Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002418-TA|BGIBMGA002418-PA|IPR014021|Helicase
superfamily 1 and 2 ATP-binding, IPR001650|Helicase, C-terminal,
IPR001098|DNA-directed DNA polymerase, IPR014001|DEAD-like helicases,
N-terminal, IPR010995|Rad51, N-terminal, IPR002298|DNA polymerase A,
IPR011545|DEAD/DEAH box helicase, N-terminal
(1486 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY338826-1|AAR08421.2| 2590|Homo sapiens DNA polymerase theta pr... 700 0.0
AY032677-1|AAK39635.1| 2724|Homo sapiens DNA polymerase theta pr... 697 0.0
AB209867-1|BAD93104.1| 2214|Homo sapiens DNA polymerase theta va... 416 e-115
AF436845-1|AAL85274.1| 1101|Homo sapiens DNA helicase HEL308 pro... 376 e-103
DQ060036-1|AAY43130.1| 900|Homo sapiens polymerase (DNA directe... 195 9e-49
AY136549-1|AAN52116.1| 900|Homo sapiens DNA polymerase N protein. 195 9e-49
AL158068-2|CAM20461.1| 900|Homo sapiens polymerase (DNA directe... 195 9e-49
AL136360-1|CAM16854.1| 900|Homo sapiens polymerase (DNA directe... 195 9e-49
AF044578-1|AAD02338.1| 579|Homo sapiens putative DNA polymerase... 194 2e-48
AF052573-1|AAC33565.1| 1762|Homo sapiens DNA polymerase theta pr... 189 6e-47
AF043628-1|AAD05272.1| 1154|Homo sapiens DNA polymerase eta prot... 189 6e-47
AK023840-1|BAB14698.1| 774|Homo sapiens protein ( Homo sapiens ... 145 1e-33
Z70200-1|CAA94089.1| 1701|Homo sapiens U5 snRNP-specific 200kD p... 144 2e-33
BC112891-1|AAI12892.1| 1887|Homo sapiens Unknown (protein for IM... 144 2e-33
AY572488-1|AAS78571.1| 2136|Homo sapiens 200 kDa U5 snRNP-specif... 144 2e-33
AK024391-1|BAB14906.1| 1811|Homo sapiens protein ( Homo sapiens ... 144 2e-33
AB018331-1|BAA34508.2| 2026|Homo sapiens KIAA0788 protein protein. 144 2e-33
BC065924-1|AAH65924.1| 1821|Homo sapiens ASCC3L1 protein protein. 140 5e-32
AB204867-1|BAF45466.1| 1435|Homo sapiens helicase-like protein H... 126 8e-28
AK131239-1|BAD18421.1| 312|Homo sapiens protein ( Homo sapiens ... 125 1e-27
BC007577-1|AAH07577.1| 1308|Homo sapiens ASCC3L1 protein protein. 122 1e-26
Z86062-1|CAI19454.1| 2193|Homo sapiens RP1-121G13.4 protein. 118 1e-25
AY013288-1|AAG45474.1| 1917|Homo sapiens ASC-1 complex subunit P... 118 1e-25
AL591585-1|CAH73862.1| 2193|Homo sapiens RP1-121G13.4 protein. 118 1e-25
AL356122-1|CAI16190.1| 2193|Homo sapiens RP1-121G13.4 protein. 118 1e-25
AL133338-2|CAI21439.1| 2193|Homo sapiens RP1-121G13.4 protein. 118 1e-25
AL121965-1|CAI19627.1| 2193|Homo sapiens RP1-121G13.4 protein. 118 1e-25
Z48796-1|CAA88733.1| 1246|Homo sapiens helicase protein. 101 3e-20
D29641-1|BAA06124.2| 1046|Homo sapiens KIAA0052 protein protein. 101 3e-20
BC113509-1|AAI13510.1| 1042|Homo sapiens superkiller viralicidic... 101 3e-20
BC104996-1|AAI04997.1| 1042|Homo sapiens superkiller viralicidic... 101 3e-20
BC065258-1|AAH65258.1| 1043|Homo sapiens SKIV2L2 protein protein. 101 3e-20
BC028604-1|AAH28604.3| 1042|Homo sapiens superkiller viralicidic... 101 3e-20
U09877-1|AAB52523.1| 1245|Homo sapiens helicase-like protein pro... 99 6e-20
X98378-1|CAA67024.1| 1246|Homo sapiens SKI2W protein protein. 99 1e-19
CR753822-4|CAM26058.1| 1246|Homo sapiens superkiller viralicidic... 99 1e-19
BX005143-14|CAM25870.1| 1246|Homo sapiens superkiller viralicidi... 99 1e-19
BC015758-1|AAH15758.1| 1246|Homo sapiens superkiller viralicidic... 99 1e-19
AL844853-15|CAI41863.1| 1246|Homo sapiens superkiller viralicidi... 99 1e-19
AL662849-12|CAI17460.1| 1246|Homo sapiens superkiller viralicidi... 99 1e-19
AL645922-13|CAI41730.1| 1246|Homo sapiens superkiller viralicidi... 99 1e-19
AL049547-13|CAB89307.1| 1245|Homo sapiens dJ34F7.7 (superkiller ... 99 1e-19
AF059675-1|AAC78607.1| 1246|Homo sapiens putative RNA helicase S... 99 1e-19
AF019413-6|AAB67978.1| 1246|Homo sapiens helicase protein. 99 1e-19
AJ223948-1|CAA11679.1| 1257|Homo sapiens RNA helicase protein. 86 8e-16
AB209605-1|BAD92842.1| 607|Homo sapiens DJ34F7.7 (Superkiller v... 80 7e-14
BC014669-1|AAH14669.2| 706|Homo sapiens SKIV2L2 protein protein. 79 1e-13
BC038115-1|AAH38115.1| 1712|Homo sapiens hypothetical protein FL... 77 4e-13
BC031779-1|AAH31779.1| 596|Homo sapiens SKIV2L2 protein protein. 76 1e-12
BC132823-1|AAI32824.1| 471|Homo sapiens HFM1 protein protein. 73 6e-12
BC131784-1|AAI31785.1| 595|Homo sapiens ASCC3L1 protein protein. 70 6e-11
AF085356-1|AAD40191.1| 595|Homo sapiens putative RNA helicase p... 70 6e-11
BC026066-1|AAH26066.1| 731|Homo sapiens ASCC3 protein protein. 65 2e-09
D30655-1|BAA06336.1| 407|Homo sapiens eukaryotic initiation fac... 52 2e-05
BT009860-1|AAP88862.1| 407|Homo sapiens eukaryotic translation ... 52 2e-05
BC048105-1|AAH48105.1| 408|Homo sapiens eukaryotic translation ... 52 2e-05
BC016295-1|AAH16295.1| 179|Homo sapiens EIF4A2 protein protein. 52 2e-05
BC015842-1|AAH15842.1| 407|Homo sapiens eukaryotic translation ... 52 2e-05
BC013708-1|AAH13708.1| 407|Homo sapiens eukaryotic translation ... 52 2e-05
BC012547-1|AAH12547.1| 408|Homo sapiens eukaryotic translation ... 52 2e-05
D13748-1|BAA02897.1| 406|Homo sapiens eukaryotic initiation fac... 51 4e-05
BT019881-1|AAV38684.1| 406|Homo sapiens eukaryotic translation ... 51 4e-05
BT019880-1|AAV38683.1| 406|Homo sapiens eukaryotic translation ... 51 4e-05
BC073752-1|AAH73752.1| 406|Homo sapiens eukaryotic translation ... 51 4e-05
BC009585-1|AAH09585.1| 406|Homo sapiens eukaryotic translation ... 51 4e-05
BC006380-1|AAH06380.1| 473|Homo sapiens Unknown (protein for IM... 51 4e-05
BC018637-1|AAH18637.2| 423|Homo sapiens DDX50 protein protein. 47 4e-04
BC000272-1|AAH00272.1| 737|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 47 4e-04
BC000210-1|AAH00210.1| 467|Homo sapiens DDX50 protein protein. 47 4e-04
AL359844-2|CAH72376.1| 737|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 47 4e-04
AL137423-1|CAB70733.1| 399|Homo sapiens hypothetical protein pr... 47 4e-04
AF334103-1|AAK29402.1| 737|Homo sapiens nucleolar protein GU2 p... 47 4e-04
U41387-1|AAB02546.1| 801|Homo sapiens Gu protein protein. 45 0.002
BC008071-1|AAH08071.2| 783|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 45 0.002
AL359844-3|CAH72377.1| 783|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 45 0.002
AF261917-1|AAF78930.2| 715|Homo sapiens RNA helicase II/Gu prot... 45 0.002
AY044431-1|AAK95821.1| 796|Homo sapiens RNA helicase-like prote... 45 0.002
AK022979-1|BAB14343.1| 765|Homo sapiens protein ( Homo sapiens ... 45 0.002
BC130275-1|AAI30276.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 44 0.003
BC126287-1|AAI26288.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 44 0.003
BC016060-1|AAH16060.2| 767|Homo sapiens DDX27 protein protein. 44 0.003
BC011927-1|AAH11927.2| 767|Homo sapiens DDX27 protein protein. 44 0.003
BC009304-1|AAH09304.2| 769|Homo sapiens DDX27 protein protein. 44 0.003
AL357560-1|CAH70236.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 44 0.003
AL049766-1|CAI22427.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 44 0.003
DQ176868-1|AAZ85145.1| 1208|Homo sapiens RecQ protein-like 4 pro... 44 0.004
BC013277-1|AAH13277.2| 652|Homo sapiens RECQL4 protein protein. 44 0.004
BC011602-1|AAH11602.2| 741|Homo sapiens RECQL4 protein protein. 44 0.004
AK223116-1|BAD96836.1| 408|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 44 0.004
AK000603-1|BAA91284.1| 406|Homo sapiens protein ( Homo sapiens ... 44 0.004
AB026546-1|BAA86899.1| 1208|Homo sapiens RECQL4 helicase protein. 44 0.004
AB006532-1|BAA74453.1| 1208|Homo sapiens DNA helicase protein. 44 0.004
D21853-1|BAA04879.2| 412|Homo sapiens KIAA0111 protein. 44 0.005
CR456750-1|CAG33031.1| 411|Homo sapiens DDX48 protein. 44 0.005
BC011151-1|AAH11151.1| 411|Homo sapiens eukaryotic translation ... 44 0.005
BC004386-1|AAH04386.1| 411|Homo sapiens eukaryotic translation ... 44 0.005
BC003662-1|AAH03662.1| 411|Homo sapiens eukaryotic translation ... 44 0.005
AF336851-1|AAK21271.1| 561|Homo sapiens RNA helicase-like prote... 43 0.010
X79538-1|CAA56074.1| 411|Homo sapiens translation initiation fa... 42 0.017
L76937-1|AAC41981.1| 1432|Homo sapiens protein ( Homo sapiens We... 42 0.022
AY818673-1|AAX21098.1| 1432|Homo sapiens Werner syndrome helicas... 42 0.022
AY442327-1|AAR05448.1| 1432|Homo sapiens Werner syndrome protein. 42 0.022
AF181897-1|AAF06162.1| 1432|Homo sapiens WRN protein. 42 0.022
AF091214-1|AAC63361.1| 1432|Homo sapiens WRN protein. 42 0.022
AB209652-1|BAD92889.1| 842|Homo sapiens Werner syndrome protein... 42 0.022
BC041785-1|AAH41785.1| 599|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 41 0.029
BC002366-1|AAH02366.1| 820|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 41 0.029
AK001652-1|BAA91812.1| 491|Homo sapiens protein ( Homo sapiens ... 41 0.029
AJ010840-1|CAA09374.1| 420|Homo sapiens ATP-dependent RNA helic... 41 0.029
AF026402-1|AAB87902.1| 820|Homo sapiens U5 snRNP 100 kD protein... 41 0.029
BC002674-1|AAH02674.1| 483|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 40 0.051
AK223294-1|BAD97014.1| 483|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 40 0.051
AC002985-2|AAB81544.1| 483|Homo sapiens R27090_2 protein. 40 0.051
L36140-1|AAA60261.1| 659|Homo sapiens DNA helicase protein. 39 0.16
D37984-1|BAA07200.1| 649|Homo sapiens DNA helicase Q1 protein. 38 0.21
BT007119-1|AAP35783.1| 649|Homo sapiens RecQ protein-like (DNA ... 38 0.21
BC063440-1|AAH63440.1| 964|Homo sapiens RecQ protein-like 5 pro... 38 0.21
BC016911-1|AAH16911.1| 435|Homo sapiens RECQL5 protein protein. 38 0.21
BC001052-1|AAH01052.1| 649|Homo sapiens RecQ protein-like (DNA ... 38 0.21
AF135183-2|AAD43062.1| 410|Homo sapiens Recq helicase 5 protein. 38 0.21
AF135183-1|AAD43061.1| 435|Homo sapiens Recq helicase 5 protein. 38 0.21
AB042825-1|BAA95954.1| 435|Homo sapiens DNA helicase recQ5 gamm... 38 0.21
AB042824-1|BAA95953.1| 991|Homo sapiens DNA helicase recQ5 beta... 38 0.21
AB042823-1|BAA95952.1| 410|Homo sapiens DNA helicase recQ5 alph... 38 0.21
AB006533-1|BAA74454.1| 410|Homo sapiens DNA helicase protein. 38 0.21
BX641072-1|CAE46035.1| 496|Homo sapiens hypothetical protein pr... 38 0.27
BC015476-1|AAH15476.1| 622|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 38 0.27
AL137455-1|CAB70746.1| 240|Homo sapiens hypothetical protein pr... 38 0.27
AK222598-1|BAD96318.1| 622|Homo sapiens DEAD-box protein abstra... 38 0.27
AK027768-1|BAB55355.1| 622|Homo sapiens protein ( Homo sapiens ... 38 0.27
AK001255-1|BAA91585.1| 622|Homo sapiens protein ( Homo sapiens ... 38 0.27
AF195417-1|AAF04150.1| 621|Homo sapiens DEAD-box protein abstra... 38 0.27
BC093081-1|AAH93081.1| 938|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 37 0.63
BC078667-1|AAH78667.1| 919|Homo sapiens DDX42 protein protein. 37 0.63
BC015505-1|AAH15505.1| 819|Homo sapiens DDX42 protein protein. 37 0.63
BC012304-1|AAH12304.1| 1031|Homo sapiens DEAD (Asp-Glu-Ala-Asp) ... 37 0.63
AF106680-1|AAD43033.1| 1031|Homo sapiens RNA helicase protein. 37 0.63
AF083255-1|AAC32396.1| 709|Homo sapiens RNA helicase-related pr... 37 0.63
AB036090-1|BAC66466.1| 938|Homo sapiens RNA helicase-related pr... 37 0.63
AB018344-1|BAA34521.2| 1058|Homo sapiens KIAA0801 protein protein. 37 0.63
BC014949-1|AAH14949.1| 678|Homo sapiens likely ortholog of mous... 36 0.83
AK021416-1|BAB13818.1| 678|Homo sapiens protein ( Homo sapiens ... 36 0.83
BC001417-1|AAH01417.4| 494|Homo sapiens ASCC3L1 protein protein. 36 1.1
U39817-1|AAA87850.1| 1417|Homo sapiens Bloom's syndrome protein ... 36 1.5
BC115032-1|AAI15033.1| 1417|Homo sapiens Bloom syndrome protein. 36 1.5
BC115030-1|AAI15031.1| 1417|Homo sapiens Bloom syndrome protein. 36 1.5
BC101567-1|AAI01568.1| 1417|Homo sapiens Bloom syndrome protein. 36 1.5
BC093622-1|AAH93622.1| 1417|Homo sapiens Bloom syndrome protein. 36 1.5
AY886902-1|AAW62255.1| 1417|Homo sapiens Bloom syndrome protein. 36 1.5
BC036112-1|AAH36112.1| 786|Homo sapiens suppressor of var1, 3-l... 35 1.9
BC007820-1|AAH07820.1| 299|Homo sapiens FLJ20035 protein protein. 35 1.9
AL596223-2|CAH71499.1| 786|Homo sapiens suppressor of var1, 3-l... 35 1.9
AK001649-1|BAA91809.1| 1174|Homo sapiens protein ( Homo sapiens ... 35 1.9
AF042169-1|AAB97370.1| 786|Homo sapiens putative ATP-dependent ... 35 1.9
BC074781-1|AAH74781.1| 402|Homo sapiens FLJ20035 protein protein. 34 4.4
AK223184-1|BAD96904.1| 409|Homo sapiens Hypothetical protein FL... 34 4.4
AK055595-1|BAB70966.1| 729|Homo sapiens protein ( Homo sapiens ... 34 4.4
AY684169-1|AAT74627.1| 3052|Homo sapiens REV3-like, catalytic su... 33 5.9
AL512325-2|CAI20998.1| 3130|Homo sapiens REV3-like, catalytic su... 33 5.9
AL512325-1|CAI20997.1| 3052|Homo sapiens REV3-like, catalytic su... 33 5.9
AL136310-1|CAI20509.1| 3130|Homo sapiens REV3-like, catalytic su... 33 5.9
AL080317-3|CAI19192.1| 3130|Homo sapiens REV3-like, catalytic su... 33 5.9
AL080317-2|CAI19191.1| 3052|Homo sapiens REV3-like, catalytic su... 33 5.9
AF179429-1|AAG09403.1| 3052|Homo sapiens DNA polymerase zeta cat... 33 5.9
AF179428-1|AAG09402.1| 3052|Homo sapiens DNA polymerase zeta cat... 33 5.9
AF157476-1|AAD40184.1| 3130|Homo sapiens DNA polymerase zeta cat... 33 5.9
AF155803-1|AAK56799.1| 824|Homo sapiens DEAD-box corepressor DP... 33 5.9
AF071798-1|AAC24009.1| 3130|Homo sapiens DNA polymerase zeta cat... 33 5.9
AF058701-1|AAC24357.1| 3130|Homo sapiens DNA polymerase zeta cat... 33 5.9
>AY338826-1|AAR08421.2| 2590|Homo sapiens DNA polymerase theta
protein.
Length = 2590
Score = 700 bits (1730), Expect = 0.0
Identities = 367/807 (45%), Positives = 516/807 (63%), Gaps = 42/807 (5%)
Query: 85 KIQSKKLKDWGLPIEISKKYEERGITEMFDWQLACLCNTKVLFDCANLVYSAPTSAGKTL 144
+I L +WGLP + +KY G+ +MF+WQ CL +VL + NLVYSAPTSAGKTL
Sbjct: 65 EIDKLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVL-EGKNLVYSAPTSAGKTL 123
Query: 145 VAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGSQSPAGGMQN 204
VAE+L +K VLE +KK + ILPFVS+ +EK +YLQ++ GI+V+G+MGS SP+ +
Sbjct: 124 VAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSS 183
Query: 205 VHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVTSK 264
+ +A+CTIE+AN +INRL++ ++ LG VVVDELH+LGD +RGY+LELLLTKI Y+T K
Sbjct: 184 LDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRK 243
Query: 265 S-----DLL------IQVIGMSATLPNLETLATWLNAELFITTFRPIPLEEYCLVENKYY 313
S DL +Q++GMSATLPNLE +A+WLNAEL+ T FRP+PL E V N Y
Sbjct: 244 SASCQADLASSLSNAVQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIY 303
Query: 314 DKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCK 373
D + K + E + D V+ +C ETI + SVL+FC +K CE LA +++ F
Sbjct: 304 DSSMKLVREFEPMLQVKGDEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYN 363
Query: 374 IGCEGSEFGMILRSQ-----LNSEHILEALEQLKNSPVGLDQILQKTISFGVGYHHAGLT 428
+ + G++ S+ L + +LE ++QL+ P GLD +LQKT+ +GV +HHAGLT
Sbjct: 364 LHHQAE--GLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLT 421
Query: 429 LDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQMSGRA 488
+ERDIIEGAF+ G IRVL ATSTLSSGVNLPAR+VIIR+P+F +P++IL+YKQM GRA
Sbjct: 422 FEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRA 481
Query: 489 GRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKE------KYMRAILEIIAS 542
GR G DT GESILIC +EK G L+ G L PV+SC++ +E +RAILEII
Sbjct: 482 GRKGVDTVGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVG 541
Query: 543 NISCSKQELLLYTDCTLLSAQ----KEILSQNL------ILEDTLKELENYELIR---IQ 589
++ + Q++ Y CT L+A K+ + +N +E + L E I+
Sbjct: 542 GVASTSQDMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEAS 601
Query: 590 NNHSENHYVATALGKACLSSSMAPNDGLTLFCELQKARQCLVLETDLHLIYLVTPYSVSS 649
+ Y T LG A LSSS++P D L +F +LQ+A + VLE DLH++YLVTP +
Sbjct: 602 DGTEGKVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTP--MFE 659
Query: 650 QWGNIDWLHLLNLWESLTKAMKKVGELVGVQESFIIKCLRGLNMKHLD--SNKLNIHKRF 707
W IDW LWE L +MK+V ELVGV+E F+ +C++G + + ++ IHKRF
Sbjct: 660 DWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRF 719
Query: 708 YTALALQDLVNEVHLSEVANKFQCARGFLQGLQQASGTFAGMVTAFCKQLGWKSMEILIS 767
+T+L L DL++EV L E+ K+ C RG +Q LQQ++ +AGM+T F +LGW +ME+L+S
Sbjct: 720 FTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLS 779
Query: 768 QFQDRLHFGIQXXXXXXXXXXXXNGMRARTLFDAGFEXXXXXXXXXXXXXENVLLKSVPF 827
QFQ RL FGIQ N RAR L+ +GF E +L +VPF
Sbjct: 780 QFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVEVEVILKNAVPF 839
Query: 828 ESAKERENDEKGDIKKRTKIKNIWISG 854
+SA++ ++E+ +++R ++ IW++G
Sbjct: 840 KSARKAVDEEEEAVEERRNMRTIWVTG 866
Score = 189 bits (461), Expect = 6e-47
Identities = 86/182 (47%), Positives = 123/182 (67%)
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDVDVFKSIAASWSDVPEGEV 1303
R+ F PG +++ADY QLE+R+L H S D L +++ + DVF+SIAA W + V
Sbjct: 2315 RHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTGADVFRSIAAEWKMIEPESV 2374
Query: 1304 DDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIEEC 1363
DDLRQ+AKQ+CYGIIYGMG K+L + + + E +A+ ++DSF+ Y I F ++ C
Sbjct: 2375 GDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNC 2434
Query: 1364 KRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGINS 1423
KR GFV+T+ GRRRYLP I + R+ AERQA+NT++QGSAADI K A +I+ + +
Sbjct: 2435 KRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLET 2494
Query: 1424 FN 1425
F+
Sbjct: 2495 FH 2496
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 39/218 (17%)
Query: 1060 SEKQQNALY--ESYQNAIN-VEIKVLKILSNCELHGIVVDKELVSRLLTDVRDSQDVLQK 1116
S Q N+L E+ Q+ VE+ L+ EL+GI ++ D ++
Sbjct: 2056 SMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIET 2115
Query: 1117 KAFKICGYHFNFNSSKDVAKVL--------------------------GIYNGRKT---- 1146
+A+++ G+ F+F SS D+A+VL GI NGRK
Sbjct: 2116 QAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGR 2175
Query: 1147 --STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKACI--YSEGDRIMSSYST 1200
ST K VL+ P+ +++ WR++ +TK+++PL + C+ + +RI +
Sbjct: 2176 QFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQS 2235
Query: 1201 FTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTSDEV 1238
T TGRIT EPN+QNVPR F I + L ++ S V
Sbjct: 2236 HTATGRITFTEPNIQNVPRDFEIKMPTLVGESPPSQAV 2273
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/53 (47%), Positives = 36/53 (67%)
Query: 1431 ILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWGALDE 1483
ILQ+HDEL+YEV E + + ++K+ ME V+L V L VK+K G +WG L +
Sbjct: 2535 ILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWGELKD 2587
>AY032677-1|AAK39635.1| 2724|Homo sapiens DNA polymerase theta
protein.
Length = 2724
Score = 697 bits (1722), Expect = 0.0
Identities = 366/807 (45%), Positives = 515/807 (63%), Gaps = 41/807 (5%)
Query: 85 KIQSKKLKDWGLPIEISKKYEERGITEMFDWQLACLCNTKVLFDCANLVYSAPTSAGKTL 144
+I L +WGLP + +KY G+ +MF+WQ CL +VL + NLVYSAPTSAGKTL
Sbjct: 198 EIDKLLLANWGLPKAVLEKYHSFGVKKMFEWQAECLLLGQVL-EGKNLVYSAPTSAGKTL 256
Query: 145 VAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGSQSPAGGMQN 204
VAE+L +K VLE +KK + ILPFVS+ +EK +YLQ++ GI+V+G+MGS SP+ +
Sbjct: 257 VAELLILKRVLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSS 316
Query: 205 VHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVTSK 264
+ +A+CTIE+AN +INRL++ ++ LG VVVDELH+LGD +RGY+LELLLTKI Y+T K
Sbjct: 317 LDIAVCTIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRK 376
Query: 265 S-----DL------LIQVIGMSATLPNLETLATWLNAELFITTFRPIPLEEYCLVENKYY 313
S DL +Q++GMSATLPNLE +A+WLNAEL+ T FRP+PL E V N Y
Sbjct: 377 SASCQADLASSLSNAVQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIY 436
Query: 314 DKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCK 373
D + K + E + D V+ +C ETI + SVL+FC +K CE LA +++ F
Sbjct: 437 DSSMKLVREFEPMLQVKGDEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIAREFYN 496
Query: 374 IGCEGSEFGMILRSQ-----LNSEHILEALEQLKNSPVGLDQILQKTISFGVGYHHAGLT 428
+ + G++ S+ L + +LE ++QL+ P GLD +LQKT+ +GV +HHAGLT
Sbjct: 497 LHHQAEGEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLT 556
Query: 429 LDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQMSGRA 488
+ERDIIEGAF+ G IRVL ATSTLSSGVNLPAR+VIIR+P+F +P++IL+YKQM GRA
Sbjct: 557 FEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRA 616
Query: 489 GRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKE------KYMRAILEIIAS 542
GR G DT G SILIC +EK G L+ G L PV+SC++ +E +RAILEII
Sbjct: 617 GRKGVDTVG-SILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVG 675
Query: 543 NISCSKQELLLYTDCTLLSAQ----KEILSQNL------ILEDTLKELENYELIR---IQ 589
++ + Q++ Y CT L+A K+ + +N +E + L E I+
Sbjct: 676 GVASTSQDMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEAS 735
Query: 590 NNHSENHYVATALGKACLSSSMAPNDGLTLFCELQKARQCLVLETDLHLIYLVTPYSVSS 649
+ Y T LG A LSSS++P D L +F +LQ+A + VLE DLH++YLVTP +
Sbjct: 736 DGTEGKVYHPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTP--MFE 793
Query: 650 QWGNIDWLHLLNLWESLTKAMKKVGELVGVQESFIIKCLRGLNMKHLD--SNKLNIHKRF 707
W IDW LWE L +MK+V ELVGV+E F+ +C++G + + ++ IHKRF
Sbjct: 794 DWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRF 853
Query: 708 YTALALQDLVNEVHLSEVANKFQCARGFLQGLQQASGTFAGMVTAFCKQLGWKSMEILIS 767
+T+L L DL++EV L E+ K+ C RG +Q LQQ++ +AGM+T F +LGW +ME+L+S
Sbjct: 854 FTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLS 913
Query: 768 QFQDRLHFGIQXXXXXXXXXXXXNGMRARTLFDAGFEXXXXXXXXXXXXXENVLLKSVPF 827
QFQ RL FGIQ N RAR L+ +GF E +L +VPF
Sbjct: 914 QFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVEVEVILKNAVPF 973
Query: 828 ESAKERENDEKGDIKKRTKIKNIWISG 854
+SA++ ++E+ +++R ++ IW++G
Sbjct: 974 KSARKAVDEEEEAVEERRNMRTIWVTG 1000
Score = 189 bits (461), Expect = 6e-47
Identities = 86/182 (47%), Positives = 123/182 (67%)
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDVDVFKSIAASWSDVPEGEV 1303
R+ F PG +++ADY QLE+R+L H S D L +++ + DVF+SIAA W + V
Sbjct: 2449 RHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTGADVFRSIAAEWKMIEPESV 2508
Query: 1304 DDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIEEC 1363
DDLRQ+AKQ+CYGIIYGMG K+L + + + E +A+ ++DSF+ Y I F ++ C
Sbjct: 2509 GDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNC 2568
Query: 1364 KRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGINS 1423
KR GFV+T+ GRRRYLP I + R+ AERQA+NT++QGSAADI K A +I+ + +
Sbjct: 2569 KRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLET 2628
Query: 1424 FN 1425
F+
Sbjct: 2629 FH 2630
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 39/218 (17%)
Query: 1060 SEKQQNALY--ESYQNAIN-VEIKVLKILSNCELHGIVVDKELVSRLLTDVRDSQDVLQK 1116
S Q N+L E+ Q+ VE+ L+ EL+GI ++ D ++
Sbjct: 2190 SMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIET 2249
Query: 1117 KAFKICGYHFNFNSSKDVAKVL--------------------------GIYNGRKT---- 1146
+A+++ G+ F+F SS D+A+VL GI NGRK
Sbjct: 2250 QAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGR 2309
Query: 1147 --STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKACI--YSEGDRIMSSYST 1200
ST K VL+ P+ +++ WR++ +TK+++PL + C+ + +RI +
Sbjct: 2310 QFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQS 2369
Query: 1201 FTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTSDEV 1238
T TGRIT EPN+QNVPR F I + L ++ S V
Sbjct: 2370 HTATGRITFTEPNIQNVPRDFEIKMPTLVGESPPSQAV 2407
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/53 (47%), Positives = 36/53 (67%)
Query: 1431 ILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWGALDE 1483
ILQ+HDEL+YEV E + + ++K+ ME V+L V L VK+K G +WG L +
Sbjct: 2669 ILQLHDELLYEVVEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWGELKD 2721
>AB209867-1|BAD93104.1| 2214|Homo sapiens DNA polymerase theta
variant protein.
Length = 2214
Score = 416 bits (1024), Expect = e-115
Identities = 216/489 (44%), Positives = 306/489 (62%), Gaps = 23/489 (4%)
Query: 387 SQLNSEHILEALEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRV 446
S + +LE ++QL+ P GLD +LQKT+ +GV +HHAGLT +ERDIIEGAF+ G IRV
Sbjct: 4 SNSGQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERDIIEGAFRQGLIRV 63
Query: 447 LVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEA 506
L ATSTLSSGVNLPAR+VIIR+P+F +P++IL+YKQM GRAGR G DT GESILIC +
Sbjct: 64 LAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGVDTVGESILICKNS 123
Query: 507 EKKIGFNLMMGDLDPVKSCIETKE------KYMRAILEIIASNISCSKQELLLYTDCTLL 560
EK G L+ G L PV+SC++ +E +RAILEII ++ + Q++ Y CT L
Sbjct: 124 EKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEIIVGGVASTSQDMHTYAACTFL 183
Query: 561 SAQKEILSQNLILEDTLKELENYE-----LIR---IQNNHSENH-----YVATALGKACL 607
+A + Q + +L E L+ IQ+ + + Y T LG A L
Sbjct: 184 AASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTEASDGTEGKVYHPTHLGSATL 243
Query: 608 SSSMAPNDGLTLFCELQKARQCLVLETDLHLIYLVTPYSVSSQWGNIDWLHLLNLWESLT 667
SSS++P D L +F +LQ+A + VLE DLH++YLVTP + W IDW LWE L
Sbjct: 244 SSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTP--MFEDWTTIDWYRFFCLWEKLP 301
Query: 668 KAMKKVGELVGVQESFIIKCLRGLNMKHLDSN--KLNIHKRFYTALALQDLVNEVHLSEV 725
+MK+V ELVGV+E F+ +C++G + + ++ IHKRF+T+L L DL++EV L E+
Sbjct: 302 TSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIHKRFFTSLVLLDLISEVPLREI 361
Query: 726 ANKFQCARGFLQGLQQASGTFAGMVTAFCKQLGWKSMEILISQFQDRLHFGIQXXXXXXX 785
K+ C RG +Q LQQ++ +AGM+T F +LGW +ME+L+SQFQ RL FGIQ
Sbjct: 362 NQKYGCNRGQIQSLQQSAAVYAGMITVFSNRLGWHNMELLLSQFQKRLTFGIQRELCDLV 421
Query: 786 XXXXXNGMRARTLFDAGFEXXXXXXXXXXXXXENVLLKSVPFESAKERENDEKGDIKKRT 845
N RAR L+ +GF E +L +VPF+SA++ ++E+ +++R
Sbjct: 422 RVSLLNAQRARVLYASGFHTVADLARANIVEVEVILKNAVPFKSARKAVDEEEEAVEERR 481
Query: 846 KIKNIWISG 854
++ IW++G
Sbjct: 482 NMRTIWVTG 490
Score = 189 bits (461), Expect = 6e-47
Identities = 86/182 (47%), Positives = 123/182 (67%)
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDVDVFKSIAASWSDVPEGEV 1303
R+ F PG +++ADY QLE+R+L H S D L +++ + DVF+SIAA W + V
Sbjct: 1939 RHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTGADVFRSIAAEWKMIEPESV 1998
Query: 1304 DDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIEEC 1363
DDLRQ+AKQ+CYGIIYGMG K+L + + + E +A+ ++DSF+ Y I F ++ C
Sbjct: 1999 GDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNC 2058
Query: 1364 KRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGINS 1423
KR GFV+T+ GRRRYLP I + R+ AERQA+NT++QGSAADI K A +I+ + +
Sbjct: 2059 KRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLET 2118
Query: 1424 FN 1425
F+
Sbjct: 2119 FH 2120
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 39/218 (17%)
Query: 1060 SEKQQNALY--ESYQNAIN-VEIKVLKILSNCELHGIVVDKELVSRLLTDVRDSQDVLQK 1116
S Q N+L E+ Q+ VE+ L+ EL+GI ++ D ++
Sbjct: 1680 SMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIET 1739
Query: 1117 KAFKICGYHFNFNSSKDVAKVL--------------------------GIYNGRKT---- 1146
+A+++ G+ F+F SS D+A+VL GI NGRK
Sbjct: 1740 QAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGR 1799
Query: 1147 --STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKACI--YSEGDRIMSSYST 1200
ST K VL+ P+ +++ WR++ +TK+++PL + C+ + +RI +
Sbjct: 1800 QFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQS 1859
Query: 1201 FTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTSDEV 1238
T TGRIT EPN+QNVPR F I + L ++ S V
Sbjct: 1860 HTATGRITFTEPNIQNVPRDFEIKMPTLVGESPPSQAV 1897
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/53 (47%), Positives = 36/53 (67%)
Query: 1431 ILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWGALDE 1483
ILQ+HDEL+YEV E + + ++K+ ME V+L V L VK+K G +WG L +
Sbjct: 2159 ILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWGELKD 2211
>AF436845-1|AAL85274.1| 1101|Homo sapiens DNA helicase HEL308 protein.
Length = 1101
Score = 376 bits (924), Expect = e-103
Identities = 267/806 (33%), Positives = 428/806 (53%), Gaps = 56/806 (6%)
Query: 33 SSLVVVKEYLEKSENKQKHVNRRFV-NTASNNSLLNKTAEGKLTA-SKEVRNTQKIQSKK 90
SS V + + ++ + H+ N + + +++ + K T S+E+ +K
Sbjct: 250 SSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTIESS 309
Query: 91 LKDWG----LPIEISKKYEE-RGITEMFDWQLACLCNTKVLFDCANLVYSAPTSAGKTLV 145
D G LP ++ Y + +GI ++++WQ CL V + NL+YS PTS GKTLV
Sbjct: 310 SNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQ-ERKNLIYSLPTSGGKTLV 368
Query: 146 AEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGSQS---PAGGM 202
AEIL ++ +L +K V++ILP+V+IV+EK+ L + G VE + GS+ P
Sbjct: 369 AEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRR 428
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ + I TIEK +S++N L++ G I+ LG VVVDELH++G+ +RG LE+ L KI Y T
Sbjct: 429 EKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILY-T 487
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAELFITTFRPIPLEEYCLVENKYYDKNGKY--- 319
SK+ Q+IGMSATL N+E L +L AE + + FRP+ L+EY + + Y+ + K
Sbjct: 488 SKTT---QIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENG 544
Query: 320 ILEAKSSNYGVSCN------DSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCK 373
+ ++ NY S D ++ + E I S L+FC +K CE++A+++ K
Sbjct: 545 MTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPN-YSCLVFCPSKKNCENVAEMICKFLSK 603
Query: 374 IGCEGSEFGMILRSQLNSEHILEALEQLKNSPVG-LDQILQKTISFGVGYHHAGLTLDER 432
+ E + E ++ LKN G L +L++TI FGV YHH+GLT DER
Sbjct: 604 EYLKHKE-----------KEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDER 652
Query: 433 DIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQMSGRAGRMG 492
++E A+ +G + + TSTL++GVNLPAR+VI+R+P K+ + YKQM GRAGR G
Sbjct: 653 KLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAG 712
Query: 493 RDTKGESILICSEAEKKIGFNLMMGDLDPVKSCI--ETKEKYMRAILEIIASNISCSKQE 550
DT GESILI E +K+ L+ L+ S + E + L +I I+ + +
Sbjct: 713 IDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDD 772
Query: 551 LLLYTDCTLLSAQKEILSQNL----ILEDTLKELENYELIR---IQNNHSENHY--VATA 601
+ + + T Q+++L + I ++L+ L L++ I + E Y T
Sbjct: 773 IYHFMNGTFFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITK 832
Query: 602 LGKACLSSSMAPNDGLTLFCELQKARQCLVLETDLHLIYLVTPYSVSSQWGNIDWLHLLN 661
LG+A ++ L+ +L+K + LVLE+ LHLIYL TPY + SQ N DW+
Sbjct: 833 LGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQC-NPDWMIYFR 891
Query: 662 LWESLTKAMKKVGELVGVQESFIIKCLRGLNM-KHLDSNKLNIHKRFYTALALQDLVNEV 720
+ L+ A + V ++GV ESFI K G + K +D N +N R Y + L L+ E
Sbjct: 892 QFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKNVVN---RLYLSFVLYTLLKET 948
Query: 721 HLSEVANKFQCARGFLQGLQQASGTFAGMVTAFCKQLG--WKSMEILISQFQDRLHFGIQ 778
++ V+ KF RG++Q L + +F+ V FC++L W +L+ + +L + ++
Sbjct: 949 NIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLV-ELTKKLTYCVK 1007
Query: 779 XXXXXXXXXXXXNGMRARTLFDAGFE 804
RA+ L+ AG++
Sbjct: 1008 AELIPLMEVTGVLEGRAKQLYSAGYK 1033
>DQ060036-1|AAY43130.1| 900|Homo sapiens polymerase (DNA directed) nu
protein.
Length = 900
Score = 195 bits (476), Expect = 9e-49
Identities = 139/488 (28%), Positives = 254/488 (52%), Gaps = 44/488 (9%)
Query: 1029 LTIKVN----NRQTKLKNLTLAQE-SCVKAWAIEMISEKQQNALYESYQNAINVEIKVLK 1083
+T+KVN N + N + + + +++ S+ + L++ ++ +E+ ++
Sbjct: 377 ITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGLWQLFRT---LELPLIP 433
Query: 1084 ILSNCELHGIVVDKELVSRLLTDVRDSQDVLQKKAFKICGYHFNFNSSKDVAKVL----- 1138
IL+ E H I V+KE + + + L+++A + G F S+ + ++L
Sbjct: 434 ILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLK 493
Query: 1139 -GIYNGRKT----------STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKA 1185
+ + R + ST ++VL++ P+ I++ +R+++ I + + L A
Sbjct: 494 LHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHKIKSTFVDGLL--A 551
Query: 1186 CIYSEGDRIMSSYSTFTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTS--DEVIEFNC 1243
C+ +G + T T TGR++ PN+Q + + P++ T N D+++ +
Sbjct: 552 CM-KKGSISSTWNQTGTVTGRLSAKHPNIQGISKH---PIQITTPKNFKGKEDKILTISP 607
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAASWSDVPEG 1301
R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ + W DVP
Sbjct: 608 RAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVE 667
Query: 1302 EVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIE 1361
+V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+ F ++ I
Sbjct: 668 QVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIA 727
Query: 1362 ECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGI 1421
+C + G V ++ GRRR LP I +H R AERQAVN ++QGSAAD+ K AM + +
Sbjct: 728 QCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAV 787
Query: 1422 -NSFNPKPRLILQMHDELIYEVHETNKSRFISLMKSVMED-------TVELKVPLPVKLK 1473
S RL+ Q+HDEL++EV + +L++ ME ++L+VPL V L
Sbjct: 788 AASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQVPLKVSLS 847
Query: 1474 CGYTWGAL 1481
G +WG L
Sbjct: 848 AGRSWGHL 855
>AY136549-1|AAN52116.1| 900|Homo sapiens DNA polymerase N protein.
Length = 900
Score = 195 bits (476), Expect = 9e-49
Identities = 139/488 (28%), Positives = 254/488 (52%), Gaps = 44/488 (9%)
Query: 1029 LTIKVN----NRQTKLKNLTLAQE-SCVKAWAIEMISEKQQNALYESYQNAINVEIKVLK 1083
+T+KVN N + N + + + +++ S+ + L++ ++ +E+ ++
Sbjct: 377 ITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGLWQLFRT---LELPLIP 433
Query: 1084 ILSNCELHGIVVDKELVSRLLTDVRDSQDVLQKKAFKICGYHFNFNSSKDVAKVL----- 1138
IL+ E H I V+KE + + + L+++A + G F S+ + ++L
Sbjct: 434 ILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLK 493
Query: 1139 -GIYNGRKT----------STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKA 1185
+ + R + ST ++VL++ P+ I++ +R+++ I + + L A
Sbjct: 494 LHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHKIKSTFVDGLL--A 551
Query: 1186 CIYSEGDRIMSSYSTFTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTS--DEVIEFNC 1243
C+ +G + T T TGR++ PN+Q + + P++ T N D+++ +
Sbjct: 552 CM-KKGSISSTWNQTGTVTGRLSAKHPNIQGISKH---PIQITTPKNFKGKEDKILTISP 607
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAASWSDVPEG 1301
R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ + W DVP
Sbjct: 608 RAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVE 667
Query: 1302 EVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIE 1361
+V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+ F ++ I
Sbjct: 668 QVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIA 727
Query: 1362 ECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGI 1421
+C + G V ++ GRRR LP I +H R AERQAVN ++QGSAAD+ K AM + +
Sbjct: 728 QCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAV 787
Query: 1422 -NSFNPKPRLILQMHDELIYEVHETNKSRFISLMKSVMED-------TVELKVPLPVKLK 1473
S RL+ Q+HDEL++EV + +L++ ME ++L+VPL V L
Sbjct: 788 AASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQVPLKVSLS 847
Query: 1474 CGYTWGAL 1481
G +WG L
Sbjct: 848 AGRSWGHL 855
>AL158068-2|CAM20461.1| 900|Homo sapiens polymerase (DNA directed) nu
protein.
Length = 900
Score = 195 bits (476), Expect = 9e-49
Identities = 139/488 (28%), Positives = 254/488 (52%), Gaps = 44/488 (9%)
Query: 1029 LTIKVN----NRQTKLKNLTLAQE-SCVKAWAIEMISEKQQNALYESYQNAINVEIKVLK 1083
+T+KVN N + N + + + +++ S+ + L++ ++ +E+ ++
Sbjct: 377 ITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGLWQLFRT---LELPLIP 433
Query: 1084 ILSNCELHGIVVDKELVSRLLTDVRDSQDVLQKKAFKICGYHFNFNSSKDVAKVL----- 1138
IL+ E H I V+KE + + + L+++A + G F S+ + ++L
Sbjct: 434 ILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLK 493
Query: 1139 -GIYNGRKT----------STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKA 1185
+ + R + ST ++VL++ P+ I++ +R+++ I + + L A
Sbjct: 494 LHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHKIKSTFVDGLL--A 551
Query: 1186 CIYSEGDRIMSSYSTFTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTS--DEVIEFNC 1243
C+ +G + T T TGR++ PN+Q + + P++ T N D+++ +
Sbjct: 552 CM-KKGSISSTWNQTGTVTGRLSAKHPNIQGISKH---PIQITTPKNFKGKEDKILTISP 607
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAASWSDVPEG 1301
R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ + W DVP
Sbjct: 608 RAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVE 667
Query: 1302 EVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIE 1361
+V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+ F ++ I
Sbjct: 668 QVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIA 727
Query: 1362 ECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGI 1421
+C + G V ++ GRRR LP I +H R AERQAVN ++QGSAAD+ K AM + +
Sbjct: 728 QCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAV 787
Query: 1422 -NSFNPKPRLILQMHDELIYEVHETNKSRFISLMKSVMED-------TVELKVPLPVKLK 1473
S RL+ Q+HDEL++EV + +L++ ME ++L+VPL V L
Sbjct: 788 AASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQVPLKVSLS 847
Query: 1474 CGYTWGAL 1481
G +WG L
Sbjct: 848 AGRSWGHL 855
>AL136360-1|CAM16854.1| 900|Homo sapiens polymerase (DNA directed) nu
protein.
Length = 900
Score = 195 bits (476), Expect = 9e-49
Identities = 139/488 (28%), Positives = 254/488 (52%), Gaps = 44/488 (9%)
Query: 1029 LTIKVN----NRQTKLKNLTLAQE-SCVKAWAIEMISEKQQNALYESYQNAINVEIKVLK 1083
+T+KVN N + N + + + +++ S+ + L++ ++ +E+ ++
Sbjct: 377 ITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGLWQLFRT---LELPLIP 433
Query: 1084 ILSNCELHGIVVDKELVSRLLTDVRDSQDVLQKKAFKICGYHFNFNSSKDVAKVL----- 1138
IL+ E H I V+KE + + + L+++A + G F S+ + ++L
Sbjct: 434 ILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLK 493
Query: 1139 -GIYNGRKT----------STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKA 1185
+ + R + ST ++VL++ P+ I++ +R+++ I + + L A
Sbjct: 494 LHLLSQRNSLPRTGLQKYPSTSEAVLNALRDLHPLPKIILEYRQVHKIKSTFVDGLL--A 551
Query: 1186 CIYSEGDRIMSSYSTFTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTS--DEVIEFNC 1243
C+ +G + T T TGR++ PN+Q + + P++ T N D+++ +
Sbjct: 552 CM-KKGSISSTWNQTGTVTGRLSAKHPNIQGISKH---PIQITTPKNFKGKEDKILTISP 607
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAASWSDVPEG 1301
R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ + W DVP
Sbjct: 608 RAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVE 667
Query: 1302 EVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIE 1361
+V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+ F ++ I
Sbjct: 668 QVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIA 727
Query: 1362 ECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGI 1421
+C + G V ++ GRRR LP I +H R AERQAVN ++QGSAAD+ K AM + +
Sbjct: 728 QCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAV 787
Query: 1422 -NSFNPKPRLILQMHDELIYEVHETNKSRFISLMKSVMED-------TVELKVPLPVKLK 1473
S RL+ Q+HDEL++EV + +L++ ME ++L+VPL V L
Sbjct: 788 AASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTMESLEQVQALELQLQVPLKVSLS 847
Query: 1474 CGYTWGAL 1481
G +WG L
Sbjct: 848 AGRSWGHL 855
>AF044578-1|AAD02338.1| 579|Homo sapiens putative DNA polymerase
protein.
Length = 579
Score = 194 bits (473), Expect = 2e-48
Identities = 137/481 (28%), Positives = 250/481 (51%), Gaps = 39/481 (8%)
Query: 1029 LTIKVN----NRQTKLKNLTLAQE-SCVKAWAIEMISEKQQNALYESYQNAINVEIKVLK 1083
+T+KVN N + N + + + +++ S+ + L++ ++ +E+ ++
Sbjct: 10 ITVKVNSTYGNSSRNIVNQNVRENLKTLYRLTMDLCSKLKDYGLWQLFRT---LELPLIP 66
Query: 1084 ILSNCELHGIVVDKELVSRLLTDVRDSQDVLQKKAFKICGYHFNFNSSKDVAKVL----- 1138
IL+ E H I V+KE + + + L+++A + G F S+ + ++L
Sbjct: 67 ILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLK 126
Query: 1139 -GIYNGRKTSTRKSVLSSHNT------------PISSIVMYWRKLNAILTKILYPLTEKA 1185
+ + R + R + +T P+ I++ +R+++ I + + L A
Sbjct: 127 LHLLSQRNSLPRTGLQKYPSTVSEALNALRDLHPLPKIILEYRQVHKIKSTFVDGLL--A 184
Query: 1186 CIYSEGDRIMSSYSTFTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTS--DEVIEFNC 1243
C+ +G + T T TGR++ PN+Q + + P++ T N D+++ +
Sbjct: 185 CM-KKGSISSTWNQTGTVTGRLSAKHPNIQGISKH---PIQITTPKNFKGKEDKILTISP 240
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAASWSDVPEG 1301
R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ + W DVP
Sbjct: 241 RAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTSQWKDVPVE 300
Query: 1302 EVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIE 1361
+V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+ F ++ I
Sbjct: 301 QVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIKDFARAAIA 360
Query: 1362 ECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGI 1421
+C + G V ++ GRRR LP I +H R AERQAVN ++QGSAAD+ K AM + +
Sbjct: 361 QCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQGSAADLCKLAMIHVFTAV 420
Query: 1422 -NSFNPKPRLILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWGA 1480
S RL+ Q+HDEL++EV + +L++ ME ++E +VPL V L G +WG
Sbjct: 421 AASHTLTARLVAQIHDELLFEVEDPQIPECAALVRRTME-SLE-QVPLKVSLSAGRSWGH 478
Query: 1481 L 1481
L
Sbjct: 479 L 479
>AF052573-1|AAC33565.1| 1762|Homo sapiens DNA polymerase theta
protein.
Length = 1762
Score = 189 bits (461), Expect = 6e-47
Identities = 86/182 (47%), Positives = 123/182 (67%)
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDVDVFKSIAASWSDVPEGEV 1303
R+ F PG +++ADY QLE+R+L H S D L +++ + DVF+SIAA W + V
Sbjct: 1487 RHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTGADVFRSIAAEWKMIEPESV 1546
Query: 1304 DDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIEEC 1363
DDLRQ+AKQ+CYGIIYGMG K+L + + + E +A+ ++DSF+ Y I F ++ C
Sbjct: 1547 GDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNC 1606
Query: 1364 KRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGINS 1423
KR GFV+T+ GRRRYLP I + R+ AERQA+NT++QGSAADI K A +I+ + +
Sbjct: 1607 KRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLET 1666
Query: 1424 FN 1425
F+
Sbjct: 1667 FH 1668
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 39/218 (17%)
Query: 1060 SEKQQNALY--ESYQNAIN-VEIKVLKILSNCELHGIVVDKELVSRLLTDVRDSQDVLQK 1116
S Q N+L E+ Q+ VE+ L+ EL+GI ++ D ++
Sbjct: 1228 SMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIET 1287
Query: 1117 KAFKICGYHFNFNSSKDVAKVL--------------------------GIYNGRKT---- 1146
+A+++ G+ F+F SS D+A+VL GI NGRK
Sbjct: 1288 QAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGR 1347
Query: 1147 --STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKACI--YSEGDRIMSSYST 1200
ST K VL+ P+ +++ WR++ +TK+++PL + C+ + +RI +
Sbjct: 1348 QFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQS 1407
Query: 1201 FTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTSDEV 1238
T TGRIT EPN+QNVPR F I + L ++ S V
Sbjct: 1408 HTATGRITFTEPNIQNVPRDFEIKMPTLVGESPPSQAV 1445
Score = 54.4 bits (125), Expect = 3e-06
Identities = 25/53 (47%), Positives = 36/53 (67%)
Query: 1431 ILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWGALDE 1483
ILQ+HDEL+YEV E + + ++K+ ME V+L V L VK+K G +WG L +
Sbjct: 1707 ILQLHDELLYEVVEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWGELKD 1759
>AF043628-1|AAD05272.1| 1154|Homo sapiens DNA polymerase eta protein.
Length = 1154
Score = 189 bits (461), Expect = 6e-47
Identities = 86/182 (47%), Positives = 123/182 (67%)
Query: 1244 RNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDVDVFKSIAASWSDVPEGEV 1303
R+ F PG +++ADY QLE+R+L H S D L +++ + DVF+SIAA W + V
Sbjct: 881 RHAFVPFPGGSILAADYSQLELRILAHLSHDRRLIQVLNTGADVFRSIAAEWKMIEPESV 940
Query: 1304 DDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIRVFTKSVIEEC 1363
DDLRQ+AKQ+CYGIIYGMG K+L + + + E +A+ ++DSF+ Y I F ++ C
Sbjct: 941 GDDLRQQAKQICYGIIYGMGAKSLGEQMGIKENDAACYIDSFKSRYTGINQFMTETVKNC 1000
Query: 1364 KRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSAADIAKSAMCSIEDGINS 1423
KR GFV+T+ GRRRYLP I + R+ AERQA+NT++QGSAADI K A +I+ + +
Sbjct: 1001 KRDGFVQTILGRRRYLPGIKDNNPYRKAHAERQAINTIVQGSAADIVKIATVNIQKQLET 1060
Query: 1424 FN 1425
F+
Sbjct: 1061 FH 1062
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 39/218 (17%)
Query: 1060 SEKQQNALY--ESYQNAIN-VEIKVLKILSNCELHGIVVDKELVSRLLTDVRDSQDVLQK 1116
S Q N+L E+ Q+ VE+ L+ EL+GI ++ D ++
Sbjct: 622 SMNQLNSLLQKENLQDVFRKVEMPSQYCLALLELNGIGFSTAECESQKHIMQAKLDAIET 681
Query: 1117 KAFKICGYHFNFNSSKDVAKVL--------------------------GIYNGRKT---- 1146
+A+++ G+ F+F SS D+A+VL GI NGRK
Sbjct: 682 QAYQLAGHSFSFTSSDDIAEVLFLELKLPPNREMKNQGSKKTLGSTRRGIDNGRKLRLGR 741
Query: 1147 --STRKSVLSSHNT--PISSIVMYWRKLNAILTKILYPLTEKACI--YSEGDRIMSSYST 1200
ST K VL+ P+ +++ WR++ +TK+++PL + C+ + +RI +
Sbjct: 742 QFSTSKDVLNKLKALHPLPGLILEWRRITNAITKVVFPLQREKCLNPFLGMERIYPVSQS 801
Query: 1201 FTCTGRITMHEPNLQNVPRTFSIPLRYLTFDNTTSDEV 1238
T TGRIT EPN+QNVPR F I + L ++ S V
Sbjct: 802 HTATGRITFTEPNIQNVPRDFEIKMPTLVGESPPSQAV 839
Score = 53.2 bits (122), Expect = 7e-06
Identities = 24/49 (48%), Positives = 34/49 (69%)
Query: 1431 ILQMHDELIYEVHETNKSRFISLMKSVMEDTVELKVPLPVKLKCGYTWG 1479
ILQ+HDEL+YEV E + + ++K+ ME V+L V L VK+K G +WG
Sbjct: 1101 ILQLHDELLYEVAEEDVVQVAQIVKNEMESAVKLSVKLKVKVKIGASWG 1149
>AK023840-1|BAB14698.1| 774|Homo sapiens protein ( Homo sapiens
cDNA FLJ13778 fis, clone PLACE4000431, highly similar to
H.sapiens gene for U5 snRNP-specific 200kD protein. ).
Length = 774
Score = 145 bits (351), Expect = 1e-33
Identities = 145/479 (30%), Positives = 225/479 (46%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 137 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETAENLLLCAPTGAGKTNVALMCMLRE 195
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 196 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLSKEEI 255
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 256 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 314
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE Y
Sbjct: 315 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLER------TYVG-- 366
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 367 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 418
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 419 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLLYGFAIHHAGMTRVDRTLV 472
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 473 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 532
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 533 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 589
>Z70200-1|CAA94089.1| 1701|Homo sapiens U5 snRNP-specific 200kD
protein protein.
Length = 1701
Score = 144 bits (349), Expect = 2e-33
Identities = 146/479 (30%), Positives = 226/479 (47%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 27 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 85
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 86 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 145
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +V+DE+HLL D +RG +LE L+ +
Sbjct: 146 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIVLDEIHLLHD-DRGPVLEALVARAIRNI 204
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 205 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 256
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 257 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 308
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 309 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 362
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 363 EDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 422
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 423 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 479
Score = 122 bits (295), Expect = 7e-27
Identities = 115/447 (25%), Positives = 216/447 (48%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFY-----LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + + + +E+++ Q+ L+
Sbjct: 910 NVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMRLWQEQVYMDWYEKFQDRLNKK 969
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 970 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1027
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1028 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1086
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + N + + + + AK + ++ S K V++F ++ +
Sbjct: 1087 PLELHIQGFNISHTQT-RLLSMAKPVFHAIT-KHSPKK----------PVIVFVPSRKQT 1134
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1135 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1182
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII ++ I+
Sbjct: 1183 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTLYYNGKIHAYV 1242
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1243 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1301
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1302 NA--EIVTKTIE-NKQDAVDYLTWTFL 1325
>BC112891-1|AAI12892.1| 1887|Homo sapiens Unknown (protein for
IMAGE:6042731) protein.
Length = 1887
Score = 144 bits (349), Expect = 2e-33
Identities = 145/479 (30%), Positives = 226/479 (47%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 213 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 271
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 272 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 331
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 332 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 390
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 391 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 442
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 443 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 494
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 495 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 548
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 549 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 608
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 609 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 665
Score = 122 bits (294), Expect = 1e-26
Identities = 116/447 (25%), Positives = 210/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 1096 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1155
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 1156 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1213
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1214 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1272
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 1273 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 1320
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1321 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1368
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 1369 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 1428
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1429 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1487
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1488 NA--EIVTKTIE-NKQDAVDYLTWTFL 1511
>AY572488-1|AAS78571.1| 2136|Homo sapiens 200 kDa U5 snRNP-specific
spliceosomal protein protein.
Length = 2136
Score = 144 bits (349), Expect = 2e-33
Identities = 145/479 (30%), Positives = 226/479 (47%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 462 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 520
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 521 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 580
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 581 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 639
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 640 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 691
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 692 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 743
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 744 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 797
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 798 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 857
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 858 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 914
Score = 122 bits (294), Expect = 1e-26
Identities = 116/447 (25%), Positives = 210/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 1345 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1404
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 1405 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1462
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1463 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1521
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 1522 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 1569
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1570 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1617
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 1618 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 1677
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1678 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1736
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1737 NA--EIVTKTIE-NKQDAVDYLTWTFL 1760
>AK024391-1|BAB14906.1| 1811|Homo sapiens protein ( Homo sapiens
cDNA FLJ14329 fis, clone PLACE4000259, highly similar to
H.sapiens gene for U5 snRNP-specific 200kD protein. ).
Length = 1811
Score = 144 bits (349), Expect = 2e-33
Identities = 145/479 (30%), Positives = 226/479 (47%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 137 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 195
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 196 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 255
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 256 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 314
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 315 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 366
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 367 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 418
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 419 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 472
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 473 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGHWTELGALDILQMLGRAG 532
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 533 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 589
Score = 118 bits (285), Expect = 1e-25
Identities = 115/447 (25%), Positives = 209/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 1020 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1079
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 1080 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1137
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++ ++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1138 N-GPVLEVICSRMRNISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1196
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 1197 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 1244
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1245 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1292
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 1293 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 1352
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1353 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1411
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1412 NA--EIVTKTIE-NKQDAVDYLTWTFL 1435
>AB018331-1|BAA34508.2| 2026|Homo sapiens KIAA0788 protein protein.
Length = 2026
Score = 144 bits (349), Expect = 2e-33
Identities = 145/479 (30%), Positives = 226/479 (47%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 352 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 410
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 411 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 470
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ +CT EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 471 SATQIIVCTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 529
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 530 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 581
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 582 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 633
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 634 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 687
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 688 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 747
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 748 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 804
Score = 122 bits (294), Expect = 1e-26
Identities = 116/447 (25%), Positives = 210/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 1235 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1294
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 1295 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1352
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1353 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1411
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 1412 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 1459
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1460 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1507
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 1508 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 1567
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1568 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1626
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1627 NA--EIVTKTIE-NKQDAVDYLTWTFL 1650
>BC065924-1|AAH65924.1| 1821|Homo sapiens ASCC3L1 protein protein.
Length = 1821
Score = 140 bits (338), Expect = 5e-32
Identities = 144/479 (30%), Positives = 225/479 (46%), Gaps = 52/479 (10%)
Query: 96 LPIEISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIK- 152
LP+E KY + G E F ++ L NL+ APT AGKT VA + ++
Sbjct: 147 LPVEKLPKYAQAGF-EGFKTLNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLRE 205
Query: 153 ---------TVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS-QSPAGGM 202
T+ K+I I P S+V+E + L++ GI V G Q +
Sbjct: 206 IGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEI 265
Query: 203 QNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVT 262
+ + T EK + + + + + + +++DE+HLL D +RG +LE L+ +
Sbjct: 266 SATQIIVFTPEKWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNI 324
Query: 263 SKSDLLIQVIGMSATLPNLETLATWLNAE------LFITTFRPIPLEEYCLVENKYYDKN 316
+ +++IG+SATLPN E +AT+L + F +FRP+PLE+ Y
Sbjct: 325 EMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQ------TYVG-- 376
Query: 317 GKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
I E K+ N+ V + +E + VL+F ++ A+ + C
Sbjct: 377 ---ITEKKAIKRFQIMNEIVYEKIMEHAGKN-QVLVFVHSRKETGKTARAIRD-MC---L 428
Query: 377 EGSEFGMILRSQLNSEHILEA-LEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDII 435
E G+ LR S +L EQ KN L+ + +G HHAG+T +R ++
Sbjct: 429 EKDTLGLFLREGSASTEVLRTEAEQCKNLE------LKDLLPYGFAIHHAGMTRVDRTLV 482
Query: 436 EGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQKQ-----PINILSYKQMSGRAG 489
E F I+VLV+T+TL+ GVNLPA VII+ + V+ + + L QM GRAG
Sbjct: 483 EDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAG 542
Query: 490 RMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRAILEIIASNISCSK 548
R DTKGE ILI S E + +L+ L P++S + +K M EI+ N+ +K
Sbjct: 543 RPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-LNAEIVLGNVQNAK 599
Score = 122 bits (294), Expect = 1e-26
Identities = 116/447 (25%), Positives = 210/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 1030 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1089
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 1090 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 1147
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 1148 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 1206
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 1207 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 1254
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 1255 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 1302
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 1303 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 1362
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 1363 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 1421
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 1422 NA--EIVTKTIE-NKQDAVDYLTWTFL 1445
>AB204867-1|BAF45466.1| 1435|Homo sapiens helicase-like protein HFM1
protein.
Length = 1435
Score = 126 bits (303), Expect = 8e-28
Identities = 126/490 (25%), Positives = 226/490 (46%), Gaps = 59/490 (12%)
Query: 45 SENKQKHVNRRFVNTASNNSLLNKTAEGKLTASK-----EVRNTQKIQSKKLKDWGLPIE 99
S +KQK V TA+N ++ EG A + + Q++ L E
Sbjct: 207 SNSKQKFQYSANVFTANNAFSASEIGEGMFKAPSFSVAFQPHDIQEVTENGLGSLKAVTE 266
Query: 100 ISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIKTVLE- 156
I K+ R I + F + + +L+ N V APT +GKT+V E+ + ++E
Sbjct: 267 IPAKF--RSIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEV 324
Query: 157 ----RQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS--QSPAGGMQNVHVAIC 210
K++ + P ++ ++ + G+ + G +Q+ H+ +
Sbjct: 325 PLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMT 384
Query: 211 TIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVTSKSDLL-- 268
T EK +SM + DN ++ + +++DE+H++ D+NRG LE++++++K V S S L
Sbjct: 385 TPEKWDSMTRKWRDNSLVQLVRLLLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKN 444
Query: 269 ------IQVIGMSATLPNLETLATWLNAELFITTFRPIPLEEYCLVENKYYDKNGKYILE 322
++ + +SAT+PN E +A WL+ RP + + E+ K K +L
Sbjct: 445 TSTAIPMRFVAVSATIPNAEDIAEWLS-----DGERPAVCLK--MDESHRPVKLQKVVLG 497
Query: 323 AK-SSN-----YGVSCNDSVLKICLETIKEGCSVLIFCMTKNRCESLAQLLSSTFCKIGC 376
SSN + ++ N + + ++ + L+FC T+ + A +L
Sbjct: 498 FPCSSNQTEFKFDLTLNYKIASV-IQMYSDQKPTLVFCATRKGVQQAASVL--------V 548
Query: 377 EGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGVGYHHAGLTLDERDIIE 436
+ ++F M + + + L++ S D L+ + G YHHAG+ L +R ++E
Sbjct: 549 KDAKFIMTVEQK-------QRLQKYAYSV--RDSKLRDILKDGAAYHHAGMELSDRKVVE 599
Query: 437 GAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK----QPINILSYKQMSGRAGRMG 492
GAF G + VL TSTL+ GVNLPA V+I+S + + + QM GRAGR
Sbjct: 600 GAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGLFEEYSETDILQMIGRAGRPQ 659
Query: 493 RDTKGESILI 502
DT ++++
Sbjct: 660 FDTTATAVIM 669
>AK131239-1|BAD18421.1| 312|Homo sapiens protein ( Homo sapiens cDNA
FLJ16155 fis, clone BRAWH1000369, highly similar to Homo
sapiens putative DNA polymerase mRNA. ).
Length = 312
Score = 125 bits (302), Expect = 1e-27
Identities = 61/173 (35%), Positives = 104/173 (60%), Gaps = 2/173 (1%)
Query: 1236 DEVIEFNCRNVFRAAPGSVMVSADYCQLEMRLLTHFSEDSALTRIMKSDV--DVFKSIAA 1293
D+++ + R +F ++ G ++AD+ Q+E+R+LTH S D L ++ + DVF ++ +
Sbjct: 132 DKILTISPRAMFVSSKGHTFLAADFSQIELRILTHLSGDPELLKLFQESERDDVFSTLTS 191
Query: 1294 SWSDVPEGEVDDDLRQKAKQLCYGIIYGMGNKTLSQHLDVSEMEASLFMDSFERTYPAIR 1353
W DVP +V R++ K++ Y ++YG G + L+ L V EA+ F++SF + Y I+
Sbjct: 192 QWKDVPVEQVTHADREQTKKVVYAVVYGAGKERLAACLGVPIQEAAQFLESFLQKYKKIK 251
Query: 1354 VFTKSVIEECKRQGFVETLSGRRRYLPDITSHITSRRNTAERQAVNTMIQGSA 1406
F ++ I +C + G V ++ GRRR LP I +H R AERQAVN ++Q +
Sbjct: 252 DFARAAIAQCHQTGCVVSIMGRRRPLPRIHAHDQQLRAQAERQAVNFVVQAQS 304
>BC007577-1|AAH07577.1| 1308|Homo sapiens ASCC3L1 protein protein.
Length = 1308
Score = 122 bits (294), Expect = 1e-26
Identities = 116/447 (25%), Positives = 210/447 (46%), Gaps = 48/447 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQK-KVIIILPFVSIVREKM--FY--LQNILSSS 185
N+ APT +GKT+ AE ++ +L+ + + + I P ++ + +Y Q+ L+
Sbjct: 517 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 576
Query: 186 GIRVEGFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQ 245
+ + G + G N+ I T EK + + R N++++ VVDE+HL+G +
Sbjct: 577 VVLLTGETSTDLKLLGKGNI--IISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIGGE 634
Query: 246 NRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPI 300
N G +LE++ ++++Y++S+ + I+++ +S++L N + +A WL F RP+
Sbjct: 635 N-GPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTFNFHPNVRPV 693
Query: 301 PLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIFCMTKNRC 360
PLE + ++ +L Y S K V++F ++ +
Sbjct: 694 PLELH--IQGFNISHTQTRLLSMAKPVYHAITKHSPKK----------PVIVFVPSRKQT 741
Query: 361 ESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISFGV 420
L + T C + F + ++ LE+L D L++T+ GV
Sbjct: 742 R-LTAIDILTTCAADIQRQRF-----LHCTEKDLIPYLEKLS------DSTLKETLLNGV 789
Query: 421 GYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN--- 477
GY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII + I+
Sbjct: 790 GYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYV 849
Query: 478 ---ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYM 533
I QM G A R +D +G +++C + KK F + + PV+S ++ +
Sbjct: 850 DYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHF 908
Query: 534 RAILEIIASNISCSKQELLLYTDCTLL 560
A EI+ I +KQ+ + Y T L
Sbjct: 909 NA--EIVTKTIE-NKQDAVDYLTWTFL 932
Score = 40.3 bits (90), Expect = 0.051
Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 476 INILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYMRA 535
+ L QM GRAGR DTKGE ILI S E + +L+ L P++S + +K M
Sbjct: 16 LGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQL-PIESQMVSKLPDM-L 73
Query: 536 ILEIIASNISCSK 548
EI+ N+ +K
Sbjct: 74 NAEIVLGNVQNAK 86
>Z86062-1|CAI19454.1| 2193|Homo sapiens RP1-121G13.4 protein.
Length = 2193
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 485 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 544
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 545 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 604
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 605 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 663
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 664 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 712
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 713 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 763
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 764 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 823
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 824 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 879
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1333 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1391
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1392 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1451
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1452 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1510
Query: 300 IPLE 303
+PLE
Sbjct: 1511 VPLE 1514
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1596 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1655
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1656 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1715
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1716 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1748
>AY013288-1|AAG45474.1| 1917|Homo sapiens ASC-1 complex subunit P200
protein.
Length = 1917
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 218 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 277
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 278 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 337
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 338 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 396
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 397 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 445
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 446 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 496
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 497 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 556
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 557 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 612
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1066 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1124
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1125 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1184
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1185 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1243
Query: 300 IPLE 303
+PLE
Sbjct: 1244 VPLE 1247
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1329 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1388
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1389 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1448
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1449 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1481
>AL591585-1|CAH73862.1| 2193|Homo sapiens RP1-121G13.4 protein.
Length = 2193
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 485 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 544
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 545 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 604
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 605 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 663
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 664 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 712
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 713 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 763
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 764 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 823
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 824 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 879
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1333 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1391
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1392 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1451
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1452 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1510
Query: 300 IPLE 303
+PLE
Sbjct: 1511 VPLE 1514
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1596 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1655
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1656 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1715
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1716 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1748
>AL356122-1|CAI16190.1| 2193|Homo sapiens RP1-121G13.4 protein.
Length = 2193
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 485 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 544
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 545 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 604
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 605 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 663
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 664 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 712
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 713 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 763
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 764 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 823
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 824 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 879
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1333 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1391
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1392 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1451
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1452 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1510
Query: 300 IPLE 303
+PLE
Sbjct: 1511 VPLE 1514
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1596 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1655
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1656 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1715
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1716 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1748
>AL133338-2|CAI21439.1| 2193|Homo sapiens RP1-121G13.4 protein.
Length = 2193
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 485 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 544
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 545 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 604
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 605 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 663
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 664 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 712
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 713 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 763
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 764 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 823
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 824 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 879
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1333 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1391
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1392 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1451
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1452 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1510
Query: 300 IPLE 303
+PLE
Sbjct: 1511 VPLE 1514
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1596 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1655
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1656 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1715
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1716 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1748
>AL121965-1|CAI19627.1| 2193|Homo sapiens RP1-121G13.4 protein.
Length = 2193
Score = 118 bits (285), Expect = 1e-25
Identities = 110/417 (26%), Positives = 202/417 (48%), Gaps = 45/417 (10%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 485 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 544
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + + T EK + + + + + + + +++DE+
Sbjct: 545 LEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEV 604
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTF-- 297
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I F
Sbjct: 605 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 663
Query: 298 ----RPIPLEEYCLVENKYYDKNGKYILEAKSSNYGVSCNDSVLKICLETIKEGCSVLIF 353
RP+PL + L K +K + +N C ++VLK +K G V++F
Sbjct: 664 DGRFRPVPLGQTFL-GIKCANKMQQL------NNMDEVCYENVLK----QVKAGHQVMVF 712
Query: 354 CMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQ 413
+N A L G +Q +++L A +Q++ S ++ ++
Sbjct: 713 VHARNATVRTAMSLIERAKNCG----HIPFFFPTQ-GHDYVL-AEKQVQRSR---NKQVR 763
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR-SPVFQ 472
+ G HHAG+ +R+++E F +G I+VLV T+TL+ GVNLPA VII+ + ++
Sbjct: 764 ELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYA 823
Query: 473 KQ-----PINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+ + IL Q+ GRAGR D GE I+I + +K + ++ +P++S
Sbjct: 824 AKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTH-DKLSHYLTLLTQRNPIES 879
Score = 87.4 bits (207), Expect = 3e-16
Identities = 52/184 (28%), Positives = 100/184 (54%), Gaps = 10/184 (5%)
Query: 128 DCANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSS 185
DC N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I
Sbjct: 1333 DC-NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKL 1391
Query: 186 GIRVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGD 244
G +V G +P + + + T EK + + + ++ + +++DE+HLLG+
Sbjct: 1392 GKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGE 1451
Query: 245 QNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRP 299
+ RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP
Sbjct: 1452 E-RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRP 1510
Query: 300 IPLE 303
+PLE
Sbjct: 1511 VPLE 1514
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 1596 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 1655
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 1656 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 1715
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 1716 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 1748
>Z48796-1|CAA88733.1| 1246|Homo sapiens helicase protein.
Length = 1246
Score = 101 bits (241), Expect = 3e-20
Identities = 114/431 (26%), Positives = 186/431 (43%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQILQ--KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+LQ + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLQMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>D29641-1|BAA06124.2| 1046|Homo sapiens KIAA0052 protein protein.
Length = 1046
Score = 101 bits (241), Expect = 3e-20
Identities = 113/447 (25%), Positives = 188/447 (42%), Gaps = 64/447 (14%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVE 190
+++ SA TSAGKT+ AE I L +++VI P ++ +K + G+ +
Sbjct: 160 SVLVSAHTSAGKTVCAEY-AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL-MT 217
Query: 191 GFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYI 250
G + A + + T E SM+ R + + ++ V+ DE+H + D RG +
Sbjct: 218 GDVTINPTASCL------VMTTEILRSMLYR--GSEVMREVAWVIFDEIHYMRDSERGVV 269
Query: 251 LELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL------NAELFITTFRPIPLEE 304
E + + + + +SAT+PN A W+ + T +RP PL+
Sbjct: 270 WEETIILLPDN-------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQH 322
Query: 305 YCLVE-----NKYYDKNGKY----------IL---------EAKSSNYGVSCNDSVLKIC 340
Y + D+NG + +L + K G +V KI
Sbjct: 323 YIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV 382
Query: 341 LETIKEGCS-VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALE 399
++ V+IF +K CE+ A ++ +F ++ E A++
Sbjct: 383 KMIMERNFQPVIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAID 433
Query: 400 QLKNSPVGLDQI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGV 457
L + L Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+
Sbjct: 434 CLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGI 493
Query: 458 NLPARKVII-RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGF 512
N+PAR V+ + F + +S Y QMSGRAGR G D +G IL+ E IG
Sbjct: 494 NMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGK 553
Query: 513 NLMMGDLDPVKSCIETKEKYMRAILEI 539
L+ G DP+ S + +L +
Sbjct: 554 QLLKGSADPLNSAFHLTYNMVLNLLRV 580
>BC113509-1|AAI13510.1| 1042|Homo sapiens superkiller viralicidic
activity 2-like 2 (S. cerevisiae) protein.
Length = 1042
Score = 101 bits (241), Expect = 3e-20
Identities = 113/447 (25%), Positives = 188/447 (42%), Gaps = 64/447 (14%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVE 190
+++ SA TSAGKT+ AE I L +++VI P ++ +K + G+ +
Sbjct: 156 SVLVSAHTSAGKTVCAEY-AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL-MT 213
Query: 191 GFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYI 250
G + A + + T E SM+ R + + ++ V+ DE+H + D RG +
Sbjct: 214 GDVTINPTASCL------VMTTEILRSMLYR--GSEVMREVAWVIFDEIHYMRDSERGVV 265
Query: 251 LELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL------NAELFITTFRPIPLEE 304
E + + + + +SAT+PN A W+ + T +RP PL+
Sbjct: 266 WEETIILLPDN-------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQH 318
Query: 305 YCLVE-----NKYYDKNGKY----------IL---------EAKSSNYGVSCNDSVLKIC 340
Y + D+NG + +L + K G +V KI
Sbjct: 319 YIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV 378
Query: 341 LETIKEGCS-VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALE 399
++ V+IF +K CE+ A ++ +F ++ E A++
Sbjct: 379 KMIMERNFQPVIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAID 429
Query: 400 QLKNSPVGLDQI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGV 457
L + L Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+
Sbjct: 430 CLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGI 489
Query: 458 NLPARKVII-RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGF 512
N+PAR V+ + F + +S Y QMSGRAGR G D +G IL+ E IG
Sbjct: 490 NMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGK 549
Query: 513 NLMMGDLDPVKSCIETKEKYMRAILEI 539
L+ G DP+ S + +L +
Sbjct: 550 QLLKGSADPLNSAFHLTYNMVLNLLRV 576
>BC104996-1|AAI04997.1| 1042|Homo sapiens superkiller viralicidic
activity 2-like 2 (S. cerevisiae) protein.
Length = 1042
Score = 101 bits (241), Expect = 3e-20
Identities = 113/447 (25%), Positives = 188/447 (42%), Gaps = 64/447 (14%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVE 190
+++ SA TSAGKT+ AE I L +++VI P ++ +K + G+ +
Sbjct: 156 SVLVSAHTSAGKTVCAEY-AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL-MT 213
Query: 191 GFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYI 250
G + A + + T E SM+ R + + ++ V+ DE+H + D RG +
Sbjct: 214 GDVTINPTASCL------VMTTEILRSMLYR--GSEVMREVAWVIFDEIHYMRDSERGVV 265
Query: 251 LELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL------NAELFITTFRPIPLEE 304
E + + + + +SAT+PN A W+ + T +RP PL+
Sbjct: 266 WEETIILLPDN-------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQH 318
Query: 305 YCLVE-----NKYYDKNGKY----------IL---------EAKSSNYGVSCNDSVLKIC 340
Y + D+NG + +L + K G +V KI
Sbjct: 319 YIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV 378
Query: 341 LETIKEGCS-VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALE 399
++ V+IF +K CE+ A ++ +F ++ E A++
Sbjct: 379 KMIMERNFQPVIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAID 429
Query: 400 QLKNSPVGLDQI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGV 457
L + L Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+
Sbjct: 430 CLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGI 489
Query: 458 NLPARKVII-RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGF 512
N+PAR V+ + F + +S Y QMSGRAGR G D +G IL+ E IG
Sbjct: 490 NMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGK 549
Query: 513 NLMMGDLDPVKSCIETKEKYMRAILEI 539
L+ G DP+ S + +L +
Sbjct: 550 QLLKGSADPLNSAFHLTYNMVLNLLRV 576
>BC065258-1|AAH65258.1| 1043|Homo sapiens SKIV2L2 protein protein.
Length = 1043
Score = 101 bits (241), Expect = 3e-20
Identities = 113/447 (25%), Positives = 188/447 (42%), Gaps = 64/447 (14%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVE 190
+++ SA TSAGKT+ AE I L +++VI P ++ +K + G+ +
Sbjct: 157 SVLVSAHTSAGKTVCAEY-AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL-MT 214
Query: 191 GFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYI 250
G + A + + T E SM+ R + + ++ V+ DE+H + D RG +
Sbjct: 215 GDVTINPTASCL------VMTTEILRSMLYR--GSEVMREVAWVIFDEIHYMRDSERGVV 266
Query: 251 LELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL------NAELFITTFRPIPLEE 304
E + + + + +SAT+PN A W+ + T +RP PL+
Sbjct: 267 WEETIILLPDN-------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQH 319
Query: 305 YCLVE-----NKYYDKNGKY----------IL---------EAKSSNYGVSCNDSVLKIC 340
Y + D+NG + +L + K G +V KI
Sbjct: 320 YIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV 379
Query: 341 LETIKEGCS-VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALE 399
++ V+IF +K CE+ A ++ +F ++ E A++
Sbjct: 380 KMIMERNFQPVIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAID 430
Query: 400 QLKNSPVGLDQI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGV 457
L + L Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+
Sbjct: 431 CLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGI 490
Query: 458 NLPARKVII-RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGF 512
N+PAR V+ + F + +S Y QMSGRAGR G D +G IL+ E IG
Sbjct: 491 NMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGK 550
Query: 513 NLMMGDLDPVKSCIETKEKYMRAILEI 539
L+ G DP+ S + +L +
Sbjct: 551 QLLKGSADPLNSAFHLTYNMVLNLLRV 577
>BC028604-1|AAH28604.3| 1042|Homo sapiens superkiller viralicidic
activity 2-like 2 (S. cerevisiae) protein.
Length = 1042
Score = 101 bits (241), Expect = 3e-20
Identities = 113/447 (25%), Positives = 188/447 (42%), Gaps = 64/447 (14%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVE 190
+++ SA TSAGKT+ AE I L +++VI P ++ +K + G+ +
Sbjct: 156 SVLVSAHTSAGKTVCAEY-AIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGL-MT 213
Query: 191 GFMGSQSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYI 250
G + A + + T E SM+ R + + ++ V+ DE+H + D RG +
Sbjct: 214 GDVTINPTASCL------VMTTEILRSMLYR--GSEVMREVAWVIFDEIHYMRDSERGVV 265
Query: 251 LELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL------NAELFITTFRPIPLEE 304
E + + + + +SAT+PN A W+ + T +RP PL+
Sbjct: 266 WEETIILLPDN-------VHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQH 318
Query: 305 YCLVE-----NKYYDKNGKY----------IL---------EAKSSNYGVSCNDSVLKIC 340
Y + D+NG + +L + K G +V KI
Sbjct: 319 YIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIV 378
Query: 341 LETIKEGCS-VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALE 399
++ V+IF +K CE+ A ++ +F ++ E A++
Sbjct: 379 KMIMERNFQPVIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAID 429
Query: 400 QLKNSPVGLDQI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGV 457
L + L Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+
Sbjct: 430 CLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGI 489
Query: 458 NLPARKVII-RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGF 512
N+PAR V+ + F + +S Y QMSGRAGR G D +G IL+ E IG
Sbjct: 490 NMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGK 549
Query: 513 NLMMGDLDPVKSCIETKEKYMRAILEI 539
L+ G DP+ S + +L +
Sbjct: 550 QLLKGSADPLNSAFHLTYNMVLNLLRV 576
>U09877-1|AAB52523.1| 1245|Homo sapiens helicase-like protein
protein.
Length = 1245
Score = 99 bits (238), Expect = 6e-20
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 330 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALTNQKFRDFRNTFGDVGLLT----- 383
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 384 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 437
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 438 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 490
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 491 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 550
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 551 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 610
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 611 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 670
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 671 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 730
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 731 MMMGKPSQLQS 741
>X98378-1|CAA67024.1| 1246|Homo sapiens SKI2W protein protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>CR753822-4|CAM26058.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>BX005143-14|CAM25870.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>BC015758-1|AAH15758.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AL844853-15|CAI41863.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AL662849-12|CAI17460.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AL645922-13|CAI41730.1| 1246|Homo sapiens superkiller viralicidic
activity 2-like (S. cerevisiae) protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AL049547-13|CAB89307.1| 1245|Homo sapiens dJ34F7.7 (superkiller
viralicidic activity 2 (S. cerevisiae homolog)-like
(SKI2 protein.
Length = 1245
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 330 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 383
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 384 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 437
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 438 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 490
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 491 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 550
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 551 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 610
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 611 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 670
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 671 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 730
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 731 MMMGKPSQLQS 741
>AF059675-1|AAC78607.1| 1246|Homo sapiens putative RNA helicase
Ski2w protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AF019413-6|AAB67978.1| 1246|Homo sapiens helicase protein.
Length = 1246
Score = 99.1 bits (236), Expect = 1e-19
Identities = 113/431 (26%), Positives = 185/431 (42%), Gaps = 60/431 (13%)
Query: 135 SAPTSAGKTLVAEILTIKTVLERQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMG 194
+A TSAGKT+VAE I + + I P ++ +K +N G+
Sbjct: 331 AAHTSAGKTVVAEY-AIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLT----- 384
Query: 195 SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN--IEDLGAVVVDELHLLGDQNRGYILE 252
G +Q A C I ++ +L +G+ I DL V+ DE+H + D RG + E
Sbjct: 385 -----GDVQLHPEASCLI-MTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWE 438
Query: 253 LLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWL----NAELFI--TTFRPIPLEEYC 306
+L + S +I +SAT+PN A W+ ++++ T RP+PLE Y
Sbjct: 439 EVLIMLPDHVS-------IILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYL 491
Query: 307 LVENKYYDKNGKYIL-------EAKSSNYGVSCNDSVLKICLETI-----------KEGC 348
N + ++L K V + +T +
Sbjct: 492 FTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDR 551
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGM----ILRSQLNSE-HIL--EALEQL 401
V + + R + ++ TF + C+ G+ + S SE H+ L +L
Sbjct: 552 GVYLSLLASLRTRAQLPVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARL 611
Query: 402 KNSPVGLDQIL--QKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNL 459
+ S L Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+
Sbjct: 612 RGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNM 671
Query: 460 PARKVIIRSPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FN 513
PAR V+ S ++L Y QM+GRAGR G D G IL+C ++
Sbjct: 672 PARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHR 731
Query: 514 LMMGDLDPVKS 524
+MMG ++S
Sbjct: 732 MMMGKPSQLQS 742
>AJ223948-1|CAA11679.1| 1257|Homo sapiens RNA helicase protein.
Length = 1257
Score = 86.2 bits (204), Expect = 8e-16
Identities = 50/182 (27%), Positives = 99/182 (54%), Gaps = 9/182 (4%)
Query: 130 ANLVYSAPTSAGKTLVAEILTIKTVLERQ-KKVIIILPFVSIVREKMF-YLQNILSSSGI 187
+N++ APT +GKT+ AE+ + + K + I P ++VRE+M + I G
Sbjct: 407 SNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGK 466
Query: 188 RVEGFMGSQSP-AGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQN 246
+V G +P + + + T EK + + + ++ + +++DE+HLLG++
Sbjct: 467 KVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEE- 525
Query: 247 RGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAEL-----FITTFRPIP 301
RG +LE+++++ +++S ++ ++++G+S L N LA WLN + F + RP+P
Sbjct: 526 RGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVP 585
Query: 302 LE 303
LE
Sbjct: 586 LE 587
Score = 74.5 bits (175), Expect = 3e-12
Identities = 51/156 (32%), Positives = 79/156 (50%), Gaps = 9/156 (5%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L+ T++FG+G HHAGL +R +E F + ++VL+ATSTL+ GVN PA VII+
Sbjct: 669 DSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKG 728
Query: 469 PVF------QKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ + I QM GRAGR D +G+++++ + +K +
Sbjct: 729 TEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVE 788
Query: 523 KSCIETKEKYMRAILEIIASNISCSKQELLLYTDCT 558
S + ++ A EI I+ SKQ+ L Y T
Sbjct: 789 SSLLGVLSDHLNA--EIAGGTIT-SKQDALDYITWT 821
>AB209605-1|BAD92842.1| 607|Homo sapiens DJ34F7.7 (Superkiller
viralicidic activity 2 -like variant protein.
Length = 607
Score = 79.8 bits (188), Expect = 7e-14
Identities = 58/183 (31%), Positives = 92/183 (50%), Gaps = 17/183 (9%)
Query: 350 VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLD 409
V++F ++ RC+ A L+S E SE + L+ L +L+ S L
Sbjct: 145 VVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQ---------RCLARLRGSDRQLP 195
Query: 410 QILQKT--ISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIR 467
Q+L + ++ G+G HH+G+ ++I+E F G ++VL AT T + GVN+PAR V+
Sbjct: 196 QVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFD 255
Query: 468 SPVFQKQPI--NIL--SYKQMSGRAGRMGRDTKGESILICSEAEKKIG--FNLMMGDLDP 521
S ++L Y QM+GRAGR G D G IL+C ++ +MMG
Sbjct: 256 SMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQ 315
Query: 522 VKS 524
++S
Sbjct: 316 LQS 318
>BC014669-1|AAH14669.2| 706|Homo sapiens SKIV2L2 protein protein.
Length = 706
Score = 79.0 bits (186), Expect = 1e-13
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 16/197 (8%)
Query: 350 VLIFCMTKNRCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLD 409
V+IF +K CE+ A ++ +F ++ E A++ L + L
Sbjct: 53 VIIFSFSKKDCEAYALQMTKL---------DFNTDEEKKMVEEVFSNAIDCLSDEDKKLP 103
Query: 410 QI--LQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVII- 466
Q+ + + G+G HH GL ++ IE F G I+ L AT T + G+N+PAR V+
Sbjct: 104 QVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFT 163
Query: 467 RSPVFQKQPINILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGFNLMMGDLDPV 522
+ F + +S Y QMSGRAGR G D +G IL+ E IG L+ G DP+
Sbjct: 164 NARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPL 223
Query: 523 KSCIETKEKYMRAILEI 539
S + +L +
Sbjct: 224 NSAFHLTYNMVLNLLRV 240
>BC038115-1|AAH38115.1| 1712|Homo sapiens hypothetical protein
FLJ20035 protein.
Length = 1712
Score = 77.4 bits (182), Expect = 4e-13
Identities = 34/81 (41%), Positives = 57/81 (70%), Gaps = 5/81 (6%)
Query: 419 GVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVII-RSPVFQKQPIN 477
G+GYHH+ ++ E+ ++E F+ G +RV+ AT TL+ GVN+P + V+ ++ V+ ++
Sbjct: 1260 GIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSVY----LD 1315
Query: 478 ILSYKQMSGRAGRMGRDTKGE 498
L+Y+QMSGRAGR G+D G+
Sbjct: 1316 ALNYRQMSGRAGRRGQDLMGD 1336
Score = 35.1 bits (77), Expect = 1.9
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 14/162 (8%)
Query: 133 VYSAPTSAGKTLVAEILTIKTVLERQKKVII-ILPFVSIVREKMFYLQNILSSSGIRVEG 191
V APTS+GKT + K + E V++ + P ++V + +QN + + E
Sbjct: 782 VIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEV 841
Query: 192 FMG--SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN-IEDLGAVVVDELHLLGDQNRG 248
G ++ N V I T+ ++ N ++ + V+ DE+H LG +
Sbjct: 842 LCGVFTREYRHDALNCQVLI-TVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA 900
Query: 249 YILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNA 290
I E LL I+ + +SAT+ N E L WL +
Sbjct: 901 EIWEHLLVMIR---------CPFLALSATISNPEHLTEWLQS 933
>BC031779-1|AAH31779.1| 596|Homo sapiens SKIV2L2 protein protein.
Length = 596
Score = 75.8 bits (178), Expect = 1e-12
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Query: 419 GVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVII-RSPVFQKQPIN 477
G+G HH GL ++ IE F G I+ L AT T + G+N+PAR V+ + F +
Sbjct: 5 GIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFR 64
Query: 478 ILS---YKQMSGRAGRMGRDTKGESILICSE-AEKKIGFNLMMGDLDPVKSCIETKEKYM 533
+S Y QMSGRAGR G D +G IL+ E IG L+ G DP+ S +
Sbjct: 65 WISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMV 124
Query: 534 RAILEI 539
+L +
Sbjct: 125 LNLLRV 130
>BC132823-1|AAI32824.1| 471|Homo sapiens HFM1 protein protein.
Length = 471
Score = 73.3 bits (172), Expect = 6e-12
Identities = 64/263 (24%), Positives = 122/263 (46%), Gaps = 24/263 (9%)
Query: 45 SENKQKHVNRRFVNTASNNSLLNKTAEGKLTASK-----EVRNTQKIQSKKLKDWGLPIE 99
S +KQK V TA+N ++ EG A + + Q++ L E
Sbjct: 207 SNSKQKFQYSANVFTANNAFSASEIGEGMFKAPSFSVAFQPHDIQEVTENGLGSLKAVTE 266
Query: 100 ISKKYEERGITEMFDW--QLACLCNTKVLFDCANLVYSAPTSAGKTLVAEILTIKTVLE- 156
I K+ R I + F + + +L+ N V APT +GKT+V E+ + ++E
Sbjct: 267 IPAKF--RSIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEV 324
Query: 157 ----RQKKVIIILPFVSIVREKMFYLQNILSSSGIRVEGFMGS--QSPAGGMQNVHVAIC 210
K++ + P ++ ++ + G+ + G +Q+ H+ +
Sbjct: 325 PLPWLNIKIVYMAPIKALCSQRFDDWKEKFGPIGLNCKELTGDTVMDDLFEIQHAHIIMT 384
Query: 211 TIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGYILELLLTKIKYVTSKSDLL-- 268
T EK +SM + DN ++ + ++DE+H++ D+NRG LE++++++K V S S L
Sbjct: 385 TPEKWDSMTRKWRDNSLVQLVRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKN 444
Query: 269 ------IQVIGMSATLPNLETLA 285
++ + +SAT+PN E ++
Sbjct: 445 TSTAIPMRFVAVSATIPNAEDVS 467
>BC131784-1|AAI31785.1| 595|Homo sapiens ASCC3L1 protein protein.
Length = 595
Score = 70.1 bits (164), Expect = 6e-11
Identities = 53/159 (33%), Positives = 83/159 (52%), Gaps = 11/159 (6%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L++T+ GVGY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII
Sbjct: 65 DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMD 124
Query: 469 PVFQKQPIN------ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ I+ I QM G A R +D +G +++C + KK F + + PV
Sbjct: 125 TQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPV 183
Query: 523 KSCIE-TKEKYMRAILEIIASNISCSKQELLLYTDCTLL 560
+S ++ + A EI+ I +KQ+ + Y T L
Sbjct: 184 ESHLDHCMHDHFNA--EIVTKTIE-NKQDAVDYLTWTFL 219
>AF085356-1|AAD40191.1| 595|Homo sapiens putative RNA helicase
protein.
Length = 595
Score = 70.1 bits (164), Expect = 6e-11
Identities = 53/159 (33%), Positives = 83/159 (52%), Gaps = 11/159 (6%)
Query: 409 DQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRS 468
D L++T+ GVGY H GL+ ER ++E F SGAI+V+VA+ +L G+N+ A VII
Sbjct: 65 DSTLKETLLNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMD 124
Query: 469 PVFQKQPIN------ILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPV 522
+ I+ I QM G A R +D +G +++C + KK F + + PV
Sbjct: 125 TQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMC-QGSKKDFFKKFLYEPLPV 183
Query: 523 KSCIE-TKEKYMRAILEIIASNISCSKQELLLYTDCTLL 560
+S ++ + A EI+ I +KQ+ + Y T L
Sbjct: 184 ESHLDHCMHDHFNA--EIVTKTIE-NKQDAVDYLTWTFL 219
>BC026066-1|AAH26066.1| 731|Homo sapiens ASCC3 protein protein.
Length = 731
Score = 64.9 bits (151), Expect = 2e-09
Identities = 48/189 (25%), Positives = 92/189 (48%), Gaps = 18/189 (9%)
Query: 131 NLVYSAPTSAGKTLVAEILTIKTVLER---------QKKVIIILPFVSIVREKMFYLQNI 181
N++ APT AGKT +A + + + + + K++ + P ++ E Y
Sbjct: 494 NMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRR 553
Query: 182 LSSSGIRVEGFMGS-QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDL-GAVVVDEL 239
L GI V+ G Q + + T EK + + + + + + + +++DE+
Sbjct: 554 LEPLGIIVKELTGDMQLSKSEILRTQMLATTPEKWDVVTRKSVGDVALSQIVRLLILDEV 613
Query: 240 HLLGDQNRGYILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFI----- 294
HLL ++RG +LE ++ + + +I+++G+SATLPN +AT+L+ +I
Sbjct: 614 HLL-HEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFF 672
Query: 295 -TTFRPIPL 302
FRP+PL
Sbjct: 673 DGRFRPVPL 681
>D30655-1|BAA06336.1| 407|Homo sapiens eukaryotic initiation factor
4AII protein.
Length = 407
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 298 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 353
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 354 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 384
>BT009860-1|AAP88862.1| 407|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 2 protein.
Length = 407
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 298 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 353
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 354 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 384
>BC048105-1|AAH48105.1| 408|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 2 protein.
Length = 408
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 299 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 354
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 355 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 385
>BC016295-1|AAH16295.1| 179|Homo sapiens EIF4A2 protein protein.
Length = 179
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 70 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 125
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 126 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 156
>BC015842-1|AAH15842.1| 407|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 2 protein.
Length = 407
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 298 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 353
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 354 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 384
>BC013708-1|AAH13708.1| 407|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 2 protein.
Length = 407
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 298 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 353
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 354 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 384
>BC012547-1|AAH12547.1| 408|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 2 protein.
Length = 408
Score = 51.6 bits (118), Expect = 2e-05
Identities = 32/93 (34%), Positives = 49/93 (52%), Gaps = 6/93 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 299 FTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 354
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKKI 510
+Y GR GR GR KG +I +E +K+I
Sbjct: 355 RENYIHRIGRGGRFGR--KGVAINFVTEEDKRI 385
>D13748-1|BAA02897.1| 406|Homo sapiens eukaryotic initiation factor
4AI protein.
Length = 406
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 352
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 353 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 382
>BT019881-1|AAV38684.1| 406|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 1 protein.
Length = 406
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 352
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 353 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 382
>BT019880-1|AAV38683.1| 406|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 1 protein.
Length = 406
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 352
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 353 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 382
>BC073752-1|AAH73752.1| 406|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 1 protein.
Length = 406
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 352
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 353 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 382
>BC009585-1|AAH09585.1| 406|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 1 protein.
Length = 406
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 297 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 352
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 353 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 382
>BC006380-1|AAH06380.1| 473|Homo sapiens Unknown (protein for
IMAGE:4099962) protein.
Length = 473
Score = 50.8 bits (116), Expect = 4e-05
Identities = 31/92 (33%), Positives = 49/92 (53%), Gaps = 6/92 (6%)
Query: 418 FGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
F V H + ERD+I F+SG+ RVL+ T L+ G+++ ++I + P N
Sbjct: 364 FTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDL----PTN 419
Query: 478 ILSYKQMSGRAGRMGRDTKGESILICSEAEKK 509
+Y GR GR GR KG +I + +E +K+
Sbjct: 420 RENYIHRIGRGGRFGR--KGVAINMVTEEDKR 449
>BC018637-1|AAH18637.2| 423|Homo sapiens DDX50 protein protein.
Length = 423
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 105 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 160
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 161 RSGRTGRAGR 170
>BC000272-1|AAH00272.1| 737|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 50 protein.
Length = 737
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 474
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 475 RSGRTGRAGR 484
>BC000210-1|AAH00210.1| 467|Homo sapiens DDX50 protein protein.
Length = 467
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 149 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 204
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 205 RSGRTGRAGR 214
>AL359844-2|CAH72376.1| 737|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 50 protein.
Length = 737
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 474
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 475 RSGRTGRAGR 484
>AL137423-1|CAB70733.1| 399|Homo sapiens hypothetical protein
protein.
Length = 399
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 81 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 136
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 137 RSGRTGRAGR 146
>AF334103-1|AAK29402.1| 737|Homo sapiens nucleolar protein GU2
protein.
Length = 737
Score = 47.2 bits (107), Expect = 4e-04
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F+ G+ +VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 419 HGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQS----SPPQDVESYIH 474
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 475 RSGRTGRAGR 484
>U41387-1|AAB02546.1| 801|Homo sapiens Gu protein protein.
Length = 801
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F++G+ VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 486 HGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQS----SPPKDVESYIH 541
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 542 RSGRTGRAGR 551
>BC008071-1|AAH08071.2| 783|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 21 protein.
Length = 783
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F++G+ VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 468 HGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQS----SPPKDVESYIH 523
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 524 RSGRTGRAGR 533
>AL359844-3|CAH72377.1| 783|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 21 protein.
Length = 783
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F++G+ VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 468 HGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQS----SPPKDVESYIH 523
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 524 RSGRTGRAGR 533
>AF261917-1|AAF78930.2| 715|Homo sapiens RNA helicase II/Gu protein
protein.
Length = 715
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/70 (34%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H + +R+I F++G+ VLVAT+ + G+++P ++I+S P ++ SY
Sbjct: 400 HGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQS----SPPKDVESYIH 455
Query: 484 MSGRAGRMGR 493
SGR GR GR
Sbjct: 456 RSGRTGRAGR 465
>AY044431-1|AAK95821.1| 796|Homo sapiens RNA helicase-like protein
protein.
Length = 796
Score = 44.8 bits (101), Expect = 0.002
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 362 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 421
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 422 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 475
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 476 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 534
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 535 VINFTM----PNTIKHYDHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 588
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 589 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 646
>AK022979-1|BAB14343.1| 765|Homo sapiens protein ( Homo sapiens
cDNA FLJ12917 fis, clone NT2RP2004568, weakly similar to
PUTATIVE ATP-DEPENDENT RNA HELICASE C30D11.03. ).
Length = 765
Score = 44.8 bits (101), Expect = 0.002
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 331 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 390
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 391 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 444
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 445 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 503
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 504 VINFTM----PNTIKHYDHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 557
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 558 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 615
>BC130275-1|AAI30276.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 27 protein.
Length = 796
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 362 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 421
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 422 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 475
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 476 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 534
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 535 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 588
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 589 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 646
>BC126287-1|AAI26288.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 27 protein.
Length = 796
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 362 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 421
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 422 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 475
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 476 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 534
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 535 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 588
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 589 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 646
>BC016060-1|AAH16060.2| 767|Homo sapiens DDX27 protein protein.
Length = 767
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 333 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 392
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 393 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 446
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 447 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 505
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 506 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 559
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 560 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 617
>BC011927-1|AAH11927.2| 767|Homo sapiens DDX27 protein protein.
Length = 767
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 333 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 392
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 393 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 446
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 447 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 505
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 506 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 559
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 560 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 617
>BC009304-1|AAH09304.2| 769|Homo sapiens DDX27 protein protein.
Length = 769
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 335 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 394
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 395 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 448
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 449 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 507
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 508 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 561
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 562 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 619
>AL357560-1|CAH70236.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 27 protein.
Length = 796
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 362 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 421
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 422 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 475
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 476 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 534
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 535 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 588
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 589 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 646
>AL049766-1|CAI22427.1| 796|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 27 protein.
Length = 796
Score = 44.4 bits (100), Expect = 0.003
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 35/298 (11%)
Query: 294 ITTFRPIPLEEYCLVENKYYDKNGKYILEAKSSN-----YGVSCNDSVLKICLETIKEGC 348
+++ + L+E + ++Y+++ K I+ S + + + D V + ++K
Sbjct: 362 LSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPV 421
Query: 349 SVLIFCMTKNRCESLAQLLSSTFCKI--GCEGSEFGMI--LRSQLNSEHILEALEQLKNS 404
+ + N +A L F +I EG ++ L ++ ++H++ Q K
Sbjct: 422 RIFV-----NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVM-LFTQTKKQ 475
Query: 405 PVGLDQILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKV 464
+ IL + VG H L+ +R FK I +LVAT + G+++ K
Sbjct: 476 AHRM-HILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKT 534
Query: 465 IIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS 524
+I + P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 535 VINFTM----PNTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKA 588
Query: 525 -------------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 589 RILPQDVILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 646
>DQ176868-1|AAZ85145.1| 1208|Homo sapiens RecQ protein-like 4
protein.
Length = 1208
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAG+ ER ++ AF G +RV+VAT G++ P +R+ + P + SY
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD----VRAVLHLGLPPSFESYV 799
Query: 483 QMSGRAGRMGR 493
Q GRAGR G+
Sbjct: 800 QAVGRAGRDGQ 810
>BC013277-1|AAH13277.2| 652|Homo sapiens RECQL4 protein protein.
Length = 652
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAG+ ER ++ AF G +RV+VAT G++ P +R+ + P + SY
Sbjct: 188 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD----VRAVLHLGLPPSFESYV 243
Query: 483 QMSGRAGRMGR 493
Q GRAGR G+
Sbjct: 244 QAVGRAGRDGQ 254
>BC011602-1|AAH11602.2| 741|Homo sapiens RECQL4 protein protein.
Length = 741
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAG+ ER ++ AF G +RV+VAT G++ P +R+ + P + SY
Sbjct: 277 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD----VRAVLHLGLPPSFESYV 332
Query: 483 QMSGRAGRMGR 493
Q GRAGR G+
Sbjct: 333 QAVGRAGRDGQ 343
>AK223116-1|BAD96836.1| 408|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 27 variant protein.
Length = 408
Score = 44.0 bits (99), Expect = 0.004
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 19/172 (11%)
Query: 411 ILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPV 470
IL + VG H L+ +R FK I +LVAT + G+++ K +I +
Sbjct: 93 ILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM 152
Query: 471 FQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS------ 524
P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 153 ----PSTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQD 206
Query: 525 -------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 207 VILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 258
>AK000603-1|BAA91284.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ20596 fis, clone KAT08049. ).
Length = 406
Score = 44.0 bits (99), Expect = 0.004
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 19/172 (11%)
Query: 411 ILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPV 470
IL + VG H L+ +R FK I +LVAT + G+++ K +I +
Sbjct: 91 ILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM 150
Query: 471 FQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS------ 524
P I Y GR R GR G S+ + E E+K+ ++ PVK+
Sbjct: 151 ----PSTIKHYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQD 204
Query: 525 -------CIETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
IE EK + A+L++ A + E + T LL KE + Q
Sbjct: 205 VILKFRDKIEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 256
>AB026546-1|BAA86899.1| 1208|Homo sapiens RECQL4 helicase protein.
Length = 1208
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAG+ ER ++ AF G +RV+VAT G++ P +R+ + P + SY
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD----VRAVLHLGLPPSFESYV 799
Query: 483 QMSGRAGRMGR 493
Q GRAGR G+
Sbjct: 800 QAVGRAGRDGQ 810
>AB006532-1|BAA74453.1| 1208|Homo sapiens DNA helicase protein.
Length = 1208
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAG+ ER ++ AF G +RV+VAT G++ P +R+ + P + SY
Sbjct: 744 YHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPD----VRAVLHLGLPPSFESYV 799
Query: 483 QMSGRAGRMGR 493
Q GRAGR G+
Sbjct: 800 QAVGRAGRDGQ 810
>D21853-1|BAA04879.2| 412|Homo sapiens KIAA0111 protein.
Length = 412
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 302 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 357
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+GR GR KG +I
Sbjct: 358 NRELYIHRIGRSGRYGR--KGVAI 379
>CR456750-1|CAG33031.1| 411|Homo sapiens DDX48 protein.
Length = 411
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 356
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+GR GR KG +I
Sbjct: 357 NRELYIHRIGRSGRYGR--KGVAI 378
>BC011151-1|AAH11151.1| 411|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 3 protein.
Length = 411
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 356
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+GR GR KG +I
Sbjct: 357 NRELYIHRIGRSGRYGR--KGVAI 378
>BC004386-1|AAH04386.1| 411|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 3 protein.
Length = 411
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 356
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+GR GR KG +I
Sbjct: 357 NRELYIHRIGRSGRYGR--KGVAI 378
>BC003662-1|AAH03662.1| 411|Homo sapiens eukaryotic translation
initiation factor 4A, isoform 3 protein.
Length = 411
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 356
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+GR GR KG +I
Sbjct: 357 NRELYIHRIGRSGRYGR--KGVAI 378
>AF336851-1|AAK21271.1| 561|Homo sapiens RNA helicase-like protein
protein.
Length = 561
Score = 42.7 bits (96), Expect = 0.010
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 19/163 (11%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
VG H L+ +R FK I +LVAT + G+++ K +I + P I
Sbjct: 255 VGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTM----PNTIK 310
Query: 480 SYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKS-------------CI 526
Y GR R GR G S+ + E E+K+ ++ PVK+ I
Sbjct: 311 HYVHRVGRTARAGR--AGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKI 368
Query: 527 ETKEKYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEILSQ 569
E EK + A+L++ A + E + T LL KE + Q
Sbjct: 369 EKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQ 411
>X79538-1|CAA56074.1| 411|Homo sapiens translation initiation
factor protein.
Length = 411
Score = 41.9 bits (94), Expect = 0.017
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 6/84 (7%)
Query: 417 SFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPI 476
+F V H + ER+ I F+SGA RVL++T + G+++P +II + P
Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PN 356
Query: 477 NILSYKQMSGRAGRMGRDTKGESI 500
N Y GR+G+ GR KG +I
Sbjct: 357 NRELYIHRIGRSGQYGR--KGVAI 378
>L76937-1|AAC41981.1| 1432|Homo sapiens protein ( Homo sapiens
Werner syndrome gene, complete cds. ).
Length = 1432
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 785 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 840
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 841 APKDMESYYQEIGRAGRDG 859
>AY818673-1|AAX21098.1| 1432|Homo sapiens Werner syndrome helicase
protein.
Length = 1432
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 785 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 840
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 841 APKDMESYYQEIGRAGRDG 859
>AY442327-1|AAR05448.1| 1432|Homo sapiens Werner syndrome protein.
Length = 1432
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 785 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 840
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 841 APKDMESYYQEIGRAGRDG 859
>AF181897-1|AAF06162.1| 1432|Homo sapiens WRN protein.
Length = 1432
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 785 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 840
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 841 APKDMESYYQEIGRAGRDG 859
>AF091214-1|AAC63361.1| 1432|Homo sapiens WRN protein.
Length = 1432
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 785 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 840
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 841 APKDMESYYQEIGRAGRDG 859
>AB209652-1|BAD92889.1| 842|Homo sapiens Werner syndrome protein
variant protein.
Length = 842
Score = 41.5 bits (93), Expect = 0.022
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ ++ G +HAG++ R I F I+ ++AT G+N K IR +
Sbjct: 195 RKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGIN----KADIRQVIHYG 250
Query: 474 QPINILSYKQMSGRAGRMG 492
P ++ SY Q GRAGR G
Sbjct: 251 APKDMESYYQEIGRAGRDG 269
>BC041785-1|AAH41785.1| 599|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 52 protein.
Length = 599
Score = 41.1 bits (92), Expect = 0.029
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
HA T +RD +F++G I VL+ T+ L+ G++ ++I P + + Y
Sbjct: 443 HAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF----PTSSVEYIH 498
Query: 484 MSGRAGRMGRDTKGESILICSEAEKKI 510
GR GR G KG++I +E +K +
Sbjct: 499 RIGRTGRAG--NKGKAITFFTEDDKPL 523
>BC002366-1|AAH02366.1| 820|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 23 protein.
Length = 820
Score = 41.1 bits (92), Expect = 0.029
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 403 NSPVGLDQILQKTISFGVGYH----HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVN 458
N G D +L K++ +GY+ H G ++R+ K+GA +LVAT G++
Sbjct: 672 NQKKGCD-VLAKSLE-KMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGID 729
Query: 459 LPARKVIIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGD 518
+ +++ + + NI Y GR GR G+ G +I ++ + + + L
Sbjct: 730 IQDVSMVVNYDMAK----NIEDYIHRIGRTGRAGK--SGVAITFLTKEDSAVFYELKQAI 783
Query: 519 LD-PVKSC 525
L+ PV SC
Sbjct: 784 LESPVSSC 791
>AK001652-1|BAA91812.1| 491|Homo sapiens protein ( Homo sapiens
cDNA FLJ10790 fis, clone NT2RP4000518, weakly similar to
ATP-DEPENDENT RNA HELICASE ROK1. ).
Length = 491
Score = 41.1 bits (92), Expect = 0.029
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
HA T +RD +F++G I VL+ T+ L+ G++ ++I P + + Y
Sbjct: 335 HAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF----PTSSVEYIH 390
Query: 484 MSGRAGRMGRDTKGESILICSEAEKKI 510
GR GR G KG++I +E +K +
Sbjct: 391 RIGRTGRAG--NKGKAITFFTEDDKPL 415
>AJ010840-1|CAA09374.1| 420|Homo sapiens ATP-dependent RNA helicase
protein.
Length = 420
Score = 41.1 bits (92), Expect = 0.029
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
HA T +RD +F++G I VL+ T+ L+ G++ ++I P + + Y
Sbjct: 264 HAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDF----PTSSVEYIH 319
Query: 484 MSGRAGRMGRDTKGESILICSEAEKKI 510
GR GR G KG++I +E +K +
Sbjct: 320 RIGRTGRAG--NKGKAITFFTEDDKPL 344
>AF026402-1|AAB87902.1| 820|Homo sapiens U5 snRNP 100 kD protein
protein.
Length = 820
Score = 41.1 bits (92), Expect = 0.029
Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 403 NSPVGLDQILQKTISFGVGYH----HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVN 458
N G D +L K++ +GY+ H G ++R+ K+GA +LVAT G++
Sbjct: 672 NQKKGCD-VLAKSLE-KMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGID 729
Query: 459 LPARKVIIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGD 518
+ +++ + + NI Y GR GR G+ G +I ++ + + + L
Sbjct: 730 IQDVSMVVNYDMAK----NIEDYIHRIGRTGRAGK--SGVAITFLTKEDSAVFYELKQAI 783
Query: 519 LD-PVKSC 525
L+ PV SC
Sbjct: 784 LESPVSSC 791
>BC002674-1|AAH02674.1| 483|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 49 protein.
Length = 483
Score = 40.3 bits (90), Expect = 0.051
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 12/172 (6%)
Query: 411 ILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPV 470
++ + SF H+ + ER FKS R+L+AT S G+++P +V+I
Sbjct: 266 MMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVIN--- 322
Query: 471 FQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKE 530
P Y GR R GR +G++I + ++ + +L+ + +K +E
Sbjct: 323 -HNTPGLPKIYIHRVGRTARAGR--QGQAITLVTQYD----IHLVHAIEEQIKKKLEEFS 375
Query: 531 KYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEI-LSQNLILEDTLKELE 581
+L+I+ + ++ ++E + + +KEI + LILE +LE
Sbjct: 376 VEEAEVLQIL-TQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPDLE 426
>AK223294-1|BAD97014.1| 483|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 49 variant protein.
Length = 483
Score = 40.3 bits (90), Expect = 0.051
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 12/172 (6%)
Query: 411 ILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPV 470
++ + SF H+ + ER FKS R+L+AT S G+++P +V+I
Sbjct: 266 MMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVIN--- 322
Query: 471 FQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKE 530
P Y GR R GR +G++I + ++ + +L+ + +K +E
Sbjct: 323 -HNTPGLPKIYIHRVGRTARAGR--QGQAITLVTQYD----IHLVHAIEEQIKKKLEEFS 375
Query: 531 KYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEI-LSQNLILEDTLKELE 581
+L+I+ + ++ ++E + + +KEI + LILE +LE
Sbjct: 376 VEEAEVLQIL-TQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPDLE 426
>AC002985-2|AAB81544.1| 483|Homo sapiens R27090_2 protein.
Length = 483
Score = 40.3 bits (90), Expect = 0.051
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 12/172 (6%)
Query: 411 ILQKTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPV 470
++ + SF H+ + ER FKS R+L+AT S G+++P +V+I
Sbjct: 266 MMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASRGLDIPTVQVVIN--- 322
Query: 471 FQKQPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKE 530
P Y GR R GR +G++I + ++ + +L+ + +K +E
Sbjct: 323 -HNTPGLPKIYIHRVGRTARAGR--QGQAITLVTQYD----IHLVHAIEEQIKKKLEEFS 375
Query: 531 KYMRAILEIIASNISCSKQELLLYTDCTLLSAQKEI-LSQNLILEDTLKELE 581
+L+I+ + ++ ++E + + +KEI + LILE +LE
Sbjct: 376 VEEAEVLQIL-TQVNVVRRECEIKLEAAHFDEKKEINKRKQLILEGKDPDLE 426
>L36140-1|AAA60261.1| 659|Homo sapiens DNA helicase protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.16
Identities = 35/141 (24%), Positives = 68/141 (48%), Gaps = 19/141 (13%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ + G +HA L +++ + + + I+V+VAT G++ P + +I + +
Sbjct: 335 QNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSK- 393
Query: 474 QPINILSYKQMSGRAGRMGRDTKGESILICSEAEKKIGFNLMMGDLDPVKSCIETKEKYM 533
++ +Y Q SGRAGR D K + IL GF GD+ + S + +
Sbjct: 394 ---SMENYYQESGRAGR--DDMKADCILY-------YGF----GDIFRISSMVVMENVGQ 437
Query: 534 RAILEIIA--SNISCSKQELL 552
+ + E+++ NIS S++ L+
Sbjct: 438 QKLYEMVSYCQNISKSRRVLM 458
>D37984-1|BAA07200.1| 649|Homo sapiens DNA helicase Q1 protein.
Length = 649
Score = 38.3 bits (85), Expect = 0.21
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ + G +HA L +++ + + + I+V+VAT G++ P + +I + +
Sbjct: 335 QNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSK- 393
Query: 474 QPINILSYKQMSGRAGRMGRDTKGESIL 501
++ +Y Q SGRAGR D K + IL
Sbjct: 394 ---SMENYYQESGRAGR--DDMKADCIL 416
>BT007119-1|AAP35783.1| 649|Homo sapiens RecQ protein-like (DNA
helicase Q1-like) protein.
Length = 649
Score = 38.3 bits (85), Expect = 0.21
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ + G +HA L +++ + + + I+V+VAT G++ P + +I + +
Sbjct: 335 QNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSK- 393
Query: 474 QPINILSYKQMSGRAGRMGRDTKGESIL 501
++ +Y Q SGRAGR D K + IL
Sbjct: 394 ---SMENYYQESGRAGR--DDMKADCIL 416
>BC063440-1|AAH63440.1| 964|Homo sapiens RecQ protein-like 5
protein.
Length = 964
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 262 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 317
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 318 QESGRAGRDGK 328
>BC016911-1|AAH16911.1| 435|Homo sapiens RECQL5 protein protein.
Length = 435
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>BC001052-1|AAH01052.1| 649|Homo sapiens RecQ protein-like (DNA
helicase Q1-like) protein.
Length = 649
Score = 38.3 bits (85), Expect = 0.21
Identities = 24/88 (27%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 414 KTISFGVGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQK 473
+ + G +HA L +++ + + + I+V+VAT G++ P + +I + +
Sbjct: 335 QNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSK- 393
Query: 474 QPINILSYKQMSGRAGRMGRDTKGESIL 501
++ +Y Q SGRAGR D K + IL
Sbjct: 394 ---SMENYYQESGRAGR--DDMKADCIL 416
>AF135183-2|AAD43062.1| 410|Homo sapiens Recq helicase 5 protein.
Length = 410
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>AF135183-1|AAD43061.1| 435|Homo sapiens Recq helicase 5 protein.
Length = 435
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>AB042825-1|BAA95954.1| 435|Homo sapiens DNA helicase recQ5 gamma
protein.
Length = 435
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>AB042824-1|BAA95953.1| 991|Homo sapiens DNA helicase recQ5 beta
protein.
Length = 991
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>AB042823-1|BAA95952.1| 410|Homo sapiens DNA helicase recQ5 alpha
protein.
Length = 410
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>AB006533-1|BAA74454.1| 410|Homo sapiens DNA helicase protein.
Length = 410
Score = 38.3 bits (85), Expect = 0.21
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Query: 423 HHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYK 482
+HAGL ER +++ + + V+VAT + GV+ K +R ++ Y
Sbjct: 289 YHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVD----KANVRFVAHWNIAKSMAGYY 344
Query: 483 QMSGRAGRMGR 493
Q SGRAGR G+
Sbjct: 345 QESGRAGRDGK 355
>BX641072-1|CAE46035.1| 496|Homo sapiens hypothetical protein
protein.
Length = 496
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 337 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 392
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 393 RIGRTGRSG 401
>BC015476-1|AAH15476.1| 622|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 41 protein.
Length = 622
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 463 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 518
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 519 RIGRTGRSG 527
>AL137455-1|CAB70746.1| 240|Homo sapiens hypothetical protein
protein.
Length = 240
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 81 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 136
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 137 RIGRTGRSG 145
>AK222598-1|BAD96318.1| 622|Homo sapiens DEAD-box protein abstrakt
variant protein.
Length = 622
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 463 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 518
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 519 RIGRTGRSG 527
>AK027768-1|BAB55355.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ14862 fis, clone PLACE1001739, weakly similar to
PUTATIVE ATP-DEPENDENT RNA HELICASE PL10. ).
Length = 622
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 463 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 518
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 519 RIGRTGRSG 527
>AK001255-1|BAA91585.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ10393 fis, clone NT2RM4000191, weakly similar to
PUTATIVE ATP-DEPENDENT RNA HELICASE PL10. ).
Length = 622
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 463 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 518
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 519 RIGRTGRSG 527
>AF195417-1|AAF04150.1| 621|Homo sapiens DEAD-box protein abstrakt
protein.
Length = 621
Score = 37.9 bits (84), Expect = 0.27
Identities = 25/69 (36%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G +ER AF+ G VLVAT S G++ PA I+ + P I +Y
Sbjct: 462 HGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPA----IQHVINYDMPEEIENYVH 517
Query: 484 MSGRAGRMG 492
GR GR G
Sbjct: 518 RIGRTGRSG 526
>BC093081-1|AAH93081.1| 938|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 42 protein.
Length = 938
Score = 36.7 bits (81), Expect = 0.63
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
+G H + ER+ + FK I VLVAT + G+++P+ K +I V + +I
Sbjct: 525 LGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR----DID 580
Query: 480 SYKQMSGRAGRMG 492
++ GR GR G
Sbjct: 581 THTHRIGRTGRAG 593
>BC078667-1|AAH78667.1| 919|Homo sapiens DDX42 protein protein.
Length = 919
Score = 36.7 bits (81), Expect = 0.63
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
+G H + ER+ + FK I VLVAT + G+++P+ K +I V + +I
Sbjct: 506 LGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR----DID 561
Query: 480 SYKQMSGRAGRMG 492
++ GR GR G
Sbjct: 562 THTHRIGRTGRAG 574
>BC015505-1|AAH15505.1| 819|Homo sapiens DDX42 protein protein.
Length = 819
Score = 36.7 bits (81), Expect = 0.63
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
+G H + ER+ + FK I VLVAT + G+++P+ K +I V + +I
Sbjct: 406 LGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR----DID 461
Query: 480 SYKQMSGRAGRMG 492
++ GR GR G
Sbjct: 462 THTHRIGRTGRAG 474
>BC012304-1|AAH12304.1| 1031|Homo sapiens DEAD (Asp-Glu-Ala-Asp) box
polypeptide 46 protein.
Length = 1031
Score = 36.7 bits (81), Expect = 0.63
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G+ +RD I FK+G ++LVATS + G+++ +++ P + Y
Sbjct: 650 HGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVN----YSCPNHYEDYVH 705
Query: 484 MSGRAGRMGRDTKGESILICSEAEKK 509
+GR GR G KG + +E + +
Sbjct: 706 RAGRTGRAG--NKGYAYTFITEDQAR 729
>AF106680-1|AAD43033.1| 1031|Homo sapiens RNA helicase protein.
Length = 1031
Score = 36.7 bits (81), Expect = 0.63
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G+ +RD I FK+G ++LVATS + G+++ +++ P + Y
Sbjct: 649 HGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVN----YSCPNHYEDYVH 704
Query: 484 MSGRAGRMGRDTKGESILICSEAEKK 509
+GR GR G KG + +E + +
Sbjct: 705 RAGRTGRAG--NKGYAYTFITEDQAR 728
>AF083255-1|AAC32396.1| 709|Homo sapiens RNA helicase-related
protein protein.
Length = 709
Score = 36.7 bits (81), Expect = 0.63
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
+G H + ER+ + FK I VLVAT + G+++P+ K +I V + +I
Sbjct: 406 LGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR----DID 461
Query: 480 SYKQMSGRAGRMG 492
++ GR GR G
Sbjct: 462 THTHRIGRTGRAG 474
>AB036090-1|BAC66466.1| 938|Homo sapiens RNA helicase-related
protein protein.
Length = 938
Score = 36.7 bits (81), Expect = 0.63
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 4/73 (5%)
Query: 420 VGYHHAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINIL 479
+G H + ER+ + FK I VLVAT + G+++P+ K +I V + +I
Sbjct: 525 LGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVAR----DID 580
Query: 480 SYKQMSGRAGRMG 492
++ GR GR G
Sbjct: 581 THTHRIGRTGRAG 593
>AB018344-1|BAA34521.2| 1058|Homo sapiens KIAA0801 protein protein.
Length = 1058
Score = 36.7 bits (81), Expect = 0.63
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 424 HAGLTLDERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQ 483
H G+ +RD I FK+G ++LVATS + G+++ +++ P + Y
Sbjct: 676 HGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVN----YSCPNHYEDYVH 731
Query: 484 MSGRAGRMGRDTKGESILICSEAEKK 509
+GR GR G KG + +E + +
Sbjct: 732 RAGRTGRAG--NKGYAYTFITEDQAR 755
>BC014949-1|AAH14949.1| 678|Homo sapiens likely ortholog of mouse
D11lgp2 protein.
Length = 678
Score = 36.3 bits (80), Expect = 0.83
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Query: 359 RCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISF 418
+ E L ++L F S G+I S H L Q + +D Q I
Sbjct: 350 KLEMLEKILQRQFSS---SNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGA 406
Query: 419 GVGYHHAGLTL-DERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
G +T D++++I+ F+ G + +LVATS G+++P V++R + N
Sbjct: 407 GNSSQSTHMTQRDQQEVIQ-KFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLL----TN 461
Query: 478 ILSYKQMSGRA 488
+S Q GRA
Sbjct: 462 EISMVQARGRA 472
>AK021416-1|BAB13818.1| 678|Homo sapiens protein ( Homo sapiens
cDNA FLJ11354 fis, clone HEMBA1000129, weakly similar to
HYPOTHETICAL HELICASE C8A4.08C IN CHROMOSOME I. ).
Length = 678
Score = 36.3 bits (80), Expect = 0.83
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 9/131 (6%)
Query: 359 RCESLAQLLSSTFCKIGCEGSEFGMILRSQLNSEHILEALEQLKNSPVGLDQILQKTISF 418
+ E L ++L F S G+I S H L Q + +D Q I
Sbjct: 350 KLEMLEKILQRQFSS---SNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGA 406
Query: 419 GVGYHHAGLTL-DERDIIEGAFKSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPIN 477
G +T D++++I+ F+ G + +LVATS G+++P V++R + N
Sbjct: 407 GNSSQSTHMTQRDQQEVIQ-KFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLL----TN 461
Query: 478 ILSYKQMSGRA 488
+S Q GRA
Sbjct: 462 EISMVQARGRA 472
>BC001417-1|AAH01417.4| 494|Homo sapiens ASCC3L1 protein protein.
Length = 494
Score = 35.9 bits (79), Expect = 1.1
Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 11/122 (9%)
Query: 446 VLVATSTLSSGVNLPARKVIIRSPVFQKQPIN------ILSYKQMSGRAGRMGRDTKGES 499
V+VA+ +L G+N+ A VII + I+ I QM G A R +D +G
Sbjct: 1 VVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHANRPLQDDEGRC 60
Query: 500 ILICSEAEKKIGFNLMMGDLDPVKSCIE-TKEKYMRAILEIIASNISCSKQELLLYTDCT 558
+++C + KK F + + PV+S ++ + A EI+ I +KQ+ + Y T
Sbjct: 61 VIMC-QGSKKDFFKKFLYEPLPVESHLDHCMHDHFNA--EIVTKTIE-NKQDAVDYLTWT 116
Query: 559 LL 560
L
Sbjct: 117 FL 118
>U39817-1|AAA87850.1| 1417|Homo sapiens Bloom's syndrome protein
protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>BC115032-1|AAI15033.1| 1417|Homo sapiens Bloom syndrome protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>BC115030-1|AAI15031.1| 1417|Homo sapiens Bloom syndrome protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>BC101567-1|AAI01568.1| 1417|Homo sapiens Bloom syndrome protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>BC093622-1|AAH93622.1| 1417|Homo sapiens Bloom syndrome protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>AY886902-1|AAW62255.1| 1417|Homo sapiens Bloom syndrome protein.
Length = 1417
Score = 35.5 bits (78), Expect = 1.5
Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)
Query: 423 HHAGLTLDERDIIEGAF-KSGAIRVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSY 481
+HAGL+ RD ++ + +V+ AT G++ P + +I + + P ++ Y
Sbjct: 918 YHAGLSDSARDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASL----PKSVEGY 973
Query: 482 KQMSGRAGRMG 492
Q SGRAGR G
Sbjct: 974 YQESGRAGRDG 984
>BC036112-1|AAH36112.1| 786|Homo sapiens suppressor of var1, 3-like
1 (S. cerevisiae) protein.
Length = 786
Score = 35.1 bits (77), Expect = 1.9
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 445 RVLVATSTLSSGVNLPARKVI----IRSPVFQK-----QPINILSYKQMSGRAGRMGRDT 495
++LVAT + G+NL R++I I+ + +K +PI Q++GRAGR
Sbjct: 419 KILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRF 478
Query: 496 KGESILICSEAEKKIGFNLMMGDLDPVKS 524
K + + + + ++ +DP+++
Sbjct: 479 KEGEVTTMNHEDLSLLKEILKRPVDPIRA 507
>BC007820-1|AAH07820.1| 299|Homo sapiens FLJ20035 protein protein.
Length = 299
Score = 35.1 bits (77), Expect = 1.9
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 14/162 (8%)
Query: 133 VYSAPTSAGKTLVAEILTIKTVLERQKKVII-ILPFVSIVREKMFYLQNILSSSGIRVEG 191
V APTS+GKT + K + E V++ + P ++V + +QN + + E
Sbjct: 55 VIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEV 114
Query: 192 FMG--SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN-IEDLGAVVVDELHLLGDQNRG 248
G ++ N V I T+ ++ N ++ + V+ DE+H LG +
Sbjct: 115 LCGVFTREYRHDALNCQVLI-TVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA 173
Query: 249 YILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNA 290
I E LL I+ + +SAT+ N E L WL +
Sbjct: 174 EIWEHLLVMIR---------CPFLALSATISNPEHLTEWLQS 206
>AL596223-2|CAH71499.1| 786|Homo sapiens suppressor of var1, 3-like
1 (S. cerevisiae) protein.
Length = 786
Score = 35.1 bits (77), Expect = 1.9
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 445 RVLVATSTLSSGVNLPARKVI----IRSPVFQK-----QPINILSYKQMSGRAGRMGRDT 495
++LVAT + G+NL R++I I+ + +K +PI Q++GRAGR
Sbjct: 419 KILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRF 478
Query: 496 KGESILICSEAEKKIGFNLMMGDLDPVKS 524
K + + + + ++ +DP+++
Sbjct: 479 KEGEVTTMNHEDLSLLKEILKRPVDPIRA 507
>AK001649-1|BAA91809.1| 1174|Homo sapiens protein ( Homo sapiens
cDNA FLJ10787 fis, clone NT2RP4000481, weakly similar to
ATP-DEPENDENT RNA HELICASE DOB1. ).
Length = 1174
Score = 35.1 bits (77), Expect = 1.9
Identities = 41/162 (25%), Positives = 69/162 (42%), Gaps = 14/162 (8%)
Query: 133 VYSAPTSAGKTLVAEILTIKTVLERQKKVII-ILPFVSIVREKMFYLQNILSSSGIRVEG 191
V APTS+GKT + K + E V++ + P ++V + +QN + + E
Sbjct: 782 VIVAPTSSGKTYASYYCMEKVLKESDDGVVVYVAPTKALVNQVAATVQNRFTKNLPSGEV 841
Query: 192 FMG--SQSPAGGMQNVHVAICTIEKANSMINRLLDNGN-IEDLGAVVVDELHLLGDQNRG 248
G ++ N V I T+ ++ N ++ + V+ DE+H LG +
Sbjct: 842 LCGVFTREYRHDALNCQVLI-TVPACFEILLLAPHRQNWVKKIRYVIFDEVHCLGGEIGA 900
Query: 249 YILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNA 290
I E LL I+ + +SAT+ N E L WL +
Sbjct: 901 EIWEHLLVMIR---------CPFLALSATISNPEHLTEWLQS 933
>AF042169-1|AAB97370.1| 786|Homo sapiens putative ATP-dependent
mitochondrial RNA helicase protein.
Length = 786
Score = 35.1 bits (77), Expect = 1.9
Identities = 22/89 (24%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 445 RVLVATSTLSSGVNLPARKVI----IRSPVFQK-----QPINILSYKQMSGRAGRMGRDT 495
++LVAT + G+NL R++I I+ + +K +PI Q++GRAGR
Sbjct: 419 KILVATDAIGMGLNLSIRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRAGRFSSRF 478
Query: 496 KGESILICSEAEKKIGFNLMMGDLDPVKS 524
K + + + + ++ +DP+++
Sbjct: 479 KEGEVTTMNHEDLSLLKEILKRPVDPIRA 507
>BC074781-1|AAH74781.1| 402|Homo sapiens FLJ20035 protein protein.
Length = 402
Score = 33.9 bits (74), Expect = 4.4
Identities = 13/23 (56%), Positives = 19/23 (82%)
Query: 476 INILSYKQMSGRAGRMGRDTKGE 498
++ L+Y+QMSGRAGR G+D G+
Sbjct: 4 LDALNYRQMSGRAGRRGQDLMGD 26
>AK223184-1|BAD96904.1| 409|Homo sapiens Hypothetical protein
FLJ20035 variant protein.
Length = 409
Score = 33.9 bits (74), Expect = 4.4
Identities = 13/23 (56%), Positives = 19/23 (82%)
Query: 476 INILSYKQMSGRAGRMGRDTKGE 498
++ L+Y+QMSGRAGR G+D G+
Sbjct: 11 LDALNYRQMSGRAGRRGQDLMGD 33
>AK055595-1|BAB70966.1| 729|Homo sapiens protein ( Homo sapiens
cDNA FLJ31033 fis, clone HSYRA1000168, weakly similar to
HYPOTHETICAL HELICASE C28H8.3 IN CHROMOSOME III. ).
Length = 729
Score = 33.9 bits (74), Expect = 4.4
Identities = 46/186 (24%), Positives = 75/186 (40%), Gaps = 13/186 (6%)
Query: 133 VYSAPTSAGKTLVAEILTIKTVLERQKKVII-ILPFVSIVREKMFYLQNILSSSGIRVEG 191
V APTS+GKT + K + E V++ + P S+V + ++N + +
Sbjct: 325 VIVAPTSSGKTYASYYCMEKVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRT 384
Query: 192 FMGS--QSPAGGMQNVHVAICTIEKANSMINRLLDNGNIEDLGAVVVDELHLLGDQNRGY 249
G+ + + N V I E ++ +E + V+ DE+H LG +
Sbjct: 385 LCGAFTRDYRHNVLNCQVLITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAK 444
Query: 250 ILELLLTKIKYVTSKSDLLIQVIGMSATLPNLETLATWLNAELFITTFRPIPLEEYCLVE 309
ELLL I+ + +SAT+ N L WL + +EE C+ E
Sbjct: 445 FWELLLVIIR---------CPFLVLSATINNPNLLTKWLQSVKQYWKQADKIMEEKCISE 495
Query: 310 NKYYDK 315
K DK
Sbjct: 496 -KQADK 500
>AY684169-1|AAT74627.1| 3052|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3052
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1446 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1503
>AL512325-2|CAI20998.1| 3130|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
>AL512325-1|CAI20997.1| 3052|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3052
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1446 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1503
>AL136310-1|CAI20509.1| 3130|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
>AL080317-3|CAI19192.1| 3130|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
>AL080317-2|CAI19191.1| 3052|Homo sapiens REV3-like, catalytic subunit
of DNA polymerase zeta (yeast) protein.
Length = 3052
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1446 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1503
>AF179429-1|AAG09403.1| 3052|Homo sapiens DNA polymerase zeta
catalytic subunit variant 2 protein.
Length = 3052
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1446 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1503
>AF179428-1|AAG09402.1| 3052|Homo sapiens DNA polymerase zeta
catalytic subunit variant 1 protein.
Length = 3052
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1446 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1503
>AF157476-1|AAD40184.1| 3130|Homo sapiens DNA polymerase zeta
catalytic subunit protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
>AF155803-1|AAK56799.1| 824|Homo sapiens DEAD-box corepressor DP103
protein.
Length = 824
Score = 33.5 bits (73), Expect = 5.9
Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 9/72 (12%)
Query: 445 RVLVATSTLSSGVNLPARKVIIRSPVFQKQPINILSYKQMSGRAGRMGRDTKGESILICS 504
RVL++T S G++ +++ V P++ +Y GRAGR+G T G ++ C
Sbjct: 361 RVLISTDLTSRGIDAEKVNLVVNLDV----PLDWETYMHRIGRAGRLG--TLGLTVTYCC 414
Query: 505 EAEKKIGFNLMM 516
E++ N+MM
Sbjct: 415 RGEEE---NMMM 423
>AF071798-1|AAC24009.1| 3130|Homo sapiens DNA polymerase zeta
catalytic subunit protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
>AF058701-1|AAC24357.1| 3130|Homo sapiens DNA polymerase zeta
catalytic subunit protein.
Length = 3130
Score = 33.5 bits (73), Expect = 5.9
Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Query: 32 QSSLVVVKEYLEKSENKQKHVNRRFVNTASNNSLLNKTAEGKLTASKEVRNTQKIQSKK 90
QS L V+KE L+K + K ++ N + SN NK G L +K + T+ + S +
Sbjct: 1524 QSGLAVLKELLQKRQQKAQNANTT-QDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPR 1581
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.133 0.380
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 192,122,507
Number of Sequences: 224733
Number of extensions: 7544394
Number of successful extensions: 19743
Number of sequences better than 10.0: 169
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 19233
Number of HSP's gapped (non-prelim): 337
length of query: 1486
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1387
effective length of database: 50,986,271
effective search space: 70717957877
effective search space used: 70717957877
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)
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