Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002450-TA|BGIBMGA002450-PA|IPR001360|Glycoside
hydrolase, family 1
(419 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 349 8e-96
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 349 1e-95
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 349 1e-95
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 345 1e-94
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 330 5e-90
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 329 1e-89
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 329 1e-89
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 329 1e-89
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 328 2e-89
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 326 9e-89
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 325 2e-88
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 235 2e-61
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 235 2e-61
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 235 2e-61
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 235 2e-61
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 221 3e-57
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 221 3e-57
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 221 3e-57
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 166 1e-40
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 153 1e-36
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 93 1e-18
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 75 6e-13
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 75 6e-13
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 74 1e-12
AB002340-1|BAA20800.3| 2467|Homo sapiens KIAA0342 protein protein. 33 1.4
Y10523-1|CAA71535.1| 1336|Homo sapiens immunoglobulin-like domai... 31 7.6
X83957-1|CAA58788.1| 6669|Homo sapiens nebulin protein. 31 7.6
U35637-1|AAB02622.1| 3007|Homo sapiens nebulin protein. 31 7.6
BT006631-1|AAP35277.1| 342|Homo sapiens sorting nexin 15 protein. 31 7.6
BC063884-1|AAH63884.1| 1336|Homo sapiens immunoglobulin superfam... 31 7.6
BC033798-1|AAH33798.1| 430|Homo sapiens spermatogenic leucine z... 31 7.6
BC014520-1|AAH14520.1| 342|Homo sapiens sorting nexin 15 protein. 31 7.6
BC012767-1|AAH12767.1| 342|Homo sapiens sorting nexin 15 protein. 31 7.6
BC009897-1|AAH09897.1| 342|Homo sapiens sorting nexin 15 protein. 31 7.6
AL590806-2|CAI41249.1| 1336|Homo sapiens immunoglobulin superfam... 31 7.6
AL590806-1|CAI41248.1| 1327|Homo sapiens immunoglobulin superfam... 31 7.6
AK098575-1|BAC05340.1| 382|Homo sapiens protein ( Homo sapiens ... 31 7.6
AF333098-1|AAK17995.1| 430|Homo sapiens testis-specific protein... 31 7.6
AF175268-1|AAF89956.1| 255|Homo sapiens sorting nexin 15A protein. 31 7.6
AF175267-1|AAF89955.1| 342|Homo sapiens sorting nexin 15 protein. 31 7.6
AF034198-1|AAC52057.1| 1327|Homo sapiens IGSF1 protein. 31 7.6
AF001435-1|AAB81205.1| 152|Homo sapiens unknown protein. 31 7.6
AC009497-1|AAY14651.1| 2802|Homo sapiens unknown protein. 31 7.6
AB209439-1|BAD92676.1| 267|Homo sapiens sorting nexin 15 isofor... 31 7.6
AB002362-1|BAA20819.2| 1437|Homo sapiens KIAA0364 protein. 31 7.6
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 349 bits (859), Expect = 8e-96
Identities = 178/417 (42%), Positives = 245/417 (58%), Gaps = 14/417 (3%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWDT+ H P + + GD+A DSYHK ED+ ++ LGV +YR SISW R+L
Sbjct: 1399 DGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRIL 1457
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVD 124
P+GT+ I+ G YY L + LL A+I P VT++HWD+P D+ GW N IV F +
Sbjct: 1458 PDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKE 1517
Query: 125 YARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSH-GVGEYLCAHYLILSHAK 183
YA V F GD +K W T+NEP YQGYG AP + + G Y+ H LI +HA+
Sbjct: 1518 YADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAE 1577
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
A+HLY ++ Q G + IT+ + P+DP N +DV A R Y+Q F +AHPI
Sbjct: 1578 AWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQ-----FMGGWFAHPI 1632
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
F GDY ++ RI + SLA G +SRLP FT E + I G+ DFFG NHYTT L
Sbjct: 1633 FK-NGDYSEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVL--AY 1689
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ +I S D D V D W G+ WL + P GFR++LN++ + Y + PI VT
Sbjct: 1690 NLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEY-NDPPIYVT 1748
Query: 364 ENGVGDKGQ--LKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENGV + + L D RI Y Y+ + L A+ +D ++ GY W+ MD+FEW+ G+
Sbjct: 1749 ENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGF 1804
Score = 345 bits (849), Expect = 1e-94
Identities = 170/417 (40%), Positives = 239/417 (57%), Gaps = 12/417 (2%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG SIWD + H D + GDIA DSYH+ D+ +++AL VK YR SISW R
Sbjct: 923 DADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSR 982
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
+ P G +++I++ G YY L L+ +NI P+VTLFHWD+P D+ GW NP ++D F
Sbjct: 983 IFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLF 1042
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA F +GD +K W T NEP + GYG+ F P +K G Y AH +I +HA
Sbjct: 1043 DSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHAVIKAHA 1102
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+ YH Y+++++ QKG + ++L PK P +DV A LQ F +AHP
Sbjct: 1103 RVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQ-----FSLGWFAHP 1157
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF GDYP ++ ++ N S Q A SRLP FT EE + IR ++D F LN Y + ++
Sbjct: 1158 IF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQH 1216
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
+ PS + D ++ E+DP W P T P G R+LLN++ + YG +IPI +
Sbjct: 1217 KTPRL--NPPSYEDDQEMAEEEDPSW--PSTAMNRAAPWGTRRLLNWIKEEYG-DIPIYI 1271
Query: 363 TENGVG-DKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENGVG +D DRI Y Y+ + L A D ++ GY AW+LMD+FEW +GY
Sbjct: 1272 TENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGY 1328
Score = 299 bits (735), Expect = 9e-81
Identities = 155/417 (37%), Positives = 228/417 (54%), Gaps = 14/417 (3%)
Query: 6 GKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLLP 65
G+G SIWD T ++ ++A+DSYHK DV L+ L + Y+ SISW R+ P
Sbjct: 405 GRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFP 462
Query: 66 NGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVDY 125
G ++ S G YY L + L A I P+ TLFHWD+P D GW N +VD F+DY
Sbjct: 463 MGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDY 522
Query: 126 ARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAKAY 185
A F+ +GD +K W T +EP Y GYG P I GV + AH ++ +HA+ +
Sbjct: 523 AAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTW 582
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H Y +P Q+G VGI L++ P P +D+ A + LHF +AHP+F
Sbjct: 583 HHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERF-----LHFMLGWFAHPVF- 636
Query: 246 AEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPSEM 305
+GDYP +R +I M+ ++LP FT E ++++GS+DF GL+HYT+ L+S +
Sbjct: 637 VDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQ 696
Query: 306 EFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGR-EIPIIVTE 364
+ IPS D + W + + W+ V P G R+LL +VS Y R ++PI +
Sbjct: 697 --NTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAG 754
Query: 365 NG--VGDKGQLKDYD-RISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
NG +G+ L D R+ YFN+Y+ ++L AI ED+ ++ Y A +L+D FE GY
Sbjct: 755 NGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGY 811
Score = 65.3 bits (152), Expect = 4e-10
Identities = 45/161 (27%), Positives = 76/161 (47%), Gaps = 16/161 (9%)
Query: 46 IKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPT 105
+ A + +Y++ +SW +LLP G++ N + YR L + L A + P+V L H +P
Sbjct: 79 LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPA 138
Query: 106 PFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKS 165
LR D F DYA AF+ +GD++ W T ++ + + + A +++
Sbjct: 139 --STLR--RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQT 194
Query: 166 HGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDA 206
L +H KAY +Y + + Q GK+ I L A
Sbjct: 195 -----------LSDAHRKAYEIYHESY-AFQGGKLSIVLRA 223
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 349 bits (858), Expect = 1e-95
Identities = 178/417 (42%), Positives = 245/417 (58%), Gaps = 14/417 (3%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWDT+ H P + + GD+A DSYHK ED+ ++ LGV +YR SISW R+L
Sbjct: 1399 DGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRIL 1457
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVD 124
P+GT+ I+ G YY L + LL A+I P VT++HWD+P D+ GW N IV F +
Sbjct: 1458 PDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKE 1517
Query: 125 YARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSH-GVGEYLCAHYLILSHAK 183
YA V F GD +K W T+NEP YQGYG AP + + G Y+ H LI +HA+
Sbjct: 1518 YADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAE 1577
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
A+HLY ++ Q G + IT+ + P+DP N +DV A R Y+Q F +AHPI
Sbjct: 1578 AWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQ-----FMGGWFAHPI 1632
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
F GDY ++ RI + SLA G +SRLP FT E + I G+ DFFG NHYTT L
Sbjct: 1633 FK-NGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVL--AY 1689
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ +I S D D V D W G+ WL + P GFR++LN++ + Y + PI VT
Sbjct: 1690 NLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEY-NDPPIYVT 1748
Query: 364 ENGVGDKGQ--LKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENGV + + L D RI Y Y+ + L A+ +D ++ GY W+ MD+FEW+ G+
Sbjct: 1749 ENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGF 1804
Score = 345 bits (849), Expect = 1e-94
Identities = 170/417 (40%), Positives = 239/417 (57%), Gaps = 12/417 (2%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG SIWD + H D + GDIA DSYH+ D+ +++AL VK YR SISW R
Sbjct: 923 DADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSR 982
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
+ P G +++I++ G YY L L+ +NI P+VTLFHWD+P D+ GW NP ++D F
Sbjct: 983 IFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLF 1042
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA F +GD +K W T NEP + GYG+ F P +K G Y AH +I +HA
Sbjct: 1043 DSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHTVIKAHA 1102
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+ YH Y+++++ QKG + ++L PK P +DV A LQ F +AHP
Sbjct: 1103 RVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQ-----FSLGWFAHP 1157
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF GDYP ++ ++ N S Q A SRLP FT EE + IR ++D F LN Y + ++
Sbjct: 1158 IF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQH 1216
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
+ PS + D ++ E+DP W P T P G R+LLN++ + YG +IPI +
Sbjct: 1217 KTPRL--NPPSYEDDQEMAEEEDPSW--PSTAMNRAAPWGTRRLLNWIKEEYG-DIPIYI 1271
Query: 363 TENGVG-DKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENGVG +D DRI Y Y+ + L A D ++ GY AW+LMD+FEW +GY
Sbjct: 1272 TENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGY 1328
Score = 299 bits (735), Expect = 9e-81
Identities = 155/417 (37%), Positives = 228/417 (54%), Gaps = 14/417 (3%)
Query: 6 GKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLLP 65
G+G SIWD T ++ ++A+DSYHK DV L+ L + Y+ SISW R+ P
Sbjct: 405 GRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFP 462
Query: 66 NGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVDY 125
G ++ S G YY L + L A I P+ TLFHWD+P D GW N +VD F+DY
Sbjct: 463 MGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDY 522
Query: 126 ARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAKAY 185
A F+ +GD +K W T +EP Y GYG P I GV + AH ++ +HA+ +
Sbjct: 523 AAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTW 582
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H Y +P Q+G VGI L++ P P +D+ A + LHF +AHP+F
Sbjct: 583 HHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERF-----LHFMLGWFAHPVF- 636
Query: 246 AEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPSEM 305
+GDYP +R +I M+ ++LP FT E ++++GS+DF GL+HYT+ L+S +
Sbjct: 637 VDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQ 696
Query: 306 EFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGR-EIPIIVTE 364
+ IPS D + W + + W+ V P G R+LL +VS Y R ++PI +
Sbjct: 697 --NTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAG 754
Query: 365 NG--VGDKGQLKDYD-RISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
NG +G+ L D R+ YFN+Y+ ++L AI ED+ ++ Y A +L+D FE GY
Sbjct: 755 NGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGY 811
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 16/161 (9%)
Query: 46 IKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPT 105
+ A + +Y++ +SW +LLP G++ N + YR L + L A + P+V L H +P
Sbjct: 79 LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPA 138
Query: 106 PFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKS 165
LR D F DYA AF+ +GD++ W T ++ + + + A +++
Sbjct: 139 --STLR--RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQT 194
Query: 166 HGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDA 206
L +H KAY +Y + + Q GK+ + L A
Sbjct: 195 -----------LSDAHRKAYEIYHESY-AFQGGKLSVVLRA 223
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 349 bits (858), Expect = 1e-95
Identities = 178/417 (42%), Positives = 245/417 (58%), Gaps = 14/417 (3%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWDT+ H P + + GD+A DSYHK ED+ ++ LGV +YR SISW R+L
Sbjct: 1399 DGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRIL 1457
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVD 124
P+GT+ I+ G YY L + LL A+I P VT++HWD+P D+ GW N IV F +
Sbjct: 1458 PDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKE 1517
Query: 125 YARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSH-GVGEYLCAHYLILSHAK 183
YA V F GD +K W T+NEP YQGYG AP + + G Y+ H LI +HA+
Sbjct: 1518 YADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPGVSNRPGTAPYIVGHNLIKAHAE 1577
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
A+HLY ++ Q G + IT+ + P+DP N +DV A R Y+Q F +AHPI
Sbjct: 1578 AWHLYNDVYRASQGGVISITISSDWAEPRDPSNQEDVEAARRYVQ-----FMGGWFAHPI 1632
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
F GDY ++ RI + SLA G +SRLP FT E + I G+ DFFG NHYTT L
Sbjct: 1633 FK-NGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVL--AY 1689
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ +I S D D V D W G+ WL + P GFR++LN++ + Y + PI VT
Sbjct: 1690 NLNYATAISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEY-NDPPIYVT 1748
Query: 364 ENGVGDKGQ--LKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENGV + + L D RI Y Y+ + L A+ +D ++ GY W+ MD+FEW+ G+
Sbjct: 1749 ENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGF 1804
Score = 345 bits (849), Expect = 1e-94
Identities = 170/417 (40%), Positives = 239/417 (57%), Gaps = 12/417 (2%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG SIWD + H D + GDIA DSYH+ D+ +++AL VK YR SISW R
Sbjct: 923 DADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSR 982
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
+ P G +++I++ G YY L L+ +NI P+VTLFHWD+P D+ GW NP ++D F
Sbjct: 983 IFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLF 1042
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA F +GD +K W T NEP + GYG+ F P +K G Y AH +I +HA
Sbjct: 1043 DSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHAVIKAHA 1102
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+ YH Y+++++ QKG + ++L PK P +DV A LQ F +AHP
Sbjct: 1103 RVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQ-----FSLGWFAHP 1157
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF GDYP ++ ++ N S Q A SRLP FT EE + IR ++D F LN Y + ++
Sbjct: 1158 IF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQH 1216
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
+ PS + D ++ E+DP W P T P G R+LLN++ + YG +IPI +
Sbjct: 1217 KTPRL--NPPSYEDDQEMAEEEDPSW--PSTAMNRAAPWGTRRLLNWIKEEYG-DIPIYI 1271
Query: 363 TENGVG-DKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENGVG +D DRI Y Y+ + L A D ++ GY AW+LMD+FEW +GY
Sbjct: 1272 TENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGY 1328
Score = 299 bits (735), Expect = 9e-81
Identities = 155/417 (37%), Positives = 228/417 (54%), Gaps = 14/417 (3%)
Query: 6 GKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLLP 65
G+G SIWD T ++ ++A+DSYHK DV L+ L + Y+ SISW R+ P
Sbjct: 405 GRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFP 462
Query: 66 NGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVDY 125
G ++ S G YY L + L A I P+ TLFHWD+P D GW N +VD F+DY
Sbjct: 463 MGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWDLPQALQDHGGWQNESVVDAFLDY 522
Query: 126 ARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAKAY 185
A F+ +GD +K W T +EP Y GYG P I GV + AH ++ +HA+ +
Sbjct: 523 AAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVAHLVLKAHARTW 582
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H Y +P Q+G VGI L++ P P +D+ A + LHF +AHP+F
Sbjct: 583 HHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERF-----LHFMLGWFAHPVF- 636
Query: 246 AEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPSEM 305
+GDYP +R +I M+ ++LP FT E ++++GS+DF GL+HYT+ L+S +
Sbjct: 637 VDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQ 696
Query: 306 EFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGR-EIPIIVTE 364
+ IPS D + W + + W+ V P G R+LL +VS Y R ++PI +
Sbjct: 697 --NTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAG 754
Query: 365 NG--VGDKGQLKDYD-RISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
NG +G+ L D R+ YFN+Y+ ++L AI ED+ ++ Y A +L+D FE GY
Sbjct: 755 NGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGY 811
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/161 (27%), Positives = 76/161 (47%), Gaps = 16/161 (9%)
Query: 46 IKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPT 105
+ A + +Y++ +SW +LLP G++ N + YR L + L A + P+V L H +P
Sbjct: 79 LHASQITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPA 138
Query: 106 PFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKS 165
LR D F DYA AF+ +GD++ W T ++ + + + A +++
Sbjct: 139 --STLR--RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQLQT 194
Query: 166 HGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDA 206
L +H KAY +Y + + Q GK+ + L A
Sbjct: 195 -----------LSDAHRKAYEIYHESY-AFQGGKLSVVLRA 223
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 345 bits (849), Expect = 1e-94
Identities = 170/417 (40%), Positives = 239/417 (57%), Gaps = 12/417 (2%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG SIWD + H D + GDIA DSYH+ D+ +++AL VK YR SISW R
Sbjct: 355 DADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNMLRALKVKAYRFSISWSR 414
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
+ P G +++I++ G YY L L+ +NI P+VTLFHWD+P D+ GW NP ++D F
Sbjct: 415 IFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQALQDIGGWENPALIDLF 474
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA F +GD +K W T NEP + GYG+ F P +K G Y AH +I +HA
Sbjct: 475 DSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIAHTVIKAHA 534
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+ YH Y+++++ QKG + ++L PK P +DV A LQ F +AHP
Sbjct: 535 RVYHTYDEKYRQEQKGVISLSLSTHWAEPKSPGVPRDVEAADRMLQ-----FSLGWFAHP 589
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF GDYP ++ ++ N S Q A SRLP FT EE + IR ++D F LN Y + ++
Sbjct: 590 IF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQH 648
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
+ PS + D ++ E+DP W P T P G R+LLN++ + YG +IPI +
Sbjct: 649 KTPRL--NPPSYEDDQEMAEEEDPSW--PSTAMNRAAPWGTRRLLNWIKEEYG-DIPIYI 703
Query: 363 TENGVG-DKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENGVG +D DRI Y Y+ + L A D ++ GY AW+LMD+FEW +GY
Sbjct: 704 TENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEWLNGY 760
Score = 165 bits (400), Expect = 3e-40
Identities = 80/172 (46%), Positives = 103/172 (59%), Gaps = 6/172 (3%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWDT+ H P + + GD+A DSYHK ED+ ++ LGV +YR SISW R+L
Sbjct: 831 DGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRIL 889
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYFVD 124
P+GT+ I+ G YY L + LL A+I P VT++HWD+P D+ GW N IV F +
Sbjct: 890 PDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWDLPQTLQDVGGWENETIVQRFKE 949
Query: 125 YARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHY 176
YA V F GD +K W T+NEP YQGYG AP H G +C Y
Sbjct: 950 YADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPV---H--GRLVCTSY 996
Score = 160 bits (389), Expect = 7e-39
Identities = 88/249 (35%), Positives = 139/249 (55%), Gaps = 12/249 (4%)
Query: 174 AHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLH 233
AH ++ +HA+ +H Y +P Q+G VGI L++ P P +D+ A +L H
Sbjct: 3 AHLVLKAHARTWHHYNSHHRPQQQGHVGIVLNSDWAEPLSPERPEDLRASERFL-----H 57
Query: 234 FQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLN 293
F +AHP+F +GDYP +R +I M+ ++LP FT E ++++GS+DF GL+
Sbjct: 58 FMLGWFAHPVF-VDGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLS 116
Query: 294 HYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDN 353
HYT+ L+S + + IPS D + W + + W+ V P G R+LL +VS
Sbjct: 117 HYTSRLISNAPQ--NTCIPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLE 174
Query: 354 YGR-EIPIIVTENG--VGDKGQLKDYD-RISYFNKYLYQLLLAIHEDNCNIIGYFAWTLM 409
Y R ++PI + NG +G+ L D R+ YFN+Y+ ++L AI ED+ ++ Y A +L+
Sbjct: 175 YTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLI 234
Query: 410 DDFEWSDGY 418
D FE GY
Sbjct: 235 DGFEGPSGY 243
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 330 bits (811), Expect = 5e-90
Identities = 167/418 (39%), Positives = 240/418 (57%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + +YTT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + ++ DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENK-KGELGTL-QDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 329 bits (808), Expect = 1e-89
Identities = 167/418 (39%), Positives = 238/418 (56%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + +YTT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENKKGEL--GILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 329 bits (808), Expect = 1e-89
Identities = 167/418 (39%), Positives = 238/418 (56%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + +YTT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENKKGEL--GILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 329 bits (808), Expect = 1e-89
Identities = 167/418 (39%), Positives = 238/418 (56%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + +YTT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENKKGEL--GILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 328 bits (807), Expect = 2e-89
Identities = 167/418 (39%), Positives = 238/418 (56%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWWSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + +YTT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENKKGEL--GILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 326 bits (801), Expect = 9e-89
Identities = 169/419 (40%), Positives = 236/419 (56%), Gaps = 15/419 (3%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWD + H D+A D Y+K +ED+ L++ L V +YR S+SWPRLL
Sbjct: 59 DGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQEDIILLRELHVNHYRFSLSWPRLL 118
Query: 65 PNGT-SNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPF-MDLRGWNNPVIVDYF 122
P G + ++ G +Y +L + LL +NITPIVTL HWD+P + GW N + +YF
Sbjct: 119 PTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHWDLPQLLQVKYGGWQNVSMANYF 178
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
DYA + F +GD +K W T ++P +GY + AP +K G G Y AH++I +HA
Sbjct: 179 RDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHAPGLKLRGTGLYKAAHHIIKAHA 238
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
K +H Y ++ Q+G VGI+L+ G P D N +D+ A YLQ F +A+P
Sbjct: 239 KTWHSYNTTWRSKQQGLVGISLNCDWGEPVDISNPKDLEAAERYLQ-----FCLGWFANP 293
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
I++ GDYP ++ I S QG SRLP F+ +E I+G+SDF GL H+TT ++
Sbjct: 294 IYA--GDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITE 351
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
S PS +D + DP+W G+ WL P GFR+LLN+ YG + PI V
Sbjct: 352 RNYP-SRQGPSYQNDRDLIELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYG-DPPIYV 409
Query: 363 TENGVGDK---GQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENG K QL D RI Y Y+ ++L AI +D NI GY +W+L+D FEW GY
Sbjct: 410 MENGASQKFHCTQLCDEWRIQYLKGYINEMLKAI-KDGANIKGYTSWSLLDKFEWEKGY 467
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 325 bits (799), Expect = 2e-88
Identities = 166/418 (39%), Positives = 237/418 (56%), Gaps = 13/418 (3%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMDLRGWNNPVIVDYF 122
LLP+GT+ I+ G YY + ++LLK +TPIVTL+H+D+P D GW + I++ F
Sbjct: 83 LLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFDLPQTLEDQGGWLSEAIIESF 142
Query: 123 VDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHA 182
YA+ F+ +GD +K W TINE + Y F P I G G Y AH LI +HA
Sbjct: 143 DKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPGIPHFGTGGYQAAHNLIKAHA 202
Query: 183 KAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHP 242
+++H Y+ F+ QKG V ++L A P DP + D A + + H DL+A P
Sbjct: 203 RSWHSYDSLFRKKQKGMVSLSLFAVWLEPADPNSVSDQEAAKRAITFH-----LDLFAKP 257
Query: 243 IFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSP 302
IF +GDYP V+ +I +MS QG+ SRLP FT EE K+I+G++DFF + + TT L+
Sbjct: 258 IF-IDGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKY 316
Query: 303 SEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIV 362
E + + DA++ DP W+ DW+ V P G KLL Y+ D Y + I +
Sbjct: 317 QENKRGEL--GILQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNPV-IYI 371
Query: 363 TENGV--GDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
TENG D L D R YF + +L AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 372 TENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGY 429
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 235 bits (575), Expect = 2e-61
Identities = 154/434 (35%), Positives = 217/434 (50%), Gaps = 66/434 (15%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSN----------------GDIAADSYHKFKEDVQLIKA 48
+GKG SIWDT+ H HP P S GD+A+DSY+ D + ++
Sbjct: 83 HGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRE 141
Query: 49 LGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFM 108
LGV +YR SISW R+LPNG++ + +G RYYR L E L + + P+VTL+HWD+P
Sbjct: 142 LGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQ 201
Query: 109 D-LRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHG 167
D GW N + D+F DYA + F +G +K W TI+ P+ + GY AP I+
Sbjct: 202 DAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSP 261
Query: 168 VGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYL 227
YL AH L+L+HAK +HLY F+P Q G+V I L + +PR D S
Sbjct: 262 RLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHW---INPRRMTD----HSIK 314
Query: 228 QIHK-LHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGS 286
+ K L F +A P+F +GDYP ++ NN+S S LP FT E K I+G+
Sbjct: 315 ECQKSLDFVLGWFAKPVF-IDGDYPESMK---NNLS-------SILPDFTESEKKFIKGT 363
Query: 287 SDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKL 346
+DFF L P + S +D + R + P+ R+L
Sbjct: 364 ADFFAL------CFGP-----TLSFQLLDPHMKFRQLESPN---------------LRQL 397
Query: 347 LNYVSDNYGREIPIIVTENGVGDKGQLK--DYDRISYFNKYLYQLLLAIHEDNCNIIGYF 404
L+++ + I + ENG G K D + Y K++ + L AI D ++IGY
Sbjct: 398 LSWIDLEFNHP-QIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYT 456
Query: 405 AWTLMDDFEWSDGY 418
AW+LMD FEW GY
Sbjct: 457 AWSLMDGFEWHRGY 470
Score = 166 bits (404), Expect = 1e-40
Identities = 118/374 (31%), Positives = 183/374 (48%), Gaps = 42/374 (11%)
Query: 43 VQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWD 102
+ L++ + V ++R S+ W +LP G + ++ +YYR + EL++ NITP+V L+
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 103 MPT---PFMDLR--GWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGAD 157
P P + R W NP F +YAR+ F G +K W T+NEP+
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT----- 696
Query: 158 YFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNF 217
Y H L+ +HA A+H+Y ++F+ Q GK+ I L A P P +
Sbjct: 697 -------------YSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQ 743
Query: 218 QDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTA 277
+D L+ F A PIF + GDYP +R +N + LPYFT
Sbjct: 744 KDKEVAERVLE-----FDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTE 791
Query: 278 EEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLS 337
+E K+I+G+ DF L+HYTT L+ SE E I D+ +V+ D W + ++
Sbjct: 792 DEKKLIQGTFDFLALSHYTTILVD-SEKED--PIKYNDY-LEVQEMTDITWLNSPSQ-VA 846
Query: 338 VYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYD-RISYFNKYLYQLLLAIHED 396
V P G RK+LN++ YG ++P+ + NG+ D +D R+ Y Y+ + L A D
Sbjct: 847 VVPWGLRKVLNWLKFKYG-DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILD 905
Query: 397 NCNIIGYFAWTLMD 410
N+ GYFA++ D
Sbjct: 906 GINLCGYFAYSFND 919
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 235 bits (575), Expect = 2e-61
Identities = 154/434 (35%), Positives = 217/434 (50%), Gaps = 66/434 (15%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSN----------------GDIAADSYHKFKEDVQLIKA 48
+GKG SIWDT+ H HP P S GD+A+DSY+ D + ++
Sbjct: 83 HGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRE 141
Query: 49 LGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFM 108
LGV +YR SISW R+LPNG++ + +G RYYR L E L + + P+VTL+HWD+P
Sbjct: 142 LGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQ 201
Query: 109 D-LRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHG 167
D GW N + D+F DYA + F +G +K W TI+ P+ + GY AP I+
Sbjct: 202 DAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSP 261
Query: 168 VGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYL 227
YL AH L+L+HAK +HLY F+P Q G+V I L + +PR D S
Sbjct: 262 RLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHW---INPRRMTD----HSIK 314
Query: 228 QIHK-LHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGS 286
+ K L F +A P+F +GDYP ++ NN+S S LP FT E K I+G+
Sbjct: 315 ECQKSLDFVLGWFAKPVF-IDGDYPESMK---NNLS-------SILPDFTESEKKFIKGT 363
Query: 287 SDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKL 346
+DFF L P + S +D + R + P+ R+L
Sbjct: 364 ADFFAL------CFGP-----TLSFQLLDPHMKFRQLESPN---------------LRQL 397
Query: 347 LNYVSDNYGREIPIIVTENGVGDKGQLK--DYDRISYFNKYLYQLLLAIHEDNCNIIGYF 404
L+++ + I + ENG G K D + Y K++ + L AI D ++IGY
Sbjct: 398 LSWIDLEFNHP-QIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYT 456
Query: 405 AWTLMDDFEWSDGY 418
AW+LMD FEW GY
Sbjct: 457 AWSLMDGFEWHRGY 470
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 235 bits (575), Expect = 2e-61
Identities = 154/434 (35%), Positives = 217/434 (50%), Gaps = 66/434 (15%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSN----------------GDIAADSYHKFKEDVQLIKA 48
+GKG SIWDT+ H HP P S GD+A+DSY+ D + ++
Sbjct: 83 HGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRE 141
Query: 49 LGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFM 108
LGV +YR SISW R+LPNG++ + +G RYYR L E L + + P+VTL+HWD+P
Sbjct: 142 LGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQ 201
Query: 109 D-LRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHG 167
D GW N + D+F DYA + F +G +K W TI+ P+ + GY AP I+
Sbjct: 202 DAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSP 261
Query: 168 VGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYL 227
YL AH L+L+HAK +HLY F+P Q G+V I L + +PR D S
Sbjct: 262 RLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHW---INPRRMTD----HSIK 314
Query: 228 QIHK-LHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGS 286
+ K L F +A P+F +GDYP ++ NN+S S LP FT E K I+G+
Sbjct: 315 ECQKSLDFVLGWFAKPVF-IDGDYPESMK---NNLS-------SILPDFTESEKKFIKGT 363
Query: 287 SDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKL 346
+DFF L P + S +D + R + P+ R+L
Sbjct: 364 ADFFAL------CFGP-----TLSFQLLDPHMKFRQLESPN---------------LRQL 397
Query: 347 LNYVSDNYGREIPIIVTENGVGDKGQLK--DYDRISYFNKYLYQLLLAIHEDNCNIIGYF 404
L+++ + I + ENG G K D + Y K++ + L AI D ++IGY
Sbjct: 398 LSWIDLEFNHP-QIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYT 456
Query: 405 AWTLMDDFEWSDGY 418
AW+LMD FEW GY
Sbjct: 457 AWSLMDGFEWHRGY 470
Score = 166 bits (404), Expect = 1e-40
Identities = 118/374 (31%), Positives = 183/374 (48%), Gaps = 42/374 (11%)
Query: 43 VQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWD 102
+ L++ + V ++R S+ W +LP G + ++ +YYR + EL++ NITP+V L+
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 103 MPT---PFMDLR--GWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGAD 157
P P + R W NP F +YAR+ F G +K W T+NEP+
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT----- 696
Query: 158 YFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNF 217
Y H L+ +HA A+H+Y ++F+ Q GK+ I L A P P +
Sbjct: 697 -------------YSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQ 743
Query: 218 QDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTA 277
+D L+ F A PIF + GDYP +R +N + LPYFT
Sbjct: 744 KDKEVAERVLE-----FDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTE 791
Query: 278 EEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLS 337
+E K+I+G+ DF L+HYTT L+ SE E I D+ +V+ D W + ++
Sbjct: 792 DEKKLIQGTFDFLALSHYTTILVD-SEKED--PIKYNDY-LEVQEMTDITWLNSPSQ-VA 846
Query: 338 VYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYD-RISYFNKYLYQLLLAIHED 396
V P G RK+LN++ YG ++P+ + NG+ D +D R+ Y Y+ + L A D
Sbjct: 847 VVPWGLRKVLNWLKFKYG-DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILD 905
Query: 397 NCNIIGYFAWTLMD 410
N+ GYFA++ D
Sbjct: 906 GINLCGYFAYSFND 919
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 235 bits (575), Expect = 2e-61
Identities = 154/434 (35%), Positives = 217/434 (50%), Gaps = 66/434 (15%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSN----------------GDIAADSYHKFKEDVQLIKA 48
+GKG SIWDT+ H HP P S GD+A+DSY+ D + ++
Sbjct: 83 HGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRE 141
Query: 49 LGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFM 108
LGV +YR SISW R+LPNG++ + +G RYYR L E L + + P+VTL+HWD+P
Sbjct: 142 LGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQ 201
Query: 109 D-LRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHG 167
D GW N + D+F DYA + F +G +K W TI+ P+ + GY AP I+
Sbjct: 202 DAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSP 261
Query: 168 VGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYL 227
YL AH L+L+HAK +HLY F+P Q G+V I L + +PR D S
Sbjct: 262 RLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHW---INPRRMTD----HSIK 314
Query: 228 QIHK-LHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGS 286
+ K L F +A P+F +GDYP ++ NN+S S LP FT E K I+G+
Sbjct: 315 ECQKSLDFVLGWFAKPVF-IDGDYPESMK---NNLS-------SILPDFTESEKKFIKGT 363
Query: 287 SDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKL 346
+DFF L P + S +D + R + P+ R+L
Sbjct: 364 ADFFAL------CFGP-----TLSFQLLDPHMKFRQLESPN---------------LRQL 397
Query: 347 LNYVSDNYGREIPIIVTENGVGDKGQLK--DYDRISYFNKYLYQLLLAIHEDNCNIIGYF 404
L+++ + I + ENG G K D + Y K++ + L AI D ++IGY
Sbjct: 398 LSWIDLEFNHP-QIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYT 456
Query: 405 AWTLMDDFEWSDGY 418
AW+LMD FEW GY
Sbjct: 457 AWSLMDGFEWHRGY 470
Score = 166 bits (404), Expect = 1e-40
Identities = 118/374 (31%), Positives = 183/374 (48%), Gaps = 42/374 (11%)
Query: 43 VQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWD 102
+ L++ + V ++R S+ W +LP G + ++ +YYR + EL++ NITP+V L+
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 103 MPT---PFMDLR--GWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGAD 157
P P + R W NP F +YAR+ F G +K W T+NEP+
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT----- 696
Query: 158 YFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNF 217
Y H L+ +HA A+H+Y ++F+ Q GK+ I L A P P +
Sbjct: 697 -------------YSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQ 743
Query: 218 QDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTA 277
+D L+ F A PIF + GDYP +R +N + LPYFT
Sbjct: 744 KDKEVAERVLE-----FDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTE 791
Query: 278 EEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLS 337
+E K+I+G+ DF L+HYTT L+ SE E I D+ +V+ D W + ++
Sbjct: 792 DEKKLIQGTFDFLALSHYTTILVD-SEKED--PIKYNDY-LEVQEMTDITWLNSPSQ-VA 846
Query: 338 VYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYD-RISYFNKYLYQLLLAIHED 396
V P G RK+LN++ YG ++P+ + NG+ D +D R+ Y Y+ + L A D
Sbjct: 847 VVPWGLRKVLNWLKFKYG-DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILD 905
Query: 397 NCNIIGYFAWTLMD 410
N+ GYFA++ D
Sbjct: 906 GINLCGYFAYSFND 919
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 221 bits (541), Expect = 3e-57
Identities = 135/417 (32%), Positives = 210/417 (50%), Gaps = 50/417 (11%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWD ++H H + +NG ++DSY ++D+ + +GV +Y+ SISWPRL
Sbjct: 103 DGKGPSIWDHFIHTHLKNV-SSTNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLF 159
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMD-LRGWNNPVIVDYFV 123
P+G + G +YY L + L+ NI PIVTL+HWD+P + GW N I+D F
Sbjct: 160 PDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFN 219
Query: 124 DYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAK 183
DYA F ++GD +K W TI+ P+ + GYG AP K + Y H LI +H+K
Sbjct: 220 DYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSK 279
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
+H Y F+PHQKG + ITL + P N D+ + + + L + +A+PI
Sbjct: 280 VWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSM-VSVLGW----FANPI 334
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
+GDYP +R+++ ++ LP F+ E +RG++DFF + P+
Sbjct: 335 -HGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGTADFF------AFSFGPN 377
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ M + + + + +W K L Y N R I++
Sbjct: 378 NFKPLNTMAKMGQNVSLNLREALNWIK----------------LEY---NNPR---ILIA 415
Query: 364 ENGVGDKGQLKDYDRISYF--NKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENG ++K D + + +L Q+L AI D + GY AW+L+D FEW D Y
Sbjct: 416 ENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAY 472
Score = 195 bits (475), Expect = 3e-49
Identities = 121/377 (32%), Positives = 193/377 (51%), Gaps = 28/377 (7%)
Query: 40 KEDVQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLF 99
K+ ++++ + V +YR ++ W +LP G + ++ RYYR + E LK I+ +VTL+
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 100 -----HWDMPTPFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGY 154
H +P P + GW NP + F YA + F GD++K W TINEP++
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 155 GADYFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDP 214
+ G Y AH L+++HA A+ LY+++F+P Q+G V ++L A P +P
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANP 752
Query: 215 RNFQDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPY 274
A +LQ F+ +A P+F GDYP +R+ I + +G + S LP
Sbjct: 753 YADSHWRAAERFLQ-----FEIAWFAEPLFKT-GDYPAAMREYIASKH-RRGLSSSALPR 805
Query: 275 FTAEEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTD 334
T E ++++G+ DF LNH+TT + ++ S D D ++ QD T
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS----RYDSDRDIQFLQDITRLSSPTR 861
Query: 335 WLSVYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYDRISYFNKYLYQLLLAIH 394
L+V P G RKLL +V NYG ++ I +T +G+ D+ D R Y KYL ++L A
Sbjct: 862 -LAVIPWGVRKLLRWVRRNYG-DMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYL 919
Query: 395 EDNCNIIGYFAWTLMDD 411
D I GY+A+ L ++
Sbjct: 920 IDKVRIKGYYAFKLAEE 936
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 221 bits (541), Expect = 3e-57
Identities = 135/417 (32%), Positives = 210/417 (50%), Gaps = 50/417 (11%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWD ++H H + +NG ++DSY ++D+ + +GV +Y+ SISWPRL
Sbjct: 103 DGKGPSIWDHFIHTHLKNV-SSTNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLF 159
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMD-LRGWNNPVIVDYFV 123
P+G + G +YY L + L+ NI PIVTL+HWD+P + GW N I+D F
Sbjct: 160 PDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFN 219
Query: 124 DYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAK 183
DYA F ++GD +K W TI+ P+ + GYG AP K + Y H LI +H+K
Sbjct: 220 DYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSK 279
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
+H Y F+PHQKG + ITL + P N D+ + + + L + +A+PI
Sbjct: 280 VWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSM-VSVLGW----FANPI 334
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
+GDYP +R+++ ++ LP F+ E +RG++DFF + P+
Sbjct: 335 -HGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGTADFF------AFSFGPN 377
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ M + + + + +W K L Y N R I++
Sbjct: 378 NFKPLNTMAKMGQNVSLNLREALNWIK----------------LEY---NNPR---ILIA 415
Query: 364 ENGVGDKGQLKDYDRISYF--NKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENG ++K D + + +L Q+L AI D + GY AW+L+D FEW D Y
Sbjct: 416 ENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAY 472
Score = 195 bits (475), Expect = 3e-49
Identities = 121/377 (32%), Positives = 193/377 (51%), Gaps = 28/377 (7%)
Query: 40 KEDVQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLF 99
K+ ++++ + V +YR ++ W +LP G + ++ RYYR + E LK I+ +VTL+
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 100 -----HWDMPTPFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGY 154
H +P P + GW NP + F YA + F GD++K W TINEP++
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 155 GADYFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDP 214
+ G Y AH L+++HA A+ LY+++F+P Q+G V ++L A P +P
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANP 752
Query: 215 RNFQDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPY 274
A +LQ F+ +A P+F GDYP +R+ I + +G + S LP
Sbjct: 753 YADSHWRAAERFLQ-----FEIAWFAEPLFKT-GDYPAAMREYIASKH-RRGLSSSALPR 805
Query: 275 FTAEEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTD 334
T E ++++G+ DF LNH+TT + ++ S D D ++ QD T
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS----RYDSDRDIQFLQDITRLSSPTR 861
Query: 335 WLSVYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYDRISYFNKYLYQLLLAIH 394
L+V P G RKLL +V NYG ++ I +T +G+ D+ D R Y KYL ++L A
Sbjct: 862 -LAVIPWGVRKLLRWVRRNYG-DMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYL 919
Query: 395 EDNCNIIGYFAWTLMDD 411
D I GY+A+ L ++
Sbjct: 920 IDKVRIKGYYAFKLAEE 936
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 221 bits (541), Expect = 3e-57
Identities = 135/417 (32%), Positives = 210/417 (50%), Gaps = 50/417 (11%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPRLL 64
+GKG SIWD ++H H + +NG ++DSY ++D+ + +GV +Y+ SISWPRL
Sbjct: 103 DGKGPSIWDHFIHTHLKNV-SSTNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLF 159
Query: 65 PNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFMD-LRGWNNPVIVDYFV 123
P+G + G +YY L + L+ NI PIVTL+HWD+P + GW N I+D F
Sbjct: 160 PDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFN 219
Query: 124 DYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHGVGEYLCAHYLILSHAK 183
DYA F ++GD +K W TI+ P+ + GYG AP K + Y H LI +H+K
Sbjct: 220 DYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSK 279
Query: 184 AYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPI 243
+H Y F+PHQKG + ITL + P N D+ + + + L + +A+PI
Sbjct: 280 VWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSM-VSVLGW----FANPI 334
Query: 244 FSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTYLMSPS 303
+GDYP +R+++ ++ LP F+ E +RG++DFF + P+
Sbjct: 335 -HGDGDYPEGMRKKLFSV----------LPIFSEAEKHEMRGTADFF------AFSFGPN 377
Query: 304 EMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVT 363
+ ++ M + + + + +W K L Y N R I++
Sbjct: 378 NFKPLNTMAKMGQNVSLNLREALNWIK----------------LEY---NNPR---ILIA 415
Query: 364 ENGVGDKGQLKDYDRISYF--NKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSDGY 418
ENG ++K D + + +L Q+L AI D + GY AW+L+D FEW D Y
Sbjct: 416 ENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAY 472
Score = 195 bits (475), Expect = 3e-49
Identities = 121/377 (32%), Positives = 193/377 (51%), Gaps = 28/377 (7%)
Query: 40 KEDVQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLF 99
K+ ++++ + V +YR ++ W +LP G + ++ RYYR + E LK I+ +VTL+
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 100 -----HWDMPTPFMDLRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGY 154
H +P P + GW NP + F YA + F GD++K W TINEP++
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 155 GADYFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDP 214
+ G Y AH L+++HA A+ LY+++F+P Q+G V ++L A P +P
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANP 752
Query: 215 RNFQDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPY 274
A +LQ F+ +A P+F GDYP +R+ I + +G + S LP
Sbjct: 753 YADSHWRAAERFLQ-----FEIAWFAEPLFKT-GDYPAAMREYIASKH-RRGLSSSALPR 805
Query: 275 FTAEEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTD 334
T E ++++G+ DF LNH+TT + ++ S D D ++ QD T
Sbjct: 806 LTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS----RYDSDRDIQFLQDITRLSSPTR 861
Query: 335 WLSVYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYDRISYFNKYLYQLLLAIH 394
L+V P G RKLL +V NYG ++ I +T +G+ D+ D R Y KYL ++L A
Sbjct: 862 -LAVIPWGVRKLLRWVRRNYG-DMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYL 919
Query: 395 EDNCNIIGYFAWTLMDD 411
D I GY+A+ L ++
Sbjct: 920 IDKVRIKGYYAFKLAEE 936
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 166 bits (404), Expect = 1e-40
Identities = 118/374 (31%), Positives = 183/374 (48%), Gaps = 42/374 (11%)
Query: 43 VQLIKALGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWD 102
+ L++ + V ++R S+ W +LP G + ++ +YYR + EL++ NITP+V L+
Sbjct: 309 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 368
Query: 103 MPT---PFMDLR--GWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGAD 157
P P + R W NP F +YAR+ F G +K W T+NEP+
Sbjct: 369 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT----- 423
Query: 158 YFAPAIKSHGVGEYLCAHYLILSHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNF 217
Y H L+ +HA A+H+Y ++F+ Q GK+ I L A P P +
Sbjct: 424 -------------YSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQ 470
Query: 218 QDVLAVRSYLQIHKLHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTA 277
+D L+ F A PIF + GDYP +R +N + LPYFT
Sbjct: 471 KDKEVAERVLE-----FDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTE 518
Query: 278 EEVKIIRGSSDFFGLNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLS 337
+E K+I+G+ DF L+HYTT L+ SE E I D+ +V+ D W + ++
Sbjct: 519 DEKKLIQGTFDFLALSHYTTILVD-SEKED--PIKYNDY-LEVQEMTDITWLNSPSQ-VA 573
Query: 338 VYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQLKDYD-RISYFNKYLYQLLLAIHED 396
V P G RK+LN++ YG ++P+ + NG+ D +D R+ Y Y+ + L A D
Sbjct: 574 VVPWGLRKVLNWLKFKYG-DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILD 632
Query: 397 NCNIIGYFAWTLMD 410
N+ GYFA++ D
Sbjct: 633 GINLCGYFAYSFND 646
Score = 86.6 bits (205), Expect = 1e-16
Identities = 77/242 (31%), Positives = 111/242 (45%), Gaps = 48/242 (19%)
Query: 180 SHAKAYHLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHK-LHFQFDL 238
+HAK +HLY F+P Q G+V I L + +PR D S + K L F
Sbjct: 1 AHAKVWHLYNTSFRPTQGGQVSIALSSHW---INPRRMTD----HSIKECQKSLDFVLGW 53
Query: 239 YAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFGLNHYTTY 298
+A P+F +GDYP ++ NN+S S LP FT E K I+G++DFF L
Sbjct: 54 FAKPVF-IDGDYPESMK---NNLS-------SILPDFTESEKKFIKGTADFFAL------ 96
Query: 299 LMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREI 358
P + S +D + R + P+ R+LL+++ +
Sbjct: 97 CFGP-----TLSFQLLDPHMKFRQLESPN---------------LRQLLSWIDLEFNHP- 135
Query: 359 PIIVTENGVGDKGQLK--DYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDDFEWSD 416
I + ENG G K D + Y K++ + L AI D ++IGY AW+LMD FEW
Sbjct: 136 QIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHR 195
Query: 417 GY 418
GY
Sbjct: 196 GY 197
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 153 bits (370), Expect = 1e-36
Identities = 77/192 (40%), Positives = 106/192 (55%), Gaps = 18/192 (9%)
Query: 5 NGKGESIWDTYVHEHPEYTPDKSN----------------GDIAADSYHKFKEDVQLIKA 48
+GKG SIWDT+ H HP P S GD+A+DSY+ D + ++
Sbjct: 83 HGKGASIWDTFTH-HPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRE 141
Query: 49 LGVKYYRLSISWPRLLPNGTSNNISTDGARYYRNLFEELLKANITPIVTLFHWDMPTPFM 108
LGV +YR SISW R+LPNG++ + +G RYYR L E L + + P+VTL+HWD+P
Sbjct: 142 LGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQ 201
Query: 109 D-LRGWNNPVIVDYFVDYARVAFNLYGDIIKTWTTINEPHQHCYQGYGADYFAPAIKSHG 167
D GW N + D+F DYA + F +G +K W TI+ P+ + GY AP I+
Sbjct: 202 DAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSP 261
Query: 168 VGEYLCAHYLIL 179
YL AH L+L
Sbjct: 262 RLGYLVAHNLLL 273
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 93.5 bits (222), Expect = 1e-18
Identities = 61/180 (33%), Positives = 94/180 (52%), Gaps = 8/180 (4%)
Query: 232 LHFQFDLYAHPIFSAEGDYPTFVRQRINNMSLAQGFARSRLPYFTAEEVKIIRGSSDFFG 291
L F+ +A P+F GDYP +R+ I + +G + S LP T E ++++G+ DF
Sbjct: 26 LQFEIAWFAEPLFKT-GDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCA 83
Query: 292 LNHYTTYLMSPSEMEFSWSIPSMDHDAQVRMEQDPHWEKPGTDWLSVYPEGFRKLLNYVS 351
LNH+TT + ++ S D D ++ QD T L+V P G RKLL +V
Sbjct: 84 LNHFTTRFVMHEQLAGS----RYDSDRDIQFLQDITRLSSPTR-LAVIPWGVRKLLRWVR 138
Query: 352 DNYGREIPIIVTENGVGDKGQLKDYDRISYFNKYLYQLLLAIHEDNCNIIGYFAWTLMDD 411
NYG ++ I +T +G+ D+ D R Y KYL ++L A D I GY+A+ L ++
Sbjct: 139 RNYG-DMDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEE 197
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 74.5 bits (175), Expect = 6e-13
Identities = 31/71 (43%), Positives = 47/71 (66%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNIS 73
LLP+GT+ I+
Sbjct: 83 LLPDGTTGFIN 93
Score = 37.1 bits (82), Expect = 0.12
Identities = 14/27 (51%), Positives = 19/27 (70%)
Query: 392 AIHEDNCNIIGYFAWTLMDDFEWSDGY 418
AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGY 122
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 74.5 bits (175), Expect = 6e-13
Identities = 31/71 (43%), Positives = 47/71 (66%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNIS 73
LLP+GT+ I+
Sbjct: 83 LLPDGTTGFIN 93
Score = 37.1 bits (82), Expect = 0.12
Identities = 14/27 (51%), Positives = 19/27 (70%)
Query: 392 AIHEDNCNIIGYFAWTLMDDFEWSDGY 418
AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGY 122
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 73.7 bits (173), Expect = 1e-12
Identities = 31/71 (43%), Positives = 47/71 (66%)
Query: 3 NVNGKGESIWDTYVHEHPEYTPDKSNGDIAADSYHKFKEDVQLIKALGVKYYRLSISWPR 62
+ +GKG +WDT+ H+ E GD+A SY ++ED++ IK LG+ +YR S+SW R
Sbjct: 23 DADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSR 82
Query: 63 LLPNGTSNNIS 73
LLP+GT+ I+
Sbjct: 83 LLPDGTTGFIN 93
Score = 37.1 bits (82), Expect = 0.12
Identities = 14/27 (51%), Positives = 19/27 (70%)
Query: 392 AIHEDNCNIIGYFAWTLMDDFEWSDGY 418
AI D N+ Y AW+L+D+FEW+ GY
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGY 122
>AB002340-1|BAA20800.3| 2467|Homo sapiens KIAA0342 protein protein.
Length = 2467
Score = 33.5 bits (73), Expect = 1.4
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 337 SVYPEGFRKLLNYVSDNYGREIPIIVTENGVGDKGQ 372
S YPE F KLL+ DNY RE+ + +E +G+
Sbjct: 1839 SNYPEEFEKLLHQEEDNYNRELKALESEKDERGRGR 1874
>Y10523-1|CAA71535.1| 1336|Homo sapiens immunoglobulin-like
domain-containing 1 protein.
Length = 1336
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1114 GYRADFWMPAVRGEDSGIYSCVYYL 1138
>X83957-1|CAA58788.1| 6669|Homo sapiens nebulin protein.
Length = 6669
Score = 31.1 bits (67), Expect = 7.6
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 29 GDIAADSYHKFKEDVQLIKALGVKYYRL-SISWPRLLPNGTSNNISTDGARYYRNLFEEL 87
GDI +D K+KED+Q++K G Y + R L SN + TD AR R+ ++ +
Sbjct: 5083 GDITSDI--KYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKAREMRDKYKVV 5140
Query: 88 L 88
L
Sbjct: 5141 L 5141
>U35637-1|AAB02622.1| 3007|Homo sapiens nebulin protein.
Length = 3007
Score = 31.1 bits (67), Expect = 7.6
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 29 GDIAADSYHKFKEDVQLIKALGVKYYRL-SISWPRLLPNGTSNNISTDGARYYRNLFEEL 87
GDI +D K+KED+Q++K G Y + R L SN + TD AR R+ ++ +
Sbjct: 1514 GDITSDI--KYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVV 1571
Query: 88 L 88
L
Sbjct: 1572 L 1572
>BT006631-1|AAP35277.1| 342|Homo sapiens sorting nexin 15 protein.
Length = 342
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>BC063884-1|AAH63884.1| 1336|Homo sapiens immunoglobulin superfamily,
member 1 protein.
Length = 1336
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1114 GYRADFWMPAVRGEDSGIYSCVYYL 1138
>BC033798-1|AAH33798.1| 430|Homo sapiens spermatogenic leucine
zipper 1 protein.
Length = 430
Score = 31.1 bits (67), Expect = 7.6
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 322 MEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVTE--NGVGDKGQLKDYDRI 379
+++ HW K T+ LS + ++K +S+ G T+ N V K +L++ +
Sbjct: 251 LQEAEHWSKQHTE-LSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKK 309
Query: 380 SYFNKYLYQLLLAIHEDNCNII 401
+ Y QL+ A+ E+ C I+
Sbjct: 310 LSHDTYSLQLMAALLENECQIL 331
>BC014520-1|AAH14520.1| 342|Homo sapiens sorting nexin 15 protein.
Length = 342
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>BC012767-1|AAH12767.1| 342|Homo sapiens sorting nexin 15 protein.
Length = 342
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>BC009897-1|AAH09897.1| 342|Homo sapiens sorting nexin 15 protein.
Length = 342
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>AL590806-2|CAI41249.1| 1336|Homo sapiens immunoglobulin superfamily,
member 1 protein.
Length = 1336
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1114 GYRADFWMPAVRGEDSGIYSCVYYL 1138
>AL590806-1|CAI41248.1| 1327|Homo sapiens immunoglobulin superfamily,
member 1 protein.
Length = 1327
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1105 GYRADFWMPAVRGEDSGIYSCVYYL 1129
>AK098575-1|BAC05340.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ25709 fis, clone TST04944. ).
Length = 382
Score = 31.1 bits (67), Expect = 7.6
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 322 MEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVTE--NGVGDKGQLKDYDRI 379
+++ HW K T+ LS + ++K +S+ G T+ N V K +L++ +
Sbjct: 203 LQEAEHWSKQHTE-LSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKK 261
Query: 380 SYFNKYLYQLLLAIHEDNCNII 401
+ Y QL+ A+ E+ C I+
Sbjct: 262 LSHDTYSLQLMAALLENECQIL 283
>AF333098-1|AAK17995.1| 430|Homo sapiens testis-specific protein
NYD-TSP1 protein.
Length = 430
Score = 31.1 bits (67), Expect = 7.6
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 3/82 (3%)
Query: 322 MEQDPHWEKPGTDWLSVYPEGFRKLLNYVSDNYGREIPIIVTE--NGVGDKGQLKDYDRI 379
+++ HW K T+ LS + ++K +S+ G T+ N V K +L++ +
Sbjct: 251 LQEAEHWSKQHTE-LSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKPELEEQVKK 309
Query: 380 SYFNKYLYQLLLAIHEDNCNII 401
+ Y QL+ A+ E+ C I+
Sbjct: 310 LSHDTYSLQLMAALLENECQIL 331
>AF175268-1|AAF89956.1| 255|Homo sapiens sorting nexin 15A protein.
Length = 255
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>AF175267-1|AAF89955.1| 342|Homo sapiens sorting nexin 15 protein.
Length = 342
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>AF034198-1|AAC52057.1| 1327|Homo sapiens IGSF1 protein.
Length = 1327
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1105 GYRADFWMPAVRGEDSGIYSCVYYL 1129
>AF001435-1|AAB81205.1| 152|Homo sapiens unknown protein.
Length = 152
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 12 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 71
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 72 RLEEFPAFPRAQV 84
>AC009497-1|AAY14651.1| 2802|Homo sapiens unknown protein.
Length = 2802
Score = 31.1 bits (67), Expect = 7.6
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 29 GDIAADSYHKFKEDVQLIKALGVKYYRL-SISWPRLLPNGTSNNISTDGARYYRNLFEEL 87
GDI +D K+KED+Q++K G Y + R L SN + TD AR R+ ++ +
Sbjct: 1216 GDITSDI--KYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVV 1273
Query: 88 L 88
L
Sbjct: 1274 L 1274
>AB209439-1|BAD92676.1| 267|Homo sapiens sorting nexin 15 isoform B
variant protein.
Length = 267
Score = 31.1 bits (67), Expect = 7.6
Identities = 17/73 (23%), Positives = 30/73 (41%)
Query: 186 HLYEKEFKPHQKGKVGITLDAFMGIPKDPRNFQDVLAVRSYLQIHKLHFQFDLYAHPIFS 245
H + + H KG + A KDP + ++V+ + Y KLH +F
Sbjct: 11 HYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFR 70
Query: 246 AEGDYPTFVRQRI 258
++P F R ++
Sbjct: 71 RLEEFPAFPRAQV 83
>AB002362-1|BAA20819.2| 1437|Homo sapiens KIAA0364 protein.
Length = 1437
Score = 31.1 bits (67), Expect = 7.6
Identities = 11/25 (44%), Positives = 16/25 (64%)
Query: 153 GYGADYFAPAIKSHGVGEYLCAHYL 177
GY AD++ PA++ G Y C +YL
Sbjct: 1215 GYRADFWMPAVRGEDSGIYSCVYYL 1239
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.140 0.447
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,568,509
Number of Sequences: 224733
Number of extensions: 3168449
Number of successful extensions: 4470
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 4248
Number of HSP's gapped (non-prelim): 95
length of query: 419
length of database: 73,234,838
effective HSP length: 92
effective length of query: 327
effective length of database: 52,559,402
effective search space: 17186924454
effective search space used: 17186924454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)
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