Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002350-TA|BGIBMGA002350-PA|IPR000719|Protein kinase,
IPR002290|Serine/threonine protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR011009|Protein kinase-like
(252 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 235 1e-61
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 234 2e-61
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 234 2e-61
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 234 2e-61
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 234 2e-61
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 234 2e-61
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 234 3e-61
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 234 3e-61
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 234 3e-61
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 234 3e-61
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 233 3e-61
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 233 3e-61
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 232 8e-61
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 226 5e-59
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 226 5e-59
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 226 5e-59
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 226 5e-59
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 226 5e-59
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 226 5e-59
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 226 5e-59
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 226 5e-59
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 226 5e-59
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 226 7e-59
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 225 9e-59
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 217 3e-56
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 208 1e-53
AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein. 170 3e-42
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 142 1e-33
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 142 1e-33
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 130 3e-30
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 130 5e-30
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 129 1e-29
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 128 1e-29
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 128 1e-29
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 128 1e-29
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 128 1e-29
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 128 1e-29
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 128 1e-29
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 128 1e-29
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 128 2e-29
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 128 2e-29
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 128 2e-29
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 128 2e-29
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 127 3e-29
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 127 3e-29
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 127 3e-29
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 127 3e-29
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 127 3e-29
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 127 3e-29
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 127 3e-29
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 126 6e-29
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 126 6e-29
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 126 6e-29
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 126 6e-29
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 126 6e-29
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 126 6e-29
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 126 6e-29
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 126 6e-29
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 126 6e-29
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 126 1e-28
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 124 4e-28
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 124 4e-28
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 123 7e-28
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 123 7e-28
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 123 7e-28
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 122 9e-28
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 122 9e-28
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 122 9e-28
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 122 9e-28
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 122 9e-28
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 122 9e-28
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 122 9e-28
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 122 9e-28
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 122 9e-28
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 122 9e-28
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 122 9e-28
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 122 9e-28
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 122 9e-28
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 122 9e-28
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 121 2e-27
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 121 2e-27
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 121 2e-27
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 121 2e-27
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 121 3e-27
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 121 3e-27
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 121 3e-27
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 121 3e-27
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 120 4e-27
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 120 4e-27
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 120 4e-27
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 120 4e-27
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 120 4e-27
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 120 4e-27
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 119 1e-26
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 118 1e-26
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 118 1e-26
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 118 1e-26
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 118 1e-26
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 118 2e-26
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 118 2e-26
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 118 2e-26
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 118 3e-26
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 118 3e-26
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 118 3e-26
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 118 3e-26
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 118 3e-26
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 118 3e-26
X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein ... 117 5e-26
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase... 117 5e-26
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 117 5e-26
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 117 5e-26
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 116 6e-26
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 116 6e-26
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 116 6e-26
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 116 6e-26
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 116 6e-26
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 116 8e-26
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 116 8e-26
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 116 8e-26
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 116 8e-26
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 116 8e-26
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 116 1e-25
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 116 1e-25
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 115 1e-25
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 115 2e-25
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 114 2e-25
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 114 2e-25
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 114 2e-25
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 113 4e-25
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 113 4e-25
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 113 4e-25
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 113 6e-25
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 113 6e-25
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 113 7e-25
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 113 7e-25
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 113 7e-25
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 113 7e-25
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 113 7e-25
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 113 7e-25
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 112 1e-24
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 112 1e-24
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 112 1e-24
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 111 2e-24
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 110 4e-24
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 110 4e-24
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 110 4e-24
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 110 4e-24
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 110 4e-24
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 109 7e-24
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 109 7e-24
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 109 7e-24
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 109 7e-24
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 109 7e-24
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 109 7e-24
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 109 7e-24
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 109 7e-24
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 109 9e-24
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 109 9e-24
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 109 9e-24
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 109 9e-24
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 109 9e-24
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 109 9e-24
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 108 2e-23
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 108 2e-23
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 108 2e-23
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 108 2e-23
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 108 2e-23
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 108 2e-23
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 108 2e-23
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 108 2e-23
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 108 2e-23
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 108 2e-23
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 108 2e-23
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 108 2e-23
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 108 2e-23
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 108 2e-23
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 107 3e-23
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 107 3e-23
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 107 3e-23
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 107 3e-23
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 107 3e-23
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 107 3e-23
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 107 3e-23
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 107 3e-23
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 107 3e-23
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 107 5e-23
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 107 5e-23
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 107 5e-23
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 107 5e-23
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 107 5e-23
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 106 6e-23
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 106 6e-23
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 106 6e-23
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 106 6e-23
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 106 9e-23
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 106 9e-23
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 106 9e-23
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 105 1e-22
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 105 1e-22
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 105 1e-22
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 105 1e-22
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 105 1e-22
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 105 1e-22
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 105 1e-22
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 105 1e-22
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 105 1e-22
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 105 1e-22
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 105 2e-22
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 105 2e-22
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 105 2e-22
AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein. 105 2e-22
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 104 3e-22
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 104 3e-22
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 104 3e-22
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 104 3e-22
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 104 3e-22
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 104 3e-22
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 104 3e-22
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 104 3e-22
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 104 3e-22
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 104 3e-22
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 104 3e-22
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 104 3e-22
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 104 3e-22
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 104 3e-22
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 104 3e-22
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 104 3e-22
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 104 3e-22
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 104 3e-22
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 104 3e-22
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 103 6e-22
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 103 6e-22
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 103 6e-22
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 103 6e-22
Z98752-6|CAI42313.1| 198|Homo sapiens serum/glucocorticoid regu... 103 8e-22
X62071-1|CAA43985.1| 298|Homo sapiens cdk2 protein. 103 8e-22
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 103 8e-22
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 103 8e-22
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 103 8e-22
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 103 8e-22
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 103 8e-22
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 103 8e-22
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 103 8e-22
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 103 8e-22
Y00272-1|CAA68376.1| 297|Homo sapiens protein ( Human cell cycl... 102 1e-21
X05360-1|CAA28963.1| 297|Homo sapiens protein ( Human CDC2 gene... 102 1e-21
BT007004-1|AAP35650.1| 297|Homo sapiens cell division cycle 2, ... 102 1e-21
BC107750-1|AAI07751.1| 225|Homo sapiens CDC2 protein protein. 102 1e-21
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 102 1e-21
BC014563-1|AAH14563.1| 297|Homo sapiens cell division cycle 2, ... 102 1e-21
AF512554-1|AAM34793.1| 297|Homo sapiens cell division cycle 2, ... 102 1e-21
X61622-1|CAA43807.1| 298|Homo sapiens CDK2 protein. 102 1e-21
M68520-1|AAA35667.1| 298|Homo sapiens cdc2-related protein kina... 102 1e-21
BT006821-1|AAP35467.1| 298|Homo sapiens cyclin-dependent kinase... 102 1e-21
BC003065-1|AAH03065.1| 298|Homo sapiens cyclin-dependent kinase... 102 1e-21
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 102 1e-21
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 102 1e-21
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 102 1e-21
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 102 1e-21
AF512553-1|AAM34794.1| 298|Homo sapiens cyclin-dependent kinase... 102 1e-21
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 101 3e-21
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 101 3e-21
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 101 3e-21
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 100 4e-21
BC038238-1|AAH38238.1| 414|Homo sapiens serine/threonine kinase... 100 4e-21
AY098866-1|AAM21719.1| 486|Homo sapiens PKE protein kinase prot... 100 4e-21
AL590105-1|CAI13011.1| 486|Homo sapiens protein kinase (PKE) pr... 100 4e-21
AL512622-1|CAI12181.1| 486|Homo sapiens protein kinase (PKE) pr... 100 4e-21
AJ250839-1|CAB76471.1| 414|Homo sapiens serine/threonine protei... 100 4e-21
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 100 6e-21
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 100 6e-21
M80335-1|AAA60094.1| 207|Homo sapiens protein kinase A-alpha pr... 100 6e-21
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 100 6e-21
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 100 6e-21
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 100 1e-20
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 100 1e-20
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 99 1e-20
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 99 1e-20
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 99 1e-20
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 98 3e-20
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 97 4e-20
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 97 4e-20
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 97 4e-20
AF208004-1|AAG35720.1| 181|Homo sapiens cAMP-dependent protein ... 97 4e-20
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 97 4e-20
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 97 4e-20
X66358-1|CAA47002.1| 358|Homo sapiens serine/threonine protein ... 97 5e-20
BC104977-1|AAI04978.1| 358|Homo sapiens cyclin-dependent kinase... 97 5e-20
AY525548-1|AAS00095.1| 358|Homo sapiens cyclin-dependent kinase... 97 5e-20
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 97 7e-20
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 97 7e-20
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 97 7e-20
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 97 7e-20
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 97 7e-20
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 97 7e-20
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 97 7e-20
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 97 7e-20
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 97 7e-20
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 97 7e-20
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 97 7e-20
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 97 7e-20
AK027302-1|BAB55026.1| 208|Homo sapiens protein ( Homo sapiens ... 96 9e-20
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 96 1e-19
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 96 1e-19
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 96 1e-19
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 96 1e-19
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 96 1e-19
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 96 1e-19
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 96 1e-19
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 95 2e-19
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 95 2e-19
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 95 2e-19
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 95 2e-19
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 95 3e-19
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 95 3e-19
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 95 3e-19
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 95 3e-19
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 95 3e-19
BC009107-1|AAH09107.1| 879|Homo sapiens microtubule associated ... 95 3e-19
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 95 3e-19
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 95 3e-19
AL160291-7|CAI16908.1| 878|Homo sapiens novel protein kinase do... 95 3e-19
AL160291-6|CAI16909.1| 879|Homo sapiens novel protein kinase do... 95 3e-19
AL160291-5|CAI16910.1| 840|Homo sapiens novel protein kinase do... 95 3e-19
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 95 3e-19
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 95 3e-19
AK074804-1|BAC11218.1| 840|Homo sapiens protein ( Homo sapiens ... 95 3e-19
AK027719-1|BAB55321.1| 878|Homo sapiens protein ( Homo sapiens ... 95 3e-19
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 95 3e-19
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 95 3e-19
AL450063-5|CAI16848.1| 186|Homo sapiens protein kinase, cAMP-de... 94 4e-19
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 93 6e-19
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 93 6e-19
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 93 6e-19
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 93 6e-19
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 93 6e-19
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 93 6e-19
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 93 6e-19
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 93 6e-19
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 93 8e-19
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 93 8e-19
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 93 8e-19
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 93 8e-19
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 93 8e-19
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 93 8e-19
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 93 8e-19
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 93 8e-19
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 93 8e-19
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 93 8e-19
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 93 8e-19
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 93 8e-19
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 93 8e-19
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 93 8e-19
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 93 8e-19
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 93 1e-18
AF164041-1|AAD50272.1| 1130|Homo sapiens WARTS protein kinase pr... 93 1e-18
AF104413-1|AAD16882.1| 1130|Homo sapiens large tumor suppressor ... 93 1e-18
AB209426-1|BAD92663.1| 830|Homo sapiens LATS homolog 1 variant ... 93 1e-18
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 92 1e-18
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 92 2e-18
BC028603-1|AAH28603.1| 464|Homo sapiens serine/threonine kinase... 92 2e-18
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 92 2e-18
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 92 2e-18
AB023182-1|BAA76809.2| 489|Homo sapiens KIAA0965 protein protein. 92 2e-18
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 91 3e-18
AY166586-1|AAN86031.1| 1638|Homo sapiens CDC42-binding protein k... 91 3e-18
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 91 3e-18
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 91 3e-18
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 91 3e-18
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 91 3e-18
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 91 3e-18
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 91 3e-18
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 91 3e-18
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 91 3e-18
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 91 3e-18
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 91 3e-18
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 91 3e-18
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 91 3e-18
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 91 3e-18
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 91 3e-18
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 91 3e-18
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 91 3e-18
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 91 3e-18
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 91 3e-18
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 91 3e-18
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 91 3e-18
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL162724-7|CAH70252.1| 222|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL162724-6|CAH70251.1| 220|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL162724-5|CAH70250.1| 219|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 91 3e-18
AL137846-11|CAI10881.1| 222|Homo sapiens NIMA (never in mitosis... 91 3e-18
AL137846-10|CAI10880.1| 220|Homo sapiens NIMA (never in mitosis... 91 3e-18
AL137846-9|CAI10879.1| 219|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 91 3e-18
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 91 3e-18
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 91 3e-18
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 91 5e-18
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 91 5e-18
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 91 5e-18
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 90 6e-18
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 90 6e-18
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 90 6e-18
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 90 6e-18
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 90 6e-18
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 90 6e-18
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 90 6e-18
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 90 6e-18
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 89 1e-17
AL162724-4|CAH70249.1| 207|Homo sapiens NIMA (never in mitosis ... 89 1e-17
AL137846-8|CAI10878.1| 207|Homo sapiens NIMA (never in mitosis ... 89 1e-17
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 89 2e-17
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 89 2e-17
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 89 2e-17
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 89 2e-17
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 89 2e-17
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 89 2e-17
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 89 2e-17
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 89 2e-17
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 89 2e-17
X66364-1|CAA47007.1| 292|Homo sapiens serine/threonine protein ... 88 2e-17
BT006680-1|AAP35326.1| 292|Homo sapiens cyclin-dependent kinase... 88 2e-17
BC005115-1|AAH05115.1| 292|Homo sapiens cyclin-dependent kinase... 88 2e-17
AY049778-1|AAL15435.1| 292|Homo sapiens cyclin-dependent kinase... 88 2e-17
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 88 2e-17
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 88 3e-17
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 88 3e-17
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 88 3e-17
AB020641-1|BAA74857.2| 453|Homo sapiens KIAA0834 protein protein. 88 3e-17
Y13120-1|CAA73587.1| 346|Homo sapiens serine/threonine protein ... 87 4e-17
X79193-1|CAA55785.1| 346|Homo sapiens MO15/CDK-activating kinas... 87 4e-17
X77743-1|CAA54793.1| 346|Homo sapiens CDK activating kinase pro... 87 4e-17
X77303-1|CAA54508.1| 346|Homo sapiens Cdk-activating kinase pro... 87 4e-17
L20320-1|AAA36657.1| 346|Homo sapiens protein serine/threonine ... 87 4e-17
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 87 4e-17
BC000834-1|AAH00834.1| 346|Homo sapiens cyclin-dependent kinase... 87 4e-17
AY130859-1|AAM77799.1| 346|Homo sapiens cyclin-dependent kinase... 87 4e-17
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 87 4e-17
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 87 4e-17
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 87 4e-17
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 87 6e-17
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 87 6e-17
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 87 7e-17
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 87 7e-17
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 87 7e-17
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 87 7e-17
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 87 7e-17
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 87 7e-17
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 87 7e-17
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 87 7e-17
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 87 7e-17
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 87 7e-17
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 87 7e-17
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 87 7e-17
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 235 bits (575), Expect = 1e-61
Identities = 120/233 (51%), Positives = 155/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 8 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 67
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD RR+YL++E+A GELYK L S + E + A I +VADA+ YCH
Sbjct: 68 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEEVADALTYCHD 125
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPERKTMCGTLDYLPPEMIEGRTYDEK 185
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 186 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 238
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 234 bits (573), Expect = 2e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 234 bits (573), Expect = 2e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 234 bits (573), Expect = 2e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 234 bits (573), Expect = 2e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 234 bits (573), Expect = 2e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 234 bits (572), Expect = 3e-61
Identities = 119/233 (51%), Positives = 155/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 8 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 67
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD RR+YL++E+A GELYK L S + E + A I ++ADA+ YCH
Sbjct: 68 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELADALTYCHD 125
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 126 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEK 185
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 186 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 238
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 234 bits (572), Expect = 3e-61
Identities = 119/233 (51%), Positives = 155/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 39 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 98
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD RR+YL++E+A GELYK L S + E + A I ++ADA+ YCH
Sbjct: 99 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELADALTYCHD 156
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 157 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEK 216
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 217 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 269
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 234 bits (572), Expect = 3e-61
Identities = 119/233 (51%), Positives = 155/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 23 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 82
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD RR+YL++E+A GELYK L S + E + A I ++ADA+ YCH
Sbjct: 83 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELADALTYCHD 140
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 141 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEK 200
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 201 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 253
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 234 bits (572), Expect = 3e-61
Identities = 119/233 (51%), Positives = 155/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 42 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 101
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD RR+YL++E+A GELYK L S + E + A I ++ADA+ YCH
Sbjct: 102 NILRLYNYFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELADALTYCHD 159
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEK 219
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 220 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 272
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 233 bits (571), Expect = 3e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 103 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 162
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 163 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 220
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 221 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 280
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 281 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLR--HN 338
Query: 245 AALSIPL 251
+ +PL
Sbjct: 339 PSERLPL 345
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 233 bits (571), Expect = 3e-61
Identities = 122/247 (49%), Positives = 163/247 (65%), Gaps = 27/247 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ +++
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLR--HN 311
Query: 245 AALSIPL 251
+ +PL
Sbjct: 312 PSERLPL 318
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 232 bits (568), Expect = 8e-61
Identities = 119/233 (51%), Positives = 154/233 (66%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AR K++ F+VA+K LFKSQI K E Q+ REIEIQ+HL+H
Sbjct: 42 DFEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHP 101
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL FHD RR+YL++E+A GELYK L S + E + A I ++ADA+ YCH
Sbjct: 102 NILRLYNHFHDARRVYLILEYAPRGELYKELQKSE--KLDEQRTATIIEELADALTYCHD 159
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ F G++K+ADF EMI+ YD
Sbjct: 160 KKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEK 219
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD WCIGVL YE LVG PPFE+ +TY RIL +D+ +P +P GA+DLIS+
Sbjct: 220 VDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGARDLISR 272
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 226 bits (553), Expect = 5e-59
Identities = 114/254 (44%), Positives = 165/254 (64%), Gaps = 27/254 (10%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI ++ +
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTF 348
Query: 224 PSHIPDGAKDLISK 237
P + +GA+DLIS+
Sbjct: 349 PDFVTEGARDLISR 362
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 226 bits (553), Expect = 5e-59
Identities = 121/250 (48%), Positives = 163/250 (65%), Gaps = 30/250 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAA---RYIYQVADAVEY 144
NILRL +F+D RRIYL++E+A G LYK L + F E + A R + ++ADA+ Y
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGMLYKELHKT--CTFDEQRTATVRRIMEELADALMY 193
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVY 181
CH VIHRDIKPEN+L+ G+LK+ADF EMI+ ++
Sbjct: 194 CHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMH 253
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGW 241
+ VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK
Sbjct: 254 NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR- 312
Query: 242 FHSAALSIPL 251
H+ + +PL
Sbjct: 313 -HNPSERLPL 321
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 226 bits (552), Expect = 7e-59
Identities = 121/247 (48%), Positives = 161/247 (65%), Gaps = 28/247 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +F+D RRIYL++E+A GELYK L S F E + A + ++ADA+ YCH
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGELYKELQKS--CTFDEQRTATIMEELADALMYCHG 193
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ G+LK+ADF EMI+ + +
Sbjct: 194 KKVIHRDIKPENLLLGLKGELKIADFGWSVHATSLRRKTMCGTLDYLPPEMIEGRIDNEK 253
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGWFHS 244
VD WCIGVL YE LVG PFE+ ++TY RI+ +D+ +P+ +P GA+DLISK H+
Sbjct: 254 VDLWCIGVLCYELLVGN-PFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR--HN 310
Query: 245 AALSIPL 251
+ +PL
Sbjct: 311 PSERLPL 317
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 225 bits (551), Expect = 9e-59
Identities = 121/250 (48%), Positives = 162/250 (64%), Gaps = 30/250 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREKK+ F+VA+K LFKSQI K E Q+ REIEIQ+HL H
Sbjct: 76 DFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHP 135
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAA---RYIYQVADAVEY 144
NILRL +F+D RRIYL++E+A G LYK L S F E + A + ++ADA+ Y
Sbjct: 136 NILRLYNYFYDRRRIYLILEYAPRGMLYKELQKS--CTFDEQRTATVRAVMEELADALMY 193
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVY 181
CH VIHRDIKPEN+L+ G+LK+ADF EMI+ ++
Sbjct: 194 CHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMH 253
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISKTYGW 241
+ VD WCIGVL YE LVG PPFE+ ++TY RI+ +D+ +P+ +P GA+DLISK
Sbjct: 254 NEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPTGAQDLISKLLR- 312
Query: 242 FHSAALSIPL 251
H+ + +PL
Sbjct: 313 -HNPSERLPL 321
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 217 bits (530), Expect = 3e-56
Identities = 107/233 (45%), Positives = 153/233 (65%), Gaps = 25/233 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+ K+ E Q+ RE+EIQSHL+H
Sbjct: 131 DFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHP 190
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NILRL +FHD R+YL++E+A G +Y+ L +F E + A ++A+A+ YCH
Sbjct: 191 NILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKFDEQRTANLYNRIANALSYCHS 248
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-----------------------EMIKREVYDVS 184
VIHRDIKPEN+L+ +G+LK+ADF EMI+ ++D
Sbjct: 249 KRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEK 308
Query: 185 VDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GVL YEFLVGKPPFE +TY RI ++ +P + +GA+DLIS+
Sbjct: 309 VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISR 361
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 208 bits (508), Expect = 1e-53
Identities = 107/233 (45%), Positives = 151/233 (64%), Gaps = 27/233 (11%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------- 173
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK+ADF
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRTT 288
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
EMI+ ++D VD W +GVL YEFLVGKPPFE +TY RI
Sbjct: 289 LCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
>AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein.
Length = 271
Score = 170 bits (414), Expect = 3e-42
Identities = 79/163 (48%), Positives = 117/163 (71%), Gaps = 4/163 (2%)
Query: 7 ELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIV 66
EL +K N ++ +W+ DFE+G LG+GKFG+V++AREK++ F++A+K LFK+Q+
Sbjct: 113 ELASKQKNEES--KKRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLE 170
Query: 67 KSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRF 126
K+ E Q+ RE+EIQSHL+H NILRL +FHD R+YL++E+A G +Y+ L +F
Sbjct: 171 KAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYREL--QKLSKF 228
Query: 127 PESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLK 169
E + A YI ++A+A+ YCH VIHRDIKPEN+L+ +G+LK
Sbjct: 229 DEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELK 271
>X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein.
Length = 358
Score = 142 bits (344), Expect = 1e-33
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 24/236 (10%)
Query: 24 WSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSH 83
+S +DF+ +++G G FG VH+ +EK A+K + +++ K E+ V E +
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103
Query: 84 LKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVE 143
+ H ++RL +HDER +Y+++E+ GGEL+ +L N +GRF + Y ++ A+E
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRN--RGRFSSTTGLFYSAEIICAIE 161
Query: 144 YCHQHHVIHRDIKPENILVAFSGDLKLADF----------------------EMIKREVY 181
Y H +++RD+KPENIL+ G +KL DF E+I+ + +
Sbjct: 162 YLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGH 221
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
+VD W +G+L++E L G PPF + Y +IL+ I +P H+ KDLI K
Sbjct: 222 GRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277
>BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linked
protein.
Length = 358
Score = 142 bits (344), Expect = 1e-33
Identities = 77/236 (32%), Positives = 128/236 (54%), Gaps = 24/236 (10%)
Query: 24 WSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSH 83
+S +DF+ +++G G FG VH+ +EK A+K + +++ K E+ V E +
Sbjct: 44 YSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNEKSVLKE 103
Query: 84 LKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVE 143
+ H ++RL +HDER +Y+++E+ GGEL+ +L N +GRF + Y ++ A+E
Sbjct: 104 VSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRN--RGRFSSTTGLFYSAEIICAIE 161
Query: 144 YCHQHHVIHRDIKPENILVAFSGDLKLADF----------------------EMIKREVY 181
Y H +++RD+KPENIL+ G +KL DF E+I+ + +
Sbjct: 162 YLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGH 221
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
+VD W +G+L++E L G PPF + Y +IL+ I +P H+ KDLI K
Sbjct: 222 GRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 130 bits (315), Expect = 3e-30
Identities = 82/233 (35%), Positives = 120/233 (51%), Gaps = 24/233 (10%)
Query: 25 SPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL 84
S FE +LG G FG V + R ++TG A+K L K ++VK K ++ E I +
Sbjct: 49 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 108
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+++L F D +YLV+E+ GGE++ L GRF E A Y QV AV+Y
Sbjct: 109 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQY 166
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YD 182
H +IHRD+KPEN+L+ G L++ DF KR E+ Y+
Sbjct: 167 LHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYN 226
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+VD W +GVL+YE VG PPF + + Y +I+S + +PS + KDL+
Sbjct: 227 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKDLL 279
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 130 bits (314), Expect = 5e-30
Identities = 73/233 (31%), Positives = 122/233 (52%), Gaps = 26/233 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF++G+ LG+G F V+ A TG VAIK + K + K+ ++V E++I LKH
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHP 70
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+IL L +F D +YLV+E GE+ ++L N + F E++A +++Q+ + Y H
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-PFSENEARHFMHQIITGMLYLHS 129
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKREVYD 182
H ++HRD+ N+L+ + ++K+ADF E+ R +
Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHG 189
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+ D W +G + Y L+G+PPF+T+ T +++ D PS + AKDLI
Sbjct: 190 LESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPSFLSIEAKDLI 242
>BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 129 bits (311), Expect = 1e-29
Identities = 77/236 (32%), Positives = 122/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 91
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A++Y
Sbjct: 92 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIDY 149
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 209
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 210 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 265
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 128 bits (310), Expect = 1e-29
Identities = 72/233 (30%), Positives = 122/233 (52%), Gaps = 26/233 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF++G+ LG+G F V+ A TG VAIK + K + K+ ++V E++I LKH
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHP 70
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+IL L +F D +YLV+E GE+ ++L N + F E++A +++Q+ + Y H
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-PFSENEARHFMHQIITGMLYLHS 129
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKREVYD 182
H ++HRD+ N+L+ + ++K+ADF E+ R +
Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHG 189
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+ D W +G + Y L+G+PPF+T+ T +++ D P+ + AKDLI
Sbjct: 190 LESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLI 242
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 90 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 149
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 150 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 207
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 208 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 267
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 268 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 317
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 90 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 149
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 150 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 207
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 208 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 267
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 268 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 317
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 128 bits (310), Expect = 1e-29
Identities = 78/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 69 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 128
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 129 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 186
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 187 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 246
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 247 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 296
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 2e-29
Identities = 81/233 (34%), Positives = 119/233 (51%), Gaps = 24/233 (10%)
Query: 25 SPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL 84
S FE +LG G FG V + R ++TG A+K L K ++VK K ++ E I +
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+++L F D +YLV+E+ GGE++ L GRF E A Y QV AV+Y
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQY 157
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YD 182
H +IHRD+KPEN+L+ G L++ DF KR E+ Y+
Sbjct: 158 LHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYN 217
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+VD W +GVL+YE VG PPF + + Y +I+S + +PS + K L+
Sbjct: 218 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLL 270
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 2e-29
Identities = 81/233 (34%), Positives = 119/233 (51%), Gaps = 24/233 (10%)
Query: 25 SPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL 84
S FE +LG G FG V + R ++TG A+K L K ++VK K ++ E I +
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+++L F D +YLV+E+ GGE++ L GRF E A Y QV AV+Y
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQY 157
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YD 182
H +IHRD+KPEN+L+ G L++ DF KR E+ Y+
Sbjct: 158 LHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYN 217
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+VD W +GVL+YE VG PPF + + Y +I+S + +PS + K L+
Sbjct: 218 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLL 270
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 128 bits (308), Expect = 2e-29
Identities = 81/233 (34%), Positives = 119/233 (51%), Gaps = 24/233 (10%)
Query: 25 SPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL 84
S FE +LG G FG V + R ++TG A+K L K ++VK K ++ E I +
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+++L F D +YLV+E+ GGE++ L GRF E A Y QV AV+Y
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQY 157
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YD 182
H +IHRD+KPEN+L+ G L++ DF KR E+ Y+
Sbjct: 158 LHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYN 217
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+VD W +GVL+YE VG PPF + + Y +I+S + +PS + K L+
Sbjct: 218 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLL 270
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 128 bits (308), Expect = 2e-29
Identities = 81/233 (34%), Positives = 119/233 (51%), Gaps = 24/233 (10%)
Query: 25 SPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL 84
S FE +LG G FG V + R ++TG A+K L K ++VK K ++ E I +
Sbjct: 40 SSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAI 99
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+++L F D +YLV+E+ GGE++ L GRF E A Y QV AV+Y
Sbjct: 100 DFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQR--VGRFSEPHACFYAAQVVLAVQY 157
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YD 182
H +IHRD+KPEN+L+ G L++ DF KR E+ Y+
Sbjct: 158 LHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYN 217
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+VD W +GVL+YE VG PPF + + Y +I+S + +PS + K L+
Sbjct: 218 KAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLL 270
>Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 91
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 92 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 149
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 209
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 210 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 265
>Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 427
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 92 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 151
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 152 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 209
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 210 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 269
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 270 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 325
>BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein.
Length = 367
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 91
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 92 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 149
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 209
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 210 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 265
>BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 367
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 91
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 92 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 149
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 209
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 210 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 265
>AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein.
Length = 427
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 92 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 151
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 152 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 209
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 210 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 269
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 270 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 325
>AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein.
Length = 367
Score = 127 bits (307), Expect = 3e-29
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 91
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 92 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 149
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 150 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 209
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 210 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 265
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 127 bits (307), Expect = 3e-29
Identities = 71/233 (30%), Positives = 122/233 (52%), Gaps = 26/233 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF++G+ LG+G F V+ A +G VAIK + K + K+ ++V E++I LKH
Sbjct: 11 DFKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHP 70
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+IL L +F D +YLV+E GE+ ++L N + F E++A +++Q+ + Y H
Sbjct: 71 SILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVK-PFSENEARHFMHQIITGMLYLHS 129
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKREVYD 182
H ++HRD+ N+L+ + ++K+ADF E+ R +
Sbjct: 130 HGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHG 189
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+ D W +G + Y L+G+PPF+T+ T +++ D P+ + AKDLI
Sbjct: 190 LESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVLADYEMPTFLSIEAKDLI 242
>Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 126 bits (305), Expect = 6e-29
Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 24/216 (11%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLL 93
++G G FG VH+ +EK A+K + +++ K E+ V E + + H ++RL
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
+H+ER +Y+++E+ GGEL+ +L N +G F + Y ++ A+EY H +++R
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRN--RGHFSSTTGLFYSAEIICAIEYLHSKEIVYR 171
Query: 154 DIKPENILVAFSGDLKLADF----------------------EMIKREVYDVSVDHWCIG 191
D+KPENIL+ G +KL DF E+I+ + + +VD W +G
Sbjct: 172 DLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 231
Query: 192 VLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
+L++E L G PPF + Y +IL+ + +P H+
Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein.
Length = 277
Score = 126 bits (305), Expect = 6e-29
Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 24/216 (11%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLL 93
++G G FG VH+ +EK A+K + +++ K E+ V E + + H ++RL
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
+H+ER +Y+++E+ GGEL+ +L N +G F + Y ++ A+EY H +++R
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRN--RGHFSSTTGLFYSAEIICAIEYLHSKEIVYR 171
Query: 154 DIKPENILVAFSGDLKLADF----------------------EMIKREVYDVSVDHWCIG 191
D+KPENIL+ G +KL DF E+I+ + + +VD W +G
Sbjct: 172 DLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 231
Query: 192 VLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
+L++E L G PPF + Y +IL+ + +P H+
Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 126 bits (305), Expect = 6e-29
Identities = 77/229 (33%), Positives = 116/229 (50%), Gaps = 24/229 (10%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G FG V + + K+TG A+K L K ++VK K + E I +
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+++L F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSVD 186
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +VD
Sbjct: 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 187 HWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (305), Expect = 6e-29
Identities = 77/229 (33%), Positives = 116/229 (50%), Gaps = 24/229 (10%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G FG V + + K+TG A+K L K ++VK K + E I +
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+++L F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSVD 186
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +VD
Sbjct: 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 187 HWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (305), Expect = 6e-29
Identities = 77/229 (33%), Positives = 116/229 (50%), Gaps = 24/229 (10%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G FG V + + K+TG A+K L K ++VK K + E I +
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+++L F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSVD 186
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +VD
Sbjct: 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 187 HWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 126 bits (305), Expect = 6e-29
Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 24/216 (11%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLL 93
++G G FG VH+ +EK A+K + +++ K E+ V E + + H ++RL
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
+H+ER +Y+++E+ GGEL+ +L N +G F + Y ++ A+EY H +++R
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRN--RGHFSSTTGLFYSAEIICAIEYLHSKEIVYR 171
Query: 154 DIKPENILVAFSGDLKLADF----------------------EMIKREVYDVSVDHWCIG 191
D+KPENIL+ G +KL DF E+I+ + + +VD W +G
Sbjct: 172 DLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 231
Query: 192 VLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
+L++E L G PPF + Y +IL+ + +P H+
Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linked
protein.
Length = 277
Score = 126 bits (305), Expect = 6e-29
Identities = 66/216 (30%), Positives = 115/216 (53%), Gaps = 24/216 (11%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLL 93
++G G FG VH+ +EK A+K + +++ K E+ V E + + H ++RL
Sbjct: 54 TMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNEKSVLKEVSHPFLIRLF 113
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
+H+ER +Y+++E+ GGEL+ +L N +G F + Y ++ A+EY H +++R
Sbjct: 114 WTWHEERFLYMLMEYVPGGELFSYLRN--RGHFSSTTGLFYSAEIICAIEYLHSKEIVYR 171
Query: 154 DIKPENILVAFSGDLKLADF----------------------EMIKREVYDVSVDHWCIG 191
D+KPENIL+ G +KL DF E+I+ + + +VD W +G
Sbjct: 172 DLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALG 231
Query: 192 VLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
+L++E L G PPF + Y +IL+ + +P H+
Sbjct: 232 ILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHL 267
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 126 bits (305), Expect = 6e-29
Identities = 77/229 (33%), Positives = 116/229 (50%), Gaps = 24/229 (10%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G FG V + + K+TG A+K L K ++VK K + E I +
Sbjct: 44 FERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPF 103
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+++L F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 104 LVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHSL 161
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSVD 186
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +VD
Sbjct: 162 DLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVD 221
Query: 187 HWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
W +GVL+YE G PPF + + Y +I+S + +PSH KDL+
Sbjct: 222 WWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 126 bits (305), Expect = 6e-29
Identities = 77/236 (32%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K + +M E + ++
Sbjct: 58 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNV 117
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F +Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 118 RHPFLVGLRYSFQTPEELYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 175
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 176 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 235
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 236 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 291
>Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 366
Score = 126 bits (303), Expect = 1e-28
Identities = 78/236 (33%), Positives = 121/236 (51%), Gaps = 29/236 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF+ +G+G +G V +A+ K G A+K L K I+K K E +M E + ++
Sbjct: 32 PTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKK-ESHIMAERSVLLKNV 90
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
+H ++ L F ++Y V+++ GGEL+ HL + RF E +A Y +VA A+ Y
Sbjct: 91 RHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQR--ERRFLEPRARFYAAEVASAIGY 148
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++I+RD+KPENIL+ G + L DF E++++E
Sbjct: 149 LHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKE 208
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF ++ + Y IL + P A DL+
Sbjct: 209 PYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLL 264
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 124 bits (298), Expect = 4e-28
Identities = 81/242 (33%), Positives = 124/242 (51%), Gaps = 28/242 (11%)
Query: 20 SSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIE 79
SS + +FE LG+G FG V +AR K+TG L A+K L K I++ M E
Sbjct: 346 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKR 405
Query: 80 IQSHLK-HSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
I S + H + +L F R++ V+EF GG+L H+ S RF E++A Y ++
Sbjct: 406 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSR--RFDEARARFYAAEI 463
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
A+ + H +I+RD+K +N+L+ G KLADF
Sbjct: 464 ISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAP 523
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E+++ +Y +VD W +GVLLYE L G PFE E ED + IL+ ++VYP+ + + A
Sbjct: 524 EILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATG 583
Query: 234 LI 235
++
Sbjct: 584 IL 585
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 124 bits (298), Expect = 4e-28
Identities = 76/230 (33%), Positives = 115/230 (50%), Gaps = 24/230 (10%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY +
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLNS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDIIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W +GVL+YE G PPF + + Y +I+S + +PS+ KDL+
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSNFSSDLKDLL 270
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 123 bits (296), Expect = 7e-28
Identities = 70/235 (29%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++L +LG+G F V +AR TG VA+K + K+++ + + +E+ ++H N
Sbjct: 17 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL + ++YL++E GG+++ ++ +G E A +Y Q+ A+ YCH+
Sbjct: 76 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKL 134
Query: 149 HVIHRDIKPENIL-VAFSGDLKLADF------------------------EMIKREVYDV 183
HV+HRD+KPEN++ G +KL DF E++ + YD
Sbjct: 135 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 194
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
+VD W +GV+L+ + G+PPF+ + +T I+ PSH+ KDLI++
Sbjct: 195 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITR 249
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 123 bits (296), Expect = 7e-28
Identities = 70/235 (29%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++L +LG+G F V +AR TG VA+K + K+++ + + +E+ ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL + ++YL++E GG+++ ++ +G E A +Y Q+ A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKL 133
Query: 149 HVIHRDIKPENIL-VAFSGDLKLADF------------------------EMIKREVYDV 183
HV+HRD+KPEN++ G +KL DF E++ + YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
+VD W +GV+L+ + G+PPF+ + +T I+ PSH+ KDLI++
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITR 248
>AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL
protein.
Length = 496
Score = 123 bits (296), Expect = 7e-28
Identities = 78/241 (32%), Positives = 123/241 (51%), Gaps = 29/241 (12%)
Query: 3 SEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFK 62
S+ L ++ IN G+ + P DF+ +G+G FG V +A+ K G + A+K L K
Sbjct: 137 SQKLHSTSQNINLGPSGNPHA-KPTDFDFLKVIGKGSFGKVLLAKRKLDGKVYAVKVLQK 195
Query: 63 SQIVKSKCERQVMREIEIQ-SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNS 121
++ K ++ +M E + ++KH ++ L F ++Y V++F GGEL+ HL
Sbjct: 196 KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQR- 254
Query: 122 PQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF-------- 173
+ FPE +A Y ++A A+ Y H +++RD+KPENILV G + L DF
Sbjct: 255 -ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILVDSVGHVVLTDFGLCKEGIA 313
Query: 174 -----------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
E+I+++ YD +VD WC+G +LYE L G PPF + Y I
Sbjct: 314 ISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNI 373
Query: 217 L 217
L
Sbjct: 374 L 374
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 190 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 249
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 250 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 307
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 308 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 368 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 155 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 212
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 273 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 122 bits (295), Expect = 9e-28
Identities = 79/244 (32%), Positives = 123/244 (50%), Gaps = 31/244 (12%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIKTLFKSQIVKS-KCERQVMREI 78
K P FEL LG+G +G V R+ TG + A+K L K+ IV++ K E
Sbjct: 62 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER 121
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
I +KH I+ L+ F ++YL++E+ +GGEL+ L +G F E A Y+ ++
Sbjct: 122 NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER--EGIFMEDTACFYLAEI 179
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH----------- 187
+ A+ + HQ +I+RD+KPENI++ G +KL DF + K ++D +V H
Sbjct: 180 SMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAP 239
Query: 188 --------------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
W +G L+Y+ L G PPF E KT +IL + P ++ A+D
Sbjct: 240 EILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARD 299
Query: 234 LISK 237
L+ K
Sbjct: 300 LLKK 303
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 122 bits (295), Expect = 9e-28
Identities = 79/244 (32%), Positives = 123/244 (50%), Gaps = 31/244 (12%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIKTLFKSQIVKS-KCERQVMREI 78
K P FEL LG+G +G V R+ TG + A+K L K+ IV++ K E
Sbjct: 85 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER 144
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
I +KH I+ L+ F ++YL++E+ +GGEL+ L +G F E A Y+ ++
Sbjct: 145 NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER--EGIFMEDTACFYLAEI 202
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH----------- 187
+ A+ + HQ +I+RD+KPENI++ G +KL DF + K ++D +V H
Sbjct: 203 SMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAP 262
Query: 188 --------------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
W +G L+Y+ L G PPF E KT +IL + P ++ A+D
Sbjct: 263 EILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARD 322
Query: 234 LISK 237
L+ K
Sbjct: 323 LLKK 326
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 122 bits (295), Expect = 9e-28
Identities = 81/242 (33%), Positives = 123/242 (50%), Gaps = 28/242 (11%)
Query: 20 SSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIE 79
SS + +FE LG+G FG V +AR K+TG L A+K L K I+ M E
Sbjct: 345 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILLDDDVECTMTEKR 404
Query: 80 IQSHLK-HSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
I S + H + +L F R++ V+EF GG+L H+ S RF E++A Y ++
Sbjct: 405 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSR--RFDEARARFYAAEI 462
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
A+ + H +I+RD+K +N+L+ G KLADF
Sbjct: 463 ISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAP 522
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E+++ +Y +VD W +GVLLYE L G PFE E ED + IL+ ++VYP+ + + A
Sbjct: 523 EILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATG 582
Query: 234 LI 235
++
Sbjct: 583 IL 584
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 122 bits (295), Expect = 9e-28
Identities = 79/244 (32%), Positives = 123/244 (50%), Gaps = 31/244 (12%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIKTLFKSQIVKS-KCERQVMREI 78
K P FEL LG+G +G V R+ TG + A+K L K+ IV++ K E
Sbjct: 85 KIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTKAER 144
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
I +KH I+ L+ F ++YL++E+ +GGEL+ L +G F E A Y+ ++
Sbjct: 145 NILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLER--EGIFMEDTACFYLAEI 202
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH----------- 187
+ A+ + HQ +I+RD+KPENI++ G +KL DF + K ++D +V H
Sbjct: 203 SMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEYMAP 262
Query: 188 --------------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
W +G L+Y+ L G PPF E KT +IL + P ++ A+D
Sbjct: 263 EILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQEARD 322
Query: 234 LISK 237
L+ K
Sbjct: 323 LLKK 326
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 155 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 212
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 273 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 190 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 249
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 250 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 307
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 308 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 368 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 190 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 249
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 250 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 307
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 308 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 367
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 368 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 423
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 109 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 168
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 169 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 226
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 227 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 286
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 287 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 342
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 155 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 212
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 273 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 85 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 144
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 145 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 202
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 203 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 262
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 263 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 318
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 155 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 212
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 273 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 122 bits (295), Expect = 9e-28
Identities = 75/236 (31%), Positives = 120/236 (50%), Gaps = 28/236 (11%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQ-SHL 84
P DF +G+G FG V +AR K A+K L K I+K K E+ +M E + ++
Sbjct: 95 PSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNV 154
Query: 85 KHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEY 144
KH ++ L F ++Y V+++ GGEL+ HL + F E +A Y ++A A+ Y
Sbjct: 155 KHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQR--ERCFLEPRARFYAAEIASALGY 212
Query: 145 CHQHHVIHRDIKPENILVAFSGDLKLADF-------------------------EMIKRE 179
H ++++RD+KPENIL+ G + L DF E++ ++
Sbjct: 213 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ 272
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
YD +VD WC+G +LYE L G PPF + + Y IL+ + +I + A+ L+
Sbjct: 273 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL 328
>CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein.
Length = 429
Score = 121 bits (292), Expect = 2e-27
Identities = 77/241 (31%), Positives = 122/241 (50%), Gaps = 29/241 (12%)
Query: 3 SEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFK 62
S+ L ++ IN G+ + P DF+ +G+G FG V +A+ K G A+K L K
Sbjct: 70 SQKLHSTSQNINLGPSGNPHA-KPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQK 128
Query: 63 SQIVKSKCERQVMREIEIQ-SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNS 121
++ K ++ +M E + ++KH ++ L F ++Y V++F GGEL+ HL
Sbjct: 129 KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQR- 187
Query: 122 PQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF-------- 173
+ FPE +A Y ++A A+ Y H +++RD+KPENIL+ G + L DF
Sbjct: 188 -ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIA 246
Query: 174 -----------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
E+I+++ YD +VD WC+G +LYE L G PPF + Y I
Sbjct: 247 ISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNI 306
Query: 217 L 217
L
Sbjct: 307 L 307
>BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase family, member 3 protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 77/241 (31%), Positives = 122/241 (50%), Gaps = 29/241 (12%)
Query: 3 SEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFK 62
S+ L ++ IN G+ + P DF+ +G+G FG V +A+ K G A+K L K
Sbjct: 137 SQKLHSTSQNINLGPSGNPHA-KPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQK 195
Query: 63 SQIVKSKCERQVMREIEIQ-SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNS 121
++ K ++ +M E + ++KH ++ L F ++Y V++F GGEL+ HL
Sbjct: 196 KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQR- 254
Query: 122 PQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF-------- 173
+ FPE +A Y ++A A+ Y H +++RD+KPENIL+ G + L DF
Sbjct: 255 -ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIA 313
Query: 174 -----------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
E+I+++ YD +VD WC+G +LYE L G PPF + Y I
Sbjct: 314 ISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNI 373
Query: 217 L 217
L
Sbjct: 374 L 374
>AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid
regulated kinase-like isoform 1 variant protein.
Length = 496
Score = 121 bits (292), Expect = 2e-27
Identities = 77/241 (31%), Positives = 122/241 (50%), Gaps = 29/241 (12%)
Query: 3 SEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFK 62
S+ L ++ IN G+ + P DF+ +G+G FG V +A+ K G A+K L K
Sbjct: 137 SQKLHSTSQNINLGPSGNPHA-KPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQK 195
Query: 63 SQIVKSKCERQVMREIEIQ-SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNS 121
++ K ++ +M E + ++KH ++ L F ++Y V++F GGEL+ HL
Sbjct: 196 KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQR- 254
Query: 122 PQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF-------- 173
+ FPE +A Y ++A A+ Y H +++RD+KPENIL+ G + L DF
Sbjct: 255 -ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIA 313
Query: 174 -----------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
E+I+++ YD +VD WC+G +LYE L G PPF + Y I
Sbjct: 314 ISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNI 373
Query: 217 L 217
L
Sbjct: 374 L 374
>AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein.
Length = 429
Score = 121 bits (292), Expect = 2e-27
Identities = 77/241 (31%), Positives = 122/241 (50%), Gaps = 29/241 (12%)
Query: 3 SEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFK 62
S+ L ++ IN G+ + P DF+ +G+G FG V +A+ K G A+K L K
Sbjct: 70 SQKLHSTSQNINLGPSGNPHA-KPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQK 128
Query: 63 SQIVKSKCERQVMREIEIQ-SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNS 121
++ K ++ +M E + ++KH ++ L F ++Y V++F GGEL+ HL
Sbjct: 129 KIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQR- 187
Query: 122 PQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF-------- 173
+ FPE +A Y ++A A+ Y H +++RD+KPENIL+ G + L DF
Sbjct: 188 -ERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIA 246
Query: 174 -----------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
E+I+++ YD +VD WC+G +LYE L G PPF + Y I
Sbjct: 247 ISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNI 306
Query: 217 L 217
L
Sbjct: 307 L 307
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 121 bits (291), Expect = 3e-27
Identities = 72/235 (30%), Positives = 124/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ + ++ + RE+ I L H
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHP 117
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 175
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 121 bits (291), Expect = 3e-27
Identities = 72/235 (30%), Positives = 124/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ + ++ + RE+ I L H
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHP 117
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 175
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 121 bits (291), Expect = 3e-27
Identities = 72/235 (30%), Positives = 124/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ + ++ + RE+ I L H
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHP 117
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 175
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 121 bits (291), Expect = 3e-27
Identities = 72/235 (30%), Positives = 124/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ + ++ + RE+ I L H
Sbjct: 59 NYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHP 117
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 175
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 77
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 135
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 136 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 195
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 196 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 250
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 77
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 135
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 136 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 195
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 196 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 250
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 110
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 168
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 42 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 100
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 101 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 158
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 159 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 218
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 219 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 273
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 19 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 77
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 78 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 135
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 136 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 195
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 196 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 250
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 120 bits (290), Expect = 4e-27
Identities = 73/235 (31%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VA+K + K+Q+ S ++ + RE+ I L H
Sbjct: 52 NYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHP 110
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 111 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLV--AHGRMKEKEARAKFRQIVSAVQYCHQ 168
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 169 KFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDG 228
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ K
Sbjct: 229 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 283
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 119 bits (286), Expect = 1e-26
Identities = 75/241 (31%), Positives = 121/241 (50%), Gaps = 31/241 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQ 81
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 64 PHSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 123
Query: 82 SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADA 141
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A
Sbjct: 124 ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLA 181
Query: 142 VEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH-------------- 187
+ + H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 182 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEIL 241
Query: 188 -----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+
Sbjct: 242 VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 301
Query: 237 K 237
K
Sbjct: 302 K 302
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 118 bits (285), Expect = 1e-26
Identities = 55/145 (37%), Positives = 94/145 (64%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V +AR + T VAIK + K+++ S E+ + RE+++ L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +Y+V EFA GE++ +LT++ G E++A + +Q+ AVEYCH H
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSN--GHLSENEARKKFWQILSAVEYCHDH 143
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
H++HRD+K EN+L+ + D+KLADF
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADF 168
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 118 bits (285), Expect = 1e-26
Identities = 55/145 (37%), Positives = 94/145 (64%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V +AR + T VAIK + K+++ S E+ + RE+++ L H +
Sbjct: 8 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 66
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +Y+V EFA GE++ +LT++ G E++A + +Q+ AVEYCH H
Sbjct: 67 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSN--GHLSENEARKKFWQILSAVEYCHDH 124
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
H++HRD+K EN+L+ + D+KLADF
Sbjct: 125 HIVHRDLKTENLLLDGNMDIKLADF 149
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 118 bits (285), Expect = 1e-26
Identities = 55/145 (37%), Positives = 94/145 (64%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V +AR + T VAIK + K+++ S E+ + RE+++ L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +Y+V EFA GE++ +LT++ G E++A + +Q+ AVEYCH H
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSN--GHLSENEARKKFWQILSAVEYCHDH 143
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
H++HRD+K EN+L+ + D+KLADF
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADF 168
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 118 bits (285), Expect = 1e-26
Identities = 75/240 (31%), Positives = 121/240 (50%), Gaps = 30/240 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK--TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQS 82
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 64 PHCFELLRVLGKGGYGKVFQVRKVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILE 123
Query: 83 HLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAV 142
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A+
Sbjct: 124 SVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLAL 181
Query: 143 EYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH--------------- 187
+ H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 182 GHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV 241
Query: 188 ----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+ K
Sbjct: 242 RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKK 301
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 118 bits (284), Expect = 2e-26
Identities = 71/235 (30%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ + ++ + RE+ I L H
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHP 113
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YL++E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLV--AHGRMKEKEARSKFRQIVSAVQYCHQ 171
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ +
Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 118 bits (284), Expect = 2e-26
Identities = 71/235 (30%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ + ++ + RE+ I L H
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHP 113
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YL++E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLV--AHGRMKEKEARSKFRQIVSAVQYCHQ 171
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ +
Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 118 bits (284), Expect = 2e-26
Identities = 71/235 (30%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ + ++ + RE+ I L H
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHP 113
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YL++E+A+GGE++ +L GR E +A Q+ AV+YCHQ
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGEVFDYLV--AHGRMKEKEARSKFRQIVSAVQYCHQ 171
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ +
Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 118 bits (283), Expect = 3e-26
Identities = 74/227 (32%), Positives = 118/227 (51%), Gaps = 31/227 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCE-RQVMREIEIQSHLKHSNILRLL 93
+G+G FG V+ R K + +VA+K F ++ +S+ E R + REIEI L+H NI+ +L
Sbjct: 10 IGEGSFGRVYKGRRKYSAQVVALK--FIPKLGRSEKELRNLQREIEIMRGLRHPNIVHML 67
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
F ++ + +V ++A G EL++ L + G+ PE + Q+ A+ Y H H ++HR
Sbjct: 68 DSFETDKEVVVVTDYAEG-ELFQILEDD--GKLPEDQVQAIAAQLVSALYYLHSHRILHR 124
Query: 154 DIKPENILVAFSGDLKLADF-------------------------EMIKREVYDVSVDHW 188
D+KP+NIL+A G +KL DF E+++ YD + D W
Sbjct: 125 DMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLW 184
Query: 189 CIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+G +LYE VG PPF + + IL + +PS I KD +
Sbjct: 185 SVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKDFL 231
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 118 bits (283), Expect = 3e-26
Identities = 75/241 (31%), Positives = 121/241 (50%), Gaps = 31/241 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQ 81
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 64 PHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 123
Query: 82 SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADA 141
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A
Sbjct: 124 ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLA 181
Query: 142 VEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH-------------- 187
+ + H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 182 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEIL 241
Query: 188 -----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+
Sbjct: 242 VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 301
Query: 237 K 237
K
Sbjct: 302 K 302
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 118 bits (283), Expect = 3e-26
Identities = 68/235 (28%), Positives = 121/235 (51%), Gaps = 28/235 (11%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++L +LG+G F V +AR TG VA+K + K+++ + + +E+ ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL + ++YL++E G+++ ++ +G E +Y Q+ A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEG-LNEDLPKKYFAQIVHAISYCHKL 133
Query: 149 HVIHRDIKPENIL-VAFSGDLKLADF------------------------EMIKREVYDV 183
HV+HRD+KPEN++ G +KL DF E++ + YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
+VD W +GV+L+ + G+PPF+ + +T I+ PSH+ KDLI++
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITR 248
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 118 bits (283), Expect = 3e-26
Identities = 75/241 (31%), Positives = 121/241 (50%), Gaps = 31/241 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQ 81
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 64 PHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 123
Query: 82 SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADA 141
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A
Sbjct: 124 ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLA 181
Query: 142 VEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH-------------- 187
+ + H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 182 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEIL 241
Query: 188 -----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+
Sbjct: 242 VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 301
Query: 237 K 237
K
Sbjct: 302 K 302
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 118 bits (283), Expect = 3e-26
Identities = 75/241 (31%), Positives = 121/241 (50%), Gaps = 31/241 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQ 81
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 64 PHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 123
Query: 82 SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADA 141
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A
Sbjct: 124 ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLA 181
Query: 142 VEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH-------------- 187
+ + H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 182 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEIL 241
Query: 188 -----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+
Sbjct: 242 VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 301
Query: 237 K 237
K
Sbjct: 302 K 302
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 118 bits (283), Expect = 3e-26
Identities = 75/241 (31%), Positives = 121/241 (50%), Gaps = 31/241 (12%)
Query: 26 PRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQIVKS-KCERQVMREIEIQ 81
P FEL LG+G +G V R+ + G + A+K L K++IV++ K E I
Sbjct: 77 PHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNIL 136
Query: 82 SHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADA 141
+KH I+ L F ++YL++E +GGEL+ HL +G F E A Y+ ++ A
Sbjct: 137 ESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLER--EGIFLEDTACFYLAEITLA 194
Query: 142 VEYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDVSVDH-------------- 187
+ + H +I+RD+KPENI+++ G +KL DF + K +++ +V H
Sbjct: 195 LGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEIL 254
Query: 188 -----------WCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
W +G L+Y+ L G PPF E KT +I+ + P ++ A+DL+
Sbjct: 255 VRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVK 314
Query: 237 K 237
K
Sbjct: 315 K 315
>X66357-1|CAA47001.1| 305|Homo sapiens serine/threonine protein
kinase protein.
Length = 305
Score = 117 bits (281), Expect = 5e-26
Identities = 56/149 (37%), Positives = 91/149 (61%), Gaps = 2/149 (1%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
F+ +G+G +G V+ A+ ++TG LVA+K + + + +REI + LKH N
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKI-RLDLEMEGVPSTAIREISLLKELKHPN 62
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RLL H+ER++YLV EF + +L K++ ++P P Y++Q+ V +CH H
Sbjct: 63 IVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIK 177
VIHRD+KP+N+L+ G +KLADF + +
Sbjct: 122 RVIHRDLKPQNLLINELGAIKLADFGLAR 150
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AY789470-1|AAV40830.1| 305|Homo sapiens cyclin-dependent kinase 3
protein.
Length = 305
Score = 117 bits (281), Expect = 5e-26
Identities = 56/149 (37%), Positives = 91/149 (61%), Gaps = 2/149 (1%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
F+ +G+G +G V+ A+ ++TG LVA+K + + + +REI + LKH N
Sbjct: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKI-RLDLEMEGVPSTAIREISLLKELKHPN 62
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RLL H+ER++YLV EF + +L K++ ++P P Y++Q+ V +CH H
Sbjct: 63 IVRLLDVVHNERKLYLVFEFLSQ-DLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
Query: 149 HVIHRDIKPENILVAFSGDLKLADFEMIK 177
VIHRD+KP+N+L+ G +KLADF + +
Sbjct: 122 RVIHRDLKPQNLLINELGAIKLADFGLAR 150
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 117 bits (281), Expect = 5e-26
Identities = 82/239 (34%), Positives = 119/239 (49%), Gaps = 37/239 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
FE +LG G F V +A EK TG L A+K + K + K K E + EI + +KH N
Sbjct: 23 FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKAL-KGK-ESSIENEIAVLRKIKHEN 80
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YLV++ +GGEL+ + +G + E A+ I QV DAV Y H+
Sbjct: 81 IVALEDIYESPNHLYLVMQLVSGGELFDRIVE--KGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF------------------------EMIKREV 180
++HRD+KPEN+L +S D + ++DF E++ ++
Sbjct: 139 GIVHRDLKPENLLY-YSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
Y +VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFI 256
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 116 bits (280), Expect = 6e-26
Identities = 70/215 (32%), Positives = 114/215 (53%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 116
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 174
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 269
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 116 bits (280), Expect = 6e-26
Identities = 70/215 (32%), Positives = 114/215 (53%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 116
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 174
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 269
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 116 bits (280), Expect = 6e-26
Identities = 70/215 (32%), Positives = 114/215 (53%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 58 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 116
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 174
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 269
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 116 bits (280), Expect = 6e-26
Identities = 70/235 (29%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ + ++ + RE+ I L H
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHP 113
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YL++E+A+GG+++ +L GR E +A Q+ AV+YCHQ
Sbjct: 114 NIVKLFEVIETEKTLYLIMEYASGGKVFDYLV--AHGRMKEKEARSKFRQIVSAVQYCHQ 171
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ +
Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 116 bits (280), Expect = 6e-26
Identities = 70/215 (32%), Positives = 114/215 (53%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 59 NYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 117
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 118 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 175
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 176 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 235
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 236 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 270
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 116 bits (279), Expect = 8e-26
Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +GVL+YE G PPF + + Y +I+S
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 116 bits (279), Expect = 8e-26
Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 49 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 108
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 109 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 166
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 167 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 226
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +GVL+YE G PPF + + Y +I+S
Sbjct: 227 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 259
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 116 bits (279), Expect = 8e-26
Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 31 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 90
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 91 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 148
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 149 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 208
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +GVL+YE G PPF + + Y +I+S
Sbjct: 209 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 241
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 116 bits (279), Expect = 8e-26
Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +GVL+YE G PPF + + Y +I+S
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 116 bits (279), Expect = 8e-26
Identities = 72/213 (33%), Positives = 106/213 (49%), Gaps = 24/213 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DFE +LG G FG V + + K T A+K L K ++VK K + E I +
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
++RL F D +Y+V+E+ GGE++ HL GRF E A Y Q+ EY H
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRI--GRFSEPHARFYAAQIVLTFEYLHS 160
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKR-----------------EV-----YDVSV 185
+I+RD+KPEN+L+ G +++ DF KR E+ Y+ +V
Sbjct: 161 LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +GVL+YE G PPF + + Y +I+S
Sbjct: 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 116 bits (278), Expect = 1e-25
Identities = 73/227 (32%), Positives = 118/227 (51%), Gaps = 31/227 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCE-RQVMREIEIQSHLKHSNILRLL 93
+G+G FG V+ R K + +VA+K F ++ +S+ E R + REIEI L+H NI+ +L
Sbjct: 10 IGEGSFGRVYKGRRKYSAQVVALK--FIPKLGRSEKELRNLQREIEIMRGLRHPNIVHML 67
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
F ++ + +V ++A G EL++ L + G+ PE + Q+ A+ Y H H ++HR
Sbjct: 68 DSFETDKEVVVVTDYAEG-ELFQILEDD--GKLPEDQVQAIAAQLVSALYYLHSHRILHR 124
Query: 154 DIKPENILVAFSGDLKLADF-------------------------EMIKREVYDVSVDHW 188
D+KP+NIL+A G +KL DF E+++ YD + D W
Sbjct: 125 DMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLW 184
Query: 189 CIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+G +LYE VG PPF + + IL + +PS I K+ +
Sbjct: 185 SVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFL 231
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 116 bits (278), Expect = 1e-25
Identities = 73/227 (32%), Positives = 118/227 (51%), Gaps = 31/227 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCE-RQVMREIEIQSHLKHSNILRLL 93
+G+G FG V+ R K + +VA+K F ++ +S+ E R + REIEI L+H NI+ +L
Sbjct: 27 IGEGSFGRVYKGRRKYSAQVVALK--FIPKLGRSEKELRNLQREIEIMRGLRHPNIVHML 84
Query: 94 TWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHR 153
F ++ + +V ++A G EL++ L + G+ PE + Q+ A+ Y H H ++HR
Sbjct: 85 DSFETDKEVVVVTDYAEG-ELFQILEDD--GKLPEDQVQAIAAQLVSALYYLHSHRILHR 141
Query: 154 DIKPENILVAFSGDLKLADF-------------------------EMIKREVYDVSVDHW 188
D+KP+NIL+A G +KL DF E+++ YD + D W
Sbjct: 142 DMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLW 201
Query: 189 CIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
+G +LYE VG PPF + + IL + +PS I K+ +
Sbjct: 202 SVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFL 248
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 115 bits (277), Expect = 1e-25
Identities = 69/235 (29%), Positives = 123/235 (52%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G F V +AR TG VAIK + K+Q+ + ++ + RE+ I L H
Sbjct: 55 NYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHP 113
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L ++ +YL++E+A+GG+++ +L GR E +A Q+ AV+YCHQ
Sbjct: 114 NIVKLFEVIETQKTLYLIMEYASGGKVFDYLV--AHGRMKEKEARSKFRQIVSAVQYCHQ 171
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 172 KRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG 231
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLISK 237
VD W +GV+LY + G PF+ + + R+L P ++ ++L+ +
Sbjct: 232 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKR 286
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 115 bits (276), Expect = 2e-25
Identities = 75/232 (32%), Positives = 122/232 (52%), Gaps = 28/232 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+EL +LG+G +G V A E+ +G +VAIK++ K +I + + REIEI S L H +
Sbjct: 92 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 151
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ + F ++ +I +++E+A+ GELY ++ S + R E + + Q+ AV YCH++
Sbjct: 152 IISIYEVFENKDKIVIIMEYASKGELYDYI--SERRRLSERETRHFFRQIVSAVHYCHKN 209
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+K ENIL+ + ++K+ADF E++ Y
Sbjct: 210 GVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGP 269
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
VD W +GVLLY + G PF+ +I S + P+ P A+ LI
Sbjct: 270 EVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQ-PSDARGLI 320
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 114 bits (275), Expect = 2e-25
Identities = 71/202 (35%), Positives = 111/202 (54%), Gaps = 28/202 (13%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+E +LG+G +G V ARE +G LVAIK++ K +I + + REIEI S L H +
Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ + F + +I +V+E+A+ G+LY +++ Q E +A + Q+ AV YCHQ+
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ--LSEREARHFFRQIVSAVHYCHQN 169
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
V+HRD+K ENIL+ +G++K+ADF E++ + Y
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGP 229
Query: 184 SVDHWCIGVLLYEFLVGKPPFE 205
VD W +GVLLY + G PF+
Sbjct: 230 EVDSWSLGVLLYILVHGTMPFD 251
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 114 bits (275), Expect = 2e-25
Identities = 54/146 (36%), Positives = 93/146 (63%), Gaps = 3/146 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V +AR + T VAIK + K+++ S E+ + RE+++ L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +Y+V EFA GE++ +LT++ G E++A + +Q+ AVEYCH H
Sbjct: 86 IIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSN--GHLSENEARKKFWQILSAVEYCHDH 143
Query: 149 HVIHRDIKPENILVAFSGDLKLADFE 174
H++HRD+K EN+L+ + D+KLA E
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLAGTE 169
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 114 bits (275), Expect = 2e-25
Identities = 71/202 (35%), Positives = 111/202 (54%), Gaps = 28/202 (13%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+E +LG+G +G V ARE +G LVAIK++ K +I + + REIEI S L H +
Sbjct: 53 YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ + F + +I +V+E+A+ G+LY +++ Q E +A + Q+ AV YCHQ+
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQ--LSEREARHFFRQIVSAVHYCHQN 169
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
V+HRD+K ENIL+ +G++K+ADF E++ + Y
Sbjct: 170 RVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGP 229
Query: 184 SVDHWCIGVLLYEFLVGKPPFE 205
VD W +GVLLY + G PF+
Sbjct: 230 EVDSWSLGVLLYILVHGTMPFD 251
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 113 bits (273), Expect = 4e-25
Identities = 72/215 (33%), Positives = 113/215 (52%), Gaps = 28/215 (13%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+E+ ++G+G F V A T VAIK + K+Q+ + ++ + RE++I L H +
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKK-IFREVQIMKMLCHPH 66
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL ER IYLV E+A+GGE++ HL GR E +A R Q+ AV +CH
Sbjct: 67 IIRLYQVMETERMIYLVTEYASGGEIFDHLV--AHGRMAEKEARRKFKQIVTAVYFCHCR 124
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+++HRD+K EN+L+ + ++K+ADF E+ + + YD
Sbjct: 125 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 184
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
VD W +GV+LY + G PF+ AR+LS
Sbjct: 185 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLS 219
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 113 bits (273), Expect = 4e-25
Identities = 66/231 (28%), Positives = 118/231 (51%), Gaps = 28/231 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++L +LG+G F V +AR TG VA+K + K+++ + + +E+ ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL + ++YL++E GG+++ ++ +G E A +Y Q+ A+ YCH+
Sbjct: 75 IVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEG-LNEDLAKKYFAQIVHAISYCHKL 133
Query: 149 HVIHRDIKPENIL-VAFSGDLKLADF------------------------EMIKREVYDV 183
HV+HRD+KPEN++ G +KL DF E++ + YD
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
+VD W +GV+L+ + +PPF+ + +T I+ PSH+ K+
Sbjct: 194 PAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSHVSKECKE 244
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 113 bits (273), Expect = 4e-25
Identities = 72/215 (33%), Positives = 113/215 (52%), Gaps = 28/215 (13%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+E+ ++G+G F V A T VAIK + K+Q+ + ++ + RE++I L H +
Sbjct: 116 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKK-IFREVQIMKMLCHPH 174
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+RL ER IYLV E+A+GGE++ HL GR E +A R Q+ AV +CH
Sbjct: 175 IIRLYQVMETERMIYLVTEYASGGEIFDHLV--AHGRMAEKEARRKFKQIVTAVYFCHCR 232
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+++HRD+K EN+L+ + ++K+ADF E+ + + YD
Sbjct: 233 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 292
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
VD W +GV+LY + G PF+ AR+LS
Sbjct: 293 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLS 327
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 113 bits (272), Expect = 6e-25
Identities = 69/215 (32%), Positives = 113/215 (52%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 58 NYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 116
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 174
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 269
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 113 bits (272), Expect = 6e-25
Identities = 69/215 (32%), Positives = 113/215 (52%), Gaps = 28/215 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
++ L ++G+G V +AR TG VAIK + K+Q+ S ++ + RE+ I L H
Sbjct: 58 NYRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHP 116
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++L E+ +YLV+E+A+ GE++ +L + GR E +A Q+ AV YCHQ
Sbjct: 117 NIVKLFEVIETEKTLYLVMEYASAGEVFDYLVS--HGRMKEKEARAKFRQIVSAVHYCHQ 174
Query: 148 HHVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD- 182
+++HRD+K EN+L+ ++K+ADF E+ + + YD
Sbjct: 175 KNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDG 234
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL 217
VD W +GV+LY + G PF+ + R+L
Sbjct: 235 PEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVL 269
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 337 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 394
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 395 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 452
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 453 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 512
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 513 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 572
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 573 GIDMIEFPKKIAKNAANLIKK 593
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 337 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 394
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 395 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 452
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 453 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 512
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 513 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 572
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 573 GIDMIEFPKKIAKNAANLIKK 593
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 325 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 382
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 383 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 440
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 441 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 500
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 501 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 560
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 561 GIDMIEFPKKIAKNAANLIKK 581
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 325 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 382
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 383 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 440
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 441 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 500
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 501 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 560
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 561 GIDMIEFPKKIAKNAANLIKK 581
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 325 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 382
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 383 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 440
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 441 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 500
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 501 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 560
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 561 GIDMIEFPKKIAKNAANLIKK 581
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 352 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 409
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 410 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 467
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 468 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 527
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 528 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 587
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 588 GIDMIEFPKKIAKNAANLIKK 608
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 113 bits (271), Expect = 7e-25
Identities = 82/261 (31%), Positives = 127/261 (48%), Gaps = 31/261 (11%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREK-KTGFLVAIKTLFK 62
E E + K A+ ++ K S DF + +LG G FG V + + K + A+K L K
Sbjct: 325 EDAEAKAKYEAEAAFFANLKLS--DFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKK 382
Query: 63 SQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSP 122
IV ++ + + E +I I+RL F D + +Y+++E GGEL+ L +
Sbjct: 383 RHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRD-- 440
Query: 123 QGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------- 173
+G F +S Y V +A Y H +I+RD+KPEN+++ G KL DF
Sbjct: 441 RGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFG 500
Query: 174 ---------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL- 217
E+I + +D+S D+W +G+L+YE L G PPF KTY IL
Sbjct: 501 KKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILR 560
Query: 218 SLDIV-YPSHIPDGAKDLISK 237
+D++ +P I A +LI K
Sbjct: 561 GIDMIEFPKKIAKNAANLIKK 581
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 112 bits (269), Expect = 1e-24
Identities = 79/238 (33%), Positives = 121/238 (50%), Gaps = 35/238 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++ LG G F V +A +K+T LVAIK + K + ++ K E + EI + +KH N
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-EALEGK-EGSMENEIAVLHKIKHPN 77
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YL+++ +GGEL+ + +G + E A+R I+QV DAV+Y H
Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVE--KGFYTERDASRLIFQVLDAVKYLHDL 135
Query: 149 HVIHRDIKPENIL-VAFSGDLK--LADF------------------------EMIKREVY 181
++HRD+KPEN+L + D K ++DF E++ ++ Y
Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
+VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 112 bits (269), Expect = 1e-24
Identities = 79/238 (33%), Positives = 121/238 (50%), Gaps = 35/238 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++ LG G F V +A +K+T LVAIK + K + ++ K E + EI + +KH N
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-EALEGK-EGSMENEIAVLHKIKHPN 77
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YL+++ +GGEL+ + +G + E A+R I+QV DAV+Y H
Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVE--KGFYTERDASRLIFQVLDAVKYLHDL 135
Query: 149 HVIHRDIKPENIL-VAFSGDLK--LADF------------------------EMIKREVY 181
++HRD+KPEN+L + D K ++DF E++ ++ Y
Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
+VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 112 bits (269), Expect = 1e-24
Identities = 79/238 (33%), Positives = 121/238 (50%), Gaps = 35/238 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
++ LG G F V +A +K+T LVAIK + K + ++ K E + EI + +KH N
Sbjct: 20 YDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAK-EALEGK-EGSMENEIAVLHKIKHPN 77
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L + +YL+++ +GGEL+ + +G + E A+R I+QV DAV+Y H
Sbjct: 78 IVALDDIYESGGHLYLIMQLVSGGELFDRIVE--KGFYTERDASRLIFQVLDAVKYLHDL 135
Query: 149 HVIHRDIKPENIL-VAFSGDLK--LADF------------------------EMIKREVY 181
++HRD+KPEN+L + D K ++DF E++ ++ Y
Sbjct: 136 GIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPY 195
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL----SLDIVYPSHIPDGAKDLI 235
+VD W IGV+ Y L G PPF E + K + +IL D Y I D AKD I
Sbjct: 196 SKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFI 253
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 111 bits (267), Expect = 2e-24
Identities = 68/213 (31%), Positives = 107/213 (50%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V++ + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 110 bits (265), Expect = 4e-24
Identities = 68/213 (31%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V + + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 110 bits (265), Expect = 4e-24
Identities = 68/213 (31%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V + + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 110 bits (265), Expect = 4e-24
Identities = 68/213 (31%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V + + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 110 bits (265), Expect = 4e-24
Identities = 68/213 (31%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V + + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 110 bits (265), Expect = 4e-24
Identities = 68/213 (31%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ LG +LG G FG V + + TG VA+K L + +I ++ REI+ +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L ++V+E+ +GGEL+ ++ GR E +A R Q+ AV+YCH+H
Sbjct: 76 IIKLYQVISTPTDFFMVMEYVSGGELFDYICK--HGRVEEMEARRLFQQILSAVDYCHRH 133
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DV 183
V+HRD+KPEN+L+ + K+ADF E+I +Y
Sbjct: 134 MVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGP 193
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
VD W GV+LY L G PF+ E + +I
Sbjct: 194 EVDIWSCGVILYALLCGTLPFDDEHVPTLFKKI 226
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 109 bits (263), Expect = 7e-24
Identities = 72/239 (30%), Positives = 116/239 (48%), Gaps = 27/239 (11%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQS 82
K + DF+ LG+G FG V + REK TG A+K L K I+ + E +
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 83 HLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAV 142
+ +H + L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A+
Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHL--SRERVFTEERARFYGAEIVSAL 263
Query: 143 EYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREV---------------------- 180
EY H V++RDIK EN+++ G +K+ DF + K +
Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLE 323
Query: 181 ---YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
Y +VD W +GV++YE + G+ PF + ++ + IL +I +P + AK L++
Sbjct: 324 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLA 382
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 109 bits (263), Expect = 7e-24
Identities = 72/239 (30%), Positives = 116/239 (48%), Gaps = 27/239 (11%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQS 82
K + DF+ LG+G FG V + REK TG A+K L K I+ + E +
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 83 HLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAV 142
+ +H + L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A+
Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHL--SRERVFTEERARFYGAEIVSAL 263
Query: 143 EYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREV---------------------- 180
EY H V++RDIK EN+++ G +K+ DF + K +
Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLE 323
Query: 181 ---YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
Y +VD W +GV++YE + G+ PF + ++ + IL +I +P + AK L++
Sbjct: 324 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLA 382
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 109 bits (263), Expect = 7e-24
Identities = 72/239 (30%), Positives = 116/239 (48%), Gaps = 27/239 (11%)
Query: 23 KWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQS 82
K + DF+ LG+G FG V + REK TG A+K L K I+ + E +
Sbjct: 146 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQ 205
Query: 83 HLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAV 142
+ +H + L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A+
Sbjct: 206 NTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHL--SRERVFTEERARFYGAEIVSAL 263
Query: 143 EYCHQHHVIHRDIKPENILVAFSGDLKLADFEMIKREV---------------------- 180
EY H V++RDIK EN+++ G +K+ DF + K +
Sbjct: 264 EYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLE 323
Query: 181 ---YDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
Y +VD W +GV++YE + G+ PF + ++ + IL +I +P + AK L++
Sbjct: 324 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLA 382
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 109 bits (263), Expect = 7e-24
Identities = 67/211 (31%), Positives = 107/211 (50%), Gaps = 27/211 (12%)
Query: 31 LGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNIL 90
LG +LG G FG V V + + TG VA+K L + +I ++ REI+ +H +I+
Sbjct: 20 LGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHII 79
Query: 91 RLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHV 150
+L I++V+E+ +GGEL+ ++ + GR E ++ R Q+ V+YCH+H V
Sbjct: 80 KLYQVISTPSDIFMVMEYVSGGELFDYICKN--GRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 151 IHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DVSV 185
+HRD+KPEN+L+ + K+ADF E+I +Y V
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV 197
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
D W GV+LY L G PF+ + + +I
Sbjct: 198 DIWSSGVILYALLCGTLPFDDDHVPTLFKKI 228
>AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 433
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 83 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 140
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 141 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 198
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 199 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 258
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 259 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 318
>AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 729
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM
kinase-like 1 protein.
Length = 740
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 390 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 447
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 448 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 505
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 565
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 566 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 625
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 109 bits (263), Expect = 7e-24
Identities = 67/211 (31%), Positives = 107/211 (50%), Gaps = 27/211 (12%)
Query: 31 LGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNIL 90
LG +LG G FG V V + + TG VA+K L + +I ++ REI+ +H +I+
Sbjct: 20 LGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHII 79
Query: 91 RLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHV 150
+L I++V+E+ +GGEL+ ++ + GR E ++ R Q+ V+YCH+H V
Sbjct: 80 KLYQVISTPSDIFMVMEYVSGGELFDYICKN--GRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 151 IHRDIKPENILVAFSGDLKLADF------------------------EMIKREVY-DVSV 185
+HRD+KPEN+L+ + K+ADF E+I +Y V
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV 197
Query: 186 DHWCIGVLLYEFLVGKPPFETEGEDKTYARI 216
D W GV+LY L G PF+ + + +I
Sbjct: 198 DIWSSGVILYALLCGTLPFDDDHVPTLFKKI 228
>AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein.
Length = 794
Score = 109 bits (263), Expect = 7e-24
Identities = 76/240 (31%), Positives = 122/240 (50%), Gaps = 36/240 (15%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G ++G G F V E+ T A+K + KS+ + K E + E+ I +KH N
Sbjct: 455 YKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKC-RGK-EHMIQNEVSILRRVKHPN 512
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ +YLV+E GG+L+ +T++ ++ E A+ +Y +A A++Y H
Sbjct: 513 IVLLIEEMDVPTELYLVMELVKGGDLFDAITST--NKYTERDASGMLYNLASAIKYLHSL 570
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
+++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 571 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYG 630
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEGEDK--TYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF G+D+ + +IL + +PS ++ D AK+LI+
Sbjct: 631 LKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELIT 690
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 109 bits (262), Expect = 9e-24
Identities = 79/260 (30%), Positives = 129/260 (49%), Gaps = 33/260 (12%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKS 63
E+++L+ K+ + SS + ++ E+ ++LG G FG V + + K A+K + K
Sbjct: 433 EMIQLKEKVAR---FSSSSPF--QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKK 487
Query: 64 QIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQ 123
IV +K + V E I L I++L F D + +Y+++E GGEL+ L + +
Sbjct: 488 HIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRD--R 545
Query: 124 GRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF---------- 173
G F E + + V +A +Y H+ +I+RD+KPEN+++ G LKL DF
Sbjct: 546 GSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQ 605
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS- 218
E+I + +D SVD W +G+L+YE L G PPF + TY IL
Sbjct: 606 KTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKG 665
Query: 219 -LDIVYPSHIPDGAKDLISK 237
+ +P I +DLI +
Sbjct: 666 IEKMDFPRKITRRPEDLIRR 685
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 109 bits (262), Expect = 9e-24
Identities = 79/260 (30%), Positives = 129/260 (49%), Gaps = 33/260 (12%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKS 63
E+++L+ K+ + SS + ++ E+ ++LG G FG V + + K A+K + K
Sbjct: 433 EMIQLKEKVAR---FSSSSPF--QNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKK 487
Query: 64 QIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQ 123
IV +K + V E I L I++L F D + +Y+++E GGEL+ L + +
Sbjct: 488 HIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRD--R 545
Query: 124 GRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF---------- 173
G F E + + V +A +Y H+ +I+RD+KPEN+++ G LKL DF
Sbjct: 546 GSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQ 605
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS- 218
E+I + +D SVD W +G+L+YE L G PPF + TY IL
Sbjct: 606 KTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKG 665
Query: 219 -LDIVYPSHIPDGAKDLISK 237
+ +P I +DLI +
Sbjct: 666 IEKMDFPRKITRRPEDLIRR 685
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 109 bits (262), Expect = 9e-24
Identities = 54/145 (37%), Positives = 89/145 (61%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V + R + T VAIK + KSQ+ E+ + RE++I L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 78
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +YLV E+A GE++ +L N GR ES+A R +Q+ AV+YCH
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLAN--HGRLNESEARRKFWQILSAVDYCHGR 136
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
++HRD+K EN+L+ + ++K+ADF
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADF 161
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 109 bits (262), Expect = 9e-24
Identities = 54/145 (37%), Positives = 89/145 (61%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V + R + T VAIK + KSQ+ E+ + RE++I L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 78
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +YLV E+A GE++ +L N GR ES+A R +Q+ AV+YCH
Sbjct: 79 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLAN--HGRLNESEARRKFWQILSAVDYCHGR 136
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
++HRD+K EN+L+ + ++K+ADF
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADF 161
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 109 bits (262), Expect = 9e-24
Identities = 54/145 (37%), Positives = 89/145 (61%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V + R + T VAIK + KSQ+ E+ + RE++I L H +
Sbjct: 18 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 76
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +YLV E+A GE++ +L N GR ES+A R +Q+ AV+YCH
Sbjct: 77 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLAN--HGRLNESEARRKFWQILSAVDYCHGR 134
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
++HRD+K EN+L+ + ++K+ADF
Sbjct: 135 KIVHRDLKAENLLLDNNMNIKIADF 159
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 109 bits (262), Expect = 9e-24
Identities = 54/145 (37%), Positives = 89/145 (61%), Gaps = 3/145 (2%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++ +LG+G F V + R + T VAIK + KSQ+ E+ + RE++I L H +
Sbjct: 44 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 102
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I++L + +YLV E+A GE++ +L N GR ES+A R +Q+ AV+YCH
Sbjct: 103 IIKLYQVMETKSMLYLVTEYAKNGEIFDYLAN--HGRLNESEARRKFWQILSAVDYCHGR 160
Query: 149 HVIHRDIKPENILVAFSGDLKLADF 173
++HRD+K EN+L+ + ++K+ADF
Sbjct: 161 KIVHRDLKAENLLLDNNMNIKIADF 185
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 108 bits (260), Expect = 2e-23
Identities = 81/243 (33%), Positives = 120/243 (49%), Gaps = 36/243 (14%)
Query: 27 RDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKH 86
+ +E G +G G F V R ++T A+K + KS++ K K E V EI I L H
Sbjct: 314 KHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRL-KGK-EDMVDSEILIIQSLSH 371
Query: 87 SNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH 146
NI++L + + IYL++E+ GG+L+ + S +FPE AA I + A+ + H
Sbjct: 372 PNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESV--KFPEPDAALMIMDLCKALVHMH 429
Query: 147 QHHVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREV 180
++HRD+KPEN+LV + D LKLADF E++ +
Sbjct: 430 DKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSEKG 489
Query: 181 YDVSVDHWCIGVLLYEFLVGKPPFET-EGEDKTYARILSLDIV-----YPSHIPDGAKDL 234
Y + VD W GV+LY L G PPF + E + I+ L Y +I D AKDL
Sbjct: 490 YGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDL 549
Query: 235 ISK 237
+S+
Sbjct: 550 VSR 552
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 108 bits (259), Expect = 2e-23
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 43 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 102
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 103 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 154
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 155 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 214
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T A IL
Sbjct: 215 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 275 KLGMPQFLSGEAQSLL 290
Score = 73.7 bits (173), Expect = 6e-13
Identities = 73/247 (29%), Positives = 105/247 (42%), Gaps = 48/247 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 525
Query: 148 HHVIHRDIKPENILVA-FSG---DLKLADFEMIK-------------------------R 178
V+HRD+KP NIL SG +++ DF K R
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 585
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +G+LLY L G PF G D T IL +L I D
Sbjct: 586 QGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDSISDA 644
Query: 231 AKDLISK 237
AKD++SK
Sbjct: 645 AKDVVSK 651
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 108 bits (259), Expect = 2e-23
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 43 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 102
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 103 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 154
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 155 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 214
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T A IL
Sbjct: 215 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 275 KLGMPQFLSGEAQSLL 290
Score = 73.7 bits (173), Expect = 6e-13
Identities = 73/247 (29%), Positives = 105/247 (42%), Gaps = 48/247 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 525
Query: 148 HHVIHRDIKPENILVA-FSG---DLKLADFEMIK-------------------------R 178
V+HRD+KP NIL SG +++ DF K R
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 585
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +G+LLY L G PF G D T IL +L I D
Sbjct: 586 QGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDSISDA 644
Query: 231 AKDLISK 237
AKD++SK
Sbjct: 645 AKDVVSK 651
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 108 bits (259), Expect = 2e-23
Identities = 71/226 (31%), Positives = 112/226 (49%), Gaps = 28/226 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KH 86
DF LG+G FG V +A K T L AIK L K +++ M E + + L K
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 87 SNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH 146
+ +L + F R+Y V+E+ GG+L H+ G+F E +A Y +++ + + H
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQV--GKFKEPQAVFYAAEISIGLFFLH 455
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +I+RD+K +N+++ G +K+ADF M K + Y
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
SVD W GVLLYE L G+PPF+ E ED+ + I+ ++ YP +
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL 561
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 108 bits (259), Expect = 2e-23
Identities = 79/262 (30%), Positives = 127/262 (48%), Gaps = 32/262 (12%)
Query: 2 KSEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIK 58
K E + E I +H GS K P FEL LGQG FG V + R+ +G L A+K
Sbjct: 36 KDEGVLKEISITHHVKAGSE-KADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMK 94
Query: 59 TLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHL 118
L K+ + K + + E +I + + H +++L F E ++YL+++F GG+L+ L
Sbjct: 95 VLKKATL-KVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153
Query: 119 TNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----- 173
S + F E Y+ ++A +++ H +I+RD+KPENIL+ G +KL DF
Sbjct: 154 --SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE 211
Query: 174 --------------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTY 213
E++ R+ + S D W GVL++E L G PF+ + +T
Sbjct: 212 AIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETM 271
Query: 214 ARILSLDIVYPSHIPDGAKDLI 235
IL + P + A+ L+
Sbjct: 272 TLILKAKLGMPQFLSTEAQSLL 293
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/215 (31%), Positives = 96/215 (44%), Gaps = 40/215 (18%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHSNILRL 92
++G G + K T A+K + KS+ R EIEI +H NI+ L
Sbjct: 423 TIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHPNIITL 475
Query: 93 LTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIH 152
+ D + +YLV E GGEL + Q F E +A+ ++ + VEY H V+H
Sbjct: 476 KDVYDDGKHVYLVTELMRGGELLDKILR--QKFFSEREASFVLHTIGKTVEYLHSQGVVH 533
Query: 153 RDIKPENIL-VAFSGD---LKLADF-------------------------EMIKREVYDV 183
RD+KP NIL V SG+ L++ DF E++KR+ YD
Sbjct: 534 RDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDE 593
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +G+LLY L G PF G T IL+
Sbjct: 594 GCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILT 627
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 108 bits (259), Expect = 2e-23
Identities = 71/226 (31%), Positives = 112/226 (49%), Gaps = 28/226 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KH 86
DF LG+G FG V +A K T L AIK L K +++ M E + + L K
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 87 SNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH 146
+ +L + F R+Y V+E+ GG+L H+ G+F E +A Y +++ + + H
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQV--GKFKEPQAVFYAAEISIGLFFLH 455
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +I+RD+K +N+++ G +K+ADF M K + Y
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
SVD W GVLLYE L G+PPF+ E ED+ + I+ ++ YP +
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL 561
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 108 bits (259), Expect = 2e-23
Identities = 71/226 (31%), Positives = 112/226 (49%), Gaps = 28/226 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KH 86
DF LG+G FG V +A K T L AIK L K +++ M E + + L K
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 87 SNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH 146
+ +L + F R+Y V+E+ GG+L H+ G+F E +A Y +++ + + H
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQV--GKFKEPQAVFYAAEISIGLFFLH 455
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +I+RD+K +N+++ G +K+ADF M K + Y
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
SVD W GVLLYE L G+PPF+ E ED+ + I+ ++ YP +
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL 561
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 108 bits (259), Expect = 2e-23
Identities = 79/262 (30%), Positives = 127/262 (48%), Gaps = 32/262 (12%)
Query: 2 KSEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIK 58
K E + E I +H GS K P FEL LGQG FG V + R+ +G L A+K
Sbjct: 36 KDEGVLKEISITHHVKAGSE-KADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMK 94
Query: 59 TLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHL 118
L K+ + K + + E +I + + H +++L F E ++YL+++F GG+L+ L
Sbjct: 95 VLKKATL-KVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153
Query: 119 TNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----- 173
S + F E Y+ ++A +++ H +I+RD+KPENIL+ G +KL DF
Sbjct: 154 --SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE 211
Query: 174 --------------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTY 213
E++ R+ + S D W GVL++E L G PF+ + +T
Sbjct: 212 AIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETM 271
Query: 214 ARILSLDIVYPSHIPDGAKDLI 235
IL + P + A+ L+
Sbjct: 272 TLILKAKLGMPQFLSTEAQSLL 293
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/215 (31%), Positives = 96/215 (44%), Gaps = 40/215 (18%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHSNILRL 92
++G G + K T A+K + KS+ R EIEI +H NI+ L
Sbjct: 423 TIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHPNIITL 475
Query: 93 LTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIH 152
+ D + +YLV E GGEL + Q F E +A+ ++ + VEY H V+H
Sbjct: 476 KDVYDDGKHVYLVTELMRGGELLDKILR--QKFFSEREASFVLHTIGKTVEYLHSQGVVH 533
Query: 153 RDIKPENIL-VAFSGD---LKLADF-------------------------EMIKREVYDV 183
RD+KP NIL V SG+ L++ DF E++KR+ YD
Sbjct: 534 RDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDE 593
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +G+LLY L G PF G T IL+
Sbjct: 594 GCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILT 627
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 108 bits (259), Expect = 2e-23
Identities = 52/143 (36%), Positives = 85/143 (59%), Gaps = 2/143 (1%)
Query: 31 LGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNIL 90
LG +LG G FG V V + + TG VA+K L + +I ++ REI+ +H +I+
Sbjct: 20 LGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHII 79
Query: 91 RLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHV 150
+L I++V+E+ +GGEL+ ++ + GR E ++ R Q+ V+YCH+H V
Sbjct: 80 KLYQVISTPSDIFMVMEYVSGGELFDYICKN--GRLDEKESRRLFQQILSGVDYCHRHMV 137
Query: 151 IHRDIKPENILVAFSGDLKLADF 173
+HRD+KPEN+L+ + K+ADF
Sbjct: 138 VHRDLKPENVLLDAHMNAKIADF 160
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 108 bits (259), Expect = 2e-23
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 43 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 102
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 103 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 154
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 155 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 214
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T A IL
Sbjct: 215 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 275 KLGMPQFLSGEAQSLL 290
Score = 73.7 bits (173), Expect = 6e-13
Identities = 73/247 (29%), Positives = 105/247 (42%), Gaps = 48/247 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 525
Query: 148 HHVIHRDIKPENILVA-FSG---DLKLADFEMIK-------------------------R 178
V+HRD+KP NIL SG +++ DF K R
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 585
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +G+LLY L G PF G D T IL +L I D
Sbjct: 586 QGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDSISDA 644
Query: 231 AKDLISK 237
AKD++SK
Sbjct: 645 AKDVVSK 651
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 108 bits (259), Expect = 2e-23
Identities = 71/226 (31%), Positives = 112/226 (49%), Gaps = 28/226 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KH 86
DF LG+G FG V +A K T L AIK L K +++ M E + + L K
Sbjct: 338 DFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKP 397
Query: 87 SNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH 146
+ +L + F R+Y V+E+ GG+L H+ G+F E +A Y +++ + + H
Sbjct: 398 PFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQV--GKFKEPQAVFYAAEISIGLFFLH 455
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +I+RD+K +N+++ G +K+ADF M K + Y
Sbjct: 456 KRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPY 515
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHI 227
SVD W GVLLYE L G+PPF+ E ED+ + I+ ++ YP +
Sbjct: 516 GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSL 561
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 108 bits (259), Expect = 2e-23
Identities = 79/262 (30%), Positives = 127/262 (48%), Gaps = 32/262 (12%)
Query: 2 KSEVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVARE---KKTGFLVAIK 58
K E + E I +H GS K P FEL LGQG FG V + R+ +G L A+K
Sbjct: 36 KDEGVLKEISITHHVKAGSE-KADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMK 94
Query: 59 TLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHL 118
L K+ + K + + E +I + + H +++L F E ++YL+++F GG+L+ L
Sbjct: 95 VLKKATL-KVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRL 153
Query: 119 TNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----- 173
S + F E Y+ ++A +++ H +I+RD+KPENIL+ G +KL DF
Sbjct: 154 --SKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKE 211
Query: 174 --------------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTY 213
E++ R+ + S D W GVL++E L G PF+ + +T
Sbjct: 212 AIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETM 271
Query: 214 ARILSLDIVYPSHIPDGAKDLI 235
IL + P + A+ L+
Sbjct: 272 TLILKAKLGMPQFLSTEAQSLL 293
Score = 81.0 bits (191), Expect = 4e-15
Identities = 68/215 (31%), Positives = 96/215 (44%), Gaps = 40/215 (18%)
Query: 34 SLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHSNILRL 92
++G G + K T A+K + KS+ R EIEI +H NI+ L
Sbjct: 423 TIGVGSYSECKRCVHKATNMEYAVKVIDKSK-------RDPSEEIEILLRYGQHPNIITL 475
Query: 93 LTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIH 152
+ D + +YLV E GGEL + Q F E +A+ ++ + VEY H V+H
Sbjct: 476 KDVYDDGKHVYLVTELMRGGELLDKILR--QKFFSEREASFVLHTIGKTVEYLHSQGVVH 533
Query: 153 RDIKPENIL-VAFSGD---LKLADF-------------------------EMIKREVYDV 183
RD+KP NIL V SG+ L++ DF E++KR+ YD
Sbjct: 534 RDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDE 593
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS 218
D W +G+LLY L G PF G T IL+
Sbjct: 594 GCDIWSLGILLYTMLAGYTPF-ANGPSDTPEEILT 627
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 108 bits (259), Expect = 2e-23
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 43 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 102
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 103 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 154
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 155 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 214
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T A IL
Sbjct: 215 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 274
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 275 KLGMPQFLSGEAQSLL 290
Score = 73.7 bits (173), Expect = 6e-13
Identities = 73/247 (29%), Positives = 105/247 (42%), Gaps = 48/247 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 415 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 467
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 468 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 525
Query: 148 HHVIHRDIKPENILVA-FSG---DLKLADFEMIK-------------------------R 178
V+HRD+KP NIL SG +++ DF K R
Sbjct: 526 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 585
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +G+LLY L G PF G D T IL +L I D
Sbjct: 586 QGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDSISDA 644
Query: 231 AKDLISK 237
AKD++SK
Sbjct: 645 AKDVVSK 651
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 108 bits (259), Expect = 2e-23
Identities = 79/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 116 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 175
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 176 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 227
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 228 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 287
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T A IL
Sbjct: 288 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKA 347
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 348 KLGMPQFLSGEAQSLL 363
Score = 73.7 bits (173), Expect = 6e-13
Identities = 73/247 (29%), Positives = 105/247 (42%), Gaps = 48/247 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 488 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHP 540
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 541 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 598
Query: 148 HHVIHRDIKPENILVA-FSG---DLKLADFEMIK-------------------------R 178
V+HRD+KP NIL SG +++ DF K R
Sbjct: 599 QGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKR 658
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +G+LLY L G PF G D T IL +L I D
Sbjct: 659 QGYDAACDIWSLGILLYTMLAGFTPF-ANGPDDTPEEILARIGSGKYALSGGNWDSISDA 717
Query: 231 AKDLISK 237
AKD++SK
Sbjct: 718 AKDVVSK 724
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 107 bits (258), Expect = 3e-23
Identities = 76/252 (30%), Positives = 125/252 (49%), Gaps = 33/252 (13%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI-VKS 68
I H K P FEL LGQG FG V + R+K G L A+K L K+ + V+
Sbjct: 57 ITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRD 116
Query: 69 KCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPE 128
+ ++ R+I ++ + H I++L F E ++YL+++F GG+++ L S + F E
Sbjct: 117 RVRTKMERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRL--SKEVLFTE 172
Query: 129 SKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------------- 173
Y+ ++A A+++ HQ +++RD+KPENIL+ G +KL DF
Sbjct: 173 EDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYS 232
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
E++ R + S D W GVL++E L G PF+ + ++T IL +
Sbjct: 233 FCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGM 292
Query: 224 PSHIPDGAKDLI 235
P + A+ L+
Sbjct: 293 PQFLSAEAQSLL 304
Score = 81.8 bits (193), Expect = 2e-15
Identities = 75/246 (30%), Positives = 108/246 (43%), Gaps = 48/246 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEI-QSHLKHS 87
+EL +G G + T A+K + KS+ R EIEI + +H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L F D R +YLV + GGEL + Q F E +A+ +Y ++ V+Y H
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILK--QKCFSEREASDILYVISKTVDYLHC 536
Query: 148 HHVIHRDIKPENILV----AFSGDLKLADF-------------------------EMIKR 178
V+HRD+KP NIL A + +++ DF E++ +
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQ 596
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +GVL Y L G PF G + T IL SL +I DG
Sbjct: 597 QGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGNWDNISDG 655
Query: 231 AKDLIS 236
AKDL+S
Sbjct: 656 AKDLLS 661
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 107 bits (258), Expect = 3e-23
Identities = 76/252 (30%), Positives = 125/252 (49%), Gaps = 33/252 (13%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI-VKS 68
I H K P FEL LGQG FG V + R+K G L A+K L K+ + V+
Sbjct: 57 ITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRD 116
Query: 69 KCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPE 128
+ ++ R+I ++ + H I++L F E ++YL+++F GG+++ L S + F E
Sbjct: 117 RVRTKMERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRL--SKEVLFTE 172
Query: 129 SKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------------- 173
Y+ ++A A+++ HQ +++RD+KPENIL+ G +KL DF
Sbjct: 173 EDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYS 232
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
E++ R + S D W GVL++E L G PF+ + ++T IL +
Sbjct: 233 FCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGM 292
Query: 224 PSHIPDGAKDLI 235
P + A+ L+
Sbjct: 293 PQFLSAEAQSLL 304
Score = 81.8 bits (193), Expect = 2e-15
Identities = 75/246 (30%), Positives = 108/246 (43%), Gaps = 48/246 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEI-QSHLKHS 87
+EL +G G + T A+K + KS+ R EIEI + +H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L F D R +YLV + GGEL + Q F E +A+ +Y ++ V+Y H
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILK--QKCFSEREASDILYVISKTVDYLHC 536
Query: 148 HHVIHRDIKPENILV----AFSGDLKLADF-------------------------EMIKR 178
V+HRD+KP NIL A + +++ DF E++ +
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQ 596
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +GVL Y L G PF G + T IL SL +I DG
Sbjct: 597 QGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGNWDNISDG 655
Query: 231 AKDLIS 236
AKDL+S
Sbjct: 656 AKDLLS 661
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 107 bits (258), Expect = 3e-23
Identities = 76/252 (30%), Positives = 125/252 (49%), Gaps = 33/252 (13%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI-VKS 68
I H K P FEL LGQG FG V + R+K G L A+K L K+ + V+
Sbjct: 57 ITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRD 116
Query: 69 KCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPE 128
+ ++ R+I ++ + H I++L F E ++YL+++F GG+++ L S + F E
Sbjct: 117 RVRTKMERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRL--SKEVLFTE 172
Query: 129 SKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------------- 173
Y+ ++A A+++ HQ +++RD+KPENIL+ G +KL DF
Sbjct: 173 EDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYS 232
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
E++ R + S D W GVL++E L G PF+ + ++T IL +
Sbjct: 233 FCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGM 292
Query: 224 PSHIPDGAKDLI 235
P + A+ L+
Sbjct: 293 PQFLSAEAQSLL 304
Score = 81.8 bits (193), Expect = 2e-15
Identities = 75/246 (30%), Positives = 108/246 (43%), Gaps = 48/246 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEI-QSHLKHS 87
+EL +G G + T A+K + KS+ R EIEI + +H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L F D R +YLV + GGEL + Q F E +A+ +Y ++ V+Y H
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILK--QKCFSEREASDILYVISKTVDYLHC 536
Query: 148 HHVIHRDIKPENILV----AFSGDLKLADF-------------------------EMIKR 178
V+HRD+KP NIL A + +++ DF E++ +
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQ 596
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +GVL Y L G PF G + T IL SL +I DG
Sbjct: 597 QGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGNWDNISDG 655
Query: 231 AKDLIS 236
AKDL+S
Sbjct: 656 AKDLLS 661
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 107 bits (258), Expect = 3e-23
Identities = 68/234 (29%), Positives = 113/234 (48%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN+++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinase
protein.
Length = 493
Score = 107 bits (256), Expect = 5e-23
Identities = 73/219 (33%), Positives = 112/219 (51%), Gaps = 30/219 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLT 94
+G+G +G V R K TG +VAIK +S K ++ MREI++ L+H N++ LL
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKM-VKKIAMREIKLLKQLRHENLVNLLE 68
Query: 95 WFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRD 154
++R YLV EF + L P G +Y++Q+ + + +CH H++IHRD
Sbjct: 69 VCKKKKRWYLVFEFV-DHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 155 IKPENILVAFSGDLKLADF-------------------------EMIKREV-YDVSVDHW 188
IKPENILV+ SG +KL DF E++ +V Y +VD W
Sbjct: 127 IKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVW 186
Query: 189 CIGVLLYEFLVGKPPFETEGE-DKTYARILSLDIVYPSH 226
IG L+ E +G+P F + + D+ Y ++ L + P H
Sbjct: 187 AIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRH 225
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 107 bits (256), Expect = 5e-23
Identities = 78/260 (30%), Positives = 128/260 (49%), Gaps = 33/260 (12%)
Query: 4 EVLELETKIINHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKS 63
E+++L+ K+ + SS + ++ E+ ++L G FG V + + K A+K + K
Sbjct: 433 EMIQLKEKVAR---FSSSSPF--QNLEIIATLAVGGFGRVELVKVKNENVAFAMKCIRKK 487
Query: 64 QIVKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQ 123
IV +K + V E I L I++L F D + +Y+++E GGEL+ L + +
Sbjct: 488 HIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRD--R 545
Query: 124 GRFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF---------- 173
G F E + + V +A +Y H+ +I+RD+KPEN+++ G LKL DF
Sbjct: 546 GSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQ 605
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILS- 218
E+I + +D SVD W +G+L+YE L G PPF + TY IL
Sbjct: 606 KTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKG 665
Query: 219 -LDIVYPSHIPDGAKDLISK 237
+ +P I +DLI +
Sbjct: 666 IEKMDFPRKITRRPEDLIRR 685
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 107 bits (256), Expect = 5e-23
Identities = 76/252 (30%), Positives = 125/252 (49%), Gaps = 33/252 (13%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI-VKS 68
I H K P FEL LGQG FG V + R+K G L A+K L K+ + V+
Sbjct: 57 ITHHVKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRG 116
Query: 69 KCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPE 128
+ ++ R+I ++ + H I++L F E ++YL+++F GG+++ L S + F E
Sbjct: 117 RVRTKMERDILVE--VNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRL--SKEVLFTE 172
Query: 129 SKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF--------------- 173
Y+ ++A A+++ HQ +++RD+KPENIL+ G +KL DF
Sbjct: 173 EDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYS 232
Query: 174 ----------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVY 223
E++ R + S D W GVL++E L G PF+ + ++T IL +
Sbjct: 233 FCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGM 292
Query: 224 PSHIPDGAKDLI 235
P + A+ L+
Sbjct: 293 PQLLSAEAQSLL 304
Score = 81.8 bits (193), Expect = 2e-15
Identities = 75/246 (30%), Positives = 108/246 (43%), Gaps = 48/246 (19%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEI-QSHLKHS 87
+EL +G G + T A+K + KS+ R EIEI + +H
Sbjct: 426 YELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK-------RDPSEEIEILMRYGQHP 478
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L F D R +YLV + GGEL + Q F E +A+ +Y ++ V+Y H
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILK--QKCFSEREASDILYVISKTVDYLHC 536
Query: 148 HHVIHRDIKPENILV----AFSGDLKLADF-------------------------EMIKR 178
V+HRD+KP NIL A + +++ DF E++ +
Sbjct: 537 QGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQ 596
Query: 179 EVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARIL--------SLDIVYPSHIPDG 230
+ YD + D W +GVL Y L G PF G + T IL SL +I DG
Sbjct: 597 QGYDAACDIWSLGVLFYTMLAGYTPF-ANGPNDTPEEILLRIGNGKFSLSGGNWDNISDG 655
Query: 231 AKDLIS 236
AKDL+S
Sbjct: 656 AKDLLS 661
>BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 107 bits (256), Expect = 5e-23
Identities = 73/219 (33%), Positives = 112/219 (51%), Gaps = 30/219 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLT 94
+G+G +G V R K TG +VAIK +S K ++ MREI++ L+H N++ LL
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKM-VKKIAMREIKLLKQLRHENLVNLLE 68
Query: 95 WFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRD 154
++R YLV EF + L P G +Y++Q+ + + +CH H++IHRD
Sbjct: 69 VCKKKKRWYLVFEFV-DHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 155 IKPENILVAFSGDLKLADF-------------------------EMIKREV-YDVSVDHW 188
IKPENILV+ SG +KL DF E++ +V Y +VD W
Sbjct: 127 IKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVW 186
Query: 189 CIGVLLYEFLVGKPPFETEGE-DKTYARILSLDIVYPSH 226
IG L+ E +G+P F + + D+ Y ++ L + P H
Sbjct: 187 AIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRH 225
>BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent
kinase-like 2 (CDC2-related kinase) protein.
Length = 493
Score = 107 bits (256), Expect = 5e-23
Identities = 73/219 (33%), Positives = 112/219 (51%), Gaps = 30/219 (13%)
Query: 35 LGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSNILRLLT 94
+G+G +G V R K TG +VAIK +S K ++ MREI++ L+H N++ LL
Sbjct: 10 VGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKM-VKKIAMREIKLLKQLRHENLVNLLE 68
Query: 95 WFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQHHVIHRD 154
++R YLV EF + L P G +Y++Q+ + + +CH H++IHRD
Sbjct: 69 VCKKKKRWYLVFEFV-DHTILDDLELFPNG-LDYQVVQKYLFQIINGIGFCHSHNIIHRD 126
Query: 155 IKPENILVAFSGDLKLADF-------------------------EMIKREV-YDVSVDHW 188
IKPENILV+ SG +KL DF E++ +V Y +VD W
Sbjct: 127 IKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVW 186
Query: 189 CIGVLLYEFLVGKPPFETEGE-DKTYARILSLDIVYPSH 226
IG L+ E +G+P F + + D+ Y ++ L + P H
Sbjct: 187 AIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRH 225
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 106 bits (255), Expect = 6e-23
Identities = 70/244 (28%), Positives = 122/244 (50%), Gaps = 31/244 (12%)
Query: 22 YKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMRE---I 78
++++ +DF + LG+G FG V +A K T + AIK L K IV +M E
Sbjct: 650 FQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIF 709
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
E + ++H ++ L F + + V+E+AAGG+L H+ F E +A Y V
Sbjct: 710 ETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAACV 766
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
++Y H+H +++RD+K +N+L+ G +K+ADF
Sbjct: 767 VLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAP 826
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E++ Y +VD W +GVL+YE LVG+ PF + E++ + I++ ++ YP + A
Sbjct: 827 EVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIS 886
Query: 234 LISK 237
++ +
Sbjct: 887 IMRR 890
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 106 bits (255), Expect = 6e-23
Identities = 70/244 (28%), Positives = 122/244 (50%), Gaps = 31/244 (12%)
Query: 22 YKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMRE---I 78
++++ +DF + LG+G FG V +A K T + AIK L K IV +M E
Sbjct: 650 FQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIF 709
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
E + ++H ++ L F + + V+E+AAGG+L H+ F E +A Y V
Sbjct: 710 ETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAACV 766
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
++Y H+H +++RD+K +N+L+ G +K+ADF
Sbjct: 767 VLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAP 826
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E++ Y +VD W +GVL+YE LVG+ PF + E++ + I++ ++ YP + A
Sbjct: 827 EVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIS 886
Query: 234 LISK 237
++ +
Sbjct: 887 IMRR 890
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 106 bits (255), Expect = 6e-23
Identities = 78/256 (30%), Positives = 124/256 (48%), Gaps = 41/256 (16%)
Query: 13 INHDAYGSSYKWSPRDFELGSSLGQGKFGHVHVAREKK---TGFLVAIKTLFKSQI---- 65
I+H K P FEL LGQG +G V + R+ K G L A+K L K+ +
Sbjct: 44 ISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRD 103
Query: 66 -VKSKCERQVMREIEIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQG 124
V+SK ER ++ E+ H I++L F E ++YL+++F GG+L+ L S +
Sbjct: 104 RVRSKMERDILAEVN------HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL--SKEV 155
Query: 125 RFPESKAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF----------- 173
F E Y+ ++A A+++ H +I+RD+KPENIL+ G +K+ DF
Sbjct: 156 MFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDK 215
Query: 174 --------------EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSL 219
E++ R + S D W GVL++E L G PF+ + +T + IL
Sbjct: 216 RAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKA 275
Query: 220 DIVYPSHIPDGAKDLI 235
+ P + A+ L+
Sbjct: 276 KLGMPQFLSGEAQSLL 291
Score = 64.1 bits (149), Expect = 4e-10
Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 10/134 (7%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHL-KHS 87
+E+ +G G + K T A+K + KS+ R EIEI +H
Sbjct: 416 YEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIGKSK-------RDPSEEIEILLRYGQHP 468
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+ L + D + +YLV+E GGEL + Q F E +A+ + + ++Y H
Sbjct: 469 NIITLKDVYDDGKFVYLVMELMRGGELLDRILR--QRYFSEREASDVLCTITKTMDYLHS 526
Query: 148 HHVIHRDIKPENIL 161
V+HRD+KP NIL
Sbjct: 527 QGVVHRDLKPSNIL 540
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 106 bits (255), Expect = 6e-23
Identities = 70/244 (28%), Positives = 122/244 (50%), Gaps = 31/244 (12%)
Query: 22 YKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMRE---I 78
++++ +DF + LG+G FG V +A K T + AIK L K IV +M E
Sbjct: 650 FQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIF 709
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
E + ++H ++ L F + + V+E+AAGG+L H+ F E +A Y V
Sbjct: 710 ETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAACV 766
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
++Y H+H +++RD+K +N+L+ G +K+ADF
Sbjct: 767 VLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAP 826
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E++ Y +VD W +GVL+YE LVG+ PF + E++ + I++ ++ YP + A
Sbjct: 827 EVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIS 886
Query: 234 LISK 237
++ +
Sbjct: 887 IMRR 890
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 106 bits (254), Expect = 9e-23
Identities = 70/244 (28%), Positives = 122/244 (50%), Gaps = 31/244 (12%)
Query: 22 YKWSPRDFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMRE---I 78
++++ +DF + LG+G FG V +A K T + AIK L K IV +M E
Sbjct: 602 FQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIF 661
Query: 79 EIQSHLKHSNILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQV 138
E + ++H ++ L F + + V+E+AAGG+L H+ F E +A Y V
Sbjct: 662 ETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDV---FSEPRAVFYAACV 718
Query: 139 ADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADF------------------------- 173
++Y H+H +++RD+K +N+L+ G +K+ADF
Sbjct: 719 VLGLQYLHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKEGMGYGDRTSTFCGTPEFLAP 778
Query: 174 EMIKREVYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKD 233
E++ Y +VD W +GVL+YE LVG+ PF + E++ + I++ ++ YP + A
Sbjct: 779 EVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAIS 838
Query: 234 LISK 237
++ +
Sbjct: 839 IMRR 842
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 106 bits (254), Expect = 9e-23
Identities = 68/234 (29%), Positives = 112/234 (47%), Gaps = 27/234 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
DF+ LG+G FG V + REK +G A+K L K I+ + E + + +H
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
+ L F + R+ V+E+ GGEL+ HL S + F E + Y ++ A++Y H
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHL--SRERVFSEDRTRFYGAEIVSALDYLHS 264
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIKREVYDV------------------------ 183
+++RD+K EN++ G +K+ DF + K + D
Sbjct: 265 GKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 184 -SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL DI +P + AK L+S
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLS 378
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 106 bits (254), Expect = 9e-23
Identities = 78/242 (32%), Positives = 123/242 (50%), Gaps = 35/242 (14%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L LG+G F V + TG A K + ++ + ++ +++ RE I LKH
Sbjct: 13 EYQLFEELGKGAFSVVRRCMKIPTGQEYAAK-IINTKKLSARDHQKLEREARICRLLKHP 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAFSGD---LKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E+++++
Sbjct: 130 MGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKD 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS----HIPDGAKDLI 235
Y VD W GV+LY LVG PPF E + + Y +I + +PS + AKDLI
Sbjct: 190 PYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 249
Query: 236 SK 237
+K
Sbjct: 250 NK 251
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 105 bits (253), Expect = 1e-22
Identities = 72/235 (30%), Positives = 118/235 (50%), Gaps = 29/235 (12%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+FE LG+G FG V + +EK T + A+K L K IV + E +Q + +H
Sbjct: 87 EFEYLKLLGKGTFGKVILVKEKATAYY-AMKILKKEVIVAKDEVAHTLTENRVQQNSRHP 145
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH- 146
+ RL F R+ V+E+A GGEL+ HL S + F E +A Y ++ A++Y H
Sbjct: 146 FLTRLKYSFQTHDRLCFVMEYANGGELFFHL--SRERVFAEDRARFYGAEIVSALDYLHS 203
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +V++RD+K EN+++ G +K+ DF + K + Y
Sbjct: 204 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 263
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL +I +P + AK L+S
Sbjct: 264 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 318
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 105 bits (253), Expect = 1e-22
Identities = 74/226 (32%), Positives = 116/226 (51%), Gaps = 31/226 (13%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+++L +G+G F V + TG A K + ++ + ++ +++ RE I LKHS
Sbjct: 13 EYQLYEDIGKGAFSVVRRCVKLCTGHEYAAK-IINTKKLSARDHQKLEREARICRLLKHS 71
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI+RL +E YLV + GGEL++ + + + E+ A+ I Q+ +AV +CHQ
Sbjct: 72 NIVRLHDSISEEGFHYLVFDLVTGGELFEDIV--AREYYSEADASHCIQQILEAVLHCHQ 129
Query: 148 HHVIHRDIKPENILVAF---SGDLKLADF-------------------------EMIKRE 179
V+HRD+KPEN+L+A +KLADF E++++E
Sbjct: 130 MGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 180 VYDVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPS 225
Y VD W GV+LY LVG PPF E + K Y +I + +PS
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPS 235
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 105 bits (252), Expect = 1e-22
Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 28/232 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ L +LG+G+ G V + TG VAIK + + ++ +S + V REI I ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+L+L + +++ +YLV+E +GGEL+ +L +GR +A ++ Q+ A+++CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVK--KGRLTPKEARKFFRQIVSALDFCHSY 150
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+ HRD+KPEN+L+ ++++ADF E+IK E YD
Sbjct: 151 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGR 210
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W GV+L+ LVG PF+ + + ++ P IP + L+
Sbjct: 211 RADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLL 262
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 105 bits (252), Expect = 1e-22
Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 28/232 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ L +LG+G+ G V + TG VAIK + + ++ +S + V REI I ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+L+L + +++ +YLV+E +GGEL+ +L +GR +A ++ Q+ A+++CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVK--KGRLTPKEARKFFRQIVSALDFCHSY 150
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+ HRD+KPEN+L+ ++++ADF E+IK E YD
Sbjct: 151 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGR 210
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W GV+L+ LVG PF+ + + ++ P IP + L+
Sbjct: 211 RADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLL 262
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 105 bits (252), Expect = 1e-22
Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 28/232 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ L +LG+G+ G V + TG VAIK + + ++ +S + V REI I ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+L+L + +++ +YLV+E +GGEL+ +L +GR +A ++ Q+ A+++CH +
Sbjct: 93 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVK--KGRLTPKEARKFFRQIVSALDFCHSY 150
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+ HRD+KPEN+L+ ++++ADF E+IK E YD
Sbjct: 151 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGR 210
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W GV+L+ LVG PF+ + + ++ P IP + L+
Sbjct: 211 RADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLL 262
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 105 bits (252), Expect = 1e-22
Identities = 68/232 (29%), Positives = 120/232 (51%), Gaps = 28/232 (12%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+ L +LG+G+ G V + TG VAIK + + ++ +S + V REI I ++H +
Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 108
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
+L+L + +++ +YLV+E +GGEL+ +L +GR +A ++ Q+ A+++CH +
Sbjct: 109 VLKLHDVYENKKYLYLVLEHVSGGELFDYLVK--KGRLTPKEARKFFRQIVSALDFCHSY 166
Query: 149 HVIHRDIKPENILVAFSGDLKLADF------------------------EMIKREVYD-V 183
+ HRD+KPEN+L+ ++++ADF E+IK E YD
Sbjct: 167 SICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGR 226
Query: 184 SVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLI 235
D W GV+L+ LVG PF+ + + ++ P IP + L+
Sbjct: 227 RADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLL 278
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 105 bits (251), Expect = 2e-22
Identities = 73/241 (30%), Positives = 120/241 (49%), Gaps = 36/241 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G +G G F V ++ TG A+K + K++ E + E+ I +KH N
Sbjct: 344 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPN 401
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ ++LV+E GG+L+ +T+S ++ E + +Y +A+A+ Y H
Sbjct: 402 IIMLVEEMETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANALRYLHGL 459
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 460 SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYG 519
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEG--EDKTYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF +E ++ + +IL+ + +P+ +I D AK+LIS
Sbjct: 520 LKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELIS 579
Query: 237 K 237
+
Sbjct: 580 Q 580
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 105 bits (251), Expect = 2e-22
Identities = 73/241 (30%), Positives = 120/241 (49%), Gaps = 36/241 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G +G G F V ++ TG A+K + K++ E + E+ I +KH N
Sbjct: 141 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPN 198
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ ++LV+E GG+L+ +T+S ++ E + +Y +A+A+ Y H
Sbjct: 199 IIMLVEEMETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANALRYLHGL 256
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 257 SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYG 316
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEG--EDKTYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF +E ++ + +IL+ + +P+ +I D AK+LIS
Sbjct: 317 LKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELIS 376
Query: 237 K 237
+
Sbjct: 377 Q 377
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 105 bits (251), Expect = 2e-22
Identities = 73/241 (30%), Positives = 120/241 (49%), Gaps = 36/241 (14%)
Query: 29 FELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHSN 88
+++G +G G F V ++ TG A+K + K++ E + E+ I +KH N
Sbjct: 424 YKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPN 481
Query: 89 ILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQH 148
I+ L+ ++LV+E GG+L+ +T+S ++ E + +Y +A+A+ Y H
Sbjct: 482 IIMLVEEMETATELFLVMELVKGGDLFDAITSST--KYTERDGSAMVYNLANALRYLHGL 539
Query: 149 HVIHRDIKPENILVAFSGD----LKLADF----------------------EMIKREVYD 182
++HRDIKPEN+LV D LKL DF E+I Y
Sbjct: 540 SIVHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYG 599
Query: 183 VSVDHWCIGVLLYEFLVGKPPFETEG--EDKTYARILSLDIVYPS----HIPDGAKDLIS 236
+ VD W GV+ Y L G PPF +E ++ + +IL+ + +P+ +I D AK+LIS
Sbjct: 600 LKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELIS 659
Query: 237 K 237
+
Sbjct: 660 Q 660
>AB012305-1|BAA32794.1| 264|Homo sapiens d-HSCDK2 protein.
Length = 264
Score = 105 bits (251), Expect = 2e-22
Identities = 53/150 (35%), Positives = 84/150 (56%), Gaps = 2/150 (1%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+F+ + +GQG +G V+ AR K TG +VA+K + + +REI + L H
Sbjct: 3 NFQKVAQIGQGTYGVVYKARNKSTGQMVALKKI-RLDTETEGVPSTAIREISLLKELNHP 61
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCHQ 147
NI++LL H E ++YLV EF +L K + S P Y++Q+ + +CH
Sbjct: 62 NIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 148 HHVIHRDIKPENILVAFSGDLKLADFEMIK 177
H V+HRD+KP+N+L+ G +KLADF + +
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLAR 150
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 104 bits (250), Expect = 3e-22
Identities = 71/235 (30%), Positives = 116/235 (49%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+FE LG+G FG V + +EK TG A+K L K IV + E + + +H
Sbjct: 149 EFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHP 208
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH- 146
+ L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A++Y H
Sbjct: 209 FLTALKYSFQTHDRLCFVMEYANGGELFFHL--SRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +V++RD+K EN+++ G +K+ DF + K + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL +I +P + AK L+S
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 104 bits (250), Expect = 3e-22
Identities = 71/235 (30%), Positives = 116/235 (49%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+FE LG+G FG V + +EK TG A+K L K IV + E + + +H
Sbjct: 149 EFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHP 208
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH- 146
+ L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A++Y H
Sbjct: 209 FLTALKYSFQTHDRLCFVMEYANGGELFFHL--SRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +V++RD+K EN+++ G +K+ DF + K + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL +I +P + AK L+S
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 104 bits (250), Expect = 3e-22
Identities = 71/235 (30%), Positives = 116/235 (49%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+FE LG+G FG V + +EK TG A+K L K IV + E + + +H
Sbjct: 149 EFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHP 208
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH- 146
+ L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A++Y H
Sbjct: 209 FLTALKYSFQTHDRLCFVMEYANGGELFFHL--SRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +V++RD+K EN+++ G +K+ DF + K + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL +I +P + AK L+S
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 104 bits (250), Expect = 3e-22
Identities = 71/235 (30%), Positives = 116/235 (49%), Gaps = 28/235 (11%)
Query: 28 DFELGSSLGQGKFGHVHVAREKKTGFLVAIKTLFKSQIVKSKCERQVMREIEIQSHLKHS 87
+FE LG+G FG V + +EK TG A+K L K IV + E + + +H
Sbjct: 149 EFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHP 208
Query: 88 NILRLLTWFHDERRIYLVVEFAAGGELYKHLTNSPQGRFPESKAARYIYQVADAVEYCH- 146
+ L F R+ V+E+A GGEL+ HL S + F E +A Y ++ A++Y H
Sbjct: 209 FLTALKYSFQTHDRLCFVMEYANGGELFFHL--SRERVFSEDRARFYGAEIVSALDYLHS 266
Query: 147 QHHVIHRDIKPENILVAFSGDLKLADFEMIKREV-------------------------Y 181
+ +V++RD+K EN+++ G +K+ DF + K + Y
Sbjct: 267 EKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326
Query: 182 DVSVDHWCIGVLLYEFLVGKPPFETEGEDKTYARILSLDIVYPSHIPDGAKDLIS 236
+VD W +GV++YE + G+ PF + +K + IL +I +P + AK L+S
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLS 381
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.138 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 37,157,401
Number of Sequences: 224733
Number of extensions: 1498564
Number of successful extensions: 10034
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2416
Number of HSP's successfully gapped in prelim test: 338
Number of HSP's that attempted gapping in prelim test: 2625
Number of HSP's gapped (non-prelim): 5030
length of query: 252
length of database: 73,234,838
effective HSP length: 88
effective length of query: 164
effective length of database: 53,458,334
effective search space: 8767166776
effective search space used: 8767166776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)
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