Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002355-TA|BGIBMGA002355-PA|IPR000672|Tetrahydrofolate
dehydrogenase/cyclohydrolase
(301 letters)
Database: spombe
5004 sequences; 2,362,478 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SPBC2G2.08 |ade9||C-1-tetrahydrofolatesynthase/methylenetetrahyd... 229 4e-61
SPBC839.16 |||C-1-tetrahydrofolate synthase|Schizosaccharomyces ... 224 1e-59
SPBC1711.04 |||methylenetetrahydrofolate reductase |Schizosaccha... 55 1e-08
SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces ... 33 0.038
SPAC56E4.04c |cut6||acetyl-CoA carboxylase|Schizosaccharomyces p... 31 0.15
SPAC1420.02c |cct5||chaperonin-containing T-complex epsilon subu... 29 0.62
SPAC1420.01c ||SPAC56E4.08c|DUF1752 family protein|Schizosacchar... 28 1.9
SPAC24C9.08 |||vacuolar carboxypeptidase |Schizosaccharomyces po... 28 1.9
SPBC428.01c |nup107|SPBC582.11c|nucleoporin Nup107|Schizosacchar... 27 2.5
SPCC737.08 |||midasin |Schizosaccharomyces pombe|chr 3|||Manual 26 5.8
SPBC18H10.08c |ubp4||ubiquitin C-terminal hydrolase Ubp4|Schizos... 26 7.6
>SPBC2G2.08 |ade9||C-1-
tetrahydrofolatesynthase/methylenetetrahydrofolatedehydr
ogenase/methylenetetrahydrofolatecyclohydrolase/formylte
trahydrofolatesynthetase|Schizosaccharomyces pombe|chr
2|||Manual
Length = 969
Score = 229 bits (560), Expect = 4e-61
Identities = 129/296 (43%), Positives = 181/296 (61%), Gaps = 15/296 (5%)
Query: 2 ARILDGKALAMEIKKELKQKI-AQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFV 60
A IL+GK LA ++++ + +++ A N P + + VG S+ YVR K +AA+ V
Sbjct: 33 ANILNGKLLARKLQRSVAEEVQALKAKDRNFKPALAIVQVGKREDSNVYVRMKEKAARLV 92
Query: 61 GIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDID 120
GID I LL E++ LN+D++V G+LVQLP+P +NER V ++I P KD+D
Sbjct: 93 GIDFKYCPFPETIQMPALLHELKKLNDDHTVHGVLVQLPLPKHLNERTVTESITPPKDVD 152
Query: 121 GFHIINIGRLCVD--LPTIVPATALAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMML 178
GF NIG L + P P T ++E+LK I G NAVV+GRS VG PI+ +L
Sbjct: 153 GFGAFNIGLLAKNDATPIHYPCTPKGIMELLKDNKISVAGLNAVVLGRSDIVGNPISYLL 212
Query: 179 HSDKRHESGLGMDATVTICHRYTPKDKLEAYCRNADIIITATGLPKLIKADMVKPGATII 238
D +ATVT+CH T KD ++ + NAD++I A G P+ ++ + +KPG+ ++
Sbjct: 213 RKD---------NATVTVCHSKT-KDLIQ-HISNADLVIAALGKPEFVRGEWLKPGSVVV 261
Query: 239 DVGITRITDENGKSRLVGDVDYEEVSKIAGAITPVPGGVGPMTVAMLMHNTFQAAQ 294
DVGI + NGK LVGDV +E SK+A +ITPVPGGVGPMTVAMLM N AA+
Sbjct: 262 DVGINAV-QRNGKRVLVGDVHFESASKVASSITPVPGGVGPMTVAMLMENIVNAAK 316
>SPBC839.16 |||C-1-tetrahydrofolate synthase|Schizosaccharomyces
pombe|chr 2|||Manual
Length = 937
Score = 224 bits (548), Expect = 1e-59
Identities = 126/298 (42%), Positives = 181/298 (60%), Gaps = 16/298 (5%)
Query: 1 MARILDGKALAMEIKKELKQKIAQWVSLGNRAP-TIRCIIVGDDPASHTYVRNKVEAAKF 59
MA +L+G +LA ++++EL+++I+ S+ +++ I VG S+ YVR K AA
Sbjct: 1 MALLLEGTSLARKVREELREQISSIKSVDPYFNVSLKIIQVGGREDSNVYVRMKTRAANE 60
Query: 60 VGIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDI 119
GI +N DITE LL I+ NED +V GI+VQLP+P INE+ + +A+APEKD+
Sbjct: 61 AGISCEHVNFPEDITEYDLLLAIKGFNEDPTVHGIIVQLPLPAHINEQIITEAVAPEKDV 120
Query: 120 DGFHIINIGRLC--VDLPTIVPATALAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMM 177
DGF N+G+L P T ++ +LK + I+ G++AVVIGRS VG P++++
Sbjct: 121 DGFCETNLGKLTKREGQPLFTACTPKGIMCILKHYGINVQGKHAVVIGRSNIVGRPMSIL 180
Query: 178 LHSDKRHESGLGMDATVTICHRYTPKDKLEAYCRNADIIITATGLPKLIKADMVKPGATI 237
L +ATVT+CH T + + R ADI++ A G+P +KAD +K G
Sbjct: 181 LEK---------ANATVTLCHSKT--ESIADIVRTADIVVAAIGIPHFVKADWLKKGVVA 229
Query: 238 IDVGITRITDENGKS--RLVGDVDYEEVSKIAGAITPVPGGVGPMTVAMLMHNTFQAA 293
IDVGI I D KS RL GD+D+E ++A AITPVPG VGPMTVAML+ N ++A
Sbjct: 230 IDVGINSIPDATKKSGYRLTGDIDFENAKEVASAITPVPGSVGPMTVAMLLQNVVESA 287
>SPBC1711.04 |||methylenetetrahydrofolate reductase
|Schizosaccharomyces pombe|chr 2|||Manual
Length = 320
Score = 55.2 bits (127), Expect = 1e-08
Identities = 43/189 (22%), Positives = 89/189 (47%), Gaps = 22/189 (11%)
Query: 11 AMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRD 70
A + + +++ Q V+L AP + + DPA+ Y + +G
Sbjct: 18 ASRVAETFVEQLKQHVNLFEFAPKLVGFLSNSDPAARMYADWTNKTCTEIGFQYEL---- 73
Query: 71 SDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGF---HIINI 127
++ ++ L I N D SV+GI++ PV + ++ + ++P+KD++G +++N+
Sbjct: 74 REVPKDDLEDAIVEANNDPSVNGIMIYFPVFNDGQDQYLQQVVSPDKDVEGLCHKYVMNM 133
Query: 128 GRLCVDL------PTIVPATALAVVEMLKRFNI---------DTFGRNAVVIGRSKNVGM 172
L +I+P T LA+V++L+ + +G+ ++ RS+ VG
Sbjct: 134 YHNIRHLDPEKTKKSILPCTPLAIVKILEYLGVYNKIINYGNRLYGKTITIVNRSEIVGR 193
Query: 173 PIAMMLHSD 181
P+A +L +D
Sbjct: 194 PLAALLAND 202
>SPCC74.06 |mak3|phk2|histidine kinase Mak3 |Schizosaccharomyces
pombe|chr 3|||Manual
Length = 2344
Score = 33.5 bits (73), Expect = 0.038
Identities = 14/47 (29%), Positives = 28/47 (59%)
Query: 75 EEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 121
EEQ+ ++ + +D+S++ +L+ L + D + R C IA E ++ G
Sbjct: 1438 EEQIDDDVSPVAQDSSLEELLISLDIIDLTSVMRSCQTIASEIELTG 1484
>SPAC56E4.04c |cut6||acetyl-CoA carboxylase|Schizosaccharomyces
pombe|chr 1|||Manual
Length = 2280
Score = 31.5 bits (68), Expect = 0.15
Identities = 18/58 (31%), Positives = 29/58 (50%)
Query: 217 ITATGLPKLIKADMVKPGATIIDVGITRITDENGKSRLVGDVDYEEVSKIAGAITPVP 274
I TG P L K + + + +G T++ NG S L D++ +SKI I+ +P
Sbjct: 1795 IILTGAPALNKVLGREVYTSNLQLGGTQVMHRNGISHLTSQDDFDGISKIVNWISYIP 1852
>SPAC1420.02c |cct5||chaperonin-containing T-complex epsilon subunit
Cct5|Schizosaccharomyces pombe|chr 1|||Manual
Length = 546
Score = 29.5 bits (63), Expect = 0.62
Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 42 DDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDN-SVDGILVQLPV 100
DD A+H ++N + A ++VG I + T +++ ++L+ D GI+ ++
Sbjct: 309 DDEANHLLLQNNLPAVRWVG--GPEIELIAIATNGRIVPRFEDLSSDKLGSAGIVREVSF 366
Query: 101 PDTINERRVCDAIAPEKDIDGFHIINIGRLCVDLPTIVPATALAVVEMLKRFNIDTFGRN 160
T ++ V + A + + F + ++ VD AL VV L R N +G
Sbjct: 367 GTTRDKILVIEKCANSRAVTVF-VRGSNKMIVDEAKRALHDALCVVRNLIRDNRVVYGGG 425
Query: 161 AVVIGRS 167
A I S
Sbjct: 426 AAEISCS 432
>SPAC1420.01c ||SPAC56E4.08c|DUF1752 family
protein|Schizosaccharomyces pombe|chr 1|||Manual
Length = 580
Score = 27.9 bits (59), Expect = 1.9
Identities = 13/27 (48%), Positives = 17/27 (62%)
Query: 64 ALTINRDSDITEEQLLSEIQNLNEDNS 90
AL + RD+DI LS+ N+N DNS
Sbjct: 468 ALNLPRDTDIKATPNLSQSGNINSDNS 494
>SPAC24C9.08 |||vacuolar carboxypeptidase |Schizosaccharomyces
pombe|chr 1|||Manual
Length = 596
Score = 27.9 bits (59), Expect = 1.9
Identities = 27/86 (31%), Positives = 35/86 (40%), Gaps = 4/86 (4%)
Query: 47 HTYVRNKVEAAKFVG--IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTI 104
H Y R + V ++AL I SD EQ + I + D V G LP+ +
Sbjct: 224 HVYSRGAADDKNSVVAILEALEILAISDYKPEQTV--IASFGFDEEVSGYRGALPLAHKL 281
Query: 105 NERRVCDAIAPEKDIDGFHIINIGRL 130
ER D +A D GF I G L
Sbjct: 282 YERYGKDGVALILDEGGFTINLFGTL 307
>SPBC428.01c |nup107|SPBC582.11c|nucleoporin
Nup107|Schizosaccharomyces pombe|chr 2|||Manual
Length = 794
Score = 27.5 bits (58), Expect = 2.5
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 88 DNSVDGILVQLPVPDTINE--RRVCDAIAPEKDIDGFHIINIGRLCVDLPTIV 138
DN +D +L + E RR C A+ K ID + G LC DL +++
Sbjct: 272 DNLIDDVLQSETSGNKRKELLRRSCLALTKNKRIDSYERALYGALCGDLNSVL 324
>SPCC737.08 |||midasin |Schizosaccharomyces pombe|chr 3|||Manual
Length = 4717
Score = 26.2 bits (55), Expect = 5.8
Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 37 CIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILV 96
CI+VGD T + + A I + +N D+D + L+ E + ++ +
Sbjct: 1872 CILVGDTATGKTCILRLLAAIAGAKIKEMAVNSDTDTMD--LIGEYEQIDISRKASELFT 1929
Query: 97 QL 98
L
Sbjct: 1930 DL 1931
>SPBC18H10.08c |ubp4||ubiquitin C-terminal hydrolase
Ubp4|Schizosaccharomyces pombe|chr 2|||Manual
Length = 438
Score = 25.8 bits (54), Expect = 7.6
Identities = 13/42 (30%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 53 KVEAAKFVGIDALTINRDS-DITEEQLLSEIQNLNEDNSVDG 93
K+ +A F + ++ +N I+ L +Q+LN D S+DG
Sbjct: 121 KITSAFFSLLQSVLLNHGQRSISPRNFLEIVQSLNRDFSIDG 162
Database: spombe
Posted date: Oct 3, 2007 3:31 PM
Number of letters in database: 2,362,478
Number of sequences in database: 5004
Lambda K H
0.319 0.136 0.388
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,308,894
Number of Sequences: 5004
Number of extensions: 54234
Number of successful extensions: 147
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 130
Number of HSP's gapped (non-prelim): 12
length of query: 301
length of database: 2,362,478
effective HSP length: 72
effective length of query: 229
effective length of database: 2,002,190
effective search space: 458501510
effective search space used: 458501510
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 54 (25.8 bits)
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