I WN P + KV ALAAG VV KP+ P
Sbjct: 132 SLELPGGPSQRIAYTRREPYGVVGCIGAWNYPFQTCVWKVAPALAAGNAVVYKPSPFAPA 191
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ AG+PKGV N++ G ++AGVAL H VAK+SFTGS+ G+ +Q+ A T
Sbjct: 192 SPVLLGEILTAAGVPKGVYNVIQG-EQEAGVALCEHNLVAKVSFTGSVASGEAVQRQAAT 250
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N+K VTLELGGKS +II +D+D+ A+ A F +QGQ+C A+R++VQ GI F
Sbjct: 251 KNVKPVTLELGGKSEIIIFDDSDVKSAVASAMLANFLNQGQVCTNATRVFVQKGILASFT 310
Query: 307 KGAVEYAK-AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
+ V+ A ++VG+P E T G I+E + ++LG +E+ K+EG +L GG R+ G
Sbjct: 311 EAIVQEANDKLKVGDPLLEDTRVGANINEGHLQRILGYVESAKQEGGVVLRGGVRVHPTG 370
Query: 366 Y----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
Y +P + ++D+ +EEIFG V IL F+T EEVI RANNT YGLAAG+F+
Sbjct: 371 VEGGAYFEPAIITGLSDEARAVREEIFGAVMLILPFETEEEVIARANNTTYGLAAGVFSG 430
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
NL + + ++AGTV++N Y PFGGFK+SG GREN I + A+ + K + ++
Sbjct: 431 NLARGHRVAARLQAGTVFINTYNDTEVNVPFGGFKNSGHGRENCIDTLRAHTQTKAIYVN 490
Query: 482 L 482
+
Sbjct: 491 V 491
>UniRef50_Q396X6 Cluster: Aldehyde dehydrogenase; n=18; cellular
organisms|Rep: Aldehyde dehydrogenase - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 500
Score = 328 bits (806), Expect = 2e-88
Identities = 175/478 (36%), Positives = 270/478 (56%), Gaps = 10/478 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID + A G+TF T +P +V+A++ F+ + WR S
Sbjct: 24 FIDGAFRTASSGDTFATVNPATDAVLAQIGACNAADVDIAVANARQAFE-DGRWRKLAPS 82
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RYLGSLADKIQ 127
R +L KFADL+E+ LA +ES D+G + C I +P+++ R+ L DKI
Sbjct: 83 HRKAVLLKFADLLEQHAHELATMESLDSGKPIRECQTI--DVPETIHTIRWHAELIDKIY 140
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+T P G++ + +++P+GV GL+LPWN P+LM K+ +LAAGC++VVKPA++T LT
Sbjct: 141 DNTAPVGGNALALVVREPIGVVGLVLPWNFPLLMLAWKIGPSLAAGCSIVVKPAKETTLT 200
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
EAG+P GV N++PG G + G L H DV +SFTGS + G+ K A +
Sbjct: 201 ALRVAELAHEAGVPAGVFNVLPGGGREVGEPLGRHADVDMVSFTGSTDTGRKFLKYAAES 260
Query: 248 NLKRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
NLKR+ LE GGK+P +++ DA DL+ + +G F++ G+ C A+SRL V + I D +
Sbjct: 261 NLKRIVLECGGKNPAVVLPDAPDLDAVAQHIVNGAFWNMGENCSASSRLIVHADIKDDLL 320
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ + ++GNP D + G + ++ KV +E E ++ GG+ G G
Sbjct: 321 QRIGTQMREWKMGNPLDPAHRIGAMVSKAHFEKVRSYLEQAGAEHLHVAFGGQTDG--GI 378
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+++PTV V+ + +EEIFGPV S+ F + E I AN++ YGLAA ++T +LN A
Sbjct: 379 FVEPTVVDGVSPHSRLFREEIFGPVLSVTTFTDIAEAIALANDSVYGLAASVYTGSLNLA 438
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGI-GRENGIKAVEAYLEEKTVIISLP 483
++ S+ + AG V VN + PFGG+K+SG GR+ + A + Y E KT+ I +P
Sbjct: 439 IRLSREIRAGVVTVNCFGEGDVTTPFGGYKESGFGGRDKSVWAHDQYTEIKTIWIDVP 496
>UniRef50_P23240 Cluster: Aldehyde dehydrogenase; n=339;
Bacteria|Rep: Aldehyde dehydrogenase - Vibrio cholerae
Length = 506
Score = 328 bits (806), Expect = 2e-88
Identities = 192/482 (39%), Positives = 264/482 (54%), Gaps = 17/482 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I +W+ GE F SP +G V +VA+ + W A
Sbjct: 22 YIGGQWMKPHSGEYFSNTSPVNGLVFCRVARSSSQDVELALDAAHNALE---SWSTTSAV 78
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGD 129
+R +L + AD IE + E LA +ES+DNG + L L D RY + +G
Sbjct: 79 ERSNILLRIADRIESNLETLAIVESWDNGKPIRETLAADLPLTIDHFRYFAACIRSQEGA 138
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
D + +Y L +P+GV G I+PWN P+LM K+ ALAAGCTVV+KPAEQTP++
Sbjct: 139 ASELDSRTLTYHLPEPIGVVGQIIPWNFPLLMAAWKLAPALAAGCTVVLKPAEQTPVSIL 198
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+ IP GV+N+V GFG +AG AL + K++FTGS E+G I K A +NL
Sbjct: 199 FLMEIIGDL-IPAGVINVVNGFGSEAGNALATSQRIDKLAFTGSTEIGNHILKCAA-DNL 256
Query: 250 KRVTLELGGKSPLI----IMNDADLNLAIPYAGSGV-FFHQGQICVAASRLYVQSGIYDK 304
T+ELGGKSP I I + D L G+ + FF+QG++C SR+ V IY+K
Sbjct: 257 IPSTIELGGKSPNIYFPDIFSHEDQYLDKCIEGALLAFFNQGEVCTCPSRILVHESIYEK 316
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-----E 359
F+ +E I+ GNP D T G Q+ + +K+LG I+ GK EGA L+ GG E
Sbjct: 317 FIAKIIERVALIKQGNPLDTETQIGAQVSKEQYDKILGYIQIGKDEGAELIFGGHPNNQE 376
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
+ GYYI+PT+F N M I +EEIFGPV +I KF E + AN+T YGL AG++
Sbjct: 377 NYLSGGYYIKPTLFFGHNQ-MHIFQEEIFGPVIAITKFKDEIEALHLANDTVYGLGAGVW 435
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T ++N A + +K+++AG VWVN Y A FGG+K SGIGRE + Y K V+
Sbjct: 436 TRDINIAHRMAKNIKAGRVWVNCYHAYPAHAAFGGYKKSGIGRETHKLTLSHYQNIKNVL 495
Query: 480 IS 481
IS
Sbjct: 496 IS 497
>UniRef50_Q739I7 Cluster: Aldehyde dehydrogenase; n=3;
Bacillaceae|Rep: Aldehyde dehydrogenase - Bacillus
cereus (strain ATCC 10987)
Length = 489
Score = 326 bits (802), Expect = 6e-88
Identities = 186/485 (38%), Positives = 268/485 (55%), Gaps = 12/485 (2%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
++K KLFID ++VD+ GETFDTF+P +A +AK F ++
Sbjct: 11 KVKDAKLFIDGKYVDSVCGETFDTFNPATNRKLASIAKANEEDTKRAIDVAERTF-KSGI 69
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RYLG 120
W +R +L K +DLI + LA +E+ D G K IP S R+
Sbjct: 70 WSKMPVEERSNILCKMSDLIMERVDELAYIETLDVGKPIKESKGF--DIPRSAHNFRFFA 127
Query: 121 SLADKIQGDTIPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
+A I + D +F SY P GV LI+PWN+P + K ALA+G TVVVK
Sbjct: 128 EMAKYIVHEHY--DKHNFMSYAKYAPAGVTSLIIPWNLPFMQMTWKASAALASGNTVVVK 185
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
PA TPL+ +AG+P GV+NI+ G G G +T HP V +ISF G GK
Sbjct: 186 PASYTPLSAVMLGEIANDAGLPPGVLNIITGPGSTVGTKMTTHPAVRRISFVGESNTGKT 245
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I + A + NL V+LELGGKS I+ DADL+ A+ + ++ +QG+IC+A SRL VQ
Sbjct: 246 IMRNA-SENLIPVSLELGGKSANIVFEDADLDEAVQGSIEAIYRNQGEICLAGSRLLVQE 304
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
+Y++F++ V K I+VG+P E T G + +S + V +E G EGA L GG+
Sbjct: 305 SVYEQFLEKFVAAVKRIKVGDPLSEDTDMGALVSKSHLETVDRYVELGISEGAKLAYGGK 364
Query: 360 RIGTA--GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
R+ + G + +PT+ DV++ M +A+EEIFGPV ++ F T E+ I AN++ YGLA
Sbjct: 365 RVESLVEGNFYEPTILYDVDNSMRVAQEEIFGPVLVVIPFKTEEDAIRIANDSIYGLAGV 424
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
++T +L A + +++G +W+N + + PFGG K SGIGRE G + E Y E KT
Sbjct: 425 VWTNDLRRAQRVVSQIDSGLLWINCWYVRDLRTPFGGSKASGIGREGGRHSFEFYTEAKT 484
Query: 478 VIISL 482
V + L
Sbjct: 485 VTMKL 489
>UniRef50_Q5UWQ8 Cluster: Aldehyde dehydrogenase; n=4;
Halobacteriaceae|Rep: Aldehyde dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 532
Score = 326 bits (801), Expect = 8e-88
Identities = 170/480 (35%), Positives = 271/480 (56%), Gaps = 12/480 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I E+V +T +T P +V+ +V G F + W+ A
Sbjct: 56 YIGGEFVAGNSHKTIETRDPTTDAVLGEVPAGNAADIDDAVKAAQQAF--DGGWKDASPG 113
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + A +E + + LA LE D G + + + D + Y + A + G+T
Sbjct: 114 ERQRVLSEMAHAVEENRKTLATLEVLDTGKTITEAMGDMGLVIDHLTYYAAAARNVNGET 173
Query: 131 IPT----DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D + +T+K+P GV G I+PWN P+L+ + K ALAAG TVV+KP+E+TPL
Sbjct: 174 RQTNDLFDREKQVFTVKEPYGVVGAIVPWNFPLLIAIWKCGPALAAGNTVVLKPSEETPL 233
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ +P GV+N+V G+GEDAG L+ H DV KISFTGS EVGK I + +
Sbjct: 234 STLKLMELVDNT-VPDGVINVVTGYGEDAGAPLSTHEDVPKISFTGSTEVGKEIIRNSA- 291
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
++K+ TLELGGKSP+I+ DADL A+ A +FF++G+ C A SRL+V I ++F+
Sbjct: 292 EDIKKTTLELGGKSPVIVYPDADLEEAVEAAMMAIFFNKGECCAAGSRLFVHEDIEEQFL 351
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----ERIG 362
+ A + VG+P E T GP++ + + + +E ++ GA + GG +
Sbjct: 352 ETFTNAASGMTVGDPLLEETDMGPKVSDEQVQRTNEFVEAARESGATIRTGGSAPDDESL 411
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G + +PTV D++ D ++EIFGPV + ++V++ AN+ +YGLAAG+ + +
Sbjct: 412 AGGAFYEPTVIDDIDHDHPSVQKEIFGPVMETFSWSDEDDVVELANDVDYGLAAGVISGD 471
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ ALQ ++ +EAG VWVN+Y ++ PFGG+K SG GREN +A++ + + K + ++L
Sbjct: 472 VTKALQTARRLEAGVVWVNHYNDVSAGQPFGGYKQSGTGRENAAEAIDEFTQTKAINVNL 531
>UniRef50_Q6FBY4 Cluster: Putative aldehyde dehydrogenase; n=1;
Acinetobacter sp. ADP1|Rep: Putative aldehyde
dehydrogenase - Acinetobacter sp. (strain ADP1)
Length = 487
Score = 324 bits (795), Expect = 4e-87
Identities = 178/465 (38%), Positives = 262/465 (56%), Gaps = 8/465 (1%)
Query: 23 ETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADL 82
+TF +P D +IA + K ++ W QR L+ FAD
Sbjct: 25 QTFQDINPCDEILIAHIPKASVEDLNAIVAVAKQGLN-STAWHEVTPLQRENLIRCFADA 83
Query: 83 IERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDT--IPTDGDSF- 138
IE+D LA+LES D G + + + ++Y A KI G + SF
Sbjct: 84 IEKDSTRLAQLESIDAGKPISITQTVDIPAVVAWLKYYAGWASKIMGSAGELSNVAGSFH 143
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y+ +QPVGV I PWN P ++ + K+ ALAAGC +V+KPA TPLT +E
Sbjct: 144 AYSRRQPVGVVAAITPWNFPSVLSMWKIAPALAAGCCIVLKPASDTPLTALRLAEIAREI 203
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
G P+GV N+V G D G AL HPD+AK++FTGS + G+ I +A+ + KRVTLELGG
Sbjct: 204 GFPEGVFNVVTG-NSDIGHALATHPDIAKVAFTGSTQTGRSILQAS-IADFKRVTLELGG 261
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP+I+ DADL+ AIP G FF+ GQ+C A +RLYV IYD+ + + K +++
Sbjct: 262 KSPVILHKDADLDKAIPTIAMGCFFNTGQVCYAGTRLYVHHDIYDEVLARLAAFTKTLKI 321
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLL-AGGERIGTAGYYIQPTVFADVN 377
G+ D +T GP ++ + + + +++G L + G+Y++P + +V
Sbjct: 322 GSSDDPNTQLGPVVNARQQHSIQEFLNKAEQQGIESLDLSAMTLPEHGFYVRPAILKNVP 381
Query: 378 DDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGT 437
I KEE+FGPV + + +L+E I +N++ YGLAA ++T +L+ A Q S ++AGT
Sbjct: 382 AHAAIMKEEVFGPVLATAAYQSLDEAIQLSNDSIYGLAAHLWTQDLSIAHQVSAALDAGT 441
Query: 438 VWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
V+VN L PFGGFK SGIGRENG + ++AYLE K+VI++L
Sbjct: 442 VFVNCALLADPNFPFGGFKQSGIGRENGQEVLDAYLESKSVIMAL 486
>UniRef50_P80668 Cluster: Phenylacetaldehyde dehydrogenase; n=23;
Bacteria|Rep: Phenylacetaldehyde dehydrogenase -
Escherichia coli (strain K12)
Length = 499
Score = 323 bits (794), Expect = 6e-87
Identities = 175/478 (36%), Positives = 264/478 (55%), Gaps = 9/478 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L+ID A+ + F P G IA A F + W
Sbjct: 22 LYIDGRPGPAQSEKRLAIFDPATGQEIASTADANEADVDNAVMSAWRAFV-SRRWAGRLP 80
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQG 128
++R ++L +FADL+E+ E LA+LE+ + G G + +RY L KI G
Sbjct: 81 AERERILLRFADLVEQHSEELAQLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAG 140
Query: 129 DTI------PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
T+ P ++T K+PVGV I+PWN P+++ + KV+ ALAAGC++V+KP+E
Sbjct: 141 KTLDLSIPLPQGARYQAWTRKEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSE 200
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
TPLT EAGIP GV N+V G G G ALT HP VAKISFTGS GK I +
Sbjct: 201 TTPLTMLRVAELASEAGIPDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIAR 260
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A ++L RVTLELGGK+P I++ DAD I +G F +QGQ+C A+SR+Y+++ ++
Sbjct: 261 TAA-DHLTRVTLELGGKNPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLF 319
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D V G + K+++VG P + + +KV ++ + + A L+ G
Sbjct: 320 DTLVSGFEQAVKSLQVGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPA 379
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GYY+ PT+ + + + + +EE+FGPV ++++ EE + AN+T YGL A ++T N
Sbjct: 380 GEGYYVAPTLVVNPDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQN 439
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
L+ AL++S ++AGTVWVN++ + PFGG K SG GR+ G ++ + E K+V +
Sbjct: 440 LSQALEYSDRLQAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCV 497
>UniRef50_Q5KVH3 Cluster: 5-carboxy-2-hydroxymuconate semialdehyde
dehydrogenase; n=9; Bacteria|Rep:
5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase -
Geobacillus kaustophilus
Length = 503
Score = 322 bits (790), Expect = 2e-86
Identities = 176/475 (37%), Positives = 266/475 (56%), Gaps = 6/475 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I+ ++V+ G FD +P I ++A+G+ F + WR
Sbjct: 10 YINGQFVEGAAGAYFDNINPFTNGTINQIAEGRKEDIDAAVRAAKEAFD-HGPWRTMPVE 68
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD-KIQGD 129
+R + L++ ADLIE+ + +A LE+ D G+ + + ++ R+ + ++ G+
Sbjct: 69 RRLRYLFRIADLIEQYADDIAYLEALDTGIPISQAKKQAARAAENFRFYAEMVKTRLVGE 128
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+G +YT+ +PVGV GLI PWN P ++ KV ALA G TVV+KPAE +PLT
Sbjct: 129 AYHVNGQFLNYTVYKPVGVAGLITPWNTPFMLETWKVAPALATGNTVVLKPAEWSPLTAN 188
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG-KLIQKAAGTNN 248
EAG+P+GV N+V GFGE AG AL HPDV ISFTG G ++I+ +A T
Sbjct: 189 KLAEIIDEAGLPRGVFNVVHGFGETAGAALVAHPDVRLISFTGETTTGMEIIRNSAAT-- 246
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LK+ ++ELGGKSPLI+ DADL A+ A GVF G+ C A SRL ++ IYD+FV
Sbjct: 247 LKKTSMELGGKSPLIVFADADLERALDAAVWGVFSLNGERCTANSRLLLEQSIYDEFVAR 306
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-TAGYY 367
E I +G+P +T GP I + +V I+ K+EGA++ A G G +
Sbjct: 307 LKERVDRIVIGDPMAPATELGPLIHRAHWERVNRYIDIAKQEGADVYAPSVPTGLEKGNF 366
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+ PT+ ++ M +A+EEIFGPV +++ F EE I AN+ YGLAA ++T ++
Sbjct: 367 VPPTLLLGCHNGMRVAQEEIFGPVMAVMSFADEEEAIRLANDVKYGLAAYVWTNDMKRGH 426
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ ++ +E+G WVN+ + PFGG K SGIGRE G + + Y E + V +++
Sbjct: 427 RVAQAIESGMAWVNSPNVRDLRIPFGGTKYSGIGREGGHYSFDFYTEVQVVHVAV 481
>UniRef50_Q5QL36 Cluster: Glycine betaine aldehyde dehydrogenase;
n=1; Geobacillus kaustophilus|Rep: Glycine betaine
aldehyde dehydrogenase - Geobacillus kaustophilus
Length = 488
Score = 321 bits (788), Expect = 3e-86
Identities = 166/477 (34%), Positives = 267/477 (55%), Gaps = 9/477 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I EW+++ E ++++P G +I+ F + S+W + +
Sbjct: 15 YIGGEWIESLSKELIESYNPATGELISYAQNSTVEDVTQAIDATCQSF-KESDWSV-NPK 72
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R + L A + + E LA+L + + G + +SG D+++Y A + G +
Sbjct: 73 KRYEALLSLAQKMSENMERLARLLTIEQGKTIRESRVEISGCIDTLKYFAGAARAVFGRS 132
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
I + +F +K+P+GV G+I PWN P L+ + ++ ALAAG V+VKPA TP
Sbjct: 133 IQLEPKNFGVIVKEPIGVVGIISPWNWPALLMIRELAPALAAGNAVIVKPASLTPSIAVE 192
Query: 191 XXXXXKEAG-IPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
E PKG+VNIV G G G AL + ISFTG GK I + A +N +
Sbjct: 193 IFKLIDEISYFPKGIVNIVTGPGSSIGAALASSKKIDMISFTGDTSTGKKIMEMAASN-I 251
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K++ LELGGKSP I+ +DADL+ AIP G +F GQIC+A SR+ +Q I D+ +
Sbjct: 252 KKLALELGGKSPNIVFDDADLDKAIPIIGRSIFISAGQICMAGSRVLIQESIKDEVIDRL 311
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG----TAG 365
+YA+++RV N E++ GP + ++ ++ V + G++EG ++ GG R+ G
Sbjct: 312 KDYAESLRVENGLLETSDMGPLVSQNQLDIVQEYCDIGRQEGT-IITGGHRLTGGDYNKG 370
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
++ PT+ +D+ D I +EEIFGPV ++ F +E + AN++++GL+AG++TTNLN
Sbjct: 371 FFFAPTIISDLESDCRILREEIFGPVLAVQTFSNEDEALRIANDSDFGLSAGVWTTNLNR 430
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A++ S+ ++AGTVW+N Y +A FGG+K SG+GR GI + Y E K V + +
Sbjct: 431 AMKMSQGIKAGTVWINTYNKNFPEAEFGGYKQSGLGRTRGIDGLMEYCETKHVHLEI 487
>UniRef50_Q5HLA3 Cluster: Putative aldehyde dehydrogenase aldA;
n=16; Bacilli|Rep: Putative aldehyde dehydrogenase aldA
- Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 497
Score = 321 bits (788), Expect = 3e-86
Identities = 181/478 (37%), Positives = 268/478 (56%), Gaps = 13/478 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI+NE+ + GET +P +G +AKVA+ F W
Sbjct: 16 LFINNEFQASDSGETLTVSNPANGEDLAKVARAGKKDVDKAVQAAHDAFD---SWSKISK 72
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
+R L + + I E+LA +ES NG Y+ I + + +Y S+ +G
Sbjct: 73 EERADYLLEISRRIHEKTEHLATVESLQNGKPYRETSTIDVPQAANQFKYFASVLTTDEG 132
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
D ++ S + +PVGV G ++ WN PIL+ K+ ALAAG TVV++P+ TPL+
Sbjct: 133 SVNEIDQNTMSLVVNEPVGVVGAVVAWNFPILLASWKLGPALAAGNTVVIQPSSSTPLSL 192
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+E +PKGVVN++ G G ++G A+ HH V K+SFTGS +VG + +A G
Sbjct: 193 IELAKIFQEV-LPKGVVNVLTGKGSESGDAIFHHEGVDKLSFTGSTDVGYGVAQA-GAER 250
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+ TLELGGKS II +DA+L I G+ F+QG++C A SRL VQS IYD+ +
Sbjct: 251 IVPTTLELGGKSANIIFDDANLEQVIEGVQLGILFNQGEVCSAGSRLLVQSSIYDELLPK 310
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEG-ANLLAGGERIGT---- 363
E + I+VG+PFDE T Q ++K+ I+ +++ AN+L GG RI
Sbjct: 311 LKEAFENIKVGDPFDEDTKMSAQTGPEQLDKIESYIKIAEEDDKANILTGGHRITDNGLD 370
Query: 364 AGYYIQPTVFADVNDDM-TIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY+ +PT+ ++ND+ +A+EEIFGPV + KFD +E I+ AN++ YGLA GIFTT+
Sbjct: 371 KGYFFEPTII-EINDNKHQLAQEEIFGPVVVVEKFDDEQEAIEIANDSEYGLAGGIFTTD 429
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++ AL +K + G +W+N Y + APFGG+K SGIGRE A++ Y + K + I
Sbjct: 430 IHRALNVAKAMRTGRIWINTYNQIPAGAPFGGYKKSGIGREVYKDAIKNYQQVKNIFI 487
>UniRef50_Q2VLJ6 Cluster: Aldehyde dehydrogenase; n=8;
Pezizomycotina|Rep: Aldehyde dehydrogenase - Gibberella
zeae (Fusarium graminearum)
Length = 497
Score = 319 bits (784), Expect = 9e-86
Identities = 178/470 (37%), Positives = 253/470 (53%), Gaps = 10/470 (2%)
Query: 17 VDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLL 76
V A DG +F F+P G +A V + F EW D ++RG L
Sbjct: 28 VGASDGNSFPLFNPATGEKVADVPEATEDDTNRAVAAAQRAFP---EWSAMDPAKRGSYL 84
Query: 77 YKFADLIERDFEYLAKLESYDNGMVYKNCLRILSG--IPDSVRYLGSLADKIQGDTIPTD 134
K A LI+ E LA LE+ G + G S + IQG
Sbjct: 85 KKLASLIKEHNEELALLEAKSMG---RPLAEFFEGHIAASSYEHYAEAWPHIQGQASLNT 141
Query: 135 GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXX 194
+ TL+QP GV I+PWN +L F +K AL AG TVVVK +E+ PL
Sbjct: 142 PGYVTMTLRQPFGVVAAIIPWNASLLFFASKSAPALIAGNTVVVKSSEKAPLGAAKFAEL 201
Query: 195 XKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTL 254
+AG P GV N++ G G +G L H DV ISFTGS G+ IQ+AA +NLK+V L
Sbjct: 202 IHKAGFPPGVFNVLSGHGNPSGATLASHMDVRAISFTGSSPTGRAIQEAAAKSNLKKVIL 261
Query: 255 ELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAK 314
ELGGKSP+II +DADL A + ++ GQ+C+A SR+YVQ I D F++ +
Sbjct: 262 ELGGKSPVIIFDDADLEQAAKDTMYSIQWNSGQVCMANSRVYVQDSIADNFIQACKKALS 321
Query: 315 AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG-GERIGTAGYYIQPTVF 373
A + GNP ++ +GPQ D+ KV+ I GKK G L G G T G++++PT+F
Sbjct: 322 AAKSGNPTEKGINHGPQADKVQYEKVMSYINEGKKSGTLELGGNGNLDKTGGFFVEPTIF 381
Query: 374 ADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHV 433
+ +D + KEEIFGPV +I T EE I++AN+T YGL A ++T N++ A++ ++ +
Sbjct: 382 LNTPEDAKVMKEEIFGPVVNINVIKTEEEAIEKANDTEYGLYAAVYTKNVDRAMRVTQKL 441
Query: 434 EAGTVWVN-NYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+G V +N T A PFGG+K SG GRE + +++ +LE K+V++ +
Sbjct: 442 NSGYVGINCTSPTTARDLPFGGYKSSGQGREGWLYSLDNFLEVKSVMMKV 491
>UniRef50_P49189 Cluster: 4-trimethylaminobutyraldehyde
dehydrogenase; n=64; cellular organisms|Rep:
4-trimethylaminobutyraldehyde dehydrogenase - Homo
sapiens (Human)
Length = 494
Score = 319 bits (783), Expect = 1e-85
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 65 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 124
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 125 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 184
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 185 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 243
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 244 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 302
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 303 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 362
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 363 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 422
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 423 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 482
Query: 478 VIISL 482
V + +
Sbjct: 483 VCVEM 487
>UniRef50_UPI000038E2A1 Cluster: hypothetical protein Faci_03000162;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000162 - Ferroplasma acidarmanus fer1
Length = 497
Score = 318 bits (782), Expect = 2e-85
Identities = 171/484 (35%), Positives = 261/484 (53%), Gaps = 8/484 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K+FI EWV++ + + +P G +A V F + W A
Sbjct: 5 KMFIGGEWVESSENQVLKVLNPSTGLPVASVQSASRDDVGKAIDAARNSFD-SGIWSRAT 63
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQ 127
R +L K ADLIE++ + K+E+ ++G K + D++R+L ++
Sbjct: 64 PGDRSNVLLKVADLIEKNQDKFIKVETENSGKSIKQISGYDIPYTVDNIRFLAGACRTLE 123
Query: 128 GDTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G + D S ++P+G G+I PWN P++M + + ALA G +VVVKPA TPL
Sbjct: 124 GKAMNEYVADGTSAIRREPIGAIGIITPWNYPLMMVVWRAFPALAMGNSVVVKPASYTPL 183
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T KEAG+P GV N++ G G G + + I+FTGS EVGK + A +
Sbjct: 184 TTLMLADILKEAGVPDGVFNVITGPGSSVGEEMAKSEKLDMIAFTGSTEVGKRLSVLAAS 243
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N LK+V+LELGGK+P I+ DA+++ A+ A G + GQ C ++R Y+Q ++DKFV
Sbjct: 244 N-LKKVSLELGGKAPFIVFKDANIDAAVESAIVGGLVNNGQDCANSTRYYIQEEVFDKFV 302
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI----G 362
+ + +R+G+P D ST GP I E+ +V G IE G KEG LL+GGER
Sbjct: 303 SLLKKRIQKLRIGDPMDPSTDMGPLISETQRERVEGYIEKGIKEGGKLLSGGERPEIPGH 362
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GYYI P + N+D I KEEIFGPV +ILKF + I R+N+ YGL + ++T++
Sbjct: 363 KKGYYINPALIYTENEDSAIVKEEIFGPVFTILKFKDYNDAIRRSNDVTYGLGSSVWTSD 422
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ A++ ++ + GTVWVN ++ + + P+ G+K+SG G ++E + K V L
Sbjct: 423 ITTAMRATRDLRFGTVWVNEHVVVPSEMPWAGYKESGHGASLSPYSLEEFTYIKHVYFDL 482
Query: 483 PKKL 486
K+
Sbjct: 483 TGKV 486
>UniRef50_Q2SHE9 Cluster: NAD-dependent aldehyde dehydrogenase; n=6;
Gammaproteobacteria|Rep: NAD-dependent aldehyde
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 495
Score = 318 bits (781), Expect = 2e-85
Identities = 176/461 (38%), Positives = 257/461 (55%), Gaps = 10/461 (2%)
Query: 25 FDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE 84
FDT +P VI +V + F+ + W ++R +++ ++A L++
Sbjct: 34 FDTLNPFTQQVIGRVQQCNGGHVDAAVKAGRAAFE-SGVWSRLSPAERKRIMLRWAALLQ 92
Query: 85 RDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA---DKIQGDTIPTDGDSFSYT 141
E LA L+ D G CL + IPD++ + A DK+ G PT D+
Sbjct: 93 ERHEELAALDCLDAGKPITECLN--TDIPDTIHTIAWYAEAIDKLFGKISPTASDNLGLI 150
Query: 142 LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIP 201
+K+P+GV G +LPWN P LM K ALAAG ++V+KPAE T L+ EAG+P
Sbjct: 151 VKEPIGVVGAVLPWNFPALMLAWKAAPALAAGNSLVIKPAELTSLSAYRIVQLAHEAGVP 210
Query: 202 KGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSP 261
K V+ +V G GE+ G L HPDV +SFTGS EVG+L + +NLK + LE GGKSP
Sbjct: 211 KDVLTLVTGLGEETGKPLGLHPDVDMVSFTGSTEVGRLFLTYSAQSNLKEIVLECGGKSP 270
Query: 262 LIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVE-YAKAIRVG 319
I+ D+ L S F++ G+ C SRL V + DK +K + +VG
Sbjct: 271 QIVFEDSYALEEIADSILSAAFWNMGENCSCGSRLIVHKSVKDKLLKILQKRLVDGWKVG 330
Query: 320 NPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT-AGYYIQPTVFADVND 378
+P D T GP I+ + KV G I+T K EGA L+ GGE + AG ++PT+F V
Sbjct: 331 DPQDPETAIGPMIEPAHFEKVCGYIKTAKGEGAKLIRGGEALKLGAGMSVEPTIFDGVTA 390
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+MT+ +EE+FGPV ++ F+T E I AN TNYGLAA ++T++L A + S+ ++AGTV
Sbjct: 391 EMTLFQEEVFGPVLAVTTFETEAEAIHLANATNYGLAASLYTSDLRRAQRVSRAIKAGTV 450
Query: 439 WVNNYLTMAHQAPFGGFKDSGI-GRENGIKAVEAYLEEKTV 478
+N + PFGG+K SG GR+ G++A+E Y++ KT+
Sbjct: 451 SINCFSEGDIATPFGGYKTSGFGGRDKGLEALEQYVQTKTL 491
>UniRef50_Q39NZ7 Cluster: Succinic semialdehyde dehydrogenase; n=13;
cellular organisms|Rep: Succinic semialdehyde
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 502
Score = 317 bits (779), Expect = 4e-85
Identities = 170/471 (36%), Positives = 259/471 (54%), Gaps = 7/471 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T+ ++ + W + DG +F +P G ++A+VA Q W+
Sbjct: 31 TRAWLASGWQEGTDGRSFPVTNPATGDILARVASLGAAEVEQAIESSALAQQG---WQKR 87
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+ +R KLL + DLI + + LA + + + G ++ V + A ++
Sbjct: 88 TSHERAKLLRAWFDLILANADDLALIMTSEQGKPLAEARGEITYAASFVEWFAEEAKRVY 147
Query: 128 GDTIP-TDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD +P GD ++QP+GVC I PWN P M KV ALAAGC+++V+PA+ TPL
Sbjct: 148 GDVMPHPQGDKRILVIRQPIGVCAAITPWNFPAAMITRKVAPALAAGCSIIVRPADLTPL 207
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGK-LIQKAAG 245
T + AGIP GV+ +V G + G LT P V K+SFTGS EVG+ L+ +++G
Sbjct: 208 TALALAVLAERAGIPAGVLQVVCGPSREIGAVLTASPVVRKLSFTGSTEVGRVLMSQSSG 267
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
T +KR++LELGG +P I+ +DADL+ AI A + + + GQ CV A+R VQ+GI+D+F
Sbjct: 268 T--IKRLSLELGGNAPFIVFDDADLDAAIEGAMASKYRNSGQTCVCANRFLVQAGIHDRF 325
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
V+ +A++VGN + GP I +S + + LI+ +GA ++ GG+ G
Sbjct: 326 VEALTRRVQALKVGNGIEPGVQQGPLIQKSACDHLNQLIDDAVSKGARIVTGGKGHPLGG 385
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
+ +PTV AD M +A+EE+FGPV + +FD E I AN+T YGLAA ++T + +
Sbjct: 386 TFFEPTVIADATPAMRLAREELFGPVGPVFRFDDEAEAIAMANDTEYGLAAYLYTRDNSR 445
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ + +E G V +N + APFGG K SG+GRE +E YLE K
Sbjct: 446 IWRVGEALEYGMVGLNTGVISNEVAPFGGVKQSGLGREGSRYGIEEYLEIK 496
>UniRef50_Q5V606 Cluster: Aldehyde dehydrogenase; n=2;
Halobacteriaceae|Rep: Aldehyde dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 503
Score = 317 bits (778), Expect = 5e-85
Identities = 168/423 (39%), Positives = 237/423 (56%), Gaps = 6/423 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W + R + L ++ D++E + LA LE D G + G ++ Y ++A
Sbjct: 78 WSDRTPTDRSQRLSEWVDVLEEHLDELALLECLDTGKPLSEARGEVEGALRTLEYYAAVA 137
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
QG IP GD YT +P GV G I PWN P K ALAAG V+KP+
Sbjct: 138 RTQQGSQIPAQGDLHMYTRMEPYGVVGQITPWNFPAWAAAWKFGPALAAGNCSVLKPSAY 197
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT + P GV+N+V G G G LT H DV K+SFTGS VG+ + +
Sbjct: 198 TPLTTVRMAQLS-DGIFPDGVINVVTGGGSTTGATLTEHEDVRKLSFTGSGSVGQEVMQT 256
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A + VTLELGGKSPL++ DAD+ A+ A +GV++ G+IC A SR V ++D
Sbjct: 257 AAAR-IAPVTLELGGKSPLLVFPDADMQTAVDAAAAGVYYSTGEICDALSRAIVHEDVHD 315
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----E 359
+FV V A++ +G+P D+ T GP +E V + G+ EGA L GG +
Sbjct: 316 EFVDRLVARAESYTLGDPLDDETTLGPLTNEDQFETVSDYVTIGRNEGATLATGGTAPDD 375
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
R G+Y++P VF DV DM IA+EEIFGPVQ++ F+T +E I AN+T +GLA G+
Sbjct: 376 RALADGHYVEPAVFTDVEPDMRIAREEIFGPVQTVQSFETYDEAIALANDTEFGLAGGVA 435
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T + + A Q + ++AG V++N Y + + P+GGFK+SGIG + G AVE Y + KTV
Sbjct: 436 TESTDIAHQAAADIDAGVVYINAYGPIRPEGPYGGFKESGIGHDLGRAAVEQYQQPKTVY 495
Query: 480 ISL 482
++L
Sbjct: 496 VNL 498
>UniRef50_A5V6Y8 Cluster: Aldehyde dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Aldehyde dehydrogenase - Sphingomonas
wittichii RW1
Length = 494
Score = 316 bits (777), Expect = 6e-85
Identities = 166/421 (39%), Positives = 245/421 (58%), Gaps = 5/421 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSL 122
WR ++R ++L++ A+LIERD ++LA+LE+ + G + L ++ ++ RY
Sbjct: 72 WRGRTPAERQRILWRIAELIERDAQFLAELETLNGGKPFGAALHGEVAAAAETFRYYAGW 131
Query: 123 ADKIQGDTIPTD--GDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
KI G T G SF Y +PVGV GLI PWN P+++ K+ ALAAGC ++K
Sbjct: 132 VTKIDGGTFDPSVPGQSFLGYGRHEPVGVAGLITPWNGPLVIAAWKLAPALAAGCCAILK 191
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
P+E TP T EAG+P+GVV ++PG G G AL HP + KISFTGS VG+
Sbjct: 192 PSELTPFTTLHLAALALEAGVPEGVVQVLPGTGATVGSALARHPGIDKISFTGSTAVGRR 251
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
+ A + +LKR++LELGGKSP++I DADL+ A A +F + GQ+CVA SR+YV+
Sbjct: 252 LM-ADASGDLKRLSLELGGKSPVLIFADADLDRAAAGAADAIFGNAGQVCVAGSRVYVER 310
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
I V+ + A +R+G FD T GP I + V G + ++ GA ++ GG
Sbjct: 311 SIEAALVERLADIAGRMRIGPGFDSLTQMGPLISDRHRAGVDGFVRRAREAGAAVVTGGA 370
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
I G++ PT+ D + + E+FGPV ++ FD E + AN+++YGLAA I+
Sbjct: 371 PIDGPGFFYPPTIVTGCRQDSELVQGEVFGPVLAVQPFDDEAEAVRLANDSSYGLAASIW 430
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T ++ A + + V AG VWVN++ P GG K SGIGRE+G +EA+ E K+V+
Sbjct: 431 TRDVGRAHRVAADVRAGIVWVNSHGIPELAMPIGGMKQSGIGREHGWAGLEAFTEFKSVM 490
Query: 480 I 480
+
Sbjct: 491 L 491
>UniRef50_Q39A62 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|Rep:
Aldehyde dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 487
Score = 316 bits (776), Expect = 8e-85
Identities = 178/472 (37%), Positives = 251/472 (53%), Gaps = 7/472 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L+ID W A G P G IA+VA G F EW
Sbjct: 5 QLYIDGAWQPAAAGGQRAIIDPATGEAIARVAYGSAADAGHAIRAARAAFDAG-EWPHLP 63
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A +R L + A+ + + LA++E+ + G + + Y SLA G
Sbjct: 64 AEERAACLRRLANALRDEAPALARIETANTGKTLAESSSDVHDAASAFDYFASLAVTETG 123
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
S TL++PVGVCGLI PWN P+L K+ AL AG TVVVKPA TPL+
Sbjct: 124 SMNAAKPHVISVTLREPVGVCGLITPWNYPLLQAAWKLAPALVAGNTVVVKPASLTPLST 183
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+AG+P+GV+N+V G G D G AL P V IS TGS G + +AA N
Sbjct: 184 HRLVELAHDAGLPRGVLNLVTG-GADVGDALAASPQVDLISLTGSNAAGASVMRAAA-GN 241
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
KRV+LELGGK+P ++ DAD++ A+ YA + FF+ GQ+C A SRL V+ ++D FV
Sbjct: 242 FKRVSLELGGKNPNLVFADADVDTALDYALNAAFFNAGQMCSAGSRLLVERTLHDAFVDA 301
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER-IGTA--- 364
AIRVG D++T GP I ++VL LI ++GA ++ GG G A
Sbjct: 302 LAARIAAIRVGRGDDDATRMGPVISAQQRDRVLALIGEAARDGARIVCGGRAPAGDAFAT 361
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G++++PT+ A V M IA+EE+FGPV ++ FD+ +E + AN+T +GLA ++T +
Sbjct: 362 GFWVEPTLIAGVRTTMAIAREEVFGPVLTVEAFDSEDEAVALANDTPFGLAGAVWTRDFA 421
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
A + + + A TVW+N+Y AP+GG+K SGIGRE ++ Y E K
Sbjct: 422 RANRVMRRLRAATVWINDYNVTLPGAPWGGYKASGIGRELSRSGLDEYTELK 473
>UniRef50_P42329 Cluster: Aldehyde dehydrogenase, thermostable;
n=12; Bacillaceae|Rep: Aldehyde dehydrogenase,
thermostable - Bacillus stearothermophilus (Geobacillus
stearothermophilus)
Length = 488
Score = 316 bits (776), Expect = 8e-85
Identities = 183/485 (37%), Positives = 266/485 (54%), Gaps = 12/485 (2%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
EIK +I+ WV + + +P + I V Q + +
Sbjct: 6 EIKTYFNYINGNWVSSVSNNVEPSINPANRHDI--VGYVQRSTLEDVNEAVTAANEAQTS 63
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
W +RG+ LYK A ++E+ + +A+ + + G + G+ Y G
Sbjct: 64 WWKRSGVERGEYLYKAAHILEQCLQDIAETMTREMGKTLAEAKAETMRGVHILRYYAGEG 123
Query: 123 ADKIQGDTIPT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
A KI GD IP+ D + +T + P+GV G+I PWN P+ + + K+ AL G TVV+KPA
Sbjct: 124 ARKI-GDVIPSSDSEGLLFTTRVPLGVVGVISPWNFPVAIPIWKMAPALVYGNTVVLKPA 182
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
+T +T EAG PKGVVN+V G G G + +HPD+ ++FTGS VGK +
Sbjct: 183 SETAVTAAKVIECFHEAGFPKGVVNMVCGSGSVVGQGIANHPDIDGVTFTGSNTVGKQVG 242
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
+AA K LE+GGK+P+I+ DADL+LA+ SG GQ C A SR++++ +
Sbjct: 243 RAAFERGAK-YQLEMGGKNPVIVAKDADLDLAVEGTISGGLRSTGQKCTATSRVFIEREV 301
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y+ F +E K +++GN D T GP ES + VL IE GK EGA L+ GG R
Sbjct: 302 YEPFKAKLLERVKQLKIGNGLDAETWMGPCASESQFHTVLSYIEKGKSEGAKLIYGGNRC 361
Query: 362 --G--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G G++++PT+F DV+ MTIA+EEIFGPV ++++ D++EE I AN+T YGL+A
Sbjct: 362 LEGELANGFFVEPTIFEDVDLQMTIAREEIFGPVLALIQVDSIEEAIKLANDTEYGLSAS 421
Query: 418 IFTTNLNNALQFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGI-GRENGIKAVEAYLEE 475
I+T N+ NAL+F K +EAG + VN + QAPFGG K S RE G A+E +
Sbjct: 422 IYTKNIGNALEFIKDIEAGLIKVNAETAGVEFQAPFGGMKQSSSHSREQGQAAIEFFTSI 481
Query: 476 KTVII 480
KTV +
Sbjct: 482 KTVFV 486
>UniRef50_Q47PW2 Cluster: Betaine-aldehyde dehydrogenase; n=1;
Thermobifida fusca YX|Rep: Betaine-aldehyde
dehydrogenase - Thermobifida fusca (strain YX)
Length = 490
Score = 315 bits (774), Expect = 1e-84
Identities = 176/480 (36%), Positives = 261/480 (54%), Gaps = 14/480 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI WVD+K G D +P G+ + F + W
Sbjct: 15 QLFIGGRWVDSKGGRKVDVHNPATGAYVGSTVLASTADIDAAVASARASFN-SGVWANTP 73
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYL---GSLADK 125
+R +L++ ADL+E LAKL + + G R + +P+ +R+L G+LA
Sbjct: 74 PEERAAVLHRAADLLEERAPELAKLITSELGCPIWFSER--AHVPNPIRHLRYYGTLAKD 131
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
D +DG + S + PVGV I PWN P+ KV ALAAGC+V++KP +TP
Sbjct: 132 FAYDERRSDGTNTSLVTQVPVGVVAAITPWNGPLSTPSLKVAPALAAGCSVILKPPPETP 191
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AG+P GV+NIVP E+ G L HPDV K++FTGS GK I AA
Sbjct: 192 LTAYNLADALSQAGLPDGVLNIVPADREE-GAYLVSHPDVDKVAFTGSSAAGKKIM-AAC 249
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+ RVTLELGGKS II++DAD++ +P F GQ C+A +RL V D+F
Sbjct: 250 AERIARVTLELGGKSAAIILDDADVDTVVPALLPMAFMVNGQACIAQTRLLVPRSRKDEF 309
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--- 362
+ + A RVG+P D +T GP + +V G I TG++EGA ++ GGER
Sbjct: 310 IDAFAQAVAAQRVGDPIDPATQIGPMVSRRQQERVEGYIATGRQEGARVVVGGERPSLPS 369
Query: 363 --TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G+++ PT+ A+V++ M +A+EEIFGPV +++++D +E + AN++ YGL+ +++
Sbjct: 370 ELAGGWFVAPTLLAEVHNSMRVAQEEIFGPVLAVIEYDGDDEAVAIANDSVYGLSGSVWS 429
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++ AL ++ + G V +N A +PFGGFK SGIGRE G + AYLE ++ +
Sbjct: 430 SDEERALAIARRMRTGMVSING-RPQAANSPFGGFKQSGIGREMGPEGFHAYLETMSIAV 488
>UniRef50_Q1LEY1 Cluster: Aldehyde dehydrogenase; n=4; Bacteria|Rep:
Aldehyde dehydrogenase - Ralstonia metallidurans (strain
CH34 / ATCC 43123 / DSM 2839)
Length = 496
Score = 315 bits (774), Expect = 1e-84
Identities = 176/478 (36%), Positives = 251/478 (52%), Gaps = 10/478 (2%)
Query: 16 WVDAKD----GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
WVD TFD+ +P G V +VA + WR
Sbjct: 12 WVDGVSVFTPARTFDSVNPATGEVNWQVAFATAEHVAAAVASAKRAVN-DPAWRKMLPHV 70
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTI 131
R +L + AD + + A+L+ +NG V+ C + R+ S + + +
Sbjct: 71 RAGILMRIADAMTARADEFARLQMLENGKVWSECRAQALSAASTFRFYASACETLGSEVT 130
Query: 132 PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXX 191
P+ G+ S T +P GV I PWN P+ M KV ALAAG V++KP+E TP
Sbjct: 131 PSRGNYLSMTAYEPYGVVAAITPWNSPLTMEAQKVAPALAAGNAVILKPSEVTPSGALLL 190
Query: 192 XXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKR 251
EAG+PKG++N+V G G + G AL HPDV +SFTG G+ I A L
Sbjct: 191 AQVAFEAGLPKGLLNVVTGDGRETGTALVEHPDVRMVSFTGGTATGRSIAGIA-AQRLIP 249
Query: 252 VTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVE 311
V LELGGKSP II DA+++ AI G+F GQ CVA SRL+VQ IYDK V VE
Sbjct: 250 VALELGGKSPHIIFEDANIDAAINGVVDGIFEGSGQSCVAGSRLFVQRSIYDKAVGLLVE 309
Query: 312 YAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER----IGTAGYY 367
A+A+RVG P + GP + ++V + ++EG +LAGG R AG +
Sbjct: 310 RARALRVGLPDVAGSQLGPLAGFAHRDRVERFVSIAREEGGQILAGGRRPPEAALQAGAF 369
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+PTV +++ T ++EIFGPV +L F +++I +AN++ +GLA+GI+T N A
Sbjct: 370 FEPTVIGGLSNSATAVQQEIFGPVLCVLPFGDEDDLIAQANDSAFGLASGIWTANYQRAW 429
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
+ ++ +E G VW+N Y ++ PFGGFKDSGIGRE G+ V Y + K + S+ +K
Sbjct: 430 RVARALETGLVWINTYKQLSIATPFGGFKDSGIGREKGVNGVRLYQQSKGIYWSMDEK 487
>UniRef50_A1WPM7 Cluster: Betaine-aldehyde dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: Betaine-aldehyde
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 489
Score = 315 bits (774), Expect = 1e-84
Identities = 180/478 (37%), Positives = 263/478 (55%), Gaps = 8/478 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L ID + + G+ FD +P G V+A+V + F ++ WR A
Sbjct: 14 LLIDGQERSSSAGQHFDVDNPSTGRVLAQVTQADANDVDAAVRAAQTAF--DTHWRHTSA 71
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
QR +LL K AD +ER E LA LE+++ G L + D + Y+ +A I G
Sbjct: 72 RQRSRLLRKLADALERRTEQLAWLETWNVGRPITLTRATLGTMLDGIDYVAGVAQGIGGQ 131
Query: 130 TIPT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T D ++TL++P GV GLILPWN P+ + ++K++ LAAG T V+K +E TPL+
Sbjct: 132 THNVADTHIVNFTLREPYGVVGLILPWNYPLTLTISKLMPVLAAGNTAVIKASEITPLST 191
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
EAG P GV+NIV G G G AL HP V +ISFTG GK I ++A
Sbjct: 192 VELGAAILEAGFPPGVINIVHGPGATVGQALVEHPLVERISFTGGTATGKAIYRSA-AER 250
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+KRVTLELGGKSPLI+ +DADL+LA A V + GQICVA +RL V I + F +
Sbjct: 251 IKRVTLELGGKSPLIVFDDADLDLAAAIALQDVTKNSGQICVACTRLLVHERIAEAFTER 310
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---- 364
+ + IRVG P D T GP + + + +V I+ G+ E AN + G A
Sbjct: 311 LRQAYQHIRVGLPEDPQTQMGPLVSRAQLERVQRYIDIGRDEQANPEVLQDLSGRAELRN 370
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GY++ PT+F M +A++EIFGPVQ ++ F + + AN++ +GLA + T +
Sbjct: 371 GYFVAPTLFTQGRSGMQVAQDEIFGPVQVVIPFRDEADAVRIANDSRHGLAGVVCTRDGA 430
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A++ ++ G + +N+ + ++ APFGGFK+SG+G+E GI A+ + K V S+
Sbjct: 431 RAMRMCHALQIGNIAINDPIKVSVDAPFGGFKESGLGKERGIDAILENTQVKNVRFSM 488
>UniRef50_Q0U8X3 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 495
Score = 314 bits (772), Expect = 3e-84
Identities = 163/449 (36%), Positives = 247/449 (55%), Gaps = 8/449 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L IDN +V + +G T + H G+ + +A ++ + W+ +
Sbjct: 22 LLIDNVFVPSVEGATLQVQNAHSGATVGAIASATQKDVNAAVKSSSQAYE--TVWKFSTG 79
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQG 128
+ R +LL K ADLIERD + A LE+ D G + + L + + +RY ADK+ G
Sbjct: 80 ATRRQLLNKLADLIERDLQLFATLEAIDIGQLVSTNIGALGPMAVEWLRYFAGWADKLDG 139
Query: 129 DTIPTDGDS----FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
+ D S SYT+++P GV I+PWN P+++ K+ +AAG T+++K E
Sbjct: 140 RSANWDAGSERQGLSYTIREPYGVTAAIVPWNTPLMLSCWKIAPCIAAGNTLILKSPELA 199
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
PL+ EAG P GV+NI+ G G AG AL HH + KI+FTGS G+ I +A+
Sbjct: 200 PLSCLHLAQLIVEAGFPPGVINIITGLGTVAGAALAHHMQIRKIAFTGSTLTGRSILRAS 259
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+NLK+V+L+LGGKSP II DAD + A+ +A G+ +G++C A SR+YVQ IY K
Sbjct: 260 ADSNLKKVSLKLGGKSPTIIFADADFDDAVEWAAVGITLGEGEVCAAGSRIYVQDSIYQK 319
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
F++ K G+P T GP I + +KV+ I+ K G +L GG +
Sbjct: 320 FLQAFANRCKTAIAGDPLAPQTAKGPLISKQQRDKVMSYIDDAKSRGIKVLFGGTSDAPS 379
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
+ T F DV +D+ + KEE+FGPV +I F T +EV+ +AN++ YGLAA +FT +L
Sbjct: 380 N-VVANTAFVDVPEDVPLMKEEVFGPVAAIASFTTEDEVVQKANDSEYGLAASVFTRDLV 438
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFG 453
A + + +++G V VN + +A PFG
Sbjct: 439 RAHRVAARLQSGQVTVNAWGMLAANMPFG 467
>UniRef50_Q8YD95 Cluster: ALDEHYDE DEHYDROGENASE; n=75;
Bacteria|Rep: ALDEHYDE DEHYDROGENASE - Brucella
melitensis
Length = 536
Score = 314 bits (771), Expect = 3e-84
Identities = 175/474 (36%), Positives = 260/474 (54%), Gaps = 10/474 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI +W DA GE +P DGS +A +A+G + +W A+
Sbjct: 66 FIAGQWQDAVGGEHITLKNPSDGSDLALIARGAKADIDLAVVAARSAL--SGDWGKLTAT 123
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+RG++L++ ++ + ++ + L LES D G + + + + G+ ADK+ GDT
Sbjct: 124 ERGRILHRISEEVLKNIDLLTDLESKDVGKPVTQARVDVVALARYLEFYGASADKVHGDT 183
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+P ++ +P GV G I+PWN P+ + + ALA G VVKPAE+ LT
Sbjct: 184 LPYQNGFTVLSIYEPHGVTGHIIPWNYPMQILGRSLGAALAMGNAAVVKPAEEACLTILE 243
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
++AG+PKG +N+V GFG +AG AL HPDV ISFTGS+ G+++Q AA N +
Sbjct: 244 FARIAEKAGLPKGALNVVTGFGAEAGAALCEHPDVNHISFTGSVRTGEVVQAAAAKNTVP 303
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGKSP I+ DADL+ A+P+ + + GQ C A+SR+ V+ IY++ +
Sbjct: 304 -VTLELGGKSPQIVFADADLDRALPFLVNAGIQNAGQTCSASSRILVERSIYEEVIARMS 362
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG---ERIGTAGYY 367
E +A++VG P GP + + V G ++ K+ G + A G E G Y
Sbjct: 363 ERYRALKVG-PASADLSVGPVVSQRQKAIVDGYLDLAKESGLAIAAQGVLAEGAPEGGAY 421
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+ PT+ DV D +A+EEIFGPVQ IL FDT EE I AN T+YGL GI+T +
Sbjct: 422 VLPTLIRDVPADHRLAQEEIFGPVQVILPFDTEEEAI--ANGTHYGLVCGIWTNDGGRQF 479
Query: 428 QFSKHVEAGTVWVNNY-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ + + +G V++NNY + PFGG K SG GRE G +A+ + KT+ +
Sbjct: 480 RLAHAIHSGQVFINNYGAGGGIELPFGGVKKSGHGREKGFEALYGFASLKTISV 533
>UniRef50_Q8Y8I9 Cluster: Lmo0913 protein; n=11; Listeria|Rep:
Lmo0913 protein - Listeria monocytogenes
Length = 488
Score = 314 bits (770), Expect = 4e-84
Identities = 173/482 (35%), Positives = 272/482 (56%), Gaps = 12/482 (2%)
Query: 2 VPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRN 61
+P+++ TKLFI+ +W D + ET D +P +G VIAK+A+ F
Sbjct: 8 LPKVQ-TKLFINGKWTDGDNKETKDIVNPANGDVIAKIAQAGPSETKKAIKAAKDAFP-- 64
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL-RILSGIPDSVRYLG 120
+W + + R KLL+K ADL+E + LAK+ + + G K +L+G+ ++ R+
Sbjct: 65 -DWAKMELADRVKLLHKIADLMEEKADTLAKIMTLEQGKPLKESKGEVLTGV-ENFRFAA 122
Query: 121 SLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
A ++ G+TIP + KQP+GV I PWN P M K+ ALA G T+V+KP
Sbjct: 123 EEARRLYGETIPAPNNHAFIVKKQPIGVVAAITPWNFPGGMVTRKLAPALATGNTIVLKP 182
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
+ TPL+ +EAG+PKGV NIV G ++ G LT DV K++FTGS +VG+ +
Sbjct: 183 SGDTPLSALAIFEIFEEAGLPKGVANIVMGSSKEIGETLTDSDDVRKLTFTGSTKVGQTL 242
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
K + + LK+++LELGG +P I+ +DA+L+ A+ + F + GQ+CV+ +R++V
Sbjct: 243 FKQS-ADTLKKISLELGGHAPFIVFDDANLDAAVNDLVAAKFRNNGQVCVSPNRIFVAKE 301
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
I +KF K V + ++VGN D+ V GP I E ++K+ ++ ++GA +L GG R
Sbjct: 302 IKEKFTKALVAKVEQLKVGNGLDDVNV-GPLIREDAIDKIDKQLKNATEKGAKVLTGGGR 360
Query: 361 IGTAGY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
+ + Y + +PTV +V M I EE FGPV ++ F+T +E I+ AN++ +GLA+
Sbjct: 361 LTGSDYDKGNFYKPTVLDNVTRKMDIFYEETFGPVIPLITFETEDEAIEMANDSEFGLAS 420
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+T +L + +E G V N + PFGG K SG GRENG +E Y++ K
Sbjct: 421 YFYTKDLARVEKVGAALEYGMVGANEIAISNPETPFGGVKHSGFGRENGHYGMEEYIQVK 480
Query: 477 TV 478
+
Sbjct: 481 FI 482
>UniRef50_O24174 Cluster: Betaine aldehyde dehydrogenase; n=6;
Viridiplantae|Rep: Betaine aldehyde dehydrogenase -
Oryza sativa subsp. japonica (Rice)
Length = 505
Score = 314 bits (770), Expect = 4e-84
Identities = 177/477 (37%), Positives = 252/477 (52%), Gaps = 9/477 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS--EWRLA 67
LFI W + G +P + I + F R+ W A
Sbjct: 12 LFIGGGWREPSLGRRLPVVNPATEATIGDIPAATAEDVELAVSAARDAFGRDGGRHWSRA 71
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+ R K L A I+ YLA LE+ D+G + + Y LA+ +
Sbjct: 72 PGAVRAKYLKAIAAKIKDKKSYLALLETLDSGKPLDEAAGDMEDVAACFEYYADLAEALD 131
Query: 128 GDT---IPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G I ++F SY LK+P+GV GLI PWN P+LM KV ALAAGCT V+KP+E
Sbjct: 132 GKQRAPISLPMENFESYVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCTAVLKPSEL 191
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
LT E G+P GV+NI+ G G +AG L HP V KI+FTGS E GK I
Sbjct: 192 ASLTCLELGGICAEIGLPPGVLNIITGLGTEAGAPLASHPHVDKIAFTGSTETGKRIMIT 251
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A + +K V+LELGGKSPLI+ +D D++ A+ +A G F + GQ+C A SRL + I
Sbjct: 252 A-SQMVKPVSLELGGKSPLIVFDDVDIDKAVEWAMFGCFANAGQVCSATSRLLLHEKIAK 310
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG- 362
+F+ V +AK+I++ +P +E G + E K++ I T + EGA +L GG R
Sbjct: 311 RFLDRLVAWAKSIKISDPLEEGCRLGSVVSEGQYQKIMKFISTARCEGATILYGGARPQH 370
Query: 363 -TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G++I+PT+ +V+ M I +EE+FGPV + +F T E ++ AN+T+YGLA + +
Sbjct: 371 LKRGFFIEPTIITNVSTSMQIWREEVFGPVICVKEFRTEREAVELANDTHYGLAGAVISN 430
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+L + SK +++G VW+N QAP+GG K SG GRE G ++ YL K V
Sbjct: 431 DLERCERISKAIQSGIVWINCSQPCFVQAPWGGNKRSGFGRELGQWGLDNYLSVKQV 487
>UniRef50_Q5FQ94 Cluster: Aldehyde dehydrogenase; n=1; Gluconobacter
oxydans|Rep: Aldehyde dehydrogenase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 480
Score = 313 bits (769), Expect = 6e-84
Identities = 172/477 (36%), Positives = 259/477 (54%), Gaps = 9/477 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI+ WV K GE +P +V+A+VAKG F W A
Sbjct: 7 LFINGSWVAPKGGEWIKVENPATKAVVAEVAKGGQADVDAAVSAAKSAF---IGWSRRTA 63
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
++R ++ DL++RD E LA + + + G K + +R+ ++QG+
Sbjct: 64 TERADYIHALKDLVKRDKEKLAAIITSEMGKPLKEARIEVDFAIGLLRFSAENVLRLQGE 123
Query: 130 TIPTDGDSFSYTLKQ-PVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
IP + + P+GV G I WN P+ + K+ A+AAG T+VVKP E TPL
Sbjct: 124 IIPGSSPEEKILIDRVPLGVIGAITAWNFPLALCARKIGPAVAAGNTIVVKPHELTPLAC 183
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+EA IP GV+N+V G G+D GV L H D+ I+ TGS GK I AA +
Sbjct: 184 LHLAKLVEEAKIPHGVINVVTGDGKDVGVPLVAHKDIKLITMTGSTPAGKKIM-AAASET 242
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LK V LELGGK+P ++M DAD++ A A + F + GQ+C R Y+ +YD+FV+
Sbjct: 243 LKEVRLELGGKAPFMVMEDADIDRAADAAVTARFNNAGQVCTCNERTYIHEAVYDRFVQK 302
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER----IGTA 364
E +A++VG P D ST GP++ E +NKV ++E ++GA L GG+R +
Sbjct: 303 VREKIEALKVGLPTDPSTDMGPKVSEDELNKVHEMVEHAVRQGARLAIGGKRLTGGVYDK 362
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GY+ PT+ DV DM I E+FGPV S+++ ++ I AN+ YGL+A +FT +L+
Sbjct: 363 GYFYAPTLLTDVTQDMDIVHNEVFGPVMSLIRVKDFDQAIAWANDCRYGLSAYLFTNDLS 422
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
L+ ++ +E G V+VN A Q G+K+SG+G E+G +EAY++ KT+ ++
Sbjct: 423 RILRMTRDLEFGEVYVNRPGGEAPQGFHHGYKESGLGGEDGQHGMEAYVQTKTIYLN 479
>UniRef50_A1RDQ2 Cluster: Aldehyde dehydrogenase; n=4;
Actinobacteria (class)|Rep: Aldehyde dehydrogenase -
Arthrobacter aurescens (strain TC1)
Length = 455
Score = 313 bits (769), Expect = 6e-84
Identities = 168/417 (40%), Positives = 243/417 (58%), Gaps = 6/417 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W ++R L+ AD + + LA LES D G + + G+ + +Y
Sbjct: 41 WVRKPLAERRDALWAIADAVIAHSDELALLESTDVGKPLAAARQEVLGVAECFKYYAGTV 100
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DKI GDTIP DG S T ++P+GV +I PWN P+ + + ALA+G +V+VKPA
Sbjct: 101 DKILGDTIPVDG-GVSMTFREPLGVVAVIAPWNFPLPIASWSIAPALASGNSVIVKPAAL 159
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPL+ KE G+ + ++ G G G AL HPDV+KISFTGS EVG+ I +A
Sbjct: 160 TPLSTVRFGEIVKELGVVGDALQVLTGSGARIGNALAEHPDVSKISFTGSTEVGRSIVQA 219
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A T +KRV+LELGGKS I+ ND DL + A VF + GQ C A SR VQ GI+D
Sbjct: 220 ASTT-MKRVSLELGGKSASIVYNDVDLGKCLQAAPMSVFDNTGQDCCARSRFLVQRGIFD 278
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+G +E +A+++GNP D T GP + + + V +E G N++ GE
Sbjct: 279 EFVEGFIETTRALKIGNPLDGKTDLGPLVSAAHRDTVSSFLENG----LNVVTAGEAPDG 334
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G+++ P + + +A +EIFGP+ S++ FDT EE I AN++ YGL+ I+T ++
Sbjct: 335 PGFWMAPRIVIAPDPKSRVATDEIFGPIASVIPFDTEEEAIALANSSIYGLSGSIWTNDV 394
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
AL+ ++ +E+GT+ VN+ ++ Q P+GGFK SGIGR G A+EAY E KTV +
Sbjct: 395 GQALRTARALESGTLSVNSNSSIRIQTPYGGFKQSGIGRGLGQAAIEAYTELKTVFV 451
>UniRef50_O85973 Cluster: Benzaldehyde dehydrogenase; n=8;
Proteobacteria|Rep: Benzaldehyde dehydrogenase -
Sphingomonas aromaticivorans
Length = 501
Score = 312 bits (767), Expect = 1e-83
Identities = 165/479 (34%), Positives = 263/479 (54%), Gaps = 15/479 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I EW+ G+T D +P G V+ K+ G F + W +
Sbjct: 21 YIGGEWIAGDSGKTIDLLNPSTGKVLTKIQAGNAKDIERAIAAAKAAFPK---WSQSLPG 77
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV---RYLGSLADKIQ 127
+R ++L + A ++ + A LE+ +NG + + +P ++ A +
Sbjct: 78 ERQEILIEVARRLKARHSHYATLETLNNGKPMRESMYF--DMPQTIGQFELFAGAAYGLH 135
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
G T+ D+ ++P+GVC I+PWNVP+LM K+ ALA+G TVV+KPAE L+
Sbjct: 136 GQTLDYP-DAIGIVHREPLGVCAQIIPWNVPMLMMACKIAPALASGNTVVLKPAETVCLS 194
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+ +P GV+N+V G+G D G AL PDVAK++FTGS+ + I + A N
Sbjct: 195 VIEFFVEMADL-LPPGVINVVTGYGADVGEALVTSPDVAKVAFTGSIATARRIIQYASAN 253
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
+ + TLELGGKS I+ DAD++ A+ A ++G++C+A SRL++ I D+F+
Sbjct: 254 IIPQ-TLELGGKSAHIVCGDADIDAAVESATMSTVLNKGEVCLAGSRLFLHQSIQDEFLA 312
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--- 364
+ IR G+P D +T G Q + +KV + +EGA +L GG R A
Sbjct: 313 KFKTALEGIRQGDPLDMATQLGAQASKMQFDKVQSYLRLATEEGAEVLTGGSRSDAADLA 372
Query: 365 -GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G +I+PTVF +VN+ M IA+EEIFGPV S++ + ++++ +ANNT YGLA G++T ++
Sbjct: 373 DGNFIKPTVFTNVNNSMRIAQEEIFGPVTSVITWSDEDDMMKQANNTTYGLAGGVWTKDI 432
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + ++ +E GTVW+N Y + P GG+K SG GRE + + Y + K+V+++L
Sbjct: 433 ARAHRIARKLETGTVWINRYYNLKANMPLGGYKQSGFGREFSHEVLNHYTQTKSVVVNL 491
>UniRef50_Q11K50 Cluster: Aldehyde dehydrogenase; n=49; cellular
organisms|Rep: Aldehyde dehydrogenase - Mesorhizobium
sp. (strain BNC1)
Length = 499
Score = 312 bits (765), Expect = 2e-83
Identities = 167/486 (34%), Positives = 254/486 (52%), Gaps = 7/486 (1%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E+ +KL+I W + E FS DGSV +V KG Q +
Sbjct: 5 ELPSSKLYIGGRWEEGSGAEIVSIFSG-DGSV-NRVIKGASRADGERAIERALKAQSDPA 62
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
WR +R + L++ AD IE + +A +++ D G + +++ + RY
Sbjct: 63 WRNLKPHERARFLHRIADGIETNAARIAFIQTRDTGKTLRETTALVASAAGTFRYFAGAL 122
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ + GD S ++ +P+G+ I PWN PI KV ALAAG V++KPA
Sbjct: 123 ESLDDTLTAPRGDYLSMSVHEPLGLVSAITPWNSPIASDAQKVAPALAAGNAVLLKPASW 182
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
+PL + AG+P+G+ +++PG G + G L HP ++++SFTG G+++ +
Sbjct: 183 SPLVSLELARIVEAAGLPQGLFSVLPGAGREIGNLLVEHPAISRVSFTGGTATGRMLARQ 242
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A L ++LELGGKSP I+ DAD++LAI GVF GQ C+A SRL+V+ IY+
Sbjct: 243 A-AEKLMPISLELGGKSPTIVFADADIDLAIAGILFGVFSSSGQSCIAGSRLFVERSIYE 301
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
FV V K + VG+PFDE T P + + V + + GA +L G
Sbjct: 302 SFVDRLVAATKKLVVGDPFDERTQVAPLVHFDHRDAVAAQVAAAVEAGAEVLCGAAIPTG 361
Query: 364 AGY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
A Y Y PT+ A + +D I +EE+FGPV +L FD +VI ++N +YGLA GI+
Sbjct: 362 ADYDRGAYYLPTILAGLENDDPICREEVFGPVLCVLPFDDEADVIAQSNANDYGLACGIW 421
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T + A + ++ + GTVW+N Y + PFGG KDSG+ RE G + + AY+ +K+V
Sbjct: 422 TRDFPKAWRTARAITTGTVWINTYKQFSISTPFGGEKDSGMDREKGREGIRAYMAQKSVY 481
Query: 480 ISLPKK 485
+ L K
Sbjct: 482 VDLTGK 487
>UniRef50_A0QP86 Cluster: Aldehyde dehydrogenase family protein;
n=14; Mycobacterium|Rep: Aldehyde dehydrogenase family
protein - Mycobacterium smegmatis (strain ATCC 700084 /
mc(2)155)
Length = 497
Score = 311 bits (763), Expect = 3e-83
Identities = 178/479 (37%), Positives = 258/479 (53%), Gaps = 11/479 (2%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
+ KLFI +WV+ E + FSP G + + F W
Sbjct: 18 WDKLFIGGQWVEPSSSEIIEVFSPATGEKVGQAPLATKADVDAACAAARKAFDEGP-WPR 76
Query: 67 ADASQRGKLLYKFADLIER---DFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
+R +L K LIE +F+ L KLE+ + + ++++ S A
Sbjct: 77 MTPQEREAVLAKATALIEESADEFKTLLKLETGQPQTIVD--MMQYGAAMSTLQFYASAA 134
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DK I + LK+PVGV G ++ WNVP + NK+ AL AGCT+V+KPA +
Sbjct: 135 DKFAWKDIRDGIYGQTLVLKEPVGVVGAVVAWNVPFFLAANKLGPALLAGCTIVLKPAAE 194
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT EAG+P+GV+++VPG G + G ALT +P + K +FTGS VGK I K
Sbjct: 195 TPLTTNLMAQKFLEAGLPEGVLSVVPG-GPETGRALTDNPALDKFTFTGSSAVGKEIGKI 253
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A LK TLELGGKS II+ DADL+ +P + GQ CV +R+ YD
Sbjct: 254 A-AEKLKPCTLELGGKSAAIILEDADLDSTLPMLLFSGLMNSGQACVGQTRILAPRSRYD 312
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG- 362
+ V+ A++VG P D + + GP I E +V G I+ G +EGA L+ GG R
Sbjct: 313 EVVEKVAAGVAAMQVGVPDDPAAMVGPLISEKQRERVEGYIKKGIEEGARLVTGGGRPEG 372
Query: 363 -TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
+G+++QPTVFADV++ MTIA+EEIFGPV ++ F+ ++ + AN++ YGLA ++TT
Sbjct: 373 LDSGWFVQPTVFADVDNSMTIAQEEIFGPVLVVIPFEDEDDAVRIANDSVYGLAGSVYTT 432
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ ++ + V GT +N Y APFGG+K+SGIGRE G + + Y E K+V++
Sbjct: 433 DHAKGVEIASKVRTGTYGINMY-AFDPGAPFGGYKNSGIGRECGPEGIAGYCESKSVLL 490
>UniRef50_Q4J873 Cluster: Aldehyde dehydrogenase; n=4;
Thermoprotei|Rep: Aldehyde dehydrogenase - Sulfolobus
acidocaldarius
Length = 481
Score = 311 bits (763), Expect = 3e-83
Identities = 169/424 (39%), Positives = 243/424 (57%), Gaps = 9/424 (2%)
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
+WR A +R K+L+K AD++E + +AK + + G + + +RY G L
Sbjct: 55 KWREYTAYERAKILFKTADILESRMQEIAKTLTMEEGKTLGESAYEVERVTSLLRYYGGL 114
Query: 123 ADKIQGDTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
G T+ + +S T+++P+GV G+I PWN P L+ K+ ALA G TVV KPA
Sbjct: 115 TLNSHGKTLQSSMKNSMHLTVREPIGVVGIITPWNFPFLIPGWKIAPALATGNTVVFKPA 174
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
TP EAG+P+GVVN+V G G + G + + ++ +SFTGSLEVG+ +
Sbjct: 175 SNTPTVAFELVNALYEAGLPEGVVNLVTGSGREVGDEIVTNKEIKAVSFTGSLEVGREVN 234
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
G N R+ LELGGK+ ++ + D NLAI + V + GQ+C+A SR V +
Sbjct: 235 SKIG-NRFTRLQLELGGKNATVLTKNGDFNLAIEHVTWSVMVNTGQVCLATSRFLVPKEL 293
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
+DK V E K++ VGN + GP KVLG +E GK EGA L+ GGE I
Sbjct: 294 HDKAVNAMTESFKSLVVGNALKQPVHMGPLSSRDQYEKVLGYVEIGKDEGAKLVYGGEPI 353
Query: 362 G----TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GY+++PT+F +V DM IAKEEIFGPV +I+ +++L+E I+ N+T+YGL A
Sbjct: 354 KGEDYDYGYFVKPTIFDNVTKDMRIAKEEIFGPVLAIMTYESLDEAIEIVNSTDYGLTAE 413
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQ-APFGGFKDSG--IGRENGIKAVEAYLE 474
I T NLN A++FS+ VEAG V VN Q P+GGFK SG + +E G +A++ Y +
Sbjct: 414 IVTNNLNEAMKFSEGVEAGVVKVNRPTVELDQWVPYGGFKGSGNDVYKELGEEALDFYTK 473
Query: 475 EKTV 478
K V
Sbjct: 474 IKAV 477
>UniRef50_A3IE80 Cluster: Aldehyde dehydrogenase; n=1; Bacillus sp.
B14905|Rep: Aldehyde dehydrogenase - Bacillus sp. B14905
Length = 484
Score = 310 bits (762), Expect = 4e-83
Identities = 173/476 (36%), Positives = 254/476 (53%), Gaps = 10/476 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+ I+ EW+ D +P G +IA+++ F+ + EWR A
Sbjct: 6 MLINGEWIYGDAEALLDVGNPSTGEIIAQISNASQAHVEEAVRSARRAFE-SDEWRQWKA 64
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+RG+LL FA I + E + LE D G + + G ADK+ GD
Sbjct: 65 FERGQLLIDFAHYIRQHAEEWSLLECRDVGKPLTQARADIEAAARYFEFYGGAADKVMGD 124
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
TIP + + + +PVG+ I+PWN PI + V A+A G V+VK AE TPLT
Sbjct: 125 TIPIEDGLLNAVVLEPVGITVHIVPWNYPIQITARSVAAAIATGNAVIVKSAEDTPLTTH 184
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
E +PKG+ + G G D G LT HPD+ I+FTGS+ G + KAA N+
Sbjct: 185 AITEWLAEK-LPKGIFQHITGLGRDVGPYLTSHPDINHITFTGSVPTGVAVMKAAA-ENV 242
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
VTLELGGKSP I+ DA++ A+ + + GQ C A +RL ++ I D F+
Sbjct: 243 VPVTLELGGKSPNIVFADANIEQALEGVVRAIIQNSGQTCSAGARLLIEESIKDTFLPQL 302
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY--- 366
V+ +AI+VG P + GP ++E K+ L++ KK+G ++ GGE + GY
Sbjct: 303 VQKFQAIQVG-PGEADMDMGPLLNERQYTKITTLLQQAKKDGY-VITGGEPLMMEGYENA 360
Query: 367 -YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y+QPT+ V + +A+EEIFGPV ++L F ++EE I AN+T+YGL AG+++ N++
Sbjct: 361 FYVQPTILDGVQPNDPLAQEEIFGPVLTVLTFTSVEEAITLANSTDYGLVAGVWSQNIDT 420
Query: 426 ALQFSKHVEAGTVWVNNY-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
A + V+AG V++NNY Q PFGG+K SGIGRE G A+ Y + K + I
Sbjct: 421 AHYVASRVQAGQVFINNYGAAGGIQMPFGGYKKSGIGREKGFVALRNYTQMKNIAI 476
>UniRef50_Q39MD0 Cluster: Aldehyde dehydrogenase; n=2;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 498
Score = 310 bits (761), Expect = 6e-83
Identities = 184/486 (37%), Positives = 269/486 (55%), Gaps = 18/486 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFID +W+D D FD +P V+ A F W
Sbjct: 17 RLFIDGQWLDWPDAR-FDQLNPCTNEVMTSFADAGAQGVELAVAAARKAFDEGP-WPRMR 74
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVY--KNCLRILSGIPDSV--RYLGSLAD 124
A R +LL + + E +A+L++ DNG+ Y R+ + V +LG + D
Sbjct: 75 AQDRKRLLQPIVERLYAAEEEIARLQTLDNGIPYAFSRHSRVSAKSAADVFDHFLGWI-D 133
Query: 125 KIQGDTIP--TDGDSFSY-TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
KI GDT+P + + Y T + PVGV +LP+N P+L F KV ALA GCTV+VK +
Sbjct: 134 KINGDTLPIFSGASNMQYMTFRDPVGVVAAVLPYNGPVLTFAMKVAPALACGCTVIVKSS 193
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E T L ++ +P GV N V G G + G ALT H V K++FTGS VG+ I
Sbjct: 194 ELTNLAVARLAQIIADSDLPPGVFNFVTG-GVETGSALTSHAGVDKVTFTGSPAVGEKIM 252
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVF--FHQGQICVAASRLYVQS 299
A+ +KR++LELGGKS ++ D +A G+ F GQ+C SR V
Sbjct: 253 IASAPT-MKRLSLELGGKSAALVFPDTRSVQTTAHALMGLCSTFLSGQVCSTPSRAVVHR 311
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
I D+F+ A E + +R G+PFD +T + P I +VL +E+G+++GA LLAGG
Sbjct: 312 SIMDEFLHHAQEQLQKVRFGDPFDAATTSAPMISRRHQARVLDYVESGRQQGATLLAGGR 371
Query: 360 RIGTA---GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
G G +++P +FA+V++DMTIA+EEIFGPV S++ FDT EE I AN++ YGLA
Sbjct: 372 APGGEFRNGNWVEPALFANVSNDMTIAQEEIFGPVLSVIPFDTEEEAIRIANDSAYGLAG 431
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
++TT+++ A + ++ V++G + VN + ++ + APFGG K SG GRE G +EA+ E K
Sbjct: 432 CVYTTDVSRAFRVARAVKSGAIGVNGFASIPN-APFGGIKRSGTGREGGWSTIEAFTELK 490
Query: 477 TVIISL 482
TV +L
Sbjct: 491 TVNFNL 496
>UniRef50_A3VCB8 Cluster: Aldehyde dehydrogenase family protein;
n=2; unclassified Rhodobacterales|Rep: Aldehyde
dehydrogenase family protein - Rhodobacterales bacterium
HTCC2654
Length = 494
Score = 310 bits (761), Expect = 6e-83
Identities = 181/476 (38%), Positives = 257/476 (53%), Gaps = 8/476 (1%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
ID E A DG D SP +G V+ + +G F+ + W +
Sbjct: 22 IDGERRGASDGGEMDVISPLNGKVLTTIPRGTRVDAERAIASARRAFE-DGRWAELPPAA 80
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI--LSGIPDSVRYLGSLADKIQGD 129
R + L K+ADLIE + LA L DNG + LS + ++RY DK+ G+
Sbjct: 81 RKRTLLKWADLIEANALELAVLGVRDNGTEIGMAFKAEPLSAVA-TIRYYAEAIDKLYGE 139
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
PTD + + PVGV G I+PWN P+++ KV ALAAG +VV+KPAE LT
Sbjct: 140 IAPTDPSVLALVHRAPVGVVGAIVPWNFPLMIGAWKVAPALAAGNSVVLKPAETASLTLL 199
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAGIP GV N+V G G G A+ DV + FTGS VG+ + + + +NL
Sbjct: 200 RIAELALEAGIPPGVFNVVTGEGAVVGEAMGLSMDVDVLVFTGSGPVGRRLLEYSAKSNL 259
Query: 250 KRVTLELGGKSPLIIMNDA-DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
KRV LELGGKSP I+ DA DL A+ + +G+F + GQ+CVA SRL V+ I+D+FV
Sbjct: 260 KRVYLELGGKSPNIVFADAPDLTEAVKVSANGIFRNAGQVCVAGSRLLVERAIHDEFVSK 319
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI--GTAGY 366
E+ K + VGNP D ST G +++ L ++ + G ++ GG RI T GY
Sbjct: 320 LAEFVKTMSVGNPLDLSTSAGAVNSLRQLDQNLRFVDEARSAG-RVVIGGARILEETGGY 378
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+++PT+ V+ IA+ E+FGPV +++ FD+ E + AN T+YGLAA ++T +L+ A
Sbjct: 379 FMEPTIVTGVDPSDPIAQNEVFGPVVAVIPFDSEGEAVRIANGTDYGLAAAVWTRDLSRA 438
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ + + AG V VN Y P GG K SG G + + A + YL+ KT I L
Sbjct: 439 HRMIRAIRAGVVHVNTYGGPDVTVPIGGVKQSGNGHDKSLHAFDKYLDLKTAWIKL 494
>UniRef50_Q4STS4 Cluster: Chromosome undetermined SCAF14118, whole
genome shotgun sequence; n=2; Bilateria|Rep: Chromosome
undetermined SCAF14118, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 787
Score = 309 bits (759), Expect = 1e-82
Identities = 154/324 (47%), Positives = 200/324 (61%), Gaps = 1/324 (0%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
+ ++FIDN+WV + +TF TF+P G I V + QR S WR
Sbjct: 1 FLQIFIDNKWVPSSRRKTFPTFNPATGCKICDVEEADQEDVDQAVMAAKAAGQRGSPWRR 60
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADK 125
DA RGKLL++ ADL+ERD LA LE+ D G + I L G ++RY DK
Sbjct: 61 MDACSRGKLLHQLADLVERDRLLLATLETLDTGKPFLQSFFIDLEGSIKTLRYYAGWTDK 120
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
I G ++ D T +PVGVCG I+PWN P+LMF+ K+ AL+ G TVV+KPAEQTP
Sbjct: 121 IHGKSLRVDESFMCITKHEPVGVCGAIIPWNFPLLMFMWKIAPALSCGNTVVIKPAEQTP 180
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G+LIQ AA
Sbjct: 181 LTALHIGSLIKEAGFPAGVVNIVPGFGPTAGAAIASHMDVDKVAFTGSTEIGQLIQTAAA 240
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLKRVTLELGGK+P I+ D DL LA+ G F++QGQ C AASR++V+ I+++F
Sbjct: 241 KSNLKRVTLELGGKNPCIVFADCDLQLAVEETQKGAFYNQGQCCTAASRVFVEESIHEEF 300
Query: 306 VKGAVEYAKAIRVGNPFDESTVNG 329
V ++E AK I +G+P D T +G
Sbjct: 301 VHLSIEKAKKIVIGDPLDPLTSHG 324
>UniRef50_Q6SF25 Cluster: Aldehyde dehydrogenase family protein;
n=6; Bacteria|Rep: Aldehyde dehydrogenase family protein
- uncultured bacterium 582
Length = 485
Score = 309 bits (759), Expect = 1e-82
Identities = 174/487 (35%), Positives = 255/487 (52%), Gaps = 11/487 (2%)
Query: 4 EIK-YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
E+K Y + +ID WVD G D +P G IA+ A +S
Sbjct: 3 EVKGYWQNYIDGAWVDGGAGR-IDVINPGTGEKIAEQALADARDVDLAVQAAKRV---HS 58
Query: 63 EWRLADAS--QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLG 120
L D +RG+++ + E +A L S + G ++G Y G
Sbjct: 59 TGVLTDMRPVERGRIVQAMGRYLLEHLEEIAALLSLEQGKPIWEARIEVTGAARYFEYYG 118
Query: 121 SLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
+ A+ ++G +IP F +T +P GV I+PWN P+ M + AL G TVVVKP
Sbjct: 119 NQAETLEGRSIPLGAGYFDFTTDEPYGVSAQIIPWNFPVEMTARSLSAALTTGNTVVVKP 178
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
E TPL+ + G+PKG VN+V G+G AG AL+ HPD+ ++ FTGS+ G I
Sbjct: 179 PEMTPLSNAWFAHAAEAVGLPKGAVNLVCGYGHQAGAALSAHPDINQVVFTGSVATGIAI 238
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
AA N + V LELGGKS I+ +DADL G+F + GQ+C A SR+ V
Sbjct: 239 ASAAAKNVVPCV-LELGGKSAAIVHSDADLVAMETDIRKGIFINAGQVCSAMSRIIVHES 297
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVN---GPQIDESMMNKVLGLIETGKKEGANLLAG 357
+D+ V+ AV A+++ VG D T GP + ++ GL+ +GA L+ G
Sbjct: 298 RHDELVQRAVSIAESLSVGPGADRQTFGANMGPMVSVKQRDRAAGLVSEAVSQGAKLVTG 357
Query: 358 GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G + G ++QPTV A+V +MTIA+ E+FGPV S+L+F E I+ AN T+YGL G
Sbjct: 358 GRAMNIPGAFLQPTVLAEVTPEMTIAQTEVFGPVLSVLRFREDAEAIEIANGTDYGLVGG 417
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT +L+ A Q ++ + AG V+VN + + PFGG+ SG GRE G +A+ Y++ K
Sbjct: 418 VFTRDLDRATQVARKIRAGQVFVNEWFAGGVETPFGGYGKSGYGREKGREALWNYVQTKN 477
Query: 478 VIISLPK 484
+ I L +
Sbjct: 478 IAIKLKR 484
>UniRef50_A1G3Y3 Cluster: Aldehyde dehydrogenase; n=4; Bacteria|Rep:
Aldehyde dehydrogenase - Salinispora arenicola CNS205
Length = 753
Score = 309 bits (759), Expect = 1e-82
Identities = 177/466 (37%), Positives = 255/466 (54%), Gaps = 15/466 (3%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LF+ ++VD DG TF T +P V+A++A+ ++R W
Sbjct: 299 LFVGGDFVDPTDGGTFKTINPASEEVLAEIAEASAGDVDRAVRAARSAYERI--WAPMPG 356
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQG 128
R K L++ A +I+ LA LES DNG K + L + Y ADK+
Sbjct: 357 RDRAKYLFRIARIIQERSRELAVLESLDNGKPIKESRDVDLPLVAAHFFYYAGWADKL-- 414
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
D F +P+GV ++PWN P+LM K+ ALAAG TVV+KPAE TPLT
Sbjct: 415 -----DHAGFGPG-PRPLGVAAQVIPWNFPLLMLAWKIAPALAAGNTVVLKPAETTPLTA 468
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA-AGTN 247
++A +P GVVN+V G G D G AL H DV K++FTGS VG+ I +A AGT
Sbjct: 469 LLFAEICQQADLPGGVVNVVTGAG-DTGRALVEHHDVDKVAFTGSTAVGRAIARAVAGTE 527
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
K++TLELGGK+ I+ +DA ++ A+ +G+FF+QG +C A SRL +Q + D+ +
Sbjct: 528 --KKLTLELGGKAANIVFDDAAVDQAVEGIVNGIFFNQGHVCCAGSRLLLQESVADQVMA 585
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
+RVG+P D++T G + + ++ L +TG EGA + + G++
Sbjct: 586 SLKRRMAQLRVGDPLDKNTDIGAINSAAQLARIRELSDTGAAEGAERWSPPCELPDRGFW 645
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
PTVF V IA+EEIFGPV S+L F T E +++ANNT YGL+AG++T + L
Sbjct: 646 FAPTVFTGVTQAHRIAREEIFGPVLSVLTFRTPAEAVEKANNTPYGLSAGVWTEKGSRML 705
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
+ + AG VW N + +PFGG+++SG GRE G +EAYL
Sbjct: 706 WMADRLRAGVVWANTFNRFDPTSPFGGYQESGYGREGGRHGLEAYL 751
>UniRef50_Q39HU8 Cluster: Aldehyde dehydrogenase; n=2;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 483
Score = 309 bits (758), Expect = 1e-82
Identities = 172/479 (35%), Positives = 262/479 (54%), Gaps = 9/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L ID E VD++ GE + +P +VI + G + W
Sbjct: 9 RLLIDGELVDSETGEWAASINPATEAVIGRAPAGSRRDVARAVDAAQRAWPA---WAERT 65
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+RG+LL F + + E L+++E D+G Y L + S+RY L + G
Sbjct: 66 GEERGELLRGFGERLLERAEELSRIEVLDSGNTYVPTLASMHETVRSLRYYAGLVHGLHG 125
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
+TIP G + T+ +P GV G I +N P + + +AL G TVVVKP E +PL+
Sbjct: 126 ETIPATGRNLHMTVYEPYGVVGRIAAFNHPAMFSAARTASALVTGNTVVVKPPETSPLSV 185
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
++ +P GV NIV G G + G AL HPDV +++ GS+ G+ IQ++A
Sbjct: 186 LVLGEVARDT-LPAGVFNIVNGTGAEVGDALVRHPDVKRLALIGSVATGQAIQRSAAEVG 244
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFH-QGQICVAASRLYVQSGIYDKFVK 307
+K VTLELGGK+P+I+ DAD + A A G+ F QGQ C + SRL V IYD +
Sbjct: 245 VKHVTLELGGKNPMIVFPDADPDAAADSAVRGMNFSWQGQSCGSNSRLLVHDDIYDDVLA 304
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI-GTA-- 364
VE AIRVG+P T GP + V+ ++ + GA L+ GG R G A
Sbjct: 305 RVVERVAAIRVGDPMSPDTGMGPINSRKSYDHVMSFLDPAQTHGARLMTGGRRPPGHAFE 364
Query: 365 -GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G++++PTV+ADV M + +EE+FGP+ S+ ++ ++EV+ AN+T YGL+A I+T ++
Sbjct: 365 KGFWVEPTVYADVTPGMRLWREEVFGPILSVARWRDVDEVVAMANDTEYGLSAAIWTNDI 424
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
AL ++ + AG+V+VN T P+GGFK+SG+ RE GI+ + +Y+E+K + + L
Sbjct: 425 RQALNTARRIRAGSVFVNGSNTHFLGVPWGGFKNSGVDREEGIEEMYSYVEKKVINVML 483
>UniRef50_Q11AU6 Cluster: Aldehyde dehydrogenase; n=22;
Bacteria|Rep: Aldehyde dehydrogenase - Mesorhizobium sp.
(strain BNC1)
Length = 493
Score = 309 bits (758), Expect = 1e-82
Identities = 167/478 (34%), Positives = 252/478 (52%), Gaps = 6/478 (1%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+ + LFI W + G + P G+VIA+VA +
Sbjct: 16 PKALRSNLFIGGAWKEGATGNRIPVYDPSTGTVIAEVADAEVEDVMGAIDAAHEALPG-- 73
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
W R ++L + +L+ + + LA+L S +NG + ++ + R+
Sbjct: 74 -WAATPPRHRSEVLRRCFELMIENRDMLAELISLENGKTLADAQGEVAYAAEFFRWFAEE 132
Query: 123 ADKIQGDTIPT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
++ G+ G + QP+GV L+ PWN P M K+ ALAAGCTV++KPA
Sbjct: 133 TVRLNGELYKAPSGANRILVQHQPIGVSVLVTPWNFPAAMATRKIGPALAAGCTVILKPA 192
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGV-ALTHHPDVAKISFTGSLEVGKLI 240
+TPLT EAG+P GVVN+ V A+ H P V K+SFTGS EVG+++
Sbjct: 193 TETPLTAYALAALCAEAGVPDGVVNVYTSSRSGKTVSAMLHDPRVRKLSFTGSTEVGRIL 252
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
+ A + ++ELGG +P I+ +DADL+ A+ A + G+ C AA+R YVQSG
Sbjct: 253 LREAADKVIS-CSMELGGNAPFIVFDDADLSAALDGAMVAKMRNGGEACTAANRFYVQSG 311
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
I D F KG E KA+ +G ++ + GP I++ + ++ GL+E + GA +LAGG+
Sbjct: 312 IADAFAKGLAERMKALAIGKGYETGSQCGPLINKDAVERISGLVEEAQSRGARVLAGGKA 371
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
+ GYY PTV +V+ I EEIFGPV I++FD+ +EV+ AN T YGL A ++T
Sbjct: 372 LNREGYYFPPTVIDNVDPASAIMSEEIFGPVAPIIRFDSEDEVLSAANGTEYGLMAYVYT 431
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+L+ L+ S+ +E+G V +N L APFGG K SG+GRE + + E K +
Sbjct: 432 QDLSKGLRVSEKIESGMVGLNRGLVSDPAAPFGGVKQSGLGREGSHHGILEFTETKYI 489
>UniRef50_A3Q4A6 Cluster: Aldehyde dehydrogenase; n=1; Mycobacterium
sp. JLS|Rep: Aldehyde dehydrogenase - Mycobacterium sp.
(strain JLS)
Length = 497
Score = 309 bits (758), Expect = 1e-82
Identities = 173/480 (36%), Positives = 260/480 (54%), Gaps = 10/480 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
++ I + V A DG T + +PHDGS IA+V F +WR
Sbjct: 21 RMLIGGDRVAAGDGATMEITAPHDGSTIARVPAASPADVDAAVAAAAAAFP---QWRATT 77
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+R +++ FA + L++ D G + + + Y ++A I G
Sbjct: 78 LLERAEMIRSFAQRLRSRATDFGLLDAVDTGNPVTAMIGDVMMAARWLDYHAAVAFSITG 137
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
DT+P+ S+ T K+P G I+P+N PIL KV L G T+V+K +Q PL+
Sbjct: 138 DTLPSMTRSWLMTRKEPYGAVARIIPYNHPILFAAAKVGAPLITGNTLVLKVPDQAPLSS 197
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
E+ P GVVNI+ G G AG AL H DV +I+ GS+ G+ + AA
Sbjct: 198 LLMAEVVLES-FPPGVVNIISGSGAVAGDALVRHRDVKRIALIGSVPTGQKVMAAAAEAG 256
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFH--QGQICVAASRLYVQSGIYDKFV 306
+K VTLELGGK+ +I+ DAD + + A G+ H QGQ C + +RL++ ++D+ V
Sbjct: 257 IKHVTLELGGKNAMIVCPDADPSAVVEGAAFGMNCHWSQGQSCGSTTRLFLHESLHDQVV 316
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG---- 362
G VE K+IR+G+P D +T G + E+ +KV I+ K+EGA L+ GG R
Sbjct: 317 SGLVERLKSIRIGHPLDPATEMGCLVSEAQFDKVNHYIDVAKREGARLVTGGGRPPGKEF 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
AG+Y++PTVFADV+ MT+A+EEIFGPV S+L+F L+ + +AN GL I++ +
Sbjct: 377 EAGFYVEPTVFADVDMSMTVAREEIFGPVLSVLRFTDLDAAVAQANELPLGLTGAIWSND 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ A+ + ++ G VW+N + APFGG K+SG G E G++ +E+YL+ KTV I L
Sbjct: 437 ITTAVSVADRLDTGYVWINGSGSHFLGAPFGGHKNSGTGTEEGVEELESYLQTKTVNIPL 496
>UniRef50_Q98LH9 Cluster: Aldehyde dehydrogenase; n=1; Mesorhizobium
loti|Rep: Aldehyde dehydrogenase - Rhizobium loti
(Mesorhizobium loti)
Length = 495
Score = 308 bits (757), Expect = 2e-82
Identities = 172/472 (36%), Positives = 258/472 (54%), Gaps = 4/472 (0%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI +VD + + SP G ++A+ A G F+ + W
Sbjct: 15 FIGGRFVDGSGSGSIERRSPATGDLVARYADGTPEDVDLAVEAARIAFE-DGPWPRMSGM 73
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADLI + + L ++E + G + + G RY SLA ++ G T
Sbjct: 74 ERAEVLNRLADLIRTNRDRLVRIEVEEVGKPVRFARGDIDGAAGLTRYAASLAMQMAGLT 133
Query: 131 IPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
GD + + ++ VGV L+ PWN P L+ KV ALAAGCTVV+KP+E TP +
Sbjct: 134 YTNIGDGKTALISREAVGVVALVTPWNFPALILSQKVPFALAAGCTVVLKPSEFTPGSAF 193
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAG+P G N+V G+G AG LT H + +SFTGS G + + +L
Sbjct: 194 EIAALAAEAGVPAGAFNVVSGYGATAGDHLTGHMGIDFVSFTGSTRTGSRVVGNT-SRHL 252
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
+ ++ELGGKS I+ DADL A A GVFF+ G+ CV+ SRL+VQS I D F+
Sbjct: 253 VKSSVELGGKSANIVFADADLEAAADGALMGVFFNNGECCVSGSRLFVQSSIADDFIAKV 312
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE-RIGTAGYYI 368
+ ++ ++VG+PFD+ T G ID + + KV G +++G +EGA L+ GG G G++
Sbjct: 313 IARSRKMKVGDPFDDDTDVGALIDRNHLAKVTGFVKSGIEEGAQLVLGGNVAAGAVGHFH 372
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
+ T+F V MTI +EEIFGPV SI +FDT+++ + AN+T YGL+ I++ N++ L
Sbjct: 373 EATIFDRVEPHMTIFREEIFGPVLSITRFDTVDDAVRLANDTAYGLSNYIWSKNIDTVLT 432
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+K +++G V N + A Q P G K SG G E G E + + KT++I
Sbjct: 433 VAKRLKSGWVQANTIIDGAPQLPLTGVKGSGFGYEMGQAGFEEFTQLKTLLI 484
>UniRef50_Q02AF5 Cluster: Aldehyde dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Aldehyde dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 478
Score = 308 bits (757), Expect = 2e-82
Identities = 175/478 (36%), Positives = 255/478 (53%), Gaps = 14/478 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSP-HDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+I+ EW+ A G TF+ +P + V+A +AKG F W
Sbjct: 5 YINGEWIAA--GATFENRNPANTDEVVAVMAKGSAADIAAAADAAGAAFPA---WSAMSG 59
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
RG +LYK AD++++ F+ +A + + G + + +RY ++ G
Sbjct: 60 PARGNILYKAADILDKTFDSVAADMTREEGKTLPEAKGEVRRAINILRYFAGEGSRLPGM 119
Query: 130 TIPTDGDSFS-YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
+P++ D + L++PVGV GLI PWN P + K+ AL G TVV+KPA PL+
Sbjct: 120 LVPSERDRVHMFALRKPVGVVGLITPWNFPSAIPAWKLAPALICGNTVVIKPASAAPLSA 179
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+AGIPKGVVN + G G + G AL + + +SFTGS E+G + A
Sbjct: 180 WRIVEALHQAGIPKGVVNFIAGSGGELGQALVNAAPLKAVSFTGSCEIGDWLHAEASKRR 239
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
L R+ LE+GGK+P I++ DAD A+ + FF GQ C A SR V+ IYDKFV
Sbjct: 240 L-RIQLEMGGKNPTIVLADADFGSAVENVVNAAFFSTGQKCTATSRAIVEDAIYDKFVAA 298
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG----TA 364
V + ++VG+ GP +D+S M VL IE G+KE GG+R+
Sbjct: 299 VVARTRKLKVGDGMQPGIDIGPCVDQSQMETVLRYIEIGRKECGEPACGGKRLTEGALAK 358
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GY+++PTVFA V D TIA+EEIFGPV +I++ E+ + AN+ +GL++ I TTNL+
Sbjct: 359 GYFVEPTVFAGVTPDQTIAREEIFGPVLAIMRARDFEDAMSIANSIPFGLSSSIQTTNLS 418
Query: 425 NALQFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGIG-RENGIKAVEAYLEEKTVII 480
A ++ EAG + VN + +Q PFGG KDS G +E G A+E Y + KTV +
Sbjct: 419 RAFEYIYRAEAGLLTVNLPSAGVEYQLPFGGTKDSSFGPKEQGPAALEFYSDYKTVYL 476
>UniRef50_P25526 Cluster: Succinate-semialdehyde dehydrogenase
[NADP+]; n=108; cellular organisms|Rep:
Succinate-semialdehyde dehydrogenase [NADP+] -
Escherichia coli (strain K12)
Length = 482
Score = 308 bits (757), Expect = 2e-82
Identities = 166/472 (35%), Positives = 246/472 (52%), Gaps = 5/472 (1%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
I+ EW+DA +GE D +P +G + V K WR A +
Sbjct: 15 INGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPA---WRALTAKE 71
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTI 131
R +L + +L+ + LA+L + + G +S + + +I GDTI
Sbjct: 72 RATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTI 131
Query: 132 PT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
P D +KQP+GV I PWN P M K ALAAGCT+V+KPA QTP +
Sbjct: 132 PGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALA 191
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
AG+P GV N+V G G LT +P V K+SFTGS E+G+ + + ++K
Sbjct: 192 LAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCA-KDIK 250
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
+V+LELGG +P I+ +DADL+ A+ A + F + GQ CV A+RLYVQ G+YD+F +
Sbjct: 251 KVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQ 310
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ + +G+ D GP IDE + KV I ++GA ++ GG+ G + QP
Sbjct: 311 QAVSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQP 370
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
T+ DV + ++KEE FGP+ + +F +VI +AN+T +GLAA + +L+ +
Sbjct: 371 TILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVG 430
Query: 431 KHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ +E G V +N + APFGG K SG+GRE +E YLE K + I L
Sbjct: 431 EALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCIGL 482
>UniRef50_Q40024 Cluster: Betaine aldehyde dehydrogenase; n=60;
Magnoliophyta|Rep: Betaine aldehyde dehydrogenase -
Hordeum vulgare (Barley)
Length = 505
Score = 308 bits (756), Expect = 2e-82
Identities = 180/485 (37%), Positives = 251/485 (51%), Gaps = 11/485 (2%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P I LFI W + G +P I + R
Sbjct: 5 PAIPRRGLFIGGGWREPTLGRHIPVINPATEDTIGDIPAATAEDVELAVAAGGPVLARRR 64
Query: 63 E-WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGS 121
E W A + R K L A I YLA LE+ D+G + + + Y +
Sbjct: 65 EPWARASGATRAKYLNAIAAKITGKIAYLALLETVDSGKPKDEAVADMDDVAACFEYYAA 124
Query: 122 LADKIQGDT---IPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
LA+ + G I + F +Y LK+P+GV GLI PWN P+LM KV ALAAGCT V
Sbjct: 125 LAEALDGKQHAPISLPMEEFKTYVLKEPIGVVGLITPWNYPLLMATWKVAPALAAGCTAV 184
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
+KP+E LT +E G+P GV+NI+ G G DAG + HP V KI+FTGS G
Sbjct: 185 LKPSELASLTCLELGAICEEIGLPSGVLNIITGLGPDAGAPIASHPHVDKIAFTGSTATG 244
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMND-ADLNLAIPYAGSGVFFHQGQICVAASRLY 296
K I AA +K V+LELGGKSPL+ +D AD++ A+ + G FF+ GQ+C A SRL
Sbjct: 245 KTIMTAA-AQMVKPVSLELGGKSPLVTFDDVADIDKAVEWPMLGCFFNGGQVCSATSRLL 303
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
+ I + F+ VE+AK I++ +P +E G I + ++ I T + EGA +L
Sbjct: 304 LHEKIAEPFLDRLVEWAKNIKISDPLEEGCRLGSVISKGQYEQIKKFISTARSEGATILH 363
Query: 357 GGER---IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYG 413
GG+R +G G++I+PT+ V+ M I +EE+FGPV + F T E ++ AN+T+YG
Sbjct: 364 GGDRPKHLG-KGFFIEPTINTGVSTSMQIWREEVFGPVICVKVFKTESEAVELANDTHYG 422
Query: 414 LAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
LA G+ + +L + +K + +G VW N QAP+GG K SG GRE G +E YL
Sbjct: 423 LAGGVISDDLERCERIAKVIHSGIVWKNCSQPTLVQAPWGGNKRSGFGRELGEWGLENYL 482
Query: 474 EEKTV 478
K V
Sbjct: 483 SVKQV 487
>UniRef50_Q0S070 Cluster: Aldehyde dehydrogenase; n=10;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 493
Score = 308 bits (755), Expect = 3e-82
Identities = 171/477 (35%), Positives = 253/477 (53%), Gaps = 6/477 (1%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
I YT LFI +WV T S VI V +G F + W
Sbjct: 15 ISYTSLFIGGQWVAPSTAATISVTSASTEEVIGVVPEGAPADADAAVAAARRAFDDPTGW 74
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVR--YLGSL 122
+ S+R + L K A I E + +L S NGM + G P ++ Y G +
Sbjct: 75 ASLEPSRRAETLEKLAAAIGESSEDIVRLVSEQNGMPISTARAVEGGFPGALLRLYAGMV 134
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
D+ + P +QPVGV I+PWN P + +K+ ALAAGCTVV+KP+
Sbjct: 135 RDQQLEEERPGMFGGHVVVRRQPVGVVAAIVPWNFPQTLLFSKLAPALAAGCTVVIKPSP 194
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
+T L ++AG+P GVVNIVPG G + G L HP V K++FTGS G+ I +
Sbjct: 195 ETVLDVFRLAELLEQAGLPHGVVNIVPG-GRELGAYLVEHPGVDKVAFTGSTPAGRSIAE 253
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A G L+ VTLELGGKS I+++DA+L + + GQ C +R+ Y
Sbjct: 254 ACG-RLLRPVTLELGGKSAAIVLDDAELVSSAQDLFGATLLNNGQTCFVGTRILAPRSRY 312
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+ V + A + VG+ DE+T+ GP + ++V G I GK EGA L GG R
Sbjct: 313 DEVVDVFTQMAASAVVGDALDEATMVGPMASSTHRDRVEGYIAQGKSEGARLTTGGGRPE 372
Query: 363 T-AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G+++QPT+FADV++ TIA+EEIFGPV SI+ + +++ + AN++ YGL +++
Sbjct: 373 RDRGWFVQPTIFADVDNSATIAREEIFGPVLSIIPYGDIDDAVHIANDSGYGLGGTVWSQ 432
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+L +A ++ V+ GTV +N+Y+ APFGG K SG+GRE G + + Y +++++
Sbjct: 433 DLEHAGAVARRVQTGTVGINHYIP-DPAAPFGGVKGSGLGREFGPEGLANYQQQQSI 488
>UniRef50_Q0RW45 Cluster: Possible aldehyde dehydrogenase; n=3;
Actinomycetales|Rep: Possible aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 495
Score = 308 bits (755), Expect = 3e-82
Identities = 176/425 (41%), Positives = 242/425 (56%), Gaps = 11/425 (2%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
WR +R +LL K ADL+E + + + D GM Y L +L P RY A
Sbjct: 68 WRRTPGPERRRLLLKLADLLEANGPEFGRRTTIDMGMNYVPHLGMLGEWP---RYYAGWA 124
Query: 124 DKIQGDT--IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
DKI D + G FSYT+ +P GV G+I+ WN P+ K+ ALAAG TVVVKP
Sbjct: 125 DKIVSDVTGLGASGGEFSYTIAEPYGVIGVIITWNGPVGSMCMKLPPALAAGNTVVVKPP 184
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E P KEAG P GV+NIVPG G +AG AL HP V KISFTG K I
Sbjct: 185 ELAPYGPELFAELVKEAGFPPGVINIVPG-GREAGEALVTHPLVQKISFTGGPATAKAIL 243
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAG-SGVFFHQGQICVAASRLYVQSG 300
++ +K LELGGKS +I DADL+ A +A V F GQ C +R+ VQ
Sbjct: 244 RSTA-ETMKPTLLELGGKSANLIFEDADLDSACTHAAVMSVGFLAGQGCAFPTRMLVQDT 302
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
IY+ V+ + VG+PFD T GP ++++ ++++LG IE K++GA L+ GG+R
Sbjct: 303 IYEDVVQRIEKIVSGFVVGDPFDPRTTTGPVVNQAAVDRILGFIEGAKRDGARLVIGGKR 362
Query: 361 IG---TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G G +I+PTVFADV+ D +A+ E+FGPV SI+KF T +E I+ AN T Y LAA
Sbjct: 363 AGGELAQGCFIEPTVFADVDPDSELAQGEVFGPVLSIIKFSTEDEAIEIANGTPYALAAY 422
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
I T+++ A + ++ + AGT+ +N +A PFGGF SG G+E G ++ +L K+
Sbjct: 423 IRTSDVTRAHRVAEQLVAGTISINGASNLAADKPFGGFNLSGTGKEGGKAGLDEFLRIKS 482
Query: 478 VIISL 482
V + +
Sbjct: 483 VGVGM 487
>UniRef50_Q0ETU5 Cluster: Aldehyde dehydrogenase; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Aldehyde
dehydrogenase - Thermoanaerobacter ethanolicus X514
Length = 484
Score = 307 bits (753), Expect = 5e-82
Identities = 165/482 (34%), Positives = 267/482 (55%), Gaps = 9/482 (1%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
+++ K+ I +WVDAK G + +P V A V F + W
Sbjct: 2 VQHYKMLIGGKWVDAKKGGIIEVVNPATEEVFASVPAATKEDVEEAILKAQEAFLK---W 58
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
+ + QR K+L K ++++ + E +A+ + + G K + + +RY +
Sbjct: 59 KKENPFQRSKILRKASEIVLQRSEKIARTMTEELGKPVKEAKGEVEKGAEILRYYAEEGE 118
Query: 125 KIQGDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+I G I + D+ S + +P+GV I PWN PI + K+ ALA+GCT+V K +
Sbjct: 119 RIYGRVIANEEKDTESIVVYEPIGVAAAITPWNYPIELLAWKIGGALASGCTIVAKLPSE 178
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPL+ +AG+P+GV+N++ G G G AL +P V +++FTGS E GK I K
Sbjct: 179 TPLSPLKFVECLVDAGVPEGVLNVITGSGGTVGPALIENPLVKRVAFTGSTETGKEILKM 238
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ ++ +K+VTLELGG P+I+ DA+L+ A+ A F + GQIC+A +R+YV+ +Y+
Sbjct: 239 SASSGIKKVTLELGGSLPMIVFKDANLDAAVTGAVRRSFRNAGQICIAVNRIYVEREVYE 298
Query: 304 KFVKGAVEYAKAIRVGNP-FDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
F++ K + VGN DE+ GP ++ + KV + +GA ++ GG+R
Sbjct: 299 TFLEKFGAKTKKLVVGNSLIDENVDMGPMCTKAGVEKVERHVNDAVAKGAKIVCGGKRPS 358
Query: 363 ----TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
G++ +PT+ DVN DM I +EE FGP ++ F+ ++E I AN+TNYGLAA +
Sbjct: 359 GPKFEKGFFYEPTIVRDVNHDMLIMREETFGPAVGVMPFNNIDEAIQLANDTNYGLAAIV 418
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+T N+N A + ++ ++AG V +NN AP+GG+KDSG+G E+G + + YL +K V
Sbjct: 419 YTNNMNIAKRCAQEIQAGNVAINNVDAGVINAPYGGWKDSGLGAEHGPEGLHEYLIQKHV 478
Query: 479 II 480
I
Sbjct: 479 RI 480
>UniRef50_Q395Z7 Cluster: Succinate-semialdehyde dehydrogenase
(NAD(P)+); n=40; Proteobacteria|Rep:
Succinate-semialdehyde dehydrogenase (NAD(P)+) -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 481
Score = 306 bits (752), Expect = 7e-82
Identities = 162/474 (34%), Positives = 245/474 (51%), Gaps = 5/474 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T+L ID EWVDA G+T D +P G I KVA F WR
Sbjct: 9 TQLLIDGEWVDAASGKTIDVVNPATGKPIGKVAHAGIADLDRALAAAQRGFDA---WRKV 65
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R + K A L+ + +A+L + + G + D + + ++
Sbjct: 66 PAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEARVEVLSAADIIEWFADEGRRVY 125
Query: 128 GDTIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G +P T+ K+PVG PWN P+ + K+ ALA GC+ +VK E+TP
Sbjct: 126 GRIVPPRNLGAQQTVVKEPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLVKAPEETPA 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ +AG+P GV+ +V G + L HP + K++FTGS VGK + AG
Sbjct: 186 SPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQLAAMAGL 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ +KR T+ELGG +P+I+ DAD+ LA+ AG F + GQ+C++ +R V + I D+F
Sbjct: 246 H-MKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVHNSIRDEFT 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ V++A+ ++VGN +E T G + + + +++ +K GA + GGERIGT G
Sbjct: 305 RALVKHAEGLKVGNGLEEGTALGALANPRRLTAMASVVDNARKVGARIETGGERIGTEGN 364
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ PTV ADV + + E FGPV +I FD L++ I AN +GLA FT + N
Sbjct: 365 FFAPTVIADVPLEADVFNNEPFGPVAAIRGFDKLDDAIAEANRLPFGLAGYAFTRSFANV 424
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++ +E G +W+N T + PFGG KDSG G E G +A+E YL K+V +
Sbjct: 425 HLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSVTV 478
>UniRef50_Q4J7R8 Cluster: Aldehyde dehydrogenase; n=2;
Thermoprotei|Rep: Aldehyde dehydrogenase - Sulfolobus
acidocaldarius
Length = 481
Score = 306 bits (752), Expect = 7e-82
Identities = 171/464 (36%), Positives = 254/464 (54%), Gaps = 12/464 (2%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
++Y KLFI+ E+ + GE SP D S +A++A G F+ W
Sbjct: 3 VRY-KLFINGEFSEPHSGEYKVKTSPIDNSPLAEIAVGDREDAKRAIDSAYEAFKG---W 58
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
A +R + L K + I + L + G YK + VR +A
Sbjct: 59 SSLTAMKRSEYLLKLEETIRANEGDLINTLIVEGGGTYKKAWGEVVFTERLVRNAAEMAR 118
Query: 125 KIQGDTIPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+G+TIP+D + S T ++P GV G I PWN P+ + + KV +LA G TVV+K + +
Sbjct: 119 HFKGETIPSDSEGIISMTFRKPKGVVGAITPWNYPLSISMKKVAHSLAIGNTVVLKLSSE 178
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP+ + AG+PKGVVN+V G G G + + V+ ++FTG G+ I
Sbjct: 179 TPIIGVKIAELVQRAGLPKGVVNVVTGPGSAVGDEIVTNKRVSHVTFTGETNTGREIASK 238
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
AG ++LK VTLELGG PLI+++DAD+NLA+ A G FFHQGQIC ++ R+ V +Y+
Sbjct: 239 AG-HSLKTVTLELGGSDPLIVLDDADVNLAVKIAVFGAFFHQGQICTSSKRIIVSEKVYE 297
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
FVK VE ++VG+P D + GP I + + ++ E K G ++ GG+
Sbjct: 298 AFVKKFVERVSQLKVGDPRDRTIEQGPLISKRQVESMIEFYEDSVKRGGKIMTGGK---W 354
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G Y PTV DV+ + I KEE+FGP++ +L+ EE I+ AN+T YGL+A + T N+
Sbjct: 355 DGNYFYPTVVTDVDRNFRIMKEEVFGPIRPVLRVKDDEEAIEVANDTEYGLSAAVVTRNV 414
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQA--PFGGFKDSGIGRENG 465
A +F + +E+G V +N+ +TM ++ PFGG K SGIGRE G
Sbjct: 415 TRAFKFVEQIESGMVHIND-VTMLEESHIPFGGIKASGIGREGG 457
>UniRef50_Q9STS1 Cluster: Betaine aldehyde dehydrogenase 2,
mitochondrial precursor; n=33; Magnoliophyta|Rep:
Betaine aldehyde dehydrogenase 2, mitochondrial
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 503
Score = 306 bits (752), Expect = 7e-82
Identities = 175/479 (36%), Positives = 251/479 (52%), Gaps = 11/479 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS--EWRL 66
+LFI +W + +T +P +I + F RN+ +W
Sbjct: 9 QLFIGGQWTEPVLRKTLPVVNPATEDIIGYIPAATSEDVELAVEAARKAFTRNNGKDWAR 68
Query: 67 ADASQRGKLLYKFA-DLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
A + R K L A +IER E LA LE+ D G + + Y LA+
Sbjct: 69 ATGAVRAKYLRAIAAKVIERKSE-LANLEAIDCGKPLDEAAWDMDDVAGCFEYYADLAEG 127
Query: 126 I---QGDTIPTDGDSFS-YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
+ Q + D+F Y LK+P+GV G+I PWN P+LM + KV +LAAGCT ++KP+
Sbjct: 128 LDAKQKTPLSLPMDTFKGYILKEPIGVVGMITPWNYPLLMAVWKVAPSLAAGCTAILKPS 187
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E LT +E G+P GV+NI+ G G +AG L HP V KI FTGS G I
Sbjct: 188 ELASLTCLELADICREVGLPPGVLNILTGLGTEAGAPLASHPHVDKIVFTGSTTTGSSIM 247
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
+A +K V+LELGGKSP+I+ +D D++ A+ + G F+ GQIC A SRL V I
Sbjct: 248 TSA-AKLVKPVSLELGGKSPIIVFDDVDIDKAVEWTMFGCFWTNGQICSATSRLLVHERI 306
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
D+F+ V++ K I++ +PF+E GP + + +VL + + EGA +L GG R
Sbjct: 307 ADEFLDKLVKWTKNIKISDPFEEGCRLGPVVSKGQYERVLKFVSNARNEGATVLCGGVRP 366
Query: 362 G--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
GY+++P + ++V M I +EE+FGP + F T +E I AN++ YGLA +
Sbjct: 367 EHLKKGYFVEPAIVSNVTTSMEIWREEVFGPALCVKTFSTEDEAIQLANDSQYGLAGAVL 426
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ +L + SK +AG VWVN QAP+GG K SG GRE G +E YL K V
Sbjct: 427 SNDLERCDRVSKAFQAGIVWVNCSQPCFCQAPWGGTKRSGFGRELGEWGLENYLSVKQV 485
>UniRef50_A0LTW2 Cluster: Betaine-aldehyde dehydrogenase; n=4;
Bacteria|Rep: Betaine-aldehyde dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 493
Score = 305 bits (750), Expect = 1e-81
Identities = 179/460 (38%), Positives = 255/460 (55%), Gaps = 12/460 (2%)
Query: 24 TFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLI 83
TF SP D V+A VA+G F +W ++R LL+ A+ I
Sbjct: 28 TFPDISPLDQQVLANVARGGPREVSAAVDAASAAFP---QWAATPRTERAALLHAVAEGI 84
Query: 84 ERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD---KIQGDTIPTDGDSFSY 140
E+ + LA +E+ DNG + ++ R S IP + AD ++ + T G ++
Sbjct: 85 EKRVDDLALVETLDNGGLLRSHRR--SVIPRAAYNFHFFADFLLQLGHEDFETRGHR-NH 141
Query: 141 TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGI 200
QP GV +I PWN P+++ +V ALAAG TVV+KP E PLT EAG+
Sbjct: 142 ISWQPAGVTAVITPWNAPLMLATWRVAPALAAGNTVVLKPPEWAPLTASLLADITAEAGL 201
Query: 201 PKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKS 260
P GV N+V G GE+AG AL P V +I+FTGS+ + I AA N + V+ ELGGK+
Sbjct: 202 PPGVFNVVQGIGEEAGAALVRDPRVRRIAFTGSVATARAIGHAAAENVIP-VSFELGGKN 260
Query: 261 PLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGN 320
P I+ DADL+LA+ +A + + GQ+C+A +RLYV +YD+F++ ++ A A RVG+
Sbjct: 261 PFIVFPDADLDLAVRHAVDQ-YDNAGQVCLAGTRLYVADAVYDEFLERFLQAAAAWRVGD 319
Query: 321 PFDESTVNGPQIDESMMNKVLGLIETGKKEGAN-LLAGGERIGTAGYYIQPTVFADVNDD 379
P E GPQI + ++ G + K GA LL GG G Y QPT+ +V DD
Sbjct: 320 PRSEDVDMGPQIHPDHLARIDGYVRRAKAAGATVLLGGGPHPELGGLYYQPTLLTNVADD 379
Query: 380 MTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVW 439
I +EE+FGPV + +F +EVI RAN+ YGLAA +FT + + A + + + AGTVW
Sbjct: 380 SEINREEVFGPVIVLHRFTDEDEVIRRANDNIYGLAAMVFTGDRSRAERVADRLVAGTVW 439
Query: 440 VNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
VN + +APFGG + SGIGRE G + + Y E K +
Sbjct: 440 VNCFYVRDLRAPFGGARLSGIGREGGTWSFDFYAEVKNTV 479
>UniRef50_P42269 Cluster: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenase; n=71; cellular
organisms|Rep: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenase - Escherichia coli
Length = 468
Score = 304 bits (747), Expect = 3e-81
Identities = 174/463 (37%), Positives = 253/463 (54%), Gaps = 19/463 (4%)
Query: 14 NEWVDAKD---GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
N W++ K+ + F T +P G V+A VA G F + W
Sbjct: 5 NHWINGKNVAGNDYFLTTNPATGEVLADVASGGEAEINQAVATAKEAFPK---WANLPMK 61
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+R +L+ + DLI+++ +A +E+ D G+ +++ ++ + + + ++ G
Sbjct: 62 ERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNGK 121
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
T P D +YTL QPVGVC L+ PWNVP + KV LA G T V+K +E +PLT
Sbjct: 122 TYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGITAVLKMSELSPLTAD 181
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAGIP GV+N+V G+G AG AL H DV +SFTG G+ I K AG L
Sbjct: 182 RLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAG---L 238
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K+ ++ELGGKSP++I DAD+ A+ A +F G+ C A SR+++Q IY +FVK A
Sbjct: 239 KKYSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKFA 298
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT------ 363
E A +RVG+P D +T G I + KV G I G +EGA LLAGG +
Sbjct: 299 -ERANRVRVGDPTDPNTQVGALISQQHWEKVSGYIRLGIEEGATLLAGGPDKPSDLPAHL 357
Query: 364 -AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G +++PTV ADV++ M +A+EEIFGPV +L F E + AN+ YGLA+ I+T +
Sbjct: 358 KGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEALRLANDVEYGLASYIWTQD 417
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENG 465
++ L+ ++ +EAG V+VN + FGG K GRE G
Sbjct: 418 VSKVLRLARGIEAGMVFVNTQFVRDLRHAFGGVKPR-TGREGG 459
>UniRef50_Q73RK8 Cluster: Betaine aldehyde dehydrogenase; n=1;
Treponema denticola|Rep: Betaine aldehyde dehydrogenase
- Treponema denticola
Length = 494
Score = 304 bits (746), Expect = 4e-81
Identities = 179/479 (37%), Positives = 249/479 (51%), Gaps = 14/479 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFID +++ +++G D +P + AK +G F +R
Sbjct: 13 QLFIDGKYIPSENGSIVDVINPVNNLPFAKAYRGTKTDCEKAIAAARKAFDEGP-YRKMS 71
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL--RILSGIPDSVRYLGSLADKI 126
A R KLL K A ++ER E LA +E+ + G Y C + I DS + A +
Sbjct: 72 AKDRSKLLLKAAQILERRAEELAVIETLECGKNYSACRYWEVPMAI-DSFEFFAGKARCL 130
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G +P++ + +Y P GV G ILPWN P LM KV LAAG TVV+KP L
Sbjct: 131 DGKVVPSEYGTLNYVTWNPCGVVGEILPWNGPFLMGCQKVNAILAAGNTVVIKPPSWGVL 190
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ +EAG P GVVN+V G G + G L V +S TG +E G+ I A
Sbjct: 191 SMILMASIYEEAGFPSGVVNVVTGSGAEVGNCLVESELVDMVSMTGGVETGREI-IAHSA 249
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+K + LELGGKSP I D D+ A +A G H GQICV+ +R+ VQ IY+ F+
Sbjct: 250 KLVKDIALELGGKSPNIFFEDVDIEQAARFAVYGFTNHAGQICVSGTRILVQRRIYEPFI 309
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----ERIG 362
K VE A ++ G+ FD ST I N V IE GKK+ A L+ GG E +
Sbjct: 310 KAMVETAYKLKPGDGFDPSTTINTLISREHANTVWEYIEKGKKQNARLVCGGNPYSEPLL 369
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G +I PT+FADV +M I + EIFGPV I FDT EE I AN T YGLA G+FT +
Sbjct: 370 KKGNFIPPTIFADVTPEMEIFQNEIFGPVACITPFDTEEEAISLANATKYGLAGGVFTKD 429
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAH-QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ A++ + + +G +++NNY + ++P G+K+SGI GI + Y+ KTV +
Sbjct: 430 IKRAIRVADRINSGQIYINNYFSKGMIESPGTGWKESGI----GIAGIHKYMISKTVFV 484
>UniRef50_A4X8T1 Cluster: Aldehyde dehydrogenase; n=1; Salinispora
tropica CNB-440|Rep: Aldehyde dehydrogenase -
Salinispora tropica CNB-440
Length = 488
Score = 304 bits (746), Expect = 4e-81
Identities = 172/424 (40%), Positives = 234/424 (55%), Gaps = 9/424 (2%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W + R LL + ADL+ERD LA L++ +NG + + + +RY A
Sbjct: 67 WAATRGNVRRDLLLRLADLVERDAADLAGLQTLENGCPRQFASAMPGVAIEHLRYYAGWA 126
Query: 124 DKIQGDTIPT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
DKI G +PT + YTL +P GV LI+PWN P++ + LAAG VV+KP+E
Sbjct: 127 DKIGGQVVPTWPVRAVDYTLDEPYGVVALIIPWNGPLVSVAQMLAPVLAAGNVVVLKPSE 186
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
P T EAG P GVVN+VPG G AL HPD+ K+ FTG + I
Sbjct: 187 LAPFTALRIGELALEAGFPPGVVNVVPGAAA-GGEALVRHPDIGKVHFTGGGNTARTIL- 244
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AA +L V LELGGKS ++ DAD+ +A A SGV GQ C +R+ V S +Y
Sbjct: 245 AAAAEHLVPVGLELGGKSAHVVFGDADIRMAARLAMSGVVALSGQGCANGTRVLVHSSVY 304
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIET--GKKEGANLLAGGER 360
D+ ++ + VG+P E T+ GP + E ++LG++E G + G LL+GGER
Sbjct: 305 DEMLRTVTARLARVPVGDPAQERTMMGPVVSEGACRRILGVVERARGARHG-RLLSGGER 363
Query: 361 IG---TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
+G AGY+I PTVFADV+ +A+EEIFGPV + FD+ EE + AN T YGL A
Sbjct: 364 LGGDLAAGYFIGPTVFADVDPASELAQEEIFGPVLAFTPFDSEEEALRLANGTRYGLGAY 423
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+ T++L A + S+ V AG+VWVN + APFGG + SG GR G V +L K
Sbjct: 424 LHTSDLRTAHRVSRAVAAGSVWVNGVPGVLPSAPFGGVRQSGWGRIGGEAGVREFLRPKN 483
Query: 478 VIIS 481
V I+
Sbjct: 484 VWIA 487
>UniRef50_Q5PMN7 Cluster: Possible aldehyde dehydrogenase; n=16;
Proteobacteria|Rep: Possible aldehyde dehydrogenase -
Salmonella paratyphi-a
Length = 494
Score = 303 bits (745), Expect = 5e-81
Identities = 169/470 (35%), Positives = 256/470 (54%), Gaps = 13/470 (2%)
Query: 19 AKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYK 78
A +G F +P G +IA V F WR QRG LL K
Sbjct: 28 AGNGTNFSVTNPATGKIIADVVSATPTQAEEAMQSARRAFD---VWRKMPTLQRGALLLK 84
Query: 79 FADLIERDFEYLAKLESYDNG--MVYKNCLRILSGIPDSVRYLGSLADKIQGDTI----P 132
AD + E LA+LES +G ++ L + + +RY A KI G+T+ P
Sbjct: 85 LADTLAAHREELAQLESVCSGKTILLSRGLELDQSVA-FLRYFAGWAGKITGETLNVSLP 143
Query: 133 TDGDS--FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ G+ ++T +QP+GV I+PWN I++ + K+ AL GCT+V+KP+E TPLT
Sbjct: 144 SMGEERYTAFTQRQPIGVVVGIVPWNFSIMIVIWKLAAALVCGCTIVIKPSEYTPLTLLR 203
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
KEAG P GV+N+V G G + L HPD AK+SFTGS+ G+ ++++A T++ K
Sbjct: 204 VAELAKEAGFPDGVINVVNGAGGEIAQQLIAHPDCAKVSFTGSVATGEKVRRSA-TSSGK 262
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
RVTLE GGK+ + +ND + + +QGQIC AA R Y+ D +
Sbjct: 263 RVTLEPGGKNAALFLNDLTEQAMVNGILEAGYLNQGQICAAAERFYLPQEKLDTVMTLLR 322
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ I G+P DE TV GP ++ + KVL LI+ ++EG ++ GGE + GY++QP
Sbjct: 323 QRLSEIVPGSPLDEKTVMGPLANQVQLEKVLRLIQRAREEGDTIVYGGETLPGEGYFLQP 382
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
T + + T+ EE FGPV S + + +E + N++ +GLAA +++ N++ AL ++
Sbjct: 383 TAVKVRSKNSTLIHEETFGPVCSFIGYQNEKEALSHINDSPFGLAASVWSENMSKALHYA 442
Query: 431 KHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ ++AG VWVN + + PFGG K SGIGRE G ++ Y E K+V++
Sbjct: 443 EDIDAGMVWVNMHTFLDPAVPFGGMKGSGIGREFGSAFIDDYTELKSVMV 492
>UniRef50_A0B664 Cluster: Betaine-aldehyde dehydrogenase; n=1;
Methanosaeta thermophila PT|Rep: Betaine-aldehyde
dehydrogenase - Methanosaeta thermophila (strain DSM
6194 / PT) (Methanothrixthermophila (strain DSM 6194 /
PT))
Length = 475
Score = 303 bits (745), Expect = 5e-81
Identities = 171/475 (36%), Positives = 253/475 (53%), Gaps = 7/475 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+ I+ E V+ G +P + +A+VA G F W A
Sbjct: 6 MLINGERVEGASGRYDLIHNPANQEAVAEVAIGDVIDAVKALESAQRAFPG---WSSIPA 62
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
++R LL+ A+++ + +AKL + + G ++ R + DS+ Y + G+
Sbjct: 63 TKRCTLLHDAAEIVRERADNIAKLLTMEMGKPIRDSRREVLSAADSLDYFAEEGLRNIGE 122
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
I GD+ S ++QPVGV LI PWN P+ + KV ALAAGCT V KP+ P+
Sbjct: 123 WISA-GDTRSIVVRQPVGVVSLITPWNYPVELLAWKVGPALAAGCTAVAKPSSLAPVAAT 181
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+AG+P GV+NIV G G+ G L +P KISFTG G+ I A L
Sbjct: 182 EFVMAINDAGLPPGVMNIVHGSGDTIGAELVKNPIPRKISFTGETSTGRWIMGTAA-EYL 240
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KR++LELGG +P+I+ +DAD++ A F + GQ+C++ +R+YV I + F +
Sbjct: 241 KRISLELGGHAPMIVFDDADIDTAAGACVRRAFGNMGQVCISVNRVYVDESIAEDFTEKV 300
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-ERIG-TAGYY 367
+ +R+G+P D GP + E+ K IE GAN+L GG E G T GYY
Sbjct: 301 IRRTLELRIGDPLDPDVDLGPMVSEAQRRKTREHIEDAVDRGANILCGGREPEGFTRGYY 360
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
PTV DV+ M I +EE FGPV I++F EE + AN+T YGLAA ++T +L+ A+
Sbjct: 361 FMPTVLTDVDHTMRIMREETFGPVAPIMRFRDEEEAVRLANDTEYGLAAYVYTNSLSRAV 420
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+ ++ +EAG+V VN + APFGG+K SGIGRE + +E Y+E K + + L
Sbjct: 421 RTAERLEAGSVGVNVGSVIDRHAPFGGWKQSGIGRELSHRGIEEYMEIKHIRLGL 475
>UniRef50_A0IVF9 Cluster: Aldehyde dehydrogenase; n=1; Serratia
proteamaculans 568|Rep: Aldehyde dehydrogenase -
Serratia proteamaculans 568
Length = 506
Score = 303 bits (744), Expect = 6e-81
Identities = 166/424 (39%), Positives = 244/424 (57%), Gaps = 13/424 (3%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W+ R +L+ K ADL+E D E +A++++ D G R +VR+ A
Sbjct: 77 WKAQGQQARAQLVLKLADLLENDSERMAQMDALDVGRCISEVRR---DYHTAVRHYRYFA 133
Query: 124 DKIQG--DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
I G DT + D +S ++P+GVCG I+PWN P +M K+ AL G T+V+K
Sbjct: 134 SVIMGHEDTGRSIADGYSLAKREPLGVCGQIIPWNAPAIMAAFKLAPALVTGNTLVLKVD 193
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
E L+ P GVVNI+ G G G ALT + V K+SFTGS VG+++
Sbjct: 194 ENASLSTLELGKHISNV-FPAGVVNIITGLGNVVGSALTGNKKVRKLSFTGSTAVGRMVA 252
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMND-ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
KAA L VTLELGGKSP I+ D +D++ + + GQ C+A +RL+V +
Sbjct: 253 KAAA-ERLVPVTLELGGKSPNIVFPDISDIDAVVDNVSFAALHNNGQSCLAGTRLFVHAD 311
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
IY+ F VE K +R+G+P DE + + E +VL I+TG EGA LL GG R
Sbjct: 312 IYESFSAKLVESFKRVRIGSPLDEHSTVSCLVSEKQGKRVLSYIQTGIDEGAALLVGGNR 371
Query: 361 IGTAG----YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
+G Y+I+PT+FA N M I +EEIFGPV +++K+ +E+I +AN+T YGLA+
Sbjct: 372 RAISGCDNGYFIEPTIFAAENH-MQICQEEIFGPVLTLIKWSDYDEMIKQANDTEYGLAS 430
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
GI+T++L NA++ + +EAG+VW+N Y + FGG+K+SG+GRE + + AY + K
Sbjct: 431 GIYTSSLKNAMETADKLEAGSVWINRYSNITEGTAFGGYKNSGMGREFCKETLNAYTQIK 490
Query: 477 TVII 480
T+ +
Sbjct: 491 TITL 494
>UniRef50_A6VRB2 Cluster: Succinic semialdehyde dehydrogenase; n=2;
Gammaproteobacteria|Rep: Succinic semialdehyde
dehydrogenase - Marinomonas sp. MWYL1
Length = 488
Score = 303 bits (743), Expect = 8e-81
Identities = 170/477 (35%), Positives = 253/477 (53%), Gaps = 7/477 (1%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P + ++ +I EWV+AK G+TF +P +G I VA +
Sbjct: 8 PSLLKSRSYIGGEWVEAKSGKTFAITNPANGEHIIDVAD---LGAEETTLAVEAAEKAQK 64
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
EW+ A +R LL ++ LI + + LA L + + G + ++ + +
Sbjct: 65 EWQGRTAKERATLLRRWNQLILDNQDDLATLMTLEQGKPFAEAKGEVAYGASFIDWFADE 124
Query: 123 ADKIQGDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
A ++ GD IPT D T+KQP+GV I PWN PI M K ALAAGC +V+KP+
Sbjct: 125 ARRLNGDVIPTFAKDKRVLTIKQPIGVVAAITPWNFPIAMITRKAGPALAAGCAIVIKPS 184
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDA-GVALTHHPDVAKISFTGSLEVGKLI 240
++TPL +AGIP GV+N+V G A G LT HP V K+SFTGS VGKL+
Sbjct: 185 DETPLCALALAELAHQAGIPAGVLNVVVGKDAKAIGGVLTGHPTVRKLSFTGSTPVGKLL 244
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
+KR ++ELGG +P I+ +DADL+ A+ A + + + GQ CV A+R+ VQ
Sbjct: 245 LSQCA-QTVKRTSMELGGNAPFIVFDDADLDAAVEGAIASKYRNAGQTCVCANRILVQEV 303
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
+YD F + + + G+ F E GP I+ + ++KV L+ +GA L GG +
Sbjct: 304 VYDIFAEKLAKRVATFKTGDGFAEGVNIGPLINPAAISKVELLVGDAITKGAKALIGGSK 363
Query: 361 IGTAG-YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AG + +PT+ V +DM I EIFGPV + KF T +E + ANNT +GLA+ +
Sbjct: 364 ATAAGAQFFEPTILTGVTEDMDIFSNEIFGPVAPLFKFKTEDEAVAMANNTPFGLASYFY 423
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ N+ + S+ +E G V +N + + APFGG K+SG GRE ++ Y+E K
Sbjct: 424 SQNIARIWRVSEALEYGMVGINEGIISSEVAPFGGVKESGSGREGSQYGIDEYVEIK 480
>UniRef50_A4F0G0 Cluster: Aldehyde dehydrogenase family protein;
n=4; Rhodobacteraceae|Rep: Aldehyde dehydrogenase family
protein - Roseobacter sp. SK209-2-6
Length = 485
Score = 303 bits (743), Expect = 8e-81
Identities = 178/472 (37%), Positives = 250/472 (52%), Gaps = 10/472 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI +W G+ +P DG I ++A+GQ W A
Sbjct: 15 FISGQWQPPVGGKNLPLVNPSDGQEICRIARGQQADIDLAVGAAKEALAGG--WGRMTAL 72
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+RG++L L+ E LA LE+ D G + + G ADK+ G+T
Sbjct: 73 ERGRILTSIGQLVLERVEDLAALEAMDVGKPLTQARADAVALARYCEFYGGAADKVMGET 132
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
IP YTL++P GV G I+PWN P+ + + ALA G V+KPAE+ LT
Sbjct: 133 IPYLDGYTVYTLREPHGVTGHIVPWNYPMQIIGRSIGAALAMGNACVLKPAEEACLTALA 192
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+EAG+P G +NIVPG G +AG AL+ H V ISFTGS+ G L+Q+AAG N+
Sbjct: 193 FGQIAQEAGLPAGALNIVPGLGGEAGAALSAHSGVDHISFTGSVRTGALVQQAAGA-NVV 251
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGKSP ++ +DADL+ A+P+ + + GQ C A+SR+ VQ G+Y++ VK +
Sbjct: 252 PVTLELGGKSPQLVFDDADLDAALPFLVNAGIQNAGQTCSASSRILVQRGLYEE-VKARM 310
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---GYY 367
A A P E GP I V G I GK + A G + +A G Y
Sbjct: 311 SAAYAELTVGPATEDQRLGPLISSRQKEIVEGYIAQGK--DLEVAAKGRIVDSADPKGAY 368
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
I P +FADV +A+EEIFGPVQ ++ F+T EE ++ AN+T YGL A ++T + +
Sbjct: 369 IAPMLFADVPPTHALAQEEIFGPVQVLIPFETEEEALEIANSTEYGLVASVWTRDGARQM 428
Query: 428 QFSKHVEAGTVWVNNY-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ +K + AG V++NNY + PFGG SG GRE G +A+ + + KTV
Sbjct: 429 RLAKKLRAGQVFLNNYGAGGGVELPFGGVGKSGHGREKGFEALYGFSQLKTV 480
>UniRef50_A6F548 Cluster: Aldehyde dehydrogenase; n=1; Marinobacter
algicola DG893|Rep: Aldehyde dehydrogenase -
Marinobacter algicola DG893
Length = 497
Score = 302 bits (742), Expect = 1e-80
Identities = 166/477 (34%), Positives = 263/477 (55%), Gaps = 14/477 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
++ I+ ++V + G+T+ T +P +A V F W+
Sbjct: 24 QMTINGKFVKGQSGKTYTTINPSTDQPLADVPFATAEDVKSAVASAKAAFPG---WKKLH 80
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+RGK+L + + E L++ D G Y+ + + + + +L +++G
Sbjct: 81 VDERGKMLKALSRAVRERAEMFGMLDALDCGNPYQAMVDDANKGAGLLEHFSNLGMELKG 140
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T+PT G +YT +P GV ILP+N PI + K+ +AL AG TVV+K A+QTPL+
Sbjct: 141 QTVPTPGGGLNYTRLEPFGVVARILPFNHPISFAVGKIASALIAGNTVVMKIADQTPLSA 200
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+E +P GVVN++ G G G +L HPD+ +I+FTGS+ G LI + AG
Sbjct: 201 LLFGKLIQEH-LPPGVVNVITGDGATTGASLVSHPDIHRIAFTGSVATGNLISQQAG--- 256
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFF--HQGQICVAASRLYVQSGIYDKFV 306
+ ++LELGGK+PLII D D+ A +G+ F QGQ C + SR++V ++D+FV
Sbjct: 257 IAVLSLELGGKNPLIIYPDVDVQKVADAAVAGMNFTRSQGQSCGSNSRVFVHRDLHDEFV 316
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG---- 362
V+ + I+VG+ + T GP + ++V+ I++ K EGA L+ GG
Sbjct: 317 SEVVKRVEKIKVGHADADDTEMGPVVTRQHYDRVMHYIDSAKSEGAKLMTGGGHAKGEDL 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY+I+PTVF +V DMTIA+EEIFGPV SIL +D ++++ N YGL A ++T +
Sbjct: 377 ADGYFIEPTVFDEVTHDMTIAREEIFGPVMSILVWDDEASMMEQVNGVEYGLCANVWTND 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQ-APFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++ AL+ +EAG VW+N + + APFGG K+SGIGRE+ + ++ +EK +
Sbjct: 437 ISTALRVGDDIEAGYVWINGHGGKRFKGAPFGGVKNSGIGREHDTSEIRSFTQEKNI 493
>UniRef50_Q9AH30 Cluster: 2-aminomuconic semialdehyde dehydrogenase;
n=8; Proteobacteria|Rep: 2-aminomuconic semialdehyde
dehydrogenase - Pseudomonas putida
Length = 491
Score = 301 bits (740), Expect = 2e-80
Identities = 177/495 (35%), Positives = 264/495 (53%), Gaps = 20/495 (4%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
+K+ + +++ +W ++ TFD SP DGS++A V + + EW
Sbjct: 1 MKHYRNYVNGKWTESS--RTFDDVSPVDGSLVAIVHEASRELVDEAVKSGHQAL--SGEW 56
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
A+QR LL + AD +ER E D G + I +P + + AD
Sbjct: 57 GRTTATQRVALLRRIADEMERRQGDFLAAEMADTGKPHSMASSI--DVPRGIANFRTFAD 114
Query: 125 KIQGDTIPT------DGD-SFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
+ + + DG + +Y+ ++P+GV G+I PWN+P+L+ KV ALA G TVV
Sbjct: 115 ILATAPVDSHRLDLADGAYALNYSARKPLGVVGVISPWNLPLLLMTWKVAPALACGNTVV 174
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGED-AGVALTHHPDVAKISFTGSLEV 236
VKP+E TP T + AG+P GV N+V GFG + AG ++ HPD++ I+FTG
Sbjct: 175 VKPSEDTPGTATLLAEVMEAAGVPPGVFNLVHGFGPNSAGEFISSHPDISAITFTGESRT 234
Query: 237 GKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
G I +AA +K V+ ELGGK+ II D D + + +F + GQ+C+ + R+Y
Sbjct: 235 GTTIMRAAA-EGVKPVSFELGGKNAAIIFADCDFDKMLDTMMRALFLNSGQVCLCSERVY 293
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
V+ +YD+F VE K +++ P D +T GP I +KVLG E + EGA LA
Sbjct: 294 VERPLYDRFCAALVERIKGMKIDWPQDPATQMGPLISAKHRDKVLGYFELARTEGATFLA 353
Query: 357 GG--ERIGTA---GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTN 411
GG G + G ++QPTV + DD +EEIFGP+ + FD +EVI RAN+T
Sbjct: 354 GGGVPHFGDSRDDGAWVQPTVITGLGDDARSVREEIFGPICHVSVFDNEQEVIARANDTR 413
Query: 412 YGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEA 471
YGLAA I+T+NL A + S+ + G WVN + + PFGG SGIGRE G+ ++
Sbjct: 414 YGLAATIWTSNLGRAHRVSEAMRVGISWVNTWFLRDLRTPFGGAGLSGIGREGGMHSLNF 473
Query: 472 YLEEKTVIISLPKKL 486
Y E V I + +++
Sbjct: 474 YSELTNVCIRIDEEV 488
>UniRef50_Q20352 Cluster: Aldehyde dehydrogenase protein 11, isoform
a; n=5; Eumetazoa|Rep: Aldehyde dehydrogenase protein
11, isoform a - Caenorhabditis elegans
Length = 687
Score = 301 bits (740), Expect = 2e-80
Identities = 158/423 (37%), Positives = 231/423 (54%), Gaps = 5/423 (1%)
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
+W + +R ++L K DL++ +A E NG + D+ + +
Sbjct: 258 QWAKSSWMERSEILKKTGDLLKTHCNDIAYWECISNGKPIAEAKADVLSCVDTFYFYSGI 317
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
A + G +P D ++YT + PVGV I WN PI K ALA G V+ KP+
Sbjct: 318 ASDLLGQHVPLDASRYAYTRRLPVGVVAAIGAWNYPIQTCSWKTAPALACGNAVIYKPSP 377
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
+P+T K AG+P GV N++ G E A L HH V+K+SFTGS+ GK I K
Sbjct: 378 LSPVTALILAEILKSAGLPDGVFNVIQGDAETAQ-DLIHHDGVSKVSFTGSIPTGKKIMK 436
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A N+K VTLELGGKS LI+ +DAD++ A+ A F+ QGQ+C AS++ V +
Sbjct: 437 ACADRNIKPVTLELGGKSALIVFDDADIDSAVSCAMMANFYSQGQVCSNASKVLVHKSVL 496
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+F K V++ + +++G+P E T G I NKV G I T EGA L GG+R+
Sbjct: 497 KEFTKKLVDHTQKMKIGDPLKEDTQVGSHISAEHRNKVEGYISTAIAEGATKLCGGDRVA 556
Query: 363 T----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
G+Y+ P + + MT+ +EEIFG V I+ FDT +E I AN+T+ GLAAG+
Sbjct: 557 VHGLENGFYLSPCILTGITPKMTVYREEIFGSVLLIIPFDTEDEAIKIANDTDMGLAAGL 616
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
T +L+ + + S+ + AG V+VN Y ++ PFGG +SG GRENG +E Y K+V
Sbjct: 617 VTKDLSRSYRVSEQLNAGNVYVNTYNDVSPLVPFGGVGESGFGRENGTAVLEHYTHLKSV 676
Query: 479 IIS 481
++
Sbjct: 677 FVN 679
>UniRef50_Q4FMK5 Cluster: Succinate-semialdehyde dehydrogenase
(NAD(P)); n=2; Candidatus Pelagibacter ubique|Rep:
Succinate-semialdehyde dehydrogenase (NAD(P)) -
Pelagibacter ubique
Length = 480
Score = 301 bits (739), Expect = 3e-80
Identities = 168/469 (35%), Positives = 248/469 (52%), Gaps = 7/469 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID W + + ET+ +P V+ +K + WR
Sbjct: 8 FIDGNWSPSSNKETYKVINPATEEVLGHASKATPVDVDRALKSAEKGL---AIWRKTPPW 64
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
QR L K AD++ + LAK + +NG + +G D + +I G
Sbjct: 65 QRAYTLRKIADMVREKKDVLAKWMTLENGKPLAEGVGETNGAADIFEWNAEETKRIYGQI 124
Query: 131 IPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+ + D+ + QP+GV + PWN P+++ K+ TALAAGC+V++KP TP
Sbjct: 125 VESRFEDTRVHVYYQPIGVVAALSPWNFPLVLAARKISTALAAGCSVIIKPDTITPGVVM 184
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+E GIP GVVN++ G L + KIS TGS VGK+I K A + L
Sbjct: 185 ELVDICRECGIPAGVVNLLSGDPPAIASQLISSDIIKKISVTGSTRVGKIILKQAA-DKL 243
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
+RVT+EL G SP I+ +DADLN A A + F + GQ+C++ +R Y+Q D+FV
Sbjct: 244 QRVTMELSGHSPFIVFDDADLNKATDIAIAAKFRNNGQVCISPNRFYIQESKKDEFVGLF 303
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--TAGYY 367
+E K +++GN D T GP + +N+V L+E K+EGA +L GG+R G+Y
Sbjct: 304 IEKTKKLKIGNGMDPDTQLGPLTTQKRLNEVEELVEKTKQEGAKVLLGGKRPAGFNKGFY 363
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+PTVF DV DD TI K+E FGP+ +L F + +EVI+RAN+ + GL + I T +++ A
Sbjct: 364 YEPTVFDDVKDDFTIMKQEPFGPLVPMLSFKSFDEVIERANDNDLGLCSYICTNSMDKAY 423
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ S+ +EAG VN + +APFGG K +G GRE G A++ YL K
Sbjct: 424 RASELMEAGIACVNTGVVAVAEAPFGGIKQTGYGREGGSNAIKDYLNVK 472
>UniRef50_Q2FM54 Cluster: Aldehyde dehydrogenase; n=1;
Methanospirillum hungatei JF-1|Rep: Aldehyde
dehydrogenase - Methanospirillum hungatei (strain JF-1 /
DSM 864)
Length = 471
Score = 301 bits (739), Expect = 3e-80
Identities = 161/463 (34%), Positives = 251/463 (54%), Gaps = 9/463 (1%)
Query: 23 ETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADL 82
E+++ ++P DGS++ V G F+ W D R KLL+ A L
Sbjct: 11 ESYEVYNPADGSLVGSVPAGTPDDVNNAVSTAWEAFR---SWSQTDPLDRSKLLFSAAQL 67
Query: 83 IERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTL 142
+ D + LA+L + + G + + ++G + Y S++ ++GD + +
Sbjct: 68 VRADQKDLARLLTREQGKPLRESMNEVAGFARVLEYYASISGTLKGDYGLSKTYGHMMVV 127
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
+QP+GVC I+PWN+P+L+ K+ LA G T++VKP+ PLT G+P+
Sbjct: 128 RQPLGVCAAIIPWNMPVLIMGWKIGPVLATGNTMIVKPSTTAPLTCKALAGCLYRVGVPE 187
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
V+ +V G GE G AL HPD+ +SFTG++ G + + A LK+ LELGG +
Sbjct: 188 SVLQLVTGSGEVVGEALARHPDIKSLSFTGAVPTGIQVAEHAA-KTLKKTILELGGSDAM 246
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
I+ DADL A A SG FF+ GQ C A R++V + IY FV+ E A A++VGN
Sbjct: 247 IVCKDADLEAAAKGAVSGRFFNCGQTCTAIKRVFVDTSIYAPFVRRVRELADALQVGNGL 306
Query: 323 DESTVNGPQIDESMMNKVLGLI-ETGKKEGANLLAGGERIGTAGY----YIQPTVFADVN 377
GP + + V L+ ET +L+GG+ + Y + PT+ DV+
Sbjct: 307 LAGVDMGPVHSKRQRDTVHSLVQETVDNRLGTVLSGGKIPDSDPYAMGSFYLPTILTDVD 366
Query: 378 DDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGT 437
D + +EE+FGPV I +FD++ + I+RAN T +GL A ++T ++ + ++ ++AG
Sbjct: 367 PDAPVMREEVFGPVLPISEFDSISDAIERANATRFGLGASVWTHDMRTISRATQELDAGI 426
Query: 438 VWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
VWVN +L + + PFGG K SG+GRENG A+ YLEEKT++I
Sbjct: 427 VWVNQHLRIPPEVPFGGVKSSGLGRENGRYALFHYLEEKTILI 469
>UniRef50_A5UWF0 Cluster: Aldehyde dehydrogenase; n=5; Bacteria|Rep:
Aldehyde dehydrogenase - Roseiflexus sp. RS-1
Length = 484
Score = 301 bits (738), Expect = 3e-80
Identities = 172/478 (35%), Positives = 251/478 (52%), Gaps = 13/478 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+ID +V+ F+ F P VI +G+ F + W A A+
Sbjct: 11 YIDGAFVEGT--RRFEIFYPATNQVIGSAPEGREEEVDAAVQAATRAF---ASWGRASAA 65
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+R ++L FAD I L +E++D G + +N + + ++ + +A +
Sbjct: 66 ERRRVLRAFADAIRAHTAELELIETWDVGRPIRENRAGYVQRLAANIEFFADVAVTHGSE 125
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
P D +Y L+ PVGV LI PWNVP+L K+ ALA G TVV+KPAE TP+
Sbjct: 126 AYPMDSGYINYVLRHPVGVAALITPWNVPMLQATWKIGPALAFGNTVVLKPAEFTPIGAW 185
Query: 190 XXXXXXKEAGIPKGVVNIVPGFG-EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
AG+P GV+N+V GFG E AG LT HP V ISFTG GK I A
Sbjct: 186 KLAQIAHSAGLPPGVLNVVHGFGPESAGALLTQHPGVHLISFTGESGTGKTIMGVAA-RT 244
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LKR++ ELGGK II DADL+ A+ + FF+QG+ C+A RL V+ IYD+F++
Sbjct: 245 LKRLSFELGGKGANIIFADADLDRAVAISLRSSFFNQGEFCLAGPRLLVERPIYDRFLQR 304
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-----T 363
+ + +RVG+P D T G I + +V I+ + A ++ GG+R
Sbjct: 305 FIAATQQLRVGDPMDPETTVGALIAPEHLQRVSSYIDIARGTQAEIVLGGDRPNLPAPFN 364
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G ++ PT+ V + +EEIFGPV ++ FD +E I AN YGL+A + T ++
Sbjct: 365 RGNFLNPTIIVGVQPQDRVCQEEIFGPVVTVAPFDGEDEAIAIANGVAYGLSAVVQTRDV 424
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
A++ + ++AGTVWVN++ + PFGG K SGIGRE G ++E + E KTV +S
Sbjct: 425 GRAVRVAGAIDAGTVWVNDFFVRDLRVPFGGMKQSGIGREGGHYSLEFFTEAKTVCLS 482
>UniRef50_A4FGR5 Cluster: Betaine-aldehyde dehydrogenase; n=4;
Actinobacteria (class)|Rep: Betaine-aldehyde
dehydrogenase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 497
Score = 301 bits (738), Expect = 3e-80
Identities = 168/459 (36%), Positives = 248/459 (54%), Gaps = 9/459 (1%)
Query: 26 DTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIER 85
D P G+V+A++A+ FQR WR AS+RG LL A+ I
Sbjct: 35 DDVDPSRGAVVARLARCGAAEVAGAVATARETFQRR--WRRRPASERGSLLRAVAERIRA 92
Query: 86 DFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQP 145
+ E LA ES + G + ++ + GS+ + + G+ +P GD+ + ++P
Sbjct: 93 EAEELAVQESTETGKPLRQGRADVAAAARYFEFYGSVVEALHGEVVPQVGDNQVFVHREP 152
Query: 146 VGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVV 205
GV G I+ WN P+ + +LAAG V+KPAE+ L EAG+P G
Sbjct: 153 HGVTGHIVAWNYPLQITARSAAASLAAGNCCVIKPAEEASLGAVRLAEIALEAGVPAGCF 212
Query: 206 NIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIM 265
N+V G GE+AG AL P V ++FTGS+EVG+L+ AG NL T+ELGGKSP I+
Sbjct: 213 NVVTGLGEEAGAALAAAP-VDHLAFTGSVEVGRLVAATAG-RNLVPTTMELGGKSPNIVF 270
Query: 266 NDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDES 325
+DADL LA+P + + + GQ C A SRL V I+ + V G E +A+R+G ++
Sbjct: 271 DDADLELALPTIVNSIVQNGGQTCSAGSRLLVHRDIHRRVVDGIAERFRALRLGPALEDP 330
Query: 326 TVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---GYYIQPTVFADVNDDMTI 382
+ GP I + +V GL+ G +G + G G GY+ +PT+ DV D +
Sbjct: 331 DL-GPLISAAQRERVAGLVGDGAGDGRLVTGGRVAEGPGLDDGYFFEPTLVDDVAPDSLL 389
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
A+EE+FGPV ++ FD L+E + AN T++GL A ++T N+ A S+ ++AG V+VN
Sbjct: 390 AREEVFGPVLAVTPFDDLDEAVRIANGTDFGLVAAVWTRNVGRAHWISRELDAGQVFVNT 449
Query: 443 Y-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
Y + PFGG K+SG GRE G + + AY KTV +
Sbjct: 450 YGAGGGVELPFGGVKNSGFGREKGFEGLLAYTRTKTVAV 488
>UniRef50_Q5B1Z5 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 483
Score = 301 bits (738), Expect = 3e-80
Identities = 166/405 (40%), Positives = 233/405 (57%), Gaps = 7/405 (1%)
Query: 81 DLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDGDSFS 139
+L+ERD E LA LES G + ++ + + RY DKI G++ P +
Sbjct: 37 NLVERDAERLAILESLPTGKPVTPTIHFDIAHMLEVWRYYAGWTDKISGESYPESNGVYK 96
Query: 140 YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAG 199
+P+GVC I WN + K+ A+AAG + KP+E++P EAG
Sbjct: 97 IVRHEPLGVCAGIASWNATFMYIGWKIAPAVAAGNCFIFKPSEKSPFGTLALGALFAEAG 156
Query: 200 IPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGK 259
P GVV I+ G G + G AL H D+AKISFTGSL GK +Q+AA +NLK+VTLELGGK
Sbjct: 157 FPAGVVQILNG-GAETGAALARHMDIAKISFTGSLGGGKAVQEAATKSNLKKVTLELGGK 215
Query: 260 SPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG---AVEYAKAI 316
SP ++ DA+L A+ G F+ GQ+CVA SR+ VQ I++KF +G A E +
Sbjct: 216 SPAVVFADAELERALGGV-CGFLFNSGQVCVATSRVLVQKPIFEKFTQGLKSAFEQTSST 274
Query: 317 RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADV 376
+P D++ GP +D++ +K++ I GK+ A LL GGER G G++I+PT+F +
Sbjct: 275 LGADPLDKNVSYGPIVDKAQFDKIMSYIAIGKQT-ATLLTGGERKGDKGFFIKPTIFVNP 333
Query: 377 NDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAG 436
+ I KEEIFGPV + F+T EE I AN T YGLAA ++T+N++ AL+ S +E G
Sbjct: 334 EPESPIVKEEIFGPVMVVQTFETEEEAIALANATVYGLAASVYTSNIDRALRVSSALECG 393
Query: 437 TVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
V VN+ FGG K SG GRE G+ + Y E K+V I+
Sbjct: 394 GVAVNSPFLPQVNTAFGGIKASGKGRELGLYGLLEYTEAKSVHIT 438
>UniRef50_Q12HD9 Cluster: Aldehyde dehydrogenase; n=34;
Proteobacteria|Rep: Aldehyde dehydrogenase - Polaromonas
sp. (strain JS666 / ATCC BAA-500)
Length = 505
Score = 300 bits (736), Expect = 6e-80
Identities = 164/474 (34%), Positives = 241/474 (50%), Gaps = 5/474 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T+LFI EW +A DG + F+P G I +VA F+ WR
Sbjct: 33 TQLFIAGEWQEAADGRSLAVFNPATGKEIGRVAHAAKVDLDRALAAAQQGFET---WRKV 89
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R K++ + A L+ +A + + + G D + + ++
Sbjct: 90 PAFERSKIMRRAAGLMRERAGEIAAVLTQEQGKPLAEAKVEAMAAADIIEWFAEEGFRVY 149
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G +P+ + LK PVG PWN PI + K+ ALA GC+++VK E+TP
Sbjct: 150 GRVVPSRNLATRQLVLKDPVGPVAAFTPWNFPINQAVRKLSAALATGCSIIVKAPEETPA 209
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+AGIP GV+ +V G + L HP + KI+FTGS VGK + AG
Sbjct: 210 GPAALIQAFADAGIPAGVIGLVYGNPAEISGYLIPHPVIRKITFTGSTPVGKQLAALAG- 268
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
++KRVT+ELGG +P+I+ DAD+ LA+ AG F + GQ+C++ +R V I + F
Sbjct: 269 QHMKRVTMELGGHAPVIVAEDADVELAVKAAGGAKFRNAGQVCISPTRFLVHESIRNDFA 328
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
V++A+ ++VG+ E GP + + + + + GA + AGGERIG G
Sbjct: 329 AALVKHAQGLKVGDGLGEGIQMGPLANPRRLTAMAEFTQDAVQRGAKVAAGGERIGDLGN 388
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ PTV DV D + +E FGP+ +I F+TL+E I AN +GLA FT +L NA
Sbjct: 389 FWAPTVLTDVPLDAKVFNDEPFGPMAAIRSFNTLDEAIAEANRLPFGLAGYAFTRSLKNA 448
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
S+HVE G +W+N + PFGG KDSG G E G +A+EAYL + V I
Sbjct: 449 HALSQHVEVGMLWINQPAAPWPEMPFGGVKDSGYGSEGGPEALEAYLNTRAVSI 502
>UniRef50_Q8CV96 Cluster: Aldehyde dehydrogenase; n=7; cellular
organisms|Rep: Aldehyde dehydrogenase - Oceanobacillus
iheyensis
Length = 497
Score = 299 bits (735), Expect = 8e-80
Identities = 174/489 (35%), Positives = 263/489 (53%), Gaps = 13/489 (2%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E K FID +WVD + T +P +G I +V + E
Sbjct: 7 ETDVLKNFIDGKWVDVNN--TTAVTNPANGERIVQVPLSDQSHVEEAVQAA---IKAQKE 61
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL-RILSGIPDSVRYLGSL 122
W L A QR ++LY+ +++ E L++L + +NG V + + GI D Y+
Sbjct: 62 WALVPAPQRAEVLYRVGMIMKDKKERLSRLLTMENGKVLEEARGEVQEGI-DMAFYMAGE 120
Query: 123 ADKIQGDTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
++ G T P + D F+ + + PVGV G+I PWN PI + K A+ AG VV KPA
Sbjct: 121 GRRLFGQTTPAELKDKFAMSQRVPVGVVGIITPWNFPIAIATWKSFPAIVAGNAVVWKPA 180
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
+TP+ +EAG+P GV+N+V G G + G ++ H D+ ISFTGS + G+ I
Sbjct: 181 TETPIMAYELAKIFEEAGLPSGVINVVFGKGSEVGDSMVQHKDIRVISFTGSNDTGRNIA 240
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
G LK+V+LE+GGK+ +I+M+DADL+LA+ F GQ C A SR+ V +
Sbjct: 241 SDCG-KQLKKVSLEMGGKNAVIVMDDADLDLAVEGILWSAFGTSGQRCTACSRVIVHHKV 299
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
+ + + +GN ++ GP I+E+ +NK+ IE GK+EGA LLAGG
Sbjct: 300 KKTLEERLLAAMDHLTIGNGLEDGIKVGPIINEAGLNKIKKYIEVGKQEGATLLAGGTEW 359
Query: 362 GT--AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
T GYY PT+F D DM IA+EEIFGPV S+++ + EE I+ N +GL++ IF
Sbjct: 360 ETNNPGYYFTPTLFTDAKPDMRIAQEEIFGPVVSLIEVSSFEEAIEVNNQVTFGLSSSIF 419
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAH-QAPFGGFKDSGIG-RENGIKAVEAYLEEKT 477
T ++N + + ++ G V+VN T A PFGG K +G G R++G++A++ + E K
Sbjct: 420 TKDVNRVFKAQRDLDTGIVYVNAGTTGAEIHLPFGGTKGTGNGHRDSGVQALDVFTEWKA 479
Query: 478 VIISLPKKL 486
+ + KL
Sbjct: 480 IYVDYSGKL 488
>UniRef50_Q26FT5 Cluster: Aldehyde dehydrogenase; n=9; Bacteria|Rep:
Aldehyde dehydrogenase - Flavobacteria bacterium BBFL7
Length = 492
Score = 299 bits (734), Expect = 1e-79
Identities = 164/480 (34%), Positives = 253/480 (52%), Gaps = 12/480 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K FI+N G D + P G V ++ F+ +W
Sbjct: 15 KNFINNNEHIPLSGLWLDNYEPASGLVYGQIPNSNEDDVEKAYQAANAAFK---DWSTTS 71
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQ 127
+R +++ + ADLIE + E LA ES DNG + + + R+ G+ +
Sbjct: 72 IDERSRIMLRIADLIEENLEELAAAESRDNGKPLWLATAVDIPRASSNFRFYGNAITQYS 131
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
D T G ++ ++T+++P+GV G I PWN+P+ +F K+ A+AAG VV KP+E TP
Sbjct: 132 SDAHETTGKNTMNFTMRKPIGVVGCISPWNLPLYLFSWKIAPAIAAGNCVVAKPSEVTPA 191
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T K+AG+P GV+NIV G G G A+ HP + ISFTG G+ I + A
Sbjct: 192 TAFLLGEIVKKAGLPAGVLNIVHGLGGSCGQAIVAHPGIKAISFTGGTTTGEHIARTAAP 251
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
K+++LELGGK+P II D + + + F +QGQIC+ SR+ V+ +Y+KF
Sbjct: 252 M-FKKLSLELGGKNPNIIFADCNYDKMLTTTLRSSFANQGQICLCGSRILVEQSLYEKFK 310
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGAN--LLAGGERI--- 361
V + ++VG+P T G + + +K+L I K +L+GG +
Sbjct: 311 TDFVARVQQLKVGHPNQSDTKVGAVVSAAHRDKILDYIAFAKANPKEYTILSGGNSVLIE 370
Query: 362 -GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GYY++PTV ++D + +EEIFGPV +I+ F + ++ AN T YGL+A ++T
Sbjct: 371 GHEGGYYLEPTVIEVQSNDCKLNQEEIFGPVVTIIPFKDEAQALELANGTRYGLSATLWT 430
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
++L+ ++ S +EAG VWVN +L + PFGG KDSG+GRE G +A+ + E K V I
Sbjct: 431 SDLSRTMRMSNELEAGIVWVNTWLNRDLRTPFGGVKDSGVGREGGFEALNFFTEPKNVCI 490
>UniRef50_A0G7A9 Cluster: Aldehyde dehydrogenase; n=8; Bacteria|Rep:
Aldehyde dehydrogenase - Burkholderia phymatum STM815
Length = 525
Score = 299 bits (734), Expect = 1e-79
Identities = 157/341 (46%), Positives = 210/341 (61%), Gaps = 9/341 (2%)
Query: 144 QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKG 203
QP+GV GLI PWN K+ ALAAGCT VVKP+E + L +A +P G
Sbjct: 186 QPLGVAGLITPWNSNAGFICGKLAAALAAGCTAVVKPSEMSALQTQIVTQALHDADLPPG 245
Query: 204 VVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLI 263
V NIV G G+ G ++ HPDVAKISFTGS VGK I + G + LKRVTLELGGKSP++
Sbjct: 246 VFNIVTGRGDSVGAQISSHPDVAKISFTGSTAVGKTILR-TGADTLKRVTLELGGKSPVV 304
Query: 264 IMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFD 323
+++DA+ A+P A F + GQ C+A +R+ V +F + + G+P D
Sbjct: 305 VLDDAEFAQAVPLAIQAGFMNSGQACIAGTRILVPRPRLAEFEALVRDEVARTQSGDPRD 364
Query: 324 ESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG---TAGYYIQPTVFADVNDDM 380
T GP + + +V I G EGA L+AGGE AG++I+PTVF+DV +DM
Sbjct: 365 PRTTVGPMVSQKQWERVQRYIRIGIDEGARLIAGGEGRPDGVAAGWFIRPTVFSDVTNDM 424
Query: 381 TIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWV 440
TIA+EEIFGPV +I+ +D +E+ + AN+TNYGL A +F+ + A + +EAG V V
Sbjct: 425 TIAREEIFGPVLAIIAYDDVEQAVAIANDTNYGLQAYVFSQDTTRARDVASRIEAGRVLV 484
Query: 441 NNYLTMAHQ--APFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
N T+AH+ APFGGFK SGIGRE G +EA+LE K V+
Sbjct: 485 N---TLAHEPAAPFGGFKQSGIGREYGTYGIEAFLEPKAVL 522
>UniRef50_O59808 Cluster: Probable betaine aldehyde dehydrogenase;
n=1; Schizosaccharomyces pombe|Rep: Probable betaine
aldehyde dehydrogenase - Schizosaccharomyces pombe
(Fission yeast)
Length = 500
Score = 299 bits (734), Expect = 1e-79
Identities = 167/458 (36%), Positives = 247/458 (53%), Gaps = 8/458 (1%)
Query: 10 LFIDNEWVDAKD--GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
LFID ++V + + +P +I A F R+ W
Sbjct: 23 LFIDGKFVSPIEPAAKPIPLINPATEEIIGTCANASAKDVDSAVENAYNTF-RSGIWAKW 81
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
QRG +L K A ++ E LA +++ + G L + D Y +A+
Sbjct: 82 PGKQRGLVLRKIAKMMREKRELLAGIDTINCGKPTPYALFDIDSCADMFEYYAEVAETDN 141
Query: 128 GDT---IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
+P + ++ + P GV G+I PWN P+ M L K+V A+A+G VV+KP+E
Sbjct: 142 PTVKVPLPNNPGFCAFEKRFPRGVIGVITPWNFPLKMALWKLVPAIASGNCVVLKPSELA 201
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P + KEAG+P GV+N++ G G+++G AL+ HP +A ++FTGSL GK I AA
Sbjct: 202 PWSCLEFALICKEAGLPDGVLNVIIGSGKESGAALSCHPKIAYLAFTGSLATGKKIMHAA 261
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
N+ +TLELGGKSPLII DADL+LAIP A +FF+QG+ C AASRL V + D+
Sbjct: 262 -AENIVPLTLELGGKSPLIICEDADLSLAIPSAAFAIFFNQGEACTAASRLIVHESVADE 320
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-ERIGT 363
+ G V A + +GN D GP + ++ K++ I++ EG + GG R
Sbjct: 321 VLGGLVSEANKLIIGNGLDPQVTLGPVVSKTQFEKIVSYIQSAINEGCKCVVGGLPRSEQ 380
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GY+I PTVF +V I +EEIFGPV ++ F T EE ++ AN++ YGL +G+F+TN
Sbjct: 381 KGYFIPPTVFTNVQTHNKIWREEIFGPVLAVKTFHTNEEALELANDSEYGLGSGVFSTNP 440
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIG 461
FS ++EAG +NNY + H+ P+ G+K SG+G
Sbjct: 441 KTLEFFSNNIEAGMCSLNNYHVVTHELPWIGWKHSGLG 478
>UniRef50_Q7QBI1 Cluster: ENSANGP00000016555; n=7; cellular
organisms|Rep: ENSANGP00000016555 - Anopheles gambiae
str. PEST
Length = 523
Score = 299 bits (733), Expect = 1e-79
Identities = 158/474 (33%), Positives = 255/474 (53%), Gaps = 7/474 (1%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
+K ++ +++ W+ A+ G TFD +P +G+V+ V F W
Sbjct: 41 LKQSQAYVNGSWIGARSGATFDVQNPANGAVLGAVPDMARDDVQLAIDAAYDAFYE-PRW 99
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
+ A +R LL + L+E++ + +A + + ++G L ++ V + A
Sbjct: 100 HNSTAKERAALLKNWHALMEKNRQEIASIMTAESGKPLVESLGEVAYGNSFVEWFAEEAR 159
Query: 125 KIQGDTIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+I G+ +P+ + + + PVGV GLI PWN P M K A+AAGCTVV+KPAE
Sbjct: 160 RIYGEIVPSPVANRQIMMTRNPVGVAGLITPWNFPHAMITRKAAAAIAAGCTVVIKPAED 219
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPG---FGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
TPLT +EAG PKGV+N++ + G L VA ISFTGS EVGKL+
Sbjct: 220 TPLTALALARLAEEAGFPKGVINVITSSRTHAAEIGQLLCGSDKVAAISFTGSTEVGKLL 279
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
+ + +KR+ LELGG +P I+ AD+ A+ A + F + GQ C++A+R +Q
Sbjct: 280 YRQCA-DGVKRIGLELGGNAPFIVFKSADMEKALTGAMNSKFRNCGQTCISANRFLIQDE 338
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
++D+FV +E + + +G+ + GP I+++ + KV ++ K +GA + GG+
Sbjct: 339 VHDEFVAKLIERIRKLAIGDGSRDGVQIGPLINQAQLKKVDQFVQDAKDKGAKVHTGGKT 398
Query: 361 IGTAG-YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
+ G Y +PTV D+ D+M + EE+FGPV S+++F T E + AN T GLA F
Sbjct: 399 LPELGPLYYEPTVVTDLRDNMLLYNEEVFGPVVSVVRFKTEAEALAIANGTRRGLAGYFF 458
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
+ +LN + ++ +E G + +N L A +A FGG K+SGIGRE ++ Y+
Sbjct: 459 SNDLNQVFRVARQLETGMIGINEGLISATEAAFGGIKESGIGREGSRHGIDEYV 512
>UniRef50_A1UC91 Cluster: Betaine-aldehyde dehydrogenase precursor;
n=13; Actinomycetales|Rep: Betaine-aldehyde
dehydrogenase precursor - Mycobacterium sp. (strain KMS)
Length = 523
Score = 298 bits (731), Expect = 2e-79
Identities = 164/474 (34%), Positives = 246/474 (51%), Gaps = 10/474 (2%)
Query: 12 IDNEWVDAKD----GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
+ + W+D G +F +P G+V+ + A+ W A
Sbjct: 30 VASSWIDGAPVQTGGGSFQIVNPATGAVVTEYARAANVDVDVAVAAARAALPG---WATA 86
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKI 126
++R +L K A L + + L E G + + G D++ + A +
Sbjct: 87 TPAERSAVLAKLAKLADEHTDVLVAEEVSQTGKPVRLAREFDVPGSVDNIDFFAGAARHL 146
Query: 127 QGD-TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
+G T GD S ++ +GV I PWN P+ M + KV+ ALAAGCTVV+KP E TP
Sbjct: 147 EGKATAEYSGDHTSSIRREAIGVVATITPWNYPLQMAVWKVLPALAAGCTVVIKPCELTP 206
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT EAG+P GV+N+V GFG D G AL HP V ++FTGS VG+ + AA
Sbjct: 207 LTTLTLARLAGEAGLPPGVLNVVTGFGADVGTALAGHPGVDLVTFTGSTVVGRKVMSAAA 266
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+ R LELGGK+P ++ +DADL+ AI A +G + GQ C AA+R V +YD F
Sbjct: 267 VHG-HRTQLELGGKAPFVVFDDADLDAAIQGAVAGSLINSGQDCTAATRAIVARDLYDDF 325
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
V G E I VG+P D T GP I + +KV G++ EG ++ GG G
Sbjct: 326 VAGVAEVMGKIVVGDPEDPDTDLGPLISTAHRDKVAGMVSRAPAEGGRVVTGGTIPDLPG 385
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
+ +PT+ ADV + + +EEIFGPV ++ F ++ + +AN+T+YGLAA +T ++
Sbjct: 386 SFYRPTLIADVGEQSEVYREEIFGPVLTVRSFTDDDDALRQANDTDYGLAASAWTRDVYR 445
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
A + S+ + AG VW+N+++ + + P GG SG G++ + E YL K V+
Sbjct: 446 AQRASREINAGCVWINDHIPIISEMPHGGVGASGFGKDMSDYSFEEYLTIKHVM 499
>UniRef50_Q9UTM8 Cluster: Succinate-semialdehyde dehydrogenase; n=1;
Schizosaccharomyces pombe|Rep: Succinate-semialdehyde
dehydrogenase - Schizosaccharomyces pombe (Fission
yeast)
Length = 493
Score = 297 bits (730), Expect = 3e-79
Identities = 163/476 (34%), Positives = 252/476 (52%), Gaps = 8/476 (1%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
+ + F+ +W+ + + +TF+ +P G +I KVA F+ +
Sbjct: 17 HAQSFVQGKWISSPNNKTFEVDNPATGEIIGKVADVSVEETKKAISAANEAFKTYKNFTH 76
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKI 126
QR +LL ++A+LI + + L K+ + +NG ++ +++ + A +
Sbjct: 77 V---QRSQLLERWAELIMENKDDLVKMLTLENGKPLSQAEMEVTTCSGYLKWYAAEAVRT 133
Query: 127 QGDTIPTD--GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
GD P+ +F ++KQPVGV LI PWN P M K ALAAGCT + PA +T
Sbjct: 134 FGDVAPSSLQSQNFLISIKQPVGVSALITPWNFPAAMIARKGGAALAAGCTAIFLPAFRT 193
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDA-GVALTHHPDVAKISFTGSLEVGKLIQKA 243
P +EAG P GV+N++ A G LT +P V K+SFTGS VGK++
Sbjct: 194 PYVCLGLVRLAQEAGFPDGVLNVITSSDASAHGKELTTNPIVRKVSFTGSTNVGKILM-G 252
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K+V++ELGG +P I+ D ++ A+ + F GQ+CV +R+YV +YD
Sbjct: 253 QSASTIKKVSMELGGNAPFIVFPDFPIDQAVESFCTIKFNSCGQVCVCPNRVYVHKNVYD 312
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV E K I+VG+ FD S+ GP I + KV IE +GA + GG+ I +
Sbjct: 313 EFVSKLTEKVKTIKVGDGFDSSSAVGPLISQDGCKKVSKHIEDAVSKGAKITVGGKEISS 372
Query: 364 A-GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ GY+ +PTV + V DM +A EE FGP+ S+ KFD EEVI+ AN+++ GLA +FT N
Sbjct: 373 SKGYFFEPTVLSGVTQDMLVASEETFGPLASVFKFDDTEEVIEWANDSDVGLAGYVFTNN 432
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
L+ + +K +E G V N + FGG K SG G+E G V+ ++ K +
Sbjct: 433 LSTMIHVAKELEVGLVGANIEMVDEPFISFGGIKQSGFGKEAGRLGVQEFMVVKEI 488
>UniRef50_Q97BQ6 Cluster: Betaine aldehyde dehydrogenase; n=2;
Thermoplasmatales|Rep: Betaine aldehyde dehydrogenase -
Thermoplasma volcanium
Length = 498
Score = 297 bits (730), Expect = 3e-79
Identities = 174/461 (37%), Positives = 245/461 (53%), Gaps = 15/461 (3%)
Query: 29 SPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIERDFE 88
SP DGS IA V + + W S+R KLL K AD I+ E
Sbjct: 26 SPVDGSPIASVYFADRDAVSKAIDSSYDSYYK--VWSKFTLSERKKLLAKLADRIQEKSE 83
Query: 89 YLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD-----TIPTDGDSFSYTLK 143
A LES + G + + L IP + +L A + + T P DS
Sbjct: 84 RYATLESLNTGKTLRQSM--LMDIPLGIEHLRYFATETEFKMERQITHPEYPDSHGIVQY 141
Query: 144 QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKG 203
P+GV G I PWNVP LM + K AL AG TVV+KP+ TPLT G P G
Sbjct: 142 VPMGVVGAITPWNVPFLMAVWKAAPALLAGNTVVIKPSSFTPLTTIEMARDAISVGFPPG 201
Query: 204 VVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLI 263
V+N+V G GE G L + V +SFTGS GK I + G +K+VTLELGGKSP I
Sbjct: 202 VLNVVNGRGETVGEELARNKKVRMLSFTGSTYTGKRITEITG---IKKVTLELGGKSPNI 258
Query: 264 IMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFD 323
+ +DADL A G++ + GQ+C + SRL VQS I DKF+ + +R GNP
Sbjct: 259 VFDDADLERAALGVMFGIYLNSGQLCESGSRLLVQSSIKDKFLNLLKSKIEKMRPGNPMS 318
Query: 324 ESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA---GYYIQPTVFADVNDDM 380
T ++ +K+ ++ +G K+G+ + G+ G Y PT+ V++DM
Sbjct: 319 METDISAITTKNQRDKIEKMVNSGLKDGSVIFYQKSIDGSVPKGGLYFPPTILDKVSEDM 378
Query: 381 TIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWV 440
+AKEEIFGPV S+++FD + ID+AN T+YGLAAG++T + A + + +EAGTVW+
Sbjct: 379 EVAKEEIFGPVLSVMEFDDEADAIDKANMTDYGLAAGVWTQDSEKATRVASSIEAGTVWI 438
Query: 441 NNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
N Y ++ AP GGFK+SG+GRE G+ + + + + + +S
Sbjct: 439 NEYHLLSAAAPRGGFKNSGVGRELGLDGIMEFTQTRHLFVS 479
>UniRef50_A0W6P7 Cluster: Salicylaldehyde dehydrogenase; n=1;
Geobacter lovleyi SZ|Rep: Salicylaldehyde dehydrogenase
- Geobacter lovleyi SZ
Length = 483
Score = 297 bits (729), Expect = 4e-79
Identities = 171/479 (35%), Positives = 259/479 (54%), Gaps = 13/479 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+++I+ W D+ DG FD F+P+ G ++ VA G F +W
Sbjct: 6 QMYINGTWQDSADGSWFDDFNPYTGEILTTVANGSQQDALLAVNAAADAFP---DWAAVA 62
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
SQ+ L K ADL+E+ + L L + + G + P+ +R GS A ++ G
Sbjct: 63 PSQKRLLFLKAADLLEKRKDELIDLLARETGAARPFAAYQAAAGPNYLREAGSQAHRVTG 122
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
+P++ S ++ PVGV I PWN P+++ L V A+A G TVV+KP+E++P++
Sbjct: 123 TILPSETTKVSMVMRHPVGVVAGISPWNCPVVLSLRAVCFAMAYGNTVVLKPSEESPVSG 182
Query: 189 XXXXXXX-KEAGIPKGVVNIVP-GFGEDAGVALTHHPD--VAKISFTGSLEVGKLIQKAA 244
+EAG PKGV NIV G+G + V D V +ISFTGS VG+ + +
Sbjct: 183 GILLAELFEEAGFPKGVFNIVTHGYGRSSEVGDLFIQDRRVKRISFTGSTRVGRELAEKC 242
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G +LKR+ LELGG PLI++NDAD++ A+ A G F HQGQ+C+ A RL ++ + +
Sbjct: 243 G-RHLKRIALELGGNDPLIVLNDADMDHAVNAAIFGRFLHQGQVCMNAKRLIIEKTVAQE 301
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
F V A++VGNP D +TV GP I+ + G + EGA LL GG G
Sbjct: 302 FTARFVARTSALKVGNPLDAATVIGPLINHKQYETLEGQVNRAVAEGAELLCGG--YGN- 358
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G PTV +V +DM+I EE FGPV I+ + ++ + AN++ YGL+AGI T N+
Sbjct: 359 GLCYHPTVLGNVREDMSIFHEETFGPVAPIIVAEDADDALRLANSSAYGLSAGILTNNMQ 418
Query: 425 NALQFSKHVEAGTVWVNNY-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L ++ +E+G VN+ L AP GG +SG G+ GI+A+ + E++ V + +
Sbjct: 419 QGLALARRIESGACHVNDSPLYGETHAPLGGVNNSGWGK-FGIEAMHEFTEQQWVTLEM 476
>UniRef50_Q6NER7 Cluster: Betaine aldehyde dehydrogenase; n=31;
Bacteria|Rep: Betaine aldehyde dehydrogenase -
Corynebacterium diphtheriae
Length = 525
Score = 297 bits (728), Expect = 6e-79
Identities = 176/489 (35%), Positives = 247/489 (50%), Gaps = 18/489 (3%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
K L+I+ W A GE +P DGSV+ V++ F R EW
Sbjct: 25 KPATLYINGTWQPADSGEVRTITNPADGSVVGVVSEAGEHDTERAIAVARETFDRG-EWL 83
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
A +RGK+L K L+ + A+ ES D G + I ++ Y G+LA
Sbjct: 84 AVPAVERGKILLKVGALLREHKDEFARAESADTGKRLAESELDMDDIANAFDYFGTLAQH 143
Query: 126 IQGDTI-PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G + P D + S +PVGVCGLI PWN P+L KV ALAAG T V+K AE T
Sbjct: 144 EAGRVVDPGDPNVRSRIDVEPVGVCGLITPWNYPLLQVSWKVAPALAAGNTFVLKQAELT 203
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P T + AG+P GV N++ G G + G L+ P V +SFTG L G+LI + A
Sbjct: 204 PHTAMMLMTLFERAGVPAGVANLITGAGANCGNPLSTSPLVDMVSFTGGLVTGRLIARNA 263
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+KRV LELGGK+P +I DAD + A+ A +G F H GQ+C A SR+ V+ I+D+
Sbjct: 264 -AETVKRVALELGGKNPNVIFADADFDAAVDNALNGAFVHSGQVCSAGSRIVVEESIHDR 322
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG------ 358
FV+ A I++G P D + GP I +KV + K++GA + GG
Sbjct: 323 FVEELTRRAAQIKLGGPLDTAAETGPLISLEHRDKVDAYVVAAKEQGATITTGGRVADAS 382
Query: 359 ERIGT---------AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANN 409
+ G+ AG + PT+ + DM +E FGP ++ F T EE I AN+
Sbjct: 383 DNEGSHATGNTDLAAGAFYLPTIIDNCTRDMDCVHDEAFGPTVTVETFRTEEEAIAIAND 442
Query: 410 TNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAV 469
T YGLA ++T + A + ++ + GT+W+N++ QA +GG K SG GRE G +
Sbjct: 443 TEYGLAGAVWTQDAGKAERVARKLRHGTIWINDFHPYLPQAEWGGMKQSGNGRELGPTGL 502
Query: 470 EAYLEEKTV 478
Y E K V
Sbjct: 503 AEYQEHKHV 511
>UniRef50_Q0SDD4 Cluster: Aldehyde dehydrogenase; n=6;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 480
Score = 297 bits (728), Expect = 6e-79
Identities = 172/481 (35%), Positives = 259/481 (53%), Gaps = 11/481 (2%)
Query: 5 IKYTK--LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
+KYT+ LFID W + SP + A R
Sbjct: 1 MKYTRSHLFIDGRWHTPSTSDRITVISPTTEEPVGS-APDSTPADVDAAVSAARRALRAP 59
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRIL-SGIPDSVRYLGS 121
EW + ++R LL +FAD ++R A + + +NGM L SG ++RY
Sbjct: 60 EWSELEPAERADLLRRFADALDRRRIDTAAIVTDENGMPAAISLAAEGSGPAATLRYYAD 119
Query: 122 LADKIQGDT--IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
L +K +T I +G S + ++P+GV I+PWN P + + K+ ALA+GCTVV+K
Sbjct: 120 LTEKTPVETPRIAANGRSTTIVRREPIGVVAAIIPWNFPQSLTMFKLAPALASGCTVVLK 179
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
PA +T L +EAG+P GV+NIV G G + G L HP+V KI+FTGS G++
Sbjct: 180 PAPETVLDAFQLADAAEEAGLPGGVLNIVTG-GREIGAYLVAHPEVNKIAFTGSTAAGRV 238
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I + G L+ VTLELGGKS II++DADL + GQ C +SR+
Sbjct: 239 IGETCG-RLLRPVTLELGGKSAAIILDDADLVSVARGLSWASLLNNGQTCYLSSRILAPR 297
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
Y + V A + VG+P D +T GP + E V I+TG++EGA + AGG
Sbjct: 298 SRYRETVDAVAHLASELVVGDPADPATRVGPLVSERQRRSVEAYIDTGRREGATVAAGGG 357
Query: 360 RIG--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
R G++++PTVFAD+++ T+A+EEIFGPV ++L +D L++ + AN++ YGL
Sbjct: 358 RPKHLDRGWFVEPTVFADLDNSATVAREEIFGPVLTVLPYDDLDDAVAIANDSEYGLGGT 417
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
++T++ L ++ +E G+V V N+ + APFGG K SG+GRE G + ++AY+ K+
Sbjct: 418 VWTSDPEKGLDLARRIETGSVGV-NFFDLDIGAPFGGVKASGLGRELGPEGLDAYVRTKS 476
Query: 478 V 478
+
Sbjct: 477 M 477
>UniRef50_Q0SCN9 Cluster: Aldehyde dehydrogenase; n=2;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 503
Score = 296 bits (727), Expect = 7e-79
Identities = 168/469 (35%), Positives = 252/469 (53%), Gaps = 15/469 (3%)
Query: 18 DAKD--GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKL 75
DA D G D P VIA V +G ++W +R L
Sbjct: 38 DAVDNSGPRTDVVDPSTEQVIAAVPQGTAADVDRAVAAAVAA---KNDWARLVPKERSLL 94
Query: 76 LYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG 135
L++ AD IE++ E LA+LES + G ++ ++G D+ R++ A ++ T G
Sbjct: 95 LHRIADRIEQNSEVLARLESANTGKPFEVSNDDVAGTVDTFRFM---AGALRATTSMAAG 151
Query: 136 D----SFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXX 191
D S L++P+GV G++ PWN P+LM K+ LAAG TVV+KP+EQTPLT
Sbjct: 152 DYAENHLSVILREPLGVVGVVTPWNYPLLMAAWKIAPILAAGNTVVIKPSEQTPLTTLKF 211
Query: 192 XXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKR 251
+ +P GV N+V G G G LT HPDV ++ TGS+ GK + + A + LKR
Sbjct: 212 AELVGDL-LPVGVFNVVSGLGPTVGARLTEHPDVDMLALTGSVGSGKAVARGAA-DTLKR 269
Query: 252 VTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVE 311
V LELGGK+P++I DADL+ A + +++ GQ C AA R+ V + ++F + VE
Sbjct: 270 VHLELGGKAPVVIFADADLDDAAVSLRAASYWNSGQECGAACRILVHESVAEEFTRKLVE 329
Query: 312 YAKAIRVGNPFDESTVN-GPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
VG P TV GP + ++ +V +E ++G GG + GY++ P
Sbjct: 330 QVSTFVVGEPGAGDTVEIGPLVSKAHFERVTAYLERAAQQGITAAIGGSALDGPGYFVAP 389
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV V D A+EEIFGPV ++ F +E RAN+ +GL+A ++T N + + +
Sbjct: 390 TVLVGVPDGAECAREEIFGPVVTVETFTDEDEATRRANDVPFGLSASVWTENARRSHEVA 449
Query: 431 KHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++AGTVWVN++L +A++ P+GGFK SG GR+ I A++ Y K V+
Sbjct: 450 ARIDAGTVWVNSHLVLANEVPWGGFKGSGYGRDLSIYALDDYSRTKHVM 498
>UniRef50_A7UBP5 Cluster: Putative aldehyde dehydrogenase; n=1;
Paracoccus methylutens|Rep: Putative aldehyde
dehydrogenase - Paracoccus methylutens
Length = 504
Score = 296 bits (727), Expect = 7e-79
Identities = 175/481 (36%), Positives = 264/481 (54%), Gaps = 13/481 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+ I W A GET +P S I +V + + F W A
Sbjct: 20 MLIGGAWQAAASGETITVENPARRSPIGEVPRARAEDVDRAVQAAAAAFPA---WARIPA 76
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSG-IPDSVRYLGSLADKIQG 128
+RG+LL + +E E LA+ S + G + R + + D+ RY G LA +++G
Sbjct: 77 RERGRLLAGIGEALEARLEELARTISAETGNALRTQARGEARMVADAFRYFGGLAGELKG 136
Query: 129 DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
TIP SYT ++P+GV G I+PWN P + K+ A+ AG T+V+K AE PL
Sbjct: 137 LTIPLGEGVLSYTRREPIGVTGAIVPWNAPAQLAALKIAPAICAGNTIVLKAAEDAPLAV 196
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
++ +P GVVN+V G+GE+ G L HP V K+SFTGS VGK I +AA ++
Sbjct: 197 LLIAEICQQH-LPPGVVNVVTGYGEECGAPLAGHPLVRKVSFTGSTGVGKAIMRAA-SDR 254
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIP-YAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
L V+LELGGKSP ++ DAD + + S F Q Q C A SRL++ + I++ F++
Sbjct: 255 LAPVSLELGGKSPSVVYEDADEDWVVDGIIASMRFTRQSQSCSAGSRLFLHADIFEPFLE 314
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETG-KKEGANLLAGG--ERIG-- 362
V A+++G+P DE+T G I+E K+ G +E G + A L+ GG R G
Sbjct: 315 KLVARTSALKIGDPLDEATDIGAIINERQFKKICGYVEEGLDRSEARLVMGGLPPREGPL 374
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ GY+ PT+FAD +++ +A+EEIFGPV + + E I AN+++YGLAA ++T +
Sbjct: 375 SEGYFALPTIFADTSNEWRLAREEIFGPVLVAIPWRDEAEAIRMANDSHYGLAAYVWTRD 434
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKA-VEAYLEEKTVIIS 481
+ AL+ + +EAG V VN A +GG K+SGIGRE ++ ++++ E K+V +S
Sbjct: 435 IGRALRTAHAIEAGWVQVNQGGGQALGQSYGGVKESGIGREMSLEGMLDSFTETKSVNVS 494
Query: 482 L 482
L
Sbjct: 495 L 495
>UniRef50_Q3W6C9 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Frankia sp. EAN1pec
Length = 493
Score = 296 bits (726), Expect = 1e-78
Identities = 161/479 (33%), Positives = 253/479 (52%), Gaps = 8/479 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I+ W T + SP ++ + + F+ N W A+
Sbjct: 12 YINGTWAAPAGSGTLNVVSPSTEEIVGALPEATREDMDRAVRAARDAFE-NGPWPRMSAA 70
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV-RYLGSLADKIQGD 129
+R +L + A+ + + +A++ + + G +G+ V Y LA + +
Sbjct: 71 ERADILARAAEALRKHEAEIAQVTTDEMGCATSQAKAAQTGLVAPVFEYYSELARSYEFE 130
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
GD + ++PVGV I+PWN P+ + K ALAAGCTVV+KPA + PL+
Sbjct: 131 RTVVAGDRGALVTQEPVGVVAAIVPWNAPVTLAAWKAAPALAAGCTVVLKPAPEAPLSNF 190
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAG+P GVVN+VPG G + G L HPDVAK++FTGS G+ I G +
Sbjct: 191 ILADAMDEAGVPPGVVNVVPG-GREVGEYLVTHPDVAKVAFTGSTAAGQRIMSLCG-EAV 248
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
+RV+LELGGKS I+++DAD + +P G GQ+C A +R+ V Y+K ++ A
Sbjct: 249 RRVSLELGGKSASILVDDADFDTVVPTVVRGGMHLSGQVCGAHTRVLVPRSRYEKVLEIA 308
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--TAGYY 367
A + VG+P D S GP + E +V G IE ++GA ++AGG R G+Y
Sbjct: 309 AAAAAGVSVGDPHDPSVFVGPLVAERQRTRVEGYIEGAVRDGARVVAGGVRPEHLPRGWY 368
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+ PT+ DV+++M IA+EEIFGPV L +D +++ + AN++ YGL+ G+++ + +
Sbjct: 369 VAPTIIGDVDNNMRIAREEIFGPVLCFLPYDDIDDAVRIANDSQYGLSGGVWSADPARGV 428
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
+ ++ + G+V VN PFGGFK SG+GRE G + + +LE ++ I LP L
Sbjct: 429 EVARRIRTGSVAVNGAYPPFPLVPFGGFKQSGLGRELGPEGLAGFLETRS--IGLPAAL 485
>UniRef50_A5V7S3 Cluster: Aldehyde dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Aldehyde dehydrogenase - Sphingomonas
wittichii RW1
Length = 499
Score = 295 bits (723), Expect = 2e-78
Identities = 184/483 (38%), Positives = 264/483 (54%), Gaps = 17/483 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI EW DG D SP G+V A+VA G F N W
Sbjct: 19 RLFIGGEWRAPADGTFLDVVSPATGAVGARVAAGGPKDIEAAVRAARDAFD-NGPWPRMP 77
Query: 69 ASQRGKLLYKFADLI-ERDFE--YLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK 125
++R ++ + L+ ER E + LE + + + + D +G A
Sbjct: 78 IAERAAIVRRIGALLRERLTETTWATTLEMGAPLPMARAVAERAAALFDEYADIGE-AYL 136
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
I+ +G+ + + +PVGV I+PWN P L+ KV AL AGC VV+KPA +TP
Sbjct: 137 IEDVRARANGEH-AVVVSEPVGVVAAIVPWNGPSLLAALKVAPALVAGCAVVLKPAPETP 195
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L + AG+P GV N+VP E + + HH DV KISFTGS VGK I +
Sbjct: 196 LDAYILAECIEAAGVPAGVFNLVPADREASDHLIRHH-DVDKISFTGSTMVGKHILRTTA 254
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV---QSGIY 302
+ + RV+LELGGKS I+++DAD L + + V + GQIC A R+ V Q+ +Y
Sbjct: 255 -DRVARVSLELGGKSAAIVLDDADPELVVSRMATEVTMNTGQICAALMRVIVPRAQAKMY 313
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+ + AV AK IRVGNPF++ T GP + + +V G IE G++EGA L+ GG R
Sbjct: 314 GEMLADAV--AK-IRVGNPFEQGTQVGPLAMKRQLERVQGYIEKGREEGATLMCGGGRPS 370
Query: 363 TA--GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G+YIQPTVFA+V+ MTIA+EEIFGPV S++ D ++ + AN+++YGL G+FT
Sbjct: 371 DLGDGFYIQPTVFANVDHRMTIAREEIFGPVASVIAHDGPDDAVRIANDSDYGLHGGVFT 430
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+++ A ++ + G V +N T+ Q PFGGFK SG+ RE G++ +LE KTV +
Sbjct: 431 RDVDTAYAVARRMRTGNVG-HNIRTIDWQMPFGGFKQSGLSREGGVEGFRNFLEIKTVYV 489
Query: 481 SLP 483
+ P
Sbjct: 490 ATP 492
>UniRef50_Q0CN81 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 490
Score = 295 bits (723), Expect = 2e-78
Identities = 175/487 (35%), Positives = 258/487 (52%), Gaps = 14/487 (2%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
+T+LFI+N++V AK +P+DGS++ R W
Sbjct: 11 HTQLFINNKYVPAKSASRLTVRNPYDGSIVTDDIHCAGEEDVNDAVAAALNASRGP-WSQ 69
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSV-RYLGSLADK 125
+R K + ADL++ + L KLES G+ R + G+ +V RY DK
Sbjct: 70 MPGQERAKRMLALADLLDAHADELTKLESLSIGLPIA-ISRGIGGVIGAVWRYYAGFCDK 128
Query: 126 IQGDTIPTDGDS-FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
+ GD +P D F P GVC I WN + F K+ A+AAG + + K +E++
Sbjct: 129 LPGDFVPEGDDRVFKVVRYDPFGVCAGIGAWNASLFFFSMKIAPAVAAGNSFIFKSSEKS 188
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
PL +AG P GV+N++ G G G L H + +ISFTGS+E GK IQ AA
Sbjct: 189 PLGALQIGELIAKAGFPPGVINLLNGDGS-TGALLASHMGIQRISFTGSVETGKAIQAAA 247
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
+NLKRVTLELGGKSP +I +DA++ A+ YA G H GQICVAASRL V I D+
Sbjct: 248 AQSNLKRVTLELGGKSPSLIFDDANIEEALMYASQGFLVHSGQICVAASRLLVHKSIADR 307
Query: 305 FV---KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGAN-LLAGGER 360
FV K E A A G+P ++T GP +DE ++++ + KK + +L GG
Sbjct: 308 FVAELKARFE-ALASASGDPAQDTTFLGPVVDEGQRDRIMSFLNGTKKAKEDVVLTGG-- 364
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
+ G ++ PT+ + D +EIFGPV + F+T +E ++ AN T YGL++ I+T
Sbjct: 365 -ASKGNFVSPTILVNPPLDSPAWTQEIFGPVVCVRTFETEDEAVEIANATTYGLSSCIYT 423
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGR-ENGIKAVEAYLEEKTVI 479
++ AL+ +K ++A V +N+ + P G+K SG G E G A+ +YL+ KTV+
Sbjct: 424 KDIPRALRLAKRLQAAGVAINSNHQPDYDTPLSGWKQSGNGSYEGGRAAILSYLQAKTVM 483
Query: 480 ISLPKKL 486
I++ KL
Sbjct: 484 INMTAKL 490
>UniRef50_Q9H2A2 Cluster: Aldehyde dehydrogenase family 8 member A1;
n=25; Eukaryota|Rep: Aldehyde dehydrogenase family 8
member A1 - Homo sapiens (Human)
Length = 487
Score = 294 bits (721), Expect = 4e-78
Identities = 173/481 (35%), Positives = 252/481 (52%), Gaps = 19/481 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ K+++LELGGK+P II DA+L+ IP F +QG+IC+ SR++VQ IY +F+
Sbjct: 246 H-CKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFL 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG--ERIGT- 363
K VE + +VG P D G I ++ + KV ++ EGA + G +++
Sbjct: 305 KRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 364 ----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AGY++ PTV D+ D+ EEIFGPV ++ FD+ EEVI+RANN YGLAA ++
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++N+ + +K +++G VW N +L PFGG K SGIGRE + + + E KT+
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 480 I 480
+
Sbjct: 485 V 485
>UniRef50_Q4J9S9 Cluster: Aldehyde dehydrogenase; n=1; Sulfolobus
acidocaldarius|Rep: Aldehyde dehydrogenase - Sulfolobus
acidocaldarius
Length = 493
Score = 294 bits (721), Expect = 4e-78
Identities = 157/429 (36%), Positives = 232/429 (54%), Gaps = 5/429 (1%)
Query: 58 FQRNSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVR 117
F ++ +++ R K+L++ A+ I + + L++L + GM + ++ D
Sbjct: 53 FDKDKNGWVSNYKARDKVLFRIAEKIRGEIQTLSRLLVEEIGMPIRQARVQVNAAADVFE 112
Query: 118 YLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
Y KI + +K+PVGV GLI PWN P+ K+ A+ GCT+V
Sbjct: 113 YYAGFGSKIYDTSKFLPSKDMVQIIKEPVGVVGLITPWNFPLTQSARKLAPAITVGCTIV 172
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
KPA +G+PKG +N++ GE G + + KISFTG G
Sbjct: 173 WKPATYAAGISYQLAKIILSSGVPKGALNVIFDPGEKVGAQIVKSKKIDKISFTGETNTG 232
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
K I A + +LKRV+LELGGK P+I+ +D+DL AI A G + GQ C A SRL V
Sbjct: 233 KWIMSEA-SKDLKRVSLELGGKDPIILFSDSDLKNAIKGAIFGALRNAGQACGATSRLLV 291
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
+ I +K K +++GNP E T GP + + +KV+ IETG KEG LL G
Sbjct: 292 EESIAEKVEMAVSNEIKKLKLGNPLQEDTDIGPVVSKPQEDKVIDYIETGIKEGYKLLVG 351
Query: 358 GERIGTA----GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYG 413
G ++ GY+I+PTVF+DV++ IA+EEIFGPV I+ F EE I AN+ YG
Sbjct: 352 GRKVTDGEFQRGYFIEPTVFSDVDNKSKIAQEEIFGPVLVIIYFKDEEEAISLANDVIYG 411
Query: 414 LAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
L A ++T + A++ S+ + GTVW+N+ T + +GG+K SGIGRE GI+ +E +L
Sbjct: 412 LTASVWTNDYKKAIRVSRELRVGTVWINDVYTQPSEGLWGGYKQSGIGRELGIQGIEDFL 471
Query: 474 EEKTVIISL 482
E K + +L
Sbjct: 472 ETKMLYTNL 480
>UniRef50_Q8BWF0 Cluster: Succinate semialdehyde dehydrogenase,
mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent
succinic semialdehyde dehydrogenase); n=278; cellular
organisms|Rep: Succinate semialdehyde dehydrogenase,
mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent
succinic semialdehyde dehydrogenase) - Mus musculus
(Mouse)
Length = 523
Score = 294 bits (721), Expect = 4e-78
Identities = 171/473 (36%), Positives = 250/473 (52%), Gaps = 11/473 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
F+ W+ A TF + P G+ + VA F + W+
Sbjct: 52 FVGGRWLPAP--ATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAF---NSWKGVSVK 106
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R LL K+ DL+ ++ + LAK+ + ++G K + + + A +I GD
Sbjct: 107 ERSLLLRKWYDLMIQNKDDLAKIITAESGKPLKEAQGEILYSALFLEWFSEEARRIYGDI 166
Query: 131 IPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
I T D LKQPVGV +I PWN P M KV ALAAGCTVVVKPAE TP +
Sbjct: 167 IYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSAL 226
Query: 190 XXXXXXKEAGIPKGVVNIVP---GFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+AGIP GV N++P ++ G L P V+KISFTGS GK++ A
Sbjct: 227 ALAQLANQAGIPAGVYNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAA- 285
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV ++R VQ GI+D FV
Sbjct: 286 NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFV 345
Query: 307 -KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
K A K++RVGN F+E T GP I+E + KV + +GA ++ GG+R + G
Sbjct: 346 TKFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVAKGATVVTGGKRHQSGG 405
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
+ +PT+ ++V DM EE FGP+ ++KFD EE + AN GLA ++ +
Sbjct: 406 NFFEPTLLSNVTRDMLCITEETFGPLAPVIKFDKEEEAVAIANAAEVGLAGYFYSQDPAQ 465
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 466 IWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLEVKYV 518
>UniRef50_P51649 Cluster: Succinate semialdehyde dehydrogenase,
mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent
succinic semialdehyde dehydrogenase); n=34; cellular
organisms|Rep: Succinate semialdehyde dehydrogenase,
mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent
succinic semialdehyde dehydrogenase) - Homo sapiens
(Human)
Length = 535
Score = 294 bits (721), Expect = 4e-78
Identities = 172/476 (36%), Positives = 252/476 (52%), Gaps = 11/476 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T F+ W+ A TF P G+ + VA F R WR
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 115
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R LL K+ +L+ ++ + LA++ + ++G K + + + A ++
Sbjct: 116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVY 175
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD I T D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP
Sbjct: 176 GDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPF 235
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGKLIQKA 243
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK++
Sbjct: 236 SALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHH 295
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ GI+D
Sbjct: 296 AA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 304 KFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
FVK E K +RVGN F+E T GP I+E + KV + +GA ++ GG+R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQ 414
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA ++ +
Sbjct: 415 LGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQD 474
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 475 PAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>UniRef50_Q0SC67 Cluster: Probable aldehyde dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable aldehyde
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 482
Score = 293 bits (720), Expect = 5e-78
Identities = 169/478 (35%), Positives = 260/478 (54%), Gaps = 12/478 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+ +I+ +W +A D E F + A G N W +
Sbjct: 11 QFYINGQWREAVDPELFTIAEAATERPLGVAAMGGPSEIDEAVLAARAALD-NGPWGRST 69
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+R + + +FAD +ER E A+L S NGM+ L I+S V L S+A+ +
Sbjct: 70 PHERAETMRRFADSLERRGESTARLVSQQNGMIRP--LSIISNAAAPVAVLRSMAELAEA 127
Query: 129 DTIPTDGDSFS-YTL--KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
T T S +T+ ++PVGV G I+ WN P L+ + K+ ALAAGCT+V+KPA +T
Sbjct: 128 RTFETRRPSKKGHTIVRQEPVGVVGAIVAWNYPQLLAMAKIAPALAAGCTIVLKPAPETA 187
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L ++AG+P GV+NIV G G AG AL HP V KI+FTGS G+ I +AAG
Sbjct: 188 LDAYVLGEAAEDAGLPPGVLNIVAG-GVRAGEALVAHPGVDKIAFTGSTAAGQAIGEAAG 246
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+LKRV+LELGGKS +++ DADL++ VF + GQ C SR+ V G +
Sbjct: 247 -RSLKRVSLELGGKSAAVVLPDADLDVFARSLDDAVFKNGGQTCTTNSRILVPHGRSQEV 305
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--- 362
+ Y + +G+P D++ GP + + +V I G+ EG L+ GG
Sbjct: 306 LDVLAAYVDDLAMGDPLDDAVTLGPMVSDRHRERVRNYIRLGESEGFQLVRGGAEPPDGL 365
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
T G+++ PT+F V+++ +A+EEIFGPV S++ + + +E + AN+T +GL +FT +
Sbjct: 366 TQGWFVSPTIFGGVDNNSRLAQEEIFGPVISVIPYGSEDEAVRIANDTVFGLGGVVFTED 425
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ L + + +GT+ + NY +M +PFGG K SGIGRE G +A++ YLE +++ +
Sbjct: 426 HEHGLDIASRIRSGTMGI-NYFSMDMGSPFGGVKHSGIGREFGPEALDYYLEYRSIYV 482
>UniRef50_A5VCT2 Cluster: Aldehyde dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Aldehyde dehydrogenase - Sphingomonas
wittichii RW1
Length = 502
Score = 293 bits (720), Expect = 5e-78
Identities = 164/467 (35%), Positives = 244/467 (52%), Gaps = 10/467 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI EW A+ GET P G + ++A+ + + W
Sbjct: 24 LFIGGEWRAAERGETLPVTDPSSGDEVGRIAQASPADVDAAVQAARRALE-DPAWARMRP 82
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQG 128
QR +++ + ADLI + LA++E+ ++G + N + + ++RY+ A K+ G
Sbjct: 83 HQREEIMLRLADLIRDEAGSLAEIETVNSGKLIANTRLFDADLSVHTLRYMAGWATKLHG 142
Query: 129 DTIPTDGDSF------SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
+T+ +T + PVGV I PWNVP+ + K+ LA GCT+++KP+E
Sbjct: 143 ETMDLSVPYLPNLRFNGFTRRFPVGVVAAITPWNVPLCQAVWKLAPVLATGCTIILKPSE 202
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
T LT AG+P GVVN+V G GE G AL HP V KI+FTGS VG+LI +
Sbjct: 203 LTSLTALRLAELCDAAGVPPGVVNVVTGTGEVTGRALIEHPGVDKINFTGSTRVGQLIAE 262
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
A + K LELGGKSPLII DADL AIP A ++ + GQ C A SR + +
Sbjct: 263 QA-ARSFKHYNLELGGKSPLIIAEDADLEKAIPGAAWAIYGNSGQNCCAGSRALIHERHF 321
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D V G E A +IR+G D +++ GP + +V G ++ ++ GA ++ GGE +
Sbjct: 322 DAVVAGVAEIAASIRLGPGLDPASMMGPLVSADHRARVAGHVDRAREAGARVI-GGEIVE 380
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+AG Y P V ++ ++EIFGPV F EE + AN+T +GL A I+T
Sbjct: 381 SAGSYFTPAVITGLDHGHPTVQQEIFGPVLCAFPFKDDEEALRIANDTAFGLGASIWTEG 440
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAV 469
L A ++ + ++ GTVW+N + + PFGG K SG+G E G + +
Sbjct: 441 LRTANRYFERLKTGTVWINTHNILDLSLPFGGAKQSGVGFELGHEGI 487
>UniRef50_Q3K7P7 Cluster: Betaine-aldehyde dehydrogenase; n=9;
Proteobacteria|Rep: Betaine-aldehyde dehydrogenase -
Pseudomonas fluorescens (strain PfO-1)
Length = 483
Score = 293 bits (719), Expect = 7e-78
Identities = 174/480 (36%), Positives = 258/480 (53%), Gaps = 14/480 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
L+I+ +W + E +P +++ V G F+ W
Sbjct: 11 LYINGQWSAGR--EHLRVINPATEALLTTVNGGDESAVHQAVTAATEAFKA---WSKTTG 65
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG- 128
++R +L A+ + E+L L+S +NG + + + Y LA+ +
Sbjct: 66 AERASILRNIANGVRNGREHLMNLQSSNNGKPQFEAGIDVDDVIATFEYYAELAEGLDAK 125
Query: 129 --DTIPTDGDSFSYTLK-QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
+P D FS L+ +P GV GLI+PWN P++ K+ ALAAGC VV+KP+E TP
Sbjct: 126 LDSNVPLPSDDFSARLRREPCGVVGLIVPWNFPMVTTAWKLAPALAAGCCVVLKPSEVTP 185
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG-KLIQKAA 244
L E+G+PKGV N+V G G G L+ P +AK+SFTGS VG +++Q+AA
Sbjct: 186 LPELELATIIAESGLPKGVFNLVCGTGLAVGAPLSADPRIAKVSFTGSNAVGVQVMQRAA 245
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
T +K V+LELGGKS L+I+ DADL+LA+ A G FF+ GQ+C A SR+ V + D+
Sbjct: 246 ET--VKGVSLELGGKSSLLILEDADLDLAVELACGGGFFNAGQMCSATSRVLVADELADE 303
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG-- 362
F+ +A+ IRV +PFD G ++++ +VLG I+ G GA L+ GG R
Sbjct: 304 FLIRLKAHAEKIRVADPFDPEVEMGALVNQAQYQRVLGHIDRGLSAGAKLICGGNRPADL 363
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPT+F +V D + EEIFGPV + F T E I AN++ +GL A + T N
Sbjct: 364 PRGYFLQPTIFTEVPLDSALWCEEIFGPVICVRSFATEAEAIALANDSQFGLVASVVTRN 423
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + + ++AG VW+N + Q +GG+K S IGRE G + A+ E K VI +L
Sbjct: 424 AETADRVANALQAGLVWLNAPQVIFPQTAWGGYKQSSIGRELGPWGLAAFQEIKHVIRAL 483
>UniRef50_Q1AV69 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Aldehyde dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 481
Score = 293 bits (719), Expect = 7e-78
Identities = 163/479 (34%), Positives = 246/479 (51%), Gaps = 11/479 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L + E V A+ G +P V+ V KG +EW D
Sbjct: 3 QLLVGGERVSARGGGEMPVVNPATEEVVDTVPKGTAEDVEAAVAAAKGAL---AEWSGKD 59
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+R ++ ++ +A+L + G + L + + LA K++G
Sbjct: 60 PDERAAIMRAGIGAVKERGREIAELLVREQGKPLSEAMGELHHFIHGMDFYADLASKVRG 119
Query: 129 DTIPTD---GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
P G S+ +K+PVGVC I+P+N P+ + KV ALA G TVVVKPAE TP
Sbjct: 120 AYAPLPSSLGKSYGMVIKRPVGVCAAIVPFNFPLTLMGTKVGPALAGGNTVVVKPAETTP 179
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L EAG+P GV N+V G G + G AL HPDV +++FTGS EVG+ I + AG
Sbjct: 180 LATLRVAELFAEAGLPAGVFNVVTGEGPEVGEALVAHPDVRRVAFTGSTEVGRRIMELAG 239
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
KRV++ELGG P+I+ DAD++ A+ G FF+ GQ C+AA R+YV +YD+F
Sbjct: 240 P-QFKRVSVELGGSDPVIVCPDADVDAAVKGVNIGRFFNAGQACLAAKRVYVFDEVYDEF 298
Query: 306 VKGAVEYAKAIRVGNPFDESTV----NGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
++G ++ +G+ ++ GP ++V +E GA ++ GE
Sbjct: 299 MEGLIKRVSRYELGDGLTKAEKPKIRMGPMNSARYRDQVASQLEEALGRGARVVYQGEWG 358
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G GY+ P V D + +EE FGP+ + + L+E + AN++ YGL + I+T
Sbjct: 359 GEKGYFFPPAVIEGAPHDSRVVREETFGPLLPVFRVGDLDEALRLANDSRYGLGSSIWTR 418
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
N+ + ++ +EAG WVN + PFGG KDSG+GRE+G +A+E YLE K+V+I
Sbjct: 419 NIRWIHRAAQEIEAGMTWVNQLHYGYDELPFGGVKDSGVGREHGPEALEYYLESKSVVI 477
>UniRef50_A6VZV8 Cluster: Aldehyde dehydrogenase; n=20;
Proteobacteria|Rep: Aldehyde dehydrogenase - Marinomonas
sp. MWYL1
Length = 500
Score = 293 bits (718), Expect = 9e-78
Identities = 162/463 (34%), Positives = 246/463 (53%), Gaps = 6/463 (1%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
GE D P DG A ++ F++ S W R K++ ++AD
Sbjct: 33 GEKMDVIRPSDGQAYASISIADMDLVDHAVENAWQAFKQ-SNWATQSPRDRAKVMKRWAD 91
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKIQGDTIPTDGDSFSY 140
LI D LA LE+ + + + + +R+ ADK G+ IPT S
Sbjct: 92 LIAADVAVLAPLEAMGSTRPISAATQWDIPFCAEGIRFFAEYADKCGGEVIPTANGSLGM 151
Query: 141 TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGI 200
T+ +P GV G I PWN P++M K+ A+AAG VV+KP+E TP + EAGI
Sbjct: 152 TITEPYGVIGAIAPWNFPLVMASWKIAPAMAAGNAVVLKPSEMTPFSVVRLAELAIEAGI 211
Query: 201 PKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKS 260
P G+ N+V G G G A+ HP ++K++FTGS + G LI KA K VTLELGGKS
Sbjct: 212 PPGIFNVVQGDGL-VGDAICRHPRISKVTFTGSTKTGALIMKACAETGTKPVTLELGGKS 270
Query: 261 PLIIMND-ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVG 319
P ++ +D +++ + + GQ+CVA SRL VQ GI ++ V E + G
Sbjct: 271 PQLVFDDIKNIDKVARRIAGAITTNAGQVCVAGSRLLVQKGIAEQLVSRISEIFSEMVSG 330
Query: 320 NPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG-YYIQPTVFADVND 378
+ ++T P I + ++ G+++ ++G +L GG + ++ PT+ +VN
Sbjct: 331 PTWQDNTTLSPIISAKEVGRIDGVVQRTVQQGGEVLVGGCPLNKDNHFFYTPTILTNVNM 390
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
M ++EIFGPV + F+T +E ++ A++ +YGL+AG+ T +LN A++ K +EAGTV
Sbjct: 391 SMEAVRDEIFGPVLCVETFETEDEALNLASHPSYGLSAGLHTADLNRAMRMVKALEAGTV 450
Query: 439 WVNNY-LTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
WVN Y + P GGFK SGIG++ G A EA + K+V+I
Sbjct: 451 WVNRYGRSWDFAIPTGGFKSSGIGKDLGRYAYEANQKTKSVLI 493
>UniRef50_Q2J3W1 Cluster: Betaine-aldehyde dehydrogenase; n=7;
Proteobacteria|Rep: Betaine-aldehyde dehydrogenase -
Rhodopseudomonas palustris (strain HaA2)
Length = 503
Score = 292 bits (717), Expect = 1e-77
Identities = 170/479 (35%), Positives = 263/479 (54%), Gaps = 13/479 (2%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
I N V A G T + P G+V+ + F W + Q
Sbjct: 29 IGNALVPAVAGATLEVLDPATGAVLGEAPAATTDDVARAVDAASAAFPG---WAATPSRQ 85
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKN-CLRILSGIPDSVRYLGSLADKIQGDT 130
RGKLL + A I LA + + + G + C ++ D V LA +++G+T
Sbjct: 86 RGKLLAEAARAIAAKSGALAAVLALETGKAIRTECRGEIATAIDIVTMYAGLASELKGET 145
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+P D +YT ++P+GV ILPWNVP+++ + K+ AL AG TVVVK +E+ P
Sbjct: 146 LPFDPQILTYTSREPLGVVAAILPWNVPLVLMMLKIAPALVAGNTVVVKASEEAPFATIE 205
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
E +P GV+N++ G G D G AL HP VAK++FTGS VG+LI + A +
Sbjct: 206 MARLMAEL-LPAGVLNVICGTGRDCGSALVEHPAVAKVTFTGSQAVGELIYQTAARKIIP 264
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGV-FFHQGQICVAASRLYVQSGIYDKFVKGA 309
V+LELGGKSP+I+ DAD+ + A +G+ F QGQ C AASR+YV + + D FV
Sbjct: 265 -VSLELGGKSPMIVYPDADMARVVAGAIAGMRFTRQGQSCTAASRIYVHNTLIDAFVAAL 323
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKE-GANLLAGGE--RIGTA-- 364
+ + +G+P DE+T G I + K+ + G++ GA + GE R G
Sbjct: 324 RDAVAKLVIGDPLDEATDIGTVISQRQKAKIESYLALGERTAGAQVARCGELPRAGHLKD 383
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G ++QPT+ + +D + +EEIFGPV + +D ++VI RAN++++GLAA ++T +L
Sbjct: 384 GLFLQPTIVTGLPEDSPLMREEIFGPVVCVQPWDDEDDVIARANDSDFGLAATVWTHDLR 443
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKA-VEAYLEEKTVIISL 482
AL+ + ++AG V VN LT+ +GGF+ SG+G+E ++A +E + ++KTV+I +
Sbjct: 444 TALRAVQRLDAGYVQVNQNLTIQPNLSYGGFRKSGLGKEASLEAMLEHFTKKKTVVIDM 502
>UniRef50_O86001 Cluster: Salicylaldehyde dehydrogenase; n=2;
Novosphingobium aromaticivorans|Rep: Salicylaldehyde
dehydrogenase - Sphingomonas aromaticivorans
Length = 479
Score = 292 bits (717), Expect = 1e-77
Identities = 179/466 (38%), Positives = 252/466 (54%), Gaps = 9/466 (1%)
Query: 17 VDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLL 76
V A G FD +P D SV ++V G + ++ + A+ R +
Sbjct: 13 VAATGGAYFDDLNPVDDSVYSRVPAGTAEDVNRAVENAHQAYLQHRD---LPAAVREGWI 69
Query: 77 YKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGD 136
K A+++ERD A + + G +R + +I+G+TIP+D
Sbjct: 70 AKAAEIMERDTAKFADVLVDEIGSPIAKAGFETRFAVSFLRAAIGVPRRIRGETIPSDTP 129
Query: 137 S-FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX 195
FS +L+QPVGV I P+NVP++ + + ALA G V+ P+E P+
Sbjct: 130 GRFSMSLRQPVGVVAGITPFNVPLIKGIKQSAMALATGNAFVLLPSEAAPMIADLLAKLW 189
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
KEAG+P G+ N+V G G + G LT HP VA I+FTGS VGK I + A NLK+ TLE
Sbjct: 190 KEAGVPDGLFNVVYGNGAEIGDVLTGHPKVASITFTGSSRVGKHIAEIAA-RNLKKYTLE 248
Query: 256 LGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKA 315
LGGKSPL+I DADL+ A+ A +F +QGQ+C+ ASR+YV+ I+D+F K
Sbjct: 249 LGGKSPLVICADADLDKAVNAALFSIFMYQGQVCMGASRIYVERSIFDQFTKAFAAATGR 308
Query: 316 IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFAD 375
G+ D +T+ GP I E ++V I+ + +GA +LAGGE G + T+ +
Sbjct: 309 ANSGDLRDPTTMLGPIISERQRDRVRRHIDDARSKGAAVLAGGEWSGNS---CAATILSG 365
Query: 376 VNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEA 435
V +MT+ +EE FGPV S+ FDTLEE ++ ANNT YGL+A IFT +L+ AL F++ EA
Sbjct: 366 VTAEMTVFEEETFGPVTSLFPFDTLEEALELANNTEYGLSASIFTRDLDKALAFAQRAEA 425
Query: 436 GTVWVN-NYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
G V +N L PFGG K SG GRE +E E K V I
Sbjct: 426 GMVHINAPTLHDEPHVPFGGTKASGFGREGTEADLEIMTEWKWVTI 471
>UniRef50_Q1GJB8 Cluster: Aldehyde dehydrogenase; n=10;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Silicibacter sp. (strain TM1040)
Length = 511
Score = 291 bits (715), Expect = 2e-77
Identities = 156/419 (37%), Positives = 233/419 (55%), Gaps = 5/419 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W AS+RG++L++ I + L++LE+ +G ++ + + + Y
Sbjct: 77 WYAKTASERGRILFEIGRQIRQHAAALSELEALSSGRPMRDTGGEPARMAEMFEYYAGWC 136
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DKI GD IP +YT ++P+GV I PWN P+ +V A+ AG V++KP+E
Sbjct: 137 DKITGDVIPVPSSHLNYTRQEPLGVVAQITPWNAPLFTCCWQVAPAICAGNAVMIKPSEL 196
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT ++AG PKG+VN++ G G +G A+ HP+ A + F GS E G I A
Sbjct: 197 TPLTSVVIGILCEKAGAPKGLVNVIAGDGPGSGQAMIAHPETALVVFVGSAEAGSKIAAA 256
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A + V LELGGKS I+ +DAD++ A+ A + +F GQ CVA SRL V +
Sbjct: 257 AAKRLIPSV-LELGGKSANIVFDDADIDRAVVGAQAAIFASCGQSCVAGSRLLVHRSVQT 315
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER--- 360
+ V+ A I VG+P D +T GP + NK+ +++ + GA++ +GG +
Sbjct: 316 EVVEKLSAAAARIPVGDPMDPATQVGPVNNLRQWNKIDTMVQAATRAGASVASGGGKPAA 375
Query: 361 -IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
+ G++ PTV V M IA EE+FGPV S+L FD EE I AN T YGLA ++
Sbjct: 376 LAASGGFFYAPTVLDAVTPQMEIANEEVFGPVVSVLPFDDEEEAIQLANATPYGLAGAVW 435
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
T ++ A + + V AGT W+N+Y T+ +PFGGF SG GR +G +A+ AY + K+V
Sbjct: 436 TRDVGRAHRVAGAVRAGTFWINSYKTINVMSPFGGFGRSGYGRSSGREALSAYTQTKSV 494
>UniRef50_Q9US47 Cluster: Succinate-semialdehyde dehydrogenase; n=2;
Ascomycota|Rep: Succinate-semialdehyde dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 498
Score = 291 bits (715), Expect = 2e-77
Identities = 163/474 (34%), Positives = 253/474 (53%), Gaps = 7/474 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I +WV A G+TFD +P +A V F +R +D
Sbjct: 27 YIGGKWVTAASGKTFDVENPGLNETLAPVTDMSVEETRKAIKVAHEAFL---SYRNSDIK 83
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R +L ++ DLI + + LA + + +NG + + + + A +I GD+
Sbjct: 84 ERYAILRRWYDLIMENADDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISGDS 143
Query: 131 -IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+ ++ + T+KQPVGV G+I PWN P M KV ALAAGCTVV++PA +TP T
Sbjct: 144 SMSSNPQNRIITIKQPVGVVGIITPWNFPAAMITRKVGAALAAGCTVVIRPAAETPFTAL 203
Query: 190 XXXXXXKEAGIPKGVVNIVPGFG-EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+ AG+P GV+N+V + G+ LT +P + K+SFTGS VGK++ K + ++
Sbjct: 204 ALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQS-SST 262
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
LK+++LELGG +P I+ DADL A + F GQ CV A+R+YV S +YD FV
Sbjct: 263 LKKLSLELGGNAPFIVFEDADLEKAADALMACKFRGSGQTCVCANRIYVHSSVYDAFVDL 322
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG-YY 367
E ++G D +GP I E ++KV +E ++G ++ GG+ G Y
Sbjct: 323 VTERVSKFKLGYGLDAGVTHGPLISEKAISKVKQHVEDAVQKGGVVVTGGKVASNLGPMY 382
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+PTV + M I++EE FGPV ++ KFDT +EV+ AN++ GLA +F+ +++
Sbjct: 383 FEPTVIINAKQGMLISEEETFGPVGALFKFDTEDEVVAWANDSPVGLAGYLFSKDISRVF 442
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+ + ++ G V N L +PFGG K+SG GRE + YL+ K++ IS
Sbjct: 443 RVGEALQVGMVGCNTGLVSDVLSPFGGVKESGFGREGSKYGISEYLDIKSLTIS 496
>UniRef50_A6C3Q3 Cluster: Aldehyde dehydrogenase; n=1; Planctomyces
maris DSM 8797|Rep: Aldehyde dehydrogenase -
Planctomyces maris DSM 8797
Length = 490
Score = 291 bits (713), Expect = 4e-77
Identities = 165/479 (34%), Positives = 255/479 (53%), Gaps = 9/479 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K++ID +WVD + + +P +A++A F + EW D
Sbjct: 7 KMYIDGKWVDGRSETNWTITNPATREPLAEIALANASDVDLAVTAARRAFDKG-EWPRLD 65
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP---DSVRYLGSLADK 125
QRG+LLYK A+ I E LA ++ + G ++ L IP D + L DK
Sbjct: 66 PLQRGRLLYKLAERIRESAEDLAMTDTLNIGKPIRDTLGF--DIPCGADVIESYAGLPDK 123
Query: 126 IQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
I G + D+ + ++P+GV I+PWN P+ K+ LA G TVV+KP+E +P
Sbjct: 124 IAGHSYGGLPDNVTMQFREPMGVIAAIVPWNYPMTNAAIKLAPILACGNTVVLKPSEVSP 183
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L+ +E G P GV+N++ G G +AG AL HP + KI+FTG E G + +AA
Sbjct: 184 LSALMLAKMAEEVGFPPGVINVIHGTGAEAGTALVKHPGINKIAFTGRYETGAQLMEAA- 242
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+ +K V LELGGK+P ++ DA L+ + +G+F H GQICVA SRL V +D+
Sbjct: 243 KDGMKGVLLELGGKTPSVVFPDAPLDHVVNGVITGIFCHLGQICVAGSRLLVHESQHDEL 302
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE-RIGTA 364
++ + A++++ G+P D G + V +E K+EGA L+ G+
Sbjct: 303 LERIIAKAQSLKQGDPTDPEMHLGCLATPTHCGFVRSRVEQAKQEGARLVLSGDISDDPL 362
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
+ PT+F V+ DM +AKEE+FGPV S++ F T EE I AN++++GL A I++T+
Sbjct: 363 DCFYPPTIFDQVSPDMAVAKEEVFGPVLSVMTFKTEEEAIRIANDSDFGLMANIWSTDGT 422
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENG-IKAVEAYLEEKTVIISL 482
AL+ ++ ++AG + +N + P G+K SG G E G I+A + K+VI SL
Sbjct: 423 RALRVARELQAGRISINGGGYLRPNVPIYGYKKSGFGAELGFIEAAHEFCNSKSVIYSL 481
>UniRef50_Q6CK88 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome F of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome F of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 504
Score = 289 bits (710), Expect = 8e-77
Identities = 158/480 (32%), Positives = 259/480 (53%), Gaps = 11/480 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
TK FI+ +W + D F +P G I +V F +R
Sbjct: 29 TKAFINGKWTETDD--KFAVTNPSTGDTIREVTNCGVSDFNKAIEIAHDAF---GTFRQT 83
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+ +R ++L +L+ + + LAK+ + +NG YK+ L + ++ A +I
Sbjct: 84 NVRERAQILDNIYNLMLENKQDLAKILTLENGKPYKDSLGEIVYSAMFFKWFAEEAPRIY 143
Query: 128 GDTIPT--DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
GD IP+ D +T++QP+GV G++ PWN P M K+ +A G T V+KPA +TP
Sbjct: 144 GDIIPSAVSSDQKIFTIRQPLGVIGILTPWNFPSAMIARKLAPVIATGNTCVIKPAHETP 203
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVP-GFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ-KA 243
L+ ++AG+P GV NI+P + G + H V KI+FTGS ++G+L+ ++
Sbjct: 204 LSALALGVIAEKAGLPAGVCNILPTNHTSEIGEYVCEHELVKKITFTGSTKIGQLLMGQS 263
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ N+K+ ++ELGG +P I+ DADL+ A+ F GQ C+ A+R++V +YD
Sbjct: 264 SKGKNIKKFSMELGGNAPYIVFKDADLDRALDGIIGCKFRQSGQTCICANRIFVHEDLYD 323
Query: 304 KFVKGAVEYA-KAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+F K V+ K ++G+ F + +GP I + ++KV L++ K +GA++L GG R
Sbjct: 324 EFSKRLVDKIDKTFKLGDGFQDGVTHGPLIHDKSIDKVASLVQDAKTKGADVLIGGSRAS 383
Query: 363 TAG-YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
+ G + QPTV +V + M I EEIFGPV ++KF ++EVI RAN+T+ GLA ++
Sbjct: 384 SLGPLFYQPTVLGNVTESMDIFYEEIFGPVAPLIKFKDVDEVIKRANDTDVGLAGYFYSQ 443
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
N++ ++ + G V VN PFGG K+SG+G+E ++ Y E K +I++
Sbjct: 444 NISTIFDAAEKLNVGMVGVNTGEISEPAVPFGGVKNSGLGKEGSKYGIDDYTELKAIIVA 503
>UniRef50_P23105 Cluster: 2-hydroxymuconic semialdehyde
dehydrogenase; n=92; Bacteria|Rep: 2-hydroxymuconic
semialdehyde dehydrogenase - Pseudomonas putida
Length = 486
Score = 289 bits (710), Expect = 8e-77
Identities = 172/490 (35%), Positives = 259/490 (52%), Gaps = 16/490 (3%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
+K K FI E V + G+ FD SP +G VI +V + + W
Sbjct: 1 MKEIKHFISGELVGSASGKLFDNVSPANGQVIGRVHEAGRAEVDAAVRAARAALK--GPW 58
Query: 65 RLADASQRGKLLYKFADLIERDF-EYL-AKLESYDN----GMVYKNCLRILSGIPDSVRY 118
++R ++L++ AD I F E+L A++ + G +++ R +
Sbjct: 59 GKMTVAERAEILHRVADGITARFGEFLEARMPGHRQAEVAGQPHRHSAR-RANFKVFADL 117
Query: 119 LGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVV 178
L ++A++ P + +Y +++P GV G+I PWN+P+L+ KV ALA G VVV
Sbjct: 118 LKNVANEAFEMATPDGAGALNYGVRRPKGVIGVISPWNLPLLLMTWKVGPALACGNCVVV 177
Query: 179 KPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGED-AGVALTHHPDVAKISFTGSLEVG 237
KP+E+TPLT + AG+P GV N+V GFG D AG LT HPDV +FTG G
Sbjct: 178 KPSEETPLTATLLGEVMQAAGVPAGVYNVVHGFGGDSAGAFLTEHPDVDAYTFTGETGTG 237
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
+ I +AA +++V+LELGGK+ I+ D D++ AI F + GQ+C+ R+YV
Sbjct: 238 ETIMRAAA-KGVRQVSLELGGKNAGIVFADCDMDKAIEGTLRSAFANCGQVCLGTERVYV 296
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
+ I+D FV A+A+++G P D GP I KV + +GA ++ G
Sbjct: 297 ERPIFDAFVARLKAGAEALKIGEPNDPEANFGPLISHKPREKVPSYYQQAVDDGATVVTG 356
Query: 358 G---ERIG--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNY 412
G E G ++QPT++ + DD + EEIFGP I FD+ EE I+ AN+ Y
Sbjct: 357 GGVPEMPAHLAGGAWVQPTIWTGLADDSAVVTEEIFGPCCHIRPFDSEEEAIELANSLPY 416
Query: 413 GLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAY 472
GLA+ I+T N+ A + + +EAG VWVN++ + FGG K SGIGRE G+ ++E Y
Sbjct: 417 GLASAIWTENVRRAHRVAGQIEAGIVWVNSWFLRDLRTAFGGSKQSGIGREGGVHSLEFY 476
Query: 473 LEEKTVIISL 482
E K + + L
Sbjct: 477 TELKNICVKL 486
>UniRef50_Q1AYL0 Cluster: Aldehyde dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Aldehyde dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 482
Score = 289 bits (709), Expect = 1e-76
Identities = 178/475 (37%), Positives = 249/475 (52%), Gaps = 11/475 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+I EWV A GE + +P S + A + WR A +
Sbjct: 11 YIGGEWVPADSGEVEEVRNPARPSEVLGTAPRSDRGEMERAVAAAQ--EALPGWRSALPA 68
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
RG++L + AD+I+ E LA+L + + G +S RY GS ++ G
Sbjct: 69 ARGQILLRAADIIDSRSEELARLMALEAGKPLGESRAEVSRAAAIFRYYGSEGWRLYGVE 128
Query: 131 IPTDGDSFSYT-LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
P+ T ++P+GV GLI PWN P+ + K+ AL G TVV+KPA L
Sbjct: 129 APSTRPGVRITSTREPLGVVGLITPWNFPLAIPSWKMAPALICGNTVVIKPAANAVLNAA 188
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ-KAAGTNN 248
+EAG+P GVVN+V G G +G AL V ISFTGS VG IQ +AAG
Sbjct: 189 ELVRILEEAGLPGGVVNLVMGPGGSSGDALVRDERVRAISFTGSTAVGLSIQERAAG--- 245
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
K+V LE+GGK+P ++M DADL A G F + GQ C A+SR V +Y+ F++
Sbjct: 246 -KKVQLEMGGKNPYVVMEDADLEDAAAKVAYGAFGYAGQKCTASSRAVVVEEVYEAFLEQ 304
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER-IGTAGYY 367
VE +A+++G P DE V GP I+ES +LG IE +++G +L GG GYY
Sbjct: 305 VVEATRALKLGEPLDEEAVIGPVINESQYESILGAIEQAREDGRVVLDGGATGPREEGYY 364
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
I P + ADV++ A+EEIFGPV +++K + ++ AN+T YGL AGI T +L A
Sbjct: 365 ISPVIVADVDNGSKTAREEIFGPVLAVIKARDFDHAVEIANDTRYGLTAGIATRSLRYAE 424
Query: 428 QFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGI-GRENGIKAVEAYLEEKTVII 480
+F + + G V VN + Q PFGG K SG+ GRE G+ A+E Y KT +
Sbjct: 425 EFIERSQTGLVNVNLPTAGVEFQVPFGGSKQSGVGGREQGMAAIEFYTGWKTASV 479
>UniRef50_Q0I8D9 Cluster: Aldehyde dehydrogenase family protein;
n=3; Bacteria|Rep: Aldehyde dehydrogenase family protein
- Synechococcus sp. (strain CC9311)
Length = 480
Score = 289 bits (709), Expect = 1e-76
Identities = 169/478 (35%), Positives = 254/478 (53%), Gaps = 14/478 (2%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
K+ ++D EW + E +P I K+A F+
Sbjct: 10 KFQLFYVDGEWEVSSSKERLSVINPATEESIGKIALAGDADVEKVVAAATIAFKSFGH-- 67
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNG--MVYKNCLRILSGIPDSVRYLGSLA 123
+ +R LL + E+ + A S + G + + + +GI +L +L
Sbjct: 68 -SSVEERIDLLQNILKIYEQRVDEFASAISMEMGAPIDFARSAQAQAGID----HLSALI 122
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
D ++ + + +P+GVCGLI PWN PI + KV ALAAGCT+V+KP+E
Sbjct: 123 DDVKEYKFERKLRNGDTIVMEPIGVCGLITPWNWPINQIVLKVAPALAAGCTMVLKPSEL 182
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPL+ EAG+PKGV N++ G G AG AL+ HP+VA ISFTGS G+ I +
Sbjct: 183 TPLSAILFAEVMHEAGVPKGVFNMIHGLGNVAGSALSKHPNVAMISFTGSTGAGRSIIRN 242
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ + + TLELGGKSP ++ D +L+ AI F + GQ C AA+R+ V+ +Y+
Sbjct: 243 S-AERIAKTTLELGGKSPNLVFADCELSTAIDQGIDACFINSGQSCDAATRMLVERSVYE 301
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG---ER 360
K ++ A + + I VG+P GP + + ++V LI G +EGA ++GG +
Sbjct: 302 KSIELAHDKCERISVGDPTKSGNHLGPLVSQIQFDRVQSLIACGLEEGARCISGGLGKPQ 361
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY+ +PTVFADV + M IA+EEIFGPV ++ FD+ +E I+ AN+ YGLAA I T
Sbjct: 362 ECQVGYFARPTVFADVKNTMKIAREEIFGPVLCMIPFDSEKEAIELANDNAYGLAAYIQT 421
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ A ++ + +G+V +NN +A +PFGG+K SG GRE G + V YLE K +
Sbjct: 422 LDQGRAQTVARLLRSGSVNINNSF-IAPGSPFGGYKLSGTGREGGAEGVNEYLEVKVI 478
>UniRef50_Q9RBF6 Cluster: Succinate semialdehyde dehydrogenase;
n=13; Bacteria|Rep: Succinate semialdehyde dehydrogenase
- Ralstonia eutropha (Alcaligenes eutrophus)
Length = 483
Score = 289 bits (708), Expect = 1e-76
Identities = 163/471 (34%), Positives = 240/471 (50%), Gaps = 7/471 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T ID EW A+ G +P G I V WR
Sbjct: 11 THCLIDGEWTGAQSGAELAVCNPATGERIGSVPLAGAAEAEQAVRAAERALPA---WRAQ 67
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+L ++ADL+ E LA+L + + G + ++ + + G A ++
Sbjct: 68 TGKAVPPVLRRWADLMLAHQEDLARLMTAEQGKPLPDARGEVAYAASFLEWFGEEAKRVD 127
Query: 128 GDTIPTDGDSFSY-TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G+ + + S L++PVGVC I PWN P M KV ALAAGCT++VKPAEQTPL
Sbjct: 128 GEVLASPRSSQKMLVLREPVGVCAAITPWNFPAAMITRKVGPALAAGCTIIVKPAEQTPL 187
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ-KAAG 245
T ++AG+P+GV+ +V G G L P V K+SFTGS +GKL+ + AG
Sbjct: 188 TALALAVLGEQAGVPRGVLQVVTGDAVQIGGVLCASPVVRKLSFTGSTAIGKLLMAQCAG 247
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
T +K+++LELGG +PLII +DAD++ A+ + F + Q CV A+R+YV +YD+
Sbjct: 248 T--VKKLSLELGGNAPLIIFDDADMDSAVEGIIASKFRNTRQTCVCANRIYVHDRVYDEV 305
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
+ V + + G+ D GP ID + KV I +GA +L GG+R G
Sbjct: 306 ARRLVSAVEQLLPGHGVDSGVTQGPLIDADAVAKVEAHIADALAQGATVLTGGQRHALGG 365
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
+ PTV A+ M +A+EE FGP+ + +F + EV+ AN+T GLAA F+ ++
Sbjct: 366 TFFAPTVLANATASMRVAREETFGPLAPLFRFTSEAEVVAMANDTESGLAAYFFSRDMAK 425
Query: 426 ALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ ++ +E G V +N L APFGG K SG+GRE ++ YLE K
Sbjct: 426 IWRVAQGLEYGMVGINTGLISNEVAPFGGVKQSGLGREGSRHGIDEYLETK 476
>UniRef50_A3U0D4 Cluster: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenase; n=1; Oceanicola batsensis
HTCC2597|Rep: 5-carboxymethyl-2-hydroxymuconate
semialdehyde dehydrogenase - Oceanicola batsensis
HTCC2597
Length = 502
Score = 289 bits (708), Expect = 1e-76
Identities = 156/425 (36%), Positives = 240/425 (56%), Gaps = 5/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
W + R + L D I + + LA+LE+ + G+ + + + R+
Sbjct: 67 WSRTTVADRQRALMAIHDAILANADELARLETLNTGIPLGQTRTMHIPRAAQNFRFFAEF 126
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
++ G+ + S +P+GVC LI PWN+P+ + K+ ALA G T VVKP+E
Sbjct: 127 INQDNGEVFTQEPGYMSLVTHEPMGVCALIGPWNMPLGLTAMKMAGALAFGNTCVVKPSE 186
Query: 183 QTPLTXXXXXXXXKEAG-IPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
TPLT +G +P+GV+N+V G G G AL+ HPD+ +SFTG E G I
Sbjct: 187 ITPLTLARLFEILAASGALPEGVINLVNGRGHVTGTALSGHPDIDMVSFTGGTETGARIL 246
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
A +K +ELGGKSP I+ +DADL+ AI A G F + GQ+C+A SRL+VQ G+
Sbjct: 247 TALA-RGIKGGAMELGGKSPSIVFDDADLDRAIDGAMLGSFMNNGQMCLAGSRLFVQRGV 305
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
D+F++ + +A+R+G+PFD +T GP I+E+ + +V + +G ++GA L+AGG R
Sbjct: 306 ADRFIEAFTDRTRALRIGDPFDPATEVGPMINEAQLKRVERFVASGLEDGAELIAGGARH 365
Query: 362 GTA--GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
G+YIQPT ++ + I +EEIF P +I FD EEV+ RAN++ +GL ++
Sbjct: 366 EALPDGFYIQPTAMIAQSNALAICQEEIFAPFATIQIFDDEEEVVGRANDSIFGLVGYVW 425
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T +L A + S+ ++ GTV VN + + FGG + SGIGRE + + E K+ I
Sbjct: 426 TRDLERAFRLSRGLQTGTVLVNTPIMRDLRTGFGGIRQSGIGREGAKGSRAMFTEMKSTI 485
Query: 480 ISLPK 484
++L K
Sbjct: 486 VALEK 490
>UniRef50_Q0CFZ9 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 490
Score = 288 bits (707), Expect = 2e-76
Identities = 169/420 (40%), Positives = 232/420 (55%), Gaps = 6/420 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W+ +QR L K++ LI + E L LE+ G C + D Y S+
Sbjct: 72 WQAMTDNQRRDALIKYSKLIRENREQLHWLEAVLVGKDASFCNMEIDVAADLFIYYASMI 131
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DK + + DS YTL+QP G+C I P+N I+ KV ALA G ++++K +E
Sbjct: 132 DKFESAVVAAKDDSLQYTLRQPWGICAGICPFNGVIITLAMKVAPALACGNSIIIKTSEL 191
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
P + +AGIP G N + G G AG AL+ H +V KISFTGS+ VGKLIQ A
Sbjct: 192 NPFSTLFMASLATQAGIPPGAFNCLVG-GAAAGNALSSHMEVRKISFTGSIGVGKLIQVA 250
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A +NLK VTLELGGKSPLI+ DADL A+P A + GQ C +RLYV I D
Sbjct: 251 AAKSNLKSVTLELGGKSPLIVFADADLEKALP-AATLFLLMNGQGCALPTRLYVHESIAD 309
Query: 304 KFV---KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
+FV K VE G+P ST + P VL IE G +E A LL GG+
Sbjct: 310 EFVAKLKSMVEEHGRSLGGDPTLPSTRSSPLYHHRQKEIVLSYIEAGSRE-ATLLTGGKP 368
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
+G G Y +PT+F + + + +EEIFGPV ++ F T +EV+ AN+T +GLAA ++T
Sbjct: 369 VGDKGCYFEPTIFVEPRHNARVLREEIFGPVLVVVLFSTEDEVVALANDTEFGLAAYVWT 428
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+++ AL+ S+ +E GTV VN + P GG+K SG G ENG +A+ + + K+V I
Sbjct: 429 ADISRALRMSQKLEVGTVSVNGAGGIHPSIPMGGWKQSGQGVENGKEAMLEWTQSKSVAI 488
>UniRef50_P38067 Cluster: Succinate-semialdehyde dehydrogenase
[NADP+]; n=106; cellular organisms|Rep:
Succinate-semialdehyde dehydrogenase [NADP+] -
Saccharomyces cerevisiae (Baker's yeast)
Length = 497
Score = 288 bits (707), Expect = 2e-76
Identities = 166/481 (34%), Positives = 247/481 (51%), Gaps = 10/481 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+ID +WV D E F+ P G +IA+V + F+ ++
Sbjct: 22 YIDGKWVKGTD-EVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKT---YKNTTPR 77
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R K L +L+ + + LA + + +NG + + A ++ G T
Sbjct: 78 ERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGAT 137
Query: 131 I-PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
I P + + +T++QPVGVCG+I PWN P M K ALA GCTVV+KP QTPL+
Sbjct: 138 IQPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSAL 197
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDA--GVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
++AG PKG N++ G L P V K++FTGS VGK++ K + ++
Sbjct: 198 AMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQS-SS 256
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
LK+++ ELGG +P I+ DADL+ A+ A + F GQ CV A+RLYV S I DKF K
Sbjct: 257 TLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAK 316
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG-Y 366
E K +G+ D T +G I+ S + KV + +GA ++ G R+ G
Sbjct: 317 LLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPN 376
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ P + + V ++KEE FGP+ I FDT+EEV+ AN+T +GLAA +F+ N+N
Sbjct: 377 FYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTL 436
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII-SLPKK 485
S+ +E G V N + PFGG K+SG GRE + +E Y KT+ I +LP
Sbjct: 437 YTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITIGNLPNS 496
Query: 486 L 486
+
Sbjct: 497 I 497
>UniRef50_Q29491 Cluster: Aldehyde dehydrogenase, cytosolic 2; n=20;
Eumetazoa|Rep: Aldehyde dehydrogenase, cytosolic 2 -
Macroscelides proboscideus (Short-eared elephant shrew)
Length = 240
Score = 288 bits (707), Expect = 2e-76
Identities = 140/238 (58%), Positives = 174/238 (73%)
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
NLKRVTLELGGKSP I+ DADL+ A+ +A G+FFHQGQ CVAASRL+V+ IYD+FV+
Sbjct: 1 NLKRVTLELGGKSPCIVFADADLDNAVEFAHRGLFFHQGQCCVAASRLFVEESIYDEFVR 60
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
+VE AK +GNP GPQID+ +K++ LIE+GKKEGA L GG G GY+
Sbjct: 61 RSVERAKKYVLGNPLTPGVSQGPQIDKEQYDKIIDLIESGKKEGAKLECGGGPWGNKGYF 120
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
IQPTVF++V D+M IAKEEIFGPVQ I+KF +L+EVI RANNT YGLAAG+FT +L+ A+
Sbjct: 121 IQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTFYGLAAGVFTKDLDKAV 180
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
S ++AGTVWVN Y+ + Q PFGGFK SG GRE G + Y E KTV + + KK
Sbjct: 181 TVSAALQAGTVWVNCYMANSVQCPFGGFKMSGNGRELGEYGLHEYTEVKTVTMKISKK 238
>UniRef50_UPI000023D4C2 Cluster: hypothetical protein FG11482.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG11482.1 - Gibberella zeae PH-1
Length = 365
Score = 287 bits (705), Expect = 3e-76
Identities = 147/286 (51%), Positives = 188/286 (65%), Gaps = 4/286 (1%)
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
K AG P GVVNIV G G +AG A+T HP + KI+FTGS GK I K A + LK VTLE
Sbjct: 73 KMAGFPAGVVNIVNGCGAEAGSAITAHPGIDKIAFTGSTITGKTIMKKA-SETLKSVTLE 131
Query: 256 LGGKSPLIIMNDADLNLAIPYAGSGVFF--HQGQICVAASRLYVQSGIYDKFVKGAVEYA 313
GGKSPLI+ +DAD A+ ++ G+ + GQIC A SR++VQ IY+KF++ E
Sbjct: 132 TGGKSPLIVFDDADFEQAVKWSNCGIMGLGNMGQICTATSRIFVQDTIYEKFLEAFHEQV 191
Query: 314 KAIRV-GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTV 372
K+ V G+PFDE+T +GPQ+ ++ K+L LIE+GK EGA LL GG R G G+YIQPTV
Sbjct: 192 KSSTVIGDPFDENTTHGPQVSKAQYEKILSLIESGKSEGAGLLTGGARSGDKGFYIQPTV 251
Query: 373 FADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKH 432
F DV +M I +EEIFGP I F T + I+RAN+T YGL A IFT NL A + +
Sbjct: 252 FRDVKPNMKIVREEIFGPCFVIAPFSTEADAIERANDTEYGLGAAIFTENLRKAHRVAAG 311
Query: 433 VEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
V+AGTVW+++ PFGG+K SGIGRE G A+ AY + K V
Sbjct: 312 VQAGTVWIDSSQDTHWGVPFGGYKKSGIGRELGSYALSAYTQVKAV 357
>UniRef50_Q18822 Cluster: Aldehyde dehydrogenase protein 10; n=2;
Caenorhabditis|Rep: Aldehyde dehydrogenase protein 10 -
Caenorhabditis elegans
Length = 506
Score = 287 bits (705), Expect = 3e-76
Identities = 186/486 (38%), Positives = 255/486 (52%), Gaps = 22/486 (4%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI NE+ A+ + D+ +P G K+ G F+ W+
Sbjct: 31 FIGNEF--ARSEKLMDSVNPSTGKPWIKIPDGTAREVDQAVEAAKEAFKT---WKKTTVQ 85
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD----KI 126
QR LL K A+LIE + +A LES D G L + IP V+ A+ +
Sbjct: 86 QRSALLNKVANLIEEFNDDIAILESRDQGKPIG--LAKVMDIPRCVQNFRDFANAALYSL 143
Query: 127 QGDTI---PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
TI PT G +Y PVGV GLI PWN+P+ + K+ AL AG TVV KP+E
Sbjct: 144 STSTILEQPT-GKFVNYVKNDPVGVAGLISPWNLPLYLLSFKLAPALVAGNTVVCKPSEM 202
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
T +T K G P GVVN+V G G+ AG L H DV ISFTGS +GK IQ+
Sbjct: 203 TSVTAWVLMHAFKLVGFPPGVVNMVIGEGKSAGQRLVDHVDVPLISFTGSTVIGKKIQED 262
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
N K+V+LE+GGK+P I+ ++ + A S F +QG+IC+ SRL+VQ I+
Sbjct: 263 GAKLN-KKVSLEMGGKNPGIVYSNYRKSDIASIARSS-FLNQGEICLCTSRLFVQKPIFA 320
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----E 359
FVK VE AK VG+P + + G + KV IE KKEGA++L GG +
Sbjct: 321 DFVKSYVEEAKKFTVGDPTTQVQI-GAMNSKVHYEKVKSYIELAKKEGADILCGGVTTIQ 379
Query: 360 RIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
GY+I PTV ++D + +EIFGPV I FDT EEVI+RAN+T YGL+A ++
Sbjct: 380 NGCENGYFITPTVIVGLHDASKVMTDEIFGPVVCITPFDTAEEVIERANSTPYGLSATVW 439
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
+++ + L + + AGTVW N +L PFGG K SG GRE ++ Y + KTV
Sbjct: 440 SSDSDELLNTANELRAGTVWCNTWLARDLSMPFGGCKQSGNGREGLHDSLHFYSDAKTVC 499
Query: 480 ISLPKK 485
+++ K
Sbjct: 500 VNIAAK 505
>UniRef50_Q0S0U5 Cluster: Aldehyde dehydrogenase; n=3;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 500
Score = 287 bits (704), Expect = 4e-76
Identities = 174/490 (35%), Positives = 261/490 (53%), Gaps = 14/490 (2%)
Query: 2 VPEIKYTKLFIDNEWVDAKDGETFDTFSPH-DGSVIAKVAKGQXXXXXXXXXXXXXXFQR 60
+PE + +F+D WVDA G+ + +P VI +V F R
Sbjct: 13 IPEARDYPMFVDGAWVDASSGQWSEVTTPILREHVIGRVPSSSTEDVDRAVRAAQKAFPR 72
Query: 61 NSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYL 119
WR + RG++L + AD I+ E LA+L + D G + R ++ + + RY
Sbjct: 73 ---WRSQHFTARGRILSQIADAIDVRAEELARLTALDTGNALRTQARPEVATLANLFRYF 129
Query: 120 GSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
+A +I+G +P D Y+ ++P+GV G ILPWN P+++ K+ AL AG TVVVK
Sbjct: 130 AGVAGEIKGTVLPAGDDQLQYSRQEPLGVIGCILPWNSPLMIAGFKIPAALVAGNTVVVK 189
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
AE PL+ E +P GV+N++ G G AG AL HPDV KISFTGS EVG+
Sbjct: 190 AAEAAPLSVLLLAEICAEF-LPAGVLNVITGSGRVAGEALVQHPDVDKISFTGSTEVGRH 248
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADL--NLAIPYAGSGVFFHQGQICVAASRLYV 297
+ + AG L V+LELGGK+P I+ D D+ + S QGQ C A SRL++
Sbjct: 249 VAREAG-GRLAHVSLELGGKNPSIVFPDVDIDEDFINQLLLSTRVHRQGQSCTAGSRLFL 307
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETG--KKEGANLL 355
IYD+ + V ++VGNP DEST G I+E+ V G ++ G + A +L
Sbjct: 308 HQDIYDEVLDRLVNTLADLKVGNPLDESTDMGAIINETQFASVCGFLDDGLSSTQVATVL 367
Query: 356 AG--GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYG 413
G + + GYY+ PTVF+ ++ +++EEIFGP + ++ +VI AN+++YG
Sbjct: 368 DGSPAKVPNSDGYYMGPTVFSGADNSWRLSREEIFGPALVAIPWNDHSDVIAMANDSHYG 427
Query: 414 LAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKA-VEAY 472
LAA ++T NL+ AL + +E G V VN +GG+K SG+GRE ++ + +
Sbjct: 428 LAAYVWTRNLDLALSTAHALETGWVQVNQGGGQMVGQSYGGYKQSGLGREVSLEGMIAGF 487
Query: 473 LEEKTVIISL 482
+ K V + L
Sbjct: 488 TQTKQVNVRL 497
>UniRef50_Q92VA3 Cluster: Putatively membrane-anchored aldehyde
dehydrogenase protein; n=38; cellular organisms|Rep:
Putatively membrane-anchored aldehyde dehydrogenase
protein - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 794
Score = 286 bits (701), Expect = 1e-75
Identities = 168/467 (35%), Positives = 243/467 (52%), Gaps = 16/467 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ +V + G++FDTF P G ++AK+A G + W
Sbjct: 36 FINGAFVGSASGKSFDTFEPATGKLLAKIAHGGRDDVNAAVAAAR---KAQGPWAKLSGH 92
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R + LY A LI+R +A +E+ DNG + I IP + R+ A Q
Sbjct: 93 ARARHLYALARLIQRHARLIAVVEALDNGKPIRETRDI--DIPLAARHFYHHAGWAQLQE 150
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ + PVGV G ++PWN P LM KV ALA G +V++KPAE TPLT
Sbjct: 151 T-------EFADQVPVGVVGQVIPWNFPFLMLAWKVAPALALGNSVILKPAEFTPLTALL 203
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI-QKAAGTNNL 249
AG+P GV+N+V G GE G + H D+ KI+FTGS EVG+LI +K AG+
Sbjct: 204 FAELAAAAGLPPGVLNVVTGEGE-TGALIVEHEDIDKIAFTGSTEVGRLIREKTAGSG-- 260
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K +TLELGGKSP I+ +DAD++ A+ ++F+QGQ+C A SRL VQ G+ F
Sbjct: 261 KSLTLELGGKSPFIVFDDADIDAAVEGVVDAIWFNQGQVCCAGSRLLVQEGVAPVFHDRL 320
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
+ +RVG+P D++ + + ++ L+ G EGA++ + G + +
Sbjct: 321 KRRMETLRVGHPLDKAIDMAAIVAPVQLQRIEELVAKGVAEGASMHQPKIELPKGGSFFR 380
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PT+ V +A EEIFGPV + F T EE I AN++ YGLAA +++ + AL
Sbjct: 381 PTLLTGVQPTSVVATEEIFGPVAVSMTFRTPEEAIQLANHSRYGLAASVWSETIGLALHV 440
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ + AG VWVN + FGG ++SG GRE G + YL+ K
Sbjct: 441 AAKLAAGVVWVNATNLFDASSGFGGKRESGFGREGGREGCYEYLKPK 487
Score = 87.8 bits (208), Expect = 6e-16
Identities = 70/258 (27%), Positives = 108/258 (41%), Gaps = 9/258 (3%)
Query: 2 VPEIKYT-KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQR 60
VP + T KLF+ + + SP G VI +V +G
Sbjct: 512 VPALDRTAKLFVGGKQARPDGNYSRPVLSPK-GKVIGEVGEGNRKDIRNAVVAARGA--- 567
Query: 61 NSEWRLADASQRGKLLYKFAD-LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYL 119
S W A A R ++LY A+ L R E+ ++ + + + I Y
Sbjct: 568 -SGWSSATAHNRAQILYYIAENLSSRGAEFAGRIAAMTGASAANARAEVEASIARLFSY- 625
Query: 120 GSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
G+ ADK +G + + +P GV G+I P P+L ++ V +A G VV
Sbjct: 626 GAWADKYEGTVHQPPLRGVALAMPEPQGVVGVICPPEAPLLGLVSLVAPLIAVGNRVVAV 685
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
P+E PL + + +P GV+NIV G + AL H DV + GS E+ L
Sbjct: 686 PSEAHPLAATDFYSVLETSDVPPGVINIVTGSAIELAKALAAHNDVDALWAFGSPELSTL 745
Query: 240 IQKAAGTNNLKRVTLELG 257
++K + NLKR ++ G
Sbjct: 746 VEKLS-VGNLKRTFVDYG 762
>UniRef50_A0JWG2 Cluster: Aldehyde dehydrogenase; n=4;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 506
Score = 286 bits (701), Expect = 1e-75
Identities = 167/480 (34%), Positives = 241/480 (50%), Gaps = 15/480 (3%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+F+D W A+ P G V V G F + W
Sbjct: 27 IFVDGAWTPARGTGRNPVTDPATGEVWGSVPDGSPEDVDAAVGSARRAFD-DGMWPRLTP 85
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
S+R L + A+ +E+ E L+ + +NG + RY +LA ++ +
Sbjct: 86 SERAAYLLRIAEEVEKRAEELSLTNTRENGSPVSESAGAAANAAGIFRYFATLAGYLERE 145
Query: 130 TIPT--DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+ G S ++P+GVC LI PWN PI + + K+ AL AGCTVV+KPA TPL+
Sbjct: 146 DVRAFPQGGGESVVRREPIGVCALIAPWNFPINLVVIKLAPALLAGCTVVIKPASPTPLS 205
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
AG+P GVVN+V G G G +L HP V K++FTGS VG+ I A G
Sbjct: 206 LRVIIDAVAAAGVPAGVVNLVTGSGR-LGDSLVKHPGVDKVAFTGSTPVGRKIAAACG-E 263
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
L+ VTLELGGKS I++ DADL+ + GQ C ++R+ + Y++ V
Sbjct: 264 LLRPVTLELGGKSSAIVLPDADLDAMSKVLIRSSMRNTGQTCYISTRILAPASRYEEVVD 323
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG----- 362
A + G+P D TV GP ES VL +E+G EGA GG
Sbjct: 324 MVTSTIAAGKQGDPLDPDTVFGPCATESQYRTVLEYVESGLAEGARATTGGRAASLGGGL 383
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFD----TLEEVIDRANNTNYGLAAGI 418
GY+++PTVFADV +M I++EEIFGPV ILK++ + +E ++ ANNT +GL +
Sbjct: 384 EGGYFVEPTVFADVTPEMRISREEIFGPVICILKYNDAGGSADEAVELANNTEFGLGGLV 443
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
F + AL + ++ G+V + N+ H APFGG DSG+G E G++ + AYL K++
Sbjct: 444 FGADPEAALAVADRMDTGSVGI-NFFASNHAAPFGGRHDSGLGTEYGVEGLNAYLSYKSI 502
>UniRef50_Q4A0Q9 Cluster: Succinate-semialdehyde dehydrogenase; n=2;
Staphylococcus|Rep: Succinate-semialdehyde dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 459
Score = 284 bits (697), Expect = 3e-75
Identities = 156/425 (36%), Positives = 233/425 (54%), Gaps = 5/425 (1%)
Query: 59 QRNSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRY 118
Q W+ DA +R L ++A LI+ + LA+L + + G ++ V++
Sbjct: 35 QAFQNWKKVDAHERSAKLAQWAQLIDDHQDELARLITLEGGKPLAEAKGEVAYANSYVKW 94
Query: 119 LGSLADKIQGDTIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
A ++ G TIP + S + K PVGV G I PWN P M K+ ALAAGCT++
Sbjct: 95 YAEEAKRVYGRTIPANSPSKKIVIDKFPVGVVGAITPWNFPAAMITRKMAPALAAGCTII 154
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
KPA +TPLT +AG PK ++ + G+DAG T+H ++K++FTGS VG
Sbjct: 155 CKPAVKTPLTTIKLVELAHQAGFPKDAISYIIASGKDAGDIFTNHSLISKVTFTGSTAVG 214
Query: 238 K-LIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
K LI+ +A +K VT+ELGG +PLI+ NDAD+ A+ + F + GQ C+ A+R+Y
Sbjct: 215 KSLIESSA--QQVKNVTMELGGLAPLIVHNDADIEAAVDGTIASKFRNAGQTCICANRIY 272
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
V I + + + +E A+ VG+ E GP ID + KVL I+ +++G L
Sbjct: 273 VHEDIAEAYNEKLIEKVHALSVGDGLKEEVKIGPLIDNQAVEKVLTHIKDAQEKGGQLSR 332
Query: 357 GGERI-GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLA 415
E I G +++P V + N DM EE FGPV ++ + L+EVI+ AN+T +GLA
Sbjct: 333 SIEDIQALGGNFLKPVVITNANLDMKAMHEETFGPVAPVMTYSDLDEVINIANDTEFGLA 392
Query: 416 AGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEE 475
+ FT + L+ +E G + N+ A APFGG K+SG GRE G++ +E YLE
Sbjct: 393 SYFFTNDYRTGLKLFNELEYGVIGWNDGGPSAAHAPFGGLKESGYGREGGVEGIEPYLET 452
Query: 476 KTVII 480
K + I
Sbjct: 453 KYLSI 457
>UniRef50_Q1GID6 Cluster: Betaine-aldehyde dehydrogenase; n=5;
Proteobacteria|Rep: Betaine-aldehyde dehydrogenase -
Silicibacter sp. (strain TM1040)
Length = 494
Score = 283 bits (695), Expect = 5e-75
Identities = 157/476 (32%), Positives = 243/476 (51%), Gaps = 9/476 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID V A+ G ++F P + A G F + WR +
Sbjct: 24 FIDGRLVPAETGNRMESFDPGRATAFGDFAAGTAVDVDRAVSSAVAGF---AIWRDTAPA 80
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R +L + A L+ + ++LA +ES D+G + G Y ADK+ G +
Sbjct: 81 TRCAVLMEAARLMRAEADWLAVIESLDSGKTLAEAYGDVQGSARLFEYYAGAADKLDGRS 140
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ D+ ++TL++PVGV I+PWN P + + ALAAGC+ VVKPAE TP T
Sbjct: 141 VNLGNDNAAFTLREPVGVTAHIVPWNYPTSTLVRGIAPALAAGCSAVVKPAETTPYTALM 200
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
AG+P GVVN+V G G +AG L P V ++FTGS++ G + +A N+
Sbjct: 201 IAELLIRAGLPAGVVNVVTGTGPEAGAPLVRDPRVRHVTFTGSVQTGVGVMQAVAP-NVT 259
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
+TLELGGKSPL+ DAD A +F + GQIC A SRL V ++ + ++ V
Sbjct: 260 GLTLELGGKSPLVAFADADAEKVAEGALWAIFSNAGQICSAGSRLVVHRDLHAQVLERLV 319
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT----AGY 366
+ A +R G+ + G E + G +E + G +L GG+ G+
Sbjct: 320 KKATTLRFGHGLHNPDM-GALNSERHQAAISGHVERARARGVEILCGGQATTDPATGKGW 378
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ +PT+ ++ D ++EIFGPV + FD +E + AN T + LAAG++T + + A
Sbjct: 379 FFEPTILDALSADDPAIQQEIFGPVLGVQVFDDEDEALALANGTEFALAAGVYTKDTSTA 438
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ ++ ++AG V VN+Y + PFGG + SG GRE G++ V+AY K + +++
Sbjct: 439 LRMARRIDAGQVTVNDYWAGGIELPFGGNRKSGFGREKGLEGVDAYTRAKAITLAV 494
>UniRef50_A7SDD6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 847
Score = 283 bits (695), Expect = 5e-75
Identities = 165/464 (35%), Positives = 248/464 (53%), Gaps = 17/464 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ +WV + + +++ +P G V+A +G+ FQ W
Sbjct: 64 FINGKWVKPEGRKVYESKNPATGEVLASTTQGETQDIEDAVKAARTAFQ---SWSKLPGH 120
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R + LY A +++ +A LES DNG + IP+ R+L A Q
Sbjct: 121 ARARHLYSIARHVQKHARLIAVLESMDNGKSVRETRDC--DIPNVARHLYHHAGWAQ--L 176
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T+ + +PVGV G I+PWN P+++ KV ALA G TVV+KPA T L+
Sbjct: 177 MDTEMQGW-----KPVGVVGGIVPWNFPLMLLCWKVCPALAMGNTVVLKPATYTRLSALL 231
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI-QKAAGTNNL 249
EAG+P GV N+V G G G L HPDV K++FTGS EVGKL+ Q AG+
Sbjct: 232 FAEICAEAGLPPGVFNVVTGNGA-FGSQLAGHPDVDKVAFTGSTEVGKLLRQLTAGSG-- 288
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K+++LELGGKSP ++ + ADL+ A+ ++F+QGQ+C A SRL VQ + +K
Sbjct: 289 KKLSLELGGKSPFVVFDSADLDSAVEGVVDAIWFNQGQVCSAGSRLLVQETCAQRMIKKI 348
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
E +R+G+P D+S G +D S V ++E + EGA + + + YY
Sbjct: 349 KERMTHLRLGDPLDKSIDMGAIVDPSQQKSVAKMVEEARAEGAEVYQKCASLPSGCYY-P 407
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PT+ +V I EE+FGPV +L F T +E + ANNTN+GL A ++T NL+ A++
Sbjct: 408 PTLITNVQPVSKIVMEEVFGPVLVVLTFRTAKEAVAIANNTNFGLGASVWTENLSLAMEV 467
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
++AG VW+N + A FGG+++SG GR+ G + + Y+
Sbjct: 468 GLSMKAGAVWINGHNLFDAAAGFGGYRESGYGRDGGKEGLYEYV 511
Score = 86.6 bits (205), Expect = 1e-15
Identities = 70/258 (27%), Positives = 109/258 (42%), Gaps = 8/258 (3%)
Query: 2 VPEIKYT-KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQR 60
+P I +T K++I DG G VIA+VA G +
Sbjct: 560 LPSIDHTYKMYIGGAQ-KRPDGNYSRPILNPSGEVIAQVADGNRKDIREAVEAAH---KA 615
Query: 61 NSEWRLADASQRGKLLYKFADLIE-RDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYL 119
S W A R +++Y A+ +E R E A++ G C + + Y
Sbjct: 616 ASGWGKRAAHNRAQIVYYLAENLEMRRAEVAARISDM-TGQSLDECKAEVDASIQRLFYY 674
Query: 120 GSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
G+ ADK G T + + +PVGV G+ P +L F++ + A+ G TVV+
Sbjct: 675 GAYADKFGGTVQETPFYGATIKIHEPVGVIGIACPDECSLLAFVSLLAPAIIRGNTVVIV 734
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
P+E+ P+ + +P GVVNIV G + L H DV + + GS E K
Sbjct: 735 PSEKYPVVAADMYQVFDTSDLPAGVVNIVTGDRDHLTKYLAEHQDVQAMWYFGSAEGSKF 794
Query: 240 IQKAAGTNNLKRVTLELG 257
++ A+ N+KR + G
Sbjct: 795 VEYASAV-NVKRTWVSYG 811
>UniRef50_A5WDF3 Cluster: Aldehyde dehydrogenase; n=13;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Psychrobacter sp. PRwf-1
Length = 492
Score = 283 bits (694), Expect = 7e-75
Identities = 159/481 (33%), Positives = 254/481 (52%), Gaps = 11/481 (2%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
I++ + +I+ EWVD+ G ++ +P G VI +G F N++W
Sbjct: 8 IQHARHWINGEWVDS--GIKKESINPSTGEVIGSYVEGGKTEAEMAIKAAHDTFT-NTDW 64
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
R + R +L + + + LA + + +NG + +S + ++ + S
Sbjct: 65 R-TNRELRFNVLQEMVQAFDARQDELATILATENGKILGEANFEISLVKPNLNFAASTIY 123
Query: 125 KIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G FS LK+PVGV G+ +PWN P+ + + + ALAAGCT V+K QT
Sbjct: 124 TTYGRAAEWSAGKFSVVLKEPVGVAGISVPWNSPVALLIRSLAPALAAGCTTVLKMPGQT 183
Query: 185 PLTXXXXXXXXKEA-GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
LT +PKGV+N+V G E +TH P V ISFTGS G+ +Q+
Sbjct: 184 ALTNATIADILASIKSLPKGVINMVTGERELLETIVTH-PHVPTISFTGSTNTGRALQEE 242
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
G LKR LELGGK+PLI+ NDAD++ IP A + GQ C+ SR+ VQS + +
Sbjct: 243 -GAKQLKRFGLELGGKTPLIVFNDADIDALIPKAEKALTVFAGQFCMTGSRILVQSDVAE 301
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+ + VE ++VGN D + G ID + +N+V G++E +GA +L G +
Sbjct: 302 QVRQKLVERLANVKVGNALDPESDMGALIDMNSVNRVDGMVEDAIAKGAKVLLRGGKFTD 361
Query: 364 A----GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
G + QP + ++ I + E+FGPV ++ FDT E I+ AN T YGLAA I+
Sbjct: 362 GELAKGAFYQPCLLEVDDNQADIVQSEVFGPVLTLQVFDTEAEAIELANGTQYGLAASIW 421
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
T +++ L+ ++ +EAGT+W+N+++ M + GG+K SG GR G+ ++E ++E K ++
Sbjct: 422 TQDVDRPLRIARAIEAGTIWINDWVVMRDEFEEGGYKQSGSGRLRGMASIEDFIEYKHIV 481
Query: 480 I 480
+
Sbjct: 482 M 482
>UniRef50_P25553 Cluster: Aldehyde dehydrogenase A; n=57;
Bacteria|Rep: Aldehyde dehydrogenase A - Escherichia
coli (strain K12)
Length = 479
Score = 283 bits (694), Expect = 7e-75
Identities = 158/473 (33%), Positives = 248/473 (52%), Gaps = 6/473 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
++ID ++V + D +P +VI+++ GQ + EW A
Sbjct: 9 MYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAE---RAQPEWEALPA 65
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+R L K + I ++ L + G + + ++ D + Y+ A + +G+
Sbjct: 66 IERASWLRKISAGIRERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAEWARRYEGE 125
Query: 130 TIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
I +D + L K+ +GV ILPWN P + K+ AL G T+V+KP+E TP
Sbjct: 126 IIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTPNNA 185
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
E G+P+GV N+V G GE G L +P VA +S TGS+ G+ I A N
Sbjct: 186 IAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIM-ATAAKN 244
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+ +V LELGGK+P I+M+DADL LA+ + GQ+C A R+YVQ GIYD+FV
Sbjct: 245 ITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVNR 304
Query: 309 AVEYAKAIRVGNPFDESTVN-GPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
E +A++ GNP + + + GP I+ + + +V + +EGA + GG+ + GYY
Sbjct: 305 LGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEGKGYY 364
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
PT+ DV +M+I EE FGPV ++ FDTLE+ I AN+++YGL + I+T NLN A+
Sbjct: 365 YPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNLNVAM 424
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ K ++ G ++N A Q G++ SGIG +G + YL+ + V +
Sbjct: 425 KAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYL 477
>UniRef50_A5V501 Cluster: Aldehyde dehydrogenase precursor; n=4;
Proteobacteria|Rep: Aldehyde dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 494
Score = 283 bits (693), Expect = 1e-74
Identities = 167/484 (34%), Positives = 254/484 (52%), Gaps = 8/484 (1%)
Query: 1 MVPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQR 60
++ +K + ID W++ D FD +P D S+ A V F
Sbjct: 7 LLDRVKRGRFLIDGTWIEPGDRRRFDIVTPSDESLYASVPCATADDVARAVAAARRAFDE 66
Query: 61 NSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLG 120
LA A +RG +L + AD I+ + A + +++ G V + +++ +R
Sbjct: 67 GPWPGLAPA-ERGAVLDRLADAIDARSDLFATIWTHEVGGVLTHGGHMVAASTAVIRDYA 125
Query: 121 SLADKIQ--GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVV 178
L PT G + + +PVGV G I+PWN PILM +K+ AL AGCT+VV
Sbjct: 126 RLGRDFPFIERQAPTAGGAVGMLVHEPVGVVGAIIPWNGPILMLASKIAPALVAGCTLVV 185
Query: 179 KPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGK 238
K + + PL +E G+P GVVNI+ E++ + L +PDV KISFTGS VG+
Sbjct: 186 KTSPEAPLEAVLLGEIVEELGLPPGVVNILMADREESEL-LVRNPDVDKISFTGSSAVGQ 244
Query: 239 LIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQ 298
+ G + R TLELGGKS ++++D+ L++ + V Q C A SR+ V
Sbjct: 245 HVASICG-GRMARATLELGGKSAAVVLDDSPLDVVVGAIAPQVGMLAMQFCSALSRVIVP 303
Query: 299 SGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG 358
+ +D + G + ++VG+PFD +T GP + +++ I++GK +G L AGG
Sbjct: 304 AHRHDDLLDGLAAALRQVKVGDPFDAATQMGPMAMKRQLDRARSFIDSGKADGFTLAAGG 363
Query: 359 ERIG--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
R GYY++PT+F V +D IA+EEIFGPV +++ EE I AN +++GL +
Sbjct: 364 GRPAGLDRGYYLEPTLFGHVRNDARIAQEEIFGPVIAVIPARDEEEAIRLANQSDFGLNS 423
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+FT + A+ ++ + AGTV N + + A FGGFK SGIGRE G + YLE K
Sbjct: 424 SVFTRDAERAMAVARRLRAGTVGHNAFRSDFGIA-FGGFKKSGIGREGGRPGLMPYLEAK 482
Query: 477 TVII 480
TVI+
Sbjct: 483 TVIM 486
>UniRef50_Q397S7 Cluster: Aldehyde dehydrogenase; n=2;
Proteobacteria|Rep: Aldehyde dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 488
Score = 282 bits (692), Expect = 1e-74
Identities = 160/480 (33%), Positives = 251/480 (52%), Gaps = 6/480 (1%)
Query: 1 MVPEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQR 60
M+ E + +L+I EWV D SP +A V F
Sbjct: 1 MIWEGRNDRLYIGGEWVKPDSTHFVDLVSPLTEETMASVISASKVDADAAVAAARRAFD- 59
Query: 61 NSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLG 120
+ W QR +++ + +L+ +A L + + G + +G P S+ +
Sbjct: 60 HGPWPRMSLHQRMEVMARLRELLIEHESLIAHLVTEEMGCPISISRWMQAGGPISMLGMF 119
Query: 121 -SLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
+A I L++P+GV ++PWN P+ + + K+ AL AG T ++K
Sbjct: 120 LEVAPHYPFSQIRRTVTGNGLVLREPLGVVAAVVPWNAPLQIAVLKLAPALLAGNTAILK 179
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
PA +TPL ++AG+PKGV+N++P + L HP V K+SFTGS G+
Sbjct: 180 PAPETPLDACLLAELAEKAGLPKGVLNVLPA-DREVSEYLCLHPAVDKVSFTGSSAAGQR 238
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
+ G N++KR+TLELGGKSP I+++DAD+ A+ G + GQ+C +RL V
Sbjct: 239 LGALCG-NDIKRITLELGGKSPAIVLDDADIGKAVESLRMGSLRNSGQVCSNKTRLLVSK 297
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
D+ + VE +++ VG+PFD T GP + ++V G I GK+E +L GG
Sbjct: 298 HRKDELIDAFVEMVRSMPVGDPFDPLTQIGPLVSARQRDRVEGYIAKGKQEARLVLGGGR 357
Query: 360 RIG-TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
G T G++++PT+FADV+ D IA+EEIFGPV SIL FDT ++ + ANN+ YGL +
Sbjct: 358 PKGLTRGWFVEPTIFADVDPDAVIAQEEIFGPVISILSFDTDDDAVAIANNSAYGLHGAV 417
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
F+ + A+ ++ V G + +N + + +P GG K SGIGRE GI+ + Y+E K++
Sbjct: 418 FSADTERAVNVARRVRTGAIDING-ASAGYHSPLGGRKKSGIGREAGIEGFDGYVEIKSI 476
>UniRef50_Q0RVI3 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcus
sp. RHA1|Rep: Aldehyde dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 484
Score = 281 bits (690), Expect = 2e-74
Identities = 163/472 (34%), Positives = 239/472 (50%), Gaps = 11/472 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+ ID E VD + + P VIA F W+ +
Sbjct: 22 MLIDGELVDGATSQ--NVIDPATEDVIATAPVADSAQVDQAVHAALKAFHT---WQHSTF 76
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
S+R ++ + AD IE+ E +A++ + +NG K+ + R++ + I+
Sbjct: 77 SERSTIIDRIADAIEKRREEIARIITLENGKPLKSAQDEVDWSLSWARHVAGCS--IEST 134
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
I D S +P+GV I+PWN P + KVV AL G TVVVKPA TPL
Sbjct: 135 IIRDDATSRIKIRHKPIGVVAAIIPWNFPFFQMVYKVVPALFCGNTVVVKPAPTTPLNAM 194
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
+E IPKGVVNIV GE AG LT H DV K+SFTGS G+ + A+ L
Sbjct: 195 VMGEILQEI-IPKGVVNIVGDLGE-AGPHLTSHSDVGKVSFTGSTAAGRKVM-ASSAETL 251
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
KRV LELGG I+M+DAD+ S F + GQ+C+ R++V +YD+F
Sbjct: 252 KRVVLELGGNDAAIVMDDADVEKVAEEIFSWAFVNSGQVCINIKRVFVPRPLYDRFCDAF 311
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
+A+A +G+ T GP + +E KK+G ++AGG GY+++
Sbjct: 312 ASHARAATLGHGLAPETDLGPVQNARQYEAAKAYLELAKKDGT-VIAGGNIPDVPGYFVE 370
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PTV D++D + +EE FGPV+SIL +D LE+ + R N+T YGL ++ ++L+ A
Sbjct: 371 PTVVRDIDDASALVREETFGPVRSILSYDDLEDAVARVNDTPYGLGNSVWGSDLDRAAAV 430
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+ +E GT WVN + ++A PFGG K SGIG E GI+ + + E + +S
Sbjct: 431 ADRLEGGTSWVNTHFSLAPDVPFGGRKQSGIGVEFGIQGIMEFTETHVINVS 482
>UniRef50_Q9RZE6 Cluster: Succinate-semialdehyde dehydrogenase; n=1;
Deinococcus radiodurans|Rep: Succinate-semialdehyde
dehydrogenase - Deinococcus radiodurans
Length = 487
Score = 281 bits (689), Expect = 3e-74
Identities = 166/480 (34%), Positives = 257/480 (53%), Gaps = 14/480 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
++ + D EW +A F+ P +G VI +VA + EWR
Sbjct: 16 SQAYFDGEWRNAP--RNFEVRHPGNGEVIGEVADCTPTDARQAIDAAEVALR---EWRQV 70
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+ +RGK+L ++ DL+ E LA+L + + G + + + A +I
Sbjct: 71 NPYERGKILRRWHDLMFEHKEELAQLMTLEMGKPISETRGEVHYAASFIEWCAEEAGRIA 130
Query: 128 GDTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G+ I T+ +PVG+ + PWN P M K ALAAGC +++KPAE +P+
Sbjct: 131 GERINLRFPHKRGLTISEPVGIVYAVTPWNFPAGMITRKAAPALAAGCVMILKPAELSPM 190
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVA-LTHHPDVAKISFTGSLEVGKLI-QKAA 244
T +AG P ++P A + V K++FTGS EVG+L+ Q+AA
Sbjct: 191 TALYLTELWLKAGGPANTFQVLPTNDASALTQPFMNDSRVRKLTFTGSTEVGRLLYQQAA 250
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
GT +KRV+LELGG +P ++ +DADL A + F + GQ CV +R+YVQ G+ ++
Sbjct: 251 GT--IKRVSLELGGHAPFLVFDDADLERAASEVVASKFRNSGQTCVCTNRVYVQRGVAEE 308
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
F++ E A+++G+PFDE+T GP ++++ ++KV ++ +GA GG+ ++
Sbjct: 309 FIRLLTEKTAALQLGDPFDEATQVGPVVEQAGLDKVQRQVQDALTKGAQATTGGQ--VSS 366
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G + QPTV DV D I +EE FGPV + FDT EE + AN++ YGLAA +T +L
Sbjct: 367 GLFFQPTVLVDVAPDSLILREETFGPVAPVTIFDTEEEGLRLANDSEYGLAAYAYTRDLG 426
Query: 425 NALQFSKHVEAGTVWVNNYL--TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + ++ +E G V +N+ L + A PFGG K+SG+GRE G +E YLE K V + L
Sbjct: 427 RAFRIAEGLEYGIVGINDGLPSSAAPHVPFGGMKNSGVGREGGHWGLEEYLETKFVSLGL 486
>UniRef50_Q82GU8 Cluster: Putative aldehyde dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative aldehyde
dehydrogenase - Streptomyces avermitilis
Length = 499
Score = 281 bits (689), Expect = 3e-74
Identities = 166/481 (34%), Positives = 252/481 (52%), Gaps = 16/481 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI EWV A DG ++ P +V+ + F + W
Sbjct: 22 RLFIGGEWV-APDGGHYEVIDPATEAVVGWAPEASRDQVHAAAAAAREAF---AAWSRTP 77
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A +R +L + A+++ R+ A+L ++G + G+ + + + +
Sbjct: 78 AEERAAVLGRAAEVMRRNLVPYAELAQAESGATTGTARGMQVGVGAARFRRYARVEPAEE 137
Query: 129 DTIPTDGDSFSY---------TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
P ++ + ++QPVGV I +N P K+ ALA G TVVVK
Sbjct: 138 PIAPQINEAGPFGRAAVMGALAVRQPVGVVTCITSYNNPWANPAGKIAPALAMGNTVVVK 197
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
PA Q PL+ + AG+P GVVN+V G G AG A PDV +SFTGS VG+
Sbjct: 198 PAPQDPLSVYRMAEALQAAGVPPGVVNVVSGSGAQAGEAAVDCPDVDMVSFTGSTAVGQR 257
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I + G +KR +ELGGK ++ DADL A+ G+ F+ GQIC A +R+ Q
Sbjct: 258 IAEVCG-RGMKRQLMELGGKGAALVFEDADLASAVSGIGTTFSFYSGQICTAPTRVLAQR 316
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
G+YD+ V YA+ + VG+P TV GP I + ++V +E G+KEGA ++ GGE
Sbjct: 317 GVYDRVVDQLAAYARRLPVGDPRAPGTVVGPVISAAHRDRVESYVELGRKEGARVVTGGE 376
Query: 360 RIGTA-GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
R A G+Y+ PT+ AD DM + +EEIFGPV ++L FD EE I+ AN+++YGL +
Sbjct: 377 RPPCATGFYVAPTLLADCTTDMRVVREEIFGPVVAVLPFDDEEEGIELANSSDYGLIDYV 436
Query: 419 FTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++ ++ A + ++ + AG V VN + +APFGGFK SG+GR+ G A+ AY E + +
Sbjct: 437 WSADVARAFRVARRLRAGGVGVNT-VGRNMEAPFGGFKRSGVGRDVGSYALHAYSELQAI 495
Query: 479 I 479
+
Sbjct: 496 V 496
>UniRef50_A3YHV8 Cluster: Aldehyde dehydrogenase family protein;
n=3; Gammaproteobacteria|Rep: Aldehyde dehydrogenase
family protein - Marinomonas sp. MED121
Length = 479
Score = 280 bits (687), Expect = 5e-74
Identities = 171/477 (35%), Positives = 245/477 (51%), Gaps = 17/477 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+++ID W K + + +P IA+V F + W
Sbjct: 11 QVYIDGNWRRTKSTQLYSLINPATQDSIAQVTMASVKDVEDAVAAAHKAF---ASWSNTS 67
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGM-VYKNCLRILSGIPDSVRYLGSLADKIQ 127
A R + AD ++ ++ L + G + L D++RY LA ++
Sbjct: 68 AQTRANYMNAIADEMQTRYQDLIEAHVLSMGCPAHLVGAYHLDCAIDAMRYYAKLAFNME 127
Query: 128 GDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+T +S T K +GVC LI PWN P+ + K+ ALAAGCT++ KPAEQTPLT
Sbjct: 128 KET---RRESVLLTQKA-IGVCALINPWNYPLHQLVGKLAPALAAGCTLIEKPAEQTPLT 183
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+ G+P GV N++ G G + G L HP V +SFTGS G + K A +
Sbjct: 184 DLIMAEIMHKVGLPAGVFNLIFGHGHEIGPLLAEHPKVNMVSFTGSTRAGIEVAKNA-AS 242
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
++KRV ELGGKS II DAD+ A+ Y V + GQ C A +R+ V Y K ++
Sbjct: 243 SVKRVCQELGGKSAFIITQDADIEAAVRYGVEDVMANTGQTCNALTRMLVPKSQYQKVIE 302
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG----ERIGT 363
A + A VG+P T GP V I+ G +EGA+LL GG ER+
Sbjct: 303 VAKQVALEHTVGDPRLAETNMGPLASAKQHQVVKDYIQLGLEEGASLLTGGAELPERL-D 361
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GYYI+PT+F V +M IA+EEIFGPV IL +D +EE I AN++ YGL++ ++ +
Sbjct: 362 KGYYIKPTIFTQVTPEMRIAQEEIFGPVLCILTYDDIEEAITIANDSQYGLSSAVYAKDA 421
Query: 424 NNALQFSKHVEAGTVWV-NNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
AL +K +EAG ++ +Y +M APFGG K SG GRE G +A+E Y+E + +I
Sbjct: 422 ETALAIAKRLEAGQSYIQGSYFSM--HAPFGGVKQSGNGREWGEEALEEYVETQAII 476
>UniRef50_A1SJV5 Cluster: Betaine-aldehyde dehydrogenase; n=23;
Actinobacteria (class)|Rep: Betaine-aldehyde
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 459
Score = 280 bits (686), Expect = 7e-74
Identities = 160/419 (38%), Positives = 235/419 (56%), Gaps = 6/419 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
WR +R LL +FA +++ + LA+LE + G + N + D + Y
Sbjct: 45 WRALPPGERAGLLRRFAAVVDAHVDELAELEVRNAGHTWGNARWEAGNVRDCLNYYAGAP 104
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+++ G IP G T +P+GV G+I+PWN P+ + ALAAG TVV+KPAE
Sbjct: 105 ERLFGRQIPVPG-GVDVTFHEPLGVVGIIVPWNFPMPIAGWGFAPALAAGNTVVLKPAEL 163
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT EAG+P+ V+++V G G G HP V K+ FTGS EVGK I A
Sbjct: 164 TPLTALRIGELALEAGLPEHVLSVVAGKGSVVGERFVTHPLVRKVCFTGSTEVGKRIM-A 222
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+KRVTLELGGKS I+ DAD++ A A VF + GQ C A SR+ V+ YD
Sbjct: 223 GCAEQVKRVTLELGGKSANIVFADADIDAAAASAPYAVFDNAGQDCCARSRILVERSAYD 282
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+F+ + +RV +P DE++ GP I V G ++ + A + GG
Sbjct: 283 EFLSKLQPAVEGLRVLDPGDEASEMGPLISAQQKAAVTGYLDEVEVAFAGSVPGGPV--A 340
Query: 364 AGYYIQPTVFADVNDDMT-IAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G+++ P+V V+D T I +EE+FGPV +++ FD + + +AN+T YGL+ IFT++
Sbjct: 341 EGFWVPPSVVT-VDDPATRIWREEVFGPVVAVMPFDDDADAVAKANDTEYGLSGSIFTSD 399
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
L L+ ++ VEAG + VN++ ++ + PFGG+K SG+GRE G A A+ EEK V I+
Sbjct: 400 LGRGLRVARAVEAGNLSVNSHSSVRYWTPFGGYKQSGLGRELGPDAPMAFTEEKNVFIA 458
>UniRef50_Q13Q02 Cluster: Aldehyde dehydrogenase; n=3; Bacteria|Rep:
Aldehyde dehydrogenase - Burkholderia xenovorans (strain
LB400)
Length = 500
Score = 279 bits (685), Expect = 9e-74
Identities = 155/467 (33%), Positives = 244/467 (52%), Gaps = 10/467 (2%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
ID A DG TF+T P G +A VA F R S W +
Sbjct: 28 IDGRDEQAADGATFETLDPGTGEHLATVAAMGPADVDRAVDAARRAFAR-SGWATMHPND 86
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA-DKIQGDT 130
R L++ AD +ER + ++E+ D G + + + D++RY LA + +
Sbjct: 87 RAIWLHRLADEVERRKAIIGQIEALDAGKIEQQAQGDVQSFVDTLRYFNELALNTERRSA 146
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+P G ++T +QP G CG I+PWN P+++ + ALAAG TVV+KPAE TPL+
Sbjct: 147 LPVSGYE-AWTTRQPWGACGFIVPWNFPMVLIGWNISPALAAGNTVVIKPAEDTPLSAIY 205
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+E G P GV+N+V G GE AG AL+ HP + ++SFTGS EVG+++ +A G NL
Sbjct: 206 LARLAREIGFPDGVINVVTGLGEIAGAALSRHPGLRRMSFTGSPEVGRMVAEACG-RNLV 264
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
LELGGK +I +D ++ + FH GQ+C A+R V I+++FV +V
Sbjct: 265 PCKLELGGKGAAVIFDDVNIEETADKLARAITFHTGQVCCDATRWLVHESIFERFVDASV 324
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGAN-LLAGG--ERIGTAGYY 367
+ ++G D GP + +VLG +E G+++GA +L GG + G G+Y
Sbjct: 325 AALQRTKIGYQLDPGAEMGPVVSAKQRERVLGYLERGQRDGARAVLKGGAVDVAGHDGFY 384
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
+ P + A +++ A+EEIFGPV + F + ++ AN+T+YGLA +++ + A
Sbjct: 385 VSPALLAGSLENVA-AREEIFGPVAFLAPFRDEAQAVELANDTDYGLANSVWSHDPRRAS 443
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLE 474
+ ++ + AG W+N + P+ G SG+G G+ +VE +
Sbjct: 444 RVAEAMVAGNSWINAHNLFPLGVPYAGVNRSGMG--GGVNSVETLFD 488
>UniRef50_Q1ERI2 Cluster: Dehydrogenase; n=1; Monascus
purpureus|Rep: Dehydrogenase - Monascus anka (Monascus
purpureus)
Length = 501
Score = 279 bits (683), Expect = 2e-73
Identities = 163/467 (34%), Positives = 233/467 (49%), Gaps = 10/467 (2%)
Query: 16 WVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKL 75
W + F +P G I V G F+ WR +R
Sbjct: 20 WSCKDASKRFTVVNPATGEPITVVQAGNLDTVQGAIQASHRAFE---SWRWKTRQERSLY 76
Query: 76 LYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG 135
L + AD +++ LA L +NG K+ + + RY GS+ DK+ + G
Sbjct: 77 LLQAADELQKHSHELAVLLCLENGKPVKDASFDVGFLVQVFRYFGSIVDKLPSEFFD-QG 135
Query: 136 DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX 195
+S + +P GVC ILP+N P + K+ LAAG T+V+KP EQ PLT
Sbjct: 136 SIYSSVIYEPHGVCVGILPFNWPPVHAGGKLAPCLAAGNTMVLKPGEQAPLTLMRIVEIL 195
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
+ P VV VPG G + AL +HP V +S TGS G + A L LE
Sbjct: 196 QSV-FPADVVQAVPGLGPEIPQALINHPLVKMVSLTGSTASGSQAAQTAAVT-LTPTVLE 253
Query: 256 LGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKA 315
LGGK+ ++ DADL L + A G FF++G+ C AASR+ V +Y V K
Sbjct: 254 LGGKNAFVVFEDADLELVVRDAIDGAFFNKGESCTAASRILVHKDLYPTLVSRLTAAVKK 313
Query: 316 IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE--RIG--TAGYYIQPT 371
+R G+ DE+T GP + +VL IE GK+EGA L A G+ G + G+++ PT
Sbjct: 314 LRTGDGLDETTHIGPVVSRERQQEVLSYIEQGKREGATLAAQGDPPTAGRLSGGFFVPPT 373
Query: 372 VFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSK 431
+F DV DMTIA+ EIFGPV ++ F+T EE + N++ YGL AG+++++ A++ ++
Sbjct: 374 LFTDVTADMTIAQREIFGPVVTVGSFETEEEAVKTVNSSQYGLFAGVYSSDFTRAMRVTR 433
Query: 432 HVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++ G V VNNY PFGG KDSG GRE+ I + + K V
Sbjct: 434 KLDVGVVLVNNYFRALLGTPFGGVKDSGYGREHWIGTLREWSRVKNV 480
>UniRef50_A6NZ69 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 494
Score = 278 bits (682), Expect = 2e-73
Identities = 168/487 (34%), Positives = 248/487 (50%), Gaps = 10/487 (2%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P + L+I+ EWV DGE + +P DGSV+A V G +
Sbjct: 13 PYFREHLLYINGEWVPQTDGEVMEDRNPADGSVMAMVHMG---GRQDAEKALAAAYAARG 69
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
+W R ++L + A+ +E E L +L ++G + G +R
Sbjct: 70 KWAATAPDVRERILLRAANEMEARAEGLTQLMIAESGSARYKAWGEVMGSAGILRVAAGE 129
Query: 123 ADKIQGDTI-PTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
++ G+ + P S ++ P+GV I P+N P+++ + K+ ALAAG T ++KP+
Sbjct: 130 CRRLHGEVLQPGGAGQMSMAVRSPLGVVLGITPFNYPMILAIKKLAYALAAGNTFILKPS 189
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
TP T + AG+P GV+N+VPG E G L P V ++FTGS VG+ I
Sbjct: 190 PLTPATGLAIAGVFEAAGLPSGVLNVVPGRSEVIGDMLVDDPRVRMVTFTGSSAVGRSIA 249
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
A +LK+V +ELGGK+PLI++ D D A A G F HQGQ+C+A SR+ V+
Sbjct: 250 VRAA-RDLKKVAMELGGKNPLIVLKDFDPVQAADIAAYGAFCHQGQVCMATSRIIVEGDG 308
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y F V A+ ++VG+P +E T+ GP I + G IE +GA LL GG
Sbjct: 309 YQPFCDALVCRAEGLKVGDPREEDTIIGPLIQPEKWKFIDGQIEDALSKGAKLLTGGRH- 367
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G + PTV ADV +M I EE FGPV S+++ EE + N+ YGL+A + T
Sbjct: 368 --EGPWYWPTVLADVTPEMRIFHEETFGPVTSVMRAKDPEEALALCNDNEYGLSAALLTH 425
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMA-HQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
NL A +EAG V +N+ ++ AP GG K SG GRE G ++E + E K + +
Sbjct: 426 NLELAWSMGLRMEAGMVHINDTTFLSGTTAPSGGVKFSGFGREGGRYSMEDFTELKWLTM 485
Query: 481 SL-PKKL 486
+ PKK+
Sbjct: 486 QVGPKKM 492
>UniRef50_A1UDI2 Cluster: Aldehyde dehydrogenase; n=8;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 477
Score = 277 bits (680), Expect = 4e-73
Identities = 157/425 (36%), Positives = 235/425 (55%), Gaps = 7/425 (1%)
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
+W L QRG L A L+ E LA L++ D G ++ D + +
Sbjct: 54 DWALRTPRQRGTALRALATLMRDHSEELALLDAIDGGFPLPAMRDDVTWAADVLELMADD 113
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
A + G TIP + YTL+QP GV I+P+N P+L +K+ L AG VV+K +
Sbjct: 114 ALDLGGRTIPLSAN-LHYTLQQPYGVVARIVPFNHPVLFAGSKIAAPLMAGNAVVLKAPD 172
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPL+ +E +P+G+ +V G G AG AL HP V +I F GS G+ IQ+
Sbjct: 173 QTPLSAIRLAELAREV-LPEGLFGVVTGHGATAGAALVAHPLVRRIGFIGSPGTGRHIQR 231
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQ--GQICVAASRLYVQSG 300
A + +K VTLELGGK+P+I+M DADL A A G+ F GQ C + SRL +
Sbjct: 232 LAAEHGVKYVTLELGGKNPMIVMPDADLEAAAKSAVVGMNFTTTAGQSCGSTSRLLLHEA 291
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
I D+ + V+ AI+VG+P + T GP ID++ +K L IE+G+ GA++L GG R
Sbjct: 292 IADEVIDLVVDQVAAIKVGDPLVDGTDMGPVIDQAQYSKSLRAIESGRAGGASVLTGGGR 351
Query: 361 ---IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
+G+ G+Y+ PTV A V +A++EIFGPV S+L E ++ AN+ +GL A
Sbjct: 352 AQGVGSKGWYVAPTVLAGVAPQADVARDEIFGPVLSVLTVRDEAEAVEVANSVEFGLTAA 411
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
++T +++ A + + ++AG VW+N PFGG+K SG+G E + + +Y + K
Sbjct: 412 VWTNDVSQAHRMAAGLDAGYVWINGSARHYWGLPFGGWKSSGVGSEESTEELLSYTQVKA 471
Query: 478 VIISL 482
V ++L
Sbjct: 472 VTVTL 476
>UniRef50_Q6NTJ6 Cluster: LOC414586 protein; n=11; cellular
organisms|Rep: LOC414586 protein - Xenopus laevis
(African clawed frog)
Length = 830
Score = 277 bits (679), Expect = 5e-73
Identities = 160/464 (34%), Positives = 242/464 (52%), Gaps = 16/464 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +W+ +T+ T +P G +A +G+ F+ W
Sbjct: 46 FIDGKWLKPDGRKTYTTKNPATGEALATTVQGEEEDVETAVKAARKAFE---SWSKLPCH 102
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R + LY A +++ L+ +ES DNG + +P VR+ A Q
Sbjct: 103 VRARYLYSIARTVQKHQRLLSVIESMDNGKPIRESRDC--DVPLVVRHFYHHAGWAQLRD 160
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+G +P+GV I+PWN P+++ K+ ALA G TVV+KPA T LT
Sbjct: 161 TEMNG-------WKPLGVIAAIVPWNFPLMLLTWKICPALAMGNTVVLKPATYTRLTALL 213
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA-AGTNNL 249
EAG+P GV N+V G G G L HPDV K++FTGS EVG+ ++KA AGT
Sbjct: 214 LAEICAEAGLPPGVFNVVTGNGAFGG-KLADHPDVDKVAFTGSTEVGRTLRKATAGTG-- 270
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K+++LELGGKSP I+ + +DL+ A+ ++F+QGQ+C A SRL +Q I + ++
Sbjct: 271 KKLSLELGGKSPFIVFDTSDLDSAVEGIVDAIWFNQGQVCSAGSRLLMQESISEDLIRRL 330
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQ 369
+ +R+G+ D++ G +DE+ + +E + EGA++ I G +
Sbjct: 331 KQRMSHLRLGDSLDKTIDMGALVDETQKKTIEEFVEEARAEGADVFQSPGPIPKKGLFYP 390
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PT+ VN +EEIFGPV + F T +E I N+T YGLAA ++T NL AL+
Sbjct: 391 PTLITGVNTTSRCVREEIFGPVLVAMTFRTAKEAIALGNSTPYGLAASVWTENLPLALEV 450
Query: 430 SKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
+ ++AGTVWVN + A FGG+K+SG GR+ G + + Y+
Sbjct: 451 ALSIKAGTVWVNGHNMFDAAAGFGGYKESGFGRDGGKEGLYEYV 494
Score = 73.3 bits (172), Expect = 1e-11
Identities = 49/194 (25%), Positives = 88/194 (45%), Gaps = 1/194 (0%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W A R +++Y A+ +E + +A+ S G + L+ + + Y G+
Sbjct: 602 WGKRAAHNRAQIVYYMAENLELRRDEVAQRLSTLTGQSKEKALQEVDLSVQRLFYWGAYC 661
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DK G T + +++PVGV G+ P P+L F++ A+ G V++ P+E+
Sbjct: 662 DKYGGTVQETLLYGATVMIREPVGVVGIACPDEYPLLSFVSLFAPAIVRGNAVIMIPSEK 721
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
PL + +P GVVN++ G + L H DV + + GS + K ++ +
Sbjct: 722 FPLPALDFYQVFDTSDLPGGVVNLLTGGRDHLAKYLVEHQDVQAMWYFGSEQGSKFVEWS 781
Query: 244 AGTNNLKRVTLELG 257
+ N KR + G
Sbjct: 782 S-AENCKRTWVNYG 794
>UniRef50_Q8YBN0 Cluster: SUCCINATE-SEMIALDEHYDE DEHYDROGENASE; n=5;
Alphaproteobacteria|Rep: SUCCINATE-SEMIALDEHYDE
DEHYDROGENASE - Brucella melitensis
Length = 483
Score = 277 bits (679), Expect = 5e-73
Identities = 139/418 (33%), Positives = 226/418 (54%), Gaps = 2/418 (0%)
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGS 121
+EW A +R K++ + AD++ + A++ S + G G D + +
Sbjct: 62 AEWSALSALERSKIMRRAADIMRERADAAARIMSMEQGKPLSEARGEWLGSADLLDWFAE 121
Query: 122 LADKIQGDTIPTDGDSFSY-TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
++ G +P+ + LK P+G PWN P + KV AL AGC+VV+KP
Sbjct: 122 EGRRVYGRIVPSRAPNIQIQVLKHPIGPVAAFTPWNFPAWNTMQKVAPALGAGCSVVIKP 181
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
A TP T EAG+P V+++ G + AL P++ K+S TGS VG+++
Sbjct: 182 ASDTPGTAWLIGKCLLEAGLPPKAVSVIWGTTSELSDALIKAPEIRKVSLTGSTRVGRIV 241
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
AG LK+VT+ELGG P+I+ DADL+ IP A F + GQ+CV+ +R V++
Sbjct: 242 AAQAG-EYLKKVTMELGGHGPVIVAADADLDHLIPLAVQWKFRNCGQVCVSPTRFIVEAS 300
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
I+D+F++ E A+ ++VG +E GP ++ + VL ++E +GA + GG R
Sbjct: 301 IHDEFIRRFSEKARELKVGKGVEEGAQMGPLTSQNQLETVLSMVEDALTKGAKIETGGNR 360
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
IG G + +PT+ + + +M EE FGP+ +++ +L+E I +N GL A +FT
Sbjct: 361 IGDTGNFYEPTILSGMTAEMLAMNEEPFGPLALVMRVHSLDEAIAESNRLPVGLGAYLFT 420
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+++ A + H++AG + VN++ + PFGG +DSG G E G++ +EAYL TV
Sbjct: 421 SSMTTAHRVQNHLQAGMLGVNHFALALPETPFGGVRDSGFGSEGGLEGIEAYLTTMTV 478
>UniRef50_Q4Q1P8 Cluster: Aldehyde dehydrogenase, putative; n=5;
Trypanosomatidae|Rep: Aldehyde dehydrogenase, putative -
Leishmania major
Length = 509
Score = 277 bits (679), Expect = 5e-73
Identities = 158/485 (32%), Positives = 251/485 (51%), Gaps = 13/485 (2%)
Query: 3 PEIKYTKLFIDNEWV-DAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRN 61
P +K +I+ WV A +T P +I + F+R
Sbjct: 30 PMMKEPACYINGAWVASALSDKTVTVEDPCTNQIIGAIPCMGYAETTAAIEAARAVFER- 88
Query: 62 SEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVY---KNCLRILSGIPDSVRY 118
W+ QR + ++ +L+ + + +A + S ++G V K + G D Y
Sbjct: 89 --WKEVMPRQRAGAVRRWGELMRKHCDVVANILSRESGKVVAEGKGEVLYAQGYADW--Y 144
Query: 119 LGSLADKIQGDTIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
G A++I GD IP T+ ++PVGV G+I PWN P M + A+AAGCTVV
Sbjct: 145 AGE-AERIYGDIIPGPRPGVQTTVFREPVGVVGIITPWNFPAAMIMRAACGAIAAGCTVV 203
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
+KPAE TP T EAGIP GV N+V G G AL DV K+SFTGS VG
Sbjct: 204 LKPAELTPFTAMALAQLADEAGIPPGVFNVVAGDAPKIGDALVESFDVRKVSFTGSTRVG 263
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
+ + + + +K+VT+ELGG +P I+ DADL A + F + GQ C+ +R V
Sbjct: 264 QHLYRRC-SETMKKVTMELGGNAPCIVFEDADLPRAADQLIAAKFRNAGQTCICVNRALV 322
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
Q+ +YD+F + +A++VG+ FD + G I + + ++ ++E ++GA L+ G
Sbjct: 323 QASVYDEFKSLVADRVRALKVGSSFDPAVKVGAVIGSATLERMTRMVEDAVEKGATLMVG 382
Query: 358 GERIGTAGYYIQPTVFADVNDDMTI-AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
G+ + GY+ +PT+ +V D T+ + E+FGPV ++ FDT + + AN+T GLA+
Sbjct: 383 GKAVEGGGYFFEPTLLTNVPHDTTLCCRNELFGPVLPLVPFDTEDVAVKMANDTQAGLAS 442
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
FT + + ++ + G V VN+ + APFGG K+SG+GR+ +E++++ K
Sbjct: 443 YFFTNDYRRQHRVARALRYGMVGVNDSALSSPAAPFGGVKESGLGRDGSKYGIESFVDIK 502
Query: 477 TVIIS 481
V+ S
Sbjct: 503 YVLFS 507
>UniRef50_Q7WPN3 Cluster: Aldehyde dehydrogenase; n=1; Bordetella
bronchiseptica|Rep: Aldehyde dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 494
Score = 277 bits (678), Expect = 6e-73
Identities = 145/418 (34%), Positives = 223/418 (53%), Gaps = 1/418 (0%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W + A R +L + I + LA+LE+ ++C + + D +Y
Sbjct: 77 WAVMPADGRAAVLLAVSAAIRANLARLAELEAVTAARPIRDCRAQVDRVADMFQYYAGWC 136
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
DK GD IP +YT+++P+GV I+PWN P+ M + +LA G V++KP+E
Sbjct: 137 DKFYGDVIPVPNQYLNYTMREPIGVLLHIVPWNSPLFMAAWHLAPSLATGNAVLLKPSEL 196
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPL+ + AG+P G+V ++ G G G A HP V KI F GS E G + A
Sbjct: 197 TPLSAIALVRIAESAGLPTGLVAVLAGLGHTMGNAAIEHPLVRKIGFVGSPETGAKVAGA 256
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A +K LELGGKS I+ DADL+ +F GQ CVA SRL V +
Sbjct: 257 AA-RVVKPCVLELGGKSANIVFPDADLDQLCEATVKSMFIGAGQTCVAPSRLIVHRSLEQ 315
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+ V+ ++ A + +G P +ST GP + + V +IE G+++GA G +
Sbjct: 316 QVVERLLDAASTLEMGLPELDSTAIGPIHNRRQFDHVNRMIEQGRRDGARCRQAGNAVPQ 375
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G Y+ PT+F V D +A++E+FGPV + L FDT +E ID AN+T +GLA ++T ++
Sbjct: 376 RGLYVPPTIFTGVARDGALARQEVFGPVMACLPFDTEQEAIDLANDTEFGLAGAVWTHDV 435
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
A + + + AGTVW+N Y + ++PFGG SG GR +G +A++ Y K++ ++
Sbjct: 436 KRAHRVAAAINAGTVWINTYKSTDIRSPFGGIGLSGYGRSSGHEALQEYTRLKSIWVA 493
>UniRef50_Q0RV62 Cluster: Aldehyde dehydrogenase; n=1; Rhodococcus
sp. RHA1|Rep: Aldehyde dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 483
Score = 277 bits (678), Expect = 6e-73
Identities = 164/480 (34%), Positives = 246/480 (51%), Gaps = 12/480 (2%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
Y +L++ W DA D T + +P G V+ ++A + W
Sbjct: 8 YDRLYLAGRWSDA-DQPTVEVRNPATGEVVTRIAVA-TLENADAAVAAATQLHEDRTWAD 65
Query: 67 ADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKI 126
+R L AD IER E L ++ + D G + ++ R LA +
Sbjct: 66 LSFGERADRLDAIADAIERRTEELTRIYAEDQGGLVSLAPFVIGQSVGVFRGTAKLARGM 125
Query: 127 QGDTIPTDGDSFSYTLKQ-PVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
G + + PVG +PWN P+++ KV TALAAGC V+VK QTP
Sbjct: 126 DNSPSRRSGSGSDVLIHRVPVGPVLASVPWNGPLILAAVKVATALAAGCPVIVKVDVQTP 185
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
L E G+P G+++++P D L HP V +SFTGS VGK + +AA
Sbjct: 186 LASFLLAEAIDEVGLPPGLISVLPA-EVDVAKHLVSHPGVKHVSFTGSTAVGKDVMRAAA 244
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
N+ R+TLELGGKS I+++D D A P G GQ+C SRL V + ++++
Sbjct: 245 -ENMTRLTLELGGKSAAIVLDDFDPASA-PMLVPGCLAQTGQVCTTFSRLLVPAERFEEW 302
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--T 363
V ++++G+P D +TV GP + + K + ++EG ++AGG+R
Sbjct: 303 KAALVHVFSSLKIGDPTDPATVVGPLVSAQQLEKTEYYVSLAREEGT-IIAGGQRPDGFD 361
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GY+ +PT+ DV D IA+EE+FGPV +L F L++ I AN++ YGLAAGIFT ++
Sbjct: 362 GGYWYEPTLVTDVEPDSRIAREEVFGPVTVLLPFQDLDDAIRIANDSEYGLAAGIFTNDV 421
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+ A++ + H+ AG V +NN+ PFGGF SGIGRE GI+ +E++LE T+ I P
Sbjct: 422 DQAVKIAPHLTAGAVSINNF-GANFLEPFGGFGASGIGREGGIEGIESFLE--TMQIQFP 478
>UniRef50_Q4L803 Cluster: Putative aldehyde dehydrogenase SH0913;
n=18; Bacillales|Rep: Putative aldehyde dehydrogenase
SH0913 - Staphylococcus haemolyticus (strain JCSC1435)
Length = 475
Score = 277 bits (678), Expect = 6e-73
Identities = 169/486 (34%), Positives = 258/486 (53%), Gaps = 33/486 (6%)
Query: 7 YTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRL 66
YT+ +I+ EW+D+ ET + +P VI KVAKG + E+R
Sbjct: 4 YTQQYINGEWIDSDSNETIEVINPATEEVIGKVAKGNSNDVEKAVEAANNVYL---EFRH 60
Query: 67 ADASQRGKLLYKFA--------DLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRY 118
+ +R +LL K D+IE + L + + Y+ L + ++ R
Sbjct: 61 SSVKERKELLDKIVEEYKNRKQDIIEAITDELGAPLTLSENVHYQMGL---NHFEEASRA 117
Query: 119 LGSLA-DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
L S ++ +GD + T K+ +GV GL+ PWN P K+ A AAG VV
Sbjct: 118 LDSFEFEERRGDALVT---------KEAIGVSGLVTPWNFPTNQTSLKLAAAFAAGSPVV 168
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
+KP+E+TP + G+PKGV N+V G GE G L+ HP V +SFTGS G
Sbjct: 169 LKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGEGVGNPLSEHPKVRMMSFTGSGRTG 228
Query: 238 -KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
K+++KA + + K+V+LELGGKSP I+++D D+ A V + GQ+C A +R+
Sbjct: 229 SKIMEKA--SKDFKKVSLELGGKSPYIVLDDVDVKEAAKATTGKVVNNTGQVCTAGTRIL 286
Query: 297 VQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLA 356
+ + F+ E ++VG+P +E T GP I + + V I+ G +EGA L
Sbjct: 287 IPESKKEDFLTALKEEFSKVKVGDPREEGTQVGPIISKKQFDTVQSYIDKGIEEGAELFY 346
Query: 357 GG----ERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNY 412
GG E + T GY+ +PT+F +V++DMTIA+EEIFGPV S++ ++ L+E I AN+T Y
Sbjct: 347 GGPGKPEGLNT-GYFARPTIFINVDNDMTIAQEEIFGPVASVITYNNLDEAIKIANDTKY 405
Query: 413 GLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAY 472
GLA + + + ++ +EAG + +N PFGG+K SGIGRE G +E +
Sbjct: 406 GLAGYVIGKDKETLQKVARSIEAGRIEINEAGNQP-DLPFGGYKQSGIGREWGDYGIEEF 464
Query: 473 LEEKTV 478
LE K++
Sbjct: 465 LEVKSI 470
>UniRef50_Q1V2Q9 Cluster: Probable aldehyde dehydrogenase; n=2;
Candidatus Pelagibacter ubique|Rep: Probable aldehyde
dehydrogenase - Candidatus Pelagibacter ubique HTCC1002
Length = 506
Score = 276 bits (676), Expect = 1e-72
Identities = 161/485 (33%), Positives = 254/485 (52%), Gaps = 14/485 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K+ I+ + AK +P G I + + FQ+ W+
Sbjct: 22 KILINGKLSPAKAEAKISVLNPSTGENIGEAPQCNKVDVNIAVDAAEAAFQK---WKKVP 78
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKN-CLRILSGIPDSVRYLGSLADKIQ 127
A +RGK++ A +E + L + D G + + + + LA +I+
Sbjct: 79 ARERGKIMTAAARKLEDRKNEIETLLALDTGNALRTQAIPETAASIELTHMFAGLAGEIK 138
Query: 128 GDTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G+ P + ++ YT K P+GV I+PWN P+ + + K+ A+ AG TVV+K AEQ PL
Sbjct: 139 GENYPPNIPNTIHYTTKDPIGVVCAIIPWNAPLFLTVAKIAPAIVAGNTVVLKTAEQAPL 198
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
++ +P GV+N++ G+GE+ G L HP V K++FTGS VGK+I A
Sbjct: 199 CALLLCEILQQE-LPPGVLNVISGYGEECGEPLIDHPKVRKVTFTGSFSVGKIIAIKAAP 257
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGV-FFHQGQICVAASRLYVQSGIYDKF 305
L VTLELGGK+P IIM+DADL++AIP G+ + QGQ C A SR+Y+ IYDK
Sbjct: 258 K-LCPVTLELGGKNPNIIMSDADLDIAIPGVIDGMRYTRQGQACTAGSRVYIHEKIYDKV 316
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKK-EGANLLAGGERIGTA 364
++G V +++GN D + G I + + L ++ KK A +L GG +
Sbjct: 317 LEGVVSKLSKLKMGNALDSKSDIGAIISNEQLKRTLHYMDIAKKTSSAKVLHGGNQPKGG 376
Query: 365 ----GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G++ +PT+ + V + + +EE+FGPV + F + +EV+ AN+T +GL+A ++T
Sbjct: 377 DYKEGFFYEPTLLSGVPVESPVCQEEVFGPVACAIPFKSFDEVMKSANDTPFGLSAVLWT 436
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKA-VEAYLEEKTVI 479
NL+ ALQF +EAG V VN + +GG K SG+G+E + + + + KTV+
Sbjct: 437 QNLSRALQFVDEIEAGFVQVNQCVAPRANVSYGGIKMSGLGKEYAFDSMINHFTQSKTVL 496
Query: 480 ISLPK 484
I+ K
Sbjct: 497 INRGK 501
>UniRef50_A0JU81 Cluster: Succinate-semialdehyde dehydrogenase
(NAD(P)(+)); n=32; Bacteria|Rep: Succinate-semialdehyde
dehydrogenase (NAD(P)(+)) - Arthrobacter sp. (strain
FB24)
Length = 514
Score = 276 bits (676), Expect = 1e-72
Identities = 163/479 (34%), Positives = 240/479 (50%), Gaps = 8/479 (1%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T L I+ EW A G+TFD P G V+ +A W
Sbjct: 38 TGLLINGEWRPAASGKTFDVEDPATGKVLLSIADAGPEDGAAALDAAAAA---QDSWAKV 94
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +RG++L + +++ E A L + + G ++ + +R+ A +
Sbjct: 95 PARERGEILRRAFEMVTARAEDFALLMTLEMGKPLAEARGEVTYGAEFLRWFSEEAVRAF 154
Query: 128 GD-TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G ++ DG S K+PVG C LI PWN P+ M K+ A+AAGCT+V+K A TPL
Sbjct: 155 GRYSVSPDGKSRLLVTKKPVGPCLLITPWNFPLAMATRKIAPAVAAGCTMVLKSANLTPL 214
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVA-LTHHPDVAKISFTGSLEVGKLIQKAAG 245
T +EAG+P GV+N++P A L + K+SFTGS EVG+ + A
Sbjct: 215 TSQLFAAVMQEAGLPAGVLNVIPTSTAGATTGPLIKDSRLRKLSFTGSTEVGRRLLSDAS 274
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
L R ++ELGG +P ++ DAD++ A+ A + G+ C AA+R V + D+F
Sbjct: 275 ETVL-RTSMELGGNAPFVVFEDADVDAAVAGAMLAKLRNMGEACTAANRFIVHESVADEF 333
Query: 306 V-KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
K A + A ES V GP ID +KV L+ GA +AGG +
Sbjct: 334 AEKFAAKMADMTTARGTEPESKV-GPLIDAKSRDKVHELVTDAVASGAVAVAGGGPVDGP 392
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GY+ QPT+ V + I EEIFGPV I+ FD+ +E + ANNT YGL A +FT +LN
Sbjct: 393 GYFYQPTILKGVTEGTRILSEEIFGPVAPIITFDSEDEAVRLANNTEYGLVAYVFTRDLN 452
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
++ + +E G + +N + APFGG K SG+GRE G++ +E YL + + I+ P
Sbjct: 453 RGIRMGERLETGMLGLNAGVVSNAAAPFGGVKQSGLGREGGLEGIEEYLYTQYIGIADP 511
>UniRef50_UPI00015BD0F0 Cluster: UPI00015BD0F0 related cluster; n=1;
unknown|Rep: UPI00015BD0F0 UniRef100 entry - unknown
Length = 477
Score = 275 bits (675), Expect = 1e-72
Identities = 160/471 (33%), Positives = 251/471 (53%), Gaps = 15/471 (3%)
Query: 20 KDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKF 79
K G D P+D + I K ++ S A ++ ++LYK
Sbjct: 14 KTGTVLDVIYPYDNTKIGKSYVVNDSYVEKAIEKAKIGLKKLSS---LSAFEKYEILYKT 70
Query: 80 ADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG---- 135
++L+ ++ E +A+ Y+ G K + ++ R+ A +I G T P D
Sbjct: 71 SELLRKNKEEIARTIVYEVGKTIKEARVEVDRAIETFRFSAEEAKRIYGKTYPVDAHPNG 130
Query: 136 -DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXX 194
F + ++ P G+ I P+N P+ + +KV A+AAGC V+VKP+E+TPL+
Sbjct: 131 KSKFGFYIRVPAGIVVAISPFNFPLNLTAHKVGPAIAAGCPVIVKPSEKTPLSPIIMGEL 190
Query: 195 XKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTL 254
EAG+PK ++++PG+G G ALT H DV +SFTGS VG+LI K AG +K++ L
Sbjct: 191 LLEAGLPKEAISVLPGYG-GLGKALTTHKDVRVVSFTGSKMVGELIAKQAG---IKKLVL 246
Query: 255 ELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAK 314
ELG S L+I DADL A A G F GQ+C++ R++V + + F++ E
Sbjct: 247 ELGSNSALVIHKDADLEKAATKAVQGGFSMAGQVCISIQRIFVHEYVLEPFLRLLEEKIS 306
Query: 315 AIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT--AGYYIQPTV 372
I++G+P DE GP ID++ + +V I+ ++GA ++ + I Y+ PT+
Sbjct: 307 NIKIGDPMDEEVDMGPMIDKNQVERVKQWIKEAMEKGAKVVQKAKNIENIKGTNYLLPTL 366
Query: 373 FADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKH 432
DV+ D TI KEE F PV +I ++ ++EV++ N +YGL G++T ++N A++F +
Sbjct: 367 LLDVDKDSTIFKEEAFAPVVNINRYKDIDEVVNIINEGDYGLQIGVYTKDINMAMEFVRK 426
Query: 433 VEAGTVWVNNYLTM-AHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
E G V +N P+GGFK SGIGRE A+E Y E K V+IS+
Sbjct: 427 CEVGGVNINEGPNFRVDHMPYGGFKFSGIGREGPSFAIEDYTEIKNVLISI 477
>UniRef50_Q8PP06 Cluster: Aldehyde dehydrogenase; n=6;
Xanthomonas|Rep: Aldehyde dehydrogenase - Xanthomonas
axonopodis pv. citri
Length = 489
Score = 275 bits (675), Expect = 1e-72
Identities = 162/477 (33%), Positives = 242/477 (50%), Gaps = 11/477 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFID +W + T D +PH + + + F N W
Sbjct: 19 LFIDGQWRASTGDRTVDVIAPHTEERLLRYTEPSPSDTEAAIAAARSAFD-NGPWPQLSP 77
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADK---I 126
+R +L + AD + LA+ + G R PD Y L +
Sbjct: 78 QERSVVLKRVADHLRARMPELAEAWTGQVGATLGFSKRASQQAPDLFDYYADLIATHAFV 137
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
Q P+ G + +++PVGV I PWN P+++ KV ALAAGCTVV KP+ +TP+
Sbjct: 138 QPRVRPSGGRV--HVVQEPVGVVAAITPWNAPLVLLCYKVAAALAAGCTVVAKPSPETPI 195
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
AG+P GV N++P G + G L HP V KISFTGS + G+ I A
Sbjct: 196 DAYILAECISAAGVPDGVFNLLPA-GREVGEQLIRHPHVDKISFTGSTQAGRSIGIAC-A 253
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
L RV LELGGKS I++ DADL +P GQ+C + +R+ V + ++ +
Sbjct: 254 ERLARVGLELGGKSAAIVLEDADLAKMLPTLVPYSMPIAGQVCFSLTRVLVPTQRREEIL 313
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--TA 364
+ A+++G+PF T GP + +V I GK EGA L+ GG R +
Sbjct: 314 QAYCTALSAVKLGDPFAADTGMGPLALGRQLERVQSYIAKGKAEGARLVMGGSRPAHLSR 373
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
G++++PTVFA+V DM IA+EEIFGPV S + + ++I +AN ++YGL I++ +
Sbjct: 374 GFFVEPTVFAEVMPDMAIAREEIFGPVVSFIDYHDEADLIAKANASDYGLHGTIYSEDAE 433
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
A + ++ V +G+ +N + + PFGGFK SGIGRE GI+ + A+LE +T+ +S
Sbjct: 434 RAYRIARRVRSGSHAING-MWVDISMPFGGFKHSGIGREGGIEGLHAFLETRTLYLS 489
>UniRef50_Q7CHE3 Cluster: Succinate-semialdehyde dehydrogenase; n=9;
Yersinia|Rep: Succinate-semialdehyde dehydrogenase -
Yersinia pestis
Length = 498
Score = 275 bits (675), Expect = 1e-72
Identities = 164/475 (34%), Positives = 239/475 (50%), Gaps = 12/475 (2%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFI+ E+ G +P G VI +A F W
Sbjct: 22 LFINGEFRKGAGGR-LPVENPATGKVIGHLAAATPEEIEEAVAAARRAFPA---WAAERP 77
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
R L++ DLI D +A+ + + G + + + + G A ++QGD
Sbjct: 78 KARANALHRLGDLIAGDALNMARNMTIEQGKPVNEAQGEILKLAEICHFYGEEATRVQGD 137
Query: 130 TIPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
+P D F S +++PVGV G I PWN P + K+ +LAAGCT+++KPAE TP T
Sbjct: 138 VVPNDPPGFQSLVVREPVGVVGAITPWNYPAELVGWKLCASLAAGCTLIIKPAELTPYTA 197
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
EAGIP GVVN++ G GE G AL HP V KI+FTGS VG IQ++
Sbjct: 198 LAIAEKCLEAGIPAGVVNVLTGKGEQVGQALVEHPQVDKIAFTGSSAVGLHIQQSC--PQ 255
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+KR++LELGG P+++ AD+ A+ A F + GQ+C+A +R+YV Y FV
Sbjct: 256 VKRLSLELGGNGPMVVTACADVAAAVKGAVRRSFRNCGQVCIAINRIYVHRSCYRAFVSK 315
Query: 309 AVEYAKAIRVGNPFDESTVN-GPQIDESMMNKVLGLIETGKKEGANLLAGG---ERIGTA 364
+R+GN D+ + G +NK +E +GA L+AGG E + A
Sbjct: 316 MGVATNGLRLGNGLDDPAADLGAMASVEPLNKTRAHLEDALAKGARLVAGGKAPEGVEYA 375
Query: 365 -GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G++ +PTV AD M + EE FGP+ + FD ++EVI RAN+T YGLAA ++ +L
Sbjct: 376 KGHFFRPTVLADCTHQMRVMTEETFGPLVGLAPFDDIDEVISRANDTPYGLAAYVYARDL 435
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ S ++ G V +NN AP+GG K SG+G E+G + + Y K +
Sbjct: 436 AAIHRLSAALDYGNVAINNVDASMMNAPYGGRKQSGVGYEHGREGLLEYFNFKHI 490
>UniRef50_Q7WFF4 Cluster: Putative aldehyde dehydrogenase; n=2;
Bordetella|Rep: Putative aldehyde dehydrogenase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 484
Score = 275 bits (674), Expect = 2e-72
Identities = 147/421 (34%), Positives = 226/421 (53%), Gaps = 2/421 (0%)
Query: 59 QRNSEWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRY 118
Q +W A +R +L + A LIE + LA + + +NG + L + +++ +
Sbjct: 58 QAFGDWARTTAWERADILQRAAALIEARRDRLAVVLTLENGKPLADSHGELDRVVETILW 117
Query: 119 LGSLADKIQGDTIPTDGDSFSYT-LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
+ G +P S + LK+PVG +PWN P ++ K+ A+AAGCTVV
Sbjct: 118 CAEEGKRTYGRVLPARAQRLSQSSLKRPVGPVAAFVPWNFPAVLAARKLAAAMAAGCTVV 177
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
+KPAE+TP +AG P GVVN++ G L P + K+SFTGS+ VG
Sbjct: 178 LKPAEETPAICIELVRAFVDAGTPAGVVNLLYGVPAQVSERLIASPIIRKVSFTGSVAVG 237
Query: 238 KLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYV 297
+L+ A +LK T+ELGG +P+++ +D D + + + GQ+C++ SR YV
Sbjct: 238 RLLASMAA-GHLKPATMELGGHAPVVVFDDVDADRVAKMCVGFKYRNAGQVCLSPSRFYV 296
Query: 298 QSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
I D+F + V +A +RVG+ +E GP + + L+E GA+L G
Sbjct: 297 HERIADRFAESFVRHAGLLRVGDGMEEGVQMGPLNNVRRLQAAERLVEQAVGAGASLALG 356
Query: 358 GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G RIG GY+ PTV V D I EE F PV I++F +++EVI RAN+ + GLAA
Sbjct: 357 GRRIGQRGYFYPPTVLEGVPDAADILAEEPFCPVAPIMRFGSMDEVIGRANHPSLGLAAY 416
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
FT + + +F++ +EAG + +NN++ AP GG KDSG+G E G + ++AYL +
Sbjct: 417 AFTNRMATSAEFAERIEAGWIGINNFVPALADAPIGGMKDSGLGYEGGPEGLDAYLHARF 476
Query: 478 V 478
V
Sbjct: 477 V 477
>UniRef50_A1B8X0 Cluster: Aldehyde dehydrogenase (NAD(+)); n=5;
Rhodobacterales|Rep: Aldehyde dehydrogenase (NAD(+)) -
Paracoccus denitrificans (strain Pd 1222)
Length = 776
Score = 275 bits (674), Expect = 2e-72
Identities = 168/454 (37%), Positives = 238/454 (52%), Gaps = 18/454 (3%)
Query: 20 KDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKF 79
+ G TF + P G +A+V +G QR W R + LY
Sbjct: 43 RPGVTFASRDPSTGDELAQVTQGTARDVMKAVRAARRA-QRG--WGAMPGHDRARFLYAI 99
Query: 80 ADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFS 139
A I++ +L+ LES DNG + I +P VR+ A + T+
Sbjct: 100 ARTIQKRERFLSVLESLDNGKPIRESRDI--DVPLVVRHFYHHAG--WAELAETE----- 150
Query: 140 YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAG 199
+ +P+GVCG ++PWN P+LM KV ALAAG TVV+KPAE TPLT G
Sbjct: 151 FPGHRPLGVCGQVIPWNFPLLMLAWKVAPALAAGNTVVLKPAEYTPLTALAFAEICAHVG 210
Query: 200 IPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGK 259
+P GVVNIV G GE G AL P V KI+FTGS EVG+ I +A + KR+TLELGGK
Sbjct: 211 LPAGVVNIVTGDGE-TGAALVRAP-VDKIAFTGSTEVGRGIARAVAGSG-KRLTLELGGK 267
Query: 260 SPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVG 319
SP +++ DADL+ A+ ++F+QG++C A SR+ V + +F + +R+G
Sbjct: 268 SPFVVLEDADLDAAVEGVVDSIWFNQGEVCCAGSRILVAESVAARFEALLRARMQKLRLG 327
Query: 320 NPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDD 379
P D+ST G +D +++L LI+ GA L+ G G +I P +++
Sbjct: 328 APLDKSTDIGAIVDPVQKDRILRLIDRATAAGAELVGGA---AAPGCFIAPGYLKNISPA 384
Query: 380 MTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVW 439
EEIFGP+ ++ F T +E +D ANNT YGLAA +++ + A + ++AG VW
Sbjct: 385 NPGMVEEIFGPIATLSTFRTPDEAVDLANNTRYGLAASVWSESATVATDLAARIKAGVVW 444
Query: 440 VNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
VN APFGG +DSG GRE G + + YL
Sbjct: 445 VNCANLFDAAAPFGGMRDSGYGREGGREGMLDYL 478
Score = 63.7 bits (148), Expect = 1e-08
Identities = 40/127 (31%), Positives = 57/127 (44%)
Query: 118 YLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV 177
+ ADK G T+ + +P GV GLI P P+ F+ V+ A+A G VV
Sbjct: 599 FYAGFADKYDGATVSAKPGHLCHVQPEPHGVMGLIAPVAAPLAGFMALVLPAIAMGNAVV 658
Query: 178 VKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVG 237
P++ P+ + +P GVVNIV G +D AL H V+ I G E
Sbjct: 659 AIPSQDRPMAALTLAQVLACSDVPGGVVNIVTGPRDDLVRALAGHDGVSAIWHAGLGEGL 718
Query: 238 KLIQKAA 244
+Q+ A
Sbjct: 719 AEVQRVA 725
>UniRef50_A0H764 Cluster: Aldehyde dehydrogenase; n=1; Comamonas
testosteroni KF-1|Rep: Aldehyde dehydrogenase -
Comamonas testosteroni KF-1
Length = 678
Score = 275 bits (674), Expect = 2e-72
Identities = 166/489 (33%), Positives = 258/489 (52%), Gaps = 17/489 (3%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
+K +I +W + +P V+A++++ + ++ W
Sbjct: 187 VKTITSYIGGQW-QPSGSQLLPIVNPATEEVVAQLSEADAGETGAAVAAAQASW-KSGVW 244
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNG--MVYKNCLRILSGIPDSVRYLGSL 122
++ + ++ ++ +L R + LA+LE ++G M Y N ++ P VR G
Sbjct: 245 AKQGSADKRRVFHRICELTLRHLDELAQLECLNSGLPMHYLNHRQL----PRIVRNFGFF 300
Query: 123 ADKIQGDTIP---TDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVK 179
AD + + +D D + L++P GV LI PWN P+ + K+ ALA G + VVK
Sbjct: 301 ADWLSQNVEKAGMSDQDYLRFVLREPAGVAALISPWNAPLALASTKIAAALAFGNSCVVK 360
Query: 180 PAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKL 239
AE TPL EAG+P GVVN+V G G G AL HP V +SFTG + G+
Sbjct: 361 TAETTPLAVARFMDILAEAGVPPGVVNMVNGRGHITGDALVRHPAVRVVSFTGGTQTGRA 420
Query: 240 IQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQS 299
I AA LKRV LELGGKS I+ A+L+ A+ A + ++ + GQ C A SR+ VQ
Sbjct: 421 I-AAAAAPGLKRVDLELGGKSANIVTETANLDDALDGALTSIYTNNGQQCFAGSRILVQR 479
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE 359
I D FV V+ A+AIRVG+P D GP + + ++V ++ +EG LL GG+
Sbjct: 480 SIADDFVARFVQRARAIRVGDPLDTRNELGPLSNAAHYSRVRSFVDIALQEGGTLLCGGK 539
Query: 360 R---IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAA 416
R IG GYY++PT ++ +EEIFGP ++ FD +E + AN++ +GL +
Sbjct: 540 RPAGIGDKGYYLEPTAVLMPHNRTRACQEEIFGPFATLQIFDDFDEALAIANDSEFGLVS 599
Query: 417 GIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAV-EAYLEE 475
+++ +L+ + +EAG V VN + + + PFGG+K+SG+GRE GI + Y EE
Sbjct: 600 YLWSNDLSQTQRAVCEIEAGVVLVNTPMILDLRFPFGGYKNSGLGRE-GIDGMRHFYTEE 658
Query: 476 KTVIISLPK 484
KTV ++L +
Sbjct: 659 KTVTLALKR 667
>UniRef50_A4YNG9 Cluster: Aldehyde dehydrogenase; NAD-linked; n=71;
cellular organisms|Rep: Aldehyde dehydrogenase;
NAD-linked - Bradyrhizobium sp. (strain ORS278)
Length = 495
Score = 274 bits (673), Expect = 3e-72
Identities = 167/476 (35%), Positives = 248/476 (52%), Gaps = 12/476 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K FI EWVD G T + + V+ + AK F W +
Sbjct: 19 KNFIAGEWVDGS-GVTRNINPSNTNDVVGEYAKADKAQTEKAIAAAKAAFPA---WSRST 74
Query: 69 ASQRGKLLYKF-ADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
+R L K A+++ R E L +L + + G + ++ + A ++
Sbjct: 75 PQERYDALNKISAEILSRK-EELGRLLAREEGKTLPEGIGEVARAGQIFAFFAGEALRLT 133
Query: 128 GDTIPTDGDSFSYTL-KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G+ + + ++ VGV G+I PWN PI + K+ AL G TVV KPAE P
Sbjct: 134 GEKGASVRPGLDVEITREAVGVVGMITPWNFPIAIPAWKIAPALCYGNTVVFKPAELVPG 193
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ +GIP GV N+V G G G L HPDVA ISFTGS+ G+ I +A
Sbjct: 194 SAHALSEIIARSGIPAGVFNLVVGSGSVVGQTLLEHPDVAAISFTGSVGTGRKIAQACVL 253
Query: 247 NN-LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+N +K+ LE+GGK+PL++++DAD+ +A+ A +G +F GQ C A+SRL V GI+DKF
Sbjct: 254 SNPMKKFQLEMGGKNPLVVLDDADVKVAVEAAANGAYFSTGQRCTASSRLIVTEGIHDKF 313
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--T 363
V E K + V + + T GP +D + + + ++ G+ EGA L GGE + +
Sbjct: 314 VAALTERLKGLVVDDAVKQGTHIGPVVDGNQLEQDQRYLKIGQDEGAKLAWGGELLNRES 373
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
G+Y+QP +F + N++M IA+EEIFGPV +++ +E + +N+T +GLAAG+ TT+L
Sbjct: 374 PGFYMQPALFTEANNNMRIAREEIFGPVACVIRAKNYDEALAISNDTEFGLAAGVCTTSL 433
Query: 424 NNALQFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGIG-RENGIKAVEAYLEEKT 477
A F ++ EAG V VN + + PFGG K S G RE G A E Y KT
Sbjct: 434 KYASHFKRNSEAGMVMVNLPTAGVDYHVPFGGRKGSSYGAREQGSYAREFYTTVKT 489
>UniRef50_A1CV82 Cluster: Succinate semialdehyde dehydrogenase;
n=18; Pezizomycotina|Rep: Succinate semialdehyde
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 530
Score = 274 bits (673), Expect = 3e-72
Identities = 163/493 (33%), Positives = 260/493 (52%), Gaps = 13/493 (2%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P + +T+ + ++AK G FD P G V A FQ
Sbjct: 41 PSLFHTRAYSHGTCIEAKGGGVFDVEDPGTGKVFASCPDLTVEDIEDVVQSSYKAFQ--- 97
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
+RL + R +LL K+ +LI + + LA + Y++G + +
Sbjct: 98 SYRLVNPRVRAQLLLKWHELICDNRDDLATILCYESGKPLVEAYAEIDYATGFTWWFAGE 157
Query: 123 ADKIQGD-TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
A++I+GD +IP+ + LKQP+GVC ++PWN P+ M L KV ALAAGCT++ KP+
Sbjct: 158 AERIRGDISIPSAPNRRVLVLKQPIGVCVALVPWNFPVAMILRKVGAALAAGCTMIAKPS 217
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGK 238
+TPLT +AG GV+N+V ++ AL HP V K+SFTGS ++G
Sbjct: 218 PETPLTALTLAYLAVKAGFAPGVLNVVTTSNKNTPSLSEALCKHPLVQKVSFTGSTKIGS 277
Query: 239 LIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQ 298
+I K LK+++LELGG P II +DAD A+ + + + GQ CV A+R+YVQ
Sbjct: 278 IIAKHC-AEGLKKLSLELGGNCPFIIFSDADQCQALAQLTALKWRNAGQACVTANRIYVQ 336
Query: 299 SGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG 358
IY++F+ V +A++I++G+ +S GP + KV +E + GA ++ GG
Sbjct: 337 EEIYEEFLTKLVGHARSIKLGHGSRDSVTMGPLTTIRGVEKVRRQVEDAVQRGAKVVHGG 396
Query: 359 ER-IGT---AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGL 414
+ + + GY+ +PT+ +N M I EE F P+ ++ F T EV AN+T+ GL
Sbjct: 397 KAPVASEFGCGYFFEPTIIRGMNSSMLITHEESFAPIAAVYSFRTEAEVTKLANDTDMGL 456
Query: 415 AAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIK-AVEAYL 473
A+ +FT +++ + +++E G + +N A + PFGG K SG G+E+G AV YL
Sbjct: 457 ASYVFTKDIDRCWRMLENLETGMIGLNTGNFSAAEIPFGGMKLSGYGKESGKDVAVAEYL 516
Query: 474 EEKTVIISLPKKL 486
KT +++ K++
Sbjct: 517 VSKTCTMTIEKEV 529
>UniRef50_Q15NZ3 Cluster: Betaine-aldehyde dehydrogenase; n=3;
Proteobacteria|Rep: Betaine-aldehyde dehydrogenase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 480
Score = 274 bits (672), Expect = 3e-72
Identities = 158/475 (33%), Positives = 244/475 (51%), Gaps = 9/475 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
LFID E+ A G+ +++P A V FQ W+
Sbjct: 6 LFIDGEYQQATSGKEDTSYNPATSEPYAVVQLASVQDATDAIASAHQAFQT---WKDVLP 62
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
S R K+L AD ER + L + G P +R + +++G+
Sbjct: 63 SVREKILLDIADAFERRADEFKDLLIDEAGSSMLKAGYETHHAPSFLRGMAGECRRVKGE 122
Query: 130 TIPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
T +D SY++++P+GV I P+N P+L+ + K+ ALAAG TVV+KP+E TP+
Sbjct: 123 TYQSDYPGLKSYSIRRPLGVVLSIAPFNFPLLLAIRKIGWALAAGNTVVLKPSEVTPVIA 182
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
E G+PKGV+N++P G + G L V K++FTGS VGK I A +
Sbjct: 183 LKLAEVMTEGGLPKGVLNVIPANGAELGDVLIADERVRKVTFTGSTRVGKSIALACAKYH 242
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
K +TLE+GGK+P I++ DAD++ A+ A F HQGQ+C+ SR+ V+ +YD+FV+
Sbjct: 243 -KPITLEMGGKNPFIVLADADVDYAVDAATFSNFMHQGQVCMTGSRVIVEDAVYDEFVRK 301
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYI 368
A+ GNP D + GP I + + +E ++GA + GG G
Sbjct: 302 FTAKVSALGYGNPRDPGVIVGPLIRPTQTEFIKKQVEKAVEQGAKINVGGHYEGNV---F 358
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
QPTV +DV DM+I E FGPV S++K + AN++ YGL + + T +L ++
Sbjct: 359 QPTVISDVTSDMSIFHTECFGPVASVIKASDYLHALALANDSEYGLTSAVITNDLQMSIF 418
Query: 429 FSKHVEAGTVWVNN-YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
FS+++E+G V +N + PFGG K+SG+GRE G A++ + E K + + +
Sbjct: 419 FSENLESGMVHINGPSIRDEAVVPFGGVKNSGMGREGGTFAMDEFTELKWITVQM 473
>UniRef50_Q6L285 Cluster: Succinate-semialdehyde dehydrogenase
[NADP+]; n=4; Thermoplasmatales|Rep:
Succinate-semialdehyde dehydrogenase [NADP+] -
Picrophilus torridus
Length = 493
Score = 274 bits (672), Expect = 3e-72
Identities = 151/478 (31%), Positives = 248/478 (51%), Gaps = 12/478 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K++ID EW D+ GET ++P G V+ F+R W
Sbjct: 2 KIYIDGEWRDSSSGETIKKYNPSTGEVLDTFPAATRNDVDAAIDSAEDAFKR---WSDMT 58
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+ +R K+LYK +LI +D + L L +NG V + + G+ D ++Y K+ G
Sbjct: 59 SMERSKILYKALELISKDKDQLTDLLIKENGKVKREAMDETEGVIDQLQYYTEFERKLTG 118
Query: 129 DTIP-TDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
D + T + K P G+ I PWN P M + K+ AL G TV++KP+ TPLT
Sbjct: 119 DIVEGTSNKRKIFQYKVPYGIVIAITPWNFPAAMVIRKLAPALLTGNTVILKPSSDTPLT 178
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+AGIPKGV+N++ G G + G + H V+ I+ TGS G+ I + A +
Sbjct: 179 AEWLVKKFVDAGIPKGVLNLITGKGSEIGDYIVEHKKVSLITMTGSTSTGQRIMEKA-SK 237
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
N+ ++ LELGGK+P ++ DA++ A+ + + GQ C+AA RLY+ IYD+F+K
Sbjct: 238 NMAKLILELGGKAPFMVWKDANIERALKSLVWAKYLNVGQSCIAAERLYIHEDIYDEFMK 297
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--- 364
+E +K I++G+P ES+ GP I++S + ++ + G +L GG++ +
Sbjct: 298 KFIEVSKRIKLGDP--ESSDMGPLINKSAVETTEKYVDIARSSGYKILLGGKKPELSGKY 355
Query: 365 --GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY+ +PT+ +V D + +EEIFGPV +++E+ ++AN++ YGLA+ +FT +
Sbjct: 356 KNGYFYEPTIIENVPQDSPLFQEEIFGPVIGAESVSSVDELYEKANDSKYGLASYLFTED 415
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+ S+ + G ++VN A Q GF+ +G E + YL+ K V +
Sbjct: 416 PELIFEASEKIRFGELYVNMPGPEASQGYHTGFRLTGQAGEGSKYGISEYLKLKNVYV 473
>UniRef50_Q0SCM9 Cluster: NAD-dependent aldehyde dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: NAD-dependent aldehyde
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 492
Score = 274 bits (671), Expect = 4e-72
Identities = 160/469 (34%), Positives = 236/469 (50%), Gaps = 11/469 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+ID WV ++ TF +P D VIA+V F ++WR + +
Sbjct: 23 YIDGGWVPSET--TFKALNPADEKVIAEVPASTATDVDAAVTAARRAF---ADWRHVNPT 77
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R + L+ D+++ LA+ + + G + + + + A +I G+
Sbjct: 78 VRARYLHTIGDIVKTRERELAEAITTEMGKTIGEATGEVDKLAKAFHFYAEEATRIHGEV 137
Query: 131 IPTDGDSF-SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
IP D D F S +++P+GV G I PWN P+ + K+ ALAAGCT+V+KP++ L+
Sbjct: 138 IPNDVDGFASMVVQEPIGVIGAITPWNYPLELVGWKLCAALAAGCTIVIKPSQYASLSPA 197
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAG+P GV N+V G GE G A+ HP K++FTGS G I A G
Sbjct: 198 LLFACIDEAGLPAGVANLVLGGGE-TGPAVAGHPGFDKLAFTGSTATGGKI--ARGVPAA 254
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
K +T+ELGG P+I+ + AD++ A+ A F + GQIC+A +R+YV +Y +FV
Sbjct: 255 KPLTMELGGSCPMIVTDRADIDAAVAGAARRGFRNAGQICIAINRIYVHETVYSEFVDRL 314
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--GYY 367
+ VGN D + GP + ++ V + GA + GG RI T G +
Sbjct: 315 TAKVSELTVGNGMDPTVDVGPMATRAGLDVVDQHVRDAIARGATVTTGGTRIETLAPGNF 374
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
QPTV A N DM + EE FGPV ++ F L +D AN T GLAA ++T +L A
Sbjct: 375 YQPTVIAGCNPDMLVMHEETFGPVVGVMPFSDLRNAVDLANGTEAGLAAYVYTGDLAQAH 434
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEK 476
+ ++ G V VNN AP+GG K SG G E+G +E YL+ K
Sbjct: 435 DLGRLLDFGNVAVNNVDAGIMNAPYGGRKGSGFGVEHGKAGLEGYLQYK 483
>UniRef50_Q0S5W5 Cluster: Probable betaine-aldehyde dehydrogenase;
n=1; Rhodococcus sp. RHA1|Rep: Probable betaine-aldehyde
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 493
Score = 274 bits (671), Expect = 4e-72
Identities = 162/482 (33%), Positives = 236/482 (48%), Gaps = 14/482 (2%)
Query: 6 KYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWR 65
+ T FI+ W + E P G I V W
Sbjct: 20 RVTGNFINGRWTPSNSPEIITVLDPSTGREIGTVPASSTADVDAAVAAARAA---QPGWA 76
Query: 66 LADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCL-RILSGIPDSVRYLGSLAD 124
+ R K L A + E ++ +E+ D G L G+ D++R+ A
Sbjct: 77 ALTPAARSKFLLDIATMTEELLAEISIVEAVDAGKPITAVRDEELPGVIDAMRFFAGAAR 136
Query: 125 KIQGDTIPTDGDSF----SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
+ P+ GD S ++P+GV I PWN P+L + KV ALA G T V+KP
Sbjct: 137 TLPA---PSSGDYLAGVSSIMRREPIGVAAGITPWNYPLLQAVAKVFPALATGNTYVLKP 193
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
AE TP + +P GV N+V G G AG AL HP V +SFTGS++ G+ +
Sbjct: 194 AETTPYSTAWLAEIVARV-LPDGVFNVVFGTGAVAGDALARHPKVDVVSFTGSIDTGRKV 252
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
AA + +K+ +ELGG SP+I+ DADL A+ +G ++ GQ C++ASR+ V +
Sbjct: 253 GIAAA-DGVKKAIMELGGNSPVIVFGDADLESALDAIATGGLYNTGQECMSASRVIVHAC 311
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
+ D FV G E ++G+ D +T GP ++VL I TG+ GA +++GGE
Sbjct: 312 LLDAFVDGLKERCSREKLGDVLDPTTTVGPMNSAQQRDRVLAKI-TGRSTGARVVSGGES 370
Query: 361 IGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
G++ PT+ V DD + +EEIFGPV ++ F+T E+ I AN T YGLA+ +FT
Sbjct: 371 CEGDGFFFPPTIVVGVADDEELVQEEIFGPVFTVQTFETEEQAIALANGTRYGLASSLFT 430
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+N+ A + + GTVWVNN+L A P GF SGIG EN + Y K V++
Sbjct: 431 SNVGTATRVQNALNFGTVWVNNHLVFAADLPVSGFGASGIGTENAEAGLLEYTRLKHVMV 490
Query: 481 SL 482
+
Sbjct: 491 DI 492
>UniRef50_Q5WBB9 Cluster: Aldehyde dehydrogenase; n=1; Bacillus
clausii KSM-K16|Rep: Aldehyde dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 483
Score = 273 bits (670), Expect = 6e-72
Identities = 159/477 (33%), Positives = 252/477 (52%), Gaps = 10/477 (2%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+ID EW + G F +P + I + N W+ A
Sbjct: 8 YIDGEWKPSISGNVFYGRNPANYEEILGAYQASTAEDARLAIKSAAAAFPN--WKNKSAI 65
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R +LY+ L+ + E LA + + + G + + ++++ A+++ G+T
Sbjct: 66 ERADVLYQLMPLLAAEKEKLAAIITKEVGKTMAAARKEVDASIQALKHFSGAANRLAGET 125
Query: 131 IPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
+P ++F+YT+K+P+G G+I P+N P+ + + K+ AL AG TVV KP T
Sbjct: 126 VPAGNPETFAYTIKEPLGPVGVITPFNFPLGIGIYKIAPALIAGNTVVYKPHNDTVQIAA 185
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
EAG PKGV+N+V G G+ G L + + ISFTGS +VG + ++ TN
Sbjct: 186 RLVELFIEAGTPKGVLNLVTGDGDKVGQELGENRTLKAISFTGSSDVGLRLGRSV-TNRG 244
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
++ E+GGK+ +I+ DADL+ A+ + GQ C SR+ V I
Sbjct: 245 GKMQAEMGGKNATVILEDADLDKAVSGIVISGLLNNGQSCTGTSRVIVPKNIAKTVTSKL 304
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI----GTAG 365
VE A AIRVG+ F+E+ NGP +E+ + K L ++ KEGA L GG+R+ G
Sbjct: 305 VEKATAIRVGDGFNENVENGPVANEAQLQKYLHYVDIAVKEGAKLECGGKRLFGEGKDKG 364
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNN 425
Y++ PTV + V +MTIA+EE+F PV +I++ D+ +E I AN T++GL++ I+TTNL
Sbjct: 365 YFVAPTVLSGVTPEMTIAQEEVFAPVVAIMEVDSFDEAIAVANQTDFGLSSAIYTTNLQK 424
Query: 426 ALQFSKHVEAGTVWVNNYLT-MAHQAPFGGFKDSGIG-RENGIKAVEAYLEEKTVII 480
A +F + VE G +N +Q PFGG K+S IG RE G A++ +++ K V +
Sbjct: 425 AHEFVRRVETGVTHINIPSNHYENQLPFGGKKNSSIGPREQGSTALDFWVDTKAVYL 481
>UniRef50_Q2G527 Cluster: Betaine-aldehyde dehydrogenase; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Betaine-aldehyde dehydrogenase - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 486
Score = 273 bits (670), Expect = 6e-72
Identities = 159/459 (34%), Positives = 245/459 (53%), Gaps = 8/459 (1%)
Query: 24 TFDTFSPHDGS-VIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADL 82
TF+T P D S +A +++G F W A++RG L++ ADL
Sbjct: 28 TFETRCPFDWSWKLADISRGTVTTAAQAAQAATDAFPA---WAALSAAERGAYLHRLADL 84
Query: 83 IERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYT 141
IE + E LA +E D GM+ ++ LR++ + R LA + + + + + +
Sbjct: 85 IEANVEKLAMIECLDMGMLLESLRLRVILRGAANFRNYADLATGHE-ERVWSSRGTLNRV 143
Query: 142 LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIP 201
++ P G +I PWN P ++ K ALAAG TV++KPA+ +PL+ +EAG P
Sbjct: 144 IRMPAGPALIITPWNAPFMLSTWKCAPALAAGNTVILKPADWSPLSASILADLIEEAGFP 203
Query: 202 KGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSP 261
GV NIV G G + G ALT P + +ISFTGS+ ++I KAA N+ +T ELGGKSP
Sbjct: 204 AGVFNIVQGLGAELGNALTSDPRIKRISFTGSVPTARVIGKAAA-ENIVPLTAELGGKSP 262
Query: 262 LIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNP 321
L++ DAD++ A A +G + GQ+C+A +R+ V+ + D+F+ YA A +G+
Sbjct: 263 LLVFADADIDAAAKKA-AGQYDDSGQVCMAGTRIIVEESVKDEFLAKFHAYADAHVMGDS 321
Query: 322 FDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMT 381
D +T I + +VLG IE + G ++ GG +I+PT+ N+
Sbjct: 322 RDAATTMSALIHPVHVERVLGFIERARAAGDAIVRGGRLWKEGSNWIEPTLIEPKNNQSE 381
Query: 382 IAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVN 441
+ + E+FGPV + F E + AN+T YGL+ ++T + A + + V GTVWVN
Sbjct: 382 VVQSEVFGPVLTFQTFRDEAEGVALANSTAYGLSGIVYTGSAERAERVGRQVRGGTVWVN 441
Query: 442 NYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
+L APFGG SGIGRE G A++ + + KT+ I
Sbjct: 442 TFLVRDLTAPFGGIGISGIGREGGDYALDFHSDLKTLQI 480
>UniRef50_Q13XQ3 Cluster: Aldehyde dehydrogenase; n=7;
Burkholderiales|Rep: Aldehyde dehydrogenase -
Burkholderia xenovorans (strain LB400)
Length = 485
Score = 273 bits (670), Expect = 6e-72
Identities = 159/477 (33%), Positives = 238/477 (49%), Gaps = 11/477 (2%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K I EW ++ G+TF +P D + V + Q ++WR
Sbjct: 9 KNLIAGEWTESVSGKTFANINPADTRDV--VGQFQASVVADAQAAIQAASSAFAQWRRTP 66
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
+ R +++ K AD +E + A+ + + G + +R+ A G
Sbjct: 67 VTARARIVNKAADWLESHADTFAQELTREEGKPLAQSRDEILRSAQVLRFYAVEAQSFTG 126
Query: 129 DTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+T P+D + YT ++P+GV +I PWN PI + K+ AL AG TV+ KP+ PL
Sbjct: 127 ETFPSDDPEQHVYTQREPLGVVTVITPWNFPISIPARKIAPALMAGNTVIFKPSSDAPLI 186
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+AGIP GV+N + G D G A+T P V ISFTGS G+ I ++
Sbjct: 187 GYRLAEAFAQAGIPAGVLNFITGRASDIGAAITESPVVRAISFTGSTAAGEHIHRSVPIT 246
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
R +ELGGK+PLI+M+DADL+ A+ A G GQ C SR+ V + + F
Sbjct: 247 T--RTQMELGGKNPLIVMDDADLDRAVDLAVKGGLSLSGQACTGTSRILVMESVRETFTA 304
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--- 364
VE K++++G+ GP + + VLG + +GK++ +L+ G + G
Sbjct: 305 KLVERVKSLKIGSGVTPGMDLGPLANRKQLESVLGYVASGKEQSTHLIGGEQLTGEGFEH 364
Query: 365 GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLN 424
GYY+ P VF+DV + I +EEIFGPV +I ++ I +AN+T YGL+A I T+N
Sbjct: 365 GYYVTPAVFSDVPESARIYREEIFGPVLAITSVTGYDDAIAKANDTEYGLSAAIATSNPR 424
Query: 425 NALQFSKHVEAGTVWVNNYLT-MAHQAPFGGFKDSGIG--RENGIKAVEAYLEEKTV 478
+F+ +EAGTV +N T APFGG K S RE+G +E Y + KTV
Sbjct: 425 YMHRFADEIEAGTVKINRTTTGNVINAPFGGLKRSSTSTFRESGRAGLEFYTQIKTV 481
>UniRef50_A0QIJ3 Cluster: Aldehyde dehydrogenase; n=4;
Mycobacterium|Rep: Aldehyde dehydrogenase -
Mycobacterium avium (strain 104)
Length = 487
Score = 273 bits (670), Expect = 6e-72
Identities = 151/427 (35%), Positives = 237/427 (55%), Gaps = 11/427 (2%)
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSL 122
EW +R LL+ ADL+ F L +L +D G+ + VRY
Sbjct: 64 EWISYPVDRRRDLLFGLADLLRDHFAELTELNVHDYGVPISVAGNSVL-TERFVRYYAGY 122
Query: 123 ADKIQGDTIPTDGDSFSYTL--KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
DK+ G + P G +F + ++P GV +I PWN P+++ V ALAAG V+ KP
Sbjct: 123 PDKLTGASTPVSG-AFDVNIVEREPYGVVAVIAPWNGPLVVAGAAVAPALAAGNAVIFKP 181
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
+E L EAG+P G+VN++P G + G AL HP V K+ FTG + +
Sbjct: 182 SELASLAPLRFGELCLEAGLPPGLVNVLPA-GPEGGEALVRHPGVGKVHFTGGHATAQQV 240
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAG-SGVFFHQGQICVAASRLYVQS 299
+AA ++N+ VT ELGGKS ++ DADL+ A A G GQ C ASR+ V++
Sbjct: 241 LRAA-SDNVTPVTAELGGKSAYLVFADADLDTAAVIAAHQGPLTQAGQSCACASRILVEA 299
Query: 300 GIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGA-NLLAGG 358
+Y FV+ V +A +G+P + GP I E+ +++LG+IE E A +L+ GG
Sbjct: 300 SVYVSFVEKLVAQVQAATIGDPLRPDVMLGPVITEAAADRILGVIERAVAEKAGDLVTGG 359
Query: 359 ERIG---TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLA 415
R+G +GY+I+PT+F++V++ ++A+ E FGPV S++ F + + AN++ YGL
Sbjct: 360 RRLGGELASGYFIEPTIFSNVDNRSSLAQTETFGPVASVMPFADEAQAVSLANDSRYGLN 419
Query: 416 AGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEE 475
A + T NL A + ++ ++AG+VWVN + + Q P+GG+K SG GR G++ + +L+
Sbjct: 420 AFVATANLERAHRVARRLQAGSVWVNRHSDIEPQGPYGGYKQSGFGRTGGVEGLHEFLQV 479
Query: 476 KTVIISL 482
K + I +
Sbjct: 480 KNIRIGM 486
>UniRef50_A0GW39 Cluster: Betaine-aldehyde dehydrogenase; n=2;
Chloroflexus|Rep: Betaine-aldehyde dehydrogenase -
Chloroflexus aggregans DSM 9485
Length = 486
Score = 273 bits (670), Expect = 6e-72
Identities = 161/472 (34%), Positives = 233/472 (49%), Gaps = 9/472 (1%)
Query: 10 LFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADA 69
+ I+ +W A G+ F +P VI V + F+ EWR A
Sbjct: 1 MLINGQWRAAAQGDVFPVHNPATEEVIDYVPRATAADAEQAMIAAEQAFR---EWRRTTA 57
Query: 70 SQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD 129
+ L++ A + E LA L + + G + Y L +G
Sbjct: 58 HDKAHALHEIAHKMRAHAEELATLLTLEGGKPLVENRDEIGWCAACFDYYAELQRNTRGR 117
Query: 130 TIPT-DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTX 188
IP+ + + LK+P GV I+PWN P+L+ KV ALAAG TVV+KP+E TPL
Sbjct: 118 VIPSVEPTQLAMVLKEPYGVVAAIVPWNYPLLLMSWKVAPALAAGNTVVLKPSEMTPLAT 177
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
+ +P GV+NI+ GFG D G L P I+FTGS G+ I + A
Sbjct: 178 LRFAELCCDH-LPAGVLNIITGFG-DVGRELVVSPRTQMIAFTGSFATGREIARLAA-ER 234
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+K+ LELGGK I+ DADL++A+P + GQ+C + R+YV I F +
Sbjct: 235 VKKTHLELGGKDAFIVAEDADLDVAVPGVAWAALLNAGQVCTSTERVYVHESIARPFTER 294
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG--TAGY 366
VE+ +++R+G D T GP I E KV +E + GA +L GG R T G+
Sbjct: 295 LVEFVRSLRLGPGMDPDTDIGPLIGEKYRAKVEDHVEEARARGATILTGGRRPPQFTRGF 354
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+ +PTV +V+ I +EE FGP I+ + T +E I+ N+ +YGL A ++T +
Sbjct: 355 FYEPTVLTNVDHSFRIMREETFGPTIPIMTYRTFDEAIELVNDCDYGLGANLYTNDPRKV 414
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
Q+ + V+AGT WVN+ LT PFGG K SG RE G + +E +LE K V
Sbjct: 415 KQYYEEVKAGTCWVNDPLTDNDAGPFGGMKFSGGARELGEEGLEEFLETKHV 466
>UniRef50_Q1B5L0 Cluster: Aldehyde dehydrogenase; n=18;
Actinomycetales|Rep: Aldehyde dehydrogenase -
Mycobacterium sp. (strain MCS)
Length = 495
Score = 273 bits (669), Expect = 8e-72
Identities = 160/488 (32%), Positives = 248/488 (50%), Gaps = 13/488 (2%)
Query: 5 IKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEW 64
++ +LFI W + SPH + + VA F W
Sbjct: 3 VRGDELFIGGTWCAPSTDRRIEVISPHTETTVGHVAAAAPADVDRAVGAAREAFDTGG-W 61
Query: 65 RLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLAD 124
+ R + + A ER +A+L + + G R +P S+ + + D
Sbjct: 62 PRTSPAGRIDAVRRLAANYERRRSEMAELITSEIGAPISFSQRAQVALPWSM--INAFCD 119
Query: 125 KIQG----DTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
Q + P S L++PVGV G ++PWN+P + + K++ AL AGCTVVVKP
Sbjct: 120 LAQTYPWREARPGRYGSDIQVLREPVGVVGAVVPWNMPQFLIVTKLIPALLAGCTVVVKP 179
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
A ++PL E+G+P GVV+++PG G G L H V K+SFTGS G+ +
Sbjct: 180 APESPLNALLLAEVIAESGLPPGVVSVLPGDGS-VGEYLVGHRGVDKVSFTGSTAAGRAV 238
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
A + L+RV+LELGGKS I+++DAD + S + GQIC A +R+ V
Sbjct: 239 ATACAAD-LRRVSLELGGKSAAIVLDDADPVVVAAGVRSASLSNSGQICNALTRVLVPRS 297
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
+F A+ VG+P D +T GP + +V G +E G ++GA ++ GG
Sbjct: 298 RAGEFTDALAAEVSALVVGDPTDGATQVGPLVARRQQQRVTGYLEQGVRDGARVVTGGTG 357
Query: 361 IGTA---GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
+ G+Y++PTVF ++ MTIA+EEIFGPV +++ +D +E + AN+++YGLA
Sbjct: 358 MPDGLDRGWYVKPTVFDRADNSMTIAREEIFGPVLTVVAYDNEDEAVAIANDSDYGLAGS 417
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT + + L + GT VN TM APFGG K SG GRE G + ++ Y++ K+
Sbjct: 418 VFTADTDRGLAVGAAIRTGTFGVNQGYTMDPFAPFGGVKSSGYGRELGREGIDGYVDTKS 477
Query: 478 VIISLPKK 485
+ ++ PK+
Sbjct: 478 ISVA-PKQ 484
>UniRef50_O66573 Cluster: Aldehyde dehydrogenase; n=1; Aquifex
aeolicus|Rep: Aldehyde dehydrogenase - Aquifex aeolicus
Length = 476
Score = 272 bits (668), Expect = 1e-71
Identities = 159/480 (33%), Positives = 249/480 (51%), Gaps = 15/480 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
K+ I EWVD + E + P+ I +V KG F+ E
Sbjct: 5 KMLIGGEWVDKE--EKIEVIYPYTRKPIGRVPKGDEKDVEKAIERAKEGFK---EIFSLT 59
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
A +R ++L + A L++ E AK + G + + ++ + A ++ G
Sbjct: 60 AYERYEILMRAAQLLKERAEEFAKTLVLEVGKTIREARTEVQRAIQTLIFSAEEAKRVNG 119
Query: 129 DTIPTDGD-----SFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+T P D + ++ PVG+ I P+N P+ + ++KV ALAAG V++KP+E+
Sbjct: 120 ETFPIDAHPNGKGKLGFYIRVPVGIVSAITPFNFPLNLSMHKVAPALAAGNAVILKPSER 179
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT EAG+P ++++PG+G D G A+T HPDV +SFTGS +VG +I +
Sbjct: 180 TPLTPLMLGEILLEAGVPPKALSVIPGYG-DVGKAMTTHPDVRVVSFTGSRKVGDIIARQ 238
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
G +K++ LELG S +I+ D +L A+ G + GQ+C++ R++V +YD
Sbjct: 239 VG---IKKLVLELGSNSAIILHKDGNLEKAVEKTVQGGYAIAGQVCISVQRVFVHEDLYD 295
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+F+K E ++VG+P +E T GP I S + ++ I ++GA + AGG R
Sbjct: 296 EFIKRLKERVSKLKVGDPMNEDTDLGPMIAPSELERIQEWISEAVQKGAKIEAGGLRCAE 355
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
PT+ + V +D + KEE F PV ++ + +EE I N+++YGL G+FT ++
Sbjct: 356 DETIFSPTIVSLVPEDSKLFKEEAFAPVVAVNPYKDIEEAIRWVNSSDYGLQVGVFTNDV 415
Query: 424 NNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
A + K +EAG V +N T A P+GG K SGIGRE A+E Y E KTVI L
Sbjct: 416 KLAWKCIKEIEAGGVLINEGPTFRADHMPYGGVKYSGIGREGPKFAIEDYTEIKTVIFDL 475
>UniRef50_Q3VZS3 Cluster: Betaine-aldehyde dehydrogenase; n=3;
Frankia|Rep: Betaine-aldehyde dehydrogenase - Frankia
sp. EAN1pec
Length = 487
Score = 272 bits (668), Expect = 1e-71
Identities = 164/484 (33%), Positives = 250/484 (51%), Gaps = 16/484 (3%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+L+ID W D+ + +P VI V G F W
Sbjct: 7 QLYIDGAWRDSDGDGVLEVLNPATEEVIGAVPDGTVSDVDRAVAAARRAFDEGP-WPTLS 65
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKI-- 126
A++R L + AD++ER + L +L + G + +P + + +A+++
Sbjct: 66 ANERATALLRMADVMERRVDELKELSVREAGSTRALADTLQVSVP--LHHFRDMAERVLR 123
Query: 127 ----QGDTIPTDGDSFSYTL--KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKP 180
+ +PT G + + + ++P GV LI +N P+ + + K+ ALAAGCTVV+KP
Sbjct: 124 QFPFERAMLPTVGPTLAQGVVRREPYGVAALISAYNFPLFLNILKLAPALAAGCTVVLKP 183
Query: 181 AEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLI 240
A TPL EAG+P GV+NIV G G AG ALT HP V +SFTGS VG+L+
Sbjct: 184 APTTPLEAFVLGEMADEAGLPPGVLNIVSG-GIAAGEALTTHPGVDIVSFTGSDTVGRLV 242
Query: 241 QKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSG 300
A +LK+V LELGGKS II D DL+L +P +G+ H GQ C +R V
Sbjct: 243 YTQAA-QSLKKVVLELGGKSANIITADVDLDLVVPTIVNGMTTHAGQGCSLLTRTLVHRS 301
Query: 301 IYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGER 360
D+ V + I VG+P D +T GP I + KV LI G+ EGA + GG R
Sbjct: 302 RLDELVGLVKQSLDHITVGDPADPATTMGPLISAAQRAKVESLISAGRAEGAQVAYGGGR 361
Query: 361 IG--TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGI 418
G++++PT+F DV++ MT+A++E FGPV ++ FD +E + AN++ +GL G+
Sbjct: 362 PAHLDKGFFVEPTLFVDVDNSMTVARKEFFGPVGVVIAFDDDDEAVRLANDSEFGLGGGV 421
Query: 419 FTTNLNNALQFSKHVEAGTVWVN-NYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+ + A + +K + G +++N + FGG+K SG+G E G +E +L K+
Sbjct: 422 WAQSPVRAYEIAKRLRTGMIYINGGGAGSSPHTAFGGYKQSGLGLERGEFGLEEFLLSKS 481
Query: 478 VIIS 481
+I S
Sbjct: 482 IIWS 485
>UniRef50_Q5HLA7 Cluster: Aldehyde dehydrogenase family protein;
n=5; Staphylococcus|Rep: Aldehyde dehydrogenase family
protein - Staphylococcus epidermidis (strain ATCC 35984
/ RP62A)
Length = 479
Score = 272 bits (667), Expect = 1e-71
Identities = 142/465 (30%), Positives = 241/465 (51%), Gaps = 5/465 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI+NE++D++ ET D +P G + Q EW
Sbjct: 9 QLFINNEFIDSQSKETMDVINPATGEAFDTITLATEEEVNDAIEKSQ---QAQLEWERVP 65
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQG 128
R + + L+E++ + +A+L + G + + Y+ SL+ +G
Sbjct: 66 QPTRAEHVKLLIPLLEKNRDEIAQLYVKEQGKTLTQAYGEIDKSISFIDYMTSLSMSDKG 125
Query: 129 DTIPTD-GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLT 187
+ + + +P+GV I+PWN PIL+ + KV+ A+ GC+VV+KP+E+T L
Sbjct: 126 RVLQNSIANETIQIINKPIGVTAGIVPWNAPILVLMRKVIPAIVTGCSVVIKPSEETTLL 185
Query: 188 XXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN 247
+ + IP G++ IVPG GE G L H D+ IS TGS+ GK + + A
Sbjct: 186 TVRLAELFRASTIPAGLIQIVPGTGETVGTQLASHKDIQLISLTGSMRAGKSVYENAA-Q 244
Query: 248 NLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVK 307
+K+V LELGG +P+I+ ++ADL+ A+ Y + + GQ+C R++V ++D F+
Sbjct: 245 TVKKVNLELGGNAPVIVTSNADLDKAVNYIVTARINNAGQVCTCPERIFVHEDVHDDFLN 304
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYY 367
K++ VG+PFDE+T G I++ ++ + ++ K GA L+ GG ++ G++
Sbjct: 305 KVTSKMKSLTVGDPFDENTDYGAIINQKQLDSIHEKVQDAIKNGATLMTGGHQLKRHGFF 364
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
PTV +V D + K+EIFGPV +I + E+VI+ AN+TN GL++ IF+ NL +
Sbjct: 365 YAPTVLDNVRKDDNVFKDEIFGPVLAITTYRDFEQVIEDANDTNAGLSSYIFSENLTEVM 424
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAY 472
++ ++ G V+ N G+++SG+G +GI E Y
Sbjct: 425 TATERLKFGEVYANCEAEEVVNGYHAGWRESGLGGADGIHGFEEY 469
>UniRef50_Q0S5S2 Cluster: Aldehyde dehydrogenase; n=2; Bacteria|Rep:
Aldehyde dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 486
Score = 272 bits (667), Expect = 1e-71
Identities = 158/477 (33%), Positives = 252/477 (52%), Gaps = 12/477 (2%)
Query: 12 IDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
I +W A G + +P ++A + F W+ A
Sbjct: 16 IGGQWGPADSGNWLEVENPARREILALIPDSGEADVNRAVAAAKDAF---GPWKALPARD 72
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR--ILSGIPDSVRYLGSLADKIQGD 129
RG LL K D I + E LA++ + + G + R SG D R+ G +A + +G+
Sbjct: 73 RGALLIKLGDKIAENQEELARIIASETGNALRTQARGEAASGA-DIFRFYGQIASEQKGE 131
Query: 130 TIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
T+P + SYT+++P+GV G I+PWN P+ + K+ ALA G T+V+K AE PL
Sbjct: 132 TLPFGENLVSYTVREPLGVVGGIVPWNAPVTLSSLKIAMALAMGNTLVLKTAELAPLAVL 191
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
E +P GV+N++ G G+ GV L+ HPDVAK++FTGS VGK I AA + +
Sbjct: 192 KLAEWAHEI-LPAGVLNVLTGSGQKVGVPLSKHPDVAKLTFTGSTGVGKEI-LAAAADRI 249
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGV-FFHQGQICVAASRLYVQSGIYDKFVKG 308
VTLELGGKSP I+ D+D + + +G+ F QGQ C A SRL + I+D F++
Sbjct: 250 VPVTLELGGKSPAIVFPDSDDDATVDGVIAGMRFTRQGQSCTAGSRLNLHEDIFDSFLEK 309
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG-ER-IGTAGY 366
++G+P DE+T G + E + V I +G +G ++ GG ER + G+
Sbjct: 310 LKNKLGQFKIGDPLDEATDIGAIVSEKQFDTVCRYITSGITQGGTVITGGPERPVDGDGF 369
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
++ PTV + D I +EE+FGPV ++ + ++V+ AN++ YGLA ++T ++ A
Sbjct: 370 FVAPTVITGADADWDITREEVFGPVLVVIPWKDEDQVLAAANDSTYGLAGYVWTKDITKA 429
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIK-AVEAYLEEKTVIISL 482
++ + +E G V +N +GG K SG+GRE + A+E++ + K + I++
Sbjct: 430 IRTANALEVGWVQINRGGGQLPGMSYGGIKQSGLGREYSVDGALESFTQVKNITIAV 486
>UniRef50_Q4WF71 Cluster: Aldehyde dehydrogenase family protein,
putative; n=6; Trichocomaceae|Rep: Aldehyde
dehydrogenase family protein, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 513
Score = 272 bits (667), Expect = 1e-71
Identities = 146/420 (34%), Positives = 231/420 (55%), Gaps = 4/420 (0%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W ADAS R +L K A L+ +LE+ G + L+ +P+ + Y SLA
Sbjct: 78 WSRADASDRFAVLSKAAALLRARIPEFVELETRQTGRPIREMRAQLARVPEWLEYSASLA 137
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+G P G + + P+GV I P+N P+L+ K+ ALA G V+VKP+E
Sbjct: 138 RVHEGRVTPFKGPVVNTLTRLPLGVVAQITPYNHPLLIATKKIAAALAGGNVVIVKPSEL 197
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
PL+ +EAG+P GV+ IV G+G + G +L +AKI TG L K I A
Sbjct: 198 APLSVLRLGPLFQEAGLPDGVLQIVSGYGSETGKSLCESRPLAKIDLTGGLATYKAIAPA 257
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N + +T ELGGK+P+ + D+ LA+ A F GQ CV SRL V + +YD
Sbjct: 258 AAANMIP-ITAELGGKAPVCLFPSLDVELAVKAAMFASFIASGQTCVTGSRLLVHADLYD 316
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+F + +A+RVG+P +E T G I + + + + +EG +L GG +
Sbjct: 317 RFKDLLEKRVRALRVGDPMEERTQIGSVISRAAVERCSAFVLRAVQEGGRVLCGGNPTNS 376
Query: 364 --AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PT+ + + D +A E+FGPV ++++ ++ EE+I AN+T+Y L A ++T
Sbjct: 377 NGKGFFFEPTII-ETHADSDLATNEVFGPVIALVRCESEEEIIRIANSTSYALGASVWTN 435
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+ + A + + +EAG VWVN + + +GGFK+SG+G+ENGI+A E+Y + K+ +I+
Sbjct: 436 DFSQAHRVAAKIEAGIVWVNGHHLNDPSSSWGGFKESGMGKENGIEAYESYTKVKSTVIN 495
>UniRef50_A5UKE4 Cluster: NADP-dependent glyceraldehyde-3-phosphate
dehydrogenase; n=2; Methanobacteriaceae|Rep:
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
- Methanobrevibacter smithii (strain PS / ATCC 35061 /
DSM 861)
Length = 470
Score = 272 bits (667), Expect = 1e-71
Identities = 151/413 (36%), Positives = 230/413 (55%), Gaps = 13/413 (3%)
Query: 76 LYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG 135
LY + ++ + + LA+L + + G + ++ ++++ A +I G+T+P DG
Sbjct: 64 LYAVYEKLKDNKDELAELLTKEVGKPINESVVEVNRSIETLKLSAEEAKRIYGETVPLDG 123
Query: 136 DS-----FSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
F++T + P+GV I P+N P+ + ++K+ A+A TV++KP PLT
Sbjct: 124 GINGKGFFAFTQRVPLGVVAAITPFNYPLNLSIHKIAPAIACKNTVIIKPPINAPLTVMK 183
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
E P GV+N V G+G + G AL P V KISFTGS+ G LI AG +K
Sbjct: 184 FAELVNEE-FPDGVINTVTGYGSEVGDALVTSPKVDKISFTGSVATGLLIASRAG---MK 239
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
+VTLELGG PL+++ DAD++ A+ +G + + GQ+C+ R+ V I D+F + V
Sbjct: 240 KVTLELGGNDPLVVLKDADIDRAVNGVMNGAYLNAGQVCMGVKRIIVDESIADEFTQKLV 299
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
K I++G+P D++TV G IDE V + K GA +L GG+R G + +
Sbjct: 300 RETKKIKMGDPMDKNTVLGTLIDEDAARMVEETVNNAVKAGAKILTGGKRDGA---FYEA 356
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV +V DM + E FGPV I+K + +E I AN+T YGL AG+FT N + L+ +
Sbjct: 357 TVLDNVTPDMDVVVNETFGPVAPIIKVKSTDEAIKVANDTEYGLQAGVFTENFRDGLRCA 416
Query: 431 KHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+EAGTV+VN T PFGGFK+SG G+E AVE +EK + ++L
Sbjct: 417 NEIEAGTVFVNKQSTFRTDNMPFGGFKNSGTGKEGVKYAVEEMTKEKLIGLNL 469
>UniRef50_A2SRP3 Cluster: Aldehyde dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Aldehyde
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 455
Score = 272 bits (666), Expect = 2e-71
Identities = 147/417 (35%), Positives = 225/417 (53%), Gaps = 5/417 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W AS+R + A L+ E LA L + + G + + G Y S++
Sbjct: 41 WEKTAASKRAVMFVNAASLMRARVEELAVLLTTEQGKPLREARDEILGSAHVFEYYASVS 100
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
I GD G + +++P+GVC I+PWN+P+++F K ALA G V+ KP++
Sbjct: 101 GSIPGDARNLPGYGYLNVVRKPLGVCAAIIPWNMPVMIFAWKAGAALACGNAVLAKPSKT 160
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
LT E G PK + IV G G +AG AL HPDV ISFTGS+ GK +
Sbjct: 161 ASLTILKIAEALYEGGFPKEALQIVTGSGGEAGAALVSHPDVRHISFTGSVVSGKAVSLL 220
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A +LK++TLELGG I+ AD++ A+ A F++ GQ+C +A R+ V + + D
Sbjct: 221 AAP-HLKKLTLELGGNDSFIVTKTADIDAAVKAAVRNRFYNCGQVCTSAKRILVDASLAD 279
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEG-ANLLAGGERIG 362
+FV A VGN ++ + GP + + ++ +E G A L+ GG+R+
Sbjct: 280 EFVHKAEVMLSGYVVGNGLEKVNM-GPVNNPDQLAQIEASVENILANGDAQLVYGGKRLE 338
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G + PT+ +V+ EEIFGPV S++ F+T +E +D AN+T YGL + ++TT+
Sbjct: 339 IPGNFYAPTLLKNVSP--LAVSEEIFGPVMSVIPFNTPDEALDIANSTQYGLGSSVWTTD 396
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
+ A F++ ++ G VWVN +LT+ + PFGG +SG GRENG V Y E K+++
Sbjct: 397 IGTARTFAESLKCGVVWVNKHLTLPPEMPFGGVGNSGFGRENGRDFVYEYTEPKSIL 453
>UniRef50_Q07IS5 Cluster: Aldehyde dehydrogenase; n=1;
Rhodopseudomonas palustris BisA53|Rep: Aldehyde
dehydrogenase - Rhodopseudomonas palustris (strain
BisA53)
Length = 484
Score = 271 bits (664), Expect = 3e-71
Identities = 157/471 (33%), Positives = 254/471 (53%), Gaps = 13/471 (2%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
G++ PH G IA+ + W +RG++L++ A+
Sbjct: 20 GDSLALLDPHSGRQIARFPRSGNAEIEAAVKAARSA---QPGWDAVPGVRRGEILHQIAN 76
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG-DSFSY 140
LIE + L+++ + + G + + R+ ++ G T+P+ ++
Sbjct: 77 LIEARSDELSRIVAAEAGKKLADARGEIGAAVQCARFFAGEGQRLFGRTMPSGMVGRWAM 136
Query: 141 TLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGI 200
T+++P GV GLI+ N P F KV AL G VV+K AE TP + +EAG+
Sbjct: 137 TIRRPCGVAGLIIAANTPAPNFAWKVFPALICGNAVVLKTAEDTPASSWLLGRLCEEAGL 196
Query: 201 PKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKS 260
PKGV+N+V G G +AG AL HPDV +SFTGS VG++I ++AG LK+V+LELGGK+
Sbjct: 197 PKGVLNVVHGLGPEAGQALIEHPDVDVLSFTGSTRVGRMIAESAG-RRLKKVSLELGGKN 255
Query: 261 PLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGN 320
L++ +DADL+LA+ ++ F + GQ C A SR+ V +Y +F + V AKA+++G
Sbjct: 256 ALVVCDDADLDLAVKWSLLAAFSNAGQRCAAGSRILVFDAVYPEFSEKLVSAAKALKLG- 314
Query: 321 PFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT---AGYYIQPTVFADVN 377
+E GP I++ ++ ++ IE GA+LL GG R + AG+Y+QPTV +D +
Sbjct: 315 -VEEDCDLGPVINQRQLDNMIAAIERAVGGGASLLCGGTRATSGEHAGFYMQPTVISDPD 373
Query: 378 DDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGT 437
+++ E+FGP+ ++ + ++ + N++ YGL A I T +++ AL F++ G
Sbjct: 374 PRSELSQTELFGPITALYRVSGFDQAVSVVNDSPYGLTASIHTRDIDRALSFARQAHVGV 433
Query: 438 VWVNNYLTMAH-QAPFGGFKDSGIG-RENGIKAVEAYLEEKTVII-SLPKK 485
VN + PFGG SG G RE G +A+E Y + + V + SLP +
Sbjct: 434 AVVNGGTHGSEPHMPFGGVNASGNGTREPGTEALEVYSDLRVVYLNSLPPR 484
>UniRef50_A0LMU4 Cluster: Aldehyde dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Aldehyde
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 480
Score = 270 bits (662), Expect = 5e-71
Identities = 165/474 (34%), Positives = 239/474 (50%), Gaps = 14/474 (2%)
Query: 16 WVDAK----DGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQ 71
W++ + DG + +P DGS I A W+ A +
Sbjct: 12 WIEGRNEPADGR-YPLVNPADGSCIGYAATADERLVTLALKSADRSL---GVWKSTPAPR 67
Query: 72 RGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTI 131
R +L++ A+L+ + L S + G ++ + + Y + ++ G I
Sbjct: 68 RAELMHALAELVRGHVDEFTSLVSTEVGKPVRSAKEEVLSAAGLIDYFAEESLRLTGQ-I 126
Query: 132 PTDGDSFSYTL--KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXX 189
P G + ++PVGV I P+N P+ K+ AL+ GCTVV+KP E TPL+
Sbjct: 127 PLLGYHREQVMIVREPVGVVVAITPYNYPLSTLACKIAPALSVGCTVVMKPDEHTPLSTL 186
Query: 190 XXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNL 249
AGIP+GV+N V G G G L +P I+FTGS EVGK I A+G +
Sbjct: 187 RLAQLACRAGIPEGVLNAVTGPGRPTGRLLVDNPVPRLITFTGSTEVGKEILMASG-RWV 245
Query: 250 KRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGA 309
++ LELGG P II +DA +P + GQ C SR YV IY F+
Sbjct: 246 RKTILELGGNCPAIICSDAPWEELLPQLLMQSMKNSGQYCYRVSRYYVAEEIYADFLAEF 305
Query: 310 VEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGE--RIGTAGYY 367
V A A+RVG+P GP + ++++V ++ KEGA ++ GG +IG AG++
Sbjct: 306 VAKAAALRVGHPASPEVDLGPLNNAGVLSRVRAQVDVAVKEGARVVLGGNDVKIGAAGFF 365
Query: 368 IQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNAL 427
PTV V+ M++ EEIFGPV I F +EEVI+ AN T +GLAA +FT ++ AL
Sbjct: 366 YPPTVLTGVDASMSVVGEEIFGPVVMIRPFKRIEEVIEAANATPFGLAAYLFTGDIAEAL 425
Query: 428 QFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+++ +E G+VWVN QAPFGG K+SG+GRE VE Y E KT+ +S
Sbjct: 426 KWANQLEVGSVWVNRIHQAYSQAPFGGMKESGLGREKSRFGVEEYTELKTIYLS 479
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.317 0.137 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 538,339,696
Number of Sequences: 1657284
Number of extensions: 22761504
Number of successful extensions: 49926
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 906
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 45883
Number of HSP's gapped (non-prelim): 1123
length of query: 486
length of database: 575,637,011
effective HSP length: 104
effective length of query: 382
effective length of database: 403,279,475
effective search space: 154052759450
effective search space used: 154052759450
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 74 (33.9 bits)
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