Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002340-TA|BGIBMGA002340-PA|IPR000357|HEAT
(590 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2 (... 890 0.0
J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory... 887 0.0
CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein. 887 0.0
M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tu... 886 0.0
BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2 (... 855 0.0
AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2 s... 854 0.0
AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A ... 853 0.0
AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A ... 853 0.0
M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A re... 825 0.0
AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens ... 646 0.0
BC060829-1|AAH60829.1| 933|Homo sapiens protein phosphatase 4, ... 75 7e-13
AF200478-1|AAL78298.1| 950|Homo sapiens protein serine/threonin... 75 7e-13
AF111106-1|AAD09818.1| 933|Homo sapiens protein serine/threonin... 75 7e-13
BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein. 48 1e-04
AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein. 48 1e-04
U79267-1|AAB50211.1| 173|Homo sapiens unknown protein. 47 2e-04
AF054284-1|AAC97189.1| 1304|Homo sapiens spliceosomal protein SA... 46 4e-04
AL354776-4|CAM14101.1| 235|Homo sapiens protein phosphatase 4, ... 45 9e-04
Y08991-1|CAA70176.1| 1358|Homo sapiens adaptor protein protein. 38 0.13
BC127106-1|AAI27107.1| 1358|Homo sapiens phosphoinositide-3-kina... 38 0.13
BC127105-1|AAI27106.1| 1358|Homo sapiens phosphoinositide-3-kina... 38 0.13
BC110318-1|AAI10319.1| 1358|Homo sapiens phosphoinositide-3-kina... 38 0.13
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 37 0.17
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 37 0.17
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 37 0.17
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 37 0.17
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 37 0.17
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 37 0.23
U88836-1|AAD00655.1| 994|Homo sapiens translational activator G... 36 0.40
U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein. 36 0.40
D86973-1|BAA13209.2| 2675|Homo sapiens KIAA0219 protein. 36 0.40
BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing ... 36 0.40
AC004812-3|AAC83183.1| 2392|Homo sapiens WUGSC:H_267D11.3 protein. 36 0.40
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 35 0.93
BC100980-1|AAI00981.1| 415|Homo sapiens PPP4R1L protein protein. 34 1.2
BC100979-1|AAI00980.1| 415|Homo sapiens PPP4R1L protein protein. 34 1.2
AL354834-1|CAI94892.2| 386|Homo sapiens protein phosphatase 4, ... 34 1.2
AL354776-1|CAI94993.2| 386|Homo sapiens protein phosphatase 4, ... 34 1.2
BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein. 33 2.8
BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein. 33 2.8
AL355355-6|CAI16549.1| 577|Homo sapiens optineurin protein. 33 2.8
AL355355-5|CAI16550.1| 571|Homo sapiens optineurin protein. 33 2.8
AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3 pr... 33 2.8
AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2 pr... 33 2.8
AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1 pr... 33 2.8
AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein. 32 4.9
AF061034-2|AAC16047.1| 520|Homo sapiens FIP2 protein. 32 4.9
AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein. 32 4.9
BC031688-1|AAH31688.1| 490|Homo sapiens TEKT3 protein protein. 31 8.6
BC014662-1|AAH14662.1| 688|Homo sapiens SCY1-like 3 (S. cerevis... 31 8.6
AY144493-1|AAN41656.1| 742|Homo sapiens ezrin-binding protein P... 31 8.6
AL117233-1|CAB55300.1| 688|Homo sapiens hypothetical protein pr... 31 8.6
AL031297-3|CAI23518.1| 742|Homo sapiens ezrin-binding partner P... 31 8.6
AL031297-2|CAB52564.2| 688|Homo sapiens ezrin-binding partner P... 31 8.6
AL031297-1|CAI23517.1| 588|Homo sapiens ezrin-binding partner P... 31 8.6
AF540957-1|AAN23123.1| 688|Homo sapiens ezrin-binding partner P... 31 8.6
AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein. 31 8.6
AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein. 31 8.6
>BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A , alpha isoform
protein.
Length = 589
Score = 890 bits (2201), Expect = 0.0
Identities = 438/585 (74%), Positives = 495/585 (84%), Gaps = 2/585 (0%)
Query: 1 MAASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTET 60
MAA+D D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+T
Sbjct: 1 MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDT 58
Query: 61 IYDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEH 120
IYDEDEVLLALAEQLG+F LVGG E+ HCLLPPLE+LA VEETVVRDKAV SLRA++
Sbjct: 59 IYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118
Query: 121 HSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDT 180
HSP LE HFVPLV+RLAGGDWFTSRTSACGLFSVCYPRVS+ VKAELRQ+FR+LC DDT
Sbjct: 119 HSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDT 178
Query: 181 PMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPE 240
PMVRRAAA KLGEFAKV+E++ VKS++IP+F LA D+QDSVR E
Sbjct: 179 PMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQE 238
Query: 241 DMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEV 300
D+E VMPT+R + D SWRVRYMVADKF ELQ+AVG E+ +TDL FQ L+KD EAEV
Sbjct: 239 DLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEV 298
Query: 301 RAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGR 360
RAAA+ KVK+FC NL +E++IM+ ILP IK+LV DANQHVKSALASVIMGLSPI+G+
Sbjct: 299 RAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGK 358
Query: 361 QNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWR 420
NTIEHLLPLFL QLKDECPEVRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWR
Sbjct: 359 DNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWR 418
Query: 421 VRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWA 480
VRLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NLKKLVE++G +WA
Sbjct: 419 VRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWA 478
Query: 481 ENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRF 540
+IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL MA D VANVRF
Sbjct: 479 HATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRF 538
Query: 541 NVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAI 585
NVAK+LQ + LD + +Q +VKP+LEKL D DVDVKYFA EA+
Sbjct: 539 NVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583
Score = 93.1 bits (221), Expect = 2e-18
Identities = 90/411 (21%), Positives = 161/411 (39%), Gaps = 10/411 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE+IP + DE D V L E + L+ +
Sbjct: 181 VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL 240
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ + VP Q L R
Sbjct: 241 EALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA 300
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A +SA + +++ + L D V+ A A + + ++ +
Sbjct: 301 AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN 360
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA +K ++K +E
Sbjct: 421 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL---VEKFGKEW 477
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
T I+P++ + D N + I LS + G+ T +H+LP L D V
Sbjct: 478 AHAT-IIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV 536
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
R N+ +L+ + ++ L + P + +L +D V+ E + +L+
Sbjct: 537 RFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS 587
Score = 89.8 bits (213), Expect = 2e-17
Identities = 90/422 (21%), Positives = 166/422 (39%), Gaps = 18/422 (4%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P D+ + +
Sbjct: 21 RNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLV 80
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDS 296
PE + ++P + +L+ VR DK VE +A+ E + +DL F L+K
Sbjct: 81 GGPEYVHC-LLPPLESLATVEETVVR----DKAVESLRAISHEHSPSDLEAHFVPLVKRL 135
Query: 297 EA----EVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIM 352
R +A G + A + + ++L D V+ A AS +
Sbjct: 136 AGGDWFTSRTSACGLFSVCYPRVSSA-----VKAELRQYFRNLCSDDTPMVRRAAASKLG 190
Query: 353 GLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVE 412
+ ++ N ++P+F DE VRL + + +++ + L ++P + +
Sbjct: 191 EFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQ 250
Query: 413 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLV 472
AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 251 AAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFC 310
Query: 473 EQYGPQWAEN----NVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVL 528
E EN ++P + + + N + I LS + GKD T LLP L
Sbjct: 311 ENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL 370
Query: 529 SMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ D VR N+ L + + + + + P + +L D V+ E + +
Sbjct: 371 AQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLL 430
Query: 589 AG 590
AG
Sbjct: 431 AG 432
Score = 76.6 bits (180), Expect = 2e-13
Identities = 76/390 (19%), Positives = 155/390 (39%), Gaps = 8/390 (2%)
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
VK++L F L DD VR ++++ ++P L+ D VR
Sbjct: 162 VKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVR 221
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + V + Q + QE + + +D VR A K + L KA
Sbjct: 222 LLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTE----LQKAVGPE 277
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVG---RQNTI-EHLLPLFLTQLKDE 378
I T ++P ++L+ D V++A + + + R+N I +LP + D
Sbjct: 278 ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDA 337
Query: 379 CPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQ 438
V+ + S + ++ ++G ++ LLP + +D VRL II ++ + +G
Sbjct: 338 NQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGI 397
Query: 439 EFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYL 498
+ L + D + +R A + L Q G ++ + + + + Y
Sbjct: 398 RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYA 457
Query: 499 HRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVI 558
R + L E GK+ ++P VL+M+ D R + ++++ +
Sbjct: 458 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 517
Query: 559 QPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ P + ++ DP +V++ ++++ I
Sbjct: 518 TKHMLPTVLRMAGDPVANVRFNVAKSLQKI 547
>J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory
subunit protein.
Length = 589
Score = 887 bits (2195), Expect = 0.0
Identities = 437/585 (74%), Positives = 494/585 (84%), Gaps = 2/585 (0%)
Query: 1 MAASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTET 60
MAA+D D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+T
Sbjct: 1 MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDT 58
Query: 61 IYDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEH 120
IYDEDEVLLALAEQLG+F LVGG E+ HCLLPPLE+LA VEETVVRDKAV SLRA++
Sbjct: 59 IYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118
Query: 121 HSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDT 180
HSP LE HFVPLV+RLAGGDWFTSRTSACGLFSVCYPRVS+ VKAELRQ+FR+LC DDT
Sbjct: 119 HSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDT 178
Query: 181 PMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPE 240
PMVRRAAA KLGEFAKV+E++ VKS++IP+F LA D+QDSVR E
Sbjct: 179 PMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQE 238
Query: 241 DMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEV 300
D+E VMPT+R + D SW VRYMVADKF ELQ+AVG E+ +TDL FQ L+KD EAEV
Sbjct: 239 DLEALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEV 298
Query: 301 RAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGR 360
RAAA+ KVK+FC NL +E++IM+ ILP IK+LV DANQHVKSALASVIMGLSPI+G+
Sbjct: 299 RAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGK 358
Query: 361 QNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWR 420
NTIEHLLPLFL QLKDECPEVRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWR
Sbjct: 359 DNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWR 418
Query: 421 VRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWA 480
VRLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NLKKLVE++G +WA
Sbjct: 419 VRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWA 478
Query: 481 ENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRF 540
+IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL MA D VANVRF
Sbjct: 479 HATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRF 538
Query: 541 NVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAI 585
NVAK+LQ + LD + +Q +VKP+LEKL D DVDVKYFA EA+
Sbjct: 539 NVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583
Score = 94.3 bits (224), Expect = 1e-18
Identities = 90/411 (21%), Positives = 161/411 (39%), Gaps = 10/411 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE+IP + DE D V L E + L+ +
Sbjct: 181 VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL 240
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ + VP Q L R
Sbjct: 241 EALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA 300
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A +SA + +++ + L D V+ A A + + ++ +
Sbjct: 301 AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN 360
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA +K ++K +E
Sbjct: 421 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL---VEKFGKEW 477
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
T I+P++ + D N + I LS + G+ T +H+LP L D V
Sbjct: 478 AHAT-IIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV 536
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
R N+ +L+ + ++ L + P + +L +D V+ E + +L+
Sbjct: 537 RFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS 587
Score = 87.4 bits (207), Expect = 1e-16
Identities = 89/422 (21%), Positives = 165/422 (39%), Gaps = 18/422 (4%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P D+ + +
Sbjct: 21 RNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLV 80
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDS 296
PE + ++P + +L+ VR DK VE +A+ E + +DL F L+K
Sbjct: 81 GGPEYVHC-LLPPLESLATVEETVVR----DKAVESLRAISHEHSPSDLEAHFVPLVKRL 135
Query: 297 EA----EVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIM 352
R +A G + A + + ++L D V+ A AS +
Sbjct: 136 AGGDWFTSRTSACGLFSVCYPRVSSA-----VKAELRQYFRNLCSDDTPMVRRAAASKLG 190
Query: 353 GLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVE 412
+ ++ N ++P+F DE VRL + + +++ + L ++P + +
Sbjct: 191 EFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQ 250
Query: 413 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLV 472
AED W VR + + L +G E L + + D +R AA+ +K+
Sbjct: 251 AAEDKSWAVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFC 310
Query: 473 EQYGPQWAEN----NVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVL 528
E EN ++P + + + N + I LS + GKD T LLP L
Sbjct: 311 ENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL 370
Query: 529 SMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ D VR N+ L + + + + + P + +L D V+ E + +
Sbjct: 371 AQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLL 430
Query: 589 AG 590
AG
Sbjct: 431 AG 432
Score = 78.6 bits (185), Expect = 6e-14
Identities = 77/390 (19%), Positives = 156/390 (40%), Gaps = 8/390 (2%)
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
VK++L F L DD VR ++++ ++P L+ D VR
Sbjct: 162 VKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVR 221
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + V + Q + QE DL + L+ + + A V D L KA
Sbjct: 222 LLAVEACVNIAQLLPQE----DLEALVMPTLRQAAEDKSWAVRYMVADKFTELQKAVGPE 277
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVG---RQNTI-EHLLPLFLTQLKDE 378
I T ++P ++L+ D V++A + + + R+N I +LP + D
Sbjct: 278 ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDA 337
Query: 379 CPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQ 438
V+ + S + ++ ++G ++ LLP + +D VRL II ++ + +G
Sbjct: 338 NQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGI 397
Query: 439 EFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYL 498
+ L + D + +R A + L Q G ++ + + + + Y
Sbjct: 398 RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYA 457
Query: 499 HRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVI 558
R + L E GK+ ++P VL+M+ D R + ++++ +
Sbjct: 458 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 517
Query: 559 QPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ P + ++ DP +V++ ++++ I
Sbjct: 518 TKHMLPTVLRMAGDPVANVRFNVAKSLQKI 547
>CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein.
Length = 589
Score = 887 bits (2194), Expect = 0.0
Identities = 437/585 (74%), Positives = 494/585 (84%), Gaps = 2/585 (0%)
Query: 1 MAASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTET 60
MAA+D D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+T
Sbjct: 1 MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDT 58
Query: 61 IYDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEH 120
IYDEDEVLLALAEQLG+F LVGG E+ HCLLPPLE+LA VEETVVRDKAV SLRA++
Sbjct: 59 IYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118
Query: 121 HSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDT 180
HSP LE HFVPLV+RLAGGDWFTSRTSACGLFSVCYPRVS+ VKAELRQ+FR+LC DDT
Sbjct: 119 HSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDT 178
Query: 181 PMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPE 240
PMVRRAAA KLGEFAKV+E++ VKS++IP+F LA D+QDSVR E
Sbjct: 179 PMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQE 238
Query: 241 DMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEV 300
D+E VMPT+R + D SWRVRYMVADKF ELQ+AVG E+ +TDL FQ L+KD EAEV
Sbjct: 239 DLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEV 298
Query: 301 RAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGR 360
RAAA+ KVK+FC NL +E++IM+ ILP IK+LV DANQHVKSALASVIMGLSPI+G+
Sbjct: 299 RAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGK 358
Query: 361 QNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWR 420
NTIEHLLPLFL QLKDECPEVRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWR
Sbjct: 359 DNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWR 418
Query: 421 VRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWA 480
VRLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NLKKLVE++G +WA
Sbjct: 419 VRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWA 478
Query: 481 ENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRF 540
+IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL MA D VANVRF
Sbjct: 479 HATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRF 538
Query: 541 NVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAI 585
NVAK+LQ + D + +Q +VKP+LEKL D DVDVKYFA EA+
Sbjct: 539 NVAKSLQKIGPIPDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583
Score = 91.1 bits (216), Expect = 1e-17
Identities = 90/411 (21%), Positives = 160/411 (38%), Gaps = 10/411 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE+IP + DE D V L E + L+ +
Sbjct: 181 VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL 240
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ + VP Q L R
Sbjct: 241 EALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA 300
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A +SA + +++ + L D V+ A A + + ++ +
Sbjct: 301 AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN 360
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA +K ++K +E
Sbjct: 421 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL---VEKFGKEW 477
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
T I+P++ + D N + I LS + G+ T +H+LP L D V
Sbjct: 478 AHAT-IIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV 536
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
R N+ +L+ + + L + P + +L +D V+ E + +L+
Sbjct: 537 RFNVAKSLQKIGPIPDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS 587
Score = 89.8 bits (213), Expect = 2e-17
Identities = 90/422 (21%), Positives = 166/422 (39%), Gaps = 18/422 (4%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P D+ + +
Sbjct: 21 RNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLV 80
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDS 296
PE + ++P + +L+ VR DK VE +A+ E + +DL F L+K
Sbjct: 81 GGPEYVHC-LLPPLESLATVEETVVR----DKAVESLRAISHEHSPSDLEAHFVPLVKRL 135
Query: 297 EA----EVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIM 352
R +A G + A + + ++L D V+ A AS +
Sbjct: 136 AGGDWFTSRTSACGLFSVCYPRVSSA-----VKAELRQYFRNLCSDDTPMVRRAAASKLG 190
Query: 353 GLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVE 412
+ ++ N ++P+F DE VRL + + +++ + L ++P + +
Sbjct: 191 EFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQ 250
Query: 413 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLV 472
AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 251 AAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFC 310
Query: 473 EQYGPQWAEN----NVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVL 528
E EN ++P + + + N + I LS + GKD T LLP L
Sbjct: 311 ENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL 370
Query: 529 SMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ D VR N+ L + + + + + P + +L D V+ E + +
Sbjct: 371 AQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLL 430
Query: 589 AG 590
AG
Sbjct: 431 AG 432
Score = 76.6 bits (180), Expect = 2e-13
Identities = 76/390 (19%), Positives = 155/390 (39%), Gaps = 8/390 (2%)
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
VK++L F L DD VR ++++ ++P L+ D VR
Sbjct: 162 VKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVR 221
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + V + Q + QE + + +D VR A K + L KA
Sbjct: 222 LLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTE----LQKAVGPE 277
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVG---RQNTI-EHLLPLFLTQLKDE 378
I T ++P ++L+ D V++A + + + R+N I +LP + D
Sbjct: 278 ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDA 337
Query: 379 CPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQ 438
V+ + S + ++ ++G ++ LLP + +D VRL II ++ + +G
Sbjct: 338 NQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGI 397
Query: 439 EFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYL 498
+ L + D + +R A + L Q G ++ + + + + Y
Sbjct: 398 RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYA 457
Query: 499 HRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVI 558
R + L E GK+ ++P VL+M+ D R + ++++ +
Sbjct: 458 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 517
Query: 559 QPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ P + ++ DP +V++ ++++ I
Sbjct: 518 TKHMLPTVLRMAGDPVANVRFNVAKSLQKI 547
>M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tumor
antigen-associated 61-kD protein mRNA, 5' end. ).
Length = 589
Score = 886 bits (2193), Expect = 0.0
Identities = 437/585 (74%), Positives = 494/585 (84%), Gaps = 2/585 (0%)
Query: 1 MAASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTET 60
MAA+D D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+T
Sbjct: 1 MAAADG--DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDT 58
Query: 61 IYDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEH 120
IYDEDEVLLALAEQLG+F LVGG E+ HCLLPPLE+LA VEETVVRDKAV SLRA++
Sbjct: 59 IYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118
Query: 121 HSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDT 180
HSP LE HFV LV+RLAGGDWFTSRTSACGLFSVCYPRVS+ VKAELRQ+FR+LC DDT
Sbjct: 119 HSPSDLEAHFVALVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDT 178
Query: 181 PMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPE 240
PMVRRAAA KLGEFAKV+E++ VKS++IP+F LA D+QDSVR E
Sbjct: 179 PMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQE 238
Query: 241 DMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEV 300
D+E VMPT+R + D SWRVRYMVADKF ELQ+AVG E+ +TDL FQ L+KD EAEV
Sbjct: 239 DLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEV 298
Query: 301 RAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGR 360
RAAA+ KVK+FC NL +E++IM+ ILP IK+LV DANQHVKSALASVIMGLSPI+G+
Sbjct: 299 RAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGK 358
Query: 361 QNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWR 420
NTIEHLLPLFL QLKDECPEVRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWR
Sbjct: 359 DNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWR 418
Query: 421 VRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWA 480
VRLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NLKKLVE++G +WA
Sbjct: 419 VRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWA 478
Query: 481 ENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRF 540
+IPKVL MS + NYLHRMT LFCINVLSEVCG+DITT+ +LPTVL MA D VANVRF
Sbjct: 479 HATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRF 538
Query: 541 NVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAI 585
NVAK+LQ + LD + +Q +VKP+LEKL D DVDVKYFA EA+
Sbjct: 539 NVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL 583
Score = 93.1 bits (221), Expect = 2e-18
Identities = 90/411 (21%), Positives = 161/411 (39%), Gaps = 10/411 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE+IP + DE D V L E + L+ +
Sbjct: 181 VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL 240
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ + VP Q L R
Sbjct: 241 EALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA 300
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A +SA + +++ + L D V+ A A + + ++ +
Sbjct: 301 AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN 360
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 361 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 420
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA +K ++K +E
Sbjct: 421 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL---VEKFGKEW 477
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
T I+P++ + D N + I LS + G+ T +H+LP L D V
Sbjct: 478 AHAT-IIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV 536
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
R N+ +L+ + ++ L + P + +L +D V+ E + +L+
Sbjct: 537 RFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS 587
Score = 91.9 bits (218), Expect = 6e-18
Identities = 91/422 (21%), Positives = 167/422 (39%), Gaps = 18/422 (4%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P D+ + +
Sbjct: 21 RNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLV 80
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDS 296
PE + ++P + +L+ VR DK VE +A+ E + +DL F AL+K
Sbjct: 81 GGPEYVHC-LLPPLESLATVEETVVR----DKAVESLRAISHEHSPSDLEAHFVALVKRL 135
Query: 297 EA----EVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIM 352
R +A G + A + + ++L D V+ A AS +
Sbjct: 136 AGGDWFTSRTSACGLFSVCYPRVSSA-----VKAELRQYFRNLCSDDTPMVRRAAASKLG 190
Query: 353 GLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVE 412
+ ++ N ++P+F DE VRL + + +++ + L ++P + +
Sbjct: 191 EFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQ 250
Query: 413 LAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLV 472
AED WRVR + + L +G E L + + D +R AA+ +K+
Sbjct: 251 AAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFC 310
Query: 473 EQYGPQWAEN----NVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVL 528
E EN ++P + + + N + I LS + GKD T LLP L
Sbjct: 311 ENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFL 370
Query: 529 SMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ D VR N+ L + + + + + P + +L D V+ E + +
Sbjct: 371 AQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLL 430
Query: 589 AG 590
AG
Sbjct: 431 AG 432
Score = 76.6 bits (180), Expect = 2e-13
Identities = 76/390 (19%), Positives = 155/390 (39%), Gaps = 8/390 (2%)
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
VK++L F L DD VR ++++ ++P L+ D VR
Sbjct: 162 VKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVR 221
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + V + Q + QE + + +D VR A K + L KA
Sbjct: 222 LLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTE----LQKAVGPE 277
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVG---RQNTI-EHLLPLFLTQLKDE 378
I T ++P ++L+ D V++A + + + R+N I +LP + D
Sbjct: 278 ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDA 337
Query: 379 CPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQ 438
V+ + S + ++ ++G ++ LLP + +D VRL II ++ + +G
Sbjct: 338 NQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGI 397
Query: 439 EFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYL 498
+ L + D + +R A + L Q G ++ + + + + Y
Sbjct: 398 RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYA 457
Query: 499 HRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVI 558
R + L E GK+ ++P VL+M+ D R + ++++ +
Sbjct: 458 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 517
Query: 559 QPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ P + ++ DP +V++ ++++ I
Sbjct: 518 TKHMLPTVLRMAGDPVANVRFNVAKSLQKI 547
>BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A, beta isoform
protein.
Length = 667
Score = 855 bits (2114), Expect = 0.0
Identities = 420/588 (71%), Positives = 485/588 (82%), Gaps = 1/588 (0%)
Query: 2 AASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETI 61
AA G D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+TI
Sbjct: 13 AAGGDG-DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTI 71
Query: 62 YDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHH 121
YDEDEVLLALAEQLG+F LVGG +FAHCLLPPLE LA VEETVVRDKAV SLR +++ H
Sbjct: 72 YDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH 131
Query: 122 SPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTP 181
+P ALE +FVPLV+RLA GDWFTSRTSACGLFSVCYPR S VKAE+RQ FRSLC DDTP
Sbjct: 132 TPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTP 191
Query: 182 MVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPED 241
MVRRAAA KLGEFAKV+E++ VKS+++P+F LA D+QDSVR + +D
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 242 MEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVR 301
+E VMPT+R + D SWRVRYMVAD+F ELQ+A+G ++ DL FQ LLKD EAEVR
Sbjct: 252 LETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVR 311
Query: 302 AAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQ 361
AAAA KVK+ NL +E IIM ILP IK+LV D NQHVKSALASVIMGLS I+G++
Sbjct: 312 AAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKE 371
Query: 362 NTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRV 421
NTIEHLLPLFL QLKDECP+VRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWRV
Sbjct: 372 NTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRV 431
Query: 422 RLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAE 481
RLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NL KLV+++G +WA+
Sbjct: 432 RLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQ 491
Query: 482 NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFN 541
N ++PKVL M+++ NYLHRMT LFCIN LSE CG++ITT+ +LP VL MA D VANVRFN
Sbjct: 492 NTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFN 551
Query: 542 VAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
VAK+LQ + LD +Q +VKPVL+KL D D+DVKYFA EAI+ +A
Sbjct: 552 VAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVVA 599
Score = 92.7 bits (220), Expect = 3e-18
Identities = 89/422 (21%), Positives = 160/422 (37%), Gaps = 10/422 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE++P T DE D V L E S L+ +
Sbjct: 193 VRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDL 252
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ +P Q L R
Sbjct: 253 ETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRA 312
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A + + ++ + + L D V+ A A + + ++ E
Sbjct: 313 AAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKEN 372
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 373 TIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 432
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA + M L +
Sbjct: 433 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNL----MKLVQKFGTE 488
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
I+P++ + D N + I LS G++ T + +LP+ L D+ V
Sbjct: 489 WAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANV 548
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFD 442
R N+ +L+ + ++ L + P + +L +D V+ E + ++A +L + F
Sbjct: 549 RFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVVAQRLRKLEFP 608
Query: 443 EK 444
K
Sbjct: 609 VK 610
Score = 87.8 bits (208), Expect = 9e-17
Identities = 91/419 (21%), Positives = 166/419 (39%), Gaps = 12/419 (2%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P F+ D+D V
Sbjct: 33 RNEDVQLRLNSIKKLSTIALALGVERTRSELLP-FLTDTIYDEDEVLLALAEQLGNFTGL 91
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKD- 295
D ++P + L+ VR DK VE + + QE L F L+K
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVR----DKAVESLRQISQEHTPVALEAYFVPLVKRL 147
Query: 296 SEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLS 355
+ + + F + +A + + I Q + L D V+ A AS + +
Sbjct: 148 ASGDWFTSRTSACGLFSVCYPRA--SNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFA 205
Query: 356 PIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
++ + ++PLF + DE VRL + + +++ L ++P + + AE
Sbjct: 206 KVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAE 265
Query: 416 DTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
D WRVR + + L +G + L + L D +R AA +K+L E
Sbjct: 266 DKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENL 325
Query: 476 GPQWAE----NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMA 531
+ E N ++P + + + N + I LS + GK+ T LLP L+
Sbjct: 326 PIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQL 385
Query: 532 DDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIAG 590
D +VR N+ L + + + + + P + +L D V+ E + +AG
Sbjct: 386 KDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 444
>AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2
subunit A isoform beta protein.
Length = 601
Score = 854 bits (2113), Expect = 0.0
Identities = 420/588 (71%), Positives = 485/588 (82%), Gaps = 1/588 (0%)
Query: 2 AASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETI 61
AA G D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+TI
Sbjct: 13 AAGGDG-DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTI 71
Query: 62 YDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHH 121
YDEDEVLLALAEQLG+F LVGG +FAHCLLPPLE LA VEETVVRDKAV SLR +++ H
Sbjct: 72 YDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH 131
Query: 122 SPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTP 181
+P ALE +FVPLV+RLA GDWFTSRTSACGLFSVCYPR S VKAE+RQ FRSLC DDTP
Sbjct: 132 TPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTP 191
Query: 182 MVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPED 241
MVRRAAA KLGEFAKV+E++ VKS+++P+F LA D+QDSVR + +D
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 242 MEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVR 301
+E VMPT+R + D SWRVRYMVAD+F ELQ+A+G ++ DL FQ LLKD EAEVR
Sbjct: 252 LETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVR 311
Query: 302 AAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQ 361
AAAA KVK+ NL +E IIM ILP IK+LV D NQHVKSALASVIMGLS I+G++
Sbjct: 312 AAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKE 371
Query: 362 NTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRV 421
NTIEHLLPLFL QLKDECP+VRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWRV
Sbjct: 372 NTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRV 431
Query: 422 RLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAE 481
RLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NL KLV+++G +WA+
Sbjct: 432 RLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQ 491
Query: 482 NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFN 541
N ++PKVL M+++ NYLHRMT LFCIN LSE CG++ITT+ +LP VL MA D VANVRFN
Sbjct: 492 NTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFN 551
Query: 542 VAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
VAK+LQ + LD +Q +VKPVL+KL D D+DVKYFA EAI+ +A
Sbjct: 552 VAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLA 599
Score = 87.8 bits (208), Expect = 9e-17
Identities = 91/419 (21%), Positives = 166/419 (39%), Gaps = 12/419 (2%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P F+ D+D V
Sbjct: 33 RNEDVQLRLNSIKKLSTIALALGVERTRSELLP-FLTDTIYDEDEVLLALAEQLGNFTGL 91
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKD- 295
D ++P + L+ VR DK VE + + QE L F L+K
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVR----DKAVESLRQISQEHTPVALEAYFVPLVKRL 147
Query: 296 SEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLS 355
+ + + F + +A + + I Q + L D V+ A AS + +
Sbjct: 148 ASGDWFTSRTSACGLFSVCYPRA--SNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFA 205
Query: 356 PIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
++ + ++PLF + DE VRL + + +++ L ++P + + AE
Sbjct: 206 KVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAE 265
Query: 416 DTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
D WRVR + + L +G + L + L D +R AA +K+L E
Sbjct: 266 DKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENL 325
Query: 476 GPQWAE----NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMA 531
+ E N ++P + + + N + I LS + GK+ T LLP L+
Sbjct: 326 PIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQL 385
Query: 532 DDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIAG 590
D +VR N+ L + + + + + P + +L D V+ E + +AG
Sbjct: 386 KDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 444
>AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A beta isoform protein.
Length = 601
Score = 853 bits (2110), Expect = 0.0
Identities = 420/588 (71%), Positives = 484/588 (82%), Gaps = 1/588 (0%)
Query: 2 AASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETI 61
AA G D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+TI
Sbjct: 13 AAGGDG-DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTI 71
Query: 62 YDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHH 121
YDEDEVLLALAEQLG+F LVGG +FAHCLLPPLE LA VEETVVRDKAV SLR +++ H
Sbjct: 72 YDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH 131
Query: 122 SPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTP 181
+P ALE +FVPLV+RLA GDWFTSRTSACGLFSVCYPR S VKAE RQ FRSLC DDTP
Sbjct: 132 TPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAETRQQFRSLCSDDTP 191
Query: 182 MVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPED 241
MVRRAAA KLGEFAKV+E++ VKS+++P+F LA D+QDSVR + +D
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 242 MEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVR 301
+E VMPT+R + D SWRVRYMVAD+F ELQ+A+G ++ DL FQ LLKD EAEVR
Sbjct: 252 LETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVR 311
Query: 302 AAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQ 361
AAAA KVK+ NL +E IIM ILP IK+LV D NQHVKSALASVIMGLS I+G++
Sbjct: 312 AAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKE 371
Query: 362 NTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRV 421
NTIEHLLPLFL QLKDECP+VRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWRV
Sbjct: 372 NTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRV 431
Query: 422 RLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAE 481
RLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NL KLV+++G +WA+
Sbjct: 432 RLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQ 491
Query: 482 NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFN 541
N ++PKVL M+++ NYLHRMT LFCIN LSE CG++ITT+ +LP VL MA D VANVRFN
Sbjct: 492 NTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFN 551
Query: 542 VAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
VAK+LQ + LD +Q +VKPVL+KL D D+DVKYFA EAI+ +A
Sbjct: 552 VAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLA 599
Score = 85.8 bits (203), Expect = 4e-16
Identities = 90/419 (21%), Positives = 165/419 (39%), Gaps = 12/419 (2%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P F+ D+D V
Sbjct: 33 RNEDVQLRLNSIKKLSTIALALGVERTRSELLP-FLTDTIYDEDEVLLALAEQLGNFTGL 91
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKD- 295
D ++P + L+ VR DK VE + + QE L F L+K
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVR----DKAVESLRQISQEHTPVALEAYFVPLVKRL 147
Query: 296 SEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLS 355
+ + + F + +A + + Q + L D V+ A AS + +
Sbjct: 148 ASGDWFTSRTSACGLFSVCYPRA--SNAVKAETRQQFRSLCSDDTPMVRRAAASKLGEFA 205
Query: 356 PIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
++ + ++PLF + DE VRL + + +++ L ++P + + AE
Sbjct: 206 KVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAE 265
Query: 416 DTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
D WRVR + + L +G + L + L D +R AA +K+L E
Sbjct: 266 DKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENL 325
Query: 476 GPQWAE----NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMA 531
+ E N ++P + + + N + I LS + GK+ T LLP L+
Sbjct: 326 PIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQL 385
Query: 532 DDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIAG 590
D +VR N+ L + + + + + P + +L D V+ E + +AG
Sbjct: 386 KDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 444
>AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A, beta isoform protein.
Length = 601
Score = 853 bits (2110), Expect = 0.0
Identities = 420/588 (71%), Positives = 484/588 (82%), Gaps = 1/588 (0%)
Query: 2 AASDSGTDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETI 61
AA G D+SLYPIAVLIDEL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+TI
Sbjct: 13 AAGGDG-DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTI 71
Query: 62 YDEDEVLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHH 121
YDEDEVLLALAEQLG+F LVGG +FAHCLLPPLE LA VEETVVRDKAV SLR +++ H
Sbjct: 72 YDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEH 131
Query: 122 SPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTP 181
+P ALE +FVPLV+RLA GDWFTSRTSACGLFSVCYPR S VKAE RQ FRSLC DDTP
Sbjct: 132 TPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAETRQQFRSLCSDDTP 191
Query: 182 MVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPED 241
MVRRAAA KLGEFAKV+E++ VKS+++P+F LA D+QDSVR + +D
Sbjct: 192 MVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDD 251
Query: 242 MEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVR 301
+E VMPT+R + D SWRVRYMVAD+F ELQ+A+G ++ DL FQ LLKD EAEVR
Sbjct: 252 LETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVR 311
Query: 302 AAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQ 361
AAAA KVK+ NL +E IIM ILP IK+LV D NQHVKSALASVIMGLS I+G++
Sbjct: 312 AAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKE 371
Query: 362 NTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRV 421
NTIEHLLPLFL QLKDECP+VRLNIISNL+CVNEVIGI+QL QSLLPAIVELAED KWRV
Sbjct: 372 NTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRV 431
Query: 422 RLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAE 481
RLAIIE+MPLLAGQLG EFFDEKL SLCM+WLVDHVYAIREAAT NL KLV+++G +WA+
Sbjct: 432 RLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQ 491
Query: 482 NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFN 541
N ++PKVL M+++ NYLHRMT LFCIN LSE CG++ITT+ +LP VL MA D VANVRFN
Sbjct: 492 NTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFN 551
Query: 542 VAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
VAK+LQ + LD +Q +VKPVL+KL D D+DVKYFA EAI+ +A
Sbjct: 552 VAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLA 599
Score = 85.8 bits (203), Expect = 4e-16
Identities = 90/419 (21%), Positives = 165/419 (39%), Gaps = 12/419 (2%)
Query: 177 QDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXX 236
+++ +R + KL A + +E +S+L+P F+ D+D V
Sbjct: 33 RNEDVQLRLNSIKKLSTIALALGVERTRSELLP-FLTDTIYDEDEVLLALAEQLGNFTGL 91
Query: 237 XTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKD- 295
D ++P + L+ VR DK VE + + QE L F L+K
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVR----DKAVESLRQISQEHTPVALEAYFVPLVKRL 147
Query: 296 SEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLS 355
+ + + F + +A + + Q + L D V+ A AS + +
Sbjct: 148 ASGDWFTSRTSACGLFSVCYPRA--SNAVKAETRQQFRSLCSDDTPMVRRAAASKLGEFA 205
Query: 356 PIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
++ + ++PLF + DE VRL + + +++ L ++P + + AE
Sbjct: 206 KVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAE 265
Query: 416 DTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
D WRVR + + L +G + L + L D +R AA +K+L E
Sbjct: 266 DKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENL 325
Query: 476 GPQWAE----NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMA 531
+ E N ++P + + + N + I LS + GK+ T LLP L+
Sbjct: 326 PIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQL 385
Query: 532 DDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIAG 590
D +VR N+ L + + + + + P + +L D V+ E + +AG
Sbjct: 386 KDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAG 444
>M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A
regulatory subunit-beta protein.
Length = 575
Score = 825 bits (2041), Expect = 0.0
Identities = 404/569 (71%), Positives = 468/569 (82%)
Query: 21 ELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETIYDEDEVLLALAEQLGSFIN 80
EL+NEDVQLRLNSIKKLSTIALALGVERT+SEL+PFLT+TIYD DEVLLALAEQLG+F
Sbjct: 5 ELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDVDEVLLALAEQLGNFTG 64
Query: 81 LVGGGEFAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGG 140
LVGG +FAHCLLPPLE LA VEETVVRDKAV SLR +++ H+P ALE +FVPLV+RLA G
Sbjct: 65 LVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASG 124
Query: 141 DWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEI 200
DWFTSRTSACGLFSVCYPR S VKAE RQ FRSLC DDTPMVRRAAA KLGEFAKV+E+
Sbjct: 125 DWFTSRTSACGLFSVCYPRASNAVKAETRQQFRSLCSDDTPMVRRAAASKLGEFAKVLEL 184
Query: 201 EYVKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWR 260
+ VKS+++P+F LA D+QDSVR + +D+E VMPT+R + D SWR
Sbjct: 185 DSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWR 244
Query: 261 VRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQ 320
VRYMVAD+F ELQ+A+G ++ DL FQ LLKD EAEVRAAAA KVK+ NL +
Sbjct: 245 VRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDR 304
Query: 321 EHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECP 380
E IIM ILP IK+LV D NQHVKSALASVIMGLS I+G++NTIEHLLPLFL QLKDECP
Sbjct: 305 ETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECP 364
Query: 381 EVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEF 440
+VRLNIISNL+CVNEVIGI++L QSLLPAIVELAED KWRVRLAIIE+MPLLAGQLG EF
Sbjct: 365 DVRLNIISNLDCVNEVIGIRRLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEF 424
Query: 441 FDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHR 500
FDEKL SLCM+WLVDHVYAIREAAT NL KLV+++G +WA+N ++PKVL M+++ NYLHR
Sbjct: 425 FDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHR 484
Query: 501 MTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQP 560
MT LFCIN LSE CG++ITT+ +LP VL MA D VANVRFNVAK+LQ + LD +Q
Sbjct: 485 MTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQG 544
Query: 561 QVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
+VKPVL+KL D D+DVKYFA EAI+ +A
Sbjct: 545 EVKPVLQKLGQDEDMDVKYFAQEAISVLA 573
Score = 86.2 bits (204), Expect = 3e-16
Identities = 92/424 (21%), Positives = 166/424 (39%), Gaps = 12/424 (2%)
Query: 172 FRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXXXXXX 231
FR +++ +R + KL A + +E +S+L+P F+ D D V
Sbjct: 2 FRPELRNEDVQLRLNSIKKLSTIALALGVERTRSELLP-FLTDTIYDVDEVLLALAEQLG 60
Query: 232 XXXXXXTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQA 291
D ++P + L+ VR DK VE + + QE L F
Sbjct: 61 NFTGLVGGPDFAHCLLPPLENLATVEETVVR----DKAVESLRQISQEHTPVALEAYFVP 116
Query: 292 LLKD-SEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASV 350
L+K + + + F + +A + + Q + L D V+ A AS
Sbjct: 117 LVKRLASGDWFTSRTSACGLFSVCYPRA--SNAVKAETRQQFRSLCSDDTPMVRRAAASK 174
Query: 351 IMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAI 410
+ + ++ + ++PLF + DE VRL + + +++ L ++P +
Sbjct: 175 LGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTL 234
Query: 411 VELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYAIREAATLNLKK 470
+ AED WRVR + + L +G + L + L D +R AA +K+
Sbjct: 235 RQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKE 294
Query: 471 LVEQYGPQWAE----NNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPT 526
L E + E N ++P + + + N + I LS + GK+ T LLP
Sbjct: 295 LGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPL 354
Query: 527 VLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYFASEAIA 586
L+ D +VR N+ L + + + + + P + +L D V+ E +
Sbjct: 355 FLAQLKDECPDVRLNIISNLDCVNEVIGIRRLSQSLLPAIVELAEDAKWRVRLAIIEYMP 414
Query: 587 GIAG 590
+AG
Sbjct: 415 LLAG 418
Score = 40.7 bits (91), Expect = 0.014
Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 12/222 (5%)
Query: 8 TDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETIYDED-E 66
T E L P+ + +LK+E +RLN I L + +G+ R L+P + E D
Sbjct: 347 TIEHLLPL--FLAQLKDECPDVRLNIISNLDCVNEVIGIRRLSQSLLPAIVELAEDAKWR 404
Query: 67 VLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEET-VVRDKAVASLRAVAEHHSPQA 125
V LA+ E + + G EF L L V+ +R+ A +L + + +
Sbjct: 405 VRLAIIEYMPLLAGQL-GVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEW 463
Query: 126 LEEHFVPLVQRLAGGDWFTSR--TSAC--GLFSVCYPRVSAPVKAELRQHFRSLCQDDTP 181
+ VP V +A + R T C L C ++ ++ + D
Sbjct: 464 AQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITT---KQMLPIVLKMAGDQVA 520
Query: 182 MVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVR 223
VR A L + +++ ++ ++ P+ L +D+ V+
Sbjct: 521 NVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVK 562
>AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ34068 fis, clone FCBBF3001918, highly similar to
SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA
REGULATORY ).
Length = 509
Score = 646 bits (1596), Expect = 0.0
Identities = 317/441 (71%), Positives = 363/441 (82%)
Query: 145 SRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVK 204
S +ACGLFSVCYPRVS+ VKAELRQ+FR+LC DDTPMVRRAAA KLGEFAKV+E++ VK
Sbjct: 63 STCTACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVK 122
Query: 205 SDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVRYM 264
S++IP+F LA D+QDSVR ED+E VMPT+R + D SWRVRYM
Sbjct: 123 SEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYM 182
Query: 265 VADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEHII 324
VADKF ELQ+AVG E+ +TDL FQ L+KD EAEVRAAA+ KVK+FC NL +E++I
Sbjct: 183 VADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVI 242
Query: 325 MTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRL 384
M+ ILP IK+LV DANQHVKSALASVIMGLSPI+G+ NTIEHLLPLFL QLKDECPEVRL
Sbjct: 243 MSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRL 302
Query: 385 NIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEK 444
NIISNL+CVNEVIGI+QL QSLLPAIVELAED KWRVRLAIIE+MPLLAGQLG EFFDEK
Sbjct: 303 NIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEK 362
Query: 445 LTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYL 504
L SLCM+WLVDHVYAIREAAT NLKKLVE++G +WA +IPKVL MS + NYLHRMT L
Sbjct: 363 LNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTL 422
Query: 505 FCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKP 564
FCINVLSEVCG+DITT+ +LPTVL MA D VANVRFNVAK+LQ + LD + +Q +VKP
Sbjct: 423 FCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKP 482
Query: 565 VLEKLNVDPDVDVKYFASEAI 585
+LEKL D DVDVKYFA EA+
Sbjct: 483 ILEKLTQDQDVDVKYFAQEAL 503
Score = 93.1 bits (221), Expect = 2e-18
Identities = 90/411 (21%), Positives = 161/411 (39%), Gaps = 10/411 (2%)
Query: 29 LRLNSIKKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINLVGGGEF 87
+R + KL A L ++ KSE+IP + DE D V L E + L+ +
Sbjct: 101 VRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDL 160
Query: 88 AHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRT 147
++P L A + VR + + P+ + VP Q L R
Sbjct: 161 EALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRA 220
Query: 148 SACGLFSVCYPRVSAP-----VKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEY 202
+A +SA + +++ + L D V+ A A + + ++ +
Sbjct: 221 AASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDN 280
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
L+P+F+ +D+ VR + Q ++P + L+ DA WRVR
Sbjct: 281 TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVR 340
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + L +G E L + A L D +R AA +K ++K +E
Sbjct: 341 LAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL---VEKFGKEW 397
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEV 382
T I+P++ + D N + I LS + G+ T +H+LP L D V
Sbjct: 398 AHAT-IIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV 456
Query: 383 RLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
R N+ +L+ + ++ L + P + +L +D V+ E + +L+
Sbjct: 457 RFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS 507
Score = 80.2 bits (189), Expect = 2e-14
Identities = 60/262 (22%), Positives = 108/262 (41%), Gaps = 4/262 (1%)
Query: 333 KDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLEC 392
++L D V+ A AS + + ++ N ++P+F DE VRL +
Sbjct: 91 RNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVN 150
Query: 393 VNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSW 452
+ +++ + L ++P + + AED WRVR + + L +G E L +
Sbjct: 151 IAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNL 210
Query: 453 LVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMTYLFCIN 508
+ D +R AA+ +K+ E EN ++P + + + N + I
Sbjct: 211 MKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIM 270
Query: 509 VLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEK 568
LS + GKD T LLP L+ D VR N+ L + + + + + P + +
Sbjct: 271 GLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVE 330
Query: 569 LNVDPDVDVKYFASEAIAGIAG 590
L D V+ E + +AG
Sbjct: 331 LAEDAKWRVRLAIIEYMPLLAG 352
Score = 76.6 bits (180), Expect = 2e-13
Identities = 76/390 (19%), Positives = 155/390 (39%), Gaps = 8/390 (2%)
Query: 203 VKSDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVR 262
VK++L F L DD VR ++++ ++P L+ D VR
Sbjct: 82 VKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVR 141
Query: 263 YMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH 322
+ + V + Q + QE + + +D VR A K + L KA
Sbjct: 142 LLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTE----LQKAVGPE 197
Query: 323 IIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVG---RQNTI-EHLLPLFLTQLKDE 378
I T ++P ++L+ D V++A + + + R+N I +LP + D
Sbjct: 198 ITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDA 257
Query: 379 CPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQ 438
V+ + S + ++ ++G ++ LLP + +D VRL II ++ + +G
Sbjct: 258 NQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGI 317
Query: 439 EFFDEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYL 498
+ L + D + +R A + L Q G ++ + + + + Y
Sbjct: 318 RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYA 377
Query: 499 HRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVI 558
R + L E GK+ ++P VL+M+ D R + ++++ +
Sbjct: 378 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 437
Query: 559 QPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
+ P + ++ DP +V++ ++++ I
Sbjct: 438 TKHMLPTVLRMAGDPVANVRFNVAKSLQKI 467
Score = 65.7 bits (153), Expect = 4e-10
Identities = 88/428 (20%), Positives = 173/428 (40%), Gaps = 16/428 (3%)
Query: 50 KSELIPFLTETIYDEDEVLL-ALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEETVVRD 108
K+EL + D+ ++ A A +LG F ++ ++P LA+ E+ VR
Sbjct: 83 KAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRL 142
Query: 109 KAVASLRAVAEHHSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPV-KAE 167
AV + +A+ + LE +P +++ A + R F+ V + K +
Sbjct: 143 LAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTD 202
Query: 168 LRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIE----YVKSDLIPIFVILAEDDQDSVR 223
L F++L +D VR AA++K+ EF + + + + S ++P L D V+
Sbjct: 203 LVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVK 262
Query: 224 XXXXXXXXXXXXXXTPEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQAVG-QELAR 282
++ +H++P A D VR + + + +G ++L++
Sbjct: 263 SALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQ 322
Query: 283 TDLAQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQH 342
+ L I + L +D++ VR A + L + + ++ + + D V
Sbjct: 323 SLLPAIVE-LAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHV----YA 377
Query: 343 VKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQL 402
++ A S + L G++ ++P L D R+ + + ++EV G
Sbjct: 378 IREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDIT 437
Query: 403 VQSLLPAIVELAEDTKWRVRLAIIEHM----PLLAGQLGQEFFDEKLTSLCMSWLVDHVY 458
+ +LP ++ +A D VR + + + P+L Q L L VD Y
Sbjct: 438 TKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKY 497
Query: 459 AIREAATL 466
+EA T+
Sbjct: 498 FAQEALTV 505
Score = 44.4 bits (100), Expect = 0.001
Identities = 47/219 (21%), Positives = 90/219 (41%), Gaps = 6/219 (2%)
Query: 8 TDESLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGVERTKSELIPFLTETIYDED-E 66
T E L P+ + +LK+E ++RLN I L + +G+ + L+P + E D
Sbjct: 281 TIEHLLPL--FLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWR 338
Query: 67 VLLALAEQLGSFINLVGGGEFAHCLLPPLETLAAVEET-VVRDKAVASLRAVAEHHSPQA 125
V LA+ E + + G EF L L V+ +R+ A ++L+ + E +
Sbjct: 339 VRLAIIEYMPLLAGQL-GVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEW 397
Query: 126 LEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAE-LRQHFRSLCQDDTPMVR 184
+P V ++G + R + +V + + + + D VR
Sbjct: 398 AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVR 457
Query: 185 RAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVR 223
A L + +++ ++S++ PI L +D V+
Sbjct: 458 FNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVK 496
>BC060829-1|AAH60829.1| 933|Homo sapiens protein phosphatase 4,
regulatory subunit 1 protein.
Length = 933
Score = 74.9 bits (176), Expect = 7e-13
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 14/261 (5%)
Query: 335 LVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVN 394
L D V+ LA I L+ I+G Q T L+P+F LKD EVR+ ++ +L
Sbjct: 654 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFL 712
Query: 395 EVIGIQQLVQSLLPAIVELAEDTK--WRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSW 452
+++ I + + L L D WR R + E + LL + L + ++
Sbjct: 713 KLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNL 772
Query: 453 LVDHVYAIR----EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLF-CI 507
D V ++R + + +KKL P + + + V N + R ++F C
Sbjct: 773 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 832
Query: 508 NVLSEVC-GKDITTRVLLPTVLSMADDNVANVRFNVAKTLQ--IMAK--YLDPAVI-QPQ 561
V+ + C D L+P +L++A+D V NVR +AKTL+ ++ K +L A Q
Sbjct: 833 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 892
Query: 562 VKPVLEKLNVDPDVDVKYFAS 582
V+ + L +D D DVKYFAS
Sbjct: 893 VEQTIMALQMDRDSDVKYFAS 913
Score = 57.6 bits (133), Expect = 1e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 324 IMTMILPQIKDLVC-DANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPE 381
+ T + P + +L D+N VK+ +++ ++P+VG+ T +LP F D
Sbjct: 152 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFH 211
Query: 382 VRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFF 441
VR +N + V+G Q + LLP +L D W VR A E ++ QE
Sbjct: 212 VRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIR 271
Query: 442 DEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
KL++L ++ + D +R+AA +L + +
Sbjct: 272 RTKLSALFINLISDPSRWVRQAAFQSLGPFISTF 305
Score = 48.0 bits (109), Expect = 9e-05
Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 249 TVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKV 308
T L+ D W+VR +A EL +G +L DL IF LKD + EVR +
Sbjct: 650 TYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHL 708
Query: 309 KDF--CMNLDKAHQEHIIMTMILPQIKD-LVCD--ANQHVKSALASVIMGLSPIVGRQNT 363
DF +++DK + L Q+++ LV D N ++ LA ++ L + ++
Sbjct: 709 HDFLKLLHIDKRRE-------YLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDV 761
Query: 364 IEHLLPLFLTQLKDECPEVR 383
++L P+ L D+ VR
Sbjct: 762 YDYLRPIALNLCADKVSSVR 781
Score = 39.9 bits (89), Expect = 0.025
Identities = 49/227 (21%), Positives = 83/227 (36%), Gaps = 5/227 (2%)
Query: 168 LRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXX 227
LR+ + +L D VRR A+ + E A ++ + +DL+PIF + D D VR
Sbjct: 647 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLK-DLDEVRIGVL 705
Query: 228 XXXXXXXXXXTPEDMEQHVMPTVRALSGDAS--WRVRYMVADKFVELQQAVGQELARTDL 285
+ +++ L D S WR R +A++ + L + L
Sbjct: 706 KHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYL 765
Query: 286 AQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKS 345
I L D + VR + V + L A + +I +++ +
Sbjct: 766 RPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQ 825
Query: 346 ALASVIMGL--SPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNL 390
A V + + HL+P LT D P VR+ + L
Sbjct: 826 AFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 872
Score = 38.7 bits (86), Expect = 0.057
Identities = 22/62 (35%), Positives = 32/62 (51%)
Query: 243 EQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRA 302
E+ ++P L D W VR A+ F+ + A QE+ RT L+ +F L+ D VR
Sbjct: 233 EEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQ 292
Query: 303 AA 304
AA
Sbjct: 293 AA 294
Score = 32.3 bits (70), Expect = 4.9
Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 6/185 (3%)
Query: 406 LLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLV----DHVYAIR 461
LLP +V D +VR + L Q E FD + T +C + D ++
Sbjct: 115 LLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVK 173
Query: 462 EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLH-RMTYLFCINVLSEVCGKDITT 520
A + K+ G E ++P+ M + H R + V G+ T
Sbjct: 174 TEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATE 233
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYF 580
+LLP + DNV VR A+ ++ + + ++ + L DP V+
Sbjct: 234 EMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQA 293
Query: 581 ASEAI 585
A +++
Sbjct: 294 AFQSL 298
Score = 31.9 bits (69), Expect = 6.5
Identities = 36/142 (25%), Positives = 56/142 (39%), Gaps = 5/142 (3%)
Query: 87 FAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQA--LEEHFVPLVQRLAGGDWFT 144
F+ LLP + A + VR + A+L A+ E + +E P++ L D
Sbjct: 111 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND 170
Query: 145 S-RTSACGLFSVCYPRVSAPVKAEL-RQHFRSLCQDDTPM-VRRAAAYKLGEFAKVVEIE 201
+T A + P V + L F +C D VR+ A G+ VV +
Sbjct: 171 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ 230
Query: 202 YVKSDLIPIFVILAEDDQDSVR 223
+ L+P F L D+ VR
Sbjct: 231 ATEEMLLPRFFQLCSDNVWGVR 252
>AF200478-1|AAL78298.1| 950|Homo sapiens protein serine/threonine
phosphatase 4 subunit PP4Rmeg protein.
Length = 950
Score = 74.9 bits (176), Expect = 7e-13
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 14/261 (5%)
Query: 335 LVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVN 394
L D V+ LA I L+ I+G Q T L+P+F LKD EVR+ ++ +L
Sbjct: 671 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFL 729
Query: 395 EVIGIQQLVQSLLPAIVELAEDTK--WRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSW 452
+++ I + + L L D WR R + E + LL + L + ++
Sbjct: 730 KLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNL 789
Query: 453 LVDHVYAIR----EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLF-CI 507
D V ++R + + +KKL P + + + V N + R ++F C
Sbjct: 790 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 849
Query: 508 NVLSEVC-GKDITTRVLLPTVLSMADDNVANVRFNVAKTLQ--IMAK--YLDPAVI-QPQ 561
V+ + C D L+P +L++A+D V NVR +AKTL+ ++ K +L A Q
Sbjct: 850 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 909
Query: 562 VKPVLEKLNVDPDVDVKYFAS 582
V+ + L +D D DVKYFAS
Sbjct: 910 VEQTIMALQMDRDSDVKYFAS 930
Score = 57.6 bits (133), Expect = 1e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 324 IMTMILPQIKDLVC-DANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPE 381
+ T + P + +L D+N VK+ +++ ++P+VG+ T +LP F D
Sbjct: 169 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFH 228
Query: 382 VRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFF 441
VR +N + V+G Q + LLP +L D W VR A E ++ QE
Sbjct: 229 VRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIR 288
Query: 442 DEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
KL++L ++ + D +R+AA +L + +
Sbjct: 289 RTKLSALFINLISDPSRWVRQAAFQSLGPFISTF 322
Score = 48.0 bits (109), Expect = 9e-05
Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 249 TVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKV 308
T L+ D W+VR +A EL +G +L DL IF LKD + EVR +
Sbjct: 667 TYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHL 725
Query: 309 KDF--CMNLDKAHQEHIIMTMILPQIKD-LVCD--ANQHVKSALASVIMGLSPIVGRQNT 363
DF +++DK + L Q+++ LV D N ++ LA ++ L + ++
Sbjct: 726 HDFLKLLHIDKRRE-------YLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDV 778
Query: 364 IEHLLPLFLTQLKDECPEVR 383
++L P+ L D+ VR
Sbjct: 779 YDYLRPIALNLCADKVSSVR 798
Score = 39.9 bits (89), Expect = 0.025
Identities = 49/227 (21%), Positives = 83/227 (36%), Gaps = 5/227 (2%)
Query: 168 LRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXX 227
LR+ + +L D VRR A+ + E A ++ + +DL+PIF + D D VR
Sbjct: 664 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLK-DLDEVRIGVL 722
Query: 228 XXXXXXXXXXTPEDMEQHVMPTVRALSGDAS--WRVRYMVADKFVELQQAVGQELARTDL 285
+ +++ L D S WR R +A++ + L + L
Sbjct: 723 KHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYL 782
Query: 286 AQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKS 345
I L D + VR + V + L A + +I +++ +
Sbjct: 783 RPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQ 842
Query: 346 ALASVIMGL--SPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNL 390
A V + + HL+P LT D P VR+ + L
Sbjct: 843 AFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 889
Score = 38.7 bits (86), Expect = 0.057
Identities = 22/62 (35%), Positives = 32/62 (51%)
Query: 243 EQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRA 302
E+ ++P L D W VR A+ F+ + A QE+ RT L+ +F L+ D VR
Sbjct: 250 EEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQ 309
Query: 303 AA 304
AA
Sbjct: 310 AA 311
Score = 32.3 bits (70), Expect = 4.9
Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 6/185 (3%)
Query: 406 LLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLV----DHVYAIR 461
LLP +V D +VR + L Q E FD + T +C + D ++
Sbjct: 132 LLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVK 190
Query: 462 EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLH-RMTYLFCINVLSEVCGKDITT 520
A + K+ G E ++P+ M + H R + V G+ T
Sbjct: 191 TEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATE 250
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYF 580
+LLP + DNV VR A+ ++ + + ++ + L DP V+
Sbjct: 251 EMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQA 310
Query: 581 ASEAI 585
A +++
Sbjct: 311 AFQSL 315
Score = 31.9 bits (69), Expect = 6.5
Identities = 36/142 (25%), Positives = 56/142 (39%), Gaps = 5/142 (3%)
Query: 87 FAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQA--LEEHFVPLVQRLAGGDWFT 144
F+ LLP + A + VR + A+L A+ E + +E P++ L D
Sbjct: 128 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND 187
Query: 145 S-RTSACGLFSVCYPRVSAPVKAEL-RQHFRSLCQDDTPM-VRRAAAYKLGEFAKVVEIE 201
+T A + P V + L F +C D VR+ A G+ VV +
Sbjct: 188 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ 247
Query: 202 YVKSDLIPIFVILAEDDQDSVR 223
+ L+P F L D+ VR
Sbjct: 248 ATEEMLLPRFFQLCSDNVWGVR 269
>AF111106-1|AAD09818.1| 933|Homo sapiens protein serine/threonine
phosphatase 4 regulatory subunit 1 protein.
Length = 933
Score = 74.9 bits (176), Expect = 7e-13
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 14/261 (5%)
Query: 335 LVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVN 394
L D V+ LA I L+ I+G Q T L+P+F LKD EVR+ ++ +L
Sbjct: 654 LASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFL 712
Query: 395 EVIGIQQLVQSLLPAIVELAEDTK--WRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSW 452
+++ I + + L L D WR R + E + LL + L + ++
Sbjct: 713 KLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNL 772
Query: 453 LVDHVYAIR----EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLF-CI 507
D V ++R + + +KKL P + + + V N + R ++F C
Sbjct: 773 CADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQ 832
Query: 508 NVLSEVC-GKDITTRVLLPTVLSMADDNVANVRFNVAKTLQ--IMAK--YLDPAVI-QPQ 561
V+ + C D L+P +L++A+D V NVR +AKTL+ ++ K +L A Q
Sbjct: 833 TVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEA 892
Query: 562 VKPVLEKLNVDPDVDVKYFAS 582
V+ + L +D D DVKYFAS
Sbjct: 893 VEQTIMALQMDRDSDVKYFAS 913
Score = 57.6 bits (133), Expect = 1e-07
Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 324 IMTMILPQIKDLVC-DANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPE 381
+ T + P + +L D+N VK+ +++ ++P+VG+ T +LP F D
Sbjct: 152 VETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFH 211
Query: 382 VRLNIISNLECVNEVIGIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFF 441
VR +N + V+G Q + LLP +L D W VR A E ++ QE
Sbjct: 212 VRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIR 271
Query: 442 DEKLTSLCMSWLVDHVYAIREAATLNLKKLVEQY 475
KL++L ++ + D +R+AA +L + +
Sbjct: 272 RTKLSALFINLISDPSRWVRQAAFQSLGPFISTF 305
Score = 48.0 bits (109), Expect = 9e-05
Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 249 TVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKV 308
T L+ D W+VR +A EL +G +L DL IF LKD + EVR +
Sbjct: 650 TYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLKHL 708
Query: 309 KDF--CMNLDKAHQEHIIMTMILPQIKD-LVCD--ANQHVKSALASVIMGLSPIVGRQNT 363
DF +++DK + L Q+++ LV D N ++ LA ++ L + ++
Sbjct: 709 HDFLKLLHIDKRRE-------YLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDV 761
Query: 364 IEHLLPLFLTQLKDECPEVR 383
++L P+ L D+ VR
Sbjct: 762 YDYLRPIALNLCADKVSSVR 781
Score = 39.9 bits (89), Expect = 0.025
Identities = 49/227 (21%), Positives = 83/227 (36%), Gaps = 5/227 (2%)
Query: 168 LRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXX 227
LR+ + +L D VRR A+ + E A ++ + +DL+PIF + D D VR
Sbjct: 647 LRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLK-DLDEVRIGVL 705
Query: 228 XXXXXXXXXXTPEDMEQHVMPTVRALSGDAS--WRVRYMVADKFVELQQAVGQELARTDL 285
+ +++ L D S WR R +A++ + L + L
Sbjct: 706 KHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYL 765
Query: 286 AQIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKS 345
I L D + VR + V + L A + +I +++ +
Sbjct: 766 RPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQ 825
Query: 346 ALASVIMGL--SPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNL 390
A V + + HL+P LT D P VR+ + L
Sbjct: 826 AFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 872
Score = 38.7 bits (86), Expect = 0.057
Identities = 22/62 (35%), Positives = 32/62 (51%)
Query: 243 EQHVMPTVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRA 302
E+ ++P L D W VR A+ F+ + A QE+ RT L+ +F L+ D VR
Sbjct: 233 EEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQ 292
Query: 303 AA 304
AA
Sbjct: 293 AA 294
Score = 32.3 bits (70), Expect = 4.9
Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 6/185 (3%)
Query: 406 LLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLV----DHVYAIR 461
LLP +V D +VR + L Q E FD + T +C + D ++
Sbjct: 115 LLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVE-TKVCPVLIELTAPDSNDDVK 173
Query: 462 EAATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLH-RMTYLFCINVLSEVCGKDITT 520
A + K+ G E ++P+ M + H R + V G+ T
Sbjct: 174 TEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATE 233
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDPDVDVKYF 580
+LLP + DNV VR A+ ++ + + ++ + L DP V+
Sbjct: 234 EMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQA 293
Query: 581 ASEAI 585
A +++
Sbjct: 294 AFQSL 298
Score = 31.9 bits (69), Expect = 6.5
Identities = 36/142 (25%), Positives = 56/142 (39%), Gaps = 5/142 (3%)
Query: 87 FAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQA--LEEHFVPLVQRLAGGDWFT 144
F+ LLP + A + VR + A+L A+ E + +E P++ L D
Sbjct: 111 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND 170
Query: 145 S-RTSACGLFSVCYPRVSAPVKAEL-RQHFRSLCQDDTPM-VRRAAAYKLGEFAKVVEIE 201
+T A + P V + L F +C D VR+ A G+ VV +
Sbjct: 171 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ 230
Query: 202 YVKSDLIPIFVILAEDDQDSVR 223
+ L+P F L D+ VR
Sbjct: 231 ATEEMLLPRFFQLCSDNVWGVR 252
>BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein.
Length = 873
Score = 47.6 bits (108), Expect = 1e-04
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 2/168 (1%)
Query: 87 FAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFV-PLVQRLAGGDWFTS 145
+ H L + +T V + + +L +V E + L + PLV + S
Sbjct: 130 YTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQS 189
Query: 146 RTSACGLFSVCYPRVSA-PVKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVK 204
R +C + + A +K E+ +SLCQD VR +L A+ + E K
Sbjct: 190 RLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTK 249
Query: 205 SDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRA 252
S ++P + L+ D+ SVR +D Q ++P V++
Sbjct: 250 SVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKS 297
Score = 40.7 bits (91), Expect = 0.014
Identities = 24/94 (25%), Positives = 41/94 (43%)
Query: 322 HIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPE 381
H I ILP +K L D V+S + + ++ +G + T +LP + +DE
Sbjct: 207 HTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSS 266
Query: 382 VRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
VRL L + ++ Q++LP + E
Sbjct: 267 VRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE 300
Score = 39.5 bits (88), Expect = 0.033
Identities = 53/230 (23%), Positives = 92/230 (40%), Gaps = 11/230 (4%)
Query: 349 SVIMGLSPIVGRQN---TIEHLLPLFLTQLKDECPEVRLNIISNLECV--NEVIGIQQLV 403
SVI L P + RQN T+ +LP L E++L + + +E + I
Sbjct: 73 SVIANL-PFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYT 131
Query: 404 QSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFF-DEKLTSLCMSWLVDHVYAIRE 462
S L I+ E V A +E + + L +E E L L + R
Sbjct: 132 HSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRL 191
Query: 463 AATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRV 522
+ L KL ++ + ++P V ++ + Y R + +++ G ++T V
Sbjct: 192 VSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSV 251
Query: 523 LLPTVLSMADDNVANVRFNVAKTLQIMAKYLD----PAVIQPQVKPVLEK 568
+LP ++ ++ D ++VR +TL + D I P VK EK
Sbjct: 252 VLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEK 301
Score = 36.3 bits (80), Expect = 0.30
Identities = 48/193 (24%), Positives = 81/193 (41%), Gaps = 9/193 (4%)
Query: 239 PEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQ--AVGQELARTDLAQIFQALLKDS 296
P + + V+P VR A ++ A F+ + Q +V Q+ L+
Sbjct: 86 PTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYTHSFLQVILLHLEHR 145
Query: 297 EAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASV-IMGLS 355
+ V A + L K H I+ ++ + + +Q V+S L S I+G
Sbjct: 146 DTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQ-----LSQTVQSRLVSCKILGKL 200
Query: 356 PIVGRQNTIEH-LLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELA 414
+TI+ +LPL + +D EVR + LE + + IG + +LP ++EL+
Sbjct: 201 TNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELS 260
Query: 415 EDTKWRVRLAIIE 427
D VRLA E
Sbjct: 261 RDEGSSVRLAAFE 273
Score = 34.7 bits (76), Expect = 0.93
Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 25 EDVQLRLNSI--KKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINL 81
+DV+ + S ++L IA +G E TKS ++P L E DE V LA E L + +++
Sbjct: 222 QDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
Query: 82 VGGGEFAHCLLPPLETLAAVEETVVRDKAV 111
+ + +LP +++ E++ D+++
Sbjct: 282 FDTDDRSQTILPLVKSFC--EKSFKADESI 309
>AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein.
Length = 892
Score = 47.6 bits (108), Expect = 1e-04
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 2/168 (1%)
Query: 87 FAHCLLPPLETLAAVEETVVRDKAVASLRAVAEHHSPQALEEHFV-PLVQRLAGGDWFTS 145
+ H L + +T V + + +L +V E + L + PLV + S
Sbjct: 149 YTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQS 208
Query: 146 RTSACGLFSVCYPRVSA-PVKAELRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVK 204
R +C + + A +K E+ +SLCQD VR +L A+ + E K
Sbjct: 209 RLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTK 268
Query: 205 SDLIPIFVILAEDDQDSVRXXXXXXXXXXXXXXTPEDMEQHVMPTVRA 252
S ++P + L+ D+ SVR +D Q ++P V++
Sbjct: 269 SVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKS 316
Score = 40.7 bits (91), Expect = 0.014
Identities = 24/94 (25%), Positives = 41/94 (43%)
Query: 322 HIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPE 381
H I ILP +K L D V+S + + ++ +G + T +LP + +DE
Sbjct: 226 HTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSS 285
Query: 382 VRLNIISNLECVNEVIGIQQLVQSLLPAIVELAE 415
VRL L + ++ Q++LP + E
Sbjct: 286 VRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE 319
Score = 39.5 bits (88), Expect = 0.033
Identities = 53/230 (23%), Positives = 92/230 (40%), Gaps = 11/230 (4%)
Query: 349 SVIMGLSPIVGRQN---TIEHLLPLFLTQLKDECPEVRLNIISNLECV--NEVIGIQQLV 403
SVI L P + RQN T+ +LP L E++L + + +E + I
Sbjct: 92 SVIANL-PFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYT 150
Query: 404 QSLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFF-DEKLTSLCMSWLVDHVYAIRE 462
S L I+ E V A +E + + L +E E L L + R
Sbjct: 151 HSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRL 210
Query: 463 AATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRV 522
+ L KL ++ + ++P V ++ + Y R + +++ G ++T V
Sbjct: 211 VSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSV 270
Query: 523 LLPTVLSMADDNVANVRFNVAKTLQIMAKYLD----PAVIQPQVKPVLEK 568
+LP ++ ++ D ++VR +TL + D I P VK EK
Sbjct: 271 VLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEK 320
Score = 36.3 bits (80), Expect = 0.30
Identities = 48/193 (24%), Positives = 81/193 (41%), Gaps = 9/193 (4%)
Query: 239 PEDMEQHVMPTVRALSGDASWRVRYMVADKFVELQQ--AVGQELARTDLAQIFQALLKDS 296
P + + V+P VR A ++ A F+ + Q +V Q+ L+
Sbjct: 105 PTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYTHSFLQVILLHLEHR 164
Query: 297 EAEVRAAAAGKVKDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASV-IMGLS 355
+ V A + L K H I+ ++ + + +Q V+S L S I+G
Sbjct: 165 DTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQ-----LSQTVQSRLVSCKILGKL 219
Query: 356 PIVGRQNTIEH-LLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVELA 414
+TI+ +LPL + +D EVR + LE + + IG + +LP ++EL+
Sbjct: 220 TNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELS 279
Query: 415 EDTKWRVRLAIIE 427
D VRLA E
Sbjct: 280 RDEGSSVRLAAFE 292
Score = 34.7 bits (76), Expect = 0.93
Identities = 25/90 (27%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 25 EDVQLRLNSI--KKLSTIALALGVERTKSELIPFLTETIYDE-DEVLLALAEQLGSFINL 81
+DV+ + S ++L IA +G E TKS ++P L E DE V LA E L + +++
Sbjct: 241 QDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 300
Query: 82 VGGGEFAHCLLPPLETLAAVEETVVRDKAV 111
+ + +LP +++ E++ D+++
Sbjct: 301 FDTDDRSQTILPLVKSFC--EKSFKADESI 328
>U79267-1|AAB50211.1| 173|Homo sapiens unknown protein.
Length = 173
Score = 46.8 bits (106), Expect = 2e-04
Identities = 40/122 (32%), Positives = 62/122 (50%), Gaps = 7/122 (5%)
Query: 468 LKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLF-CINVLSEVC-GKDITTRVLLP 525
+KKL P + + + V N + R ++F C V+ + C D L+P
Sbjct: 32 VKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMP 91
Query: 526 TVLSMADDNVANVRFNVAKTLQ--IMAK--YLDPAVI-QPQVKPVLEKLNVDPDVDVKYF 580
+L++A+D V NVR +AKTL+ ++ K +L A Q V+ + L +D D DVKYF
Sbjct: 92 HLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYF 151
Query: 581 AS 582
AS
Sbjct: 152 AS 153
>AF054284-1|AAC97189.1| 1304|Homo sapiens spliceosomal protein SAP 155
protein.
Length = 1304
Score = 46.0 bits (104), Expect = 4e-04
Identities = 51/228 (22%), Positives = 102/228 (44%), Gaps = 16/228 (7%)
Query: 366 HLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQL---VQSLLPAIVELAEDTKWRVR 422
HL + L +E PEV +I+ L+ + VIG+ ++ ++ LLP + + ++ +V+
Sbjct: 973 HLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQ 1032
Query: 423 LAIIEHMPLLAGQLGQEFFDEKLTSLC---MSWLVDHVYAIREAATLNLKKLVEQYGPQW 479
I+ + +A + + + +C + L H AIR A + + GP
Sbjct: 1033 ENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGP-- 1090
Query: 480 AENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITTRVLLPTVLSMADDNVANVR 539
++V+ +LN Q +R+ I +++E C + +LP +++ NV+
Sbjct: 1091 --HDVLATLLNNLKVQERQNRVCTTVAIAIVAETC----SPFTVLPALMNEYRVPELNVQ 1144
Query: 540 FNVAKTLQIMAKYLDPAVIQ--PQVKPVLEKLNVDPDVDVKYFASEAI 585
V K+L + +Y+ V P+LE +D D+ + AS +
Sbjct: 1145 NGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVV 1192
>AL354776-4|CAM14101.1| 235|Homo sapiens protein phosphatase 4,
regulatory subunit 1-like protein.
Length = 235
Score = 44.8 bits (101), Expect = 9e-04
Identities = 34/135 (25%), Positives = 57/135 (42%), Gaps = 3/135 (2%)
Query: 249 TVRALSGDASWRVRYMVADKFVELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKV 308
T L+ D W+VR +A EL +G +L DL IF LKD + EVR +
Sbjct: 64 TYETLASDVQWKVRRALAFSIHELAVILGDQLTAADLVPIFNGFLKDLD-EVRIGVLRHL 122
Query: 309 KDFCMNLDKAHQEHIIMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLL 368
DF L + + + + + D N + LA ++ + + + ++L+
Sbjct: 123 YDFLKLLHEDKRRDYLYQLQEFVVTD--NSRNWRFRYELAEQLILILELYSPNDVYDYLM 180
Query: 369 PLFLTQLKDECPEVR 383
+ L D+ EVR
Sbjct: 181 HIALKLCADQVSEVR 195
Score = 39.1 bits (87), Expect = 0.043
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 168 LRQHFRSLCQDDTPMVRRAAAYKLGEFAKVVEIEYVKSDLIPIFVILAEDDQDSVRXXXX 227
L+ + +L D VRRA A+ + E A ++ + +DL+PIF + D D VR
Sbjct: 61 LKDTYETLASDVQWKVRRALAFSIHELAVILGDQLTAADLVPIFNGFLK-DLDEVRIGVL 119
Query: 228 XXXXXXXXXXTPEDMEQHVMPTVRALSGDAS--WRVRYMVADKFVELQQAVGQELARTDL 285
+ ++ + D S WR RY +A++ + + + L
Sbjct: 120 RHLYDFLKLLHEDKRRDYLYQLQEFVVTDNSRNWRFRYELAEQLILILELYSPNDVYDYL 179
Query: 286 AQIFQALLKDSEAEVR 301
I L D +EVR
Sbjct: 180 MHIALKLCADQVSEVR 195
>Y08991-1|CAA70176.1| 1358|Homo sapiens adaptor protein protein.
Length = 1358
Score = 37.5 bits (83), Expect = 0.13
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 324 IMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVR 383
++T L +K CD+ K A +I+ L+P + + ++ + P L D P VR
Sbjct: 381 VITSCLQTLK--YCDS----KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVR 434
Query: 384 LNIISNLECVNEVI------GIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
+ L V ++ I + +LP I LA+D VRLA E++ LLA
Sbjct: 435 AEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 490
>BC127106-1|AAI27107.1| 1358|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 4, p150 protein.
Length = 1358
Score = 37.5 bits (83), Expect = 0.13
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 324 IMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVR 383
++T L +K CD+ K A +I+ L+P + + ++ + P L D P VR
Sbjct: 381 VITSCLQTLK--YCDS----KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVR 434
Query: 384 LNIISNLECVNEVI------GIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
+ L V ++ I + +LP I LA+D VRLA E++ LLA
Sbjct: 435 AEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 490
>BC127105-1|AAI27106.1| 1358|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 4, p150 protein.
Length = 1358
Score = 37.5 bits (83), Expect = 0.13
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 324 IMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVR 383
++T L +K CD+ K A +I+ L+P + + ++ + P L D P VR
Sbjct: 381 VITSCLQTLK--YCDS----KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVR 434
Query: 384 LNIISNLECVNEVI------GIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
+ L V ++ I + +LP I LA+D VRLA E++ LLA
Sbjct: 435 AEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 490
>BC110318-1|AAI10319.1| 1358|Homo sapiens phosphoinositide-3-kinase,
regulatory subunit 4, p150 protein.
Length = 1358
Score = 37.5 bits (83), Expect = 0.13
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 324 IMTMILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKDECPEVR 383
++T L +K CD+ K A +I+ L+P + + ++ + P L D P VR
Sbjct: 381 VITSCLQTLK--YCDS----KLAALELILHLAPRLSVEILLDRITPYLLHFSNDSVPRVR 434
Query: 384 LNIISNLECVNEVI------GIQQLVQSLLPAIVELAEDTKWRVRLAIIEHMPLLA 433
+ L V ++ I + +LP I LA+D VRLA E++ LLA
Sbjct: 435 AEALRTLTKVLALVKEVPRNDINIYPEYILPGIAHLAQDDATIVRLAYAENIALLA 490
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 37.1 bits (82), Expect = 0.17
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 37.1 bits (82), Expect = 0.17
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 37.1 bits (82), Expect = 0.17
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 37.1 bits (82), Expect = 0.17
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 37.1 bits (82), Expect = 0.17
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 36.7 bits (81), Expect = 0.23
Identities = 38/153 (24%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQTAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSRA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGIA 589
V+ P+L +P++ +K A+ A++ IA
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKRIAASALSDIA 195
>U88836-1|AAD00655.1| 994|Homo sapiens translational activator GCN1
protein.
Length = 994
Score = 35.9 bits (79), Expect = 0.40
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 328 ILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPEVRLNI 386
++P + +CD + V+ A A L +G Q +E +LP L QL D E E L+
Sbjct: 329 LVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQ-ALEDILPFLLKQLDDEEVSEFALDG 387
Query: 387 ISNLECVNEVIGIQQLVQSL 406
+ + + + + LV L
Sbjct: 388 LKQVMAIKSRVVLPYLVPKL 407
>U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein.
Length = 1928
Score = 35.9 bits (79), Expect = 0.40
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 328 ILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPEVRLNI 386
++P + +CD + V+ A A L +G Q +E +LP L QL D E E L+
Sbjct: 1165 LVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQ-ALEDILPFLLKQLDDEEVSEFALDG 1223
Query: 387 ISNLECVNEVIGIQQLVQSL 406
+ + + + + LV L
Sbjct: 1224 LKQVMAIKSRVVLPYLVPKL 1243
>D86973-1|BAA13209.2| 2675|Homo sapiens KIAA0219 protein.
Length = 2675
Score = 35.9 bits (79), Expect = 0.40
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 328 ILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPEVRLNI 386
++P + +CD + V+ A A L +G Q +E +LP L QL D E E L+
Sbjct: 2010 LVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQ-ALEDILPFLLKQLDDEEVSEFALDG 2068
Query: 387 ISNLECVNEVIGIQQLVQSL 406
+ + + + + LV L
Sbjct: 2069 LKQVMAIKSRVVLPYLVPKL 2088
>BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing 2
protein.
Length = 855
Score = 35.9 bits (79), Expect = 0.40
Identities = 41/165 (24%), Positives = 64/165 (38%), Gaps = 7/165 (4%)
Query: 65 DEVLLALAEQLGSFINLVGGGEFAHC--LLPPLETLAAVEETVVRDKAVASLRAVAE--- 119
+E+ LAL + LG ++L G H L L VR ++ + A+A+
Sbjct: 139 EELRLALVQLLGLAVDLCGAALAPHLDDALRALRCSLLDPFAAVRRESCSCAAALAQATP 198
Query: 120 HHSPQALEEHFVPLVQRLAGGDWFTSRTSACGLFSVCYPRVSAPVKAELRQHFRSLCQDD 179
H E PL+Q ++ W R +A + ++ HF DD
Sbjct: 199 DHFHMQSESLIGPLMQTISHQHWKV-RVAAIEATGAVIHFGNGKSVDDVLSHFAQRLFDD 257
Query: 180 TPMVRRAAAYKLGEFAKVVEIEY-VKSDLIPIFVILAEDDQDSVR 223
P VRRA A +G + + Y LIP+ + D+ VR
Sbjct: 258 VPQVRRAVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVR 302
Score = 34.3 bits (75), Expect = 1.2
Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 328 ILPQIKDLVCDANQHVKSALASVIMG-LSPIVGRQNTIEHLLPLFLTQLKDECPEVR 383
+L + D V+ A+ASV+ G L + R + L+PL L+ L DE PEVR
Sbjct: 246 VLSHFAQRLFDDVPQVRRAVASVVGGWLLCLRDRYSFFHKLIPLLLSSLNDEVPEVR 302
>AC004812-3|AAC83183.1| 2392|Homo sapiens WUGSC:H_267D11.3 protein.
Length = 2392
Score = 35.9 bits (79), Expect = 0.40
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 2/80 (2%)
Query: 328 ILPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLTQLKD-ECPEVRLNI 386
++P + +CD + V+ A A L +G Q +E +LP L QL D E E L+
Sbjct: 1727 LVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQ-ALEDILPFLLKQLDDEEVSEFALDG 1785
Query: 387 ISNLECVNEVIGIQQLVQSL 406
+ + + + + LV L
Sbjct: 1786 LKQVMAIKSRVVLPYLVPKL 1805
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 34.7 bits (76), Expect = 0.93
Identities = 37/152 (24%), Positives = 70/152 (46%), Gaps = 11/152 (7%)
Query: 447 SLCMSWLVDHVYAIREAATLNLKKLVEQYGPQWAEN----NVIPKVLNMSHEQNYLHRMT 502
SL + L+D V I++ A L L +L Y AE +++P+++ EQN ++
Sbjct: 44 SLLRTLLLDVVPTIQQIAALALGRLAN-YNDDLAEAVVKCDILPQLVYSLAEQNRFYKKA 102
Query: 503 YLFCINVL---SEVCGKDITTRVLLPTVLSMADDNVANVRFNVAKTLQIMAKY---LDPA 556
F + + S + I L T++ +D V+ A L+ +A++ L A
Sbjct: 103 AAFVLRAVGKHSPQLAQAIVDCGALDTLVICLEDFDPGVKEAAAWALRYIARHNAELSQA 162
Query: 557 VIQPQVKPVLEKLNVDPDVDVKYFASEAIAGI 588
V+ P+L +P++ +K A+ A++ I
Sbjct: 163 VVDAGAVPLLVLCIQEPEIALKGIAASALSDI 194
>BC100980-1|AAI00981.1| 415|Homo sapiens PPP4R1L protein protein.
Length = 415
Score = 34.3 bits (75), Expect = 1.2
Identities = 32/173 (18%), Positives = 71/173 (41%), Gaps = 8/173 (4%)
Query: 405 SLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYA-IREA 463
+++ +V L+ED + VR ++E +P +A L + + +L+ V + +
Sbjct: 85 TVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQEN--RSNFPVVLSEYLIPIVVRYLTDP 142
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVC---GKDITT 520
+ K+ E ++P+ + ++ C ++C G++ T
Sbjct: 143 NNQIICKMASMLSKSTVERLLLPRFCELCGDRKLFQ--VRKVCAANFGDICHAVGQEATE 200
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDP 573
+ L+P + D V +R A+ ++ P V + Q+ P+ +L DP
Sbjct: 201 KFLIPKFFELCSDAVWGMRKACAECFTAVSHSSSPGVRRTQLFPLFIRLVSDP 253
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 12/145 (8%)
Query: 287 QIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH--IIMTMILPQIKDLVCDANQHVK 344
+I L +D+E VR ++ + L + ++ ++P + + D N +
Sbjct: 88 EIVVRLSEDAEPTVRTELMEQIPPIAIFLQENRSNFPVVLSEYLIPIVVRYLTDPNNQII 147
Query: 345 SALASVIMGLSPIVGRQNTIEHLL-PLFLTQLKD-ECPEVRLNIISNLECVNEVIGIQQL 402
+AS++ ++T+E LL P F D + +VR +N + +G +
Sbjct: 148 CKMASMLS--------KSTVERLLLPRFCELCGDRKLFQVRKVCAANFGDICHAVGQEAT 199
Query: 403 VQSLLPAIVELAEDTKWRVRLAIIE 427
+ L+P EL D W +R A E
Sbjct: 200 EKFLIPKFFELCSDAVWGMRKACAE 224
>BC100979-1|AAI00980.1| 415|Homo sapiens PPP4R1L protein protein.
Length = 415
Score = 34.3 bits (75), Expect = 1.2
Identities = 32/173 (18%), Positives = 71/173 (41%), Gaps = 8/173 (4%)
Query: 405 SLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYA-IREA 463
+++ +V L+ED + VR ++E +P +A L + + +L+ V + +
Sbjct: 85 TVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQEN--RSNFPVVLSEYLIPIVVRYLTDP 142
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVC---GKDITT 520
+ K+ E ++P+ + ++ C ++C G++ T
Sbjct: 143 NNQIICKMASMLSKSTVERLLLPRFCELCGDRKLFQ--VRKVCAANFGDICHAVGQEATE 200
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDP 573
+ L+P + D V +R A+ ++ P V + Q+ P+ +L DP
Sbjct: 201 KFLIPKFFELCSDAVWGMRKACAECFTAVSHSSSPGVRRTQLFPLFIRLVSDP 253
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 12/145 (8%)
Query: 287 QIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH--IIMTMILPQIKDLVCDANQHVK 344
+I L +D+E VR ++ + L + ++ ++P + + D N +
Sbjct: 88 EIVVRLSEDAEPTVRTELMEQIPPIAIFLQENRSNFPVVLSEYLIPIVVRYLTDPNNQII 147
Query: 345 SALASVIMGLSPIVGRQNTIEHLL-PLFLTQLKD-ECPEVRLNIISNLECVNEVIGIQQL 402
+AS++ ++T+E LL P F D + +VR +N + +G +
Sbjct: 148 CKMASMLS--------KSTVERLLLPRFCELCGDRKLFQVRKVCAANFGDICHAVGQEAT 199
Query: 403 VQSLLPAIVELAEDTKWRVRLAIIE 427
+ L+P EL D W +R A E
Sbjct: 200 EKFLIPKFFELCSDAVWGMRKACAE 224
>AL354834-1|CAI94892.2| 386|Homo sapiens protein phosphatase 4,
regulatory subunit 1-like protein.
Length = 386
Score = 34.3 bits (75), Expect = 1.2
Identities = 32/173 (18%), Positives = 71/173 (41%), Gaps = 8/173 (4%)
Query: 405 SLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYA-IREA 463
+++ +V L+ED + VR ++E +P +A L + + +L+ V + +
Sbjct: 56 TVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQEN--RSNFPVVLSEYLIPIVVRYLTDP 113
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVC---GKDITT 520
+ K+ E ++P+ + ++ C ++C G++ T
Sbjct: 114 NNQIICKMASMLSKSTVERLLLPRFCELCGDRKLFQ--VRKVCAANFGDICHAVGQEATE 171
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDP 573
+ L+P + D V +R A+ ++ P V + Q+ P+ +L DP
Sbjct: 172 KFLIPKFFELCSDAVWGMRKACAECFTAVSHSSSPGVRRTQLFPLFIRLVSDP 224
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 12/145 (8%)
Query: 287 QIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH--IIMTMILPQIKDLVCDANQHVK 344
+I L +D+E VR ++ + L + ++ ++P + + D N +
Sbjct: 59 EIVVRLSEDAEPTVRTELMEQIPPIAIFLQENRSNFPVVLSEYLIPIVVRYLTDPNNQII 118
Query: 345 SALASVIMGLSPIVGRQNTIEHLL-PLFLTQLKD-ECPEVRLNIISNLECVNEVIGIQQL 402
+AS++ ++T+E LL P F D + +VR +N + +G +
Sbjct: 119 CKMASMLS--------KSTVERLLLPRFCELCGDRKLFQVRKVCAANFGDICHAVGQEAT 170
Query: 403 VQSLLPAIVELAEDTKWRVRLAIIE 427
+ L+P EL D W +R A E
Sbjct: 171 EKFLIPKFFELCSDAVWGMRKACAE 195
>AL354776-1|CAI94993.2| 386|Homo sapiens protein phosphatase 4,
regulatory subunit 1-like protein.
Length = 386
Score = 34.3 bits (75), Expect = 1.2
Identities = 32/173 (18%), Positives = 71/173 (41%), Gaps = 8/173 (4%)
Query: 405 SLLPAIVELAEDTKWRVRLAIIEHMPLLAGQLGQEFFDEKLTSLCMSWLVDHVYA-IREA 463
+++ +V L+ED + VR ++E +P +A L + + +L+ V + +
Sbjct: 56 TVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQEN--RSNFPVVLSEYLIPIVVRYLTDP 113
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVC---GKDITT 520
+ K+ E ++P+ + ++ C ++C G++ T
Sbjct: 114 NNQIICKMASMLSKSTVERLLLPRFCELCGDRKLFQ--VRKVCAANFGDICHAVGQEATE 171
Query: 521 RVLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNVDP 573
+ L+P + D V +R A+ ++ P V + Q+ P+ +L DP
Sbjct: 172 KFLIPKFFELCSDAVWGMRKACAECFTAVSHSSSPGVRRTQLFPLFIRLVSDP 224
Score = 33.1 bits (72), Expect = 2.8
Identities = 32/145 (22%), Positives = 61/145 (42%), Gaps = 12/145 (8%)
Query: 287 QIFQALLKDSEAEVRAAAAGKVKDFCMNLDKAHQEH--IIMTMILPQIKDLVCDANQHVK 344
+I L +D+E VR ++ + L + ++ ++P + + D N +
Sbjct: 59 EIVVRLSEDAEPTVRTELMEQIPPIAIFLQENRSNFPVVLSEYLIPIVVRYLTDPNNQII 118
Query: 345 SALASVIMGLSPIVGRQNTIEHLL-PLFLTQLKD-ECPEVRLNIISNLECVNEVIGIQQL 402
+AS++ ++T+E LL P F D + +VR +N + +G +
Sbjct: 119 CKMASMLS--------KSTVERLLLPRFCELCGDRKLFQVRKVCAANFGDICHAVGQEAT 170
Query: 403 VQSLLPAIVELAEDTKWRVRLAIIE 427
+ L+P EL D W +R A E
Sbjct: 171 EKFLIPKFFELCSDAVWGMRKACAE 195
>BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein.
Length = 571
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 317 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 376
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 377 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 426
>BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AL355355-6|CAI16549.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AL355355-5|CAI16550.1| 571|Homo sapiens optineurin protein.
Length = 571
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 317 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 376
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 377 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 426
>AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3
protein.
Length = 577
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2
protein.
Length = 577
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1
protein.
Length = 577
Score = 33.1 bits (72), Expect = 2.8
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 32.3 bits (70), Expect = 4.9
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYPNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>AF061034-2|AAC16047.1| 520|Homo sapiens FIP2 protein.
Length = 520
Score = 32.3 bits (70), Expect = 4.9
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 266 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYPNKKLELQVESMLSEIKMEQAKTEDE 325
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 326 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 375
>AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 32.3 bits (70), Expect = 4.9
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Query: 464 ATLNLKKLVEQYGPQWAENNVIPKVLNMSHEQNYLHRMTYLFCINVLSEVCGKDITT--R 521
A L K+L E+ +N+ IP LN E Y ++ L ++LSE+ + T
Sbjct: 323 AELMKKRLQEKCQALERKNSAIPSELNEKQELVYPNKKLELQVESMLSEIKMEQAKTEDE 382
Query: 522 VLLPTVLSMADDNVANVRFNVAKTLQIMAKYLDPAVIQPQVKPVLEKLNV 571
TVL M + + N KT++ + + V + +K + EKL +
Sbjct: 383 KSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLEL 432
>BC031688-1|AAH31688.1| 490|Homo sapiens TEKT3 protein protein.
Length = 490
Score = 31.5 bits (68), Expect = 8.6
Identities = 27/116 (23%), Positives = 55/116 (47%), Gaps = 6/116 (5%)
Query: 271 ELQQAVGQELARTDLAQIFQALLKDSEAEVRAAAAGKV-KDFCMNLDKAHQEHIIMTMIL 329
EL + +G+ A TD+ + + L ++EA ++ A ++ M +D H E + +L
Sbjct: 163 ELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDE--VEAQLL 220
Query: 330 PQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIEHLLPLFLT--QLKDECPEVR 383
++ ++C + +K L I L+ Q+ +E L T ++ D+C +R
Sbjct: 221 TEVDTILC-CQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRINDKCHHLR 275
>BC014662-1|AAH14662.1| 688|Homo sapiens SCY1-like 3 (S.
cerevisiae) protein.
Length = 688
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AY144493-1|AAN41656.1| 742|Homo sapiens ezrin-binding protein
PACE-1 protein.
Length = 742
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AL117233-1|CAB55300.1| 688|Homo sapiens hypothetical protein
protein.
Length = 688
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AL031297-3|CAI23518.1| 742|Homo sapiens ezrin-binding partner
PACE-1 (PACE-1) protein.
Length = 742
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AL031297-2|CAB52564.2| 688|Homo sapiens ezrin-binding partner
PACE-1 (PACE-1) protein.
Length = 688
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AL031297-1|CAI23517.1| 588|Homo sapiens ezrin-binding partner
PACE-1 (PACE-1) protein.
Length = 588
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AF540957-1|AAN23123.1| 688|Homo sapiens ezrin-binding partner
PACE-1 protein.
Length = 688
Score = 31.5 bits (68), Expect = 8.6
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 354 LSPIVGRQNTIEHLLPLFLTQLKDECPEVRLNIISNLECVNEVIGIQQLVQSLLPAIVEL 413
LSP + + I LL LF ++ +E VR+ ++S++E E +QL + +LP ++
Sbjct: 329 LSPALFQSRVIPVLLQLF--EVHEE--HVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLG 384
Query: 414 AEDTKWRVRLAIIEHMPLLAGQLGQE 439
DT + + + +L LG E
Sbjct: 385 LRDTSDSIVAITLHSLAVLVSLLGPE 410
>AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein.
Length = 8749
Score = 31.5 bits (68), Expect = 8.6
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 265 VADKFVELQQAVG-QELARTDLAQIFQALLKDSEAEVRA-AAAGKVKDFCMNLDKAHQEH 322
+ D+ + +G ++ L+QI LL E EV+ A GK + + +K Q
Sbjct: 2650 IQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQR- 2708
Query: 323 IIMTMI--LPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIE 365
+I T + L ++ + ++ H +S L SVI + V R+N +E
Sbjct: 2709 VIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLE 2753
>AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein.
Length = 8797
Score = 31.5 bits (68), Expect = 8.6
Identities = 28/105 (26%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 265 VADKFVELQQAVG-QELARTDLAQIFQALLKDSEAEVRA-AAAGKVKDFCMNLDKAHQEH 322
+ D+ + +G ++ L+QI LL E EV+ A GK + + +K Q
Sbjct: 2643 IQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQR- 2701
Query: 323 IIMTMI--LPQIKDLVCDANQHVKSALASVIMGLSPIVGRQNTIE 365
+I T + L ++ + ++ H +S L SVI + V R+N +E
Sbjct: 2702 VIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLE 2746
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,291,450
Number of Sequences: 224733
Number of extensions: 2844737
Number of successful extensions: 6074
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 5624
Number of HSP's gapped (non-prelim): 200
length of query: 590
length of database: 73,234,838
effective HSP length: 94
effective length of query: 496
effective length of database: 52,109,936
effective search space: 25846528256
effective search space used: 25846528256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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