Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002431-TA|BGIBMGA002431-PA|IPR007371|Thiamin
pyrophosphokinase, catalytic region, IPR007373|Thiamin
pyrophosphokinase, vitamin B1-binding region
(128 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC068460-1|AAH68460.1| 243|Homo sapiens thiamin pyrophosphokina... 52 7e-07
BC014552-1|AAH14552.2| 233|Homo sapiens TPK1 protein protein. 52 7e-07
AY206415-1|AAO38775.1| 243|Homo sapiens placental protein 20 pr... 52 7e-07
AF297710-1|AAK01351.1| 243|Homo sapiens thiamine pyrophosphokin... 52 7e-07
AB028138-1|BAB20326.1| 243|Homo sapiens thiamin pyrophosphokina... 52 7e-07
AK128661-1|BAC87556.1| 189|Homo sapiens protein ( Homo sapiens ... 46 4e-05
AK026374-1|BAB15465.1| 137|Homo sapiens protein ( Homo sapiens ... 46 4e-05
Y16787-1|CAA76383.1| 416|Homo sapiens type I hair keratin 1 pro... 29 5.9
BC114468-1|AAI14469.1| 416|Homo sapiens keratin 31 protein. 29 5.9
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 28 7.9
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 28 7.9
>BC068460-1|AAH68460.1| 243|Homo sapiens thiamin
pyrophosphokinase 1 protein.
Length = 243
Score = 51.6 bits (118), Expect = 7e-07
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 6 SLRYAVLILNRPISQEEAFMKNFWEKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDL 65
+L+Y ++ILN+P+ + ++ W KA LR DGGA R E + +P+
Sbjct: 16 NLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDIT-----EGERESFLPEF 67
Query: 66 ITGDFDSITEETLQKYKKKG 85
I GDFDSI E + Y KG
Sbjct: 68 INGDFDSIRPEVREYYATKG 87
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 206 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 243
>BC014552-1|AAH14552.2| 233|Homo sapiens TPK1 protein protein.
Length = 233
Score = 51.6 bits (118), Expect = 7e-07
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 6 SLRYAVLILNRPISQEEAFMKNFWEKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDL 65
+L+Y ++ILN+P+ + ++ W KA LR DGGA R E + +P+
Sbjct: 6 NLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDIT-----EGERESFLPEF 57
Query: 66 ITGDFDSITEETLQKYKKKG 85
I GDFDSI E + Y KG
Sbjct: 58 INGDFDSIRPEVREYYATKG 77
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 196 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 233
>AY206415-1|AAO38775.1| 243|Homo sapiens placental protein 20
protein.
Length = 243
Score = 51.6 bits (118), Expect = 7e-07
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 6 SLRYAVLILNRPISQEEAFMKNFWEKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDL 65
+L+Y ++ILN+P+ + ++ W KA LR DGGA R E + +P+
Sbjct: 16 NLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDIT-----EGERESFLPEF 67
Query: 66 ITGDFDSITEETLQKYKKKG 85
I GDFDSI E + Y KG
Sbjct: 68 INGDFDSIRPEVREYYATKG 87
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 206 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 243
>AF297710-1|AAK01351.1| 243|Homo sapiens thiamine
pyrophosphokinase protein.
Length = 243
Score = 51.6 bits (118), Expect = 7e-07
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 6 SLRYAVLILNRPISQEEAFMKNFWEKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDL 65
+L+Y ++ILN+P+ + ++ W KA LR DGGA R E + +P+
Sbjct: 16 NLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDIT-----EGERESFLPEF 67
Query: 66 ITGDFDSITEETLQKYKKKG 85
I GDFDSI E + Y KG
Sbjct: 68 INGDFDSIRPEVREYYATKG 87
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 206 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 243
>AB028138-1|BAB20326.1| 243|Homo sapiens thiamin
pyrophosphokinase protein.
Length = 243
Score = 51.6 bits (118), Expect = 7e-07
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 6 SLRYAVLILNRPISQEEAFMKNFWEKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDL 65
+L+Y ++ILN+P+ + ++ W KA LR DGGA R E + +P+
Sbjct: 16 NLKYCLVILNQPLDN---YFRHLWNKALLRACADGGANRLYDIT-----EGERESFLPEF 67
Query: 66 ITGDFDSITEETLQKYKKKG 85
I GDFDSI E + Y KG
Sbjct: 68 INGDFDSIRPEVREYYATKG 87
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 206 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 243
>AK128661-1|BAC87556.1| 189|Homo sapiens protein ( Homo sapiens
cDNA FLJ46821 fis, clone TSTOM2002611, moderately
similar to Mus musculus thiamin pyrophosphokinase
(Tpk1). ).
Length = 189
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 152 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 189
Score = 32.7 bits (71), Expect = 0.36
Identities = 14/30 (46%), Positives = 18/30 (60%)
Query: 56 ISNKMKIPDLITGDFDSITEETLQKYKKKG 85
I N+ +P+ I GDFDSI E + Y KG
Sbjct: 53 IGNESFLPEFINGDFDSIRPEVREYYATKG 82
>AK026374-1|BAB15465.1| 137|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22721 fis, clone HSI14381. ).
Length = 137
Score = 46.0 bits (104), Expect = 4e-05
Identities = 19/38 (50%), Positives = 25/38 (65%)
Query: 87 NQSLKFGELVSTSNAFDGSDTVKIKCSHTILWSMKVPS 124
N L FG LVSTSN +DGS V ++ H +LW+M + S
Sbjct: 100 NDVLAFGTLVSTSNTYDGSGVVTVETDHPLLWTMAIKS 137
>Y16787-1|CAA76383.1| 416|Homo sapiens type I hair keratin 1
protein.
Length = 416
Score = 28.7 bits (61), Expect = 5.9
Identities = 22/71 (30%), Positives = 31/71 (43%)
Query: 30 EKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDLITGDFDSITEETLQKYKKKGYNQS 89
E A L + +D L D F T+ E+S + + I G + E TL K + +S
Sbjct: 123 ENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVES 182
Query: 90 LKFGELVSTSN 100
LK L SN
Sbjct: 183 LKEELLCLKSN 193
>BC114468-1|AAI14469.1| 416|Homo sapiens keratin 31 protein.
Length = 416
Score = 28.7 bits (61), Expect = 5.9
Identities = 22/71 (30%), Positives = 31/71 (43%)
Query: 30 EKATLRITVDGGALRWDQFLTRLPEEISNKMKIPDLITGDFDSITEETLQKYKKKGYNQS 89
E A L + +D L D F T+ E+S + + I G + E TL K + +S
Sbjct: 123 ENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVES 182
Query: 90 LKFGELVSTSN 100
LK L SN
Sbjct: 183 LKEELLCLKSN 193
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 28.3 bits (60), Expect = 7.9
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
Query: 47 QFLTRLP---EEISNKMKIPDLITGDFDSITEETLQKYKKKGYNQSLKFGELVSTSNAFD 103
QFL RLP E +++ PD+ ++TEE + +K+ + G L+ +S +
Sbjct: 436 QFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELE 495
Query: 104 GSDTVKIKCSHTILWSMKVPSLTGE 128
K S I ++ + TGE
Sbjct: 496 ELKAENEKLSSQIT-LLEAQNRTGE 519
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372
protein.
Length = 3225
Score = 28.3 bits (60), Expect = 7.9
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
Query: 47 QFLTRLP---EEISNKMKIPDLITGDFDSITEETLQKYKKKGYNQSLKFGELVSTSNAFD 103
QFL RLP E +++ PD+ ++TEE + +K+ + G L+ +S +
Sbjct: 402 QFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELE 461
Query: 104 GSDTVKIKCSHTILWSMKVPSLTGE 128
K S I ++ + TGE
Sbjct: 462 ELKAENEKLSSQIT-LLEAQNRTGE 485
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.133 0.390
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 18,605,352
Number of Sequences: 224733
Number of extensions: 675987
Number of successful extensions: 1417
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1397
Number of HSP's gapped (non-prelim): 17
length of query: 128
length of database: 73,234,838
effective HSP length: 82
effective length of query: 46
effective length of database: 54,806,732
effective search space: 2521109672
effective search space used: 2521109672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 60 (28.3 bits)
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