Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002349-TA|BGIBMGA002349-PA|IPR012307|Xylose
isomerase-like TIM barrel
(260 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomera... 199 7e-51
BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein. 167 3e-41
AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomera... 167 3e-41
AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein. 167 3e-41
AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apopto... 166 8e-41
BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein. 146 7e-35
AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein. 146 7e-35
AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomera... 142 1e-33
AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomera... 126 6e-29
AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomera... 122 1e-27
BC067235-1|AAH67235.1| 250|Homo sapiens Unknown (protein for MG... 30 9.4
AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein. 30 9.4
>AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 247
Score = 199 bits (486), Expect = 7e-51
Identities = 101/244 (41%), Positives = 153/244 (62%), Gaps = 7/244 (2%)
Query: 1 MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 60
++F ANLS++F E S + R A +GF+AVE +P+ + E + A + AGL+ + IN
Sbjct: 4 LRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 61 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 115
GD KGE+G+ +VPG++ F+ L + YAKAL +IH+MAG+V +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 116 HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 173
E F +NL +A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183
Query: 174 MLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYD 233
+DIFH Q + G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYK 243
Query: 234 EWVG 237
+VG
Sbjct: 244 GFVG 247
>BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein.
Length = 217
Score = 167 bits (407), Expect = 3e-41
Identities = 81/193 (41%), Positives = 125/193 (64%), Gaps = 7/193 (3%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVGLEYKAI 243
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG EY+
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLENEGYKGFVGCEYQPR 180
Query: 244 GNTKDGLTWINNY 256
G+T +GL+W+ +Y
Sbjct: 181 GDTVEGLSWLRSY 193
>AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 204
Score = 167 bits (406), Expect = 3e-41
Identities = 81/193 (41%), Positives = 125/193 (64%), Gaps = 7/193 (3%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVGLEYKAI 243
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG EY+
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPR 180
Query: 244 GNTKDGLTWINNY 256
G+T +GL+W+ +Y
Sbjct: 181 GDTVEGLSWLRSY 193
>AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein.
Length = 204
Score = 167 bits (406), Expect = 3e-41
Identities = 81/193 (41%), Positives = 125/193 (64%), Gaps = 7/193 (3%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVGLEYKAI 243
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG EY+
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPR 180
Query: 244 GNTKDGLTWINNY 256
G+T +GL+W+ +Y
Sbjct: 181 GDTVEGLSWLRSY 193
>AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apoptosis
protein E-CE1 protein.
Length = 229
Score = 166 bits (403), Expect = 8e-41
Identities = 89/224 (39%), Positives = 135/224 (60%), Gaps = 8/224 (3%)
Query: 1 MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 60
++F ANLS++F E + R A +GF+AVE +P+ + E + A + AGL+ + IN
Sbjct: 4 LRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 61 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 115
GD KGE+G+ +VPG++ F+ L + YAKAL +IH+MAG+V +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 116 HWE-TFEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 173
E F +NL +A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183
Query: 174 MLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPN-RNEPDTPG 216
+DIFH Q + G++T NI + LP +GHVQ+AQ P R PG
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQGPRPRGAQQAPG 227
>BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein.
Length = 174
Score = 146 bits (354), Expect = 7e-35
Identities = 73/174 (41%), Positives = 111/174 (63%), Gaps = 7/174 (4%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVG 237
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVG 174
>AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein.
Length = 174
Score = 146 bits (354), Expect = 7e-35
Identities = 73/174 (41%), Positives = 111/174 (63%), Gaps = 7/174 (4%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVG 237
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVG 174
>AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 229
Score = 142 bits (344), Expect = 1e-33
Identities = 70/162 (43%), Positives = 106/162 (65%), Gaps = 7/162 (4%)
Query: 102 IHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLS 154
IH+MAG+V + E F +NL +A VL E++ GL+EPIN + + P+YFL
Sbjct: 57 IHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLD 116
Query: 155 DYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEPDT 214
+A I++++ PNL+L +DIFH Q + G++T NI + LP +GHVQ+AQVP R EP +
Sbjct: 117 TPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPSS 176
Query: 215 PGEINYKYVLEHLAKSGYDEWVGLEYKAIGNTKDGLTWINNY 256
PGE+N+ Y+ + L GY +VG EY+ G+T +GL+W+ +Y
Sbjct: 177 PGELNFPYLFQLLEDEGYKGFVGCEYQPRGDTVEGLSWLRSY 218
>AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 165
Score = 126 bits (305), Expect = 6e-29
Identities = 68/174 (39%), Positives = 106/174 (60%), Gaps = 16/174 (9%)
Query: 71 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 124
+G+ +VPG++ F+ L + +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAV---------RIHLMAGRVPQGADRIAVKAEMEAVFLENL 51
Query: 125 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 183
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 52 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 111
Query: 184 AGDITHNITKLLPYIGHVQIAQVPNRNEPDTPGEINYKYVLEHLAKSGYDEWVG 237
G++T NI + LP +GHVQ+AQVP R EP +PGE+N+ Y+ + L GY +VG
Sbjct: 112 DGNLTGNIREFLPIVGHVQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVG 165
>AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 180
Score = 122 bits (294), Expect = 1e-27
Identities = 62/144 (43%), Positives = 93/144 (64%), Gaps = 7/144 (4%)
Query: 101 KIHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFL 153
+IH+MAG+V + E F +NL +A VL E++ GL+EPIN + + P+YFL
Sbjct: 37 RIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFL 96
Query: 154 SDYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEPD 213
+A I++++ PNL+L +DIFH Q + G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 97 DTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEPS 156
Query: 214 TPGEINYKYVLEHLAKSGYDEWVG 237
+PGE+N+ Y+ + L GY +VG
Sbjct: 157 SPGELNFPYLFQLLEDEGYKGFVG 180
>BC067235-1|AAH67235.1| 250|Homo sapiens Unknown (protein for
MGC:72175) protein.
Length = 250
Score = 29.9 bits (64), Expect = 9.4
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 65 DTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKA 96
D T G + +TSVP E T L T EY+ A
Sbjct: 147 DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPA 178
>AB033063-1|BAA86551.2| 1268|Homo sapiens KIAA1237 protein protein.
Length = 1268
Score = 29.9 bits (64), Expect = 9.4
Identities = 14/32 (43%), Positives = 17/32 (53%)
Query: 65 DTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKA 96
D T G + +TSVP E T L T EY+ A
Sbjct: 796 DATTGLIPLTSVPTSAKEMTTKLGVTAEYSPA 827
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.136 0.397
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 37,988,306
Number of Sequences: 224733
Number of extensions: 1526405
Number of successful extensions: 2615
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2586
Number of HSP's gapped (non-prelim): 12
length of query: 260
length of database: 73,234,838
effective HSP length: 88
effective length of query: 172
effective length of database: 53,458,334
effective search space: 9194833448
effective search space used: 9194833448
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 64 (29.9 bits)
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