Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002457-TA|BGIBMGA002457-PA|IPR002086|Aldehyde
dehydrogenase, IPR012303|NAD-dependent aldehyde dehydrogenase
(486 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M31994-1|AAA51692.1| 501|Homo sapiens aldehyde dehydrogenase pr... 536 e-152
BT006921-1|AAP35567.1| 501|Homo sapiens aldehyde dehydrogenase ... 536 e-152
BC001505-1|AAH01505.1| 501|Homo sapiens aldehyde dehydrogenase ... 536 e-152
AY390731-1|AAR92229.1| 501|Homo sapiens aldehyde dehydrogenase ... 536 e-152
AY338497-1|AAP88039.1| 501|Homo sapiens aldehyde dehydrogenase ... 536 e-152
AL591031-1|CAI12257.1| 501|Homo sapiens aldehyde dehydrogenase ... 536 e-152
AF003341-1|AAC51652.1| 501|Homo sapiens aldehyde dehydrogenase ... 535 e-151
BC071839-1|AAH71839.1| 517|Homo sapiens aldehyde dehydrogenase ... 529 e-150
BC002967-1|AAH02967.1| 517|Homo sapiens aldehyde dehydrogenase ... 529 e-150
AY621070-1|AAT41621.1| 517|Homo sapiens mitochondrial aldehyde ... 529 e-150
CR456991-1|CAG33272.1| 517|Homo sapiens ALDH2 protein. 529 e-150
AK223373-1|BAD97093.1| 517|Homo sapiens mitochondrial aldehyde ... 529 e-150
M20456-1|AAA51693.1| 517|Homo sapiens aldehyde dehydrogenase pr... 528 e-149
Y00109-1|CAA68290.1| 515|Homo sapiens protein ( Human mRNA for ... 526 e-149
X05409-1|CAA28990.1| 516|Homo sapiens protein ( Human RNA for m... 524 e-148
DQ322171-1|ABC40749.1| 518|Homo sapiens aldehyde dehydrogenase ... 522 e-148
AB015226-1|BAA34785.1| 518|Homo sapiens RALDH2 protein. 522 e-148
U07919-1|AAA79036.1| 512|Homo sapiens aldehyde dehydrogenase 6 ... 520 e-147
BC069274-1|AAH69274.1| 512|Homo sapiens aldehyde dehydrogenase ... 520 e-147
AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase ... 516 e-146
BT007418-1|AAP36086.1| 517|Homo sapiens aldehyde dehydrogenase ... 515 e-145
BC001619-1|AAH01619.1| 517|Homo sapiens aldehyde dehydrogenase ... 515 e-145
M63967-1|AAA96830.1| 517|Homo sapiens aldehyde dehydrogenase pr... 512 e-144
AB015228-1|BAA34787.1| 422|Homo sapiens RALDH2-T protein. 479 e-135
AB015227-1|BAA34786.1| 422|Homo sapiens RALDH2-T protein. 479 e-135
M26760-1|AAA51694.1| 399|Homo sapiens aldehyde dehydrogenase II... 452 e-127
K03001-1|AAB59500.1| 399|Homo sapiens ALDH2 protein. 452 e-127
BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase ... 438 e-122
AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate ... 433 e-121
AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate ... 433 e-121
AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase ... 431 e-120
AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofola... 429 e-120
M26761-1|AAA35518.1| 340|Homo sapiens aldehyde dehydrogenase I ... 409 e-113
K03000-1|AAA51695.1| 340|Homo sapiens ALDH1 protein. 409 e-113
BX538027-1|CAD97973.1| 416|Homo sapiens hypothetical protein pr... 350 6e-96
AB209821-1|BAD93058.1| 330|Homo sapiens aldehyde dehydrogenase ... 327 5e-89
X75425-1|CAA53176.1| 462|Homo sapiens aldehyde dehydrogenase (N... 319 2e-86
U50203-1|AAB06721.1| 466|Homo sapiens aldehyde dehydrogenase E3... 319 2e-86
U34252-1|AAB18827.1| 493|Homo sapiens gamma-aminobutyraldehyde ... 319 2e-86
AL451074-5|CAH74061.1| 518|Homo sapiens aldehyde dehydrogenase ... 319 2e-86
AF172093-1|AAF43600.1| 494|Homo sapiens 4-trimethylaminobutyral... 319 2e-86
BC030589-1|AAH30589.1| 480|Homo sapiens aldehyde dehydrogenase ... 303 8e-82
M54931-1|AAA62825.1| 287|Homo sapiens aldehyde dehydrogenase I ... 294 4e-79
Y11192-1|CAA72076.1| 535|Homo sapiens succinic semialdehyde deh... 294 5e-79
BC113862-1|AAI13863.1| 487|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
BC034321-1|AAH34321.1| 535|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
AL445190-1|CAI95158.1| 487|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
AL031230-4|CAA20248.1| 535|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
AL021939-1|CAI20305.1| 487|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
AJ427355-1|CAD20884.1| 535|Homo sapiens succinic semialdehyde d... 294 5e-79
AF303134-1|AAG42417.1| 487|Homo sapiens aldehyde dehydrogenase ... 294 5e-79
AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens ... 279 2e-74
BC103935-1|AAI03936.1| 488|Homo sapiens ALDH1L2 protein protein. 276 1e-73
AJ427354-1|CAD20883.2| 480|Homo sapiens succinic semialdehyde d... 274 6e-73
L34820-1|AAA67057.1| 323|Homo sapiens succinate semialdehyde de... 239 1e-62
AL591031-3|CAI12260.1| 238|Homo sapiens aldehyde dehydrogenase ... 225 3e-58
AK124908-1|BAC85992.1| 470|Homo sapiens protein ( Homo sapiens ... 222 2e-57
AL591031-2|CAI12259.1| 230|Homo sapiens aldehyde dehydrogenase ... 215 4e-55
AK223244-1|BAD96964.1| 535|Homo sapiens aldehyde dehydrogenase ... 210 6e-54
BC032371-1|AAH32371.1| 535|Homo sapiens aldehyde dehydrogenase ... 209 2e-53
BC004909-1|AAH04909.1| 535|Homo sapiens aldehyde dehydrogenase ... 209 2e-53
AJ249994-1|CAB76468.1| 535|Homo sapiens methylmalonate semialde... 209 2e-53
AF159889-1|AAF80380.1| 535|Homo sapiens methylmalonate semialde... 209 2e-53
AF148855-1|AAG29581.1| 535|Homo sapiens methylmalonate-semialde... 209 2e-53
AF148505-1|AAF04489.1| 535|Homo sapiens methylmalonate-semialde... 209 2e-53
AK222687-1|BAD96407.1| 535|Homo sapiens aldehyde dehydrogenase ... 208 4e-53
BC002515-1|AAH02515.3| 511|Homo sapiens aldehyde dehydrogenase ... 194 8e-49
S74728-1|AAB31966.1| 511|Homo sapiens antiquitin protein. 193 1e-48
BC073174-1|AAH73174.1| 511|Homo sapiens aldehyde dehydrogenase ... 193 1e-48
BC071712-1|AAH71712.1| 511|Homo sapiens aldehyde dehydrogenase ... 193 1e-48
M93405-1|AAA36328.1| 430|Homo sapiens methylmalonate semialdehy... 191 4e-48
AL591031-4|CAI12261.1| 203|Homo sapiens aldehyde dehydrogenase ... 186 2e-46
AL445190-2|CAI95159.1| 433|Homo sapiens aldehyde dehydrogenase ... 147 7e-35
AL021939-2|CAI20306.1| 433|Homo sapiens aldehyde dehydrogenase ... 147 7e-35
S61044-1|AAB26658.1| 453|Homo sapiens aldehyde dehydrogenase is... 146 2e-34
M77477-1|AAB46377.1| 453|Homo sapiens aldehyde dehydrogenase pr... 146 2e-34
M74542-1|AAA51696.1| 453|Homo sapiens aldehyde dehydrogenase ty... 145 3e-34
BT007102-1|AAP35766.1| 453|Homo sapiens aldehyde dehydrogenase ... 145 3e-34
BC021194-1|AAH21194.1| 453|Homo sapiens aldehyde dehydrogenase ... 145 3e-34
BC008892-1|AAH08892.1| 453|Homo sapiens aldehyde dehydrogenase ... 145 3e-34
BC004370-1|AAH04370.1| 453|Homo sapiens aldehyde dehydrogenase ... 145 3e-34
BC004102-1|AAH04102.1| 512|Homo sapiens ALDH3A1 protein protein. 145 3e-34
AK222848-1|BAD96568.1| 433|Homo sapiens aldehyde dehydrogenase ... 144 5e-34
U75296-1|AAC50966.1| 485|Homo sapiens fatty aldehyde dehydrogen... 136 2e-31
U75295-1|AAC50965.1| 508|Homo sapiens fatty aldehyde dehydrogen... 136 2e-31
U46689-1|AAC51121.1| 485|Homo sapiens aldehyde dehydrogenase pr... 136 2e-31
L47162-1|AAB01003.1| 485|Homo sapiens fatty aldehyde dehydrogen... 136 2e-31
CR457422-1|CAG33703.1| 485|Homo sapiens ALDH3A2 protein. 136 2e-31
BC002430-1|AAH02430.1| 508|Homo sapiens aldehyde dehydrogenase ... 136 2e-31
AB208894-1|BAD92131.1| 461|Homo sapiens aldehyde dehydrogenase ... 136 2e-31
AK222486-1|BAD96206.1| 563|Homo sapiens aldehyde dehydrogenase ... 133 1e-30
U24267-1|AAC50501.1| 563|Homo sapiens pyrroline-5-carboxylate d... 132 3e-30
U24266-1|AAC50500.1| 563|Homo sapiens pyrroline-5-carboxylate d... 132 3e-30
BC023600-1|AAH23600.1| 563|Homo sapiens aldehyde dehydrogenase ... 132 3e-30
AL954340-2|CAI39493.1| 563|Homo sapiens aldehyde dehydrogenase ... 132 3e-30
AL080251-1|CAI23417.1| 563|Homo sapiens aldehyde dehydrogenase ... 132 3e-30
BC007581-1|AAH07581.1| 563|Homo sapiens aldehyde dehydrogenase ... 132 4e-30
BT006810-1|AAP35456.1| 385|Homo sapiens aldehyde dehydrogenase ... 131 5e-30
BC007685-1|AAH07685.1| 385|Homo sapiens aldehyde dehydrogenase ... 131 5e-30
U37519-1|AAA85441.1| 385|Homo sapiens aldehyde dehydrogenase pr... 128 3e-29
AK092464-1|BAC03897.1| 385|Homo sapiens protein ( Homo sapiens ... 128 3e-29
U10868-1|AAA83428.1| 468|Homo sapiens ALDH7 protein. 127 8e-29
EF411198-1|ABN58743.1| 468|Homo sapiens aldehyde dehydrogenase ... 127 8e-29
BT009832-1|AAP88834.1| 468|Homo sapiens aldehyde dehydrogenase ... 127 8e-29
BC013584-1|AAH13584.1| 468|Homo sapiens aldehyde dehydrogenase ... 127 8e-29
AB209651-1|BAD92888.1| 447|Homo sapiens aldehyde dehydrogenase ... 127 8e-29
BC033099-1|AAH33099.1| 431|Homo sapiens aldehyde dehydrogenase ... 127 1e-28
AJ427353-1|CAD20882.1| 222|Homo sapiens succinate semialdehyde ... 124 5e-28
AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens ... 123 1e-27
BC014895-1|AAH14895.2| 802|Homo sapiens aldehyde dehydrogenase ... 120 1e-26
BC114473-1|AAI14474.1| 265|Homo sapiens ALDH8A1 protein protein. 116 2e-25
BC070030-1|AAH70030.1| 253|Homo sapiens ALDH9A1 protein protein. 109 3e-23
BC045645-1|AAH45645.1| 267|Homo sapiens ALDH1L1 protein protein. 93 2e-18
AK074136-1|BAB84962.1| 358|Homo sapiens FLJ00209 protein protein. 74 1e-12
BC014168-1|AAH14168.2| 159|Homo sapiens ALDH3B1 protein protein. 58 5e-08
BC042142-1|AAH42142.1| 481|Homo sapiens ALDH16A1 protein protein. 58 7e-08
BC002553-1|AAH02553.1| 230|Homo sapiens ALDH3B1 protein protein. 58 9e-08
BC035641-1|AAH35641.1| 216|Homo sapiens ALDH16A1 protein protein. 54 1e-06
BC027241-1|AAH27241.1| 505|Homo sapiens ALDH1L1 protein protein. 51 1e-05
AK124965-1|BAC86008.1| 131|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AF164120-1|AAD48447.1| 38|Homo sapiens mitochondrial aldehyde ... 41 0.008
AB015229-1|BAA34788.1| 25|Homo sapiens RALDH2-T protein. 34 0.97
BC113400-1|AAI13401.1| 476|Homo sapiens chromosome 20 open read... 33 3.0
BC113398-1|AAI13399.1| 476|Homo sapiens chromosome 20 open read... 33 3.0
AL121756-8|CAI22531.1| 476|Homo sapiens chromosome 20 open read... 33 3.0
AF549189-1|AAP84989.1| 476|Homo sapiens RYA3 protein. 33 3.0
BC035627-1|AAH35627.1| 523|Homo sapiens solute carrier family 7... 32 5.2
AJ277731-1|CAC81900.1| 523|Homo sapiens ASC1 protein protein. 32 5.2
AF340165-1|AAK93960.1| 523|Homo sapiens amino acid transporter ... 32 5.2
AB037670-1|BAB03213.1| 523|Homo sapiens asc-type amino acid tra... 32 5.2
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 31 6.9
AL590438-3|CAH71529.1| 1257|Homo sapiens PR domain containing 16... 31 9.1
AL590438-2|CAH71531.1| 1276|Homo sapiens PR domain containing 16... 31 9.1
AL512383-3|CAH71133.1| 1257|Homo sapiens PR domain containing 16... 31 9.1
AL512383-2|CAH71132.1| 1276|Homo sapiens PR domain containing 16... 31 9.1
AL354743-3|CAI22789.1| 1257|Homo sapiens PR domain containing 16... 31 9.1
AL354743-1|CAI22788.1| 1276|Homo sapiens PR domain containing 16... 31 9.1
AL008733-3|CAI19631.1| 1257|Homo sapiens PR domain containing 16... 31 9.1
AL008733-1|CAI19630.1| 1276|Homo sapiens PR domain containing 16... 31 9.1
AB078876-1|BAB84297.1| 1257|Homo sapiens transcription factor ME... 31 9.1
AB051462-1|BAB21766.2| 1286|Homo sapiens KIAA1675 protein protein. 31 9.1
>M31994-1|AAA51692.1| 501|Homo sapiens aldehyde dehydrogenase
protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>BT006921-1|AAP35567.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>BC001505-1|AAH01505.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>AY390731-1|AAR92229.1| 501|Homo sapiens aldehyde dehydrogenase 1
A1 protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>AY338497-1|AAP88039.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>AL591031-1|CAI12257.1| 501|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 501
Score = 536 bits (1322), Expect = e-152
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>AF003341-1|AAC51652.1| 501|Homo sapiens aldehyde dehydrogenase 1
protein.
Length = 501
Score = 535 bits (1321), Expect = e-151
Identities = 258/483 (53%), Positives = 335/483 (69%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 256
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++V+ IY
Sbjct: 257 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIY 316
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
D+FV+ +VE AK +GNP GPQID+ +K+L LIE+GKKEGA L GG G
Sbjct: 317 DEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWG 376
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
GY++QPTVF++V D+M IAKEEIFGPVQ I+KF +L++VI RANNT YGL+AG+FT +
Sbjct: 377 NKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKD 436
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
++ A+ S ++AGTVWVN Y ++ Q PFGGFK SG GRE G Y E KTV + +
Sbjct: 437 IDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKI 496
Query: 483 PKK 485
+K
Sbjct: 497 SQK 499
>BC071839-1|AAH71839.1| 517|Homo sapiens aldehyde dehydrogenase 2
family (mitochondrial) protein.
Length = 517
Score = 529 bits (1306), Expect = e-150
Identities = 266/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>BC002967-1|AAH02967.1| 517|Homo sapiens aldehyde dehydrogenase 2
family (mitochondrial) protein.
Length = 517
Score = 529 bits (1306), Expect = e-150
Identities = 266/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>AY621070-1|AAT41621.1| 517|Homo sapiens mitochondrial aldehyde
dehydrogenase 2 protein.
Length = 517
Score = 529 bits (1306), Expect = e-150
Identities = 266/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDQTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>CR456991-1|CAG33272.1| 517|Homo sapiens ALDH2 protein.
Length = 517
Score = 529 bits (1305), Expect = e-150
Identities = 266/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPFTGEVICQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQLDETQFKKILGYINTGKQEGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>AK223373-1|BAD97093.1| 517|Homo sapiens mitochondrial aldehyde
dehydrogenase 2 precursor variant protein.
Length = 517
Score = 529 bits (1305), Expect = e-150
Identities = 265/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G V+ +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVVCQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>M20456-1|AAA51693.1| 517|Homo sapiens aldehyde dehydrogenase
protein.
Length = 517
Score = 528 bits (1303), Expect = e-149
Identities = 265/484 (54%), Positives = 325/484 (67%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 32 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAARAAFQLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 92 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 152 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 212 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 272 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV+ +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK++GA LL GG
Sbjct: 332 YDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQQGAKLLCGGGIA 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 392 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 452 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>Y00109-1|CAA68290.1| 515|Homo sapiens protein ( Human mRNA for
mitochondrial aldehyde dehydrogenase (ALDH I). ).
Length = 515
Score = 526 bits (1299), Expect = e-149
Identities = 266/484 (54%), Positives = 324/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 30 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGS 89
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS RG+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 90 PWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 149
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 150 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 209
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 210 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 269
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 270 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 329
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 330 YDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 389
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 390 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 449
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 450 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 509
Query: 482 LPKK 485
+P+K
Sbjct: 510 VPQK 513
>X05409-1|CAA28990.1| 516|Homo sapiens protein ( Human RNA for
mitochondrial aldehyde dehydrogenase I ALDH I (EC
1.2.1.3). ).
Length = 516
Score = 524 bits (1293), Expect = e-148
Identities = 265/484 (54%), Positives = 323/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
PE+ ++FI+NEW DA +TF T +P G VI +VA+G FQ S
Sbjct: 31 PEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAREGRPGAFQLGS 90
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYK-NCLRILSGIPDSVRYLGS 121
WR DAS G+LL + ADLIERD YLA LE+ DNG Y + L L + +RY
Sbjct: 91 PWRRMDASHSGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVLKCLRYYAG 150
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DGD FSYT +PVGVCG I+PWN P+LM K+ ALA G VV+K A
Sbjct: 151 WADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVA 210
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPLT KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ
Sbjct: 211 EQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQ 270
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
AAG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ I
Sbjct: 271 VAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDI 330
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
YD+FV +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 331 YDEFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIA 390
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
GY+IQPTVF DV D MTIAKEEIFGPV ILKF T+EEV+ RANN+ YGLAA +FT
Sbjct: 391 ADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTK 450
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A S+ ++AGTVWVN Y Q+PFGG+K SG GRE G ++AY E KTV +
Sbjct: 451 DLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVK 510
Query: 482 LPKK 485
+P+K
Sbjct: 511 VPQK 514
>DQ322171-1|ABC40749.1| 518|Homo sapiens aldehyde dehydrogenase 1
family, member A2 protein.
Length = 518
Score = 522 bits (1289), Expect = e-148
Identities = 250/483 (51%), Positives = 328/483 (67%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
EIKYTK+FI+NEW +++ G F ++P G + +V + F S
Sbjct: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
WR DAS+RG+LL K ADL+ERD LA +ES + G + + L G+ + RY
Sbjct: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKI G TIP DGD F++T +P+GVCG I+PWN P+LMF K+ AL G TVV+KPAE
Sbjct: 154 ADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPL+ KEAG P GV+NI+PG+G AG A+ H + KI+FTGS EVGKLIQ+
Sbjct: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP II DADL+ A+ A GVFF+QGQ C A SR++V+ IY
Sbjct: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
++FV+ +VE AK VG+PFD +T GPQID+ NK+L LI++G EGA L GG+ +G
Sbjct: 334 EEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G++I+PTVF++V DDM IAKEEIFGPVQ IL+F T++EVI+RANN+++GL A +FT +
Sbjct: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+N AL S ++AGTVW+N Y + Q+PFGGFK SG GRE G + Y E KTV + +
Sbjct: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513
Query: 483 PKK 485
P+K
Sbjct: 514 PQK 516
>AB015226-1|BAA34785.1| 518|Homo sapiens RALDH2 protein.
Length = 518
Score = 522 bits (1289), Expect = e-148
Identities = 250/483 (51%), Positives = 328/483 (67%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
EIKYTK+FI+NEW +++ G F ++P G + +V + F S
Sbjct: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
WR DAS+RG+LL K ADL+ERD LA +ES + G + + L G+ + RY
Sbjct: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKI G TIP DGD F++T +P+GVCG I+PWN P+LMF K+ AL G TVV+KPAE
Sbjct: 154 ADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPL+ KEAG P GV+NI+PG+G AG A+ H + KI+FTGS EVGKLIQ+
Sbjct: 214 QTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQE 273
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AAG +NLKRVTLELGGKSP II DADL+ A+ A GVFF+QGQ C A SR++V+ IY
Sbjct: 274 AAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIY 333
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
++FV+ +VE AK VG+PFD +T GPQID+ NK+L LI++G EGA L GG+ +G
Sbjct: 334 EEFVRRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLG 393
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G++I+PTVF++V DDM IAKEEIFGPVQ IL+F T++EVI+RANN+++GL A +FT +
Sbjct: 394 RKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTND 453
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
+N AL S ++AGTVW+N Y + Q+PFGGFK SG GRE G + Y E KTV + +
Sbjct: 454 INKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKI 513
Query: 483 PKK 485
P+K
Sbjct: 514 PQK 516
>U07919-1|AAA79036.1| 512|Homo sapiens aldehyde dehydrogenase 6
protein.
Length = 512
Score = 520 bits (1282), Expect = e-147
Identities = 256/483 (53%), Positives = 328/483 (67%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E+K+TK+FI+NEW ++K G+ F T +P I +V +G FQR S
Sbjct: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
WR DA RG+LL++ ADL+ERD LA LE+ D G + + I L G ++RY
Sbjct: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIPTD + +T +P+GVCG I PWN P+LM + K+ AL G T+V+KPAE
Sbjct: 148 ADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPGFG G A++ HP + KI+FTGS EVGKL+++
Sbjct: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AA +NLKRVTLELGGK+P I+ DADL+LA+ A GVFF+QGQ C AASR++V+ +Y
Sbjct: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+FV+ +VEYAK VG+PFD T GPQID+ +K+L LIE+GKKEGA L GG +
Sbjct: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G +I+PTVF++V D+M IAKEEIFGPVQ ILKF ++EEVI RAN+T+YGL A +FT N
Sbjct: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ AL+ + +E+GTVW+N Y + QAPFGGFK SG GRE G A+ Y E KTV I L
Sbjct: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507
Query: 483 PKK 485
K
Sbjct: 508 GDK 510
>BC069274-1|AAH69274.1| 512|Homo sapiens aldehyde dehydrogenase 1
family, member A3 protein.
Length = 512
Score = 520 bits (1282), Expect = e-147
Identities = 256/483 (53%), Positives = 328/483 (67%), Gaps = 1/483 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E+K+TK+FI+NEW ++K G+ F T +P I +V +G FQR S
Sbjct: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
WR DA RG+LL++ ADL+ERD LA LE+ D G + + I L G ++RY
Sbjct: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIPTD + +T +P+GVCG I PWN P+LM + K+ AL G T+V+KPAE
Sbjct: 148 ADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPGFG G A++ HP + KI+FTGS EVGKL+++
Sbjct: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIY 302
AA +NLKRVTLELGGK+P I+ DADL+LA+ A GVFF+QGQ C AASR++V+ +Y
Sbjct: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327
Query: 303 DKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
+FV+ +VEYAK VG+PFD T GPQID+ +K+L LIE+GKKEGA L GG +
Sbjct: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
G +I+PTVF++V D+M IAKEEIFGPVQ ILKF ++EEVI RAN+T+YGL A +FT N
Sbjct: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISL 482
L+ AL+ + +E+GTVW+N Y + QAPFGGFK SG GRE G A+ Y E KTV I L
Sbjct: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507
Query: 483 PKK 485
K
Sbjct: 508 GDK 510
>AL135785-2|CAD13246.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 516 bits (1274), Expect = e-146
Identities = 251/484 (51%), Positives = 321/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I Y +LFI+NEW DA +TF T +P G VI VA+G F+ S
Sbjct: 32 PDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
WR DAS+RG+LL + ADL+ERD YLA LE+ DNG ++ + L + RY
Sbjct: 92 PWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DG F +T +PVGVCG I+PWN P++M K+ ALA G TVV+K A
Sbjct: 152 WADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPL+ KEAG P GVVNI+ G+G AG A+ H DV K++FTGS EVG LIQ
Sbjct: 212 EQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
KAAG +NLKRVTLELGGKSP I++ DAD+ A+ +FF+ GQ C A SR +V+ I
Sbjct: 272 KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y++F++ VE AK +VGNPF+ T GPQ+D+ +VLG I+ G+KEGA LL GGER
Sbjct: 332 YNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++I+PTVF V DDM IAKEEIFGPVQ + KF +EEV++RANNT YGLAA +FT
Sbjct: 392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A+ F++ ++AGTVWVN Y + PFGGFK+SG GRE G ++AY E KTV I
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>BT007418-1|AAP36086.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 515 bits (1270), Expect = e-145
Identities = 251/484 (51%), Positives = 320/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I Y +LFI+NEW DA +TF T +P G VI VA+G F+ S
Sbjct: 32 PDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
WR DAS+RG+LL ADL+ERD YLA LE+ DNG ++ + L + RY
Sbjct: 92 PWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DG F +T +PVGVCG I+PWN P++M K+ ALA G TVV+K A
Sbjct: 152 WADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPL+ KEAG P GVVNI+ G+G AG A+ H DV K++FTGS EVG LIQ
Sbjct: 212 EQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
KAAG +NLKRVTLELGGKSP I++ DAD+ A+ +FF+ GQ C A SR +V+ I
Sbjct: 272 KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y++F++ VE AK +VGNPF+ T GPQ+D+ +VLG I+ G+KEGA LL GGER
Sbjct: 332 YNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++I+PTVF V DDM IAKEEIFGPVQ + KF +EEV++RANNT YGLAA +FT
Sbjct: 392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A+ F++ ++AGTVWVN Y + PFGGFK+SG GRE G ++AY E KTV I
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>BC001619-1|AAH01619.1| 517|Homo sapiens aldehyde dehydrogenase 1
family, member B1 protein.
Length = 517
Score = 515 bits (1270), Expect = e-145
Identities = 251/484 (51%), Positives = 320/484 (66%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I Y +LFI+NEW DA +TF T +P G VI VA+G F+ S
Sbjct: 32 PDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
WR DAS+RG+LL ADL+ERD YLA LE+ DNG ++ + L + RY
Sbjct: 92 PWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP DG F +T +PVGVCG I+PWN P++M K+ ALA G TVV+K A
Sbjct: 152 WADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPL+ KEAG P GVVNI+ G+G AG A+ H DV K++FTGS EVG LIQ
Sbjct: 212 EQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
KAAG +NLKRVTLELGGKSP I++ DAD+ A+ +FF+ GQ C A SR +V+ I
Sbjct: 272 KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y++F++ VE AK +VGNPF+ T GPQ+D+ +VLG I+ G+KEGA LL GGER
Sbjct: 332 YNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++I+PTVF V DDM IAKEEIFGPVQ + KF +EEV++RANNT YGLAA +FT
Sbjct: 392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A+ F++ ++AGTVWVN Y + PFGGFK+SG GRE G ++AY E KTV I
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>M63967-1|AAA96830.1| 517|Homo sapiens aldehyde dehydrogenase
protein.
Length = 517
Score = 512 bits (1263), Expect = e-144
Identities = 250/484 (51%), Positives = 319/484 (65%), Gaps = 1/484 (0%)
Query: 3 PEIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNS 62
P+I Y +LFI+NEW DA +TF T +P G VI VA+G F+ S
Sbjct: 32 PDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGS 91
Query: 63 EWRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGS 121
WR DAS+RG+LL ADL+ERD YLA LE+ DNG ++ + L + RY
Sbjct: 92 PWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAG 151
Query: 122 LADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPA 181
ADK G TIP G F +T +PVGVCG I+PWN P++M K+ ALA G TVV+K A
Sbjct: 152 WADKWHGKTIPMHGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVA 211
Query: 182 EQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQ 241
EQTPL+ KEAG P GVVNI+ G+G AG A+ H DV K++FTGS EVG LIQ
Sbjct: 212 EQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHMDVDKVAFTGSTEVGHLIQ 271
Query: 242 KAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGI 301
KAAG +NLKRVTLELGGKSP I++ DAD+ A+ +FF+ GQ C A SR +V+ I
Sbjct: 272 KAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESI 331
Query: 302 YDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERI 361
Y++F++ VE AK +VGNPF+ T GPQ+D+ +VLG I+ G+KEGA LL GGER
Sbjct: 332 YNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
Query: 362 GTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTT 421
G G++I+PTVF V DDM IAKEEIFGPVQ + KF +EEV++RANNT YGLAA +FT
Sbjct: 392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTR 451
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
+L+ A+ F++ ++AGTVWVN Y + PFGGFK+SG GRE G ++AY E KTV I
Sbjct: 452 DLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIK 511
Query: 482 LPKK 485
+P+K
Sbjct: 512 VPQK 515
>AB015228-1|BAA34787.1| 422|Homo sapiens RALDH2-T protein.
Length = 422
Score = 479 bits (1181), Expect = e-135
Identities = 230/419 (54%), Positives = 298/419 (71%), Gaps = 1/419 (0%)
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKI 126
DAS+RG+LL K ADL+ERD LA +ES + G + + L G+ + RY ADKI
Sbjct: 2 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 61
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G TIP DGD F++T +P+GVCG I+PWN P+LMF K+ AL G TVV+KPAEQTPL
Sbjct: 62 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 121
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ KEAG P GV+NI+PG+G AG A+ H + KI+FTGS EVGKLIQ+AAG
Sbjct: 122 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 181
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+NLKRVTLELGGKSP II DADL+ A+ A GVFF+QGQ C A SR++V+ IY++FV
Sbjct: 182 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 241
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ +VE AK VG+PFD +T GPQID+ NK+L LI++G EGA L GG+ +G G+
Sbjct: 242 RRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 301
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+I+PTVF++V DDM IAKEEIFGPVQ IL+F T++EVI+RANN+++GL A +FT ++N A
Sbjct: 302 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 361
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
L S ++AGTVW+N Y + Q+PFGGFK SG GRE G + Y E KTV + +P+K
Sbjct: 362 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQK 420
>AB015227-1|BAA34786.1| 422|Homo sapiens RALDH2-T protein.
Length = 422
Score = 479 bits (1181), Expect = e-135
Identities = 230/419 (54%), Positives = 298/419 (71%), Gaps = 1/419 (0%)
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSLADKI 126
DAS+RG+LL K ADL+ERD LA +ES + G + + L G+ + RY ADKI
Sbjct: 2 DASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGWADKI 61
Query: 127 QGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
G TIP DGD F++T +P+GVCG I+PWN P+LMF K+ AL G TVV+KPAEQTPL
Sbjct: 62 HGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPL 121
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
+ KEAG P GV+NI+PG+G AG A+ H + KI+FTGS EVGKLIQ+AAG
Sbjct: 122 SALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGR 181
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+NLKRVTLELGGKSP II DADL+ A+ A GVFF+QGQ C A SR++V+ IY++FV
Sbjct: 182 SNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFV 241
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ +VE AK VG+PFD +T GPQID+ NK+L LI++G EGA L GG+ +G G+
Sbjct: 242 RRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLECGGKGLGRKGF 301
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
+I+PTVF++V DDM IAKEEIFGPVQ IL+F T++EVI+RANN+++GL A +FT ++N A
Sbjct: 302 FIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKA 361
Query: 427 LQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
L S ++AGTVW+N Y + Q+PFGGFK SG GRE G + Y E KTV + +P+K
Sbjct: 362 LTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVKIPQK 420
>M26760-1|AAA51694.1| 399|Homo sapiens aldehyde dehydrogenase II
protein.
Length = 399
Score = 452 bits (1115), Expect = e-127
Identities = 227/397 (57%), Positives = 275/397 (69%), Gaps = 1/397 (0%)
Query: 90 LAKLESYDNGMVYK-NCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGV 148
LA LE+ DNG Y + L L + +RY ADK G TIP DGD FSYT +PVGV
Sbjct: 1 LAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGV 60
Query: 149 CGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIV 208
CG I+PWN P+LM K+ ALA G VV+K AEQTPLT KEAG P GVVNIV
Sbjct: 61 CGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIV 120
Query: 209 PGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDA 268
PGFG AG A+ H DV K++FTGS E+G++IQ AAG++NLKRVTLELGGKSP IIM+DA
Sbjct: 121 PGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDA 180
Query: 269 DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVN 328
D++ A+ A +FF+QGQ C A SR +VQ IYD+FV +V AK+ VGNPFD T
Sbjct: 181 DMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQ 240
Query: 329 GPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIF 388
GPQ+DE+ K+LG I TGK+EGA LL GG GY+IQPTVF DV D MTIAKEEIF
Sbjct: 241 GPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIF 300
Query: 389 GPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAH 448
GPV ILKF T+EEV+ RANN+ YGLAA +FT +L+ A S+ ++AGTVWVN Y
Sbjct: 301 GPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGA 360
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
Q+PFGG+K SG GRE G ++AY E KTV + +P+K
Sbjct: 361 QSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQK 397
>K03001-1|AAB59500.1| 399|Homo sapiens ALDH2 protein.
Length = 399
Score = 452 bits (1115), Expect = e-127
Identities = 227/397 (57%), Positives = 275/397 (69%), Gaps = 1/397 (0%)
Query: 90 LAKLESYDNGMVYK-NCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGV 148
LA LE+ DNG Y + L L + +RY ADK G TIP DGD FSYT +PVGV
Sbjct: 1 LAALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGV 60
Query: 149 CGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIV 208
CG I+PWN P+LM K+ ALA G VV+K AEQTPLT KEAG P GVVNIV
Sbjct: 61 CGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIV 120
Query: 209 PGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDA 268
PGFG AG A+ H DV K++FTGS E+G++IQ AAG++NLKRVTLELGGKSP IIM+DA
Sbjct: 121 PGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDA 180
Query: 269 DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVN 328
D++ A+ A +FF+QGQ C A SR +VQ IYD+FV +V AK+ VGNPFD T
Sbjct: 181 DMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVVRSVARAKSRVVGNPFDSKTEQ 240
Query: 329 GPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIF 388
GPQ+DE+ K+LG I TGK+EGA LL GG GY+IQPTVF DV D MTIAKEEIF
Sbjct: 241 GPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIF 300
Query: 389 GPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAH 448
GPV ILKF T+EEV+ RANN+ YGLAA +FT +L+ A S+ ++AGTVWVN Y
Sbjct: 301 GPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGA 360
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
Q+PFGG+K SG GRE G ++AY E KTV + +P+K
Sbjct: 361 QSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQK 397
>BC103934-1|AAI03935.1| 923|Homo sapiens aldehyde dehydrogenase 1
family, member L2 protein.
Length = 923
Score = 438 bits (1078), Expect = e-122
Identities = 213/477 (44%), Positives = 306/477 (64%), Gaps = 8/477 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ ++ DA DG+T+DT +P DGS I KV+ F+ N EW +A
Sbjct: 446 FINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFE-NGEWGRMNAR 504
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQGD 129
+RG+L+Y+ ADL+E + E LA +E+ D+G VY L+ G+ + RY DKIQG
Sbjct: 505 ERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGS 564
Query: 130 TIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
TIP + + ++T K+P+GVC +I+PWN P++M K LAAG T+V+KPA+ TP
Sbjct: 565 TIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTP 624
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AG PKGV+NI+PG G AG L+ HPD+ K+ FTGS +GK I K+
Sbjct: 625 LTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCA 684
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLK+V+LELGGKSPLII ND +L+ + VFF++G+ C+AA RL+V+ I+D+F
Sbjct: 685 VSNLKKVSLELGGKSPLIIFNDCELDKTVRMGMGAVFFNKGENCIAAGRLFVEESIHDEF 744
Query: 306 VKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAG 365
V VE K +++G+P D ST +GPQ ++ + K+L ETG KEGA L+ GG ++ G
Sbjct: 745 VTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPG 804
Query: 366 YYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDT--LEEVIDRANNTNYGLAAGIFTTNL 423
++++PTVF DV D M +AKEE FGP+ I KF ++ V+ RAN+T YGLA+G+FT ++
Sbjct: 805 FFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDI 864
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
N A+ S+ +EAGTV++N Y APFGG K SG G++ G +A+ YL+ KTV +
Sbjct: 865 NKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTL 921
>AK222694-1|BAD96414.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 433 bits (1068), Expect = e-121
Identities = 222/477 (46%), Positives = 299/477 (62%), Gaps = 8/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 423 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIS 481
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 482 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 541
Query: 128 GDTIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G TIP + + + T K+PVGVCG+I+PWN P++M K LAAG TVV+KPA+
Sbjct: 542 GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 601
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT +AGIPKGVVN++PG G G L+ HPDV KI FTGS EVGK I K+
Sbjct: 602 TPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+N+K+V+LELGGKSPLII D DLN A+ S VFF++G+ C+AA RL+V+ I+D
Sbjct: 662 CAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHD 721
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PTVF DV D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT
Sbjct: 782 PGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTR 841
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL S ++AGTV+VN Y APFGGFK SG G++ G A+ YL KTV
Sbjct: 842 DINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>AK222535-1|BAD96255.1| 902|Homo sapiens formyltetrahydrofolate
dehydrogenase isoform a variant protein.
Length = 902
Score = 433 bits (1066), Expect = e-121
Identities = 222/477 (46%), Positives = 299/477 (62%), Gaps = 8/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 423 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIG 481
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 482 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 541
Query: 128 GDTIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G TIP + + + T K+PVGVCG+I+PWN P++M K LAAG TVV+KPA+
Sbjct: 542 GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 601
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT +AGIPKGVVN++PG G G L+ HPDV KI FTGS EVGK I K+
Sbjct: 602 TPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+N+K+V+LELGGKSPLII D DLN A+ S VFF++G+ C+AA RL+V+ I+D
Sbjct: 662 CAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHD 721
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PTVF DV D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT
Sbjct: 782 PGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTR 841
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL S ++AGTV+VN Y APFGGFK SG G++ G A+ YL KTV
Sbjct: 842 DVNKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>AB209299-1|BAD92536.1| 954|Homo sapiens aldehyde dehydrogenase 1
family, member L1 variant protein.
Length = 954
Score = 431 bits (1061), Expect = e-120
Identities = 221/477 (46%), Positives = 298/477 (62%), Gaps = 8/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 475 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIS 533
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 534 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 593
Query: 128 GDTIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G TIP + + + T K+PVGVCG+I+PWN P++M K LAAG TVV+KPA+
Sbjct: 594 GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 653
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT +AGIPKGVVN++PG G G L+ HPDV KI FTGS EVGK I K+
Sbjct: 654 TPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 713
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+N+K+V+LELGGKSPLII D DLN A+ S VFF++G+ C+AA RL+V+ I+D
Sbjct: 714 CAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHD 773
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++
Sbjct: 774 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 833
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PTVF V D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT
Sbjct: 834 PGFFFEPTVFTGVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTR 893
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL S ++AGTV+VN Y APFGGFK SG G++ G A+ YL KTV
Sbjct: 894 DINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 950
>AF052732-1|AAC35000.1| 902|Homo sapiens 10-formyltetrahydrofolate
dehydrogenase protein.
Length = 902
Score = 429 bits (1058), Expect = e-120
Identities = 220/477 (46%), Positives = 297/477 (62%), Gaps = 8/477 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 423 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKGAFE-NGRWGKIS 481
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 482 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 541
Query: 128 GDTIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
G TIP + + + T K+PVGVCG+I+PWN P++M K LAAG TVV+KPA+
Sbjct: 542 GSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 601
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TPLT +AGIPKGVVN++PG G G L+ HPDV KI FTGS EVGK I K+
Sbjct: 602 TPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 661
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+N+K+V+LELGG+SP II D DLN A+ S VFF +G+ C+AA RL+V+ I+D
Sbjct: 662 CAISNVKKVSLELGGESPFIIFADCDLNKAVQMGMSSVFFSKGENCIAAGRLFVEDSIHD 721
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++
Sbjct: 722 EFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPR 781
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTT 421
G++ +PTVF DV D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT
Sbjct: 782 PGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTR 841
Query: 422 NLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
++N AL S ++AGTV+VN Y APFGGFK SG G++ G A+ YL KTV
Sbjct: 842 DINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTV 898
>M26761-1|AAA35518.1| 340|Homo sapiens aldehyde dehydrogenase I
protein.
Length = 340
Score = 409 bits (1007), Expect = e-113
Identities = 192/338 (56%), Positives = 248/338 (73%)
Query: 148 VCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNI 207
+CG I+PWN P++M + K+ AL+ G TVVVKPAEQTPLT KEAG P GVVNI
Sbjct: 1 ICGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNI 60
Query: 208 VPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMND 267
VPG+G AG A++ H D+ K++FTGS EVGKLI++AAG +NLKRVTLELGGKSP I++ D
Sbjct: 61 VPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLAD 120
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTV 327
ADL+ A+ +A GVF+HQGQ C+AASR++V+ IYD+FV+ +VE AK +GNP
Sbjct: 121 ADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVT 180
Query: 328 NGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEI 387
GPQID+ +K+L LIE+GKKEGA L GG G GY++QPTVF++V D+M IAKEEI
Sbjct: 181 QGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEI 240
Query: 388 FGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMA 447
FGPVQ I+KF +L++VI RANNT YGL+AG+FT +++ A+ S ++AGTVWVN Y ++
Sbjct: 241 FGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVS 300
Query: 448 HQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
Q PFGGFK SG GRE G Y E KTV + + +K
Sbjct: 301 AQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQK 338
>K03000-1|AAA51695.1| 340|Homo sapiens ALDH1 protein.
Length = 340
Score = 409 bits (1007), Expect = e-113
Identities = 192/338 (56%), Positives = 248/338 (73%)
Query: 148 VCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNI 207
+CG I+PWN P++M + K+ AL+ G TVVVKPAEQTPLT KEAG P GVVNI
Sbjct: 1 ICGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNI 60
Query: 208 VPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMND 267
VPG+G AG A++ H D+ K++FTGS EVGKLI++AAG +NLKRVTLELGGKSP I++ D
Sbjct: 61 VPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLAD 120
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTV 327
ADL+ A+ +A GVF+HQGQ C+AASR++V+ IYD+FV+ +VE AK +GNP
Sbjct: 121 ADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVT 180
Query: 328 NGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEI 387
GPQID+ +K+L LIE+GKKEGA L GG G GY++QPTVF++V D+M IAKEEI
Sbjct: 181 QGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEI 240
Query: 388 FGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMA 447
FGPVQ I+KF +L++VI RANNT YGL+AG+FT +++ A+ S ++AGTVWVN Y ++
Sbjct: 241 FGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVS 300
Query: 448 HQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
Q PFGGFK SG GRE G Y E KTV + + +K
Sbjct: 301 AQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQK 338
>BX538027-1|CAD97973.1| 416|Homo sapiens hypothetical protein
protein.
Length = 416
Score = 350 bits (861), Expect = 6e-96
Identities = 169/288 (58%), Positives = 213/288 (73%)
Query: 198 AGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELG 257
AG P GVVNIVPGFG G A++ HP + KI+FTGS EVGKL+++AA +NLKRVTLELG
Sbjct: 127 AGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELG 186
Query: 258 GKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIR 317
GK+P I+ DADL+LA+ A GVFF+QGQ C AASR++V+ +Y +FV+ +VEYAK
Sbjct: 187 GKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRP 246
Query: 318 VGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVN 377
VG+PFD T GPQID+ +K+L LIE+GKKEGA L GG + G +I+PTVF++V
Sbjct: 247 VGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVT 306
Query: 378 DDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGT 437
D+M IAKEEIFGPVQ ILKF ++EEVI RAN+T+YGL A +FT NL+ AL+ + +E+GT
Sbjct: 307 DNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGT 366
Query: 438 VWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
VW+N Y + QAPFGGFK SG GRE G A+ Y E KTV I L K
Sbjct: 367 VWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDK 414
Score = 78.2 bits (184), Expect = 6e-14
Identities = 37/88 (42%), Positives = 51/88 (57%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
E+K+TK+FI+NEW ++K G+ F T +P I +V +G FQR S
Sbjct: 39 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 98
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLA 91
WR DA RG+LL++ ADL+ERD LA
Sbjct: 99 WRRLDALSRGRLLHQLADLVERDRATLA 126
>AB209821-1|BAD93058.1| 330|Homo sapiens aldehyde dehydrogenase 1A1
variant protein.
Length = 330
Score = 327 bits (804), Expect = 5e-89
Identities = 157/294 (53%), Positives = 203/294 (69%), Gaps = 1/294 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 31 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 90
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 91 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 150
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 151 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 210
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQK 242
QTPLT KEAG P GVVNIVPG+G AG A++ H D+ K++FTGS EVGKLI++
Sbjct: 211 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKE 270
Query: 243 AAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLY 296
AAG +NLKRVTLELGGKSP I++ DADL+ A+ +A GVF+HQGQ C+AASR++
Sbjct: 271 AAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIF 324
>X75425-1|CAA53176.1| 462|Homo sapiens aldehyde dehydrogenase
(NAD+) protein.
Length = 462
Score = 319 bits (783), Expect = 2e-86
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + S+ Y LA
Sbjct: 33 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQSLEYYAGLA 92
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K AL G +V KP+
Sbjct: 93 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALRCGNAMVFKPSPF 152
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 153 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 211
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 212 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 270
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 271 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 330
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 331 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 390
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 391 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 450
Query: 478 VIISL 482
V + +
Sbjct: 451 VCVEM 455
>U50203-1|AAB06721.1| 466|Homo sapiens aldehyde dehydrogenase E3'
protein.
Length = 466
Score = 319 bits (783), Expect = 2e-86
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 37 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 96
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 97 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 156
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 157 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 215
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 216 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 274
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 275 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 334
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 335 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 394
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 395 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 454
Query: 478 VIISL 482
V + +
Sbjct: 455 VCVEM 459
>U34252-1|AAB18827.1| 493|Homo sapiens gamma-aminobutyraldehyde
dehydrogenase protein.
Length = 493
Score = 319 bits (783), Expect = 2e-86
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 64 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 123
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 124 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 183
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 184 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 242
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 243 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 301
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 302 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 361
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 362 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 421
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 422 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 481
Query: 478 VIISL 482
V + +
Sbjct: 482 VCVEM 486
>AL451074-5|CAH74061.1| 518|Homo sapiens aldehyde dehydrogenase 9
family, member A1 protein.
Length = 518
Score = 319 bits (783), Expect = 2e-86
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 89 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 148
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 149 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 208
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 209 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 267
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 268 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 326
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 327 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 386
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 387 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 446
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 447 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 506
Query: 478 VIISL 482
V + +
Sbjct: 507 VCVEM 511
>AF172093-1|AAF43600.1| 494|Homo sapiens
4-trimethylaminobutyraldehyde dehydrogenase protein.
Length = 494
Score = 319 bits (783), Expect = 2e-86
Identities = 170/425 (40%), Positives = 242/425 (56%), Gaps = 8/425 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 65 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 124
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 125 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 184
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 185 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 243
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
+ +K VTLELGGKSPLII +D D+N A+ A F QGQ+C +R++VQ I D
Sbjct: 244 SA-KGIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILD 302
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
KF + V+ + I++G+P E T GP I+ + +VLG ++ K++GA +L GG+
Sbjct: 303 KFTEEVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVP 362
Query: 364 A------GYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
GYY++P V + DDMT KEEIFGPV SIL FDT EV++RAN+T +GLAAG
Sbjct: 363 EDPKLKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAG 422
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
+FT ++ A + ++AGT ++NNY + PFGG+K SG GRENG +E Y + KT
Sbjct: 423 VFTRDIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKT 482
Query: 478 VIISL 482
V + +
Sbjct: 483 VCVEM 487
>BC030589-1|AAH30589.1| 480|Homo sapiens aldehyde dehydrogenase 1
family, member A2 protein.
Length = 480
Score = 303 bits (744), Expect = 8e-82
Identities = 144/251 (57%), Positives = 188/251 (74%)
Query: 235 EVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASR 294
EVGKLIQ+AAG +NLKRVTLELGGKSP II DADL+ A+ A GVFF+QGQ C A SR
Sbjct: 228 EVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSR 287
Query: 295 LYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANL 354
++V+ IY++FV+ +VE AK VG+PFD +T GPQID+ NK+L LI++G EGA L
Sbjct: 288 IFVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL 347
Query: 355 LAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGL 414
GG+ +G G++I+PTVF++V DDM IAKEEIFGPVQ IL+F T++EVI+RANN+++GL
Sbjct: 348 ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGL 407
Query: 415 AAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLE 474
A +FT ++N AL S ++AGTVW+N Y + Q+PFGGFK SG GRE G + Y E
Sbjct: 408 VAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSE 467
Query: 475 EKTVIISLPKK 485
KTV + +P+K
Sbjct: 468 VKTVTVKIPQK 478
Score = 181 bits (441), Expect = 4e-45
Identities = 87/197 (44%), Positives = 115/197 (58%), Gaps = 1/197 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
EIKYTK+FI+NEW +++ G F ++P G + +V + F S
Sbjct: 34 EIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARLAFSLGSV 93
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRI-LSGIPDSVRYLGSL 122
WR DAS+RG+LL K ADL+ERD LA +ES + G + + L G+ + RY
Sbjct: 94 WRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKTFRYYAGW 153
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKI G TIP DGD F++T +P+GVCG I+PWN P+LMF K+ AL G TVV+KPAE
Sbjct: 154 ADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAE 213
Query: 183 QTPLTXXXXXXXXKEAG 199
QTPL+ KE G
Sbjct: 214 QTPLSALYMGALIKEVG 230
>M54931-1|AAA62825.1| 287|Homo sapiens aldehyde dehydrogenase I
protein.
Length = 287
Score = 294 bits (722), Expect = 4e-79
Identities = 150/282 (53%), Positives = 181/282 (64%)
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP T KEAG P GVVNIVPGFG AG A+ H DV K++FTGS E+G++IQ A
Sbjct: 1 TPSTRLYVANLIKEAGFPPGVVNIVPGFGPTAGPAIASHEDVDKVAFTGSTEIGRVIQVA 60
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
AG++NLKRVTLELGGKSP IIM+DAD++ A+ A +FF+QGQ C A SR +VQ IYD
Sbjct: 61 AGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYD 120
Query: 304 KFVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGT 363
+FV +V AK+ VGNPFD T GPQ+DE+ K+LG I TGK+EGA LL GG
Sbjct: 121 EFVVRSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAAD 180
Query: 364 AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNL 423
GY+IQPTVF DV D MTIAKEEIFGPV IL+ + + A +F +
Sbjct: 181 RGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILEVQDHRGGCWESQQFHVRAGAAVFAQRI 240
Query: 424 NNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENG 465
+AGTVWVN Y Q+PFGG+K SG GRE G
Sbjct: 241 WTRPITCPSPQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELG 282
>Y11192-1|CAA72076.1| 535|Homo sapiens succinic semialdehyde
dehydrogenase precursor protein.
Length = 535
Score = 294 bits (721), Expect = 5e-79
Identities = 172/476 (36%), Positives = 252/476 (52%), Gaps = 11/476 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T F+ W+ A TF P G+ + VA F R WR
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 115
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R LL K+ +L+ ++ + LA++ + ++G K + + + A ++
Sbjct: 116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVY 175
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD I T D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP
Sbjct: 176 GDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPF 235
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGKLIQKA 243
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK++
Sbjct: 236 SALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHH 295
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ GI+D
Sbjct: 296 AA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 304 KFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
FVK E K +RVGN F+E T GP I+E + KV + +GA ++ GG+R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQ 414
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA ++ +
Sbjct: 415 LGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQD 474
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 475 PAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>BC113862-1|AAI13863.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 294 bits (721), Expect = 5e-79
Identities = 173/481 (35%), Positives = 252/481 (52%), Gaps = 19/481 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ K+++LELGGK+P II DA+L+ IP F +QG+IC+ SR++VQ IY +F+
Sbjct: 246 H-CKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFL 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG--ERIGT- 363
K VE + +VG P D G I ++ + KV ++ EGA + G +++
Sbjct: 305 KRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 364 ----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AGY++ PTV D+ D+ EEIFGPV ++ FD+ EEVI+RANN YGLAA ++
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++N+ + +K +++G VW N +L PFGG K SGIGRE + + + E KT+
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 480 I 480
+
Sbjct: 485 V 485
>BC034321-1|AAH34321.1| 535|Homo sapiens aldehyde dehydrogenase 5
family, member A1 (succinate-semialdehyde dehydrogenas
protein.
Length = 535
Score = 294 bits (721), Expect = 5e-79
Identities = 172/476 (36%), Positives = 252/476 (52%), Gaps = 11/476 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T F+ W+ A TF P G+ + VA F R WR
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 115
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R LL K+ +L+ ++ + LA++ + ++G K + + + A ++
Sbjct: 116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVY 175
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD I T D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP
Sbjct: 176 GDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPF 235
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGKLIQKA 243
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK++
Sbjct: 236 SALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHH 295
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ GI+D
Sbjct: 296 AA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 304 KFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
FVK E K +RVGN F+E T GP I+E + KV + +GA ++ GG+R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQ 414
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA ++ +
Sbjct: 415 LGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQD 474
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 475 PAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>AL445190-1|CAI95158.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 294 bits (721), Expect = 5e-79
Identities = 173/481 (35%), Positives = 252/481 (52%), Gaps = 19/481 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ K+++LELGGK+P II DA+L+ IP F +QG+IC+ SR++VQ IY +F+
Sbjct: 246 H-CKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFL 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG--ERIGT- 363
K VE + +VG P D G I ++ + KV ++ EGA + G +++
Sbjct: 305 KRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 364 ----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AGY++ PTV D+ D+ EEIFGPV ++ FD+ EEVI+RANN YGLAA ++
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++N+ + +K +++G VW N +L PFGG K SGIGRE + + + E KT+
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 480 I 480
+
Sbjct: 485 V 485
>AL031230-4|CAA20248.1| 535|Homo sapiens aldehyde dehydrogenase 5
family, member A1 (succinate-semialdehyde dehydrogenas
protein.
Length = 535
Score = 294 bits (721), Expect = 5e-79
Identities = 172/476 (36%), Positives = 252/476 (52%), Gaps = 11/476 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T F+ W+ A TF P G+ + VA F R WR
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 115
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R LL K+ +L+ ++ + LA++ + ++G K + + + A ++
Sbjct: 116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVY 175
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD I T D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP
Sbjct: 176 GDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPF 235
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGKLIQKA 243
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK++
Sbjct: 236 SALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHH 295
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ GI+D
Sbjct: 296 AA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 304 KFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
FVK E K +RVGN F+E T GP I+E + KV + +GA ++ GG+R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQ 414
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA ++ +
Sbjct: 415 LGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQD 474
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 475 PAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>AL021939-1|CAI20305.1| 487|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 487
Score = 294 bits (721), Expect = 5e-79
Identities = 173/481 (35%), Positives = 252/481 (52%), Gaps = 19/481 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ K+++LELGGK+P II DA+L+ IP F +QG+IC+ SR++VQ IY +F+
Sbjct: 246 H-CKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFL 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG--ERIGT- 363
K VE + +VG P D G I ++ + KV ++ EGA + G +++
Sbjct: 305 KRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 364 ----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AGY++ PTV D+ D+ EEIFGPV ++ FD+ EEVI+RANN YGLAA ++
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++N+ + +K +++G VW N +L PFGG K SGIGRE + + + E KT+
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 480 I 480
+
Sbjct: 485 V 485
>AJ427355-1|CAD20884.1| 535|Homo sapiens succinic semialdehyde
dehydrogenase precursor protein.
Length = 535
Score = 294 bits (721), Expect = 5e-79
Identities = 172/476 (36%), Positives = 252/476 (52%), Gaps = 11/476 (2%)
Query: 8 TKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLA 67
T F+ W+ A TF P G+ + VA F R WR
Sbjct: 61 TDSFVGGRWLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREV 115
Query: 68 DASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQ 127
A +R LL K+ +L+ ++ + LA++ + ++G K + + + A ++
Sbjct: 116 SAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVY 175
Query: 128 GDTIPTDG-DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
GD I T D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP
Sbjct: 176 GDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPF 235
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGKLIQKA 243
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK++
Sbjct: 236 SALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHH 295
Query: 244 AGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYD 303
A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ GI+D
Sbjct: 296 AA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHD 354
Query: 304 KFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIG 362
FVK E K +RVGN F+E T GP I+E + KV + +GA ++ GG+R
Sbjct: 355 AFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQ 414
Query: 363 TAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTN 422
+ +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA ++ +
Sbjct: 415 LGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQD 474
Query: 423 LNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTV 478
+ ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K V
Sbjct: 475 PAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYV 530
>AF303134-1|AAG42417.1| 487|Homo sapiens aldehyde dehydrogenase 12
protein.
Length = 487
Score = 294 bits (721), Expect = 5e-79
Identities = 173/481 (35%), Positives = 252/481 (52%), Gaps = 19/481 (3%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+ K+++LELGGK+P II DA+L+ IP F +QG+IC+ SR++VQ IY +F+
Sbjct: 246 H-CKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQGEICLCTSRIFVQKSIYSEFL 304
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGG--ERIGT- 363
K VE + +VG P D G I ++ + KV ++ EGA + G +++
Sbjct: 305 KRFVEATRKWKVGIPSDPLVSIGALISKAHLEKVRSYVKRALAEGAQIWCGEGVDKLSLP 364
Query: 364 ----AGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIF 419
AGY++ PTV D+ D+ EEIFGPV ++ FD+ EEVI+RANN YGLAA ++
Sbjct: 365 ARNQAGYFMLPTVITDIKDESCCMTEEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVW 424
Query: 420 TTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVI 479
++N+ + +K +++G VW N +L PFGG K SGIGRE + + + E KT+
Sbjct: 425 SSNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTIT 484
Query: 480 I 480
+
Sbjct: 485 V 485
>AK095827-1|BAC04634.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ38508 fis, clone HCHON2000322, moderately
similar to 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (EC
1.5.1.6). ).
Length = 752
Score = 279 bits (683), Expect = 2e-74
Identities = 136/306 (44%), Positives = 192/306 (62%), Gaps = 6/306 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ ++ DA DG+T+DT +P DGS I KV+ F+ N EW +A
Sbjct: 446 FINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFE-NGEWGRMNAR 504
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQGD 129
+RG+L+Y+ ADL+E + E LA +E+ D+G VY L+ G+ + RY DKIQG
Sbjct: 505 ERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGS 564
Query: 130 TIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
TIP + + ++T K+P+GVC +I+PWN P++M K LAAG T+V+KPA+ TP
Sbjct: 565 TIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTP 624
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AG PKGV+NI+PG G AG L+ HPD+ K+ FTGS +GK I K+
Sbjct: 625 LTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCA 684
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLK+V+LELGGKSPLII ND +L+ A+ VFF++G+ C+AA RL+V+ I+D+F
Sbjct: 685 VSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEF 744
Query: 306 VKGAVE 311
V VE
Sbjct: 745 VTRVVE 750
>BC103935-1|AAI03936.1| 488|Homo sapiens ALDH1L2 protein protein.
Length = 488
Score = 276 bits (677), Expect = 1e-73
Identities = 134/301 (44%), Positives = 190/301 (63%), Gaps = 6/301 (1%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FI+ ++ DA DG+T+DT +P DGS I KV+ F+ N EW +A
Sbjct: 184 FINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFE-NGEWGRMNAR 242
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQGD 129
+RG+L+Y+ ADL+E + E LA +E+ D+G VY L+ G+ + RY DKIQG
Sbjct: 243 ERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGS 302
Query: 130 TIPTD----GDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTP 185
TIP + + ++T K+P+GVC +I+PWN P++M K LAAG T+V+KPA+ TP
Sbjct: 303 TIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTP 362
Query: 186 LTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAG 245
LT +AG PKGV+NI+PG G AG L+ HPD+ K+ FTGS +GK I K+
Sbjct: 363 LTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCA 422
Query: 246 TNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKF 305
+NLK+V+LELGGKSPLII ND +L+ A+ VFF++G+ C+AA RL+V+ I+D+F
Sbjct: 423 VSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEF 482
Query: 306 V 306
V
Sbjct: 483 V 483
>AJ427354-1|CAD20883.2| 480|Homo sapiens succinic semialdehyde
dehydrogenase protein.
Length = 480
Score = 274 bits (671), Expect = 6e-73
Identities = 169/481 (35%), Positives = 250/481 (51%), Gaps = 24/481 (4%)
Query: 16 WVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKL 75
W+ A TF P G+ + VA F R WR A +R L
Sbjct: 1 WLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREVSAKERSSL 55
Query: 76 LYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG 135
L K+ +L+ ++ + LA++ + ++G K + + + A ++ GD I T
Sbjct: 56 LRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPA 115
Query: 136 -DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXX 194
D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP +
Sbjct: 116 KDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEV 175
Query: 195 XK-------------EAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGK 238
+ +AGIP GV N++P ++A G A+ P V+KISFTGS GK
Sbjct: 176 NQGFLLDLDPLLLASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGK 235
Query: 239 LIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQ 298
++ A N++KRV++ELGG +P I+ + A+++ A+ A + F + GQ CV +++ VQ
Sbjct: 236 ILLHHAA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQ 294
Query: 299 SGIYDKFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAG 357
GI+D FVK E K +RVG+ F+E T GP I+E + KV + +GA ++ G
Sbjct: 295 RGIHDAFVKAFAEAMKKNLRVGSGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTG 354
Query: 358 GERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAG 417
G+R + +PT+ +V DM EE FGP+ ++KFDT EE I AN + GLA
Sbjct: 355 GKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGY 414
Query: 418 IFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
++ + + ++ +E G V VN L + + PFGG K SG+GRE ++ YLE K
Sbjct: 415 FYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKY 474
Query: 478 V 478
V
Sbjct: 475 V 475
>L34820-1|AAA67057.1| 323|Homo sapiens succinate semialdehyde
dehydrogenase protein.
Length = 323
Score = 239 bits (586), Expect = 1e-62
Identities = 130/318 (40%), Positives = 186/318 (58%), Gaps = 5/318 (1%)
Query: 165 KVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDA---GVALTH 221
KV ALAAGCTVVVKPAE TP + +AGIP GV N++P ++A G A+
Sbjct: 2 KVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICT 61
Query: 222 HPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGV 281
P V+KISFTGS GK++ A N++KRV++ELGG +P I+ + A+++ A+ A +
Sbjct: 62 DPLVSKISFTGSTTTGKILLHHAA-NSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASK 120
Query: 282 FFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKA-IRVGNPFDESTVNGPQIDESMMNKV 340
F + GQ CV +++ VQ GI+D FVK E K +RVGN F+E T GP I+E + KV
Sbjct: 121 FRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKV 180
Query: 341 LGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTL 400
+ +GA ++ GG+R + +PT+ +V DM EE FGP+ ++KFDT
Sbjct: 181 EKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTE 240
Query: 401 EEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGI 460
EE I AN + GLA ++ + + ++ +E G V VN L + + PFGG K SG+
Sbjct: 241 EEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGL 300
Query: 461 GRENGIKAVEAYLEEKTV 478
GRE ++ YLE K V
Sbjct: 301 GREGSKYGIDEYLELKYV 318
>AL591031-3|CAI12260.1| 238|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 238
Score = 225 bits (550), Expect = 3e-58
Identities = 110/222 (49%), Positives = 141/222 (63%), Gaps = 1/222 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPD 224
QTPLT KEAG P GVVNIVPG+G AG A++ H D
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMD 238
>AK124908-1|BAC85992.1| 470|Homo sapiens protein ( Homo sapiens
cDNA FLJ42918 fis, clone BRHIP3027137, highly similar
to 10-formyltetrahydrofolate dehydrogenase (EC 1.5.1.6).
).
Length = 470
Score = 222 bits (543), Expect = 2e-57
Identities = 107/221 (48%), Positives = 150/221 (67%), Gaps = 2/221 (0%)
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFV 306
+N+K+V+LELGGKSPLII D DLN A+ S VFF++G+ C+AA RL+V+ I+D+FV
Sbjct: 200 SNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFV 259
Query: 307 KGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY 366
+ VE + ++VGNP D T +GPQ + + K++ + G KEGA L+ GG ++ G+
Sbjct: 260 RRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGF 319
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKF--DTLEEVIDRANNTNYGLAAGIFTTNLN 424
+ +PTVF DV D M IAKEE FGPV I +F L+ V+ RAN T +GLA+G+FT ++N
Sbjct: 320 FFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDIN 379
Query: 425 NALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENG 465
AL S ++AGTV+VN Y APFGGF+ SG G++ G
Sbjct: 380 KALYVSDKLQAGTVFVNTYNKTDVAAPFGGFEQSGFGKDLG 420
>AL591031-2|CAI12259.1| 230|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 230
Score = 215 bits (524), Expect = 4e-55
Identities = 105/210 (50%), Positives = 134/210 (63%), Gaps = 1/210 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
QTPLT KEAG P GVVNIVPG+G
Sbjct: 197 QTPLTALHVASLIKEAGFPPGVVNIVPGYG 226
>AK223244-1|BAD96964.1| 535|Homo sapiens aldehyde dehydrogenase 6A1
precursor variant protein.
Length = 535
Score = 210 bits (514), Expect = 6e-54
Identities = 148/481 (30%), Positives = 236/481 (49%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNARDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+EVI NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEVIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>BC032371-1|AAH32371.1| 535|Homo sapiens aldehyde dehydrogenase 6
family, member A1 protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>BC004909-1|AAH04909.1| 535|Homo sapiens aldehyde dehydrogenase 6
family, member A1 protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>AJ249994-1|CAB76468.1| 535|Homo sapiens methylmalonate
semialdehyde dehydrogenase protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>AF159889-1|AAF80380.1| 535|Homo sapiens methylmalonate
semialdehyde dehydrogenase protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>AF148855-1|AAG29581.1| 535|Homo sapiens
methylmalonate-semialdehyde dehydrogenase protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>AF148505-1|AAF04489.1| 535|Homo sapiens
methylmalonate-semialdehyde dehydrogenase protein.
Length = 535
Score = 209 bits (510), Expect = 2e-53
Identities = 147/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ VE+AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>AK222687-1|BAD96407.1| 535|Homo sapiens aldehyde dehydrogenase 6A1
precursor variant protein.
Length = 535
Score = 208 bits (507), Expect = 4e-53
Identities = 146/481 (30%), Positives = 235/481 (48%), Gaps = 20/481 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
KLFI ++V++K + D +P VI +V + F W
Sbjct: 41 KLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPA---WADTS 97
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQ 127
R ++L ++ LI+ + + +AKL + + G + + G+ V + S+ +
Sbjct: 98 VLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMM 156
Query: 128 GDTIPT---DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQT 184
G+T+P+ D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+
Sbjct: 157 GETMPSITKDMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERV 214
Query: 185 PLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAA 244
P +++G P G +NI+ G E + HPD+ ISF GS + G+ I +
Sbjct: 215 PGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER- 272
Query: 245 GTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDK 304
G+ + KRV +G K+ ++M DA+ + F GQ C+A S V G K
Sbjct: 273 GSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKK 331
Query: 305 FVKGAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA 364
++ V++AK +RV GP I +V LI++G KEGA++L G +I
Sbjct: 332 WLPELVDHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVK 391
Query: 365 GY----YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFT 420
GY ++ PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFT
Sbjct: 392 GYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFT 451
Query: 421 TNLNNALQFSKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKT 477
TN A +++ V+ G V VN + + F G + S G N G + ++ Y + KT
Sbjct: 452 TNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKT 511
Query: 478 V 478
+
Sbjct: 512 I 512
>BC002515-1|AAH02515.3| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 194 bits (472), Expect = 8e-49
Identities = 134/473 (28%), Positives = 214/473 (45%), Gaps = 13/473 (2%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
GE T+ P + IA+V + ++ W A +RG+++ + D
Sbjct: 35 GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGD 91
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYT 141
+ + L L S + G + + + D Y L+ I G +P++ +
Sbjct: 92 ALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALI 151
Query: 142 LK-QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX----K 196
+ PVG+ G+I +N P+ ++ A+ G + K A T L +
Sbjct: 152 EQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLE 211
Query: 197 EAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLEL 256
+ +P + ++ G G D G A+ V +SFTGS +VGK + R LEL
Sbjct: 212 DNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QERFGRSLLEL 269
Query: 257 GGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAI 316
GG + +I DADL+L +P A GQ C A RL++ I+D+ V + I
Sbjct: 270 GGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQI 329
Query: 317 RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADV 376
RVGNP+D + + GP + ++ LG +E KKEG ++ GG+ + G Y++PT+ +
Sbjct: 330 RVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGL 389
Query: 377 NDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF--SKHVE 434
D +IA E F P+ + KF EEV N GL++ IFT +L ++ K +
Sbjct: 390 GHDASIAHTETFAPILYVFKFQNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSD 449
Query: 435 AGTVWVNNYLTMAH-QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
G V VN + A FGG K +G GRE+G A + Y+ T I+ K L
Sbjct: 450 CGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDL 502
>S74728-1|AAB31966.1| 511|Homo sapiens antiquitin protein.
Length = 511
Score = 193 bits (471), Expect = 1e-48
Identities = 134/473 (28%), Positives = 214/473 (45%), Gaps = 13/473 (2%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
GE T+ P + IA+V + ++ W A +RG+++ + D
Sbjct: 35 GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGD 91
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYT 141
+ + L L S + G + + + D Y L+ I G +P++ +
Sbjct: 92 ALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALI 151
Query: 142 LK-QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX----K 196
+ PVG+ G+I +N P+ ++ A+ G + K A T L +
Sbjct: 152 EQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLE 211
Query: 197 EAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLEL 256
+ +P + ++ G G D G A+ V +SFTGS +VGK + R LEL
Sbjct: 212 DNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QERFGRSLLEL 269
Query: 257 GGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAI 316
GG + +I DADL+L +P A GQ C A RL++ I+D+ V + I
Sbjct: 270 GGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQI 329
Query: 317 RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADV 376
RVGNP+D + + GP + ++ LG +E KKEG ++ GG+ + G Y++PT+ +
Sbjct: 330 RVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGL 389
Query: 377 NDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF--SKHVE 434
D +IA E F P+ + KF EEV N GL++ IFT +L ++ K +
Sbjct: 390 GHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSD 449
Query: 435 AGTVWVNNYLTMAH-QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
G V VN + A FGG K +G GRE+G A + Y+ T I+ K L
Sbjct: 450 CGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDL 502
>BC073174-1|AAH73174.1| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 193 bits (471), Expect = 1e-48
Identities = 134/473 (28%), Positives = 214/473 (45%), Gaps = 13/473 (2%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
GE T+ P + IA+V + ++ W A +RG+++ + D
Sbjct: 35 GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGD 91
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYT 141
+ + L L S + G + + + D Y L+ I G +P++ +
Sbjct: 92 ALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALI 151
Query: 142 LK-QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX----K 196
+ PVG+ G+I +N P+ ++ A+ G + K A T L +
Sbjct: 152 EQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLE 211
Query: 197 EAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLEL 256
+ +P + ++ G G D G A+ V +SFTGS +VGK + R LEL
Sbjct: 212 DNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QERFGRSLLEL 269
Query: 257 GGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAI 316
GG + +I DADL+L +P A GQ C A RL++ I+D+ V + I
Sbjct: 270 GGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQI 329
Query: 317 RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADV 376
RVGNP+D + + GP + ++ LG +E KKEG ++ GG+ + G Y++PT+ +
Sbjct: 330 RVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGL 389
Query: 377 NDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF--SKHVE 434
D +IA E F P+ + KF EEV N GL++ IFT +L ++ K +
Sbjct: 390 GHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSD 449
Query: 435 AGTVWVNNYLTMAH-QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
G V VN + A FGG K +G GRE+G A + Y+ T I+ K L
Sbjct: 450 CGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDL 502
>BC071712-1|AAH71712.1| 511|Homo sapiens aldehyde dehydrogenase 7
family, member A1 protein.
Length = 511
Score = 193 bits (471), Expect = 1e-48
Identities = 134/473 (28%), Positives = 214/473 (45%), Gaps = 13/473 (2%)
Query: 22 GETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFAD 81
GE T+ P + IA+V + ++ W A +RG+++ + D
Sbjct: 35 GEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI---WADIPAPKRGEIVRQIGD 91
Query: 82 LIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYT 141
+ + L L S + G + + + D Y L+ I G +P++ +
Sbjct: 92 ALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDICDYAVGLSRMIGGPILPSERSGHALI 151
Query: 142 LK-QPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXX----K 196
+ PVG+ G+I +N P+ ++ A+ G + K A T L +
Sbjct: 152 EQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVAVTKIIAKVLE 211
Query: 197 EAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLEL 256
+ +P + ++ G G D G A+ V +SFTGS +VGK + R LEL
Sbjct: 212 DNKLPGAICSLTCG-GADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QERFGRSLLEL 269
Query: 257 GGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAI 316
GG + +I DADL+L +P A GQ C A RL++ I+D+ V + I
Sbjct: 270 GGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVNRLKKAYAQI 329
Query: 317 RVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADV 376
RVGNP+D + + GP + ++ LG +E KKEG ++ GG+ + G Y++PT+ +
Sbjct: 330 RVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGL 389
Query: 377 NDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF--SKHVE 434
D +IA E F P+ + KF EEV N GL++ IFT +L ++ K +
Sbjct: 390 GHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSD 449
Query: 435 AGTVWVNNYLTMAH-QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKKL 486
G V VN + A FGG K +G GRE+G A + Y+ T I+ K L
Sbjct: 450 CGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDL 502
>M93405-1|AAA36328.1| 430|Homo sapiens methylmalonate semialdehyde
dehydrogenase protein.
Length = 430
Score = 191 bits (466), Expect = 4e-48
Identities = 132/412 (32%), Positives = 210/412 (50%), Gaps = 17/412 (4%)
Query: 78 KFADLIERDFEYLAKLESYDNGMVYKNCLR-ILSGIPDSVRYLGSLADKIQGDTIPT--- 133
++ LI+ + + +AKL + + G + + G+ V + S+ + G+T+P+
Sbjct: 2 RYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGL-QVVEHACSVTSLMMGETMPSITK 60
Query: 134 DGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXX 193
D D +SY L P+GVC I P+N P ++ L A+ G T ++KP+E+ P
Sbjct: 61 DMDLYSYRL--PLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAK 118
Query: 194 XXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVT 253
+++G P G +NI+ G E + HPD+ ISF GS + G+ I + G+ + KRV
Sbjct: 119 LLQDSGAPDGTLNIIHGQHEAVNF-ICDHPDIKAISFVGSNKAGEYIFER-GSRHGKRVQ 176
Query: 254 LELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYA 313
+G K+ ++M DA+ + F GQ C+A S V G K++ VE+A
Sbjct: 177 ANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTA-VLVGEAKKWLPELVEHA 235
Query: 314 KAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGY----YIQ 369
K +RV GP I +V LI++G KEGA++L G +I GY ++
Sbjct: 236 KNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVG 295
Query: 370 PTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQF 429
PT+ ++V +MT KEEIFGPV +L+ +TL+E I NN YG IFTTN A ++
Sbjct: 296 PTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKY 355
Query: 430 SKHVEAGTVWVNNYLTM-AHQAPFGGFKDSGIGREN--GIKAVEAYLEEKTV 478
+ V+ G V VN + + F G + S G N G + ++ Y + KT+
Sbjct: 356 AHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTI 407
>AL591031-4|CAI12261.1| 203|Homo sapiens aldehyde dehydrogenase 1
family, member A1 protein.
Length = 203
Score = 186 bits (453), Expect = 2e-46
Identities = 91/185 (49%), Positives = 119/185 (64%), Gaps = 1/185 (0%)
Query: 4 EIKYTKLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSE 63
+I+YTK+FI+NEW D+ G+ F F+P + +V +G FQ S
Sbjct: 17 KIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSP 76
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNC-LRILSGIPDSVRYLGSL 122
WR DAS+RG+LLYK ADLIERD LA +ES + G +Y N L L+G ++RY
Sbjct: 77 WRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGW 136
Query: 123 ADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAE 182
ADKIQG TIP DG+ F+YT +P+GVCG I+PWN P++M + K+ AL+ G TVVVKPAE
Sbjct: 137 ADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAE 196
Query: 183 QTPLT 187
QTPLT
Sbjct: 197 QTPLT 201
>AL445190-2|CAI95159.1| 433|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 433
Score = 147 bits (357), Expect = 7e-35
Identities = 97/279 (34%), Positives = 135/279 (48%), Gaps = 12/279 (4%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQ 285
+ K+++LELGGK+P II DA+L+ IP F +Q
Sbjct: 246 -HCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQ 283
Score = 116 bits (279), Expect = 2e-25
Identities = 58/156 (37%), Positives = 90/156 (57%), Gaps = 7/156 (4%)
Query: 332 IDESMMNKVLGLIETGKKEGANLLAGG--ERIGT-----AGYYIQPTVFADVNDDMTIAK 384
+ S N+V ++ EGA + G +++ AGY++ PTV D+ D+
Sbjct: 276 VRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMT 335
Query: 385 EEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYL 444
EEIFGPV ++ FD+ EEVI+RANN YGLAA ++++N+ + +K +++G VW N +L
Sbjct: 336 EEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL 395
Query: 445 TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG K SGIGRE + + + E KT+ +
Sbjct: 396 IRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITV 431
>AL021939-2|CAI20306.1| 433|Homo sapiens aldehyde dehydrogenase 8
family, member A1 protein.
Length = 433
Score = 147 bits (357), Expect = 7e-35
Identities = 97/279 (34%), Positives = 135/279 (48%), Gaps = 12/279 (4%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQ 285
+ K+++LELGGK+P II DA+L+ IP F +Q
Sbjct: 246 -HCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQ 283
Score = 116 bits (279), Expect = 2e-25
Identities = 58/156 (37%), Positives = 90/156 (57%), Gaps = 7/156 (4%)
Query: 332 IDESMMNKVLGLIETGKKEGANLLAGG--ERIGT-----AGYYIQPTVFADVNDDMTIAK 384
+ S N+V ++ EGA + G +++ AGY++ PTV D+ D+
Sbjct: 276 VRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMT 335
Query: 385 EEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYL 444
EEIFGPV ++ FD+ EEVI+RANN YGLAA ++++N+ + +K +++G VW N +L
Sbjct: 336 EEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL 395
Query: 445 TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG K SGIGRE + + + E KT+ +
Sbjct: 396 IRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITV 431
>S61044-1|AAB26658.1| 453|Homo sapiens aldehyde dehydrogenase
isozyme 3 protein.
Length = 453
Score = 146 bits (353), Expect = 2e-34
Identities = 115/392 (29%), Positives = 179/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG +VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>M77477-1|AAB46377.1| 453|Homo sapiens aldehyde dehydrogenase
protein.
Length = 453
Score = 146 bits (353), Expect = 2e-34
Identities = 115/392 (29%), Positives = 179/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG +VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>M74542-1|AAA51696.1| 453|Homo sapiens aldehyde dehydrogenase type
III protein.
Length = 453
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>BT007102-1|AAP35766.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>BC021194-1|AAH21194.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>BC008892-1|AAH08892.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>BC004370-1|AAH04370.1| 453|Homo sapiens aldehyde dehydrogenase 3
family, memberA1 protein.
Length = 453
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 50 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 109
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 110 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 168
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 169 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 225
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 226 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 284
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 285 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 338
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 339 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 398
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 399 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 430
>BC004102-1|AAH04102.1| 512|Homo sapiens ALDH3A1 protein protein.
Length = 512
Score = 145 bits (352), Expect = 3e-34
Identities = 115/392 (29%), Positives = 178/392 (45%), Gaps = 13/392 (3%)
Query: 91 AKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCG 150
A L + Y+ + +L I ++ L A + P Y +P+GV
Sbjct: 109 ADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVL 168
Query: 151 LILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPG 210
+I WN P + + +V A+AAG VV+KP+E + + + K + ++ G
Sbjct: 169 VIGTWNYPFNLTIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVING 227
Query: 211 FGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADL 270
+ L D I +TGS VGK+I AA +L VTLELGGKSP + + DL
Sbjct: 228 GVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNCDL 284
Query: 271 NLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVNGP 330
++A G F + GQ CVA + I ++ V+ + K G +S G
Sbjct: 285 DVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGR 343
Query: 331 QIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGP 390
I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIFGP
Sbjct: 344 IISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGP 397
Query: 391 VQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--MAH 448
V I+ +LEE I N LA +F++N + +G V N+ + H
Sbjct: 398 VLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLH 457
Query: 449 QAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG +SG+G +G K+ E + ++ ++
Sbjct: 458 SLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 489
>AK222848-1|BAD96568.1| 433|Homo sapiens aldehyde dehydrogenase 8A1
isoform 2 variant protein.
Length = 433
Score = 144 bits (350), Expect = 5e-34
Identities = 96/279 (34%), Positives = 134/279 (48%), Gaps = 12/279 (4%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
FID +++ D++ P G V +V F W
Sbjct: 13 FIDGKFLPCSS--YIDSYDPSTGEVYCRVPNSGKDEIEAAVKAAREAFP---SWSSRSPQ 67
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
+R ++L + ADL+E+ E A+ ES D G L IP SV+ A T
Sbjct: 68 ERSRVLNQVADLLEQSLEEFAQAESKDQGKTL--ALARTMDIPRSVQNFRFFASSSLHHT 125
Query: 131 IP-TDGDSFS---YTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPL 186
T D YT++ PVGV GLI PWN+P+ + K+ A+AAG TV+ KP+E T +
Sbjct: 126 SECTQMDHLGCMHYTVRAPVGVAGLISPWNLPLYLLTWKIAPAMAAGNTVIAKPSELTSV 185
Query: 187 TXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGT 246
T +AG+P GVVNIV G G G AL HP+V ISFTGS + I + +
Sbjct: 186 TAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERITQLSAP 245
Query: 247 NNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQ 285
+ K+++ ELGGK+P II DA+L+ IP F +Q
Sbjct: 246 -HCKKLSPELGGKNPAIIFEDANLDECIPATVRSSFANQ 283
Score = 116 bits (279), Expect = 2e-25
Identities = 58/156 (37%), Positives = 90/156 (57%), Gaps = 7/156 (4%)
Query: 332 IDESMMNKVLGLIETGKKEGANLLAGG--ERIGT-----AGYYIQPTVFADVNDDMTIAK 384
+ S N+V ++ EGA + G +++ AGY++ PTV D+ D+
Sbjct: 276 VRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMT 335
Query: 385 EEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYL 444
EEIFGPV ++ FD+ EEVI+RANN YGLAA ++++N+ + +K +++G VW N +L
Sbjct: 336 EEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL 395
Query: 445 TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG K SGIGRE + + + E KT+ +
Sbjct: 396 IRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITV 431
>U75296-1|AAC50966.1| 485|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 485
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>U75295-1|AAC50965.1| 508|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 508
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>U46689-1|AAC51121.1| 485|Homo sapiens aldehyde dehydrogenase
protein.
Length = 485
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>L47162-1|AAB01003.1| 485|Homo sapiens fatty aldehyde dehydrogenase
protein.
Length = 485
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>CR457422-1|CAG33703.1| 485|Homo sapiens ALDH3A2 protein.
Length = 485
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>BC002430-1|AAH02430.1| 508|Homo sapiens aldehyde dehydrogenase 3
family, member A2 protein.
Length = 508
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 95 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 154
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 155 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 210
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 211 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 269
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 270 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 323
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 324 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 383
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 384 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 432
>AB208894-1|BAD92131.1| 461|Homo sapiens aldehyde dehydrogenase 3A2
variant protein.
Length = 461
Score = 136 bits (328), Expect = 2e-31
Identities = 98/349 (28%), Positives = 165/349 (47%), Gaps = 13/349 (3%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
+Y QP+GV +I WN P ++ + ++ A+AAG V++KP+E + T +
Sbjct: 71 AYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY 130
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + + ++ G E+ L D I +TG+ VGK++ +AA +L VTLELGG
Sbjct: 131 -LDQDLYIVINGGVEETTELLKQRFD--HIFYTGNTAVGKIVMEAAA-KHLTPVTLELGG 186
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
KSP I D DL++ G + + GQ C+A + ++ + ++ V E K
Sbjct: 187 KSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEF-Y 245
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G ES I+ ++L L+E G + GGE A YI PTV DV+
Sbjct: 246 GENIKESPDYERIINLRHFKRILSLLE-----GQKIAFGGET-DEATRYIAPTVLTDVDP 299
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ ++E I+ N LA +F+ N + +G V
Sbjct: 300 KTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLIKRMIDETSSGGV 359
Query: 439 WVNNYLT--MAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLPKK 485
N+ + + PFGG SG+G +G + + + ++ ++ K+
Sbjct: 360 TGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLKR 408
>AK222486-1|BAD96206.1| 563|Homo sapiens aldehyde dehydrogenase 4A1
precursor variant protein.
Length = 563
Score = 133 bits (322), Expect = 1e-30
Identities = 115/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALIGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E IRVG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIRVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>U24267-1|AAC50501.1| 563|Homo sapiens pyrroline-5-carboxylate
dehydrogenase protein.
Length = 563
Score = 132 bits (319), Expect = 3e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>U24266-1|AAC50500.1| 563|Homo sapiens pyrroline-5-carboxylate
dehydrogenase protein.
Length = 563
Score = 132 bits (319), Expect = 3e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>BC023600-1|AAH23600.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 132 bits (319), Expect = 3e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>AL954340-2|CAI39493.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 132 bits (319), Expect = 3e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>AL080251-1|CAI23417.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 132 bits (319), Expect = 3e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>BC007581-1|AAH07581.1| 563|Homo sapiens aldehyde dehydrogenase 4
family, member A1 protein.
Length = 563
Score = 132 bits (318), Expect = 4e-30
Identities = 114/447 (25%), Positives = 191/447 (42%), Gaps = 22/447 (4%)
Query: 38 KVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKLLYKFADLIE--RDFEYLAKLES 95
KVAK EW L + R ++ K AD++ R E LAK
Sbjct: 90 KVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMV 149
Query: 96 YDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGD---TIPTDGDSFSYTLKQPVGVCGLI 152
V + + + + D R+ A +++G ++P +S Y + G I
Sbjct: 150 GQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAI 207
Query: 153 LPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFG 212
P+N + N G V+ KP++ L +EAG+P ++ VP G
Sbjct: 208 SPFNFTAIGG-NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADG 266
Query: 213 EDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTN-----NLKRVTLELGGKSPLIIMND 267
G +T + I+FTGS+ K + K N R+ E GGK+ +
Sbjct: 267 PLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRS 326
Query: 268 ADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDE-ST 326
AD+ + F + GQ C A SRLYV ++ + +E I+VG+P ++ T
Sbjct: 327 ADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGT 386
Query: 327 VNGPQIDESMMNKVLGLIETGKKE-GANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKE 385
ID ++ +E + +LAGG+ + GY+++P + + I KE
Sbjct: 387 FFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKE 446
Query: 386 EIFGPVQSILKF--DTLEEVIDRANN-TNYGLAAGIFTTNLNNALQFSKHVE--AGTVWV 440
EIFGPV S+ + D +E + ++ T+YGL +F+ + + + +K + AG ++
Sbjct: 447 EIFGPVLSVYVYPDDKYKETLQLIDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYI 506
Query: 441 NNYLT--MAHQAPFGGFKDSGIGRENG 465
N+ T + Q PFGG + SG + G
Sbjct: 507 NDKSTGSIVGQQPFGGARASGTNDKPG 533
>BT006810-1|AAP35456.1| 385|Homo sapiens aldehyde dehydrogenase 3
family, member B2 protein.
Length = 385
Score = 131 bits (317), Expect = 5e-30
Identities = 98/341 (28%), Positives = 160/341 (46%), Gaps = 13/341 (3%)
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E + T + + +
Sbjct: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
+V G ++ G L H D I FTGS VGK++ AA T +L VTLELGGK+P
Sbjct: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVMTAA-TKHLTPVTLELGGKNPC 136
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
+ ++ D +F+ GQ CVA + + ++ + A++ G+
Sbjct: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDP 195
Query: 323 DESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTI 382
S G I++ ++ L+ G+ +A G + + YI PTV DV + +
Sbjct: 196 QSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRYIAPTVLVDVQETEPV 249
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
+EEIFGP+ I+ +++E I N LA F+ + Q + +G+ N
Sbjct: 250 MQEEIFGPILPIVNVQSVDEAIKFINWQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNE 309
Query: 443 YLTMAH--QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
T PFGG SG+GR +G + + +T +++
Sbjct: 310 GFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA 350
>BC007685-1|AAH07685.1| 385|Homo sapiens aldehyde dehydrogenase 3
family, member B2 protein.
Length = 385
Score = 131 bits (317), Expect = 5e-30
Identities = 98/341 (28%), Positives = 160/341 (46%), Gaps = 13/341 (3%)
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E + T + + +
Sbjct: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
+V G ++ G L H D I FTGS VGK++ AA T +L VTLELGGK+P
Sbjct: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVMTAA-TKHLTPVTLELGGKNPC 136
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
+ ++ D +F+ GQ CVA + + ++ + A++ G+
Sbjct: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDP 195
Query: 323 DESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTI 382
S G I++ ++ L+ G+ +A G + + YI PTV DV + +
Sbjct: 196 QSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRYIAPTVLVDVQETEPV 249
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
+EEIFGP+ I+ +++E I N LA F+ + Q + +G+ N
Sbjct: 250 MQEEIFGPILPIVNVQSVDEAIKFINWQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNE 309
Query: 443 YLTMAH--QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
T PFGG SG+GR +G + + +T +++
Sbjct: 310 GFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA 350
>U37519-1|AAA85441.1| 385|Homo sapiens aldehyde dehydrogenase
protein.
Length = 385
Score = 128 bits (310), Expect = 3e-29
Identities = 96/341 (28%), Positives = 158/341 (46%), Gaps = 13/341 (3%)
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
K+P G+ +I PWN P+ + L +V L AG VV+KP+E + T + + +
Sbjct: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGTLPAGNCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
+V G ++ G L H D I FTGS VGK++ AA T +L VTLELGGK+P
Sbjct: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVMTAA-TKHLTPVTLELGGKNPC 136
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
+ ++ D +F+ GQ CVA + + ++ + A++ G+
Sbjct: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDP 195
Query: 323 DESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTI 382
S G I++ ++ L+ G+ +A G + + YI PTV DV + +
Sbjct: 196 QSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRYIAPTVLVDVQETEPV 249
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
+EEIFGP+ I+ +++E I N LA F+ + Q + +G+ N
Sbjct: 250 MQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSRQVVNQMLERTSSGSFGGNE 309
Query: 443 YLTMAH--QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
T PFGG SG+GR +G + + +T +++
Sbjct: 310 GFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA 350
>AK092464-1|BAC03897.1| 385|Homo sapiens protein ( Homo sapiens
cDNA FLJ35145 fis, clone PLACE6009853, highly similar to
ALDEHYDE DEHYDROGENASE 8 (EC 1.2.1.5). ).
Length = 385
Score = 128 bits (310), Expect = 3e-29
Identities = 97/341 (28%), Positives = 159/341 (46%), Gaps = 13/341 (3%)
Query: 143 KQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E + T + + +
Sbjct: 21 KEPFGLVLIIAPWNYPLNLTLVLLVGALAAGNCVVLKPSEISQGTEKVLAEVLPQY-LDQ 79
Query: 203 GVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPL 262
+V G ++ G L H D I FTGS VGK++ AA T +L VTLELG K+P
Sbjct: 80 SCFAVVLGGPQETGQLLEHKLDY--IFFTGSPRVGKIVMTAA-TKHLTPVTLELGVKNPC 136
Query: 263 IIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPF 322
+ ++ D +F+ GQ CVA + + ++ + A++ G+
Sbjct: 137 YVDDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFYGDDP 195
Query: 323 DESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTI 382
S G I++ ++ L+ G+ +A G + + YI PTV DV + +
Sbjct: 196 QSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSNESDRYIAPTVLVDVQETEPV 249
Query: 383 AKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNN 442
+EEIFGP+ I+ +++E I N LA F+ + Q + +G+ N
Sbjct: 250 MQEEIFGPILPIVNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNE 309
Query: 443 YLTMAH--QAPFGGFKDSGIGRENGIKAVEAYLEEKTVIIS 481
T PFGG SG+GR +G + + +T +++
Sbjct: 310 GFTYISLLSVPFGGVGHSGMGRYHGKFTFDTFSHHRTCLLA 350
>U10868-1|AAA83428.1| 468|Homo sapiens ALDH7 protein.
Length = 468
Score = 127 bits (307), Expect = 8e-29
Identities = 100/356 (28%), Positives = 168/356 (47%), Gaps = 16/356 (4%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 91 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 149
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA +L
Sbjct: 150 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLT 205
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGK+P + ++ D +F+ GQ CVA + + ++ + A+
Sbjct: 206 PVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-AL 264
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ G+ S G I++ ++ L+ G+ +A G + + YI P
Sbjct: 265 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAP 318
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ + +
Sbjct: 319 TVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVL 378
Query: 431 KHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 379 TQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 433
>EF411198-1|ABN58743.1| 468|Homo sapiens aldehyde dehydrogenase 3B1
protein.
Length = 468
Score = 127 bits (307), Expect = 8e-29
Identities = 100/356 (28%), Positives = 168/356 (47%), Gaps = 16/356 (4%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 91 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 149
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA +L
Sbjct: 150 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLT 205
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGK+P + ++ D +F+ GQ CVA + + ++ + A+
Sbjct: 206 PVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-AL 264
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ G+ S G I++ ++ L+ G+ +A G + + YI P
Sbjct: 265 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAP 318
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ + +
Sbjct: 319 TVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVL 378
Query: 431 KHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 379 TQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 433
>BT009832-1|AAP88834.1| 468|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 468
Score = 127 bits (307), Expect = 8e-29
Identities = 100/356 (28%), Positives = 168/356 (47%), Gaps = 16/356 (4%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 91 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 149
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA +L
Sbjct: 150 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLT 205
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGK+P + ++ D +F+ GQ CVA + + ++ + A+
Sbjct: 206 PVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-AL 264
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ G+ S G I++ ++ L+ G+ +A G + + YI P
Sbjct: 265 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAP 318
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ + +
Sbjct: 319 TVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVL 378
Query: 431 KHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 379 TQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 433
>BC013584-1|AAH13584.1| 468|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 468
Score = 127 bits (307), Expect = 8e-29
Identities = 100/356 (28%), Positives = 168/356 (47%), Gaps = 16/356 (4%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 91 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 149
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA +L
Sbjct: 150 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLT 205
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGK+P + ++ D +F+ GQ CVA + + ++ + A+
Sbjct: 206 PVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-AL 264
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ G+ S G I++ ++ L+ G+ +A G + + YI P
Sbjct: 265 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAP 318
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ + +
Sbjct: 319 TVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVL 378
Query: 431 KHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 379 TQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 433
>AB209651-1|BAD92888.1| 447|Homo sapiens aldehyde dehydrogenase 3B1
variant protein.
Length = 447
Score = 127 bits (307), Expect = 8e-29
Identities = 100/356 (28%), Positives = 168/356 (47%), Gaps = 16/356 (4%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 70 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 128
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA +L
Sbjct: 129 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLT 184
Query: 251 RVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAV 310
VTLELGGK+P + ++ D +F+ GQ CVA + + ++ + A+
Sbjct: 185 PVTLELGGKNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-AL 243
Query: 311 EYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQP 370
+ G+ S G I++ ++ L+ G+ +A G + + YI P
Sbjct: 244 QSTITRFYGDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAP 297
Query: 371 TVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFS 430
TV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ + +
Sbjct: 298 TVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVL 357
Query: 431 KHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 358 TQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 412
>BC033099-1|AAH33099.1| 431|Homo sapiens aldehyde dehydrogenase 3
family, member B1 protein.
Length = 431
Score = 127 bits (306), Expect = 1e-28
Identities = 97/348 (27%), Positives = 164/348 (47%), Gaps = 15/348 (4%)
Query: 139 SYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEA 198
++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E + +
Sbjct: 61 AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKILAEVLPQY 120
Query: 199 GIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGG 258
+ + +V G ++ G L H D I FTGS VGK++ AA +L VTLELGG
Sbjct: 121 -VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAA-KHLTPVTLELGG 176
Query: 259 KSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRV 318
K+P + ++ D +F+ GQ CVA + + ++ + A++
Sbjct: 177 KNPCYVDDNCDPQTVANRVAWFRYFNAGQTCVAPDYVLCSPEMQERLLP-ALQSTITRFY 235
Query: 319 GNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVND 378
G+ S G I++ ++ L+ G+ +A G + + YI PTV DV +
Sbjct: 236 GDDPQSSPNLGRIINQKQFQRLRALLGCGR------VAIGGQSDESDRYIAPTVLVDVQE 289
Query: 379 DMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTV 438
+ +EEIFGP+ I+ +L+E I+ N LA F+ + + +G
Sbjct: 290 MEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVVKRVLTQTSSGGF 349
Query: 439 WVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 350 CGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 396
>AJ427353-1|CAD20882.1| 222|Homo sapiens succinate semialdehyde
dehydrogenase protein.
Length = 222
Score = 124 bits (300), Expect = 5e-28
Identities = 80/227 (35%), Positives = 111/227 (48%), Gaps = 9/227 (3%)
Query: 16 WVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADASQRGKL 75
W+ A TF P G+ + VA F R WR A +R L
Sbjct: 1 WLPA--AATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WREVSAKERSSL 55
Query: 76 LYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDTIPTDG 135
L K+ +L+ ++ + LA++ + ++G K + + + A ++ GD I T
Sbjct: 56 LRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIYTPA 115
Query: 136 -DSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXX 194
D + LKQP+GV +I PWN P M KV ALAAGCTVVVKPAE TP +
Sbjct: 116 KDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEL 175
Query: 195 XKEAGIPKGVVNIVPGFGEDA---GVALTHHPDVAKISFTGSLEVGK 238
+AGIP GV N++P ++A G A+ P V+KISFTGS GK
Sbjct: 176 ASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGK 222
>AK093877-1|BAC04239.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ36558 fis, clone TRACH2009107, highly similar to
ALDEHYDE DEHYDROGENASE, DIMERIC NADP-PREFERRING (EC
1.2.1.5). ).
Length = 570
Score = 123 bits (297), Expect = 1e-27
Identities = 99/334 (29%), Positives = 157/334 (47%), Gaps = 14/334 (4%)
Query: 150 GLILPWNVPILMFL-NKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIV 208
G++L P++ + ++ + +AG VV+KP+E + + + K + ++
Sbjct: 225 GVVLGRAEPLVKYPGHRPGSVCSAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVI 283
Query: 209 PGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDA 268
G + L D I +TGS VGK+I AA +L VTLELGGKSP + +
Sbjct: 284 NGGVPETTELLKERFD--HILYTGSTGVGKIIMTAAA-KHLTPVTLELGGKSPCYVDKNC 340
Query: 269 DLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYAKAIRVGNPFDESTVN 328
DL++A G F + GQ CVA + I ++ V+ + K G +S
Sbjct: 341 DLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDY 399
Query: 329 GPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIF 388
G I +V+GLIE G+K +A G A YI PT+ DV+ + +EEIF
Sbjct: 400 GRIISARHFQRVMGLIE-GQK-----VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIF 453
Query: 389 GPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLT--M 446
GPV I+ +LEE I N LA +F++N + +G V N+ +
Sbjct: 454 GPVLPIVCVRSLEEAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHIT 513
Query: 447 AHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
H PFGG +SG+G +G K+ E + ++ ++
Sbjct: 514 LHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLV 547
>BC014895-1|AAH14895.2| 802|Homo sapiens aldehyde dehydrogenase 16
family, member A1 protein.
Length = 802
Score = 120 bits (289), Expect = 1e-26
Identities = 108/465 (23%), Positives = 193/465 (41%), Gaps = 24/465 (5%)
Query: 11 FIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLADAS 70
+++ +W+ + + P G +A + Q F+ W
Sbjct: 43 YVNGKWLKPEHRNSVPCQDPITGENLASCLQAQAEDVAAAVEAARMAFKG---WSAHPGV 99
Query: 71 QRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLADKIQGDT 130
R + L + A++I++ L LES G + + G + L +
Sbjct: 100 VRAQHLTRLAEVIQKHQRLLWTLESLVTGRAVRE---VRDGDVQLAQQL------LHYHA 150
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVV--VKPAEQTPLTX 188
I + +P+GV GLILP L + ++ ALA GCTVV V PA PL
Sbjct: 151 IQASTQEEALAGWEPMGVIGLILPPTFSFLEMMWRICPALAVGCTVVALVPPASPAPLLL 210
Query: 189 XXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNN 248
E G G++N+V G + L P + K++F G+ E G+ ++++
Sbjct: 211 AQLAG---ELGPFPGILNVVSGPASLVPI-LASQPGIRKVAFCGAPEEGRALRRSLA-GE 265
Query: 249 LKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKG 308
+ L LG +S L++ + AD++ A+ + +G RL +Q ++D+ ++
Sbjct: 266 CAELGLALGTESLLLLTDTADVDSAVEGVVDAAWSDRGP---GGLRLLIQESVWDEAMRR 322
Query: 309 AVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYI 368
E +R G D + G + + + V + + +GA + G+ +Y
Sbjct: 323 LQERMGRLRSGRGLDGAVDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGDVPSERPFY- 380
Query: 369 QPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQ 428
PT+ +++ A+ E+ PV F T +E + AN T G +A +++ L AL+
Sbjct: 381 PPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALE 440
Query: 429 FSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
++ GTVW+N + P GG K+SG G + YL
Sbjct: 441 LGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYL 485
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 142 LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIP 201
L++P+GV ++ P P+L F++ + ALA G TVV+ P+ PL P
Sbjct: 657 LREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATV-FP 715
Query: 202 KGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELG 257
G+ N+V G + L H DV + + GS + + ++ A+ NLK V G
Sbjct: 716 AGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWAS-AGNLKPVWASRG 770
>BC114473-1|AAI14474.1| 265|Homo sapiens ALDH8A1 protein protein.
Length = 265
Score = 116 bits (279), Expect = 2e-25
Identities = 58/156 (37%), Positives = 90/156 (57%), Gaps = 7/156 (4%)
Query: 332 IDESMMNKVLGLIETGKKEGANLLAGG--ERIGT-----AGYYIQPTVFADVNDDMTIAK 384
+ S N+V ++ EGA + G +++ AGY++ PTV D+ D+
Sbjct: 108 VRSSFANQVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAGYFMLPTVITDIKDESCCMT 167
Query: 385 EEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYL 444
EEIFGPV ++ FD+ EEVI+RANN YGLAA ++++N+ + +K +++G VW N +L
Sbjct: 168 EEIFGPVTCVVPFDSEEEVIERANNVKYGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL 227
Query: 445 TMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVII 480
PFGG K SGIGRE + + + E KT+ +
Sbjct: 228 IRELNLPFGGMKSSGIGREGAKDSYDFFTEIKTITV 263
Score = 91.9 bits (218), Expect = 5e-18
Identities = 51/116 (43%), Positives = 69/116 (59%), Gaps = 1/116 (0%)
Query: 170 LAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKIS 229
+AAG TV+ KP+E T +T +AG+P GVVNIV G G G AL HP+V IS
Sbjct: 1 MAAGNTVIAKPSELTSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLIS 60
Query: 230 FTGSLEVGKLIQKAAGTNNLKRVTLELGGKSPLIIMNDADLNLAIPYAGSGVFFHQ 285
FTGS + I + + + K+++LELGGK+P II DA+L+ IP F +Q
Sbjct: 61 FTGSQPTAERITQLSAP-HCKKLSLELGGKNPAIIFEDANLDECIPATVRSSFANQ 115
>BC070030-1|AAH70030.1| 253|Homo sapiens ALDH9A1 protein protein.
Length = 253
Score = 109 bits (261), Expect = 3e-23
Identities = 65/191 (34%), Positives = 94/191 (49%), Gaps = 2/191 (1%)
Query: 64 WRLADASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIPDSVRYLGSLA 123
W +R ++L + A +I + +A +E +NG + + Y LA
Sbjct: 65 WSQKSGMERCRILLEAARIIREREDEIATMECINNGKSIFEARLDIDISWQCLEYYAGLA 124
Query: 124 DKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQ 183
+ G+ I G SF YT ++P+GVC I WN P + K ALA G +V KP+
Sbjct: 125 ASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPF 184
Query: 184 TPLTXXXXXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKA 243
TP++ EAG+P G+ N+V G G G L HPDVAK+SFTGS+ G I +
Sbjct: 185 TPVSALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEM 243
Query: 244 AGTNNLKRVTL 254
+ +K VTL
Sbjct: 244 S-AKGIKPVTL 253
>BC045645-1|AAH45645.1| 267|Homo sapiens ALDH1L1 protein protein.
Length = 267
Score = 93.5 bits (222), Expect = 2e-18
Identities = 54/144 (37%), Positives = 77/144 (53%), Gaps = 6/144 (4%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 125 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIS 183
Query: 69 ASQRGKLLYKFADLIERDFEYLAKLESYDNGMVYKNCLRILSGIP-DSVRYLGSLADKIQ 127
A RG+L+Y+ ADL+E+ E LA +E+ D G VY L+ G+ + RY DKIQ
Sbjct: 184 ARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 243
Query: 128 GDTIPTD----GDSFSYTLKQPVG 147
G TIP + + + T K+PVG
Sbjct: 244 GSTIPINQARPNRNLTLTRKEPVG 267
>AK074136-1|BAB84962.1| 358|Homo sapiens FLJ00209 protein protein.
Length = 358
Score = 74.1 bits (174), Expect = 1e-12
Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 5/220 (2%)
Query: 254 LELGGKSPLIIMNDADLNLAIPYAGSGVFFHQGQICVAASRLYVQSGIYDKFVKGAVEYA 313
L LG +S L++ + AD++ A+ + +G RL +Q ++D+ ++ E
Sbjct: 18 LALGTESLLLLTDTADVDSAVEGVVDAAWSDRGP---GGLRLLIQESVWDEAMRRLQERM 74
Query: 314 KAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTAGYYIQPTVF 373
+R G D + G + + + V + + +GA + G+ +Y PT+
Sbjct: 75 GRLRSGRGLDGAVDMGAR-GAAACDLVQRFVREAQSQGAQVFQAGDVPSERPFY-PPTLV 132
Query: 374 ADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNALQFSKHV 433
+++ A+ E+ PV F T +E + AN T G +A +++ L AL+ +
Sbjct: 133 SNLPPASPCAQVEVPWPVVVASPFRTAKEALLVANGTPRGGSASVWSERLGQALELGYGL 192
Query: 434 EAGTVWVNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYL 473
+ GTVW+N + P GG K+SG G + YL
Sbjct: 193 QVGTVWINAHGLRDPSVPTGGCKESGCSWHGGPDGLYEYL 232
>BC014168-1|AAH14168.2| 159|Homo sapiens ALDH3B1 protein protein.
Length = 159
Score = 58.4 bits (135), Expect = 5e-08
Identities = 35/120 (29%), Positives = 59/120 (49%), Gaps = 4/120 (3%)
Query: 367 YIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEVIDRANNTNYGLAAGIFTTNLNNA 426
YI PTV DV + + +EEIFGP+ I+ +L+E I+ N LA F+ +
Sbjct: 6 YIAPTVLVDVQEMEPVMQEEIFGPILPIVNVQSLDEAIEFINRREKPLALYAFSNSSQVV 65
Query: 427 LQFSKHVEAGTVWVNN---YLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKTVIISLP 483
+ +G N+ ++T+A PFGG SG+GR +G + + + + ++ P
Sbjct: 66 KRVLTQTSSGGFCGNDGFMHMTLA-SLPFGGVGASGMGRYHGKFSFDTFSHHRACLLRSP 124
>BC042142-1|AAH42142.1| 481|Homo sapiens ALDH16A1 protein protein.
Length = 481
Score = 58.0 bits (134), Expect = 7e-08
Identities = 35/130 (26%), Positives = 60/130 (46%), Gaps = 1/130 (0%)
Query: 344 IETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFDTLEEV 403
+ + +GA + G+ +Y PT+ +++ A+ E+ PV F T +E
Sbjct: 36 VREAQSQGAQVFQAGDVPSERPFY-PPTLVSNLPPASPCAQVEVPWPVVVASPFRTAKEA 94
Query: 404 IDRANNTNYGLAAGIFTTNLNNALQFSKHVEAGTVWVNNYLTMAHQAPFGGFKDSGIGRE 463
+ AN T G +A +++ L AL+ ++ GTVW+N + P GG K+SG
Sbjct: 95 LLVANGTPRGGSASVWSERLGQALELGYGLQVGTVWINAHGLRDPSVPTGGCKESGCSWH 154
Query: 464 NGIKAVEAYL 473
G + YL
Sbjct: 155 GGPDGLYEYL 164
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 142 LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIP 201
L++P+GV ++ P P+L F++ + ALA G TVV+ P+ PL P
Sbjct: 336 LREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATV-FP 394
Query: 202 KGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELG 257
G+ N+V G + L H DV + + GS + + ++ A+ NLK V G
Sbjct: 395 AGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWAS-AGNLKPVWASRG 449
>BC002553-1|AAH02553.1| 230|Homo sapiens ALDH3B1 protein protein.
Length = 230
Score = 57.6 bits (133), Expect = 9e-08
Identities = 40/121 (33%), Positives = 62/121 (51%), Gaps = 4/121 (3%)
Query: 131 IPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXX 190
+ T DS ++ K+P G+ +I PWN P+ + L +V ALAAG VV+KP+E +
Sbjct: 91 LATQLDS-AFIRKEPFGLVLIIAPWNYPLNLTLVPLVGALAAGNCVVLKPSEISKNVEKI 149
Query: 191 XXXXXKEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLK 250
+ + + +V G ++ G L H D I FTGS VGK++ AA + K
Sbjct: 150 LAEVLPQY-VDQSCFAVVLGGPQETGQLLEHRFDY--IFFTGSPRVGKIVMTAAAKHPSK 206
Query: 251 R 251
+
Sbjct: 207 Q 207
>BC035641-1|AAH35641.1| 216|Homo sapiens ALDH16A1 protein protein.
Length = 216
Score = 54.0 bits (124), Expect = 1e-06
Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Query: 142 LKQPVGVCGLILPWNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIP 201
L++P+GV ++ P P+L F++ + ALA G TVV+ P+ PL P
Sbjct: 71 LREPLGVLAVVCPDEWPLLAFVSLLAPALAYGNTVVMVPSAACPLLALEVCQDMATV-FP 129
Query: 202 KGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLELG 257
G+ N+V G + L H DV + + GS + + ++ A+ NLK V G
Sbjct: 130 AGLANVVTGDRDHLTRCLALHQDVQAMWYFGSAQGSQFVEWAS-AGNLKPVWASRG 184
>BC027241-1|AAH27241.1| 505|Homo sapiens ALDH1L1 protein protein.
Length = 505
Score = 50.8 bits (116), Expect = 1e-05
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 9 KLFIDNEWVDAKDGETFDTFSPHDGSVIAKVAKGQXXXXXXXXXXXXXXFQRNSEWRLAD 68
+LFI E+VDA+ +T +T +P DGSVI +V+ Q F+ N W
Sbjct: 423 QLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFE-NGRWGKIS 481
Query: 69 ASQRGKLLYK 78
A RG+L+Y+
Sbjct: 482 ARDRGRLMYR 491
>AK124965-1|BAC86008.1| 131|Homo sapiens protein ( Homo sapiens
cDNA FLJ42975 fis, clone BRTHA2002608, weakly similar
to Homo sapiens aldehyde dehydrogenase 1 family, member
A3 (ALDH1A3). ).
Length = 131
Score = 50.8 bits (116), Expect = 1e-05
Identities = 24/48 (50%), Positives = 29/48 (60%)
Query: 155 WNVPILMFLNKVVTALAAGCTVVVKPAEQTPLTXXXXXXXXKEAGIPK 202
WN P+LM + K+ AL G T+V+KPAEQTPLT KE PK
Sbjct: 20 WNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEVRHPK 67
>AF164120-1|AAD48447.1| 38|Homo sapiens mitochondrial aldehyde
dehydrogenase 2 protein.
Length = 38
Score = 41.1 bits (92), Expect = 0.008
Identities = 20/38 (52%), Positives = 24/38 (63%)
Query: 440 VNNYLTMAHQAPFGGFKDSGIGRENGIKAVEAYLEEKT 477
VN Y Q+PFGG+K SG GRE G ++AY E KT
Sbjct: 1 VNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKT 38
>AB015229-1|BAA34788.1| 25|Homo sapiens RALDH2-T protein.
Length = 25
Score = 34.3 bits (75), Expect = 0.97
Identities = 16/24 (66%), Positives = 19/24 (79%)
Query: 68 DASQRGKLLYKFADLIERDFEYLA 91
DAS+RG+LL K ADL+ERD LA
Sbjct: 2 DASERGRLLDKLADLVERDRAVLA 25
>BC113400-1|AAI13401.1| 476|Homo sapiens chromosome 20 open reading
frame 185 protein.
Length = 476
Score = 32.7 bits (71), Expect = 3.0
Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
+E +PK ++ ++PGF GV L+ H K+ S +G L+Q AA N RV L
Sbjct: 98 EELTLPKVLLKLLPGF----GVQLSLH---TKVGMHCSGPLGGLLQLAAEVNVTSRVALA 150
Query: 256 LGGK-SPLIIM 265
+ + +P++I+
Sbjct: 151 VSSRGTPILIL 161
>BC113398-1|AAI13399.1| 476|Homo sapiens chromosome 20 open reading
frame 185 protein.
Length = 476
Score = 32.7 bits (71), Expect = 3.0
Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
+E +PK ++ ++PGF GV L+ H K+ S +G L+Q AA N RV L
Sbjct: 98 EELTLPKVLLKLLPGF----GVQLSLH---TKVGMHCSGPLGGLLQLAAEVNVTSRVALA 150
Query: 256 LGGK-SPLIIM 265
+ + +P++I+
Sbjct: 151 VSSRGTPILIL 161
>AL121756-8|CAI22531.1| 476|Homo sapiens chromosome 20 open reading
frame 185 protein.
Length = 476
Score = 32.7 bits (71), Expect = 3.0
Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
+E +PK ++ ++PGF GV L+ H K+ S +G L+Q AA N RV L
Sbjct: 98 EELTLPKVLLKLLPGF----GVQLSLH---TKVGMHCSGPLGGLLQLAAEVNVTSRVALA 150
Query: 256 LGGK-SPLIIM 265
+ + +P++I+
Sbjct: 151 VSSRGTPILIL 161
>AF549189-1|AAP84989.1| 476|Homo sapiens RYA3 protein.
Length = 476
Score = 32.7 bits (71), Expect = 3.0
Identities = 23/71 (32%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Query: 196 KEAGIPKGVVNIVPGFGEDAGVALTHHPDVAKISFTGSLEVGKLIQKAAGTNNLKRVTLE 255
+E +PK ++ ++PGF GV L+ H K+ S +G L+Q AA N RV L
Sbjct: 98 EELTLPKVLLKLLPGF----GVQLSLH---TKVGMHCSGPLGGLLQLAAEVNVTSRVALA 150
Query: 256 LGGK-SPLIIM 265
+ + +P++I+
Sbjct: 151 VSSRGTPILIL 161
>BC035627-1|AAH35627.1| 523|Homo sapiens solute carrier family 7,
(neutral amino acid transporter, y+ system) member 10
protein.
Length = 523
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 116 VRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCT 175
V LGSL G IP G ++Y + G+ G +L W+ ++M+ +
Sbjct: 85 VTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSN 144
Query: 176 VVVKP 180
V++P
Sbjct: 145 YVLQP 149
>AJ277731-1|CAC81900.1| 523|Homo sapiens ASC1 protein protein.
Length = 523
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 116 VRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCT 175
V LGSL G IP G ++Y + G+ G +L W+ ++M+ +
Sbjct: 85 VTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSN 144
Query: 176 VVVKP 180
V++P
Sbjct: 145 YVLQP 149
>AF340165-1|AAK93960.1| 523|Homo sapiens amino acid transporter
protein.
Length = 523
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 116 VRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCT 175
V LGSL G IP G ++Y + G+ G +L W+ ++M+ +
Sbjct: 85 VTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSN 144
Query: 176 VVVKP 180
V++P
Sbjct: 145 YVLQP 149
>AB037670-1|BAB03213.1| 523|Homo sapiens asc-type amino acid
transporter 1 protein.
Length = 523
Score = 31.9 bits (69), Expect = 5.2
Identities = 17/65 (26%), Positives = 29/65 (44%)
Query: 116 VRYLGSLADKIQGDTIPTDGDSFSYTLKQPVGVCGLILPWNVPILMFLNKVVTALAAGCT 175
V LGSL G IP G ++Y + G+ G +L W+ ++M+ +
Sbjct: 85 VTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSN 144
Query: 176 VVVKP 180
V++P
Sbjct: 145 YVLQP 149
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy chain
DNAH5 protein.
Length = 4624
Score = 31.5 bits (68), Expect = 6.9
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 343 LIETGKKEGANLLAGGERIGTAGYYIQPTVFADVNDDMTIAKEEIFGPVQSILKFD-TLE 401
LI+T K+G +L GE+ GTA I + + + + K F + L F T+E
Sbjct: 2575 LIQTIAKQGKAVLLIGEQ-GTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIE 2633
Query: 402 EVIDRANNTNYGLAAG 417
+D+ T YG AG
Sbjct: 2634 SYVDKRMGTTYGPPAG 2649
>AL590438-3|CAH71529.1| 1257|Homo sapiens PR domain containing 16
protein.
Length = 1257
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL590438-2|CAH71531.1| 1276|Homo sapiens PR domain containing 16
protein.
Length = 1276
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL512383-3|CAH71133.1| 1257|Homo sapiens PR domain containing 16
protein.
Length = 1257
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL512383-2|CAH71132.1| 1276|Homo sapiens PR domain containing 16
protein.
Length = 1276
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL354743-3|CAI22789.1| 1257|Homo sapiens PR domain containing 16
protein.
Length = 1257
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL354743-1|CAI22788.1| 1276|Homo sapiens PR domain containing 16
protein.
Length = 1276
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL008733-3|CAI19631.1| 1257|Homo sapiens PR domain containing 16
protein.
Length = 1257
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AL008733-1|CAI19630.1| 1276|Homo sapiens PR domain containing 16
protein.
Length = 1276
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AB078876-1|BAB84297.1| 1257|Homo sapiens transcription factor MEL1
protein.
Length = 1257
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 164 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 223
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 224 LDEEPTFRCDECDELFQSKLDL 245
>AB051462-1|BAB21766.2| 1286|Homo sapiens KIAA1675 protein protein.
Length = 1286
Score = 31.1 bits (67), Expect = 9.1
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 308 GAVEYAKAIRVGNPFDESTVNGPQIDESMMNKVLGLIETGKKEGANLLAGGERIGTA--G 365
GA + K IRV D+ + QI E + KV+ IE G++ ++ G +GT G
Sbjct: 174 GAGSWLKYIRVACSCDDQNLTMCQISEQIYYKVIKDIEPGEELLVHVKEGVYPLGTVPPG 233
Query: 366 YYIQPTVFADVNDDMTIAKEEI 387
+PT D D++ +K ++
Sbjct: 234 LDEEPTFRCDECDELFQSKLDL 255
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.137 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 67,069,876
Number of Sequences: 224733
Number of extensions: 2740675
Number of successful extensions: 4534
Number of sequences better than 10.0: 141
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4105
Number of HSP's gapped (non-prelim): 151
length of query: 486
length of database: 73,234,838
effective HSP length: 93
effective length of query: 393
effective length of database: 52,334,669
effective search space: 20567524917
effective search space used: 20567524917
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 67 (31.1 bits)
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