Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002413-TA|BGIBMGA002413-PA|IPR003961|Fibronectin, type
III, IPR007110|Immunoglobulin-like, IPR003599|Immunoglobulin subtype,
IPR003598|Immunoglobulin subtype 2, IPR008957|Fibronectin, type
III-like fold, IPR013098|Immunoglobulin I-set
(674 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 370 e-101
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 368 e-101
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 368 e-101
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 365 e-100
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 365 e-100
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 365 e-100
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 365 e-100
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 355 2e-97
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 350 1e-95
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 350 1e-95
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 348 4e-95
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 348 4e-95
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 347 1e-94
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 337 6e-92
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 337 6e-92
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 337 6e-92
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 273 1e-72
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 255 3e-67
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 255 3e-67
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 255 3e-67
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 253 2e-66
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 248 4e-65
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 248 4e-65
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 248 4e-65
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 248 4e-65
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 246 3e-64
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 246 3e-64
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 243 1e-63
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 243 2e-63
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 243 2e-63
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 242 2e-63
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 241 4e-63
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 241 6e-63
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 241 6e-63
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 241 6e-63
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 241 6e-63
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 241 6e-63
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 241 6e-63
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 237 1e-61
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 234 6e-61
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 234 6e-61
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 232 3e-60
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 232 3e-60
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 224 9e-58
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 209 3e-53
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 209 3e-53
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 209 3e-53
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 200 2e-50
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 174 7e-43
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 174 7e-43
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 174 7e-43
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 174 7e-43
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 174 7e-43
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 160 1e-38
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 160 1e-38
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 160 1e-38
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 159 3e-38
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 159 3e-38
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 159 3e-38
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 158 7e-38
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 158 7e-38
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 149 4e-35
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 146 2e-34
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 145 5e-34
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 144 1e-33
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 143 2e-33
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 135 5e-31
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 135 5e-31
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 135 5e-31
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 132 5e-30
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 131 7e-30
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 130 2e-29
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 128 8e-29
BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein. 127 1e-28
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 126 3e-28
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 126 3e-28
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 126 3e-28
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 126 3e-28
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 126 3e-28
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 126 3e-28
AF464063-1|AAN86141.1| 282|Homo sapiens contactin 4a protein. 125 4e-28
AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein. 124 8e-28
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 123 2e-27
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 118 9e-26
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 118 9e-26
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 118 9e-26
AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine phosph... 118 9e-26
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 117 1e-25
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 117 2e-25
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 117 2e-25
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 117 2e-25
AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein pr... 116 2e-25
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 115 6e-25
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 114 1e-24
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 113 1e-24
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 113 2e-24
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 111 6e-24
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 111 8e-24
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 111 8e-24
X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphat... 111 1e-23
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 111 1e-23
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 111 1e-23
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 110 1e-23
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 107 1e-22
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 106 2e-22
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 106 2e-22
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 106 3e-22
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 105 4e-22
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 105 4e-22
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 101 8e-21
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 101 8e-21
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 101 1e-20
AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]... 100 2e-20
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 99 3e-20
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 99 3e-20
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 100 3e-20
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 95 7e-19
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 95 7e-19
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 95 1e-18
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 94 2e-18
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 94 2e-18
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 93 3e-18
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 93 3e-18
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 93 4e-18
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 92 7e-18
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 92 7e-18
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 91 9e-18
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 91 9e-18
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 91 9e-18
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 91 1e-17
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 90 2e-17
AK074077-1|BAB84903.1| 572|Homo sapiens FLJ00148 protein protein. 85 6e-16
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 83 2e-15
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 83 2e-15
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 83 4e-15
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 83 4e-15
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 83 4e-15
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 83 4e-15
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 83 4e-15
AK001694-1|BAA91841.1| 574|Homo sapiens protein ( Homo sapiens ... 81 9e-15
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 81 9e-15
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 81 2e-14
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 80 2e-14
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 80 2e-14
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 80 2e-14
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 80 2e-14
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 80 2e-14
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 80 2e-14
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 80 3e-14
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 80 3e-14
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 80 3e-14
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 80 3e-14
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 79 4e-14
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 79 7e-14
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 79 7e-14
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 79 7e-14
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 77 2e-13
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 77 2e-13
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 77 2e-13
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 77 2e-13
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 77 3e-13
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 77 3e-13
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 76 4e-13
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 76 4e-13
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 76 4e-13
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 76 5e-13
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 76 5e-13
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 76 5e-13
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 75 8e-13
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 75 8e-13
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 75 8e-13
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 75 8e-13
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 75 8e-13
AJ001054-1|CAA04504.1| 148|Homo sapiens NrCAM protein protein. 74 1e-12
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 74 2e-12
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 73 3e-12
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 73 3e-12
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 73 3e-12
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 73 3e-12
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 73 3e-12
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 73 3e-12
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 73 3e-12
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 73 3e-12
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 71 1e-11
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 71 1e-11
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 71 1e-11
X53051-1|CAA37218.1| 739|Homo sapiens precursor peptide protein. 71 2e-11
M73255-1|AAA61270.1| 739|Homo sapiens vascular cell adhesion mo... 71 2e-11
M60335-1|AAA61269.1| 739|Homo sapiens vascular cell adhesion mo... 71 2e-11
BC085003-1|AAH85003.1| 739|Homo sapiens vascular cell adhesion ... 71 2e-11
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 71 2e-11
BC068490-1|AAH68490.2| 739|Homo sapiens vascular cell adhesion ... 71 2e-11
BC017276-1|AAH17276.3| 739|Homo sapiens vascular cell adhesion ... 71 2e-11
AF536818-1|AAM96190.1| 739|Homo sapiens vascular cell adhesion ... 71 2e-11
BC111748-1|AAI11749.1| 1007|Homo sapiens roundabout homolog 4, m... 70 3e-11
BC111562-1|AAI11563.1| 1007|Homo sapiens roundabout homolog 4, m... 70 3e-11
BC039602-1|AAH39602.1| 1007|Homo sapiens roundabout homolog 4, m... 70 3e-11
AY358083-1|AAQ88450.1| 1004|Homo sapiens magic roundabout protein. 70 3e-11
AK027852-1|BAB55411.1| 792|Homo sapiens protein ( Homo sapiens ... 70 3e-11
AF361473-1|AAL31867.1| 1007|Homo sapiens magic roundabout protein. 70 3e-11
BC132812-1|AAI32813.1| 1198|Homo sapiens FNDC3A protein protein. 69 4e-11
BC025843-1|AAH25843.1| 449|Homo sapiens L1CAM protein protein. 69 4e-11
AL137000-1|CAI39726.2| 1142|Homo sapiens fibronectin type III do... 69 4e-11
AK223266-1|BAD96986.1| 739|Homo sapiens vascular cell adhesion ... 69 4e-11
AJ749707-1|CAG44603.1| 1134|Homo sapiens human gene expressed in... 69 4e-11
AJ749706-1|CAG44602.1| 1198|Homo sapiens human gene expressed in... 69 4e-11
AB023187-1|BAA76814.2| 1151|Homo sapiens KIAA0970 protein protein. 69 4e-11
BC070072-1|AAH70072.1| 853|Homo sapiens FNDC3A protein protein. 69 5e-11
BC060816-1|AAH60816.1| 853|Homo sapiens FNDC3A protein protein. 69 5e-11
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 69 7e-11
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 69 7e-11
AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens ... 69 7e-11
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 69 7e-11
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 69 7e-11
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 68 9e-11
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 68 1e-10
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 68 1e-10
BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein. 68 1e-10
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 68 1e-10
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 68 1e-10
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 68 1e-10
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 67 2e-10
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 67 2e-10
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 66 5e-10
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 66 5e-10
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 66 5e-10
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 66 5e-10
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 66 5e-10
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 66 5e-10
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 66 5e-10
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 66 5e-10
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 66 5e-10
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 65 7e-10
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 65 9e-10
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 65 9e-10
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 65 9e-10
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 65 9e-10
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 65 9e-10
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 65 9e-10
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 65 9e-10
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 64 1e-09
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 63 3e-09
BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein pr... 63 3e-09
BC039297-1|AAH39297.1| 1204|Homo sapiens fibronectin type III do... 63 3e-09
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 63 3e-09
AB098597-1|BAC53727.1| 1204|Homo sapiens FAD104 protein. 63 3e-09
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 62 5e-09
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 62 5e-09
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 62 5e-09
EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3 p... 62 6e-09
BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein. 62 6e-09
AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein. 62 6e-09
AL391822-9|CAI14665.1| 297|Homo sapiens neurofascin homolog (ch... 62 6e-09
AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein. 62 6e-09
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 62 8e-09
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 62 8e-09
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 62 8e-09
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 61 1e-08
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 61 1e-08
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 61 1e-08
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 61 1e-08
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 61 1e-08
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 61 1e-08
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 61 1e-08
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 61 1e-08
AY358146-1|AAQ88513.1| 847|Homo sapiens YVTM2421 protein. 61 1e-08
AK223599-1|BAD97319.1| 1204|Homo sapiens factor for adipocyte di... 61 1e-08
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 61 1e-08
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 60 2e-08
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 60 2e-08
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 60 2e-08
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 60 2e-08
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 60 2e-08
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 60 3e-08
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 60 3e-08
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 60 3e-08
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 60 3e-08
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 60 3e-08
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 60 3e-08
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 60 3e-08
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 59 4e-08
AK074556-1|BAC11057.1| 789|Homo sapiens protein ( Homo sapiens ... 59 6e-08
M29273-1|AAA59545.1| 626|Homo sapiens MAG protein. 58 8e-08
BC093045-1|AAH93045.1| 582|Homo sapiens myelin associated glyco... 58 8e-08
BC053347-1|AAH53347.1| 626|Homo sapiens myelin associated glyco... 58 8e-08
BC033635-1|AAH33635.1| 753|Homo sapiens FNDC3B protein protein. 58 8e-08
AK223562-1|BAD97282.1| 626|Homo sapiens myelin associated glyco... 58 8e-08
AK222649-1|BAD96369.1| 626|Homo sapiens myelin associated glyco... 58 8e-08
AC002132-1|AAB58805.1| 626|Homo sapiens MAG protein. 58 8e-08
AB209170-1|BAD92407.1| 661|Homo sapiens myelin associated glyco... 58 8e-08
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 58 1e-07
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 58 1e-07
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 58 1e-07
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 58 1e-07
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 58 1e-07
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 58 1e-07
AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein pr... 58 1e-07
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 58 1e-07
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 58 1e-07
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 58 1e-07
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 58 1e-07
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 58 1e-07
AB209396-1|BAD92633.1| 675|Homo sapiens surface glycoprotein, I... 58 1e-07
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 58 1e-07
AL157482-1|CAB75672.1| 477|Homo sapiens hypothetical protein pr... 58 1e-07
AK075220-1|BAC11480.1| 760|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AK027052-1|BAB15639.1| 495|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AF543840-1|AAN65261.1| 495|Homo sapiens HCV NS5A-binding protei... 58 1e-07
AK074163-1|BAB84989.1| 702|Homo sapiens FLJ00236 protein protein. 57 2e-07
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 57 2e-07
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 57 2e-07
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 57 2e-07
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 56 3e-07
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 56 3e-07
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 56 3e-07
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 56 3e-07
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 56 3e-07
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 56 4e-07
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 56 4e-07
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 56 4e-07
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,... 55 7e-07
BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5 prot... 55 7e-07
AL513328-3|CAI17351.1| 116|Homo sapiens muscle, skeletal, recep... 55 7e-07
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 55 7e-07
AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein. 55 7e-07
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 55 9e-07
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 55 9e-07
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 55 9e-07
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 55 9e-07
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 55 9e-07
M30257-1|AAA51917.1| 647|Homo sapiens VCAM1 protein. 55 9e-07
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 55 9e-07
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 55 9e-07
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 55 9e-07
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 55 9e-07
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 55 9e-07
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 55 9e-07
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 55 9e-07
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 55 9e-07
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 55 9e-07
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 55 9e-07
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 55 9e-07
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 55 9e-07
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 55 9e-07
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 55 9e-07
X75958-1|CAA53571.1| 477|Homo sapiens protein-tyrosine kinase p... 54 1e-06
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 54 1e-06
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 54 1e-06
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 54 1e-06
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 54 1e-06
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 54 1e-06
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 54 1e-06
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 54 1e-06
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 54 1e-06
S76474-1|AAB33110.1| 477|Homo sapiens trkB protein. 54 1e-06
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 54 1e-06
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 54 1e-06
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 54 1e-06
M37397-1|AAA60960.1| 426|Homo sapiens CEA protein. 54 1e-06
M34715-1|AAA36511.1| 426|Homo sapiens pregnancy-specific beta-1... 54 1e-06
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 54 1e-06
M33664-1|AAA36515.1| 419|Homo sapiens protein ( Human pregnancy... 54 1e-06
M33663-1|AAA36517.1| 426|Homo sapiens protein ( Human pregnancy... 54 1e-06
M25385-1|AAA36513.1| 419|Homo sapiens protein ( Human pregnancy... 54 1e-06
M21822-1|AAA52601.1| 419|Homo sapiens PSG1 protein. 54 1e-06
M20881-1|AAA52603.1| 419|Homo sapiens PSG1 protein. 54 1e-06
M20879-1|AAA52602.1| 428|Homo sapiens PSG1 protein. 54 1e-06
M17908-1|AAA52590.1| 417|Homo sapiens PSG1 protein. 54 1e-06
J04539-1|AAA60204.1| 426|Homo sapiens NCA protein. 54 1e-06
CR450329-1|CAG29325.1| 426|Homo sapiens PSG1 protein. 54 1e-06
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 54 1e-06
BC031835-1|AAH31835.1| 477|Homo sapiens neurotrophic tyrosine k... 54 1e-06
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 54 1e-06
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 54 1e-06
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL596132-2|CAH72313.1| 537|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL596132-1|CAH72314.1| 553|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL390777-5|CAH72197.1| 477|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL390777-2|CAH72193.1| 553|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AL390777-1|CAH72194.1| 537|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AF508964-1|AAM77876.1| 477|Homo sapiens protein tyrosine kinase... 54 1e-06
AF410901-1|AAL67967.1| 553|Homo sapiens neurotrophin receptor t... 54 1e-06
AF410900-1|AAL67966.1| 537|Homo sapiens neurotrophin receptor t... 54 1e-06
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 54 1e-06
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 54 1e-06
AC004654-2|AAC15514.1| 426|Homo sapiens F19434_2 protein. 54 1e-06
AB209118-1|BAD92355.1| 781|Homo sapiens BDNF/NT-3 growth factor... 54 1e-06
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 54 1e-06
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 54 2e-06
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 370 bits (910), Expect = e-101
Identities = 217/649 (33%), Positives = 337/649 (51%), Gaps = 26/649 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ +S+A+L V+++ P F + L+ T GG V ++CKP+A+PKP +T
Sbjct: 53 MYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT 112
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK ++ + I+E+GNL I +++ D G YTC+A N +GT S G L+V + P
Sbjct: 113 WKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV-KDPTR 171
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID-GGE 179
+ P + V + L C D LD + W+ NG I D +R+ D G+
Sbjct: 172 VMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGDSAGD 231
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L I N+ L G Y C+V++++ R+S+ L + GPPGPP V I I ++ L W
Sbjct: 232 LMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPG 291
Query: 240 NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRI 299
N PIT Y++ RT ++ W +S +P +++ G+ L PW YEFR
Sbjct: 292 PDNHSPITMYVIQARTPFSVGWQAVS-TVPELID-----GKTFTATVVGLNPWVEYEFRT 345
Query: 300 QAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIH 359
A N++G G+PS PS + T P PANVSGGGG +L ITW +P LQNG G
Sbjct: 346 VAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFG 405
Query: 360 YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
Y + +R G + ++L + YV S + ++P++VKV FN+ G GP S
Sbjct: 406 YVVAFRPYGKMIWMLTVLAS--ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTT 463
Query: 420 TIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQENKEE 478
+YSAE+ P P + ARS ++T + V W +P+ E+ RG++ G+ +KYW+ E+KEE
Sbjct: 464 VVYSAEEEPTKPPASIFARSLSATDIEVFWASPL----EKNRGRIQGYEVKYWRHEDKEE 519
Query: 479 ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASV 538
+ + I L+ Y++ V A+NSAG GP S T + P +PP ++
Sbjct: 520 NARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI 579
Query: 539 NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISN 598
+W + + + W V+ + E + GYKV L+ ++ ST+ IE + +
Sbjct: 580 -IWNSSDSKIILNWDQVKALDNESEVKGYKV-LYRWNRQSSTS-----VIETNKTSVELS 632
Query: 599 IIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIGDYHSEAYGYYARGSTSN 647
+ + Y + + +S+GGDG S +I S AY + STSN
Sbjct: 633 LPFDEDYIIEIKPFSDGGDGSSSEQIRIPKI----SNAYARGSGASTSN 677
Score = 79.8 bits (188), Expect = 3e-14
Identities = 57/175 (32%), Positives = 79/175 (45%), Gaps = 12/175 (6%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQY 103
NV +CK PKPT+ W K+ + R E G L I ++ D G+Y C+A+N++
Sbjct: 4 NVFWECKANGRPKPTYKWLKNGEPL-LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKH 62
Query: 104 GTDESRGRLIVLR-APRFLEKLPPRIT-AQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G S L V+ P F L R+T +V V + C P Y W
Sbjct: 63 GVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASP--KPVYTWK------ 114
Query: 162 KDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
K L N+RI I + G L I NV+ SD G Y C+ + G SS L ++ P
Sbjct: 115 KGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDP 169
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 368 bits (906), Expect = e-101
Identities = 216/650 (33%), Positives = 337/650 (51%), Gaps = 27/650 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ +S+A+L V+++ P F + L+ T GG V ++CKP+A+PKP +T
Sbjct: 381 MYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT 440
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK ++ + I+E+GNL I +++ D G YTC+A N +GT S G L+V + P
Sbjct: 441 WKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV-KDPTR 499
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI--KIDGG 178
+ P + V + L C D LD + W+ NG I D +R+ + G
Sbjct: 500 VMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAG 559
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C+V++++ R+S+ L + GPPGPP V I I ++ L W
Sbjct: 560 DLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRP 619
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PIT Y++ RT ++ W +S +P +++ G+ L PW YEFR
Sbjct: 620 GPDNHSPITMYVIQARTPFSVGWQAVS-TVPELID-----GKTFTATVVGLNPWVEYEFR 673
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
A N++G G+PS PS + T P PANVSGGGG +L ITW +P LQNG G
Sbjct: 674 TVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGF 733
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R G + ++L + YV S + ++P++VKV FN+ G GP S
Sbjct: 734 GYVVAFRPYGKMIWMLTVLAS--ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPT 791
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P P + ARS ++T + V W +P+ E+ RG++ G+ +KYW+ E+KE
Sbjct: 792 TVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL----EKNRGRIQGYEVKYWRHEDKE 847
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
E + + I L+ Y++ V A+NSAG GP S T + P +PP +
Sbjct: 848 ENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGN 907
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
+ +W + + + W V+ + E + GYKV L+ ++ ST+ IE +
Sbjct: 908 I-IWNSSDSKIILNWDQVKALDNESEVKGYKV-LYRWNRQSSTS-----VIETNKTSVEL 960
Query: 598 NIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIGDYHSEAYGYYARGSTSN 647
++ + Y + + +S+GGDG S +I S AY + STSN
Sbjct: 961 SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKI----SNAYARGSGASTSN 1006
Score = 84.6 bits (200), Expect = 1e-15
Identities = 65/218 (29%), Positives = 99/218 (45%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + + QL + +P++ + ++ E NV +CK PKPT+
Sbjct: 292 LYECVAENSRGKNVARGQLTFYA-QPNWIQKINDIHVAMEE--NVFWECKANGRPKPTYK 348
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + R E G L I ++ D G+Y C+A+N++G S L V+ P
Sbjct: 349 WLKNGEPL-LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPD 407
Query: 120 FLEKLPPRIT-AQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L R+T +V V + C P Y W K L N+RI I +
Sbjct: 408 FSRTLLKRVTLVKVGGEVVIECKPKASP--KPVYTWK------KGRDILKENERITISED 459
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I NV+ SD G Y C+ + G SS L ++ P
Sbjct: 460 GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDP 497
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCV 98
++G V L+C P PT W++ D I +R NG L I ++D G+Y CV
Sbjct: 238 AKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-KSNGILEIPNFQQEDAGLYECV 296
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
A+N G + +RG+L P +++K+ I + VF C A+ P Y W
Sbjct: 297 AENSRGKNVARGQLTFYAQPNWIQKIND-IHVAMEENVFWECKANGRP--KPTYKW---- 349
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+K+ L RI+I+ G L I V+LSD G Y+C+ ++ G I S+ +L +
Sbjct: 350 --LKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 61.7 bits (143), Expect = 8e-09
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGNLIIRQLSR-DDEGVYTC 97
SE V L C+ + PKP WK + + G R+ G+L+I ++ D G Y C
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQC 100
Query: 98 VAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
A N +GT SR +L F + ++ + + L C + +Y W
Sbjct: 101 TATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHS-GELSYAWIF 159
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N + +V++ + G L I V SDVG+Y CVV + +++H ++ GPP
Sbjct: 160 NEYPSYQDNRRFVSQ----ETGNLYIAKVEKSDVGNYTCVVTNT---VTNH---KVLGPP 209
Query: 217 GP 218
P
Sbjct: 210 TP 211
Score = 55.2 bits (127), Expect = 7e-07
Identities = 62/259 (23%), Positives = 98/259 (37%), Gaps = 20/259 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC A N S + +FK + G V L P + + ++ W
Sbjct: 98 YQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAW 157
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG--RLIVLRAP 118
+ +RF++ E GNL I ++ + D G YTCV N + G ++LR
Sbjct: 158 IFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRND 217
Query: 119 RFLEKLPPRITAQV--------NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
+ + P+I Q + V L C A +P+ +W R D +
Sbjct: 218 GVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPV--PTIIW-----RRADGKPIARK 270
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
R G L I N D G YECV +++ G+ + QL P + + +
Sbjct: 271 ARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAME 330
Query: 231 SVTLEWTDSNSNGRPITGY 249
+ W + +NGRP Y
Sbjct: 331 E-NVFW-ECKANGRPKPTY 347
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 368 bits (906), Expect = e-101
Identities = 216/650 (33%), Positives = 337/650 (51%), Gaps = 27/650 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ +S+A+L V+++ P F + L+ T GG V ++CKP+A+PKP +T
Sbjct: 381 MYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYT 440
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK ++ + I+E+GNL I +++ D G YTC+A N +GT S G L+V + P
Sbjct: 441 WKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVV-KDPTR 499
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI--KIDGG 178
+ P + V + L C D LD + W+ NG I D +R+ + G
Sbjct: 500 VMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAG 559
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C+V++++ R+S+ L + GPPGPP V I I ++ L W
Sbjct: 560 DLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRP 619
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PIT Y++ RT ++ W +S +P +++ G+ L PW YEFR
Sbjct: 620 GPDNHSPITMYVIQARTPFSVGWQAVS-TVPELID-----GKTFTATVVGLNPWVEYEFR 673
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
A N++G G+PS PS + T P PANVSGGGG +L ITW +P LQNG G
Sbjct: 674 TVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGF 733
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R G + ++L + YV S + ++P++VKV FN+ G GP S
Sbjct: 734 GYVVAFRPYGKMIWMLTVLAS--ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPT 791
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P P + ARS ++T + V W +P+ E+ RG++ G+ +KYW+ E+KE
Sbjct: 792 TVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL----EKNRGRIQGYEVKYWRHEDKE 847
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
E + + I L+ Y++ V A+NSAG GP S T + P +PP +
Sbjct: 848 ENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGN 907
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
+ +W + + + W V+ + E + GYKV L+ ++ ST+ IE +
Sbjct: 908 I-IWNSSDSKIILNWDQVKALDNESEVKGYKV-LYRWNRQSSTS-----VIETNKTSVEL 960
Query: 598 NIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIGDYHSEAYGYYARGSTSN 647
++ + Y + + +S+GGDG S +I S AY + STSN
Sbjct: 961 SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKI----SNAYARGSGASTSN 1006
Score = 84.6 bits (200), Expect = 1e-15
Identities = 65/218 (29%), Positives = 99/218 (45%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + + QL + +P++ + ++ E NV +CK PKPT+
Sbjct: 292 LYECVAENSRGKNVARGQLTFYA-QPNWIQKINDIHVAMEE--NVFWECKANGRPKPTYK 348
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + R E G L I ++ D G+Y C+A+N++G S L V+ P
Sbjct: 349 WLKNGEPL-LTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPD 407
Query: 120 FLEKLPPRIT-AQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L R+T +V V + C P Y W K L N+RI I +
Sbjct: 408 FSRTLLKRVTLVKVGGEVVIECKPKASP--KPVYTWK------KGRDILKENERITISED 459
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I NV+ SD G Y C+ + G SS L ++ P
Sbjct: 460 GNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDP 497
Score = 84.2 bits (199), Expect = 1e-15
Identities = 55/174 (31%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCV 98
++G V L+C P PT W++ D I +R NG L I ++D G+Y CV
Sbjct: 238 AKGATVKLECFALGNPVPTIIWRRADGKPIARKARRH-KSNGILEIPNFQQEDAGLYECV 296
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
A+N G + +RG+L P +++K+ I + VF C A+ P Y W
Sbjct: 297 AENSRGKNVARGQLTFYAQPNWIQKIND-IHVAMEENVFWECKANGRP--KPTYKW---- 349
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+K+ L RI+I+ G L I V+LSD G Y+C+ ++ G I S+ +L +
Sbjct: 350 --LKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSV 401
Score = 61.7 bits (143), Expect = 8e-09
Identities = 50/182 (27%), Positives = 80/182 (43%), Gaps = 14/182 (7%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGNLIIRQLSR-DDEGVYTC 97
SE V L C+ + PKP WK + + G R+ G+L+I ++ D G Y C
Sbjct: 41 SEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQC 100
Query: 98 VAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
A N +GT SR +L F + ++ + + L C + +Y W
Sbjct: 101 TATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHS-GELSYAWIF 159
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N + +V++ + G L I V SDVG+Y CVV + +++H ++ GPP
Sbjct: 160 NEYPSYQDNRRFVSQ----ETGNLYIAKVEKSDVGNYTCVVTNT---VTNH---KVLGPP 209
Query: 217 GP 218
P
Sbjct: 210 TP 211
Score = 55.2 bits (127), Expect = 7e-07
Identities = 62/259 (23%), Positives = 98/259 (37%), Gaps = 20/259 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC A N S + +FK + G V L P + + ++ W
Sbjct: 98 YQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAW 157
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG--RLIVLRAP 118
+ +RF++ E GNL I ++ + D G YTCV N + G ++LR
Sbjct: 158 IFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRND 217
Query: 119 RFLEKLPPRITAQV--------NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
+ + P+I Q + V L C A +P+ +W R D +
Sbjct: 218 GVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPV--PTIIW-----RRADGKPIARK 270
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
R G L I N D G YECV +++ G+ + QL P + + +
Sbjct: 271 ARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAME 330
Query: 231 SVTLEWTDSNSNGRPITGY 249
+ W + +NGRP Y
Sbjct: 331 E-NVFW-ECKANGRPKPTY 347
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 365 bits (898), Expect = e-100
Identities = 200/572 (34%), Positives = 293/572 (51%), Gaps = 17/572 (2%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ Y+SA+L V +L P F+ +P+ + GG + + C+P AAPK
Sbjct: 392 MYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVL 451
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K ++ + +T +G LIIR +SR DEG YTC A+N G S G L V A +
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK- 510
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI--KDSSDLYVNKRIKIDGG 178
+ P + + L C+A DP +D + W + I Y +K G
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIG 570
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+LTI N L G Y C+ ++ + S + + GPPGPPGGV + I +++ L W+
Sbjct: 571 DLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSR 630
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI Y L RT W + N N+ G L PW YEFR
Sbjct: 631 GFDNHSPIAKYTLQARTPPAGKWKQVRTNPANI------EGNAETAQVLGLTPWMDYEFR 684
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A NILG G+PS PS + T P AP+ +SGGGG G+L + WTP+ QNG G
Sbjct: 685 VIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGF 744
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS-STYFYTPYDVKVQAFNDIGPGPESE 417
Y + +RR GS +Q+ + G Y V+ + S YTP++VK++++N G GPES
Sbjct: 745 GYLLSFRRQGS-THWQTARVP--GADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESL 801
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P+VAP V A+ +S+ +NVTW P+ Q + G L+G+ ++YWK +KE
Sbjct: 802 TALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD---MNGILLGYEIRYWKAGDKE 858
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
+ A + GL P+T Y+V V A+N AG GP S T + P++PP +
Sbjct: 859 AAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGN 918
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
++ W ++L + W V P E + GYK+
Sbjct: 919 IS-WTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 79.0 bits (186), Expect = 5e-14
Identities = 59/188 (31%), Positives = 85/188 (45%), Gaps = 13/188 (6%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIR 85
PS K ETY G VTL+C P P W+K V G+ ++ T L I
Sbjct: 239 PSIKAR-FPAETYALVGQQVTLECFAFGNPVPRIKWRK---VDGSLSPQWTTAEPTLQIP 294
Query: 86 QLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD 145
+S +DEG Y C A+N G D +GR+IV P +L K+ A + S + C A
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWL-KVISDTEADIGSNLRWGCAAAGK 353
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRIS 205
P W NG L R+++ G+L +SL D G Y+CV ++ G I
Sbjct: 354 P--RPTVRWLRNG------EPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIY 405
Query: 206 SHVQLRIE 213
+ +L ++
Sbjct: 406 ASAELAVQ 413
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/224 (27%), Positives = 97/224 (43%), Gaps = 6/224 (2%)
Query: 400 YDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y+ +V A N +G G P I + E P VAP +S L V W P+ SRE
Sbjct: 681 YEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM--SREY 738
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALI-VGLQPDTYYYVKVMAFNSAGEGP 517
G G+ L + +Q + + + + ++P T + VK+ ++N G+GP
Sbjct: 739 QNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGP 798
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
ES L + + P+ P V + + V W VQ + LLGY++R W+ D
Sbjct: 799 ESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQ-DMNGILLGYEIRYWKAG-D 856
Query: 578 MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
A D + A +S + P Y++ V AY+ G G S
Sbjct: 857 KEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPAS 900
Score = 58.4 bits (135), Expect = 8e-08
Identities = 55/193 (28%), Positives = 82/193 (42%), Gaps = 9/193 (4%)
Query: 12 ASYSSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA 70
+++SSA + P F+ PL L S V L C+ A+P T+ WK + +
Sbjct: 23 SAWSSALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKL 82
Query: 71 G-GKRFITENGNLIIRQLSR-DDEGVYTCVAKNQYGTDESRGRLIVLR-APRFLEKLPPR 127
G R GNL+I ++ D GVY C+A N GT SR ++ F ++
Sbjct: 83 EPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDP 142
Query: 128 ITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVS 186
+ A V L CN P L +L N I +V++ G L I +
Sbjct: 143 VKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTT----GNLYIARTN 198
Query: 187 LSDVGDYECVVKS 199
SD+G+Y C+ S
Sbjct: 199 ASDLGNYSCLATS 211
Score = 36.3 bits (80), Expect = 0.35
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 7/72 (9%)
Query: 136 VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYN-VSLSDVGDYE 194
V L C A P Y W NG +K L R ++ GG L I N D G Y+
Sbjct: 57 VLLACRARASP--PATYRWKMNGTEMK----LEPGSRHQLVGGNLVIMNPTKAQDAGVYQ 110
Query: 195 CVVKSAIGRISS 206
C+ + +G + S
Sbjct: 111 CLASNPVGTVVS 122
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 365 bits (898), Expect = e-100
Identities = 200/572 (34%), Positives = 293/572 (51%), Gaps = 17/572 (2%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ Y+SA+L V +L P F+ +P+ + GG + + C+P AAPK
Sbjct: 392 MYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVL 451
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K ++ + +T +G LIIR +SR DEG YTC A+N G S G L V A +
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK- 510
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI--KDSSDLYVNKRIKIDGG 178
+ P + + L C+A DP +D + W + I Y +K G
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIG 570
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+LTI N L G Y C+ ++ + S + + GPPGPPGGV + I +++ L W+
Sbjct: 571 DLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSR 630
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI Y L RT W + N N+ G L PW YEFR
Sbjct: 631 GFDNHSPIAKYTLQARTPPAGKWKQVRTNPANI------EGNAETAQVLGLTPWMDYEFR 684
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A NILG G+PS PS + T P AP+ +SGGGG G+L + WTP+ QNG G
Sbjct: 685 VIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGF 744
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS-STYFYTPYDVKVQAFNDIGPGPESE 417
Y + +RR GS +Q+ + G Y V+ + S YTP++VK++++N G GPES
Sbjct: 745 GYLLSFRRQGS-THWQTARVP--GADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESL 801
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P+VAP V A+ +S+ +NVTW P+ Q + G L+G+ ++YWK +KE
Sbjct: 802 TALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD---MNGILLGYEIRYWKAGDKE 858
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
+ A + GL P+T Y+V V A+N AG GP S T + P++PP +
Sbjct: 859 AAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGN 918
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
++ W ++L + W V P E + GYK+
Sbjct: 919 IS-WTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 79.0 bits (186), Expect = 5e-14
Identities = 59/188 (31%), Positives = 85/188 (45%), Gaps = 13/188 (6%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIR 85
PS K ETY G VTL+C P P W+K V G+ ++ T L I
Sbjct: 239 PSIKAR-FPAETYALVGQQVTLECFAFGNPVPRIKWRK---VDGSLSPQWTTAEPTLQIP 294
Query: 86 QLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD 145
+S +DEG Y C A+N G D +GR+IV P +L K+ A + S + C A
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWL-KVISDTEADIGSNLRWGCAAAGK 353
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRIS 205
P W NG L R+++ G+L +SL D G Y+CV ++ G I
Sbjct: 354 P--RPTVRWLRNG------EPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIY 405
Query: 206 SHVQLRIE 213
+ +L ++
Sbjct: 406 ASAELAVQ 413
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/224 (27%), Positives = 97/224 (43%), Gaps = 6/224 (2%)
Query: 400 YDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y+ +V A N +G G P I + E P VAP +S L V W P+ SRE
Sbjct: 681 YEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM--SREY 738
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALI-VGLQPDTYYYVKVMAFNSAGEGP 517
G G+ L + +Q + + + + ++P T + VK+ ++N G+GP
Sbjct: 739 QNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGP 798
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
ES L + + P+ P V + + V W VQ + LLGY++R W+ D
Sbjct: 799 ESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQ-DMNGILLGYEIRYWKAG-D 856
Query: 578 MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
A D + A +S + P Y++ V AY+ G G S
Sbjct: 857 KEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPAS 900
Score = 58.4 bits (135), Expect = 8e-08
Identities = 55/193 (28%), Positives = 82/193 (42%), Gaps = 9/193 (4%)
Query: 12 ASYSSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA 70
+++SSA + P F+ PL L S V L C+ A+P T+ WK + +
Sbjct: 23 SAWSSALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKL 82
Query: 71 G-GKRFITENGNLIIRQLSR-DDEGVYTCVAKNQYGTDESRGRLIVLR-APRFLEKLPPR 127
G R GNL+I ++ D GVY C+A N GT SR ++ F ++
Sbjct: 83 EPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDP 142
Query: 128 ITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVS 186
+ A V L CN P L +L N I +V++ G L I +
Sbjct: 143 VKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTT----GNLYIARTN 198
Query: 187 LSDVGDYECVVKS 199
SD+G+Y C+ S
Sbjct: 199 ASDLGNYSCLATS 211
Score = 36.3 bits (80), Expect = 0.35
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 7/72 (9%)
Query: 136 VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYN-VSLSDVGDYE 194
V L C A P Y W NG +K L R ++ GG L I N D G Y+
Sbjct: 57 VLLACRARASP--PATYRWKMNGTEMK----LEPGSRHQLVGGNLVIMNPTKAQDAGVYQ 110
Query: 195 CVVKSAIGRISS 206
C+ + +G + S
Sbjct: 111 CLASNPVGTVVS 122
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 365 bits (898), Expect = e-100
Identities = 200/572 (34%), Positives = 293/572 (51%), Gaps = 17/572 (2%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ Y+SA+L V +L P F+ +P+ + GG + + C+P AAPK
Sbjct: 392 MYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVL 451
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K ++ + +T +G LIIR +SR DEG YTC A+N G S G L V A +
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK- 510
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI--KDSSDLYVNKRIKIDGG 178
+ P + + L C+A DP +D + W + I Y +K G
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIG 570
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+LTI N L G Y C+ ++ + S + + GPPGPPGGV + I +++ L W+
Sbjct: 571 DLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSR 630
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI Y L RT W + N N+ G L PW YEFR
Sbjct: 631 GFDNHSPIAKYTLQARTPPAGKWKQVRTNPANI------EGNAETAQVLGLTPWMDYEFR 684
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A NILG G+PS PS + T P AP+ +SGGGG G+L + WTP+ QNG G
Sbjct: 685 VIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGF 744
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS-STYFYTPYDVKVQAFNDIGPGPESE 417
Y + +RR GS +Q+ + G Y V+ + S YTP++VK++++N G GPES
Sbjct: 745 GYLLSFRRQGS-THWQTARVP--GADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESL 801
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P+VAP V A+ +S+ +NVTW P+ Q + G L+G+ ++YWK +KE
Sbjct: 802 TALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD---MNGILLGYEIRYWKAGDKE 858
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
+ A + GL P+T Y+V V A+N AG GP S T + P++PP +
Sbjct: 859 AAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGN 918
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
++ W ++L + W V P E + GYK+
Sbjct: 919 IS-WTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 79.0 bits (186), Expect = 5e-14
Identities = 59/188 (31%), Positives = 85/188 (45%), Gaps = 13/188 (6%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIR 85
PS K ETY G VTL+C P P W+K V G+ ++ T L I
Sbjct: 239 PSIKAR-FPAETYALVGQQVTLECFAFGNPVPRIKWRK---VDGSLSPQWTTAEPTLQIP 294
Query: 86 QLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD 145
+S +DEG Y C A+N G D +GR+IV P +L K+ A + S + C A
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWL-KVISDTEADIGSNLRWGCAAAGK 353
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRIS 205
P W NG L R+++ G+L +SL D G Y+CV ++ G I
Sbjct: 354 P--RPTVRWLRNG------EPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIY 405
Query: 206 SHVQLRIE 213
+ +L ++
Sbjct: 406 ASAELAVQ 413
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/224 (27%), Positives = 97/224 (43%), Gaps = 6/224 (2%)
Query: 400 YDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y+ +V A N +G G P I + E P VAP +S L V W P+ SRE
Sbjct: 681 YEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM--SREY 738
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALI-VGLQPDTYYYVKVMAFNSAGEGP 517
G G+ L + +Q + + + + ++P T + VK+ ++N G+GP
Sbjct: 739 QNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGP 798
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
ES L + + P+ P V + + V W VQ + LLGY++R W+ D
Sbjct: 799 ESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQ-DMNGILLGYEIRYWKAG-D 856
Query: 578 MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
A D + A +S + P Y++ V AY+ G G S
Sbjct: 857 KEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPAS 900
Score = 58.8 bits (136), Expect = 6e-08
Identities = 55/193 (28%), Positives = 82/193 (42%), Gaps = 9/193 (4%)
Query: 12 ASYSSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA 70
+++SSA + P F+ PL L S V L C+ A+P T+ WK + +
Sbjct: 23 SAWSSALESQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKL 82
Query: 71 G-GKRFITENGNLIIRQLSR-DDEGVYTCVAKNQYGTDESRGRLIVLR-APRFLEKLPPR 127
G R GNL+I ++ D GVY C+A N GT SR ++ F ++
Sbjct: 83 EPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDP 142
Query: 128 ITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVS 186
+ A V L CN P L +L N I +V++ G L I +
Sbjct: 143 VKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTT----GNLYIARTN 198
Query: 187 LSDVGDYECVVKS 199
SD+G+Y C+ S
Sbjct: 199 ASDLGNYSCLATS 211
Score = 36.3 bits (80), Expect = 0.35
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 7/72 (9%)
Query: 136 VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYN-VSLSDVGDYE 194
V L C A P Y W NG +K L R ++ GG L I N D G Y+
Sbjct: 57 VLLACRARASP--PATYRWKMNGTEMK----LEPGSRHQLVGGNLVIMNPTKAQDAGVYQ 110
Query: 195 CVVKSAIGRISS 206
C+ + +G + S
Sbjct: 111 CLASNPVGTVVS 122
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 365 bits (898), Expect = e-100
Identities = 200/572 (34%), Positives = 293/572 (51%), Gaps = 17/572 (2%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ Y+SA+L V +L P F+ +P+ + GG + + C+P AAPK
Sbjct: 392 MYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVL 451
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K ++ + +T +G LIIR +SR DEG YTC A+N G S G L V A +
Sbjct: 452 WSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK- 510
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI--KDSSDLYVNKRIKIDGG 178
+ P + + L C+A DP +D + W + I Y +K G
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIG 570
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+LTI N L G Y C+ ++ + S + + GPPGPPGGV + I +++ L W+
Sbjct: 571 DLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSR 630
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI Y L RT W + N N+ G L PW YEFR
Sbjct: 631 GFDNHSPIAKYTLQARTPPAGKWKQVRTNPANI------EGNAETAQVLGLTPWMDYEFR 684
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A NILG G+PS PS + T P AP+ +SGGGG G+L + WTP+ QNG G
Sbjct: 685 VIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGF 744
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS-STYFYTPYDVKVQAFNDIGPGPESE 417
Y + +RR GS +Q+ + G Y V+ + S YTP++VK++++N G GPES
Sbjct: 745 GYLLSFRRQGS-THWQTARVP--GADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESL 801
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+YSAE+ P+VAP V A+ +S+ +NVTW P+ Q + G L+G+ ++YWK +KE
Sbjct: 802 TALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQD---MNGILLGYEIRYWKAGDKE 858
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
+ A + GL P+T Y+V V A+N AG GP S T + P++PP +
Sbjct: 859 AAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGN 918
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
++ W ++L + W V P E + GYK+
Sbjct: 919 IS-WTFSSSSLSIKWDPVVPFRNESAVTGYKM 949
Score = 79.0 bits (186), Expect = 5e-14
Identities = 59/188 (31%), Positives = 85/188 (45%), Gaps = 13/188 (6%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIR 85
PS K ETY G VTL+C P P W+K V G+ ++ T L I
Sbjct: 239 PSIKAR-FPAETYALVGQQVTLECFAFGNPVPRIKWRK---VDGSLSPQWTTAEPTLQIP 294
Query: 86 QLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD 145
+S +DEG Y C A+N G D +GR+IV P +L K+ A + S + C A
Sbjct: 295 SVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWL-KVISDTEADIGSNLRWGCAAAGK 353
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRIS 205
P W NG L R+++ G+L +SL D G Y+CV ++ G I
Sbjct: 354 P--RPTVRWLRNG------EPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIY 405
Query: 206 SHVQLRIE 213
+ +L ++
Sbjct: 406 ASAELAVQ 413
Score = 78.6 bits (185), Expect = 7e-14
Identities = 62/224 (27%), Positives = 97/224 (43%), Gaps = 6/224 (2%)
Query: 400 YDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y+ +V A N +G G P I + E P VAP +S L V W P+ SRE
Sbjct: 681 YEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM--SREY 738
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALI-VGLQPDTYYYVKVMAFNSAGEGP 517
G G+ L + +Q + + + + ++P T + VK+ ++N G+GP
Sbjct: 739 QNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGP 798
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
ES L + + P+ P V + + V W VQ + LLGY++R W+ D
Sbjct: 799 ESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQQ-DMNGILLGYEIRYWKAG-D 856
Query: 578 MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
A D + A +S + P Y++ V AY+ G G S
Sbjct: 857 KEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPAS 900
Score = 58.4 bits (135), Expect = 8e-08
Identities = 55/193 (28%), Positives = 82/193 (42%), Gaps = 9/193 (4%)
Query: 12 ASYSSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA 70
+++SSA + P F+ PL L S V L C+ A+P T+ WK + +
Sbjct: 23 SAWSSALGSQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKL 82
Query: 71 G-GKRFITENGNLIIRQLSR-DDEGVYTCVAKNQYGTDESRGRLIVLR-APRFLEKLPPR 127
G R GNL+I ++ D GVY C+A N GT SR ++ F ++
Sbjct: 83 EPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDP 142
Query: 128 ITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVS 186
+ A V L CN P L +L N I +V++ G L I +
Sbjct: 143 VKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTT----GNLYIARTN 198
Query: 187 LSDVGDYECVVKS 199
SD+G+Y C+ S
Sbjct: 199 ASDLGNYSCLATS 211
Score = 36.3 bits (80), Expect = 0.35
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 7/72 (9%)
Query: 136 VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYN-VSLSDVGDYE 194
V L C A P Y W NG +K L R ++ GG L I N D G Y+
Sbjct: 57 VLLACRARASP--PATYRWKMNGTEMK----LEPGSRHQLVGGNLVIMNPTKAQDAGVYQ 110
Query: 195 CVVKSAIGRISS 206
C+ + +G + S
Sbjct: 111 CLASNPVGTVVS 122
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 355 bits (874), Expect = 2e-97
Identities = 217/669 (32%), Positives = 329/669 (49%), Gaps = 30/669 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
M+QC A+N+ YSSA+L+V++ P F K+P++ G V+L CKP A+P+ +
Sbjct: 275 MFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSS 334
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK ++ + + + +G L I +++ D G YTC+A+NQ+G L+V P
Sbjct: 335 WKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTE-PTR 393
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDGGE 179
+ P + V V L C DP+LD + W NG D + K G+
Sbjct: 394 ITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGD 453
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L I N+ L G Y C+V++ + +SS L + G PGPP V++ I ++ L W +
Sbjct: 454 LMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEG 513
Query: 240 NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRI 299
N P+ Y + RT ++ W ++ +P V++ G+ L PW YEFR+
Sbjct: 514 KDNHSPVISYSIQARTPFSVGWQTVT-TVPEVID-----GKTHTATVVELNPWVEYEFRV 567
Query: 300 QAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIH 359
A N +G G+PS PS + T P P+ V+GGGG +L ITW P+P LQNG G
Sbjct: 568 VASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFG 627
Query: 360 YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
Y + +R G Q+++ + YV S Y+PY+VKV +N+ G GP S V
Sbjct: 628 YVVAFRPLGVTTWIQTVVTSP--DTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVT 685
Query: 420 TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEE 479
T++SAE+ P VAP VSA S +S+ + V+WN I G L+G+ ++YW KEE
Sbjct: 686 TVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLS--NGHLLGYEVRYWNGGGKEES 743
Query: 480 CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVN 539
A + GL+ + YY V A+NSAG GP S T + P +PP +V
Sbjct: 744 SSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNV- 802
Query: 540 VWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNI 599
VW T + + W V+ E + GYKV S+ N+ V +K A + +
Sbjct: 803 VWNATDTKVLLNWEQVKAMENESEVTGYKV-----FYRTSSQNNVQVLNTNKTSAEL--V 855
Query: 600 IPGK-SYNLRVLAYSNGGDGRMSSPTIAFQIGDYHSEAYGYYARGSTS--NHRHKPVEFL 656
+P K Y + V A ++GGDG S +I ARGSTS ++ H ++
Sbjct: 856 LPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMD-------ARGSTSAISNVHPMSSYM 908
Query: 657 LASIFLVYF 665
+FL+ +
Sbjct: 909 PIVLFLIVY 917
Score = 77.4 bits (182), Expect = 2e-13
Identities = 45/173 (26%), Positives = 86/173 (49%), Gaps = 9/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++G V L+C P P W++ + + + + +G L I ++D G Y C+A
Sbjct: 132 AKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIA 191
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
+N G + +RGRL P +++ + + V ++ C A P +Y W NG
Sbjct: 192 ENSRGKNVARGRLTYYAKPHWVQLIKD-VEIAVEDSLYWECRASGKP--KPSYRWLKNG- 247
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ L + +R +I+ G LTI N+S++D G ++C+ ++ G + S +L++
Sbjct: 248 -----AALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKV 295
Score = 75.4 bits (177), Expect = 6e-13
Identities = 58/218 (26%), Positives = 106/218 (48%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N + + +L + KP + + ++E + ++ +C+ PKP++ W
Sbjct: 187 YECIAENSRGKNVARGRLTYYA-KPHWVQLIKDVEIAVED--SLYWECRASGKPKPSYRW 243
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL-IVLRAPRF 120
K+ + + I ENG L I LS D G++ C+A+N++G S L +V AP F
Sbjct: 244 LKNGAALVLEERTQI-ENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDF 302
Query: 121 LEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI--DG 177
+ + + QV S+V L C P ++ W + +++ ++RI + DG
Sbjct: 303 SKNPMKKLVQVQVGSLVSLDCKPRASPRALSS--WKKGDVSVQE------HERISLLNDG 354
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I NV+ +D G Y C+ ++ G+ + L + P
Sbjct: 355 G-LKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEP 391
Score = 43.6 bits (98), Expect = 0.002
Identities = 54/220 (24%), Positives = 95/220 (43%), Gaps = 17/220 (7%)
Query: 41 EGGNVTLKCKPEA-APKPTFTWKKDNI--VIGAGGKRFIT-ENGNLIIRQLSRDDEGVYT 96
EG V L C P + + ++ W + + +RF++ E G+L I ++ D G YT
Sbjct: 28 EGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYT 87
Query: 97 CVAKNQYGTDESRG--RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
CV + G +VLR+ + + P+I Q + + V L+ L
Sbjct: 88 CVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVK--LECFALG 145
Query: 155 NH-NGLRIKDSSDLYVNKRIKID--GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
N + + S L + +IK+ G L I N D G YEC+ +++ G+ + +L
Sbjct: 146 NPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLT 205
Query: 212 IEGPPGPPGGVQILGIQRSSV--TLEWTDSNSNGRPITGY 249
P VQ++ +V +L W + ++G+P Y
Sbjct: 206 YY---AKPHWVQLIKDVEIAVEDSLYW-ECRASGKPKPSY 241
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 350 bits (860), Expect = 1e-95
Identities = 204/627 (32%), Positives = 329/627 (52%), Gaps = 29/627 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ + Y++A+LRVL+ P F K P++ +++ GG++ + CKP A P+ +
Sbjct: 383 VYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAIS 442
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WK+ + + F+ E+G+L I ++R D G YTC+A NQ+GT ++ G LIV R
Sbjct: 443 WKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIV--KERT 500
Query: 121 LEKLPP-RITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-G 178
+ +PP ++ V + L C DP ++ ++W NG I + +RI + G
Sbjct: 501 VITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVG 560
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ + +S+ + + GPPGPP VQ+ I ++ L W
Sbjct: 561 DLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRA 620
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI + + RT ++ W ++ +P ++ YN ATV L PW YEFR
Sbjct: 621 GPDNNSPIQIFTIQTRTPFSVGWQAVA-TVPEILNGKTYN----ATV-VGLSPWVEYEFR 674
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G+PS PS T P AP N+ GGGG +L ITW +P LQNG G
Sbjct: 675 VVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGF 734
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y I +R GS + + + +V S +P++VKV +N+ G G S V
Sbjct: 735 GYIIMFRPVGSTTWSKEKVSSVESS--RFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTV 792
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
+YS ED PQ+AP+ S +SF+++ + V+WN I +R G+++G+ + YW ++KE
Sbjct: 793 TIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRN--TGRVLGYEVLYWTDDSKES 850
Query: 479 ---ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPP 535
+ + TT+N I GL+ +T Y+ V A+N+AG GP S T + P +PP
Sbjct: 851 MIGKIRVSGNVTTKN---ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP 907
Query: 536 ASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY 595
A++ W + L + W +V+ E +LGYK+ + Q + +T + A
Sbjct: 908 ANI-AWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILET-----NNTSAE 961
Query: 596 ISNIIP-GKSYNLRVLAYSNGGDGRMS 621
+ ++P + Y + + S+GGDG S
Sbjct: 962 L--LVPFEEDYLIEIRTVSDGGDGSSS 986
Score = 79.8 bits (188), Expect = 3e-14
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 13/203 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A N + + QL + P +++ T+ S N+ +CK P P +TW
Sbjct: 295 YECIASNLRGRNLAKGQL-IFYAPPEWEQKIQN--THLSIYDNLLWECKASGKPNPWYTW 351
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K+ + +R ENG LII L+ D GVY C A+N+Y + L VL AP F
Sbjct: 352 LKNGERLNPE-ERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
Query: 121 LEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
+ + + QV + + C + P A W ++ S +++ ++ G
Sbjct: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFP--RAAISWKRGTETLRQSKRIFL-----LEDGS 463
Query: 180 LTIYNVSLSDVGDYECVVKSAIG 202
L IYN++ SD G Y C+ + G
Sbjct: 464 LKIYNITRSDAGSYTCIATNQFG 486
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 9/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ +V L+C P P +W++ + G ++ L I ++DEG Y C+A
Sbjct: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
N G + ++G+LI P + +K+ + +++++ C A P + Y W NG
Sbjct: 300 SNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLW-ECKASGKP--NPWYTWLKNGE 356
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
R+ +RI+I+ G L I +++SD G Y+C ++ I ++ +LR+
Sbjct: 357 RLNP------EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
Score = 58.4 bits (135), Expect = 8e-08
Identities = 58/210 (27%), Positives = 89/210 (42%), Gaps = 18/210 (8%)
Query: 15 SSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIG-AGG 72
SSA +LS +P F + P + + V L C P P + WK++ I
Sbjct: 16 SSAGDGLLS-RPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMS 74
Query: 73 KRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITA 130
+ + G+L I D D G+Y C+A N GT SR +L F K ++
Sbjct: 75 YHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSV 134
Query: 131 QVNSVVFLHCNADVDPILDTAYLW--NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS 188
+ V L C D +Y W N N L +++ + +V++ + G L I V S
Sbjct: 135 REGQGVVLLCGPP-PHFGDLSYAWTFNDNPLYVQEDNRRFVSQ----ETGNLYIAKVEPS 189
Query: 189 DVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
DVG+Y C + + Q ++GPP P
Sbjct: 190 DVGNYTCFI------TNKEAQRSVQGPPTP 213
Score = 53.2 bits (122), Expect = 3e-06
Identities = 65/231 (28%), Positives = 93/231 (40%), Gaps = 24/231 (10%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
MYQC A N L S A+L+ ++ K + EG V L C P +
Sbjct: 97 MYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSV--REGQGVVLLCGPPPHFGDLS 154
Query: 59 FTWK-KDN-IVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG--RLI 113
+ W DN + + +RF++ E GNL I ++ D G YTC N+ +G +
Sbjct: 155 YAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL 214
Query: 114 VLRA--------PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
V R P+ + P I A +S V L C A +P+ D ++ R D S
Sbjct: 215 VQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISW-------RRLDGS 267
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L + L I N D G YEC+ + GR + QL PP
Sbjct: 268 PLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPP 318
Score = 51.2 bits (117), Expect = 1e-05
Identities = 47/202 (23%), Positives = 83/202 (41%), Gaps = 4/202 (1%)
Query: 428 PQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRT 487
P P+ V +ST ++W + ++ I R + L+
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGK 656
Query: 488 TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNVWAHDPT 546
T N A +VGL P Y +V+A NS G G SE L RT P P +++ +
Sbjct: 657 TYN-ATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRS 715
Query: 547 TLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS-NIIPGKSY 605
L + W + + GY + + + + + + +E Y + +IIP +
Sbjct: 716 ELVITWESIPEELQNGEGFGYIIMFRPVGST-TWSKEKVSSVESSRFVYRNESIIPLSPF 774
Query: 606 NLRVLAYSNGGDGRMSSPTIAF 627
++V Y+N G+G +S+ TI +
Sbjct: 775 EVKVGVYNNEGEGSLSTVTIVY 796
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 350 bits (860), Expect = 1e-95
Identities = 204/627 (32%), Positives = 329/627 (52%), Gaps = 29/627 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ + Y++A+LRVL+ P F K P++ +++ GG++ + CKP A P+ +
Sbjct: 383 VYQCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAIS 442
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WK+ + + F+ E+G+L I ++R D G YTC+A NQ+GT ++ G LIV R
Sbjct: 443 WKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIV--KERT 500
Query: 121 LEKLPP-RITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-G 178
+ +PP ++ V + L C DP ++ ++W NG I + +RI + G
Sbjct: 501 VITVPPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVG 560
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ + +S+ + + GPPGPP VQ+ I ++ L W
Sbjct: 561 DLMIRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRA 620
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N PI + + RT ++ W ++ +P ++ YN ATV L PW YEFR
Sbjct: 621 GPDNNSPIQIFTIQTRTPFSVGWQAVA-TVPEILNGKTYN----ATV-VGLSPWVEYEFR 674
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G+PS PS T P AP N+ GGGG +L ITW +P LQNG G
Sbjct: 675 VVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGF 734
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y I +R GS + + + +V S +P++VKV +N+ G G S V
Sbjct: 735 GYIIMFRPVGSTTWSKEKVSSVESS--RFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTV 792
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
+YS ED PQ+AP+ S +SF+++ + V+WN I +R G+++G+ + YW ++KE
Sbjct: 793 TIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRN--TGRVLGYEVLYWTDDSKES 850
Query: 479 ---ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPP 535
+ + TT+N I GL+ +T Y+ V A+N+AG GP S T + P +PP
Sbjct: 851 MIGKIRVSGNVTTKN---ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPP 907
Query: 536 ASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY 595
A++ W + L + W +V+ E +LGYK+ + Q + +T + A
Sbjct: 908 ANI-AWKLTNSKLCLNWEHVKTMENESEVLGYKILYRQNRQSKTHILET-----NNTSAE 961
Query: 596 ISNIIP-GKSYNLRVLAYSNGGDGRMS 621
+ ++P + Y + + S+GGDG S
Sbjct: 962 L--LVPFEEDYLIEIRTVSDGGDGSSS 986
Score = 79.8 bits (188), Expect = 3e-14
Identities = 57/203 (28%), Positives = 92/203 (45%), Gaps = 13/203 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A N + + QL + P +++ T+ S N+ +CK P P +TW
Sbjct: 295 YECIASNLRGRNLAKGQL-IFYAPPEWEQKIQN--THLSIYDNLLWECKASGKPNPWYTW 351
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K+ + +R ENG LII L+ D GVY C A+N+Y + L VL AP F
Sbjct: 352 LKNGERLNPE-ERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLASAPDF 410
Query: 121 LEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
+ + + QV + + C + P A W ++ S +++ ++ G
Sbjct: 411 SKSPVKKKSFVQVGGDIVIGCKPNAFP--RAAISWKRGTETLRQSKRIFL-----LEDGS 463
Query: 180 LTIYNVSLSDVGDYECVVKSAIG 202
L IYN++ SD G Y C+ + G
Sbjct: 464 LKIYNITRSDAGSYTCIATNQFG 486
Score = 67.7 bits (158), Expect = 1e-10
Identities = 44/173 (25%), Positives = 85/173 (49%), Gaps = 9/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ +V L+C P P +W++ + G ++ L I ++DEG Y C+A
Sbjct: 240 AKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIA 299
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
N G + ++G+LI P + +K+ + +++++ C A P + Y W NG
Sbjct: 300 SNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLW-ECKASGKP--NPWYTWLKNGE 356
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
R+ +RI+I+ G L I +++SD G Y+C ++ I ++ +LR+
Sbjct: 357 RLNP------EERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
Score = 58.4 bits (135), Expect = 8e-08
Identities = 58/210 (27%), Positives = 89/210 (42%), Gaps = 18/210 (8%)
Query: 15 SSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIG-AGG 72
SSA +LS +P F + P + + V L C P P + WK++ I
Sbjct: 16 SSAGDGLLS-RPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMS 74
Query: 73 KRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITA 130
+ + G+L I D D G+Y C+A N GT SR +L F K ++
Sbjct: 75 YHYRLDGGSLAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSV 134
Query: 131 QVNSVVFLHCNADVDPILDTAYLW--NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS 188
+ V L C D +Y W N N L +++ + +V++ + G L I V S
Sbjct: 135 REGQGVVLLCGPP-PHFGDLSYAWTFNDNPLYVQEDNRRFVSQ----ETGNLYIAKVEPS 189
Query: 189 DVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
DVG+Y C + + Q ++GPP P
Sbjct: 190 DVGNYTCFI------TNKEAQRSVQGPPTP 213
Score = 53.2 bits (122), Expect = 3e-06
Identities = 65/231 (28%), Positives = 93/231 (40%), Gaps = 24/231 (10%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
MYQC A N L S A+L+ ++ K + EG V L C P +
Sbjct: 97 MYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSV--REGQGVVLLCGPPPHFGDLS 154
Query: 59 FTWK-KDN-IVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG--RLI 113
+ W DN + + +RF++ E GNL I ++ D G YTC N+ +G +
Sbjct: 155 YAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPL 214
Query: 114 VLRA--------PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
V R P+ + P I A +S V L C A +P+ D ++ R D S
Sbjct: 215 VQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISW-------RRLDGS 267
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L + L I N D G YEC+ + GR + QL PP
Sbjct: 268 PLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPP 318
Score = 51.2 bits (117), Expect = 1e-05
Identities = 47/202 (23%), Positives = 83/202 (41%), Gaps = 4/202 (1%)
Query: 428 PQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRT 487
P P+ V +ST ++W + ++ I R + L+
Sbjct: 597 PPGPPEDVQVEDISSTTSQLSWRAGPDNNSPIQIFTIQTRTPFSVGWQAVATVPEILNGK 656
Query: 488 TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNVWAHDPT 546
T N A +VGL P Y +V+A NS G G SE L RT P P +++ +
Sbjct: 657 TYN-ATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRS 715
Query: 547 TLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS-NIIPGKSY 605
L + W + + GY + + + + + + +E Y + +IIP +
Sbjct: 716 ELVITWESIPEELQNGEGFGYIIMFRPVGST-TWSKEKVSSVESSRFVYRNESIIPLSPF 774
Query: 606 NLRVLAYSNGGDGRMSSPTIAF 627
++V Y+N G+G +S+ TI +
Sbjct: 775 EVKVGVYNNEGEGSLSTVTIVY 796
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 348 bits (855), Expect = 4e-95
Identities = 208/629 (33%), Positives = 327/629 (51%), Gaps = 26/629 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N A Y++A+L++L+L P+F+ +P++ + ++GG V ++CKP+AAPKP F+
Sbjct: 377 MYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFS 436
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K + + I E+G+L I ++R+D G+YTC A+N G S G L++ R
Sbjct: 437 WSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 496
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK-DSSDLYVNKRIKID-GG 178
+ P V + C A DP LD ++W+ NG I + +++ + +D G
Sbjct: 497 I-LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG 555
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
EL I N L G Y C ++ + S+ L + GPPGPPGG++I I+ +SV L W+
Sbjct: 556 ELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSR 615
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y + +T + W ++ P ++E G A + L+PW YEFR
Sbjct: 616 GSDNHSPISKYTIQTKTILSDDW-KDAKTDPPIIE-----GNMEAARAVDLIPWMEYEFR 669
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N LG G+PS PS + T G P AP++V GGGG+ +LTITW PL G
Sbjct: 670 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNF 729
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + ++ E E++ + + + G YV + T + VKV+AFN+ G GP S V
Sbjct: 730 GYIVAFKPFDGE-EWKKVTVTN-PDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLV 787
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI-GHRLKYWKQENKE 477
I SA+D P AP V + +S+ ++V W E + K++ ++++YW +KE
Sbjct: 788 AVINSAQDAPSEAPTEVGVKVLSSSEISVHW-------EHVLEKIVESYQIRYWAAHDKE 840
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
E + A + L PDT Y+++V A NSAG GP S+ +E +KAP P
Sbjct: 841 EAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSD-MIEAFTKKAPPSQPPR 899
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
+ + + W +V + E + GYKV L+ D +D + HK +
Sbjct: 900 IISSVRSGSRYIITWDHVVALSNESTVTGYKV-LYRPDGQ----HDGKLYSTHKHSIEVP 954
Query: 598 NIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
G+ Y + V A+S+GGDG +S I+
Sbjct: 955 IPRDGE-YVVEVRAHSDGGDGVVSQVKIS 982
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Query: 26 PSFKKHPLELETYGSEG--GNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI 83
P F++ P+ Y E G V+L C+ A+P P + W+ +N + R+ GNL+
Sbjct: 30 PIFEEQPINT-IYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 88
Query: 84 IRQLSRD-DEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
I + D G+Y C+A N YG S L F + P + + + L C+
Sbjct: 89 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 148
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
D +Y W N + + D + + G L I NV SD G+Y C V S
Sbjct: 149 PPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 204
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 20/178 (11%)
Query: 36 ETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGV 94
+ Y G NVTL+C P P W+K ++ I+ +G ++ I + +DEG+
Sbjct: 239 DVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGI 296
Query: 95 YTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
Y C A+N G D+ + R+ V P ++E + + S ++ C A PI W
Sbjct: 297 YECEAENIRGKDKHQARIYVQAFPEWVEHIND-TEVDIGSDLYWPCVATGKPI--PTIRW 353
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
NG Y + GEL +Y+V+ + G Y+C+ ++ G I ++ +L+I
Sbjct: 354 LKNG---------YAYHK-----GELRLYDVTFENAGMYQCIAENTYGAIYANAELKI 397
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 23/218 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+CEA+N A++ V + P + +H + E G ++ C P PT
Sbjct: 296 IYECEAENIRGKDKHQARIYVQAF-PEWVEHINDTEV--DIGSDLYWPCVATGKPIPTIR 352
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + G L + ++ ++ G+Y C+A+N YG + L +L AP
Sbjct: 353 WLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPT 403
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F + + +I A V + C P + W+ K + L + RI I +
Sbjct: 404 FEMNPMKKKILAAKGGRVIIECKPKAAP--KPKFSWS------KGTEWLVNSSRILIWED 455
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N++ +D G Y C ++ G+ +S L I P
Sbjct: 456 GSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDP 493
Score = 44.4 bits (100), Expect = 0.001
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 41 EGGNVTLKCKP--EAAPKPTFTWKKDN--IVIGAGGKRFITE-NGNLIIRQLSRDDEGVY 95
EG + L C P ++ W + + I +RF+++ NGNL I + D+G Y
Sbjct: 139 EGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNY 198
Query: 96 TCVAKNQYGTDESRGRLI-VLRAP-RFLEKLPPRITAQVNSV-------VFLHCNADVDP 146
+C + T + I ++ P R + P I Q V V L C A +P
Sbjct: 199 SCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNP 258
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ D W K + I G L I+N+ L D G YEC ++ G+
Sbjct: 259 VPDIR--WR------KVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKH 310
Query: 207 HVQLRIEGPP 216
++ ++ P
Sbjct: 311 QARIYVQAFP 320
Score = 33.9 bits (74), Expect = 1.9
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 1/146 (0%)
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRV 550
A V L P Y +V+A N+ G G P +T AP P+ V L +
Sbjct: 655 ARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTI 714
Query: 551 VWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVL 610
W + GY V D + P + + P ++ ++V
Sbjct: 715 TWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVK 774
Query: 611 AYSNGGDGRMSSPTIAFQIGDYHSEA 636
A++N GDG S + D SEA
Sbjct: 775 AFNNKGDGPYSLVAVINSAQDAPSEA 800
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 348 bits (855), Expect = 4e-95
Identities = 208/629 (33%), Positives = 327/629 (51%), Gaps = 26/629 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N A Y++A+L++L+L P+F+ +P++ + ++GG V ++CKP+AAPKP F+
Sbjct: 388 MYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFS 447
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K + + I E+G+L I ++R+D G+YTC A+N G S G L++ R
Sbjct: 448 WSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 507
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK-DSSDLYVNKRIKID-GG 178
+ P V + C A DP LD ++W+ NG I + +++ + +D G
Sbjct: 508 I-LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG 566
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
EL I N L G Y C ++ + S+ L + GPPGPPGG++I I+ +SV L W+
Sbjct: 567 ELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSR 626
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y + +T + W ++ P ++E G A + L+PW YEFR
Sbjct: 627 GSDNHSPISKYTIQTKTILSDDW-KDAKTDPPIIE-----GNMEAARAVDLIPWMEYEFR 680
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N LG G+PS PS + T G P AP++V GGGG+ +LTITW PL G
Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNF 740
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + ++ E E++ + + + G YV + T + VKV+AFN+ G GP S V
Sbjct: 741 GYIVAFKPFDGE-EWKKVTVTN-PDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLV 798
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI-GHRLKYWKQENKE 477
I SA+D P AP V + +S+ ++V W E + K++ ++++YW +KE
Sbjct: 799 AVINSAQDAPSEAPTEVGVKVLSSSEISVHW-------EHVLEKIVESYQIRYWAAHDKE 851
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
E + A + L PDT Y+++V A NSAG GP S+ +E +KAP P
Sbjct: 852 EAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSD-MIEAFTKKAPPSQPPR 910
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
+ + + W +V + E + GYKV L+ D +D + HK +
Sbjct: 911 IISSVRSGSRYIITWDHVVALSNESTVTGYKV-LYRPDGQ----HDGKLYSTHKHSIEVP 965
Query: 598 NIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
G+ Y + V A+S+GGDG +S I+
Sbjct: 966 IPRDGE-YVVEVRAHSDGGDGVVSQVKIS 993
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Query: 26 PSFKKHPLELETYGSEG--GNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI 83
P F++ P+ Y E G V+L C+ A+P P + W+ +N + R+ GNL+
Sbjct: 41 PIFEEQPINT-IYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
Query: 84 IRQLSRD-DEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
I + D G+Y C+A N YG S L F + P + + + L C+
Sbjct: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
D +Y W N + + D + + G L I NV SD G+Y C V S
Sbjct: 160 PPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 20/178 (11%)
Query: 36 ETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGV 94
+ Y G NVTL+C P P W+K ++ I+ +G ++ I + +DEG+
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGI 307
Query: 95 YTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
Y C A+N G D+ + R+ V P ++E + + S ++ C A PI W
Sbjct: 308 YECEAENIRGKDKHQARIYVQAFPEWVEHIND-TEVDIGSDLYWPCVATGKPI--PTIRW 364
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
NG Y + GEL +Y+V+ + G Y+C+ ++ G I ++ +L+I
Sbjct: 365 LKNG---------YAYHK-----GELRLYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 23/218 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+CEA+N A++ V + P + +H + E G ++ C P PT
Sbjct: 307 IYECEAENIRGKDKHQARIYVQAF-PEWVEHINDTEV--DIGSDLYWPCVATGKPIPTIR 363
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + G L + ++ ++ G+Y C+A+N YG + L +L AP
Sbjct: 364 WLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPT 414
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F + + +I A V + C P + W+ K + L + RI I +
Sbjct: 415 FEMNPMKKKILAAKGGRVIIECKPKAAP--KPKFSWS------KGTEWLVNSSRILIWED 466
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N++ +D G Y C ++ G+ +S L I P
Sbjct: 467 GSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDP 504
Score = 44.4 bits (100), Expect = 0.001
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 41 EGGNVTLKCKP--EAAPKPTFTWKKDN--IVIGAGGKRFITE-NGNLIIRQLSRDDEGVY 95
EG + L C P ++ W + + I +RF+++ NGNL I + D+G Y
Sbjct: 150 EGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNY 209
Query: 96 TCVAKNQYGTDESRGRLI-VLRAP-RFLEKLPPRITAQVNSV-------VFLHCNADVDP 146
+C + T + I ++ P R + P I Q V V L C A +P
Sbjct: 210 SCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNP 269
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ D W K + I G L I+N+ L D G YEC ++ G+
Sbjct: 270 VPDIR--WR------KVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKH 321
Query: 207 HVQLRIEGPP 216
++ ++ P
Sbjct: 322 QARIYVQAFP 331
Score = 33.9 bits (74), Expect = 1.9
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 1/146 (0%)
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRV 550
A V L P Y +V+A N+ G G P +T AP P+ V L +
Sbjct: 666 ARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTI 725
Query: 551 VWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVL 610
W + GY V D + P + + P ++ ++V
Sbjct: 726 TWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVK 785
Query: 611 AYSNGGDGRMSSPTIAFQIGDYHSEA 636
A++N GDG S + D SEA
Sbjct: 786 AFNNKGDGPYSLVAVINSAQDAPSEA 811
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 347 bits (852), Expect = 1e-94
Identities = 207/629 (32%), Positives = 327/629 (51%), Gaps = 26/629 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N A Y++A+L++L+L P+F+ +P++ + ++GG V ++CKP+AAPKP F+
Sbjct: 388 MYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFS 447
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K + + I E+G+L I ++R+D G+YTC A+N G S G L++ R
Sbjct: 448 WSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 507
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK-DSSDLYVNKRIKID-GG 178
+ P V + C A DP LD ++W+ NG I + +++ + +D G
Sbjct: 508 I-LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG 566
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
EL I N L G Y C ++ + S+ L + GPPGPPGG++I I+ +SV L W+
Sbjct: 567 ELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSR 626
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y + +T + W ++ P ++E G A + L+PW YEFR
Sbjct: 627 GSDNHSPISKYTIQTKTILSDDW-KDAKTDPPIIE-----GNMEAARAVDLIPWMEYEFR 680
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N LG G+PS PS + T G P AP++V GGGG+ +LTITW PL G
Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNF 740
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + ++ E E++ + + + G YV + T + VKV+AFN+ G GP S +
Sbjct: 741 GYIVAFKPFDGE-EWKKVTVTN-PDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLL 798
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI-GHRLKYWKQENKE 477
I SA+D P AP V + +S+ ++V W E + K++ ++++YW +KE
Sbjct: 799 AVINSAQDAPSEAPTEVGVKVLSSSEISVHW-------EHVLEKIVESYQIRYWAAHDKE 851
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
E + A + L PDT Y+++V A NSAG GP S+ +E +KAP P
Sbjct: 852 EAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSD-MIEAFTKKAPPSQPPR 910
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
+ + + W +V + E + GYKV L+ D +D + HK +
Sbjct: 911 IISSVRSGSRYIITWDHVVALSNESTVTGYKV-LYRPDGQ----HDGKLYSTHKHSIEVP 965
Query: 598 NIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
G+ Y + V A+S+GGDG +S I+
Sbjct: 966 IPRDGE-YVVEVRAHSDGGDGVVSQVKIS 993
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Query: 26 PSFKKHPLELETYGSEG--GNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI 83
P F++ P+ Y E G V+L C+ A+P P + W+ +N + R+ GNL+
Sbjct: 41 PIFEEQPINT-IYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
Query: 84 IRQLSRD-DEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
I + D G+Y C+A N YG S L F + P + + + L C+
Sbjct: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
D +Y W N + + D + + G L I NV SD G+Y C V S
Sbjct: 160 PPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 20/178 (11%)
Query: 36 ETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGV 94
+ Y G NVTL+C P P W+K ++ I+ +G ++ I + +DEG+
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGI 307
Query: 95 YTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
Y C A+N G D+ + R+ V P ++E + + S ++ C A PI W
Sbjct: 308 YECEAENIRGKDKHQARIYVQAFPEWVEHIND-TEVDIGSDLYWPCVATGKPI--PTIRW 364
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
NG Y + GEL +Y+V+ + G Y+C+ ++ G I ++ +L+I
Sbjct: 365 LKNG---------YAYHK-----GELRLYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 23/218 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+CEA+N A++ V + P + +H + E G ++ C P PT
Sbjct: 307 IYECEAENIRGKDKHQARIYVQAF-PEWVEHINDTEV--DIGSDLYWPCVATGKPIPTIR 363
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + G L + ++ ++ G+Y C+A+N YG + L +L AP
Sbjct: 364 WLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPT 414
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F + + +I A V + C P + W+ K + L + RI I +
Sbjct: 415 FEMNPMKKKILAAKGGRVIIECKPKAAP--KPKFSWS------KGTEWLVNSSRILIWED 466
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N++ +D G Y C ++ G+ +S L I P
Sbjct: 467 GSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDP 504
Score = 44.4 bits (100), Expect = 0.001
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 41 EGGNVTLKCKP--EAAPKPTFTWKKDN--IVIGAGGKRFITE-NGNLIIRQLSRDDEGVY 95
EG + L C P ++ W + + I +RF+++ NGNL I + D+G Y
Sbjct: 150 EGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNY 209
Query: 96 TCVAKNQYGTDESRGRLI-VLRAP-RFLEKLPPRITAQVNSV-------VFLHCNADVDP 146
+C + T + I ++ P R + P I Q V V L C A +P
Sbjct: 210 SCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNP 269
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ D W K + I G L I+N+ L D G YEC ++ G+
Sbjct: 270 VPDIR--WR------KVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKH 321
Query: 207 HVQLRIEGPP 216
++ ++ P
Sbjct: 322 QARIYVQAFP 331
Score = 33.5 bits (73), Expect = 2.5
Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 1/146 (0%)
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRV 550
A V L P Y +V+A N+ G G P +T AP P+ V L +
Sbjct: 666 ARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTI 725
Query: 551 VWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVL 610
W + GY V D + P + + P ++ ++V
Sbjct: 726 TWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVK 785
Query: 611 AYSNGGDGRMSSPTIAFQIGDYHSEA 636
A++N GDG S + D SEA
Sbjct: 786 AFNNKGDGPYSLLAVINSAQDAPSEA 811
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 337 bits (829), Expect = 6e-92
Identities = 196/624 (31%), Positives = 312/624 (50%), Gaps = 22/624 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ A Y+SA+L++L+ P+F + L+ ++ V ++CKP+ +PKPT +
Sbjct: 455 MYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTIS 514
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK + + + I +G+L I S+ DEG Y C +N +G+ E L V + P
Sbjct: 515 WKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSV-KEPTR 573
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG--LRIKDSSDLYVNKRIKIDGG 178
+E P R V + L+C A D LD + W G + ++ + + R +
Sbjct: 574 IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSA 633
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ +S +L + GPPGPPG V + I S+ TL W+
Sbjct: 634 DLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSP 693
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y L R+ ++ W + + +P ++ G + ++ L PW YEFR
Sbjct: 694 AADNHSPISSYNLQARSPFSLGWQTV-KTVPEII-----TGDMESAMAVDLNPWVEYEFR 747
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G PS PS T+ P AP NVSG G+ +L I W P+ QNG G
Sbjct: 748 VVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGF 807
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R NG+ + ++ ++ S TP++VKV +N+ G GP S++
Sbjct: 808 GYIVAFRPNGTRGWKEKMVTS--SEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQI 865
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
V I SAE P AP V A S + + + V W I +S R +G +G YWK +E+
Sbjct: 866 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVG----YWKDMEQED 921
Query: 479 ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASV 538
+R ++ ++ GL+ +T Y+ V A+N AG GP S T + P + P+++
Sbjct: 922 TAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNL 981
Query: 539 NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISN 598
W + + + W V P E ++GYKV + +N ++ + KL+A +
Sbjct: 982 R-WEQQGSQVSLGWEPVIPLANESEVVGYKV----FYRQEGHSNSQVIETQ-KLQAVVP- 1034
Query: 599 IIPGKSYNLRVLAYSNGGDGRMSS 622
+ Y + V AYS GGDG SS
Sbjct: 1035 LPDAGVYIIEVRAYSEGGDGTASS 1058
Score = 78.2 bits (184), Expect = 9e-14
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + QL+V + +K +T G + +CK P+PT+
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYTYPHWVEKLN---DTQLDSGSPLRWECKATGKPRPTYR 422
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL-IVLRAPR 119
W K+ + + R NG L+I +++ D G+Y C+A+N+YG + L I+ AP
Sbjct: 423 WLKNGVPLSPQS-RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPT 481
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L +L I + V + C P W +++ NKRI I
Sbjct: 482 FALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWKKGDRAVRE------NKRIAILPD 533
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N S SD G Y C ++ G L ++ P
Sbjct: 534 GSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEP 571
Score = 77.8 bits (183), Expect = 1e-13
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 10/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++G V ++C P PT TW K N I + R L I + DD G+Y C A
Sbjct: 313 AKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-RLRKSQAVLEIPNVQLDDAGIYECRA 371
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
+N G + RG+L V P ++EKL S + C A P Y W NG+
Sbjct: 372 ENSRGKNSFRGQLQVYTYPHWVEKLNDT-QLDSGSPLRWECKATGKP--RPTYRWLKNGV 428
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ S R+++ G L I+NV+ SD G Y+C+ ++ G I + +L+I
Sbjct: 429 PLSPQS------RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 475
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 14/183 (7%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGNLIIRQLSR-DDEGVYTC 97
S+ V L C+ P P++ W ++ I R+ +G II S D G Y C
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 98 VAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADV-DPILDTAYLWN 155
+A N G+ SR L F + ++ + V L C+ P + ++++N
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFN 233
Query: 156 HNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
+ + S ++++ + G L I V SDVG Y C+VK+ + R+ P
Sbjct: 234 EFPSFVAEDSRRFISQ----ETGNLYISKVQTSDVGSYICLVKNTV------TNARVLSP 283
Query: 216 PGP 218
P P
Sbjct: 284 PTP 286
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 337 bits (829), Expect = 6e-92
Identities = 196/624 (31%), Positives = 312/624 (50%), Gaps = 22/624 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ A Y+SA+L++L+ P+F + L+ ++ V ++CKP+ +PKPT +
Sbjct: 381 MYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTIS 440
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK + + + I +G+L I S+ DEG Y C +N +G+ E L V + P
Sbjct: 441 WKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSV-KEPTR 499
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG--LRIKDSSDLYVNKRIKIDGG 178
+E P R V + L+C A D LD + W G + ++ + + R +
Sbjct: 500 IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSA 559
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ +S +L + GPPGPPG V + I S+ TL W+
Sbjct: 560 DLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSP 619
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y L R+ ++ W + + +P ++ G + ++ L PW YEFR
Sbjct: 620 AADNHSPISSYNLQARSPFSLGWQTV-KTVPEII-----TGDMESAMAVDLNPWVEYEFR 673
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G PS PS T+ P AP NVSG G+ +L I W P+ QNG G
Sbjct: 674 VVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGF 733
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R NG+ + ++ ++ S TP++VKV +N+ G GP S++
Sbjct: 734 GYIVAFRPNGTRGWKEKMVTS--SEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQI 791
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
V I SAE P AP V A S + + + V W I +S R +G +G YWK +E+
Sbjct: 792 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVG----YWKDMEQED 847
Query: 479 ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASV 538
+R ++ ++ GL+ +T Y+ V A+N AG GP S T + P + P+++
Sbjct: 848 TAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNL 907
Query: 539 NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISN 598
W + + + W V P E ++GYKV + +N ++ + KL+A +
Sbjct: 908 R-WEQQGSQVSLGWEPVIPLANESEVVGYKV----FYRQEGHSNSQVIETQ-KLQAVVP- 960
Query: 599 IIPGKSYNLRVLAYSNGGDGRMSS 622
+ Y + V AYS GGDG SS
Sbjct: 961 LPDAGVYIIEVRAYSEGGDGTASS 984
Score = 78.2 bits (184), Expect = 9e-14
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + QL+V + +K +T G + +CK P+PT+
Sbjct: 292 IYECRAENSRGKNSFRGQLQVYTYPHWVEKLN---DTQLDSGSPLRWECKATGKPRPTYR 348
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL-IVLRAPR 119
W K+ + + R NG L+I +++ D G+Y C+A+N+YG + L I+ AP
Sbjct: 349 WLKNGVPLSPQS-RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPT 407
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L +L I + V + C P W +++ NKRI I
Sbjct: 408 FALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWKKGDRAVRE------NKRIAILPD 459
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N S SD G Y C ++ G L ++ P
Sbjct: 460 GSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEP 497
Score = 77.8 bits (183), Expect = 1e-13
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 10/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++G V ++C P PT TW K N I + R L I + DD G+Y C A
Sbjct: 239 AKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-RLRKSQAVLEIPNVQLDDAGIYECRA 297
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
+N G + RG+L V P ++EKL S + C A P Y W NG+
Sbjct: 298 ENSRGKNSFRGQLQVYTYPHWVEKLNDT-QLDSGSPLRWECKATGKP--RPTYRWLKNGV 354
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ S R+++ G L I+NV+ SD G Y+C+ ++ G I + +L+I
Sbjct: 355 PLSPQS------RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 401
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 14/183 (7%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGNLIIRQLSR-DDEGVYTC 97
S+ V L C+ P P++ W ++ I R+ +G II S D G Y C
Sbjct: 40 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 99
Query: 98 VAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADV-DPILDTAYLWN 155
+A N G+ SR L F + ++ + V L C+ P + ++++N
Sbjct: 100 LATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFN 159
Query: 156 HNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
+ + S ++++ + G L I V SDVG Y C+VK+ + R+ P
Sbjct: 160 EFPSFVAEDSRRFISQ----ETGNLYISKVQTSDVGSYICLVKNTV------TNARVLSP 209
Query: 216 PGP 218
P P
Sbjct: 210 PTP 212
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 337 bits (829), Expect = 6e-92
Identities = 196/624 (31%), Positives = 312/624 (50%), Gaps = 22/624 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ A Y+SA+L++L+ P+F + L+ ++ V ++CKP+ +PKPT +
Sbjct: 455 MYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTIS 514
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK + + + I +G+L I S+ DEG Y C +N +G+ E L V + P
Sbjct: 515 WKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSV-KEPTR 573
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG--LRIKDSSDLYVNKRIKIDGG 178
+E P R V + L+C A D LD + W G + ++ + + R +
Sbjct: 574 IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSA 633
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ +S +L + GPPGPPG V + I S+ TL W+
Sbjct: 634 DLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSP 693
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y L R+ ++ W + + +P ++ G + ++ L PW YEFR
Sbjct: 694 AADNHSPISSYNLQARSPFSLGWQTV-KTVPEII-----TGDMESAMAVDLNPWVEYEFR 747
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G PS PS T+ P AP NVSG G+ +L I W P+ QNG G
Sbjct: 748 VVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGF 807
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R NG+ + ++ ++ S TP++VKV +N+ G GP S++
Sbjct: 808 GYIVAFRPNGTRGWKEKMVTS--SEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQI 865
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
V I SAE P AP V A S + + + V W I +S R +G +G YWK +E+
Sbjct: 866 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVG----YWKDMEQED 921
Query: 479 ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASV 538
+R ++ ++ GL+ +T Y+ V A+N AG GP S T + P + P+++
Sbjct: 922 TAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNL 981
Query: 539 NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISN 598
W + + + W V P E ++GYKV + +N ++ + KL+A +
Sbjct: 982 R-WEQQGSQVSLGWEPVIPLANESEVVGYKV----FYRQEGHSNSQVIETQ-KLQAVVP- 1034
Query: 599 IIPGKSYNLRVLAYSNGGDGRMSS 622
+ Y + V AYS GGDG SS
Sbjct: 1035 LPDAGVYIIEVRAYSEGGDGTASS 1058
Score = 78.2 bits (184), Expect = 9e-14
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + QL+V + +K +T G + +CK P+PT+
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYTYPHWVEKLN---DTQLDSGSPLRWECKATGKPRPTYR 422
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL-IVLRAPR 119
W K+ + + R NG L+I +++ D G+Y C+A+N+YG + L I+ AP
Sbjct: 423 WLKNGVPLSPQS-RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPT 481
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L +L I + V + C P W +++ NKRI I
Sbjct: 482 FALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWKKGDRAVRE------NKRIAILPD 533
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N S SD G Y C ++ G L ++ P
Sbjct: 534 GSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEP 571
Score = 77.8 bits (183), Expect = 1e-13
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 10/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++G V ++C P PT TW K N I + R L I + DD G+Y C A
Sbjct: 313 AKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-RLRKSQAVLEIPNVQLDDAGIYECRA 371
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
+N G + RG+L V P ++EKL S + C A P Y W NG+
Sbjct: 372 ENSRGKNSFRGQLQVYTYPHWVEKLNDT-QLDSGSPLRWECKATGKP--RPTYRWLKNGV 428
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ S R+++ G L I+NV+ SD G Y+C+ ++ G I + +L+I
Sbjct: 429 PLSPQS------RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 475
Score = 50.4 bits (115), Expect = 2e-05
Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 14/183 (7%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGNLIIRQLSR-DDEGVYTC 97
S+ V L C+ P P++ W ++ I R+ +G II S D G Y C
Sbjct: 114 SDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQC 173
Query: 98 VAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADV-DPILDTAYLWN 155
+A N G+ SR L F + ++ + V L C+ P + ++++N
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPEIIYSWVFN 233
Query: 156 HNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
+ + S ++++ + G L I V SDVG Y C+VK+ + R+ P
Sbjct: 234 EFPSFVAEDSRRFISQ----ETGNLYISKVQTSDVGSYICLVKNTV------TNARVLSP 283
Query: 216 PGP 218
P P
Sbjct: 284 PTP 286
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 273 bits (670), Expect = 1e-72
Identities = 151/463 (32%), Positives = 236/463 (50%), Gaps = 11/463 (2%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N+ A Y+SA+L++L+ P+F + L+ ++ V ++CKP+ +PKPT +
Sbjct: 161 MYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTIS 220
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
WKK + + + I +G+L I S+ DEG Y C +N +G+ E L V + P
Sbjct: 221 WKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSV-KEPTR 279
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG--LRIKDSSDLYVNKRIKIDGG 178
+E P R V + L+C A D LD + W G + ++ + + R +
Sbjct: 280 IELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSA 339
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
+L I N+ L G Y C V++ +S +L + GPPGPPG V + I S+ TL W+
Sbjct: 340 DLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLSWSP 399
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
+ N PI+ Y L R+ ++ W + + +P ++ G + ++ L PW YEFR
Sbjct: 400 AADNHSPISSYNLQARSPFSLGWQTV-KTVPEII-----TGDMESAMAVDLNPWVEYEFR 453
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A N +G G PS PS T+ P AP NVSG G+ +L I W P+ QNG G
Sbjct: 454 VVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGF 513
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + +R NG+ + ++ ++ S TP++VKV +N+ G GP S++
Sbjct: 514 GYIVAFRPNGTRGWKEKMVTS--SEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQI 571
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRG 461
V I SAE P AP V A S + + + V W I +S R +G
Sbjct: 572 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQG 614
Score = 78.2 bits (184), Expect = 9e-14
Identities = 60/218 (27%), Positives = 95/218 (43%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A+N + QL+V + +K +T G + +CK P+PT+
Sbjct: 72 IYECRAENSRGKNSFRGQLQVYTYPHWVEKLN---DTQLDSGSPLRWECKATGKPRPTYR 128
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL-IVLRAPR 119
W K+ + + R NG L+I +++ D G+Y C+A+N+YG + L I+ AP
Sbjct: 129 WLKNGVPLSPQS-RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPT 187
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F L +L I + V + C P W +++ NKRI I
Sbjct: 188 FALNQLKKTIIVTKDQEVVIECKPQGSP--KPTISWKKGDRAVRE------NKRIAILPD 239
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N S SD G Y C ++ G L ++ P
Sbjct: 240 GSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEP 277
Score = 77.8 bits (183), Expect = 1e-13
Identities = 54/173 (31%), Positives = 81/173 (46%), Gaps = 10/173 (5%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++G V ++C P PT TW K N I + R L I + DD G+Y C A
Sbjct: 19 AKGTTVKMECFALGNPVPTITWMKVNGYIPSKA-RLRKSQAVLEIPNVQLDDAGIYECRA 77
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
+N G + RG+L V P ++EKL S + C A P Y W NG+
Sbjct: 78 ENSRGKNSFRGQLQVYTYPHWVEKLNDT-QLDSGSPLRWECKATGKP--RPTYRWLKNGV 134
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ S R+++ G L I+NV+ SD G Y+C+ ++ G I + +L+I
Sbjct: 135 PLSPQS------RVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 181
Score = 54.4 bits (125), Expect = 1e-06
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 4/162 (2%)
Query: 397 YTPYDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQS 455
+ Y+ +V A N IG G P + I + E +P+ AP VS RS L + W P+ S
Sbjct: 447 WVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPV--S 504
Query: 456 RERLRGKLIGHRLKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAG 514
E G+ G+ + + + +E + S ++ + P T + VKV +N+ G
Sbjct: 505 EEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKG 564
Query: 515 EGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQ 556
+GP S+ + + P P V + + + V W++++
Sbjct: 565 DGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK 606
Score = 34.3 bits (75), Expect = 1.4
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 3/132 (2%)
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRV 550
A+ V L P Y +V+A N G G P + + RT P+ P +V+ + L +
Sbjct: 439 AMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVI 498
Query: 551 VWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKS-YNLRV 609
W V + GY V + + + E Y +P + + ++V
Sbjct: 499 AWEPVSEEFQNGEGFGYIV-AFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKV 557
Query: 610 LAYSNGGDGRMS 621
Y+N GDG S
Sbjct: 558 GVYNNKGDGPFS 569
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 255 bits (625), Expect = 3e-67
Identities = 180/634 (28%), Positives = 302/634 (47%), Gaps = 43/634 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
+YQCEA N ++A + V+ ++P + + E Y + G + L C+ A+P+
Sbjct: 398 VYQCEASNVHGTILANANIDVVDVRPLIQTK--DGENYATVVGYSAFLHCEFFASPEAVV 455
Query: 60 TWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+K V G+R+ I ENG L I + + +D G Y+C +N G L + A
Sbjct: 456 SWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNAT 515
Query: 119 RF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYL--WNHNGLRIKDSSDLYVNKRIKI 175
+ + PRI ++ LHC + D L + W+ +G + + + RI I
Sbjct: 516 KLRVSPKNPRIPKL--HMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGT--EDGRIII 571
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLE 235
DG LTI NV+L D G Y C +A+ + Q+ + P PP + + Q SV L
Sbjct: 572 DGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLT 631
Query: 236 WTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
W + I+ Y++ + E E+ R G+K TV L P+ Y
Sbjct: 632 WEAGADHNSNISEYIVEFEGN--------KEEPGRWEELTRVQGKK-TTVILPLAPFVRY 682
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ A+N +G QPS PS T P P N+ + ++ I W PL + QNG
Sbjct: 683 QFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNG 742
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
PG+ Y++ W+ G+ VE++ + + + + + Y PYDVKVQA N +G GP+
Sbjct: 743 PGLEYRVTWKPQGAPVEWEE------ETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPD 796
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+ VT+YS ED P AP + NST + VTW+ + ++R+ G+L G+++ +WK ++
Sbjct: 797 PQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTV--PKDRVHGRLKGYQINWWKTKS 854
Query: 476 --------KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
KE + + + RN ++ L + +++ V+A+NS G GPESE Y+ +T
Sbjct: 855 LLDGRTHPKEVNILRFSGQ--RNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTP 912
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ--DMSTANDTI 585
P++ P + V D T + W + N L GY ++ ++ ++ ND
Sbjct: 913 EGVPEQ-PTFLKVIKVDKDTATLSWGLPKKLNGN--LTGYLLQYQIINDTYEIGELNDIN 969
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGR 619
+ K ++SN+ Y + A ++ G G+
Sbjct: 970 ITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1003
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/216 (25%), Positives = 85/216 (39%), Gaps = 17/216 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A N L + + ++ P + K P + Y S G N L C+ E P+PT W
Sbjct: 308 YRCTASNFLGTATHDFHV-IVEEPPRWTKKP-QSAVY-STGSNGILLCEAEGEPQPTIKW 364
Query: 62 KKDNIVIG----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+ + + AG F E + L + VY C A N +GT + + V+
Sbjct: 365 RVNGSPVDNHPFAGDVVFPRE---ISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV 421
Query: 118 -PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P K V FLHC P + W ++++ L + +
Sbjct: 422 RPLIQTKDGENYATVVGYSAFLHCEFFASP--EAVVSWQ----KVEEVKPLEGRRYHIYE 475
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G L I + D G Y C V++AIG+ + L I
Sbjct: 476 NGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDI 511
Score = 56.0 bits (129), Expect = 4e-07
Identities = 57/237 (24%), Positives = 95/237 (40%), Gaps = 15/237 (6%)
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAEDM-PQVAPQLVSARSFNSTALNVTWNPIDQS 455
+ Y +V A N++G S+ + P PQ + ++ + + W P+ +S
Sbjct: 679 FVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPL-KS 737
Query: 456 RERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSA 513
E+ G + +R+ WK + E + T N L V + P Y Y VKV A N
Sbjct: 738 MEQ-NGPGLEYRVT-WKPQGAPVE---WEEETVTNHTLRV-MTPAVYAPYDVKVQAINQL 791
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
G GP+ + + P P V + T ++V W V L GY++ W+
Sbjct: 792 GSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWK 851
Query: 574 ----LDQDMSTANDTIVPIE-HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
LD I+ + + ++ ++L VLAY++ G G S P I
Sbjct: 852 TKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYI 908
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 7/172 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P P W K + G + L I +S D+G Y C A
Sbjct: 254 KGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTAS 313
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N GT +IV PR+ +K P S L C A+ +P W NG
Sbjct: 314 NFLGTATHDFHVIVEEPPRWTKK-PQSAVYSTGSNGILLCEAEGEP--QPTIKWRVNGSP 370
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ D + + E++ N+ + Y+C + G I ++ + +
Sbjct: 371 V----DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDV 418
Score = 44.0 bits (99), Expect = 0.002
Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 38/239 (15%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKH---PLELETYGSEGGNVTLKCKP-EAAPKP 57
Y+C A N+L + S ++ P F K PLE+E EG + L C P + P
Sbjct: 107 YRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVE----EGDPIVLPCNPPKGLPPL 162
Query: 58 TFTWKKDNIV-IGAGGKRFITENGNLIIRQLS-RDDEGVYTCVA----------KNQYGT 105
W + I + ++++ G+L + +D Y C A K
Sbjct: 163 HIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKL 222
Query: 106 DESRGRLIVLRAPRFLEKLPPR-------ITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+ I R P+ L LPP IT ++ L C A+ P WN G
Sbjct: 223 TVNSSNSIKQRKPKLL--LPPTESGSESSITILKGEILLLECFAEGLPTPQVD--WNKIG 278
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DL + K + G+ L I NVS D G+Y C + +G + + +E PP
Sbjct: 279 ------GDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPP 331
Score = 41.5 bits (93), Expect = 0.009
Identities = 45/170 (26%), Positives = 70/170 (41%), Gaps = 15/170 (8%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDD----EGVYTCVAKNQ 102
++C+ + P+PTF+W KD R I N + R + +G Y C A N+
Sbjct: 55 IECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNK 114
Query: 103 YGTDESRG-RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G S IV P+F EK+ P + + + L CN Y N
Sbjct: 115 LGIAMSEEIEFIVPSVPKFPKEKIDP-LEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEH 173
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVKSAIGRISSHVQ 209
I+ +Y++++ G+L NV D DY C +A R+ + VQ
Sbjct: 174 IEQDERVYMSQK-----GDLYFANVEEKDSRNDYCCF--AAFPRLRTIVQ 216
>AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion
molecule protein.
Length = 1224
Score = 255 bits (625), Expect = 3e-67
Identities = 180/634 (28%), Positives = 302/634 (47%), Gaps = 43/634 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
+YQCEA N ++A + V+ ++P + + E Y + G + L C+ A+P+
Sbjct: 414 VYQCEASNVHGTILANANIDVVDVRPLIQTK--DGENYATVVGYSAFLHCEFFASPEAVV 471
Query: 60 TWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+K V G+R+ I ENG L I + + +D G Y+C +N G L + A
Sbjct: 472 SWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNAT 531
Query: 119 RF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYL--WNHNGLRIKDSSDLYVNKRIKI 175
+ + PRI ++ LHC + D L + W+ +G + + + RI I
Sbjct: 532 KLRVSPKNPRIPKL--HMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGT--EDGRIII 587
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLE 235
DG LTI NV+L D G Y C +A+ + Q+ + P PP + + Q SV L
Sbjct: 588 DGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLT 647
Query: 236 WTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
W + I+ Y++ + E E+ R G+K TV L P+ Y
Sbjct: 648 WEAGADHNSNISEYIVEFEGN--------KEEPGRWEELTRVQGKK-TTVILPLAPFVRY 698
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ A+N +G QPS PS T P P N+ + ++ I W PL + QNG
Sbjct: 699 QFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNG 758
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
PG+ Y++ W+ G+ VE++ + + + + + Y PYDVKVQA N +G GP+
Sbjct: 759 PGLEYRVTWKPQGAPVEWEE------ETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPD 812
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+ VT+YS ED P AP + NST + VTW+ + ++R+ G+L G+++ +WK ++
Sbjct: 813 PQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTV--PKDRVHGRLKGYQINWWKTKS 870
Query: 476 --------KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
KE + + + RN ++ L + +++ V+A+NS G GPESE Y+ +T
Sbjct: 871 LLDGRTHPKEVNILRFSGQ--RNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTP 928
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ--DMSTANDTI 585
P++ P + V D T + W + N L GY ++ ++ ++ ND
Sbjct: 929 EGVPEQ-PTFLKVIKVDKDTATLSWGLPKKLNGN--LTGYLLQYQIINDTYEIGELNDIN 985
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGR 619
+ K ++SN+ Y + A ++ G G+
Sbjct: 986 ITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1019
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/216 (25%), Positives = 85/216 (39%), Gaps = 17/216 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A N L + + ++ P + K P + Y S G N L C+ E P+PT W
Sbjct: 324 YRCTASNFLGTATHDFHV-IVEEPPRWTKKP-QSAVY-STGSNGILLCEAEGEPQPTIKW 380
Query: 62 KKDNIVIG----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+ + + AG F E + L + VY C A N +GT + + V+
Sbjct: 381 RVNGSPVDNHPFAGDVVFPRE---ISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV 437
Query: 118 -PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P K V FLHC P + W ++++ L + +
Sbjct: 438 RPLIQTKDGENYATVVGYSAFLHCEFFASP--EAVVSWQ----KVEEVKPLEGRRYHIYE 491
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G L I + D G Y C V++AIG+ + L I
Sbjct: 492 NGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDI 527
Score = 56.0 bits (129), Expect = 4e-07
Identities = 57/237 (24%), Positives = 95/237 (40%), Gaps = 15/237 (6%)
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAEDM-PQVAPQLVSARSFNSTALNVTWNPIDQS 455
+ Y +V A N++G S+ + P PQ + ++ + + W P+ +S
Sbjct: 695 FVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPL-KS 753
Query: 456 RERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSA 513
E+ G + +R+ WK + E + T N L V + P Y Y VKV A N
Sbjct: 754 MEQ-NGPGLEYRVT-WKPQGAPVE---WEEETVTNHTLRV-MTPAVYAPYDVKVQAINQL 807
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
G GP+ + + P P V + T ++V W V L GY++ W+
Sbjct: 808 GSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWK 867
Query: 574 ----LDQDMSTANDTIVPIE-HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
LD I+ + + ++ ++L VLAY++ G G S P I
Sbjct: 868 TKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYI 924
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 7/172 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P P W K + G + L I +S D+G Y C A
Sbjct: 270 KGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTAS 329
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N GT +IV PR+ +K P S L C A+ +P W NG
Sbjct: 330 NFLGTATHDFHVIVEEPPRWTKK-PQSAVYSTGSNGILLCEAEGEP--QPTIKWRVNGSP 386
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ D + + E++ N+ + Y+C + G I ++ + +
Sbjct: 387 V----DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDV 434
Score = 41.5 bits (93), Expect = 0.009
Identities = 45/170 (26%), Positives = 70/170 (41%), Gaps = 15/170 (8%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDD----EGVYTCVAKNQ 102
++C+ + P+PTF+W KD R I N + R + +G Y C A N+
Sbjct: 55 IECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNK 114
Query: 103 YGTDESRG-RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G S IV P+F EK+ P + + + L CN Y N
Sbjct: 115 LGIAMSEEIEFIVPSVPKFPKEKIDP-LEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEH 173
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVKSAIGRISSHVQ 209
I+ +Y++++ G+L NV D DY C +A R+ + VQ
Sbjct: 174 IEQDERVYMSQK-----GDLYFANVEEKDSRNDYCCF--AAFPRLRTIVQ 216
Score = 33.9 bits (74), Expect = 1.9
Identities = 62/255 (24%), Positives = 95/255 (37%), Gaps = 54/255 (21%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKH---PLELETYGSEGGNVTLKCKP-EAAPKP 57
Y+C A N+L + S ++ P F K PLE+E EG + L C P + P
Sbjct: 107 YRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVE----EGDPIVLPCNPPKGLPPL 162
Query: 58 TFTWKKDNIV-IGAGGKRFITENGNLIIRQLS-RDDEGVYTC------------------ 97
W + I + ++++ G+L + +D Y C
Sbjct: 163 HIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKL 222
Query: 98 -VAKNQYGTDES-------RGRLIVLRAPRFLEKLPPR-------ITAQVNSVVFLHCNA 142
V ++ D S + I R P+ L LPP IT ++ L C A
Sbjct: 223 TVNSLKHANDSSSSTEIGSKANSIKQRKPKLL--LPPTESGSESSITILKGEILLLECFA 280
Query: 143 DVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAI 201
+ P WN G DL + K + G+ L I NVS D G+Y C + +
Sbjct: 281 EGLPTPQVD--WNKIG------GDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFL 332
Query: 202 GRISSHVQLRIEGPP 216
G + + +E PP
Sbjct: 333 GTATHDFHVIVEEPP 347
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 255 bits (625), Expect = 3e-67
Identities = 180/634 (28%), Positives = 302/634 (47%), Gaps = 43/634 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
+YQCEA N ++A + V+ ++P + + E Y + G + L C+ A+P+
Sbjct: 400 VYQCEASNVHGTILANANIDVVDVRPLIQTK--DGENYATVVGYSAFLHCEFFASPEAVV 457
Query: 60 TWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+K V G+R+ I ENG L I + + +D G Y+C +N G L + A
Sbjct: 458 SWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNAT 517
Query: 119 RF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYL--WNHNGLRIKDSSDLYVNKRIKI 175
+ + PRI ++ LHC + D L + W+ +G + + + RI I
Sbjct: 518 KLRVSPKNPRIPKL--HMLELHCESKCDSHLKHSLKLSWSKDGEAFEINGT--EDGRIII 573
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLE 235
DG LTI NV+L D G Y C +A+ + Q+ + P PP + + Q SV L
Sbjct: 574 DGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVPDPPENLHLSERQNRSVRLT 633
Query: 236 WTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
W + I+ Y++ + E E+ R G+K TV L P+ Y
Sbjct: 634 WEAGADHNSNISEYIVEFEGN--------KEEPGRWEELTRVQGKK-TTVILPLAPFVRY 684
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ A+N +G QPS PS T P P N+ + ++ I W PL + QNG
Sbjct: 685 QFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPLKSMEQNG 744
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
PG+ Y++ W+ G+ VE++ + + + + + Y PYDVKVQA N +G GP+
Sbjct: 745 PGLEYRVTWKPQGAPVEWEE------ETVTNHTLRVMTPAVYAPYDVKVQAINQLGSGPD 798
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+ VT+YS ED P AP + NST + VTW+ + ++R+ G+L G+++ +WK ++
Sbjct: 799 PQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTV--PKDRVHGRLKGYQINWWKTKS 856
Query: 476 --------KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
KE + + + RN ++ L + +++ V+A+NS G GPESE Y+ +T
Sbjct: 857 LLDGRTHPKEVNILRFSGQ--RNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYIFQTP 914
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ--DMSTANDTI 585
P++ P + V D T + W + N L GY ++ ++ ++ ND
Sbjct: 915 EGVPEQ-PTFLKVIKVDKDTATLSWGLPKKLNGN--LTGYLLQYQIINDTYEIGELNDIN 971
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGR 619
+ K ++SN+ Y + A ++ G G+
Sbjct: 972 ITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGK 1005
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/216 (25%), Positives = 85/216 (39%), Gaps = 17/216 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A N L + + ++ P + K P + Y S G N L C+ E P+PT W
Sbjct: 310 YRCTASNFLGTATHDFHV-IVEEPPRWTKKP-QSAVY-STGSNGILLCEAEGEPQPTIKW 366
Query: 62 KKDNIVIG----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+ + + AG F E + L + VY C A N +GT + + V+
Sbjct: 367 RVNGSPVDNHPFAGDVVFPRE---ISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV 423
Query: 118 -PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P K V FLHC P + W ++++ L + +
Sbjct: 424 RPLIQTKDGENYATVVGYSAFLHCEFFASP--EAVVSWQ----KVEEVKPLEGRRYHIYE 477
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G L I + D G Y C V++AIG+ + L I
Sbjct: 478 NGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDI 513
Score = 56.0 bits (129), Expect = 4e-07
Identities = 57/237 (24%), Positives = 95/237 (40%), Gaps = 15/237 (6%)
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAEDM-PQVAPQLVSARSFNSTALNVTWNPIDQS 455
+ Y +V A N++G S+ + P PQ + ++ + + W P+ +S
Sbjct: 681 FVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKWEPL-KS 739
Query: 456 RERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSA 513
E+ G + +R+ WK + E + T N L V + P Y Y VKV A N
Sbjct: 740 MEQ-NGPGLEYRVT-WKPQGAPVE---WEEETVTNHTLRV-MTPAVYAPYDVKVQAINQL 793
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
G GP+ + + P P V + T ++V W V L GY++ W+
Sbjct: 794 GSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQINWWK 853
Query: 574 ----LDQDMSTANDTIVPIE-HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
LD I+ + + ++ ++L VLAY++ G G S P I
Sbjct: 854 TKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEPYI 910
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 7/172 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P P W K + G + L I +S D+G Y C A
Sbjct: 256 KGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTAS 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N GT +IV PR+ +K P S L C A+ +P W NG
Sbjct: 316 NFLGTATHDFHVIVEEPPRWTKK-PQSAVYSTGSNGILLCEAEGEP--QPTIKWRVNGSP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ D + + E++ N+ + Y+C + G I ++ + +
Sbjct: 373 V----DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDV 420
Score = 44.0 bits (99), Expect = 0.002
Identities = 61/239 (25%), Positives = 92/239 (38%), Gaps = 38/239 (15%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKH---PLELETYGSEGGNVTLKCKP-EAAPKP 57
Y+C A N+L + S ++ P F K PLE+E EG + L C P + P
Sbjct: 109 YRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVE----EGDPIVLPCNPPKGLPPL 164
Query: 58 TFTWKKDNIV-IGAGGKRFITENGNLIIRQLS-RDDEGVYTCVA----------KNQYGT 105
W + I + ++++ G+L + +D Y C A K
Sbjct: 165 HIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKL 224
Query: 106 DESRGRLIVLRAPRFLEKLPPR-------ITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+ I R P+ L LPP IT ++ L C A+ P WN G
Sbjct: 225 TVNSSNSIKQRKPKLL--LPPTESGSESSITILKGEILLLECFAEGLPTPQVD--WNKIG 280
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DL + K + G+ L I NVS D G+Y C + +G + + +E PP
Sbjct: 281 ------GDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPP 333
Score = 41.5 bits (93), Expect = 0.009
Identities = 45/170 (26%), Positives = 70/170 (41%), Gaps = 15/170 (8%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDD----EGVYTCVAKNQ 102
++C+ + P+PTF+W KD R I N + R + +G Y C A N+
Sbjct: 57 IECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNK 116
Query: 103 YGTDESRG-RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G S IV P+F EK+ P + + + L CN Y N
Sbjct: 117 LGIAMSEEIEFIVPSVPKFPKEKIDP-LEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEH 175
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVKSAIGRISSHVQ 209
I+ +Y++++ G+L NV D DY C +A R+ + VQ
Sbjct: 176 IEQDERVYMSQK-----GDLYFANVEEKDSRNDYCCF--AAFPRLRTIVQ 218
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 253 bits (619), Expect = 2e-66
Identities = 175/627 (27%), Positives = 282/627 (44%), Gaps = 37/627 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 423 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 481
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + + P
Sbjct: 482 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI-KDPT 540
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 541 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 594
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L + +VS D G Y CV + + +S+ L + P PP +++ SV L WT
Sbjct: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPG 654
Query: 240 NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRI 299
+ N PIT +++ Y + + P + + T L P+ Y FR+
Sbjct: 655 DDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRV 705
Query: 300 QAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIH 359
A+N +G PS S Q+ T +P + P V G G + +L ITW PL NGPG+
Sbjct: 706 MAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQ 765
Query: 360 YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND+G PE VV
Sbjct: 766 YKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALNDMGFAPEPAVV 820
Query: 420 TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEE 479
+S ED+P VAP V NST V W+P+ + +RG L G+R+ YWK ++ +
Sbjct: 821 MGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIYYWKTQSSSKR 878
Query: 480 CIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQK 533
++ + ++ ++ GL+P ++Y + V N GEGP S +R F
Sbjct: 879 NRRHIEKKILTFQGSKTHGMLPGLEPLSHYTLNVRVVNGKGEGPASP---DRVFNTPEGV 935
Query: 534 PPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTANDTIVPIEHK 591
P A ++ +PT + + P++ L Y ++ ++ ++ D +P +K
Sbjct: 936 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDLKIP-TNK 994
Query: 592 LEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ N+ Y A ++ G G
Sbjct: 995 TRWTLKNLNFSTRYKFYFYAQTSAGSG 1021
Score = 79.0 bits (186), Expect = 5e-14
Identities = 137/632 (21%), Positives = 226/632 (35%), Gaps = 51/632 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 332 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 388
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R L N L C P+ + G + + D+YV + G
Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLH----ENG 502
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I G Y CV ++ +G + V L I+ P + +QR S V+ E
Sbjct: 503 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 562
Query: 238 DSNSNGRPITG-YMLTGRTHWNSTWYVISENIPNVMEV-DRYNGRKRATVSTTLLPWAIY 295
+ + +T ++ R + + + ++ V +V D +G +TTL
Sbjct: 563 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL------ 616
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+ A +L P+P F + +S G + IT ++
Sbjct: 617 -DSVSASAVL--SVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPIT----KFIIEYE 669
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
+H W +EV G T + +S Y+ + V + P
Sbjct: 670 DAMHKPGLWHHQ-TEVS---------GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEA 719
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
SE ++E P P V L +TW P++ G + +++ W+Q++
Sbjct: 720 SEQYLTKASE--PDKNPTAVEGLGSEPDNLVITWKPLNGFES--NGPGLQYKVS-WRQKD 774
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPP 535
++E + + ++ G Y +KV A N G PE + + P P
Sbjct: 775 GDDEWTSVVVANVSKY-IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAP 833
Query: 536 ASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----DTIVPIE- 589
+V V + T V W V + L GY++ W+ Q S N I+ +
Sbjct: 834 GNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK-TQSSSKRNRRHIEKKILTFQG 892
Query: 590 HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
K + + P Y L V + G+G S
Sbjct: 893 SKTHGMLPGLEPLSHYTLNVRVVNGKGEGPAS 924
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 338
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 339 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 395
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 396 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 447
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 57 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 116
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 117 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 174
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 175 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 215
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 114 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 172
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 173 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 215
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 248 bits (608), Expect = 4e-65
Identities = 170/581 (29%), Positives = 279/581 (48%), Gaps = 43/581 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 399 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 454
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 455 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 513
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 514 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 567
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW 236
LTI+ V+ D G Y CV + + + + L + G P P +++ + SV L W
Sbjct: 568 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW 627
Query: 237 TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGRKRATVSTTLLPWAIY 295
++N PIT Y++ + + P V + +Y G + V L P+ Y
Sbjct: 628 IPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGSVNSAV-LRLSPYVNY 677
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ AIN +G PS PS ++ TSG P P +V G G + ++ ITWTP+ + G
Sbjct: 678 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 737
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y + WRR + + ++ + +G+ YVV T Y PY+++VQA ND G GPE
Sbjct: 738 PNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPYEIRVQAENDFGKGPE 791
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
E V YS ED P+ AP V R NSTA+++ WN + + ++G+L +R YW++ +
Sbjct: 792 PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQGQLREYRAYYWRESS 849
Query: 476 KEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ R ++ ++ L P + Y ++++ N G+GP SE E T +
Sbjct: 850 LLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSET-KEFTTPE 908
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
P V + T+ + W + P + ++GY ++
Sbjct: 909 GVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 947
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 625 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 679
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 680 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 733
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 734 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 793
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 794 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 853
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 854 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 899
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 168
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 169 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 228
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 229 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 280
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 281 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 331
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 255 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 314
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 315 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 371
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 372 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 424
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 52 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 111
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 112 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 169
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 170 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 207
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 248 bits (608), Expect = 4e-65
Identities = 170/581 (29%), Positives = 279/581 (48%), Gaps = 43/581 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 416 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 471
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 472 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 530
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 531 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 584
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW 236
LTI+ V+ D G Y CV + + + + L + G P P +++ + SV L W
Sbjct: 585 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW 644
Query: 237 TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGRKRATVSTTLLPWAIY 295
++N PIT Y++ + + P V + +Y G + V L P+ Y
Sbjct: 645 IPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGSVNSAV-LRLSPYVNY 694
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ AIN +G PS PS ++ TSG P P +V G G + ++ ITWTP+ + G
Sbjct: 695 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 754
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y + WRR + + ++ + +G+ YVV T Y PY+++VQA ND G GPE
Sbjct: 755 PNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPYEIRVQAENDFGKGPE 808
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
E V YS ED P+ AP V R NSTA+++ WN + + ++G+L +R YW++ +
Sbjct: 809 PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQGQLREYRAYYWRESS 866
Query: 476 KEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ R ++ ++ L P + Y ++++ N G+GP SE E T +
Sbjct: 867 LLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSET-KEFTTPE 925
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
P V + T+ + W + P + ++GY ++
Sbjct: 926 GVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 964
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 642 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 696
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 697 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 750
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 751 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 810
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 811 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 870
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 871 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 916
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 272 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 331
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 332 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 388
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 389 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 441
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 52 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 111
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 112 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 169
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 170 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 207
Score = 37.9 bits (84), Expect = 0.12
Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 40/247 (16%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 168
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAK------------------ 100
W ++ KR NG+L + +D + Y+C A+
Sbjct: 169 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 228
Query: 101 --NQYGTDESRGRLIVLRAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILD 149
+ Y R + A E+ P P+ TA V + L C A P D
Sbjct: 229 TNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPD 288
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ 209
A+ L + NK ++I NVS D G+Y C+ + +G I +
Sbjct: 289 IAWYKKGGDLPSDKAKFENFNKALRIT-------NVSEEDSGEYFCLASNKMGSIRHTIS 341
Query: 210 LRIEGPP 216
+R++ P
Sbjct: 342 VRVKAAP 348
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 248 bits (608), Expect = 4e-65
Identities = 170/581 (29%), Positives = 279/581 (48%), Gaps = 43/581 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 213 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 268
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 269 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 327
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 328 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 381
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW 236
LTI+ V+ D G Y CV + + + + L + G P P +++ + SV L W
Sbjct: 382 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW 441
Query: 237 TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGRKRATVSTTLLPWAIY 295
++N PIT Y++ + + P V + +Y G + V L P+ Y
Sbjct: 442 IPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGSVNSAV-LRLSPYVNY 491
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ AIN +G PS PS ++ TSG P P +V G G + ++ ITWTP+ + G
Sbjct: 492 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 551
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y + WRR + + ++ + +G+ YVV T Y PY+++VQA ND G GPE
Sbjct: 552 PNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPYEIRVQAENDFGKGPE 605
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
E V YS ED P+ AP V R NSTA+++ WN + + ++G+L +R YW++ +
Sbjct: 606 PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQGQLREYRAYYWRESS 663
Query: 476 KEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ R ++ ++ L P + Y ++++ N G+GP SE E T +
Sbjct: 664 LLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSET-KEFTTPE 722
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
P V + T+ + W + P + ++GY ++
Sbjct: 723 GVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 761
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 439 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 493
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 494 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 547
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 548 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 607
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 608 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 667
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 668 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 713
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 69 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 128
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 129 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 185
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 186 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 238
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 248 bits (608), Expect = 4e-65
Identities = 170/581 (29%), Positives = 279/581 (48%), Gaps = 43/581 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 469 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 524
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 525 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 583
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 584 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 637
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW 236
LTI+ V+ D G Y CV + + + + L + G P P +++ + SV L W
Sbjct: 638 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW 697
Query: 237 TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGRKRATVSTTLLPWAIY 295
++N PIT Y++ + + P V + +Y G + V L P+ Y
Sbjct: 698 IPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGSVNSAV-LRLSPYVNY 747
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+FR+ AIN +G PS PS ++ TSG P P +V G G + ++ ITWTP+ + G
Sbjct: 748 QFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFG 807
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y + WRR + + ++ + +G+ YVV T Y PY+++VQA ND G GPE
Sbjct: 808 PNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPYEIRVQAENDFGKGPE 861
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
E V YS ED P+ AP V R NSTA+++ WN + + ++G+L +R YW++ +
Sbjct: 862 PESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQGQLREYRAYYWRESS 919
Query: 476 KEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ R ++ ++ L P + Y ++++ N G+GP SE E T +
Sbjct: 920 LLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSET-KEFTTPE 978
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
P V + T+ + W + P + ++GY ++
Sbjct: 979 GVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 1017
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 695 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 749
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 750 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 803
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 804 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 863
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 864 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 923
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 924 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 969
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 325 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 384
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 385 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 441
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 442 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 494
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 105 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 164
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 165 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 222
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 223 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 260
Score = 37.9 bits (84), Expect = 0.12
Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 40/247 (16%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 163 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 221
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAK------------------ 100
W ++ KR NG+L + +D + Y+C A+
Sbjct: 222 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 281
Query: 101 --NQYGTDESRGRLIVLRAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILD 149
+ Y R + A E+ P P+ TA V + L C A P D
Sbjct: 282 TNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPD 341
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ 209
A+ L + NK ++I NVS D G+Y C+ + +G I +
Sbjct: 342 IAWYKKGGDLPSDKAKFENFNKALRIT-------NVSEEDSGEYFCLASNKMGSIRHTIS 394
Query: 210 LRIEGPP 216
+R++ P
Sbjct: 395 VRVKAAP 401
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus protein.
Length = 1236
Score = 246 bits (601), Expect = 3e-64
Identities = 176/637 (27%), Positives = 283/637 (44%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 429 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 487
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + + P
Sbjct: 488 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI-KDPT 546
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 547 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 600
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT +++ Y + + P + + T L
Sbjct: 661 KSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKL 711
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 712 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 771
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 772 GFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 826
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 827 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 884
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 885 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 941
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P A ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 942 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 1001
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 1002 VDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
Score = 91.9 bits (218), Expect = 7e-18
Identities = 142/633 (22%), Positives = 232/633 (36%), Gaps = 43/633 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 338 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 394
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R L N L C P+ + G + + D+YV + G
Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLH----ENG 508
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I G Y CV ++ +G + V L I+ P + +QR S V+ E
Sbjct: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568
Query: 238 DSNSNGRPITG-YMLTGRTHWNSTWYVISENIPNVMEV-DRYNGRKRATVSTTLLPWAIY 295
+ + +T ++ R + + + ++ V +V D +G +TTL
Sbjct: 569 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL------ 622
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+ A +L AP+P + D P P ++ + ++WTP + N
Sbjct: 623 -DSVSASAVL---SVVAPTPTPAPVYDVP-NPPFDLELTDQLDKSVQLSWTPGDDN--NS 675
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + I + + + G T + +S Y Y +V A N IG
Sbjct: 676 PITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP---YVNYSFRVMAVNSIGKSLP 732
Query: 416 SEVVTIY-SAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE Y + P P V L +TW P++ G + +++ W+Q+
Sbjct: 733 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES--NGPGLQYKVS-WRQK 789
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ ++E + + ++ G Y +KV A N G PE + + P
Sbjct: 790 DGDDEWTSVVVANVSKY-IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVA 848
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----DTIVPIE 589
P +V V + T V W V + L GY++ W+ Q S N I+ +
Sbjct: 849 PGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK-TQSSSKRNRRHIEKKILTFQ 907
Query: 590 -HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
K + + P Y L V + G+G S
Sbjct: 908 GSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPAS 940
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 344
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 345 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 401
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 402 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 453
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 63 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 123 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 180
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 181 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 221
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 120 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 178
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 179 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 246 bits (601), Expect = 3e-64
Identities = 176/637 (27%), Positives = 283/637 (44%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 429 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 487
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + + P
Sbjct: 488 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI-KDPT 546
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 547 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 600
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 601 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 660
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT +++ Y + + P + + T L
Sbjct: 661 KSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKL 711
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 712 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 771
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 772 GFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 826
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 827 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 884
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 885 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 941
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P A ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 942 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 1001
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 1002 VDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
Score = 91.9 bits (218), Expect = 7e-18
Identities = 142/633 (22%), Positives = 232/633 (36%), Gaps = 43/633 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 338 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 394
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R L N L C P+ + G + + D+YV + G
Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLH----ENG 508
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I G Y CV ++ +G + V L I+ P + +QR S V+ E
Sbjct: 509 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 568
Query: 238 DSNSNGRPITG-YMLTGRTHWNSTWYVISENIPNVMEV-DRYNGRKRATVSTTLLPWAIY 295
+ + +T ++ R + + + ++ V +V D +G +TTL
Sbjct: 569 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL------ 622
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+ A +L AP+P + D P P ++ + ++WTP + N
Sbjct: 623 -DSVSASAVL---SVVAPTPTPAPVYDVP-NPPFDLELTDQLDKSVQLSWTPGDDN--NS 675
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + I + + + G T + +S Y Y +V A N IG
Sbjct: 676 PITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSP---YVNYSFRVMAVNSIGKSLP 732
Query: 416 SEVVTIY-SAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE Y + P P V L +TW P++ G + +++ W+Q+
Sbjct: 733 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFES--NGPGLQYKVS-WRQK 789
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ ++E + + ++ G Y +KV A N G PE + + P
Sbjct: 790 DGDDEWTSVVVANVSKY-IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVA 848
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----DTIVPIE 589
P +V V + T V W V + L GY++ W+ Q S N I+ +
Sbjct: 849 PGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK-TQSSSKRNRRHIEKKILTFQ 907
Query: 590 -HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
K + + P Y L V + G+G S
Sbjct: 908 GSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPAS 940
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 285 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 344
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 345 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 401
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 402 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 453
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 63 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 123 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 180
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 181 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 221
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 120 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 178
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 179 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 243 bits (595), Expect = 1e-63
Identities = 176/637 (27%), Positives = 282/637 (44%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 417 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 475
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + A
Sbjct: 476 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDAT- 534
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 535 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 588
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 589 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 648
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT +++ Y + + P + + T L
Sbjct: 649 KSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLNL 699
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 700 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 759
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 760 GFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 814
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 815 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 872
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 873 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 929
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P A ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 930 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 989
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 990 VDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1025
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 19 LRVLSLKPSFKKHPLELETYGSEG------GNV-TLKCKPEAAPKPTFTWKKDNIVIGAG 71
++V+S K S ++ P L G+ GNV +L+C E P P W K++ ++
Sbjct: 243 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN 302
Query: 72 GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ 131
+ L I +S D G Y C+AKN G + V AP ++ P +
Sbjct: 303 RTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWI-TAPQNLVLS 361
Query: 132 VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVG 191
L C A+ +P W NG+ I+ + D + KIDG + NV
Sbjct: 362 PGEDGTLICRANGNP--KPRISWLTNGVPIEIAPD---DPSRKIDGDTIIFSNVQERSSA 416
Query: 192 DYECVVKSAIGRISSHVQLRIEGPP 216
Y+C + G + ++ + + P
Sbjct: 417 VYQCNASNEYGYLLANAFVNVLAEP 441
Score = 53.6 bits (123), Expect = 2e-06
Identities = 61/231 (26%), Positives = 103/231 (44%), Gaps = 23/231 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 127 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 185
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK-NQYGTDESRGRLI--V 114
+ DN +++ NG+L L D Y C A+ N T + + + V
Sbjct: 186 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 245
Query: 115 LRAPRFLEKLPPRITAQVN---------SVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
+ A E+ P +T + N +V+ L C A+ P Y +G+ K+ +
Sbjct: 246 ISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP-TPIIYWAKEDGMLPKNRT 304
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+Y N L I +VS +D G+Y+C+ K+A+G I + +R++ P
Sbjct: 305 -VYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 349
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 70 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 129
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 130 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 187
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 188 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 228
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 243 bits (594), Expect = 2e-63
Identities = 176/637 (27%), Positives = 282/637 (44%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 410 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 468
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + A
Sbjct: 469 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDAT- 527
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 528 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 581
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 582 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 641
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT +++ Y + + P + + T L
Sbjct: 642 KSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKL 692
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 693 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 752
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 753 GFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 807
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 808 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 865
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 866 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 922
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P A ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 923 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 982
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 983 VDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1018
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 19 LRVLSLKPSFKKHPLELETYGSEG------GNV-TLKCKPEAAPKPTFTWKKDNIVIGAG 71
++V+S K S ++ P L G+ GNV +L+C E P P W K++ ++
Sbjct: 236 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN 295
Query: 72 GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ 131
+ L I +S D G Y C+AKN G + V AP ++ P +
Sbjct: 296 RTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWI-TAPQNLVLS 354
Query: 132 VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVG 191
L C A+ +P W NG+ I+ + D + KIDG + NV
Sbjct: 355 PGEDGTLICRANGNP--KPRISWLTNGVPIEIAPD---DPSRKIDGDTIIFSNVQERSSA 409
Query: 192 DYECVVKSAIGRISSHVQLRIEGPP 216
Y+C + G + ++ + + P
Sbjct: 410 VYQCNASNEYGYLLANAFVNVLAEP 434
Score = 53.6 bits (123), Expect = 2e-06
Identities = 61/231 (26%), Positives = 103/231 (44%), Gaps = 23/231 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 120 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 178
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK-NQYGTDESRGRLI--V 114
+ DN +++ NG+L L D Y C A+ N T + + + V
Sbjct: 179 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 238
Query: 115 LRAPRFLEKLPPRITAQVN---------SVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
+ A E+ P +T + N +V+ L C A+ P Y +G+ K+ +
Sbjct: 239 ISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP-TPIIYWAKEDGMLPKNRT 297
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+Y N L I +VS +D G+Y+C+ K+A+G I + +R++ P
Sbjct: 298 -VYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 342
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 63 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 123 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 180
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 181 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 221
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 243 bits (594), Expect = 2e-63
Identities = 176/637 (27%), Positives = 282/637 (44%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 410 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 468
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + A
Sbjct: 469 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDAT- 527
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 528 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 581
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 582 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLD 641
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT +++ Y + + P + + T L
Sbjct: 642 KSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKL 692
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 693 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 752
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 753 GFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 807
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 808 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 865
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 866 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 922
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P A ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 923 DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINSTHELGPL 982
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 983 VDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1018
Score = 54.4 bits (125), Expect = 1e-06
Identities = 51/205 (24%), Positives = 84/205 (40%), Gaps = 13/205 (6%)
Query: 19 LRVLSLKPSFKKHPLELETYGSEG------GNV-TLKCKPEAAPKPTFTWKKDNIVIGAG 71
++V+S K S ++ P L G+ GNV +L+C E P P W K++ ++
Sbjct: 236 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKN 295
Query: 72 GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ 131
+ L I +S D G Y C+AKN G + V AP ++ P +
Sbjct: 296 RTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWI-TAPQNLVLS 354
Query: 132 VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVG 191
L C A+ +P W NG+ I+ + D + KIDG + NV
Sbjct: 355 PGEDGTLICRANGNP--KPRISWLTNGVPIEIAPD---DPSRKIDGDTIIFSNVQERSSA 409
Query: 192 DYECVVKSAIGRISSHVQLRIEGPP 216
Y+C + G + ++ + + P
Sbjct: 410 VYQCNASNEYGYLLANAFVNVLAEP 434
Score = 53.6 bits (123), Expect = 2e-06
Identities = 61/231 (26%), Positives = 103/231 (44%), Gaps = 23/231 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 120 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 178
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK-NQYGTDESRGRLI--V 114
+ DN +++ NG+L L D Y C A+ N T + + + V
Sbjct: 179 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKV 238
Query: 115 LRAPRFLEKLPPRITAQVN---------SVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
+ A E+ P +T + N +V+ L C A+ P Y +G+ K+ +
Sbjct: 239 ISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP-TPIIYWAKEDGMLPKNRT 297
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+Y N L I +VS +D G+Y+C+ K+A+G I + +R++ P
Sbjct: 298 -VYKNFE-----KTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAP 342
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 63 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 122
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 123 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 180
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 181 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 221
>X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1
protein.
Length = 824
Score = 242 bits (593), Expect = 2e-63
Identities = 172/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 51 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 108
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 109 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 168
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 169 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 224
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 225 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 284
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 285 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 333
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 334 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 393
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 394 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 447
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 448 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 505
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 506 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 564
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L V W+ P + L GY + LD+
Sbjct: 565 VPGHPEA-LHLECQSNTSLLVRWQ--PPLSHNGVLTGYVLSYHPLDE 608
Score = 89.8 bits (213), Expect = 3e-17
Identities = 139/617 (22%), Positives = 242/617 (39%), Gaps = 56/617 (9%)
Query: 49 CKPEAAPKPTFTWKKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
C+ + P+P TW+ + I + A +++ + G LI+ + D V C A+N++G
Sbjct: 2 CQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 61
Query: 107 ESRGRLIVLRAP-RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
+ + V++ P + L A S +L C A P+ +L + +G +
Sbjct: 62 LANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDE 120
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGG 221
+ G L I ++ +D G Y C+ + ++ L+++ GP
Sbjct: 121 RFF-----PYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRST 175
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYN 278
++ G R + T + + S IT + GR +S Y I + + +D +
Sbjct: 176 IEKKG-SRVTFTCQASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSD 233
Query: 279 GRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKT 338
+ V++T L + E R Q + + PG P P+ S D + V
Sbjct: 234 QGNYSCVASTELD--VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR------ 280
Query: 339 GDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
++W+P N P Y I + E L K GN + + +S Y
Sbjct: 281 ----VSWSPAED--HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YV 331
Query: 399 PYDVKVQAFNDIGPGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
Y +V A N GPG S V T+ + E P+ P V +T + +TW P+
Sbjct: 332 HYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD- 390
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGE 515
+ +R++ W+ + + + + L+V T+ Y +KV A NS G+
Sbjct: 391 -WNAPQVQYRVQ-WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGK 444
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
GPE + + + PQ P + + + + V WR V + L GY V W
Sbjct: 445 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREG 504
Query: 576 QDMSTAN-----DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ D +V + +S + P SY+L V A++ G G S T + G
Sbjct: 505 SQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEG 564
Query: 631 -DYHSEAYGYYARGSTS 646
H EA + +TS
Sbjct: 565 VPGHPEALHLECQSNTS 581
Score = 34.7 bits (76), Expect = 1.1
Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ + W S+ +TGY+L+ ++ + E +
Sbjct: 563 EGVPGHPEALHLECQSNTSLLVRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 614
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 615 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 671
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 672 SATAGENYSV-VSWVP 686
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 241 bits (591), Expect = 4e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 398 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 455
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 456 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVTDATQI 515
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 516 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 571
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 572 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 631
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 632 PAEDHNAPIEKYDIEFEDKEMAPGKWYSLGK-VP---------GNQTST-TLKLSPYVHY 680
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 681 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 740
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 741 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 794
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 795 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 852
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 853 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 911
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 912 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 955
Score = 94.7 bits (225), Expect = 1e-18
Identities = 153/665 (23%), Positives = 263/665 (39%), Gaps = 61/665 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 305 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 361
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 362 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 421
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 422 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 475
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L++ GP ++ G R + T
Sbjct: 476 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVTDATQITQGPRSTIEKKG-SRVTFTC 534
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 535 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 593
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 594 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 635
Query: 352 LQNGPGIHYKI-FWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDI 410
N P Y I F + + ++ SL K GN + + +S Y Y +V A N
Sbjct: 636 -HNAPIEKYDIEFEDKEMAPGKWYSLG-KVPGNQTSTTLKLSP---YVHYTFRVTAINKY 690
Query: 411 GPGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
GPG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 691 GPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ 748
Query: 470 YWKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTF 527
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 749 -WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSG 803
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN----- 582
PQ P + + + + V WR V + L GY V W +
Sbjct: 804 EDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHK 863
Query: 583 DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYA 641
D +V + +S + P SY+L V A++ G G S T + G H EA
Sbjct: 864 DHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLEC 923
Query: 642 RGSTS 646
+ +TS
Sbjct: 924 QSNTS 928
Score = 56.8 bits (131), Expect = 2e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 251 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNHNKTLQLLKVGEEDDGEYRCLAE 310
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 311 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 367
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 368 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 416
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 47 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 106
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 107 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 166
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 167 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 204
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 910 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 961
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 962 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1018
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1019 SATAGENYSV-VSWVP 1033
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 403 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 460
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 461 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 520
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 521 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 576
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 685
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 746 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 799
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 800 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 857
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 916
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 917 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 960
Score = 97.9 bits (233), Expect = 1e-19
Identities = 152/664 (22%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 310 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 366
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 367 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 426
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 427 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 480
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 539
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 540 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 598
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 599 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 640
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 641 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 696
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 697 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 753
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 754 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 809
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 810 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 869
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 929
Query: 643 GSTS 646
+TS
Sbjct: 930 SNTS 933
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 373 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 52 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 111
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 112 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 171
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 172 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 209
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 915 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 966
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 967 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1023
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1024 SATAGENYSV-VSWVP 1038
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 403 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 460
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 461 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 520
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 521 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 576
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLVTQSQVRVSWS 636
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 685
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 746 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 799
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 800 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 857
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 916
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 917 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 960
Score = 99.5 bits (237), Expect = 3e-20
Identities = 153/664 (23%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ E P+P TW
Sbjct: 310 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVEGRPQPEVTW 366
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 367 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 426
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 427 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 480
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 539
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 540 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 598
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 599 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLVTQSQVR----------VSWSPAED- 640
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 641 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 696
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 697 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 753
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 754 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 809
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 810 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 869
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 929
Query: 643 GSTS 646
+TS
Sbjct: 930 SNTS 933
Score = 51.6 bits (118), Expect = 9e-06
Identities = 39/172 (22%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT + + + A + N L + ++ +D+G Y C+A+
Sbjct: 256 QGQPLVLECIAEGFPTPTIKSVRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C + P W NG+
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVEGRP--QPEVTWRINGIP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 373 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 52 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 111
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 112 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 171
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 172 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 209
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 915 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 966
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 967 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1023
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1024 SATAGENYSV-VSWVP 1038
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 403 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 460
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 461 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 520
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 521 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 576
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 685
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 746 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 799
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 800 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 857
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 916
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 917 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 960
Score = 97.9 bits (233), Expect = 1e-19
Identities = 152/664 (22%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 310 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 366
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 367 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 426
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 427 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 480
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 539
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 540 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 598
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 599 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 640
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 641 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 696
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 697 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 753
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 754 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 809
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 810 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 869
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 929
Query: 643 GSTS 646
+TS
Sbjct: 930 SNTS 933
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 373 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 52 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 111
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 112 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 171
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 172 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 209
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 915 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 966
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 967 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1023
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1024 SATAGENYSV-VSWVP 1038
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 403 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 460
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 461 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 520
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 521 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 576
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 685
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 746 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 799
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 800 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 857
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 916
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 917 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 960
Score = 97.9 bits (233), Expect = 1e-19
Identities = 152/664 (22%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 310 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 366
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 367 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 426
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 427 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 480
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 539
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 540 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 598
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 599 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 640
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 641 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 696
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 697 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 753
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 754 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 809
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 810 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 869
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 929
Query: 643 GSTS 646
+TS
Sbjct: 930 SNTS 933
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 373 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 52 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 111
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 112 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 171
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 172 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 209
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 915 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 966
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 967 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1023
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1024 SATAGENYSV-VSWVP 1038
>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 403 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 460
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 461 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 520
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 521 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 576
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 637 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 685
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 746 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 799
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 800 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 857
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 916
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 917 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 960
Score = 97.9 bits (233), Expect = 1e-19
Identities = 152/664 (22%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 310 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 366
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 367 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 426
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 427 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 480
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 539
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 540 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 598
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 599 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 640
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 641 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 696
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 697 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 753
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 754 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 809
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 810 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 869
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 929
Query: 643 GSTS 646
+TS
Sbjct: 930 SNTS 933
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 256 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 316 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 372
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 373 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 421
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 52 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 111
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 112 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 171
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 172 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 209
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 915 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 966
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 967 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1023
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1024 SATAGENYSV-VSWVP 1038
>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1255
Score = 241 bits (590), Expect = 6e-63
Identities = 171/587 (29%), Positives = 281/587 (47%), Gaps = 42/587 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 401 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 458
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 459 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 518
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 519 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 574
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 575 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 634
Query: 238 DSNSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 635 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 683
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ AIN GPG+PS S T P + P +V G G +T ++ ITW PL N
Sbjct: 684 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 743
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P + Y++ WR G+ +Q ++ ++V +S+T + PY++KVQA N G GPE
Sbjct: 744 PQVQYRVQWRPQGTRGPWQEQIVS-----DPFLV-VSNTSTFVPYEIKVQAVNSQGKGPE 797
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+V YS ED PQ P+L NS+A+ V W P+D + +++G L G+ + YW++ +
Sbjct: 798 PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLA--QVKGHLRGYNVTYWREGS 855
Query: 476 KEEECIYYLSR------TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + ++ + ++ GL+P + Y+++V AFN G GP SE + T
Sbjct: 856 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG 914
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P P A +++ T+L + W+ P + L GY + LD+
Sbjct: 915 VPGHPEA-LHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPLDE 958
Score = 97.9 bits (233), Expect = 1e-19
Identities = 152/664 (22%), Positives = 260/664 (39%), Gaps = 59/664 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N L S A + P + P + YG G L C+ + P+P TW
Sbjct: 308 YRCLAENSL-GSARHAYYVTVEAAPYWLHKP-QSHLYGP-GETARLDCQVQGRPQPEVTW 364
Query: 62 KKDNIVIG--AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP- 118
+ + I + A +++ + G LI+ + D V C A+N++G + + V++ P
Sbjct: 365 RINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPA 424
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ L A S +L C A P+ +L + +G + + G
Sbjct: 425 KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQDERFF-----PYANG 478
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPPGGVQILGIQRSSVTL 234
L I ++ +D G Y C+ + ++ L+++ GP ++ G R + T
Sbjct: 479 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG-SRVTFTC 537
Query: 235 EWTDSNSNGRPITGYMLTGRTHW---NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLP 291
+ + S IT + GR +S Y I + + +D + + V++T L
Sbjct: 538 QASFDPSLQPSIT-WRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELD 596
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
+ E R Q + + PG P P+ S D + V ++W+P
Sbjct: 597 --VVESRAQLLVVGSPG----PVPRLVLS-DLHLLTQSQVR----------VSWSPAED- 638
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
N P Y I + E L K GN + + +S Y Y +V A N G
Sbjct: 639 -HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP---YVHYTFRVTAINKYG 694
Query: 412 PGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
PG S V T+ + E P+ P V +T + +TW P+ + +R++
Sbjct: 695 PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD--WNAPQVQYRVQ- 751
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTY--YYVKVMAFNSAGEGPESERYLERTFR 528
W+ + + + + L+V T+ Y +KV A NS G+GPE + + +
Sbjct: 752 WRPQGTRGP---WQEQIVSDPFLVVS-NTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGE 807
Query: 529 KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----D 583
PQ P + + + + V WR V + L GY V W + D
Sbjct: 808 DYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD 867
Query: 584 TIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG-DYHSEAYGYYAR 642
+V + +S + P SY+L V A++ G G S T + G H EA +
Sbjct: 868 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQ 927
Query: 643 GSTS 646
+TS
Sbjct: 928 SNTS 931
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 254 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 313
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 314 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 370
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 371 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 419
Score = 41.1 bits (92), Expect = 0.012
Identities = 40/163 (24%), Positives = 66/163 (40%), Gaps = 16/163 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-----ENGNLII----RQLSRDDEGV 94
+++LKC+ P+ F W +D + + +T +G+ I ++ +G+
Sbjct: 50 DISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGI 109
Query: 95 YTCVAKNQYGTDESRG-RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C A N+ GT S RL+ AP++ ++ + + V L CN Y
Sbjct: 110 YRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW 169
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYEC 195
N L IK + + + G L NV SD DY C
Sbjct: 170 MNSKILHIKQDERVTMGQ-----NGNLYFANVLTSDNHSDYIC 207
Score = 35.9 bits (79), Expect = 0.47
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 13/136 (9%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P + + +S+ L W S+ +TGY+L+ ++ + E +
Sbjct: 913 EGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLS--------YHPLDEGGKGQL 964
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA-PSPQFSTSGDKPYEAPANV 331
+ + R T L P Y F++QA GPG+ + SG + N+
Sbjct: 965 SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF---GNI 1021
Query: 332 SGGGGKTGDLTITWTP 347
S G+ + ++W P
Sbjct: 1022 SATAGENYSV-VSWVP 1036
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 237 bits (579), Expect = 1e-61
Identities = 176/637 (27%), Positives = 280/637 (43%), Gaps = 47/637 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 424 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIQ 482
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + + P
Sbjct: 483 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEI-KDPT 541
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 542 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 595
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPPGGVQILGIQR 229
L + +VS D G Y CV + + +S+ L + P P PP +++
Sbjct: 596 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPLDLELTDQLD 655
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
SV L WT + N PIT H Y + + P + + T L
Sbjct: 656 KSVQLSWTPGDDNNSPIT------TIHDE---YEDAMHKPGLWHHQTEVSGTQTTAQLKL 706
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P+ Y FR+ A+N +G PS S Q+ T +P + P V G G + +L ITW PL
Sbjct: 707 SPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLN 766
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + PY +KVQA ND
Sbjct: 767 GFEFNGPGLQYKVSWRQKVGDDEWTSVVV---ANVSKYIV--SGTPTFVPYLIKVQALND 821
Query: 410 IGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLK 469
+G PE VV +S ED+P VAP V NST V W+P+ + +RG L G+R+
Sbjct: 822 MGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSIRGHLQGYRIY 879
Query: 470 YWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
YWK ++ + ++ + ++ ++ GL+P ++Y + V N GEGP S
Sbjct: 880 YWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASP--- 936
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD--QDMSTA 581
+R F P ++ +PT + + P++ L Y ++ ++ ++
Sbjct: 937 DRVFNTPEGVPSVPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQPINNTHELGPL 996
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D +P +K + N+ Y A ++ G G
Sbjct: 997 VDLKIP-ANKTRWTLKNLNFTTRYKFYFYAQTSAGSG 1032
Score = 87.4 bits (207), Expect = 1e-16
Identities = 141/633 (22%), Positives = 227/633 (35%), Gaps = 43/633 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 333 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 389
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 390 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 449
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R L N L C P+ + G + + D+YV + G
Sbjct: 450 RILTPANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHE--DIYVLH----ENG 503
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I G Y CV ++ +G + V L I+ P + +QR S V+ E
Sbjct: 504 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECK 563
Query: 238 DSNSNGRPITG-YMLTGRTHWNSTWYVISENIPNVMEV-DRYNGRKRATVSTTLLPWAIY 295
+ + +T ++ R + + + ++ V +V D +G +TTL
Sbjct: 564 VKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTL------ 617
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
+ A +L AP+P + D P P ++ + ++WTP +
Sbjct: 618 -DSVSASAVL---SVVAPTPTPAPVYDVP-NPPLDLELTDQLDKSVQLSWTPGDDNNSPI 672
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
IH + + L + GT Y Y +V A N IG
Sbjct: 673 TTIHDEY-----EDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 727
Query: 416 SEVVTIY-SAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE Y + P P V L +TW P++ G + +++ W+Q+
Sbjct: 728 SEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGF--EFNGPGLQYKVS-WRQK 784
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
++E + + ++ G Y +KV A N G PE + + P
Sbjct: 785 VGDDEWTSVVVANVSKY-IVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVA 843
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAN-----DTIVPIE 589
P +V V + T V W V + L GY++ W+ Q S N I+ +
Sbjct: 844 PGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWK-TQSSSKRNRRHIEKKILTFQ 902
Query: 590 -HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
K + + P Y L V + G+G S
Sbjct: 903 GSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPAS 935
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 280 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 339
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 340 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 396
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 397 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 448
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 58 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 117
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 118 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 176 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 216
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 115 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 173
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 174 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 216
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 234 bits (573), Expect = 6e-61
Identities = 170/596 (28%), Positives = 280/596 (46%), Gaps = 58/596 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 392 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 447
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 448 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 506
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 507 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 560
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---------------EGPPGPPGG 221
LTI+ V+ D G Y CV + + + + L + +G P P
Sbjct: 561 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 620
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGR 280
+++ + SV L W ++N PIT Y++ + + P V + +Y G
Sbjct: 621 LELTDLAERSVRLTWIPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGS 671
Query: 281 KRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGD 340
+ V L P+ Y+FR+ AIN +G PS PS ++ TSG P P +V G G + +
Sbjct: 672 VNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 730
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ ITWTP+ + GP + Y + WRR + + ++ + +G+ YVV T Y PY
Sbjct: 731 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPY 784
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+++VQA ND G GPE E V YS ED P+ AP V R NSTA+++ WN + + ++
Sbjct: 785 EIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQ 842
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAG 514
G+L +R YW++ + + R ++ ++ L P + Y ++++ N G
Sbjct: 843 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 902
Query: 515 EGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
+GP SE E T + P V + T+ + W + P + ++GY ++
Sbjct: 903 DGPRSET-KEFTTPEGVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 955
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 633 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 687
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 688 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 741
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 742 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 801
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 802 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 861
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 862 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 907
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 248 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 307
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 308 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 364
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 365 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 417
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 28 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 87
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 88 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 145
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 146 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 183
Score = 37.9 bits (84), Expect = 0.12
Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 40/247 (16%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 86 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 144
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAK------------------ 100
W ++ KR NG+L + +D + Y+C A+
Sbjct: 145 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 204
Query: 101 --NQYGTDESRGRLIVLRAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILD 149
+ Y R + A E+ P P+ TA V + L C A P D
Sbjct: 205 TNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPD 264
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ 209
A+ L + NK ++I NVS D G+Y C+ + +G I +
Sbjct: 265 IAWYKKGGDLPSDKAKFENFNKALRIT-------NVSEEDSGEYFCLASNKMGSIRHTIS 317
Query: 210 LRIEGPP 216
+R++ P
Sbjct: 318 VRVKAAP 324
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 234 bits (573), Expect = 6e-61
Identities = 170/596 (28%), Positives = 280/596 (46%), Gaps = 58/596 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 460
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 519
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 520 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 573
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---------------EGPPGPPGG 221
LTI+ V+ D G Y CV + + + + L + +G P P
Sbjct: 574 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 633
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGR 280
+++ + SV L W ++N PIT Y++ + + P V + +Y G
Sbjct: 634 LELTDLAERSVRLTWIPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGS 684
Query: 281 KRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGD 340
+ V L P+ Y+FR+ AIN +G PS PS ++ TSG P P +V G G + +
Sbjct: 685 VNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 743
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ ITWTP+ + GP + Y + WRR + + ++ + +G+ YVV T Y PY
Sbjct: 744 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPY 797
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+++VQA ND G GPE E V YS ED P+ AP V R NSTA+++ WN + + ++
Sbjct: 798 EIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRV--YSDTVQ 855
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNW------ALIVGLQPDTYYYVKVMAFNSAG 514
G+L +R YW++ + + R ++ ++ L P + Y ++++ N G
Sbjct: 856 GQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRG 915
Query: 515 EGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
+GP SE E T + P V + T+ + W + P + ++GY ++
Sbjct: 916 DGPRSET-KEFTTPEGVPSAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 968
Score = 60.5 bits (140), Expect = 2e-08
Identities = 61/286 (21%), Positives = 106/286 (37%), Gaps = 18/286 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 646 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 700
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 701 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 754
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 755 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 814
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM-- 578
+ + P+ P V V + T + + W V + L Y+ W +
Sbjct: 815 SVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKN 874
Query: 579 ---STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
S +L +S + P +Y L ++ + GDG S
Sbjct: 875 LWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRS 920
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 175 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 234
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 235 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 286
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 287 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 320
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 321 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 377
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 378 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 58 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 117
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 118 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 176 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 213
>BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein.
Length = 1805
Score = 232 bits (567), Expect = 3e-60
Identities = 179/637 (28%), Positives = 291/637 (45%), Gaps = 39/637 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
M+QC A+N +S L V S+ P+ + PL+ +G +V L C+ AP+P T
Sbjct: 10 MFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI--DGMSVVLACETSGAPRPAIT 67
Query: 61 WKKDNIVIGAGG---KRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W+K ++ +G RF E+G+L+I D G YTC+A N G DE+ L+V
Sbjct: 68 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 127
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
R + PP+ + + + C DP + Y+W +G + S + RI++
Sbjct: 128 RTRITK--PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTES----HPRIRL 181
Query: 176 D-GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG-PPGPPGGVQILG-IQRSSV 232
D G L I D+G Y C V SA G S LR+ P P V L ++R ++
Sbjct: 182 DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAI 241
Query: 233 TLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPW 292
L WT P+ Y+L + N+ W V+ ++ + + + L+P
Sbjct: 242 NLTWTKPFDGNSPLIRYILEMSEN-NAPWTVLLASV---------DPKATSVTVKGLVPA 291
Query: 293 AIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSL 352
Y+FR+ A+N +G GQ S + + S + P P NV G + I W P P S
Sbjct: 292 RSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESH 351
Query: 353 QNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
QNG Y I + G V +Q K + + + +T Y+++V A+N G
Sbjct: 352 QNGILKGYIIRYCLAGLPVGYQ---FKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGL 408
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWK 472
G S VT ++ + +P V P V A + NST + TWN S + + G G++L W+
Sbjct: 409 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA--PSPQFINGINQGYKLIAWE 466
Query: 473 QENKEEECIYYLS---RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
E +EE + + + + + GL+ T Y+ V+ F + G+GP S L RT
Sbjct: 467 PEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHED 526
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE 589
P P ++ T+L+V W+ +P + L GY++ WE +T +P
Sbjct: 527 VP-GPVGHLSFSEILDTSLKVSWQ--EPGEKNGILTGYRIS-WEEYNRTNTRVTHYLP-N 581
Query: 590 HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
LE ++ + +Y + V A ++ G G++S+ TI+
Sbjct: 582 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 618
Score = 127 bits (307), Expect = 1e-28
Identities = 111/418 (26%), Positives = 188/418 (44%), Gaps = 27/418 (6%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYML---TGRTHWNSTWYVISENIPNVM 272
PGPP + I I SVTL++ I+ +++ G W +I + + N
Sbjct: 626 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQ-LSN-- 682
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
E D R+ L P+ Y FR++ +NI+G PS PS + T P APANVS
Sbjct: 683 EPDA-----RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVS 737
Query: 333 GGGGKTGDLTITWTPLPTSLQNG--PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
L + W PLP NG + YKI + R+ + S +++ +
Sbjct: 738 LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIED 797
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ +T Y V+VQAFN IG GP S+ V + E +P P VSA + S+++ V W+
Sbjct: 798 LEE---WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 854
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
+ ++ G ++G+++ Y ++++ + + + + A + GL Y V+V+AF
Sbjct: 855 EVPEADR--NGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAF 912
Query: 511 NSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
G+G P LERT P PP + T++R++W+ P +L Y++
Sbjct: 913 TRIGDGSPSHPPILERTLDDVP-GPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQI 969
Query: 570 --RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
RL + +T + + P + A + + P Y R+ A + G G + +
Sbjct: 970 THRLNTTTANTATV-EVLAPSARQYTA--TGLKPESVYLFRITAQTRKGWGEAAEALV 1024
Score = 88.2 bits (209), Expect = 8e-17
Identities = 76/332 (22%), Positives = 140/332 (42%), Gaps = 13/332 (3%)
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
W Y ++QA N +G G P + + T P P NVS + + + W+ +P +
Sbjct: 801 WTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 859
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
+NG + YK+ ++ S+ + + L++ GN + ++ Y Y+V+V AF IG
Sbjct: 860 DRNGLVLGYKVMYKEKDSDTQPRFWLVE--GN-SSRSAQLTGLGKYVLYEVQVLAFTRIG 916
Query: 412 PG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
G P + + +D+P P + +T++ + W P + I HRL
Sbjct: 917 DGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 975
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKA 530
E L+ + R + GL+P++ Y ++ A G G +E + T ++
Sbjct: 976 TTANTATVEV---LAPSARQYTA-TGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD 1031
Query: 531 PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEH 590
+PP+ V D V+ + ++ P+ Y ++ EL + + H
Sbjct: 1032 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHS--ASVSH 1089
Query: 591 KLEAYI-SNIIPGKSYNLRVLAYSNGGDGRMS 621
++I + P SY RV A ++ GD S
Sbjct: 1090 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1121
Score = 88.2 bits (209), Expect = 8e-17
Identities = 89/336 (26%), Positives = 137/336 (40%), Gaps = 21/336 (6%)
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
YE R+ N +G G PS+P + P AP NV G L +TW P P QN
Sbjct: 1228 YEIRMSVYNAVGEG-PSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQN 1286
Query: 355 GPGIHYKI-FWR-RNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
G YKI FW + G+ E L + V + + YT Y V V AFN G
Sbjct: 1287 GDIQGYKIYFWEAQRGNLTERVKTLF-----LAENSVKLKNLTGYTAYMVSVAAFNAAGD 1341
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY-- 470
GP S + + P AP V +T++NV+W ++ + G L G+RL Y
Sbjct: 1342 GPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNVSW----EAPQFPNGILEGYRLVYEP 1396
Query: 471 -WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + + + W + L Y ++ A + GPE E + +
Sbjct: 1397 CSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGE 1455
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE 589
PP V + + + + W P + P+ Y + D+ + +P E
Sbjct: 1456 GAPGPP-GVPIIVRYSSAIAIHWSSGDP--GKGPITRYVIEARPSDEGLWDILIKDIPKE 1512
Query: 590 HKLEAYISNII-PGKSYNLRVLAYSNGGDGRMSSPT 624
+ +I+ PG SY+ RV+A ++ G G SSP+
Sbjct: 1513 VSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 1548
Score = 87.0 bits (206), Expect = 2e-16
Identities = 98/438 (22%), Positives = 177/438 (40%), Gaps = 44/438 (10%)
Query: 212 IEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
++ PGPP G+ ++ +SV L W + I Y +T R ++ N
Sbjct: 930 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR---------LNTTTANT 980
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN- 330
V+ R +T L P ++Y FRI A G G+ + + D+P + P+
Sbjct: 981 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP-QPPSRP 1039
Query: 331 -VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
V + + ++W P L P +Y I R S + N +++V
Sbjct: 1040 MVQQEDVRARSVLLSWEPGSDGL--SPVRYYTIQTRELPSG-RWALHSASVSHNASSFIV 1096
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+T Y +V+A NDIG S E ++ + + P AP ++S +T++ +
Sbjct: 1097 DRLKP--FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1154
Query: 449 WNPIDQSRERLRGKLIGHRLKYWK--QENKEEECIYYLSRTTRNWALIV----------- 495
W P + +++ G L+G R++Y + E + ++ WA +
Sbjct: 1155 WQP--PAEDKINGILLGFRIRYRELLYEGLRGFMLRGINNPGATWAELTSMYSMRNLSRP 1212
Query: 496 --------GLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTT 547
L Y +++ +N+ GEGP S P P +V V T
Sbjct: 1213 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1272
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEAYISNIIPGKSYN 606
L V W ++ + GYK+ WE + +++ T+ E+ ++ + N+ +Y
Sbjct: 1273 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK--LKNLTGYTAYM 1330
Query: 607 LRVLAYSNGGDGRMSSPT 624
+ V A++ GDG S+PT
Sbjct: 1331 VSVAAFNAAGDGPRSTPT 1348
Score = 61.7 bits (143), Expect = 8e-09
Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PGPPG V I+ S++ + W+ + PIT Y++ R W ++ ++IP
Sbjct: 1455 EGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPK-- 1511
Query: 273 EVDRYNGRKRATVSTTLL-PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
EV Y T S +L P Y+FR+ A+N G G PS+PS P+
Sbjct: 1512 EVSSY------TFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPF 1559
Score = 55.6 bits (128), Expect = 5e-07
Identities = 84/369 (22%), Positives = 142/369 (38%), Gaps = 32/369 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P P V L SS+ + W++ R G +L + + S+ P V
Sbjct: 832 PSSGPTNVSALATTSSSMLVRWSEVPEADR--NGLVLGYKVMYKEK---DSDTQPRFWLV 886
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
+ R+ T L + +YE ++ A +G G PS P T D P P +
Sbjct: 887 E--GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 943
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWR-----RNGSEVEFQSLLLKKYGNIGTYVV 389
+T + + W P + NG + Y+I R N + VE + ++Y G +
Sbjct: 944 EVRTTSVRLIWQP--PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG---L 998
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ-LVSARSFNSTALNVT 448
S Y + + Q G E+ VVT D PQ + +V + ++ ++
Sbjct: 999 KPESVYLFR---ITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQQEDVRARSVLLS 1054
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWA--LIVGLQPDTYYYVK 506
W P +R I R E + + + N + ++ L+P T Y +
Sbjct: 1055 WEPGSDGLSPVRYYTIQTR------ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFR 1108
Query: 507 VMAFNSAGEGPESERYLE-RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLL 565
V A N G+ SE T + AP + P ++V H T++ + W+ LL
Sbjct: 1109 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1168
Query: 566 GYKVRLWEL 574
G+++R EL
Sbjct: 1169 GFRIRYREL 1177
Score = 39.9 bits (89), Expect = 0.029
Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 3/113 (2%)
Query: 90 DDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILD 149
DD G++ C A+N G ++ L V + + P T V L C P
Sbjct: 6 DDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAP--R 63
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
A W G RI S + + + ++ G L I +SD G Y C+ ++ G
Sbjct: 64 PAITW-QKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRG 115
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 232 bits (567), Expect = 3e-60
Identities = 179/637 (28%), Positives = 291/637 (45%), Gaps = 39/637 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
M+QC A+N +S L V S+ P+ + PL+ +G +V L C+ AP+P T
Sbjct: 54 MFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI--DGMSVVLACETSGAPRPAIT 111
Query: 61 WKKDNIVIGAGG---KRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W+K ++ +G RF E+G+L+I D G YTC+A N G DE+ L+V
Sbjct: 112 WQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWA 171
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
R + PP+ + + + C DP + Y+W +G + S + RI++
Sbjct: 172 RTRITK--PPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTES----HPRIRL 225
Query: 176 D-GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG-PPGPPGGVQILG-IQRSSV 232
D G L I D+G Y C V SA G S LR+ P P V L ++R ++
Sbjct: 226 DRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAI 285
Query: 233 TLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPW 292
L WT P+ Y+L + N+ W V+ ++ + + + L+P
Sbjct: 286 NLTWTKPFDGNSPLIRYILEMSEN-NAPWTVLLASV---------DPKATSVTVKGLVPA 335
Query: 293 AIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSL 352
Y+FR+ A+N +G GQ S + + S + P P NV G + I W P P S
Sbjct: 336 RSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESH 395
Query: 353 QNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
QNG Y I + G V +Q K + + + +T Y+++V A+N G
Sbjct: 396 QNGILKGYIIRYCLAGLPVGYQ---FKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGL 452
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWK 472
G S VT ++ + +P V P V A + NST + TWN S + + G G++L W+
Sbjct: 453 GVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNA--PSPQFINGINQGYKLIAWE 510
Query: 473 QENKEEECIYYLS---RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
E +EE + + + + + GL+ T Y+ V+ F + G+GP S L RT
Sbjct: 511 PEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHED 570
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE 589
P P ++ T+L+V W+ +P + L GY++ WE +T +P
Sbjct: 571 VP-GPVGHLSFSEILDTSLKVSWQ--EPGEKNGILTGYRIS-WEEYNRTNTRVTHYLP-N 625
Query: 590 HKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
LE ++ + +Y + V A ++ G G++S+ TI+
Sbjct: 626 VTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 662
Score = 127 bits (307), Expect = 1e-28
Identities = 111/418 (26%), Positives = 188/418 (44%), Gaps = 27/418 (6%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYML---TGRTHWNSTWYVISENIPNVM 272
PGPP + I I SVTL++ I+ +++ G W +I + + N
Sbjct: 670 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQ-LSN-- 726
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
E D R+ L P+ Y FR++ +NI+G PS PS + T P APANVS
Sbjct: 727 EPDA-----RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVS 781
Query: 333 GGGGKTGDLTITWTPLPTSLQNG--PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
L + W PLP NG + YKI + R+ + S +++ +
Sbjct: 782 LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIED 841
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ +T Y V+VQAFN IG GP S+ V + E +P P VSA + S+++ V W+
Sbjct: 842 LEE---WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 898
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
+ ++ G ++G+++ Y ++++ + + + + A + GL Y V+V+AF
Sbjct: 899 EVPEADR--NGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAF 956
Query: 511 NSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
G+G P LERT P PP + T++R++W+ P +L Y++
Sbjct: 957 TRIGDGSPSHPPILERTLDDVP-GPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQI 1013
Query: 570 --RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
RL + +T + + P + A + + P Y R+ A + G G + +
Sbjct: 1014 THRLNTTTANTATV-EVLAPSARQYTA--TGLKPESVYLFRITAQTRKGWGEAAEALV 1068
Score = 97.9 bits (233), Expect = 1e-19
Identities = 92/365 (25%), Positives = 150/365 (41%), Gaps = 35/365 (9%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
PP P VQ ++ SV L W + P+ Y + R + W + S ++ +
Sbjct: 1079 PPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSH---- 1133
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
+ + L P+ Y+FR++A N +G + S S +T P EAP +S
Sbjct: 1134 -----NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVT 1188
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISST 394
T + I W P NG + ++I +R E + L+ N G ++S
Sbjct: 1189 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE-GLRGFTLRGINNPGATWAELTSM 1247
Query: 395 YF-------------------YTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLV 435
Y + Y++++ +N +G GP S ++ E +P AP+ V
Sbjct: 1248 YSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNV 1307
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWK-QENKEEECIYYLSRTTRNWALI 494
+T L+VTW P + G + G+++ +W+ Q E + L N +
Sbjct: 1308 VVHGATATQLDVTWEP--PPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-LAENSVKL 1364
Query: 495 VGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRY 554
L T Y V V AFN+AG+GP S +T + AP P+SV T++ V W
Sbjct: 1365 KNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAP-SAPSSVKFSELTTTSVNVSWEA 1423
Query: 555 VQPTN 559
Q N
Sbjct: 1424 PQFPN 1428
Score = 88.2 bits (209), Expect = 8e-17
Identities = 76/332 (22%), Positives = 140/332 (42%), Gaps = 13/332 (3%)
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
W Y ++QA N +G G P + + T P P NVS + + + W+ +P +
Sbjct: 845 WTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 903
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
+NG + YK+ ++ S+ + + L++ GN + ++ Y Y+V+V AF IG
Sbjct: 904 DRNGLVLGYKVMYKEKDSDTQPRFWLVE--GN-SSRSAQLTGLGKYVLYEVQVLAFTRIG 960
Query: 412 PG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
G P + + +D+P P + +T++ + W P + I HRL
Sbjct: 961 DGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1019
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKA 530
E L+ + R + GL+P++ Y ++ A G G +E + T ++
Sbjct: 1020 TTANTATVEV---LAPSARQYTA-TGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD 1075
Query: 531 PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEH 590
+PP+ V D V+ + ++ P+ Y ++ EL + + H
Sbjct: 1076 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHS--ASVSH 1133
Query: 591 KLEAYI-SNIIPGKSYNLRVLAYSNGGDGRMS 621
++I + P SY RV A ++ GD S
Sbjct: 1134 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 1165
Score = 87.0 bits (206), Expect = 2e-16
Identities = 98/438 (22%), Positives = 177/438 (40%), Gaps = 44/438 (10%)
Query: 212 IEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
++ PGPP G+ ++ +SV L W + I Y +T R ++ N
Sbjct: 974 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR---------LNTTTANT 1024
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN- 330
V+ R +T L P ++Y FRI A G G+ + + D+P + P+
Sbjct: 1025 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP-QPPSRP 1083
Query: 331 -VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
V + + ++W P L P +Y I R S + N +++V
Sbjct: 1084 MVQQEDVRARSVLLSWEPGSDGL--SPVRYYTIQTRELPSG-RWALHSASVSHNASSFIV 1140
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+T Y +V+A NDIG S E ++ + + P AP ++S +T++ +
Sbjct: 1141 DRLKP--FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 1198
Query: 449 WNPIDQSRERLRGKLIGHRLKYWK--QENKEEECIYYLSRTTRNWALIV----------- 495
W P + +++ G L+G R++Y + E + ++ WA +
Sbjct: 1199 WQP--PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 1256
Query: 496 --------GLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTT 547
L Y +++ +N+ GEGP S P P +V V T
Sbjct: 1257 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 1316
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEAYISNIIPGKSYN 606
L V W ++ + GYK+ WE + +++ T+ E+ ++ + N+ +Y
Sbjct: 1317 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK--LKNLTGYTAYM 1374
Query: 607 LRVLAYSNGGDGRMSSPT 624
+ V A++ GDG S+PT
Sbjct: 1375 VSVAAFNAAGDGPRSTPT 1392
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/178 (32%), Positives = 78/178 (43%), Gaps = 13/178 (7%)
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
YE R+ N +G G PS+P + P AP NV G L +TW P P QN
Sbjct: 1272 YEIRMSVYNAVGEG-PSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQN 1330
Query: 355 GPGIHYKI-FWR-RNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
G YKI FW + G+ E L + V + + YT Y V V AFN G
Sbjct: 1331 GDIQGYKIYFWEAQRGNLTERVKTLF-----LAENSVKLKNLTGYTAYMVSVAAFNAAGD 1385
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
GP S + + P AP V +T++NV+W ++ + G L G+RL Y
Sbjct: 1386 GPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNVSW----EAPQFPNGILEGYRLVY 1438
Score = 59.7 bits (138), Expect = 3e-08
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 5/160 (3%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG-KRFITEN-GNLIIRQLSRDDEGVYTCVAKNQ 102
V + C+ + P P+ TW KD V+ RF N G L I L DD G++ C A+N
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNA 62
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G ++ L V + + P T V L C P A W G RI
Sbjct: 63 AGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAP--RPAITW-QKGERIL 119
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
S + + + ++ G L I +SD G Y C+ ++ G
Sbjct: 120 ASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRG 159
Score = 55.6 bits (128), Expect = 5e-07
Identities = 84/369 (22%), Positives = 142/369 (38%), Gaps = 32/369 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P P V L SS+ + W++ R G +L + + S+ P V
Sbjct: 876 PSSGPTNVSALATTSSSMLVRWSEVPEADR--NGLVLGYKVMYKEK---DSDTQPRFWLV 930
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
+ R+ T L + +YE ++ A +G G PS P T D P P +
Sbjct: 931 E--GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 987
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWR-----RNGSEVEFQSLLLKKYGNIGTYVV 389
+T + + W P + NG + Y+I R N + VE + ++Y G +
Sbjct: 988 EVRTTSVRLIWQP--PAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG---L 1042
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ-LVSARSFNSTALNVT 448
S Y + + Q G E+ VVT D PQ + +V + ++ ++
Sbjct: 1043 KPESVYLFR---ITAQTRKGWGEAAEALVVTT-EKRDRPQPPSRPMVQQEDVRARSVLLS 1098
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWA--LIVGLQPDTYYYVK 506
W P +R I R E + + + N + ++ L+P T Y +
Sbjct: 1099 WEPGSDGLSPVRYYTIQTR------ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFR 1152
Query: 507 VMAFNSAGEGPESERYLE-RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLL 565
V A N G+ SE T + AP + P ++V H T++ + W+ LL
Sbjct: 1153 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 1212
Query: 566 GYKVRLWEL 574
G+++R EL
Sbjct: 1213 GFRIRYREL 1221
Score = 35.9 bits (79), Expect = 0.47
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGR 254
EG PGPPG V I+ S++ + W+ + PIT Y++ R
Sbjct: 1499 EGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEAR 1539
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 224 bits (547), Expect = 9e-58
Identities = 174/647 (26%), Positives = 281/647 (43%), Gaps = 67/647 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 424 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 482
Query: 61 WKKDNIVIGAGGKRFIT-ENGNL-------IIRQL---SRDDEGVYTCVAKNQYGTDESR 109
W K ++ ENG L I++++ +D G YTCVA+N+ G ++
Sbjct: 483 WFKGAKGSALHEDIYVLHENGTLEIKDATWIVKEIPVAQKDSTGTYTCVARNKLGMAKNE 542
Query: 110 GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
L P Q S+V C D L LW +KD+ +L
Sbjct: 543 VHL-----------QPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPS 585
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP----------PGPP 219
++R +D L + +VS D G Y CV + + +S+ L + P P PP
Sbjct: 586 DERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPP 645
Query: 220 GGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNG 279
+++ SV L WT + N PIT +++ Y + + P +
Sbjct: 646 FDLELTDQLDKSVQLSWTPGDDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVS 696
Query: 280 RKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTG 339
+ T L P+ Y FR+ A+N +G PS S Q+ T +P + P V G G +
Sbjct: 697 GTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPD 756
Query: 340 DLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTP 399
+L ITW PL NGPG+ YK+ WR+ + E+ S+++ N+ Y+V S T + P
Sbjct: 757 NLEITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVV---ANVSKYIV--SGTPTFVP 811
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERL 459
Y +KVQA ND+G PE VV +S ED+P VAP V NST V W+P+ + +
Sbjct: 812 YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPV--PLKSI 869
Query: 460 RGKLIGHRLKYWKQENKEEECIYYLSRT------TRNWALIVGLQPDTYYYVKVMAFNSA 513
RG L G+R+ YWK ++ + ++ + ++ ++ GL+P ++Y + V N
Sbjct: 870 RGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 929
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
GEGP S +R F P A ++ +PT + + P++ L Y ++
Sbjct: 930 GEGPASP---DRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYTLKYQP 986
Query: 574 LD--QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++ ++ D +P +K + N+ Y A ++ G G
Sbjct: 987 INSTHELGPLVDLKIP-ANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1032
Score = 56.0 bits (129), Expect = 4e-07
Identities = 54/219 (24%), Positives = 84/219 (38%), Gaps = 10/219 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 333 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 389
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 390 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 449
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI-KDSSDLYVNKRIKIDG 177
R L N L C P+ + G + +D L+ N ++I
Sbjct: 450 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIKD 509
Query: 178 GELTIYNVSLS---DVGDYECVVKSAIGRISSHVQLRIE 213
+ + ++ G Y CV ++ +G + V L+ E
Sbjct: 510 ATWIVKEIPVAQKDSTGTYTCVARNKLGMAKNEVHLQPE 548
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 280 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 339
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 340 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 396
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 397 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 448
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 58 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 117
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 118 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 176 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 216
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 115 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 173
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 174 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 216
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 209 bits (510), Expect = 3e-53
Identities = 149/490 (30%), Positives = 232/490 (47%), Gaps = 52/490 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 460
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 519
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 520 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 573
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---------------EGPPGPPGG 221
LTI+ V+ D G Y CV + + + + L + +G P P
Sbjct: 574 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 633
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGR 280
+++ + SV L W ++N PIT Y++ + + P V + +Y G
Sbjct: 634 LELTDLAERSVRLTWIPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGS 684
Query: 281 KRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGD 340
+ V L P+ Y+FR+ AIN +G PS PS ++ TSG P P +V G G + +
Sbjct: 685 VNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 743
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ ITWTP+ + GP + Y + WRR + + ++ + +G+ YVV T Y PY
Sbjct: 744 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPY 797
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+++VQA ND G GPE E V YS ED+P AP+ R N +N+ W+ E
Sbjct: 798 EIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWD----HPEHPN 852
Query: 461 GKLIGHRLKY 470
G +IG+ LKY
Sbjct: 853 GIMIGYTLKY 862
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 175 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 234
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 235 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 286
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 287 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 320
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 321 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 377
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 378 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 58 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 117
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 118 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 176 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/230 (21%), Positives = 89/230 (38%), Gaps = 16/230 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 646 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 700
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 701 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 754
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 755 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 814
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
+ + P P V + T+ + W + P + ++GY ++
Sbjct: 815 SVIGYSGEDLP-SAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 861
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 209 bits (510), Expect = 3e-53
Identities = 149/490 (30%), Positives = 232/490 (47%), Gaps = 52/490 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 374 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 429
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 430 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 488
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 489 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 542
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---------------EGPPGPPGG 221
LTI+ V+ D G Y CV + + + + L + +G P P
Sbjct: 543 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 602
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGR 280
+++ + SV L W ++N PIT Y++ + + P V + +Y G
Sbjct: 603 LELTDLAERSVRLTWIPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGS 653
Query: 281 KRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGD 340
+ V L P+ Y+FR+ AIN +G PS PS ++ TSG P P +V G G + +
Sbjct: 654 VNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 712
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ ITWTP+ + GP + Y + WRR + + ++ + +G+ YVV T Y PY
Sbjct: 713 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPY 766
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+++VQA ND G GPE E V YS ED+P AP+ R N +N+ W+ E
Sbjct: 767 EIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWD----HPEHPN 821
Query: 461 GKLIGHRLKY 470
G +IG+ LKY
Sbjct: 822 GIMIGYTLKY 831
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 85 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 143
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 144 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 203
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 204 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 255
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 256 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 306
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 230 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 289
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 290 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 346
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 347 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 399
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 27 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 86
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 87 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 144
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 145 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 182
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/230 (21%), Positives = 89/230 (38%), Gaps = 16/230 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 615 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 669
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 670 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 723
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 724 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 783
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
+ + P P V + T+ + W + P + ++GY ++
Sbjct: 784 SVIGYSGEDLP-SAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 830
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 209 bits (510), Expect = 3e-53
Identities = 149/490 (30%), Positives = 232/490 (47%), Gaps = 52/490 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 460
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 519
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 520 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 573
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---------------EGPPGPPGG 221
LTI+ V+ D G Y CV + + + + L + +G P P
Sbjct: 574 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRD 633
Query: 222 VQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM-EVDRYNGR 280
+++ + SV L W ++N PIT Y++ + + P V + +Y G
Sbjct: 634 LELTDLAERSVRLTWIPGDANNSPITDYVVQ---------FEEDQFQPGVWHDHSKYPGS 684
Query: 281 KRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGD 340
+ V L P+ Y+FR+ AIN +G PS PS ++ TSG P P +V G G + +
Sbjct: 685 VNSAV-LRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNN 743
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ ITWTP+ + GP + Y + WRR + + ++ + +G+ YVV T Y PY
Sbjct: 744 MEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTV--WGS--RYVV--GQTPVYVPY 797
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+++VQA ND G GPE E V YS ED+P AP+ R N +N+ W+ E
Sbjct: 798 EIRVQAENDFGKGPEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWD----HPEHPN 852
Query: 461 GKLIGHRLKY 470
G +IG+ LKY
Sbjct: 853 GIMIGYTLKY 862
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 175 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 234
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 235 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 286
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 287 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 320
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 321 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 377
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 378 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 58 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 117
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 118 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 176 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 213
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/230 (21%), Positives = 89/230 (38%), Gaps = 16/230 (6%)
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
+TW +P N P Y + + + + K G++ + V+ +S Y Y
Sbjct: 646 LTW--IPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSP---YVNYQF 700
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVA-PQLVSARSFNSTALNVTWNPIDQSRERLRG 461
+V A N++G S Y P + P V + +TW P++ +
Sbjct: 701 RVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNAT------ 754
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY-YYVKVMAFNSAGEGPESE 520
G L+Y + + E + + T +VG P Y ++V A N G+GPE E
Sbjct: 755 SAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPE 814
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
+ + P P V + T+ + W + P + ++GY ++
Sbjct: 815 SVIGYSGEDLP-SAPRRFRVRQPNLETINLEWDH--PEHPNGIMIGYTLK 861
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 200 bits (487), Expect = 2e-50
Identities = 166/636 (26%), Positives = 273/636 (42%), Gaps = 38/636 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
++QC A N+ + L V ++ P F + P++ T ++G L+C+ APKP T
Sbjct: 455 IFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVD--TTVTDGMTAILRCEVSGAPKPAIT 512
Query: 61 WKKDNIVIGAGGKRF----ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
WK++N ++ +G R + E+G L I + D G YTC A N G+ + L V
Sbjct: 513 WKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWN 572
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
+ + + + LHC A DP + Y+W + + + SS RI ++
Sbjct: 573 RTSIVHPPEDHVVIK-GTTATLHCGATHDPRVSLRYVWKKDNVALTPSS----TSRIVVE 627
Query: 177 -GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS--VT 233
G L I D+GDY C + S G S +L + P P + + S V
Sbjct: 628 KDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSHSHAVV 687
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWA 293
L W PI Y + + +S W V N+ M TVS L P
Sbjct: 688 LSWVRPFDGNSPIL-YYIVELSENSSPWKVHLSNVGPEMT--------GVTVSG-LTPAR 737
Query: 294 IYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQ 353
Y+FR+ A+N +G GQ SA + + + P P N+ G + + W P P +
Sbjct: 738 TYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEH 797
Query: 354 NGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPG 413
NG Y + +R G E+Q + + ++ +T Y+++V A+N G G
Sbjct: 798 NGVLRGYILRYRLAGLPGEYQQ---RNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLG 854
Query: 414 PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQ 473
S VT Y+ + +P PQ V + NST + WNP Q + + G G++L W
Sbjct: 855 VFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQ--QFINGINQGYKLLAWPA 912
Query: 474 ENKEEECIYYLSRTTR--NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ E + ++ + I L+ T Y+ V+ F + G+GP S L T P
Sbjct: 913 DAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKP 972
Query: 532 QKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWEL-DQDMSTANDTIVPIEH 590
++ T+L+V W+ +P + + GY++ WE+ ++ S T+ H
Sbjct: 973 -GAVGHLSFTEILDTSLKVSWQ--EPLEKNGIITGYQIS-WEVYGRNDSRLTHTLNSTTH 1028
Query: 591 KLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
E I + +Y + V A + G G ++S TI+
Sbjct: 1029 --EYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTIS 1062
Score = 124 bits (300), Expect = 8e-28
Identities = 109/420 (25%), Positives = 187/420 (44%), Gaps = 31/420 (7%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHW---NSTWYVI--SENIPN 270
PG P + I I S TL++ I+ +++ G+ W + EN P+
Sbjct: 1070 PGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPD 1129
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
++ N L P+ Y FR++ +NI+GP S S T P AP +
Sbjct: 1130 AQMLEIPN----------LTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTS 1179
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNG--PGIHYKI-FWRRNGSEVEFQSLLLKKYGNIGTY 387
V+ L + W PLP S NG + Y+I +WR + ++ + T
Sbjct: 1180 VTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFT- 1238
Query: 388 VVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNV 447
I + Y++++QAFN +G GP SEVV + E +P AP+ VSA + +ST + +
Sbjct: 1239 ---IEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILL 1295
Query: 448 TWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
TW + + + G ++G+++ + ++ E + + AL+ GL+ Y ++V
Sbjct: 1296 TWTSVPEQDQ--NGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQV 1353
Query: 508 MAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+AF G G P + LERT AP PP + T++R+VW+ P +LG
Sbjct: 1354 LAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQ--PPEEPNGIILG 1410
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
Y++ + L S T V + + + +++ P +Y R+ A + G G T+
Sbjct: 1411 YQI-AYRL-ASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATV 1468
Score = 111 bits (268), Expect = 6e-24
Identities = 108/419 (25%), Positives = 174/419 (41%), Gaps = 37/419 (8%)
Query: 216 PGPPGGVQI--LGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PP + + + S+ L+W + PI + + R W S +I +
Sbjct: 1477 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISH--- 1533
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
A V L P+ Y+ R++A N +G S+ + +T D P E P +VS
Sbjct: 1534 ------EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSA 1587
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRR----NGSEVEFQSL-----LLKKYGNI 384
T + I W P NG Y+I++R GS E ++L L +
Sbjct: 1588 TPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALXAELTAQ 1647
Query: 385 GTY-VVHISSTYF---------YTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQL 434
++ V+ SST Y Y+V + A+N IG P S V ++ E P +APQ
Sbjct: 1648 SSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQN 1707
Query: 435 VSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALI 494
V ++ L VTW+P E G + G+++ YW+ +++ E + +
Sbjct: 1708 VQVTPLTASQLEVTWDP--PPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRL 1765
Query: 495 VGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRY 554
L T Y V + AFN+AG+GP+S+ RT + AP P+ + TTL V W
Sbjct: 1766 KNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWG- 1823
Query: 555 VQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY--ISNIIPGKSYNLRVLA 611
+P L GY+V L + V + + + + ++ G +Y RV A
Sbjct: 1824 -EPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 1881
Score = 101 bits (243), Expect = 6e-21
Identities = 110/430 (25%), Positives = 189/430 (43%), Gaps = 29/430 (6%)
Query: 205 SSHVQLRIEGPPG-PPGGVQILGIQRSSVTLEWT---DSNSNGRPIT-GYMLTGRTHWNS 259
SS V ++ PP P V + +S+ L W DS NG P + GY + +W S
Sbjct: 1162 SSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIK---YWRS 1218
Query: 260 TWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ S + V+ DR +R L W YE ++QA N +G G P + + T
Sbjct: 1219 D--LQSSAVAQVVS-DRL---EREFTIEELEEWMEYELQMQAFNAVGAG-PWSEVVRGRT 1271
Query: 320 SGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLK 379
P AP NVS + + +TWT +P QNG + YKI +R + E +S +++
Sbjct: 1272 RESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVR 1331
Query: 380 KYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSAR 438
GN T ++ + Y+++V AF IG G P + ++ + +D P +LV
Sbjct: 1332 --GN-HTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPE 1388
Query: 439 SFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQ 498
T++ + W P ++ + G I +RL + + T R + L
Sbjct: 1389 -VRLTSVRIVWQPPEEPNGIILGYQIAYRLA---SSSPHTFTTVEVGATVRQFTA-TDLA 1443
Query: 499 PDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPT 558
P++ Y ++ A G G E + T ++ PP + V + T + ++V +
Sbjct: 1444 PESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGS 1503
Query: 559 NEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEA-YISNIIPGKSYNLRVLAYSNGG 616
+ P+ + +++ EL + + T + +I H+ A + + P SY LR+ A ++ G
Sbjct: 1504 DGASPIRYFTMQVRELPRGEWQTYSSSI---SHEATACVVDRLRPFTSYKLRLKATNDIG 1560
Query: 617 DGRMSSPTIA 626
D SS T A
Sbjct: 1561 DSDFSSETEA 1570
Score = 85.0 bits (201), Expect = 8e-16
Identities = 62/232 (26%), Positives = 104/232 (44%), Gaps = 8/232 (3%)
Query: 400 YDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y +V A N++G G S E + E+ P P+ + A + ++ V W P ++
Sbjct: 739 YQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHN 798
Query: 459 --LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
LRG ++ +RL E ++ ++ N+ L+ L T Y ++V A+N AG G
Sbjct: 799 GVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLG 854
Query: 517 PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
S E T + P PP +V A + TT++ +W GYK+ W D
Sbjct: 855 VFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADA 914
Query: 577 DMSTANDTIVPIEHKLE-AYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAF 627
+ TI P H + +I+N+ +Y VL ++ GDG S+P + +
Sbjct: 915 PEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVW 966
Score = 81.0 bits (191), Expect = 1e-14
Identities = 104/432 (24%), Positives = 168/432 (38%), Gaps = 34/432 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWT---DSNSNGRPITGYMLTGRT-HWNSTWYVISENIPN 270
P PPG V SSV ++W D + NG + GY + R + + ++ + N
Sbjct: 1578 PGEPPGSVSATPHTTSSVLIQWQPPRDESLNGL-LQGYRIYYRELEYEAGSGTEAKTLKN 1636
Query: 271 VM----EVDRYNGRKRATVSTT--------LLPWAIYEFRIQAINILGPGQPSAPSPQFS 318
+ E+ + K S+T L + YE + A NI+G SAP F
Sbjct: 1637 PIALXAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFV 1696
Query: 319 TSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLL 378
P AP NV L +TW P P QNG YKI++ S+ E + +
Sbjct: 1697 GEA-APAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKM-- 1753
Query: 379 KKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSAR 438
K + VV + + +T Y V + AFN G GP+S+ + + P AP ++
Sbjct: 1754 -KVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG-APSFLAFS 1811
Query: 439 SFNSTALNVTWNPIDQSRERLRGKLIGHRLKY---WKQENKEEECIYYLSRTTRNWALIV 495
ST LNV+W G L G+R+ Y + + + + W +
Sbjct: 1812 EITSTTLNVSWG----EPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVR 1867
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYV 555
L Y+ +V A + GPE + + + P V V + L + W
Sbjct: 1868 DLTKGVTYFFRVQA-RTITYGPELQANITAGPAEGSPGSPRDVLV-TKSASELTLQW--T 1923
Query: 556 QPTNEEEPLLGYKVRLWELDQDMSTANDTIVP-IEHKLEAYISNIIPGKSYNLRVLAYSN 614
+ + + P GY + D+ + +P + + G +Y RV+A +
Sbjct: 1924 EGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNE 1983
Query: 615 GGDGRMSSPTIA 626
G G S+P+ A
Sbjct: 1984 AGYGEPSNPSTA 1995
Score = 62.1 bits (144), Expect = 6e-09
Identities = 55/217 (25%), Positives = 90/217 (41%), Gaps = 12/217 (5%)
Query: 2 YQCEAK---NQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y CEA + + + ++A L ++ P F P E V + C+ P PT
Sbjct: 360 YVCEAALPGSAFEPARATAFLFIIE-PPYFTAEP-ESRISAEVEETVDIGCQAMGVPLPT 417
Query: 59 FTWKKDNIVIGA-GGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I I R+ + +G L I++L +D G++ C A N+ G ++ L V
Sbjct: 418 LQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTN 477
Query: 117 -APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
AP F ++ P T L C P A W I S + + + + +
Sbjct: 478 IAPVFTQR-PVDTTVTDGMTAILRCEVSGAP--KPAITWKREN-HILASGSVRIPRFMLL 533
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ G L I V + D G+Y C + G +++ L +
Sbjct: 534 ESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTV 570
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P V + S +TL+WT+ +S P TGY++ R W + ++IP
Sbjct: 1900 EGSPGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPR-- 1956
Query: 273 EVDRYNGRKRATVSTTLLPWAI-YEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
Y T+S L + YEFR+ A+N G G+PS PS S + P+
Sbjct: 1957 SATSY------TLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 2004
Score = 51.6 bits (118), Expect = 9e-06
Identities = 68/302 (22%), Positives = 121/302 (40%), Gaps = 21/302 (6%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L + +YE ++ A +G G PS P T D P P + + + I W P
Sbjct: 1343 LRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQP- 1400
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY--TPYDVKVQA 406
P NG + Y+I +R S + + +G V ++T + Y ++ A
Sbjct: 1401 PEE-PNGIILGYQIAYRLASSSPHTFTTV-----EVGATVRQFTATDLAPESAYIFRLSA 1454
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQ---LVSARSFNSTALNVTWNPIDQSRERLRGKL 463
G G E T+ + E + AP LV + +L + W P +R
Sbjct: 1455 KTRQGWGEPLEA-TVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIR--- 1510
Query: 464 IGHRLKYWKQENKEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGP-ESER 521
+ ++ + E Y S + A +V L+P T Y +++ A N G+ SE
Sbjct: 1511 --YFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSET 1568
Query: 522 YLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTA 581
T + P +PP SV+ H +++ + W+ + + L GY++ EL+ + +
Sbjct: 1569 EAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSG 1628
Query: 582 ND 583
+
Sbjct: 1629 TE 1630
Score = 46.8 bits (106), Expect = 2e-04
Identities = 51/206 (24%), Positives = 78/206 (37%), Gaps = 22/206 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTFT 60
Y+C +N++ A ++ SF + +T S+G L P + P+P T
Sbjct: 167 YRCVVRNRMGALLQRKSEVQVAYMGSFMDTD-QRKTV-SQGRAAILNLLPITSYPRPQVT 224
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W ++ I + IT L+I + D G Y A N+ + I L R
Sbjct: 225 WFREGHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARD 284
Query: 121 L---EKLPPRITAQV--------NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
+ E + P I +S L C A P+ D + W NG+RI +
Sbjct: 285 VGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF- 343
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYEC 195
G LTI N + +D G Y C
Sbjct: 344 -------GRHLTISNPTSADTGPYVC 362
Score = 34.3 bits (75), Expect = 1.4
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 6/79 (7%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIR 85
P FK P L EG + L C E + F W +D+ + + II
Sbjct: 104 PYFKTEP-GLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEY-----KYIIP 157
Query: 86 QLSRDDEGVYTCVAKNQYG 104
L + D G Y CV +N+ G
Sbjct: 158 SLQKLDAGFYRCVVRNRMG 176
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 174 bits (424), Expect = 7e-43
Identities = 148/564 (26%), Positives = 241/564 (42%), Gaps = 34/564 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 419 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 475
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 476 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 535
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 536 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 592
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 593 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKAR 651
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + +S W ++ +V AT+ +
Sbjct: 652 TITLRWTMGFDGNSPITGYDIECKNKSDS-W----DSAQRTKDVSPQ--LNSATI-IDIH 703
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPL 348
P + Y R+ A N +G S PS + + + D+ P P V + + +TW
Sbjct: 704 PSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAP 760
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
LQNG Y+I +R + FQ ++ + + V + + +T Y + VQA N
Sbjct: 761 KKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACN 820
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L G L G R+
Sbjct: 821 RAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALNGILQGFRV 878
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
YW E TT+ + GL+ T Y ++V+AF AG+G SE+ RT
Sbjct: 879 IYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKE 938
Query: 529 KAPQKPPASVNVWAHDPTTLRVVW 552
P PPA V A + + V W
Sbjct: 939 DVP-GPPAGVKAAAASASMVFVSW 961
Score = 79.0 bits (186), Expect = 5e-14
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H SSTY +++ A N IG S +TI + E P PQ V +S ++ VT
Sbjct: 702 IHPSSTY-----SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 756
Query: 449 WNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W + + +RG IG+R +Y N + I + + L T Y +
Sbjct: 757 WKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLV 815
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
V A N AG GP S+ + T P PP +V A P ++ + W + L G
Sbjct: 816 VQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 875
Query: 567 YKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++V W +D ++ + I + LE + + +Y+++VLA++ GDG
Sbjct: 876 FRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYTNYSIQVLAFTRAGDG 926
Score = 64.5 bits (150), Expect = 1e-09
Identities = 48/163 (29%), Positives = 75/163 (46%), Gaps = 8/163 (4%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P+P + W KDN+ + G+ T G L+I + D G Y C N+YGT + GRL V
Sbjct: 4 PEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 62
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
+ P P ++ + V S V L C+ V D W NG + ++ +
Sbjct: 63 -KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEILNPGKNVRIT---G 116
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 117 INHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 159
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 325 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 381
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 382 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 441
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 442 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 499
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 500 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 539
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 1054 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1113
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 1114 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 1168
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 1169 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1224
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 1225 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 1273
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 233 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 288
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 289 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 348
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 349 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 402
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 403 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 442
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 176 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 235
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 236 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 293
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 294 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 347
Query: 215 PP 216
PP
Sbjct: 348 PP 349
Score = 42.3 bits (95), Expect = 0.005
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 2/147 (1%)
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
N A I+ + P + Y +++ A N G+ S AP PP V++ ++R
Sbjct: 695 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 754
Query: 550 VVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI-VPIEHKLEAY-ISNIIPGKSYNL 607
V W+ + + + GY++ E + + I V E Y + N+ Y L
Sbjct: 755 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 814
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
V A + G G S I + D S
Sbjct: 815 VVQACNRAGTGPSSQEIITTTLEDVPS 841
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 1119 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 1172
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 1173 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 1228
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 2012
Score = 174 bits (424), Expect = 7e-43
Identities = 148/564 (26%), Positives = 241/564 (42%), Gaps = 34/564 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 667 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 723
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 724 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 784 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 840
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 841 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKAR 899
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + +S W ++ +V AT+ +
Sbjct: 900 TITLRWTMGFDGNSPITGYDIECKNKSDS-W----DSAQRTKDVSPQ--LNSATI-IDIH 951
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPL 348
P + Y R+ A N +G S PS + + + D+ P P V + + +TW
Sbjct: 952 PSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAP 1008
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
LQNG Y+I +R + FQ ++ + + V + + +T Y + VQA N
Sbjct: 1009 KKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACN 1068
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L G L G R+
Sbjct: 1069 RAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALNGILQGFRV 1126
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
YW E TT+ + GL+ T Y ++V+AF AG+G SE+ RT
Sbjct: 1127 IYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKE 1186
Query: 529 KAPQKPPASVNVWAHDPTTLRVVW 552
P PPA V A + + V W
Sbjct: 1187 DVP-GPPAGVKAAAASASMVFVSW 1209
Score = 79.0 bits (186), Expect = 5e-14
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H SSTY +++ A N IG S +TI + E P PQ V +S ++ VT
Sbjct: 950 IHPSSTY-----SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 1004
Query: 449 WNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W + + +RG IG+R +Y N + I + + L T Y +
Sbjct: 1005 WKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLV 1063
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
V A N AG GP S+ + T P PP +V A P ++ + W + L G
Sbjct: 1064 VQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 1123
Query: 567 YKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++V W +D ++ + I + LE + + +Y+++VLA++ GDG
Sbjct: 1124 FRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYTNYSIQVLAFTRAGDG 1174
Score = 71.7 bits (168), Expect = 8e-12
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G V L CK P+P + W KDN+ + G+ T G L+I + D G Y C N
Sbjct: 239 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSN 297
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+YGT + GRL V + P P ++ + V S V L C+ V D W NG +
Sbjct: 298 RYGTAKVIGRLYV-KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEIL 354
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
++ + I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 355 NPGKNVRIT---GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 407
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 573 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 629
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 630 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 690 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 747
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 748 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 787
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 1362 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 1416
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 1417 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1472
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 1473 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 1521
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 481 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 536
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 537 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 597 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 650
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 651 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 690
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 424 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 483
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 484 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 541
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 542 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 595
Query: 215 PP 216
PP
Sbjct: 596 PP 597
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 30/229 (13%)
Query: 2 YQCEAKNQL-KASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
Y C A+N K ++ + +P + + +E + GNV + KC ++ +
Sbjct: 100 YYCTAENPSGKIRSQDVHIKAVLREP----YTVRVEDQKTMRGNVAVFKCIIPSSVEAYI 155
Query: 60 T---WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYT--CVAKNQYGTDESR----G 110
T W+KD + + +G + IT G L I+ + +D G+Y C+ +++Y T E+R
Sbjct: 156 TVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNED-GLYNYRCITRHRY-TGETRQSNSA 213
Query: 111 RLIVL----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
RL V AP L+ R A V L C A P D Y W +KD+
Sbjct: 214 RLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALGHPEPD--YRW------LKDNMP 264
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L ++ R + L I N+ SD G Y C V + G +L ++ P
Sbjct: 265 LELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313
Score = 42.3 bits (95), Expect = 0.005
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 2/147 (1%)
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
N A I+ + P + Y +++ A N G+ S AP PP V++ ++R
Sbjct: 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 1002
Query: 550 VVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI-VPIEHKLEAY-ISNIIPGKSYNL 607
V W+ + + + GY++ E + + I V E Y + N+ Y L
Sbjct: 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1062
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
V A + G G S I + D S
Sbjct: 1063 VVQACNRAGTGPSSQEIITTTLEDVPS 1089
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 1367 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 1420
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 1421 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 1476
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1571
Score = 174 bits (424), Expect = 7e-43
Identities = 148/564 (26%), Positives = 241/564 (42%), Gaps = 34/564 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 667 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 723
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 724 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 783
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 784 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 840
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 841 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKAR 899
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + +S W ++ +V AT+ +
Sbjct: 900 TITLRWTMGFDGNSPITGYDIECKNKSDS-W----DSAQRTKDVSPQ--LNSATI-IDIH 951
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPL 348
P + Y R+ A N +G S PS + + + D+ P P V + + +TW
Sbjct: 952 PSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAP 1008
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
LQNG Y+I +R + FQ ++ + + V + + +T Y + VQA N
Sbjct: 1009 KKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACN 1068
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L G L G R+
Sbjct: 1069 RAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALNGILQGFRV 1126
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
YW E TT+ + GL+ T Y ++V+AF AG+G SE+ RT
Sbjct: 1127 IYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKE 1186
Query: 529 KAPQKPPASVNVWAHDPTTLRVVW 552
P PPA V A + + V W
Sbjct: 1187 DVP-GPPAGVKAAAASASMVFVSW 1209
Score = 79.0 bits (186), Expect = 5e-14
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H SSTY +++ A N IG S +TI + E P PQ V +S ++ VT
Sbjct: 950 IHPSSTY-----SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 1004
Query: 449 WNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W + + +RG IG+R +Y N + I + + L T Y +
Sbjct: 1005 WKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLV 1063
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
V A N AG GP S+ + T P PP +V A P ++ + W + L G
Sbjct: 1064 VQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 1123
Query: 567 YKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++V W +D ++ + I + LE + + +Y+++VLA++ GDG
Sbjct: 1124 FRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYTNYSIQVLAFTRAGDG 1174
Score = 71.7 bits (168), Expect = 8e-12
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G V L CK P+P + W KDN+ + G+ T G L+I + D G Y C N
Sbjct: 239 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSN 297
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+YGT + GRL V + P P ++ + V S V L C+ V D W NG +
Sbjct: 298 RYGTAKVIGRLYV-KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEIL 354
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
++ + I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 355 NPGKNVRIT---GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 407
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 573 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 629
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 630 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 690 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 747
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 748 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 787
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 1302 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 1362 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 1416
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 1417 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1472
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 1473 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 1521
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 481 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 536
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 537 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 597 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 650
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 651 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 690
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 424 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 483
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 484 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 541
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 542 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 595
Query: 215 PP 216
PP
Sbjct: 596 PP 597
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 30/229 (13%)
Query: 2 YQCEAKNQL-KASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
Y C A+N K ++ + +P + + +E + GNV + KC ++ +
Sbjct: 100 YYCTAENPSGKIRSQDVHIKAVLREP----YTVRVEDQKTMRGNVAVFKCIIPSSVEAYI 155
Query: 60 T---WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYT--CVAKNQYGTDESR----G 110
T W+KD + + +G + IT G L I+ + +D G+Y C+ +++Y T E+R
Sbjct: 156 TVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNED-GLYNYRCITRHRY-TGETRQSNSA 213
Query: 111 RLIVL----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
RL V AP L+ R A V L C A P D Y W +KD+
Sbjct: 214 RLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALGHPEPD--YRW------LKDNMP 264
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L ++ R + L I N+ SD G Y C V + G +L ++ P
Sbjct: 265 LELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 313
Score = 42.3 bits (95), Expect = 0.005
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 2/147 (1%)
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
N A I+ + P + Y +++ A N G+ S AP PP V++ ++R
Sbjct: 943 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 1002
Query: 550 VVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI-VPIEHKLEAY-ISNIIPGKSYNL 607
V W+ + + + GY++ E + + I V E Y + N+ Y L
Sbjct: 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1062
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
V A + G G S I + D S
Sbjct: 1063 VVQACNRAGTGPSSQEIITTTLEDVPS 1089
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 1367 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 1420
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 1421 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 1476
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1896
Score = 174 bits (424), Expect = 7e-43
Identities = 148/564 (26%), Positives = 241/564 (42%), Gaps = 34/564 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 653 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 709
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 710 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 769
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 770 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 826
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 827 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKAR 885
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + +S W ++ +V AT+ +
Sbjct: 886 TITLRWTMGFDGNSPITGYDIECKNKSDS-W----DSAQRTKDVSPQ--LNSATI-IDIH 937
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPL 348
P + Y R+ A N +G S PS + + + D+ P P V + + +TW
Sbjct: 938 PSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAP 994
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
LQNG Y+I +R + FQ ++ + + V + + +T Y + VQA N
Sbjct: 995 KKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACN 1054
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L G L G R+
Sbjct: 1055 RAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALNGILQGFRV 1112
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
YW E TT+ + GL+ T Y ++V+AF AG+G SE+ RT
Sbjct: 1113 IYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKE 1172
Query: 529 KAPQKPPASVNVWAHDPTTLRVVW 552
P PPA V A + + V W
Sbjct: 1173 DVP-GPPAGVKAAAASASMVFVSW 1195
Score = 79.0 bits (186), Expect = 5e-14
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H SSTY +++ A N IG S +TI + E P PQ V +S ++ VT
Sbjct: 936 IHPSSTY-----SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 990
Query: 449 WNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W + + +RG IG+R +Y N + I + + L T Y +
Sbjct: 991 WKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLV 1049
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
V A N AG GP S+ + T P PP +V A P ++ + W + L G
Sbjct: 1050 VQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 1109
Query: 567 YKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++V W +D ++ + I + LE + + +Y+++VLA++ GDG
Sbjct: 1110 FRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYTNYSIQVLAFTRAGDG 1160
Score = 71.7 bits (168), Expect = 8e-12
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G V L CK P+P + W KDN+ + G+ T G L+I + D G Y C N
Sbjct: 225 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSN 283
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+YGT + GRL V + P P ++ + V S V L C+ V D W NG +
Sbjct: 284 RYGTAKVIGRLYV-KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEIL 340
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
++ + I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 341 NPGKNVRIT---GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 393
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 559 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 615
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 616 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 675
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 676 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 733
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 734 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 773
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 1288 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1347
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 1348 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 1402
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 1403 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1458
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 1459 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 1507
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 467 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 522
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 523 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 582
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 583 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 636
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 637 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 676
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 410 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 469
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 470 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 527
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 528 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 581
Query: 215 PP 216
PP
Sbjct: 582 PP 583
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 30/229 (13%)
Query: 2 YQCEAKNQL-KASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
Y C A+N K ++ + +P + + +E + GNV + KC ++ +
Sbjct: 86 YYCTAENPSGKIRSQDVHIKAVLREP----YTVRVEDQKTMRGNVAVFKCIIPSSVEAYI 141
Query: 60 T---WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYT--CVAKNQYGTDESR----G 110
T W+KD + + +G + IT G L I+ + +D G+Y C+ +++Y T E+R
Sbjct: 142 TVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNED-GLYNYRCITRHRY-TGETRQSNSA 199
Query: 111 RLIVL----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
RL V AP L+ R A V L C A P D Y W +KD+
Sbjct: 200 RLFVSDPANSAPSILDGFDHR-KAMAGQRVELPCKALGHPEPD--YRW------LKDNMP 250
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L ++ R + L I N+ SD G Y C V + G +L ++ P
Sbjct: 251 LELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 299
Score = 42.3 bits (95), Expect = 0.005
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 2/147 (1%)
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
N A I+ + P + Y +++ A N G+ S AP PP V++ ++R
Sbjct: 929 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 988
Query: 550 VVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI-VPIEHKLEAY-ISNIIPGKSYNL 607
V W+ + + + GY++ E + + I V E Y + N+ Y L
Sbjct: 989 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1048
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
V A + G G S I + D S
Sbjct: 1049 VVQACNRAGTGPSSQEIITTTLEDVPS 1075
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 1353 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 1406
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 1407 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 1462
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhesion
molecule isoform CHD2-42 precursor variant protein.
Length = 2023
Score = 174 bits (424), Expect = 7e-43
Identities = 148/564 (26%), Positives = 241/564 (42%), Gaps = 34/564 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 678 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 734
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 735 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 794
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 795 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 851
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 852 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPE-IEIKDVKAR 910
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + +S W ++ +V AT+ +
Sbjct: 911 TITLRWTMGFDGNSPITGYDIECKNKSDS-W----DSAQRTKDVSPQ--LNSATI-IDIH 962
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPL 348
P + Y R+ A N +G S PS + + + D+ P P V + + +TW
Sbjct: 963 PSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAP 1019
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
LQNG Y+I +R + FQ ++ + + V + + +T Y + VQA N
Sbjct: 1020 KKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACN 1079
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L G L G R+
Sbjct: 1080 RAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALNGILQGFRV 1137
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
YW E TT+ + GL+ T Y ++V+AF AG+G SE+ RT
Sbjct: 1138 IYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKE 1197
Query: 529 KAPQKPPASVNVWAHDPTTLRVVW 552
P PPA V A + + V W
Sbjct: 1198 DVP-GPPAGVKAAAASASMVFVSW 1220
Score = 79.0 bits (186), Expect = 5e-14
Identities = 63/234 (26%), Positives = 103/234 (44%), Gaps = 13/234 (5%)
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H SSTY +++ A N IG S +TI + E P PQ V +S ++ VT
Sbjct: 961 IHPSSTY-----SIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVT 1015
Query: 449 WNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W + + +RG IG+R +Y N + I + + L T Y +
Sbjct: 1016 WKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLV 1074
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
V A N AG GP S+ + T P PP +V A P ++ + W + L G
Sbjct: 1075 VQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQG 1134
Query: 567 YKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
++V W +D ++ + I + LE + + +Y+++VLA++ GDG
Sbjct: 1135 FRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYTNYSIQVLAFTRAGDG 1185
Score = 71.7 bits (168), Expect = 8e-12
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G V L CK P+P + W KDN+ + G+ T G L+I + D G Y C N
Sbjct: 250 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSN 308
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+YGT + GRL V + P P ++ + V S V L C+ V D W NG +
Sbjct: 309 RYGTAKVIGRLYV-KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEIL 365
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
++ + I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 366 NPGKNVRIT---GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 418
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 584 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 640
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 641 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 700
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 701 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 758
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 759 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 798
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 1313 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1372
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 1373 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 1427
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 1428 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 1483
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 1484 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 1532
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 492 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 547
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 548 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 607
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 608 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 661
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 662 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 701
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 435 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 494
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 495 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 552
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 553 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 606
Query: 215 PP 216
PP
Sbjct: 607 PP 608
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/229 (27%), Positives = 100/229 (43%), Gaps = 30/229 (13%)
Query: 2 YQCEAKNQL-KASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
Y C A+N K ++ + +P + + +E + GNV + KC ++ +
Sbjct: 111 YYCTAENPSGKIRSQDVHIKAVLREP----YTVRVEDQKTMRGNVAVFKCIIPSSVEAYI 166
Query: 60 T---WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYT--CVAKNQYGTDESR----G 110
T W+KD + + +G + IT G L I+ + +D G+Y C+ +++Y T E+R
Sbjct: 167 TVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNED-GLYNYRCITRHRY-TGETRQSNSA 224
Query: 111 RLIVL----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
RL V AP L+ R A V L C A P D Y W +KD+
Sbjct: 225 RLFVSDPANSAPSILDGFEHR-KAMAGQRVELPCKALGHPEPD--YRW------LKDNMP 275
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L ++ R + L I N+ SD G Y C V + G +L ++ P
Sbjct: 276 LELSGRFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQP 324
Score = 42.3 bits (95), Expect = 0.005
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 2/147 (1%)
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
N A I+ + P + Y +++ A N G+ S AP PP V++ ++R
Sbjct: 954 NSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIR 1013
Query: 550 VVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI-VPIEHKLEAY-ISNIIPGKSYNL 607
V W+ + + + GY++ E + + I V E Y + N+ Y L
Sbjct: 1014 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1073
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
V A + G G S I + D S
Sbjct: 1074 VVQACNRAGTGPSSQEIITTTLEDVPS 1100
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 1378 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 1431
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 1432 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 1487
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 160 bits (389), Expect = 1e-38
Identities = 159/636 (25%), Positives = 264/636 (41%), Gaps = 41/636 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELE-TYGSEGGNVTLKCKPEAAPKPTFT 60
Y C A N A+ S + ++ + P F P + YG G L C + P P
Sbjct: 727 YTCIASNAA-ATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPPKVM 782
Query: 61 WK--------KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL 112
WK + + G+ I N +L+IR + +D G Y C A N GTD S+
Sbjct: 783 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 842
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNK 171
+ ++ P + P A L+C A + PI+ W I +
Sbjct: 843 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPII---IRWEKGDTVIDPDRVMRYAI 899
Query: 172 RIKIDGGEL-TIYNVSLSDVGD---YECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
K +G E+ + + +D GD + C ++ G +QL ++ PP PP ++I +
Sbjct: 900 ATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREV 958
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVST 287
+ S+ L WT ITG+ + + +S + ++ N+ +A +
Sbjct: 959 KARSMNLRWTQRFDGNSIITGFDIEYKNKSDS--WDFKQSTRNISPTIN-----QANI-V 1010
Query: 288 TLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
L P ++Y R+ + N +G +PS ST P P +V+ + + +TW
Sbjct: 1011 DLHPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKA 1069
Query: 348 LPTSLQNGPGIHYKIFWRRN--GSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQ 405
LQNG Y+I +R N GS ++ + +K G+ Y + + + Y V VQ
Sbjct: 1070 PKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYT--LDNLKKFAQYGVVVQ 1127
Query: 406 AFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIG 465
AFN G GP S + + ED+P P+ V A S S ++W+ + R L G L G
Sbjct: 1128 AFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWS--EPPRSTLNGVLKG 1185
Query: 466 HRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
+R+ +W E TTR + G++ T Y V+V+A+ AG+G S +
Sbjct: 1186 YRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQ 1245
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P PPA + +++ V W + PT + Y + ++
Sbjct: 1246 TKEDVP-GPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE 1302
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
E +L I+++ G+ Y L V A ++ G G S
Sbjct: 1303 TSPE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1337
Score = 80.2 bits (189), Expect = 2e-14
Identities = 133/555 (23%), Positives = 207/555 (37%), Gaps = 51/555 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + S + + + HP T +G L C W
Sbjct: 825 YLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERPIIIRW 882
Query: 62 KKDNIVIGAGG-KRFIT---ENGNLIIRQLS-----RDDEGVYTCVAKNQYGTDESRGRL 112
+K + VI R+ +NG+ ++ L R D ++C A N YG D +L
Sbjct: 883 EKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQL 942
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
V P PP + ++ V N D + + K+ SD + K+
Sbjct: 943 TVQEPPD-----PPEL--EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQ 995
Query: 173 ----IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE----GPPGPPGGVQI 224
I + I ++ + V + IGR +L I P GPP V +
Sbjct: 996 STRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTL 1055
Query: 225 LGIQRSSVTLEWTDSNS---NGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
+ S+ + W NG I GY + R NS S +++E+ + G
Sbjct: 1056 QPVTSQSIQVTWKAPKKELQNG-VIRGYQIGYRE--NSPG---SNGQYSIVEM-KATGDS 1108
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
L +A Y +QA N G G PS+ +T D P + P NV +
Sbjct: 1109 EVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPPENVRALSITSDVA 1167
Query: 342 TITWTPLPTSLQNGPGIHYK-IFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
I+W+ P S NG Y+ IFW +G E Q++ + V + +T
Sbjct: 1168 VISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER------VELRGMEKFT 1221
Query: 399 PYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y V+V A+ G G S V+ I + ED+P P + A +++++ V+W P +
Sbjct: 1222 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVVSWLPPTKPNGV 1280
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+R I Q E Y + + + I L Y + V A SAG G
Sbjct: 1281 IRKYTIFCSSPGSGQPAPSE----YETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1336
Query: 519 SERYLERTFRKAPQK 533
SE+ KAP K
Sbjct: 1337 SEKVTIEPAGKAPAK 1351
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER- 458
Y +++ +FN IG S+ +TI + E P P V+ + S ++ VTW + +
Sbjct: 1018 YSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 1077
Query: 459 -LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+RG IG+R + N + + + + L+ Y V V AFN AG GP
Sbjct: 1078 VIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGP 1136
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
S T P +PP +V + + W + L GY+V W L D
Sbjct: 1137 SSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVD 1196
Query: 578 MSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
I ++E + + +Y+++VLAY+ GDG SS
Sbjct: 1197 GEWGEMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSS 1240
Score = 60.1 bits (139), Expect = 3e-08
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
+Y+C A+N + ++ A++ V PS + + + G TL C+ P +
Sbjct: 542 VYRCTARNLVGSAEYQARINVRG-PPSIRA----MRNITAVAGRDTLINCRVIGYPYYSI 596
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD +++ ++ + ENG L + + + DEG Y C Q S+ + ++ P
Sbjct: 597 KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 656
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
++ + PP Q+ + + + D+ PI T W +G I S + + + +
Sbjct: 657 PLIQPFEFPPASIGQLLYIPCVVSSGDM-PIRIT---WRKDGQVIISGSGVTIESKEFMS 712
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VSL G+Y C+ +A +S QL + PP
Sbjct: 713 S--LQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPP 750
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/198 (23%), Positives = 75/198 (37%), Gaps = 11/198 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE----GGNVTLKCKPEAAPKP 57
Y+C K++ + LS+ + P L+ + S+ G V L C P P
Sbjct: 256 YRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIP 315
Query: 58 TFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W KD + A R+ L I L +D G Y C N +G+ E+ G L+V+
Sbjct: 316 AIRWLKDGRPLPADS-RWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI-D 373
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P + P ++ + S V L C P + W N + + + +
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSP--EFTIRWYRNTELVLPDEAISIR---GLSN 428
Query: 178 GELTIYNVSLSDVGDYEC 195
L I + S G Y+C
Sbjct: 429 ETLLITSAQKSHSGAYQC 446
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
+V L C P P W KD+ I + G R I NG L++R + +D G YTC A
Sbjct: 1366 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1425
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRIT---AQVNSVVFLHCNADVDPILDTAYLWNH 156
N G D L+V P PR+T +S+ D ++ +
Sbjct: 1426 TNTGGFDTIIVNLLVQVPPD-----QPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1480
Query: 157 NGLRIKDSSDLYVN---KRIKIDGGEL-TIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ ++ D++++ + K+D + T Y V L+ GRIS ++ +
Sbjct: 1481 SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSV------GSGRISEIIEAKT 1534
Query: 213 EG--PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
G P I + L N+ G PIT +L R W + N
Sbjct: 1535 HGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSG 1594
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ + + AT W YE R++A N G G +A QF+T
Sbjct: 1595 EVFLTEL---REAT-------W--YELRMRACNSAGCGNETA---QFAT 1628
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT-FT 60
Y C Q + S S + + + P + P E S G + + C + P T
Sbjct: 633 YLCSVLIQPQLSISQSVHVAVKVPPLIQ--PFEFPP-ASIGQLLYIPCVVSSGDMPIRIT 689
Query: 61 WKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD VI +G I +L I +S G YTC+A N T +LIV
Sbjct: 690 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 749
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH--NGLRIKDSSDLYVNKRIKI 175
PRF+ + P L+C+ D P +W H + + + RI+I
Sbjct: 750 PRFVVQ-PNNQDGIYGKAGVLNCSVDGYP--PPKVMWKHAKGSGNPQQYHPVPLTGRIQI 806
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
L I +V D+G Y C + +G IS + L ++ P
Sbjct: 807 LPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 848
Score = 47.2 bits (107), Expect = 2e-04
Identities = 61/213 (28%), Positives = 92/213 (43%), Gaps = 24/213 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTL-KCK-PEAAPK-- 56
Y C A+N S +RV K F++ + + +E S GNV + KC P + +
Sbjct: 161 YFCTAENAA-GKIRSPNIRV---KAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYV 216
Query: 57 PTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDE-GVYTCVAKNQYG--TDESRG-RL 112
+W+KD + I + FIT +G L I + ++D Y C+ K++Y T +S G RL
Sbjct: 217 SVVSWEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARL 276
Query: 113 IVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
V + + +Q V L C A PI A W +G + +D
Sbjct: 277 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPI--PAIRWLKDGRPL--PADSRW 332
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
KRI LTI ++ D G Y C V + G
Sbjct: 333 TKRIT----GLTISDLRTEDSGTYICEVTNTFG 361
Score = 43.2 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CE N ++ ++ L V+ P +L+T G V L C +P+ T W
Sbjct: 352 YICEVTNTFGSAEATGILMVID-PLHVTLTPKKLKT--GIGSTVILSCALTGSPEFTIRW 408
Query: 62 KKDNIVIGAGGKRFIT--ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR--A 117
++ ++ I N L+I + G Y C A + T + +I L
Sbjct: 409 YRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFA-IIALEDGT 467
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PR + ++ L C A P + + + ++D S N+ DG
Sbjct: 468 PRIVSSFSEKVV-NPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHR-TNQYTMSDG 524
Query: 178 GELTIYNVS---LSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ NV+ + D G Y C ++ +G ++ + GPP
Sbjct: 525 TTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 566
Score = 40.7 bits (91), Expect = 0.016
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 427 MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSR 486
+P P+L +++ +++++ +TW P D +RG ++ + + +N EE ++S
Sbjct: 1442 VPPDQPRLTVSKT-SASSITLTWIPGDNGGSSIRGFVLQYSV-----DNSEEWKDVFISS 1495
Query: 487 TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ R++ L L+ T+Y VK+ A NS G G SE +T + P
Sbjct: 1496 SERSFKLD-SLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREP 1539
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule DSCAML1 protein.
Length = 2053
Score = 160 bits (389), Expect = 1e-38
Identities = 159/636 (25%), Positives = 264/636 (41%), Gaps = 41/636 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELE-TYGSEGGNVTLKCKPEAAPKPTFT 60
Y C A N A+ S + ++ + P F P + YG G L C + P P
Sbjct: 667 YTCIASNAA-ATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPPKVM 722
Query: 61 WK--------KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL 112
WK + + G+ I N +L+IR + +D G Y C A N GTD S+
Sbjct: 723 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 782
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNK 171
+ ++ P + P A L+C A + PI+ W I +
Sbjct: 783 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPII---IRWEKGDTVIDPDRVMRYAI 839
Query: 172 RIKIDGGEL-TIYNVSLSDVGD---YECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
K +G E+ + + +D GD + C ++ G +QL ++ PP PP ++I +
Sbjct: 840 ATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREV 898
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVST 287
+ S+ L WT ITG+ + + +S + ++ N+ +A +
Sbjct: 899 KARSMNLRWTQRFDGNSIITGFDIEYKNKSDS--WDFKQSTRNISPTIN-----QANI-V 950
Query: 288 TLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
L P ++Y R+ + N +G +PS ST P P +V+ + + +TW
Sbjct: 951 DLHPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKA 1009
Query: 348 LPTSLQNGPGIHYKIFWRRN--GSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQ 405
LQNG Y+I +R N GS ++ + +K G+ Y + + + Y V VQ
Sbjct: 1010 PKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYT--LDNLKKFAQYGVVVQ 1067
Query: 406 AFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIG 465
AFN G GP S + + ED+P P+ V A S S ++W+ + R L G L G
Sbjct: 1068 AFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWS--EPPRSTLNGVLKG 1125
Query: 466 HRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
+R+ +W E TTR + G++ T Y V+V+A+ AG+G S +
Sbjct: 1126 YRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQ 1185
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P PPA + +++ V W + PT + Y + ++
Sbjct: 1186 TKEDVP-GPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE 1242
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
E +L I+++ G+ Y L V A ++ G G S
Sbjct: 1243 TSPE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1277
Score = 80.2 bits (189), Expect = 2e-14
Identities = 133/555 (23%), Positives = 207/555 (37%), Gaps = 51/555 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + S + + + HP T +G L C W
Sbjct: 765 YLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERPIIIRW 822
Query: 62 KKDNIVIGAGG-KRFIT---ENGNLIIRQLS-----RDDEGVYTCVAKNQYGTDESRGRL 112
+K + VI R+ +NG+ ++ L R D ++C A N YG D +L
Sbjct: 823 EKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQL 882
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
V P PP + ++ V N D + + K+ SD + K+
Sbjct: 883 TVQEPPD-----PPEL--EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQ 935
Query: 173 ----IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE----GPPGPPGGVQI 224
I + I ++ + V + IGR +L I P GPP V +
Sbjct: 936 STRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTL 995
Query: 225 LGIQRSSVTLEWTDSNS---NGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
+ S+ + W NG I GY + R NS S +++E+ + G
Sbjct: 996 QPVTSQSIQVTWKAPKKELQNG-VIRGYQIGYRE--NSPG---SNGQYSIVEM-KATGDS 1048
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
L +A Y +QA N G G PS+ +T D P + P NV +
Sbjct: 1049 EVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPPENVRALSITSDVA 1107
Query: 342 TITWTPLPTSLQNGPGIHYK-IFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
I+W+ P S NG Y+ IFW +G E Q++ + V + +T
Sbjct: 1108 VISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER------VELRGMEKFT 1161
Query: 399 PYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y V+V A+ G G S V+ I + ED+P P + A +++++ V+W P +
Sbjct: 1162 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVVSWLPPTKPNGV 1220
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+R I Q E Y + + + I L Y + V A SAG G
Sbjct: 1221 IRKYTIFCSSPGSGQPAPSE----YETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1276
Query: 519 SERYLERTFRKAPQK 533
SE+ KAP K
Sbjct: 1277 SEKVTIEPAGKAPAK 1291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER- 458
Y +++ +FN IG S+ +TI + E P P V+ + S ++ VTW + +
Sbjct: 958 YSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 1017
Query: 459 -LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+RG IG+R + N + + + + L+ Y V V AFN AG GP
Sbjct: 1018 VIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGP 1076
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
S T P +PP +V + + W + L GY+V W L D
Sbjct: 1077 SSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVD 1136
Query: 578 MSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
I ++E + + +Y+++VLAY+ GDG SS
Sbjct: 1137 GEWGEMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSS 1180
Score = 60.1 bits (139), Expect = 3e-08
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
+Y+C A+N + ++ A++ V PS + + + G TL C+ P +
Sbjct: 482 VYRCTARNLVGSAEYQARINVRG-PPSIRA----MRNITAVAGRDTLINCRVIGYPYYSI 536
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD +++ ++ + ENG L + + + DEG Y C Q S+ + ++ P
Sbjct: 537 KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 596
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
++ + PP Q+ + + + D+ PI T W +G I S + + + +
Sbjct: 597 PLIQPFEFPPASIGQLLYIPCVVSSGDM-PIRIT---WRKDGQVIISGSGVTIESKEFMS 652
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VSL G+Y C+ +A +S QL + PP
Sbjct: 653 S--LQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPP 690
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/198 (23%), Positives = 75/198 (37%), Gaps = 11/198 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE----GGNVTLKCKPEAAPKP 57
Y+C K++ + LS+ + P L+ + S+ G V L C P P
Sbjct: 196 YRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIP 255
Query: 58 TFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W KD + A R+ L I L +D G Y C N +G+ E+ G L+V+
Sbjct: 256 AIRWLKDGRPLPADS-RWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI-D 313
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P + P ++ + S V L C P + W N + + + +
Sbjct: 314 PLHVTLTPKKLKTGIGSTVILSCALTGSP--EFTIRWYRNTELVLPDEAISIR---GLSN 368
Query: 178 GELTIYNVSLSDVGDYEC 195
L I + S G Y+C
Sbjct: 369 ETLLITSAQKSHSGAYQC 386
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
+V L C P P W KD+ I + G R I NG L++R + +D G YTC A
Sbjct: 1306 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1365
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRIT---AQVNSVVFLHCNADVDPILDTAYLWNH 156
N G D L+V P PR+T +S+ D ++ +
Sbjct: 1366 TNTGGFDTIIVNLLVQVPPD-----QPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1420
Query: 157 NGLRIKDSSDLYVN---KRIKIDGGEL-TIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ ++ D++++ + K+D + T Y V L+ GRIS ++ +
Sbjct: 1421 SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSV------GSGRISEIIEAKT 1474
Query: 213 EG--PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
G P I + L N+ G PIT +L R W + N
Sbjct: 1475 HGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSG 1534
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ + + AT W YE R++A N G G +A QF+T
Sbjct: 1535 EVFLTEL---REAT-------W--YELRMRACNSAGCGNETA---QFAT 1568
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT-FT 60
Y C Q + S S + + + P + P E S G + + C + P T
Sbjct: 573 YLCSVLIQPQLSISQSVHVAVKVPPLIQ--PFEFPP-ASIGQLLYIPCVVSSGDMPIRIT 629
Query: 61 WKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD VI +G I +L I +S G YTC+A N T +LIV
Sbjct: 630 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 689
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH--NGLRIKDSSDLYVNKRIKI 175
PRF+ + P L+C+ D P +W H + + + RI+I
Sbjct: 690 PRFVVQ-PNNQDGIYGKAGVLNCSVDGYP--PPKVMWKHAKGSGNPQQYHPVPLTGRIQI 746
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
L I +V D+G Y C + +G IS + L ++ P
Sbjct: 747 LPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 788
Score = 48.0 bits (109), Expect = 1e-04
Identities = 61/213 (28%), Positives = 92/213 (43%), Gaps = 24/213 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTL-KCK-PEAAPK-- 56
Y C A+N S +RV K F++ + + +E S GNV + KC P + +
Sbjct: 101 YFCTAENAA-GKIRSPNIRV---KAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYV 156
Query: 57 PTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDE-GVYTCVAKNQYG--TDESRG-RL 112
+W+KD + I + FIT +G L I + ++D Y C+ K++Y T +S G RL
Sbjct: 157 SVVSWEKDTVSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARL 216
Query: 113 IVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
V + + +Q V L C A PI A W +G + +D
Sbjct: 217 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPI--PAIRWLKDGRPL--PADSRW 272
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
KRI LTI ++ D G Y C V + G
Sbjct: 273 TKRIT----GLTISDLRTEDSGTYICEVTNTFG 301
Score = 43.2 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CE N ++ ++ L V+ P +L+T G V L C +P+ T W
Sbjct: 292 YICEVTNTFGSAEATGILMVID-PLHVTLTPKKLKT--GIGSTVILSCALTGSPEFTIRW 348
Query: 62 KKDNIVIGAGGKRFIT--ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR--A 117
++ ++ I N L+I + G Y C A + T + +I L
Sbjct: 349 YRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFA-IIALEDGT 407
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PR + ++ L C A P + + + ++D S N+ DG
Sbjct: 408 PRIVSSFSEKVV-NPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHR-TNQYTMSDG 464
Query: 178 GELTIYNVS---LSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ NV+ + D G Y C ++ +G ++ + GPP
Sbjct: 465 TTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Score = 40.7 bits (91), Expect = 0.016
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 427 MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSR 486
+P P+L +++ +++++ +TW P D +RG ++ + + +N EE ++S
Sbjct: 1382 VPPDQPRLTVSKT-SASSITLTWIPGDNGGSSIRGFVLQYSV-----DNSEEWKDVFISS 1435
Query: 487 TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ R++ L L+ T+Y VK+ A NS G G SE +T + P
Sbjct: 1436 SERSFKLD-SLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREP 1479
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 160 bits (389), Expect = 1e-38
Identities = 159/636 (25%), Positives = 264/636 (41%), Gaps = 41/636 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELE-TYGSEGGNVTLKCKPEAAPKPTFT 60
Y C A N A+ S + ++ + P F P + YG G L C + P P
Sbjct: 706 YTCIASNAA-ATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPPKVM 761
Query: 61 WK--------KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRL 112
WK + + G+ I N +L+IR + +D G Y C A N GTD S+
Sbjct: 762 WKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMF 821
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNK 171
+ ++ P + P A L+C A + PI+ W I +
Sbjct: 822 LTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPII---IRWEKGDTVIDPDRVMRYAI 878
Query: 172 RIKIDGGEL-TIYNVSLSDVGD---YECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
K +G E+ + + +D GD + C ++ G +QL ++ PP PP ++I +
Sbjct: 879 ATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREV 937
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVST 287
+ S+ L WT ITG+ + + +S + ++ N+ +A +
Sbjct: 938 KARSMNLRWTQRFDGNSIITGFDIEYKNKSDS--WDFKQSTRNISPTIN-----QANI-V 989
Query: 288 TLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
L P ++Y R+ + N +G +PS ST P P +V+ + + +TW
Sbjct: 990 DLHPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKA 1048
Query: 348 LPTSLQNGPGIHYKIFWRRN--GSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQ 405
LQNG Y+I +R N GS ++ + +K G+ Y + + + Y V VQ
Sbjct: 1049 PKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYT--LDNLKKFAQYGVVVQ 1106
Query: 406 AFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIG 465
AFN G GP S + + ED+P P+ V A S S ++W+ + R L G L G
Sbjct: 1107 AFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWS--EPPRSTLNGVLKG 1164
Query: 466 HRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
+R+ +W E TTR + G++ T Y V+V+A+ AG+G S +
Sbjct: 1165 YRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQ 1224
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P PPA + +++ V W + PT + Y + ++
Sbjct: 1225 TKEDVP-GPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYE 1281
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
E +L I+++ G+ Y L V A ++ G G S
Sbjct: 1282 TSPE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1316
Score = 80.2 bits (189), Expect = 2e-14
Identities = 133/555 (23%), Positives = 207/555 (37%), Gaps = 51/555 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + S + + + HP T +G L C W
Sbjct: 804 YLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERPIIIRW 861
Query: 62 KKDNIVIGAGG-KRFIT---ENGNLIIRQLS-----RDDEGVYTCVAKNQYGTDESRGRL 112
+K + VI R+ +NG+ ++ L R D ++C A N YG D +L
Sbjct: 862 EKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQL 921
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
V P PP + ++ V N D + + K+ SD + K+
Sbjct: 922 TVQEPPD-----PPEL--EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQ 974
Query: 173 ----IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE----GPPGPPGGVQI 224
I + I ++ + V + IGR +L I P GPP V +
Sbjct: 975 STRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTL 1034
Query: 225 LGIQRSSVTLEWTDSNS---NGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
+ S+ + W NG I GY + R NS S +++E+ + G
Sbjct: 1035 QPVTSQSIQVTWKAPKKELQNG-VIRGYQIGYRE--NSPG---SNGQYSIVEM-KATGDS 1087
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
L +A Y +QA N G G PS+ +T D P + P NV +
Sbjct: 1088 EVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPPENVRALSITSDVA 1146
Query: 342 TITWTPLPTSLQNGPGIHYK-IFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
I+W+ P S NG Y+ IFW +G E Q++ + V + +T
Sbjct: 1147 VISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER------VELRGMEKFT 1200
Query: 399 PYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y V+V A+ G G S V+ I + ED+P P + A +++++ V+W P +
Sbjct: 1201 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVVSWLPPTKPNGV 1259
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+R I Q E Y + + + I L Y + V A SAG G
Sbjct: 1260 IRKYTIFCSSPGSGQPAPSE----YETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1315
Query: 519 SERYLERTFRKAPQK 533
SE+ KAP K
Sbjct: 1316 SEKVTIEPAGKAPAK 1330
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER- 458
Y +++ +FN IG S+ +TI + E P P V+ + S ++ VTW + +
Sbjct: 997 YSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 1056
Query: 459 -LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+RG IG+R + N + + + + L+ Y V V AFN AG GP
Sbjct: 1057 VIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGP 1115
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
S T P +PP +V + + W + L GY+V W L D
Sbjct: 1116 SSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVD 1175
Query: 578 MSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
I ++E + + +Y+++VLAY+ GDG SS
Sbjct: 1176 GEWGEMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSS 1219
Score = 60.1 bits (139), Expect = 3e-08
Identities = 53/220 (24%), Positives = 98/220 (44%), Gaps = 15/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
+Y+C A+N + ++ A++ V PS + + + G TL C+ P +
Sbjct: 521 VYRCTARNLVGSAEYQARINVRG-PPSIRA----MRNITAVAGRDTLINCRVIGYPYYSI 575
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD +++ ++ + ENG L + + + DEG Y C Q S+ + ++ P
Sbjct: 576 KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 635
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
++ + PP Q+ + + + D+ PI T W +G I S + + + +
Sbjct: 636 PLIQPFEFPPASIGQLLYIPCVVSSGDM-PIRIT---WRKDGQVIISGSGVTIESKEFMS 691
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VSL G+Y C+ +A +S QL + PP
Sbjct: 692 S--LQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPP 729
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/198 (23%), Positives = 75/198 (37%), Gaps = 11/198 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE----GGNVTLKCKPEAAPKP 57
Y+C K++ + LS+ + P L+ + S+ G V L C P P
Sbjct: 235 YRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIP 294
Query: 58 TFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W KD + A R+ L I L +D G Y C N +G+ E+ G L+V+
Sbjct: 295 AIRWLKDGRPLPADS-RWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI-D 352
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P + P ++ + S V L C P + W N + + + +
Sbjct: 353 PLHVTLTPKKLKTGIGSTVILSCALTGSP--EFTIRWYRNTELVLPDEAISIR---GLSN 407
Query: 178 GELTIYNVSLSDVGDYEC 195
L I + S G Y+C
Sbjct: 408 ETLLITSAQKSHSGAYQC 425
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
+V L C P P W KD+ I + G R I NG L++R + +D G YTC A
Sbjct: 1345 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1404
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRIT---AQVNSVVFLHCNADVDPILDTAYLWNH 156
N G D L+V P PR+T +S+ D ++ +
Sbjct: 1405 TNTGGFDTIIVNLLVQVPPD-----QPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1459
Query: 157 NGLRIKDSSDLYVN---KRIKIDGGEL-TIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ ++ D++++ + K+D + T Y V L+ GRIS ++ +
Sbjct: 1460 SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSV------GSGRISEIIEAKT 1513
Query: 213 EG--PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
G P I + L N+ G PIT +L R W + N
Sbjct: 1514 HGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSG 1573
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ + + AT W YE R++A N G G +A QF+T
Sbjct: 1574 EVFLTEL---REAT-------W--YELRMRACNSAGCGNETA---QFAT 1607
Score = 49.2 bits (112), Expect = 5e-05
Identities = 58/222 (26%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT-FT 60
Y C Q + S S + + + P + P E S G + + C + P T
Sbjct: 612 YLCSVLIQPQLSISQSVHVAVKVPPLIQ--PFEFPP-ASIGQLLYIPCVVSSGDMPIRIT 668
Query: 61 WKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD VI +G I +L I +S G YTC+A N T +LIV
Sbjct: 669 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 728
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH--NGLRIKDSSDLYVNKRIKI 175
PRF+ + P L+C+ D P +W H + + + RI+I
Sbjct: 729 PRFVVQ-PNNQDGIYGKAGVLNCSVDGYP--PPKVMWKHAKGSGNPQQYHPVPLTGRIQI 785
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
L I +V D+G Y C + +G IS + L ++ P
Sbjct: 786 LPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 827
Score = 48.0 bits (109), Expect = 1e-04
Identities = 61/213 (28%), Positives = 92/213 (43%), Gaps = 24/213 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTL-KCK-PEAAPK-- 56
Y C A+N S +RV K F++ + + +E S GNV + KC P + +
Sbjct: 140 YFCTAENAA-GKIRSPNIRV---KAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYV 195
Query: 57 PTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDE-GVYTCVAKNQYG--TDESRG-RL 112
+W+KD + I + FIT +G L I + ++D Y C+ K++Y T +S G RL
Sbjct: 196 SVVSWEKDTVSIIPENRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARL 255
Query: 113 IVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
V + + +Q V L C A PI A W +G + +D
Sbjct: 256 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPI--PAIRWLKDGRPL--PADSRW 311
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
KRI LTI ++ D G Y C V + G
Sbjct: 312 TKRIT----GLTISDLRTEDSGTYICEVTNTFG 340
Score = 43.2 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CE N ++ ++ L V+ P +L+T G V L C +P+ T W
Sbjct: 331 YICEVTNTFGSAEATGILMVID-PLHVTLTPKKLKT--GIGSTVILSCALTGSPEFTIRW 387
Query: 62 KKDNIVIGAGGKRFIT--ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR--A 117
++ ++ I N L+I + G Y C A + T + +I L
Sbjct: 388 YRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFA-IIALEDGT 446
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PR + ++ L C A P + + + ++D S N+ DG
Sbjct: 447 PRIVSSFSEKVV-NPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHR-TNQYTMSDG 503
Query: 178 GELTIYNVS---LSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ NV+ + D G Y C ++ +G ++ + GPP
Sbjct: 504 TTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 545
Score = 40.7 bits (91), Expect = 0.016
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 427 MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSR 486
+P P+L +++ +++++ +TW P D +RG ++ + + +N EE ++S
Sbjct: 1421 VPPDQPRLTVSKT-SASSITLTWIPGDNGGSSIRGFVLQYSV-----DNSEEWKDVFISS 1474
Query: 487 TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ R++ L L+ T+Y VK+ A NS G G SE +T + P
Sbjct: 1475 SERSFKLD-SLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREP 1518
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 159 bits (386), Expect = 3e-38
Identities = 152/595 (25%), Positives = 252/595 (42%), Gaps = 57/595 (9%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGA-GGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G +V L C P PT W K+ + +R + G+L I ++ DD G Y C+A
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
N T E++ L V P FL K P I A + + C P W NG
Sbjct: 323 DNGNETIEAQAELTVQAQPEFL-KQPTNIYAHESMDIVFECEVTGKPT--PTVKWVKNGD 379
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI------- 212
+ S + K L + + SD G Y+C+ ++ +G + QL I
Sbjct: 380 MVIPSDYFKIVKE-----HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 213 EGP-PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
GP P P V + + L W S+ G LT + + E + N
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH---GDNLTYSVFYTKEG-IARERVENT 490
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-N 330
+ G + T+ L+P +Y FR+ A N G G+ SAP + T + PA N
Sbjct: 491 S----HPGEMQVTIQN-LMPATVYIFRVMAQNKHGSGESSAPL-RVETQPEVQLPGPAPN 544
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
+ +T+TW P S NG +YK+++ G++ E Q + ++ ++
Sbjct: 545 LRAYAASPTSITVTWET-PVS-GNGEIQNYKLYYMEKGTDKE-QDV------DVSSHSYT 595
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
I+ YT Y +V A+N GPG + V + + D+P APQ +S NS ++ + W
Sbjct: 596 INGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQ 655
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
P + + G++ G++++Y K K + +S T + LI GL T Y +V A
Sbjct: 656 PPAPATQ--NGQITGYKIRYRKASRKSDVTETLVSGTQLS-QLIEGLDRGTEYNFRVAAL 712
Query: 511 NSAGEGPESERYLERTFR------KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPL 564
G GP ++ TF + P+ P+S++V P +V + P N+ +
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPE-VPSSLHV---RPLVTSIVVSWTPPENQNIVV 768
Query: 565 LGYKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
GY + + + + + +++K Y I N+ P Y + + A++N G+G
Sbjct: 769 RGYAI-----GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 116 bits (278), Expect = 4e-25
Identities = 133/533 (24%), Positives = 223/533 (41%), Gaps = 50/533 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + A+L V + +P F K P + Y E ++ +C+ P PT W
Sbjct: 318 YFCIADNGNETIEAQAELTVQA-QPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKW 374
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K+ ++ I + NL + L + DEG Y C+A+N G ++ +LI+L AP
Sbjct: 375 VKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 121 LEKLP--PR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
LP PR + A + S F+ P D ++ + + + +R++
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRT-PASDPH--GDNLTYSVFYTKEGIARERVENTS 491
Query: 178 --GEL--TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP-----PGPPGGVQILGIQ 228
GE+ TI N+ + V + + ++ G S LR+E PGP ++
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+S+T+ W S I Y L Y + + +VD +
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKL----------YYMEKGTDKEQDVD---VSSHSYTING 598
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L + Y FR+ A N GPG S P T D P AP N+S + + I W P
Sbjct: 599 LKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH-ISSTYFYTPYDVKVQAF 407
+ QNG YKI +R+ + + L+ GT + I T Y+ +V A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVS-----GTQLSQLIEGLDRGTEYNFRVAAL 712
Query: 408 NDIGPGPESEVVTIYSAE-DMPQV-APQLVSARSFNS--TALNVTWNPIDQSRERLRGKL 463
G GP ++ ++ + E D+ + P++ S+ T++ V+W P + +RG
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYA 772
Query: 464 IGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
IG+ + + + + Y R + I L P ++Y + + AFN+ GEG
Sbjct: 773 IGYGI---GSPHAQTIKVDYKQR----YYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 71.3 bits (167), Expect = 1e-11
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 20/193 (10%)
Query: 35 LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIG--AGGKRFITENGNLIIRQL----- 87
++T G +V L C + P P WKKD + + +R + +G+L I +
Sbjct: 60 VDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKH 119
Query: 88 SRDDEGVYTCVAK-NQYGTDESR-GRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADV 144
++ DEG Y CVA GT SR +LIV PRF + P + A N+++ NAD+
Sbjct: 120 NKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADL 179
Query: 145 DPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS-AIGR 203
P + W N + L ++ IK+ G L I N + D G Y CVV+S +
Sbjct: 180 VPFV----RWEQNRQPL-----LLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPK 230
Query: 204 ISSHVQLRIEGPP 216
S V+L++ P
Sbjct: 231 YSDEVELKVLPDP 243
Score = 46.4 bits (105), Expect = 3e-04
Identities = 53/209 (25%), Positives = 82/209 (39%), Gaps = 18/209 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP GVQ + ++ + W D N P +T ++ W NIP +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWAD---NSLP-KHQKITDSRYYTVRW---KTNIPANTKY 905
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK-PYEAPANVS- 332
N + + T L P +YEF + G + T+ + P P +V+
Sbjct: 906 KNANATTLSYLVTGLKPNTLYEFSVMVTK--GRRSSTWSMTAHGTTFELVPTSPPKDVTV 963
Query: 333 -GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH- 390
GK + + W P S NG Y I++ + + E +++ +G + H
Sbjct: 964 VSKEGKPKTIIVNWQP--PSEANGKITGYIIYYSTDVN-AEIHDWVIEPV--VGNRLTHQ 1018
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
I TPY K+QA N G GP SE V
Sbjct: 1019 IQELTLDTPYYFKIQARNSKGMGPMSEAV 1047
Score = 45.6 bits (103), Expect = 6e-04
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 470 YWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
++ +E E + S I L P T Y +VMA N G G S T +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE 535
Query: 530 APQKPPA-SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPI 588
PA ++ +A PT++ V W P + + YK L+ +++ D V
Sbjct: 536 VQLPGPAPNLRAYAASPTSITVTWE--TPVSGNGEIQNYK--LYYMEKGTDKEQDVDVS- 590
Query: 589 EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQ-IGDYHSEA 636
H I+ + Y+ RV+AY+ G G +S+P +A + + D S A
Sbjct: 591 SHSYT--INGLKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAA 636
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/199 (23%), Positives = 79/199 (39%), Gaps = 12/199 (6%)
Query: 428 PQVAPQLVSARSFNSTALNVTW--NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLS 485
P + P V A + + +TW N + + ++ + R WK +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR---WKTNIPANTKYKNAN 909
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHD- 544
TT ++ L+ GL+P+T Y VM S TF P PP V V + +
Sbjct: 910 ATTLSY-LVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 545 -PTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVP-IEHKLEAYISNIIPG 602
P T+ V W+ P+ + GY + + D + + I P + ++L I +
Sbjct: 969 KPKTIIVNWQ--PPSEANGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLD 1025
Query: 603 KSYNLRVLAYSNGGDGRMS 621
Y ++ A ++ G G MS
Sbjct: 1026 TPYYFKIQARNSKGMGPMS 1044
Score = 33.9 bits (74), Expect = 1.9
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYYYV 505
V W P ++ GK+ G+ + Y N E + + R I L DT YY
Sbjct: 975 VNWQPPSEAN----GKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYF 1030
Query: 506 KVMAFNSAGEGPESERYLERT 526
K+ A NS G GP SE RT
Sbjct: 1031 KIQARNSKGMGPMSEAVQFRT 1051
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 159 bits (386), Expect = 3e-38
Identities = 152/595 (25%), Positives = 252/595 (42%), Gaps = 57/595 (9%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGA-GGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G +V L C P PT W K+ + +R + G+L I ++ DD G Y C+A
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
N T E++ L V P FL K P I A + + C P W NG
Sbjct: 323 DNGNETIEAQAELTVQAQPEFL-KQPTNIYAHESMDIVFECEVTGKPT--PTVKWVKNGD 379
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI------- 212
+ S + K L + + SD G Y+C+ ++ +G + QL I
Sbjct: 380 MVIPSDYFKIVKE-----HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 213 EGP-PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
GP P P V + + L W S+ G LT + + E + N
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH---GDNLTYSVFYTKEG-IARERVENT 490
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-N 330
+ G + T+ L+P +Y FR+ A N G G+ SAP + T + PA N
Sbjct: 491 S----HPGEMQVTIQN-LMPATVYIFRVMAQNKHGSGESSAPL-RVETQPEVQLPGPAPN 544
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
+ +T+TW P S NG +YK+++ G++ E Q + ++ ++
Sbjct: 545 LRAYAASPTSITVTWET-PVS-GNGEIQNYKLYYMEKGTDKE-QDV------DVSSHSYT 595
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
I+ YT Y +V A+N GPG + V + + D+P APQ +S NS ++ + W
Sbjct: 596 INGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQ 655
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
P + + G++ G++++Y K K + +S T + LI GL T Y +V A
Sbjct: 656 PPAPATQ--NGQITGYKIRYRKASRKSDVTETLVSGTQLS-QLIEGLDRGTEYNFRVAAL 712
Query: 511 NSAGEGPESERYLERTFR------KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPL 564
G GP ++ TF + P+ P+S++V P +V + P N+ +
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPE-VPSSLHV---RPLVTSIVVSWTPPENQNIVV 768
Query: 565 LGYKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
GY + + + + + +++K Y I N+ P Y + + A++N G+G
Sbjct: 769 RGYAI-----GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 116 bits (278), Expect = 4e-25
Identities = 133/533 (24%), Positives = 223/533 (41%), Gaps = 50/533 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + A+L V + +P F K P + Y E ++ +C+ P PT W
Sbjct: 318 YFCIADNGNETIEAQAELTVQA-QPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKW 374
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K+ ++ I + NL + L + DEG Y C+A+N G ++ +LI+L AP
Sbjct: 375 VKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 121 LEKLP--PR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
LP PR + A + S F+ P D ++ + + + +R++
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRT-PASDPH--GDNLTYSVFYTKEGIARERVENTS 491
Query: 178 --GEL--TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP-----PGPPGGVQILGIQ 228
GE+ TI N+ + V + + ++ G S LR+E PGP ++
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+S+T+ W S I Y L Y + + +VD +
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKL----------YYMEKGTDKEQDVD---VSSHSYTING 598
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L + Y FR+ A N GPG S P T D P AP N+S + + I W P
Sbjct: 599 LKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH-ISSTYFYTPYDVKVQAF 407
+ QNG YKI +R+ + + L+ GT + I T Y+ +V A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVS-----GTQLSQLIEGLDRGTEYNFRVAAL 712
Query: 408 NDIGPGPESEVVTIYSAE-DMPQV-APQLVSARSFNS--TALNVTWNPIDQSRERLRGKL 463
G GP ++ ++ + E D+ + P++ S+ T++ V+W P + +RG
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYA 772
Query: 464 IGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
IG+ + + + + Y R + I L P ++Y + + AFN+ GEG
Sbjct: 773 IGYGI---GSPHAQTIKVDYKQR----YYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 70.5 bits (165), Expect = 2e-11
Identities = 57/192 (29%), Positives = 86/192 (44%), Gaps = 18/192 (9%)
Query: 35 LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIG--AGGKRFITENGNLIIRQL----- 87
++T G +V L C + P P WKKD + + +R + +G+L I +
Sbjct: 60 VDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKH 119
Query: 88 SRDDEGVYTCVAK-NQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD 145
++ DEG Y CVA GT SR +LIV PRF + P N + L+C + D
Sbjct: 120 NKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNGAI-LNCEVNAD 178
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS-AIGRI 204
+ + N L + D + IK+ G L I N + D G Y CVV+S +
Sbjct: 179 LVPFVRWEQNRQPLLLDD-------RVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKY 231
Query: 205 SSHVQLRIEGPP 216
S V+L++ P
Sbjct: 232 SDEVELKVLPDP 243
Score = 46.4 bits (105), Expect = 3e-04
Identities = 53/209 (25%), Positives = 82/209 (39%), Gaps = 18/209 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP GVQ + ++ + W D N P +T ++ W NIP +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWAD---NSLP-KHQKITDSRYYTVRW---KTNIPANTKY 905
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK-PYEAPANVS- 332
N + + T L P +YEF + G + T+ + P P +V+
Sbjct: 906 KNANATTLSYLVTGLKPNTLYEFSVMVTK--GRRSSTWSMTAHGTTFELVPTSPPKDVTV 963
Query: 333 -GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH- 390
GK + + W P S NG Y I++ + + E +++ +G + H
Sbjct: 964 VSKEGKPKTIIVNWQP--PSEANGKITGYIIYYSTDVN-AEIHDWVIEPV--VGNRLTHQ 1018
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
I TPY K+QA N G GP SE V
Sbjct: 1019 IQELTLDTPYYFKIQARNSKGMGPMSEAV 1047
Score = 45.6 bits (103), Expect = 6e-04
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 470 YWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
++ +E E + S I L P T Y +VMA N G G S T +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE 535
Query: 530 APQKPPA-SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPI 588
PA ++ +A PT++ V W P + + YK L+ +++ D V
Sbjct: 536 VQLPGPAPNLRAYAASPTSITVTWE--TPVSGNGEIQNYK--LYYMEKGTDKEQDVDVS- 590
Query: 589 EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQ-IGDYHSEA 636
H I+ + Y+ RV+AY+ G G +S+P +A + + D S A
Sbjct: 591 SHSYT--INGLKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAA 636
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/199 (23%), Positives = 79/199 (39%), Gaps = 12/199 (6%)
Query: 428 PQVAPQLVSARSFNSTALNVTW--NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLS 485
P + P V A + + +TW N + + ++ + R WK +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR---WKTNIPANTKYKNAN 909
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHD- 544
TT ++ L+ GL+P+T Y VM S TF P PP V V + +
Sbjct: 910 ATTLSY-LVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 545 -PTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVP-IEHKLEAYISNIIPG 602
P T+ V W+ P+ + GY + + D + + I P + ++L I +
Sbjct: 969 KPKTIIVNWQ--PPSEANGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLD 1025
Query: 603 KSYNLRVLAYSNGGDGRMS 621
Y ++ A ++ G G MS
Sbjct: 1026 TPYYFKIQARNSKGMGPMS 1044
Score = 33.9 bits (74), Expect = 1.9
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYYYV 505
V W P ++ GK+ G+ + Y N E + + R I L DT YY
Sbjct: 975 VNWQPPSEAN----GKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYF 1030
Query: 506 KVMAFNSAGEGPESERYLERT 526
K+ A NS G GP SE RT
Sbjct: 1031 KIQARNSKGMGPMSEAVQFRT 1051
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 159 bits (386), Expect = 3e-38
Identities = 152/595 (25%), Positives = 252/595 (42%), Gaps = 57/595 (9%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGA-GGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G +V L C P PT W K+ + +R + G+L I ++ DD G Y C+A
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIA 322
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
N T E++ L V P FL K P I A + + C P W NG
Sbjct: 323 DNGNETIEAQAELTVQAQPEFL-KQPTNIYAHESMDIVFECEVTGKPT--PTVKWVKNGD 379
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI------- 212
+ S + K L + + SD G Y+C+ ++ +G + QL I
Sbjct: 380 MVIPSDYFKIVKE-----HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 213 EGP-PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
GP P P V + + L W S+ G LT + + E + N
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRTPASDPH---GDNLTYSVFYTKEG-IARERVENT 490
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-N 330
+ G + T+ L+P +Y FR+ A N G G+ SAP + T + PA N
Sbjct: 491 S----HPGEMQVTIQN-LMPATVYIFRVMAQNKHGSGESSAPL-RVETQPEVQLPGPAPN 544
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
+ +T+TW P S NG +YK+++ G++ E Q + ++ ++
Sbjct: 545 LRAYAASPTSITVTWET-PVS-GNGEIQNYKLYYMEKGTDKE-QDV------DVSSHSYT 595
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
I+ YT Y +V A+N GPG + V + + D+P APQ +S NS ++ + W
Sbjct: 596 INGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQ 655
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
P + + G++ G++++Y K K + +S T + LI GL T Y +V A
Sbjct: 656 PPAPATQ--NGQITGYKIRYRKASRKSDVTETLVSGTQLS-QLIEGLDRGTEYNFRVAAL 712
Query: 511 NSAGEGPESERYLERTFR------KAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPL 564
G GP ++ TF + P+ P+S++V P +V + P N+ +
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPE-VPSSLHV---RPLVTSIVVSWTPPENQNIVV 768
Query: 565 LGYKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
GY + + + + + +++K Y I N+ P Y + + A++N G+G
Sbjct: 769 RGYAI-----GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 116 bits (278), Expect = 4e-25
Identities = 133/533 (24%), Positives = 223/533 (41%), Gaps = 50/533 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + A+L V + +P F K P + Y E ++ +C+ P PT W
Sbjct: 318 YFCIADNGNETIEAQAELTVQA-QPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKW 374
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K+ ++ I + NL + L + DEG Y C+A+N G ++ +LI+L AP
Sbjct: 375 VKNGDMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPAT 434
Query: 121 LEKLP--PR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
LP PR + A + S F+ P D ++ + + + +R++
Sbjct: 435 TGPLPSAPRDVVASLVSTRFIKLTWRT-PASDPH--GDNLTYSVFYTKEGIARERVENTS 491
Query: 178 --GEL--TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP-----PGPPGGVQILGIQ 228
GE+ TI N+ + V + + ++ G S LR+E PGP ++
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+S+T+ W S I Y L Y + + +VD +
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKL----------YYMEKGTDKEQDVD---VSSHSYTING 598
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L + Y FR+ A N GPG S P T D P AP N+S + + I W P
Sbjct: 599 LKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH-ISSTYFYTPYDVKVQAF 407
+ QNG YKI +R+ + + L+ GT + I T Y+ +V A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVS-----GTQLSQLIEGLDRGTEYNFRVAAL 712
Query: 408 NDIGPGPESEVVTIYSAE-DMPQV-APQLVSARSFNS--TALNVTWNPIDQSRERLRGKL 463
G GP ++ ++ + E D+ + P++ S+ T++ V+W P + +RG
Sbjct: 713 TINGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYA 772
Query: 464 IGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
IG+ + + + + Y R + I L P ++Y + + AFN+ GEG
Sbjct: 773 IGYGI---GSPHAQTIKVDYKQR----YYTIENLDPSSHYVITLKAFNNVGEG 818
Score = 71.3 bits (167), Expect = 1e-11
Identities = 59/193 (30%), Positives = 90/193 (46%), Gaps = 20/193 (10%)
Query: 35 LETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIG--AGGKRFITENGNLIIRQL----- 87
++T G +V L C + P P WKKD + + +R + +G+L I +
Sbjct: 60 VDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKH 119
Query: 88 SRDDEGVYTCVAK-NQYGTDESR-GRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADV 144
++ DEG Y CVA GT SR +LIV PRF + P + A N+++ NAD+
Sbjct: 120 NKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNCEVNADL 179
Query: 145 DPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS-AIGR 203
P + W N + L ++ IK+ G L I N + D G Y CVV+S +
Sbjct: 180 VPFV----RWEQNRQPL-----LLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPK 230
Query: 204 ISSHVQLRIEGPP 216
S V+L++ P
Sbjct: 231 YSDEVELKVLPDP 243
Score = 46.4 bits (105), Expect = 3e-04
Identities = 53/209 (25%), Positives = 82/209 (39%), Gaps = 18/209 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP GVQ + ++ + W D N P +T ++ W NIP +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWAD---NSLP-KHQKITDSRYYTVRW---KTNIPANTKY 905
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK-PYEAPANVS- 332
N + + T L P +YEF + G + T+ + P P +V+
Sbjct: 906 KNANATTLSYLVTGLKPNTLYEFSVMVTK--GRRSSTWSMTAHGTTFELVPTSPPKDVTV 963
Query: 333 -GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH- 390
GK + + W P S NG Y I++ + + E +++ +G + H
Sbjct: 964 VSKEGKPKTIIVNWQP--PSEANGKITGYIIYYSTDVN-AEIHDWVIEPV--VGNRLTHQ 1018
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
I TPY K+QA N G GP SE V
Sbjct: 1019 IQELTLDTPYYFKIQARNSKGMGPMSEAV 1047
Score = 45.6 bits (103), Expect = 6e-04
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 470 YWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
++ +E E + S I L P T Y +VMA N G G S T +
Sbjct: 476 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE 535
Query: 530 APQKPPA-SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPI 588
PA ++ +A PT++ V W P + + YK L+ +++ D V
Sbjct: 536 VQLPGPAPNLRAYAASPTSITVTWE--TPVSGNGEIQNYK--LYYMEKGTDKEQDVDVS- 590
Query: 589 EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQ-IGDYHSEA 636
H I+ + Y+ RV+AY+ G G +S+P +A + + D S A
Sbjct: 591 SHSYT--INGLKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAA 636
Score = 43.2 bits (97), Expect = 0.003
Identities = 46/199 (23%), Positives = 79/199 (39%), Gaps = 12/199 (6%)
Query: 428 PQVAPQLVSARSFNSTALNVTW--NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLS 485
P + P V A + + +TW N + + ++ + R WK +
Sbjct: 853 PMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVR---WKTNIPANTKYKNAN 909
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHD- 544
TT ++ L+ GL+P+T Y VM S TF P PP V V + +
Sbjct: 910 ATTLSY-LVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 545 -PTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVP-IEHKLEAYISNIIPG 602
P T+ V W+ P+ + GY + + D + + I P + ++L I +
Sbjct: 969 KPKTIIVNWQ--PPSEANGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLD 1025
Query: 603 KSYNLRVLAYSNGGDGRMS 621
Y ++ A ++ G G MS
Sbjct: 1026 TPYYFKIQARNSKGMGPMS 1044
Score = 33.9 bits (74), Expect = 1.9
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYYYV 505
V W P ++ GK+ G+ + Y N E + + R I L DT YY
Sbjct: 975 VNWQPPSEAN----GKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYF 1030
Query: 506 KVMAFNSAGEGPESERYLERT 526
K+ A NS G GP SE RT
Sbjct: 1031 KIQARNSKGMGPMSEAVQFRT 1051
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1b protein.
Length = 1842
Score = 158 bits (383), Expect = 7e-38
Identities = 158/634 (24%), Positives = 263/634 (41%), Gaps = 41/634 (6%)
Query: 4 CEAKNQLKASYSSAQLRVLSLKPSFKKHPLELE-TYGSEGGNVTLKCKPEAAPKPTFTWK 62
C A N A+ S + ++ + P F P + YG G L C + P P WK
Sbjct: 458 CIASNAA-ATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPPKVMWK 513
Query: 63 --------KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ + G+ I N +L+IR + +D G Y C A N GTD S+ +
Sbjct: 514 HAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLT 573
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A L+C A + PI+ W I +
Sbjct: 574 VKIPAMITSHPNTTIAIKGHAKELNCTARGERPII---IRWEKGDTVIDPDRVMRYAIAT 630
Query: 174 KIDGGEL-TIYNVSLSDVGD---YECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQR 229
K +G E+ + + +D GD + C ++ G +QL ++ PP PP ++I ++
Sbjct: 631 KDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREVKA 689
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
S+ L WT ITG+ + + +S + ++ N+ +A + L
Sbjct: 690 RSMNLRWTQRFDGNSIITGFDIEYKNKSDS--WDFKQSTRNISPTIN-----QANI-VDL 741
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P ++Y R+ + N +G +PS ST P P +V+ + + +TW
Sbjct: 742 HPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPK 800
Query: 350 TSLQNGPGIHYKIFWRRN--GSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
LQNG Y+I +R N GS ++ + +K G+ Y + + + Y V VQAF
Sbjct: 801 KELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYT--LDNLKKFAQYGVVVQAF 858
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
N G GP S + + ED+P P+ V A S S ++W+ + R L G L G+R
Sbjct: 859 NRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWS--EPPRSTLNGVLKGYR 916
Query: 468 LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
+ +W E TTR + G++ T Y V+V+A+ AG+G S +T
Sbjct: 917 VIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTK 976
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVP 587
P PPA + +++ V W + PT + Y + ++
Sbjct: 977 EDVP-GPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETS 1033
Query: 588 IEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
E +L I+++ G+ Y L V A ++ G G S
Sbjct: 1034 PE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1066
Score = 80.2 bits (189), Expect = 2e-14
Identities = 133/555 (23%), Positives = 207/555 (37%), Gaps = 51/555 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + S + + + HP T +G L C W
Sbjct: 554 YLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERPIIIRW 611
Query: 62 KKDNIVIGAGG-KRFIT---ENGNLIIRQLS-----RDDEGVYTCVAKNQYGTDESRGRL 112
+K + VI R+ +NG+ ++ L R D ++C A N YG D +L
Sbjct: 612 EKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQL 671
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
V P PP + ++ V N D + + K+ SD + K+
Sbjct: 672 TVQEPPD-----PPEL--EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQ 724
Query: 173 ----IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE----GPPGPPGGVQI 224
I + I ++ + V + IGR +L I P GPP V +
Sbjct: 725 STRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTL 784
Query: 225 LGIQRSSVTLEWTDSNS---NGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
+ S+ + W NG I GY + R NS S +++E+ + G
Sbjct: 785 QPVTSQSIQVTWKAPKKELQNG-VIRGYQIGYRE--NSPG---SNGQYSIVEM-KATGDS 837
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
L +A Y +QA N G G PS+ +T D P + P NV +
Sbjct: 838 EVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPPENVRALSITSDVA 896
Query: 342 TITWTPLPTSLQNGPGIHYK-IFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
I+W+ P S NG Y+ IFW +G E Q++ + V + +T
Sbjct: 897 VISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER------VELRGMEKFT 950
Query: 399 PYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y V+V A+ G G S V+ I + ED+P P + A +++++ V+W P +
Sbjct: 951 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVVSWLPPTKPNGV 1009
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+R I Q E Y + + + I L Y + V A SAG G
Sbjct: 1010 IRKYTIFCSSPGSGQPAPSE----YETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1065
Query: 519 SERYLERTFRKAPQK 533
SE+ KAP K
Sbjct: 1066 SEKVTIEPAGKAPAK 1080
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER- 458
Y +++ +FN IG S+ +TI + E P P V+ + S ++ VTW + +
Sbjct: 747 YSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 806
Query: 459 -LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+RG IG+R + N + + + + L+ Y V V AFN AG GP
Sbjct: 807 VIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGP 865
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
S T P +PP +V + + W + L GY+V W L D
Sbjct: 866 SSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVD 925
Query: 578 MSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
I ++E + + +Y+++VLAY+ GDG SS
Sbjct: 926 GEWGEMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSS 969
Score = 56.0 bits (129), Expect = 4e-07
Identities = 52/220 (23%), Positives = 97/220 (44%), Gaps = 15/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
+Y+C A+N + ++ A++ V PS + + + G TL C+ P +
Sbjct: 271 VYRCTARNLVGSAEYQARINVRG-PPSIRA----MRNITAVAGRDTLINCRVIGYPYYSI 325
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD +++ ++ + ENG L + + + DEG Y C Q S+ + ++ P
Sbjct: 326 KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 385
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
++ + PP Q+ + + + D+ PI T W +G I S + + + +
Sbjct: 386 PLIQPFEFPPASIGQLLYIPCVVSSGDM-PIRIT---WRKDGQVIISGSGVTIESKEFMS 441
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VSL G+ C+ +A +S QL + PP
Sbjct: 442 S--LQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPP 479
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
+V L C P P W KD+ I + G R I NG L++R + +D G YTC A
Sbjct: 1095 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1154
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRIT---AQVNSVVFLHCNADVDPILDTAYLWNH 156
N G D L+V P PR+T +S+ D ++ +
Sbjct: 1155 TNTGGFDTIIVNLLVQVPPD-----QPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1209
Query: 157 NGLRIKDSSDLYVN---KRIKIDGGEL-TIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ ++ D++++ + K+D + T Y V L+ GRIS ++ +
Sbjct: 1210 SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSV------GSGRISEIIEAKT 1263
Query: 213 EG--PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
G P I + L N+ G PIT +L R W + N
Sbjct: 1264 HGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSG 1323
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ + + AT W YE R++A N G G +A QF+T
Sbjct: 1324 EVFLTEL---REAT-------W--YELRMRACNSAGCGNETA---QFAT 1357
Score = 48.4 bits (110), Expect = 8e-05
Identities = 37/152 (24%), Positives = 58/152 (38%), Gaps = 7/152 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQY 103
++ L C P P W KD + A R+ L I L +D G Y C N +
Sbjct: 31 SLQLPCTAPGYPIPAIRWLKDGRPLPADS-RWTKRITGLTISDLRTEDSGTYICEVTNTF 89
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKD 163
G+ E+ G L+V+ P + P ++ + S V L C P + W N +
Sbjct: 90 GSAEATGILMVI-DPLHVTLTPKKLKTGIGSTVILSCALTGSP--EFTIRWYRNTELVLP 146
Query: 164 SSDLYVNKRIKIDGGELTIYNVSLSDVGDYEC 195
+ + + L I + S G Y+C
Sbjct: 147 DEAISIR---GLSNETLLITSAQKSHSGAYQC 175
Score = 45.2 bits (102), Expect = 8e-04
Identities = 57/222 (25%), Positives = 87/222 (39%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT-FT 60
Y C Q + S S + + + P + P E S G + + C + P T
Sbjct: 362 YLCSVLIQPQLSISQSVHVAVKVPPLIQ--PFEFPP-ASIGQLLYIPCVVSSGDMPIRIT 418
Query: 61 WKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD VI +G I +L I +S G TC+A N T +LIV
Sbjct: 419 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVP 478
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH--NGLRIKDSSDLYVNKRIKI 175
PRF+ + P L+C+ D P +W H + + + RI+I
Sbjct: 479 PRFVVQ-PNNQDGIYGKAGVLNCSVDGYP--PPKVMWKHAKGSGNPQQYHPVPLTGRIQI 535
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
L I +V D+G Y C + +G IS + L ++ P
Sbjct: 536 LPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 577
Score = 43.2 bits (97), Expect = 0.003
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CE N ++ ++ L V+ P +L+T G V L C +P+ T W
Sbjct: 81 YICEVTNTFGSAEATGILMVID-PLHVTLTPKKLKT--GIGSTVILSCALTGSPEFTIRW 137
Query: 62 KKDNIVIGAGGKRFIT--ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR--A 117
++ ++ I N L+I + G Y C A + T + +I L
Sbjct: 138 YRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFA-IIALEDGT 196
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PR + ++ L C A P + + + ++D S N+ DG
Sbjct: 197 PRIVSSFSEKVV-NPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHR-TNQYTMSDG 253
Query: 178 GELTIYNVS---LSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ NV+ + D G Y C ++ +G ++ + GPP
Sbjct: 254 TTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 295
Score = 40.7 bits (91), Expect = 0.016
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 427 MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSR 486
+P P+L +++ +++++ +TW P D +RG ++ + + +N EE ++S
Sbjct: 1171 VPPDQPRLTVSKT-SASSITLTWIPGDNGGSSIRGFVLQYSV-----DNSEEWKDVFISS 1224
Query: 487 TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ R++ L L+ T+Y VK+ A NS G G SE +T + P
Sbjct: 1225 SERSFKLD-SLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREP 1268
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1a protein.
Length = 2053
Score = 158 bits (383), Expect = 7e-38
Identities = 158/634 (24%), Positives = 263/634 (41%), Gaps = 41/634 (6%)
Query: 4 CEAKNQLKASYSSAQLRVLSLKPSFKKHPLELE-TYGSEGGNVTLKCKPEAAPKPTFTWK 62
C A N A+ S + ++ + P F P + YG G L C + P P WK
Sbjct: 669 CIASNAA-ATVSRERQLIVRVPPRFVVQPNNQDGIYGKAG---VLNCSVDGYPPPKVMWK 724
Query: 63 --------KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ + G+ I N +L+IR + +D G Y C A N GTD S+ +
Sbjct: 725 HAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLT 784
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A L+C A + PI+ W I +
Sbjct: 785 VKIPAMITSHPNTTIAIKGHAKELNCTARGERPII---IRWEKGDTVIDPDRVMRYAIAT 841
Query: 174 KIDGGEL-TIYNVSLSDVGD---YECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQR 229
K +G E+ + + +D GD + C ++ G +QL ++ PP PP ++I ++
Sbjct: 842 KDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREVKA 900
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
S+ L WT ITG+ + + +S + ++ N+ +A + L
Sbjct: 901 RSMNLRWTQRFDGNSIITGFDIEYKNKSDS--WDFKQSTRNISPTIN-----QANI-VDL 952
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
P ++Y R+ + N +G +PS ST P P +V+ + + +TW
Sbjct: 953 HPASVYSIRMYSFNKIGRSEPSKELT-ISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPK 1011
Query: 350 TSLQNGPGIHYKIFWRRN--GSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
LQNG Y+I +R N GS ++ + +K G+ Y + + + Y V VQAF
Sbjct: 1012 KELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYT--LDNLKKFAQYGVVVQAF 1069
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
N G GP S + + ED+P P+ V A S S ++W+ + R L G L G+R
Sbjct: 1070 NRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWS--EPPRSTLNGVLKGYR 1127
Query: 468 LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
+ +W E TTR + G++ T Y V+V+A+ AG+G S +T
Sbjct: 1128 VIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTK 1187
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVP 587
P PPA + +++ V W + PT + Y + ++
Sbjct: 1188 EDVP-GPPAGIKAVPSSASSVVVSW--LPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETS 1244
Query: 588 IEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
E +L I+++ G+ Y L V A ++ G G S
Sbjct: 1245 PE-QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS 1277
Score = 80.2 bits (189), Expect = 2e-14
Identities = 133/555 (23%), Positives = 207/555 (37%), Gaps = 51/555 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + S + + + HP T +G L C W
Sbjct: 765 YLCQASNGVGTDISKSMFLTVKIPAMITSHPNT--TIAIKGHAKELNCTARGERPIIIRW 822
Query: 62 KKDNIVIGAGG-KRFIT---ENGNLIIRQLS-----RDDEGVYTCVAKNQYGTDESRGRL 112
+K + VI R+ +NG+ ++ L R D ++C A N YG D +L
Sbjct: 823 EKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQL 882
Query: 113 IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
V P PP + ++ V N D + + K+ SD + K+
Sbjct: 883 TVQEPPD-----PPEL--EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQ 935
Query: 173 ----IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE----GPPGPPGGVQI 224
I + I ++ + V + IGR +L I P GPP V +
Sbjct: 936 STRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTL 995
Query: 225 LGIQRSSVTLEWTDSNS---NGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
+ S+ + W NG I GY + R NS S +++E+ + G
Sbjct: 996 QPVTSQSIQVTWKAPKKELQNG-VIRGYQIGYRE--NSPG---SNGQYSIVEM-KATGDS 1048
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
L +A Y +QA N G G PS+ +T D P + P NV +
Sbjct: 1049 EVYTLDNLKKFAQYGVVVQAFNRAGTG-PSSSEINATTLEDVPSQPPENVRALSITSDVA 1107
Query: 342 TITWTPLPTSLQNGPGIHYK-IFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
I+W+ P S NG Y+ IFW +G E Q++ + V + +T
Sbjct: 1108 VISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER------VELRGMEKFT 1161
Query: 399 PYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y V+V A+ G G S V+ I + ED+P P + A +++++ V+W P +
Sbjct: 1162 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPG-PPAGIKAVPSSASSVVVSWLPPTKPNGV 1220
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+R I Q E Y + + + I L Y + V A SAG G
Sbjct: 1221 IRKYTIFCSSPGSGQPAPSE----YETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1276
Query: 519 SERYLERTFRKAPQK 533
SE+ KAP K
Sbjct: 1277 SEKVTIEPAGKAPAK 1291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 59/226 (26%), Positives = 95/226 (42%), Gaps = 6/226 (2%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER- 458
Y +++ +FN IG S+ +TI + E P P V+ + S ++ VTW + +
Sbjct: 958 YSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNG 1017
Query: 459 -LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+RG IG+R + N + + + + L+ Y V V AFN AG GP
Sbjct: 1018 VIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGP 1076
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
S T P +PP +V + + W + L GY+V W L D
Sbjct: 1077 SSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVD 1136
Query: 578 MSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
I ++E + + +Y+++VLAY+ GDG SS
Sbjct: 1137 GEWGEMQNITTTRERVE--LRGMEKFTNYSVQVLAYTQAGDGVRSS 1180
Score = 56.0 bits (129), Expect = 4e-07
Identities = 52/220 (23%), Positives = 97/220 (44%), Gaps = 15/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTL-KCKPEAAPKPTF 59
+Y+C A+N + ++ A++ V PS + + + G TL C+ P +
Sbjct: 482 VYRCTARNLVGSAEYQARINVRG-PPSIRA----MRNITAVAGRDTLINCRVIGYPYYSI 536
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD +++ ++ + ENG L + + + DEG Y C Q S+ + ++ P
Sbjct: 537 KWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVP 596
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
++ + PP Q+ + + + D+ PI T W +G I S + + + +
Sbjct: 597 PLIQPFEFPPASIGQLLYIPCVVSSGDM-PIRIT---WRKDGQVIISGSGVTIESKEFMS 652
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VSL G+ C+ +A +S QL + PP
Sbjct: 653 S--LQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPP 690
Score = 54.8 bits (126), Expect = 9e-07
Identities = 47/198 (23%), Positives = 75/198 (37%), Gaps = 11/198 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE----GGNVTLKCKPEAAPKP 57
Y+C K++ + LS+ + P L+ + S+ G V L C P P
Sbjct: 196 YRCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIP 255
Query: 58 TFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W KD + A R+ L I L +D G Y C N +G+ E+ G L+V+
Sbjct: 256 AIRWLKDGRPLPADS-RWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVI-D 313
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P + P ++ + S V L C P + W N + + + +
Sbjct: 314 PLHVTLTPKKLKTGIGSTVILSCALTGSP--EFTIRWYRNTELVLPDEAISIR---GLSN 368
Query: 178 GELTIYNVSLSDVGDYEC 195
L I + S G Y+C
Sbjct: 369 ETLLITSAQKSHSGAYQC 386
Score = 52.0 bits (119), Expect = 7e-06
Identities = 71/289 (24%), Positives = 110/289 (38%), Gaps = 39/289 (13%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
+V L C P P W KD+ I + G R I NG L++R + +D G YTC A
Sbjct: 1306 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1365
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRIT---AQVNSVVFLHCNADVDPILDTAYLWNH 156
N G D L+V P PR+T +S+ D ++ +
Sbjct: 1366 TNTGGFDTIIVNLLVQVPPD-----QPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQY 1420
Query: 157 NGLRIKDSSDLYVN---KRIKIDGGEL-TIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ ++ D++++ + K+D + T Y V L+ GRIS ++ +
Sbjct: 1421 SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSV------GSGRISEIIEAKT 1474
Query: 213 EG--PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
G P I + L N+ G PIT +L R W + N
Sbjct: 1475 HGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANSSG 1534
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ + + AT W YE R++A N G G +A QF+T
Sbjct: 1535 EVFLTEL---REAT-------W--YELRMRACNSAGCGNETA---QFAT 1568
Score = 45.2 bits (102), Expect = 8e-04
Identities = 61/213 (28%), Positives = 91/213 (42%), Gaps = 24/213 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTL-KCK-PEAAPK-- 56
Y C A+N S +RV K F++ + + +E S GNV + KC P +
Sbjct: 101 YFCTAENAA-GKIRSPNIRV---KAVFREPYTVRVEDQRSMRGNVAVFKCLIPFLGQEYV 156
Query: 57 PTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDE-GVYTCVAKNQYG--TDESRG-RL 112
+W+KD + I + FIT +G L I + ++D Y C+ K++Y T +S G RL
Sbjct: 157 SVVSWEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARL 216
Query: 113 IVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
V + + +Q V L C A PI A W +G + +D
Sbjct: 217 SVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPI--PAIRWLKDGRPL--PADSRW 272
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
KRI LTI ++ D G Y C V + G
Sbjct: 273 TKRIT----GLTISDLRTEDSGTYICEVTNTFG 301
Score = 45.2 bits (102), Expect = 8e-04
Identities = 57/222 (25%), Positives = 87/222 (39%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT-FT 60
Y C Q + S S + + + P + P E S G + + C + P T
Sbjct: 573 YLCSVLIQPQLSISQSVHVAVKVPPLIQ--PFEFPP-ASIGQLLYIPCVVSSGDMPIRIT 629
Query: 61 WKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD VI +G I +L I +S G TC+A N T +LIV
Sbjct: 630 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVP 689
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH--NGLRIKDSSDLYVNKRIKI 175
PRF+ + P L+C+ D P +W H + + + RI+I
Sbjct: 690 PRFVVQ-PNNQDGIYGKAGVLNCSVDGYP--PPKVMWKHAKGSGNPQQYHPVPLTGRIQI 746
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
L I +V D+G Y C + +G IS + L ++ P
Sbjct: 747 LPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 788
Score = 44.0 bits (99), Expect = 0.002
Identities = 48/222 (21%), Positives = 85/222 (38%), Gaps = 14/222 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CE N ++ ++ L V+ P +L+T G V L C +P+ T W
Sbjct: 292 YICEVTNTFGSAEATGILMVID-PLHVTLTPKKLKT--GIGSTVILSCALTGSPEFTIRW 348
Query: 62 KKDNIVIGAGGKRFIT--ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR--A 117
++ ++ I N L+I + G Y C A + T + +I L
Sbjct: 349 YRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFA-IIALEDGT 407
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PR + ++ L C A P + + + ++D S N+ DG
Sbjct: 408 PRIVSSFSEKVV-NPGEQFSLMCAAKGAPPPTVTWALDDEPI-VRDGSHR-TNQYTMSDG 464
Query: 178 GELTIYNVS---LSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ NV+ + D G Y C ++ +G ++ + GPP
Sbjct: 465 TTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Score = 40.7 bits (91), Expect = 0.016
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 7/105 (6%)
Query: 427 MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSR 486
+P P+L +++ +++++ +TW P D +RG ++ + + +N EE ++S
Sbjct: 1382 VPPDQPRLTVSKT-SASSITLTWIPGDNGGSSIRGFVLQYSV-----DNSEEWKDVFISS 1435
Query: 487 TTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAP 531
+ R++ L L+ T+Y VK+ A NS G G SE +T + P
Sbjct: 1436 SERSFKLD-SLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREP 1479
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 149 bits (360), Expect = 4e-35
Identities = 159/640 (24%), Positives = 260/640 (40%), Gaps = 65/640 (10%)
Query: 1 MYQCEAKNQLKA-SYSSAQLRVLSLKPSFKKHPLELETYGS----EGGNVTLKCKPEAAP 55
+Y+C A+N + + + A++R+LS P + L+ + EG + L+C P
Sbjct: 209 IYRCSARNPASSRTGNEAEVRILS-DPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYP 267
Query: 56 KPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P+FTW + VI K++ G NL+I ++ DD G+YTCV + + L V
Sbjct: 268 PPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV 327
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L P FL P + A + + C P+ W NG + S +
Sbjct: 328 LVPPWFLNH-PSNLYAYESMDIEFECTVSGKPV--PTVNWMKNGDVVIPSDYFQI----- 379
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP--------PGPPGGVQILG 226
+ G L I V SD G Y+CV ++ G + QL + P P P V +
Sbjct: 380 VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL 439
Query: 227 IQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATV 285
+ V L W + + G T + R N E N + G + TV
Sbjct: 440 VSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNR------ERALNTTQP----GSLQLTV 489
Query: 286 STTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-NVSGGGGKTGDLTIT 344
L P A+Y FR+ A N GPG+ S P + +T + P N+ + IT
Sbjct: 490 GN-LKPEAMYTFRVVAYNEWGPGESSQPI-KVATQPELQVPGPVENLQAVSTSPTSILIT 547
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P + NGP Y++F + E Q++ + + +T Y ++
Sbjct: 548 WEP--PAYANGPVQGYRLFCTEVSTGKE-QNI------EVDGLSYKLEGLKKFTEYSLRF 598
Query: 405 QAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI 464
A+N GPG ++ +T+ + D+P PQ VS NS ++ V+W P + G +
Sbjct: 599 LAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQ--NGFIT 656
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
G+++++ K + E W L GL+ + Y +V A G GP S Y
Sbjct: 657 GYKIRHRKTTRRGE---METLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTA 713
Query: 525 RTFRK---APQKP--PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMS 579
T Q P P+S++V P T ++ + P N + GY + +
Sbjct: 714 ETPENDLDESQVPDQPSSLHV---RPQTNCIIMSWTPPLNPNIVVRGYII-----GYGVG 765
Query: 580 TANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
+ V ++ K Y I + Y + + A++N G+G
Sbjct: 766 SPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEG 805
Score = 100 bits (239), Expect = 2e-20
Identities = 150/638 (23%), Positives = 258/638 (40%), Gaps = 58/638 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQCEA S S +V P E T G V LKC+ P PT
Sbjct: 114 LYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVT-AFMGDTVLLKCEVIGEPMPTIH 172
Query: 61 WKK---DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT---DESRGRLI- 113
W+K D I + + +G L I +L D G+Y C A+N + +E+ R++
Sbjct: 173 WQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILS 232
Query: 114 ---VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
+ R FL++ P + A L C P ++ W LR ++ L
Sbjct: 233 DPGLHRQLYFLQR-PSNVVAIEGKDAVLECCVSGYP--PPSFTW----LRGEEVIQLRSK 285
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
K + G L I NV+ D G Y CVV IS+ +L + PP L
Sbjct: 286 KYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNL-YAYE 344
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
S+ +E+ + +G+P+ +W V+ IP+ G +
Sbjct: 345 SMDIEF-ECTVSGKPVP------TVNWMKNGDVV---IPSDY-FQIVGGSNLRILGVVKS 393
Query: 291 PWAIYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
Y+ A N G Q SA P P +S P AP +V + + ++W
Sbjct: 394 DEGFYQ--CVAENEAGNAQTSAQLIVPKPAIPSSSVLP-SAPRDVVPVLVSSRFVRLSWR 450
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P + G + +F+ R G E ++L + G++ V ++ YT +V A
Sbjct: 451 P-PAEAK-GNIQTFTVFFSREGDNRE-RALNTTQPGSLQLTVGNLKPEAMYT---FRVVA 504
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAP-QLVSARSFNSTALNVTWNPIDQSRERLRG-KLI 464
+N+ GPG S+ + + + ++ P + + A S + T++ +TW P + ++G +L
Sbjct: 505 YNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLF 564
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
+ K++N E + + Y + GL+ T Y ++ +A+N G G ++
Sbjct: 565 CTEVSTGKEQNIEVDGLSY---------KLEGLKKFTEYSLRFLAYNRYGPGVSTDDITV 615
Query: 525 RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDT 584
T P PP +V++ + +++V W + + GYK+R +T
Sbjct: 616 VTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIR--HRKTTRRGEMET 673
Query: 585 IVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
+ P + L + + G Y+ +V A + G G S+
Sbjct: 674 LEP--NNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
Score = 64.5 bits (150), Expect = 1e-09
Identities = 59/210 (28%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 42 GGNVTLKCKPEA-APKPTFTWKKDNI--VIGAGGKRFITENGNLIIRQL-----SRDDEG 93
GGNV L C E+ P WKKD I +G ++ NG+L+I+ + + DEG
Sbjct: 54 GGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEG 113
Query: 94 VYTCVAK-NQYGTDESRGRLIVLRAP-RFLEKLPPRITAQVNSVVFLHCNADVDPILDTA 151
+Y C A G+ SR + + P RFL + +TA + V L C +P + T
Sbjct: 114 LYQCEASLGDSGSIISRTAKVAVAGPLRFLSQ-TESVTAFMGDTVLLKCEVIGEP-MPTI 171
Query: 152 YLWNHNGLRIKDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYECVVKS-AIGRISSHVQ 209
+ W N +D + + + R+ + G L I + D+G Y C ++ A R + +
Sbjct: 172 H-WQKNQ---QDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAE 227
Query: 210 LRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
+RI PG + L + V +E D+
Sbjct: 228 VRILSDPGLHRQLYFLQRPSNVVAIEGKDA 257
Score = 41.5 bits (93), Expect = 0.009
Identities = 46/207 (22%), Positives = 87/207 (42%), Gaps = 20/207 (9%)
Query: 430 VAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTR 489
V P LVS+R + ++W P +++ ++ + ++ +E E ++
Sbjct: 435 VVPVLVSSRF-----VRLSWRPPAEAKGNIQTFTV-----FFSREGDNRERALNTTQPGS 484
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWA--HDPTT 547
+ L+P+ Y +V+A+N G G ES + ++ + Q P N+ A PT+
Sbjct: 485 LQLTVGNLKPEAMYTFRVVAYNEWGPG-ESSQPIKVATQPELQVPGPVENLQAVSTSPTS 543
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNL 607
+ + W P P+ GY++ E+ N + + +KLE + Y+L
Sbjct: 544 ILITWE--PPAYANGPVQGYRLFCTEVSTGKEQ-NIEVDGLSYKLEG----LKKFTEYSL 596
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
R LAY+ G G + + D S
Sbjct: 597 RFLAYNRYGPGVSTDDITVVTLSDVPS 623
Score = 37.1 bits (82), Expect = 0.20
Identities = 33/107 (30%), Positives = 48/107 (44%), Gaps = 7/107 (6%)
Query: 425 EDMPQVAPQ--LVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE-EECI 481
E P AP+ V R A+ V+W P ++ GK+ + L Y +N ++ I
Sbjct: 941 EAAPTSAPKDFTVITREGKPRAVIVSWQPPLEAN----GKITAYILFYTLDKNIPIDDWI 996
Query: 482 YYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
R I+ L DT YY ++ A NS G GP S+ L RT +
Sbjct: 997 METISGDRLTHQIMDLNLDTMYYFRIQARNSKGVGPLSDPILFRTLK 1043
Score = 36.3 bits (80), Expect = 0.35
Identities = 42/201 (20%), Positives = 77/201 (38%), Gaps = 8/201 (3%)
Query: 428 PQVAPQLVSARSFNSTALNVTW--NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLS 485
P + P V A + A+ V+W N + ++++ +L R W+ + Y
Sbjct: 843 PMLPPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVR---WRT-SFSASAKYKSE 898
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDP 545
TT GL+P+T Y VM + S T+ AP P V +
Sbjct: 899 DTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDFTVITREG 958
Query: 546 TTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE-HKLEAYISNIIPGKS 604
V+ + P + Y + + LD+++ + + I +L I ++
Sbjct: 959 KPRAVIVSWQPPLEANGKITAY-ILFYTLDKNIPIDDWIMETISGDRLTHQIMDLNLDTM 1017
Query: 605 YNLRVLAYSNGGDGRMSSPTI 625
Y R+ A ++ G G +S P +
Sbjct: 1018 YYFRIQARNSKGVGPLSDPIL 1038
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 147 bits (355), Expect = 2e-34
Identities = 72/216 (33%), Positives = 118/216 (54%), Gaps = 3/216 (1%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MYQC A+N A Y++A+L++L+L P+F+ +P++ + ++GG V ++CKP+AAPKP F+
Sbjct: 388 MYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFS 447
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W K + + I E+G+L I ++R+D G+YTC A+N G S G L++ R
Sbjct: 448 WSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 507
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK-DSSDLYVNKRIKID-GG 178
+ P V + C A DP LD ++W+ NG I + +++ + +D G
Sbjct: 508 I-LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNG 566
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
EL I N L G Y C ++ + S+ L + G
Sbjct: 567 ELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/178 (28%), Positives = 76/178 (42%), Gaps = 7/178 (3%)
Query: 26 PSFKKHPLELETYGSEG--GNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI 83
P F++ P+ Y E G V+L C+ A+P P + W+ +N + R+ GNL+
Sbjct: 41 PIFEEQPINT-IYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
Query: 84 IRQLSRD-DEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
I + D G+Y C+A N YG S L F + P + + + L C+
Sbjct: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
D +Y W N + + D + + G L I NV SD G+Y C V S
Sbjct: 160 PPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
Score = 65.3 bits (152), Expect = 7e-10
Identities = 48/178 (26%), Positives = 83/178 (46%), Gaps = 20/178 (11%)
Query: 36 ETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGV 94
+ Y G NVTL+C P P W+K ++ I+ +G ++ I + +DEG+
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGI 307
Query: 95 YTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
Y C A+N G D+ + R+ V P ++E + + S ++ C A PI W
Sbjct: 308 YECEAENIRGKDKHQARIYVQAFPEWVEHIND-TEVDIGSDLYWPCVATGKPI--PTIRW 364
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
NG Y + GEL +Y+V+ + G Y+C+ ++ G I ++ +L+I
Sbjct: 365 LKNG---------YAYHK-----GELRLYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 59.3 bits (137), Expect = 4e-08
Identities = 55/218 (25%), Positives = 94/218 (43%), Gaps = 23/218 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+CEA+N A++ V + P + +H + E G ++ C P PT
Sbjct: 307 IYECEAENIRGKDKHQARIYVQAF-PEWVEHINDTEV--DIGSDLYWPCVATGKPIPTIR 363
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR-APR 119
W K+ + G L + ++ ++ G+Y C+A+N YG + L +L AP
Sbjct: 364 WLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPT 414
Query: 120 F-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DG 177
F + + +I A V + C P + W+ K + L + RI I +
Sbjct: 415 FEMNPMKKKILAAKGGRVIIECKPKAAP--KPKFSWS------KGTEWLVNSSRILIWED 466
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
G L I N++ +D G Y C ++ G+ +S L I P
Sbjct: 467 GSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDP 504
Score = 44.4 bits (100), Expect = 0.001
Identities = 47/190 (24%), Positives = 76/190 (40%), Gaps = 22/190 (11%)
Query: 41 EGGNVTLKCKP--EAAPKPTFTWKKDN--IVIGAGGKRFITE-NGNLIIRQLSRDDEGVY 95
EG + L C P ++ W + + I +RF+++ NGNL I + D+G Y
Sbjct: 150 EGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNY 209
Query: 96 TCVAKNQYGTDESRGRLI-VLRAP-RFLEKLPPRITAQVNSV-------VFLHCNADVDP 146
+C + T + I ++ P R + P I Q V V L C A +P
Sbjct: 210 SCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNP 269
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ D W K + I G L I+N+ L D G YEC ++ G+
Sbjct: 270 VPDIR--WR------KVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKH 321
Query: 207 HVQLRIEGPP 216
++ ++ P
Sbjct: 322 QARIYVQAFP 331
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 145 bits (351), Expect = 5e-34
Identities = 101/359 (28%), Positives = 153/359 (42%), Gaps = 18/359 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A N+ ++A + VL+ P P L C +P PT
Sbjct: 423 VYQCNASNEYGYLLANAFVNVLAEPPRILT-PANTLYQVIANRPALLDCAFFGSPLPTIE 481
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ ENG L I +D G YTCVA+N+ G ++ L + A
Sbjct: 482 WFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDAT- 540
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
++ K P Q S+V C D L LW +KD+ +L ++R +D
Sbjct: 541 WIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRELPSDERFTVDKDH 594
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L + +VS D G Y CV + + +S+ L + P PP +++ SV L WT
Sbjct: 595 LVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPG 654
Query: 240 NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRI 299
+ N PIT +++ Y + + P + + T L P+ Y FR+
Sbjct: 655 DDNNSPITKFIIE---------YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRV 705
Query: 300 QAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
A+N +G PS S Q+ T +P + P V G G + +L ITW PL NGPG+
Sbjct: 706 MAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGL 764
Score = 58.8 bits (136), Expect = 6e-08
Identities = 56/215 (26%), Positives = 81/215 (37%), Gaps = 12/215 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC AKN L A + + +RV + P + P L E G TL C+ PKP +W
Sbjct: 332 YQCIAKNALGAIHHTISVRVKAA-PYWITAPQNLVLSPGEDG--TLICRANGNPKPRISW 388
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAP 118
+ I I + +I + VY C A N+YG + + VL P
Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R L N L C P+ + G + + D+YV + G
Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE--DIYVLH----ENG 502
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
L I G Y CV ++ +G + V L I+
Sbjct: 503 TLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIK 537
Score = 52.0 bits (119), Expect = 7e-06
Identities = 44/175 (25%), Positives = 71/175 (40%), Gaps = 7/175 (4%)
Query: 43 GNV-TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GNV +L+C E P P W K++ ++ + L I +S D G Y C+AKN
Sbjct: 279 GNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKN 338
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G + V AP ++ P + L C A+ +P W NG+ I
Sbjct: 339 ALGAIHHTISVRVKAAPYWI-TAPQNLVLSPGEDGTLICRANGNP--KPRISWLTNGVPI 395
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + D + KIDG + NV Y+C + G + ++ + + P
Sbjct: 396 EIAPD---DPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEP 447
Score = 45.2 bits (102), Expect = 8e-04
Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 16/165 (9%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLIIRQLSRDD----EGVYT 96
N+ ++C+ + P P+F+W ++ +T G LII +S EGVY
Sbjct: 57 NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQ 116
Query: 97 CVAKNQYGTDESRGRLI-VLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N+ G S ++ R+P + EKL P IT Q + L C + + W
Sbjct: 117 CTARNERGAAVSNNIVVRPSRSPLWTKEKLEP-ITLQSGQSLVLPCRPPIG-LPPPIIFW 174
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDV-GDYECVVK 198
N + S+ V++ + G+L NV D DY C +
Sbjct: 175 MDNSFQRLPQSE-RVSQGL---NGDLYFSNVLPEDTREDYICYAR 215
Score = 34.3 bits (75), Expect = 1.4
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQC A+N+ A+ S+ + S P + K LE T S G ++ L C+P P
Sbjct: 114 VYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS-GQSLVLPCRPPIGLPPPII 172
Query: 61 WKKDNIVIGAGGKRFITE--NGNLIIRQ-LSRDDEGVYTCVAK 100
+ DN +++ NG+L L D Y C A+
Sbjct: 173 FWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 215
Score = 33.1 bits (72), Expect = 3.3
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 497 LQPDTYYYVKVMAFNSAGE---GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWR 553
L P Y +VMA NS G+ SE+YL T P K P +V +P L + W+
Sbjct: 695 LSPYVNYSFRVMAVNSIGKSLPSEASEQYL--TKASEPDKNPTAVEGLGSEPDNLVITWK 752
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 144 bits (348), Expect = 1e-33
Identities = 158/640 (24%), Positives = 259/640 (40%), Gaps = 65/640 (10%)
Query: 1 MYQCEAKNQLKA-SYSSAQLRVLSLKPSFKKHPLELETYGS----EGGNVTLKCKPEAAP 55
+Y+C A+N + + + A++R+LS P + L+ + EG + L+ P
Sbjct: 143 IYRCSARNPASSRTGNEAEVRILS-DPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYP 201
Query: 56 KPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P+FTW + VI K++ G NL+I ++ DD G+YTCV + + L V
Sbjct: 202 PPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV 261
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L P FL P + A + + C P+ W NG + S +
Sbjct: 262 LVPPWFLNH-PSNLYAYESMDIEFECTVSGKPV--PTVNWMKNGDVVIPSDYFQI----- 313
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP--------PGPPGGVQILG 226
+ G L I V SD G Y+CV ++ G + QL + P P P V +
Sbjct: 314 VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL 373
Query: 227 IQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATV 285
+ V L W + + G T + R N E N + G + TV
Sbjct: 374 VSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNR------ERALNTTQP----GSLQLTV 423
Query: 286 STTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-NVSGGGGKTGDLTIT 344
L P A+Y FR+ A N GPG+ S P + +T + P N+ + IT
Sbjct: 424 GN-LKPEAMYTFRVVAYNEWGPGESSQPI-KVATQPELQVPGPVENLQAVSTSPTSILIT 481
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P + NGP Y++F + E Q++ + + +T Y ++
Sbjct: 482 WEP--PAYANGPVQGYRLFCTEVSTGKE-QNI------EVDGLSYKLEGLKKFTEYSLRF 532
Query: 405 QAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI 464
A+N GPG ++ +T+ + D+P PQ VS NS ++ V+W P + G +
Sbjct: 533 LAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQ--NGFIT 590
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
G+++++ K + E W L GL+ + Y +V A G GP S Y
Sbjct: 591 GYKIRHRKTTRRGE---METLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTA 647
Query: 525 RTFRK---APQKP--PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMS 579
T Q P P+S++V P T ++ + P N + GY + +
Sbjct: 648 ETPENDLDESQVPDQPSSLHV---RPQTNCIIMSWTPPLNPNIVVRGYII-----GYGVG 699
Query: 580 TANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
+ V ++ K Y I + Y + + A++N G+G
Sbjct: 700 SPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEG 739
Score = 99.1 bits (236), Expect = 4e-20
Identities = 148/638 (23%), Positives = 258/638 (40%), Gaps = 58/638 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQCEA S S +V P E T G V LKC+ P PT
Sbjct: 48 LYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVT-AFMGDTVLLKCEVIGEPMPTIH 106
Query: 61 WKK---DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT---DESRGRLI- 113
W+K D I + + +G L I +L D G+Y C A+N + +E+ R++
Sbjct: 107 WQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILS 166
Query: 114 ---VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
+ R FL++ + + V C + P ++ W LR ++ L
Sbjct: 167 DPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPP---PSFTW----LRGEEVIQLRSK 219
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
K + G L I NV+ D G Y CVV IS+ +L + PP L
Sbjct: 220 KYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNL-YAYE 278
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
S+ +E+ + +G+P+ +W V+ IP+ G +
Sbjct: 279 SMDIEF-ECTVSGKPVP------TVNWMKNGDVV---IPSDY-FQIVGGSNLRILGVVKS 327
Query: 291 PWAIYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
Y+ A N G Q SA P P +S P AP +V + + ++W
Sbjct: 328 DEGFYQ--CVAENEAGNAQTSAQLIVPKPAIPSSSVLP-SAPRDVVPVLVSSRFVRLSWR 384
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P + G + +F+ R G E ++L + G++ V ++ YT +V A
Sbjct: 385 P-PAEAK-GNIQTFTVFFSREGDNRE-RALNTTQPGSLQLTVGNLKPEAMYT---FRVVA 438
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAP-QLVSARSFNSTALNVTWNPIDQSRERLRG-KLI 464
+N+ GPG S+ + + + ++ P + + A S + T++ +TW P + ++G +L
Sbjct: 439 YNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLF 498
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
+ K++N E + + Y + GL+ T Y ++ +A+N G G ++
Sbjct: 499 CTEVSTGKEQNIEVDGLSY---------KLEGLKKFTEYSLRFLAYNRYGPGVSTDDITV 549
Query: 525 RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDT 584
T P PP +V++ + +++V W + + GYK+R +T
Sbjct: 550 VTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIR--HRKTTRRGEMET 607
Query: 585 IVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
+ P + L + + G Y+ +V A + G G S+
Sbjct: 608 LEP--NNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 643
Score = 57.2 bits (132), Expect = 2e-07
Identities = 55/204 (26%), Positives = 92/204 (45%), Gaps = 18/204 (8%)
Query: 57 PTFTWKKDNI--VIGAGGKRFITENGNLIIRQL-----SRDDEGVYTCVAK-NQYGTDES 108
P WKKD I +G ++ NG+L+I+ + + DEG+Y C A G+ S
Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63
Query: 109 RGRLIVLRAP-RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDL 167
R + + P RFL + +TA + V L C +P + T + W N +D + +
Sbjct: 64 RTAKVAVAGPLRFLSQ-TESVTAFMGDTVLLKCEVIGEP-MPTIH-WQKNQ---QDLTPI 117
Query: 168 YVNKRIKI-DGGELTIYNVSLSDVGDYECVVKS-AIGRISSHVQLRIEGPPGPPGGVQIL 225
+ R+ + G L I + D+G Y C ++ A R + ++RI PG + L
Sbjct: 118 PGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFL 177
Query: 226 GIQRSSVTLEWTDSNSNGRPITGY 249
+ V +E D+ G ++GY
Sbjct: 178 QRPSNVVAIEGKDAVLEG-CVSGY 200
Score = 41.5 bits (93), Expect = 0.009
Identities = 46/207 (22%), Positives = 87/207 (42%), Gaps = 20/207 (9%)
Query: 430 VAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTR 489
V P LVS+R + ++W P +++ ++ + ++ +E E ++
Sbjct: 369 VVPVLVSSRF-----VRLSWRPPAEAKGNIQTFTV-----FFSREGDNRERALNTTQPGS 418
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWA--HDPTT 547
+ L+P+ Y +V+A+N G G ES + ++ + Q P N+ A PT+
Sbjct: 419 LQLTVGNLKPEAMYTFRVVAYNEWGPG-ESSQPIKVATQPELQVPGPVENLQAVSTSPTS 477
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNL 607
+ + W P P+ GY++ E+ N + + +KLE + Y+L
Sbjct: 478 ILITWE--PPAYANGPVQGYRLFCTEVSTGKEQ-NIEVDGLSYKLEG----LKKFTEYSL 530
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
R LAY+ G G + + D S
Sbjct: 531 RFLAYNRYGPGVSTDDITVVTLSDVPS 557
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 143 bits (346), Expect = 2e-33
Identities = 139/542 (25%), Positives = 222/542 (40%), Gaps = 51/542 (9%)
Query: 1 MYQCEAKNQLKA-SYSSAQLRVLSLKPSFKKHPLELETYGS----EGGNVTLKCKPEAAP 55
+Y+C A+N + + + A++R+LS P + L+ + EG + L+C P
Sbjct: 209 IYRCSARNPASSRTGNEAEVRILS-DPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYP 267
Query: 56 KPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P+FTW + VI K++ G NL+I ++ DD G+YTCV + + L V
Sbjct: 268 PPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV 327
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L P FL P + A + + C P+ W NG + S +
Sbjct: 328 LVPPWFLNH-PSNLYAYESMDIEFECTVSGKPV--PTVNWMKNGDVVIPSDYFQI----- 379
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP--------PGPPGGVQILG 226
+ G L I V SD G Y+CV ++ G + QL + P P P V +
Sbjct: 380 VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVL 439
Query: 227 IQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATV 285
+ V L W + + G T + R N E N + G + TV
Sbjct: 440 VSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNR------ERALNTTQP----GSLQLTV 489
Query: 286 STTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA-NVSGGGGKTGDLTIT 344
L P A+Y FR+ A N GPG+ S P + +T + P N+ + IT
Sbjct: 490 GN-LKPEAMYTFRVVAYNEWGPGESSQPI-KVATQPELQVPGPVENLQAVSTSPTSILIT 547
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P + NGP Y++F + E Q++ + + +T Y ++
Sbjct: 548 WEP--PAYANGPVQGYRLFCTEVSTGKE-QNI------EVDGLSYKLEGLKKFTEYSLRF 598
Query: 405 QAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLI 464
A+N GPG ++ +T+ + D+P PQ VS NS ++ V+W P + G +
Sbjct: 599 LAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQ--NGFIT 656
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
G+++++ K + E W L GL+ + Y +V A G GP S Y
Sbjct: 657 GYKIRHRKTTRRGE---METLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTA 713
Query: 525 RT 526
T
Sbjct: 714 ET 715
Score = 100 bits (239), Expect = 2e-20
Identities = 150/638 (23%), Positives = 258/638 (40%), Gaps = 58/638 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+YQCEA S S +V P E T G V LKC+ P PT
Sbjct: 114 LYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVT-AFMGDTVLLKCEVIGEPMPTIH 172
Query: 61 WKK---DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT---DESRGRLI- 113
W+K D I + + +G L I +L D G+Y C A+N + +E+ R++
Sbjct: 173 WQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILS 232
Query: 114 ---VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
+ R FL++ P + A L C P ++ W LR ++ L
Sbjct: 233 DPGLHRQLYFLQR-PSNVVAIEGKDAVLECCVSGYP--PPSFTW----LRGEEVIQLRSK 285
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
K + G L I NV+ D G Y CVV IS+ +L + PP L
Sbjct: 286 KYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSNL-YAYE 344
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
S+ +E+ + +G+P+ +W V+ IP+ G +
Sbjct: 345 SMDIEF-ECTVSGKPVP------TVNWMKNGDVV---IPSDY-FQIVGGSNLRILGVVKS 393
Query: 291 PWAIYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
Y+ A N G Q SA P P +S P AP +V + + ++W
Sbjct: 394 DEGFYQ--CVAENEAGNAQTSAQLIVPKPAIPSSSVLP-SAPRDVVPVLVSSRFVRLSWR 450
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P + G + +F+ R G E ++L + G++ V ++ YT +V A
Sbjct: 451 P-PAEAK-GNIQTFTVFFSREGDNRE-RALNTTQPGSLQLTVGNLKPEAMYT---FRVVA 504
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAP-QLVSARSFNSTALNVTWNPIDQSRERLRG-KLI 464
+N+ GPG S+ + + + ++ P + + A S + T++ +TW P + ++G +L
Sbjct: 505 YNEWGPGESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYANGPVQGYRLF 564
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
+ K++N E + + Y + GL+ T Y ++ +A+N G G ++
Sbjct: 565 CTEVSTGKEQNIEVDGLSYK---------LEGLKKFTEYSLRFLAYNRYGPGVSTDDITV 615
Query: 525 RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDT 584
T P PP +V++ + +++V W + + GYK+R +T
Sbjct: 616 VTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIR--HRKTTRRGEMET 673
Query: 585 IVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
+ P + L + + G Y+ +V A + G G S+
Sbjct: 674 LEP--NNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
Score = 64.5 bits (150), Expect = 1e-09
Identities = 59/210 (28%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 42 GGNVTLKCKPEA-APKPTFTWKKDNI--VIGAGGKRFITENGNLIIRQL-----SRDDEG 93
GGNV L C E+ P WKKD I +G ++ NG+L+I+ + + DEG
Sbjct: 54 GGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEG 113
Query: 94 VYTCVAK-NQYGTDESRGRLIVLRAP-RFLEKLPPRITAQVNSVVFLHCNADVDPILDTA 151
+Y C A G+ SR + + P RFL + +TA + V L C +P + T
Sbjct: 114 LYQCEASLGDSGSIISRTAKVAVAGPLRFLSQ-TESVTAFMGDTVLLKCEVIGEP-MPTI 171
Query: 152 YLWNHNGLRIKDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYECVVKS-AIGRISSHVQ 209
+ W N +D + + + R+ + G L I + D+G Y C ++ A R + +
Sbjct: 172 H-WQKNQ---QDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAE 227
Query: 210 LRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
+RI PG + L + V +E D+
Sbjct: 228 VRILSDPGLHRQLYFLQRPSNVVAIEGKDA 257
Score = 41.5 bits (93), Expect = 0.009
Identities = 46/207 (22%), Positives = 87/207 (42%), Gaps = 20/207 (9%)
Query: 430 VAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTR 489
V P LVS+R + ++W P +++ ++ + ++ +E E ++
Sbjct: 435 VVPVLVSSRF-----VRLSWRPPAEAKGNIQTFTV-----FFSREGDNRERALNTTQPGS 484
Query: 490 NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWA--HDPTT 547
+ L+P+ Y +V+A+N G G ES + ++ + Q P N+ A PT+
Sbjct: 485 LQLTVGNLKPEAMYTFRVVAYNEWGPG-ESSQPIKVATQPELQVPGPVENLQAVSTSPTS 543
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNL 607
+ + W P P+ GY++ E+ N + + +KLE + Y+L
Sbjct: 544 ILITWE--PPAYANGPVQGYRLFCTEVSTGKEQ-NIEVDGLSYKLEG----LKKFTEYSL 596
Query: 608 RVLAYSNGGDGRMSSPTIAFQIGDYHS 634
R LAY+ G G + + D S
Sbjct: 597 RFLAYNRYGPGVSTDDITVVTLSDVPS 623
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 135 bits (326), Expect = 5e-31
Identities = 164/652 (25%), Positives = 264/652 (40%), Gaps = 70/652 (10%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V L C AP P
Sbjct: 205 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVM--PGGSVNLTCVAVGAPMPY 262
Query: 59 FTW--------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W K+D + +G R + E N ++R + YTCVA + G E+
Sbjct: 263 VKWMMGAEELTKEDEMPVG----RNVLELSN-VVRSAN------YTCVAISSLGMIEATA 311
Query: 111 RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
++ V P+ ++ + TA SV + + +P+ T Y G++ + +
Sbjct: 312 QVTVKALPKPPIDLVVTETTA--TSVTLTWDSGNSEPV--TYY-----GIQYRAAGT--E 360
Query: 170 NKRIKIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGV 222
++DG T Y++ LS +Y + ++IGR S V+ R + P PP V
Sbjct: 361 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 420
Query: 223 QILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
Q + S++ ++W + GY R ++ S PN +
Sbjct: 421 QARMLSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLL 472
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
TV + LLP Y R+ A +G G PS P+ Q T P + PA+ +
Sbjct: 473 TTVGS-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQ 529
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
++W P Q ++ ++W + + + + +Y + T Y
Sbjct: 530 LSWLLPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRF 580
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGK 462
++ A +D+G G + + +A+ P PQ V S ST + V+W P + G
Sbjct: 581 QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPADSRNGV 638
Query: 463 LIGHRLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+ + + Y E++ + +SR +W L VGL+ T Y V V A G GPES
Sbjct: 639 ITQYSVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESS 697
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMST 580
L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 698 PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPR 757
Query: 581 ANDTI--VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
I V + E IS + P +Y++ V AY+ GDG S P I G
Sbjct: 758 GLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTG 809
Score = 130 bits (314), Expect = 2e-29
Identities = 155/640 (24%), Positives = 259/640 (40%), Gaps = 58/640 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 114 VLR----APRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
+R APRF +PP + V L C A P+ ++ L +D ++
Sbjct: 224 YVRVRRVAPRF--SIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED--EMP 279
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
V + + L + NV S +Y CV S++G I + Q+ ++ P PP + +
Sbjct: 280 VGRNV------LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETT 331
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+SVTL W NS P+T Y + R + EVD R ++
Sbjct: 332 ATSVTLTWDSGNSE--PVTYYGIQYRAAGTEGPF---------QEVDGV-ATTRYSIGG- 378
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP- 347
L P++ Y FR+ A+N +G G PS + + T P P V + + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPS-EAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Query: 348 -LPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P L G ++Y RR + K+ + + S Y ++V A
Sbjct: 438 EEPNGLVRGYRVYYTPDSRRPPN-------AWHKHNTDAGLLTTVGSLLPGITYSLRVLA 490
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S + + + + +P P A + T + ++W Q R +I +
Sbjct: 491 FTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMY 543
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L YW E+++++ + ++ + + L+PDT Y ++ A + G G + RT
Sbjct: 544 ELVYWAAEDEDQQ--HKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 601
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + TT+RV W + + Y V +D + +
Sbjct: 602 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE-DRGRHVVD 660
Query: 587 PIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I + ++ + + Y + V A+++ G G SSP +
Sbjct: 661 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 700
Score = 98.3 bits (234), Expect = 8e-20
Identities = 83/333 (24%), Positives = 144/333 (43%), Gaps = 15/333 (4%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P +Y F++ A + +G G P+ + T+ P P V + + ++W P
Sbjct: 572 LKPDTLYRFQLAARSDMGVGV-FTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP 630
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P +NG Y + + E + ++ ++ + +T Y V V+A
Sbjct: 631 PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSW--DLVGLEKWTEYRVWVRAHT 688
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
D+GPGPES V + + ED+P P+ V NSTA++V W S++ G++ G+++
Sbjct: 689 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ--HGQIRGYQV 746
Query: 469 KYWKQENKEEE---CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
Y + EN E I + I GL P+T Y V V A+ + G+G S+ +
Sbjct: 747 TYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT 806
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P +P ++ A + L+ W P LLGY+++ D+ D
Sbjct: 807 TTGAVPGRPTMMISTTAMNTALLQ--WH--PPKELPGELLGYRLQYCRADEARPNTIDFG 862
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+H ++ + G +Y R+ A + G G
Sbjct: 863 KDDQH---FTVTGLHKGTTYIFRLAAKNRAGLG 892
Score = 63.7 bits (148), Expect = 2e-09
Identities = 86/331 (25%), Positives = 141/331 (42%), Gaps = 31/331 (9%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 693 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 751
Query: 257 WNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQ 316
N +P + +V ++ T + L P Y + A G G S P
Sbjct: 752 ENGE----PRGLPIIQDVMLAEAQE--TTISGLTPETTYSVTVAAYTTKGDGARSKPKI- 804
Query: 317 FSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSL 376
+T+G P +S T + W P P L G + Y++ + R E ++
Sbjct: 805 VTTTGAVPGRPTMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEARPNTI 859
Query: 377 LLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLV 435
K T +H +TY + ++ A N G G E E I + ED+P PQ +
Sbjct: 860 DFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFEK-EIRTPEDLPSGFPQNL 913
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
++ + W+P ER G++I + + + + N ++E + ++ TR +
Sbjct: 914 HVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR--FTLT 967
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
GL+PDT Y +KV A+ S G GP S RT
Sbjct: 968 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 998
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 22/202 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENGN-- 81
KP F K P E +T G GG + C+ PKP TW K + + I ++G
Sbjct: 32 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 -LIIRQLS-RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
L I+ L + DE +Y C A N G + +L VL + P ++ +
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 150 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R S+ L +
Sbjct: 204 KYECVATNSAGTRYSAPANLYV 225
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 135 bits (326), Expect = 5e-31
Identities = 164/652 (25%), Positives = 264/652 (40%), Gaps = 70/652 (10%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V L C AP P
Sbjct: 205 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVM--PGGSVNLTCVAVGAPMPY 262
Query: 59 FTW--------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W K+D + +G R + E N ++R + YTCVA + G E+
Sbjct: 263 VKWMMGAEELTKEDEMPVG----RNVLELSN-VVRSAN------YTCVAISSLGMIEATA 311
Query: 111 RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
++ V P+ ++ + TA SV + + +P+ T Y G++ + +
Sbjct: 312 QVTVKALPKPPIDLVVTETTA--TSVTLTWDSGNSEPV--TYY-----GIQYRAAGT--E 360
Query: 170 NKRIKIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGV 222
++DG T Y++ LS +Y + ++IGR S V+ R + P PP V
Sbjct: 361 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 420
Query: 223 QILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
Q + S++ ++W + GY R ++ S PN +
Sbjct: 421 QARMLSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLL 472
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
TV + LLP Y R+ A +G G PS P+ Q T P + PA+ +
Sbjct: 473 TTVGS-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQ 529
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
++W P Q ++ ++W + + + + +Y + T Y
Sbjct: 530 LSWLLPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRF 580
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGK 462
++ A +D+G G + + +A+ P PQ V S ST + V+W P + G
Sbjct: 581 QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPADSRNGV 638
Query: 463 LIGHRLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+ + + Y E++ + +SR +W L VGL+ T Y V V A G GPES
Sbjct: 639 ITQYSVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESS 697
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMST 580
L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 698 PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPR 757
Query: 581 ANDTI--VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
I V + E IS + P +Y++ V AY+ GDG S P I G
Sbjct: 758 GLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTG 809
Score = 130 bits (314), Expect = 2e-29
Identities = 155/640 (24%), Positives = 259/640 (40%), Gaps = 58/640 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 114 VLR----APRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
+R APRF +PP + V L C A P+ ++ L +D ++
Sbjct: 224 YVRVRRVAPRF--SIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED--EMP 279
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
V + + L + NV S +Y CV S++G I + Q+ ++ P PP + +
Sbjct: 280 VGRNV------LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETT 331
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+SVTL W NS P+T Y + R + EVD R ++
Sbjct: 332 ATSVTLTWDSGNSE--PVTYYGIQYRAAGTEGPF---------QEVDGV-ATTRYSIGG- 378
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP- 347
L P++ Y FR+ A+N +G G PS + + T P P V + + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPS-EAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Query: 348 -LPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P L G ++Y RR + K+ + + S Y ++V A
Sbjct: 438 EEPNGLVRGYRVYYTPDSRRPPN-------AWHKHNTDAGLLTTVGSLLPGITYSLRVLA 490
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S + + + + +P P A + T + ++W Q R +I +
Sbjct: 491 FTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMY 543
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L YW E+++++ + ++ + + L+PDT Y ++ A + G G + RT
Sbjct: 544 ELVYWAAEDEDQQ--HKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 601
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + TT+RV W + + Y V +D + +
Sbjct: 602 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE-DRGRHVVD 660
Query: 587 PIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I + ++ + + Y + V A+++ G G SSP +
Sbjct: 661 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 700
Score = 98.3 bits (234), Expect = 8e-20
Identities = 83/333 (24%), Positives = 144/333 (43%), Gaps = 15/333 (4%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P +Y F++ A + +G G P+ + T+ P P V + + ++W P
Sbjct: 572 LKPDTLYRFQLAARSDMGVGV-FTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP 630
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P +NG Y + + E + ++ ++ + +T Y V V+A
Sbjct: 631 PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSW--DLVGLEKWTEYRVWVRAHT 688
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
D+GPGPES V + + ED+P P+ V NSTA++V W S++ G++ G+++
Sbjct: 689 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ--HGQIRGYQV 746
Query: 469 KYWKQENKEEE---CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
Y + EN E I + I GL P+T Y V V A+ + G+G S+ +
Sbjct: 747 TYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT 806
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P +P ++ A + L+ W P LLGY+++ D+ D
Sbjct: 807 TTGAVPGRPTMMISTTAMNTALLQ--WH--PPKELPGELLGYRLQYCRADEARPNTIDFG 862
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+H ++ + G +Y R+ A + G G
Sbjct: 863 KDDQH---FTVTGLHKGTTYIFRLAAKNRAGLG 892
Score = 63.7 bits (148), Expect = 2e-09
Identities = 86/331 (25%), Positives = 141/331 (42%), Gaps = 31/331 (9%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 693 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 751
Query: 257 WNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQ 316
N +P + +V ++ T + L P Y + A G G S P
Sbjct: 752 ENGE----PRGLPIIQDVMLAEAQE--TTISGLTPETTYSVTVAAYTTKGDGARSKPKI- 804
Query: 317 FSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSL 376
+T+G P +S T + W P P L G + Y++ + R E ++
Sbjct: 805 VTTTGAVPGRPTMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEARPNTI 859
Query: 377 LLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLV 435
K T +H +TY + ++ A N G G E E I + ED+P PQ +
Sbjct: 860 DFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFEK-EIRTPEDLPSGFPQNL 913
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
++ + W+P ER G++I + + + + N ++E + ++ TR +
Sbjct: 914 HVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR--FTLT 967
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
GL+PDT Y +KV A+ S G GP S RT
Sbjct: 968 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 998
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 22/202 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENGN-- 81
KP F K P E +T G GG + C+ PKP TW K + + I ++G
Sbjct: 32 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 -LIIRQLS-RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
L I+ L + DE +Y C A N G + +L VL + P ++ +
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 150 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R S+ L +
Sbjct: 204 KYECVATNSAGTRYSAPANLYV 225
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 135 bits (326), Expect = 5e-31
Identities = 164/652 (25%), Positives = 264/652 (40%), Gaps = 70/652 (10%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V L C AP P
Sbjct: 225 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVM--PGGSVNLTCVAVGAPMPY 282
Query: 59 FTW--------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W K+D + +G R + E N ++R + YTCVA + G E+
Sbjct: 283 VKWMMGAEELTKEDEMPVG----RNVLELSN-VVRSAN------YTCVAISSLGMIEATA 331
Query: 111 RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
++ V P+ ++ + TA SV + + +P+ T Y G++ + +
Sbjct: 332 QVTVKALPKPPIDLVVTETTA--TSVTLTWDSGNSEPV--TYY-----GIQYRAAGT--E 380
Query: 170 NKRIKIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGV 222
++DG T Y++ LS +Y + ++IGR S V+ R + P PP V
Sbjct: 381 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 440
Query: 223 QILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
Q + S++ ++W + GY R ++ S PN +
Sbjct: 441 QARMLSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLL 492
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
TV + LLP Y R+ A +G G PS P+ Q T P + PA+ +
Sbjct: 493 TTVGS-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQ 549
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
++W P Q ++ ++W + + + + +Y + T Y
Sbjct: 550 LSWLLPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRF 600
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGK 462
++ A +D+G G + + +A+ P PQ V S ST + V+W P + G
Sbjct: 601 QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPADSRNGV 658
Query: 463 LIGHRLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+ + + Y E++ + +SR +W L VGL+ T Y V V A G GPES
Sbjct: 659 ITQYSVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESS 717
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMST 580
L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 718 PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPR 777
Query: 581 ANDTI--VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
I V + E IS + P +Y++ V AY+ GDG S P I G
Sbjct: 778 GLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTG 829
Score = 130 bits (314), Expect = 2e-29
Identities = 155/640 (24%), Positives = 259/640 (40%), Gaps = 58/640 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 124 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 183
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 184 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 243
Query: 114 VLR----APRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
+R APRF +PP + V L C A P+ ++ L +D ++
Sbjct: 244 YVRVRRVAPRF--SIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED--EMP 299
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
V + + L + NV S +Y CV S++G I + Q+ ++ P PP + +
Sbjct: 300 VGRNV------LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETT 351
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+SVTL W NS P+T Y + R + EVD R ++
Sbjct: 352 ATSVTLTWDSGNSE--PVTYYGIQYRAAGTEGPF---------QEVDGV-ATTRYSIGG- 398
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP- 347
L P++ Y FR+ A+N +G G PS + + T P P V + + W P
Sbjct: 399 LSPFSEYAFRVLAVNSIGRGPPS-EAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 457
Query: 348 -LPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P L G ++Y RR + K+ + + S Y ++V A
Sbjct: 458 EEPNGLVRGYRVYYTPDSRRPPN-------AWHKHNTDAGLLTTVGSLLPGITYSLRVLA 510
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S + + + + +P P A + T + ++W Q R +I +
Sbjct: 511 FTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMY 563
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L YW E+++++ + ++ + + L+PDT Y ++ A + G G + RT
Sbjct: 564 ELVYWAAEDEDQQ--HKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 621
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + TT+RV W + + Y V +D + +
Sbjct: 622 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE-DRGRHVVD 680
Query: 587 PIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I + ++ + + Y + V A+++ G G SSP +
Sbjct: 681 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 720
Score = 98.3 bits (234), Expect = 8e-20
Identities = 83/333 (24%), Positives = 144/333 (43%), Gaps = 15/333 (4%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P +Y F++ A + +G G P+ + T+ P P V + + ++W P
Sbjct: 592 LKPDTLYRFQLAARSDMGVGV-FTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP 650
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P +NG Y + + E + ++ ++ + +T Y V V+A
Sbjct: 651 PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSW--DLVGLEKWTEYRVWVRAHT 708
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
D+GPGPES V + + ED+P P+ V NSTA++V W S++ G++ G+++
Sbjct: 709 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ--HGQIRGYQV 766
Query: 469 KYWKQENKEEE---CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
Y + EN E I + I GL P+T Y V V A+ + G+G S+ +
Sbjct: 767 TYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT 826
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P +P ++ A + L+ W P LLGY+++ D+ D
Sbjct: 827 TTGAVPGRPTMMISTTAMNTALLQ--WH--PPKELPGELLGYRLQYCRADEARPNTIDFG 882
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+H ++ + G +Y R+ A + G G
Sbjct: 883 KDDQH---FTVTGLHKGTTYIFRLAAKNRAGLG 912
Score = 63.7 bits (148), Expect = 2e-09
Identities = 86/331 (25%), Positives = 141/331 (42%), Gaps = 31/331 (9%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 713 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 771
Query: 257 WNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQ 316
N +P + +V ++ T + L P Y + A G G S P
Sbjct: 772 ENGE----PRGLPIIQDVMLAEAQE--TTISGLTPETTYSVTVAAYTTKGDGARSKPKI- 824
Query: 317 FSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSL 376
+T+G P +S T + W P P L G + Y++ + R E ++
Sbjct: 825 VTTTGAVPGRPTMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEARPNTI 879
Query: 377 LLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLV 435
K T +H +TY + ++ A N G G E E I + ED+P PQ +
Sbjct: 880 DFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFEK-EIRTPEDLPSGFPQNL 933
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
++ + W+P ER G++I + + + + N ++E + ++ TR +
Sbjct: 934 HVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR--FTLT 987
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
GL+PDT Y +KV A+ S G GP S RT
Sbjct: 988 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 1018
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 22/202 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENGN-- 81
KP F K P E +T G GG + C+ PKP TW K + + I ++G
Sbjct: 52 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 109
Query: 82 -LIIRQLS-RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
L I+ L + DE +Y C A N G + +L VL + P ++ +
Sbjct: 110 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 169
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 170 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 223
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R S+ L +
Sbjct: 224 KYECVATNSAGTRYSAPANLYV 245
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 132 bits (318), Expect = 5e-30
Identities = 167/661 (25%), Positives = 268/661 (40%), Gaps = 79/661 (11%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V L C AP P
Sbjct: 205 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVM--PGGSVNLTCVAVGAPMPY 262
Query: 59 FTW--------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W K+D + +G R + E N ++R + YTCVA + G E+
Sbjct: 263 VKWMMGAEELTKEDEMPVG----RNVLELSN-VVRSAN------YTCVAISSLGMIEATA 311
Query: 111 RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
++ V P+ ++ + TA SV + + +P+ T Y G++ + +
Sbjct: 312 QVTVKALPKPPIDLVVTETTA--TSVTLTWDSGNSEPV--TYY-----GIQYRAAGT--E 360
Query: 170 NKRIKIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGV 222
++DG T Y++ LS +Y + ++IGR S V+ R + P PP V
Sbjct: 361 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 420
Query: 223 QILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
Q + S++ ++W + GY R ++ S PN +
Sbjct: 421 QARMLSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLL 472
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
TV + LLP Y R+ A +G G PS P+ Q T P + PA+ +
Sbjct: 473 TTVGS-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQ 529
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
++W P Q ++ ++W + + + + +Y + T Y
Sbjct: 530 LSWLLPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRF 580
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGK 462
++ A +D+G G + + +A+ P PQ V S ST + V+W P + G
Sbjct: 581 QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPADSRNGV 638
Query: 463 LIGHRLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+ + + Y E++ + +SR +W L VGL+ T Y V V A G GPES
Sbjct: 639 ITQYSVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESS 697
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD----- 575
L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 698 PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPR 757
Query: 576 -----QDMSTANDTIVPIEHK-LEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQI 629
QD+ A P E + E IS + P +Y++ V AY+ GDG S P I
Sbjct: 758 GLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT 817
Query: 630 G 630
G
Sbjct: 818 G 818
Score = 130 bits (314), Expect = 2e-29
Identities = 156/640 (24%), Positives = 259/640 (40%), Gaps = 58/640 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 104 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 163
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 164 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 223
Query: 114 VLR----APRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
+R APRF +PP + V L C A P+ ++ L +D ++
Sbjct: 224 YVRVRRVAPRF--SIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED--EMP 279
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
V + + L + NV S +Y CV S++G I + Q+ ++ P PP + +
Sbjct: 280 VGRNV------LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETT 331
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+SVTL W NS P+T Y + R + EVD R ++
Sbjct: 332 ATSVTLTWDSGNSE--PVTYYGIQYRAAGTEGPF---------QEVDGV-ATTRYSIGG- 378
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P++ Y FR+ A+N +G G PS + + T P P V + + W P
Sbjct: 379 LSPFSEYAFRVLAVNSIGRGPPSE-AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Query: 349 --PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P L G ++Y RR + + +G+ + I+ Y ++V A
Sbjct: 438 EEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGIT-------YSLRVLA 490
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S + + + + +P P A + T + ++W Q R +I +
Sbjct: 491 FTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMY 543
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L YW E+++++ T+ + L+PDT Y ++ A + G G + RT
Sbjct: 544 ELVYWAAEDEDQQHKVTFDPTSSY--TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 601
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + TT+RV W + + Y V +D + +
Sbjct: 602 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE-DRGRHVVD 660
Query: 587 PIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I + ++ + + Y + V A+++ G G SSP +
Sbjct: 661 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 700
Score = 72.1 bits (169), Expect = 6e-12
Identities = 95/421 (22%), Positives = 173/421 (41%), Gaps = 33/421 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP V + + ++V + W ++ R G + T ++ + + V
Sbjct: 606 PSAPPQKVMCVSMGSTTVRVSWVPPPADSR--NGVI----TQYSVAYEAVDGEDRGRHVV 659
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
D + + L W Y ++A +GPG S+P T D P P V
Sbjct: 660 DGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPV-LVRTDEDVPSGPPRKVEVE 718
Query: 335 GGKTGDLTITWT-PLPTSLQNGPGIHYKIFWRR--NGSEVEF---QSLLLKKYG----NI 384
+ + + W P+P S Q+G Y++ + R NG Q ++L +
Sbjct: 719 PLNSTAVHVYWKLPVP-SKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEES 777
Query: 385 GTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTA 444
Y IS T Y V V A+ G G S+ + + +P ++S + N TA
Sbjct: 778 EDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMN-TA 836
Query: 445 LNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYY 504
L + W+P + L G+L+G+RL+Y + + I + + +++ + GL T Y
Sbjct: 837 L-LQWHP----PKELPGELLGYRLQYCRADEARPNTIDF-GKDDQHFT-VTGLHKGTTYI 889
Query: 505 VKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPL 564
++ A N AG G E E+ + RT P P +++V +T + W +
Sbjct: 890 FRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRI 948
Query: 565 LGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
+ Y V +++ N I ++ + P +Y+++V A+++ G G + SP+
Sbjct: 949 ISYTVVFRDINSQQELQN-----ITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPL-SPS 1002
Query: 625 I 625
I
Sbjct: 1003 I 1003
Score = 60.1 bits (139), Expect = 3e-08
Identities = 88/335 (26%), Positives = 143/335 (42%), Gaps = 30/335 (8%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 693 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 751
Query: 257 WNSTWYVISENIPNVMEVD-RYNGRKRATVSTT---LLPWAIYEFRIQAINILGPGQPSA 312
N + I +VM + ++ + TT L P Y + A G G S
Sbjct: 752 ENGEPRGLPI-IQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSK 810
Query: 313 PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVE 372
P +T+G P +S T + W P P L G + Y++ + R E
Sbjct: 811 PKI-VTTTGAVPGRPTMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEAR 864
Query: 373 FQSLLLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVA 431
++ K T +H +TY + ++ A N G G E E I + ED+P
Sbjct: 865 PNTIDFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFEK-EIRTPEDLPSGF 918
Query: 432 PQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNW 491
PQ + ++ + W+P ER G++I + + + + N ++E + ++ TR
Sbjct: 919 PQNLHVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR-- 972
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
+ GL+PDT Y +KV A+ S G GP S RT
Sbjct: 973 FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 1007
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 22/202 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENGN-- 81
KP F K P E +T G GG + C+ PKP TW K + + I ++G
Sbjct: 32 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 89
Query: 82 -LIIRQLS-RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
L I+ L + DE +Y C A N G + +L VL + P ++ +
Sbjct: 90 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 150 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R S+ L +
Sbjct: 204 KYECVATNSAGTRYSAPANLYV 225
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 131 bits (317), Expect = 7e-30
Identities = 167/661 (25%), Positives = 266/661 (40%), Gaps = 79/661 (11%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V L C AP P
Sbjct: 195 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVM--PGGSVNLTCVAVGAPMPY 252
Query: 59 FTW--------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W K+D + +G R + E N ++R + YTCVA + G E+
Sbjct: 253 VKWMMGAEELTKEDEMPVG----RNVLELSN-VVRSAN------YTCVAISSLGMIEATA 301
Query: 111 RLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
++ V P+ ++ + TA SV + + +P+ T Y G++ + +
Sbjct: 302 QVTVKALPKPPIDLVVTETTA--TSVTLTWDSGNSEPV--TYY-----GIQYRAAGT--E 350
Query: 170 NKRIKIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGV 222
++DG T Y++ LS +Y + ++IGR S V+ R + P PP V
Sbjct: 351 GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV 410
Query: 223 QILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
Q + S++ ++W + GY R ++ S PN +
Sbjct: 411 QARMLSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLL 462
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
TV + LLP Y R+ A +G G PS P+ Q T P + PA+ +
Sbjct: 463 TTVGS-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQ 519
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDV 402
++W P Q ++ ++W + + + + +Y + T Y
Sbjct: 520 LSWLLPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRF 570
Query: 403 KVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW--NPIDQSRERLR 460
++ A +D+G G + + +A+ P PQ V S ST + V+W P D +
Sbjct: 571 QLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVIT 630
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+ H E++ + +SR +W L VGL+ T Y V V A G GPES
Sbjct: 631 QYSVAHEAV--DGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESS 687
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD----- 575
L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 688 PVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPR 747
Query: 576 -----QDMSTANDTIVPIEHK-LEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQI 629
QD+ A P E + E IS + P +Y++ V AY+ GDG S P I
Sbjct: 748 GLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTT 807
Query: 630 G 630
G
Sbjct: 808 G 808
Score = 129 bits (312), Expect = 3e-29
Identities = 156/640 (24%), Positives = 259/640 (40%), Gaps = 58/640 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 94 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 153
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 154 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 213
Query: 114 VLR----APRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
+R APRF +PP + V L C A P+ ++ L +D ++
Sbjct: 214 YVRVRRVAPRF--SIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED--EMP 269
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
V + + L + NV S +Y CV S++G I + Q+ ++ P PP + +
Sbjct: 270 VGRNV------LELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETT 321
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+SVTL W NS P+T Y + R + EVD R ++
Sbjct: 322 ATSVTLTWDSGNSE--PVTYYGIQYRAAGTEGPF---------QEVDGV-ATTRYSIGG- 368
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P++ Y FR+ A+N +G G PS + + T P P V + + W P
Sbjct: 369 LSPFSEYAFRVLAVNSIGRGPPSE-AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 427
Query: 349 --PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P L G ++Y RR + + +G+ + I+ Y ++V A
Sbjct: 428 EEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGIT-------YSLRVLA 480
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S + + + + +P P A + T + ++W Q R +I +
Sbjct: 481 FTAVGDGPPSPTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMY 533
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L YW E+++++ T+ + L+PDT Y ++ A + G G + RT
Sbjct: 534 ELVYWAAEDEDQQHKVTFDPTSSY--TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART 591
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + TT+RV W + + Y V +D + +
Sbjct: 592 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAHEAVDGE-DRGRHVVD 650
Query: 587 PIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I + ++ + + Y + V A+++ G G SSP +
Sbjct: 651 GISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 690
Score = 70.5 bits (165), Expect = 2e-11
Identities = 95/421 (22%), Positives = 172/421 (40%), Gaps = 33/421 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP V + + ++V + W ++ R G + T ++ + V
Sbjct: 596 PSAPPQKVMCVSMGSTTVRVSWVPPPADSR--NGVI----TQYSVAHEAVDGEDRGRHVV 649
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
D + + L W Y ++A +GPG S+P T D P P V
Sbjct: 650 DGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPV-LVRTDEDVPSGPPRKVEVE 708
Query: 335 GGKTGDLTITWT-PLPTSLQNGPGIHYKIFWRR--NGSEVEF---QSLLLKKYG----NI 384
+ + + W P+P S Q+G Y++ + R NG Q ++L +
Sbjct: 709 PLNSTAVHVYWKLPVP-SKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEES 767
Query: 385 GTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTA 444
Y IS T Y V V A+ G G S+ + + +P ++S + N TA
Sbjct: 768 EDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMN-TA 826
Query: 445 LNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYY 504
L + W+P + L G+L+G+RL+Y + + I + + +++ + GL T Y
Sbjct: 827 L-LQWHP----PKELPGELLGYRLQYCRADEARPNTIDF-GKDDQHFT-VTGLHKGTTYI 879
Query: 505 VKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPL 564
++ A N AG G E E+ + RT P P +++V +T + W +
Sbjct: 880 FRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRI 938
Query: 565 LGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
+ Y V +++ N I ++ + P +Y+++V A+++ G G + SP+
Sbjct: 939 ISYTVVFRDINSQQELQN-----ITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPL-SPS 992
Query: 625 I 625
I
Sbjct: 993 I 993
Score = 60.1 bits (139), Expect = 3e-08
Identities = 88/335 (26%), Positives = 143/335 (42%), Gaps = 30/335 (8%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 683 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 741
Query: 257 WNSTWYVISENIPNVMEVD-RYNGRKRATVSTT---LLPWAIYEFRIQAINILGPGQPSA 312
N + I +VM + ++ + TT L P Y + A G G S
Sbjct: 742 ENGEPRGLPI-IQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSK 800
Query: 313 PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVE 372
P +T+G P +S T + W P P L G + Y++ + R E
Sbjct: 801 PKI-VTTTGAVPGRPTMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEAR 854
Query: 373 FQSLLLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVA 431
++ K T +H +TY + ++ A N G G E E I + ED+P
Sbjct: 855 PNTIDFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFEK-EIRTPEDLPSGF 908
Query: 432 PQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNW 491
PQ + ++ + W+P ER G++I + + + + N ++E + ++ TR
Sbjct: 909 PQNLHVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR-- 962
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
+ GL+PDT Y +KV A+ S G GP S RT
Sbjct: 963 FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 997
Score = 51.2 bits (117), Expect = 1e-05
Identities = 58/202 (28%), Positives = 86/202 (42%), Gaps = 22/202 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENGN-- 81
KP F K P E +T G GG + C+ PKP TW K + + I ++G
Sbjct: 22 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 79
Query: 82 -LIIRQLS-RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
L I+ L + DE +Y C A N G + +L VL + P ++ +
Sbjct: 80 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 140 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 193
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R S+ L +
Sbjct: 194 KYECVATNSAGTRYSAPANLYV 215
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 130 bits (314), Expect = 2e-29
Identities = 164/647 (25%), Positives = 267/647 (41%), Gaps = 60/647 (9%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YSS +RV + P F P+ E GGNV + C +P P
Sbjct: 205 YECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM--PGGNVNITCVAVGSPMPY 262
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W + + + N L + + +D + CVA + G E+ ++ V P
Sbjct: 263 VKWMQGAEDLTPEDDMPVGRNV-LELTDV-KDSANYHPCVAMSSLGVIEAVAQITVKSLP 320
Query: 119 RFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+ P +T S+ + + DP+ + Y+ + K Y +IK D
Sbjct: 321 K--APGTPMVTENTATSITITWDSGNPDPV--SYYVIEYKS---KSQDGPY---QIKEDI 370
Query: 178 GELTIYNVS-LSDVGDYECVVKS--AIGR--ISSHVQLRI--EGPPGPPGGVQILGIQRS 230
T Y++ LS +YE V + +IG+ S V R + P PP VQ + +
Sbjct: 371 -TTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSAT 429
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVSTTL 289
++ ++W + I GY + +Y + P V ++N T +L
Sbjct: 430 TMIVQWEEPVEPNGLIRGYRV---------YYTMEPEHP-VGNWQKHNVDDSLLTTVGSL 479
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
L Y R+ A +G G S P Q T P + P N+ +T++W+P P
Sbjct: 480 LEDETYTVRVLAFTSVGDGPLSDPI-QVKTQQGVPGQ-PMNLRAEARSETSITLSWSP-P 536
Query: 350 TSLQNGPGIHYKIFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
+ I Y++ +R +G EV + + +YVV T Y ++ A
Sbjct: 537 ---RQESIIKYELLFREGDHGREVG------RTFDPTTSYVVEDLKPN--TEYAFRLAAR 585
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
+ G G + VV + + P PQ V S STA+ V+W P E G L+G+
Sbjct: 586 SPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRP--PPPETHNGALVGYS 643
Query: 468 LKYWK--QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
++Y E+ E + + + TT L+ L+ T Y + +A G GPES + R
Sbjct: 644 VRYRPLGSEDPEPKEVNGIPPTTTQ-ILLEALEKWTQYRITTVAHTEVGPGPESSPVVVR 702
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P PP V A + T +RV+WR P + + GY+V +++ + +I
Sbjct: 703 TDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMERREARGRRSI 762
Query: 586 --VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
V + E I+N+ P +Y++ V AY+ GDG S P + G
Sbjct: 763 KDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKG 809
Score = 126 bits (303), Expect = 3e-28
Identities = 150/639 (23%), Positives = 257/639 (40%), Gaps = 56/639 (8%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL---SLKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A+N + A+L VL L F + + E T+ C P
Sbjct: 104 VYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPD 163
Query: 57 PTFTWKKDNIVI---GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P TW KD + + + G+ +G L I D+G Y CVA N G S +
Sbjct: 164 PEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANL 223
Query: 114 VLR----APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
+R APRF LP V + C A P+ ++ L +D D+ V
Sbjct: 224 YVRVRRVAPRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED--DMPV 280
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYE-CVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ + ELT + D +Y CV S++G I + Q+ ++ P PG +
Sbjct: 281 GRNVL----ELT----DVKDSANYHPCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 332
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+S+T+ W N + P++ Y++ ++ Y I E+I RY+
Sbjct: 333 ATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS-------IGG 379
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW-TP 347
L P + YE + A+N +G G PS S T P P NV + + W P
Sbjct: 380 LSPNSEYEIWVSAVNSIGQGPPS-ESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEP 438
Query: 348 L-PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
+ P L G ++Y + E E +K+ + + + S Y V+V A
Sbjct: 439 VEPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLA 491
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S+ + + + + +P P + A + + T++ ++W+P Q +I +
Sbjct: 492 FTSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE------SIIKY 544
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L + + ++ E + T+ ++ L+P+T Y ++ A + G G + +RT
Sbjct: 545 ELLFREGDHGREVGRTFDPTTS---YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 601
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ P PP V + T + V WR P L+GY VR L + +
Sbjct: 602 LQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNG 661
Query: 587 PIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
+ + + Y + +A++ G G SSP +
Sbjct: 662 IPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVV 700
Score = 109 bits (263), Expect = 2e-23
Identities = 108/429 (25%), Positives = 181/429 (42%), Gaps = 29/429 (6%)
Query: 202 GRISSHVQLRIE-GPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNST 260
G +S +Q++ + G PG P ++ +S+TL W+ I Y L R +
Sbjct: 498 GPLSDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQES--IIKYELLFREGDHGR 555
Query: 261 WYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTS 320
EV R + V L P Y FR+ A + G G P + T
Sbjct: 556 ------------EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGA-FTPVVRQRTL 602
Query: 321 GDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKK 380
KP P +V ++ + ++W P P NG + Y + +R GSE + + +
Sbjct: 603 QSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSE-DPEPKEVNG 661
Query: 381 YGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSF 440
T ++ + + +T Y + A ++GPGPES V + + ED+P P+ V A +
Sbjct: 662 IPPTTTQIL-LEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEAL 720
Query: 441 NSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE---EECIYYLSRTTRNWALIVGL 497
N+TA+ V W R+ G++ G+++ Y + E +E I + +I L
Sbjct: 721 NATAIRVLWRSPAPGRQH--GQIRGYQVHYVRMERREARGRRSIKDVMLADAQEMVITNL 778
Query: 498 QPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQP 557
QP+T Y + V A+ G+G S+ + T +P SV R W
Sbjct: 779 QPETAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLAR--WEPPAG 836
Query: 558 TNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGD 617
T E++ +LGY+++ D A P E + A S + G +Y R+ A S GG
Sbjct: 837 TAEDQ-VLGYRLQFGRED-STPLATLEFPPSEDRYTA--SGVHKGATYVFRLAARSPGGL 892
Query: 618 GRMSSPTIA 626
G ++ ++
Sbjct: 893 GEEAAEVLS 901
Score = 56.0 bits (129), Expect = 4e-07
Identities = 60/202 (29%), Positives = 86/202 (42%), Gaps = 24/202 (11%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT----ENGN 81
P F K P + G G + C+ PKP TW K + + +RF T E+
Sbjct: 33 PRFIKEPKD--QIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNS--QRFETIEFDESAG 88
Query: 82 LIIR-QLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
++R Q R DE VY CVA+N G +L VLR + P P++ +
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ C A +P D W + L + S+ N RIK + G L I + +D G
Sbjct: 149 TRTATMLCAASGNP--DPEITWFKDFLPVDPSAS---NGRIKQLRSGALQIESSEETDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R SS L +
Sbjct: 204 KYECVATNSAGVRYSSPANLYV 225
Score = 52.8 bits (121), Expect = 4e-06
Identities = 83/418 (19%), Positives = 154/418 (36%), Gaps = 29/418 (6%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P PP V+ + ++ +++ + W ++ + GY + R + P
Sbjct: 606 PSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRP--------LGSEDPEPK 657
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
EV+ + L W Y A +GPG S+P T D P P V
Sbjct: 658 EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVV-VRTDEDVPSAPPRKVE 716
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS 392
+ + W Q+G Y++ + R +K + I+
Sbjct: 717 AEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMERREARGRRSIKDVMLADAQEMVIT 776
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPI 452
+ T Y + V A+ G G S+ + + + + +S + +L W P
Sbjct: 777 NLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAV--LGRPTLSVQQTPEGSLLARWEPP 834
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
+ E +++G+RL++ ++++ + + R A G+ Y ++ A +
Sbjct: 835 AGTAE---DQVLGYRLQFGREDSTPLATLEFPPSEDRYTAS--GVHKGATYVFRLAARSP 889
Query: 513 AGEGPESERYL---ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
G G E+ L E T R PQ A+ N A T+ + W P ++ Y V
Sbjct: 890 GGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAG---TVLLRWLPPVPAERNGAIVKYTV 946
Query: 570 RLWELDQDMSTANDTIVPIEHKLEAY----ISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+ E + A +T +P A + + P +Y+L+V A++ G G S P
Sbjct: 947 AVREAGA-LGPARETELPAGRLSRARRTLTLQGLKPDTAYDLQVRAHTRRGPGPFSPP 1003
Score = 42.3 bits (95), Expect = 0.005
Identities = 75/300 (25%), Positives = 114/300 (38%), Gaps = 23/300 (7%)
Query: 285 VSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTIT 344
V T L P Y + A + G G S P T G +V G L
Sbjct: 774 VITNLQPETAYSITVAAYTMKGDGARSKPKVVV-TKGAVLGRPTLSVQQT--PEGSLLAR 830
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P P + Y++ + R S VH +TY + ++
Sbjct: 831 WEP-PAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVF-----RL 884
Query: 405 QAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKL 463
A + G G E+ EV++I ED P+ PQ++ A N++A V + G +
Sbjct: 885 AARSPGGLGEEAAEVLSI--PEDTPRGHPQILEAAG-NASAGTVLLRWLPPVPAERNGAI 941
Query: 464 IGHRLKYWKQ-----ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
+ + + + + E LSR R L GL+PDT Y ++V A G GP
Sbjct: 942 VKYTVAVREAGALGPARETELPAGRLSRARRTLTL-QGLKPDTAYDLQVRAHTRRGPGPF 1000
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S RTF + Q P + V T++ + W + P N P YK++ L D+
Sbjct: 1001 SPPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 1056
Score = 31.9 bits (69), Expect = 7.6
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PRF+++ +I F+ C A DP WN G ++ +S + + G
Sbjct: 33 PRFIKEPKDQIGVSGRVASFV-CQATGDP--KPRVTWNKKGKKV-NSQRFETIEFDESAG 88
Query: 178 GELTIYNVSLS-DVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L I + D YECV ++++G I+ H +L + P G
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 128 bits (308), Expect = 8e-29
Identities = 135/592 (22%), Positives = 243/592 (41%), Gaps = 58/592 (9%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGG-----KRFITEN-------GNLIIRQLSRDDEG 93
T+ C P P TW KD + + K+ +E+ G L I Q D+G
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQG 203
Query: 94 VYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRIT-------AQVNSVVFLHCNADVDP 146
Y CVA N GT S + +R R + ++PPR + V + C A P
Sbjct: 204 KYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 263
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ ++ L +D D+ + + + L + +V S +Y CV S +G I +
Sbjct: 264 MPYVKWMLGAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEA 313
Query: 207 HVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISE 266
Q+ ++ P PPG + +S+TL W + N P++ Y++ + + Y +
Sbjct: 314 IAQITVKPLPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---K 368
Query: 267 NIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYE 326
I V RY+ L P++ YEFR+ A+N +G G PS P TS P
Sbjct: 369 EIDGV-ATTRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSS 419
Query: 327 APANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGT 386
AP +V + + + W P NG Y++++ + ++ + K+ +
Sbjct: 420 APRDVQARMLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADS 474
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALN 446
+ I + Y VKV AF IG GP S + + + +P P A + T++
Sbjct: 475 QITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSIL 533
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
++W P + + L Y E+ EE+ I T+ + GL+P++ YY +
Sbjct: 534 LSWTPPRSD------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFR 584
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+ A + G G + RT + P PP ++ + T++ V W+ + +
Sbjct: 585 LAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITE 644
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
Y ++ +D + ++ + + + + Y + V A+++ G G
Sbjct: 645 YSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPG 696
Score = 125 bits (302), Expect = 4e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KPLPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
Score = 46.4 bits (105), Expect = 3e-04
Identities = 55/208 (26%), Positives = 88/208 (42%), Gaps = 27/208 (12%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRI 212
SD G YECV ++ G R S+ L +
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYV 225
>BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein.
Length = 1329
Score = 127 bits (307), Expect = 1e-28
Identities = 111/418 (26%), Positives = 188/418 (44%), Gaps = 27/418 (6%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYML---TGRTHWNSTWYVISENIPNVM 272
PGPP + I I SVTL++ I+ +++ G W +I + + N
Sbjct: 169 PGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQ-LSN-- 225
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
E D R+ L P+ Y FR++ +NI+G PS PS + T P APANVS
Sbjct: 226 EPDA-----RSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVS 280
Query: 333 GGGGKTGDLTITWTPLPTSLQNG--PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
L + W PLP NG + YKI + R+ + S +++ +
Sbjct: 281 LRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIED 340
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ +T Y V+VQAFN IG GP S+ V + E +P P VSA + S+++ V W+
Sbjct: 341 LEE---WTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWS 397
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
+ ++ G ++G+++ Y ++++ + + + + A + GL Y V+V+AF
Sbjct: 398 EVPEADR--NGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAF 455
Query: 511 NSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
G+G P LERT P PP + T++R++W+ P +L Y++
Sbjct: 456 TRIGDGSPSHPPILERTLDDVP-GPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQI 512
Query: 570 --RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
RL + +T + + P + A + + P Y R+ A + G G + +
Sbjct: 513 THRLNTTTANTATV-EVLAPSARQYTA--TGLKPESVYLFRITAQTRKGWGEAAEALV 567
Score = 111 bits (267), Expect = 8e-24
Identities = 90/346 (26%), Positives = 149/346 (43%), Gaps = 16/346 (4%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
PP P VQ ++ SV L W + P+ Y + R + W + S ++ +
Sbjct: 578 PPSRPM-VQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSH---- 632
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
+ + L P+ Y+FR++A N +G + S S +T P EAP +S
Sbjct: 633 -----NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVT 687
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISST 394
T + I W P NG + ++I +R E + +L+ N G ++
Sbjct: 688 PHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYE-GLRGFMLRGINNPGATWAELTYL 746
Query: 395 YFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQ 454
+ Y++++ +N +G GP S ++ E +P AP+ V +T L+VTW P
Sbjct: 747 NKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP--P 804
Query: 455 SRERLRGKLIGHRLKYWK-QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSA 513
+ G + G+++ +W+ Q E + L N + L T Y V V AFN+A
Sbjct: 805 PLDSQNGDIQGYKIYFWEAQRGNLTERVKTLF-LAENSVKLKNLTGYTAYMVSVAAFNAA 863
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTN 559
G+GP S +T + AP P+SV T++ V W Q N
Sbjct: 864 GDGPRSTPTQGQTQQAAP-SAPSSVKFSELTTTSVNVSWEAPQFPN 908
Score = 108 bits (259), Expect = 7e-23
Identities = 103/416 (24%), Positives = 175/416 (42%), Gaps = 18/416 (4%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
E PGP G + I +S+ + W + +TGY ++ +N T ++ +PNV
Sbjct: 68 EDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWE-EYNRTNTRVTHYLPNVT 126
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
R G T TT Y + A+ G GQ SA + + P P N+
Sbjct: 127 LEYRVTG---LTALTT------YTIEVAAMTSKGQGQVSASTISSGVPPELP-GPPTNL- 175
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQS-LLLKKYGN-IGTYVVH 390
G G ++T P I + + G E + LL+ + N +
Sbjct: 176 -GISNIGPRSVTLQFRP-GYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSME 233
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVV-TIYSAEDMPQVAPQLVSARSFNSTALNVTW 449
+ +T Y +++ N +G P S+ I + + P +AP VS R+ + T+L + W
Sbjct: 234 VPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRW 293
Query: 450 NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMA 509
P+ + + +G+++KY + + + + + I L+ T Y V+V A
Sbjct: 294 MPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 353
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
FN+ G GP S+ + RT P P +V+ A +++ V W V + +LGYKV
Sbjct: 354 FNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKV 413
Query: 570 RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
E D D + +V A ++ + Y ++VLA++ GDG S P I
Sbjct: 414 MYKEKDSD-TQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPI 468
Score = 104 bits (250), Expect = 9e-22
Identities = 98/419 (23%), Positives = 177/419 (42%), Gaps = 25/419 (5%)
Query: 212 IEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
++ PGPP G+ ++ +SV L W + I Y +T R ++ N
Sbjct: 473 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR---------LNTTTANT 523
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN- 330
V+ R +T L P ++Y FRI A G G+ + + D+P + P+
Sbjct: 524 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRP-QPPSRP 582
Query: 331 -VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
V + + ++W P L P +Y I R S + N +++V
Sbjct: 583 MVQQEDVRARSVLLSWEPGSDGL--SPVRYYTIQTRELPSG-RWALHSASVSHNASSFIV 639
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+T Y +V+A NDIG S E ++ + + P AP ++S +T++ +
Sbjct: 640 DRLKP--FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 697
Query: 449 WNPIDQSRERLRGKLIGHRLKYWK--QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
W P + +++ G L+G R++Y + E + ++ WA + L Y ++
Sbjct: 698 WQP--PAEDKINGILLGFRIRYRELLYEGLRGFMLRGINNPGATWAELTYLNKHRRYEIR 755
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+ +N+ GEGP S P P +V V T L V W ++ + G
Sbjct: 756 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQG 815
Query: 567 YKVRLWELDQ-DMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
YK+ WE + +++ T+ E+ ++ + N+ +Y + V A++ GDG S+PT
Sbjct: 816 YKIYFWEAQRGNLTERVKTLFLAENSVK--LKNLTGYTAYMVSVAAFNAAGDGPRSTPT 872
Score = 88.2 bits (209), Expect = 8e-17
Identities = 76/332 (22%), Positives = 140/332 (42%), Gaps = 13/332 (3%)
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
W Y ++QA N +G G P + + T P P NVS + + + W+ +P +
Sbjct: 344 WTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 402
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
+NG + YK+ ++ S+ + + L++ GN + ++ Y Y+V+V AF IG
Sbjct: 403 DRNGLVLGYKVMYKEKDSDTQPRFWLVE--GN-SSRSAQLTGLGKYVLYEVQVLAFTRIG 459
Query: 412 PG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
G P + + +D+P P + +T++ + W P + I HRL
Sbjct: 460 DGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 518
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKA 530
E L+ + R + GL+P++ Y ++ A G G +E + T ++
Sbjct: 519 TTANTATVEV---LAPSARQYTA-TGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD 574
Query: 531 PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEH 590
+PP+ V D V+ + ++ P+ Y ++ EL + + H
Sbjct: 575 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHS--ASVSH 632
Query: 591 KLEAYI-SNIIPGKSYNLRVLAYSNGGDGRMS 621
++I + P SY RV A ++ GD S
Sbjct: 633 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 664
Score = 88.2 bits (209), Expect = 8e-17
Identities = 89/336 (26%), Positives = 137/336 (40%), Gaps = 21/336 (6%)
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
YE R+ N +G G PS+P + P AP NV G L +TW P P QN
Sbjct: 752 YEIRMSVYNAVGEG-PSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQN 810
Query: 355 GPGIHYKI-FWR-RNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
G YKI FW + G+ E L + V + + YT Y V V AFN G
Sbjct: 811 GDIQGYKIYFWEAQRGNLTERVKTLF-----LAENSVKLKNLTGYTAYMVSVAAFNAAGD 865
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWK 472
GP S + + P AP V +T++NV+W ++ + G L G+RL Y
Sbjct: 866 GPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNVSW----EAPQFPNGILEGYRLVYEP 920
Query: 473 ---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + + + W + L Y ++ A + GPE E + +
Sbjct: 921 CSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGE 979
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE 589
PP V + + + + W P + P+ Y + D+ + +P E
Sbjct: 980 GAPGPPG-VPIIVRYSSAIAIHWSSGDPG--KGPITRYVIEARPSDEGLWDILIKDIPKE 1036
Query: 590 HKLEAYISNII-PGKSYNLRVLAYSNGGDGRMSSPT 624
+ +I+ PG SY+ RV+A ++ G G SSP+
Sbjct: 1037 VSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 1072
Score = 61.7 bits (143), Expect = 8e-09
Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PGPPG V I+ S++ + W+ + PIT Y++ R W ++ ++IP
Sbjct: 979 EGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPK-- 1035
Query: 273 EVDRYNGRKRATVSTTLL-PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
EV Y T S +L P Y+FR+ A+N G G PS+PS P+
Sbjct: 1036 EVSSY------TFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPF 1083
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/165 (26%), Positives = 79/165 (47%), Gaps = 8/165 (4%)
Query: 465 GHRLKYWKQENKEEECIYYLS---RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESER 521
G++L W+ E +EE + + + + + GL+ T Y+ V+ F + G+GP S
Sbjct: 2 GYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTP 61
Query: 522 YLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTA 581
L RT P P ++ T+L+V W+ +P + L GY++ WE +T
Sbjct: 62 QLVRTHEDVP-GPVGHLSFSEILDTSLKVSWQ--EPGEKNGILTGYRIS-WEEYNRTNTR 117
Query: 582 NDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
+P LE ++ + +Y + V A ++ G G++S+ TI+
Sbjct: 118 VTHYLP-NVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 161
Score = 51.6 bits (118), Expect = 9e-06
Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 8/168 (4%)
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALN 446
+V +S +T Y V F G GP S + + ED+P L S T+L
Sbjct: 30 HVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHL-SFSEILDTSLK 88
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECI-YYLSRTTRNWALIVGLQPDTYYYV 505
V+W Q G L G+R+ W++ N+ + +YL T + + GL T Y +
Sbjct: 89 VSW----QEPGEKNGILTGYRIS-WEEYNRTNTRVTHYLPNVTLEYR-VTGLTALTTYTI 142
Query: 506 KVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWR 553
+V A S G+G S + PP ++ + P ++ + +R
Sbjct: 143 EVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR 190
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 126 bits (303), Expect = 3e-28
Identities = 161/660 (24%), Positives = 268/660 (40%), Gaps = 74/660 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P S +Y++ + ++G E Q + ++ + + +S Y++ ++ A
Sbjct: 538 P-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKPNSLYYF-----RLAA 587
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ G G + ++ + + P PQ +S S +ST++ V+W P E+ G + +
Sbjct: 588 RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP--PPVEKQNGIITEY 645
Query: 467 RLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
+KY +++K E + S TT+ L+ L+ T Y + V A G GPES L
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVTAHTDVGPGPESLSVL 703
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
RT P PP V V A + T+++V WR P + + GY+V ++
Sbjct: 704 IRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQP 763
Query: 584 TIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIG 630
+ + EH + IS + P SY+L V AY+ GDG S P + G
Sbjct: 764 MLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTG 821
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 575 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 633
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 634 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 691
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 692 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 748
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 749 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 808
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 809 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 864
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 865 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 711 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 769
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 770 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 828
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 829 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 884
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 885 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 938
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 939 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 995
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 996 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 1051
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 1052 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 1094
>AF464063-1|AAN86141.1| 282|Homo sapiens contactin 4a protein.
Length = 282
Score = 125 bits (302), Expect = 4e-28
Identities = 81/262 (30%), Positives = 133/262 (50%), Gaps = 16/262 (6%)
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALN 446
YV S + ++P++VKV FN+ G GP S +YSAE+ P P + ARS ++T +
Sbjct: 16 YVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIE 75
Query: 447 VTW-NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYV 505
V W +P+ E+ RG++ G+ +KYW+ E+KEE + + I L+ Y++
Sbjct: 76 VFWASPL----EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHL 131
Query: 506 KVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLL 565
V A+NSAG GP S T + P +PP ++ +W + + + W V+ + E +
Sbjct: 132 AVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVK 190
Query: 566 GYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
GYKV L+ ++ ST+ IE + ++ + Y + + +S+GGDG S
Sbjct: 191 GYKV-LYRWNRQSSTS-----VIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIR 244
Query: 626 AFQIGDYHSEAYGYYARGSTSN 647
+I S AY + STSN
Sbjct: 245 IPKI----SNAYARGSGASTSN 262
>AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein.
Length = 1471
Score = 124 bits (300), Expect = 8e-28
Identities = 109/420 (25%), Positives = 187/420 (44%), Gaps = 31/420 (7%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHW---NSTWYVI--SENIPN 270
PG P + I I S TL++ I+ +++ G+ W + EN P+
Sbjct: 348 PGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPD 407
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
++ N L P+ Y FR++ +NI+GP S S T P AP +
Sbjct: 408 AQMLEIPN----------LTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTS 457
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNG--PGIHYKI-FWRRNGSEVEFQSLLLKKYGNIGTY 387
V+ L + W PLP S NG + Y+I +WR + ++ + T
Sbjct: 458 VTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFT- 516
Query: 388 VVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNV 447
I + Y++++QAFN +G GP SEVV + E +P AP+ VSA + +ST + +
Sbjct: 517 ---IEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILL 573
Query: 448 TWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
TW + + + G ++G+++ + ++ E + + AL+ GL+ Y ++V
Sbjct: 574 TWTSVPEQDQ--NGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQV 631
Query: 508 MAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+AF G G P + LERT AP PP + T++R+VW+ P +LG
Sbjct: 632 LAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQ--PPEEPNGIILG 688
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
Y++ + L S T V + + + +++ P +Y R+ A + G G T+
Sbjct: 689 YQI-AYRL-ASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATV 746
Score = 120 bits (289), Expect = 2e-26
Identities = 102/400 (25%), Positives = 164/400 (41%), Gaps = 19/400 (4%)
Query: 216 PGPPGGVQI--LGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PP + + + S+ L+W + PI + + R W S +I +
Sbjct: 755 PAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISH--- 811
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
A V L P+ Y+ R++A N +G S+ + +T D P E P +VS
Sbjct: 812 ------EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSA 865
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISS 393
T + I W P NG Y+I++R E K N ++
Sbjct: 866 TPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAG-SGTEAKTLKNPIALRAELTD 924
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPID 453
Y Y+V + A+N IG P S V ++ E P +APQ V ++ L VTW+P
Sbjct: 925 LKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP-- 982
Query: 454 QSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSA 513
E G + G+++ YW+ +++ E + + L T Y V + AFN+A
Sbjct: 983 PPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAA 1042
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
G+GP+S+ RT + AP P+ + TTL V W +P L GY+V
Sbjct: 1043 GDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWG--EPAAANGILQGYRVVYEP 1099
Query: 574 LDQDMSTANDTIVPIEHKLEAY--ISNIIPGKSYNLRVLA 611
L + V + + + + ++ G +Y RV A
Sbjct: 1100 LAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 1139
Score = 113 bits (271), Expect = 3e-24
Identities = 88/341 (25%), Positives = 151/341 (44%), Gaps = 14/341 (4%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P Y+FR+ A+N +G GQ SA + + + P P N+ G + + W P
Sbjct: 11 LTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPP 70
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P + NG Y + +R G E+Q + + ++ +T Y+++V A+N
Sbjct: 71 PETEHNGVLRGYILRYRLAGLPGEYQQ---RNITSPEVNYCLVTDLIIWTQYEIQVAAYN 127
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
G G S VT Y+ + +P PQ V + NST + WNP Q + + G G++L
Sbjct: 128 GAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQ--QFINGINQGYKL 185
Query: 469 KYWKQENKEEECIYYLSRTTR--NWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
W + E + ++ + I L+ T Y+ V+ F + G+GP S L T
Sbjct: 186 LAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWT 245
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWEL-DQDMSTANDTI 585
P ++ T+L+V W+ +P + + GY++ WE+ ++ S T+
Sbjct: 246 QEDKP-GAVGHLSFTEILDTSLKVSWQ--EPLEKNGIITGYQIS-WEVYGRNNSRLTHTL 301
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
H E I + +Y + V A + G G ++S TI+
Sbjct: 302 NSTTH--EYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTIS 340
Score = 101 bits (243), Expect = 6e-21
Identities = 110/430 (25%), Positives = 189/430 (43%), Gaps = 29/430 (6%)
Query: 205 SSHVQLRIEGPPG-PPGGVQILGIQRSSVTLEWT---DSNSNGRPIT-GYMLTGRTHWNS 259
SS V ++ PP P V + +S+ L W DS NG P + GY + +W S
Sbjct: 440 SSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPESVGYRIK---YWRS 496
Query: 260 TWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFST 319
+ S + V+ DR +R L W YE ++QA N +G G P + + T
Sbjct: 497 D--LQSSAVAQVVS-DRL---EREFTIEELEEWMEYELQMQAFNAVGAG-PWSEVVRGRT 549
Query: 320 SGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLK 379
P AP NVS + + +TWT +P QNG + YKI +R + E +S +++
Sbjct: 550 RESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVR 609
Query: 380 KYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPG-PESEVVTIYSAEDMPQVAPQLVSAR 438
GN T ++ + Y+++V AF IG G P + ++ + +D P +LV
Sbjct: 610 --GN-HTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPE 666
Query: 439 SFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQ 498
T++ + W P ++ + G I +RL + + T R + L
Sbjct: 667 -VRLTSVRIVWQPPEEPNGIILGYQIAYRLA---SSSPHTFTTVEVGATVRQFTA-TDLA 721
Query: 499 PDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPT 558
P++ Y ++ A G G E + T ++ PP + V + T + ++V +
Sbjct: 722 PESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGS 781
Query: 559 NEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEA-YISNIIPGKSYNLRVLAYSNGG 616
+ P+ + +++ EL + + T + +I H+ A + + P SY LR+ A ++ G
Sbjct: 782 DGASPIRYFTMQVRELPRGEWQTYSSSI---SHEATACVVDRLRPFTSYKLRLKATNDIG 838
Query: 617 DGRMSSPTIA 626
D SS T A
Sbjct: 839 DSDFSSETEA 848
Score = 85.0 bits (201), Expect = 8e-16
Identities = 62/232 (26%), Positives = 104/232 (44%), Gaps = 8/232 (3%)
Query: 400 YDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y +V A N++G G S E + E+ P P+ + A + ++ V W P ++
Sbjct: 17 YQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHN 76
Query: 459 --LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
LRG ++ +RL E ++ ++ N+ L+ L T Y ++V A+N AG G
Sbjct: 77 GVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLG 132
Query: 517 PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
S E T + P PP +V A + TT++ +W GYK+ W D
Sbjct: 133 VFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADA 192
Query: 577 DMSTANDTIVPIEHKLE-AYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAF 627
+ TI P H + +I+N+ +Y VL ++ GDG S+P + +
Sbjct: 193 PEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVW 244
Score = 84.2 bits (199), Expect = 1e-15
Identities = 103/420 (24%), Positives = 166/420 (39%), Gaps = 30/420 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGR-THWNSTWYVISENIPN 270
P PPG V SSV ++W D + NG + GY + R + + ++ + N
Sbjct: 856 PGEPPGSVSATPHTTSSVLIQWQPPRDESLNGL-LQGYRIYYRELEYEAGSGTEAKTLKN 914
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
+ + RA + T L + YE + A NI+G SAP F P AP N
Sbjct: 915 PIAL-------RAEL-TDLKKYRRYEVIMTAYNIIGESPASAPVEVF-VGEAAPAMAPQN 965
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
V L +TW P P QNG YKI++ S+ E + + K + VV
Sbjct: 966 VQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKM---KVLFLPEPVVR 1022
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ + +T Y V + AFN G GP+S+ + + P AP ++ ST LNV+W
Sbjct: 1023 LKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG-APSFLAFSEITSTTLNVSWG 1081
Query: 451 PIDQSRERLRGKLIGHRLKY---WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
G L G+R+ Y + + + + W + L Y+ +V
Sbjct: 1082 ----EPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRV 1137
Query: 508 MAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGY 567
A + GPE + + + P V V + L + W + + + P GY
Sbjct: 1138 QA-RTITYGPELQANITAGPAEGSPGSPRDVLV-TKSASELTLQW--TEGHSGDTPTTGY 1193
Query: 568 KVRLWELDQDMSTANDTIVP-IEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
+ D+ + +P + + G +Y RV+A + G G S+P+ A
Sbjct: 1194 VIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTA 1253
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P V + S +TL+WT+ +S P TGY++ R W + ++IP
Sbjct: 1158 EGSPGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPR-- 1214
Query: 273 EVDRYNGRKRATVSTTLLPWAI-YEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
Y T+S L + YEFR+ A+N G G+PS PS S + P+
Sbjct: 1215 SATSY------TLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 1262
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 123 bits (296), Expect = 2e-27
Identities = 146/648 (22%), Positives = 259/648 (39%), Gaps = 62/648 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL---SLKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A+N + A+L VL L F + + E T+ C P
Sbjct: 104 VYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPD 163
Query: 57 PTFTWKKDNIVIGAGG-----KRFITEN-------GNLIIRQLSRDDEGVYTCVAKNQYG 104
P TW KD + + K+ +E G L I D+G Y CVA N G
Sbjct: 164 PEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVATNSAG 223
Query: 105 TDESRGRLIVLRAPRFLEKLPPRITA-QVNSVVFLHCNADVDPIL---DTAYL-WNHNGL 159
S + +R R + ++ PR + ++ + N ++ + Y+ W
Sbjct: 224 VRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAE 283
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
+ D+ V + + ELT + D +Y CV S++G I + Q+ ++ P P
Sbjct: 284 DLTPEDDMPVGRNVL----ELT----DVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAP 335
Query: 220 GGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNG 279
G + +S+T+ W N + P++ Y++ ++ Y I E+I RY+
Sbjct: 336 GTPMVTENTATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS- 388
Query: 280 RKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTG 339
L P + YE + A+N +G G PS S T P AP NV
Sbjct: 389 ------IGGLSPNSEYEIWVSAVNSIGQGPPSE-SVVTRTGEQAPASAPRNVQARMLSAT 441
Query: 340 DLTITWT-PL-PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY 397
+ + W P+ P L G ++Y + E E +K+ + + + S
Sbjct: 442 TMIVQWEEPVEPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLED 494
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
Y V+V AF +G GP S+ + + + + +P P + A + + T++ ++W+P Q
Sbjct: 495 ETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE-- 551
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
+I + L + + ++ E + T+ ++ L+P+T Y ++ A + G G
Sbjct: 552 ----SIIKYELLFREGDHGREVGRTFDPTTSY---VVEDLKPNTEYAFRLAARSPQGLGA 604
Query: 518 ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD 577
+ +RT + P PP V + T + V WR P L+GY VR L +
Sbjct: 605 FTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSE 664
Query: 578 MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
+ + + + Y + +A++ G G SSP +
Sbjct: 665 DPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVV 712
Score = 116 bits (278), Expect = 4e-25
Identities = 167/662 (25%), Positives = 268/662 (40%), Gaps = 78/662 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YSS A L V L+ P F P+ E GGNV + C +
Sbjct: 214 YECVATNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIM--PGGNVNITCVAVGS 271
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + + + N ++ D YTCVA + G E+ ++ V
Sbjct: 272 PMPYVKWMQGAEDLTPEDDMPVGRN---VLELTDVKDSANYTCVAMSSLGVIEAVAQITV 328
Query: 115 LRAPRFLEKLPPRITAQV-NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
P+ P +T S+ + + DP+ + Y+ + K Y +I
Sbjct: 329 KSLPK--APGTPMVTENTATSITITWDSGNPDPV--SYYVIEYKS---KSQDGPY---QI 378
Query: 174 KIDGGELTIYNVS-LSDVGDYECVVKS--AIGR--ISSHVQLRI--EGPPGPPGGVQILG 226
K D T Y++ LS +YE V + +IG+ S V R + P P VQ
Sbjct: 379 KEDI-TTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARM 437
Query: 227 IQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATV 285
+ +++ ++W + I GY + +Y + P V ++N T
Sbjct: 438 LSATTMIVQWEEPVEPNGLIRGYRV---------YYTMEPEHP-VGNWQKHNVDDSLLTT 487
Query: 286 STTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW 345
+LL Y R+ A +G G S P Q T P + P N+ +T++W
Sbjct: 488 VGSLLEDETYTVRVLAFTSVGDGPLSDPI-QVKTQQGVPGQ-PMNLRAEARSETSITLSW 545
Query: 346 TPLPTSLQNGPGIHYKIFWRR--NGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVK 403
+P P + I Y++ +R +G EV + + +YVV T Y +
Sbjct: 546 SP-P---RQESIIKYELLFREGDHGREVG------RTFDPTTSYVVEDLKPN--TEYAFR 593
Query: 404 VQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKL 463
+ A + G G + VV + + P PQ V S STA+ V+W P E G L
Sbjct: 594 LAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRP--PPPETHNGAL 651
Query: 464 IGHRLKYWK--QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESER 521
+G+ ++Y E+ E + + + TT L+ L+ T Y + +A G GPES
Sbjct: 652 VGYSVRYRPLGSEDPEPKEVNGIPPTTTQ-ILLEALEKWTQYRITTVAHTEVGPGPESSP 710
Query: 522 YLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD------ 575
+ RT P PP V A + T +RV+W P + + GY+V ++
Sbjct: 711 VVVRTDEDVPSAPPRKVEAEALNATAIRVLWLGPVPGRQHGQIRGYQVHYVRMEGAEGRG 770
Query: 576 ----QDMSTAN---DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQ 628
+D+ A+ +T E+ E I+N+ P +Y++ V AY+ GDG S P +
Sbjct: 771 PPRIKDVMLADAQWETDDTAEY--EMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVT 828
Query: 629 IG 630
G
Sbjct: 829 KG 830
Score = 52.0 bits (119), Expect = 7e-06
Identities = 88/428 (20%), Positives = 166/428 (38%), Gaps = 40/428 (9%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P PP V+ + ++ +++ + W ++ + GY + R + P
Sbjct: 618 PSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRP--------LGSEDPEPK 669
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
EV+ + L W Y A +GPG S+P T D P P V
Sbjct: 670 EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVV-VRTDEDVPSAPPRKVE 728
Query: 333 GGGGKTGDLTITWT-PLPTSLQNGPGIHYKIFW-RRNGSE----VEFQSLLLK----KYG 382
+ + W P+P Q+G Y++ + R G+E + ++L +
Sbjct: 729 AEALNATAIRVLWLGPVP-GRQHGQIRGYQVHYVRMEGAEGRGPPRIKDVMLADAQWETD 787
Query: 383 NIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNS 442
+ Y + I++ T Y + V A+ G G S+ + + + + +S +
Sbjct: 788 DTAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAV--LGRPTLSVQQTPE 845
Query: 443 TALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTY 502
+L W P + E +++G+RL++ ++++ + + R A G+
Sbjct: 846 GSLLARWEPPAGTAE---DQVLGYRLQFGREDSTPLATLEFPPSEDRYTAS--GVHKGAT 900
Query: 503 YYVKVMAFNSAGEGPESERYL---ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTN 559
Y ++ A + G G E+ L E T R PQ A+ N A T+ + W P
Sbjct: 901 YVFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAG---TVLLRWLPPVPAE 957
Query: 560 EEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY----ISNIIPGKSYNLRVLAYSNG 615
++ Y V + E + A +T +P + A + + P +Y+L+V A++
Sbjct: 958 RNGAIVKYTVAVREAGA-LGPARETELPAAAEPGAENAVTLQGLKPDTAYDLQVRAHTRR 1016
Query: 616 GDGRMSSP 623
G G S P
Sbjct: 1017 GPGPFSPP 1024
Score = 51.6 bits (118), Expect = 9e-06
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 27/208 (12%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT----ENGN 81
P F K P + G GG + C+ PKP TW K + + +RF T E+
Sbjct: 33 PRFIKEPKD--QIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNS--QRFETIEFDESAG 88
Query: 82 LIIR-QLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
++R Q R DE VY CVA+N G +L VLR + P P++ +
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID-------GGELTIYNV 185
+ C A +P D W + L + S+ K+++ + G L I +
Sbjct: 149 TRTATMLCAASGNP--DPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESS 206
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRI 212
+D G YECV ++ G R SS L +
Sbjct: 207 EETDQGKYECVATNSAGVRYSSPANLYV 234
Score = 42.3 bits (95), Expect = 0.005
Identities = 72/299 (24%), Positives = 112/299 (37%), Gaps = 21/299 (7%)
Query: 285 VSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTIT 344
V T L P Y + A + G G S P T G +V G L
Sbjct: 795 VITNLQPETAYSITVAAYTMKGDGARSKPKVVV-TKGAVLGRPTLSVQQT--PEGSLLAR 851
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P P + Y++ + R S VH +TY + ++
Sbjct: 852 WEP-PAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVF-----RL 905
Query: 405 QAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKL 463
A + G G E+ EV++I ED P+ PQ++ A N++A V + G +
Sbjct: 906 AARSRGGLGEEAAEVLSI--PEDTPRGHPQILEAAG-NASAGTVLLRWLPPVPAERNGAI 962
Query: 464 IGHRLKYWKQ----ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPES 519
+ + + + +E E N + GL+PDT Y ++V A G GP S
Sbjct: 963 VKYTVAVREAGALGPARETELPAAAEPGAENAVTLQGLKPDTAYDLQVRAHTRRGPGPFS 1022
Query: 520 ERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
RTF + Q P + V T++ + W + P N P YK++ L D+
Sbjct: 1023 PPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 1077
Score = 31.9 bits (69), Expect = 7.6
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PRF+++ +I F+ C A DP WN G ++ +S + + G
Sbjct: 33 PRFIKEPKDQIGVSGGVASFV-CQATGDP--KPRVTWNKKGKKV-NSQRFETIEFDESAG 88
Query: 178 GELTIYNVSLS-DVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L I + D YECV ++++G I+ H +L + P G
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 118 bits (283), Expect = 9e-26
Identities = 147/590 (24%), Positives = 241/590 (40%), Gaps = 79/590 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A+N + + +SA L V S P F P + + G VT +C+ P+P
Sbjct: 289 YTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVV--ALGRTVTFQCEATGNPQPAI 346
Query: 60 TWKKD---NIVIG----AGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGR 111
W+++ N++ RF +++ G+L I + R D G Y C N G+ ++
Sbjct: 347 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 406
Query: 112 LIVL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
L V R P + + P T V+ L C A P+ LW +G+ +
Sbjct: 407 LEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGVLVSTQ-- 462
Query: 167 LYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQLRIEG----PPGP- 218
+ RIK ++ G L I L D G Y C+ + G S++++++ G PP P
Sbjct: 463 ---DSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPT 519
Query: 219 --------PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWN-STWYVISENIP 269
P ++ + R++VTL W + ++G T Y++ +H + S+W ++EN+
Sbjct: 520 DPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK 579
Query: 270 NVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA 329
E G K P AIY F ++A N G PS S T P
Sbjct: 580 T--ETSAIKGLK---------PNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGV 628
Query: 330 NVSGGGGKTGDLTITWTPLPTSLQNGP-GIH------------YKIFWRRNGSEVEFQSL 376
+ + G+ + PT L + +H YKI +R +G+
Sbjct: 629 DHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDW 687
Query: 377 LLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ--L 434
L+ + V I Y++K + F + G +SE+ + E+ P PQ
Sbjct: 688 LVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVT 747
Query: 435 VSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL- 493
VS N TA+ V+W P + + G + K W N E Y++++T L
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQ--NGMV--QEYKVWCLGN---ETRYHINKTVDGSTLS 800
Query: 494 --IVGLQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNV 540
I L P Y V+V A AG G +SE ++++ P P V++
Sbjct: 801 VVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSL 850
Score = 108 bits (259), Expect = 7e-23
Identities = 150/651 (23%), Positives = 253/651 (38%), Gaps = 48/651 (7%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C N + S A+L VL +PSF K P L + KC+ P PT
Sbjct: 199 YVCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTVDDSAE--FKCEARGDPVPTVR 255
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL---RA 117
W+KD+ + + I ++ L IR+++ D G YTCVA+N G E+ L V
Sbjct: 256 WRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKI 175
P F+ K ++ A +V F C A +P A W G + + + R +
Sbjct: 315 PHFVVKPRDQVVALGRTVTF-QCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSV 371
Query: 176 DG-GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG--PPGPPGGVQILGIQRSSV 232
G+LTI NV SDVG Y C + G I + L + PP ++ G +V
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTV 430
Query: 233 TLEWT---DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY-----NGRKRAT 284
++ T + G P+ + ST + + N + RY GR
Sbjct: 431 AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 490
Query: 285 VSTTL--LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
ST W+ Y +Q + P QP P T + AP+ +T
Sbjct: 491 ASTPSGEATWSAY-IEVQEFGV--PVQPPRP-----TDPNLIPSAPSKPEVTDVSRNTVT 542
Query: 343 ITWTP------LPTSLQNGPGIHYK-IFWRRNGSEVEFQSLLLK--KYGNIGTYVVHISS 393
++W P PTS H W+ V+ ++ +K K I ++V ++
Sbjct: 543 LSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAAN 602
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAE-DMPQVAPQLVSARSFNSTALNVTWNPI 452
Y + P S+ V + ++ L + +S+++ V W +
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT-V 661
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
DQ + ++G I +R + + ++ + +N +I L+ Y +K F +
Sbjct: 662 DQQSQYIQGYKILYR-PSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFN 720
Query: 513 AGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLW 572
+G +SE +T +AP PP V V +D ++ + P + + + + ++W
Sbjct: 721 EFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVW 780
Query: 573 ELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
L + + V L I ++PG Y++ V A + G G S P
Sbjct: 781 CLGNETRYHINKTVD-GSTLSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/222 (28%), Positives = 99/222 (44%), Gaps = 14/222 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
+Y C A+N L + S +A L V L+ F+++P ++ E ++C+P P+PT
Sbjct: 105 VYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVVGEPA--VMECQPPRGHPEPT 162
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESR-GRLIVLRA 117
+WKKD + +R G L+I + D G Y CV N G ES L VL
Sbjct: 163 ISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER 222
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+ K P + V+ C A DP+ W KD +L ++ D
Sbjct: 223 PSFV-KRPSNLAVTVDDSAEFKCEARGDPV--PTVRWR------KDDGELPKSRYEIRDD 273
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I V+ D+G Y CV ++ +G+ + L ++ PP
Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 68.5 bits (160), Expect = 7e-11
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 19/205 (9%)
Query: 15 SSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG--- 71
S ++LR P +HP +L S+G TL CK E P PT W K +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIV--SKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDD 75
Query: 72 --GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEK 123
R + +G+L ++ SR DEGVY CVA+N G S + + R +
Sbjct: 76 PRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQ 135
Query: 124 LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIY 183
P + V + C + W +G + D ++RI I GG+L I
Sbjct: 136 NPSDVMVVVGEPAVMECQPPRGH-PEPTISWKKDGSPLDDK-----DERITIRGGKLMIT 189
Query: 184 NVSLSDVGDYECVVKSAIGRISSHV 208
SD G Y CV + +G S V
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEV 214
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 118 bits (283), Expect = 9e-26
Identities = 146/589 (24%), Positives = 245/589 (41%), Gaps = 77/589 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A+N + + +SA L V S P F P + + G VT +C+ P+P
Sbjct: 289 YTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVV--ALGRTVTFQCEATGNPQPAI 346
Query: 60 TWKKD---NIVIG----AGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGR 111
W+++ N++ RF +++ G+L I + R D G Y C N G+ ++
Sbjct: 347 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 406
Query: 112 LIVL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
L V R P + + P T V+ L C A P+ LW +G+ +
Sbjct: 407 LEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGVLVSTQ-- 462
Query: 167 LYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQLRIEG----PPGP- 218
+ RIK ++ G L I L D G Y C+ + G S++++++ G PP P
Sbjct: 463 ---DSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPT 519
Query: 219 --------PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWN-STWYVISENIP 269
P ++ + R++VTL W + ++G T Y++ +H + S+W ++EN+
Sbjct: 520 DPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK 579
Query: 270 NVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA 329
E G K P AIY F ++A N G PS S T P
Sbjct: 580 T--ETSAIKGLK---------PNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGV 628
Query: 330 NVSGGGGKTGDLTI-TWTPL---PTSL-------QNGPGIH-YKIFWRRNGSEVEFQSLL 377
+ + G+ + P P+S+ Q I YKI +R +G+ L
Sbjct: 629 DHKQVQRELGNAVLHLHNPTVLSPSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWL 688
Query: 378 LKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ--LV 435
+ + V I Y++K + F + G +SE+ + E+ P PQ V
Sbjct: 689 VFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTV 748
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTT--RNWAL 493
S N TA+ V+W P + + G + K W N E Y++++T +++
Sbjct: 749 SKNDGNGTAILVSWQPPPEDTQ--NGMV--QEYKVWCLGN---ETRYHINKTVDGSTFSV 801
Query: 494 IVG-LQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNV 540
++ L P Y V+V A AG G +SE ++++ P P V++
Sbjct: 802 VIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSL 850
Score = 105 bits (251), Expect = 7e-22
Identities = 154/655 (23%), Positives = 252/655 (38%), Gaps = 56/655 (8%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C N + S A+L VL +PSF K P L + KC+ P PT
Sbjct: 199 YVCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTVDDSAE--FKCEARGDPVPTVR 255
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL---RA 117
W+KD+ + + I ++ L IR+++ D G YTCVA+N G E+ L V
Sbjct: 256 WRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKI 175
P F+ K ++ A +V F C A +P A W G + + + R +
Sbjct: 315 PHFVVKPRDQVVALGRTVTF-QCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSV 371
Query: 176 DG-GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG--PPGPPGGVQILGIQRSSV 232
G+LTI NV SDVG Y C + G I + L + PP ++ G +V
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTV 430
Query: 233 TLEWT---DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY-----NGRKRAT 284
++ T + G P+ + ST + + N + RY GR
Sbjct: 431 AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 490
Query: 285 VSTTL--LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
ST W+ Y +Q + P QP P T + AP+ +T
Sbjct: 491 ASTPSGEATWSAY-IEVQEFGV--PVQPPRP-----TDPNLIPSAPSKPEVTDVSRNTVT 542
Query: 343 ITWTP------LPTSLQNGPGIHYK-IFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTY 395
++W P PTS H W+ V+ ++ +K Y+ + +
Sbjct: 543 LSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAAN 602
Query: 396 FYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSA--RSFNSTALN-----VT 448
Y D +D P +V+ D QV +L +A N T L+ V
Sbjct: 603 AYGISD--PSQISD--PVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSPSSIEVH 658
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W +DQ + ++G I +R + + ++ + +N +I L+ Y +K
Sbjct: 659 WT-VDQQSQYIQGYKILYR-PSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKAR 716
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
F + +G +SE +T +AP PP V V +D ++ + P + + + +
Sbjct: 717 PFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQE 776
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
++W L + + V I ++PG Y++ V A + G G S P
Sbjct: 777 YKVWCLGNETRYHINKTVD-GSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830
Score = 94.3 bits (224), Expect = 1e-18
Identities = 64/222 (28%), Positives = 100/222 (45%), Gaps = 14/222 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
+Y C A+N L + S +A L V L+ F+++P ++ + G ++C+P P+PT
Sbjct: 105 VYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMV--AVGEPAVMECQPPRGHPEPT 162
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESR-GRLIVLRA 117
+WKKD + +R G L+I + D G Y CV N G ES L VL
Sbjct: 163 ISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER 222
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+ K P + V+ C A DP+ W KD +L ++ D
Sbjct: 223 PSFV-KRPSNLAVTVDDSAEFKCEARGDPV--PTVRWR------KDDGELPKSRYEIRDD 273
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I V+ D+G Y CV ++ +G+ + L ++ PP
Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 68.9 bits (161), Expect = 5e-11
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 19/205 (9%)
Query: 15 SSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG--- 71
S ++LR P +HP +L S+G TL CK E P PT W K +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIV--SKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDD 75
Query: 72 --GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEK 123
R + +G+L ++ SR DEGVY CVA+N G S + + R +
Sbjct: 76 PRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQ 135
Query: 124 LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIY 183
P + V + C + W +G + D ++RI I GG+L I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGH-PEPTISWKKDGSPLDDK-----DERITIRGGKLMIT 189
Query: 184 NVSLSDVGDYECVVKSAIGRISSHV 208
SD G Y CV + +G S V
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEV 214
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 118 bits (283), Expect = 9e-26
Identities = 144/588 (24%), Positives = 243/588 (41%), Gaps = 78/588 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + + +SA L V P F P + + G VT +C+ P+P W
Sbjct: 328 YTCVAENMVGKAEASATLTVQE-PPHFVVKPRDQVV--ALGRTVTFQCEATGNPQPAIFW 384
Query: 62 KKD---NIVIG----AGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
+++ N++ RF +++ G+L I + R D G Y C N G+ ++ L
Sbjct: 385 RREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLE 444
Query: 114 VL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
V R P + + P T V+ L C A P+ LW +G+ +
Sbjct: 445 VTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGVLVSTQ---- 498
Query: 169 VNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQLRIEG----PPGP--- 218
+ RIK ++ G L I L D G Y C+ + G S++++++ G PP P
Sbjct: 499 -DSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDP 557
Query: 219 ------PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWN-STWYVISENIPNV 271
P ++ + R++VTL W + ++G T Y++ +H + S+W ++EN+
Sbjct: 558 NLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKT- 616
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANV 331
E G K P AIY F ++A N G PS S T P +
Sbjct: 617 -ETSAIKGLK---------PNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDH 666
Query: 332 SGGGGKTGDLTITWTPLPTSLQNGP-GIH------------YKIFWRRNGSEVEFQSLLL 378
+ G+ + PT L + +H YKI +R +G+ L+
Sbjct: 667 KQVQRELGN-AVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLV 725
Query: 379 KKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ--LVS 436
+ V I Y++K + F + G +SE+ + E+ P PQ VS
Sbjct: 726 FEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVS 785
Query: 437 ARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTT--RNWALI 494
N TA+ V+W P + + G + K W N E Y++++T ++++
Sbjct: 786 KNDGNGTAILVSWQPPPEDTQ--NGMV--QEYKVWCLGN---ETRYHINKTVDGSTFSVV 838
Query: 495 VG-LQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNV 540
+ L P Y V+V A AG G +SE ++++ P P V++
Sbjct: 839 IPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSL 886
Score = 112 bits (270), Expect = 3e-24
Identities = 149/648 (22%), Positives = 252/648 (38%), Gaps = 45/648 (6%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C N + S A+L VL +PSF K P L + KC+ P PT
Sbjct: 238 YVCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTVDDSAE--FKCEARGDPVPTVR 294
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W+KD+ + + I ++ L IR+++ D G YTCVA+N G E+ L V P F
Sbjct: 295 WRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHF 353
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKI-DG 177
+ K ++ A +V F C A +P A W G + + + R +
Sbjct: 354 VVKPRDQVVALGRTVTF-QCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQT 410
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLE 235
G+LTI NV SDVG Y C + G I + L + PP ++ G +V ++
Sbjct: 411 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVD 469
Query: 236 WT---DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY-----NGRKRATVST 287
T + G P+ + ST + + N + RY GR ST
Sbjct: 470 GTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIAST 529
Query: 288 TL--LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW 345
W+ Y +Q + P QP P T + AP+ +T++W
Sbjct: 530 PSGEATWSAY-IEVQEFGV--PVQPPRP-----TDPNLIPSAPSKPEVTDVSRNTVTLSW 581
Query: 346 TP------LPTSLQNGPGIHYK-IFWRRNGSEVEFQSLLLK--KYGNIGTYVVHISSTYF 396
P PTS H W+ V+ ++ +K K I ++V ++ Y
Sbjct: 582 QPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 641
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAE-DMPQVAPQLVSARSFNSTALNVTWNPIDQS 455
+ P S+ V + ++ L + +S+++ V W +DQ
Sbjct: 642 ISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT-VDQQ 700
Query: 456 RERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ ++G I +R + + ++ + +N +I L+ Y +K F + +
Sbjct: 701 SQYIQGYKILYR-PSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQ 759
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G +SE +T +AP PP V V +D ++ + P + + + + ++W L
Sbjct: 760 GADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLG 819
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+ + V I ++PG Y++ V A + G G S P
Sbjct: 820 NETRYHINKTVD-GSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 866
Score = 96.7 bits (230), Expect = 2e-19
Identities = 64/219 (29%), Positives = 100/219 (45%), Gaps = 14/219 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
+Y C A+N L + S +A L V L+ F+++P ++ + G ++C+P P+PT
Sbjct: 144 VYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMV--AVGEPAVMECQPPRGHPEPT 201
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESR-GRLIVLRA 117
+WKKD + +R G L+I + D G Y CV N G ES L VL
Sbjct: 202 ISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER 261
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+ K P + V+ C A DP+ W KD +L ++ D
Sbjct: 262 PSFV-KRPSNLAVTVDDSAEFKCEARGDPV--PTVRWR------KDDGELPKSRYEIRDD 312
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I V+ D+G Y CV ++ +G+ + L ++ PP
Sbjct: 313 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPP 351
Score = 70.5 bits (165), Expect = 2e-11
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 19/206 (9%)
Query: 14 YSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG-- 71
Y+ ++LR P +HP +L S+G TL CK E P PT W K +
Sbjct: 56 YTGSRLRQEDFPPRIVEHPSDLIV--SKGEPATLNCKAEGRPTPTIEWYKGGERVETDKD 113
Query: 72 ---GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLE 122
R + +G+L ++ SR DEGVY CVA+N G S + + R
Sbjct: 114 DPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR 173
Query: 123 KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTI 182
+ P + V + C + W +G + D ++RI I GG+L I
Sbjct: 174 QNPSDVMVAVGEPAVMECQPPRGH-PEPTISWKKDGSPLDDK-----DERITIRGGKLMI 227
Query: 183 YNVSLSDVGDYECVVKSAIGRISSHV 208
SD G Y CV + +G S V
Sbjct: 228 TYTRKSDAGKYVCVGTNMVGERESEV 253
>AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine
phosphatase, receptor type, F isoform 2 precursor
variant protein.
Length = 1552
Score = 118 bits (283), Expect = 9e-26
Identities = 118/463 (25%), Positives = 190/463 (41%), Gaps = 34/463 (7%)
Query: 174 KIDGGELTIYNVS-LSDVGDY--ECVVKSAIGR--ISSHVQLRI--EGPPGPPGGVQILG 226
++DG T Y++ LS +Y + ++IGR S V+ R + P PP VQ
Sbjct: 21 EVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARM 80
Query: 227 IQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVS 286
+ S++ ++W + GY R ++ S PN + TV
Sbjct: 81 LSASTMLVQWEPPEEPNGLVRGY----RVYYTPD----SRRPPNAWHKHNTDAGLLTTVG 132
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
+ LLP Y R+ A +G G PS P+ Q T P + PA+ + ++W
Sbjct: 133 S-LLPGITYSLRVLAFTAVGDGPPS-PTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWL 189
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P Q ++ ++W + + + + +Y + T Y ++ A
Sbjct: 190 LPP---QERIIMYELVYWAAEDEDQQHKVT----FDPTSSYTLEDLKPD--TLYRFQLAA 240
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+D+G G + + +A+ P PQ V S ST + V+W P + G + +
Sbjct: 241 RSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPADSRNGVITQY 298
Query: 467 RLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLE 524
+ Y E++ + +SR +W L VGL+ T Y V V A G GPES L
Sbjct: 299 SVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGPGPESSPVLV 357
Query: 525 RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDT 584
RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 358 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 417
Query: 585 I--VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
I V + E IS + P +Y++ V AY+ GDG S P I
Sbjct: 418 IQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 460
Score = 94.7 bits (225), Expect = 1e-18
Identities = 83/333 (24%), Positives = 144/333 (43%), Gaps = 17/333 (5%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P +Y F++ A + +G G P+ + T+ P P V + + ++W P
Sbjct: 228 LKPDTLYRFQLAARSDMGVGV-FTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP 286
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P +NG Y + + E + ++ ++ + +T Y V V+A
Sbjct: 287 PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSW--DLVGLEKWTEYRVWVRAHT 344
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
D+GPGPES V + + ED+P P+ V NSTA++V W S++ G++ G+++
Sbjct: 345 DVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ--HGQIRGYQV 402
Query: 469 KYWKQENKEEE---CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLER 525
Y + EN E I + I GL P+T Y V V A+ + G+G S+ +
Sbjct: 403 TYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVT 462
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
T P +P ++ A + L+ W P LLGY+++ D+ D
Sbjct: 463 T--TVPGRPTMMISTTAMNTALLQ--WH--PPKELPGELLGYRLQYCRADEARPNTIDFG 516
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+H ++ + G +Y R+ A + G G
Sbjct: 517 KDDQH---FTVTGLHKGTTYIFRLAAKNRAGLG 546
Score = 79.8 bits (188), Expect = 3e-14
Identities = 67/271 (24%), Positives = 118/271 (43%), Gaps = 20/271 (7%)
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
P +Y I +R G+E FQ + + T I ++ Y +V A N IG GP
Sbjct: 2 PVTYYGIQYRAAGTEGPFQEV-----DGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPP 56
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
SE V + E P P+ V AR +++ + V W P ++ +RG + Y+ ++
Sbjct: 57 SEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRV-----YYTPDS 111
Query: 476 KEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ ++ T VG L P Y ++V+AF + G+GP S +T + P +
Sbjct: 112 RRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ- 170
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
PA T +++ W + P +E ++ Y++ W + + T P
Sbjct: 171 PADFQAEVESDTRIQLSW-LLPP---QERIIMYELVYWAAEDEDQQHKVTFDPTS---SY 223
Query: 595 YISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
+ ++ P Y ++ A S+ G G + +PTI
Sbjct: 224 TLEDLKPDTLYRFQLAARSDMGVG-VFTPTI 253
Score = 60.1 bits (139), Expect = 3e-08
Identities = 85/331 (25%), Positives = 139/331 (41%), Gaps = 33/331 (9%)
Query: 202 GRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLEW---TDSNSNGRPITGYMLTGRTH 256
G SS V +R + P GPP V++ + ++V + W S +G+ I GY +T
Sbjct: 349 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ-IRGYQVTYVRL 407
Query: 257 WNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQ 316
N +P + +V + T + L P Y + A G G S P
Sbjct: 408 ENGE----PRGLPIIQDV--MLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV 461
Query: 317 FSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSL 376
+T +P +S T + W P P L G + Y++ + R E ++
Sbjct: 462 TTTVPGRP---TMMISTTAMNTA--LLQWHP-PKELP-GELLGYRLQYCR-ADEARPNTI 513
Query: 377 LLKKYGNIGTYV-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLV 435
K T +H +TY + ++ A N G G E E I + ED+P PQ +
Sbjct: 514 DFGKDDQHFTVTGLHKGTTYIF-----RLAAKNRAGLGEEFE-KEIRTPEDLPSGFPQNL 567
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
++ + W+P ER G++I + + + + N ++E + ++ TR +
Sbjct: 568 HVTGLTTSTTELAWDP-PVLAER-NGRIISYTVVF-RDINSQQE-LQNITTDTR--FTLT 621
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
GL+PDT Y +KV A+ S G GP S RT
Sbjct: 622 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRT 652
Score = 43.2 bits (97), Expect = 0.003
Identities = 60/249 (24%), Positives = 100/249 (40%), Gaps = 28/249 (11%)
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
Y FR+ A N G G+ + T D P P N+ G T + W P + +N
Sbjct: 533 YIFRLAAKNRAGLGEEF--EKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 590
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
G I Y + +R S+ E Q++ ++ T YD+KV+A+ G GP
Sbjct: 591 GRIISYTVVFRDINSQQELQNITTDTR-------FTLTGLKPDTTYDIKVRAWTSKGSGP 643
Query: 415 ESEVVTIYSAEDMP--QVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWK 472
S + + MP QV + + T++ ++W D + + K++ +
Sbjct: 644 LSPSI---QSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKIL------YN 694
Query: 473 QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
++ E + + R LI LQP+T Y +M S+ G + + P
Sbjct: 695 GQSVEVD-----GHSMRK--LIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPDLLPH 747
Query: 533 KP-PASVNV 540
KP PAS +
Sbjct: 748 KPLPASAYI 756
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 117 bits (282), Expect = 1e-25
Identities = 145/590 (24%), Positives = 244/590 (41%), Gaps = 79/590 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A+N + + +SA L V S P F P + + G VT +C+ P+P
Sbjct: 289 YTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVV--ALGRTVTFQCEATGNPQPAI 346
Query: 60 TWKKD---NIVIG----AGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGR 111
W+++ N++ RF +++ G+L I + R D G Y C N G+ ++
Sbjct: 347 FWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAY 406
Query: 112 LIVL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
L V R P + + P T V+ L C A P+ LW +G+ +
Sbjct: 407 LEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGVLVSTQ-- 462
Query: 167 LYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQLRIEG----PPGP- 218
+ RIK ++ G L I L D G Y C+ + G S++++++ G PP P
Sbjct: 463 ---DSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPT 519
Query: 219 --------PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWN-STWYVISENIP 269
P ++ + R++VTL W + ++G T Y++ +H + S+W ++EN+
Sbjct: 520 DPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVK 579
Query: 270 NVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA 329
E G K P AIY F ++A N G PS S T P
Sbjct: 580 T--ETSAIKGLK---------PNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGV 628
Query: 330 NVSGGGGKTGDLTITWTPLPTSLQNGP-GIH------------YKIFWRRNGSEVEFQSL 376
+ + G+ + PT L + +H YKI +R +G+
Sbjct: 629 DHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDW 687
Query: 377 LLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ--L 434
L+ + V I Y++K + F + G +SE+ + E+ P PQ
Sbjct: 688 LVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVT 747
Query: 435 VSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTT--RNWA 492
VS N TA+ V+W P + + G + K W N E Y++++T ++
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQ--NGMV--QEYKVWCLGN---ETRYHINKTVDGSTFS 800
Query: 493 LIVG-LQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAPQKPPASVNV 540
+++ L P Y V+V A AG G +SE ++++ P P V++
Sbjct: 801 VVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSL 850
Score = 106 bits (255), Expect = 2e-22
Identities = 149/651 (22%), Positives = 252/651 (38%), Gaps = 48/651 (7%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C N + S A+L VL +PSF K P L + KC+ P PT
Sbjct: 199 YVCVGTNMVGERESEVAELTVLE-RPSFVKRPSNLAVTVDDSAE--FKCEARGDPVPTVR 255
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL---RA 117
W+KD+ + + I ++ L IR+++ D G YTCVA+N G E+ L V
Sbjct: 256 WRKDDGELPKS-RYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEP 314
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKI 175
P F+ K ++ A +V F C A +P A W G + + + R +
Sbjct: 315 PHFVVKPRDQVVALGRTVTF-QCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSV 371
Query: 176 DG-GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG--PPGPPGGVQILGIQRSSV 232
G+LTI NV SDVG Y C + G I + L + PP ++ G +V
Sbjct: 372 SQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTV 430
Query: 233 TLEWT---DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY-----NGRKRAT 284
++ T + G P+ + ST + + N + RY GR
Sbjct: 431 AVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 490
Query: 285 VSTTL--LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
ST W+ Y +Q + P QP P T + AP+ +T
Sbjct: 491 ASTPSGEATWSAY-IEVQEFGV--PVQPPRP-----TDPNLIPSAPSKPEVTDVSRNTVT 542
Query: 343 ITWTP------LPTSLQNGPGIHYK-IFWRRNGSEVEFQSLLLK--KYGNIGTYVVHISS 393
++W P PTS H W+ V+ ++ +K K I ++V ++
Sbjct: 543 LSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAAN 602
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAE-DMPQVAPQLVSARSFNSTALNVTWNPI 452
Y + P S+ V + ++ L + +S+++ V W +
Sbjct: 603 AYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT-V 661
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
DQ + ++G I +R + + ++ + +N +I L+ Y +K F +
Sbjct: 662 DQQSQYIQGYKILYR-PSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFN 720
Query: 513 AGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLW 572
+G +SE +T +AP PP V V +D ++ + P + + + + ++W
Sbjct: 721 EFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVW 780
Query: 573 ELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
L + + V I ++PG Y++ V A + G G S P
Sbjct: 781 CLGNETRYHINKTVD-GSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 830
Score = 94.3 bits (224), Expect = 1e-18
Identities = 64/222 (28%), Positives = 100/222 (45%), Gaps = 14/222 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPT 58
+Y C A+N L + S +A L V L+ F+++P ++ + G ++C+P P+PT
Sbjct: 105 VYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMV--AVGEPAVMECQPPRGHPEPT 162
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESR-GRLIVLRA 117
+WKKD + +R G L+I + D G Y CV N G ES L VL
Sbjct: 163 ISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLER 222
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+ K P + V+ C A DP+ W KD +L ++ D
Sbjct: 223 PSFV-KRPSNLAVTVDDSAEFKCEARGDPV--PTVRWR------KDDGELPKSRYEIRDD 273
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I V+ D+G Y CV ++ +G+ + L ++ PP
Sbjct: 274 HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 68.9 bits (161), Expect = 5e-11
Identities = 58/205 (28%), Positives = 83/205 (40%), Gaps = 19/205 (9%)
Query: 15 SSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG--- 71
S ++LR P +HP +L S+G TL CK E P PT W K +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIV--SKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDD 75
Query: 72 --GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEK 123
R + +G+L ++ SR DEGVY CVA+N G S + + R +
Sbjct: 76 PRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQ 135
Query: 124 LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIY 183
P + V + C + W +G + D ++RI I GG+L I
Sbjct: 136 NPSDVMVAVGEPAVMECQPPRGH-PEPTISWKKDGSPLDDK-----DERITIRGGKLMIT 189
Query: 184 NVSLSDVGDYECVVKSAIGRISSHV 208
SD G Y CV + +G S V
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEV 214
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 117 bits (281), Expect = 2e-25
Identities = 139/565 (24%), Positives = 231/565 (40%), Gaps = 74/565 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N++ +SA L V + P F P + ++G VT C+ + P+P W
Sbjct: 291 YMCIAENRVGKMEASATLTVRA-PPQFVVRPRDQIV--AQGRTVTFPCETKGNPQPAVFW 347
Query: 62 KKD---NIVIG-----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
+K+ N++ + ++ G+L I + R D G Y C A G+ ++ +L
Sbjct: 348 QKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLE 407
Query: 114 VL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
V R P + + P T V+ L C A DP+ W G
Sbjct: 408 VTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR---- 461
Query: 169 VNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP------------ 215
+ R I + G L I N+ +SD G Y CV S+ G S L +
Sbjct: 462 -DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSD 520
Query: 216 -PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTH-WNSTWYVISENIPNVME 273
PGPP Q+ + ++SVTL W P + Y++ + +++W ++ ++ +
Sbjct: 521 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLY 580
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
R L P IY F ++AIN G PS S T P +
Sbjct: 581 TVR-----------GLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQ 629
Query: 334 GGGKTGDLTI-TWTPL---PTSLQ------NGPGI--HYKIFWRRNG---SEVEFQSLLL 378
+ GD+ + P+ PT++Q P Y++ +R+ + +Q+L
Sbjct: 630 VQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDA 689
Query: 379 KKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ---LV 435
K +V++ Y++KV+ + + G +SE T+ + E+ P PQ ++
Sbjct: 690 KVPTERSAVLVNLKKG---VTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVL 746
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
+ S+NST+++V+W+P + G I K W N+ I +I
Sbjct: 747 TVGSYNSTSISVSWDPPPPDHQ--NG--IIQEYKIWCLGNETRFHINKTVDAAIRSVIIG 802
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESE 520
GL P Y V+V A SAG G +SE
Sbjct: 803 GLFPGIQYRVEVAASTSAGVGVKSE 827
Score = 93.5 bits (222), Expect = 2e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 14/218 (6%)
Query: 2 YQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y C A+N L + S +A L V L+ F+++P ++ + G L+C+P P+PT
Sbjct: 108 YVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV--AAGEPAILECQPPRGHPEPTI 165
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYG-TDESRGRLIVLRAP 118
WKKD + I +R G L+I + D G+YTCV N G D L V P
Sbjct: 166 YWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERP 225
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
FL + ++ + +V F C DP W KD +DL + D
Sbjct: 226 TFLRRPINQVVLEEEAVEF-RCQVQGDP--QPTVRWK------KDDADLPRGRYDIKDDY 276
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +D G Y C+ ++ +G++ + L + PP
Sbjct: 277 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP 314
Score = 89.4 bits (212), Expect = 4e-17
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 11/216 (5%)
Query: 1 MYQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
MY C N + S A+L V +P+F + P+ E V +C+ + P+PT
Sbjct: 200 MYTCVGTNMVGERDSDPAELTVFE-RPTFLRRPINQVVLEEEA--VEFRCQVQGDPQPTV 256
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
WKKD+ + G + I ++ L I++ DEG Y C+A+N+ G E+ L V P+
Sbjct: 257 RWKKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 315
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKID- 176
F+ + +I AQ +V F C +P A W G + + + N R +
Sbjct: 316 FVVRPRDQIVAQGRTVTF-PCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 372
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G+LTI N+ SD G Y C + G I + QL +
Sbjct: 373 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 408
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 83/201 (41%), Gaps = 19/201 (9%)
Query: 17 AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG----- 71
++LR P +HP ++ S+G TL CK E P PT W KD +
Sbjct: 22 SRLRQEDFPPRIVEHPSDVIV--SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR 79
Query: 72 GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEKLP 125
R + +G+L ++ S+ DEG Y CVA+N G SR + + R + P
Sbjct: 80 SHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNP 139
Query: 126 PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNV 185
+ L C T Y W + +RI D + RI I GG+L I N
Sbjct: 140 TDVVVAAGEPAILECQPPRGHPEPTIY-WKKDKVRIDDKEE-----RISIRGGKLMISNT 193
Query: 186 SLSDVGDYECVVKSAIGRISS 206
SD G Y CV + +G S
Sbjct: 194 RKSDAGMYTCVGTNMVGERDS 214
Score = 58.4 bits (135), Expect = 8e-08
Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
DI P P V +++ V +L + T + VTW +D+ + ++G + +R
Sbjct: 617 DISP-PAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQ 674
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
Q + + T R+ A++V L+ Y +KV + + +G +SE RT
Sbjct: 675 TSGLQATSSWQNLDAKVPTERS-AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 733
Query: 529 KAPQKPPASV---NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
+AP PP SV V +++ T++ V W P ++ + YK+ W L + +
Sbjct: 734 EAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINKT 791
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
V + I + PG Y + V A ++ G G S P
Sbjct: 792 VDAAIR-SVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 828
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 117 bits (281), Expect = 2e-25
Identities = 139/565 (24%), Positives = 231/565 (40%), Gaps = 74/565 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N++ +SA L V + P F P + ++G VT C+ + P+P W
Sbjct: 307 YMCIAENRVGKMEASATLTVRA-PPQFVVRPRDQIV--AQGRTVTFPCETKGNPQPAVFW 363
Query: 62 KKD---NIVIG-----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
+K+ N++ + ++ G+L I + R D G Y C A G+ ++ +L
Sbjct: 364 QKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLE 423
Query: 114 VL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
V R P + + P T V+ L C A DP+ W G
Sbjct: 424 VTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR---- 477
Query: 169 VNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP------------ 215
+ R I + G L I N+ +SD G Y CV S+ G S L +
Sbjct: 478 -DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSD 536
Query: 216 -PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTH-WNSTWYVISENIPNVME 273
PGPP Q+ + ++SVTL W P + Y++ + +++W ++ ++ +
Sbjct: 537 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLY 596
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
R L P IY F ++AIN G PS S T P +
Sbjct: 597 TVR-----------GLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQ 645
Query: 334 GGGKTGDLTI-TWTPL---PTSLQ------NGPGI--HYKIFWRRNG---SEVEFQSLLL 378
+ GD+ + P+ PT++Q P Y++ +R+ + +Q+L
Sbjct: 646 VQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDA 705
Query: 379 KKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ---LV 435
K +V++ Y++KV+ + + G +SE T+ + E+ P PQ ++
Sbjct: 706 KVPTERSAVLVNLKKG---VTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVL 762
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
+ S+NST+++V+W+P + G I K W N+ I +I
Sbjct: 763 TVGSYNSTSISVSWDPPPPDHQ--NG--IIQEYKIWCLGNETRFHINKTVDAAIRSVIIG 818
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESE 520
GL P Y V+V A SAG G +SE
Sbjct: 819 GLFPGIQYRVEVAASTSAGVGVKSE 843
Score = 93.5 bits (222), Expect = 2e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 14/218 (6%)
Query: 2 YQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y C A+N L + S +A L V L+ F+++P ++ + G L+C+P P+PT
Sbjct: 124 YVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV--AAGEPAILECQPPRGHPEPTI 181
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYG-TDESRGRLIVLRAP 118
WKKD + I +R G L+I + D G+YTCV N G D L V P
Sbjct: 182 YWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERP 241
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
FL + ++ + +V F C DP W KD +DL + D
Sbjct: 242 TFLRRPINQVVLEEEAVEF-RCQVQGDP--QPTVRWK------KDDADLPRGRYDIKDDY 292
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +D G Y C+ ++ +G++ + L + PP
Sbjct: 293 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP 330
Score = 89.4 bits (212), Expect = 4e-17
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 11/216 (5%)
Query: 1 MYQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
MY C N + S A+L V +P+F + P+ E V +C+ + P+PT
Sbjct: 216 MYTCVGTNMVGERDSDPAELTVFE-RPTFLRRPINQVVLEEEA--VEFRCQVQGDPQPTV 272
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
WKKD+ + G + I ++ L I++ DEG Y C+A+N+ G E+ L V P+
Sbjct: 273 RWKKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 331
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKID- 176
F+ + +I AQ +V F C +P A W G + + + N R +
Sbjct: 332 FVVRPRDQIVAQGRTVTF-PCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 388
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G+LTI N+ SD G Y C + G I + QL +
Sbjct: 389 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 424
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 83/201 (41%), Gaps = 19/201 (9%)
Query: 17 AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG----- 71
++LR P +HP ++ S+G TL CK E P PT W KD +
Sbjct: 38 SRLRQEDFPPRIVEHPSDVIV--SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR 95
Query: 72 GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEKLP 125
R + +G+L ++ S+ DEG Y CVA+N G SR + + R + P
Sbjct: 96 SHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNP 155
Query: 126 PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNV 185
+ L C T Y W + +RI D + RI I GG+L I N
Sbjct: 156 TDVVVAAGEPAILECQPPRGHPEPTIY-WKKDKVRIDDKEE-----RISIRGGKLMISNT 209
Query: 186 SLSDVGDYECVVKSAIGRISS 206
SD G Y CV + +G S
Sbjct: 210 RKSDAGMYTCVGTNMVGERDS 230
Score = 58.4 bits (135), Expect = 8e-08
Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
DI P P V +++ V +L + T + VTW +D+ + ++G + +R
Sbjct: 633 DISP-PAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQ 690
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
Q + + T R+ A++V L+ Y +KV + + +G +SE RT
Sbjct: 691 TSGLQATSSWQNLDAKVPTERS-AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 749
Query: 529 KAPQKPPASV---NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
+AP PP SV V +++ T++ V W P ++ + YK+ W L + +
Sbjct: 750 EAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINKT 807
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
V + I + PG Y + V A ++ G G S P
Sbjct: 808 VDAAIR-SVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 844
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 117 bits (281), Expect = 2e-25
Identities = 139/565 (24%), Positives = 231/565 (40%), Gaps = 74/565 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N++ +SA L V + P F P + ++G VT C+ + P+P W
Sbjct: 293 YMCIAENRVGKMEASATLTVRA-PPQFVVRPRDQIV--AQGRTVTFPCETKGNPQPAVFW 349
Query: 62 KKD---NIVIG-----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
+K+ N++ + ++ G+L I + R D G Y C A G+ ++ +L
Sbjct: 350 QKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLE 409
Query: 114 VL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
V R P + + P T V+ L C A DP+ W G
Sbjct: 410 VTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR---- 463
Query: 169 VNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP------------ 215
+ R I + G L I N+ +SD G Y CV S+ G S L +
Sbjct: 464 -DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSD 522
Query: 216 -PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTH-WNSTWYVISENIPNVME 273
PGPP Q+ + ++SVTL W P + Y++ + +++W ++ ++ +
Sbjct: 523 LPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLY 582
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
R L P IY F ++AIN G PS S T P +
Sbjct: 583 TVR-----------GLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQ 631
Query: 334 GGGKTGDLTI-TWTPL---PTSLQ------NGPGI--HYKIFWRRNG---SEVEFQSLLL 378
+ GD+ + P+ PT++Q P Y++ +R+ + +Q+L
Sbjct: 632 VQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDA 691
Query: 379 KKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ---LV 435
K +V++ Y++KV+ + + G +SE T+ + E+ P PQ ++
Sbjct: 692 KVPTERSAVLVNLKKG---VTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVL 748
Query: 436 SARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
+ S+NST+++V+W+P + G I K W N+ I +I
Sbjct: 749 TVGSYNSTSISVSWDPPPPDHQ--NG--IIQEYKIWCLGNETRFHINKTVDAAIRSVIIG 804
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESE 520
GL P Y V+V A SAG G +SE
Sbjct: 805 GLFPGIQYRVEVAASTSAGVGVKSE 829
Score = 93.5 bits (222), Expect = 2e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 14/218 (6%)
Query: 2 YQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y C A+N L + S +A L V L+ F+++P ++ + G L+C+P P+PT
Sbjct: 110 YVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV--AAGEPAILECQPPRGHPEPTI 167
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYG-TDESRGRLIVLRAP 118
WKKD + I +R G L+I + D G+YTCV N G D L V P
Sbjct: 168 YWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERP 227
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
FL + ++ + +V F C DP W KD +DL + D
Sbjct: 228 TFLRRPINQVVLEEEAVEF-RCQVQGDP--QPTVRWK------KDDADLPRGRYDIKDDY 278
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +D G Y C+ ++ +G++ + L + PP
Sbjct: 279 TLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP 316
Score = 89.4 bits (212), Expect = 4e-17
Identities = 64/216 (29%), Positives = 100/216 (46%), Gaps = 11/216 (5%)
Query: 1 MYQCEAKNQLKASYSS-AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
MY C N + S A+L V +P+F + P+ E V +C+ + P+PT
Sbjct: 202 MYTCVGTNMVGERDSDPAELTVFE-RPTFLRRPINQVVLEEEA--VEFRCQVQGDPQPTV 258
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
WKKD+ + G + I ++ L I++ DEG Y C+A+N+ G E+ L V P+
Sbjct: 259 RWKKDDADLPRG-RYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQ 317
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR--IKDSSDLYVNKRIKID- 176
F+ + +I AQ +V F C +P A W G + + + N R +
Sbjct: 318 FVVRPRDQIVAQGRTVTF-PCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSP 374
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G+LTI N+ SD G Y C + G I + QL +
Sbjct: 375 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEV 410
Score = 74.1 bits (174), Expect = 1e-12
Identities = 59/201 (29%), Positives = 83/201 (41%), Gaps = 19/201 (9%)
Query: 17 AQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG----- 71
++LR P +HP ++ S+G TL CK E P PT W KD +
Sbjct: 24 SRLRQEDFPPRIVEHPSDVIV--SKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPR 81
Query: 72 GKRFITENGNLIIRQL-----SRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEKLP 125
R + +G+L ++ S+ DEG Y CVA+N G SR + + R + P
Sbjct: 82 SHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNP 141
Query: 126 PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNV 185
+ L C T Y W + +RI D + RI I GG+L I N
Sbjct: 142 TDVVVAAGEPAILECQPPRGHPEPTIY-WKKDKVRIDDKEE-----RISIRGGKLMISNT 195
Query: 186 SLSDVGDYECVVKSAIGRISS 206
SD G Y CV + +G S
Sbjct: 196 RKSDAGMYTCVGTNMVGERDS 216
Score = 58.4 bits (135), Expect = 8e-08
Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
DI P P V +++ V +L + T + VTW +D+ + ++G + +R
Sbjct: 619 DISP-PAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQ 676
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
Q + + T R+ A++V L+ Y +KV + + +G +SE RT
Sbjct: 677 TSGLQATSSWQNLDAKVPTERS-AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 735
Query: 529 KAPQKPPASV---NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
+AP PP SV V +++ T++ V W P ++ + YK+ W L + +
Sbjct: 736 EAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINKT 793
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
V + I + PG Y + V A ++ G G S P
Sbjct: 794 VDAAIR-SVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 830
>AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein
protein.
Length = 1185
Score = 116 bits (280), Expect = 2e-25
Identities = 81/284 (28%), Positives = 136/284 (47%), Gaps = 11/284 (3%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P+ Y FR++ +NI+G PS PS + T P APANVS L + W PL
Sbjct: 30 LNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPL 89
Query: 349 PTSLQNG--PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P NG + YKI + R+ + S +++ + + +T Y V+VQA
Sbjct: 90 PEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEE---WTEYRVQVQA 146
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
FN IG GP S+ V + E +P P VSA + S+++ W+ + ++ G ++G+
Sbjct: 147 FNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLGRWSEVPEADR--NGLVLGY 204
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLER 525
++ Y ++++ + + + + A + GL Y V+V+AF G+G P LER
Sbjct: 205 KVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILER 264
Query: 526 TFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
T P PP + T++R++W+ P +L Y++
Sbjct: 265 TLDDVP-GPPMGILFPEVRTTSVRLIWQ--PPAAPNGIILAYQI 305
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/230 (26%), Positives = 107/230 (46%), Gaps = 2/230 (0%)
Query: 397 YTPYDVKVQAFNDIGPGPESEVVT-IYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQS 455
+T Y +++ N +G P S+ I + + P +AP VS R+ + T+L + W P+ +
Sbjct: 33 FTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEM 92
Query: 456 RERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ +G+++KY + + + + + I L+ T Y V+V AFN+ G
Sbjct: 93 EYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGS 152
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
GP S+ + RT P P +V+ A +++ W V + +LGYKV E D
Sbjct: 153 GPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLGRWSEVPEADRNGLVLGYKVMYKEKD 212
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
D + +V A ++ + Y ++VLA++ GDG S P I
Sbjct: 213 SD-TQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPI 261
Score = 88.2 bits (209), Expect = 8e-17
Identities = 89/336 (26%), Positives = 137/336 (40%), Gaps = 21/336 (6%)
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
YE R+ N +G G PS+P + P AP NV G L +TW P P QN
Sbjct: 564 YEIRMSVYNAVGEG-PSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQN 622
Query: 355 GPGIHYKI-FWR-RNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGP 412
G YKI FW + G+ E L + V + + YT Y V V AFN G
Sbjct: 623 GDIQGYKIYFWEAQRGNLTERVKTLF-----LAENSVKLKNLTGYTAYMVSVAAFNAAGD 677
Query: 413 GPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY-- 470
GP S + + P AP V +T++NV+W ++ + G L G+RL Y
Sbjct: 678 GPRSTPTQGQTQQAAPS-APSSVKFSELTTTSVNVSW----EAPQFPNGILEGYRLVYEP 732
Query: 471 -WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
+ + + + W + L Y ++ A + GPE E + +
Sbjct: 733 CSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGE 791
Query: 530 APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIE 589
PP V + + + + W P + P+ Y + D+ + +P E
Sbjct: 792 GAPGPP-GVPIIVRYSSAIAIHWSSGDP--GKGPITRYVIEARPSDEGLWDILIKDIPKE 848
Query: 590 HKLEAYISNII-PGKSYNLRVLAYSNGGDGRMSSPT 624
+ +I+ PG SY+ RV+A ++ G G SSP+
Sbjct: 849 VSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 884
Score = 83.4 bits (197), Expect = 2e-15
Identities = 97/438 (22%), Positives = 176/438 (40%), Gaps = 44/438 (10%)
Query: 212 IEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
++ PGPP G+ ++ +SV L W + I Y +T R ++ N
Sbjct: 266 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHR---------LNTTTANT 316
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN- 330
V+ R +T L P ++Y FRI A G+ + + D+P + P+
Sbjct: 317 ATVEVLAPSARQYTATGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRDRP-QPPSRP 375
Query: 331 -VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
V + + ++W P L P +Y I R S + N +++V
Sbjct: 376 MVQQEDVRARSVLLSWEPGSDGL--SPVRYYTIQTRELPSG-RWALHSASVSHNASSFIV 432
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+T Y +V+A NDIG S E ++ + + P AP ++S +T++ +
Sbjct: 433 DRLKP--FTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIR 490
Query: 449 WNPIDQSRERLRGKLIGHRLKYWK--QENKEEECIYYLSRTTRNWALIV----------- 495
W P + +++ G L+G R++Y + E + ++ WA +
Sbjct: 491 WQP--PAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRP 548
Query: 496 --------GLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTT 547
L Y +++ +N+ GEGP S P P +V V T
Sbjct: 549 SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQ 608
Query: 548 LRVVWRYVQPTNEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEAYISNIIPGKSYN 606
L V W ++ + GYK+ WE + +++ T+ E+ ++ + N+ +Y
Sbjct: 609 LDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVK--LKNLTGYTAYM 666
Query: 607 LRVLAYSNGGDGRMSSPT 624
+ V A++ GDG S+PT
Sbjct: 667 VSVAAFNAAGDGPRSTPT 684
Score = 81.8 bits (193), Expect = 7e-15
Identities = 75/332 (22%), Positives = 138/332 (41%), Gaps = 13/332 (3%)
Query: 292 WAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTS 351
W Y ++QA N +G G P + + T P P NVS + + W+ +P +
Sbjct: 137 WTEYRVQVQAFNAIGSG-PWSQTVVGRTRESVPSSGPTNVSALATTSSSMLGRWSEVPEA 195
Query: 352 LQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
+NG + YK+ ++ S+ + + L++ GN + ++ Y Y+V+V AF IG
Sbjct: 196 DRNGLVLGYKVMYKEKDSDTQPRFWLVE--GN-SSRSAQLTGLGKYVLYEVQVLAFTRIG 252
Query: 412 PG-PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY 470
G P + + +D+P P + +T++ + W P + I HRL
Sbjct: 253 DGSPSHPPILERTLDDVPG-PPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 311
Query: 471 WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKA 530
E L+ + R + GL+P++ Y ++ A G +E + T ++
Sbjct: 312 TTANTATVEV---LAPSARQYTA-TGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRD 367
Query: 531 PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEH 590
+PP+ V D V+ + ++ P+ Y ++ EL + + H
Sbjct: 368 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHS--ASVSH 425
Query: 591 KLEAYI-SNIIPGKSYNLRVLAYSNGGDGRMS 621
++I + P SY RV A ++ GD S
Sbjct: 426 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFS 457
Score = 61.7 bits (143), Expect = 8e-09
Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PGPPG V I+ S++ + W+ + PIT Y++ R W ++ ++IP
Sbjct: 791 EGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPK-- 847
Query: 273 EVDRYNGRKRATVSTTLL-PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
EV Y T S +L P Y+FR+ A+N G G PS+PS P+
Sbjct: 848 EVSSY------TFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPF 895
Score = 52.8 bits (121), Expect = 4e-06
Identities = 84/369 (22%), Positives = 141/369 (38%), Gaps = 32/369 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P P V L SS+ W++ R G +L + + S+ P V
Sbjct: 168 PSSGPTNVSALATTSSSMLGRWSEVPEADR--NGLVLGYKVMYKEK---DSDTQPRFWLV 222
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
+ R+ T L + +YE ++ A +G G PS P T D P P +
Sbjct: 223 E--GNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 279
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWR-----RNGSEVEFQSLLLKKYGNIGTYVV 389
+T + + W P + NG + Y+I R N + VE + ++Y G +
Sbjct: 280 EVRTTSVRLIWQ--PPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATG---L 334
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ-LVSARSFNSTALNVT 448
S Y + + Q G E+ VVT D PQ + +V + ++ ++
Sbjct: 335 KPESVYLFR---ITAQTRKVWGEAAEALVVTT-EKRDRPQPPSRPMVQQEDVRARSVLLS 390
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWA--LIVGLQPDTYYYVK 506
W P +R I R E + + + N + ++ L+P T Y +
Sbjct: 391 WEPGSDGLSPVRYYTIQTR------ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFR 444
Query: 507 VMAFNSAGEGPESERYLE-RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLL 565
V A N G+ SE T + AP + P ++V H T++ + W+ LL
Sbjct: 445 VKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILL 504
Query: 566 GYKVRLWEL 574
G+++R EL
Sbjct: 505 GFRIRYREL 513
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 115 bits (276), Expect = 6e-25
Identities = 139/568 (24%), Positives = 231/568 (40%), Gaps = 76/568 (13%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y C A+N++ +SA L V + P F P + ++G VT C+ + P+P
Sbjct: 8 YMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIV--AQGRTVTFPCETKGNPQPA 65
Query: 59 FTWKKD---NIVIG-----AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
W+K+ N++ + ++ G+L I + R D G Y C A G+ ++
Sbjct: 66 VFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKA 125
Query: 111 RLIVL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS 165
+L V R P + + P T V+ L C A DP+ W G
Sbjct: 126 QLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR- 182
Query: 166 DLYVNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP--------- 215
+ R I + G L I N+ +SD G Y CV S+ G S L +
Sbjct: 183 ----DPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYD 238
Query: 216 ----PGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTH-WNSTWYVISENIPN 270
PGPP Q+ + ++SVTL W P + Y++ + +++W ++ ++
Sbjct: 239 LSDLPGPPSKPQVTDVTKNSVTLSWQPGTPGTLPASAYIIEAFSQSVSNSWQTVANHVKT 298
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
+ R L P IY F ++AIN G PS S T P +
Sbjct: 299 TLYTVR-----------GLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVD 347
Query: 331 VSGGGGKTGDLTI-TWTPL---PTSLQ------NGPGI--HYKIFWRRNG---SEVEFQS 375
+ GD+ + P+ PT++Q P Y++ +R+ + +Q+
Sbjct: 348 HRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQN 407
Query: 376 LLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ-- 433
L K +V++ Y++KV+ + + G +SE T+ + E+ P PQ
Sbjct: 408 LDAKVPTERSAVLVNLKKG---VTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSV 464
Query: 434 -LVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWA 492
+++ S+NST+++V+W+P + G I K W N+ I
Sbjct: 465 TVLTVGSYNSTSISVSWDPPPPDHQ--NG--IIQEYKIWCLGNETRFHINKTVDAAIRSV 520
Query: 493 LIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+I GL P Y V+V A SAG G +SE
Sbjct: 521 IIGGLFPGIQYRVEVAASTSAGVGVKSE 548
Score = 58.4 bits (135), Expect = 8e-08
Identities = 54/218 (24%), Positives = 95/218 (43%), Gaps = 9/218 (4%)
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRL 468
DI P P V +++ V +L + T + VTW +D+ + ++G + +R
Sbjct: 338 DISP-PAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWT-VDRQPQFIQGYRVMYRQ 395
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFR 528
Q + + T R+ A++V L+ Y +KV + + +G +SE RT
Sbjct: 396 TSGLQATSSWQNLDAKVPTERS-AVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTE 454
Query: 529 KAPQKPPASV---NVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTI 585
+AP PP SV V +++ T++ V W P ++ + YK+ W L + +
Sbjct: 455 EAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI--WCLGNETRFHINKT 512
Query: 586 VPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
V + I + PG Y + V A ++ G G S P
Sbjct: 513 VDAAIR-SVIIGGLFPGIQYRVEVAASTSAGVGVKSEP 549
Score = 53.6 bits (123), Expect = 2e-06
Identities = 39/129 (30%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 91 DEGVYTCVAKNQYGTDESRGRLIV----LRAPRFLEKLPPRITAQVNSVVFLHCNADVDP 146
DEG Y C+A+N+ G E+ L V + P+F+ + +I AQ +V F C +P
Sbjct: 4 DEGTYMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTF-PCETKGNP 62
Query: 147 ILDTAYLWNHNGLR--IKDSSDLYVNKRIKID-GGELTIYNVSLSDVGDYECVVKSAIGR 203
A W G + + + N R + G+LTI N+ SD G Y C + G
Sbjct: 63 --QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGS 120
Query: 204 ISSHVQLRI 212
I + QL +
Sbjct: 121 ILAKAQLEV 129
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 114 bits (274), Expect = 1e-24
Identities = 122/496 (24%), Positives = 209/496 (42%), Gaps = 52/496 (10%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGG-----KRFITEN-GNLIIRQLSRDDEGVYTCVA 99
T+ C P P TW KD + + K+ +E+ G L I Q D+G Y CVA
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVA 203
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNS-------VVFLHCNADVDPILDTAY 152
N GT S + +R R + ++PPR + + V + C A P+ +
Sbjct: 204 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 263
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ L +D D+ + + + L + +V S +Y CV S +G I + Q+ +
Sbjct: 264 MLGAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEAIAQITV 313
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
+ P PPG + +S+TL W + N P++ Y++ + + Y + I V
Sbjct: 314 KALPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---KEIDGV- 367
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
RY+ L P++ YEFR+ A+N +G G PS P TS P AP +V
Sbjct: 368 ATTRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSSAPRDVQ 419
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS 392
+ + + W P NG Y++++ + ++ + K+ + + I
Sbjct: 420 ARMLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADSQITTIG 474
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPI 452
+ Y VKV AF IG GP S + + + +P P A + T++ ++W P
Sbjct: 475 NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSILLSWTPP 533
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
+ + L Y E+ EE+ I T+ + GL+P++ YY ++ A +
Sbjct: 534 RSD------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFRLAARSP 584
Query: 513 AGEGPESERYLERTFR 528
G G + RT +
Sbjct: 585 QGLGASTAEISARTMQ 600
Score = 93.9 bits (223), Expect = 2e-18
Identities = 149/619 (24%), Positives = 241/619 (38%), Gaps = 80/619 (12%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQ 131
+++ Q R DE +Y CVA N G RL VLR + P ++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 132 VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-GELTIYNVSLSDV 190
+ L C A +P D W + L + S++ K+++ + G L I SD
Sbjct: 140 TRTATML-CAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQ 196
Query: 191 GDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTLEWTDS 239
G YECV ++ G R S+ L + PP PP +I+ ++T S
Sbjct: 197 GKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS 256
Query: 240 NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRI 299
P +ML I N+ + +V + +ST + AI + +
Sbjct: 257 PM---PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITV 313
Query: 300 QAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIH 359
+A+ P P P ST+ +T+TW S P +
Sbjct: 314 KAL----PKPPGTPVVTESTATS------------------ITLTWD----SGNPEPVSY 347
Query: 360 YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP SE V
Sbjct: 348 YIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPV 402
Query: 420 TIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEE 479
++E P AP+ V AR +ST + V W + E G++ G+R+ Y +
Sbjct: 403 LTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDPTQHVN 458
Query: 480 CIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVN 539
+ I L P Y VKV+AF S G+GP S T P +P +N
Sbjct: 459 NWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP---LN 515
Query: 540 VWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNI 599
A + ++ + P + + Y++ + +D + + IE + +
Sbjct: 516 FKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGL 569
Query: 600 IPGKSYNLRVLAYSNGGDG 618
P Y R+ A S G G
Sbjct: 570 KPNSLYYFRLAARSPQGLG 588
Score = 74.9 bits (176), Expect = 8e-13
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query: 442 STALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+T++ +TW+ + E + +I H+ K ++ KE + + TTR + GL P +
Sbjct: 330 ATSITLTWD--SGNPEPVSYYIIQHKPKNSEELYKEIDGV----ATTRY--SVAGLSPYS 381
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE 561
Y +V+A N+ G GP SE L +T +AP P V TT+ V W+ +P
Sbjct: 382 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPN 439
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ GY+V + +D N + I N++P K+Y+++VLA+++ GDG +S
Sbjct: 440 GQIQGYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLS 498
Query: 622 S 622
S
Sbjct: 499 S 499
Score = 55.2 bits (127), Expect = 7e-07
Identities = 86/361 (23%), Positives = 138/361 (38%), Gaps = 42/361 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 199 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 256
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 257 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 313
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 314 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 363
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 364 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 423
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 424 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 473
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 474 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 531
Query: 347 P 347
P
Sbjct: 532 P 532
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 113 bits (273), Expect = 1e-24
Identities = 90/316 (28%), Positives = 145/316 (45%), Gaps = 24/316 (7%)
Query: 3 QCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTW 61
QCEA+N+ ++A + V+ L P+ K + +TY + +G L CK AP P+ W
Sbjct: 235 QCEARNRHGLLLANAYIYVVQL-PA-KILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQW 292
Query: 62 -KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+D + + F NG L IR L +D G Y C+A N L V A +
Sbjct: 293 LDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQI 352
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ I + + V F C A DP L + W +G +D +L + + I+ G L
Sbjct: 353 TQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDG---RDLQELGDSDKYFIEDGRL 408
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ---RSSVTLEWT 237
I+++ SD G+Y CV + + + S QL + G PGP + + + +S V + W+
Sbjct: 409 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWS 468
Query: 238 DSNSNGRPITGYML--TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIY 295
+ + PI Y + + WY + + +P G + +T + L P+ Y
Sbjct: 469 PAEDHNAPIEKYDIEFEDKEMAPEKWYSLGK-VP---------GNQTST-TLKLSPYVHY 517
Query: 296 EFRIQAINILGPGQPS 311
FR+ AIN GPG+PS
Sbjct: 518 TFRVTAINKYGPGEPS 533
Score = 56.4 bits (130), Expect = 3e-07
Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 6/172 (3%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
+G + L+C E P PT W + + + A + N L + ++ +D+G Y C+A+
Sbjct: 88 QGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
N G+ + V AP +L K P L C P W NG+
Sbjct: 148 NSLGSARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRP--QPEVTWRINGIP 204
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
++ +L +++ +I G L + NV SD +C ++ G + ++ + +
Sbjct: 205 VE---ELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 253
>AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 variant
protein.
Length = 1130
Score = 113 bits (272), Expect = 2e-24
Identities = 131/542 (24%), Positives = 226/542 (41%), Gaps = 59/542 (10%)
Query: 105 TDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
T E++ L V P FL K P I A + + C P W NG + S
Sbjct: 4 TIEAQAELTVQAQPEFL-KQPTNIYAHESMDIVFECEVTGKPT--PTVKWVKNGDMVIPS 60
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG-----PPGPP 219
+ K L + + SD G Y+C+ ++ +G + QL I P PP
Sbjct: 61 DYFKIVKE-----HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPP 115
Query: 220 GGVQILGIQRSSVTLEWTDSNSNGRPITGYM------LTGRT-----HWNSTWYVI---S 265
+ + ++ + + LT RT H ++ Y +
Sbjct: 116 TSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTK 175
Query: 266 ENIPNV-MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKP 324
E I +E + G + T+ L+P +Y FR+ A N G G+ SAP + T +
Sbjct: 176 EGIARERVENTSHPGEMQVTIQN-LMPATVYIFRVMAQNKHGSGESSAPL-RVETQPEVQ 233
Query: 325 YEAPA-NVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGN 383
PA N+ +T+TW P S NG +YK+++ G++ E Q + +
Sbjct: 234 LPGPAPNLRAYAASPTSITVTWET-PVS-GNGEIQNYKLYYMEKGTDKE-QDV------D 284
Query: 384 IGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNST 443
+ ++ I+ YT Y +V A+N GPG + V + + D+P APQ +S NS
Sbjct: 285 VSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSK 344
Query: 444 ALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYY 503
++ + W P + + G++ G++++Y K K + +S T + LI GL T Y
Sbjct: 345 SIMIHWQPPAPATQ--NGQITGYKIRYRKASRKSDVTETLVSGTQLS-QLIEGLDRGTEY 401
Query: 504 YVKVMAFNSAGEGPESERYLERTFR------KAPQKPPASVNVWAHDPTTLRVVWRYVQP 557
+V A G GP ++ TF + P+ P+S++V P +V + P
Sbjct: 402 NFRVAALTINGTGPATDWLSAETFESDLDETRVPE-VPSSLHV---RPLVTSIVVSWTPP 457
Query: 558 TNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGG 616
N+ + GY + + + + + +++K Y I N+ P Y + + A++N G
Sbjct: 458 ENQNIVVRGYAI-----GYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVG 512
Query: 617 DG 618
+G
Sbjct: 513 EG 514
Score = 83.8 bits (198), Expect = 2e-15
Identities = 97/390 (24%), Positives = 161/390 (41%), Gaps = 44/390 (11%)
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP-----GPPGGVQILGIQRSSVT 233
++TI N+ + V + + ++ G S LR+E P GP ++ +S+T
Sbjct: 193 QVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSIT 252
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWA 293
+ W S I Y L Y + + +VD + L +
Sbjct: 253 VTWETPVSGNGEIQNYKL----------YYMEKGTDKEQDVD---VSSHSYTINGLKKYT 299
Query: 294 IYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQ 353
Y FR+ A N GPG S P T D P AP N+S + + I W P + Q
Sbjct: 300 EYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQ 358
Query: 354 NGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH-ISSTYFYTPYDVKVQAFNDIGP 412
NG YKI +R+ + + L+ GT + I T Y+ +V A G
Sbjct: 359 NGQITGYKIRYRKASRKSDVTETLVS-----GTQLSQLIEGLDRGTEYNFRVAALTINGT 413
Query: 413 GPESEVVTIYSAE-DMPQV-APQLVSARSFNS--TALNVTWNPIDQSRERLRGKLIGHRL 468
GP ++ ++ + E D+ + P++ S+ T++ V+W P + +RG IG+ +
Sbjct: 414 GPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGI 473
Query: 469 KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG-PESERYLERTF 527
+ + + Y R + I L P ++Y + + AFN+ GEG P E + R
Sbjct: 474 ---GSPHAQTIKVDYKQR----YYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPH 526
Query: 528 R---KAPQKPPASV--NVWAHDPTTLRVVW 552
P PP V ++ +HD T+R+ W
Sbjct: 527 TVPDPTPMMPPVGVQASILSHD--TIRITW 554
Score = 60.1 bits (139), Expect = 3e-08
Identities = 33/112 (29%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Query: 15 SSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKR 74
+ A+L V + +P F K P + Y E ++ +C+ P PT W K+ ++
Sbjct: 7 AQAELTVQA-QPEFLKQPTNI--YAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYF 63
Query: 75 FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP 126
I + NL + L + DEG Y C+A+N G ++ +LI+L + LPP
Sbjct: 64 KIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPP 115
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/231 (24%), Positives = 97/231 (41%), Gaps = 16/231 (6%)
Query: 400 YDVKVQAFNDIGPG-P--ESEVVTIYSAED-MPQVAPQLVSARSFNSTALNVTW--NPID 453
Y + ++AFN++G G P ES V ++ D P + P V A + + +TW N +
Sbjct: 501 YVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRITWADNSLP 560
Query: 454 QSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSA 513
+ ++ + R WK + TT ++ L+ GL+P+T Y VM
Sbjct: 561 KHQKITDSRYYTVR---WKTNIPANTKYKNANATTLSY-LVTGLKPNTLYEFSVMVTKGR 616
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHD--PTTLRVVWRYVQPTNEEEPLLGYKVRL 571
S TF P PP V V + + P T+ V W+ P+ + GY +
Sbjct: 617 RSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQ--PPSEANGKITGY-IIY 673
Query: 572 WELDQDMSTANDTIVP-IEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ D + + I P + ++L I + Y ++ A ++ G G MS
Sbjct: 674 YSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMS 724
Score = 46.4 bits (105), Expect = 3e-04
Identities = 53/209 (25%), Positives = 81/209 (38%), Gaps = 18/209 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PP GVQ + ++ + W D N P +T ++ W NIP +
Sbjct: 533 PMMPPVGVQASILSHDTIRITWAD---NSLP-KHQKITDSRYYTVRW---KTNIPANTKY 585
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGD-KPYEAPANVS- 332
N + + T L P +YEF + G + T+ + P P +V+
Sbjct: 586 KNANATTLSYLVTGLKPNTLYEFSVMVTK--GRRSSTWSMTAHGTTFELVPTSPPKDVTV 643
Query: 333 -GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH- 390
GK + + W P S NG Y I++ + E +++ +G + H
Sbjct: 644 VSKEGKPKTIIVNWQ--PPSEANGKITGYIIYYSTD-VNAEIHDWVIEPV--VGNRLTHQ 698
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
I TPY K+QA N G GP SE V
Sbjct: 699 IQELTLDTPYYFKIQARNSKGMGPMSEAV 727
Score = 45.6 bits (103), Expect = 6e-04
Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 470 YWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRK 529
++ +E E + S I L P T Y +VMA N G G S T +
Sbjct: 172 FYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPE 231
Query: 530 APQKPPA-SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPI 588
PA ++ +A PT++ V W P + + YK L+ +++ D V
Sbjct: 232 VQLPGPAPNLRAYAASPTSITVTWE--TPVSGNGEIQNYK--LYYMEKGTDKEQDVDVS- 286
Query: 589 EHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQ-IGDYHSEA 636
H I+ + Y+ RV+AY+ G G +S+P +A + + D S A
Sbjct: 287 SHSYT--INGLKKYTEYSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAA 332
Score = 41.5 bits (93), Expect = 0.009
Identities = 69/305 (22%), Positives = 109/305 (35%), Gaps = 29/305 (9%)
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+S+ + WT + + GY + Y I ++VD ++R L
Sbjct: 448 TSIVVSWTPPENQNIVVRGYAIG---------YGIGSPHAQTIKVDY---KQRYYTIENL 495
Query: 290 LPWAIYEFRIQAINILGPGQP---SAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
P + Y ++A N +G G P SA + + P P V + ITW
Sbjct: 496 DPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRITWA 555
Query: 347 P--LPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
LP + +Y + W+ N + K N T ++ T Y+ V
Sbjct: 556 DNSLPKHQKITDSRYYTVRWKTN-----IPANTKYKNANATTLSYLVTGLKPNTLYEFSV 610
Query: 405 QAFNDIGPGPESEVVTIYSAEDMPQVAPQLVS--ARSFNSTALNVTWNPIDQSRERLRGK 462
S + E +P P+ V+ ++ + V W P ++ GK
Sbjct: 611 MVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVNWQPPSEAN----GK 666
Query: 463 LIGHRLKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESER 521
+ G+ + Y N E + + R I L DT YY K+ A NS G GP SE
Sbjct: 667 ITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEA 726
Query: 522 YLERT 526
RT
Sbjct: 727 VQFRT 731
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 111 bits (268), Expect = 6e-24
Identities = 143/584 (24%), Positives = 238/584 (40%), Gaps = 65/584 (11%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGG-----KRFITEN-GNLIIRQLSRDDEGVYTCVA 99
T+ C P P TW KD + + K+ +E+ G L I Q D+G Y CVA
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVA 203
Query: 100 KNQYGTDESRGRLIVLRA----PRFLEKLPP-RITAQVNSVVFLHCNADVDPILDTAYLW 154
N GT S + +R PRF +PP V + C A P+ ++
Sbjct: 204 TNSAGTRYSAPANLYVRVRRVPPRF--SIPPTNHEIMPGGSVNITCVAVGSPMPYVKWML 261
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
L +D D+ + + + L + +V S +Y CV S +G I + Q+ ++
Sbjct: 262 GAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKA 311
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PPG + +S+TL W + N P++ Y++ + + Y + I V
Sbjct: 312 LPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---KEIDGV-AT 365
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
RY+ L P++ YEFR+ A+N +G G PS P TS P AP +V
Sbjct: 366 TRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSSAPRDVQAR 417
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISST 394
+ + + W P NG Y++++ + ++ + K+ + + I +
Sbjct: 418 MLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADSQITTIGNL 472
Query: 395 YFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQ 454
Y VKV AF IG GP S + + + +P P A + T++ ++W P
Sbjct: 473 VPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSILLSWTPPRS 531
Query: 455 SRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAG 514
+ + L Y E+ EE+ I T+ + GL+P++ YY ++ A + G
Sbjct: 532 D------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFRLAARSPQG 582
Query: 515 EGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWEL 574
G + RT + K + +V A T++ + W + N P +K+ L
Sbjct: 583 LGASTAEISARTMQSMFAK---NFHVKAVMKTSVLLSWEIPENYNSAMP---FKI----L 632
Query: 575 DQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D + KL I N+ P KSY+ + N G
Sbjct: 633 YDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 673
Score = 96.7 bits (230), Expect = 2e-19
Identities = 149/614 (24%), Positives = 241/614 (39%), Gaps = 74/614 (12%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-GELTIYNVSLSDVG 191
+ C A +P D W + L + S++ K+++ + G L I SD G
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQG 197
Query: 192 DYECVVKSAIG-RISSHVQLRI---EGPPG---PPGGVQILGIQRSSVTLEWTDSNSNGR 244
YECV ++ G R S+ L + PP PP +I+ ++T S
Sbjct: 198 KYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS---PM 254
Query: 245 PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINI 304
P +ML I N+ + +V + +ST + AI + ++A+
Sbjct: 255 PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKAL-- 312
Query: 305 LGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFW 364
P P P ST+ +T+TW S P +Y I
Sbjct: 313 --PKPPGTPVVTESTA------------------TSITLTW----DSGNPEPVSYYIIQH 348
Query: 365 RRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSA 424
+ SE L K+ + T ++ Y+ Y+ +V A N+IG GP SE V ++
Sbjct: 349 KPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTS 403
Query: 425 EDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYL 484
E P AP+ V AR +ST + V W + E G++ G+R+ Y +
Sbjct: 404 EQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDPTQHVNNWMKH 459
Query: 485 SRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHD 544
+ I L P Y VKV+AF S G+GP S T P +P +N A
Sbjct: 460 NVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP---LNFKAEP 516
Query: 545 PTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKS 604
+ ++ + P + + Y++ + +D + + IE + + P
Sbjct: 517 ESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSL 570
Query: 605 YNLRVLAYSNGGDG 618
Y R+ A S G G
Sbjct: 571 YYFRLAARSPQGLG 584
Score = 74.9 bits (176), Expect = 8e-13
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query: 442 STALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+T++ +TW+ + E + +I H+ K ++ KE + + TTR + GL P +
Sbjct: 326 ATSITLTWD--SGNPEPVSYYIIQHKPKNSEELYKEIDGV----ATTRY--SVAGLSPYS 377
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE 561
Y +V+A N+ G GP SE L +T +AP P V TT+ V W+ +P
Sbjct: 378 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPN 435
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ GY+V + +D N + I N++P K+Y+++VLA+++ GDG +S
Sbjct: 436 GQIQGYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLS 494
Query: 622 S 622
S
Sbjct: 495 S 495
Score = 58.4 bits (135), Expect = 8e-08
Identities = 84/357 (23%), Positives = 137/357 (38%), Gaps = 38/357 (10%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YS+ +RV + P F P E GG+V + C +P P
Sbjct: 199 YECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGSPMPY 256
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W + I N ++ YTCVA + G E+ ++ V P
Sbjct: 257 VKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALP 313
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ P + S+ + + +P+ + Y+ H + K+S +LY +IDG
Sbjct: 314 K-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----EIDGV 363
Query: 179 ELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGIQRSS 231
T Y+V+ LS DYE V + IGR S V Q + P P VQ + ++
Sbjct: 364 ATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTT 423
Query: 232 VTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVSTTLL 290
+ ++W + I GY + Y + +V ++N + T L+
Sbjct: 424 ILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTIGNLV 473
Query: 291 PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
P Y ++ A +G G P + Q T P + P N + ++WTP
Sbjct: 474 PQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWTP 528
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 111 bits (267), Expect = 8e-24
Identities = 105/394 (26%), Positives = 174/394 (44%), Gaps = 35/394 (8%)
Query: 47 LKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L+C P+P +W + D IG G + + GNLII ++ GVY C A N+ GT
Sbjct: 257 LECVATGNPRPIVSWSRLDGRPIGVEGIQ-VLGTGNLIISDVTVQHSGVYVCAA-NRPGT 314
Query: 106 DESR---GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
R GRL+V +AP + P I+ + C A +P W NG +
Sbjct: 315 RVRRTAQGRLVV-QAPAEFVQHPQSISRPAGTTAMFTCQAQGEP--PPHVTWLKNGQVLG 371
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---EGPPGPP 219
+ R+K + LTI + D Y+CV +++ G + +L + EG PGPP
Sbjct: 372 PGGHV----RLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPP 427
Query: 220 GGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNG 279
V+ + + + V + W++ +N + I GY+L R + + P + + +
Sbjct: 428 RNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRK---------AADPPELEYQEAVSK 478
Query: 280 RKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTG 339
+ + L P Y F I+A G S P+ ST G+ P P +V G +
Sbjct: 479 STFQHLVSDLEPSTAYSFYIKAYTPRGASSASVPT-LASTLGEAPAPPPLSVRVLG--SS 535
Query: 340 DLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTP 399
L + W P P Q+ G +K+F+ R S+ F +L G + +Y ++S
Sbjct: 536 SLQLLWEPWPRLAQHEGG--FKLFY-RPASKTSFTGPILLP-GTVSSY--NLSQLDPTAV 589
Query: 400 YDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAP 432
Y+VK+ A+N G G + V++ A + ++P
Sbjct: 590 YEVKLLAYNQHGDGNATVRFVSLRGASERTALSP 623
Score = 76.6 bits (180), Expect = 3e-13
Identities = 123/526 (23%), Positives = 200/526 (38%), Gaps = 34/526 (6%)
Query: 2 YQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+C A+N+ S A+++ ++ F HP T G EGG +C+ PKP T
Sbjct: 115 YECVAQNRFGLVVSRKARIQAATMS-DFHVHPQA--TVGEEGGVARFQCQIHGLPKPLIT 171
Query: 61 WKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG-RLIVLRAP 118
W+K+ + I +R+ + G L I L +D G++ CVA N S G RL V +
Sbjct: 172 WEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSG 231
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
K P + N + +H A ++ + + R+ D + V + G
Sbjct: 232 SGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL-DGRPIGVEGIQVLGTG 290
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ-ILGIQRSSVTLEWT 237
L I +V++ G Y C R+ Q R+ P VQ I R + T
Sbjct: 291 NLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLV-VQAPAEFVQHPQSISRPAGTTAMF 349
Query: 238 DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
+ G P + TW + + V N T+S + P +
Sbjct: 350 TCQAQGEPPP----------HVTWLKNGQVLGPGGHVRLKNNNSTLTIS-GIGPEDEAIY 398
Query: 298 RIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPG 357
+ A N G Q SA G P P NV + ++ ++W+ + + G
Sbjct: 399 QCVAENSAGSSQASARLTVLWAEG-LP-GPPRNVRAVSVSSTEVRVSWSEPLANTKEIIG 456
Query: 358 IHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESE 417
I + E+E+Q + K T+ +S T Y ++A+ G S
Sbjct: 457 YVLHIRKAADPPELEYQEAVSK-----STFQHLVSDLEPSTAYSFYIKAYTPRGASSASV 511
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+ + P AP +S R S++L + W P RL G +L Y
Sbjct: 512 PTLASTLGEAP--APPPLSVRVLGSSSLQLLWEP----WPRLAQHEGGFKLFYRPASKTS 565
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
L T ++ L L P Y VK++A+N G+G + R++
Sbjct: 566 FTGPILLPGTVSSYNL-SQLDPTAVYEVKLLAYNQHGDGNATVRFV 610
Score = 63.3 bits (147), Expect = 3e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPS-FKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y C A +AQ R++ P+ F +HP + G C+ + P P
Sbjct: 304 VYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISR--PAGTTAMFTCQAQGEPPPHV 361
Query: 60 TWKKDNIVIGAGGK-RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
TW K+ V+G GG R N L I + +DE +Y CVA+N G+ ++ RL VL A
Sbjct: 362 TWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWA 420
Score = 58.4 bits (135), Expect = 8e-08
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 406 AFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN-PIDQSRERLRGKLI 464
A N G S +T+ AE +P P+ V A S +ST + V+W+ P+ ++E +I
Sbjct: 402 AENSAGSSQASARLTVLWAEGLPG-PPRNVRAVSVSSTEVRVSWSEPLANTKE-----II 455
Query: 465 GHRLKYWKQENKEE-ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
G+ L K + E E +S++T L+ L+P T Y + A+ G S L
Sbjct: 456 GYVLHIRKAADPPELEYQEAVSKSTFQH-LVSDLEPSTAYSFYIKAYTPRGASSASVPTL 514
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
T +AP PP SV V ++L+++W + E G+K+ + S
Sbjct: 515 ASTLGEAPAPPPLSVRVLG--SSSLQLLWEPWPRLAQHEG--GFKL-FYRPASKTSFTGP 569
Query: 584 TIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
++P + +Y +S + P Y +++LAY+ GDG
Sbjct: 570 ILLP--GTVSSYNLSQLDPTAVYEVKLLAYNQHGDG 603
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 13/180 (7%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQL------SRDDEGVY 95
G + L C+ E P TW+K+ + + + NG+L+IR S DEG Y
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115
Query: 96 TCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWN 155
CVA+N++G SR I P + V C + + W
Sbjct: 116 ECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC--QIHGLPKPLITWE 173
Query: 156 HNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS-AIGRISSHVQLRIEG 214
N + I ++ Y + G L I + D G + CV + A RIS +L + G
Sbjct: 174 KNRVPIDTDNERYT----LLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSG 229
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 494 IVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWR 553
I G+ P+ + +A NSAG S R L + + PP +V + T +RV W
Sbjct: 387 ISGIGPEDEAIYQCVAENSAGSSQASAR-LTVLWAEGLPGPPRNVRAVSVSSTEVRVSWS 445
Query: 554 YVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYS 613
+P + ++GY + + + V + + +S++ P +Y+ + AY+
Sbjct: 446 --EPLANTKEIIGYVLHIRKAADPPELEYQEAVS-KSTFQHLVSDLEPSTAYSFYIKAYT 502
Query: 614 NGGDGRMSSPTIAFQIGD 631
G S PT+A +G+
Sbjct: 503 PRGASSASVPTLASTLGE 520
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 111 bits (267), Expect = 8e-24
Identities = 105/394 (26%), Positives = 174/394 (44%), Gaps = 35/394 (8%)
Query: 47 LKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L+C P+P +W + D IG G + + GNLII ++ GVY C A N+ GT
Sbjct: 257 LECVATGNPRPIVSWSRLDGRPIGVEGIQ-VLGTGNLIISDVTVQHSGVYVCAA-NRPGT 314
Query: 106 DESR---GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
R GRL+V +AP + P I+ + C A +P W NG +
Sbjct: 315 RVRRTAQGRLVV-QAPAEFVQHPQSISRPAGTTAMFTCQAQGEP--PPHVTWLKNGQVLG 371
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---EGPPGPP 219
+ R+K + LTI + D Y+CV +++ G + +L + EG PGPP
Sbjct: 372 PGGHV----RLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPP 427
Query: 220 GGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNG 279
V+ + + + V + W++ +N + I GY+L R + + P + + +
Sbjct: 428 RNVRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRK---------AADPPELEYQEAVSK 478
Query: 280 RKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTG 339
+ + L P Y F I+A G S P+ ST G+ P P +V G +
Sbjct: 479 STFQHLVSDLEPSTAYSFYIKAYTPRGASSASVPT-LASTLGEAPAPPPLSVRVLG--SS 535
Query: 340 DLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTP 399
L + W P P Q+ G +K+F+ R S+ F +L G + +Y ++S
Sbjct: 536 SLQLLWEPWPRLAQHEGG--FKLFY-RPASKTSFTGPILLP-GTVSSY--NLSQLDPTAV 589
Query: 400 YDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAP 432
Y+VK+ A+N G G + V++ A + ++P
Sbjct: 590 YEVKLLAYNQHGDGNATVRFVSLRGASERTALSP 623
Score = 76.6 bits (180), Expect = 3e-13
Identities = 123/526 (23%), Positives = 200/526 (38%), Gaps = 34/526 (6%)
Query: 2 YQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+C A+N+ S A+++ ++ F HP T G EGG +C+ PKP T
Sbjct: 115 YECVAQNRFGLVVSRKARIQAATMS-DFHVHPQA--TVGEEGGVARFQCQIHGLPKPLIT 171
Query: 61 WKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG-RLIVLRAP 118
W+K+ + I +R+ + G L I L +D G++ CVA N S G RL V +
Sbjct: 172 WEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSG 231
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
K P + N + +H A ++ + + R+ D + V + G
Sbjct: 232 SGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL-DGRPIGVEGIQVLGTG 290
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ-ILGIQRSSVTLEWT 237
L I +V++ G Y C R+ Q R+ P VQ I R + T
Sbjct: 291 NLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLV-VQAPAEFVQHPQSISRPAGTTAMF 349
Query: 238 DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
+ G P + TW + + V N T+S + P +
Sbjct: 350 TCQAQGEPPP----------HVTWLKNGQVLGPGGHVRLKNNNSTLTIS-GIGPEDEAIY 398
Query: 298 RIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPG 357
+ A N G Q SA G P P NV + ++ ++W+ + + G
Sbjct: 399 QCVAENSAGSSQASARLTVLWAEG-LP-GPPRNVRAVSVSSTEVRVSWSEPLANTKEIIG 456
Query: 358 IHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESE 417
I + E+E+Q + K T+ +S T Y ++A+ G S
Sbjct: 457 YVLHIRKAADPPELEYQEAVSK-----STFQHLVSDLEPSTAYSFYIKAYTPRGASSASV 511
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+ + P AP +S R S++L + W P RL G +L Y
Sbjct: 512 PTLASTLGEAP--APPPLSVRVLGSSSLQLLWEP----WPRLAQHEGGFKLFYRPASKTS 565
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
L T ++ L L P Y VK++A+N G+G + R++
Sbjct: 566 FTGPILLPGTVSSYNL-SQLDPTAVYEVKLLAYNQHGDGNATVRFV 610
Score = 63.3 bits (147), Expect = 3e-09
Identities = 38/119 (31%), Positives = 56/119 (47%), Gaps = 4/119 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPS-FKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y C A +AQ R++ P+ F +HP + G C+ + P P
Sbjct: 304 VYVCAANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISR--PAGTTAMFTCQAQGEPPPHV 361
Query: 60 TWKKDNIVIGAGGK-RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
TW K+ V+G GG R N L I + +DE +Y CVA+N G+ ++ RL VL A
Sbjct: 362 TWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWA 420
Score = 58.4 bits (135), Expect = 8e-08
Identities = 60/216 (27%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 406 AFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN-PIDQSRERLRGKLI 464
A N G S +T+ AE +P P+ V A S +ST + V+W+ P+ ++E +I
Sbjct: 402 AENSAGSSQASARLTVLWAEGLPG-PPRNVRAVSVSSTEVRVSWSEPLANTKE-----II 455
Query: 465 GHRLKYWKQENKEE-ECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
G+ L K + E E +S++T L+ L+P T Y + A+ G S L
Sbjct: 456 GYVLHIRKAADPPELEYQEAVSKSTFQH-LVSDLEPSTAYSFYIKAYTPRGASSASVPTL 514
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
T +AP PP SV V ++L+++W + E G+K+ + S
Sbjct: 515 ASTLGEAPAPPPLSVRVLG--SSSLQLLWEPWPRLAQHEG--GFKL-FYRPASKTSFTGP 569
Query: 584 TIVPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
++P + +Y +S + P Y +++LAY+ GDG
Sbjct: 570 ILLP--GTVSSYNLSQLDPTAVYEVKLLAYNQHGDG 603
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 13/180 (7%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQL------SRDDEGVY 95
G + L C+ E P TW+K+ + + + NG+L+IR S DEG Y
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEPGGSPSDEGDY 115
Query: 96 TCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWN 155
CVA+N++G SR I P + V C + + W
Sbjct: 116 ECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC--QIHGLPKPLITWE 173
Query: 156 HNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS-AIGRISSHVQLRIEG 214
N + I ++ Y + G L I + D G + CV + A RIS +L + G
Sbjct: 174 KNRVPIDTDNERYT----LLPKGVLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSG 229
Score = 44.0 bits (99), Expect = 0.002
Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 494 IVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWR 553
I G+ P+ + +A NSAG S R L + + PP +V + T +RV W
Sbjct: 387 ISGIGPEDEAIYQCVAENSAGSSQASAR-LTVLWAEGLPGPPRNVRAVSVSSTEVRVSWS 445
Query: 554 YVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYS 613
+P + ++GY + + + V + + +S++ P +Y+ + AY+
Sbjct: 446 --EPLANTKEIIGYVLHIRKAADPPELEYQEAVS-KSTFQHLVSDLEPSTAYSFYIKAYT 502
Query: 614 NGGDGRMSSPTIAFQIGD 631
G S PT+A +G+
Sbjct: 503 PRGASSASVPTLASTLGE 520
>X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 1523
Score = 111 bits (266), Expect = 1e-23
Identities = 94/343 (27%), Positives = 153/343 (44%), Gaps = 26/343 (7%)
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPL 348
L P ++Y FR+ A + G G +A T KP P ++S + + ++W P
Sbjct: 186 LKPNSLYYFRLAARSPQGLGASTAEISA-RTMQSKPSAPPQDISCTSPSSTSILVSWQPP 244
Query: 349 PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFN 408
P QNG Y I + E + +L + Y+ + +T Y + V A
Sbjct: 245 PVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL--LEQLEKWTEYRITVTAHT 302
Query: 409 DIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHR 467
D+GPGPES V I + ED+P P+ V + NST++ V+W +P+ + G++ G++
Sbjct: 303 DVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQ---HGQIRGYQ 359
Query: 468 LKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ Y + EN E + + TT + +I GLQP+T Y + V A+ + G+
Sbjct: 360 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGD 419
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
G S+ L T P KP +N T + W P + PL GY+++ D
Sbjct: 420 GARSKPKLVSTTGAVPGKPRLVIN--HTQMNTALIQWH--PPVDTFGPLQGYRLKFGRKD 475
Query: 576 QDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ T T+ E + ++I G SY R+ A + G G
Sbjct: 476 MEPLT---TLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 515
Score = 99.5 bits (237), Expect = 3e-20
Identities = 102/435 (23%), Positives = 180/435 (41%), Gaps = 45/435 (10%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
+ P P VQ + +++ ++W + I GY + Y + +V
Sbjct: 26 QAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVN 75
Query: 273 EVDRYN-GRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANV 331
++N + T L+P Y ++ A +G G P + Q T P + P N
Sbjct: 76 NWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNF 133
Query: 332 SGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHI 391
+ ++WTP P S +Y++ + ++G E Q + ++ + +
Sbjct: 134 KAEPESETSILLSWTP-PRS---DTIANYELVY-KDGEHGEEQRITIEPGTSYRLQGLKP 188
Query: 392 SSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNP 451
+S Y++ ++ A + G G + ++ + + P PQ +S S +ST++ V+W P
Sbjct: 189 NSLYYF-----RLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQP 243
Query: 452 IDQSRERLRGKLIGHRLKYWK---QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
E+ G + + +KY +++K E + S TT+ L+ L+ T Y + V
Sbjct: 244 --PPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTK--YLLEQLEKWTEYRITVT 299
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A G GPES L RT P PP V V A + T+++V WR P + + GY+
Sbjct: 300 AHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQ 359
Query: 569 VRLWELDQDMSTANDTIVPI-------------EHKLEAYISNIIPGKSYNLRVLAYSNG 615
V ++ + + EH + IS + P SY+L V AY+
Sbjct: 360 VHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEH--DMIISGLQPETSYSLTVTAYTTK 417
Query: 616 GDGRMSSPTIAFQIG 630
GDG S P + G
Sbjct: 418 GDGARSKPKLVSTTG 432
Score = 79.0 bits (186), Expect = 5e-14
Identities = 70/323 (21%), Positives = 134/323 (41%), Gaps = 16/323 (4%)
Query: 296 EFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
EFR+ A+N +G G PS P TS P AP +V + + + W P NG
Sbjct: 1 EFRVVAVNNIGRGPPSEPVLT-QTSEQAPSSAPRDVQARMLSSTTILVQWKE-PEE-PNG 57
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPE 415
Y++++ + ++ + K+ + + I + Y VKV AF IG GP
Sbjct: 58 QIQGYRVYYTMDPTQHVNNWM---KHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 114
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S + + + +P P A + T++ ++W P + + L Y E+
Sbjct: 115 SSDIQVITQTGVPG-QPLNFKAEPESETSILLSWTPPRSDT------IANYELVYKDGEH 167
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPP 535
EE+ I T+ + GL+P++ YY ++ A + G G + RT + P PP
Sbjct: 168 GEEQRITIEPGTSYR---LQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPP 224
Query: 536 ASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY 595
++ + T++ V W+ + + Y ++ +D + ++ + +
Sbjct: 225 QDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYL 284
Query: 596 ISNIIPGKSYNLRVLAYSNGGDG 618
+ + Y + V A+++ G G
Sbjct: 285 LEQLEKWTEYRITVTAHTDVGPG 307
Score = 64.5 bits (150), Expect = 1e-09
Identities = 37/117 (31%), Positives = 60/117 (51%), Gaps = 3/117 (2%)
Query: 506 KVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLL 565
+V+A N+ G GP SE L +T +AP P V TT+ V W+ +P +
Sbjct: 3 RVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPNGQIQ 60
Query: 566 GYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
GY+V + +D N + I N++P K+Y+++VLA+++ GDG +SS
Sbjct: 61 GYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSS 116
Score = 55.6 bits (128), Expect = 5e-07
Identities = 99/410 (24%), Positives = 155/410 (37%), Gaps = 32/410 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V++ + +SV + W N I GY + N + +VM
Sbjct: 322 PSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKG-QPMLKDVM 380
Query: 273 EVDRY----NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAP 328
D + + + + L P Y + A G G S P ST+G P +
Sbjct: 381 LADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPK-LVSTTGAVPGKPR 439
Query: 329 ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
++ T I W P + GP Y++ + R E +K +
Sbjct: 440 LVINHTQMNTA--LIQWHPPVDTF--GPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATD 495
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+H ++Y + ++ A N +G G E V I E++P PQ + + ST++ ++
Sbjct: 496 IHKGASYVF-----RLSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLS 549
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVM 508
W P ER G + + L Y + N + L + GL+PDT Y VKV
Sbjct: 550 WQP-PVLAER-NGIITKYTLLY-RDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVR 606
Query: 509 AFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYK 568
A S G GP S RT Q + +V A T++ + W + N P +K
Sbjct: 607 AHTSKGPGPYSPSVQFRTL-PVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMP---FK 662
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ L D + KL I N+ P KSY+ + N G
Sbjct: 663 I----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 705
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 111 bits (266), Expect = 1e-23
Identities = 142/592 (23%), Positives = 241/592 (40%), Gaps = 71/592 (11%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGG-----KRFITEN-------GNLIIRQLSRDDEG 93
T+ C P P TW KD + + K+ +E+ G L I Q D+G
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQG 203
Query: 94 VYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNS-------VVFLHCNADVDP 146
Y CVA N GT S + +R R + ++PPR + + V + C A P
Sbjct: 204 KYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 263
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ ++ L +D D+ + + + L + +V S +Y CV S +G I +
Sbjct: 264 MPYVKWMLGAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEA 313
Query: 207 HVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISE 266
Q+ ++ P PPG + +S+TL W + N P++ Y++ + + Y +
Sbjct: 314 IAQITVKALPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---K 368
Query: 267 NIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYE 326
I V RY+ L P++ YEFR+ A+N +G G PS P TS P
Sbjct: 369 EIDGV-ATTRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSS 419
Query: 327 APANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGT 386
AP +V + + + W P NG Y++++ + ++ + K+ +
Sbjct: 420 APRDVQARMLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADS 474
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALN 446
+ I + Y VKV AF IG GP S + + + +P P A + T++
Sbjct: 475 QITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSIL 533
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
++W P + + L Y E+ EE+ I T+ + GL+P++ YY +
Sbjct: 534 LSWTPPRSD------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFR 584
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+ A + G G + RT + K + +V A T++ + W + N P
Sbjct: 585 LAARSPQGLGASTAEISARTMQSMFAK---NFHVKAVMKTSVLLSWEIPENYNSAMP--- 638
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+K+ L D + KL I N+ P KSY+ + N G
Sbjct: 639 FKI----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 683
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 74.9 bits (176), Expect = 8e-13
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query: 442 STALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+T++ +TW+ + E + +I H+ K ++ KE + + TTR + GL P +
Sbjct: 336 ATSITLTWD--SGNPEPVSYYIIQHKPKNSEELYKEIDGV----ATTRY--SVAGLSPYS 387
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE 561
Y +V+A N+ G GP SE L +T +AP P V TT+ V W+ +P
Sbjct: 388 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPN 445
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ GY+V + +D N + I N++P K+Y+++VLA+++ GDG +S
Sbjct: 446 GQIQGYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLS 504
Query: 622 S 622
S
Sbjct: 505 S 505
Score = 55.2 bits (127), Expect = 7e-07
Identities = 86/361 (23%), Positives = 138/361 (38%), Gaps = 42/361 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 P 347
P
Sbjct: 538 P 538
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 111 bits (266), Expect = 1e-23
Identities = 142/592 (23%), Positives = 241/592 (40%), Gaps = 71/592 (11%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGG-----KRFITEN-------GNLIIRQLSRDDEG 93
T+ C P P TW KD + + K+ +E+ G L I Q D+G
Sbjct: 144 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQG 203
Query: 94 VYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNS-------VVFLHCNADVDP 146
Y CVA N GT S + +R R + ++PPR + + V + C A P
Sbjct: 204 KYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 263
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ ++ L +D D+ + + + L + +V S +Y CV S +G I +
Sbjct: 264 MPYVKWMLGAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEA 313
Query: 207 HVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISE 266
Q+ ++ P PPG + +S+TL W + N P++ Y++ + + Y +
Sbjct: 314 IAQITVKALPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---K 368
Query: 267 NIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYE 326
I V RY+ L P++ YEFR+ A+N +G G PS P TS P
Sbjct: 369 EIDGV-ATTRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSS 419
Query: 327 APANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGT 386
AP +V + + + W P NG Y++++ + ++ + K+ +
Sbjct: 420 APRDVQARMLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADS 474
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALN 446
+ I + Y VKV AF IG GP S + + + +P P A + T++
Sbjct: 475 QITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSIL 533
Query: 447 VTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVK 506
++W P + + L Y E+ EE+ I T+ + GL+P++ YY +
Sbjct: 534 LSWTPPRSD------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFR 584
Query: 507 VMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLG 566
+ A + G G + RT + K + +V A T++ + W + N P
Sbjct: 585 LAARSPQGLGASTAEISARTMQSMFAK---NFHVKAVMKTSVLLSWEIPENYNSAMP--- 638
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+K+ L D + KL I N+ P KSY+ + N G
Sbjct: 639 FKI----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 683
Score = 89.0 bits (211), Expect = 5e-17
Identities = 149/624 (23%), Positives = 241/624 (38%), Gaps = 84/624 (13%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NG 80
P F + P++ +T G GG + C+ P+P W K + +RF + E +G
Sbjct: 24 PRFTRTPVD-QT-GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSG 79
Query: 81 NLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
+++ Q R DE +Y CVA N G RL VLR + P P++ +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVER 139
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG-------GELTIYNV 185
+ C A +P D W + L + S++ K+++ + G L I
Sbjct: 140 TRTATMLCAASGNP--DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 186 SLSDVGDYECVVKSAIG-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTL 234
SD G YECV ++ G R S+ L + PP PP +I+ ++T
Sbjct: 198 EESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 235 EWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI 294
S P +ML I N+ + +V + +ST + AI
Sbjct: 258 VAVGS---PMPYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAI 314
Query: 295 YEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQN 354
+ ++A+ P P P ST+ +T+TW S
Sbjct: 315 AQITVKAL----PKPPGTPVVTESTA------------------TSITLTW----DSGNP 348
Query: 355 GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGP 414
P +Y I + SE L K+ + T ++ Y+ Y+ +V A N+IG GP
Sbjct: 349 EPVSYYIIQHKPKNSEE-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGP 403
Query: 415 ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQE 474
SE V ++E P AP+ V AR +ST + V W + E G++ G+R+ Y
Sbjct: 404 PSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDP 459
Query: 475 NKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
+ + I L P Y VKV+AF S G+GP S T P +P
Sbjct: 460 TQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 519
Query: 535 PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEA 594
+N A + ++ + P + + Y++ + +D + + IE
Sbjct: 520 ---LNFKAEPESETSILLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSY 570
Query: 595 YISNIIPGKSYNLRVLAYSNGGDG 618
+ + P Y R+ A S G G
Sbjct: 571 RLQGLKPNSLYYFRLAARSPQGLG 594
Score = 74.9 bits (176), Expect = 8e-13
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query: 442 STALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+T++ +TW+ + E + +I H+ K ++ KE + + TTR + GL P +
Sbjct: 336 ATSITLTWD--SGNPEPVSYYIIQHKPKNSEELYKEIDGV----ATTRY--SVAGLSPYS 387
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE 561
Y +V+A N+ G GP SE L +T +AP P V TT+ V W+ +P
Sbjct: 388 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPN 445
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ GY+V + +D N + I N++P K+Y+++VLA+++ GDG +S
Sbjct: 446 GQIQGYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLS 504
Query: 622 S 622
S
Sbjct: 505 S 505
Score = 55.2 bits (127), Expect = 7e-07
Identities = 86/361 (23%), Positives = 138/361 (38%), Gaps = 42/361 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 205 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 262
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 263 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 319
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 320 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 369
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 370 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 429
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 430 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 479
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 480 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 537
Query: 347 P 347
P
Sbjct: 538 P 538
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 110 bits (265), Expect = 1e-23
Identities = 140/589 (23%), Positives = 237/589 (40%), Gaps = 68/589 (11%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITEN---------GNLIIRQLSRDDEGVYT 96
T+ C P P TW KD + + + G L I Q D+G Y
Sbjct: 120 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYE 179
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNS-------VVFLHCNADVDPILD 149
CVA N GT S + +R R + ++PPR + + V + C A P+
Sbjct: 180 CVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPY 239
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ 209
++ L +D D+ + + + L + +V S +Y CV S +G I + Q
Sbjct: 240 VKWMLGAEDLTPED--DMPIGRNV------LELNDVRQS--ANYTCVAMSTLGVIEAIAQ 289
Query: 210 LRIEGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIP 269
+ ++ P PPG + +S+TL W + N P++ Y++ + + Y + I
Sbjct: 290 ITVKALPKPPGTPVVTESTATSITLTW--DSGNPEPVSYYIIQHKPKNSEELY---KEID 344
Query: 270 NVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPA 329
V RY+ L P++ YEFR+ A+N +G G PS P TS P AP
Sbjct: 345 GV-ATTRYS-------VAGLSPYSDYEFRVVAVNNIGRGPPSEP-VLTQTSEQAPSSAPR 395
Query: 330 NVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
+V + + + W P NG Y++++ + ++ + K+ + +
Sbjct: 396 DVQARMLSSTTILVQWKE-PEE-PNGQIQGYRVYYTMDPTQHVNNWM---KHNVADSQIT 450
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW 449
I + Y VKV AF IG GP S + + + +P P A + T++ ++W
Sbjct: 451 TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG-QPLNFKAEPESETSILLSW 509
Query: 450 NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMA 509
P + + L Y E+ EE+ I T+ + GL+P++ YY ++ A
Sbjct: 510 TPPRSD------TIANYELVYKDGEHGEEQRITIEPGTSYR---LQGLKPNSLYYFRLAA 560
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
+ G G + RT + K + +V A T++ + W + N P +K+
Sbjct: 561 RSPQGLGASTAEISARTMQSMFAK---NFHVKAVMKTSVLLSWEIPENYNSAMP---FKI 614
Query: 570 RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
L D + KL I N+ P KSY+ + N G
Sbjct: 615 ----LYDDGKMVEEVDGRATQKL---IVNLKPEKSYSFVLTNRGNSAGG 656
Score = 90.2 bits (214), Expect = 2e-17
Identities = 146/608 (24%), Positives = 233/608 (38%), Gaps = 79/608 (12%)
Query: 39 GSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITE----NGNLIIRQLSRD--D 91
G GG + C+ P+P W K + +RF + E +G+++ Q R D
Sbjct: 11 GVSGGVASFICQATGDPRPKIVWNKKGKKVS--NQRFEVIEFDDGSGSVLRIQPLRTPRD 68
Query: 92 EGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQVNSVVFLHCNADVD 145
E +Y CVA N G RL VLR + P P++ + + C A +
Sbjct: 69 EAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGN 128
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG----GELTIYNVSLSDVGDYECVVKSAI 201
P D W + L + S++ K+++ G G L I SD G YECV ++
Sbjct: 129 P--DPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSA 186
Query: 202 G-RISSHVQLRIEG-------PPG---PPGGVQILGIQRSSVTLEWTDSNSNGRPITGYM 250
G R S+ L + PP PP +I+ ++T S P +M
Sbjct: 187 GTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS---PMPYVKWM 243
Query: 251 LTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQP 310
L I N+ + +V + +ST + AI + ++A+ P P
Sbjct: 244 LGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKAL----PKPP 299
Query: 311 SAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSE 370
P ST+ +T+TW S P +Y I + SE
Sbjct: 300 GTPVVTESTA------------------TSITLTW----DSGNPEPVSYYIIQHKPKNSE 337
Query: 371 VEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQV 430
L K+ + T ++ Y+ Y+ +V A N+IG GP SE V ++E P
Sbjct: 338 E-----LYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSS 392
Query: 431 APQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRN 490
AP+ V AR +ST + V W + E G++ G+R+ Y + +
Sbjct: 393 APRDVQARMLSSTTILVQW----KEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQ 448
Query: 491 WALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRV 550
I L P Y VKV+AF S G+GP S T P +P +N A + +
Sbjct: 449 ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP---LNFKAEPESETSI 505
Query: 551 VWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVL 610
+ + P + + Y++ + +D + + IE + + P Y R+
Sbjct: 506 LLSWTPP--RSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLA 559
Query: 611 AYSNGGDG 618
A S G G
Sbjct: 560 ARSPQGLG 567
Score = 74.9 bits (176), Expect = 8e-13
Identities = 53/181 (29%), Positives = 91/181 (50%), Gaps = 11/181 (6%)
Query: 442 STALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+T++ +TW+ + E + +I H+ K ++ KE + + TTR + GL P +
Sbjct: 309 ATSITLTWD--SGNPEPVSYYIIQHKPKNSEELYKEIDGV----ATTRY--SVAGLSPYS 360
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE 561
Y +V+A N+ G GP SE L +T +AP P V TT+ V W+ +P
Sbjct: 361 DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPN 418
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
+ GY+V + +D N + I N++P K+Y+++VLA+++ GDG +S
Sbjct: 419 GQIQGYRV-YYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLS 477
Query: 622 S 622
S
Sbjct: 478 S 478
Score = 55.2 bits (127), Expect = 7e-07
Identities = 86/361 (23%), Positives = 138/361 (38%), Gaps = 42/361 (11%)
Query: 2 YQCEAKNQLKASYSS-AQLRVLSLK------PSFKKHPLELETYGSEGGNVTLKCKPEAA 54
Y+C A N YS+ A L V L+ P F P E GG+V + C +
Sbjct: 178 YECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGS 235
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
P P W + I N ++ YTCVA + G E+ ++ V
Sbjct: 236 PMPYVKWMLGAEDLTPEDDMPIGRN---VLELNDVRQSANYTCVAMSTLGVIEAIAQITV 292
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P+ P + S+ + + +P+ + Y+ H + K+S +LY +
Sbjct: 293 KALPK-PPGTPVVTESTATSITLTWDSGNPEPV--SYYIIQH---KPKNSEELYK----E 342
Query: 175 IDGGELTIYNVS-LSDVGDYE--CVVKSAIGR--ISSHV--QLRIEGPPGPPGGVQILGI 227
IDG T Y+V+ LS DYE V + IGR S V Q + P P VQ +
Sbjct: 343 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 402
Query: 228 QRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVS 286
+++ ++W + I GY + Y + +V ++N + T
Sbjct: 403 SSTTILVQWKEPEEPNGQIQGYRV----------YYTMDPTQHVNNWMKHNVADSQITTI 452
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L+P Y ++ A +G G P + Q T P + P N + ++WT
Sbjct: 453 GNLVPQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPGQ-PLNFKAEPESETSILLSWT 510
Query: 347 P 347
P
Sbjct: 511 P 511
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 107 bits (258), Expect = 1e-22
Identities = 131/549 (23%), Positives = 222/549 (40%), Gaps = 79/549 (14%)
Query: 45 VTLKCKPEAAPKPTFTWKKD---NIVIG----AGGKRF-ITENGNLIIRQLSRDDEGVYT 96
VT +C+ P+P W+++ N++ RF +++ G+L I + R D G Y
Sbjct: 3 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 62
Query: 97 CVAKNQYGTDESRGRLIVL-----RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTA 151
C N G+ ++ L V R P + + P T V+ L C A P+
Sbjct: 63 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PT 120
Query: 152 YLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQL 210
LW +G+ + + RIK ++ G L I L D G Y C+ + G + +
Sbjct: 121 ILWRKDGVLVSTQ-----DSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYI 175
Query: 211 RIEG----------PPGP---------PGGVQILGIQRSSVTLEWTDSNSNGRPITGYML 251
++G PP P P ++ + R++VTL W + ++G T Y++
Sbjct: 176 EVQGKVNEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYII 235
Query: 252 TGRTHWN-STWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQP 310
+H + S+W ++EN+ E G K P AIY F ++A N G P
Sbjct: 236 EAFSHASGSSWQTVAENVKT--ETSAIKGLK---------PNAIYLFLVRAANAYGISDP 284
Query: 311 SAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGP-GIH---------- 359
S S T P + + G+ + PT L + +H
Sbjct: 285 SQISDPVKTQDVLPTSQGVDHKQVQRELGN-AVLHLHNPTVLSSSSIEVHWTVDQQSQYI 343
Query: 360 --YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESE 417
YKI +R +G+ L+ + V I Y++K + F + G +SE
Sbjct: 344 QGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSE 403
Query: 418 VVTIYSAEDMPQVAPQ--LVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
+ + E+ P PQ VS N TA+ V+W P + + G + K W N
Sbjct: 404 IKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQ--NGMV--QEYKVWCLGN 459
Query: 476 KEEECIYYLSRTT--RNWALIVG-LQPDTYYYVKVMAFNSAGEGPESE-RYLERTFRKAP 531
E Y++++T +++++ L P Y V+V A AG G +SE ++++ P
Sbjct: 460 ---ETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNP 516
Query: 532 QKPPASVNV 540
P V++
Sbjct: 517 VSPEDQVSL 525
Score = 59.3 bits (137), Expect = 4e-08
Identities = 101/471 (21%), Positives = 179/471 (38%), Gaps = 36/471 (7%)
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG--PPGPPGGVQILGIQRSSVTLE 235
G+LTI NV SDVG Y C + G I + L + PP ++ G +V ++
Sbjct: 46 GDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVD 104
Query: 236 WT---DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY-----NGRKRATVST 287
T + G P+ + ST + + N + RY GR ST
Sbjct: 105 GTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIAST 164
Query: 288 TL--LPWAIYEFRIQA-INILG-PGQPSAPS-PQFSTSGDKPYEAPANVSGGGGKTGDLT 342
W+ Y +Q +N G P QP P+ P S AP+ +T
Sbjct: 165 PSGEATWSAY-IEVQGKVNEFGVPVQPPRPTDPNLIPS------APSKPEVTDVSRNTVT 217
Query: 343 ITWTP------LPTSLQNGPGIHYK-IFWRRNGSEVEFQSLLLK--KYGNIGTYVVHISS 393
++W P PTS H W+ V+ ++ +K K I ++V ++
Sbjct: 218 LSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAAN 277
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAE-DMPQVAPQLVSARSFNSTALNVTWNPI 452
Y + P S+ V + ++ L + +S+++ V W +
Sbjct: 278 AYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT-V 336
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
DQ + ++G I +R + + ++ + +N +I L+ Y +K F +
Sbjct: 337 DQQSQYIQGYKILYRPS-GANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFN 395
Query: 513 AGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLW 572
+G +SE +T +AP PP V V +D ++ + P + + + + ++W
Sbjct: 396 EFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVW 455
Query: 573 ELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSP 623
L + + V I ++PG Y++ V A + G G S P
Sbjct: 456 CLGNETRYHINKTVD-GSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEP 505
Score = 48.0 bits (109), Expect = 1e-04
Identities = 33/109 (30%), Positives = 48/109 (44%), Gaps = 8/109 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-----KPSFKKHPLELETYGSEGGNVTLKCKPEAAPK 56
Y C+ N + + A L V + P ++ P+ +T +G V L C +P
Sbjct: 61 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVN-QTVAVDGTFV-LSCVATGSPV 118
Query: 57 PTFTWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYG 104
PT W+KD +++ R ENG L IR D G YTC+A G
Sbjct: 119 PTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 167
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 106 bits (255), Expect = 2e-22
Identities = 134/543 (24%), Positives = 223/543 (41%), Gaps = 53/543 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQY 103
V L+C PKP +W + D+ I R + NGNL+I + GVY C A
Sbjct: 252 VVLECMATGNPKPIISWSRLDHKSIDVFNTR-VLGNGNLMISDVRLQHAGVYVCRATTP- 309
Query: 104 GTDE---SRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
GT + L VL P F+E P +T C A+ P W NG +
Sbjct: 310 GTRNFTVAMATLTVLAPPSFVE-WPESLTRPRAGTARFVCQAEGIP--SPKMSWLKNGRK 366
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---EGPPG 217
I + N RIK+ +L I + D Y+C+ +++ G I S +L + E P
Sbjct: 367 I------HSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPS 420
Query: 218 PPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY 277
P V + S++ L W N + Y S Y+ +E + N
Sbjct: 421 APYNVHAETMSSSAILLAWERPLYNSDKVIAY---------SVHYMKAEGLNNEEYQVVI 471
Query: 278 NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGK 337
+ L P + Y F I A +G Q S Q +T D P P +S
Sbjct: 472 GNDTTHYIIDDLEPASNYTFYIVAYMPMGASQMSDHVTQ-NTLEDVPLR-PPEISLTSRS 529
Query: 338 TGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY 397
D+ I+W P+P + G + Y++ +R + +E Q L L G Y+ +
Sbjct: 530 PTDILISWLPIPAKYRRGQVVLYRLSFRLS-TENSIQVLELP--GTTHEYL--LEGLKPD 584
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQV-APQL--VSARSFNSTALNVTWNPIDQ 454
+ Y V++ A +G G ES V T + V AP+ + N T ++V W +
Sbjct: 585 SVYLVRITAATRVGLG-ESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWQQDVE 643
Query: 455 SRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAG 514
++ G++L Y+K+E ++E +L + L GL P Y+V+++A+N+
Sbjct: 644 DTAAIQ----GYKL-YYKEEGQQENGPIFLDTKDLLYTL-SGLDPRRKYHVRLLAYNNID 697
Query: 515 EGPESERYLE-------RTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGY 567
+G ++++ + R P PP + A+ +++ + WR +P ++ Y
Sbjct: 698 DGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWR--RPAFTAAQIINY 755
Query: 568 KVR 570
+R
Sbjct: 756 TIR 758
Score = 103 bits (246), Expect = 3e-21
Identities = 157/640 (24%), Positives = 249/640 (38%), Gaps = 58/640 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC A N+ A S LS +F+ P+ E + EGG CK + P TW
Sbjct: 111 YQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVH--EGGVARFACKISSHPPAVITW 168
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDES-RGRLIVLRA-- 117
+ + + R G L I +S+ D G Y C+A +S L V+ A
Sbjct: 169 EFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSMEASLTVIPAKE 228
Query: 118 ------PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNK 171
P + P IT ++ V L C A +P W+ R+ S N
Sbjct: 229 SKSFHTPTIIAG-PQNITTSLHQTVVLECMATGNP--KPIISWS----RLDHKSIDVFNT 281
Query: 172 RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS 231
R+ + G L I +V L G Y C + G + V + PP V
Sbjct: 282 RV-LGNGNLMISDVRLQHAGVYVCRATTP-GTRNFTVAMATLTVLAPPSFV--------- 330
Query: 232 VTLEWTDSNSNGRPITGYMLT---GRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
EW +S + R T + G +W I + + YN + V
Sbjct: 331 ---EWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYNSK---LVINQ 384
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT-P 347
++P ++ A N G S S D+P AP NV + + + W P
Sbjct: 385 IIPEDDAIYQCMAENSQG-SILSRARLTVVMSEDRP-SAPYNVHAETMSSSAILLAWERP 442
Query: 348 LPTSLQN-GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
L S + +HY N E +Q ++ GN T+ + I + Y + A
Sbjct: 443 LYNSDKVIAYSVHYMKAEGLNNEE--YQVVI----GNDTTHYI-IDDLEPASNYTFYIVA 495
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
+ +G S+ VT + ED+P P+ +S S + T + ++W PI R G+++ +
Sbjct: 496 YMPMGASQMSDHVTQNTLEDVPLRPPE-ISLTSRSPTDILISWLPIPAKYRR--GQVVLY 552
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
RL + + + + L TT + L+ GL+PD+ Y V++ A G G S RT
Sbjct: 553 RLSF-RLSTENSIQVLELPGTTHEY-LLEGLKPDSVYLVRITAATRVGLGESSVWTSHRT 610
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIV 586
+ K P S + + R+ Q + + GYK+ E Q N I
Sbjct: 611 PKATSVKAPKSPELHLEPLNCTTISVRWQQDVEDTAAIQGYKLYYKEEGQQ---ENGPIF 667
Query: 587 PIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
L +S + P + Y++R+LAY+N DG + T++
Sbjct: 668 LDTKDLLYTLSGLDPRRKYHVRLLAYNNIDDGYQADQTVS 707
Score = 76.6 bits (180), Expect = 3e-13
Identities = 133/645 (20%), Positives = 259/645 (40%), Gaps = 60/645 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP-SFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y C A +++ A + L P SF + P L G C+ E P P
Sbjct: 301 VYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTR--PRAGTARFVCQAEGIPSPKM 358
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+W K+ I + G R N L+I Q+ +D+ +Y C+A+N G+ SR RL V+ +
Sbjct: 359 SWLKNGRKIHSNG-RIKMYNSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMS-E 416
Query: 120 FLEKLPPRITAQV--NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P + A+ +S + L A P+ ++ + ++ + + L + + G
Sbjct: 417 DRPSAPYNVHAETMSSSAILL---AWERPLYNSDKVIAYS-VHYMKAEGLNNEEYQVVIG 472
Query: 178 GELTIYNV-SLSDVGDYECVVKS----AIGRISSHV-QLRIEGPPGPPGGVQILGIQRSS 231
+ T Y + L +Y + + ++S HV Q +E P P + + +
Sbjct: 473 NDTTHYIIDDLEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTD 532
Query: 232 VTLEWTDSNSNGRPITGYMLTGR-THWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
+ + W PI G+ + ++ + +EN V+E+ G + L
Sbjct: 533 ILISWL-------PIPAKYRRGQVVLYRLSFRLSTENSIQVLELP---GTTHEYLLEGLK 582
Query: 291 PWAIYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
P ++Y RI A +G G+ S +P+ +TS P ++ T +++ W
Sbjct: 583 PDSVYLVRITAATRVGLGESSVWTSHRTPK-ATSVKAPKSPELHLEPLNCTT--ISVRW- 638
Query: 347 PLPTSLQNGPGIH-YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQ 405
+++ I YK++++ G + L K + +S Y V++
Sbjct: 639 --QQDVEDTAAIQGYKLYYKEEGQQENGPIFLDTK-----DLLYTLSGLDPRRKYHVRLL 691
Query: 406 AFNDIGPGPESE-------VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
A+N+I G +++ V++ P P + A++ S+++ + W +
Sbjct: 692 AYNNIDDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHW----RRPAF 747
Query: 459 LRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE 518
++I + ++ + + YL +T+ L+ GL+P+T Y V P
Sbjct: 748 TAAQIINYTIRCNPVGLQNASLVLYL-QTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPW 806
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S T +AP PP V V + T V W+ P E + Y + L+ +
Sbjct: 807 SPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWK--PPDGPETVVTRYTI-LYASRKAW 863
Query: 579 STANDTIVPIEHKLE-AYISNIIPGKSYNLRVLAYSNGGDGRMSS 622
++ E + A + N++ G Y +++ A + G+G S+
Sbjct: 864 IAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSN 908
Score = 53.2 bits (122), Expect = 3e-06
Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 27 SFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQ 86
SF K P ++ + V L C+ TW K+ + + + NG+L I +
Sbjct: 40 SFVKEPQDVTVTRKDP--VVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISE 97
Query: 87 LS-----RDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
+ + DEG Y C+A N+YG S+ + L E P V C
Sbjct: 98 VEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACK 157
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI 201
P W N + + + +++ + G L IY+VS D G+Y C+ +
Sbjct: 158 ISSHP--PAVITWEFN----RTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVA 211
Query: 202 GRISS 206
R S
Sbjct: 212 HRRKS 216
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 106 bits (255), Expect = 2e-22
Identities = 141/566 (24%), Positives = 226/566 (39%), Gaps = 74/566 (13%)
Query: 42 GGNVTLKCKPEAAPKPTFTW-KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAK 100
G +V ++C A P P +W ++D I + NL+I GVY C A
Sbjct: 258 GQSVVMECVASADPTPFVSWVRQDGKPISTDV--IVLGRTNLLIANAQPWHSGVYVCRAN 315
Query: 101 NQYGTD--ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
D + L VL AP + + P ++ S C A +P A W HNG
Sbjct: 316 KPRTRDFATAAAELRVLAAPA-ITQAPEALSRTRASTARFVCRASGEP--RPALRWLHNG 372
Query: 159 LRIKDSSDLYVNKRIKIDGG--ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---E 213
++ N R+K+ GG L I + L D G Y+CV +++ G + L + E
Sbjct: 373 APLRP------NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVRE 426
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
G P P V + S+V + W + I G+ L H+ + + NV
Sbjct: 427 GLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSL----HYQK-----ARGMDNVEY 477
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
N L P YEF + A + LG + S P+ T D P AP +S
Sbjct: 478 QFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPA-LVHTLDDVPSAAP-QLSL 535
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISS 393
D+ + W PLP SL NG + YKI + G E Q + GN T ++ ++S
Sbjct: 536 SSPNPSDIRVAWLPLPPSLSNGQVVKYKIEY---GLGKEDQIFSTEVRGN-ETQLM-LNS 590
Query: 394 TYFYTPYDVKVQAFNDIGPGPESE-----VVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
Y V++ A G G S+ ++++ +P AP + ++ +L V+
Sbjct: 591 LQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVP-FAPAELKVQA-KMESLVVS 648
Query: 449 WNPIDQSRERLRGKLIGHRLKYWKQENKEEEC---IYYLSRTTRNWAL------------ 493
W P + + G++L YW++ EEE R + W +
Sbjct: 649 WQPPPHPTQ-----ISGYKL-YWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQY 702
Query: 494 -IVGLQPDTYYYVKVMAFNSAGEG--------PESERYLERTFRKAPQKPPASVNVWAHD 544
+ L P Y VK++AFN +G E + ++ P PPA V+ ++
Sbjct: 703 ELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNS 762
Query: 545 PTTLRVVWRYVQPTNEEEPLLGYKVR 570
T++ + W+ +P ++ Y VR
Sbjct: 763 STSIWLRWK--KPDFTTVKIVNYTVR 786
Score = 98.7 bits (235), Expect = 6e-20
Identities = 157/649 (24%), Positives = 255/649 (39%), Gaps = 73/649 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A L S + L+ F HP E +T E G +C E P P TW
Sbjct: 119 YSCLAHGPLGVLASQTAVVKLATLADFSLHP-ESQTV-EENGTARFECHIEGLPAPIITW 176
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN---QYGTDES------RGRL 112
+KD + + + + NG L I + D G Y CVA N Q+ + E+ RG L
Sbjct: 177 EKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSL 236
Query: 113 IVLRAPRFLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNK 171
R + P T V+ V + C A DP +++ +G I S+D+ V
Sbjct: 237 ASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWV-RQDGKPI--STDVIVLG 293
Query: 172 RIKIDGGELTIYNVSLSDVGDYECVVKSAIGR--ISSHVQLRIEGPPGPPGGVQILGIQR 229
R L I N G Y C R ++ +LR+ P + L R
Sbjct: 294 RTN-----LLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAITQAPEALSRTR 348
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+S ++ RP ++ G + PN V G ++
Sbjct: 349 ASTARFVCRASGEPRPALRWLHNG-----------APLRPNG-RVKVQGGGGSLVITQIG 396
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT-PL 348
L A Y ++ A N G +A G P AP V+ + + + W P
Sbjct: 397 LQDAGY-YQCVAENSAGMACAAASLAVVVREG-LP-SAPTRVTATPLSSSAVLVAWERPE 453
Query: 349 PTSLQN-GPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
S Q G +HY+ R VE+Q + N T + + T Y+ V A+
Sbjct: 454 MHSEQIIGFSLHYQK--ARGMDNVEYQFAV-----NNDTTELQVRDLEPNTDYEFYVVAY 506
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
+ +G S +++ +D+P APQL S S N + + V W P+ S G+++ ++
Sbjct: 507 SQLGASRTSTPALVHTLDDVPSAAPQL-SLSSPNPSDIRVAWLPLPPSLSN--GQVVKYK 563
Query: 468 LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
++Y KE++ R ++ LQP+ Y V++ A +AG G S+ RT
Sbjct: 564 IEYGL--GKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTP 621
Query: 528 RKAPQK----PPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
Q PA + V A +L V W QP + GYK+ E+ + D
Sbjct: 622 SMHNQSHVPFAPAELKVQA-KMESLVVSW---QPPPHPTQISGYKLYWREVGAEEEANGD 677
Query: 584 TI-------------VPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
+ V ++ K++ Y ++ ++PG+ Y ++++A++ DG
Sbjct: 678 RLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDG 726
Score = 74.1 bits (174), Expect = 1e-12
Identities = 132/600 (22%), Positives = 228/600 (38%), Gaps = 56/600 (9%)
Query: 1 MYQCEAKNQLKASYSSA--QLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y C A +++A +LRVL+ P+ + P L + C+ P+P
Sbjct: 309 VYVCRANKPRTRDFATAAAELRVLAA-PAITQAPEALSR--TRASTARFVCRASGEPRPA 365
Query: 59 FTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W + + G+ + G +L+I Q+ D G Y CVA+N G + L V+
Sbjct: 366 LRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVV-V 424
Query: 118 PRFLEKLPPRITAQ-VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
L P R+TA ++S L + + ++ + + + ++ + D
Sbjct: 425 REGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNVEYQFAVNND 484
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIG--RISSHVQLR-IEGPPGPPGGVQILGIQRSSVT 233
EL + ++ + ++ V S +G R S+ + ++ P + + S +
Sbjct: 485 TTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLSLSSPNPSDIR 544
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWA 293
+ W P+ + G+ Y + + + + G + + +L P
Sbjct: 545 VAWL-------PLPPSLSNGQVVKYKIEYGLGKE-DQIFSTE-VRGNETQLMLNSLQPNK 595
Query: 294 IYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLP 349
+Y RI A G G PS +P P+ APA + K L ++W P P
Sbjct: 596 VYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPF-APAELKVQA-KMESLVVSWQPPP 653
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLK-----KYGNIGTYVVHIS-STYFYTP---- 399
Q YK++WR G+E E L + ++G + Y T
Sbjct: 654 HPTQISG---YKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPG 710
Query: 400 --YDVKVQAFNDIGPGPESE---VVTIYSAEDMP-QVAPQL----VSARSFNSTALNVTW 449
Y+VK+ AFN G + A DMP Q P L V A S +ST++ + W
Sbjct: 711 RLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIWLRW 770
Query: 450 NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMA 509
D + ++ + R W N YY S + LI GL+P T Y V +
Sbjct: 771 KKPDFTTVKIVNYTV--RFSPWGLRNASL-VTYYTS--SGEDILIGGLKPFTKYEFAVQS 825
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
+GP T P PP+ + + P+T+R+ W PT ++ Y +
Sbjct: 826 HGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHW--CPPTEPNGEIVEYLI 883
Score = 58.8 bits (136), Expect = 6e-08
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 15/213 (7%)
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
GPP PP V +S+ L W + I Y + S W + N
Sbjct: 748 GPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRF-----SPW-----GLRNASL 797
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
V Y + L P+ YEF +Q+ + G P + ST D+P P+++
Sbjct: 798 VTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDG-PFGSVVERSTLPDRPSTPPSDLRL 856
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISS 393
+ + W P PT NG + Y I + N ++ E Q LL GNI + VH
Sbjct: 857 SPLTPSTVRLHWCP-PTE-PNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVH--G 912
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED 426
T Y K+ A ++GPGP S + + + ++
Sbjct: 913 LESDTRYFFKMGARTEVGPGPFSRLQDVITLQE 945
Score = 40.7 bits (91), Expect = 0.016
Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 6/142 (4%)
Query: 495 VGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRY 554
+GLQ YY + +A NSAG + L R+ P V + + V W
Sbjct: 395 IGLQDAGYY--QCVAENSAGMACAAAS-LAVVVREGLPSAPTRVTATPLSSSAVLVAWE- 450
Query: 555 VQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSN 614
+P E ++G+ + ++ + M E + ++ P Y V+AYS
Sbjct: 451 -RPEMHSEQIIGFSLH-YQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQ 508
Query: 615 GGDGRMSSPTIAFQIGDYHSEA 636
G R S+P + + D S A
Sbjct: 509 LGASRTSTPALVHTLDDVPSAA 530
Score = 39.9 bits (89), Expect = 0.029
Identities = 55/244 (22%), Positives = 98/244 (40%), Gaps = 24/244 (9%)
Query: 287 TTLLPWAIYEFRIQAINILGPGQPS--------APSPQFSTSGDKPYEAPANVSGGGGKT 338
T L+P +YE ++ A N G + AP+P P PA+V +
Sbjct: 705 TQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLP-PAHVHAESNSS 763
Query: 339 GDLTITWT-PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY 397
+ + W P T+++ ++Y + + G + L+ Y + G ++ I +
Sbjct: 764 TSIWLRWKKPDFTTVKI---VNYTVRFSPWGLR---NASLVTYYTSSGEDIL-IGGLKPF 816
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
T Y+ VQ+ GP VV + D P P + + + + W P +
Sbjct: 817 TKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPN- 875
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNW--ALIVGLQPDTYYYVKVMAFNSAGE 515
G+++ + + Y + + E + L T N A + GL+ DT Y+ K+ A G
Sbjct: 876 ---GEIVEYLILY-SSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGP 931
Query: 516 GPES 519
GP S
Sbjct: 932 GPFS 935
Score = 33.5 bits (73), Expect = 2.5
Identities = 37/161 (22%), Positives = 58/161 (36%), Gaps = 20/161 (12%)
Query: 53 AAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQL----SRDD---------EGVYTCVA 99
A P TW KD + + NG+L + Q D+ EG Y+C+A
Sbjct: 64 AGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLA 123
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
G S+ ++ L P T + N C+ + P W + +
Sbjct: 124 HGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPA--PIITWEKDQV 181
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSA 200
+ + L V + G L I +V SD G Y CV ++
Sbjct: 182 TLPEEPRLIV-----LPNGVLQILDVQESDAGPYRCVATNS 217
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 106 bits (254), Expect = 3e-22
Identities = 135/534 (25%), Positives = 219/534 (41%), Gaps = 54/534 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITEN---GN 81
KP F K P E +T G GG + C+ PKP TW K + + I + G+
Sbjct: 52 KPVFIKVP-EDQT-GLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGS 109
Query: 82 LIIRQLSR--DDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPP-------RITAQV 132
++ Q R DE +Y C A N G + +L VL + P ++ +
Sbjct: 110 VLRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 169
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ L C A +P D W + L + ++ N RIK + G L I + SD G
Sbjct: 170 RTATML-CAAGGNP--DPEISWFKDFLPVDPATS---NGRIKQLRSGALQIESSEESDQG 223
Query: 192 DYECVVKSAIG-RISSHVQL---------RIEGPPGPPGGVQIL-GIQRSSVTLEWTDSN 240
YECV ++ G R S+ L R PP P V+ G+ + +
Sbjct: 224 KYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSPTIQVKTQQGVPAQPADFQ-AEVE 282
Query: 241 SNGRPITGYMLTG--RTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
S+ R ++L R Y +E+ +V ++ T+ L P +Y F+
Sbjct: 283 SDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVT-FDPTSSYTLED-LKPDTLYRFQ 340
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGI 358
+ A + +G G P+ + T+ P P V + + ++W P P +NG
Sbjct: 341 LAARSDMGVGV-FTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVIT 399
Query: 359 HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEV 418
Y + + E + ++ ++ + +T Y V V+A D+GPGPES
Sbjct: 400 QYSVAYEAVDGEDRGRHVVDGISREHSSW--DLVGLEKWTEYRVWVRAHTDVGPGPESSP 457
Query: 419 VTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEE 478
V + + ED+P P+ V NSTA++V W S++ G++ G+++ Y + EN E
Sbjct: 458 VLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQ--HGQIRGYQVTYVRLENGEP 515
Query: 479 E---CIYYLSRTTRNW---------ALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
I + W I GL P+T Y V V A+ + G+G S+
Sbjct: 516 RGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSK 569
Score = 96.3 bits (229), Expect = 3e-19
Identities = 76/262 (29%), Positives = 114/262 (43%), Gaps = 16/262 (6%)
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
T Y ++ A +D+G G + + +A+ P PQ V S ST + V+W P +
Sbjct: 335 TLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP--PPAD 392
Query: 458 RLRGKLIGHRLKYWKQ--ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
G + + + Y E++ + +SR +W L VGL+ T Y V V A G
Sbjct: 393 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDL-VGLEKWTEYRVWVRAHTDVGP 451
Query: 516 GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELD 575
GPES L RT P PP V V + T + V W+ P+ + + GY+V L+
Sbjct: 452 GPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLE 511
Query: 576 ----------QDMSTANDTIVPIEHK-LEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
QD+ A P E + E IS + P +Y++ V AY+ GDG S P
Sbjct: 512 NGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPK 571
Query: 625 IAFQIGDYHSEAYGYYARGSTS 646
I G ++ + A TS
Sbjct: 572 IVTTTGAVFAKNFRVAAAMKTS 593
Score = 53.2 bits (122), Expect = 3e-06
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 13/145 (8%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A N L +SA+L VL L P F + + E T+ C P
Sbjct: 124 IYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPD 183
Query: 57 PTFTWKKDNIVIG---AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P +W KD + + + G+ +G L I D+G Y CVA N GT S +
Sbjct: 184 PEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANL 243
Query: 114 VLR----APRFLEKLPPRITAQVNS 134
+R APRF +PP T QV +
Sbjct: 244 YVRVRRVAPRF--SIPPSPTIQVKT 266
Score = 48.4 bits (110), Expect = 8e-05
Identities = 72/330 (21%), Positives = 131/330 (39%), Gaps = 29/330 (8%)
Query: 305 LGPGQPSAP-SPQFSTSGDKPYEAPANVSGGGGKTGDLTITW----TPLPTSLQNGPGIH 359
L PG PS PQ +K A + GG D I+W P+ + NG
Sbjct: 150 LPPGFPSIDMGPQLKVV-EKARTATMLCAAGGNP--DPEISWFKDFLPVDPATSNG---- 202
Query: 360 YKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPG---PES 416
+I R+G+ ++ +S G + + T + P ++ V+ + P P S
Sbjct: 203 -RIKQLRSGA-LQIESSEESDQGKYECVATNSAGTRYSAPANLYVRV-RRVAPRFSIPPS 259
Query: 417 EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENK 476
+ + + + +P P A + T + ++W Q R +I + L YW E++
Sbjct: 260 PTIQVKTQQGVP-AQPADFQAEVESDTRIQLSWLLPPQER------IIMYELVYWAAEDE 312
Query: 477 EEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
+++ T+ + L+PDT Y ++ A + G G + RT + P PP
Sbjct: 313 DQQHKVTFDPTSSY--TLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQ 370
Query: 537 SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY- 595
V + TT+RV W + + Y V +D + + I + ++
Sbjct: 371 KVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGE-DRGRHVVDGISREHSSWD 429
Query: 596 ISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
+ + Y + V A+++ G G SSP +
Sbjct: 430 LVGLEKWTEYRVWVRAHTDVGPGPESSPVL 459
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 105 bits (253), Expect = 4e-22
Identities = 140/591 (23%), Positives = 242/591 (40%), Gaps = 61/591 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL---SLKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A+N + A+L VL L F + + E T+ C P
Sbjct: 104 VYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPD 163
Query: 57 PTFTWKKDNIVI---GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P TW KD + + + G+ +G L I D+G Y CVA N G S +
Sbjct: 164 PEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANL 223
Query: 114 VLR----APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
+R APRF LP V + C A P+ ++ L +D D+ V
Sbjct: 224 YVRVRRVAPRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED--DMPV 280
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQR 229
+ + ELT + D +Y CV S++G I + Q+ ++ P PG +
Sbjct: 281 GRNVL----ELT----DVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTA 332
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+S+T+ W N + P++ Y++ ++ Y I E+I RY+ L
Sbjct: 333 TSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS-------IGGL 379
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW-TPL 348
P + YE + A+N +G G PS S T P AP NV + + W P+
Sbjct: 380 SPNSEYEIWVSAVNSIGQGPPS-ESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPV 438
Query: 349 -PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
P L G ++Y + E E +K+ + + + S Y V+V AF
Sbjct: 439 EPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAF 491
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
+G GP S+ + + + + +P P + A + + T++ ++W+P Q +I +
Sbjct: 492 TSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE------SIIKYE 544
Query: 468 LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
L + + ++ E + T+ ++ L+P+T Y ++ A + G G + +RT
Sbjct: 545 LLFREGDHGREVGRTFDPTTS---YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTL 601
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
+ P + V T++ + W + P N P YK++ L D+
Sbjct: 602 QSI---SPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 646
Score = 72.1 bits (169), Expect = 6e-12
Identities = 54/207 (26%), Positives = 101/207 (48%), Gaps = 12/207 (5%)
Query: 417 EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENK 476
E V + + +P+ AP +T++ +TW+ + + + +I ++ K +
Sbjct: 308 EAVAQITVKSLPK-APGTPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGPYQ 364
Query: 477 EEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
+E I TT ++ I GL P++ Y + V A NS G+GP SE + RT +AP P
Sbjct: 365 IKEDI-----TTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPR 418
Query: 537 SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYI 596
+V TT+ V W +P + GY+V + ++ + N ++ L +
Sbjct: 419 NVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTV 475
Query: 597 SNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+++ ++Y +RVLA+++ GDG +S P
Sbjct: 476 GSLLEDETYTVRVLAFTSVGDGPLSDP 502
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/280 (26%), Positives = 123/280 (43%), Gaps = 26/280 (9%)
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+TITW S P +Y I ++ + +Q +K+ +I T I + Y
Sbjct: 335 ITITWD----SGNPDPVSYYVIEYKSKSQDGPYQ---IKE--DITTTRYSIGGLSPNSEY 385
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERL 459
++ V A N IG GP SE V + E P AP+ V AR ++T + V W P++ +
Sbjct: 386 EIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPN---- 441
Query: 460 RGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGPE 518
G + G+R+ Y+ E + + + VG L D Y V+V+AF S G+GP
Sbjct: 442 -GLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 499
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S+ +T + P + P ++ A T++ + W P +E ++ Y++ E D
Sbjct: 500 SDPIQVKTQQGVPGQ-PMNLRAEARSETSITLSW---SPPRQES-IIKYELLFREGDHGR 554
Query: 579 STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
T P + + ++ P Y R+ A S G G
Sbjct: 555 EVGR-TFDPTTSYV---VEDLKPNTEYAFRLAARSPQGLG 590
Score = 59.3 bits (137), Expect = 4e-08
Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 24/202 (11%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT----ENGN 81
P F K P + G GG + C+ PKP TW K + + +RF T E+
Sbjct: 33 PRFIKEPKD--QIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNS--QRFETIEFDESAG 88
Query: 82 LIIR-QLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
++R Q R DE VY CVA+N G +L VLR + P P++ +
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ C A +P D W + L + S+ N RIK + G L I + +D G
Sbjct: 149 TRTATMLCAASGNP--DPEITWFKDFLPVDPSAS---NGRIKQLRSGALQIESSEETDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R SS L +
Sbjct: 204 KYECVATNSAGVRYSSPANLYV 225
Score = 31.9 bits (69), Expect = 7.6
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PRF+++ +I F+ C A DP WN G ++ +S + + G
Sbjct: 33 PRFIKEPKDQIGVSGGVASFV-CQATGDP--KPRVTWNKKGKKV-NSQRFETIEFDESAG 88
Query: 178 GELTIYNVSLS-DVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L I + D YECV ++++G I+ H +L + P G
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 105 bits (253), Expect = 4e-22
Identities = 140/591 (23%), Positives = 242/591 (40%), Gaps = 61/591 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL---SLKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A+N + A+L VL L F + + E T+ C P
Sbjct: 130 VYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPD 189
Query: 57 PTFTWKKDNIVI---GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P TW KD + + + G+ +G L I D+G Y CVA N G S +
Sbjct: 190 PEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANL 249
Query: 114 VLR----APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
+R APRF LP V + C A P+ ++ L +D D+ V
Sbjct: 250 YVRVRRVAPRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED--DMPV 306
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQR 229
+ + ELT + D +Y CV S++G I + Q+ ++ P PG +
Sbjct: 307 GRNVL----ELT----DVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENTA 358
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+S+T+ W N + P++ Y++ ++ Y I E+I RY+ L
Sbjct: 359 TSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS-------IGGL 405
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW-TPL 348
P + YE + A+N +G G PS S T P AP NV + + W P+
Sbjct: 406 SPNSEYEIWVSAVNSIGQGPPS-ESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPV 464
Query: 349 -PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAF 407
P L G ++Y + E E +K+ + + + S Y V+V AF
Sbjct: 465 EPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAF 517
Query: 408 NDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHR 467
+G GP S+ + + + + +P P + A + + T++ ++W+P Q +I +
Sbjct: 518 TSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE------SIIKYE 570
Query: 468 LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTF 527
L + + ++ E + T+ ++ L+P+T Y ++ A + G G + +RT
Sbjct: 571 LLFREGDHGREVGRTFDPTTS---YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTL 627
Query: 528 RKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
+ P + V T++ + W + P N P YK++ L D+
Sbjct: 628 QSI---SPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 672
Score = 72.1 bits (169), Expect = 6e-12
Identities = 54/207 (26%), Positives = 101/207 (48%), Gaps = 12/207 (5%)
Query: 417 EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENK 476
E V + + +P+ AP +T++ +TW+ + + + +I ++ K +
Sbjct: 334 EAVAQITVKSLPK-APGTPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGPYQ 390
Query: 477 EEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
+E I TT ++ I GL P++ Y + V A NS G+GP SE + RT +AP P
Sbjct: 391 IKEDI-----TTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPR 444
Query: 537 SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYI 596
+V TT+ V W +P + GY+V + ++ + N ++ L +
Sbjct: 445 NVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTV 501
Query: 597 SNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+++ ++Y +RVLA+++ GDG +S P
Sbjct: 502 GSLLEDETYTVRVLAFTSVGDGPLSDP 528
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/280 (26%), Positives = 123/280 (43%), Gaps = 26/280 (9%)
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+TITW S P +Y I ++ + +Q +K+ +I T I + Y
Sbjct: 361 ITITWD----SGNPDPVSYYVIEYKSKSQDGPYQ---IKE--DITTTRYSIGGLSPNSEY 411
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERL 459
++ V A N IG GP SE V + E P AP+ V AR ++T + V W P++ +
Sbjct: 412 EIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPN---- 467
Query: 460 RGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGPE 518
G + G+R+ Y+ E + + + VG L D Y V+V+AF S G+GP
Sbjct: 468 -GLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 525
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S+ +T + P + P ++ A T++ + W P +E ++ Y++ E D
Sbjct: 526 SDPIQVKTQQGVPGQ-PMNLRAEARSETSITLSW---SPPRQES-IIKYELLFREGDHGR 580
Query: 579 STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
T P + + ++ P Y R+ A S G G
Sbjct: 581 EVGR-TFDPTTSYV---VEDLKPNTEYAFRLAARSPQGLG 616
Score = 59.3 bits (137), Expect = 4e-08
Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 24/202 (11%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT----ENGN 81
P F K P + G GG + C+ PKP TW K + + +RF T E+
Sbjct: 59 PRFIKEPKD--QIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNS--QRFETIEFDESAG 114
Query: 82 LIIR-QLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
++R Q R DE VY CVA+N G +L VLR + P P++ +
Sbjct: 115 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 174
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ C A +P D W + L + S+ N RIK + G L I + +D G
Sbjct: 175 TRTATMLCAASGNP--DPEITWFKDFLPVDPSAS---NGRIKQLRSGALQIESSEETDQG 229
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R SS L +
Sbjct: 230 KYECVATNSAGVRYSSPANLYV 251
Score = 31.9 bits (69), Expect = 7.6
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PRF+++ +I F+ C A DP WN G ++ +S + + G
Sbjct: 59 PRFIKEPKDQIGVSGGVASFV-CQATGDP--KPRVTWNKKGKKV-NSQRFETIEFDESAG 114
Query: 178 GELTIYNVSLS-DVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L I + D YECV ++++G I+ H +L + P G
Sbjct: 115 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 159
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 101 bits (242), Expect = 8e-21
Identities = 155/658 (23%), Positives = 251/658 (38%), Gaps = 62/658 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N S+A ++ +PSF + P+ VT C+ + P P
Sbjct: 233 MYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLAD--APVTFLCEVKGDPPPRLR 290
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W+K++ + G + I + +L I +S +DEG YTCVA+N G E+ G L V P+
Sbjct: 291 WRKEDGELPTG-RYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQL 349
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK--DSSDLYVNKRIKID-G 177
+ + ++ A SV F C +P A W G ++ S L R +
Sbjct: 350 VTQPQDQMAAPGESVAF-QCETKGNP--PPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG------PP----GPPGGVQILGI 227
G+L I V D G Y C S G I + L I+G PP GP +LG
Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGS 466
Query: 228 Q---RSSVTLEWTDS---NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
VT S +G+ + G L +T N T Y I NV E+D
Sbjct: 467 SVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY-----IANVQEMDMGFYSC 521
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
A ST W+ + +++ + P P+ PS P AP+ +
Sbjct: 522 VAKSSTGEATWSGW-LKMREDWGVSPDPPTEPS--------SPPGAPSQPVVTEITKNSI 572
Query: 342 TITWTPLPTSLQNGPGIHYKIF-------WR--RNGSEVEFQSLLLKKYGNIGTYVVHIS 392
T+TW P P + + F WR +G ++E ++ + I ++V
Sbjct: 573 TLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAV 632
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED-MPQVAPQLVSARSFNSTALNVTWNP 451
+ + + P V + + + +VA +L L V+W
Sbjct: 633 GAWGLSEPSPVSEPVRTQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWT- 691
Query: 452 IDQSRERLRGKLIGHRLKYWKQENKE--EECIYYLSRTTRNWALIVGLQPDTYYYVKVMA 509
+D + ++G + W+ E + L ++ ++ GL P T +KV A
Sbjct: 692 VDGPVQLVQGFRVS-----WRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQA 746
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNV--WAHDPTTLRVVWRYVQPTNEEEPLLGY 567
G G ES +AP PP V V +++ V W P+ + + Y
Sbjct: 747 QGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEY 806
Query: 568 KVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
++ W L + S + A + ++PG Y V A ++ G G S+P +
Sbjct: 807 QI--WCLGNE-SRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVL 861
Score = 84.6 bits (200), Expect = 1e-15
Identities = 63/219 (28%), Positives = 97/219 (44%), Gaps = 14/219 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKC-KPEAAPKPT 58
+Y C A+N L A+ S +A L V L+ F++ P + + G L+C P P+P+
Sbjct: 140 VYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVV--AVGEPAVLECVPPRGHPEPS 197
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDES-RGRLIVLRA 117
+W+KD + R G L++ + D G+Y CVA N G ES ++VL
Sbjct: 198 VSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLER 257
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P FL + ++ V FL C DP W K+ +L +
Sbjct: 258 PSFLRRPVNQVVLADAPVTFL-CEVKGDP--PPRLRWR------KEDGELPTGRYEIRSD 308
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VS D G Y CV ++++GR + L + PP
Sbjct: 309 HSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPP 347
Score = 65.7 bits (153), Expect = 5e-10
Identities = 50/178 (28%), Positives = 73/178 (41%), Gaps = 17/178 (9%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA-----GGKRFITENGNLIIRQL-----SR 89
S G TL C+ E P+P W K+ + R + +G L ++ +R
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRAR 135
Query: 90 DDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEKLPPRITAQVNSVVFLHCNADVDPIL 148
DEGVYTCVA+N G SR + + R + P + V L C
Sbjct: 136 PDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLEC-VPPRGHP 194
Query: 149 DTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ + W +G R+K+ RI I GG+L + + SD G Y CV + G S
Sbjct: 195 EPSVSWRKDGARLKEEEG-----RITIRGGKLMMSHTLKSDAGMYVCVASNMAGERES 247
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 101 bits (242), Expect = 8e-21
Identities = 155/658 (23%), Positives = 251/658 (38%), Gaps = 62/658 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N S+A ++ +PSF + P+ VT C+ + P P
Sbjct: 233 MYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLAD--APVTFLCEVKGDPPPRLR 290
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
W+K++ + G + I + +L I +S +DEG YTCVA+N G E+ G L V P+
Sbjct: 291 WRKEDGELPTG-RYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQL 349
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK--DSSDLYVNKRIKID-G 177
+ + ++ A SV F C +P A W G ++ S L R +
Sbjct: 350 VTQPQDQMAAPGESVAF-QCETKGNP--PPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG------PP----GPPGGVQILGI 227
G+L I V D G Y C S G I + L I+G PP GP +LG
Sbjct: 407 GQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGS 466
Query: 228 Q---RSSVTLEWTDS---NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRK 281
VT S +G+ + G L +T N T Y I NV E+D
Sbjct: 467 SVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY-----IANVQEMDMGFYSC 521
Query: 282 RATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDL 341
A ST W+ + +++ + P P+ PS P AP+ +
Sbjct: 522 VAKSSTGEATWSGW-LKMREDWGVSPDPPTEPS--------SPPGAPSQPVVTEITKNSI 572
Query: 342 TITWTPLPTSLQNGPGIHYKIF-------WR--RNGSEVEFQSLLLKKYGNIGTYVVHIS 392
T+TW P P + + F WR +G ++E ++ + I ++V
Sbjct: 573 TLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAV 632
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED-MPQVAPQLVSARSFNSTALNVTWNP 451
+ + + P V + + + +VA +L L V+W
Sbjct: 633 GAWGLSEPSPVSEPVRTQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWT- 691
Query: 452 IDQSRERLRGKLIGHRLKYWKQENKE--EECIYYLSRTTRNWALIVGLQPDTYYYVKVMA 509
+D + ++G + W+ E + L ++ ++ GL P T +KV A
Sbjct: 692 VDGPVQLVQGFRVS-----WRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQA 746
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNV--WAHDPTTLRVVWRYVQPTNEEEPLLGY 567
G G ES +AP PP V V +++ V W P+ + + Y
Sbjct: 747 QGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEY 806
Query: 568 KVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
++ W L + S + A + ++PG Y V A ++ G G S+P +
Sbjct: 807 QI--WCLGNE-SRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVL 861
Score = 84.6 bits (200), Expect = 1e-15
Identities = 63/219 (28%), Positives = 97/219 (44%), Gaps = 14/219 (6%)
Query: 1 MYQCEAKNQLKASYS-SAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKC-KPEAAPKPT 58
+Y C A+N L A+ S +A L V L+ F++ P + + G L+C P P+P+
Sbjct: 140 VYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVV--AVGEPAVLECVPPRGHPEPS 197
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDES-RGRLIVLRA 117
+W+KD + R G L++ + D G+Y CVA N G ES ++VL
Sbjct: 198 VSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLER 257
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P FL + ++ V FL C DP W K+ +L +
Sbjct: 258 PSFLRRPVNQVVLADAPVTFL-CEVKGDP--PPRLRWR------KEDGELPTGRYEIRSD 308
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +VS D G Y CV ++++GR + L + PP
Sbjct: 309 HSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPP 347
Score = 65.7 bits (153), Expect = 5e-10
Identities = 50/178 (28%), Positives = 73/178 (41%), Gaps = 17/178 (9%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGA-----GGKRFITENGNLIIRQL-----SR 89
S G TL C+ E P+P W K+ + R + +G L ++ +R
Sbjct: 76 SRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRAR 135
Query: 90 DDEGVYTCVAKNQYGTDESRGRLIVLRAPR-FLEKLPPRITAQVNSVVFLHCNADVDPIL 148
DEGVYTCVA+N G SR + + R + P + V L C
Sbjct: 136 PDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLEC-VPPRGHP 194
Query: 149 DTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ + W +G R+K+ RI I GG+L + + SD G Y CV + G S
Sbjct: 195 EPSVSWRKDGARLKEEEG-----RITIRGGKLMMSHTLKSDAGMYVCVASNMAGERES 247
>AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS
protein.
Length = 475
Score = 101 bits (241), Expect = 1e-20
Identities = 118/490 (24%), Positives = 204/490 (41%), Gaps = 51/490 (10%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVI---GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
T+ C P P TW KD + + + G+ +G L I D+G Y CVA N
Sbjct: 27 TMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNS 86
Query: 103 YGTDESRGRLIVLR----APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
G S + +R APRF LP V + C A P+ ++
Sbjct: 87 AGVRYSSPANLYVRVRRVAPRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAED 145
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
L +D D+ V + + ELT + D +Y CV S++G I + Q+ ++ P
Sbjct: 146 LTPED--DMPVGRNVL----ELT----DVKDSANYTCVAMSSLGVIEAVAQITVKSLPKA 195
Query: 219 PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN 278
PG + +S+T+ W N + P++ Y++ ++ Y I E+I RY+
Sbjct: 196 PGTPMVTENTATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS 249
Query: 279 GRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKT 338
L P + YE + A+N +G G PS S T P AP NV
Sbjct: 250 -------IGGLSPNSEYEIWVSAVNSIGQGPPS-ESVVTRTGEQAPASAPRNVQARMLSA 301
Query: 339 GDLTITW-TPL-PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYF 396
+ + W P+ P L G ++Y + E E +K+ + + + S
Sbjct: 302 TTMIVQWEEPVEPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLE 354
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSR 456
Y V+V AF +G GP S+ + + + + +P P + A + + T++ ++W+P Q
Sbjct: 355 DETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE- 412
Query: 457 ERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
+I + L + + ++ E + T+ ++ L+P+T Y ++ A + G G
Sbjct: 413 -----SIIKYELLFREGDHGREVGRTFDPTTS---YVVEDLKPNTEYAFRLAARSPQGLG 464
Query: 517 PESERYLERT 526
+ +RT
Sbjct: 465 AFTPVVRQRT 474
Score = 72.1 bits (169), Expect = 6e-12
Identities = 54/207 (26%), Positives = 101/207 (48%), Gaps = 12/207 (5%)
Query: 417 EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENK 476
E V + + +P+ AP +T++ +TW+ + + + +I ++ K +
Sbjct: 182 EAVAQITVKSLPK-APGTPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGPYQ 238
Query: 477 EEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
+E I TT ++ I GL P++ Y + V A NS G+GP SE + RT +AP P
Sbjct: 239 IKEDI-----TTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPR 292
Query: 537 SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYI 596
+V TT+ V W +P + GY+V + ++ + N ++ L +
Sbjct: 293 NVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTV 349
Query: 597 SNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+++ ++Y +RVLA+++ GDG +S P
Sbjct: 350 GSLLEDETYTVRVLAFTSVGDGPLSDP 376
Score = 70.1 bits (164), Expect = 2e-11
Identities = 74/280 (26%), Positives = 123/280 (43%), Gaps = 26/280 (9%)
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+TITW S P +Y I ++ + +Q +K+ +I T I + Y
Sbjct: 209 ITITWD----SGNPDPVSYYVIEYKSKSQDGPYQ---IKE--DITTTRYSIGGLSPNSEY 259
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERL 459
++ V A N IG GP SE V + E P AP+ V AR ++T + V W P++ +
Sbjct: 260 EIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPN---- 315
Query: 460 RGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGPE 518
G + G+R+ Y+ E + + + VG L D Y V+V+AF S G+GP
Sbjct: 316 -GLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 373
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S+ +T + P + P ++ A T++ + W P +E ++ Y++ E D
Sbjct: 374 SDPIQVKTQQGVPGQ-PMNLRAEARSETSITLSW---SPPRQES-IIKYELLFREGDHGR 428
Query: 579 STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
T P + + ++ P Y R+ A S G G
Sbjct: 429 EVGR-TFDPTTSYV---VEDLKPNTEYAFRLAARSPQGLG 464
Score = 50.8 bits (116), Expect = 2e-05
Identities = 85/358 (23%), Positives = 139/358 (38%), Gaps = 40/358 (11%)
Query: 2 YQCEAKNQLKASYSSAQ---LRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y+C A N YSS +RV + P F P+ E GGNV + C +P P
Sbjct: 79 YECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIM--PGGNVNITCVAVGSPMPY 136
Query: 59 FTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W + + + N ++ D YTCVA + G E+ ++ V P
Sbjct: 137 VKWMQGAEDLTPEDDMPVGRN---VLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLP 193
Query: 119 RFLEKLPPRITAQ-VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+ P +T S+ + + DP+ + Y+ + + K Y +IK D
Sbjct: 194 K--APGTPMVTENTATSITITWDSGNPDPV--SYYVIEY---KSKSQDGPY---QIKED- 242
Query: 178 GELTIYNV-SLSDVGDYECVVK--SAIGR--ISSHVQLRI--EGPPGPPGGVQILGIQRS 230
T Y++ LS +YE V ++IG+ S V R + P P VQ + +
Sbjct: 243 ITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSAT 302
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN-GRKRATVSTTL 289
++ ++W + I GY + +Y + P V ++N T +L
Sbjct: 303 TMIVQWEEPVEPNGLIRGYRV---------YYTMEPEHP-VGNWQKHNVDDSLLTTVGSL 352
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
L Y R+ A +G G S P Q T P + P N+ +T++W+P
Sbjct: 353 LEDETYTVRVLAFTSVGDGPLSDPI-QVKTQQGVPGQ-PMNLRAEARSETSITLSWSP 408
>AC005788-1|AAC62834.1| 1399|Homo sapiens PTPsigma [AA 524- 1926]
protein.
Length = 1399
Score = 100 bits (239), Expect = 2e-20
Identities = 93/366 (25%), Positives = 155/366 (42%), Gaps = 23/366 (6%)
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
EV R + V L P Y FR+ A + G G P + T KP P +V
Sbjct: 45 EVGRTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGA-FTPVVRQRTLQSKPSAPPQDVK 103
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS 392
++ + ++W P P NG + Y + +R GSE + + + T ++ +
Sbjct: 104 CVSVRSTAILVSWRPPPPETHNGALVGYSVRYRPLGSE-DPEPKEVNGIPPTTTQIL-LE 161
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPI 452
+ +T Y + A ++GPGPES V + + ED+P P+ V A + N+TA+ V W
Sbjct: 162 ALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSP 221
Query: 453 DQSRERLRGKLIGHRLKYWKQENKE------------EECIYYLSRTTRNWALIVGLQPD 500
R+ G++ G+++ Y + E E + + T +I LQP+
Sbjct: 222 APGRQ--HGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPE 279
Query: 501 TYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE 560
T Y + V A+ G+G S+ + T +P SV R W T E
Sbjct: 280 TAYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLAR--WEPPAGTAE 337
Query: 561 EEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRM 620
++ +LGY+++ D A P E + A S + G +Y R+ A S GG G
Sbjct: 338 DQ-VLGYRLQFGRED-STPLATLEFPPSEDRYTA--SGVHKGATYVFRLAARSRGGLGEE 393
Query: 621 SSPTIA 626
++ ++
Sbjct: 394 AAEVLS 399
Score = 53.2 bits (122), Expect = 3e-06
Identities = 86/427 (20%), Positives = 163/427 (38%), Gaps = 38/427 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS--NSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
P PP V+ + ++ +++ + W ++ + GY + R + P
Sbjct: 95 PSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYRP--------LGSEDPEPK 146
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
EV+ + L W Y A +GPG S+P T D P P V
Sbjct: 147 EVNGIPPTTTQILLEALEKWTQYRITTVAHTEVGPGPESSPVV-VRTDEDVPSAPPRKVE 205
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFW-RRNGSEVE----FQSLLLK----KYGN 383
+ + W Q+G Y++ + R G+E + ++L + +
Sbjct: 206 AEALNATAIRVLWRSPAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDD 265
Query: 384 IGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNST 443
Y + I++ T Y + V A+ G G S+ + + + + +S +
Sbjct: 266 TAEYEMVITNLQPETAYSITVAAYTMKGDGARSKPKVVVTKGAV--LGRPTLSVQQTPEG 323
Query: 444 ALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYY 503
+L W P + E +++G+RL++ ++++ + + R A G+ Y
Sbjct: 324 SLLARWEPPAGTAE---DQVLGYRLQFGREDSTPLATLEFPPSEDRYTAS--GVHKGATY 378
Query: 504 YVKVMAFNSAGEGPESERYL---ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE 560
++ A + G G E+ L E T R PQ A+ N A T+ + W P
Sbjct: 379 VFRLAARSRGGLGEEAAEVLSIPEDTPRGHPQILEAAGNASAG---TVLLRWLPPVPAER 435
Query: 561 EEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAY----ISNIIPGKSYNLRVLAYSNGG 616
++ Y V + E + A +T +P + A + + P +Y+L+V A++ G
Sbjct: 436 NGAIVKYTVAVREAGA-LGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRG 494
Query: 617 DGRMSSP 623
G S P
Sbjct: 495 PGPFSPP 501
Score = 48.8 bits (111), Expect = 6e-05
Identities = 41/194 (21%), Positives = 80/194 (41%), Gaps = 9/194 (4%)
Query: 432 PQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNW 491
P + A + + T++ ++W+P Q +I + L + + ++ E + T+
Sbjct: 5 PMNLRAEARSETSITLSWSPPRQE------SIIKYELLFREGDHGREVGRTFDPTTSY-- 56
Query: 492 ALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVV 551
++ L+P+T Y ++ A + G G + +RT + P PP V + T + V
Sbjct: 57 -VVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVS 115
Query: 552 WRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLA 611
WR P L+GY VR L + + + + + Y + +A
Sbjct: 116 WRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVA 175
Query: 612 YSNGGDGRMSSPTI 625
++ G G SSP +
Sbjct: 176 HTEVGPGPESSPVV 189
Score = 41.9 bits (94), Expect = 0.007
Identities = 72/299 (24%), Positives = 112/299 (37%), Gaps = 21/299 (7%)
Query: 285 VSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTIT 344
V T L P Y + A + G G S P T G +V G L
Sbjct: 272 VITNLQPETAYSITVAAYTMKGDGARSKPKVVV-TKGAVLGRPTLSVQQT--PEGSLLAR 328
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P P + Y++ + R S VH +TY + ++
Sbjct: 329 WEP-PAGTAEDQVLGYRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVF-----RL 382
Query: 405 QAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKL 463
A + G G E+ EV++I ED P+ PQ++ A N++A V + G +
Sbjct: 383 AARSRGGLGEEAAEVLSI--PEDTPRGHPQILEAAG-NASAGTVLLRWLPPVPAERNGAI 439
Query: 464 IGHRLKYWKQ----ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPES 519
+ + + + +E E N + GL+PDT Y ++V A G GP S
Sbjct: 440 VKYTVAVREAGALGPARETELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFS 499
Query: 520 ERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
RTF + Q P + V T++ + W + P N P YK++ L D+
Sbjct: 500 PPVRYRTFLR-DQVSPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 554
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 99 bits (238), Expect = 3e-20
Identities = 70/221 (31%), Positives = 102/221 (46%), Gaps = 13/221 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y C A N L + SSA+L +LS + P F P+ ++ E G T KC
Sbjct: 3851 YNCSASNPLGTASSSAKL-ILSEHEVPPFFDLKPVSVDLALGESG--TFKCHVTGTAPIK 3907
Query: 59 FTWKKDNIVIGAGG--KRFITEN-GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
TW KDN I GG K + EN L + ++ + D G YTC A N G D +L V
Sbjct: 3908 ITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 3967
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
PRF++KL P + + C P + LW + I++SS ++ +
Sbjct: 3968 EPPRFIKKLEPSRIVKQDEFTRYECKIGGSP--EIKVLWYKDETEIQESSKFRMSFVDSV 4025
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++N+S+ D GDY C +A G SS L+++ PP
Sbjct: 4026 --AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064
Score = 92.7 bits (220), Expect = 4e-18
Identities = 65/220 (29%), Positives = 93/220 (42%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N L + SSA+L K P F P+ ++ E + +C A
Sbjct: 2910 YSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESAD--FECHVTGAQPMRI 2967
Query: 60 TWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW KDN I GG IT GN L I ++ + D G YTC A N G D +L V
Sbjct: 2968 TWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE 3027
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P+F++KL A+ + L C P + ++ N + L ++ + +
Sbjct: 3028 PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL- 3086
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
LTI S D GDY C + +G S L ++ PP
Sbjct: 3087 ---LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 3123
Score = 85.4 bits (202), Expect = 6e-16
Identities = 59/219 (26%), Positives = 92/219 (42%), Gaps = 11/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+A N+ + +A L V + P+F P L T+ + C P
Sbjct: 191 YTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFI--CTVTGTPVIETI 248
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD + I++ N I +LS D GVY+C A N++G D + LI++
Sbjct: 249 WQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 308
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+++L P + + +N V L C D D W+ +G ++ D + KI
Sbjct: 309 PHFIKELEP-VQSAINKKVHLECQVDED--RKVTVTWSKDGQKLPPGKDYKICFEDKI-- 363
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I L D G Y C + G S + + PP
Sbjct: 364 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP 402
Score = 81.4 bits (192), Expect = 9e-15
Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 10/218 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + SAQL V P F K LE +G ++ L+CK +P+ +W
Sbjct: 3006 YTCQATNDVGKDMCSAQLSVKE-PPKFVKK-LEASKVAKQGESIQLECKISGSPEIKVSW 3063
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+++ + K FI L I + S +D G Y C A N G D S + ++AP
Sbjct: 3064 FRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG-DASCSTALTVKAP 3122
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ P + A S V L C P + +W + ++++S + K
Sbjct: 3123 PVFTQKPSPVGALKGSDVILQCEISGTPPFEV--VWVKDRKQVRNSKKFKITS--KHFDT 3178
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+ SDVG+Y C + +G + ++ + PP
Sbjct: 3179 NLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 3216
Score = 81.4 bits (192), Expect = 9e-15
Identities = 64/224 (28%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y E +N + +A L+V ++ PSF + L+ ET G G +V ++CK +P +
Sbjct: 4320 VYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRK-LK-ETNGLSGSSVVMECKVYGSPPIS 4377
Query: 59 FTWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
+W + I +G K T N L + L D G YTC+A N G+DE L V
Sbjct: 4378 VSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 4437
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F++K P +V F P + W K SS+L R +
Sbjct: 4438 EPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPF---SVSW------FKGSSELVPGDRCNV 4488
Query: 176 ----DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL +++V S G+Y C+V + G+ S L I+ P
Sbjct: 4489 SLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 4532
Score = 80.6 bits (190), Expect = 2e-14
Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE-GGNVTLKCKPEAAPKPTF 59
+Y C+A N+ A A+L ++ KP F K ELE S V L+C+ + K T
Sbjct: 285 VYSCKASNKFGADICQAELIIID-KPHFIK---ELEPVQSAINKKVHLECQVDEDRKVTV 340
Query: 60 TWKKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW KD + G F + L I D G Y C A N+ G+ + V
Sbjct: 341 TWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 400
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY-VNKRIKI 175
P F++K+ P LHC P++ + N+ L ++ +Y VN +
Sbjct: 401 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 460
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D I +V + D G Y C + +G S ++ I+ PP
Sbjct: 461 D-----ITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 496
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/218 (28%), Positives = 102/218 (46%), Gaps = 12/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N ++ SS L+V P F+K P +ET +G +V L+C+ + P +W
Sbjct: 4041 YTCEAHNAAGSASSSTSLKVKE-PPIFRKKPHPIETL--KGADVHLECELQGTPPFHVSW 4097
Query: 62 KKDNIVIGAGGK-RFITENGNLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD + +G K + ++EN I L+ D D G Y C A N G+D G + + P
Sbjct: 4098 YKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 4157
Query: 119 RFLEKLPPRITAQVNSVVFLHCNAD-VDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
RF++KL I+ V V L + +PI + + G +++S +++++ I
Sbjct: 4158 RFVKKLSD-ISTVVGKEVQLQTTIEGAEPI--SVVWFKDKGEIVRESDNIWISYSENI-- 4212
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L V ++ G Y C +K+ G L + P
Sbjct: 4213 ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP 4250
Score = 73.7 bits (173), Expect = 2e-12
Identities = 56/219 (25%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ +S SA + V PSF K ++ G + L CK + +P TW
Sbjct: 379 YVCTASNEAGSSSCSATVTVRE-PPSFVKK-VDPSYLMLPGESARLHCKLKGSPVIQVTW 436
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K+N + F+ L I + +D G Y+C A N G+D +++ P
Sbjct: 437 FKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 496
Query: 119 RFLEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
F++ L P I N++ L C + ++ + +R L+ K +
Sbjct: 497 SFIKTLEPADIVRGTNAL--LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC-- 552
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I++ + +DVG+YECVV + +G+ ++ PP
Sbjct: 553 --LEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPP 589
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/250 (26%), Positives = 103/250 (41%), Gaps = 11/250 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N + + S A L V P F K P + + G + T +C+ PK +W
Sbjct: 1503 YICQLSNDVGTATSKATLFVKE-PPQFIKKPSPVLVLRN-GQSTTFECQITGTPKIRVSW 1560
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
D I A K I+ L Q+S ++ G Y C A+N GT L V P
Sbjct: 1561 YLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 1620
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F+ +L P + S V L C P + W N I+ S + R+ +
Sbjct: 1621 TFIRELKP-VEVVKYSDVELECEVTGTPPFEVT--WLKNNREIRSSKKYTLTDRVSV--F 1675
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ-ILGIQRSSVTLEWT 237
L I SD G+Y+C+V + G S ++ ++ PP ++ + +SS T + T
Sbjct: 1676 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQST 1735
Query: 238 DSNSNGRPIT 247
+ S IT
Sbjct: 1736 VAGSPPISIT 1745
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/222 (25%), Positives = 94/222 (42%), Gaps = 18/222 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C N + S S + +++ P F K LE G + L+CK +P+ W
Sbjct: 2065 YTCHVTNDV-GSDSCTTMLLVTEPPKFVKK-LEASKIVKAGDSSRLECKIAGSPEIRVVW 2122
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
++ + A K FI + + LS +D G + C A+N G+ ++IV P
Sbjct: 2123 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 2182
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F PP + N+ V L C P + +W KD L +K+ KI
Sbjct: 2183 VF-SSFPPIVETLKNAEVSLECELSGTPPFEV--VW------YKDKRQLRSSKKYKIASK 2233
Query: 179 E----LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I NV SD+G+Y C ++ +G + ++++ PP
Sbjct: 2234 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 2275
Score = 69.7 bits (163), Expect = 3e-11
Identities = 67/242 (27%), Positives = 99/242 (40%), Gaps = 16/242 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC+A N + + + L P F K ++ T G V L+ E A + W
Sbjct: 4134 YQCKATNDVGSDTCVGSI-ALKAPPRFVKKLSDISTV--VGKEVQLQTTIEGAEPISVVW 4190
Query: 62 KKDN-IVIGAGGKRFITENGNLIIRQLSRDDE---GVYTCVAKNQYGTDESRGRLIVLRA 117
KD ++ +I+ + N+ Q SR + G YTC KN G E L VL
Sbjct: 4191 FKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP 4250
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+EK P I L C P L T W +G + + ++ K+ G
Sbjct: 4251 ATIVEK-PESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYKISFFNKVSG 4307
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL----GIQRSSVT 233
L I NV+ SD G Y V++ +G+ S L++ PP + L G+ SSV
Sbjct: 4308 --LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVV 4365
Query: 234 LE 235
+E
Sbjct: 4366 ME 4367
Score = 69.3 bits (162), Expect = 4e-11
Identities = 60/219 (27%), Positives = 97/219 (44%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y + +N + S +A + V ++ PSF + L+ T G G + L+CK + +
Sbjct: 2439 YTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRR-LK-NTGGVLGASCILECKVAGSSPISV 2496
Query: 60 TW--KKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W +K IV GA + ++N L + L D G YTCVA N G+DE R L V
Sbjct: 2497 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 2556
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+++ P +V F P + L D ++Y +
Sbjct: 2557 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPP-FKVNWFRGARELVKGDRCNIYFEDTV--- 2612
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL ++N+ +S G+Y CVV + G+ S +L ++ P
Sbjct: 2613 -AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 2650
Score = 68.1 bits (159), Expect = 9e-11
Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 8/181 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT--ENGNLI-IRQLSRDDEGVYTCV 98
G + L+ P + +W KD +I + IT E ++ I + + +D Y+C+
Sbjct: 3606 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 3665
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N+ G D + VL P F+E L + A + L C D P + ++ H
Sbjct: 3666 IENEAGQDICEALVSVLEPPYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKEHTK 3724
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
LR S+ Y + K + L I V SDVG+Y C +++G ++S L I+ P
Sbjct: 3725 LR---SAPAY-KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLP 3780
Query: 219 P 219
P
Sbjct: 3781 P 3781
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL--KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y E +N + S A++ VL L PSF K ++++ +G + L+C + +
Sbjct: 1314 YTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSI--KGSFIDLECIVAGSHPISI 1371
Query: 60 TWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD+ I A K + + N L I QL D G YTC A N+ G ++ G L V
Sbjct: 1372 QWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 1431
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+EK P+ + VN + A V W + + + V K
Sbjct: 1432 PPYFVEK--PQ-SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWK--DDT 1486
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ +D G Y C + + +G +S L ++ PP
Sbjct: 1487 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 1526
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 15/219 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKH--PLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y CEA+N + S +L+V P+F + P+E+ Y +V L+C+ P
Sbjct: 1597 YVCEARNDAGTASCSIELKVKE-PPTFIRELKPVEVVKYS----DVELECEVTGTPPFEV 1651
Query: 60 TWKKDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW K+N I + K +T+ NL I + D G Y C+ N+ G+ R+ +
Sbjct: 1652 TWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 1711
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F++K+ T +S F A PI T W + + + ++Y++ +
Sbjct: 1712 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT---WLKDDQILDEDDNVYISFVDSV- 1767
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L I +V G Y C K+ G + L ++ P
Sbjct: 1768 -ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 1805
Score = 63.7 bits (148), Expect = 2e-09
Identities = 52/223 (23%), Positives = 91/223 (40%), Gaps = 12/223 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N+ A + VL +P + PLE G TL+CK + P+ +W
Sbjct: 3662 YSCLIENEAGQDICEALVSVL--EPPYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISW 3718
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL--R 116
K++ + + +F +L+I ++ D G Y+C A N G S L++ +
Sbjct: 3719 YKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK 3778
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F + + + V C + L + W +G+ +KD ++L + +
Sbjct: 3779 LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVS--WYKDGVLLKDDANLQTSFVHNV- 3835
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I S +G Y C + +G SS +L + PP
Sbjct: 3836 -ATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 3877
Score = 63.3 bits (147), Expect = 3e-09
Identities = 55/222 (24%), Positives = 89/222 (40%), Gaps = 13/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK-PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+A N + A SSA L + + K P F L+ + + + G V +C+ + +
Sbjct: 3755 YSCKADNSVGAVASSAVLVIKARKLPPFFARKLK-DVHETLGFPVAFECRINGSEPLQVS 3813
Query: 61 WKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-- 115
W KD +++ F+ L I Q + G Y C A N GT S +LI+
Sbjct: 3814 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEH 3873
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P F + P + + C+ PI T W + I+ + + +
Sbjct: 3874 EVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT---WAKDNREIRPGGNYKMT--LV 3928
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ LT+ V D G Y C + G+ S QL ++ PP
Sbjct: 3929 ENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 3970
Score = 63.3 bits (147), Expect = 3e-09
Identities = 62/222 (27%), Positives = 87/222 (39%), Gaps = 18/222 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N SAQL V P F K LE + +CK +P+ W
Sbjct: 3947 YTCYASNIAGKDSCSAQLGVQE-PPRFIKK-LEPSRIVKQDEFTRYECKIGGSPEIKVLW 4004
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I K F+ L + LS +D G YTC A N G+ S L V P
Sbjct: 4005 YKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
F +K P I + V L C P ++ KD +L K+ KI
Sbjct: 4065 IFRKK-PHPIETLKGADVHLECELQGTPPFHVSW--------YKDKRELRSGKKYKIMSE 4115
Query: 178 ---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I NV +D+G+Y+C + +G + + ++ PP
Sbjct: 4116 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 4157
Score = 62.9 bits (146), Expect = 4e-09
Identities = 54/204 (26%), Positives = 81/204 (39%), Gaps = 10/204 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
+ C A N + + SS L ++ PSF P + G V LK + + T W
Sbjct: 848 FTCRATNSVGSKDSSGAL-IVQEPPSFVTKPGSKDVL--PGSAVCLKSTFQGSTPLTIRW 904
Query: 62 KKDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K N + +GG +IT+ +L + + D G YTC N G E L V
Sbjct: 905 FKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F+EKL P + L C P + W N IK+SS ++
Sbjct: 965 TFVEKLEPSQLLKKGDATQLACKVTGTPPIKIT--WFANDREIKESSKHRMS--FVESTA 1020
Query: 179 ELTIYNVSLSDVGDYECVVKSAIG 202
L + +V + D G+Y C ++ G
Sbjct: 1021 VLRLTDVGIEDSGEYMCEAQNEAG 1044
Score = 62.1 bits (144), Expect = 6e-09
Identities = 58/223 (26%), Positives = 90/223 (40%), Gaps = 15/223 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPS-FKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
Y C N A +S R+ +P+ F K L + E G ++ L+ +
Sbjct: 2628 YTCVVSNN--AGQASCTTRLFVKEPAAFLKR---LSDHSVEPGKSIILESTYTGTLPISV 2682
Query: 60 TWKKDNIVIGAGGK-RFITENGNLIIRQLS--RDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TWKKD I K +T I+ L+ + D G Y+C +N+ G D + L
Sbjct: 2683 TWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE 2742
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+ +L P + A V V L C P + ++ LR Y +
Sbjct: 2743 PPYFVTELEP-LEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNV--- 2798
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L V+++D G+Y C +++IG SS RI+ PP
Sbjct: 2799 -ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPP 2840
Score = 61.7 bits (143), Expect = 8e-09
Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 13/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN-VTLKCKPEAAPKPTFT 60
Y C N+ A +S + P+ K L Y E G + L+ P + T
Sbjct: 4510 YTCIVSNE--AGKASCTTHLYIKAPA--KFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 4565
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRA 117
WKK+ I + + IT I ++ +D G Y C +N G D ++++L
Sbjct: 4566 WKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 4625
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+++L P + V L C P + + W +++ ++ ++ R +
Sbjct: 4626 PYFVKQLEP-VKVSVGDSASLQCQLAGTPEIGVS--WYKGDTKLRPTTTYKMHFRNNV-- 4680
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L V ++D G+Y C ++++G +S+ L ++ PP
Sbjct: 4681 ATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPP 4722
Score = 61.3 bits (142), Expect = 1e-08
Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 16/227 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N + ++ SSA+L + K P F ++ E + +C
Sbjct: 4792 YSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESAD--FECHVTGTQPIKV 4849
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV-- 114
+W KD+ I +GGK ++ + +L + ++ + D G YTC A N+ G D +L +
Sbjct: 4850 SWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 4909
Query: 115 -LRAPRFLEKLPPRI-TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
L P F ++L + + NS A PI W N + I+ +S+ +
Sbjct: 4910 RLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPI---TVAWYKNNIEIQPTSNCEIT-- 4964
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
K + L + ++D G Y C V + G + I+ P PP
Sbjct: 4965 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 5011
Score = 60.9 bits (141), Expect = 1e-08
Identities = 57/220 (25%), Positives = 88/220 (40%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y + +N +S A LRVL ++ PSF K +++ G ++ ++CK + +
Sbjct: 1876 YTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV--LGSSIHMECKVSGSLPISA 1933
Query: 60 TWKKDNIVIGAGGK-RFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I K R + + L + L +D YTC N G D G L V
Sbjct: 1934 QWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 1993
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P FL K P R A +S V P W + + + ++ ++
Sbjct: 1994 PPSFLVK-PGRQQAIPDSTVEFKAILKGTPPFKIK--WFKDDVELVSGPKCFIG--LEGS 2048
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +Y+V S G Y C V + +G S L + PP
Sbjct: 2049 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 2088
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N S L V PSF P + V K + P W
Sbjct: 1972 YTCKVSNVAGDDACSGILTVKE-PPSFLVKPGRQQAIPDS--TVEFKAILKGTPPFKIKW 2028
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD++ + +G K FI G+ L + + G YTC N G+D L+V P
Sbjct: 2029 FKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 2088
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
+F++KL + L C P + + N + L +SD Y + ID
Sbjct: 2089 KFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHEL---PASDKY--RMTFIDSV 2143
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + N+S D GD+ C ++ G S ++ ++ PP
Sbjct: 2144 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 2182
Score = 60.1 bits (139), Expect = 3e-08
Identities = 55/219 (25%), Positives = 82/219 (37%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y E N++ +S VL + P F K PL G L CK +
Sbjct: 752 YTFEISNEVGSSSCETTFTVLDRDIAPFFTK-PLR-NVDSVVNGTCRLDCKIAGSLPMRV 809
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+W KD I A + F+ +L I ++ +D G +TC A N G+ +S G LIV
Sbjct: 810 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 869
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+ K + ++V P+ W + Y+ K
Sbjct: 870 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPL---TIRWFKGNKELVSGGSCYITKEAL-- 924
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L +Y V SD G Y C V + G + L ++ P
Sbjct: 925 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEP 963
Score = 59.3 bits (137), Expect = 4e-08
Identities = 50/219 (22%), Positives = 82/219 (37%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + S L V P F + P + + V LK T W
Sbjct: 1410 YTCSATNKAGHNQCSGHLTVKE-PPYFVEKPQSQDV--NPNTRVQLKALVGGTAPMTIKW 1466
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQL---SRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KDN + +G R + ++ +L D G Y C N GT S+ L V P
Sbjct: 1467 FKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 1526
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
+F++K P + + C P + ++ + N + + IDG
Sbjct: 1527 QFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-----IDGL 1581
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + + G Y C ++ G S ++L+++ PP
Sbjct: 1582 ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 1620
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/221 (26%), Positives = 84/221 (38%), Gaps = 14/221 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ KN A L VL +K P ++ + G TL+C P+ + W
Sbjct: 4228 YTCQIKNDAGMQECFATLSVLEPATIVEK-PESIKV--TTGDTCTLECTVAGTPELSTKW 4284
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA- 117
KD + + K F + L I ++ D GVY+ +N G D L V
Sbjct: 4285 FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 4344
Query: 118 --PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F KL +SVV + C P + + W H G I SS +
Sbjct: 4345 VPPSFTRKLKETNGLSGSSVV-MECKVYGSPPISVS--WFHEGNEI--SSGRKYQTTLTD 4399
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ LT+ + SD GDY C+ + G L + PP
Sbjct: 4400 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPP 4440
Score = 57.2 bits (132), Expect = 2e-07
Identities = 52/218 (23%), Positives = 88/218 (40%), Gaps = 11/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + SA L V PSF + P ++ G NVT + P + +W
Sbjct: 4417 YTCIATNMAGSDECSAPLTVRE-PPSFVQKPDPMDVL--TGTNVTFTSIVKGTPPFSVSW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDD---EGVYTCVAKNQYGTDESRGRLIVLRAP 118
K + + G + ++ ++ +L D G YTC+ N+ G L +
Sbjct: 4474 FKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 4533
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+F+++L + ++ PI T W NG+ + S + K
Sbjct: 4534 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVT---WKKNGINVTPSQRCNITTTEK--SP 4588
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I + ++ D G Y C +++A G+ S Q+ I PP
Sbjct: 4589 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP 4626
Score = 56.4 bits (130), Expect = 3e-07
Identities = 50/218 (22%), Positives = 84/218 (38%), Gaps = 10/218 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N SA L V +P+ LE +G L CK P TW
Sbjct: 941 YTCKVSNVAGGVECSANLFVK--EPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITW 998
Query: 62 KKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
++ I K F+ L + + +D G Y C A+N+ G+D +IV +P
Sbjct: 999 FANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 1058
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F ++ P + V+ L A P + + ++ LR ++ +
Sbjct: 1059 YFTKEFKPIEVLKEYDVMLLAEVAGTPP-FEITWFKDNTILRSGRKYKTFIQDHLV---- 1113
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +D G+Y+C V + +G ++ + PP
Sbjct: 1114 SLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 1151
Score = 56.4 bits (130), Expect = 3e-07
Identities = 54/224 (24%), Positives = 86/224 (38%), Gaps = 17/224 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C+A+N + + S R+ L PSF + ++E + G VTL C+ +
Sbjct: 2814 YTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ--TVGLPVTLTCRLNGSAPIQV 2871
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W +D +++ F+ L I Q G Y+C A N GT S RL R
Sbjct: 2872 CWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL-TAR 2930
Query: 117 APR---FLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
P+ F + P I C+ P+ T W+ + I+ + +
Sbjct: 2931 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRIT---WSKDNKEIRPGGNYTIT-- 2985
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ L I V D G Y C + +G+ QL ++ PP
Sbjct: 2986 CVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPP 3029
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/249 (25%), Positives = 99/249 (39%), Gaps = 22/249 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C+A+N + +S L V K PSF + +++ + G V C + +
Sbjct: 4696 YICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQE--TVGLPVVFDCAISGSEPISV 4753
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL- 115
+W KD + F+ L I + R G Y+C A N G+ S RLI+
Sbjct: 4754 SWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTE 4813
Query: 116 -RAPRFLE-KLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
+ P F + +L P + A V C+ PI W + I+ ++
Sbjct: 4814 GKNPPFFDIRLAP-VDAVVGESADFECHVTGTQPI---KVSWAKDSREIRSGGKYQIS-- 4867
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSV 232
+ LT+ V D G Y C + +G+ S QL I+ PP +R S
Sbjct: 4868 YLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-----KRLSE 4922
Query: 233 TLEWTDSNS 241
T+E T+ NS
Sbjct: 4923 TVEETEGNS 4931
Score = 54.8 bits (126), Expect = 9e-07
Identities = 54/220 (24%), Positives = 89/220 (40%), Gaps = 12/220 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y E KN + S + + V + PSF + ++ G +V L+C+ + +
Sbjct: 3379 LYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAI--LGASVVLECRVSGSAPIS 3436
Query: 59 FTWKKDN--IVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W +D IV G + +EN L + L D G+YTCVA N G+DE L V
Sbjct: 3437 VGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 3496
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F E+ P + + P + L +S ++ + +
Sbjct: 3497 EPPSF-EQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVT- 3554
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL ++ V + GDY C+V + G S L ++ P
Sbjct: 3555 ---ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP 3591
Score = 54.4 bits (125), Expect = 1e-06
Identities = 59/207 (28%), Positives = 87/207 (42%), Gaps = 16/207 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + S L V + P F + P + +G +V L+C+ P W
Sbjct: 3100 YICEAHNGVGDASCSTALTVKA-PPVFTQKPSPVGAL--KGSDVILQCEISGTPPFEVVW 3156
Query: 62 KKDNIVIGAGGKRFITE---NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD + K IT + NL I L D G Y C A N+ G+D + P
Sbjct: 3157 VKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 3216
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW-NHNGLRIKDSSDLYVNKRIK-ID 176
RF++KL T ++V A V+ + +W G I++S N RI ID
Sbjct: 3217 RFVKKLSDTSTLIGDAV---ELRAIVEGFQPISVVWLKDRGEVIRESE----NTRISFID 3269
Query: 177 G-GELTIYNVSLSDVGDYECVVKSAIG 202
L + + S+ G Y C +K+ G
Sbjct: 3270 NIATLQLGSPEASNSGKYICQIKNDAG 3296
Score = 54.0 bits (124), Expect = 2e-06
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 16/248 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N++ + S ++ P F K + T G V L+ E + W
Sbjct: 3193 YHCKATNEVGSDTCSCSVKFKE-PPRFVKKLSDTSTL--IGDAVELRAIVEGFQPISVVW 3249
Query: 62 KKDN--IVIGAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
KD ++ + R FI L + + G Y C KN G E L VL
Sbjct: 3250 LKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 3309
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
R +EK P +T + L C P L W +G + S ++ K+
Sbjct: 3310 ARIIEK-PEPMTVTTGNPFALECVVTGTPELSAK--WFKDGRELSADSKHHITFINKV-- 3364
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL----GIQRSSVT 233
L I +SD G Y VK+++G+ + V + + PP ++ L I +SV
Sbjct: 3365 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVV 3424
Query: 234 LEWTDSNS 241
LE S S
Sbjct: 3425 LECRVSGS 3432
Score = 53.2 bits (122), Expect = 3e-06
Identities = 55/207 (26%), Positives = 83/207 (40%), Gaps = 11/207 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C N++ A +L P+F K +L G G VTL+ + + TW
Sbjct: 566 YECVVANEVGKCGCMAT-HLLKEPPTFVKKVDDLIALG--GQTVTLQAAVRGSEPISVTW 622
Query: 62 KKDNIVIGAGGK-RFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K VI GK + NG LII + G YTC+A+N+ G+ S G LIV
Sbjct: 623 MKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPA 682
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +E+ I L P L W +G + S ++ K +
Sbjct: 683 KIIER-AELIQVTAGDPATLEYTVAGTPELKPK--WYKDGRPLVASKKYRIS--FKNNVA 737
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRIS 205
+L Y+ L D G Y + + +G S
Sbjct: 738 QLKFYSAELHDSGQYTFEISNEVGSSS 764
Score = 52.8 bits (121), Expect = 4e-06
Identities = 45/173 (26%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 49 CKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRD---DEGVYTCVAKNQYGT 105
C+ ++AP F W K I K I + + ++ R D G YTC A N+YG+
Sbjct: 142 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 201
Query: 106 DESRGRLIVLRA--PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKD 163
L V A P FL + P +T V C P+++T +W +G +
Sbjct: 202 VSCTATLTVTEAYPPTFLSR-PKSLTTFVGKAAKFICTVTGTPVIET--IWQKDGAALSP 258
Query: 164 SSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
S + ++ EL+ N+++ D G Y C + G +L I P
Sbjct: 259 SPNWRISDAENKHILELS--NLTIQDRGVYSCKASNKFGADICQAELIIIDKP 309
Score = 52.4 bits (120), Expect = 5e-06
Identities = 56/221 (25%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N+ S S + L PSF K +E T + + T + +P + TW
Sbjct: 1690 YQCIVSNE-GGSCSCSTRVALKEPPSFIKK-IENTTTVLKS-SATFQSTVAGSPPISITW 1746
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD+ ++ F+ L IR + G YTC AKN+ G + L+V
Sbjct: 1747 LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPA 1806
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +EK + + L C P L W +G +I S Y + + +
Sbjct: 1807 QIVEK-AKSVDVTEKDPMTLECVVAGTPELKVK--WLKDGKQIVPSR--YFSMSFENNVA 1861
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
I +V D G Y V++ G S LR+ PP
Sbjct: 1862 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPP 1902
Score = 51.6 bits (118), Expect = 9e-06
Identities = 51/221 (23%), Positives = 92/221 (41%), Gaps = 19/221 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA+N+ + + S+ + ++ P F K +E +V L + P TW
Sbjct: 1035 YMCEAQNEAGSDHCSS-IVIVKESPYFTKEFKPIEVLKEY--DVMLLAEVAGTPPFEITW 1091
Query: 62 KKDNIVIGAGGK--RFITEN-GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KDN ++ +G K FI ++ +L I + D G Y C N+ G+ R+ + P
Sbjct: 1092 FKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 1151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV--NKRIKID 176
F++K+ + + + F A + L W +KDS ++ N R+ +
Sbjct: 1152 SFIKKIESTSSLRGGTAAF---QATLKGSLPITVTW------LKDSDEITEDDNIRMTFE 1202
Query: 177 GGELTIY--NVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
++Y + + G Y C K+ G L ++ P
Sbjct: 1203 NNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP 1243
Score = 50.0 bits (114), Expect = 3e-05
Identities = 54/205 (26%), Positives = 70/205 (34%), Gaps = 11/205 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + A L V PSF K P LE G NVT P W
Sbjct: 2535 YTCVAANVAGSDECRAVLTVQE-PPSFVKEPEPLEVL--PGKNVTFTSVIRGTPPFKVNW 2591
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+ + G + F L + + G YTCV N G RL V
Sbjct: 2592 FRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA 2651
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
FL++L S++ PI T W +G I S + K
Sbjct: 2652 AFLKRLSDHSVEPGKSIILESTYTGTLPISVT---WKKDGFNITTSEKCNIVTTEKT--C 2706
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGR 203
L I N + D G Y C +++ GR
Sbjct: 2707 ILEILNSTKRDAGQYSCEIENEAGR 2731
Score = 49.2 bits (112), Expect = 5e-05
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ KN + A L VL +K T G TL+CK P+ + W
Sbjct: 2346 YICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGE---TCTLECKVAGTPELSVEW 2402
Query: 62 KKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RA 117
KD ++ + K F + +L I + R D G YT +N G + V RA
Sbjct: 2403 YKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 2462
Query: 118 --PRFLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P F +L + + L C A PI + W H +I +
Sbjct: 2463 VPPSFTRRLK-NTGGVLGASCILECKVAGSSPI---SVAWFHEKTKIVSGAKYQTTFSDN 2518
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ L + ++ SD+G+Y CV + G L ++ PP
Sbjct: 2519 VC--TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 2558
Score = 49.2 bits (112), Expect = 5e-05
Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 19/234 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+ KN SA L VL +K P+ + T G L+C P+ +
Sbjct: 3287 YICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTT----GNPFALECVVTGTPELSAK 3342
Query: 61 WKKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV--- 114
W KD + A K FI + +L I D+G+Y+ KN G + V
Sbjct: 3343 WFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 3402
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
+ P F+ KL + A + + V L C + W +G I +
Sbjct: 3403 IVPPSFIRKLKD-VNAILGASVVLECRVSGSAPISVG--WFQDGNEIVSGPKCQSSFSEN 3459
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG---PPGGVQIL 225
+ L++ + SD G Y CV + G L ++ PP P V++L
Sbjct: 3460 VCTLNLSL--LEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 3511
Score = 48.4 bits (110), Expect = 8e-05
Identities = 72/285 (25%), Positives = 114/285 (40%), Gaps = 25/285 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTFT 60
Y C A+N+ + S +L V ++ L T G T+ PE PK
Sbjct: 659 YTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPK---- 714
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLR- 116
W KD + A K I+ N+ ++ S + D G YT N+ G+ VL
Sbjct: 715 WYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR 774
Query: 117 --APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
AP F + L + + VN L C + L W +G I +SD Y RI
Sbjct: 775 DIAPFFTKPLR-NVDSVVNGTCRLDCK--IAGSLPMRVSWFKDGKEIA-ASDRY---RIA 827
Query: 175 -IDG-GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG---PPGGVQILGIQR 229
++G L I V ++D G++ C +++G S L ++ PP PG +L
Sbjct: 828 FVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVL--PG 885
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
S+V L+ T S I + + Y+ E + + +E+
Sbjct: 886 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLEL 930
Score = 47.6 bits (108), Expect = 1e-04
Identities = 55/240 (22%), Positives = 98/240 (40%), Gaps = 12/240 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + S ++ V+ PSF K LE G N L+C+ +W
Sbjct: 473 YSCEAVNDVGSDSCSTEI-VIKEPPSFIK-TLEPADI-VRGTNALLQCEVSGTGPFEISW 529
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQL---SRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I + K + +L+ ++ + D G Y CV N+ G ++ P
Sbjct: 530 FKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPP 589
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F++K+ I +V +PI T W I++ + ++ +
Sbjct: 590 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVT---WMKGQEVIREDGKIKMSFSNGV--A 644
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I +V +S G Y C+ ++ G +S +L ++ P +++ + TLE+T
Sbjct: 645 VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 704
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Query: 4 CEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKK 63
CEA+N ++ S ++ ++ P F P +ET + V+L+C+ P W K
Sbjct: 2161 CEAQNPAGSTSCSTKV-IVKEPPVFSSFPPIVETL--KNAEVSLECELSGTPPFEVVWYK 2217
Query: 64 DNIVIGAGGK-RFITENGNLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
D + + K + ++N + I L+ D D G Y C A+N+ G+D + + PRF
Sbjct: 2218 DKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRF 2277
Query: 121 LEKL 124
+ KL
Sbjct: 2278 VSKL 2281
Score = 46.4 bits (105), Expect = 3e-04
Identities = 50/233 (21%), Positives = 91/233 (39%), Gaps = 26/233 (11%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y C+ N ++ ++ + + K P F +H + SEG V L C + +
Sbjct: 4984 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTV--SEGEYVQLSCHVQGSEPIR 5041
Query: 59 FTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W K I + F + L +R +++ D G Y C A N G+D ++ ++ +
Sbjct: 5042 IQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 5101
Query: 116 RAPR--------------FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR- 160
P F P I + DPI + W R
Sbjct: 5102 DKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK--WTKGKWRQ 5159
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
+ +++++ K D +L I + + +D G Y CV + G I S+V L+++
Sbjct: 5160 LNQGGRVFIHQ--KGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVD 5210
Score = 44.4 bits (100), Expect = 0.001
Identities = 52/222 (23%), Positives = 82/222 (36%), Gaps = 12/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A+N++ + ++ L P F L E L+ E A W
Sbjct: 2252 YHCKAQNEVGSDTCVCTVK-LKEPPRFVSKLNSLTVVAGEPAE--LQASIEGAQPIFVQW 2308
Query: 62 --KKDNIVIGAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+K+ ++ + R F+ L + + G Y C KN G E+ L+VL
Sbjct: 2309 LKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEP 2368
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+EK P +T V L C P L W +G + S + KI
Sbjct: 2369 AVIVEKAGP-MTVTVGETCTLECKVAGTPELSVE--WYKDGKLLTSSQKHKFSFYNKI-- 2423
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I +V D G Y V++ +G+ S + + PP
Sbjct: 2424 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPP 2465
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 5/113 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNI-VIGAGGKRFITENGN---LIIRQLSRDDEGVYT 96
E T K P P W K + GG+ FI + G+ L IR ++ D G+Y
Sbjct: 5132 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYR 5191
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILD 149
CVA N++G ES L V + EK+ + A + L A + +D
Sbjct: 5192 CVAFNEHGEIESNVNLQVDERKK-QEKIEGDLRAMLKKTPILKKGAGEEEEID 5243
Score = 38.3 bits (85), Expect = 0.087
Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 9/129 (6%)
Query: 18 QLRVLSLKPSFKKHPLELETYGSE--GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-R 74
QL+ + LK F K ++ SE G + +C + T TW KD I K R
Sbjct: 7796 QLKAVPLK--FVKEIKDIILTESEFVGSSAIFECLVSPSTAIT-TWMKDGSNIRESPKHR 7852
Query: 75 FITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP-RFLEKLPPRITAQ 131
FI + + L I + D G YTCV + S +L+V P RF++ L +T
Sbjct: 7853 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVV 7912
Query: 132 VNSVVFLHC 140
++L C
Sbjct: 7913 KGQPLYLSC 7921
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 99 bits (238), Expect = 3e-20
Identities = 139/592 (23%), Positives = 241/592 (40%), Gaps = 62/592 (10%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL---SLKPSFKKHPLELETYGSEGGNV-TLKCKPEAAPK 56
+Y+C A+N + A+L VL L F + + E T+ C P
Sbjct: 104 VYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASGNPD 163
Query: 57 PTFTWKKDNIVI---GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P TW KD + + + G+ +G L I D+G Y CVA N G S +
Sbjct: 164 PEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYSSPANL 223
Query: 114 VLR----APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
+R APRF LP V + C A P+ ++ L +D D+ V
Sbjct: 224 YVRVRRVAPRF-SILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPED--DMPV 280
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYE-CVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ + ELT + D +Y CV S++G I + Q+ ++ P PG +
Sbjct: 281 GRNVL----ELT----DVKDSANYHPCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 332
Query: 229 RSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTT 288
+S+T+ W N + P++ Y++ ++ Y I E+I RY+
Sbjct: 333 ATSITITWDSGNPD--PVSYYVIEYKSKSQDGPYQIKEDITTT----RYS-------IGG 379
Query: 289 LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW-TP 347
L P + YE + A+N +G G PS S T P P NV + + W P
Sbjct: 380 LSPNSEYEIWVSAVNSIGQGPPS-ESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEP 438
Query: 348 L-PTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
+ P L G ++Y + E E +K+ + + + S Y V+V A
Sbjct: 439 VEPNGLIRGYRVYYTM-------EPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLA 491
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
F +G GP S+ + + + + +P P + A + + T++ ++W+P Q +I +
Sbjct: 492 FTSVGDGPLSDPIQVKTQQGVPG-QPMNLRAEARSETSITLSWSPPRQE------SIIKY 544
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERT 526
L + + ++ E + T+ ++ L+P+T Y ++ A + G G + +RT
Sbjct: 545 ELLFREGDHGREVGRTFDPTTS---YVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRT 601
Query: 527 FRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
+ P + V T++ + W + P N P YK++ L D+
Sbjct: 602 LQSI---SPKNFKVKMIMKTSVLLSWEF--PDNYNSP-TPYKIQYNGLTLDV 647
Score = 76.2 bits (179), Expect = 4e-13
Identities = 55/207 (26%), Positives = 103/207 (49%), Gaps = 12/207 (5%)
Query: 417 EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENK 476
E V + + +P+ AP +T++ +TW+ + + + +I ++ K +
Sbjct: 309 EAVAQITVKSLPK-APGTPMVTENTATSITITWD--SGNPDPVSYYVIEYKSKSQDGPYQ 365
Query: 477 EEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
+E I TT ++ I GL P++ Y + V A NS G+GP SE + RT +AP +PP
Sbjct: 366 IKEDI-----TTTRYS-IGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPR 419
Query: 537 SVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYI 596
+V TT+ V W +P + GY+V + ++ + N ++ L +
Sbjct: 420 NVQARMLSATTMIVQWE--EPVEPNGLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTV 476
Query: 597 SNIIPGKSYNLRVLAYSNGGDGRMSSP 623
+++ ++Y +RVLA+++ GDG +S P
Sbjct: 477 GSLLEDETYTVRVLAFTSVGDGPLSDP 503
Score = 67.7 bits (158), Expect = 1e-10
Identities = 73/280 (26%), Positives = 122/280 (43%), Gaps = 26/280 (9%)
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+TITW S P +Y I ++ + +Q +K+ +I T I + Y
Sbjct: 336 ITITWD----SGNPDPVSYYVIEYKSKSQDGPYQ---IKE--DITTTRYSIGGLSPNSEY 386
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NPIDQSRERL 459
++ V A N IG GP SE V + E P P+ V AR ++T + V W P++ +
Sbjct: 387 EIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVEPN---- 442
Query: 460 RGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVG-LQPDTYYYVKVMAFNSAGEGPE 518
G + G+R+ Y+ E + + + VG L D Y V+V+AF S G+GP
Sbjct: 443 -GLIRGYRV-YYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 500
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDM 578
S+ +T + P + P ++ A T++ + W P +E ++ Y++ E D
Sbjct: 501 SDPIQVKTQQGVPGQ-PMNLRAEARSETSITLSW---SPPRQES-IIKYELLFREGDHGR 555
Query: 579 STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
T P + + ++ P Y R+ A S G G
Sbjct: 556 EVGR-TFDPTTSYV---VEDLKPNTEYAFRLAARSPQGLG 591
Score = 56.0 bits (129), Expect = 4e-07
Identities = 60/202 (29%), Positives = 86/202 (42%), Gaps = 24/202 (11%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT----ENGN 81
P F K P + G G + C+ PKP TW K + + +RF T E+
Sbjct: 33 PRFIKEPKD--QIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNS--QRFETIEFDESAG 88
Query: 82 LIIR-QLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP-----PRI-TAQV 132
++R Q R DE VY CVA+N G +L VLR + P P++ +
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVER 148
Query: 133 NSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVG 191
+ C A +P D W + L + S+ N RIK + G L I + +D G
Sbjct: 149 TRTATMLCAASGNP--DPEITWFKDFLPVDPSAS---NGRIKQLRSGALQIESSEETDQG 203
Query: 192 DYECVVKSAIG-RISSHVQLRI 212
YECV ++ G R SS L +
Sbjct: 204 KYECVATNSAGVRYSSPANLYV 225
Score = 31.9 bits (69), Expect = 7.6
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 5/105 (4%)
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
PRF+++ +I F+ C A DP WN G ++ +S + + G
Sbjct: 33 PRFIKEPKDQIGVSGRVASFV-CQATGDP--KPRVTWNKKGKKV-NSQRFETIEFDESAG 88
Query: 178 GELTIYNVSLS-DVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L I + D YECV ++++G I+ H +L + P G
Sbjct: 89 AVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSG 133
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 99.5 bits (237), Expect = 3e-20
Identities = 70/221 (31%), Positives = 101/221 (45%), Gaps = 13/221 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS---LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
Y C A N L + SSA+L +LS + P F P+ ++ E G T KC
Sbjct: 8113 YNCSASNPLGTASSSAKL-ILSEHEVPPFFDLKPVSVDLALGESG--TFKCHVTGTAPIK 8169
Query: 59 FTWKKDNIVIGAGG--KRFITEN-GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
TW KDN I GG K + EN L + ++ + D G YTC A N G D L V
Sbjct: 8170 ITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQ 8229
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
PRF++KL P + + C P + LW + I++SS ++ +
Sbjct: 8230 EPPRFIKKLEPSRIVKQDEFTRYECKIGGSP--EIKVLWYKDETEIQESSKFRMSFVDSV 8287
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++N+S+ D GDY C +A G SS L+++ PP
Sbjct: 8288 --AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326
Score = 92.7 bits (220), Expect = 4e-18
Identities = 65/220 (29%), Positives = 93/220 (42%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N L + SSA+L K P F P+ ++ E + +C A
Sbjct: 7172 YSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESAD--FECHVTGAQPMRI 7229
Query: 60 TWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW KDN I GG IT GN L I ++ + D G YTC A N G D +L V
Sbjct: 7230 TWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE 7289
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P+F++KL A+ + L C P + ++ N + L ++ + +
Sbjct: 7290 PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL- 7348
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
LTI S D GDY C + +G S L ++ PP
Sbjct: 7349 ---LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 7385
Score = 85.4 bits (202), Expect = 6e-16
Identities = 59/219 (26%), Positives = 92/219 (42%), Gaps = 11/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+A N+ + +A L V + P+F P L T+ + C P
Sbjct: 4453 YTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFI--CTVTGTPVIETI 4510
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD + I++ N I +LS D GVY+C A N++G D + LI++
Sbjct: 4511 WQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDK 4570
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+++L P + + +N V L C D D W+ +G ++ D + KI
Sbjct: 4571 PHFIKELEP-VQSAINKKVHLECQVDED--RKVTVTWSKDGQKLPPGKDYKICFEDKI-- 4625
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I L D G Y C + G S + + PP
Sbjct: 4626 ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP 4664
Score = 81.4 bits (192), Expect = 9e-15
Identities = 59/218 (27%), Positives = 95/218 (43%), Gaps = 10/218 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N + SAQL V P F K LE +G ++ L+CK +P+ +W
Sbjct: 7268 YTCQATNDVGKDMCSAQLSVKE-PPKFVKK-LEASKVAKQGESIQLECKISGSPEIKVSW 7325
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+++ + K FI L I + S +D G Y C A N G D S + ++AP
Sbjct: 7326 FRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG-DASCSTALTVKAP 7384
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ P + A S V L C P + +W + ++++S + K
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEV--VWVKDRKQVRNSKKFKITS--KHFDT 7440
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+ SDVG+Y C + +G + ++ + PP
Sbjct: 7441 SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 7478
Score = 81.4 bits (192), Expect = 9e-15
Identities = 64/224 (28%), Positives = 98/224 (43%), Gaps = 20/224 (8%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y E +N + +A L+V ++ PSF + L+ ET G G +V ++CK +P +
Sbjct: 8582 VYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRK-LK-ETNGLSGSSVVMECKVYGSPPIS 8639
Query: 59 FTWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
+W + I +G K T N L + L D G YTC+A N G+DE L V
Sbjct: 8640 VSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVR 8699
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F++K P +V F P + W K SS+L R +
Sbjct: 8700 EPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPF---SVSW------FKGSSELVPGDRCNV 8750
Query: 176 ----DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL +++V S G+Y C+V + G+ S L I+ P
Sbjct: 8751 SLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 8794
Score = 80.6 bits (190), Expect = 2e-14
Identities = 61/221 (27%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSE-GGNVTLKCKPEAAPKPTF 59
+Y C+A N+ A A+L ++ KP F K ELE S V L+C+ + K T
Sbjct: 4547 VYSCKASNKFGADICQAELIIID-KPHFIK---ELEPVQSAINKKVHLECQVDEDRKVTV 4602
Query: 60 TWKKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW KD + G F + L I D G Y C A N+ G+ + V
Sbjct: 4603 TWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 4662
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY-VNKRIKI 175
P F++K+ P LHC P++ + N+ L ++ +Y VN +
Sbjct: 4663 PPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 4722
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D I +V + D G Y C + +G S ++ I+ PP
Sbjct: 4723 D-----ITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 4758
Score = 77.4 bits (182), Expect = 2e-13
Identities = 78/368 (21%), Positives = 149/368 (40%), Gaps = 29/368 (7%)
Query: 162 KDSSDLYVNKRIKIDG----GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG 217
KD +L N + ++ + I + + G YE +++A+G S+ ++++I PG
Sbjct: 27835 KDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPG 27894
Query: 218 PPGG-VQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVD 275
PPGG ++ + +TL W ++ G IT Y++ R W ++SE++ +
Sbjct: 27895 PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECI--- 27951
Query: 276 RYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGG 335
+T ++ Y FR++A+N G G+P + + P
Sbjct: 27952 --------ITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTK 28003
Query: 336 GKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTY 395
+T+ W+ P + G I +R+ + + +L + + V ++
Sbjct: 28004 ITKNSMTVVWS-RPIA-DGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTEN- 28060
Query: 396 FYTPYDVKVQAFNDIGPGPESEVVTIYSAEDM--PQVAPQLVSARSFNSTALNVTWN-PI 452
+ Y +V A N G GP SE Y A D P P + +++ + W+ P+
Sbjct: 28061 --SDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPV 28118
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
+ G ++ R + E +E + ++ L+P YY +V A N
Sbjct: 28119 YDGGSAVTGYVVEIR----QGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNC 28174
Query: 513 AGEGPESE 520
AG+G E
Sbjct: 28175 AGQGEPIE 28182
Score = 76.6 bits (180), Expect = 3e-13
Identities = 96/414 (23%), Positives = 157/414 (37%), Gaps = 40/414 (9%)
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYL--------WNHNGLRIKDSSDLYVNKRI 173
E +PPRI V L A + LD W +G +K + + + +
Sbjct: 20216 ENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR 20275
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVT 233
+ L +++V+ D GDY +++ G S+ ++L++ PGPP V+I +
Sbjct: 20276 NLC--TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM 20333
Query: 234 LEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPW 292
L W G IT Y++ R W +S +P + + K L+
Sbjct: 20334 LSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVP----ITSCSVEK-------LIEG 20382
Query: 293 AIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG--GGKTGD-LTITWTPLP 349
Y+FRI A N G G P P + + PY+ P T D +T++W P P
Sbjct: 20383 HEYQFRICAENKYGVGDPVFTEPAIAKN---PYDPPGRCDPPVISNITKDHMTVSWKP-P 20438
Query: 350 TSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFND 409
P Y + +R V + + K I + + T Y+ +V A N
Sbjct: 20439 ADDGGSPITGY-LLEKRETQAVNWTKVNRKP---IIERTLKATGLQEGTEYEFRVTAINK 20494
Query: 410 IGPGPESEVVTIYSAED--MPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGH 466
GPG S+ A D P P ++++++W P + G L+
Sbjct: 20495 AGPGKPSDASKAAYARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLV-- 20552
Query: 467 RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+K +N + + TR + GL DT Y +V A N G S+
Sbjct: 20553 EVKRADSDNWVRCNLPQNLQKTR--FEVTGLMEDTQYQFRVYAVNKIGYSDPSD 20604
Score = 75.8 bits (178), Expect = 5e-13
Identities = 62/218 (28%), Positives = 102/218 (46%), Gaps = 12/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N ++ SS L+V P F+K P +ET +G +V L+C+ + P +W
Sbjct: 8303 YTCEAHNAAGSASSSTSLKVKE-PPIFRKKPHPIETL--KGADVHLECELQGTPPFHVSW 8359
Query: 62 KKDNIVIGAGGK-RFITENGNLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD + +G K + ++EN I L+ D D G Y C A N G+D G + + P
Sbjct: 8360 YKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 8419
Query: 119 RFLEKLPPRITAQVNSVVFLHCNAD-VDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
RF++KL I+ V V L + +PI + + G +++S +++++ I
Sbjct: 8420 RFVKKLSD-ISTVVGKEVQLQTTIEGAEPI--SVVWFKDKGEIVRESDNIWISYSENI-- 8474
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L V ++ G Y C +K+ G L + P
Sbjct: 8475 ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP 8512
Score = 75.8 bits (178), Expect = 5e-13
Identities = 81/344 (23%), Positives = 125/344 (36%), Gaps = 30/344 (8%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
LTI + D G+Y + G HV++ + PGPPG V+I + TL WT
Sbjct: 21364 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPP 21423
Query: 240 -NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
G PI Y+L R W V+SE+I + V+T L+ Y FR
Sbjct: 21424 LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRH-----------VATKLIQGNEYIFR 21472
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW-TPLPTSLQNGPG 357
+ A+N G G+P P P P T++W P+ G
Sbjct: 21473 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 21532
Query: 358 IHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESE 417
H + RR + + + ++ V + + Y+ +V A N G GP SE
Sbjct: 21533 YHVE---RREKKSLRWVRAIKTPVSDLRCKVTGLQEG---STYEFRVSAENRAGIGPPSE 21586
Query: 418 VVTIYSAED--MPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQE 474
+D P P + ++ W P + G ++ H Q+
Sbjct: 21587 ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH------QK 21640
Query: 475 NKEEECIYYLSRTTRNWA--LIVGLQPDTYYYVKVMAFNSAGEG 516
+E I + T ++ LQ Y ++ A N AG G
Sbjct: 21641 VGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 21684
Score = 73.7 bits (173), Expect = 2e-12
Identities = 56/219 (25%), Positives = 95/219 (43%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ +S SA + V PSF K ++ G + L CK + +P TW
Sbjct: 4641 YVCTASNEAGSSSCSATVTVRE-PPSFVKK-VDPSYLMLPGESARLHCKLKGSPVIQVTW 4698
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K+N + F+ L I + +D G Y+C A N G+D +++ P
Sbjct: 4699 FKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 4758
Query: 119 RFLEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
F++ L P I N++ L C + ++ + +R L+ K +
Sbjct: 4759 SFIKTLEPADIVRGTNAL--LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVC-- 4814
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I++ + +DVG+YECVV + +G+ ++ PP
Sbjct: 4815 --LEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPP 4851
Score = 72.9 bits (171), Expect = 3e-12
Identities = 67/250 (26%), Positives = 103/250 (41%), Gaps = 11/250 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N + + S A L V P F K P + + G + T +C+ PK +W
Sbjct: 5765 YICQLSNDVGTATSKATLFVKE-PPQFIKKPSPVLVLRN-GQSTTFECQITGTPKIRVSW 5822
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
D I A K I+ L Q+S ++ G Y C A+N GT L V P
Sbjct: 5823 YLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 5882
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F+ +L P + S V L C P + W N I+ S + R+ +
Sbjct: 5883 TFIRELKP-VEVVKYSDVELECEVTGTPPFEVT--WLKNNREIRSSKKYTLTDRVSV--F 5937
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ-ILGIQRSSVTLEWT 237
L I SD G+Y+C+V + G S ++ ++ PP ++ + +SS T + T
Sbjct: 5938 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQST 5997
Query: 238 DSNSNGRPIT 247
+ S IT
Sbjct: 5998 VAGSPPISIT 6007
Score = 72.1 bits (169), Expect = 6e-12
Identities = 88/361 (24%), Positives = 142/361 (39%), Gaps = 25/361 (6%)
Query: 166 DLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP-GGVQI 224
D +VNK + D L I SD G Y + +G S ++L + G PGPP G ++
Sbjct: 17094 DTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKF 17153
Query: 225 LGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRA 283
+ +TL W + G IT Y++ R TW +S K
Sbjct: 17154 ESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSE------------PKEC 17201
Query: 284 TVS-TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLT 342
T + LL Y FRI A N G G+P P+ + + AP + +T
Sbjct: 17202 TYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMT 17261
Query: 343 ITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH-ISSTYFYTPYD 401
+ W P P Y + + S+ ++ + + V + ++ + Y
Sbjct: 17262 VNWEE-PEYDGGSPVTGYWLEMKDTTSK-RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQ 17319
Query: 402 VKVQAFNDIGPGPESEVVTIYSAED-MPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+V A N G GP S +A D + P + ++ ++ W+P +
Sbjct: 17320 FRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSP---PLKDGG 17376
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV-GLQPDTYYYVKVMAFNSAGEGPES 519
K+ G+ ++Y K+E K EE + R L+V GL+ +Y +V A N AG G
Sbjct: 17377 SKVTGYIVEY-KEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPG 17434
Query: 520 E 520
E
Sbjct: 17435 E 17435
Score = 70.5 bits (165), Expect = 2e-11
Identities = 134/597 (22%), Positives = 223/597 (37%), Gaps = 48/597 (8%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFITEN----GNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
P PT W K+ + R + +N LII+ R D G Y A N G+ +
Sbjct: 16059 PVPTKVWTKEEGELDKD--RVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAA 16116
Query: 111 RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
R+ V P + L P +T + ++ D T ++ ++
Sbjct: 16117 RVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIET 16176
Query: 171 KRIKIDGGELTI---YNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
+R K D L Y + + C IG I + L GPP P +
Sbjct: 16177 ERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL---GPPTSPERLTYTER 16233
Query: 228 QRSSVTLEWTDSNSNG-RPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVS 286
+S++TL+W + SNG PI GY++ R H + P+ V++ + +
Sbjct: 16234 TKSTITLDWKEPRSNGGSPIQGYIIEKRRH----------DKPDFERVNKRLCPTTSFLV 16283
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
L +YEFR++A+N +G +PS P + P +S G
Sbjct: 16284 ENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPV 16343
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVE--FQSLLLKK---YGNIGTYVVHISSTYFYTPYD 401
+P + P KI W +N + +E +L + K + + I
Sbjct: 16344 HIPADVTGLP--MPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT 16401
Query: 402 VKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN-PIDQSRERLR 460
V A N +G + V +Y D P P+ ++ + + +TW+ P+D +
Sbjct: 16402 YTVTASNRLGSVFRNVHVEVY---DRPS-PPRNLAVTDIKAESCYLTWDAPLDNGGSEIT 16457
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPE-- 518
+I R K+ EE + + W LI P+ Y +V A N G E
Sbjct: 16458 HYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI----PNGQYEFRVRAVNKYGISDECK 16513
Query: 519 SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQD- 577
S++ + + + P PP V A ++ V W N P+ GY + E
Sbjct: 16514 SDKVVIQDPYRLP-GPPGKPKVLARTKGSMLVSWT-PPLDNGGSPITGYWLEKREEGSPY 16571
Query: 578 ---MSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAFQIGD 631
+S A T V ++ +E + ++ G Y R +A + G G S P+ GD
Sbjct: 16572 WSRVSRAPITKVGLK-GVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD 16627
Score = 69.7 bits (163), Expect = 3e-11
Identities = 57/222 (25%), Positives = 94/222 (42%), Gaps = 18/222 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C N + S S + +++ P F K LE G + L+CK +P+ W
Sbjct: 6327 YTCHVTNDV-GSDSCTTMLLVTEPPKFVKK-LEASKIVKAGDSSRLECKIAGSPEIRVVW 6384
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
++ + A K FI + + LS +D G + C A+N G+ ++IV P
Sbjct: 6385 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 6444
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F PP + N+ V L C P + +W KD L +K+ KI
Sbjct: 6445 VF-SSFPPIVETLKNAEVSLECELSGTPPFEV--VW------YKDKRQLRSSKKYKIASK 6495
Query: 179 E----LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I NV SD+G+Y C ++ +G + ++++ PP
Sbjct: 6496 NFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 6537
Score = 69.7 bits (163), Expect = 3e-11
Identities = 67/242 (27%), Positives = 99/242 (40%), Gaps = 16/242 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC+A N + + + L P F K ++ T G V L+ E A + W
Sbjct: 8396 YQCKATNDVGSDTCVGSI-ALKAPPRFVKKLSDISTV--VGKEVQLQTTIEGAEPISVVW 8452
Query: 62 KKDN-IVIGAGGKRFITENGNLIIRQLSRDDE---GVYTCVAKNQYGTDESRGRLIVLRA 117
KD ++ +I+ + N+ Q SR + G YTC KN G E L VL
Sbjct: 8453 FKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEP 8512
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+EK P I L C P L T W +G + + ++ K+ G
Sbjct: 8513 ATIVEK-PESIKVTTGDTCTLECTVAGTPELSTK--WFKDGKELTSDNKYKISFFNKVSG 8569
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL----GIQRSSVT 233
L I NV+ SD G Y V++ +G+ S L++ PP + L G+ SSV
Sbjct: 8570 --LKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVV 8627
Query: 234 LE 235
+E
Sbjct: 8628 ME 8629
Score = 69.3 bits (162), Expect = 4e-11
Identities = 60/219 (27%), Positives = 97/219 (44%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y + +N + S +A + V ++ PSF + L+ T G G + L+CK + +
Sbjct: 6701 YTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRR-LK-NTGGVLGASCILECKVAGSSPISV 6758
Query: 60 TW--KKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W +K IV GA + ++N L + L D G YTCVA N G+DE R L V
Sbjct: 6759 AWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 6818
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+++ P +V F P + L D ++Y +
Sbjct: 6819 PPSFVKEPEPLEVLPGKNVTFTSVIRGTPP-FKVNWFRGARELVKGDRCNIYFEDTV--- 6874
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL ++N+ +S G+Y CVV + G+ S +L ++ P
Sbjct: 6875 -AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 6912
Score = 69.3 bits (162), Expect = 4e-11
Identities = 86/380 (22%), Positives = 150/380 (39%), Gaps = 43/380 (11%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
W +G+ I+ ++ + + L + + + G Y K+A G + ++++++
Sbjct: 28919 WFKDGVEIEKRMNMEITD--VLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28976
Query: 214 GPPGPP-GGVQILGIQRSSVTLEWTDSNSNG-RPITGYMLTGRTHWNSTWYVISENIPNV 271
PG G ++ I +TL W ++G PIT Y++ R W +I +
Sbjct: 28977 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--- 29033
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSP-----QFSTSGDKPYE 326
E Y K L+ Y+FR+ A+N G G+P P Q++
Sbjct: 29034 -EAQSYTAIK-------LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP 29085
Query: 327 APANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGT 386
P+N++G +T+TW P S G I I RR + ++ K+ I
Sbjct: 29086 EPSNITG-----NSITLTWA-RPES-DGGSEIQQYILERREKKSTRWVKVISKR--PISE 29136
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED--MPQVAPQLVSARSFNSTA 444
++ Y+ V A N G GP S + + + P P +V + T
Sbjct: 29137 TRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTT 29196
Query: 445 LNVTWN-PIDQSRERLRGKLI---GHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPD 500
+++ W+ P+ + G +I L W + N E C+ +R T + LQ
Sbjct: 29197 VSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVN-AEACV--KTRYT-----VTDLQAG 29248
Query: 501 TYYYVKVMAFNSAGEGPESE 520
Y +V A N AG+G E
Sbjct: 29249 EEYKFRVSAINGAGKGDSCE 29268
Score = 68.9 bits (161), Expect = 5e-11
Identities = 105/452 (23%), Positives = 167/452 (36%), Gaps = 36/452 (7%)
Query: 170 NKRIKIDG----GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL 225
+KRI I+ +TI + SD G Y + GR ++ V++ + PGPP I
Sbjct: 14661 DKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDIT 14720
Query: 226 GIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRAT 284
+ S L W + G IT Y++ R + W+ +S + + N +
Sbjct: 14721 DVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDT------NFK---- 14770
Query: 285 VSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTIT 344
+T L+P Y FR+ A N+ G G+P SP + P P + +T+T
Sbjct: 14771 -ATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLT 14829
Query: 345 WTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKV 404
W P P Y + R + + K TY + Y +V
Sbjct: 14830 WCE-PDDDGGSPITGYWV--ERLDPDTDKWVRCNKMPVKDTTY--RVKGLTNKKKYRFRV 14884
Query: 405 QAFNDIGPGPES---EVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRG 461
A N GPG S E + I D P P + + T++ + W +
Sbjct: 14885 LAENLAGPGKPSKSTEPILIKDPID-PPWPPGKPTVKDVGKTSVRLNWTKPEHDG---GA 14940
Query: 462 KLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESER 521
K+ + ++ K E + TT++ L+ GL Y +V A N AGE SE
Sbjct: 14941 KIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRAVNKAGESEPSEP 14998
Query: 522 YLERTFRKA--PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMS 579
R+ P PP + V T + W V + P+ Y V ++ +
Sbjct: 14999 SDPVLCREKLYPPSPPRWLEVINITKNTADLKWT-VPEKDGGSPITNYIVEKRDVRRKGW 15057
Query: 580 TANDTIVPIEHKLEAYISNIIPGKSYNLRVLA 611
DT V + ++ + G Y RV A
Sbjct: 15058 QTVDTTV---KDTKCTVTPLTEGSLYVFRVAA 15086
Score = 67.3 bits (157), Expect = 2e-10
Identities = 49/181 (27%), Positives = 81/181 (44%), Gaps = 8/181 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT--ENGNLI-IRQLSRDDEGVYTCV 98
G + L+ P + +W KD +I + IT E ++ I + + +D Y+C+
Sbjct: 7868 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 7927
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N+ G D + VL P F+E L + A + L C D P + ++ H
Sbjct: 7928 IENEAGQDICEALVSVLEPPYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISWYKEHTK 7986
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
LR S+ Y + K + L I V SDVG+Y C +++G ++S L I+ P
Sbjct: 7987 LR---SAPAY-KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLP 8042
Query: 219 P 219
P
Sbjct: 8043 P 8043
Score = 67.3 bits (157), Expect = 2e-10
Identities = 99/408 (24%), Positives = 149/408 (36%), Gaps = 40/408 (9%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
W +G IK +D + LTI N D G+Y+ V +A G + V L +
Sbjct: 18471 WTTDGSEIK--TDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVL 18528
Query: 214 GPPGPP-GGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
PGPP G + IL + +T+ W + G P+ Y++ + TW V+S
Sbjct: 18529 DVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSS----- 18583
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANV 331
K L Y FR++A N +G G P +P + P P
Sbjct: 18584 ------GSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 18637
Query: 332 SGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHI 391
T++WT LP S P Y + R EV + + + K I +
Sbjct: 18638 VVTDITENAATVSWT-LPKSDGGSPITGYYMERR----EVTGKWVRVNK-TPIADLKFRV 18691
Query: 392 SSTYFYTPYDVKVQAFNDIG---PGPESEVVTIYS--AEDMPQVAPQLVSARSFNSTALN 446
+ Y Y+ +V A N G P P S+ + P + P+L TA
Sbjct: 18692 TGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKD--KSRETADL 18749
Query: 447 VTWNPIDQSRERLRGKLIGHR---LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYY 503
V P+ + G ++ + W + NK+E R + GL Y
Sbjct: 18750 VWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQCAFR-------VPGLIEGNEY 18802
Query: 504 YVKVMAFNSAGEGPESERYLERTFRKAPQKPP-ASVNVWAHDPTTLRV 550
++ A N GEG E E K PP ++V D T+RV
Sbjct: 18803 RFRIKAANIVGEG-EPRELAESVIAKDILHPPEVELDVTCRDVITVRV 18849
Score = 66.9 bits (156), Expect = 2e-10
Identities = 95/468 (20%), Positives = 182/468 (38%), Gaps = 40/468 (8%)
Query: 61 WKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W ++N+V+ G K + G L I + D+G Y +AK++ E+R +L + A
Sbjct: 13871 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDK----EARAKLELAAA 13926
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P+ ++ + V + + D P + + + L K + D +
Sbjct: 13927 PK-IKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK-TIDTTAEQT----- 13979
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWT 237
I D G Y+ V+++ G+ + L++ PGP +++ V+L W
Sbjct: 13980 -SFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWE 14038
Query: 238 DS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYE 296
+ G I GY++ R TW V+ DR + TV+ Y
Sbjct: 14039 EPLTDGGSKIIGYVVERRDIKRKTW---------VLATDRAESCE-FTVTGLQKGGVEYL 14088
Query: 297 FRIQAINILGPGQP-SAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
FR+ A N +G G+P +P + S P NV+ +++TW P G
Sbjct: 14089 FRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWE--PPEYDGG 14146
Query: 356 PGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPG-P 414
I + R+ + + + + + + ++ V + Y +V+A N IG G P
Sbjct: 14147 AEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEG---QEYSFRVRAQNRIGVGKP 14203
Query: 415 ESEVVTIYSAEDMPQVAPQL-VSARSFNSTALNVTWN-PIDQSRERLRGKLIGHRLKYWK 472
+ + A+ + + +P + +++ +++ + W P+ + G +I
Sbjct: 14204 SAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIER-----C 14258
Query: 473 QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
+E K+ + + GL+ Y +V A N AG SE
Sbjct: 14259 EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 14306
Score = 66.9 bits (156), Expect = 2e-10
Identities = 92/431 (21%), Positives = 157/431 (36%), Gaps = 34/431 (7%)
Query: 129 TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE----LTIYN 184
T +V + +H ADV + W+ N I+ +D + ++ E L+I
Sbjct: 16334 TIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPK 16393
Query: 185 VSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW-TDSNSNG 243
D G Y + +G + +V + + P PP + + I+ S L W ++ G
Sbjct: 16394 AVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 16453
Query: 244 RPITGYMLTGR--THWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQA 301
IT Y++ R + + W E + N RY K L+P YEFR++A
Sbjct: 16454 SEITHYVIDKRDASRKKAEW----EEVTNTAVEKRYGIWK-------LIPNGQYEFRVRA 16502
Query: 302 INILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYK 361
+N G + P G + ++WTP P P Y
Sbjct: 16503 VNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTP-PLDNGGSPITGYW 16561
Query: 362 IFWRRNGSEV--EFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVV 419
+ R GS + K G G ++ Y + A N G GP SE
Sbjct: 16562 LEKREEGSPYWSRVSRAPITKVGLKGV-EFNVPRLLEGVKYQFRAMAINAAGIGPPSEPS 16620
Query: 420 TIYSAED--MPQVAPQLVSARSFNSTALNVTWN-PIDQSRERLRGKLIGHR---LKYWKQ 473
A D P P + +++++ W P ++G ++ + WK+
Sbjct: 16621 DPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKR 16680
Query: 474 ENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQK 533
N+ ++ I T ++ L+ Y +V A N AGE S+ E ++
Sbjct: 16681 VNEPDKLI------TTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEE 16734
Query: 534 PPASVNVWAHD 544
P +++ A D
Sbjct: 16735 PEVFIDIGAQD 16745
Score = 66.1 bits (154), Expect = 4e-10
Identities = 103/414 (24%), Positives = 155/414 (37%), Gaps = 39/414 (9%)
Query: 41 EGGNVTLKCKPEAAPKPTFTW------KKDN----IVIGAGGKRFITENGNLIIRQLSRD 90
EG NV + K + P PT TW K DN + K + + L+I Q R
Sbjct: 17057 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 17116
Query: 91 DEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDT 150
D G+YT A N GT RL VL P PP + SV P D
Sbjct: 17117 DTGLYTITAVNNLGTASKEMRLNVLGRPG-----PPVGPIKFESVSADQMTLSWFPPKDD 17171
Query: 151 AYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV----KSAIGR-IS 205
N + K ++ + + E T L + +Y + K IG +
Sbjct: 17172 GGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD 17231
Query: 206 SHVQL--RIEGPPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWY 262
S + + PG P + + R+S+T+ W + G P+TGY L + + W
Sbjct: 17232 SEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWK 17291
Query: 263 VISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS-PQFSTSG 321
++ + M + + T L+ + Y+FR+ AIN G G S PS P +
Sbjct: 17292 RVNRDPIKAMTLGV------SYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 17345
Query: 322 DKPYEAP-ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKK 380
P P V+ + DL W+P P Y + ++ G E E++ K+
Sbjct: 17346 IAPPGPPFPKVTDWTKSSADL--EWSP-PLKDGGSKVTGYIVEYKEEGKE-EWEKGKDKE 17401
Query: 381 YGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQL 434
V + F Y +V A N G G EV + +D V+P L
Sbjct: 17402 VRGTKLVVTGLKEGAF---YKFRVSAVNIAGIGEPGEVTDVIEMKDR-LVSPDL 17451
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 94/220 (42%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL--KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y E +N + S A++ VL L PSF K ++++ +G + L+C + +
Sbjct: 5576 YTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSI--KGSFIDLECIVAGSHPISI 5633
Query: 60 TWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD+ I A K + + N L I QL D G YTC A N+ G ++ G L V
Sbjct: 5634 QWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 5693
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+EK P+ + VN + A V W + + + V K
Sbjct: 5694 PPYFVEK--PQ-SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWK--DDT 5748
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ +D G Y C + + +G +S L ++ PP
Sbjct: 5749 STSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 5788
Score = 65.3 bits (152), Expect = 7e-10
Identities = 125/587 (21%), Positives = 217/587 (36%), Gaps = 47/587 (8%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAK 100
G + L + P P TWKK++ + +T G+ L IR + +D G+Y+ +
Sbjct: 18160 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 18219
Query: 101 NQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILD------TAYLW 154
N G+ +++VL P PPR +V+ + C LD T Y+
Sbjct: 18220 NPAGSKTVSVKVLVLDKPG-----PPR-DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVV 18273
Query: 155 NHNGLRIKDSSDLYVNKRIKID-GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ-LRI 212
+ S L + K L N L V + ++ L
Sbjct: 18274 ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDP 18333
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
PPGPP + + + ++ V+L W G PITGY++ + W + + + N+
Sbjct: 18334 LHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDW-IKFKTVTNL 18392
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANV 331
V T L Y FR++A NI+G G P P P +V
Sbjct: 18393 -----------ECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDV 18441
Query: 332 SGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHI 391
G T P ++ P K W +GSE++ + N + V+ I
Sbjct: 18442 KLIEGLVVKAGTT-VRFPAIIRGVPVPTAK--WTTDGSEIKTDEHYTVETDNFSS-VLTI 18497
Query: 392 SSTYFYTPYDVKVQAFNDIGPGPESEVVTIY-SAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ + ++ N G S+ V ++ + D+P ++ + ++W
Sbjct: 18498 KNCLRRDTGEYQITVSNAAG----SKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQ 18553
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
P ++ +I + ++ KQ+ +++ S +++ I LQ Y +V A
Sbjct: 18554 P---PKDDGGSPVINYIVE--KQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAE 18608
Query: 511 NSAGEGPESERYLERTFRK-APQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
N G GP + K +P PP V V W + ++ P+ GY +
Sbjct: 18609 NKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWT-LPKSDGGSPITGYYM 18667
Query: 570 RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG 616
E+ N T PI L+ ++ + G +Y RV A + G
Sbjct: 18668 ERREVTGKWVRVNKT--PIA-DLKFRVTGLYEGNTYEFRVFAENLAG 18711
Score = 64.5 bits (150), Expect = 1e-09
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 15/219 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKH--PLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y CEA+N + S +L+V P+F + P+E+ Y +V L+C+ P
Sbjct: 5859 YVCEARNDAGTASCSIELKVKE-PPTFIRELKPVEVVKYS----DVELECEVTGTPPFEV 5913
Query: 60 TWKKDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TW K+N I + K +T+ NL I + D G Y C+ N+ G+ R+ +
Sbjct: 5914 TWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE 5973
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F++K+ T +S F A PI T W + + + ++Y++ +
Sbjct: 5974 PPSFIKKIENTTTVLKSSATFQSTVAGSPPISIT---WLKDDQILDEDDNVYISFVDSV- 6029
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L I +V G Y C K+ G + L ++ P
Sbjct: 6030 -ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 6067
Score = 63.7 bits (148), Expect = 2e-09
Identities = 52/223 (23%), Positives = 91/223 (40%), Gaps = 12/223 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N+ A + VL +P + PLE G TL+CK + P+ +W
Sbjct: 7924 YSCLIENEAGQDICEALVSVL--EPPYFIEPLE-HVEAVIGEPATLQCKVDGTPEIRISW 7980
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL--R 116
K++ + + +F +L+I ++ D G Y+C A N G S L++ +
Sbjct: 7981 YKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK 8040
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F + + + V C + L + W +G+ +KD ++L + +
Sbjct: 8041 LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVS--WYKDGVLLKDDANLQTSFVHNV- 8097
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I S +G Y C + +G SS +L + PP
Sbjct: 8098 -ATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 8139
Score = 63.3 bits (147), Expect = 3e-09
Identities = 96/457 (21%), Positives = 175/457 (38%), Gaps = 41/457 (8%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWT-D 238
L I N + D G Y + + G + V +R+ PGP +++ + ++S + W
Sbjct: 19590 LVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPP 19649
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N G +T Y++ R TW ++ + +K + T L+P Y FR
Sbjct: 19650 ENDGGSQVTHYIVEKREADRKTWSTVTPEV-----------KKTSFHVTNLVPGNEYYFR 19698
Query: 299 IQAINILGPGQPS-APSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPG 357
+ A+N GPG P+ P P ++ + P + T+ W LP G
Sbjct: 19699 VTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAW--LPPLRDGGAK 19756
Query: 358 IHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESE 417
I I R E E + +Y + + ++ Y +V A N +G E
Sbjct: 19757 IDGYITSYR---EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPRE 19813
Query: 418 VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKE 477
+Y A++ QL+ + + + + + GK H WK+ E
Sbjct: 19814 AEGVYEAKE------QLLPPKILMPEQITIKAGKKLRIEAHVYGK--PHPTCKWKKGEDE 19865
Query: 478 EECIYYLS--RTTRNWALIVG--LQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQK 533
+L+ + + LI+ + D+ YY + A NS+G + ++ AP
Sbjct: 19866 VVTSSHLAVHKADSSSILIIKDVTRKDSGYY-SLTAENSSGTDTQK---IKVVVMDAPGP 19921
Query: 534 PPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKL 592
P ++ D + W ++ + + Y V ++ + D TA ++ K
Sbjct: 19922 PQPPFDISDIDADACSLSW-HIPLEDGGSNITNYIVEKCDVSRGDWVTALASVT----KT 19976
Query: 593 EAYISNIIPGKSYNLRVLAYSNGGDGR-MSSPTIAFQ 628
+ +IPG+ Y RV A + G ++SP + Q
Sbjct: 19977 SCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQ 20013
Score = 62.9 bits (146), Expect = 4e-09
Identities = 54/204 (26%), Positives = 81/204 (39%), Gaps = 10/204 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
+ C A N + + SS L ++ PSF P + G V LK + + T W
Sbjct: 5110 FTCRATNSVGSKDSSGAL-IVQEPPSFVTKPGSKDVL--PGSAVCLKSTFQGSTPLTIRW 5166
Query: 62 KKDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K N + +GG +IT+ +L + + D G YTC N G E L V
Sbjct: 5167 FKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 5226
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F+EKL P + L C P + W N IK+SS ++
Sbjct: 5227 TFVEKLEPSQLLKKGDATQLACKVTGTPPIKIT--WFANDREIKESSKHRMS--FVESTA 5282
Query: 179 ELTIYNVSLSDVGDYECVVKSAIG 202
L + +V + D G+Y C ++ G
Sbjct: 5283 VLRLTDVGIEDSGEYMCEAQNEAG 5306
Score = 62.9 bits (146), Expect = 4e-09
Identities = 82/376 (21%), Positives = 150/376 (39%), Gaps = 28/376 (7%)
Query: 146 PILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRIS 205
PI D +W+ +G +++++ + + I L + + +D G Y + + G S
Sbjct: 25662 PIPDV--VWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKS 25718
Query: 206 SHVQLRIEGPPGPPGG-VQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYV 263
+ +++ PGPP G +++ G+ L W G I+ Y++ R +W
Sbjct: 25719 IPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQ 25778
Query: 264 ISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK 323
+S EV N + T LLP Y FR+ A+N G G+P P + + K
Sbjct: 25779 VST------EVQALNYKV-----TKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYK 25827
Query: 324 PYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGN 383
P P+ + +TW P G I I +R+ V + K +
Sbjct: 25828 PPGPPSTPEVSAITKDSMVVTWA-RPVD-DGGTEIEGYILEKRDKEGVRWTKCNKKTLTD 25885
Query: 384 IGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED--MPQVAPQLVSARSFN 441
+ V ++ + Y+ +V A N G G SE Y A D P P +
Sbjct: 25886 LRLRVTGLTEGH---SYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTS 25942
Query: 442 STALNVTWN-PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPD 500
+++++ W+ PI ++G ++ +K ++ C + + + L+ +
Sbjct: 25943 RSSVSLAWSKPIYDGGAPVKGYVV--EVKE-AAADEWTTCTPPTGLQGKQFT-VTKLKEN 25998
Query: 501 TYYYVKVMAFNSAGEG 516
T Y ++ A NS G G
Sbjct: 25999 TEYNFRICAINSEGVG 26014
Score = 62.5 bits (145), Expect = 5e-09
Identities = 50/222 (22%), Positives = 93/222 (41%), Gaps = 13/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN-VTLKCKPEAAPKPTFT 60
Y C N+ A +S + P+ K L Y E G + L+ P + T
Sbjct: 8772 YTCIVSNE--AGKASCTTHLYIKAPA--KFVKRLNDYSIEKGKPLILEGTFTGTPPISVT 8827
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSR---DDEGVYTCVAKNQYGTDESRGRLIVLRA 117
WKK+ I + + IT I ++ +D G Y C +N G D ++++L
Sbjct: 8828 WKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 8887
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P F+++L P + V L C P + + W +++ ++ ++ R +
Sbjct: 8888 PYFVKQLEP-VKVSVGDSASLQCQLAGTPEIGVS--WYKGDTKLRPTTTYKMHFRNNV-- 8942
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L V ++D G+Y C ++++G +S+ L ++ PP
Sbjct: 8943 ATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPP 8984
Score = 62.5 bits (145), Expect = 5e-09
Identities = 94/398 (23%), Positives = 154/398 (38%), Gaps = 32/398 (8%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVI--GAGGKRFITEN-GNLIIRQLSRDDEGVYTCV 98
G NV L P PT +WKKD ++ G K + N L + ++R D G YT
Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 20296
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
A+N G+ + +L VL +K P + ++N + +P L+ N
Sbjct: 20297 AENSSGSKSATIKLKVL------DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNY 20350
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV----KSAIGRISSHVQLRIEG 214
+ K + ++ + L + +Y+ + K +G +
Sbjct: 20351 IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKN 20410
Query: 215 PPGPPGGVQ---ILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
P PPG I I + +T+ W ++ G PITGY+L R W
Sbjct: 20411 PYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW--------- 20461
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS-APSPQFSTSGDKPYEAPA 329
+V+R +R +T L YEFR+ AIN GPG+PS A ++ P PA
Sbjct: 20462 -TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPA 20520
Query: 330 NVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV 389
++++W P P I Y + +R S+ + L + N+
Sbjct: 20521 FPKVYDTTRSSVSLSWGK-PAYDGGSPIIGYLVEVKRADSDNWVRCNLPQ---NLQKTRF 20576
Query: 390 HISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDM 427
++ T Y +V A N IG S+V + +D+
Sbjct: 20577 EVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDI 20614
Score = 62.5 bits (145), Expect = 5e-09
Identities = 97/460 (21%), Positives = 175/460 (38%), Gaps = 35/460 (7%)
Query: 84 IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLP----PRITAQVNSVVFLH 139
I L+ +E V+ A N+ G + R +L V R +E P P T V + L
Sbjct: 26282 ISGLTAGEEYVFRVAAVNEKGRSDPR-QLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340
Query: 140 CNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
+ W +G +K+++ + V+ + L+I S DVG YE V +
Sbjct: 26341 IDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS--LSIKEASKEDVGTYELCVSN 26398
Query: 200 AIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWN 258
+ G I+ + + + PGPPG ++I + S+T+ W G I+ Y++ + +
Sbjct: 26399 SAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTS 26458
Query: 259 STWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFS 318
+TW+++S+ + + + L + Y+FR+ A N G S S +
Sbjct: 26459 TTWHIVSQAV-----------ARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 26507
Query: 319 TSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLL 378
P P + +TW +P + I Y + ++ E S+L
Sbjct: 26508 EYPFSPPGPPGTPKVVHATKSTMLVTW-QVPVNDGGSRVIGYHLEYK------ERSSILW 26560
Query: 379 KKYGN--IGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVS 436
K I + +S Y+ +V A N G G S+ A D P P
Sbjct: 26561 SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARD-PCDPPGQPE 26619
Query: 437 ARSFNSTALNVTWN-PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV 495
+ ++++ W+ P ++ G ++ R + + +C Y + + +
Sbjct: 26620 VTNITRKSVSLKWSKPHYDGGAKITGYIVERR---ELPDGRWLKCNY--TNIQETYFEVT 26674
Query: 496 GLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPP 535
L D Y +V A N+A E K +PP
Sbjct: 26675 ELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPP 26714
Score = 62.1 bits (144), Expect = 6e-09
Identities = 59/221 (26%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLE-LETYGSEGGNVTLKCKPEAAPKPTFT 60
Y CEA N + +SA+L V+ K +E LE + G C+ ++AP F
Sbjct: 4358 YVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEV--ALGHLAKFTCEIQSAPNVRFQ 4415
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD---DEGVYTCVAKNQYGTDESRGRLIVLRA 117
W K I K I + + ++ R D G YTC A N+YG+ L V A
Sbjct: 4416 WFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA 4475
Query: 118 --PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P FL + P +T V C P+++T +W +G + S + ++
Sbjct: 4476 YPPTFLSR-PKSLTTFVGKAAKFICTVTGTPVIET--IWQKDGAALSPSPNWKISDAENK 4532
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
EL+ N+++ D G Y C + G +L I P
Sbjct: 4533 HILELS--NLTIQDRGVYSCKASNKFGADICQAELIIIDKP 4571
Score = 62.1 bits (144), Expect = 6e-09
Identities = 58/223 (26%), Positives = 90/223 (40%), Gaps = 15/223 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPS-FKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
Y C N A +S R+ +P+ F K L + E G ++ L+ +
Sbjct: 6890 YTCVVSNN--AGQASCTTRLFVKEPAAFLKR---LSDHSVEPGKSIILESTYTGTLPISV 6944
Query: 60 TWKKDNIVIGAGGK-RFITENGNLIIRQLS--RDDEGVYTCVAKNQYGTDESRGRLIVLR 116
TWKKD I K +T I+ L+ + D G Y+C +N+ G D + L
Sbjct: 6945 TWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE 7004
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+ +L P + A V V L C P + ++ LR Y +
Sbjct: 7005 PPYFVTELEP-LEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNV--- 7060
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L V+++D G+Y C +++IG SS RI+ PP
Sbjct: 7061 -ATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPP 7102
Score = 61.3 bits (142), Expect = 1e-08
Identities = 61/222 (27%), Positives = 86/222 (38%), Gaps = 18/222 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N SA L V P F K LE + +CK +P+ W
Sbjct: 8209 YTCYASNIAGKDSCSAHLGVQE-PPRFIKK-LEPSRIVKQDEFTRYECKIGGSPEIKVLW 8266
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I K F+ L + LS +D G YTC A N G+ S L V P
Sbjct: 8267 YKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
F +K P I + V L C P ++ KD +L K+ KI
Sbjct: 8327 IFRKK-PHPIETLKGADVHLECELQGTPPFHVSW--------YKDKRELRSGKKYKIMSE 8377
Query: 178 ---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I NV +D+G+Y+C + +G + + ++ PP
Sbjct: 8378 NFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP 8419
Score = 61.3 bits (142), Expect = 1e-08
Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 16/227 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N + ++ SSA+L + K P F ++ E + +C
Sbjct: 9054 YSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESAD--FECHVTGTQPIKV 9111
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV-- 114
+W KD+ I +GGK ++ + +L + ++ + D G YTC A N+ G D +L +
Sbjct: 9112 SWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 9171
Query: 115 -LRAPRFLEKLPPRI-TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
L P F ++L + + NS A PI W N + I+ +S+ +
Sbjct: 9172 RLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPI---TVAWYKNNIEIQPTSNCEIT-- 9226
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
K + L + ++D G Y C V + G + I+ P PP
Sbjct: 9227 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 9273
Score = 60.9 bits (141), Expect = 1e-08
Identities = 57/220 (25%), Positives = 88/220 (40%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVL--SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y + +N +S A LRVL ++ PSF K +++ G ++ ++CK + +
Sbjct: 6138 YTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKV--LGSSIHMECKVSGSLPISA 6195
Query: 60 TWKKDNIVIGAGGK-RFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I K R + + L + L +D YTC N G D G L V
Sbjct: 6196 QWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE 6255
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P FL K P R A +S V P W + + + ++ ++
Sbjct: 6256 PPSFLVK-PGRQQAIPDSTVEFKAILKGTPPFKIK--WFKDDVELVSGPKCFIG--LEGS 6310
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +Y+V S G Y C V + +G S L + PP
Sbjct: 6311 TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 6350
Score = 60.9 bits (141), Expect = 1e-08
Identities = 54/222 (24%), Positives = 87/222 (39%), Gaps = 13/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK-PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+A N + A SSA L + K P F L+ + + + G V +C+ + +
Sbjct: 8017 YSCKADNSVGAVASSAVLVIKERKLPPFFARKLK-DVHETLGFPVAFECRINGSEPLQVS 8075
Query: 61 WKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-- 115
W KD +++ F+ L I Q + G Y C A N GT S +LI+
Sbjct: 8076 WYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEH 8135
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P F + P + + C+ PI T W + I+ + + +
Sbjct: 8136 EVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT---WAKDNREIRPGGNYKMT--LV 8190
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ LT+ V D G Y C + G+ S L ++ PP
Sbjct: 8191 ENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPP 8232
Score = 60.5 bits (140), Expect = 2e-08
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N S L V PSF P + V K + P W
Sbjct: 6234 YTCKVSNVAGDDACSGILTVKE-PPSFLVKPGRQQAIPDS--TVEFKAILKGTPPFKIKW 6290
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD++ + +G K FI G+ L + + G YTC N G+D L+V P
Sbjct: 6291 FKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPP 6350
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
+F++KL + L C P + + N + L +SD Y + ID
Sbjct: 6351 KFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHEL---PASDKY--RMTFIDSV 6405
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + N+S D GD+ C ++ G S ++ ++ PP
Sbjct: 6406 AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 6444
Score = 60.5 bits (140), Expect = 2e-08
Identities = 104/421 (24%), Positives = 168/421 (39%), Gaps = 45/421 (10%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
PGPPG ++L RSS+++ W G ITGYM+ W +++ P ++
Sbjct: 22683 PGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTP--PAGLKA 22740
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
Y T+ T L Y+ RI A+N G G+P A P + D+ +
Sbjct: 22741 TSY------TI-TGLTENQEYKIRIYAMNSEGLGEP-ALVPGTPKAEDRMLPPEIELDAD 22792
Query: 335 GGKTGDLTITWT-PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISS 393
K + T L ++ P K W R+ E ++ + +V +
Sbjct: 22793 LRKVVTIRACCTLRLFVPIKGRPAPEVK--WARDHGE-SLDKASIESTSSYTLLIVGNVN 22849
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPID 453
+ Y + V+ G +S V + D P PQ + + T++ +TW+P
Sbjct: 22850 RFDSGKYILTVEN----SSGSKSAFVNV-RVLDTPG-PPQDLKVKEVTKTSVTLTWDP-- 22901
Query: 454 QSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTR----NWALIVGLQPDTYYYVKVMA 509
L G G ++K + E +E Y + T +W + LQ YY +V+A
Sbjct: 22902 ---PLLDG---GSKIKNYIVEKRESTRKAYSTVATNCHKTSWK-VDQLQEGCSYYFRVLA 22954
Query: 510 FNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYK 568
N G G +E E KA ++P + D T V + +P ++ +LGY
Sbjct: 22955 ENEYGIGLPAET-AESV--KASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYI 23011
Query: 569 VRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG--DGR-MSSPTI 625
V + D T+ EA I+ +I G+ Y+ RV A + G D R +S P I
Sbjct: 23012 VEMQTKGSDKWATCATV----KVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVI 23067
Query: 626 A 626
A
Sbjct: 23068 A 23068
Score = 60.1 bits (139), Expect = 3e-08
Identities = 55/219 (25%), Positives = 82/219 (37%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y E N++ +S VL + P F K PL G L CK +
Sbjct: 5014 YTFEISNEVGSSSCETTFTVLDRDIAPFFTK-PLR-NVDSVVNGTCRLDCKIAGSLPMRV 5071
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+W KD I A + F+ +L I ++ +D G +TC A N G+ +S G LIV
Sbjct: 5072 SWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE 5131
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P F+ K + ++V P+ W + Y+ K
Sbjct: 5132 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPL---TIRWFKGNKELVSGGSCYITKEAL-- 5186
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
L +Y V SD G Y C V + G + L ++ P
Sbjct: 5187 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEP 5225
Score = 60.1 bits (139), Expect = 3e-08
Identities = 73/335 (21%), Positives = 129/335 (38%), Gaps = 36/335 (10%)
Query: 24 LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITEN---G 80
+KP+F + +++ G ++ ++ PKPT TW KD + + + +T++
Sbjct: 24159 VKPAFSSYSVQV------GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 24212
Query: 81 NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHC 140
L I++ +DD G Y N G + ++ L P PP+ + + V
Sbjct: 24213 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD-----PPKGPVKFDDVSAESI 24267
Query: 141 NADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSA 200
+P L T N + K + V + T+ L +Y+ + A
Sbjct: 24268 TLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRI-FA 24326
Query: 201 IGRISSHVQLRIE--------GPPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYML 251
R L + PGPPG I + S+ ++W + N+ G P+ GY L
Sbjct: 24327 ENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHL 24386
Query: 252 TGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS 311
+ + W +++ I + + N L YEFR+ A NI+G G+ S
Sbjct: 24387 ERKERNSILWTKVNKTIIHDTQFKAQN----------LEEGIEYEFRVYAENIVGVGKAS 24436
Query: 312 APSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
S + P + P K ++T+ WT
Sbjct: 24437 KNSECYVAR--DPCDPPGTPEPIMVKRNEITLQWT 24469
Score = 60.1 bits (139), Expect = 3e-08
Identities = 121/532 (22%), Positives = 206/532 (38%), Gaps = 68/532 (12%)
Query: 4 CEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFTWK 62
CE +KA+ A +R LS+K S K + T +GG+V + E K TW
Sbjct: 28378 CETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWS 28437
Query: 63 KDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDE--SRGRLIV---LRA 117
AG I++ + + QL + AKN+ G + + G + V +
Sbjct: 28438 H------AG----ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIIT 28487
Query: 118 PRF-LEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNK-RIK 174
P L +P ++T ++ V L P + W +GL +K+S + +K K
Sbjct: 28488 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKP--KPSISWLKDGLPLKESEFVRFSKTENK 28545
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG-PPGGVQILGIQRSSVT 233
I L+I N G Y ++ +A+ RI+ + + GPP P G ++ I+ SV
Sbjct: 28546 IT---LSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVI 28602
Query: 234 LEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVST-TLLP 291
L W ++ G IT Y + R + W ++ ++ R T L+
Sbjct: 28603 LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV------------ARTTFKVPNLVK 28650
Query: 292 WAIYEFRIQAINILGPGQPSAPS-----PQFSTSGDKPYEAPANVSGGGGKTGDLTITW- 345
A Y+FR++A N G QP S QF G NV+ G +++TW
Sbjct: 28651 DAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDG-----MSLTWD 28705
Query: 346 TPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQ 405
P+ G H + ++ + + +Q + I + Y +V
Sbjct: 28706 APVYDGGSEVTGFHVE---KKERNSILWQKV---NTSPISGREYRATGLVEGLDYQFRVY 28759
Query: 406 AFNDIG---PGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGK 462
A N G P S+ S D P + R + + WNP R+ K
Sbjct: 28760 AENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRE----TITLKWNP--PLRDG-GSK 28812
Query: 463 LIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAG 514
++G+ ++ K++ E + + + GL P Y +++A N+ G
Sbjct: 28813 IVGYSIE--KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVG 28862
Score = 59.7 bits (138), Expect = 3e-08
Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 15/196 (7%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
W+ +G +K +SD K I L + +D G Y +++ +G ++ + +++
Sbjct: 15347 WHKDGKEVK-ASDRLTMKNDHISA-HLEVPKSVRADAGIYTITLENKLGSATASINVKVI 15404
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
G PGP ++ I +SS L W G PI Y+L R T+ IP VM
Sbjct: 15405 GLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY------IP-VM 15457
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQ-PSAPSPQFSTSGDKPYEAPANV 331
+ K + L+P Y FR++A+N +G G+ +P + +P + P +V
Sbjct: 15458 SGE----NKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 15513
Query: 332 SGGGGKTGDLTITWTP 347
+TITW P
Sbjct: 15514 EVHNPTAEAMTITWKP 15529
Score = 59.7 bits (138), Expect = 3e-08
Identities = 77/319 (24%), Positives = 123/319 (38%), Gaps = 32/319 (10%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE---NGNLIIRQLSRDDEGVYTC 97
E N LK + P P+ +WKK + + + N LI+ + D G YT
Sbjct: 20923 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20982
Query: 98 VAKNQYGTDESRGRLIVLRAPRFLEKLPPR---ITAQVNSVVFLHCNAD-----VDPILD 149
KN GT E + V+ P + P + +TA+ ++ + D + IL+
Sbjct: 20983 TLKNVAGTKEGTISIKVVGKPG-IPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILE 21041
Query: 150 TAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSD-VGDYECVVKSAIGRISSHV 208
N+ + + + ++ G + VS + G E + I ++ H
Sbjct: 21042 KRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPI--VARH- 21098
Query: 209 QLRIEGPPGPPGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P PP I+ ++ SV+L WTD + G PITGY L + + W
Sbjct: 21099 PFDVPDAPPPPN---IVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLW------ 21149
Query: 268 IPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEA 327
++ R R T L YEFR+ AIN+ G G+PS PS P +
Sbjct: 21150 ----KRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVAL--DPIDP 21203
Query: 328 PANVSGGGGKTGDLTITWT 346
P +T+ WT
Sbjct: 21204 PGKPEVINITRNSVTLIWT 21222
Score = 59.3 bits (137), Expect = 4e-08
Identities = 50/219 (22%), Positives = 82/219 (37%), Gaps = 12/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + S L V P F + P + + V LK T W
Sbjct: 5672 YTCSATNKAGHNQCSGHLTVKE-PPYFVEKPQSQDV--NPNTRVQLKALVGGTAPMTIKW 5728
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQL---SRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KDN + +G R + ++ +L D G Y C N GT S+ L V P
Sbjct: 5729 FKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 5788
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
+F++K P + + C P + ++ + N + + IDG
Sbjct: 5789 QFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-----IDGL 5843
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + + G Y C ++ G S ++L+++ PP
Sbjct: 5844 ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 5882
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/256 (24%), Positives = 99/256 (38%), Gaps = 26/256 (10%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW-TD 238
LT+ N + +D G Y V++ G S +++ PGPPG + + R S TL W
Sbjct: 29340 LTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAP 29399
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
G I Y++ R +W VISE ++ + N L Y FR
Sbjct: 29400 LLDGGARIHHYVVEKREASRRSWQVISEKC--TRQIFKVN---------DLAEGVPYYFR 29448
Query: 299 IQAINILGPGQP-SAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPG 357
+ A+N G G+P P P +T P P + + W L G
Sbjct: 29449 VSAVNEYGVGEPYEMPEPIVATEQPAP---PRRLDVVDTSKSSAVLAW--LKPDHDGGSR 29503
Query: 358 I-HYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPES 416
I Y + R+ GS+ ++ G+ + T Y+ +V+A ND G
Sbjct: 29504 ITGYLLEMRQKGSDFWVEA------GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPR 29557
Query: 417 EVVTIYSAEDMPQVAP 432
E + ++ PQ+ P
Sbjct: 29558 EAFSSVIIKE-PQIEP 29572
Score = 58.8 bits (136), Expect = 6e-08
Identities = 103/417 (24%), Positives = 166/417 (39%), Gaps = 47/417 (11%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PPG +++ I R+SVTL WT+ G +TGY++ R + +W M+
Sbjct: 21200 PIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSW----------MK 21249
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDK-PYEAPANVS 332
+ N + A T L+ YEFRI+A N G SAPS T K YEAP V
Sbjct: 21250 ANHVNVPECAFTVTDLVEGGKYEFRIRAKNT--AGAISAPSESTETIICKDEYEAPTIVL 21307
Query: 333 GGGGKTGDLTI----TWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV 388
K G LTI T S+ P K W + G ++ S + + + +
Sbjct: 21308 DPTIKDG-LTIKAGDTIVLNAISILGKP--LPKSSWSKAGKDIR-PSDITQITSTPTSSM 21363
Query: 389 VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
+ I + + A N G E VT+ D+P P V + ++ +T
Sbjct: 21364 LTIKYATRKDAGEYTITATNPFGTKVEHVKVTVL---DVPG-PPGPVEISNVSAEKATLT 21419
Query: 449 WN-PIDQSRERLRGKLIGHR---LKYWKQENKE-EECIYYLSRTTRNWALIVGLQPDTYY 503
W P++ ++ ++ R W +++ + C + ++ LI G + Y
Sbjct: 21420 WTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK------LIQGNE----Y 21469
Query: 504 YVKVMAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-E 561
+V A N G+G P ++ R P PP V T V W+ +P ++
Sbjct: 21470 IFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK--RPVDDGG 21527
Query: 562 EPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ GY V E + + P+ L ++ + G +Y RV A + G G
Sbjct: 21528 SEITGYHVERRE-KKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENRAGIG 21582
Score = 58.0 bits (134), Expect = 1e-07
Identities = 52/218 (23%), Positives = 88/218 (40%), Gaps = 11/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + SA L V PSF + P ++ G NVT + P + +W
Sbjct: 8679 YTCIATNMAGSDECSAPLTVRE-PPSFVQKPDPMDVL--TGTNVTFTSIVKGTPPFSVSW 8735
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDD---EGVYTCVAKNQYGTDESRGRLIVLRAP 118
K + + G + ++ ++ +L D G YTC+ N+ G L +
Sbjct: 8736 FKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA 8795
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+F+++L + ++ PI T W NG+ + S + K
Sbjct: 8796 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVT---WKKNGINVTPSQRCNITTTEK--SA 8850
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I + ++ D G Y C +++A G+ S Q+ I PP
Sbjct: 8851 ILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPP 8888
Score = 57.6 bits (133), Expect = 1e-07
Identities = 58/221 (26%), Positives = 84/221 (38%), Gaps = 14/221 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ KN A L VL +K P ++ + G TL+C P+ + W
Sbjct: 8490 YTCQIKNDAGMQECFATLSVLEPATIVEK-PESIKV--TTGDTCTLECTVAGTPELSTKW 8546
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA- 117
KD + + K F + L I ++ D GVY+ +N G D L V
Sbjct: 8547 FKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRT 8606
Query: 118 --PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F KL +SVV + C P + + W H G I SS +
Sbjct: 8607 VPPSFTRKLKETNGLSGSSVV-MECKVYGSPPISVS--WFHEGNEI--SSGRKYQTTLTD 8661
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ LT+ + SD GDY C+ + G L + PP
Sbjct: 8662 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPP 8702
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/322 (22%), Positives = 131/322 (40%), Gaps = 34/322 (10%)
Query: 38 YGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE----NGNLIIRQLSRDDEG 93
Y G N+ + P P T +D + + A RF TE N + +++ D G
Sbjct: 27414 YVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKAT-MRFNTEITAENLTINLKESVTADAG 27472
Query: 94 VYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPIL--DTA 151
Y A N GT ++ ++VL P PP ++ + +P +
Sbjct: 27473 RYEITAANSSGTTKAFINIVVLDRPG-----PPTGPVVISDITEESVTLKWEPPKYDGGS 27527
Query: 152 YLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQ-- 209
+ N+ L+ + S+ ++ + + + ++ + + ++ G IS H+
Sbjct: 27528 QVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFG-ISDHIDSA 27586
Query: 210 -LRIEGP---PGPPGGVQILGIQRSSVTLEWTDSNSNG-RPITGYMLTGRTHWNSTWYVI 264
+ ++ P PGPP + + R S+T+ W + SNG + GY L + + W
Sbjct: 27587 CVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKA 27646
Query: 265 SENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS-PQFSTSGDK 323
++ V R K T+S L IYEFR+ A N G G+PS PS P + +
Sbjct: 27647 NKL------VIRTTHFKVTTISAGL----IYEFRVYAENAAGVGKPSHPSEPVLAIDACE 27696
Query: 324 PYEAPANVSGGGGKTGDLTITW 345
P P NV ++++W
Sbjct: 27697 P---PRNVRITDISKNSVSLSW 27715
Score = 57.2 bits (132), Expect = 2e-07
Identities = 86/382 (22%), Positives = 146/382 (38%), Gaps = 38/382 (9%)
Query: 167 LYVNKRIKIDGG-----ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
L + +R+ ID +L + + D G Y V++ G + + + PGPP
Sbjct: 15675 LPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPIN 15734
Query: 222 VQILGIQRSSVTLEWTDS-NSNGRPITGYMLT--GRTHWNSTWYVISENIPNVMEVDRYN 278
I+++SV +W + G I Y L +T +S W V++ + + +Y+
Sbjct: 15735 FVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHC----KYS 15790
Query: 279 GRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKT 338
T L+ Y FR++A N GPG P P + P +AP +
Sbjct: 15791 -------VTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS 15843
Query: 339 GDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
+ + W NG I +W EV + ++
Sbjct: 15844 NSMLVKWN---EPKDNGSPI--LGYWLEK-REVNSTHWSRVNKSLLNALKANVDGLLEGL 15897
Query: 399 PYDVKVQAFNDIGPG---PESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQS 455
Y +V A N GPG P S+ T + P P + +ST + + W P
Sbjct: 15898 TYVFRVCAENAAGPGKFSPPSDPKTAHDPISPP--GPPIPRVTDTSSTTIELEWEP---P 15952
Query: 456 RERLRGKLIGHRL-KYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAG 514
G+++G+ + K N+ C + + R + + ++ Y ++V A N+AG
Sbjct: 15953 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK-VRQYT-VKEIREGADYKLRVSAVNAAG 16010
Query: 515 EGPESERYLERTFRKAPQKPPA 536
EGP E + PQ+PPA
Sbjct: 16011 EGPPGE--TQPVTVAEPQEPPA 16030
Score = 57.2 bits (132), Expect = 2e-07
Identities = 101/469 (21%), Positives = 173/469 (36%), Gaps = 48/469 (10%)
Query: 84 IRQLSRDDEGVYTCVAKNQYGT----DESRGRLIV---LRAPRFLEKLPPRITAQVNSVV 136
+ +L+ D + A+N + ES G +IV + PR + + R V +
Sbjct: 26673 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 26732
Query: 137 FLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL-TIYNVSLSDVGDYEC 195
L NAD+ W +G+ I++ + + I D L T+ + D G Y
Sbjct: 26733 VLKINADIAGRPLPVISWAKDGIEIEERARTEI---ISTDNHTLLTVKDCIRRDTGQYVL 26789
Query: 196 VVKSAIGRISSHVQLRIEGPPGPPGG-VQILGIQRSSVTLEW-TDSNSNGRPITGYMLTG 253
+K+ G S V ++ PGPP G ++I G+ +L W G I Y++
Sbjct: 26790 TLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEK 26849
Query: 254 RTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAP 313
R + W + + + + T LL Y FR+ +N G G+P
Sbjct: 26850 RETSHLAWTICEGEL-----------QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLES 26898
Query: 314 SPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEF 373
+ P ++ +T+ W+ P S G I I RR E
Sbjct: 26899 VAIKALDPFTVPSPPTSLEITSVTKESMTLCWS-RPES-DGGSEISGYIIERR-----EK 26951
Query: 374 QSLLLKKYGNIGTYVVHISSTYFY--TPYDVKVQAFNDIGPGPESEVVTIYSAED----- 426
SL + Y + + ST Y+ +V A N G SE + AED
Sbjct: 26952 NSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP 27011
Query: 427 MPQVAPQLVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLS 485
P P++V + T + + W P+ + G+ ++Y K ++ + +
Sbjct: 27012 SPPSKPKIVDS---GKTTITIAWVKPLFDG----GAPITGYTVEYKKSDDTDWKTSIQSL 27064
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKP 534
R T I GL Y +V + N G S+ + ++ ++P
Sbjct: 27065 RGTE--YTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEP 27111
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/224 (24%), Positives = 86/224 (38%), Gaps = 17/224 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C+A+N + + S R+ L PSF + ++E + G VTL C+ +
Sbjct: 7076 YTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ--TVGLPVTLTCRLNGSAPIQV 7133
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W +D +++ F+ L I Q G Y+C A N GT S RL R
Sbjct: 7134 CWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARL-TAR 7192
Query: 117 APR---FLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
P+ F + P I C+ P+ T W+ + I+ + +
Sbjct: 7193 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRIT---WSKDNKEIRPGGNYTIT-- 7247
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ L I V D G Y C + +G+ QL ++ PP
Sbjct: 7248 CVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPP 7291
Score = 56.4 bits (130), Expect = 3e-07
Identities = 50/218 (22%), Positives = 84/218 (38%), Gaps = 10/218 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ N SA L V +P+ LE +G L CK P TW
Sbjct: 5203 YTCKVSNVAGGVECSANLFVK--EPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITW 5260
Query: 62 KKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
++ I K F+ L + + +D G Y C A+N+ G+D +IV +P
Sbjct: 5261 FANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 5320
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F ++ P + V+ L A P + + ++ LR ++ +
Sbjct: 5321 YFTKEFKPIEVLKEYDVMLLAEVAGTPP-FEITWFKDNTILRSGRKYKTFIQDHLV---- 5375
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +D G+Y+C V + +G ++ + PP
Sbjct: 5376 SLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 5413
Score = 55.6 bits (128), Expect = 5e-07
Identities = 70/295 (23%), Positives = 115/295 (38%), Gaps = 24/295 (8%)
Query: 83 IIRQLSRDDEGVYTCVAKNQYGTDESR-GRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
++R L+ +E + +A N G R R ++++ L +L R Q + N
Sbjct: 21950 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDN 22009
Query: 142 ADVD-PILDT---AYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV 197
V+ P+L W +K + VN L I SD G Y
Sbjct: 22010 IKVEIPVLGRPKPTVTWKKGDQILKQTQR--VNFETTATSTILNINECVRSDSGPYPLTA 22067
Query: 198 KSAIGRISSHVQLRIEGPPGPP-GGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRT 255
++ +G + + +++ PGPP G ++ + VT W N G PI+ Y++ R
Sbjct: 22068 RNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQ 22127
Query: 256 HWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSP 315
++TW ++ + +AT TT L Y+FR++A N G G P S
Sbjct: 22128 TDSTTWVELATTV--------IRTTYKATRLTTGLE---YQFRVKAQNRYGVG-PGITSA 22175
Query: 316 QFSTSGDKPYEAPANVSGGGGKTGD-LTITWTPLPTSLQNGPGIHYKIFWR-RNG 368
+ P T D +TI+W P S P + Y + + RNG
Sbjct: 22176 CIVANYPFKVPGPPGTPQVTAVTKDSMTISWHE-PLSDGGSPILGYHVERKERNG 22229
Score = 55.2 bits (127), Expect = 7e-07
Identities = 63/249 (25%), Positives = 99/249 (39%), Gaps = 22/249 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y C+A+N + +S L V K PSF + +++ + G V C + +
Sbjct: 8958 YICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQE--TVGLPVVFDCAISGSEPISV 9015
Query: 60 TWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL- 115
+W KD + F+ L I + R G Y+C A N G+ S RLI+
Sbjct: 9016 SWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTE 9075
Query: 116 -RAPRFLE-KLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
+ P F + +L P + A V C+ PI W + I+ ++
Sbjct: 9076 GKNPPFFDIRLAP-VDAVVGESADFECHVTGTQPI---KVSWAKDSREIRSGGKYQIS-- 9129
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSV 232
+ LT+ V D G Y C + +G+ S QL I+ PP +R S
Sbjct: 9130 YLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFT-----KRLSE 9184
Query: 233 TLEWTDSNS 241
T+E T+ NS
Sbjct: 9185 TVEETEGNS 9193
Score = 55.2 bits (127), Expect = 7e-07
Identities = 61/221 (27%), Positives = 94/221 (42%), Gaps = 21/221 (9%)
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
GPP P + + +S+ ++W + NG PI GY L R ++ W +++++ N +
Sbjct: 15828 GPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNAL- 15886
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
+A V LL Y FR+ A N GPG+ S PS T+ D P P
Sbjct: 15887 --------KANVD-GLLEGLTYVFRVCAENAAGPGKFSPPSDP-KTAHD-PISPPGPPIP 15935
Query: 334 GGGKTGDLTI--TWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHI 391
T TI W P P G + Y + + G+ E+ S +K + Y V
Sbjct: 15936 RVTDTSSTTIELEWEP-PAFNGGGEIVGYFVDKQLVGTN-EW-SRCTEKMIKVRQYTV-- 15990
Query: 392 SSTYFYTPYDVKVQAFNDIGPGP--ESEVVTIYSAEDMPQV 430
Y ++V A N G GP E++ VT+ ++ P V
Sbjct: 15991 KEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAV 16031
Score = 54.8 bits (126), Expect = 9e-07
Identities = 54/220 (24%), Positives = 89/220 (40%), Gaps = 12/220 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS--LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y E KN + S + + V + PSF + ++ G +V L+C+ + +
Sbjct: 7641 LYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAI--LGASVVLECRVSGSAPIS 7698
Query: 59 FTWKKDN--IVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W +D IV G + +EN L + L D G+YTCVA N G+DE L V
Sbjct: 7699 VGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 7758
Query: 116 RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P F E+ P + + P + L +S ++ + +
Sbjct: 7759 EPPSF-EQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVT- 7816
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
EL ++ V + GDY C+V + G S L ++ P
Sbjct: 7817 ---ELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP 7853
Score = 54.8 bits (126), Expect = 9e-07
Identities = 93/442 (21%), Positives = 159/442 (35%), Gaps = 38/442 (8%)
Query: 83 IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLH 139
+I L++ +E ++ VA N+ G + R + + A + + P + V L
Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLK 24175
Query: 140 CNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
+ W +GL +K ++ + V +D L+I D G Y V +
Sbjct: 24176 IEVPISGRPKPTITWTKDGLPLKQTTRINVTD--SLDLTTLSIKETHKDDGGQYGITVAN 24233
Query: 200 AIGRISSHVQL-RIEGPPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHW 257
+G+ ++ +++ ++ P P G V+ + S+TL W + G IT Y++ R
Sbjct: 24234 VVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTT 24293
Query: 258 NSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI-YEFRIQAINILGPGQPSAPSPQ 316
+ W V+S + R T+ T L Y+FRI A N G P
Sbjct: 24294 TTVWDVVSATV------------ARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 24341
Query: 317 FSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSL 376
+ K P + I W P + P I Y + E S+
Sbjct: 24342 VAQYPYKEPGPPGTPFATAISKDSMVIQWHE-PVNNGGSPVIGYHL------ERKERNSI 24394
Query: 377 LLKKYGNIGTYVVHISSTYFY--TPYDVKVQAFNDIGPGPESEVVTIYSAEDM--PQVAP 432
L K + + Y+ +V A N +G G S+ Y A D P P
Sbjct: 24395 LWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTP 24454
Query: 433 QLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWA 492
+ + + N L T P+ + G ++ R + K +
Sbjct: 24455 EPIMVKR-NEITLQWT-KPVYDGGSMITGYIVEKRDLPDGRWMKAS-----FTNVIETQF 24507
Query: 493 LIVGLQPDTYYYVKVMAFNSAG 514
+ GL D Y +V+A N+AG
Sbjct: 24508 TVSGLTEDQRYEFRVIAKNAAG 24529
Score = 54.8 bits (126), Expect = 9e-07
Identities = 96/407 (23%), Positives = 153/407 (37%), Gaps = 36/407 (8%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITEN---GNLIIRQLSRDDEGVYTCV 98
G L+ P PT W + + I + I LI++ R D G Y
Sbjct: 24567 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 24626
Query: 99 AKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPIL-DTAYLWNHN 157
A N G+ + VL P PP QV V C+ P L D +H
Sbjct: 24627 ASNVAGSKSFPVNVKVLDRPG-----PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHY 24681
Query: 158 GLRIKDSSDL---YVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
+ +++S L V + + ++T V V K +G + ++
Sbjct: 24682 VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741
Query: 215 P---PGPPGGVQILGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIPN 270
P PGPP +++ I + S+T+ W +S+ G I GY++ R W I N
Sbjct: 24742 PFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRW--IKCNKRR 24799
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYE--AP 328
+ ++ R R T L YEFR+ A N G G+PS P+ + + D ++ P
Sbjct: 24800 ITDL-----RLRV---TGLTEDHEYEFRVSAENAAGVGEPS-PATVYYKACDPVFKPGPP 24850
Query: 329 ANVSGGGGKTGDLTITW-TPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTY 387
N +T+ W P+ G I + E E+Q ++ +
Sbjct: 24851 TNAHIVDTTKNSITLAWGKPI---YDGGSEILGYVVEICKADEEEWQ--IVTPQTGLRVT 24905
Query: 388 VVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQL 434
IS + Y ++V A N +G G + V ED + AP+L
Sbjct: 24906 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLE-APEL 24951
Score = 54.4 bits (125), Expect = 1e-06
Identities = 86/373 (23%), Positives = 143/373 (38%), Gaps = 48/373 (12%)
Query: 162 KDSSDLYVNKR--IKIDGGELTIYNVSL--SDVGDYECVVKSAIGRISSHVQLRIEGPPG 217
KD +D+ + R IK L + + SD G Y VV+++ G Q+ + PG
Sbjct: 17781 KDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG 17840
Query: 218 PP-GGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVD 275
PP G V + + + + W + G IT Y++ + W M V
Sbjct: 17841 PPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVW----------MPVT 17890
Query: 276 RYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGG 335
+ + VS LL Y FRI A N+ G P + + +AP
Sbjct: 17891 SASAKTTCKVS-KLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17949
Query: 336 GKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTY 395
+TW G I I +E + + K++ + +H T
Sbjct: 17950 VTKDSALVTWN---KPHDGGKPITNYI--------LEKRETMSKRWARVTKDPIH-PYTK 17997
Query: 396 FYTP-------YDVKVQAFNDIG---PGPESEVVTIYS--AEDMPQVAPQLVSARSFNST 443
F P Y+ +V A N+IG P P S+ V A+ P V P+ +
Sbjct: 17998 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDT---TCN 18054
Query: 444 ALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL-IVGLQPDTY 502
++++TW P R K++G+ ++Y K ++E + + + GL+
Sbjct: 18055 SVDLTWQP---PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQT 18111
Query: 503 YYVKVMAFNSAGE 515
Y +V+A N+AGE
Sbjct: 18112 YKFRVLAVNAAGE 18124
Score = 54.4 bits (125), Expect = 1e-06
Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 14/167 (8%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW-TD 238
LTI N + +D G Y +++ + S + +++ PGPP + + + + S L W
Sbjct: 27169 LTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 27228
Query: 239 SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFR 298
N G P+ Y + R W ++ N + + T L AIY FR
Sbjct: 27229 ENDGGAPVKNYHIEKREASKKAWVSVTNNC-----------NRLSYKVTNLQEGAIYYFR 27277
Query: 299 IQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITW 345
+ N G G P A + + +KP P + +++TW
Sbjct: 27278 VSGENEFGVGIP-AETKEGVKITEKP-SPPEKLGVTSISKDSVSLTW 27322
Score = 54.0 bits (124), Expect = 2e-06
Identities = 63/248 (25%), Positives = 96/248 (38%), Gaps = 16/248 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N++ + S ++ P F K + T G V L+ E + W
Sbjct: 7455 YHCKATNEVGSDTCSCSVKFKE-PPRFVKKLSDTSTL--IGDAVELRAIVEGFQPISVVW 7511
Query: 62 KKDN--IVIGAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
KD ++ + R FI L + + G Y C KN G E L VL
Sbjct: 7512 LKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEP 7571
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
R +EK P +T + L C P L W +G + S ++ K+
Sbjct: 7572 ARIIEK-PEPMTVTTGNPFALECVVTGTPELSAK--WFKDGRELSADSKHHITFINKV-- 7626
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL----GIQRSSVT 233
L I +SD G Y VK+++G+ + V + + PP ++ L I +SV
Sbjct: 7627 ASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAILGASVV 7686
Query: 234 LEWTDSNS 241
LE S S
Sbjct: 7687 LECRVSGS 7694
Score = 53.6 bits (123), Expect = 2e-06
Identities = 82/404 (20%), Positives = 151/404 (37%), Gaps = 32/404 (7%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
W +R+K++ + + D LT+ + D G Y +++ G + V + +
Sbjct: 29608 WKLEEMRLKETDRVSITTTK--DRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVI 29665
Query: 214 GPPGP-PGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
G PGP G +++ + S L W + + G IT Y++ R + W +++ ++
Sbjct: 29666 GRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV--- 29722
Query: 272 MEVDRYNGRKRATVSTT-LLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
KR + T L + Y FR+ + N G +P +P + P AP
Sbjct: 29723 ---------KRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTR 29773
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
++I W +G G +W + E ++L K + +
Sbjct: 29774 PEVYHVSANAMSIRW---EEPYHDG-GSKIIGYW---VEKKERNTILWVKENKVPCLECN 29826
Query: 391 ISSTYFY--TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVT 448
T Y + A N G SE A++ P AP + +++
Sbjct: 29827 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQN-PVDAPGRPEVTDVTRSTVSLI 29885
Query: 449 WN-PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
W+ P ++ G +I + + + +C Y + + N+ + L Y +V
Sbjct: 29886 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTI--VSDNFFTVTALSEGDTYEFRV 29943
Query: 508 MAFNSAGE-GPESERYLERTFRKAPQKPPASVNVWAH-DPTTLR 549
+A N+AG SE T R P A ++ H D T+R
Sbjct: 29944 LAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR 29987
Score = 53.2 bits (122), Expect = 3e-06
Identities = 55/207 (26%), Positives = 83/207 (40%), Gaps = 11/207 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C N++ A +L P+F K +L G G VTL+ + + TW
Sbjct: 4828 YECVVANEVGKCGCMAT-HLLKEPPTFVKKVDDLIALG--GQTVTLQAAVRGSEPISVTW 4884
Query: 62 KKDNIVIGAGGK-RFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
K VI GK + NG LII + G YTC+A+N+ G+ S G LIV
Sbjct: 4885 MKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPA 4944
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +E+ I L P L W +G + S ++ K +
Sbjct: 4945 KIIER-AELIQVTAGDPATLEYTVAGTPELKPK--WYKDGRPLVASKKYRIS--FKNNVA 4999
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRIS 205
+L Y+ L D G Y + + +G S
Sbjct: 5000 QLKFYSAELHDSGQYTFEISNEVGSSS 5026
Score = 53.2 bits (122), Expect = 3e-06
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 15/191 (7%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG-PPGGVQILGIQRSSVTLEWT- 237
L +Y+ SD G Y +K+ G + +++ G PG P G ++ + ++TL+W
Sbjct: 20967 LIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAP 21026
Query: 238 DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
+ G IT Y+L R N+ W + + +K T L Y F
Sbjct: 21027 PKDDGGSEITNYILEKRDSVNNKWVTCASAV-----------QKTTFRVTRLHEGMEYTF 21075
Query: 298 RIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT-PLPTSLQNGP 356
R+ A N G G+ P + +AP + + +++TWT P T
Sbjct: 21076 RVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPIT 21135
Query: 357 GIHYKIFWRRN 367
G H + F RN
Sbjct: 21136 GYHLE-FKERN 21145
Score = 53.2 bits (122), Expect = 3e-06
Identities = 103/420 (24%), Positives = 148/420 (35%), Gaps = 36/420 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PPG L I R +VTL+W + G IT Y++ R N W + N N++E
Sbjct: 22283 PIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRW--LKANFSNILE 22340
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGP-GQPSAPSPQFSTSGDKPYEAPANVS 332
TVS L A YEFR+ A N G PS PS + D EAP
Sbjct: 22341 -------NEFTVS-GLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDD--VEAPKIKV 22390
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS 392
K + + W ++G E+E + L K + T +V+
Sbjct: 22391 DVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKD 22450
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTW-NP 451
S T D PG ++ + D P ++ S ++W P
Sbjct: 22451 S----TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPP 22506
Query: 452 IDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFN 511
+D G I H + K+E S + L Y +VMA N
Sbjct: 22507 LDDG-----GAKIDHYI-VQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVN 22560
Query: 512 SAGEGP--ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKV 569
G G ESE L P PP + V ++ V W + E ++ Y V
Sbjct: 22561 KYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSE-IINYIV 22618
Query: 570 -RLWELDQDMSTAN-DTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIAF 627
R + Q N T+ + +K +S + G Y R++A N SPT F
Sbjct: 22619 ERRDKAGQRWIKCNKKTLTDLRYK----VSGLTEGHEYEFRIMA-ENAAGISAPSPTSPF 22673
Score = 52.8 bits (121), Expect = 4e-06
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 15/172 (8%)
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
EL I SD G Y +++ + IS + + + P P ++ I + SV L W
Sbjct: 14378 ELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEP 14437
Query: 239 SNSNG-RPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
+ +G P+TGY++ R TW + + + ++ TV L+ Y F
Sbjct: 14438 PDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDL----------EFTV-PDLVQGKEYLF 14486
Query: 298 RIQAINILGPGQPS-APSP-QFSTSGDKPYEAPANVSGGGGKTGDLTITWTP 347
++ A N GPG+P+ P ST P + P NV + +TW P
Sbjct: 14487 KVCARNKCGPGEPAYVDEPVNMSTPATVP-DPPENVKWRDRTANSIFLTWDP 14537
Score = 52.8 bits (121), Expect = 4e-06
Identities = 97/426 (22%), Positives = 171/426 (40%), Gaps = 38/426 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PPG + + I R++VTL+W + G ITGY++ + + W + + NV+E
Sbjct: 25529 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW--MKASFTNVLE 25586
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
+ TVS L+ YEFR+ A N G + S T+ D+ +AP N S
Sbjct: 25587 TE-------FTVSG-LVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDE-IDAP-NASL 25636
Query: 334 GGGKTGDLTITWTPLPTSLQ---NGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
K D+ + L+ G I + W ++G E+E + ++ I +
Sbjct: 25637 DP-KYKDVIVVHAGETFVLEADIRGKPIP-DVVWSKDGKELEETAARMEIKSTIQKTTLV 25694
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ T + +++G G +S +T+ D P + + + WN
Sbjct: 25695 VKDC-IRTDGGQYILKLSNVG-GTKSIPITV-KVLDRPGPPEGPLKVTGVTAEKCYLAWN 25751
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL---IVGLQPDTYYYVKV 507
P Q G + ++ E +E + + +T AL + L P Y +V
Sbjct: 25752 PPLQDG--------GANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRV 25803
Query: 508 MAFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE-EPLL 565
MA N G G P + P PP++ V A ++ V W +P ++ +
Sbjct: 25804 MAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTW--ARPVDDGGTEIE 25861
Query: 566 GYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTI 625
GY + + + T + + +L ++ + G SY RV A + G G S P++
Sbjct: 25862 GYILEKRDKEGVRWTKCNKKTLTDLRLR--VTGLTEGHSYEFRVAAENAAGVGEPSEPSV 25919
Query: 626 AFQIGD 631
++ D
Sbjct: 25920 FYRACD 25925
Score = 52.8 bits (121), Expect = 4e-06
Identities = 99/422 (23%), Positives = 165/422 (39%), Gaps = 39/422 (9%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
PPGPP ++ RSSV+L W+ G P+ GY++ + W + P ++
Sbjct: 25929 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTP--PTGLQ 25986
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
K+ TV T L Y FRI AIN G G+P A P + ++ +
Sbjct: 25987 ------GKQFTV-TKLKENTEYNFRICAINSEGVGEP-ATLPGSVVAQERIEPPEIELDA 26038
Query: 334 GGGKTGDLTITWT-PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHIS 392
K L + T L +++ P K W + + ++ + V+
Sbjct: 26039 DLRKVVVLRASATLRLFVTIKGRPEPEVK--WEK-AEGILTDRAQIEVTSSFTMLVIDNV 26095
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNP- 451
+ + Y++ ++ G ++ V + D P AP ++ R ++ ++W P
Sbjct: 26096 TRFDSGRYNLTLEN----NSGSKTAFVNV-RVLDSPS-APVNLTIREVKKDSVTLSWEPP 26149
Query: 452 -IDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
ID K+ + ++ K+E + + T+ I LQ YY +V+A
Sbjct: 26150 LIDGG-----AKITNYIVE--KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLAS 26202
Query: 511 NSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVR 570
N G G +E E P PP V + T + W + ++ + GY V
Sbjct: 26203 NEYGIGLPAET-TEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPE-SDGGSKITGYVV- 26259
Query: 571 LWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG--DGR-MSSPTIAF 627
E+ S T ++ LEA IS + G+ Y RV A + G D R + P IA
Sbjct: 26260 --EMQTKGSEKWSTCTQVK-TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIAR 26316
Query: 628 QI 629
I
Sbjct: 26317 DI 26318
Score = 52.8 bits (121), Expect = 4e-06
Identities = 56/226 (24%), Positives = 96/226 (42%), Gaps = 17/226 (7%)
Query: 400 YDVKVQAFNDIGPGP--ESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN-PIDQSR 456
Y +V+A N G G ES+ V +A P P + ++ V W+ PI
Sbjct: 27963 YIFRVRAVNKYGIGEPLESDSVVAKNAFVTPG-PPGIPEVTKITKNSMTVVWSRPIADGG 28021
Query: 457 ERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL-IVGLQPDTYYYVKVMAFNSAGE 515
+ G + K++ K L T R+ + GL ++ Y +V A N+AG+
Sbjct: 28022 SDISGYFLE------KRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQ 28075
Query: 516 GPESE--RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE-EPLLGYKVRLW 572
GP SE + + P PPA + + +++ + W +P + + GY V +
Sbjct: 28076 GPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWS--KPVYDGGSAVTGYVVEIR 28133
Query: 573 ELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
+ +++ T T + E +SN+ PG +Y RV A + G G
Sbjct: 28134 QGEEEEWTTVSTKGEVR-TTEYVVSNLKPGVNYYFRVSAVNCAGQG 28178
Score = 52.4 bits (120), Expect = 5e-06
Identities = 56/221 (25%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N+ S S + L PSF K +E T + + T + +P + TW
Sbjct: 5952 YQCIVSNE-GGSCSCSTRVALKEPPSFIKK-IENTTTVLKS-SATFQSTVAGSPPISITW 6008
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD+ ++ F+ L IR + G YTC AKN+ G + L+V
Sbjct: 6009 LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPA 6068
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +EK + + L C P L W +G +I S Y + + +
Sbjct: 6069 QIVEK-AKSVDVTEKDPMTLECVVAGTPELKVK--WLKDGKQIVPSR--YFSMSFENNVA 6123
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
I +V D G Y V++ G S LR+ PP
Sbjct: 6124 SFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPP 6164
Score = 52.4 bits (120), Expect = 5e-06
Identities = 58/207 (28%), Positives = 87/207 (42%), Gaps = 16/207 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + S L V + P F + P + +G +V L+C+ P W
Sbjct: 7362 YICEAHNGVGDASCSTALTVKA-PPVFTQKPSPVGAL--KGSDVILQCEISGTPPFEVVW 7418
Query: 62 KKDNIVIGAGGKRFITE---NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD + K IT + +L I L D G Y C A N+ G+D + P
Sbjct: 7419 VKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 7478
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW-NHNGLRIKDSSDLYVNKRIK-ID 176
RF++KL T ++V A V+ + +W G I++S N RI ID
Sbjct: 7479 RFVKKLSDTSTLIGDAV---ELRAIVEGFQPISVVWLKDRGEVIRESE----NTRISFID 7531
Query: 177 G-GELTIYNVSLSDVGDYECVVKSAIG 202
L + + S+ G Y C +K+ G
Sbjct: 7532 NIATLQLGSPEASNSGKYICQIKNDAG 7558
Score = 52.4 bits (120), Expect = 5e-06
Identities = 134/595 (22%), Positives = 227/595 (38%), Gaps = 75/595 (12%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLI 113
P P TW KDNI + TE+ L II + +R D G + +N G +
Sbjct: 21731 PAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVR 21790
Query: 114 VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDT-AYLWNHNGLRIKDSSDLYVNKR 172
VL P + L P T V LH + P++D + + N+ + + + Y
Sbjct: 21791 VLDTPGPVLNLRP--TDITKDSVTLHWDL---PLIDGGSRITNYIVEKREATRKSYSTAT 21845
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKS----AIGRISSHVQ-LRIEGPPGPPGGVQILGI 227
K + T LS+ +Y V + IG + + ++ P PP + I+ I
Sbjct: 21846 TKCH--KCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDI 21903
Query: 228 QRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVS 286
+S+V+L W + G ITGY++ + + W +I V ++ V
Sbjct: 21904 TKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW----THITTVKGLE--------CVV 21951
Query: 287 TTLLPWAIYEFRIQAINILGPGQP--SAP--------SPQFSTSGDKPYEAPANVSGGGG 336
L Y F++ A+N G P S P P+ G Y+ G
Sbjct: 21952 RNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG--IYQKLVIAKAGDN 22009
Query: 337 KTGDLTITWTPLPT-SLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTY 395
++ + P PT + + G I + V F++ NI V S Y
Sbjct: 22010 IKVEIPVLGRPKPTVTWKKGDQI------LKQTQRVNFETTATSTILNINECVRSDSGPY 22063
Query: 396 FYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQS 455
T ++ G +V+TI D+P + +S + +W+P
Sbjct: 22064 PLTARNI---------VGEVGDVITI-QVHDIPGPPTGPIKFDEVSSDFVTFSWDP---- 22109
Query: 456 RERLRGKLIGHRLKYWKQENKEE--ECIYYLSRTT-RNWALIVGLQPDTYYYVKVMAFNS 512
E G I + + +Q + E + RTT + L GL+ Y +V A N
Sbjct: 22110 PENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLE----YQFRVKAQNR 22165
Query: 513 AGEGPE-SERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYKVR 570
G GP + + + PP + V A ++ + W +P ++ P+LGY V
Sbjct: 22166 YGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWH--EPLSDGGSPILGYHVE 22223
Query: 571 LWELDQDM-STANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
E + + T + +VP + ++ S + G +Y RV+A + G + S P+
Sbjct: 22224 RKERNGILWQTVSKALVP-GNIFKS--SGLTDGIAYEFRVIAENMAGKSKPSKPS 22275
Score = 52.4 bits (120), Expect = 5e-06
Identities = 70/285 (24%), Positives = 111/285 (38%), Gaps = 27/285 (9%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE---NGNLIIRQLSRDDEGVYTCV 98
G ++ +K + P P TW KD + I IT+ + +L +R +RD GVYT
Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE 28959
Query: 99 AKNQYGTDESRGRLIVLRAP-------RFLEKLPPRITAQVNSVVFLHCNADVDPILDTA 151
AKN G+ ++ ++ V P RF ++T ++ + C I++
Sbjct: 28960 AKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKR 29019
Query: 152 YLWNHNGLRIKDSSDLYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQL 210
I+D + IK I+G E Y +S V + + + +Q
Sbjct: 29020 ETSRLAWALIEDKCEAQSYTAIKLINGNE---YQFRVSAVNKFGVGRPLDSDPVVAQIQY 29076
Query: 211 RIEGPPGPPGGVQILGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIP 269
+ PG P I G +S+TL W S+ G I Y+L R ++ W + P
Sbjct: 29077 TVPDAPGIPEPSNITG---NSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRP 29133
Query: 270 NVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
+ R+ T L YEF + A N G G S S
Sbjct: 29134 --ISETRFK-------VTGLTEGNEYEFHVMAENAAGVGPASGIS 29169
Score = 52.0 bits (119), Expect = 7e-06
Identities = 73/308 (23%), Positives = 123/308 (39%), Gaps = 30/308 (9%)
Query: 22 LSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG 80
L+++PS K L TY + G ++ ++ P+P +W KD + + + E
Sbjct: 25235 LTIQPSLK---LPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETA 25291
Query: 81 N---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVF 137
L I++ ++DD G YT A N GT +IVL P PP + + V
Sbjct: 25292 TSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG-----PPVGPVRFDEVSA 25346
Query: 138 LHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYE--C 195
+P T N + K + + TI L +Y+
Sbjct: 25347 DFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRI 25406
Query: 196 VVKSAIGRIS--SHVQLRIEGP---PGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGY 249
++ G+ + + ++ P PGPPG + I + + ++W + N G I GY
Sbjct: 25407 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 25466
Query: 250 MLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQ 309
L + NS +V P ++ ++ +T L YEF++ A NI+G G+
Sbjct: 25467 HLEQKEK-NSILWVKLNKTP--IQDTKFK-------TTGLDEGLEYEFKVSAENIVGIGK 25516
Query: 310 PSAPSPQF 317
PS S F
Sbjct: 25517 PSKVSECF 25524
Score = 52.0 bits (119), Expect = 7e-06
Identities = 85/376 (22%), Positives = 147/376 (39%), Gaps = 35/376 (9%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFI--TENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGR 111
P P +W KD I I + I T+N L+ ++ R D G Y KN GT
Sbjct: 26744 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 26803
Query: 112 LIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDL--- 167
VL P PP ++N + C+ P D ++ + +++S L
Sbjct: 26804 CKVLDKPG-----PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 26858
Query: 168 YVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP---PGPPGGVQI 224
+++ ++T + V K +G V ++ P P PP ++I
Sbjct: 26859 ICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEI 26918
Query: 225 LGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRA 283
+ + S+TL W+ S+ G I+GY++ R + W +++ Y+ R +
Sbjct: 26919 TSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK-------PVYDLRVK- 26970
Query: 284 TVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG--GGGKTGDL 341
ST L YE+R+ A N G PS SP +P + GKT +
Sbjct: 26971 --STGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKT-TI 27027
Query: 342 TITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYD 401
TI W P P Y + ++++ + ++++ + G T IS Y
Sbjct: 27028 TIAWVK-PLFDGGAPITGYTVEYKKS-DDTDWKTSIQSLRGTEYT----ISGLTTGAEYV 27081
Query: 402 VKVQAFNDIGPGPESE 417
+V++ N +G S+
Sbjct: 27082 FRVKSVNKVGASDPSD 27097
Score = 51.6 bits (118), Expect = 9e-06
Identities = 51/221 (23%), Positives = 92/221 (41%), Gaps = 19/221 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA+N+ + + S+ + ++ P F K +E +V L + P TW
Sbjct: 5297 YMCEAQNEAGSDHCSS-IVIVKESPYFTKEFKPIEVLKEY--DVMLLAEVAGTPPFEITW 5353
Query: 62 KKDNIVIGAGGK--RFITEN-GNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KDN ++ +G K FI ++ +L I + D G Y C N+ G+ R+ + P
Sbjct: 5354 FKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 5413
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV--NKRIKID 176
F++K+ + + + F A + L W +KDS ++ N R+ +
Sbjct: 5414 SFIKKIESTSSLRGGTAAF---QATLKGSLPITVTW------LKDSDEITEDDNIRMTFE 5464
Query: 177 GGELTIY--NVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
++Y + + G Y C K+ G L ++ P
Sbjct: 5465 NNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEP 5505
Score = 51.6 bits (118), Expect = 9e-06
Identities = 49/207 (23%), Positives = 87/207 (42%), Gaps = 14/207 (6%)
Query: 76 ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ--VN 133
+ ++ + ++ L + E + A+NQ G + R L+ + LE PP I + +
Sbjct: 27353 VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE--PPEIDMKNFPS 27410
Query: 134 SVVFLHC--NADVD-PILDTAY---LWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSL 187
V++ N VD PI + +G+ +K + + N I + + +
Sbjct: 27411 HTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLK--ATMRFNTEITAENLTINLKESVT 27468
Query: 188 SDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG-VQILGIQRSSVTLEWTDSN-SNGRP 245
+D G YE ++ G + + + + PGPP G V I I SVTL+W G
Sbjct: 27469 ADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQ 27528
Query: 246 ITGYMLTGRTHWNSTWYVISENIPNVM 272
+T Y+L R + W +S + M
Sbjct: 27529 VTNYILLKRETSTAVWTEVSATVARTM 27555
Score = 51.2 bits (117), Expect = 1e-05
Identities = 100/477 (20%), Positives = 182/477 (38%), Gaps = 45/477 (9%)
Query: 162 KDSSDLYVNKRIKID--GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
K+ D RI + G +L I N + D G Y V++ G + V++ + PGPP
Sbjct: 18181 KEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPP 18240
Query: 220 GGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN 278
+++ I++ S L W + + G IT Y++ R ++ W +S
Sbjct: 18241 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSA-----------T 18289
Query: 279 GRKRATVSTTLLPWAIYEFRIQAINILGPGQ-PSAPSPQFSTSGDKPYEAPANVSGGGGK 337
+K++ + L Y FR+ A N G G P P + P P ++
Sbjct: 18290 SKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVD 18349
Query: 338 TGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY 397
++++ W P P Y + ++ G++ + K N+ V +
Sbjct: 18350 KTEVSLVWNK-PDRDGGSPITGYLVEYQEEGTQ---DWIKFKTVTNLECVVTGLQQG--- 18402
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
Y +V+A N +G G + I E ++ P V L V +
Sbjct: 18403 KTYRFRVKAENIVGLGLPDTTIPI---ECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPA 18459
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVG----LQPDTYYYVKVMAFNSA 513
+RG + W + E + + + T N++ ++ L+ DT Y ++ N+A
Sbjct: 18460 IIRG--VPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY-QITVSNAA 18516
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE--EPLLGYKVRL 571
G + + T P P +N+ P + + W QP ++ P++ Y V
Sbjct: 18517 GSKTVA---VHLTVLDVPGPPTGPINILDVTPEHMTISW---QPPKDDGGSPVINYIVEK 18570
Query: 572 WELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRM--SSPTIA 626
+ +D + K + I ++ G Y RV A + G G S+PT+A
Sbjct: 18571 QDTRKD---TWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVA 18624
Score = 51.2 bits (117), Expect = 1e-05
Identities = 55/240 (22%), Positives = 92/240 (38%), Gaps = 26/240 (10%)
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L+ P KL +T + + L P + A W + KD++DL + R+K
Sbjct: 19125 LQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVA--WTKD----KDATDLTRSPRVK 19178
Query: 175 ID----GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
ID + ++ SD G Y + G ++ + + PGP ++I+ +
Sbjct: 19179 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 19238
Query: 231 SVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
T+ W + G I Y+L W S + T T L
Sbjct: 19239 RCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATV-----------LTPGTTVTRL 19287
Query: 290 LPWAIYEFRIQAINILGPGQPSAPSPQFS-TSGDKPYEA-PANVSGGGGKTGDLTITWTP 347
+ Y FR++A N +G G P+ P + T DKP P V+ + ++T+ W P
Sbjct: 19288 IEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKE--EMTVVWNP 19345
Score = 51.2 bits (117), Expect = 1e-05
Identities = 44/161 (27%), Positives = 65/161 (40%), Gaps = 17/161 (10%)
Query: 161 IKDSSDLYVNKRIKIDGGE----LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
IK +L R++I + L++ + D G+Y K+ G S V +++ P
Sbjct: 23505 IKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRP 23564
Query: 217 GPP-GGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
GPP G V I G+ TL W G I Y++ R W V+ N+ +
Sbjct: 23565 GPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTL--- 23621
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSP 315
+ T LL Y FRI A+N G G+P P
Sbjct: 23622 --------SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEP 23654
Score = 50.8 bits (116), Expect = 2e-05
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 19/191 (9%)
Query: 188 SDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEW-TDSNSNGRPI 246
S G Y K+ G+ +++ ++++ PGPP +++ I R S L W + G I
Sbjct: 16811 SHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRI 16870
Query: 247 TGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILG 306
GY++ RT W ++ + + V LL Y FR++A N G
Sbjct: 16871 KGYVIEKRTIDGKAWTKVNPDCGST-----------TFVVPDLLSEQQYFFRVRAENRFG 16919
Query: 307 PGQPSAPSPQFSTSGDK--PYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKI-- 362
G P + Q +T+ D P + P + G + ++W P P + P HY +
Sbjct: 16920 IG-PPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKP-PKNDGGSPVTHYIVEC 16977
Query: 363 -FWRRNGSEVE 372
W G++ E
Sbjct: 16978 LAWDPTGTKKE 16988
Score = 50.4 bits (115), Expect = 2e-05
Identities = 93/426 (21%), Positives = 161/426 (37%), Gaps = 61/426 (14%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGR-PITGYMLTGRTHWNSTWYVISENIPNVME 273
PPGPP ++ +++ LEW NG I GY + + + W +E + ++
Sbjct: 15929 PPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKM---IK 15984
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKP--YEAPANV 331
V +Y ++ + A Y+ R+ A+N G G P P +P E +V
Sbjct: 15985 VRQYTVKE-------IREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSV 16037
Query: 332 SGG----GGKTGDL--TITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIG 385
GG GKT + +T P+PT + W + E++ +++ G
Sbjct: 16038 KGGIQIMAGKTLRIPAVVTGRPVPTKV-----------WTKEEGELDKDRVVIDNVGTKS 16086
Query: 386 TYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTAL 445
++ + + Y + A N G + V ++ D+P L + L
Sbjct: 16087 ELIIKDALRKDHGRY--VITATNSCGSKFAAARVEVF---DVPGPVLDLKPVVTNRKMCL 16141
Query: 446 NVTW-NPIDQSRERLRGKLIGH---RLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDT 501
+ W +P D + G +I ++ W+Q T R+ I GL
Sbjct: 16142 -LNWSDPEDDGGSEITGFIIERKDAKMHTWRQP----------IETERSKCDITGLLEGQ 16190
Query: 502 YYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS---VNVWAHDPTTLRVVWRYVQPT 558
Y +V+A N G GP E + P PP S + +T+ + W+ + +
Sbjct: 16191 EYKFRVIAKNKFGCGPPVE--IGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR-S 16247
Query: 559 NEEEPLLGYKVRLWELDQ-DMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGD 617
N P+ GY + D+ D N + P L + N+ + Y RV A + G+
Sbjct: 16248 NGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFL---VENLDEHQMYEFRVKAVNEIGE 16304
Query: 618 GRMSSP 623
S P
Sbjct: 16305 SEPSLP 16310
Score = 50.4 bits (115), Expect = 2e-05
Identities = 86/404 (21%), Positives = 152/404 (37%), Gaps = 34/404 (8%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
PGPP I+ ++S+TL W G I GY++ W +++ + V
Sbjct: 24847 PGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTG--LRV 24904
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGG 334
R+ K L Y+ R+ A+N +G G+ A S + + EAP
Sbjct: 24905 TRFEISK-------LTEHQEYKIRVCALNKVGLGE--ATSVPGTVKPEDKLEAPELDLDS 24955
Query: 335 GGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISST 394
+ G + + +I W R E + ++K N +
Sbjct: 24956 ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFT-DKVQIEKGVNYTQLSIDNCDR 25014
Query: 395 YFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNP-ID 453
Y +K++ + G +S VT+ D P PQ ++ + + + W P I
Sbjct: 25015 NDAGKYILKLENSS----GSKSAFVTV-KVLDTPG-PPQNLAVKEVRKDSAFLVWEPPII 25068
Query: 454 QSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSA 513
+++ +I K+E+ + S+ ++ + L YY +VMA N
Sbjct: 25069 DGGAKVKNYVID------KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 25122
Query: 514 GEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYKVRLW 572
G G E ++ P PP V + T+ ++W +P ++ +LGY V +
Sbjct: 25123 GVGVPVET-VDAVKAAEPPSPPGKVTLTDVSQTSASLMWE--KPEHDGGSRVLGYVVEM- 25178
Query: 573 ELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG 616
Q T +IV A ++ + G+ Y RV AY+ G
Sbjct: 25179 ---QPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKG 25219
Score = 50.0 bits (114), Expect = 3e-05
Identities = 54/205 (26%), Positives = 70/205 (34%), Gaps = 11/205 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + A L V PSF K P LE G NVT P W
Sbjct: 6797 YTCVAANVAGSDECRAVLTVQE-PPSFVKEPEPLEVL--PGKNVTFTSVIRGTPPFKVNW 6853
Query: 62 KKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+ + G + F L + + G YTCV N G RL V
Sbjct: 6854 FRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA 6913
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
FL++L S++ PI T W +G I S + K
Sbjct: 6914 AFLKRLSDHSVEPGKSIILESTYTGTLPISVT---WKKDGFNITTSEKCNIVTTEKT--C 6968
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGR 203
L I N + D G Y C +++ GR
Sbjct: 6969 ILEILNSTKRDAGQYSCEIENEAGR 6993
Score = 50.0 bits (114), Expect = 3e-05
Identities = 69/280 (24%), Positives = 109/280 (38%), Gaps = 26/280 (9%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQY 103
L+ P PT W KD + K + + NL+ + +R D G YT A N
Sbjct: 22408 LEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPG 22467
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNAD-VDPILDTAYLWNHNGLRIK 162
G + + VL P PP V V C P+ D +H ++ +
Sbjct: 22468 GFAKHIFNVKVLDRPG-----PPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKR 22522
Query: 163 DSSDL-YVNKRIKIDGGELTIYNVSLSD--VGDYECVVKSAIGR-ISSHVQLRIE--GPP 216
++S L + N ++ +L + + + + V K +G + S L + GPP
Sbjct: 22523 ETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPP 22582
Query: 217 GPPGGVQILGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIPNVMEVD 275
PP ++ I + S+ + W +S+ G I Y++ R W I N + ++
Sbjct: 22583 DPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRW--IKCNKKTLTDL- 22639
Query: 276 RYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSP 315
RY + L YEFRI A N G PS SP
Sbjct: 22640 RYK-------VSGLTEGHEYEFRIMAENAAGISAPSPTSP 22672
Score = 50.0 bits (114), Expect = 3e-05
Identities = 129/596 (21%), Positives = 231/596 (38%), Gaps = 70/596 (11%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
VT+K +PE P W+K ++ + +T + L+I ++R D G Y +N
Sbjct: 26056 VTIKGRPE----PEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNS 26111
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDT-AYLWNHNGLRIK 162
G+ + + VL +P L R + +SV + P++D A + N+ + +
Sbjct: 26112 GSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTL----SWEPPLIDGGAKITNYIVEKRE 26166
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS---AIGRISSHVQ-LRIEGPPGP 218
+ Y I N+ Y V+ S IG + + +++ PP P
Sbjct: 26167 TTRKAYATITNNCTKTTFRIENLQ-EGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLP 26225
Query: 219 PGGVQILGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRY 277
PG V ++ + R++ T++W S+ G ITGY++ +T + W ++ +E
Sbjct: 26226 PGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQ--VKTLE---- 26279
Query: 278 NGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS-------APSPQFSTSGDKPYEAPAN 330
AT+S L Y FR+ A+N G P A + S + P+ N
Sbjct: 26280 -----ATIS-GLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHT-FN 26332
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRN-GSEVEFQSLLLKKYG--NIGTY 387
V D+ P T G K R N S SL +K+ ++GTY
Sbjct: 26333 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 26392
Query: 388 VVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNV 447
+ +S++ + + + PGP P + + ++ +
Sbjct: 26393 ELCVSNSAGSITVPITIIVLD--RPGP-----------------PGPIRIDEVSCDSITI 26433
Query: 448 TWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
+WNP + G I + + K+E R IV L + Y +V
Sbjct: 26434 SWNPPEYD----GGCQISNYI-VEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRV 26488
Query: 508 MAFNSAGEGPESE-RYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLL 565
A N G+ SE + + +P PP + V +T+ V W+ P N+ ++
Sbjct: 26489 CAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQV--PVNDGGSRVI 26546
Query: 566 GYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
GY + E + + + I+ + +++ +S + G Y RV A + G G+ S
Sbjct: 26547 GYHLEYKERSSILWSKANKILIADTQMK--VSGLDEGLMYEYRVYAENIAGIGKCS 26600
Score = 49.6 bits (113), Expect = 4e-05
Identities = 55/222 (24%), Positives = 84/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+ KN + A L VL +K T G TL+CK P+ + W
Sbjct: 6608 YICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGE---TCTLECKVAGTPELSVEW 6664
Query: 62 KKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RA 117
KD ++ + K F + +L I + R D G YT +N G + V RA
Sbjct: 6665 YKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA 6724
Query: 118 --PRFLEKLPPRITAQVNSVVFLHCN-ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P F +L + + L C A PI + W H +I +
Sbjct: 6725 VPPSFTRRLK-NTGGVLGASCILECKVAGSSPI---SVAWFHEKTKIVSGAKYQTTFSDN 6780
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ L + ++ SD+G+Y CV + G L ++ PP
Sbjct: 6781 VC--TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 6820
Score = 49.6 bits (113), Expect = 4e-05
Identities = 86/416 (20%), Positives = 154/416 (37%), Gaps = 36/416 (8%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNG-RPITGYMLTGRTHWNSTWYVISENIPNVME 273
PP PP + + R + + W NG PI GY + W + N + +
Sbjct: 15211 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRV--NSRPIKD 15268
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
+ + V ++P Y R++A+N +G +PS S + D + ++
Sbjct: 15269 L-------KFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCKPTIDLET 15320
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYV-VHIS 392
+ P+P P + W ++G EV+ L K +I ++ V S
Sbjct: 15321 HDIIVIEGEKLSIPVPFRAVPVPTVS----WHKDGKEVKASDRLTMKNDHISAHLEVPKS 15376
Query: 393 STYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPI 452
Y + ++ N +G S V + +P + A ++ +TW P
Sbjct: 15377 VRADAGIYTITLE--NKLGSATASINVKVIG---LPGPCKD-IKASDITKSSCKLTWEPP 15430
Query: 453 DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
+ G I H + ++ + +W + L P+ Y+ +V A N
Sbjct: 15431 EFDG----GTPILHYVLERREAGRRTYIPVMSGENKLSWT-VKDLIPNGEYFFRVKAVNK 15485
Query: 513 AGEGP--ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYKV 569
G G E + + K P PP V V H+PT + + P + ++GY +
Sbjct: 15486 VGGGEYIELKNPVIAQDPKQPPDPPVDVEV--HNPTAEAMTITWKPPLYDGGSKIMGYII 15543
Query: 570 -RLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPT 624
++ + ++ N+ +VPI L + GK Y RV A + G S T
Sbjct: 15544 EKIAKGEERWKRCNEHLVPI---LTYTAKGLEEGKEYQFRVRAENAAGISEPSRAT 15596
Score = 49.2 bits (112), Expect = 5e-05
Identities = 57/234 (24%), Positives = 88/234 (37%), Gaps = 19/234 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKK-HPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C+ KN SA L VL +K P+ + T G L+C P+ +
Sbjct: 7549 YICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTT----GNPFALECVVTGTPELSAK 7604
Query: 61 WKKDNIVIGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV--- 114
W KD + A K FI + +L I D+G+Y+ KN G + V
Sbjct: 7605 WFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR 7664
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
+ P F+ KL + A + + V L C + W +G I +
Sbjct: 7665 IVPPSFIRKLKD-VNAILGASVVLECRVSGSAPISVG--WFQDGNEIVSGPKCQSSFSEN 7721
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG---PPGGVQIL 225
+ L++ + SD G Y CV + G L ++ PP P V++L
Sbjct: 7722 VCTLNLSL--LEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 7773
Score = 48.8 bits (111), Expect = 6e-05
Identities = 97/443 (21%), Positives = 160/443 (36%), Gaps = 42/443 (9%)
Query: 84 IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHC-NA 142
I L + +E + A+N+ G + R + + A + +PP N+ L +
Sbjct: 23035 ITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLV--IPPAFKLLFNTFTVLAGEDL 23092
Query: 143 DVD-PILDT---AYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVK 198
VD P + A W+ + + +K ++ VN + LTI + DVG Y +
Sbjct: 23093 KVDVPFIGRPTPAVTWHKDNVPLKQTTR--VNAESTENNSLLTIKDACREDVGHYVVKLT 23150
Query: 199 SAIGRISSHVQLRIEGPPGPP-GGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTH 256
++ G + + + PGPP G V++ + S+TL W G I Y++ R
Sbjct: 23151 NSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDT 23210
Query: 257 WNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAI-YEFRIQAINILGPGQPSAPSP 315
+TW ++S + R T+ L Y+FRI A N G P
Sbjct: 23211 STTTWQIVSATV------------ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEP 23258
Query: 316 QFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQS 375
+ K P + + W P S I Y + E S
Sbjct: 23259 TVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNE-PISDGGSRVIGYHL------ERKERNS 23311
Query: 376 LLLKKYGNIGTYVVHISSTYFY--TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQ 433
+L K +T Y+ +V A N +G G S+V Y A D P P
Sbjct: 23312 ILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD-PCDPPG 23370
Query: 434 LVSARSFNSTALNVTW-NPIDQSRERLRGKLIGHRLKYWKQENKEEECI-YYLSRTTRNW 491
A ++ + W P ++ G ++ K+E E + +
Sbjct: 23371 RPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE------KKELPEGRWMKASFTNIIDTH 23424
Query: 492 ALIVGLQPDTYYYVKVMAFNSAG 514
+ GL D Y +V+A N+AG
Sbjct: 23425 FEVTGLVEDHRYEFRVIARNAAG 23447
Score = 48.4 bits (110), Expect = 8e-05
Identities = 72/285 (25%), Positives = 114/285 (40%), Gaps = 25/285 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTFT 60
Y C A+N+ + S +L V ++ L T G T+ PE PK
Sbjct: 4921 YTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPK---- 4976
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLR- 116
W KD + A K I+ N+ ++ S + D G YT N+ G+ VL
Sbjct: 4977 WYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDR 5036
Query: 117 --APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
AP F + L + + VN L C + L W +G I +SD Y RI
Sbjct: 5037 DIAPFFTKPLR-NVDSVVNGTCRLDCK--IAGSLPMRVSWFKDGKEIA-ASDRY---RIA 5089
Query: 175 -IDG-GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG---PPGGVQILGIQR 229
++G L I V ++D G++ C +++G S L ++ PP PG +L
Sbjct: 5090 FVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVL--PG 5147
Query: 230 SSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
S+V L+ T S I + + Y+ E + + +E+
Sbjct: 5148 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLEL 5192
Score = 48.4 bits (110), Expect = 8e-05
Identities = 77/342 (22%), Positives = 133/342 (38%), Gaps = 41/342 (11%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
PP PP ++++ I +++ L+WT G PIT Y++ R W + + +
Sbjct: 15010 PPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDT-- 15067
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPG-----QPSAPSPQFSTSGDKPYE-A 327
+ TV T L ++Y FR+ A N +G + S + T+ PY A
Sbjct: 15068 --------KCTV-TPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALA 15118
Query: 328 PANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTY 387
+V+ + + W P P + P Y I + + +K G
Sbjct: 15119 VVDVT-----KRHVDLKWEP-PKNDGGRPIQRYVI-----EKKERLGTRWVKAGKTAGPD 15167
Query: 388 V-VHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED--MPQVAPQLVSARSFNSTA 444
++ T +V+A N+ G G SE I S ED P P +
Sbjct: 15168 CNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKH 15227
Query: 445 LNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIV--GLQPDTY 502
+ + W P +++ +IG+ ++ E+ + SR ++ V G+ PD
Sbjct: 15228 IAIAWKPPEKNG---GSPIIGYHVEMCPVGT--EKWMRVNSRPIKDLKFKVEEGVVPDKE 15282
Query: 503 YYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHD 544
Y ++V A N+ G SE E K P P ++++ HD
Sbjct: 15283 YVLRVRAVNAIGVSEPSE-ISENVVAKDPDCKP-TIDLETHD 15322
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 14/133 (10%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISEN-IPNVME 273
PG P ++ + + +T+ W G+ ITGY L + ++ W ++++ IP
Sbjct: 19323 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE--- 19379
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS-PQFSTSGDKPYEAPANVS 332
+R V LLP Y+FR++A N +G G+PS PS P + +P P N
Sbjct: 19380 -------RRMKVQN-LLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFR 19431
Query: 333 GGGGKTGDLTITW 345
+T+ W
Sbjct: 19432 VVDTTKHSITLGW 19444
Score = 47.6 bits (108), Expect = 1e-04
Identities = 55/240 (22%), Positives = 98/240 (40%), Gaps = 12/240 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + S ++ V+ PSF K LE G N L+C+ +W
Sbjct: 4735 YSCEAVNDVGSDSCSTEI-VIKEPPSFIK-TLEPADI-VRGTNALLQCEVSGTGPFEISW 4791
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQL---SRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I + K + +L+ ++ + D G Y CV N+ G ++ P
Sbjct: 4792 FKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPP 4851
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
F++K+ I +V +PI T W I++ + ++ +
Sbjct: 4852 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVT---WMKGQEVIREDGKIKMSFSNGV--A 4906
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSS-VTLEWT 237
L I +V +S G Y C+ ++ G +S +L ++ P +++ + TLE+T
Sbjct: 4907 VLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYT 4966
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 6/124 (4%)
Query: 4 CEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKK 63
CEA+N ++ S ++ ++ P F P +ET + V+L+C+ P W K
Sbjct: 6423 CEAQNPAGSTSCSTKV-IVKEPPVFSSFPPIVETL--KNAEVSLECELSGTPPFEVVWYK 6479
Query: 64 DNIVIGAGGK-RFITENGNLIIRQLSRD--DEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
D + + K + ++N + I L+ D D G Y C A+N+ G+D + + PRF
Sbjct: 6480 DKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRF 6539
Query: 121 LEKL 124
+ KL
Sbjct: 6540 VSKL 6543
Score = 46.8 bits (106), Expect = 2e-04
Identities = 32/110 (29%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 162 KDSSDLYVNKRIKIDGGE----LTIYNVSLSDVGDYECVVKSAIGRI-SSHVQLRIEGPP 216
KD +L + R I+ + LTI V+ +D G Y +++ +G SS V +++ P
Sbjct: 28234 KDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTP 28293
Query: 217 GPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVIS 265
+Q+ + R +VTL W G PI Y++ R TW V+S
Sbjct: 28294 AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVS 28343
Score = 46.4 bits (105), Expect = 3e-04
Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT-ENG--NLIIRQLSRDDEGVYTC 97
EG +VTL+C P PT TW +++ I + IT ++G L+IR+ +D G +TC
Sbjct: 956 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 1015
Query: 98 VAKNQYGTDESRGRLIVLRAPRFLEKLPPRIT 129
A N+ GT + L V + F EK +T
Sbjct: 1016 SAVNEAGTVSTSCYLAVQVSEEF-EKETTAVT 1046
Score = 46.4 bits (105), Expect = 3e-04
Identities = 50/233 (21%), Positives = 91/233 (39%), Gaps = 26/233 (11%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLK--PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPT 58
+Y C+ N ++ ++ + + K P F +H + SEG V L C + +
Sbjct: 9246 LYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTV--SEGEYVQLSCHVQGSEPIR 9303
Query: 59 FTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W K I + F + L +R +++ D G Y C A N G+D ++ ++ +
Sbjct: 9304 IQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 9363
Query: 116 RAPR--------------FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR- 160
P F P I + DPI + W R
Sbjct: 9364 DKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVK--WTKGKWRQ 9421
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
+ +++++ K D +L I + + +D G Y CV + G I S+V L+++
Sbjct: 9422 LNQGGRVFIHQ--KGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVD 9472
Score = 46.0 bits (104), Expect = 4e-04
Identities = 44/176 (25%), Positives = 67/176 (38%), Gaps = 20/176 (11%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGR 111
P+P +W K+ ++ G K +G L++ + +D VYTC AKN YG +
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325
Query: 112 LI-----VLRAPRFLEKLPPRITAQVNSVVF-------LHCNADVDPILDTAYLWNHNGL 159
L V+ + + PP I + V C D W
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG---TDLKVSWYSKDK 3382
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
+IK S + D +L I D G Y V +A+G++SS L +E P
Sbjct: 3383 KIKPSR--FFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436
Score = 46.0 bits (104), Expect = 4e-04
Identities = 52/222 (23%), Positives = 83/222 (37%), Gaps = 12/222 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A+N++ + ++ L P F L E L+ E A W
Sbjct: 6514 YHCKAQNEVGSDTCVCTVK-LKEPPRFVSKLNSLTVVAGEPAE--LQASIEGAQPIFVQW 6570
Query: 62 --KKDNIVIGAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+K+ ++ + R F+ L + + G Y C KN G +E+ L+VL
Sbjct: 6571 LKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEP 6630
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+EK P +T V L C P L W +G + S + KI
Sbjct: 6631 AVIVEKAGP-MTVTVGETCTLECKVAGTPELSVE--WYKDGKLLTSSQKHKFSFYNKI-- 6685
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
L I +V D G Y V++ +G+ S + + PP
Sbjct: 6686 SSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPP 6727
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/369 (20%), Positives = 138/369 (37%), Gaps = 29/369 (7%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHV-QLRI 212
W+ +G ++ ++ L + +I L + + D G Y + G + H+ +++
Sbjct: 22422 WSKDGKELEGTAKLEI--KIADFSTNLVNKDSTRRDSGAYTLTATNP-GGFAKHIFNVKV 22478
Query: 213 EGPPGPPGG-VQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPN 270
PGPP G + + + L W + G I Y++ R W N+ +
Sbjct: 22479 LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAW----TNVAS 22534
Query: 271 VMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN 330
++V + T LL Y FR+ A+N G G+P P + + P + P N
Sbjct: 22535 EVQVTKLK-------VTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN 22587
Query: 331 VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
+ + W P S I+Y I RR+ + + K ++ V
Sbjct: 22588 PEVTTITKDSMVVCWGH-PDSDGGSEIINY-IVERRDKAGQRWIKCNKKTLTDLRYKVSG 22645
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED--MPQVAPQLVSARSFNSTALNVT 448
++ + Y+ ++ A N G S Y A D P + +++++
Sbjct: 22646 LTEGH---EYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIA 22702
Query: 449 WN-PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKV 507
WN PI + G ++ L E E + + + I GL + Y +++
Sbjct: 22703 WNKPIYDGGSEITGYMVEIAL----PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRI 22758
Query: 508 MAFNSAGEG 516
A NS G G
Sbjct: 22759 YAMNSEGLG 22767
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L + NV+ D G Y V+++ G S+ V +R+ PGPP +++ + ++SVTL W
Sbjct: 22843 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPP 22902
Query: 240 -NSNGRPITGYMLTGRTHWNSTWYVISEN 267
G I Y++ R + ++ N
Sbjct: 22903 LLDGGSKIKNYIVEKRESTRKAYSTVATN 22931
Score = 45.6 bits (103), Expect = 6e-04
Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-----NLIIRQLSRDDEGVY 95
EGG+V C+ PKP WKK + + G + ++ N L+I DD G Y
Sbjct: 1095 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1154
Query: 96 TCVAKNQYGTDESRGRLI 113
T V +N++G + L+
Sbjct: 1155 TIVVRNKHGETSASASLL 1172
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/167 (25%), Positives = 71/167 (42%), Gaps = 13/167 (7%)
Query: 465 GHRLKYWKQENKEEECIYYLSRTTRNWAL---IVGLQPDTYYYVKVMAFNSAGEGPESER 521
G R+ + E +E Y + TT+ + GL Y+ +VMA N G G +E
Sbjct: 21823 GSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTET 21882
Query: 522 YLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYKVRLWELDQDMST 580
+AP PP S+N+ +T+ + W +P ++ + GY + D T
Sbjct: 21883 TEPVKASEAP-SPPDSLNIMDITKSTVSLAW--PKPKHDGGSKITGYVIEAQRKGSDQWT 21939
Query: 581 ANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG--RMSSPTI 625
T+ LE + N+ G+ Y +V+A ++ G R S P I
Sbjct: 21940 HITTV----KGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVI 21982
Score = 44.4 bits (100), Expect = 0.001
Identities = 92/420 (21%), Positives = 162/420 (38%), Gaps = 43/420 (10%)
Query: 210 LRIEGPPGPPGGVQILGIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENI 268
+++ P PPG + + + R+SV+L WT + G I Y++ + + W
Sbjct: 24052 IKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW------- 24104
Query: 269 PNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSG--DKPYE 326
E R + V T L Y FR+ A+N G P + + +P
Sbjct: 24105 ---SECARV--KSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV 24159
Query: 327 APANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGT 386
PA S DL I +P S + P I W ++G ++ Q+ + ++
Sbjct: 24160 KPAFSSYSVQVGQDLKI---EVPISGRPKP----TITWTKDGLPLK-QTTRINVTDSLDL 24211
Query: 387 YVVHISSTYFYTPYDVKVQAFNDIGPGPES-EVVTIYSAEDMPQVAPQLVSARSFNSTAL 445
+ I T+ + N +G S E+VT+ D P V ++ ++
Sbjct: 24212 TTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTL----DKPDPPKGPVKFDDVSAESI 24267
Query: 446 NVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYV 505
++WNP + G I + + K++ + R + L+ T Y
Sbjct: 24268 TLSWNPPLYT----GGCQITNYI-VQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQF 24322
Query: 506 KVMAFNSAGE--GPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNE-EE 562
++ A N G+ ES+ + + K P PP + A ++ + W +P N
Sbjct: 24323 RIFAENRYGQSFALESDPIVAQYPYKEP-GPPGTPFATAISKDSMVIQWH--EPVNNGGS 24379
Query: 563 PLLGYKVRLWELDQDMST-ANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMS 621
P++GY + E + + T N TI+ H + N+ G Y RV A + G G+ S
Sbjct: 24380 PVIGYHLERKERNSILWTKVNKTII---HDTQFKAQNLEEGIEYEFRVYAENIVGVGKAS 24436
Score = 44.4 bits (100), Expect = 0.001
Identities = 54/279 (19%), Positives = 111/279 (39%), Gaps = 31/279 (11%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG----NLIIRQLSRDDEGVYTC 97
GG+ + + P P TW ++ G + E G L I R+D G Y
Sbjct: 24966 GGSARIHIPFKGRPTPEITWSREE---GEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYIL 25022
Query: 98 VAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDT-AYLWNH 156
+N G+ + + VL P + L + + ++ + PI+D A + N+
Sbjct: 25023 KLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWE-----PPIIDGGAKVKNY 25077
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG---RISSHVQLRIE 213
+ + + Y N K + N++ + + + ++ G + + ++
Sbjct: 25078 VIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAA 25137
Query: 214 GPPGPPGGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISEN-IPNV 271
PP PPG V + + ++S +L W + G + GY++ + W +++E+ + N
Sbjct: 25138 EPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNA 25197
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQP 310
+ +G++ Y+FR++A N G P
Sbjct: 25198 VVTGLSSGQE-------------YQFRVKAYNEKGKSDP 25223
Score = 44.0 bits (99), Expect = 0.002
Identities = 95/425 (22%), Positives = 156/425 (36%), Gaps = 42/425 (9%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNV-ME 273
P PP V+ +S+ L W N G I GY++ + W E + ME
Sbjct: 14515 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 14574
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
V K W Y +R++A+N G +PS P+ + + EAP
Sbjct: 14575 VTGLEEGK----------W--YAYRVKALNRQGASKPSRPTEEIQAVDTQ--EAPEIFLD 14620
Query: 334 GGGKTGDLTI---TWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVH 390
G LT+ T LP ++ P KI W + ++ + + + V
Sbjct: 14621 VKLLAG-LTVKAGTKIELPATVTGKP--EPKITWTKADMILKQDKRITIENVPKKSTVTI 14677
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ S T + ++A N G + V + D P P + + +TWN
Sbjct: 14678 VDSKRSDTGTYI-IEAVNVCG---RATAVVEVNVLDKPG-PPAAFDITDVTNESCLLTWN 14732
Query: 451 PI-DQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL-IVGLQPDTYYYVKVM 508
P D ++ ++ R + E + LS T ++ L P+ Y +V
Sbjct: 14733 PPRDDGGSKITNYVVERRAT-------DSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVA 14785
Query: 509 AFNSAGEG-PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEE-EPLLG 566
A N G G P + ++ P PP + D T V + +P ++ P+ G
Sbjct: 14786 AENMYGVGEPVQASPITAKYQFDPPGPPTRLE--PSDITKDAVTLTWCEPDDDGGSPITG 14843
Query: 567 YKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
Y V + D D + + P++ + + K Y RVLA + G G+ S T
Sbjct: 14844 YWVERLDPDTDKWVRCNKM-PVKDTTYR-VKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 14901
Query: 627 FQIGD 631
I D
Sbjct: 14902 ILIKD 14906
Score = 43.6 bits (98), Expect = 0.002
Identities = 24/80 (30%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK--DNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCV 98
G + ++ P PT WKK D +V + ++ + LII+ ++R D G Y+
Sbjct: 19840 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLT 19899
Query: 99 AKNQYGTDESRGRLIVLRAP 118
A+N GTD + +++V+ AP
Sbjct: 19900 AENSSGTDTQKIKVVVMDAP 19919
Score = 43.6 bits (98), Expect = 0.002
Identities = 68/272 (25%), Positives = 103/272 (37%), Gaps = 28/272 (10%)
Query: 55 PKPTFTWKKDNIVIGAGGK--RFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGR 111
P P TW KDN+ + + TEN +L+ I+ R+D G Y N G
Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLN 23161
Query: 112 LIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNK 171
+IVL P PP +++ V P +N + K + +
Sbjct: 23162 VIVLDKPG-----PPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQ 23216
Query: 172 RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP--------PGPPGGVQ 223
+ TI L +Y+ + +A R L E PGPPG
Sbjct: 23217 IVSATVARTTIKACRLKTGCEYQFRI-AAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPV 23275
Query: 224 ILGIQRSSVTLEWTDSNSN-GRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKR 282
+ R S+ ++W + S+ G + GY L R NS +V P + ++
Sbjct: 23276 VTLSSRDSMEVQWNEPISDGGSRVIGYHLE-RKERNSILWVKLNKTP--IPQTKFK---- 23328
Query: 283 ATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
+T L YEFR+ A NI+G G+PS S
Sbjct: 23329 ---TTGLEEGVEYEFRVSAENIVGIGKPSKVS 23357
Score = 42.7 bits (96), Expect = 0.004
Identities = 75/343 (21%), Positives = 134/343 (39%), Gaps = 40/343 (11%)
Query: 30 KHPLELETYGS---EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE---NGNLI 83
K ++LET+ EG +++ A P PT +W KD + A + + + +L
Sbjct: 15313 KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLE 15372
Query: 84 IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPR-ITAQVNSVVFLHCNA 142
+ + R D G+YT +N+ G+ + + V+ P + + IT + +
Sbjct: 15373 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 15432
Query: 143 D-VDPILDTAYLWNHNGLR-----IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECV 196
D PIL G R + + L + I GE +++ VG E +
Sbjct: 15433 DGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYI 15492
Query: 197 -VKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGR 254
+K+ + + + PP PP V++ ++T+ W G I GY++
Sbjct: 15493 ELKNPV------IAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKI 15546
Query: 255 THWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
W +E++ ++ Y + L Y+FR++A N G +PS +
Sbjct: 15547 AKGEERWKRCNEHLVPIL---TYTAK-------GLEEGKEYQFRVRAENAAGISEPSRAT 15596
Query: 315 PQFSTSGDKPYEAP-------ANVSGGGGKTGDLTITWTPLPT 350
P T P +AP V G D +I+ +P PT
Sbjct: 15597 P--PTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPT 15637
Score = 42.3 bits (95), Expect = 0.005
Identities = 32/95 (33%), Positives = 42/95 (44%), Gaps = 9/95 (9%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITE-NGNLIIRQLSRDDEGVYT 96
EG VT CK P P W KD I G + F+ + +L I + +DEG+YT
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 97 CVAKNQYGTDESRGRLIV-----LRAPRFLEKLPP 126
A N G G+L V L AP ++ L P
Sbjct: 1364 AFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEP 1398
Score = 42.3 bits (95), Expect = 0.005
Identities = 50/189 (26%), Positives = 79/189 (41%), Gaps = 14/189 (7%)
Query: 18 QLRVLSLKPSFKKHPLELETYGSE--GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-R 74
QL+ + LK F K ++ SE G + +C + T TW KD I K R
Sbjct: 12036 QLKAVPLK--FVKEIKDIILTESEFVGSSAIFECLVSPSTAIT-TWMKDGSNIRESPKHR 12092
Query: 75 FITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP-RFLEKLPPRITAQ 131
FI + + L I + D G YTCV + S +L+V P RF++ L +T
Sbjct: 12093 FIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVV 12152
Query: 132 VNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVG 191
++L C + + +W +G + + V I + LTI + +D G
Sbjct: 12153 KGQPLYLSCELN----KERDVVWRKDGKIVVEKPGRIVPGVIGLMRA-LTINDADDTDAG 12207
Query: 192 DYECVVKSA 200
Y V++A
Sbjct: 12208 TYTVTVENA 12216
Score = 42.3 bits (95), Expect = 0.005
Identities = 37/169 (21%), Positives = 72/169 (42%), Gaps = 16/169 (9%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDS 239
L + NV+ D G Y ++++ G S+ V +R+ P PP +++ I + SV++ W
Sbjct: 23925 LVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPP 23984
Query: 240 -NSNGRPITGYMLTGRTHWNSTWYVISENI-PNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
G I Y++ R ++ + N N ++D+ L Y F
Sbjct: 23985 LLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQ------------LQEGCSYYF 24032
Query: 298 RIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
R+ A N G G P+ + + + P + P ++ ++++WT
Sbjct: 24033 RVTAENEYGIGLPAQTADPIKVA-EVP-QPPGKITVDDVTRNSVSLSWT 24079
Score = 41.9 bits (94), Expect = 0.007
Identities = 46/187 (24%), Positives = 76/187 (40%), Gaps = 13/187 (6%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAG---GKRFITENGN--LIIRQLSRDDEGVY 95
EG T + P P +W +D VI G + +G L I +++ + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 96 TCVAKNQYGTDESRGRLIV---LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAY 152
+ A N G S L+V P F+++L +T + S V L V I
Sbjct: 79 SLKATNGSGQATSTAELLVKAETAPPNFVQRLQS-MTVRQGSQVRLQVR--VTGIPTPVV 135
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ +G I+ S D +++ + D L I D G Y +++GR +S +L +
Sbjct: 136 KFYRDGAEIQSSLDFQISQ--EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Query: 213 EGPPGPP 219
+G P
Sbjct: 194 QGEEEVP 200
Score = 41.9 bits (94), Expect = 0.007
Identities = 54/226 (23%), Positives = 90/226 (39%), Gaps = 21/226 (9%)
Query: 400 YDVKVQAFNDIGPGPE--SEVVTIYSAEDMP-QVAPQLVSARSFNSTALNVTWNP-IDQS 455
Y ++ A N G G +E + D P + P ++S + + V+W P D
Sbjct: 20385 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVIS--NITKDHMTVSWKPPADDG 20442
Query: 456 RERLRGKLIGHRLKY---WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNS 512
+ G L+ R W + N++ + RT + GLQ T Y +V A N
Sbjct: 20443 GSPITGYLLEKRETQAVNWTKVNRKP----IIERTLK----ATGLQEGTEYEFRVTAINK 20494
Query: 513 AGEGPESERYLERTFRKAPQKPPA-SVNVWAHDPTTLRVVWRYVQPTNE-EEPLLGYKVR 570
AG G S+ + + + PQ PPA +D T V + +P + P++GY V
Sbjct: 20495 AGPGKPSDA-SKAAYARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVE 20553
Query: 571 LWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG 616
+ D D + + K ++ ++ Y RV A + G
Sbjct: 20554 VKRADSD-NWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG 20598
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/280 (20%), Positives = 110/280 (39%), Gaps = 25/280 (8%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAK 100
GG + + P PT TW + + T + +++I+ R +GVY+ +AK
Sbjct: 17466 GGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAK 17525
Query: 101 NQYGTDESRGRLIVLRAPRFLEK--LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
N+ G + + VL P + L +T + + + D + +
Sbjct: 17526 NEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRES 17585
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGR---ISSHVQLRIEGP 215
R + Y R T+ + + +++IG + + L I P
Sbjct: 17586 DRRAWTPVTYTVTR-----QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 17640
Query: 216 ---PGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISENIPNV 271
P P +++ + +++VTL W G I Y+L R ++ ++ + N+
Sbjct: 17641 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTND--NL 17698
Query: 272 MEVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS 311
+ ++ TV L YE+R+ A+NI+G G+PS
Sbjct: 17699 LS-------RKYTVK-GLKEGDTYEYRVSAVNIVGQGKPS 17730
Score = 41.1 bits (92), Expect = 0.012
Identities = 62/245 (25%), Positives = 95/245 (38%), Gaps = 29/245 (11%)
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQIL-GIQRSSVTLEW-T 237
+ I N S G Y + K+ G + + + PGP G + + S L W +
Sbjct: 17507 MVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFS 17566
Query: 238 DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
+ G PIT Y++ R W ++ + R+ ATV L+ Y F
Sbjct: 17567 PEDDGGSPITNYVIEKRESDRRAWTPVTYTVT----------RQNATVQ-GLIQGKAYFF 17615
Query: 298 RIQAINILGPGQPSAPSPQFSTSGD--KPYEAPANVSGGGGKTGDLTITWTPLPTSLQNG 355
RI A N +G G P + + + E P ++ +T+TW P P
Sbjct: 17616 RIAAENSIGMG-PFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNP-PKYDGGS 17673
Query: 356 PGIHYKIFWRRNGSE----VEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIG 411
I+Y + R G+E V +LL +KY G + TY Y +V A N +G
Sbjct: 17674 EIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKG---LKEGDTYEY-----RVSAVNIVG 17725
Query: 412 PGPES 416
G S
Sbjct: 17726 QGKPS 17730
Score = 41.1 bits (92), Expect = 0.012
Identities = 97/418 (23%), Positives = 160/418 (38%), Gaps = 62/418 (14%)
Query: 216 PGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
PGPP +++ I RSSV L W+ G I GY++ W + + P +
Sbjct: 23765 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP--PTGINK 23822
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS-APSPQFSTSGDKPYEAP----- 328
K LL Y FRI AIN G G+ + P P ++ EAP
Sbjct: 23823 TNIEVEK-------LLEKHEYNFRICAINKAGVGEHADVPGPIIV---EEKLEAPDIDLD 23872
Query: 329 ------ANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYG 382
N+ GG + I P P ++ W + E+ + ++
Sbjct: 23873 LELRKIINIRAGGSLRLFVPIKGRPTP-----------EVKWGKVDGEIR-DAAIIDVTS 23920
Query: 383 NIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNS 442
+ + V+ + Y Y + ++ + G +S VT+ D P P +
Sbjct: 23921 SFTSLVLDNVNRYDSGKYTLTLENSS----GTKSAFVTV-RVLDTPS-PPVNLKVTEITK 23974
Query: 443 TALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTT---RNWALIVGLQP 499
++++TW P L G G ++K + E +E Y + T +N I LQ
Sbjct: 23975 DSVSITWEP-----PLLDG---GSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQE 24026
Query: 500 DTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTN 559
YY +V A N G G ++ + PQ PP + V D T V + +P +
Sbjct: 24027 GCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQ-PPGKITV--DDVTRNSVSLSWTKPEH 24083
Query: 560 E-EEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGG 616
+ ++ Y V E+ S ++ L+A I+N+ G+ Y RV+A + G
Sbjct: 24084 DGGSKIIQYIV---EMQAKHSEKWSECARVK-SLQAVITNLTQGEEYLFRVVAVNEKG 24137
Score = 40.7 bits (91), Expect = 0.016
Identities = 33/113 (29%), Positives = 48/113 (42%), Gaps = 5/113 (4%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNI-VIGAGGKRFITENGN---LIIRQLSRDDEGVYT 96
E T K P P W K + GG+ FI + G+ L IR ++ D G+Y
Sbjct: 9394 EKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYR 9453
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILD 149
CVA N++G ES L V + EK+ + A + L A + +D
Sbjct: 9454 CVAFNEHGEIESNVNLQVDERKK-QEKIEGDLRAMLKKTPILKKGAGEEEEID 9505
Score = 40.3 bits (90), Expect = 0.022
Identities = 26/113 (23%), Positives = 49/113 (43%), Gaps = 3/113 (2%)
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
W+ + ++D L + K D L NV+ D G Y ++++ G+ + +++
Sbjct: 20654 WSKPNVNLRDRIGLDI-KSTDFDTF-LRCENVNKYDAGKYILTLENSCGKKEYTIVVKVL 20711
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVIS 265
PGPP V + I + S + W G PI Y++ R +W ++
Sbjct: 20712 DTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVT 20764
Score = 40.3 bits (90), Expect = 0.022
Identities = 27/98 (27%), Positives = 42/98 (42%), Gaps = 10/98 (10%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSN-SNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
PPGPP + + S +L W + G ITGY++ + + W I + +
Sbjct: 21599 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW--IKDTTGTALR 21656
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPS 311
+ ++ V L Y FRI AIN G G+P+
Sbjct: 21657 ITQF-------VVPDLQTKEKYNFRISAINDAGVGEPA 21687
Score = 39.9 bits (89), Expect = 0.029
Identities = 22/65 (33%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
Query: 55 PKPTFTWKKDNIVIGAGGKRFITEN----GNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
P PT TW K+N + I N G I+ R+D G+Y C A+N G
Sbjct: 3648 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3707
Query: 111 RLIVL 115
L+VL
Sbjct: 3708 ELLVL 3712
Score = 39.5 bits (88), Expect = 0.038
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 33 LELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFI--TENGNLI-IRQLSR 89
L G +V + + P PT TW+KD +G+ + I T++ +L+ I Q++R
Sbjct: 28204 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 28263
Query: 90 DDEGVYTCVAKNQYGTDESRGRLI-VLRAPRFLEKL 124
+D G Y +N G +S + VL P +KL
Sbjct: 28264 NDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 28299
Score = 39.1 bits (87), Expect = 0.050
Identities = 42/188 (22%), Positives = 74/188 (39%), Gaps = 13/188 (6%)
Query: 31 HPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN---LIIRQL 87
H ++T EG V L A + W +N ++ + K ++ N L+I ++
Sbjct: 4292 HTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKV 4349
Query: 88 SRDD-EGVYTCVAKNQYGTDESRGRLIVLR--APRFLEKLPPRITAQVNSVVFLHCNADV 144
+ +D +G Y C A N G + +L V++ AP K+ P + + + C
Sbjct: 4350 NTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEP-LEVALGHLAKFTCEIQS 4408
Query: 145 DPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRI 204
P + + W G I +S + I L I + D G+Y C + G +
Sbjct: 4409 AP--NVRFQWFKAGREIYESDKCSIRSSKYI--SSLEILRTQVVDCGEYTCKASNEYGSV 4464
Query: 205 SSHVQLRI 212
S L +
Sbjct: 4465 SCTATLTV 4472
Score = 38.7 bits (86), Expect = 0.066
Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 22/227 (9%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDM-PQVAPQLVSARSFNSTALNVTWNPIDQSRER 458
Y +V+A N GPGP + + + P AP S ++ V WN +
Sbjct: 15800 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 15859
Query: 459 LRGKLIGHR---LKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGE 515
+ G + R +W + NK L+ N + GL Y +V A N+AG
Sbjct: 15860 ILGYWLEKREVNSTHWSRVNKS-----LLNALKAN---VDGLLEGLTYVFRVCAENAAGP 15911
Query: 516 GPESERYLERTFRKAPQKP-PASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWEL 574
G S +T P P V TT+ + W N ++GY V
Sbjct: 15912 GKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWE-PPAFNGGGEIVGYFV----- 15965
Query: 575 DQDMSTANDTIVPIEH--KLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
D+ + N+ E K+ Y + I G Y LRV A + G+G
Sbjct: 15966 DKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 16012
Score = 38.7 bits (86), Expect = 0.066
Identities = 44/196 (22%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTD 238
EL I +D G Y K++ G + + PGP +++ + + + T+ W +
Sbjct: 18892 ELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWEN 18951
Query: 239 SNSN-GRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLLPWAIYEF 297
N G IT +++ R W +++ ++ + + LL Y F
Sbjct: 18952 PLDNGGSEITNFIVEYRKPNQKGWSIVASDV------------TKRLIKANLLANNEYYF 18999
Query: 298 RIQAINILGPGQP-SAPSPQFSTSG-DKPYEAPANVS-GGGGKTGDLTITWTPLPTSLQN 354
R+ A N +G G +P + + D+P E P N+ GKT + + W P
Sbjct: 19000 RVCAENKVGVGPTIETKTPILAINPIDRPGE-PENLHIADKGKT-FVYLKWR-RPDYDGG 19056
Query: 355 GPGIHYKIFWRRNGSE 370
P + Y + R GS+
Sbjct: 19057 SPNLSYHVERRLKGSD 19072
Score = 38.7 bits (86), Expect = 0.066
Identities = 56/238 (23%), Positives = 94/238 (39%), Gaps = 31/238 (13%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PPG +++ + +S+V+L W + G I GY + W V P+ +
Sbjct: 20116 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKW-VRCNTAPHQIP 20174
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRI---QAINILGPGQPSAP--------SPQFSTSGD 322
+ Y +T L A Y+FR A+NI P +PS P P+ S
Sbjct: 20175 QEEY-------TATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-- 20225
Query: 323 KPYEAPANVSGGGGKTGDLTITWTPLPTS--LQNG----PGIHYKIFWRRNGSEVEFQSL 376
++ V G D T+ P+PT ++G P K+ +RN +E S+
Sbjct: 20226 VAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSV 20285
Query: 377 LLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQL 434
K + G Y + ++ +K++ + GP ++ +YS M P L
Sbjct: 20286 NRK---DSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPL 20340
Score = 38.3 bits (85), Expect = 0.087
Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENG--N 81
KP FKK L + + P P W D + A + R I E G +
Sbjct: 1702 KPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCS 1761
Query: 82 LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
L D G+ TC A N+YGTD + LIV
Sbjct: 1762 LDYGVAYSRDSGIITCRATNKYGTDHTSATLIV 1794
Score = 38.3 bits (85), Expect = 0.087
Identities = 48/224 (21%), Positives = 82/224 (36%), Gaps = 13/224 (5%)
Query: 400 YDVKVQAFNDIGPGPESEVVTIYSAEDM-PQVAPQLVSARSFNSTALNVTWN-PIDQSRE 457
Y +V A N G G + + + P P+ + V+W P+D
Sbjct: 21469 YIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGS 21528
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWAL-IVGLQPDTYYYVKVMAFNSAGEG 516
+ G + R E K + + + + GLQ + Y +V A N AG G
Sbjct: 21529 EITGYHVERR------EKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 21582
Query: 517 PESERYLERTFRKA--PQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWEL 574
P SE + A P PP++ +V + + W E + GY V ++
Sbjct: 21583 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLE-ITGYVVEHQKV 21641
Query: 575 DQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGDG 618
D + DT + + ++ + YN R+ A ++ G G
Sbjct: 21642 G-DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 21684
Score = 38.3 bits (85), Expect = 0.087
Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 12/101 (11%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDS-NSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
P PPG + + R ++TL+W G I GY + R N W + N +V E
Sbjct: 28781 PVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKR-QGNERW--VRCNFTDVSE 28837
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
+ TV T L P YEFRI A N +G P + S
Sbjct: 28838 C-------QYTV-TGLSPGDRYEFRIIARNAVGTISPPSQS 28870
Score = 37.5 bits (83), Expect = 0.15
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 40 SEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGK-RFITENGN--LIIRQLSRDDEGVYT 96
S G TL PKP W + +++ +F+ + + LII +DEG YT
Sbjct: 3515 SMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYT 3574
Query: 97 CVAKNQYG 104
C+A N YG
Sbjct: 3575 CMASNDYG 3582
Score = 37.5 bits (83), Expect = 0.15
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
PP PP ++I I +++V L W N G P+T Y++ W+ T +
Sbjct: 16938 PPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLA-WDPT----GTKKEAWRQ 16992
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSA 312
++ + + L+ YEFR++A+N G +PSA
Sbjct: 16993 CNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSA 17031
Score = 37.1 bits (82), Expect = 0.20
Identities = 48/189 (25%), Positives = 76/189 (40%), Gaps = 22/189 (11%)
Query: 216 PGPPGGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P PPG + ++ + R+SV+L W + G I GY++ +T + W + ++V
Sbjct: 22976 PLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA-----TVKV 23030
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAIN---ILGPGQPSAPSPQFSTSGDKPYEAPAN- 330
AT+ T L+ Y FR+ A N I P Q S P ++ N
Sbjct: 23031 ------TEATI-TGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNT 23083
Query: 331 --VSGGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYG---NIG 385
V G D+ P P + + K R N E SLL K ++G
Sbjct: 23084 FTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVG 23143
Query: 386 TYVVHISST 394
YVV ++++
Sbjct: 23144 HYVVKLTNS 23152
Score = 36.7 bits (81), Expect = 0.27
Identities = 37/188 (19%), Positives = 77/188 (40%), Gaps = 13/188 (6%)
Query: 33 LELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFI--TENG--NLIIRQLS 88
++ +T G +G + + + P P W K+ + I + + E+ L+IR ++
Sbjct: 2084 IQSQTVG-QGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVT 2142
Query: 89 RDDEGVYTCVAKNQYGTDESRGRLIVLRAP--RFLEKLPPRITAQVNSVVFLHCNADVDP 146
+D A N G S L+V F ++L + + +++ C +P
Sbjct: 2143 AEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETS-EP 2201
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
+ W +G+ + + ++ K+ L+I + SD DY CV+ + +
Sbjct: 2202 FVKVK--WYKDGMEVHEGDKYRMHSDRKVHF--LSILTIDTSDAEDYSCVLVED-ENVKT 2256
Query: 207 HVQLRIEG 214
+L +EG
Sbjct: 2257 TAKLIVEG 2264
Score = 36.7 bits (81), Expect = 0.27
Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 8/113 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETY--GSE---GGNVTLKCKPEAAP 55
+Y+ A+N+ S S L L+ +F + ++L + G E +T+ P
Sbjct: 14290 LYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 14349
Query: 56 KPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
+PT TW + V+ G + + ++ L+I R D+G+YT +N+ T
Sbjct: 14350 RPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKT 14402
Score = 36.3 bits (80), Expect = 0.35
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 15/115 (13%)
Query: 5 EAKNQLKASYSSAQLRVLSLKPSF--KKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWK 62
+ K Q+K S+AQL+VL P F K H + E +TLKC E + W
Sbjct: 12569 QIKAQVKELSSTAQLKVLEADPYFTVKLH----DKTAVEKDEITLKC--EVSKDVPVKWF 12622
Query: 63 KDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
KD I K I +G L I++ D+G Y C GTD+++ + V
Sbjct: 12623 KDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTV 12673
Score = 35.9 bits (79), Expect = 0.47
Identities = 38/140 (27%), Positives = 62/140 (44%), Gaps = 14/140 (10%)
Query: 61 WKKDNIVIGAGGKRFITENG---NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W K+ +V+ + K I+ G +L I+ + DE VY + G + RL V
Sbjct: 2740 WIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGF----RLGRLGASARLHV-ET 2794
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+ ++K P +TA N+ V + D + W H + IK S + K+
Sbjct: 2795 VKIIKK-PKDVTALENATVAFEVSVSHDTV---PVKWFHKNVEIKPSDKHRLVSERKVH- 2849
Query: 178 GELTIYNVSLSDVGDYECVV 197
+L + N+S SD G+Y VV
Sbjct: 2850 -KLMLQNISPSDAGEYTAVV 2868
Score = 35.9 bits (79), Expect = 0.47
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 15/103 (14%)
Query: 215 PPGPPGGVQILGIQRSSVTLEW-TDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
PPGPP +++ + S+TL W G PI GY++ R I++ P+
Sbjct: 19423 PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPK-------IADASPD-EG 19474
Query: 274 VDRYNG-----RKRATVSTTLLPWAIYEFRIQAINILGPGQPS 311
R N RK TV T+L YEFR+ A N +G G+P+
Sbjct: 19475 WKRCNAAAQLVRKEFTV-TSLDENQEYEFRVCAQNQVGIGRPA 19516
Score = 35.9 bits (79), Expect = 0.47
Identities = 94/434 (21%), Positives = 168/434 (38%), Gaps = 61/434 (14%)
Query: 218 PPGGVQILGIQRSSVTLEWTD-SNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDR 276
PP V+I I ++SV+L W + G ITGY++ R + W + NV E
Sbjct: 27697 PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRW--TKASFTNVTETQ- 27753
Query: 277 YNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPAN-VSGGG 335
+ + L + YEFR+ A N +G S S P + G
Sbjct: 27754 -------FIISGLTQNSQYEFRVFARNAVG-----------SISNPSEVVGPITCIDSYG 27795
Query: 336 GKTGDLTITWTPL-----PTSLQNGPGIHYK----IFWRRNGSEVEFQSLL-LKKYGNIG 385
G DL + +T + TS++ GI K I W ++ E++ +L+ ++ ++
Sbjct: 27796 GPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLA 27855
Query: 386 TYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTAL 445
+ ++ + Y++K++ N +G + V I D P + ++ + +
Sbjct: 27856 SILIKDADRLNSGCYELKLR--NAMGSASATIRVQIL---DKPGPPGGPIEFKTVTAEKI 27910
Query: 446 NVTWN-PIDQSRERLRGKLIGHR---LKYWKQENKE-EECIYYLSRTTRNWALIVGLQPD 500
+ W P D ++ ++ R W ++ EECI TT+ +I G +
Sbjct: 27911 TLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECII---TTTK---IIKGNE-- 27962
Query: 501 TYYYVKVMAFNSAGEGP--ESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQP- 557
Y +V A N G G ES+ + + P PP V ++ VVW +P
Sbjct: 27963 --YIFRVRAVNKYGIGEPLESDSVVAKNAFVTP-GPPGIPEVTKITKNSMTVVWS--RPI 28017
Query: 558 TNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSNGGD 617
+ + GY L + D+ + ++ + Y RV A + G
Sbjct: 28018 ADGGSDISGY--FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQ 28075
Query: 618 GRMSSPTIAFQIGD 631
G S P+ ++ D
Sbjct: 28076 GPFSEPSEFYKAAD 28089
Score = 35.5 bits (78), Expect = 0.62
Identities = 50/211 (23%), Positives = 75/211 (35%), Gaps = 21/211 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+AK+ +S L V+ F + +L+ E + E A W
Sbjct: 13281 YTCDAKD----FKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSRENAK---VKW 13333
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I G K I G L+I + DDE Y+C + T + G L VL
Sbjct: 13334 FKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVR----TARTSGMLTVLEEE 13389
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
K I + L C P + + + ++ R +I
Sbjct: 13390 AVFTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRI--- 13445
Query: 179 ELTIYNVSLSDVGDYECVVKSA--IGRISSH 207
L I N L D G+Y C + S+ G++ H
Sbjct: 13446 -LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH 13475
Score = 35.1 bits (77), Expect = 0.82
Identities = 56/235 (23%), Positives = 90/235 (38%), Gaps = 23/235 (9%)
Query: 1 MYQCEAKNQLKASYSSAQLRV-----------LSLKPSFKKHPLELETYGSEGGNVTLKC 49
+Y CEAKN + +SA L V + + P PL+ +T SEG +C
Sbjct: 3308 VYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQ-DTVTSEGQPARFQC 3366
Query: 50 KPEAAPKPTFTWKKDNIVIGAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDE 107
+ + KD + + R + L I + +DEG YT VA N G
Sbjct: 3367 RVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVS 3426
Query: 108 SRGRLIVLRAPRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWN--HNGLRIKD 163
S L L AP + E++ I ++ +A+ + + + + L +
Sbjct: 3427 STANL-SLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLS 3485
Query: 164 SSDLYVNK--RIKIDGGELTIYNVSLSDV--GDYECVVKSAIGRISSHVQLRIEG 214
S +Y K K G + I VS +D+ GD + + IG +Q G
Sbjct: 3486 ESPVYSTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNG 3540
Score = 34.7 bits (76), Expect = 1.1
Identities = 62/251 (24%), Positives = 102/251 (40%), Gaps = 23/251 (9%)
Query: 9 QLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDNIVI 68
+++ +SA+L V ++ F PLE +T EG T C+ + K W K++ +
Sbjct: 12484 EVEGKKTSARLFVTGIRLKFMS-PLEDQTV-KEGETATFVCEL-SHEKMHVVWFKNDAKL 12540
Query: 69 GAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA-PRFLEKL 124
I+ G L +++++ DD K Q S +L VL A P F KL
Sbjct: 12541 HTSRTVLISSEGKTHKLEMKEVTLDD----ISQIKAQVKELSSTAQLKVLEADPYFTVKL 12596
Query: 125 PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE--LTI 182
+ TA + L C D W +G I S IK DG L I
Sbjct: 12597 HDK-TAVEKDEITLKCEVSKD----VPVKWFKDGEEIVPSPKY----SIKADGLRRILKI 12647
Query: 183 YNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSNSN 242
L D G+Y C + + + V+ R+ P GV++ + + +E ++ + +
Sbjct: 12648 KKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVH 12707
Query: 243 GR-PITGYMLT 252
G+ + G LT
Sbjct: 12708 GQWKLKGQPLT 12718
Score = 34.7 bits (76), Expect = 1.1
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFITENGNLI--IRQLSRDDEGVYTCV 98
G N+ ++ PKPT TWKK D I+ F T + I I + R D G Y
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 22066
Query: 99 AKNQYG 104
A+N G
Sbjct: 22067 ARNIVG 22072
Score = 33.9 bits (74), Expect = 1.9
Identities = 23/102 (22%), Positives = 41/102 (40%), Gaps = 11/102 (10%)
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNG-RPITGYMLTGRTHWNSTWYVISENIPNVM 272
G P P ++ + + + + W +S+G PI GY++ + + W ++ +
Sbjct: 20017 GVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRST 20076
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
E L+ Y FRI A+N G PS P+
Sbjct: 20077 EYP----------CAGLVEGLEYSFRIYALNKAGSSPPSKPT 20108
Score = 32.7 bits (71), Expect = 4.3
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
Query: 216 PGPPGGVQILGIQRSSVTLEWT-DSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEV 274
P P ++ + + S+ + W ++ G I GY+L R W +
Sbjct: 23664 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHK-------- 23715
Query: 275 DRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPS 314
R G R V T L+ YEFR+ A N G +PS PS
Sbjct: 23716 -RLIGELRLRV-TGLIENHDYEFRVSAENAAGLSEPSPPS 23753
Score = 32.3 bits (70), Expect = 5.7
Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 1/78 (1%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITEN-GNLIIRQLSRDDEGVYTCVAK 100
G ++ L + P PT W K + + T++ L + +R+D G YT +
Sbjct: 29299 GASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVE 29358
Query: 101 NQYGTDESRGRLIVLRAP 118
N G+ + VL P
Sbjct: 29359 NNSGSKSITFTVKVLDTP 29376
Score = 31.9 bits (69), Expect = 7.6
Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 14/141 (9%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDN--IVIGAGGKRFITENG-- 80
KP F P+ + EG K P P W D IV K I E+G
Sbjct: 1456 KPVFVLKPVSFKCL--EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1513
Query: 81 NLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA------PRFLEKLPPRITAQVNS 134
+LII + D G +T VA+N+ G S ++ + A P F+EKL + + S
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGR-SSISVILTVEAVEHQVKPMFVEKL-KNVNIKEGS 1571
Query: 135 VVFLHCNADVDPILDTAYLWN 155
+ + A +P D +L N
Sbjct: 1572 QLEMKVRATGNPNPDIVWLKN 1592
Score = 31.9 bits (69), Expect = 7.6
Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 18/156 (11%)
Query: 61 WKKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W K +I + K I +G L+I DDEGVYT + + ++ RL V
Sbjct: 12444 WSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK----KTSARLFVTGI 12499
Query: 118 P-RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
+F+ L + + + F+ C + + +W N ++ S + ++ K
Sbjct: 12500 RLKFMSPLEDQTVKEGETATFV-CELSHEKM---HVVWFKNDAKLHTSRTVLISSEGKTH 12555
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+L + V+L D+ +K+ + +SS QL++
Sbjct: 12556 --KLEMKEVTLDDISQ----IKAQVKELSSTAQLKV 12585
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/211 (28%), Positives = 93/211 (44%), Gaps = 10/211 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N ++ L V + P K P + E V L C+ P+PT TW
Sbjct: 822 YTCSARNSAGVAHKHVFLTVQA-SPVVKPLPSVVRAVAEE--EVLLPCEASGIPRPTITW 878
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+K+ + + G + G L I S +D G Y C+AKN G+ + RL+V + P +
Sbjct: 879 QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV-QVPPVI 937
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
E P ++ S FL C A P + W+ +G + + + + GEL
Sbjct: 938 ENGLPDLSTTEGSHAFLPCKARGSP--EPNITWDKDGQPVSGAEGKFTIQ----PSGELL 991
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ N+ D G Y C ++A+GR V L I
Sbjct: 992 VKNLEGQDAGTYTCTAENAVGRARRRVHLTI 1022
Score = 82.6 bits (195), Expect = 4e-15
Identities = 65/217 (29%), Positives = 99/217 (45%), Gaps = 15/217 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C AKN ++ +L V+ + P + +L T +EG + L CK +P+P TW
Sbjct: 912 YLCIAKNSAGSAMGKTRL-VVQVPPVIENGLPDLST--TEGSHAFLPCKARGSPEPNITW 968
Query: 62 KKDNI-VIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD V GA GK I +G L+++ L D G YTC A+N G R L +L P F
Sbjct: 969 DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF 1028
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE- 179
LP + ++ ++L C A P W N + + V+++ DGG
Sbjct: 1029 -TTLPGDRSLRLGDRLWLRCAARGSPTPRIG--WTVNDRPVTEG----VSEQ---DGGST 1078
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L VS D G Y C ++ +GR + + ++ P
Sbjct: 1079 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 1115
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 10/178 (5%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GG++ L C P P W KD + + R +NG+L I + RDD G Y C+A+N
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 1189
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G + L++ AP F + P +T + V L C A +P +L LR
Sbjct: 1190 EMGVAKKVVILVLQSAPVF-QVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLR- 1247
Query: 162 KDSSDLYVNKRIK-IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGP 218
++R++ + G L + NV D G Y+CV + +G ++ L + G P
Sbjct: 1248 -------ASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGMGHP 1298
Score = 74.9 bits (176), Expect = 8e-13
Identities = 59/218 (27%), Positives = 91/218 (41%), Gaps = 8/218 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C+ N + + L V + P+F+ E + + G + L C P PT T
Sbjct: 13 LYSCKVSNVAGEAVRTFTLTV-QVPPTFENPKTETVSQVA-GSPLVLTCDVSGVPAPTVT 70
Query: 61 WKKDNIVIGAGGKR-FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W KD + + + ++ G L + +L G YTCVA+N + VL APR
Sbjct: 71 WLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 130
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
R + V L C AD P D A+L + + L D+ + R +DGG
Sbjct: 131 IRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL----GQDMGPHLRFYLDGG 186
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L + + SD G Y CV + G + + + PP
Sbjct: 187 SLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPP 224
Score = 74.9 bits (176), Expect = 8e-13
Identities = 54/188 (28%), Positives = 77/188 (40%), Gaps = 9/188 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQY 103
V L C P PT +W K +GA G + ++ +G L I Q G YTC A+N
Sbjct: 771 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSA 830
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKD 163
G L V +P ++ LP + A V L C A P W GL +
Sbjct: 831 GVAHKHVFLTVQASP-VVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEGLNVAT 887
Query: 164 SSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ 223
V + GG+L I + S D G+Y C+ K++ G +L ++ PP G+
Sbjct: 888 GVSTQV-----LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 942
Query: 224 ILGIQRSS 231
L S
Sbjct: 943 DLSTTEGS 950
Score = 72.1 bits (169), Expect = 6e-12
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 9/213 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A++ A S ++RV + P+ G G + L+C EA P P T
Sbjct: 472 LYTCLAESPAGAIEKSFRVRVQA-PPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKIT 530
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D IV+ E G + ++ LS D G Y+C A+N G+ R+ + P
Sbjct: 531 WHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPT 590
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
+ PP + VN L C AD P W + + + S + + G
Sbjct: 591 -IRSGPPAVNVSVNQTALLPCQADGVPA--PLVSWRKDRVPLDPRSPRFE----ILPEGS 643
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L I V D G Y C+ ++ G LR+
Sbjct: 644 LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 676
Score = 68.1 bits (159), Expect = 9e-11
Identities = 56/208 (26%), Positives = 87/208 (41%), Gaps = 16/208 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + + VL + P + + E + EG V L C+ + P P W
Sbjct: 106 YTCVAENTQAEARKDFVVAVL-VAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAW 164
Query: 62 KKDNIVIGAG---GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD +G RF + G+L+++ L D G YTCVA N G D + VL P
Sbjct: 165 LKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPP 224
Query: 119 RFLEKL--PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
+ + ++ +V + C P + ++L KD L +++R +
Sbjct: 225 TIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWL--------KDGLPLPLSQRTLLH 276
Query: 177 GG--ELTIYNVSLSDVGDYECVVKSAIG 202
G L I V L+D G + CV S G
Sbjct: 277 GSGHTLRISKVQLADAGIFTCVAASPAG 304
Score = 67.3 bits (157), Expect = 2e-10
Identities = 54/216 (25%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + + L +L L P F P + G + L+C +P P W
Sbjct: 1003 YTCTAENAVGRARRRVHLTILVL-PVFTTLPGDRSL--RLGDRLWLRCAARGSPTPRIGW 1059
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQ-LSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
++ + G + G+ + R +SR+D G Y C A+N+ G ++ + V AP
Sbjct: 1060 TVNDRPVTEGVSE--QDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVL 1117
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + V + L C DP+ D W +GL ++ S + R ++ G L
Sbjct: 1118 QGEAFSYLVEPVGGSIQLDCVVRGDPVPDIH--WIKDGLPLRGS-----HLRHQLQNGSL 1170
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
TI+ D G Y+C+ ++ +G V L ++ P
Sbjct: 1171 TIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAP 1206
Score = 66.1 bits (154), Expect = 4e-10
Identities = 53/223 (23%), Positives = 92/223 (41%), Gaps = 13/223 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A ++ + QL V+ P + E + G + L C + P+P TW
Sbjct: 382 YSCVAVSEAGEARRHFQLTVME-PPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 440
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD + + L + + D G+YTC+A++ G E R+ V P +
Sbjct: 441 HKDGQAL-TRLENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIV 499
Query: 122 EKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
PR + + L C+ + +P W+ +G+ +++ + +R G L
Sbjct: 500 GPRGPRFVVGLAPGQLVLECSVEAEPA--PKITWHRDGIVLQEDAHTQFPER----GRFL 553
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP----GPP 219
+ +S +D GDY C ++A G S ++ I P GPP
Sbjct: 554 QLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPP 596
Score = 52.8 bits (121), Expect = 4e-06
Identities = 35/116 (30%), Positives = 52/116 (44%), Gaps = 6/116 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRV-LSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C A+N A +S RV + P+ + P + S L C+ + P P +
Sbjct: 566 YSCTARNA--AGSTSVAFRVEIHTVPTIRSGPPAVNV--SVNQTALLPCQADGVPAPLVS 621
Query: 61 WKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W+KD + + RF I G+L I+ + D G Y C+A N G+D L VL
Sbjct: 622 WRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 677
Score = 52.0 bits (119), Expect = 7e-06
Identities = 40/164 (24%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 76 ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEK-LPPRITAQVNS 134
+ + +L + + D G Y+CVA ++ G +L V+ P + P ++ +
Sbjct: 363 LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGA 422
Query: 135 VVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYE 194
+ L C+A P W+ +G + + L N R L + NV + D G Y
Sbjct: 423 PMELLCDAQGTP--QPNITWHKDGQAL---TRLENNSRAT---RVLRVENVQVRDAGLYT 474
Query: 195 CVVKSAIGRISSHVQLRIEGPP---GPPGGVQILGIQRSSVTLE 235
C+ +S G I ++R++ PP GP G ++G+ + LE
Sbjct: 475 CLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLE 518
Score = 41.9 bits (94), Expect = 0.007
Identities = 39/174 (22%), Positives = 66/174 (37%), Gaps = 12/174 (6%)
Query: 47 LKCKPEAAPKPTFTWKKD----NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
L C+ +PKP W KD + + G R + N L++ D + CV N+
Sbjct: 680 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA-LLLTAPGPQDSAQFECVVSNE 738
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + R + + P + T + + V L C++ P + W+ G ++
Sbjct: 739 VG-EAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVS--WSKAGAQLG 795
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
Y R+ G L I G Y C +++ G HV L ++ P
Sbjct: 796 ARGSGY---RVS-PSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASP 845
Score = 33.5 bits (73), Expect = 2.5
Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 6/118 (5%)
Query: 82 LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCN 141
L I++ D+G+Y+C N G L V P F ++ S + L C
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC- 59
Query: 142 ADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKS 199
DV + W + + ++ S+ V R GG L + + + G Y CV ++
Sbjct: 60 -DVSGVPAPTVTWLKDRMPVESSAVHGVVSR----GGRLQLSRLQPAQAGTYTCVAEN 112
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 95.1 bits (226), Expect = 7e-19
Identities = 60/211 (28%), Positives = 93/211 (44%), Gaps = 10/211 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N ++ L V + P K P + E V L C+ P+PT TW
Sbjct: 56 YTCSARNSAGVAHKHVFLTVQA-SPVVKPLPSVVRAVAEE--EVLLPCEASGIPRPTITW 112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+K+ + + G + G L I S +D G Y C+AKN G+ + RL+V + P +
Sbjct: 113 QKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV-QVPPVI 171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
E P ++ S FL C A P + W+ +G + + + + GEL
Sbjct: 172 ENGLPDLSTTEGSHAFLPCKARGSP--EPNITWDKDGQPVSGAEGKFTIQ----PSGELL 225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+ N+ D G Y C ++A+GR V L I
Sbjct: 226 VKNLEGQDAGTYTCTAENAVGRARRRVHLTI 256
Score = 77.4 bits (182), Expect = 2e-13
Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C AKN ++ +L V+ + P + +L T +EG + L CK +P+P TW
Sbjct: 146 YLCIAKNSAGSAMGKTRL-VVQVPPVIENGLPDLST--TEGSHAFLPCKARGSPEPNITW 202
Query: 62 KKDNI-VIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD V GA GK I +G L+++ L D G YTC A+N G R L +L P F
Sbjct: 203 DKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVF 262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDP 146
LP + ++ ++L C A P
Sbjct: 263 -TTLPGDRSLRLGDRLWLRCAARGSP 287
Score = 74.9 bits (176), Expect = 8e-13
Identities = 54/188 (28%), Positives = 77/188 (40%), Gaps = 9/188 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQY 103
V L C P PT +W K +GA G + ++ +G L I Q G YTC A+N
Sbjct: 5 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSA 64
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKD 163
G L V +P ++ LP + A V L C A P W GL +
Sbjct: 65 GVAHKHVFLTVQASP-VVKPLPSVVRAVAEEEVLLPCEASGIP--RPTITWQKEGLNVAT 121
Query: 164 SSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ 223
V + GG+L I + S D G+Y C+ K++ G +L ++ PP G+
Sbjct: 122 GVSTQV-----LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLP 176
Query: 224 ILGIQRSS 231
L S
Sbjct: 177 DLSTTEGS 184
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 94.7 bits (225), Expect = 1e-18
Identities = 77/321 (23%), Positives = 130/321 (40%), Gaps = 26/321 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ A +QL ++ + P F P + + G G V L C E P PT W
Sbjct: 497 YTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQD--GIYGKAVILNCSAEGYPVPTIVW 553
Query: 62 KKDNIV-------IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
K I G+ + NG+L+I+ + +D G Y C N G D S+ +
Sbjct: 554 KFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLT 613
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKRI 173
++ P + P A + C A + PI+ W I Y+
Sbjct: 614 VKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPII---VRWEKEDRIINPEMARYLVSTK 670
Query: 174 KIDG---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
++ L I D G + C ++ G +QL ++ PP PP ++I ++
Sbjct: 671 EVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-EIEIKDVKAR 729
Query: 231 SVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTLL 290
++TL WT PITGY + + + +W ++ +V + + + +
Sbjct: 730 TITLRWTMGFDGNSPITGYDIECKNK-SDSW----DSAQRTKDV---SPQLNSATIIDIH 781
Query: 291 PWAIYEFRIQAINILGPGQPS 311
P + Y R+ A N +G +PS
Sbjct: 782 PSSTYSIRMYAKNRIGKSEPS 802
Score = 71.7 bits (168), Expect = 8e-12
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G V L CK P+P + W KDN+ + G+ T G L+I + D G Y C N
Sbjct: 69 GQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSN 127
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+YGT + GRL V + P P ++ + V S V L C+ V D W NG +
Sbjct: 128 RYGTAKVIGRLYV-KQPLKATISPRKVKSSVGSQVSLSCS--VTGTEDQELSWYRNGEIL 184
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE-GPP 216
++ + I+ L + ++ SD G Y+C V+ +VQ+ +E G P
Sbjct: 185 NPGKNVRIT---GINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 237
Score = 64.5 bits (150), Expect = 1e-09
Identities = 63/220 (28%), Positives = 100/220 (45%), Gaps = 11/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP-TFT 60
Y C Q + S +S + V P F + P E + S G V + C + P T T
Sbjct: 403 YTCNVLVQPQLS-TSQSVHVTVKVPPFIQ-PFEFPRF-SIGQRVFIPCVVVSGDLPITIT 459
Query: 61 WKKDNIVI-GAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
W+KD I G+ G I +L I LS G YTC+A+N+ E + +LIV
Sbjct: 460 WQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 519
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-D 176
P+F+ + P V L+C+A+ P+ + ++ G + + +N RI++
Sbjct: 520 PKFVVQ-PRDQDGIYGKAVILNCSAEGYPVPTIVWKFS-KGAGVPQFQPIALNGRIQVLS 577
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGR-ISSHVQLRIEGP 215
G L I +V D G Y C V + +G +S + L ++ P
Sbjct: 578 NGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 617
Score = 53.6 bits (123), Expect = 2e-06
Identities = 53/220 (24%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A++ V P+ + P++ T G + + C+ P +
Sbjct: 311 VYRCTANNSAGVVLYQARINVRG--PASIR-PMKNIT-AIAGRDTYIHCRVIGYPYYSIK 366
Query: 61 WKKDNIVIGAGGKRFITEN-GNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W K++ ++ ++ EN G L + + ++ DEG YTC Q S+ + ++ P
Sbjct: 367 WYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 426
Query: 119 RFLEKLP-PRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID- 176
F++ PR + + VF+ C V L W +G I S + ++ ID
Sbjct: 427 PFIQPFEFPRFS--IGQRVFIPCVV-VSGDLPITITWQKDGRPIPGSLGVTIDN---IDF 480
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I N+SL G+Y C+ ++ + QL + PP
Sbjct: 481 TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPP 520
Score = 52.4 bits (120), Expect = 5e-06
Identities = 51/182 (28%), Positives = 72/182 (39%), Gaps = 18/182 (9%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGG----KRFITENGNLI----IRQLSRDDEGVYT 96
V+L C + P PT TW D+ I GG + IT GN++ I D GVY
Sbjct: 254 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 313
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
C A N G + R+ V R P + + ITA ++HC P + N
Sbjct: 314 CTANNSAGVVLYQARINV-RGPASIRPM-KNITAIAGRDTYIHCRVIGYPYYSIKWYKNS 371
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLS-DVGDYEC-VVKSAIGRISSHVQLRIEG 214
N L + N G L + +V D G+Y C V+ S V + ++
Sbjct: 372 NLLPFNHRQVAFEN------NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKV 425
Query: 215 PP 216
PP
Sbjct: 426 PP 427
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 93.9 bits (223), Expect = 2e-18
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 80 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 135
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 136 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 194
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 195 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 248
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
LTI+ V+ D G Y CV + + + + L + G
Sbjct: 249 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLG 286
Score = 46.0 bits (104), Expect = 4e-04
Identities = 42/177 (23%), Positives = 67/177 (37%), Gaps = 9/177 (5%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITE--NGNLIIRQLSRDDEGVYTCVA 99
G + L C+ PKPT W + + + E +I R VY C
Sbjct: 26 GEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNT 85
Query: 100 KNQYGTDESRGRLIVLRA-PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
N++G + + VL PR L I + + L C PI + N G
Sbjct: 86 SNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG 145
Query: 159 LRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
+ D + +V + G L I + D G Y CV + +G+ + V+L ++ P
Sbjct: 146 SNL-DGGNYHV-----YENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDP 196
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 93.9 bits (223), Expect = 2e-18
Identities = 64/218 (29%), Positives = 102/218 (46%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKP---SFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC N+ ++A + VL + P S + + + Y L C +P P
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN----RTRLDCPFFGSPIP 460
Query: 58 TFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T W K+ GG + ENG+L I+ + ++D+G+YTCVA N G E++ RL V +
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV-K 519
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
P + ++P A+ + V L C DP L W +KD LY+ R+K +
Sbjct: 520 DPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW------LKDDEPLYIGNRMKKE 573
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
LTI+ V+ D G Y CV + + + + L + G
Sbjct: 574 DDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLG 611
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 25/231 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCK-PEAAPKPTFT 60
YQC A+N+ + S+ +S P + K L+ EG +TL+C P P P
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLD-PVVVQEGAPLTLQCNPPPGLPSPVIF 174
Query: 61 WKKDNIVIGAGGKRFIT-ENGNLIIRQ-LSRDDEGVYTCVAKNQY-GTDESRG--RLIVL 115
W ++ KR NG+L + +D + Y+C A+ + T + + L VL
Sbjct: 175 WMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVL 234
Query: 116 RAPRFLEKLP----PRITAQVNSV-----VFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
E+ P P+ TA V + L C A P D A+ K D
Sbjct: 235 TTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAW--------YKKGGD 286
Query: 167 LYVNK-RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L +K + + L I NVS D G+Y C+ + +G I + +R++ P
Sbjct: 287 LPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
Score = 46.4 bits (105), Expect = 3e-04
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 7/176 (3%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
G ++ L+C P P W K + + +F N L I +S +D G Y C+A N
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASN 320
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G+ + V AP +L++ P + L C A+ +P W NG +
Sbjct: 321 KMGSIRHTISVRVKAAPYWLDE-PKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPL 377
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI-EGPP 216
+ + N ++ G + + +S Y+C + G + ++ + + + PP
Sbjct: 378 QSAPP---NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPP 430
Score = 45.2 bits (102), Expect = 8e-04
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFIT---ENGNLII--RQLSRDD--EGVYT 96
N+ ++C+ + P P+F W +++ ++ +G L+I R R + EG Y
Sbjct: 58 NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQ 117
Query: 97 CVAKNQYGTD-ESRGRLIVLRAPRF-LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C A+N++GT +R RL V ++P + E L P + Q + + L CN + W
Sbjct: 118 CFARNKFGTALSNRIRLQVSKSPLWPKENLDP-VVVQEGAPLTLQCNPP-PGLPSPVIFW 175
Query: 155 NHNGLRIKDSSDLYVNKRI-KIDGGELTIYNVSLSDV-GDYEC 195
+ + + +KR+ + G+L NV L D+ DY C
Sbjct: 176 MSSSM-----EPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSC 213
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 93.1 bits (221), Expect = 3e-18
Identities = 65/216 (30%), Positives = 102/216 (47%), Gaps = 14/216 (6%)
Query: 1 MYQCEAKNQL-KASYSSAQLRVLSL--KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC A+N +A SA LR SL KPSF P + E G + TL+C P P
Sbjct: 302 VYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVL--IGTSTTLECMATGHPHP 359
Query: 58 TFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
TW +DN + G R + + L ++ +++ D G +TC A N +GT ++ +IV
Sbjct: 360 LITWTRDN-GLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAP 418
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P+F ++ + ++V +L C AD +P +W G ++ V +
Sbjct: 419 PQFTVTPKDQVVLEEHAVEWL-CEADGNP--PPVIVWTKTGGQLPVEGQHTV-----LSS 470
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
G L I + D G YEC S++G VQL ++
Sbjct: 471 GTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVK 506
Score = 79.8 bits (188), Expect = 3e-14
Identities = 55/221 (24%), Positives = 96/221 (43%), Gaps = 11/221 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
+ C A N ++A + ++ P F P + E V C+ + P P W
Sbjct: 396 FTCHANNSHGTVQAAANI-IVQAPPQFTVTPKDQVVL--EEHAVEWLCEADGNPPPVIVW 452
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K + G+ + +G L I + ++ D+G Y C A + G + +L V +A
Sbjct: 453 TKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAV 512
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+LP + +V + + C+A +P WN G++I +S +V+ D G L
Sbjct: 513 FTQLPQDTSVEVGKNINISCHAQGEP--QPIITWNKEGVQITESGKFHVD-----DEGTL 565
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
TIY+ D G YECV +++ G +++ L + G G
Sbjct: 566 TIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAG 606
Score = 56.0 bits (129), Expect = 4e-07
Identities = 45/198 (22%), Positives = 83/198 (41%), Gaps = 19/198 (9%)
Query: 26 PSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDN--IVIGAGGKRFITENGNLI 83
P P ++E G V C+ E PKP W +N + + + + ++G L+
Sbjct: 234 PRITFEPQDVEV--PSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLM 291
Query: 84 IRQLSRDDEGVYTCVAKNQYGTDESRGRLI----VLRAPRFLEKLPPRITAQVNSVVFLH 139
IR D+GVY C+A+N G +++ ++ + P F+ + P + + L
Sbjct: 292 IRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQ-PQDTEVLIGTSTTLE 350
Query: 140 CNADVDPILDTAYLWNH-NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVK 198
C A P W NGL + S + + G L + N++ D G + C
Sbjct: 351 CMATGHP--HPLITWTRDNGLELDGS------RHVATSSG-LYLQNITQRDHGRFTCHAN 401
Query: 199 SAIGRISSHVQLRIEGPP 216
++ G + + + ++ PP
Sbjct: 402 NSHGTVQAAANIIVQAPP 419
>AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 1029
Score = 93.1 bits (221), Expect = 3e-18
Identities = 63/212 (29%), Positives = 102/212 (48%), Gaps = 3/212 (1%)
Query: 341 LTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPY 400
+ +TW LQNG Y+I +R + FQ ++ + + V + + +T Y
Sbjct: 18 IRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQY 77
Query: 401 DVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLR 460
+ VQA N G GP S+ + + ED+P P+ V A + + +++++W+ + S+E L
Sbjct: 78 GLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTL--SKEALN 135
Query: 461 GKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESE 520
G L G R+ YW E TT+ + GL+ T Y ++V+AF AG+G SE
Sbjct: 136 GILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSE 195
Query: 521 RYLERTFRKAPQKPPASVNVWAHDPTTLRVVW 552
+ RT P PPA V A + + V W
Sbjct: 196 QIFTRTKEDVP-GPPAGVKAAAASASMVFVSW 226
Score = 64.1 bits (149), Expect = 2e-09
Identities = 50/195 (25%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 428 PQVAPQLVSARSFNSTALNVTWNPIDQSRER--LRGKLIGHRLKYWKQENKEEECIYYLS 485
P PQ V +S ++ VTW + + +RG IG+R +Y N + I +
Sbjct: 1 PDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYR-EYSTGGNFQFNIISVDT 59
Query: 486 RTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDP 545
+ L T Y + V A N AG GP S+ + T P PP +V A P
Sbjct: 60 SGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSP 119
Query: 546 TTLRVVWRYVQPTNEEEPLLGYKVRLWE--LDQDMSTANDTIVPIEHKLEAYISNIIPGK 603
++ + W + L G++V W +D ++ + I + LE + +
Sbjct: 120 ESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKN-ITTTQPSLE--LDGLEKYT 176
Query: 604 SYNLRVLAYSNGGDG 618
+Y+++VLA++ GDG
Sbjct: 177 NYSIQVLAFTRAGDG 191
Score = 60.1 bits (139), Expect = 3e-08
Identities = 80/323 (24%), Positives = 128/323 (39%), Gaps = 23/323 (7%)
Query: 215 PPGPPGGVQILGIQRSSVTLEWTDSNSNGRP--ITGYMLTGRTHWNSTWYVISENIPNVM 272
P GPP V + I S+ + W + + I GY + R + + N++
Sbjct: 1 PDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQF-----NII 55
Query: 273 EVDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVS 332
VD +G L + Y +QA N G G PS+ +T D P P NV
Sbjct: 56 SVDT-SGDSEVYTLDNLNKFTQYGLVVQACNRAGTG-PSSQEIITTTLEDVPSYPPENVQ 113
Query: 333 GGGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTY--VVH 390
++I+W+ L NG +++ + N + E L + NI T +
Sbjct: 114 AIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGE-----LGEIKNITTTQPSLE 168
Query: 391 ISSTYFYTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWN 450
+ YT Y ++V AF G G SE + + ED+P P V A + +++ + V+W
Sbjct: 169 LDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG-PPAGVKAAAASASMVFVSWL 227
Query: 451 PIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAF 510
P +L G +I + + S + ++ I L + Y V V+A
Sbjct: 228 P----PLKLNG-IIRKYTVFCSHPYPTVISEFEASPDSFSYR-IPNLSRNRQYSVWVVAV 281
Query: 511 NSAGEGPESERYLERTFRKAPQK 533
SAG G SE KAP +
Sbjct: 282 TSAGRGNSSEIITVEPLAKAPAR 304
Score = 59.7 bits (138), Expect = 3e-08
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 20/229 (8%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDN----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVA 99
++ L CK P P W KD+ ++ G+R I NG+ IIR + +D G Y+C+A
Sbjct: 319 DIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 378
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQ---VNSVVFLHCNADVDPILDTAYLWNH 156
N +G+DE I+L + PR+T +S+ D Y+ +
Sbjct: 379 NNNWGSDE-----IILNLQVQVPPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY 433
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAI--GRISSHVQLRIEG 214
+ +D+S+ + + I + N+ + ++ + GRIS ++ + G
Sbjct: 434 S----EDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLG 489
Query: 215 PPGPPGGVQIL--GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
Q L I + V L N G PIT + L R + W
Sbjct: 490 KEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVW 538
Score = 38.3 bits (85), Expect = 0.087
Identities = 28/117 (23%), Positives = 57/117 (48%), Gaps = 7/117 (5%)
Query: 416 SEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQEN 475
S+ + + +P P+L +++ S+++ ++W P D +RG ++ + ++N
Sbjct: 384 SDEIILNLQVQVPPDQPRLTVSKT-TSSSITLSWLPGDNGGSSIRGYIL-----QYSEDN 437
Query: 476 KEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQ 532
E+ + +S + R++ L L+ T+Y + A N G G SE +T K PQ
Sbjct: 438 SEQWGSFPISPSERSYRL-ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQ 493
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 92.7 bits (220), Expect = 4e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4238 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4294
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4295 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPV 4351
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4352 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4403
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4404 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4441
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3691 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3747
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3748 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3806
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3807 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3862
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3863 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3898
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3966 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4022
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4023 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4082
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4083 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4134
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4135 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4170
Score = 82.6 bits (195), Expect = 4e-15
Identities = 68/222 (30%), Positives = 98/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A N S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3034 YTCIAINXAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3092
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3093 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3152
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L N+ RI++S L V RI G
Sbjct: 3153 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNYK--RIENSDSLEV--RILSGGS 3208
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3209 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3250
Score = 81.0 bits (191), Expect = 1e-14
Identities = 62/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2267 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2323
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2324 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2383
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ T W +G + S+ + RI
Sbjct: 2384 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTT--WFKDGWPVSLSNSV----RIL 2437
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2438 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2479
Score = 80.6 bits (190), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4147 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4203
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4204 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4263
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4264 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4314
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4315 VIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPP 4350
Score = 79.4 bits (187), Expect = 4e-14
Identities = 52/181 (28%), Positives = 82/181 (45%), Gaps = 12/181 (6%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2796 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2855
Query: 104 GTDESRGRLIVLRAPRFLE----KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
G D + + VL P +E LP +T VN + C + P + W +G
Sbjct: 2856 GEDSLQYDVRVL-VPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQ 2912
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPP 219
+ + + + +G L I N ++D+G Y CV ++ G + L + PP
Sbjct: 2913 PLLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVI 2968
Query: 220 G 220
G
Sbjct: 2969 G 2969
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 78.6 bits (185), Expect = 7e-14
Identities = 63/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 EGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4057 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4113
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4114 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4172
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4173 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4226
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4227 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4261
Score = 77.4 bits (182), Expect = 2e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3782 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3838
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3839 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3898
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3899 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3951
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3952 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3989
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4365 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4424
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4425 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4481
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4482 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4528
Score = 70.9 bits (166), Expect = 1e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3505 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3563
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3564 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3623
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3624 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3677
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3678 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3732
Score = 68.9 bits (161), Expect = 5e-11
Identities = 58/223 (26%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+CK P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L CNA +P W +G+ +K + N RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECNAAGNP--SPILTWLKDGVPVKAND----NFRIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 65/258 (25%), Positives = 95/258 (36%), Gaps = 27/258 (10%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTC 97
EG ++L C+ P P WKK + G R ++ L I + D +Y+C
Sbjct: 2211 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2270
Query: 98 VAKNQYGTDESRGRLIVLRAPRFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWN 155
VA N GT + L V P P I + L C +V I W
Sbjct: 2271 VASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW- 2327
Query: 156 HNGLRIKDSSDLYVNKRIKI--DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
+KD L K ++I +G L + N+ +SD G Y CV + G L +
Sbjct: 2328 -----MKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVH 2382
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNV 271
PP I+G RS + + NS +G L T + W V N +
Sbjct: 2383 APP------SIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRI 2436
Query: 272 MEVDRYNGRKRATVSTTL 289
+ GR + TT+
Sbjct: 2437 LS----GGRMLRLMQTTM 2450
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 LEKL-------PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
L P I+ V L C +V + W I S +
Sbjct: 1075 FGDLRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 64.9 bits (151), Expect = 9e-10
Identities = 65/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P + +L E + ++C +P P
Sbjct: 2847 YTCVAVNEAGEDSLQYDVRVL-VPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2905
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2906 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2965
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2966 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIK------LNTNTLIVPGGR 3019
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3020 TLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3079
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3080 LE-CESNAVPPPVITWYKNGRMITEST 3105
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3411 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3469
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3470 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3529
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3530 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3582
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3583 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3642
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3643 E-CKSDAVPPPVITWLRNG 3660
Score = 64.5 bits (150), Expect = 1e-09
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2401 EKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2460
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2461 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2518
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2519 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2568
Score = 64.5 bits (150), Expect = 1e-09
Identities = 58/220 (26%), Positives = 84/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3223 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3281
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3282 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3341
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C P W NGL + SS + R+
Sbjct: 3342 TIRGNKDEAEKLMTYVDTSINIECRXTGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3395
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3396 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3435
Score = 62.9 bits (146), Expect = 4e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNCLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 61.7 bits (143), Expect = 8e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3360 SINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3419
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3420 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3479
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3480 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3528
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2456 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2514
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2515 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2574
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2575 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2626
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2627 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2668
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2595 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2654
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2655 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2711
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2712 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2767
Score = 58.4 bits (135), Expect = 8e-08
Identities = 45/162 (27%), Positives = 63/162 (38%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K+ I R ++ L I + D G YTC+A N
Sbjct: 3170 VTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3229
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3230 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3287
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3288 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3327
Score = 58.0 bits (134), Expect = 1e-07
Identities = 68/262 (25%), Positives = 104/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPKEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECKTRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE ++ N PI ++ G
Sbjct: 1659 LTLE-CNAAGNPSPILTWLKDG 1679
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.2 bits (132), Expect = 2e-07
Identities = 50/221 (22%), Positives = 83/221 (37%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVIGAG--GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G + E L+I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVSNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 54.4 bits (125), Expect = 1e-06
Identities = 54/215 (25%), Positives = 84/215 (39%), Gaps = 12/215 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N LRV + P+ + S+ V L C+ +A P PT TW
Sbjct: 2081 YTCVAVNAAGEKQRDIDLRVY-VPPNIMGEEQNVSVLISQA--VELLCQSDAIPPPTLTW 2137
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I+EN +++ I D G YTC A N G E + + + P
Sbjct: 2138 LKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWVPPN 2197
Query: 121 L---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
+ ++L ++T +++ L C + P +W G + +D RI G
Sbjct: 2198 IGGSDEL-TQLTVIEGNLISLLCESSGIP--PPNLIWKKKGSPV--LTDSMGRVRILSGG 2252
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+L I SD Y CV + G L++
Sbjct: 2253 RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2287
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2693 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2752
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2753 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2810
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2811 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2865
Query: 212 IEGPP 216
+ PP
Sbjct: 2866 VLVPP 2870
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4418 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4474
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4475 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4527
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/170 (20%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + +L I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVSLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 4293
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 4294 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 4350
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 4351 FKGDYPSNWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 4402
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 4403 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 4440
Score = 87.4 bits (207), Expect = 1e-16
Identities = 70/222 (31%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+C+ A P P
Sbjct: 3033 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVI 3091
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 3092 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 3151
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 3152 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 3207
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 3249
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 3690 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 3746
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 3805
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 3861
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 3965 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 4021
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 4022 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 4081
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 4082 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 4133
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 4134 QIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 4169
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/221 (28%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
MY C A N + +L V + P ++ P L+ G V + C + P P T
Sbjct: 1147 MYLCVATNIAGNVTQAVKLNV-HVPPKIQRGPKHLKV--QVGQRVDIPCNAQGTPLPVIT 1203
Query: 61 WKKDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K + G+ ++ +G L I Q + D G+YTCVA N GTDE+ L V P
Sbjct: 1204 WSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPT 1263
Query: 120 FLEKLPPRITA----QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
+ PP T N + C A P W HNG ++ + I
Sbjct: 1264 VEDLEPPYNTTFQERVANQRIEFPCPAKGTP--KPTIKWLHNG---RELTGREPGISILE 1318
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
DG L I +V+ D G+Y CV + G L++ PP
Sbjct: 1319 DGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP 1359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 4146 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 4262
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 4263 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 4313
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 4314 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 79.4 bits (187), Expect = 4e-14
Identities = 61/222 (27%), Positives = 99/222 (44%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKK---HPLELETYGSEGGNVTLKCKPEAAPKP 57
+Y C A N + L+V ++P+ HP E+ + G +++L+C+ + P P
Sbjct: 2266 LYSCVASNVAGTAKKEYNLQVY-IRPTITNSGSHPTEIIV--TRGKSISLECEVQGIPPP 2322
Query: 58 TFTWKKD-NIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
T TW KD + +I A G + E L ++ + D G Y CVA N G + + L V
Sbjct: 2323 TVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHA 2382
Query: 117 APRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + + P I+ + V L C A P+ + W +G + S+ + RI
Sbjct: 2383 PPSIIGNHRSPENISVVEKNSVSLTCEASGIPL--PSITWFKDGWPVSLSNSV----RIL 2436
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L + ++ D G Y CVV++A G L + PP
Sbjct: 2437 SGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 79.0 bits (186), Expect = 5e-14
Identities = 51/180 (28%), Positives = 80/180 (44%), Gaps = 10/180 (5%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ AAP PT TW KD + + K I G ++ I + +D G YTCVA N+
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 104 GTDESRGRLIVLRAPRFL---EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G D + + VL P LP +T VN + C + P + W +G
Sbjct: 2855 GEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNS--WQKDGQP 2912
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+ + + + +G L I N ++D+G Y CV ++ G + L + PP G
Sbjct: 2913 LLEDD----HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIG 2968
Score = 78.6 bits (185), Expect = 7e-14
Identities = 54/215 (25%), Positives = 88/215 (40%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C ++ +S +S L V P P G G V++ C PKP W
Sbjct: 589 YHCMVSSEGGSSAASVFLTVQE-PPKVTVMPKNQSFTG--GSEVSIMCSATGYPKPKIAW 645
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
+++ I + +T +G L I+ + D G+Y C+A N GTD+ L + AP+ L
Sbjct: 646 TVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPK-L 704
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
+ + + + + C P W L ++ S+ L ++ + G L
Sbjct: 705 MVVQSELLVALGDITVMECKTSGIP--PPQVKWFKGDLELRPSTFLIIDPLL----GLLK 758
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I D GDY CV + GR + + L + PP
Sbjct: 759 IQETQDLDAGDYTCVAINEAGRATGKITLDVGSPP 793
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 4056 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 4112
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 4113 HKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 4171
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 4172 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 4225
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 4260
Score = 76.6 bits (180), Expect = 3e-13
Identities = 71/267 (26%), Positives = 99/267 (37%), Gaps = 8/267 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + QL V PS + L V L+CK P P TW
Sbjct: 1896 YTCVATNAAGETQQHIQLHVHE-PPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KDN ++ G +I I D G+Y CVA N G E L V AP
Sbjct: 1955 YKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS- 2013
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ + VN+ V L C A P + W +G + S+ ++ G L
Sbjct: 2014 ISGSNNMVAVVVNNPVRLECEARGIPA--PSLTWLKDGSPVSSFSN---GLQVLSGGRIL 2068
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTLEWTDSN 240
+ + +SD G Y CV +A G + LR+ PP G Q + + S S+
Sbjct: 2069 ALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSD 2128
Query: 241 SNGRPITGYMLTGRTHWNSTWYVISEN 267
+ P ++ G ISEN
Sbjct: 2129 AIPPPTLTWLKDGHPLLKKPGLSISEN 2155
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 3781 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 3837
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 3838 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 3897
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 3898 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 3950
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 3988
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 4424 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 4480
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 4481 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 70.5 bits (165), Expect = 2e-11
Identities = 48/177 (27%), Positives = 76/177 (42%), Gaps = 7/177 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGT 105
L C+ E P P W KDN+ + NG ++ + + + +D G Y+C A N GT
Sbjct: 1380 LFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGT 1439
Query: 106 DESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + VL P + P ++ +N V L C P D + + L + D
Sbjct: 1440 SQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDP 1499
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
N + G L + N +D G Y+C V +A G+ + ++L I PP GG
Sbjct: 1500 -----NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGG 1551
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 3504 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 3562
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 3563 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 3622
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 3623 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 3676
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 3677 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 3731
Score = 66.5 bits (155), Expect = 3e-10
Identities = 66/267 (24%), Positives = 106/267 (39%), Gaps = 16/267 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLEL--ETYGSEGGNVTLKCKPEAAPKPTF 59
Y C A N+ +RVL + P K +L E + ++C +P P
Sbjct: 2846 YTCVAVNEAGEDSLQYDVRVL-VPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRN 2904
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W+KD + NG ++ I D G Y CVA+N G+ + L V P
Sbjct: 2905 SWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPP 2964
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +T VN+ + L C P D ++L N ++ L N I G
Sbjct: 2965 SVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK------LNTNTLIVPGGR 3018
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVT 233
L I +SD G+Y C+ + G L + PP + ++ ++ +SV+
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078
Query: 234 LEWTDSNSNGRPITGYMLTGRTHWNST 260
LE +SN+ P+ + GR ST
Sbjct: 3079 LE-CESNAVPPPVITWYKNGRMITEST 3104
Score = 66.1 bits (154), Expect = 4e-10
Identities = 47/172 (27%), Positives = 70/172 (40%), Gaps = 8/172 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGA-GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGT 105
L C +P PT W KD +I G + + L+I Q + G+Y C+A N G
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD 1813
Query: 106 DESRGRLIVLRAPRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDS 164
+ + V P L R+ + V L C A+ P + + W + + +
Sbjct: 1814 HKKEFEVTVHVPPTIKSSGLSERVVVKYKPVA-LQCIANGIP--NPSITWLKDDQPVNTA 1870
Query: 165 SDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
N +I+ G L I L D G Y CV +A G H+QL + PP
Sbjct: 1871 QG---NLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 3222 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 3280
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 3281 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 3341 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 3394
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 3395 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 3434
Score = 65.3 bits (152), Expect = 7e-10
Identities = 71/297 (23%), Positives = 108/297 (36%), Gaps = 28/297 (9%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y CEA N + + + + + P+ + EG ++L C+ P P W
Sbjct: 2172 YTCEATNVAGKTEKNYNVNIW-VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Query: 62 KKDN---IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KK + G R ++ L I + D +Y+CVA N GT + L V P
Sbjct: 2231 KKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRP 2290
Query: 119 RFLE--KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
P I + L C +V I W +KD L K ++I
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLEC--EVQGIPPPTVTW------MKDGHPLIKAKGVEIL 2342
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
+G L + N+ +SD G Y CV + G L + PP I+G RS +
Sbjct: 2343 DEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPP------SIIGNHRSPENI 2396
Query: 235 EWTDSNSNGR--PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVSTTL 289
+ NS +G L T + W V N ++ GR + TT+
Sbjct: 2397 SVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS----GGRMLRLMQTTM 2449
Score = 65.3 bits (152), Expect = 7e-10
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 10/175 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVA 99
E +V+L C+ P P+ TW KD + I G ++ + Q + +D G YTCV
Sbjct: 2400 EKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 100 KNQYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNG 158
+N G + L VL P + E + + V L C +P+ + W+ +G
Sbjct: 2460 RNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEIT--WHKDG 2517
Query: 159 LRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
+++ ++ I GG L I NV + G Y C+ S G S L +
Sbjct: 2518 QPLQEDEAHHI-----ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 64.9 bits (151), Expect = 9e-10
Identities = 72/253 (28%), Positives = 109/253 (43%), Gaps = 21/253 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ + L V S P F + P ++ G NVTL C + P+PT W
Sbjct: 770 YTCVAINEAGRATGKITLDVGS-PPVFIQEPADVSM--EIGSNVTLPCYVQGYPEPTIKW 826
Query: 62 KK-DNIVIGAG--GKRFITE--NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
++ DN+ I + I++ G L I L D+G Y C A+NQ+G +S + V
Sbjct: 827 RRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTG 886
Query: 117 APRFLEKLPPRITAQVNSV-VFLHCNADV-DPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
L + P + + + L C +PI + + IK+S+ L N I
Sbjct: 887 LVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW--------IKNSAMLLQNPYIT 938
Query: 175 I-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILG-IQRSSV 232
+ G L I V L D G+Y CV + G + + + P G QIL I+ V
Sbjct: 939 VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPV 998
Query: 233 TLEWTDSNSNGRP 245
TL ++ N +P
Sbjct: 999 TLP-CKASGNPKP 1010
Score = 64.9 bits (151), Expect = 9e-10
Identities = 55/223 (24%), Positives = 84/223 (37%), Gaps = 10/223 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +L + + PS K + + + L+C+ P P TW
Sbjct: 1523 YQCTVSNAAGKQAKDIKLTIY-IPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD I + + + G + I + D YTC N GT E + V P
Sbjct: 1582 YKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMI 1641
Query: 121 LEKLPPRITAQVNSV--VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
L + QV + L C A +P W +G+ +K + ++ RI+ G
Sbjct: 1642 EGNLATPLNKQVVIAHSLTLECKAAGNP--SPILTWLKDGVPVKANDNI----RIEAGGK 1695
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGG 221
+L I + D G Y CV S G ++ + PP GG
Sbjct: 1696 KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGG 1738
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 3528
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 3529 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 3581
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 3582 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 3641
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 3642 E-CKSDAVPPPVITWLRNG 3659
Score = 64.1 bits (149), Expect = 2e-09
Identities = 59/235 (25%), Positives = 91/235 (38%), Gaps = 17/235 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + V+ + P+ + L T EG VTL CK PKP+ W
Sbjct: 958 YTCVASNVAGTNNKTTSV-VVHVLPTIQHGQQILSTI--EGIPVTLPCKASGNPKPSVIW 1014
Query: 62 KKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K +I +F +G+L + ++ G Y C A N G + + +L V PR
Sbjct: 1015 SKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRV 1074
Query: 121 L-------EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ P I+ V L C +V + W I S +
Sbjct: 1075 FGDQRGLSQDKPVEISVLAGEEVTLPC--EVKSLPPPIITWAKETQLISPFSP----RHT 1128
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ G + I SD G Y CV + G ++ V+L + PP G + L +Q
Sbjct: 1129 FLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQ 1183
Score = 63.3 bits (147), Expect = 3e-09
Identities = 60/231 (25%), Positives = 100/231 (43%), Gaps = 13/231 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N ++ V + P+ K L E + V L+C P P+ T
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTV-HVPPTIKSSGLS-ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 61 WKKDNIVIG-AGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
W KD+ + A G I +G ++ I + +D G YTCVA N G + +L V P
Sbjct: 1860 WLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-HEP 1918
Query: 119 RFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
LE + T V++ V L C A +P+ + + N L +S ++N+
Sbjct: 1919 PSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITW-YKDNRLLSGSTSMTFLNR----- 1972
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGI 227
G + I + +SD G Y+CV ++ G L++ P G ++ +
Sbjct: 1973 GQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAV 2023
Score = 62.5 bits (145), Expect = 5e-09
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 7/223 (3%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N ++ LR + K ++ E + G ++CK P P
Sbjct: 678 IYGCLASNSAGTDKQNSTLRYIEAP---KLMVVQSELLVALGDITVMECKTSGIPPPQVK 734
Query: 61 WKKDNIVIGAGGKRFITENGNLIIRQLSRD-DEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K ++ + I L+ Q ++D D G YTCVA N+ G + L V P
Sbjct: 735 WFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPV 794
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
F+++ P ++ ++ S V L C P + W S V+ ++ G
Sbjct: 795 FIQE-PADVSMEIGSNVTLPCYVQGYP--EPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
L I N+ SD G Y C ++ G+I S + + G P G+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGI 894
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 3418
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 3419 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 3478
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 3479 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 3527
Score = 61.3 bits (142), Expect = 1e-08
Identities = 46/175 (26%), Positives = 74/175 (42%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQ 102
++TL+CK P P TW KD + + A I G L I D G Y CVA +
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSV 1717
Query: 103 YGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G E + + VL P VN+++ L C+ P +W +G ++
Sbjct: 1718 AGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHVTGSP--PPTIMWLKDG-QL 1774
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D D + +I ++G +L I +S+ G Y C+ + G ++ + PP
Sbjct: 1775 IDERDGF---KILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 59.7 bits (138), Expect = 3e-08
Identities = 58/222 (26%), Positives = 83/222 (37%), Gaps = 16/222 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C +N L VL ++ LE + E +VTL C+ P P TW
Sbjct: 2455 YTCVVRNAAGEERKIFGLSVLVPPHIVGENTLE-DVKVKEKQSVTLTCEVTGNPVPEITW 2513
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + I G + I + G YTC+A + G L V +P
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573
Query: 121 L----EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI- 175
+ P +T +NS L C A P W KD + L N+ I+I
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYP--PATITW------FKDGTPLESNRNIRIL 2625
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I N + G Y CV + G + H ++++ PP
Sbjct: 2626 PGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPP 2667
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 3229 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 3286
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 3287 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Score = 58.8 bits (136), Expect = 6e-08
Identities = 49/180 (27%), Positives = 76/180 (42%), Gaps = 16/180 (8%)
Query: 46 TLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYG 104
+L C+ + P T TW KD + + I G + I D+ G Y+CVA N+ G
Sbjct: 2594 SLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Query: 105 TDESRGRLIVLRAPRFLEK--------LPPRITAQVNSVVFLHCNADVDPILDTAYLWNH 156
+ + + + P + K P + +VN+ + L C A P + W
Sbjct: 2654 -EMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIP--SASLSWYK 2710
Query: 157 NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+G +K SD +VN I +G L I +SD G Y CV + G + I+ PP
Sbjct: 2711 DGQPLK--SDDHVN--IAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 13/214 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL-KPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+NQ S + V L P P EG +TL C A P P
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVI--EGQQLTLPCTLLAGNPIPER 922
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W K++ ++ + +G+L I ++ D G YTCVA N GT+ ++V P
Sbjct: 923 RWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPT 982
Query: 120 FLEKLPPRITAQVNSV-VFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ +I + + + V L C A +P + +W+ G I SS + G
Sbjct: 983 I--QHGQQILSTIEGIPVTLPCKASGNP--KPSVIWSKKGELISTSSAKFSAGA----DG 1034
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
L + + + G+Y C + G VQL +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.6 bits (133), Expect = 1e-07
Identities = 52/221 (23%), Positives = 85/221 (38%), Gaps = 11/221 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGN--VTLKCKPEAAPKPT 58
+Y C A N + L V P T+ N + C + PKPT
Sbjct: 1238 IYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPT 1297
Query: 59 FTWKKDNIVI-GAGGKRFITENGNL-IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W + + G I E+G L +I ++ D G Y CVA N+ GT E + L V
Sbjct: 1298 IKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHV 1357
Query: 117 APRFLEK-LPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
P +K ++ +N + L C + P +W + +++ +SS + KI
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP--SPIIMWYKDNVQVTESSTIQTVNNGKI 1415
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L ++ + D G Y C + G + + + PP
Sbjct: 1416 ----LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPP 1452
Score = 57.2 bits (132), Expect = 2e-07
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 9/182 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGA--GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQ 102
V L+C+ P P+ TW KD + + G + ++ L + D G YTCVA N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNA 2088
Query: 103 YGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + L V P + + ++ ++ V L C +D P +L + + L K
Sbjct: 2089 AGEKQRDIDLRVYVPPNIMGE-EQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKK 2147
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGV 222
+ N+ + L I + + D G Y C + G+ + + I PP G
Sbjct: 2148 PGLSISENRSV------LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201
Query: 223 QI 224
++
Sbjct: 2202 EL 2203
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/262 (25%), Positives = 103/262 (39%), Gaps = 21/262 (8%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A N S + VL + P+ E +V L+C+ + P P W
Sbjct: 1429 YSCKAINIAGTSQKYFNIDVL-VPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHW 1487
Query: 62 KKDN--IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
KD + +G + L ++ R+D+G Y C N G +L + P
Sbjct: 1488 FKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS 1547
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD-LYVNKRIKIDG 177
+ I+ +NS++ L C P+ A W +G I SS LY++K G
Sbjct: 1548 IKGGNVTTDISVLINSLIKLECETRGLPM--PAITWYKDGQPIMSSSQALYIDK-----G 1600
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQL----RIEGPPGPPGGVQILGIQRSS 231
L I +SD Y C V + G S HV + IEG P Q+ + S
Sbjct: 1601 QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV--VIAHS 1658
Query: 232 VTLEWTDSNSNGRPITGYMLTG 253
+TLE + N PI ++ G
Sbjct: 1659 LTLE-CKAAGNPSPILTWLKDG 1679
Score = 52.8 bits (121), Expect = 4e-06
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 20/185 (10%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGN-LIIRQLSRDDEGVYTCVAKNQY 103
+TL+C+ A P + +W KD + + I NG+ L I++ D G YTCVA N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 104 GTDESRGRLIVLRAPRF--LEKLPPRITAQ---------VNSVVFLHCNADVDPILDTAY 152
G DE + + P F L ++ + +N+ + L+C + P
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP--PPTL 2809
Query: 153 LWNHNGLRIKDSSDLYVNKRIKIDGGE-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
W +G + S +K + + GG L I + D G Y CV + G S +R
Sbjct: 2810 TWYKDGHPLTSS-----DKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVR 2864
Query: 212 IEGPP 216
+ PP
Sbjct: 2865 VLVPP 2869
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 4417 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 4473
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 4474 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/170 (21%), Positives = 74/170 (43%), Gaps = 6/170 (3%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C ++ T ++ ++ + +G + + NL I +++ DEG Y C+A + GT
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTG 508
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
++ V P ++ +P +T L C + +D W N ++ +
Sbjct: 509 RAQTFFDVSEPPPVIQ-VPNNVTVTPGERAVLTCL--IISAVDYNLTWQRNDRDVRLAEP 565
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ + L + +V +D G+Y C+V S G ++ V L ++ PP
Sbjct: 566 ARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 39.5 bits (88), Expect = 0.038
Identities = 48/177 (27%), Positives = 74/177 (41%), Gaps = 11/177 (6%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKK-DNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVA 99
G L C +A TW++ D V A R T N +L ++ + +D G Y C+
Sbjct: 534 GERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMV 593
Query: 100 KNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGL 159
++ G+ + L V P+ + +P + S V + C+A P A W N +
Sbjct: 594 SSEGGSSAASVFLTVQEPPK-VTVMPKNQSFTGGSEVSIMCSATGYPKPKIA--WTVNDM 650
Query: 160 RIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR-IEGP 215
I S R+ D G L I N + D G Y C+ ++ G + LR IE P
Sbjct: 651 FIVGSH----RYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 91.9 bits (218), Expect = 7e-18
Identities = 63/218 (28%), Positives = 97/218 (44%), Gaps = 17/218 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V L P+F + P ++ ++G + L CK P P TW
Sbjct: 1275 YTCVANNAAGEDTHTVSLTVHVL-PTFTELPGDVSL--NKGEQLRLSCKATGIPLPKLTW 1331
Query: 62 KKDNIVIGAGGKRFITENGN--LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
+N +I A F + NG+ L+I ++S++D G Y C A+N G ++ G + V P
Sbjct: 1332 TFNNNIIPA---HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV 1388
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK-IDGG 178
F P + L+C DP WN G+ D+ ++ RI+ + G
Sbjct: 1389 FKGDYPSHWIEPLGGNAILNCEVKGDP--TPTIQWNRKGV------DIEISHRIRQLGNG 1440
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L IY D GDY CV + G + + L ++ PP
Sbjct: 1441 SLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPP 1478
Score = 85.4 bits (202), Expect = 6e-16
Identities = 65/216 (30%), Positives = 92/216 (42%), Gaps = 9/216 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + + +++ P+ K P L ++ + L+C E P P TW
Sbjct: 728 YTCVASN-IAGKTTREFILTVNVPPNIKGGPQSLVILLNK--STVLECIAEGVPTPRITW 784
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+KD V+ R+ I ENG L I+ D G Y C+A N GTD R L V P
Sbjct: 785 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV-HVPPS 843
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+ P +T VN L C A P + W NG + + D N + G L
Sbjct: 844 IAPGPTNMTVIVNVQTTLACEATGIP--KPSINWRKNGHLL--NVDQNQNSYRLLSSGSL 899
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I + S+ D YEC V + G V L ++ PP
Sbjct: 900 VIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 935
Score = 84.6 bits (200), Expect = 1e-15
Identities = 62/216 (28%), Positives = 96/216 (44%), Gaps = 12/216 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N +++ L V P + P EL + + L C+ P P TW
Sbjct: 1003 YTCVARNAAGSAHRHVTLHVHE-PPVIQPQPSELHVILNNP--ILLPCEATGTPSPFITW 1059
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
+K+ I + G+ + +G L I + R+D G Y CVA+N GT + +L V P
Sbjct: 1060 QKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI 1119
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
L + A V+ + L C AD P D W+ +G I +S + +R+ + G L
Sbjct: 1120 SPHLKEYVIA-VDKPITLSCEADGLPPPDIT--WHKDGRAIVES----IRQRV-LSSGSL 1171
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I V D G Y C+ + G S+ +L + PP
Sbjct: 1172 QITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPP 1207
Score = 83.0 bits (196), Expect = 3e-15
Identities = 69/222 (31%), Positives = 98/222 (44%), Gaps = 8/222 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS--EGGNVTLKCKPEAAPKPTF 59
Y C A NQ S L V + PS K H E + + EG +V+L+ + A P P
Sbjct: 71 YTCIAINQAGESKKKFSLTVY-VPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVI 129
Query: 60 TWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
TW K+ +I I +G ++ I++ D G Y C A N G D+ L V P
Sbjct: 130 TWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPP 189
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
I +++ V L C+A P A+L NH RI++S L V RI G
Sbjct: 190 SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHK--RIENSDSLEV--RILSGGS 245
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+L I SD G+Y C+ + G+ + L I+ PP G
Sbjct: 246 KLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG 287
Score = 80.2 bits (189), Expect = 2e-14
Identities = 63/216 (29%), Positives = 93/216 (43%), Gaps = 13/216 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N +S +S +L V + P + E +E L C + P P W
Sbjct: 1184 YTCMAANVAGSSSTSTKLTV-HVPPRIRS--TEGHYTVNENSQAILPCVADGIPTPAINW 1240
Query: 62 KKDNIVIG-AGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KKDN+++ GK G LI+ + +D G YTCVA N G D L V P F
Sbjct: 1241 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTF 1300
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
E LP ++ + L C A P+ + +N+N + S VN EL
Sbjct: 1301 TE-LPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDS---VNGH-----SEL 1351
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
I VS D G Y C ++++G + + + ++ PP
Sbjct: 1352 VIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 1387
Score = 77.8 bits (183), Expect = 1e-13
Identities = 61/215 (28%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N + +L V + P H E + +TL C+ + P P TW
Sbjct: 1094 YMCVAQNPAGTALGKIKLNV-QVPPVISPHLKEYVIAVDKP--ITLSCEADGLPPPDITW 1150
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFL 121
KD I ++ + +G+L I + D G YTC+A N G+ + +L V PR +
Sbjct: 1151 HKDGRAIVESIRQRVLSSGSLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPR-I 1209
Query: 122 EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELT 181
T NS L C AD P A W + + + + Y + GEL
Sbjct: 1210 RSTEGHYTVNENSQAILPCVADGIP--TPAINWKKDNVLLANLLGKYTAEPY----GELI 1263
Query: 182 IYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ NV L D G Y CV +A G + V L + P
Sbjct: 1264 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLP 1298
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 13/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N L+V + PS P + + TL C+ PKP+ W
Sbjct: 819 YLCMATNAAGTDRRRIDLQV-HVPPSIAPGPTNMTVIVNV--QTTLACEATGIPKPSINW 875
Query: 62 KKDNIVIGAGGKRF---ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+K+ ++ + + +G+L+I S DD Y C N G D+ L V P
Sbjct: 876 RKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPP 935
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
++ P ++ + C A P + W NG+R+ D Y RI + G
Sbjct: 936 SIADE-PTDFLVTKHAPAVITCTASGVPF--PSIHWTKNGIRLLPRGDGY---RI-LSSG 988
Query: 179 ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ I L+ G Y CV ++A G HV L + PP
Sbjct: 989 AIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPP 1026
Score = 71.7 bits (168), Expect = 8e-12
Identities = 47/172 (27%), Positives = 74/172 (43%), Gaps = 8/172 (4%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
GGN L C+ + P PT W + + I + NG+L I +D G YTCVA N
Sbjct: 1402 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 1461
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
+ G E R + L++P + P + L+C A +P W+ G I
Sbjct: 1462 EAGVVE-RSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEP--QPTITWSRQGHSI 1518
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
S D VN + L I + D ++ECV ++ +G + V + ++
Sbjct: 1519 --SWDDRVN---VLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 1565
Score = 69.3 bits (162), Expect = 4e-11
Identities = 64/235 (27%), Positives = 88/235 (37%), Gaps = 9/235 (3%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ L+VL P E + L C P P TW
Sbjct: 542 YTCIASNEAGEVSKHFILKVLE-PPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTW 600
Query: 62 KKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
KD + + G ++ I +D G YTC+A + G D+ + V P
Sbjct: 601 MKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNI 660
Query: 121 LEKLPPR-ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
PR IT N V L C +D P W NG R++ + + RI G
Sbjct: 661 AGTDEPRDITVLRNRQVTLECKSDAVP--PPVITWLRNGERLQATPRV----RILSGGRY 714
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
L I N L D +Y CV + G+ + L + PP GG Q L I + T+
Sbjct: 715 LQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTV 769
Score = 65.7 bits (153), Expect = 5e-10
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 12/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N ++ + + PS + + G NV L C P P W
Sbjct: 260 YTCIASN-MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW 318
Query: 62 KKDNIVIGAGGKRFITENGN---LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
KD I +G I + N L I D G YTCVA N G ++ L V P
Sbjct: 319 LKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 378
Query: 119 --RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKID 176
R + ++ V++ + + C A P W NGL + SS + R+
Sbjct: 379 TIRGNKDEAEKLMTLVDTSINIECRATGTP--PPQINWLKNGLPLPLSSHI----RLLAA 432
Query: 177 GGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G + I +SDV Y CV + G + H L++ PP
Sbjct: 433 GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPP 472
Score = 64.9 bits (151), Expect = 9e-10
Identities = 60/259 (23%), Positives = 104/259 (40%), Gaps = 15/259 (5%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A N+ L+V + P+ E +G + ++ C + P P+
Sbjct: 448 VYTCVASNRAGVDNKHYNLQVFA-PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 506
Query: 61 WKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W +D +G ++ +G ++ + + +D G YTC+A N+ G L VL P
Sbjct: 507 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH 566
Query: 120 FL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGG 178
+ I+ VN+ + L C A P W +G + + + + GG
Sbjct: 567 INGSEEHEEISVIVNNPLELTCIASGIPA--PKMTWMKDGRPLPQTDQVQT-----LGGG 619
Query: 179 E-LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQ---ILGIQRSSVTL 234
E L I + D G Y C+ S G +R+ PP G + I ++ VTL
Sbjct: 620 EVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTL 679
Query: 235 EWTDSNSNGRPITGYMLTG 253
E S++ P+ ++ G
Sbjct: 680 E-CKSDAVPPPVITWLRNG 697
Score = 62.1 bits (144), Expect = 6e-09
Identities = 43/175 (24%), Positives = 69/175 (39%), Gaps = 8/175 (4%)
Query: 44 NVTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQ 102
++ ++C+ P P W K+ + + + G +I I + D VYTCVA N+
Sbjct: 397 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNR 456
Query: 103 YGTDESRGRLIVLRAPRFLEKL-PPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G D L V P + IT S + C D P A+L + L +
Sbjct: 457 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGL 516
Query: 162 KDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D ++ + G L + D G Y C+ + G +S H L++ PP
Sbjct: 517 ----DAHLT--VSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPP 565
Score = 59.7 bits (138), Expect = 3e-08
Identities = 45/162 (27%), Positives = 64/162 (39%), Gaps = 8/162 (4%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGK---RFITENGNLIIRQLSRDDEGVYTCVAKN 101
VTL C P PT W K++ I R ++ L I + D G YTC+A N
Sbjct: 207 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 266
Query: 102 QYGTDESRGRLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
G + L + P ++P ++ + V L CNA+ P W +G
Sbjct: 267 MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPT--PLIQWLKDGKP 324
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
I + R+ +G L IY SD G Y CV + G
Sbjct: 325 IASGETERI--RVSANGSTLNIYGALTSDTGKYTCVATNPAG 364
Score = 59.3 bits (137), Expect = 4e-08
Identities = 44/178 (24%), Positives = 68/178 (38%), Gaps = 6/178 (3%)
Query: 45 VTLKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAKNQY 103
++L C+ P P +W K+ I I G + I + D G YTC+A NQ
Sbjct: 20 ISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQA 79
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRIT-AQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G + + L V P + ++ V + + + + W NG I
Sbjct: 80 GESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMIT 139
Query: 163 DSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPG 220
+S+ + I DG L I +SD G Y C + GR + L + PP G
Sbjct: 140 ESTHV----EILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEG 193
Score = 52.8 bits (121), Expect = 4e-06
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 3/113 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+ S L + S P P+E T + GG + L C+ P+PT TW
Sbjct: 1455 YTCVATNEAGVVERSMSLTLQS-PPIITLEPVE--TVINAGGKIILNCQATGEPQPTITW 1511
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
+ I + + N +L I ++D + CVA+N G+ R +IV
Sbjct: 1512 SRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 1564
Score = 39.5 bits (88), Expect = 0.038
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 12/138 (8%)
Query: 128 ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSL 187
+T VN+ + L C P D ++L N +++ N I G L I +
Sbjct: 12 LTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLN------TNTLIVPGGRTLQIIRAKV 65
Query: 188 SDVGDYECVVKSAIGRISSHVQLRIEGPPG----PPGGVQILGIQR-SSVTLEWTDSNSN 242
SD G+Y C+ + G L + PP + ++ ++ +SV+LE +SN+
Sbjct: 66 SDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLE-XESNAV 124
Query: 243 GRPITGYMLTGRTHWNST 260
P+ + GR ST
Sbjct: 125 PPPVITWYKNGRMITEST 142
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 91.5 bits (217), Expect = 9e-18
Identities = 59/215 (27%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + +++A + V +L P F P + EG V +C+ + P P W
Sbjct: 427 YACSATNNIDSVHATAFIIVQAL-PQFTVTPQDRVVI--EGQTVDFQCEAKGNPPPVIAW 483
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K + + + +G L I ++ D+G Y C A N G+ + L V R
Sbjct: 484 TKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV 543
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+P T +V + V L C++ +P + A WN +G+++ +S +++ G L
Sbjct: 544 FASIPSDTTVEVGANVQLPCSSQGEP--EPAITWNKDGVQVTESGKFHISPE-----GFL 596
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
TI +V +D G YECV ++ IG S + L + P
Sbjct: 597 TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 74.1 bits (174), Expect = 1e-12
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 18/218 (8%)
Query: 1 MYQCEAKN---QLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC AKN ++K + + +P+F P E E +VTL+C P P
Sbjct: 331 IYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGE--SVTLECSATGHPPP 388
Query: 58 TFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+W + D + + IT +G L I+ + + D G Y C A N + + +IV
Sbjct: 389 RISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR-IKI 175
P+F R+ + +V F C A +P W G S L V++R + +
Sbjct: 449 LPQFTVTPQDRVVIEGQTVDF-QCEAKGNP--PPVIAWTKGG------SQLSVDRRHLVL 499
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIG--RISSHVQLR 211
G L I V+L D G YEC + IG ++ +H+ ++
Sbjct: 500 SSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 537
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/201 (25%), Positives = 85/201 (42%), Gaps = 21/201 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDN--IVIGAGGKRFITENGNL 82
+P P + + + G V C+ E PKP W ++N + + + + ++G L
Sbjct: 262 RPRITSEPQDADV--TSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTL 319
Query: 83 IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR------APRFLEKLPPRITAQVNSVV 136
+I+ D+G+Y C+AKN G E + + + LR P F+ + P V V
Sbjct: 320 MIQNTQETDQGIYQCMAKNVAG--EVKTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESV 376
Query: 137 FLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYEC 195
L C+A P W D + L V+ R+ I G L I NV D G+Y C
Sbjct: 377 TLECSATGHP--PPRISWTRG-----DRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYAC 429
Query: 196 VVKSAIGRISSHVQLRIEGPP 216
+ I + + + ++ P
Sbjct: 430 SATNNIDSVHATAFIIVQALP 450
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 91.5 bits (217), Expect = 9e-18
Identities = 59/215 (27%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + +++A + V +L P F P + EG V +C+ + P P W
Sbjct: 405 YACSATNNIDSVHATAFIIVQAL-PQFTVTPQDRVVI--EGQTVDFQCEAKGNPPPVIAW 461
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K + + + +G L I ++ D+G Y C A N G+ + L V R
Sbjct: 462 TKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV 521
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+P T +V + V L C++ +P + A WN +G+++ +S +++ G L
Sbjct: 522 FASIPSDTTVEVGANVQLPCSSQGEP--EPAITWNKDGVQVTESGKFHISPE-----GFL 574
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
TI +V +D G YECV ++ IG S + L + P
Sbjct: 575 TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 609
Score = 74.1 bits (174), Expect = 1e-12
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 18/218 (8%)
Query: 1 MYQCEAKN---QLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC AKN ++K + + +P+F P E E +VTL+C P P
Sbjct: 309 IYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGE--SVTLECSATGHPPP 366
Query: 58 TFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+W + D + + IT +G L I+ + + D G Y C A N + + +IV
Sbjct: 367 RISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 426
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR-IKI 175
P+F R+ + +V F C A +P W G S L V++R + +
Sbjct: 427 LPQFTVTPQDRVVIEGQTVDF-QCEAKGNP--PPVIAWTKGG------SQLSVDRRHLVL 477
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIG--RISSHVQLR 211
G L I V+L D G YEC + IG ++ +H+ ++
Sbjct: 478 SSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 515
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/201 (25%), Positives = 85/201 (42%), Gaps = 21/201 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDN--IVIGAGGKRFITENGNL 82
+P P + + + G V C+ E PKP W ++N + + + + ++G L
Sbjct: 240 RPRITSEPQDADV--TSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTL 297
Query: 83 IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR------APRFLEKLPPRITAQVNSVV 136
+I+ D+G+Y C+AKN G E + + + LR P F+ + P V V
Sbjct: 298 MIQNTQETDQGIYQCMAKNVAG--EVKTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESV 354
Query: 137 FLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYEC 195
L C+A P W D + L V+ R+ I G L I NV D G+Y C
Sbjct: 355 TLECSATGHP--PPRISWTRG-----DRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYAC 407
Query: 196 VVKSAIGRISSHVQLRIEGPP 216
+ I + + + ++ P
Sbjct: 408 SATNNIDSVHATAFIIVQALP 428
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 91.5 bits (217), Expect = 9e-18
Identities = 59/215 (27%), Positives = 100/215 (46%), Gaps = 11/215 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + +++A + V +L P F P + EG V +C+ + P P W
Sbjct: 427 YACSATNNIDSVHATAFIIVQAL-PQFTVTPQDRVVI--EGQTVDFQCEAKGNPPPVIAW 483
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL-RAPRF 120
K + + + +G L I ++ D+G Y C A N G+ + L V R
Sbjct: 484 TKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPV 543
Query: 121 LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGEL 180
+P T +V + V L C++ +P + A WN +G+++ +S +++ G L
Sbjct: 544 FASIPSDTTVEVGANVQLPCSSQGEP--EPAITWNKDGVQVTESGKFHISPE-----GFL 596
Query: 181 TIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGP 215
TI +V +D G YECV ++ IG S + L + P
Sbjct: 597 TINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 74.1 bits (174), Expect = 1e-12
Identities = 60/218 (27%), Positives = 97/218 (44%), Gaps = 18/218 (8%)
Query: 1 MYQCEAKN---QLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKP 57
+YQC AKN ++K + + +P+F P E E +VTL+C P P
Sbjct: 331 IYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGE--SVTLECSATGHPPP 388
Query: 58 TFTWKK-DNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+W + D + + IT +G L I+ + + D G Y C A N + + +IV
Sbjct: 389 RISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA 448
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR-IKI 175
P+F R+ + +V F C A +P W G S L V++R + +
Sbjct: 449 LPQFTVTPQDRVVIEGQTVDF-QCEAKGNP--PPVIAWTKGG------SQLSVDRRHLVL 499
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIG--RISSHVQLR 211
G L I V+L D G YEC + IG ++ +H+ ++
Sbjct: 500 SSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 537
Score = 60.9 bits (141), Expect = 1e-08
Identities = 51/201 (25%), Positives = 85/201 (42%), Gaps = 21/201 (10%)
Query: 25 KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTWKKDN--IVIGAGGKRFITENGNL 82
+P P + + + G V C+ E PKP W ++N + + + + ++G L
Sbjct: 262 RPRITSEPQDADV--TSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTL 319
Query: 83 IIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR------APRFLEKLPPRITAQVNSVV 136
+I+ D+G+Y C+AKN G E + + + LR P F+ + P V V
Sbjct: 320 MIQNTQETDQGIYQCMAKNVAG--EVKTQEVTLRYFGSPARPTFVIQ-PQNTEVLVGESV 376
Query: 137 FLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYEC 195
L C+A P W D + L V+ R+ I G L I NV D G+Y C
Sbjct: 377 TLECSATGHP--PPRISWTRG-----DRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYAC 429
Query: 196 VVKSAIGRISSHVQLRIEGPP 216
+ I + + + ++ P
Sbjct: 430 SATNNIDSVHATAFIIVQALP 450
>AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein.
Length = 980
Score = 91.1 bits (216), Expect = 1e-17
Identities = 124/501 (24%), Positives = 200/501 (39%), Gaps = 69/501 (13%)
Query: 104 GTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKD 163
G S L L AP + + P ++ S C A +P A W HNG ++
Sbjct: 51 GIPRSASPLAPLAAPA-ITQAPEALSRTRASTARFVCRASGEP--RPALRWLHNGAPLRP 107
Query: 164 SSDLYVNKRIKIDGG--ELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI---EGPPGP 218
N R+K+ GG L I + L D G Y+CV +++ G + L + EG P
Sbjct: 108 ------NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSA 161
Query: 219 PGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYN 278
P V + S+V + W + I G+ L H+ + + NV N
Sbjct: 162 PTRVTATPLSSSAVLVAWERPEMHSEQIIGFSL----HYQK-----ARGMDNVEYQFAVN 212
Query: 279 GRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKT 338
L P YEF + A + LG + S P+ T D P AP +S
Sbjct: 213 NDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPA-LVHTLDDVPSAAP-QLSLSSPNP 270
Query: 339 GDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYT 398
D+ + W PLP SL NG + YKI + G E Q + GN T ++ ++S
Sbjct: 271 SDIRVAWLPLPPSLSNGQVVKYKIEY---GLGKEDQIFSTEVRGN-ETQLM-LNSLQPNK 325
Query: 399 PYDVKVQAFNDIGPGPESE-----VVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPID 453
Y V++ A G G S+ ++++ +P AP + ++ +L V+W P
Sbjct: 326 VYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVP-FAPAELKVQA-KMESLVVSWQPPP 383
Query: 454 QSRERLRGKLIGHRLKYWKQENKEEEC---IYYLSRTTRNWAL-------------IVGL 497
+ + G++L YW++ EEE R + W + + L
Sbjct: 384 HPTQ-----ISGYKL-YWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQL 437
Query: 498 QPDTYYYVKVMAFNSAGEG--------PESERYLERTFRKAPQKPPASVNVWAHDPTTLR 549
P Y VK++AFN +G E + ++ P PPA V+ ++ T++
Sbjct: 438 VPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAESNSSTSIW 497
Query: 550 VVWRYVQPTNEEEPLLGYKVR 570
+ W+ +P ++ Y VR
Sbjct: 498 LRWK--KPDFTTVKIVNYTVR 516
Score = 68.1 bits (159), Expect = 9e-11
Identities = 121/550 (22%), Positives = 208/550 (37%), Gaps = 51/550 (9%)
Query: 49 CKPEAAPKPTFTWKKDNIVIGAGGKRFITENG-NLIIRQLSRDDEGVYTCVAKNQYGTDE 107
C+ P+P W + + G+ + G +L+I Q+ D G Y CVA+N G
Sbjct: 86 CRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMAC 145
Query: 108 SRGRLIVLRAPRFLEKLPPRITA-QVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
+ L V+ L P R+TA ++S L + + ++ + + + +
Sbjct: 146 AAASLAVV-VREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDN 204
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG--RISSHVQLR-IEGPPGPPGGVQ 223
+ + D EL + ++ + ++ V S +G R S+ + ++ P +
Sbjct: 205 VEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQLS 264
Query: 224 ILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRA 283
+ S + + W P+ + G+ Y + + + + G +
Sbjct: 265 LSSPNPSDIRVAWL-------PLPPSLSNGQVVKYKIEYGLGKE-DQIFSTE-VRGNETQ 315
Query: 284 TVSTTLLPWAIYEFRIQAINILGPGQPSA----PSPQFSTSGDKPYEAPANVSGGGGKTG 339
+ +L P +Y RI A G G PS +P P+ APA + K
Sbjct: 316 LMLNSLQPNKVYRVRISAGTAAGFGAPSQWMHHRTPSMHNQSHVPF-APAELK-VQAKME 373
Query: 340 DLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLL-----KKYGNIGTYVVHIS-S 393
L ++W P P Q YK++WR G+E E L + ++G +
Sbjct: 374 SLVVSWQPPPHPTQIS---GYKLYWREVGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVK 430
Query: 394 TYFYTP------YDVKVQAFNDIGPGPES---EVVTIYSAEDMP-QVAPQL----VSARS 439
Y T Y+VK+ AFN G + A DMP Q P L V A S
Sbjct: 431 QYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLPPAHVHAES 490
Query: 440 FNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQP 499
+ST++ + W D + ++ + R W N YY S + LI GL+P
Sbjct: 491 NSSTSIWLRWKKPDFTTVKIVNYTV--RFSPWGLRN-ASLVTYYTS--SGEDILIGGLKP 545
Query: 500 DTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTN 559
T Y V + +GP T P PP+ + + P+T+R+ W PT
Sbjct: 546 FTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHW--CPPTE 603
Query: 560 EEEPLLGYKV 569
++ Y +
Sbjct: 604 PNGEIVEYLI 613
Score = 67.7 bits (158), Expect = 1e-10
Identities = 60/239 (25%), Positives = 110/239 (46%), Gaps = 27/239 (11%)
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
T Y+ V A++ +G S +++ +D+P APQL S S N + + V W P+ S
Sbjct: 227 TDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAPQL-SLSSPNPSDIRVAWLPLPPSLS 285
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGP 517
G+++ ++++Y KE++ R ++ LQP+ Y V++ A +AG G
Sbjct: 286 N--GQVVKYKIEYGL--GKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISAGTAAGFGA 341
Query: 518 ESERYLERTFRKAPQK----PPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWE 573
S+ RT Q PA + V A +L V W QP + GYK+ E
Sbjct: 342 PSQWMHHRTPSMHNQSHVPFAPAELKVQA-KMESLVVSW---QPPPHPTQISGYKLYWRE 397
Query: 574 LDQDMSTANDTI-------------VPIEHKLEAY-ISNIIPGKSYNLRVLAYSNGGDG 618
+ + D + V ++ K++ Y ++ ++PG+ Y ++++A++ DG
Sbjct: 398 VGAEEEANGDRLPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDG 456
Score = 58.8 bits (136), Expect = 6e-08
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 15/213 (7%)
Query: 214 GPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVME 273
GPP PP V +S+ L W + I Y + S W + N
Sbjct: 478 GPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRF-----SPW-----GLRNASL 527
Query: 274 VDRYNGRKRATVSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG 333
V Y + L P+ YEF +Q+ + G P + ST D+P P+++
Sbjct: 528 VTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDG-PFGSVVERSTLPDRPSTPPSDLRL 586
Query: 334 GGGKTGDLTITWTPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISS 393
+ + W P PT NG + Y I + N ++ E Q LL GNI + VH
Sbjct: 587 SPLTPSTVRLHWCP-PTE-PNGEIVEYLILYSSNHTQPEHQWTLLTTQGNIFSAEVH--G 642
Query: 394 TYFYTPYDVKVQAFNDIGPGPESEVVTIYSAED 426
T Y K+ A ++GPGP S + + + ++
Sbjct: 643 LESDTRYFFKMGARTEVGPGPFSRLQDVITLQE 675
Score = 40.7 bits (91), Expect = 0.016
Identities = 34/142 (23%), Positives = 56/142 (39%), Gaps = 6/142 (4%)
Query: 495 VGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRY 554
+GLQ YY + +A NSAG + L R+ P V + + V W
Sbjct: 125 IGLQDAGYY--QCVAENSAGMACAAAS-LAVVVREGLPSAPTRVTATPLSSSAVLVAWE- 180
Query: 555 VQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYISNIIPGKSYNLRVLAYSN 614
+P E ++G+ + ++ + M E + ++ P Y V+AYS
Sbjct: 181 -RPEMHSEQIIGFSLH-YQKARGMDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQ 238
Query: 615 GGDGRMSSPTIAFQIGDYHSEA 636
G R S+P + + D S A
Sbjct: 239 LGASRTSTPALVHTLDDVPSAA 260
Score = 39.9 bits (89), Expect = 0.029
Identities = 55/244 (22%), Positives = 98/244 (40%), Gaps = 24/244 (9%)
Query: 287 TTLLPWAIYEFRIQAINILGPGQPS--------APSPQFSTSGDKPYEAPANVSGGGGKT 338
T L+P +YE ++ A N G + AP+P P PA+V +
Sbjct: 435 TQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPAPDMPIQRGPPLP-PAHVHAESNSS 493
Query: 339 GDLTITWT-PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFY 397
+ + W P T+++ ++Y + + G + L+ Y + G ++ I +
Sbjct: 494 TSIWLRWKKPDFTTVKI---VNYTVRFSPWGLR---NASLVTYYTSSGEDIL-IGGLKPF 546
Query: 398 TPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRE 457
T Y+ VQ+ GP VV + D P P + + + + W P +
Sbjct: 547 TKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPN- 605
Query: 458 RLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNW--ALIVGLQPDTYYYVKVMAFNSAGE 515
G+++ + + Y + + E + L T N A + GL+ DT Y+ K+ A G
Sbjct: 606 ---GEIVEYLILY-SSNHTQPEHQWTLLTTQGNIFSAEVHGLESDTRYFFKMGARTEVGP 661
Query: 516 GPES 519
GP S
Sbjct: 662 GPFS 665
>AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ40259 fis, clone TESTI2025486. ).
Length = 600
Score = 90.2 bits (214), Expect = 2e-17
Identities = 55/170 (32%), Positives = 83/170 (48%), Gaps = 5/170 (2%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ C PKP TW K+ ++GA GK + +G+L + +SR+D G YTC A + G
Sbjct: 1 MTCTAFGNPKPIVTWLKEGTLLGASGK-YQVSDGSLTVTSVSREDRGAYTCRAYSIQGEA 59
Query: 107 ESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD 166
L+V + P F+ P IT ++ L C A+ P + Y W + +D
Sbjct: 60 VHTTHLLV-QGPPFIVSPPENITVNISQDALLTCRAEAYP-GNLTYTWYWQDENVYFQND 117
Query: 167 LYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRI-SSHVQLRIEGP 215
L + RI ID G L I+ V D G Y CV +++GR S+ L ++ P
Sbjct: 118 LKLRVRILID-GTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYP 166
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/180 (28%), Positives = 81/180 (45%), Gaps = 17/180 (9%)
Query: 47 LKCKPEAAP-KPTFTW--KKDNIVIGAGGKRF--ITENGNLIIRQLSRDDEGVYTCVAKN 101
L C+ EA P T+TW + +N+ K I +G LII ++ +D G YTCV N
Sbjct: 90 LTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSN 149
Query: 102 QYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRI 161
G S + ++ P + +PP I V ++ C D +P T WN
Sbjct: 150 SLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPA-TVVKWN------ 202
Query: 162 KDSSDLYVNKRI---KIDGGELTIYNVSLSDVGDYECVVKSAIGRI--SSHVQLRIEGPP 216
KD L V K + ++ G + I + +G Y CV + +G + S+ +L ++ PP
Sbjct: 203 KDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPP 262
Score = 41.5 bits (93), Expect = 0.009
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C N L SA R++ P + E G + + C P P TW
Sbjct: 237 YTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITW 296
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKN 101
+K + + K +G+L R LS++D G + CVA N
Sbjct: 297 RK--VGKPSRSKHSALPSGSLQFRALSKEDHGEWECVATN 334
Score = 35.9 bits (79), Expect = 0.47
Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP---G 217
+K+ + L + + ++ G LT+ +VS D G Y C S G L ++GPP
Sbjct: 16 LKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVS 75
Query: 218 PPGGVQI 224
PP + +
Sbjct: 76 PPENITV 82
>AK074077-1|BAB84903.1| 572|Homo sapiens FLJ00148 protein protein.
Length = 572
Score = 85.4 bits (202), Expect = 6e-16
Identities = 61/217 (28%), Positives = 98/217 (45%), Gaps = 7/217 (3%)
Query: 397 YTPYDVKVQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSR 456
Y Y+V + A+N IG P S V ++ E P +APQ V ++ L VTW+P
Sbjct: 29 YRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDP--PPP 86
Query: 457 ERLRGKLIGHRLKYWKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEG 516
E G + G+++ YW+ +++ E + + L T Y V + AFN+AG+G
Sbjct: 87 ESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDG 146
Query: 517 PESERYLERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQ 576
P+S+ RT + AP P+ + TTL V W +P L GY+V L
Sbjct: 147 PKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWG--EPAAANGILQGYRVVYEPLAP 203
Query: 577 DMSTANDTIVPIEHKLEAY--ISNIIPGKSYNLRVLA 611
+ V + + + + ++ G +Y RV A
Sbjct: 204 VQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA 240
Score = 79.8 bits (188), Expect = 3e-14
Identities = 85/344 (24%), Positives = 135/344 (39%), Gaps = 17/344 (4%)
Query: 287 TTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWT 346
T L + YE + A NI+G SAP F P AP NV L +TW
Sbjct: 24 THLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEA-APAMAPQNVQVTPLTASQLEVTWD 82
Query: 347 PLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQA 406
P P QNG YKI++ S+ E + + K + VV + + +T Y V + A
Sbjct: 83 PPPPESQNGNIQGYKIYYWEADSQNETEKM---KVLFLPEPVVRLKNLTSHTKYLVSISA 139
Query: 407 FNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGH 466
FN G GP+S+ + + P AP ++ ST LNV+W G L G+
Sbjct: 140 FNAAGDGPKSDPQQGRTHQAAPG-APSFLAFSEITSTTLNVSWG----EPAAANGILQGY 194
Query: 467 RLKY---WKQENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYL 523
R+ Y + + + + W + L Y+ +V A + GPE + +
Sbjct: 195 RVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQA-RTITYGPELQANI 253
Query: 524 ERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTAND 583
+ P V V + L + W + + + P GY + D+ +
Sbjct: 254 TAGPAEGSPGSPRDVLV-TKSASELTLQW--TEGHSGDTPTTGYVIEARPSDEGLWDMFV 310
Query: 584 TIVP-IEHKLEAYISNIIPGKSYNLRVLAYSNGGDGRMSSPTIA 626
+P + + G +Y RV+A + G G S+P+ A
Sbjct: 311 KDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTA 354
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PG P V + S +TL+WT+ +S P TGY++ R W + ++IP
Sbjct: 259 EGSPGSPRDVLVTK-SASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPR-- 315
Query: 273 EVDRYNGRKRATVSTTLLPWAI-YEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
Y T+S L + YEFR+ A+N G G+PS PS S + P+
Sbjct: 316 SATSY------TLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAPF 363
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 83.4 bits (197), Expect = 2e-15
Identities = 67/219 (30%), Positives = 95/219 (43%), Gaps = 11/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V+S P + + T S G V LKC+ E P PT TW
Sbjct: 1721 YLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHS-GSTVELKCRAEGRPSPTVTW 1779
Query: 62 KKDNIVI---GAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
N + + G R +T +G L++ LS D G Y CVA N G D ++ V+
Sbjct: 1780 ILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIA 1839
Query: 117 APR-FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
AP LE+ I + L C A P + Y +G +K + N ++ +
Sbjct: 1840 APPVILEQRRQVIVGTWGESLKLPCTAKGTP-QPSVYWVLSDGTEVKPLQ--FTNSKLFL 1896
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
G L I N++ SD G YEC+ S+ G V L +E
Sbjct: 1897 FSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTME 1935
Score = 70.9 bits (166), Expect = 1e-11
Identities = 58/219 (26%), Positives = 90/219 (41%), Gaps = 10/219 (4%)
Query: 4 CEAKNQLKASYSSAQLRVLSL--KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
C A+N+ S QL VL + +P+F+ +P + G + L C + P P W
Sbjct: 2313 CVARNEGGESVLVVQLEVLEMLRRPTFR-NPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 2371
Query: 62 KKDNIVIGAGGKR----FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
N + G + I NG+ II + +R+D G Y C A+N+ G E L + +
Sbjct: 2372 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 2431
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P L P + + LHC +D P W + D + K I D
Sbjct: 2432 PVILTYAPGTVKGISGESLSLHCVSDGIP--KPNIKWTMPSGYVVDRPQIN-GKYILHDN 2488
Query: 178 GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I + D G+Y C ++++G V + I P
Sbjct: 2489 GTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYP 2527
Score = 69.3 bits (162), Expect = 4e-11
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRF-----ITENGNLIIRQLSRDDEGVYTCVAKN 101
L C+ P PT W + + ++ + NG L I+++ D G Y C A N
Sbjct: 1668 LPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASN 1727
Query: 102 QYGTDESRGRL-IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
+GTD L +V PR LE+ IT S V L C A+ P ++ N
Sbjct: 1728 LFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWIL-ANQTV 1786
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ +SS + +D G L ++N+S+ D G Y+CV + G+ S V++++ P
Sbjct: 1787 VSESSQGSRQAVVTVD-GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAP 1841
Score = 67.7 bits (158), Expect = 1e-10
Identities = 56/209 (26%), Positives = 94/209 (44%), Gaps = 13/209 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSL--KPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
Y+C A+N K Y +L +L + KP + G G +++L C + PKP
Sbjct: 2409 YRCAARN--KVGYIE-KLVILEIGQKPVILTYAPGT-VKGISGESLSLHCVSDGIPKPNI 2464
Query: 60 TWKKDNIVI----GAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYG-TDESRGRLIV 114
W + + GK + +NG L+I++ + D G Y C A+N G T + +IV
Sbjct: 2465 KWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIV 2524
Query: 115 LRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAY-LWNHNGLRIKDSSDLYVNKRI 173
PR + P I + + LHC A P + + + +H+ L + ++++
Sbjct: 2525 AYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQL 2584
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIG 202
+ G L I N SD G Y+C K+ +G
Sbjct: 2585 HLQ-GTLVIQNPQTSDSGIYKCTAKNPLG 2612
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/228 (26%), Positives = 91/228 (39%), Gaps = 18/228 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y C A+N++ + L LKP+ H G + + CK +P P +
Sbjct: 2013 VYLCVARNKMGDDLILMHVS-LRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEIS 2071
Query: 61 WK-KDNIVI---------GAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESR 109
W D +I G +R+ + NG L ++ +EG YTC A+N G DE +
Sbjct: 2072 WSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMK 2131
Query: 110 GRL-IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
L ++ APR + + L C DP +L N + I S D Y
Sbjct: 2132 VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDM-ISFSIDRY 2190
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G LTI V L D G+Y CV ++ G + +L + P
Sbjct: 2191 TFHA----NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKP 2234
Score = 66.1 bits (154), Expect = 4e-10
Identities = 59/218 (27%), Positives = 90/218 (41%), Gaps = 11/218 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N L L V++ P ++ + + G L C+ PKP W
Sbjct: 2117 YTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKA-GDTAVLDCEVTGDPKPKIFW 2175
Query: 62 K-KDNIVIGAGGKRFITE-NGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
N +I R+ NG+L I ++ D G Y CVA+N G D +L V+ P
Sbjct: 2176 LLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPP 2235
Query: 120 FLEKLPP-----RITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
+ L + TA +S C A+ P + ++ N I ++ Y ++
Sbjct: 2236 LINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDN---IFLTAPYYGSRITV 2292
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G L I NV LSD D+ CV ++ G VQL +
Sbjct: 2293 HKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEV 2330
Score = 52.0 bits (119), Expect = 7e-06
Identities = 40/181 (22%), Positives = 71/181 (39%), Gaps = 10/181 (5%)
Query: 42 GGNVTLKCKPEAAPKPTFTWKKDNIVI-----GAGGKRFITENGNLIIRQLSRDDEGVYT 96
G + L C PKP W+ + + G + NG+L I ++ D GVY
Sbjct: 1956 GDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYL 2015
Query: 97 CVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVVF-LHCNADVDPILDTAYLWN 155
CVA+N+ G D + + P ++ ++ F + C A P+ + ++
Sbjct: 2016 CVARNKMGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLP 2075
Query: 156 H----NGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLR 211
N D S + + G L V +++ GDY C ++ +G+ V L
Sbjct: 2076 DGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLT 2135
Query: 212 I 212
+
Sbjct: 2136 V 2136
Score = 45.6 bits (103), Expect = 6e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 8/112 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C+A+N + + + + +++ P P G L C PKP TW
Sbjct: 2504 YICKAQNSVGHTLITVPVMIVAYPPRITNRPPR-SIVTRTGAAFQLHCVALGVPKPEITW 2562
Query: 62 KK-DNIVIGAG------GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+ D+ ++ G + G L+I+ D G+Y C AKN G+D
Sbjct: 2563 EMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSD 2614
Score = 44.8 bits (101), Expect = 0.001
Identities = 40/168 (23%), Positives = 68/168 (40%), Gaps = 12/168 (7%)
Query: 42 GGNVTLKCKPEAAPKPTFTW------KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVY 95
GG V L C + P P W K + G+ I ++G L ++ D GVY
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVY 549
Query: 96 TCVAKNQYGTDESRGRLIVLR-APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLW 154
C++ N D R+ V+ ++ T + + L C++ P +++
Sbjct: 550 HCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVI 609
Query: 155 NHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
N + + S D K++ ++ G L I V+ D G Y CV + G
Sbjct: 610 PGNNVLYQSSRD----KKV-LNNGTLRILQVTPKDQGYYRCVAANPSG 652
Score = 41.1 bits (92), Expect = 0.012
Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLS-LKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y C + N A + ++ V+ L +++++ + + E + L C P +
Sbjct: 548 VYHCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGE--TLDLPCHSTGIPDASI 605
Query: 60 TW--KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+W +N++ + + + NG L I Q++ D+G Y CVA N G D
Sbjct: 606 SWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSGVD 654
Score = 39.1 bits (87), Expect = 0.050
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 4/104 (3%)
Query: 114 VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ PR + T NS FL C A +P+ + +GL D S N R+
Sbjct: 1644 IFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGL---DLSKRKQNSRV 1700
Query: 174 KI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ G L+I V + D G Y C + G HV L + P
Sbjct: 1701 QVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYP 1744
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 83.4 bits (197), Expect = 2e-15
Identities = 67/219 (30%), Positives = 95/219 (43%), Gaps = 11/219 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + L V+S P + + T S G V LKC+ E P PT TW
Sbjct: 348 YLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHS-GSTVELKCRAEGRPSPTVTW 406
Query: 62 KKDNIVI---GAGGKR--FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
N + + G R +T +G L++ LS D G Y CVA N G D ++ V+
Sbjct: 407 ILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIA 466
Query: 117 APR-FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKI 175
AP LE+ I + L C A P + Y +G +K + N ++ +
Sbjct: 467 APPVILEQRRQVIVGTWGESLKLPCTAKGTP-QPSVYWVLSDGTEVKPLQ--FTNSKLFL 523
Query: 176 -DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
G L I N++ SD G YEC+ S+ G V L +E
Sbjct: 524 FSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTME 562
Score = 69.3 bits (162), Expect = 4e-11
Identities = 50/176 (28%), Positives = 80/176 (45%), Gaps = 8/176 (4%)
Query: 47 LKCKPEAAPKPTFTWKKDNIVIGAGGKRF-----ITENGNLIIRQLSRDDEGVYTCVAKN 101
L C+ P PT W + + ++ + NG L I+++ D G Y C A N
Sbjct: 295 LPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASN 354
Query: 102 QYGTDESRGRL-IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLR 160
+GTD L +V PR LE+ IT S V L C A+ P ++ N
Sbjct: 355 LFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWIL-ANQTV 413
Query: 161 IKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ +SS + +D G L ++N+S+ D G Y+CV + G+ S V++++ P
Sbjct: 414 VSESSQGSRQAVVTVD-GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAP 468
Score = 39.1 bits (87), Expect = 0.050
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 4/104 (3%)
Query: 114 VLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
+ PR + T NS FL C A +P+ + +GL D S N R+
Sbjct: 271 IFEKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGL---DLSKRKQNSRV 327
Query: 174 KI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
++ G L+I V + D G Y C + G HV L + P
Sbjct: 328 QVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYP 371
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 82.6 bits (195), Expect = 4e-15
Identities = 54/239 (22%), Positives = 113/239 (47%), Gaps = 7/239 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+CE + + + ++V+ ++ P+ + + + G +VTL C E P+PT +
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 246
Query: 61 WKKDNIVIGA--GGKRFI--TENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I +++I ++ L I+++ ++DE Y C+A+N+ G ++ L V
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA 306
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS-DLYVNKRIKI 175
P+ + + + ++ V L C A DPI + + + ++ + D ++ R
Sbjct: 307 KPK-ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA 365
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
LT+ ++ +D G+Y C + IG+ S + L ++ P G V + + + V +
Sbjct: 366 RVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 424
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 16/224 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRV-LSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y+C + S S A + V + K FK P E EG + + C ++ PT
Sbjct: 93 IYKCVVTGE-DGSESEATVNVKIFQKLMFKNAPTPQEF--REGEDAVIVCDVVSSLPPTI 149
Query: 60 TWK-KDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAK-NQYGTDESRGRLIVLR 116
WK K VI RFI + N + IR + + DEG Y C + G + +++
Sbjct: 150 IWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN 209
Query: 117 APRFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD--LYVNKR 172
P ++ + TA + V L C+A+ P + W +G +I+ D Y+
Sbjct: 210 VPPTIQARQNIVNATANLGQSVTLVCDAEGFP--EPTMSWTKDGEQIEQEEDDEKYI--- 264
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D +LTI V +D +Y C+ ++ G + + L++ P
Sbjct: 265 FSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 58.4 bits (135), Expect = 8e-08
Identities = 88/372 (23%), Positives = 138/372 (37%), Gaps = 41/372 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N+ ++ L+V + KP +E +T VTL C+ P P+ TW
Sbjct: 285 YICIAENKAGEQDATIHLKVFA-KPKITY--VENQTAMELEEQVTLTCEASGDPIPSITW 341
Query: 62 KKDNIVIGAGGKRFITENGNLIIRQLSR-----------DDEGVYTCVAKNQYGTDESRG 110
+ I + K T +G++++R +R D G Y C A N G D
Sbjct: 342 RTSTRNISSEEK---TLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSM 398
Query: 111 RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVN 170
L V AP+ + P + + V + C P W +G + S+ +
Sbjct: 399 YLEVQYAPKL--QGPVAVYTWEGNQVNITCEVFAYP--SATISWFRDGQLLPSSNYSNIK 454
Query: 171 KRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRS 230
L + S +D G+Y C + IG+ S L P P Q+ S
Sbjct: 455 IYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYS-S 513
Query: 231 SVTLEWTDSNSNGR-PITGY----MLTGRTHWNSTWYVISE-NIPNVMEVDRYNGRKRAT 284
+ +++ + + G PI Y G W+S WY E ++ ++ +
Sbjct: 514 TAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTI---------- 563
Query: 285 VSTTLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTIT 344
L P Y R+ A+N G G+ SA S +F T PA+ S T
Sbjct: 564 --VGLKPETTYAVRLAALNGKGLGEISAAS-EFKTQPVHSPPPPASASSSTPVPLSPPDT 620
Query: 345 WTPLPTSLQNGP 356
PLP P
Sbjct: 621 TWPLPALATTEP 632
Score = 36.3 bits (80), Expect = 0.35
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 79 NGNLIIRQLSRDDEGVYTCVAKNQYGTD-ESRGRLIVLRAPRFLEKLPPRITAQVNSVVF 137
+ L I + DD G+Y CV + G++ E+ + + + F P+ + V
Sbjct: 78 SSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI 137
Query: 138 LHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV 197
+ DV L +W H G + D+ + I + L I + +D G Y C
Sbjct: 138 V---CDVVSSLPPTIIWKHKGRDVILKKDV---RFIVLSNNYLQIRGIKKTDEGTYRCEG 191
Query: 198 K-SAIGRIS-SHVQLRIEGPP 216
+ A G I+ +Q+ + PP
Sbjct: 192 RILARGEINFKDIQVIVNVPP 212
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 82.6 bits (195), Expect = 4e-15
Identities = 54/239 (22%), Positives = 113/239 (47%), Gaps = 7/239 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+CE + + + ++V+ ++ P+ + + + G +VTL C E P+PT +
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMS 246
Query: 61 WKKDNIVIGA--GGKRFI--TENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I +++I ++ L I+++ ++DE Y C+A+N+ G ++ L V
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA 306
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS-DLYVNKRIKI 175
P+ + + + ++ V L C A DPI + + + ++ + D ++ R
Sbjct: 307 KPK-ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA 365
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
LT+ ++ +D G+Y C + IG+ S + L ++ P G V + + + V +
Sbjct: 366 RVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 424
Score = 58.4 bits (135), Expect = 8e-08
Identities = 57/224 (25%), Positives = 95/224 (42%), Gaps = 16/224 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRV-LSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y+C + S S A + V + K FK P E EG + + C ++ PT
Sbjct: 93 IYKCVVTGE-DGSESEATVNVKIFQKLMFKNAPTPQEF--REGEDAVIVCDVVSSLPPTI 149
Query: 60 TWK-KDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAK-NQYGTDESRGRLIVLR 116
WK K VI RFI + N + IR + + DEG Y C + G + +++
Sbjct: 150 IWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN 209
Query: 117 APRFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD--LYVNKR 172
P + + TA + V L C+A+ P + W +G +I+ D Y+
Sbjct: 210 VPPTIRARQNIVNATANLGQSVTLVCDAERFP--EPTMSWTKDGEQIEQEEDDEKYI--- 264
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D +LTI V +D +Y C+ ++ G + + L++ P
Sbjct: 265 FSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 40.3 bits (90), Expect = 0.022
Identities = 68/276 (24%), Positives = 112/276 (40%), Gaps = 28/276 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + S L V P + P+ + T+ EG V + C+ A P T +W
Sbjct: 383 YICTASNTIGQDSQSMYLEV-QYAPKLQG-PVAVYTW--EGNQVNITCEVFAYPSATISW 438
Query: 62 KKDNIVIGAGG----KRFITENGN-LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+D ++ + K + T + + L + S +D G Y C A N+ G + L+
Sbjct: 439 FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQAD 498
Query: 117 APR--FLEKLPP-RITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKR 172
P ++++ P TAQV F A PIL W G + S Y K
Sbjct: 499 TPSSPSIDQVEPYSSTAQVQ---FDEPEATGGVPILKYKAEWRAVGEEVWHSK-WYDAKE 554
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKS----AIGRISSHVQLR---IEGPPGPPGGVQIL 225
++ G +TI V L Y + + +G IS+ + + ++G P P +
Sbjct: 555 ASME-GIVTI--VGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQM 611
Query: 226 GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
G +S+ + + G PI Y++ R +S W
Sbjct: 612 GEDGNSIKVNLIKQDDGGSPIRHYLVRYRA-LSSEW 646
Score = 36.3 bits (80), Expect = 0.35
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 79 NGNLIIRQLSRDDEGVYTCVAKNQYGTD-ESRGRLIVLRAPRFLEKLPPRITAQVNSVVF 137
+ L I + DD G+Y CV + G++ E+ + + + F P+ + V
Sbjct: 78 SSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI 137
Query: 138 LHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV 197
+ DV L +W H G + D+ + I + L I + +D G Y C
Sbjct: 138 V---CDVVSSLPPTIIWKHKGRDVILKKDV---RFIVLSNNYLQIRGIKKTDEGTYRCEG 191
Query: 198 K-SAIGRIS-SHVQLRIEGPP 216
+ A G I+ +Q+ + PP
Sbjct: 192 RILARGEINFKDIQVIVNVPP 212
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 82.6 bits (195), Expect = 4e-15
Identities = 54/239 (22%), Positives = 113/239 (47%), Gaps = 7/239 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+CE + + + ++V+ ++ P+ + + + G +VTL C E P+PT +
Sbjct: 187 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 246
Query: 61 WKKDNIVIGA--GGKRFI--TENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I +++I ++ L I+++ ++DE Y C+A+N+ G ++ L V
Sbjct: 247 WTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA 306
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS-DLYVNKRIKI 175
P+ + + + ++ V L C A DPI + + + ++ + D ++ R
Sbjct: 307 KPK-ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA 365
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
LT+ ++ +D G+Y C + IG+ S + L ++ P G V + + + V +
Sbjct: 366 RVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 424
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 16/224 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRV-LSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y+C + S S A + V + K FK P E EG + + C ++ PT
Sbjct: 93 IYKCVVTGE-DGSESEATVNVKIFQKLMFKNAPTPQEF--REGEDAVIVCDVVSSLPPTI 149
Query: 60 TWK-KDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAK-NQYGTDESRGRLIVLR 116
WK K VI RFI + N + IR + + DEG Y C + G + +++
Sbjct: 150 IWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN 209
Query: 117 APRFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD--LYVNKR 172
P ++ + TA + V L C+A+ P + W +G +I+ D Y+
Sbjct: 210 VPPTIQARQNIVNATANLGQSVTLVCDAEGFP--EPTMSWTKDGEQIEQEEDDEKYI--- 264
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D +LTI V +D +Y C+ ++ G + + L++ P
Sbjct: 265 FSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 308
Score = 40.3 bits (90), Expect = 0.022
Identities = 68/276 (24%), Positives = 112/276 (40%), Gaps = 28/276 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + S L V P + P+ + T+ EG V + C+ A P T +W
Sbjct: 383 YICTASNTIGQDSQSMYLEV-QYAPKLQG-PVAVYTW--EGNQVNITCEVFAYPSATISW 438
Query: 62 KKDNIVIGAGG----KRFITENGN-LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+D ++ + K + T + + L + S +D G Y C A N+ G + L+
Sbjct: 439 FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQAD 498
Query: 117 APR--FLEKLPP-RITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKR 172
P ++++ P TAQV F A PIL W G + S Y K
Sbjct: 499 TPSSPSIDQVEPYSSTAQVQ---FDEPEATGGVPILKYKAEWRAVGEEVWHSK-WYDAKE 554
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKS----AIGRISSHVQLR---IEGPPGPPGGVQIL 225
++ G +TI V L Y + + +G IS+ + + ++G P P +
Sbjct: 555 ASME-GIVTI--VGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQM 611
Query: 226 GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
G +S+ + + G PI Y++ R +S W
Sbjct: 612 GEDGNSIKVNLIKQDDGGSPIRHYLVRYRA-LSSEW 646
Score = 36.3 bits (80), Expect = 0.35
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 79 NGNLIIRQLSRDDEGVYTCVAKNQYGTD-ESRGRLIVLRAPRFLEKLPPRITAQVNSVVF 137
+ L I + DD G+Y CV + G++ E+ + + + F P+ + V
Sbjct: 78 SSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI 137
Query: 138 LHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV 197
+ DV L +W H G + D+ + I + L I + +D G Y C
Sbjct: 138 V---CDVVSSLPPTIIWKHKGRDVILKKDV---RFIVLSNNYLQIRGIKKTDEGTYRCEG 191
Query: 198 K-SAIGRIS-SHVQLRIEGPP 216
+ A G I+ +Q+ + PP
Sbjct: 192 RILARGEINFKDIQVIVNVPP 212
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 82.6 bits (195), Expect = 4e-15
Identities = 59/220 (26%), Positives = 88/220 (40%), Gaps = 16/220 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + + +L V+ + P HP +EG +L C P PT TW
Sbjct: 216 YSCVATNTAGSQHRDVEL-VVQVPPRI--HPTATHHITNEGVPASLPCVASGVPAPTITW 272
Query: 62 KKDNIVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRF 120
K+ + + G + +++ G L+I Q S D G Y C A N G RL V PR
Sbjct: 273 TKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRI 332
Query: 121 ------LEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
+P ++TA+ V L C A P W + + ++ Y
Sbjct: 333 HMNGSRNADVPLQVTAKAGEEVTLDCEAKGSP--PPLVTWTKDSRPVPPITNRYG----L 386
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEG 214
+ G L + V + D G YEC + G S L ++G
Sbjct: 387 LPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQG 426
Score = 62.1 bits (144), Expect = 6e-09
Identities = 58/223 (26%), Positives = 92/223 (41%), Gaps = 17/223 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N+L + + QL V P + P ++ G + L C+ P PT TW
Sbjct: 26 YTCRAVNELGDASAEIQLAV-GHAPQLTELPRDVTV--ELGRSALLACRATGRPPPTVTW 82
Query: 62 KKDN-----IVIGAG-GKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
++ + + +GAG G R ++G L ++ +D+ Y C A+N +G ++ RLIV
Sbjct: 83 RRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 142
Query: 115 L-RAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
AP + P + V L C L + W +G + S I
Sbjct: 143 TGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH-WLKDGRPLPPGS----RHSI 197
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ D G L + G Y CV + G V+L ++ PP
Sbjct: 198 RAD-GSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPP 239
Score = 54.4 bits (125), Expect = 1e-06
Identities = 57/217 (26%), Positives = 82/217 (37%), Gaps = 11/217 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLS-LKPSFKKHPLELETYGSEGGNVTLKCKPEAA-PKPTF 59
Y CEA+N + A+L V P + EG V+L C A P P
Sbjct: 123 YVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVL--EGQPVSLPCIVLAGRPLPER 180
Query: 60 TWKKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPR 119
W KD + G + I +G+L + + ++ G Y+CVA N G+ L+V PR
Sbjct: 181 HWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPR 240
Query: 120 FLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGE 179
IT + L C A P + N L + V+K G
Sbjct: 241 IHPTATHHITNE-GVPASLPCVASGVPAPTITWTKETNALTSR-GPHYNVSKE-----GT 293
Query: 180 LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I S D G Y C + +G S ++L + P
Sbjct: 294 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKP 330
Score = 47.6 bits (108), Expect = 1e-04
Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 11/147 (7%)
Query: 77 TENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAPRFLEKLPPRITAQVNSVV 136
+ +G L I D G YTC A N+ G + +L V AP+ L +LP +T ++
Sbjct: 8 SSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQ-LTELPRDVTVELGRSA 66
Query: 137 FLHCNADVDPILDTAYLWNHN-----GLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVG 191
L C A P W GLR+ ++ + D G L +V+ D
Sbjct: 67 LLACRATGRP--PPTVTWRRGDGQPLGLRLGAGRG---SRSRQPDSGVLFFESVAPEDQA 121
Query: 192 DYECVVKSAIGRISSHVQLRIEGPPGP 218
Y C ++ G++ + +L + G P
Sbjct: 122 PYVCEARNVFGKVQAEARLIVTGHAPP 148
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 82.6 bits (195), Expect = 4e-15
Identities = 54/239 (22%), Positives = 113/239 (47%), Gaps = 7/239 (2%)
Query: 2 YQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+CE + + + ++V+ ++ P+ + + + G +VTL C E P+PT +
Sbjct: 268 YRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMS 327
Query: 61 WKKDNIVIGA--GGKRFI--TENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
W KD I +++I ++ L I+++ ++DE Y C+A+N+ G ++ L V
Sbjct: 328 WTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFA 387
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSS-DLYVNKRIKI 175
P+ + + + ++ V L C A DPI + + + ++ + D ++ R
Sbjct: 388 KPK-ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHA 446
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQRSSVTL 234
LT+ ++ +D G+Y C + IG+ S + L ++ P G V + + + V +
Sbjct: 447 RVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNI 505
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/224 (25%), Positives = 96/224 (42%), Gaps = 16/224 (7%)
Query: 1 MYQCEAKNQLKASYSSAQLRV-LSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y+C + S S A + V + K FK P E EG + + C ++ PT
Sbjct: 174 IYKCVVTGE-DGSESEATVNVKIFQKLMFKNAPTPQEF--REGEDAVIVCDVVSSLPPTI 230
Query: 60 TWK-KDNIVIGAGGKRFITENGNLI-IRQLSRDDEGVYTCVAK-NQYGTDESRGRLIVLR 116
WK K VI RFI + N + IR + + DEG Y C + G + +++
Sbjct: 231 IWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN 290
Query: 117 APRFLEKLPPRI--TAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSD--LYVNKR 172
P ++ + TA + V L C+A+ P + W +G +I+ D Y+
Sbjct: 291 VPPTIQARQNIVNATANLGQSVTLVCDAEGFP--EPTMSWTKDGEQIEQEEDDEKYI--- 345
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
D +LTI V +D +Y C+ ++ G + + L++ P
Sbjct: 346 FSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKP 389
Score = 40.3 bits (90), Expect = 0.022
Identities = 68/276 (24%), Positives = 112/276 (40%), Gaps = 28/276 (10%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A N + S L V P + P+ + T+ EG V + C+ A P T +W
Sbjct: 464 YICTASNTIGQDSQSMYLEV-QYAPKLQG-PVAVYTW--EGNQVNITCEVFAYPSATISW 519
Query: 62 KKDNIVIGAGG----KRFITENGN-LIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR 116
+D ++ + K + T + + L + S +D G Y C A N+ G + L+
Sbjct: 520 FRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQAD 579
Query: 117 APR--FLEKLPP-RITAQVNSVVFLHCNADVD-PILDTAYLWNHNGLRIKDSSDLYVNKR 172
P ++++ P TAQV F A PIL W G + S Y K
Sbjct: 580 TPSSPSIDQVEPYSSTAQVQ---FDEPEATGGVPILKYKAEWRAVGEEVWHSK-WYDAKE 635
Query: 173 IKIDGGELTIYNVSLSDVGDYECVVKS----AIGRISSHVQLR---IEGPPGPPGGVQIL 225
++ G +TI V L Y + + +G IS+ + + ++G P P +
Sbjct: 636 ASME-GIVTI--VGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQM 692
Query: 226 GIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTW 261
G +S+ + + G PI Y++ R +S W
Sbjct: 693 GEDGNSIKVNLIKQDDGGSPIRHYLVRYRA-LSSEW 727
Score = 36.3 bits (80), Expect = 0.35
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 79 NGNLIIRQLSRDDEGVYTCVAKNQYGTD-ESRGRLIVLRAPRFLEKLPPRITAQVNSVVF 137
+ L I + DD G+Y CV + G++ E+ + + + F P+ + V
Sbjct: 159 SSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVI 218
Query: 138 LHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVV 197
+ DV L +W H G + D+ + I + L I + +D G Y C
Sbjct: 219 V---CDVVSSLPPTIIWKHKGRDVILKKDV---RFIVLSNNYLQIRGIKKTDEGTYRCEG 272
Query: 198 K-SAIGRIS-SHVQLRIEGPP 216
+ A G I+ +Q+ + PP
Sbjct: 273 RILARGEINFKDIQVIVNVPP 293
>AK001694-1|BAA91841.1| 574|Homo sapiens protein ( Homo sapiens
cDNA FLJ10832 fis, clone NT2RP4001150, weakly similar to
NG-CAM RELATED CELL ADHESION MOLECULE PRECURSOR. ).
Length = 574
Score = 81.4 bits (192), Expect = 9e-15
Identities = 86/328 (26%), Positives = 133/328 (40%), Gaps = 21/328 (6%)
Query: 303 NILGPGQPSAPSPQFSTSGDKPYEAPANVSGGGGKTGDLTITWTPLPTSLQNGPGIHYKI 362
N +G G PS+P + P AP NV G L +TW P P QNG YKI
Sbjct: 5 NAVGEG-PSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKI 63
Query: 363 -FWR-RNGSEVEFQSLLLKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVT 420
FW + G+ E L + V + + YT Y V V AFN G GP S
Sbjct: 64 YFWEAQRGNLTERVKTLFPAENS-----VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQ 118
Query: 421 IYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKY---WKQENKE 477
+ + P AP V +T++NV+W ++ + G L G+RL Y +
Sbjct: 119 GQTQQAAPS-APSSVKFSELTTTSVNVSW----EAPQFPNGILEGYRLVYEPCSPVDGVS 173
Query: 478 EECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPAS 537
+ + + W + L Y ++ A + GPE E + + PP
Sbjct: 174 KIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGEGAPGPP-G 231
Query: 538 VNVWAHDPTTLRVVWRYVQPTNEEEPLLGYKVRLWELDQDMSTANDTIVPIEHKLEAYIS 597
V + + + + W P + P+ Y + D+ + +P E +
Sbjct: 232 VPIIVRYSSAIAIHWSSGDP--GKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSM 289
Query: 598 NII-PGKSYNLRVLAYSNGGDGRMSSPT 624
+I+ PG SY+ RV+A ++ G G SSP+
Sbjct: 290 DILKPGVSYDFRVIAVNDYGFGTPSSPS 317
Score = 68.9 bits (161), Expect = 5e-11
Identities = 47/157 (29%), Positives = 72/157 (45%), Gaps = 5/157 (3%)
Query: 404 VQAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKL 463
+ +N +G GP S ++ E +P AP+ V +T L+VTW P + G +
Sbjct: 1 MSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEP--PPLDSQNGDI 58
Query: 464 IGHRLKYWK-QENKEEECIYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERY 522
G+++ +W+ Q E + L N + L T Y V V AFN+AG+GP S
Sbjct: 59 QGYKIYFWEAQRGNLTERVKTLF-PAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPT 117
Query: 523 LERTFRKAPQKPPASVNVWAHDPTTLRVVWRYVQPTN 559
+T + AP P+SV T++ V W Q N
Sbjct: 118 QGQTQQAAP-SAPSSVKFSELTTTSVNVSWEAPQFPN 153
Score = 61.7 bits (143), Expect = 8e-09
Identities = 38/114 (33%), Positives = 56/114 (49%), Gaps = 10/114 (8%)
Query: 213 EGPPGPPGGVQILGIQRSSVTLEWTDSNSNGRPITGYMLTGRTHWNSTWYVISENIPNVM 272
EG PGPPG V I+ S++ + W+ + PIT Y++ R W ++ ++IP
Sbjct: 224 EGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPK-- 280
Query: 273 EVDRYNGRKRATVSTTLL-PWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPY 325
EV Y T S +L P Y+FR+ A+N G G PS+PS P+
Sbjct: 281 EVSSY------TFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPF 328
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 81.4 bits (192), Expect = 9e-15
Identities = 66/227 (29%), Positives = 107/227 (47%), Gaps = 18/227 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y C A+N++ Y ++ V+ +KP+ +H E + GG++ + C P P +W
Sbjct: 2219 YLCVARNKVGDDYVVLKVDVV-MKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISW 2277
Query: 62 K-KDNIVIGA-------GG--KRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
D ++ + GG KR++ NG L ++ +EG YTC A+NQ G DE R
Sbjct: 2278 SLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRV 2337
Query: 111 RLIVLRAPRFL-EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYV 169
R+ V+ AP + K + VV + C A +P+ +L N + I SS+ Y
Sbjct: 2338 RVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKV-IPTSSEKY- 2395
Query: 170 NKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+I D G L I SD G+Y C+V+++ G V + + P
Sbjct: 2396 --QIYQD-GTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQP 2439
Score = 81.0 bits (191), Expect = 1e-14
Identities = 67/222 (30%), Positives = 101/222 (45%), Gaps = 15/222 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C A N A + +L V +L P + LE + G ++ + C +AAP P+
Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISL-PPGLSIHIHCTAKAAPLPSVR 2080
Query: 61 WKK-DNIVIGAG----GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W D I G F+ NG L IR L+ D G Y CVA N G+ +L V
Sbjct: 2081 WVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQ 2140
Query: 116 RA---PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKR 172
RA R P R + + L C+A DP LW R+ D+ + + R
Sbjct: 2141 RAAANARITGTSPRRTDVRYGGTLKLDCSASGDPW--PRILWRLPSKRMIDALFSF-DSR 2197
Query: 173 IKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
IK+ G L + +V+ D GDY CV ++ +G +V L+++
Sbjct: 2198 IKVFANGTLVVKSVTDKDAGDYLCVARNKVG--DDYVVLKVD 2237
Score = 74.1 bits (174), Expect = 1e-12
Identities = 61/220 (27%), Positives = 92/220 (41%), Gaps = 13/220 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSF-KKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y C A N L V +P H ++ Y G + ++C + P P +
Sbjct: 1926 YMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVY--LGDTIAMECLAKGTPAPQIS 1983
Query: 61 W-----KKDNIVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W + V + + EN L I++ S D GVY CVA N G D RL V
Sbjct: 1984 WIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVA 2043
Query: 116 RAPRFL--EKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRI 173
P + EKL I+ + +HC A P+ ++ +G +I+ S L+ N +
Sbjct: 2044 ALPPVIHQEKL-ENISLPPGLSIHIHCTAKAAPLPSVRWVLG-DGTQIRPSQFLHGNLFV 2101
Query: 174 KIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIE 213
G L I N++ D G YECV + +G VQL ++
Sbjct: 2102 -FPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQ 2140
Score = 73.3 bits (172), Expect = 3e-12
Identities = 61/217 (28%), Positives = 97/217 (44%), Gaps = 9/217 (4%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
Y+C A+N + L+V LKP K L + G + L C P A + F+W
Sbjct: 2614 YRCVARNAAGHTERLVSLKV-GLKPEANKQYHNLVSI-INGETLKLPCTPPGAGQGRFSW 2671
Query: 62 KKDNIVIGAG----GKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLR- 116
N + G G+ + +NG L +R+ S D G Y C + +YG + +IV+
Sbjct: 2672 TLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAY 2731
Query: 117 APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAY-LWNHNGLRIKDSSDLYVNKRIKI 175
PR + P I + + V L+C A P D + L + + L+ + LY N R
Sbjct: 2732 PPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGN-RFLH 2790
Query: 176 DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
G LTI + + D G Y+C+ K+ +G S + +
Sbjct: 2791 PQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
Score = 67.7 bits (158), Expect = 1e-10
Identities = 58/221 (26%), Positives = 91/221 (41%), Gaps = 13/221 (5%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETY---GSEGGNVTLKCKPEAAPKPT 58
Y C +N + + V P +P + T + G + CK E P P
Sbjct: 2416 YTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPR 2475
Query: 59 FTWK-KDNIVIGA---GGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIV 114
W + +V+ A G + + NG+L IR L + D C+A+N+ G +L V
Sbjct: 2476 VLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTV 2535
Query: 115 LRA---PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNK 171
L P F + + +ITA + L+C+A P ++ NG ++ L
Sbjct: 2536 LEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLP-NGTDLQSGQQLQRFY 2594
Query: 172 RIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
K DG L I +S D G Y CV ++A G V L++
Sbjct: 2595 H-KADG-MLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/175 (27%), Positives = 77/175 (44%), Gaps = 10/175 (5%)
Query: 49 CKPEAAPKPTFTWKKDN----IVIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAKNQY 103
C+ PKP TW K + + +RF + +NG L+IR++ D G Y C A N +
Sbjct: 1875 CEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDRGQYMCTASNLH 1934
Query: 104 GTDESRGRL-IVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIK 162
G D L + ++ P+ L +T + + + C A P + W R+
Sbjct: 1935 GLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQIS--WIFPDRRVW 1992
Query: 163 DSSDLYVNKRIKI-DGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
+ V RI + + L+I S SD G Y+CV +A G S ++L + P
Sbjct: 1993 QTVS-PVESRITLHENRTLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALP 2046
Score = 52.0 bits (119), Expect = 7e-06
Identities = 51/240 (21%), Positives = 94/240 (39%), Gaps = 15/240 (6%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFK-KHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
Y+C A N + ++ + QL V + + T GG + L C P P
Sbjct: 2120 YECVAANLVGSARRTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRIL 2179
Query: 61 WKKDN-----IVIGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVL 115
W+ + + + + NG L+++ ++ D G Y CVA+N+ G D ++ V+
Sbjct: 2180 WRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVV 2239
Query: 116 RAPRFLE-------KLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLY 168
P +E K+ +V+ V N ++ L L N D S
Sbjct: 2240 MKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSL--VNSFMQSDDSGGR 2297
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
+ + + G L V + + GDY C ++ +G+ V++++ P L +Q
Sbjct: 2298 TKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQ 2357
Score = 48.4 bits (110), Expect = 8e-05
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGG-NVTLKCKPEAAPKPTF 59
+YQC A Q++ RVL PS + + T G G +VTL C A P+
Sbjct: 552 LYQCIA--QVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHL 609
Query: 60 TWKKDN--IV--IGAGGKRFITENGNLIIRQLSRDDEGVYTCVAKNQYGTD 106
+W N I+ + ++ NG L I ++ D G Y CVA NQ G D
Sbjct: 610 SWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQGAD 660
Score = 46.4 bits (105), Expect = 3e-04
Identities = 45/169 (26%), Positives = 73/169 (43%), Gaps = 10/169 (5%)
Query: 41 EGGNVTLKCKPEAAPKPTFTWK-KDNIVIGA-----GGKRFITENGNLIIRQLSRDDEGV 94
EGG L C +A+ P+ W D ++ A K I +G L I+ + D G+
Sbjct: 493 EGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGL 552
Query: 95 YTCVAKNQYGTDESRGRLIVLR-APRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYL 153
Y C+A+ + D R++V + + EK I V L CNA P +++
Sbjct: 553 YQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWI 612
Query: 154 WNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIG 202
+ + I D ++ + + G L+I V +SD G Y CV + G
Sbjct: 613 LPNRRI-INDLAN--TSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 80.6 bits (190), Expect = 2e-14
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 9/222 (4%)
Query: 1 MYQCEAKNQLKASYSSAQLRVL-SLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTF 59
+Y+CE + + + + V+ ++ P+ G +T C+ +P+P
Sbjct: 183 IYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAI 242
Query: 60 TWKKDNIVIGAGGKRFIT-ENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRAP 118
+W ++ +I K + N L +R + D G Y C A N+ G DE + L V P
Sbjct: 243 SWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQP 302
Query: 119 RFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG- 177
++ T N V L C+A+ +PI + + +G + D ++ RI++ G
Sbjct: 303 HIIQL--KNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTE-GDKSLDGRIEVKGQ 359
Query: 178 ---GELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
L I +V LSD G Y+C S IG + L IE P
Sbjct: 360 HGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAP 401
Score = 76.2 bits (179), Expect = 4e-13
Identities = 114/461 (24%), Positives = 188/461 (40%), Gaps = 55/461 (11%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGS-EGGNVTLKCKPEAAPKPTFT 60
Y C A N+ A L+V ++P H ++L+ + E G VTL C E P P T
Sbjct: 279 YVCRATNKAGEDEKQAFLQVF-VQP----HIIQLKNETTYENGQVTLVCDAEGEPIPEIT 333
Query: 61 WKK--DNIVIGAGGKRF---ITENG-----NLIIRQLSRDDEGVYTCVAKNQYGTDESRG 110
WK+ D G K I G +L I+ + D G Y C A ++ G +
Sbjct: 334 WKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSM 393
Query: 111 RLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDL--Y 168
L + AP+F+ + + N + + C+ +P + + L K++++L Y
Sbjct: 394 YLDIEYAPKFISNQTIYYSWEGNPIN-ISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTY 452
Query: 169 VNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPPGPPGGVQILGIQ 228
R I L I S +D G Y C + IG L + P P GV+I+ +
Sbjct: 453 STGRKMI----LEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIELS 508
Query: 229 RSSVTLEWTDSNSNGR-PITGYMLTGRTHWNSTWYVISENIPNVMEVDRYNGRKRATVST 287
+++ + + +S+G PI Y + + + W ++ R +G + V
Sbjct: 509 QTTAKVSFNKPDSHGGVPIHHYQVDVKEVASEIWKIV-----------RSHGVQTMVVLN 557
Query: 288 TLLPWAIYEFRIQAINILGPGQPSAPSPQFSTSGDKPYEAPANVSG--GGGKTGDLTITW 345
L P YE R+ A+N G GQ + + +P ++ G GK+ L+IT
Sbjct: 558 NLEPNTTYEIRVAAVN--GKGQGDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKLSIT- 614
Query: 346 TPLPTSLQNGPGIHYKIFWRRNGSEVEFQSLLLKKYGNIGTYVV-HISSTYFYTPYDVKV 404
P + Y + +R + E Q L K GN ++ H+ T Y+V++
Sbjct: 615 ---KQDDGGAPILEYIVKYR--SKDKEDQWLEKKVQGNKDHIILEHLQWT---MGYEVQI 666
Query: 405 QAFNDIGPGPESEVVTIYSAEDMPQVAPQLVSARSFNSTAL 445
A N +G SE T+Y P+ P ++ FN L
Sbjct: 667 TAANRLG---YSE-PTVYEFSMPPK--PNIIKDTLFNGLGL 701
Score = 59.3 bits (137), Expect = 4e-08
Identities = 50/218 (22%), Positives = 97/218 (44%), Gaps = 15/218 (6%)
Query: 1 MYQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFT 60
+Y+C+A + + + + + K +F++ E +G + + C+ ++P P +
Sbjct: 90 IYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQEF--KQGEDAEVVCRVSSSPAPAVS 147
Query: 61 WKKDNI-VIGAGGKRF-ITENGNLIIRQLSRDDEGVYTCVAK-NQYGTDESRGRLIVLRA 117
W N V RF + N NL I +++ DEG+Y C + G + R ++++
Sbjct: 148 WLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVNV 207
Query: 118 PRFLEKLPPR---ITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIK 174
P + +P + TA+ + C A P + A W NG ++ + ++ Y+ +K
Sbjct: 208 PPAI-SMPQKSFNATAERGEEMTFSCRASGSP--EPAISWFRNG-KLIEENEKYI---LK 260
Query: 175 IDGGELTIYNVSLSDVGDYECVVKSAIGRISSHVQLRI 212
ELT+ N+ SD G Y C + G L++
Sbjct: 261 GSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQV 298
Score = 32.3 bits (70), Expect = 5.7
Identities = 39/176 (22%), Positives = 70/176 (39%), Gaps = 10/176 (5%)
Query: 362 IFWRRNGSEVEFQSLL-LKKYGNIGTYVVHISSTYFYTPYDVKVQAFNDIGPGPESEVVT 420
I WRR+ + ++ LK Y ++ I+ T A N IG + ++
Sbjct: 432 IHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIGTRFQEYILA 491
Query: 421 IYSAEDMPQVAPQLVSARSFNSTALNVTWNPIDQSRERLRGKLIGHRLKYWKQENKEEEC 480
+ D+P +P V + T V++N D G + H + +E E
Sbjct: 492 L---ADVPS-SPYGVKIIELSQTTAKVSFNKPDS-----HGGVPIHHYQVDVKEVASEIW 542
Query: 481 IYYLSRTTRNWALIVGLQPDTYYYVKVMAFNSAGEGPESERYLERTFRKAPQKPPA 536
S + ++ L+P+T Y ++V A N G+G S+ + +T PP+
Sbjct: 543 KIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREPSPPS 598
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 80.2 bits (189), Expect = 2e-14
Identities = 65/221 (29%), Positives = 93/221 (42%), Gaps = 17/221 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +SYS +++ PSF K P++L G L+C P P W
Sbjct: 579 YQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRA--GAMARLECAAVGHPAPQIAW 636
Query: 62 KKDNIV-IGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+KD A +R + E+ I + +D GVY+C A+N G+ + L VL
Sbjct: 637 QKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLET 696
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P FL L R + + V L C A P W KD S L V +R
Sbjct: 697 PSFLRPLLDRTVTKGETAV-LQCIAGGSP--PPKLNWT------KDDSPLVVTERHFFAA 747
Query: 178 GE--LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I + +SD G Y C + + +G +V+L + P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 52.4 bits (120), Expect = 5e-06
Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 41 EGGNVTLKCKP-EAAPKP-TFTWKKDNIVIG-----------AGGKRFITENGNLIIRQL 87
+G N++ C ++ P TF WKKDN ++ A G + L +R++
Sbjct: 512 KGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREV 571
Query: 88 SRDDEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDP 146
EG Y CV N +G+ S + +L V P F K P +T + ++ L C A P
Sbjct: 572 EFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSF-TKTPMDLTIRAGAMARLECAAVGHP 630
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
A W +G + + + I +V + D+G Y C +++ G IS+
Sbjct: 631 APQIA--WQKDG-GTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISA 687
Query: 207 HVQLRIEGPP 216
+ L + P
Sbjct: 688 NATLTVLETP 697
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 80.2 bits (189), Expect = 2e-14
Identities = 65/221 (29%), Positives = 93/221 (42%), Gaps = 17/221 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +SYS +++ PSF K P++L G L+C P P W
Sbjct: 579 YQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRA--GAMARLECAAVGHPAPQIAW 636
Query: 62 KKDNIV-IGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+KD A +R + E+ I + +D GVY+C A+N G+ + L VL
Sbjct: 637 QKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLET 696
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P FL L R + + V L C A P W KD S L V +R
Sbjct: 697 PSFLRPLLDRTVTKGETAV-LQCIAGGSP--PPKLNWT------KDDSPLVVTERHFFAA 747
Query: 178 GE--LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I + +SD G Y C + + +G +V+L + P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 52.4 bits (120), Expect = 5e-06
Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 41 EGGNVTLKCKP-EAAPKP-TFTWKKDNIVIG-----------AGGKRFITENGNLIIRQL 87
+G N++ C ++ P TF WKKDN ++ A G + L +R++
Sbjct: 512 KGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREV 571
Query: 88 SRDDEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDP 146
EG Y CV N +G+ S + +L V P F K P +T + ++ L C A P
Sbjct: 572 EFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSF-TKTPMDLTIRAGAMARLECAAVGHP 630
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
A W +G + + + I +V + D+G Y C +++ G IS+
Sbjct: 631 APQIA--WQKDG-GTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISA 687
Query: 207 HVQLRIEGPP 216
+ L + P
Sbjct: 688 NATLTVLETP 697
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 80.2 bits (189), Expect = 2e-14
Identities = 65/221 (29%), Positives = 93/221 (42%), Gaps = 17/221 (7%)
Query: 2 YQCEAKNQLKASYSSAQLRVLSLKPSFKKHPLELETYGSEGGNVTLKCKPEAAPKPTFTW 61
YQC N +SYS +++ PSF K P++L G L+C P P W
Sbjct: 579 YQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRA--GAMARLECAAVGHPAPQIAW 636
Query: 62 KKDNIV-IGAGGKR---FITENGNLIIRQLSRDDEGVYTCVAKNQYGTDESRGRLIVLRA 117
+KD A +R + E+ I + +D GVY+C A+N G+ + L VL
Sbjct: 637 QKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLET 696
Query: 118 PRFLEKLPPRITAQVNSVVFLHCNADVDPILDTAYLWNHNGLRIKDSSDLYVNKRIKIDG 177
P FL L R + + V L C A P W KD S L V +R
Sbjct: 697 PSFLRPLLDRTVTKGETAV-LQCIAGGSP--PPKLNWT------KDDSPLVVTERHFFAA 747
Query: 178 GE--LTIYNVSLSDVGDYECVVKSAIGRISSHVQLRIEGPP 216
G L I + +SD G Y C + + +G +V+L + P
Sbjct: 748 GNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP 788
Score = 52.4 bits (120), Expect = 5e-06
Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 18/190 (9%)
Query: 41 EGGNVTLKCKP-EAAPKP-TFTWKKDNIVIG-----------AGGKRFITENGNLIIRQL 87
+G N++ C ++ P TF WKKDN ++ A G + L +R++
Sbjct: 512 KGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREV 571
Query: 88 SRDDEGVYTCVAKNQYGTDES-RGRLIVLRAPRFLEKLPPRITAQVNSVVFLHCNADVDP 146
EG Y CV N +G+ S + +L V P F K P +T + ++ L C A P
Sbjct: 572 EFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSF-TKTPMDLTIRAGAMARLECAAVGHP 630
Query: 147 ILDTAYLWNHNGLRIKDSSDLYVNKRIKIDGGELTIYNVSLSDVGDYECVVKSAIGRISS 206
A W +G + + + I +V + D+G Y C +++ G IS+
Sbjct: 631 APQIA--WQKDG-GTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISA 687
Query: 207 HVQLRIEGPP 216
+ L + P
Sbjct: 688 NATLTVLETP 697
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.135 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,650,384
Number of Sequences: 224733
Number of extensions: 5609373
Number of successful extensions: 31213
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 731
Number of HSP's successfully gapped in prelim test: 945
Number of HSP's that attempted gapping in prelim test: 18832
Number of HSP's gapped (non-prelim): 7265
length of query: 674
length of database: 73,234,838
effective HSP length: 95
effective length of query: 579
effective length of database: 51,885,203
effective search space: 30041532537
effective search space used: 30041532537
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 69 (31.9 bits)
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