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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA002355-TA|BGIBMGA002355-PA|IPR000672|Tetrahydrofolate
dehydrogenase/cyclohydrolase
         (301 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_18696| Best HMM Match : THF_DHG_CYH_C (HMM E-Value=0)              112   4e-25
SB_21968| Best HMM Match : THF_DHG_CYH (HMM E-Value=0.0018)            62   7e-10
SB_57521| Best HMM Match : rve (HMM E-Value=0.13)                      33   0.38 
SB_53724| Best HMM Match : No HMM Matches (HMM E-Value=.)              32   0.66 
SB_19298| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.2  
SB_52945| Best HMM Match : RVT_1 (HMM E-Value=7.2e-19)                 31   1.2  
SB_39311| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.5  
SB_15756| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.5  
SB_48350| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.5  
SB_41460| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.5  
SB_39948| Best HMM Match : No HMM Matches (HMM E-Value=.)              31   1.5  
SB_22430| Best HMM Match : DUF498 (HMM E-Value=3.7)                    31   1.5  
SB_49934| Best HMM Match : No HMM Matches (HMM E-Value=.)              30   2.0  
SB_17836| Best HMM Match : rve (HMM E-Value=7.3e-14)                   30   2.7  
SB_51222| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   3.5  
SB_19469| Best HMM Match : Peptidase_A16_N (HMM E-Value=0.00048)       29   4.7  
SB_25340| Best HMM Match : No HMM Matches (HMM E-Value=.)              29   6.1  
SB_9725| Best HMM Match : GETHR (HMM E-Value=0.00026)                  29   6.1  
SB_13238| Best HMM Match : rve (HMM E-Value=1.1e-13)                   28   8.1  

>SB_18696| Best HMM Match : THF_DHG_CYH_C (HMM E-Value=0)
          Length = 119

 Score =  112 bits (269), Expect = 4e-25
 Identities = 60/109 (55%), Positives = 71/109 (65%), Gaps = 4/109 (3%)

Query: 191 DATVTICHRYTPKDKLEAYCRNADIIITATGLPKLIKADMVKPGATIIDVGITRITDENG 250
           +ATVTICH  T    L+  C  ADII+ A G PK I ADMVK GA ++DVGI RI D   
Sbjct: 13  NATVTICHSRTKN--LKEMCLQADIIVAAIGKPKFITADMVKEGAIVLDVGINRIDDATR 70

Query: 251 KS--RLVGDVDYEEVSKIAGAITPVPGGVGPMTVAMLMHNTFQAAQSQA 297
           KS  RLVGDVD++ V      ITPVPGGVG MT+  LM NT +AA+  +
Sbjct: 71  KSGKRLVGDVDFDNVKDKCSFITPVPGGVGLMTICGLMMNTLEAAKQHS 119


>SB_21968| Best HMM Match : THF_DHG_CYH (HMM E-Value=0.0018)
          Length = 101

 Score = 61.7 bits (143), Expect = 7e-10
 Identities = 35/84 (41%), Positives = 55/84 (65%), Gaps = 6/84 (7%)

Query: 73  ITEEQLLSEIQNLNEDNSVDGILVQLPVPDTIN--ERRVC-DAIAPEKDIDGFHIINIGR 129
           + + Q+L  +  LN+D+++ GI+VQLP PD+ N  +  +C +A+ PEKD+DG H  N GR
Sbjct: 17  LCDMQVLKAVDELNKDSAIHGIIVQLP-PDSENPIDPGICTNAVIPEKDVDGLHDENAGR 75

Query: 130 LC-VDLPT-IVPATALAVVEMLKR 151
           L   +L T IVP T    +E++K+
Sbjct: 76  LARGELATCIVPCTPRGCLELIKK 99


>SB_57521| Best HMM Match : rve (HMM E-Value=0.13)
          Length = 1105

 Score = 32.7 bits (71), Expect = 0.38
 Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 5/59 (8%)

Query: 44   PASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLS-EIQNLNEDNSVDGILVQLPVP 101
            PAS  Y+ N  + ++  GI   T      I + Q+ S + + +N+ N +DG+ V++P+P
Sbjct: 1017 PASEPYIANPAQFSQPTGITHNT----PQIHKSQVSSHQAEEINKSNPMDGLAVEIPLP 1071


>SB_53724| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1005

 Score = 31.9 bits (69), Expect = 0.66
 Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 9/95 (9%)

Query: 154 IDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGLGMDATVTICHRYTPKDKLEAYCRNA 213
           +  F   A V  + +++G    + +H ++  E G G    ++  +     +     CR  
Sbjct: 184 VRAFDTRAAVKEQVQSLGAEF-LEIHVEESGEGGGGYAKEMSPEYIKAEMELFAKQCREV 242

Query: 214 DIIITATGL-----PKLIKADMV---KPGATIIDV 240
           DI+IT   +     PKLI  +MV   KPG+ I+D+
Sbjct: 243 DIVITTALIPGKPAPKLISKEMVESMKPGSVIVDL 277


>SB_19298| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 219

 Score = 31.1 bits (67), Expect = 1.2
 Identities = 16/59 (27%), Positives = 33/59 (55%), Gaps = 5/59 (8%)

Query: 44  PASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLS-EIQNLNEDNSVDGILVQLPVP 101
           PAS  Y+ N  + ++  GI     +    I + Q+ S + + +N+ N +DG+ +++P+P
Sbjct: 131 PASEPYIANPAQFSQPTGIT----HNAPQIHKSQVSSHQDEEINKSNPMDGLAIEIPLP 185


>SB_52945| Best HMM Match : RVT_1 (HMM E-Value=7.2e-19)
          Length = 429

 Score = 31.1 bits (67), Expect = 1.2
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 294 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMVVRKPLHKSPKRLQGM 339


>SB_39311| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 916

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 284 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQGM 329


>SB_15756| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 516

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 184 HESGLGMDATVTICHRYTPKDKLEAYCRNADIIITAT---GLPKLIKADMVKPGATIIDV 240
           + +G   D T   C+RY    KL     N D+++T        + +K +   PG  + D+
Sbjct: 235 YSTGACYDTTFASCNRYDKFSKLV----NQDVLLTQVIRFANAEYLKNNGSYPGVKVDDI 290

Query: 241 GITRITDENGKSRLVGDVDYEEVSKIAGAITP 272
            +      +G SR + ++  E+V K  G   P
Sbjct: 291 RVEADAMISGLSRYLENIHGEQVCKTIGCELP 322


>SB_48350| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 883

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 375 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQGM 420


>SB_41460| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1669

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 620 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQGM 665


>SB_39948| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 727

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 276 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQGM 321


>SB_22430| Best HMM Match : DUF498 (HMM E-Value=3.7)
          Length = 214

 Score = 30.7 bits (66), Expect = 1.5
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESGL 188
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G+
Sbjct: 19  LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQGM 64


>SB_49934| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 221

 Score = 30.3 bits (65), Expect = 2.0
 Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 55  EAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIA 114
           + + F  +D L+   D D  +     E+ NL+  N+VD +  +  V D ++ R   D ++
Sbjct: 101 DLSPFNDVDGLSSRNDVD--DRSSRDEVDNLSSRNNVDDLSSRNDV-DNLSSRNKVDGLS 157

Query: 115 PEKDID 120
              D+D
Sbjct: 158 SRNDVD 163


>SB_17836| Best HMM Match : rve (HMM E-Value=7.3e-14)
          Length = 713

 Score = 29.9 bits (64), Expect = 2.7
 Identities = 16/45 (35%), Positives = 23/45 (51%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESG 187
           LA+V  L+RF+  TFGR  +V    K + M +   LH   +   G
Sbjct: 163 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKRLQG 207


>SB_51222| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 2520

 Score = 29.5 bits (63), Expect = 3.5
 Identities = 14/29 (48%), Positives = 20/29 (68%), Gaps = 2/29 (6%)

Query: 62  IDALTINRDSDIT--EEQLLSEIQNLNED 88
           IDAL  N+D D+T  +E+L SE+Q   E+
Sbjct: 663 IDALKQNKDKDVTALKEELTSEVQKYKEE 691


>SB_19469| Best HMM Match : Peptidase_A16_N (HMM E-Value=0.00048)
          Length = 1347

 Score = 29.1 bits (62), Expect = 4.7
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLH-SDKR 183
           LA+V  L+RF+  TFGR  +V    K + M +   LH S KR
Sbjct: 232 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIVRKPLHKSPKR 273


>SB_25340| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 1105

 Score = 28.7 bits (61), Expect = 6.1
 Identities = 12/41 (29%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 5    LDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPA 45
            +DGK   +  + +L   I + ++  N +P+  CI+ GD P+
Sbjct: 994  IDGKLFVVNEEDQLMASITKQIAASN-SPSYTCILTGDAPS 1033


>SB_9725| Best HMM Match : GETHR (HMM E-Value=0.00026)
          Length = 338

 Score = 28.7 bits (61), Expect = 6.1
 Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 11/78 (14%)

Query: 151 RFNIDT--FGRNAVVI------GRSKNVGMPIAMMLHSDKRHESGL-GMDATVTICHRYT 201
           R+N  T   GRNA  +       ++K  G+    ++H+    ++ L G+DAT  I  RY 
Sbjct: 229 RYNAKTKLAGRNATEVIHARYNAKTKLAGLDATEVIHARYNAKTKLAGLDATEVIHARYN 288

Query: 202 PKDKLEAYCRNADIIITA 219
            K KL    RNA  +I A
Sbjct: 289 AKTKLAG--RNATEVIHA 304


>SB_13238| Best HMM Match : rve (HMM E-Value=1.1e-13)
          Length = 637

 Score = 28.3 bits (60), Expect = 8.1
 Identities = 16/45 (35%), Positives = 22/45 (48%)

Query: 143 LAVVEMLKRFNIDTFGRNAVVIGRSKNVGMPIAMMLHSDKRHESG 187
           LA+V  L+RF+  TFGR  +V    K + M     LH   +   G
Sbjct: 345 LAIVFSLERFHQYTFGRKTIVHSDHKPLEMIARKPLHKSPKRLQG 389


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.319    0.136    0.388 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 9,790,754
Number of Sequences: 59808
Number of extensions: 409833
Number of successful extensions: 923
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 906
Number of HSP's gapped (non-prelim): 23
length of query: 301
length of database: 16,821,457
effective HSP length: 82
effective length of query: 219
effective length of database: 11,917,201
effective search space: 2609867019
effective search space used: 2609867019
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 60 (28.3 bits)

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