Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002324-TA|BGIBMGA002324-PA|IPR001734|Na+/solute
symporter
(581 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC110492-1|AAI10493.1| 610|Homo sapiens solute carrier family 5... 200 8e-51
AY081220-1|AAL88746.1| 610|Homo sapiens putative apical iodide ... 200 8e-51
AF536217-1|AAP46194.1| 610|Homo sapiens sodium solute symporter... 200 1e-50
AF536216-1|AAP46193.1| 610|Homo sapiens sodium solute symporter... 200 1e-50
AY299482-1|AAQ73572.1| 618|Homo sapiens sodium-iodide related c... 177 7e-44
U66088-1|AAB17378.1| 643|Homo sapiens sodium iodide symporter p... 172 3e-42
BC105049-1|AAI05050.1| 643|Homo sapiens solute carrier family 5... 172 3e-42
BC105047-1|AAI05048.1| 643|Homo sapiens solute carrier family 5... 172 3e-42
AC005796-2|AAC62827.1| 643|Homo sapiens sodium iodide symporter... 172 3e-42
BC015631-1|AAH15631.1| 635|Homo sapiens solute carrier family 5... 171 6e-42
BC012806-1|AAH12806.1| 635|Homo sapiens solute carrier family 5... 171 6e-42
AF116241-1|AAD37502.1| 635|Homo sapiens sodium-dependent multiv... 171 6e-42
AF081571-1|AAD37481.1| 635|Homo sapiens sodium-dependent multi-... 171 6e-42
AF069307-1|AAD31727.1| 635|Homo sapiens sodium-dependent multiv... 171 6e-42
AC013403-8|AAX93172.1| 635|Homo sapiens unknown protein. 171 6e-42
D87920-1|BAA24835.1| 643|Homo sapiens sodium iodide symporter p... 171 8e-42
BC049207-1|AAH49207.1| 396|Homo sapiens solute carrier family 5... 157 1e-37
BC041454-1|AAH41454.1| 392|Homo sapiens SLC5A12 protein protein. 127 1e-28
L38500-1|AAC41747.2| 718|Homo sapiens Na+/myo-inositol cotransp... 75 9e-13
AF027153-1|AAC39548.1| 718|Homo sapiens sodium/myo-inositol cot... 73 3e-12
AK125267-1|BAC86105.1| 742|Homo sapiens protein ( Homo sapiens ... 70 3e-11
AF292385-1|AAK97053.1| 675|Homo sapiens putative sodium-coupled... 70 3e-11
AY044906-1|AAK97784.1| 675|Homo sapiens sodium/glucose cotransp... 68 8e-11
AJ305237-1|CAC83728.1| 675|Homo sapiens sodium-dependent glucos... 68 8e-11
U41898-1|AAB61733.1| 178|Homo sapiens RKST1 protein. 67 2e-10
BC057780-1|AAH57780.1| 611|Homo sapiens SLC5A11 protein protein. 66 2e-10
BC049385-1|AAH49385.1| 519|Homo sapiens SLC5A11 protein protein. 66 3e-10
BC034380-1|AAH34380.1| 591|Homo sapiens SLC5A10 protein protein. 65 7e-10
M95549-1|AAA36608.1| 672|Homo sapiens sodium/glucose cotranspor... 63 3e-09
BC131542-1|AAI31543.1| 458|Homo sapiens SLC5A2 protein protein. 63 3e-09
AF307340-1|AAL66409.1| 698|Homo sapiens sodium/glucose cotransp... 63 3e-09
Z83849-1|CAI23589.1| 664|Homo sapiens solute carrier family 5 (... 62 7e-09
Z83839-4|CAB06087.1| 664|Homo sapiens solute carrier family 5 (... 62 7e-09
Z80998-1|CAI18759.1| 664|Homo sapiens solute carrier family 5 (... 62 7e-09
Z74021-2|CAI18756.1| 664|Homo sapiens solute carrier family 5 (... 62 7e-09
M24847-1|AAA60320.1| 664|Homo sapiens SGLT1 protein. 62 7e-09
L29339-1|AAB59448.1| 664|Homo sapiens Na+/glucose cotransporter... 62 7e-09
CR456579-1|CAG30465.1| 664|Homo sapiens SLC5A1 protein. 62 7e-09
BC139839-1|AAI39840.2| 669|Homo sapiens SLC5A1 protein protein. 62 7e-09
AL022321-1|CAI19810.1| 664|Homo sapiens solute carrier family 5... 62 7e-09
AL008723-4|CAB51758.1| 659|Homo sapiens solute carrier family 5... 62 7e-09
AJ133127-1|CAB81772.1| 659|Homo sapiens sodium-glucose cotransp... 62 7e-09
BC104863-1|AAI04864.1| 681|Homo sapiens SLC5A9 protein protein. 61 9e-09
BC104857-1|AAI04858.1| 681|Homo sapiens SLC5A9 protein protein. 61 9e-09
U41897-1|AAB61732.1| 175|Homo sapiens low affinity sodium gluco... 58 9e-08
AL109659-1|CAI18915.1| 699|Homo sapiens solute carrier family 5... 56 3e-07
BC062617-1|AAH62617.1| 567|Homo sapiens SLC5A10 protein protein. 40 0.032
BC039868-1|AAH39868.1| 566|Homo sapiens SLC5A10 protein protein. 36 0.30
AK057946-1|BAB71619.1| 517|Homo sapiens protein ( Homo sapiens ... 35 0.91
AK075078-1|BAC11387.1| 257|Homo sapiens protein ( Homo sapiens ... 33 2.1
CR456580-1|CAG30466.1| 635|Homo sapiens SLC7A4 protein. 32 4.9
BC107161-1|AAI07162.1| 635|Homo sapiens solute carrier family 7... 32 4.9
BC107160-1|AAI07161.1| 635|Homo sapiens solute carrier family 7... 32 4.9
BC062565-1|AAH62565.1| 635|Homo sapiens solute carrier family 7... 32 4.9
BC008814-1|AAH08814.1| 635|Homo sapiens solute carrier family 7... 32 4.9
AJ000730-1|CAA04263.1| 636|Homo sapiens cationic amino acid tra... 32 4.9
>BC110492-1|AAI10493.1| 610|Homo sapiens solute carrier family 5
(iodide transporter), member 8 protein.
Length = 610
Score = 200 bits (489), Expect = 8e-51
Identities = 128/458 (27%), Positives = 204/458 (44%), Gaps = 11/458 (2%)
Query: 5 WLAWECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTL 63
++ W+ +VFA M V S A + ++ G ++ + + LS+ +
Sbjct: 10 FVVWDYVVFAGMLVIS---AAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66
Query: 64 GVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIV--CWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE VYR A++ ++F F +V +F+PV+Y+L S YEYLE+RF
Sbjct: 67 SAVTVLGTPSE-VYRFGAIF-SIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN 124
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR F+++ +L + +Y P +AL+ V W + A VV + LGGL
Sbjct: 125 KC-VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLK 183
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A I DV Q M+ + I+QA V GG +T+ N +GGRL F+ F +P R
Sbjct: 184 AVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFW 243
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ IIG F SIYG Q+ VQRY S S + K +L N+ + + + S G+ALY+
Sbjct: 244 TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYS 303
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDP K+SAPD+++P+ V D
Sbjct: 304 RYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAV 363
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSLCVGMAGGVVEGSLLVTSATS 421
ED + P F+ +S++ + ++ + G +++ +L V
Sbjct: 364 TVEDLIK--PYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVG 421
Query: 422 XXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
P AN GA+ G++A I+ W+ +G
Sbjct: 422 GPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIG 459
>AY081220-1|AAL88746.1| 610|Homo sapiens putative apical iodide
transporter protein.
Length = 610
Score = 200 bits (489), Expect = 8e-51
Identities = 128/458 (27%), Positives = 204/458 (44%), Gaps = 11/458 (2%)
Query: 5 WLAWECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTL 63
++ W+ +VFA M V S A + ++ G ++ + + LS+ +
Sbjct: 10 FVVWDYVVFAGMLVIS---AAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66
Query: 64 GVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIV--CWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE VYR A++ ++F F +V +F+PV+Y+L S YEYLE+RF
Sbjct: 67 SAVTVLGTPSE-VYRFGAIF-SIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN 124
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR F+++ +L + +Y P +AL+ V W + A VV + LGGL
Sbjct: 125 KC-VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLK 183
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A I DV Q M+ + I+QA V GG +T+ N +GGRL F+ F +P R
Sbjct: 184 AVIWTDVFQVGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFW 243
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ IIG F SIYG Q+ VQRY S S + K +L N+ + + + S G+ALY+
Sbjct: 244 TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYS 303
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDP K+SAPD+++P+ V D
Sbjct: 304 RYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAV 363
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSLCVGMAGGVVEGSLLVTSATS 421
ED + P F+ +S++ + ++ + G +++ +L V
Sbjct: 364 TVEDLIK--PYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVG 421
Query: 422 XXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
P AN GA+ G++A I+ W+ +G
Sbjct: 422 GPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIG 459
>AF536217-1|AAP46194.1| 610|Homo sapiens sodium solute symporter
family 5 member 8 protein protein.
Length = 610
Score = 200 bits (488), Expect = 1e-50
Identities = 128/458 (27%), Positives = 204/458 (44%), Gaps = 11/458 (2%)
Query: 5 WLAWECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTL 63
++ W+ +VFA M V S A + ++ G ++ + + LS+ +
Sbjct: 10 FVVWDYVVFAGMLVIS---AAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66
Query: 64 GVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIV--CWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE VYR A++ ++F F +V +F+PV+Y+L S YEYLE+RF
Sbjct: 67 SAVTVLGTPSE-VYRFGAIF-SIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN 124
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR F+++ +L + +Y P +AL+ V W + A VV + LGGL
Sbjct: 125 KC-VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLK 183
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A I DV Q M+ + I+QA V GG +T+ N +GGRL F+ F +P R
Sbjct: 184 AVIWTDVFQIGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFW 243
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ IIG F SIYG Q+ VQRY S S + K +L N+ + + + S G+ALY+
Sbjct: 244 TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYS 303
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDP K+SAPD+++P+ V D
Sbjct: 304 RYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAV 363
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSLCVGMAGGVVEGSLLVTSATS 421
ED + P F+ +S++ + ++ + G +++ +L V
Sbjct: 364 TVEDLIK--PYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVG 421
Query: 422 XXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
P AN GA+ G++A I+ W+ +G
Sbjct: 422 GPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIG 459
>AF536216-1|AAP46193.1| 610|Homo sapiens sodium solute symporter
family 5 member 8 protein protein.
Length = 610
Score = 200 bits (488), Expect = 1e-50
Identities = 128/458 (27%), Positives = 204/458 (44%), Gaps = 11/458 (2%)
Query: 5 WLAWECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTL 63
++ W+ +VFA M V S A + ++ G ++ + + LS+ +
Sbjct: 10 FVVWDYVVFAGMLVIS---AAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFM 66
Query: 64 GVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIV--CWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE VYR A++ ++F F +V +F+PV+Y+L S YEYLE+RF
Sbjct: 67 SAVTVLGTPSE-VYRFGAIF-SIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN 124
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR F+++ +L + +Y P +AL+ V W + A VV + LGGL
Sbjct: 125 KC-VRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLK 183
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A I DV Q M+ + I+QA V GG +T+ N +GGRL F+ F +P R
Sbjct: 184 AVIWTDVFQIGIMVAGFASVIIQAVVMQGGISTILNDAYDGGRLNFWNFNPNPLQRHTFW 243
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ IIG F SIYG Q+ VQRY S S + K +L N+ + + + S G+ALY+
Sbjct: 244 TIIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAKLSLYINLVGLWAILTCSVFCGLALYS 303
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDP K+SAPD+++P+ V D
Sbjct: 304 RYHDCDPWTAKKVSAPDQLMPYLVLDILQDYPGLPGLFVACAYSGTLSTVSSSINALAAV 363
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSLCVGMAGGVVEGSLLVTSATS 421
ED + P F+ +S++ + ++ + G +++ +L V
Sbjct: 364 TVEDLIK--PYFRSLSERSLSWISQGMSVVYGALCIGMAALASLMGALLQAALSVFGMVG 421
Query: 422 XXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
P AN GA+ G++A I+ W+ +G
Sbjct: 422 GPLMGLFALGILVPFANSIGALVGLMAGFAISLWVGIG 459
>AY299482-1|AAQ73572.1| 618|Homo sapiens sodium-iodide related
cotransporter protein.
Length = 618
Score = 177 bits (432), Expect = 7e-44
Identities = 123/456 (26%), Positives = 195/456 (42%), Gaps = 13/456 (2%)
Query: 8 WECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTLGVR 66
W+ +VFA +F S+ + ++ G +S + LS+ +
Sbjct: 9 WDYVVFAALFFISSGIGVFFAIKERKKATSRE---FLVGGRQMSFGPVGLSLTASFMSAV 65
Query: 67 SFLGFPSEQVYRGSAMWETLF-GMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFGSIWV 125
+ LG PSE VYR A + F + + +F+PV+YR S YEYL++RF V
Sbjct: 66 TVLGTPSE-VYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP-V 123
Query: 126 RRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLAAAIR 185
R A ++++ +L V VY P +AL+ V W S A +V + LGGL A +
Sbjct: 124 RYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVW 183
Query: 186 ADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTLSAII 245
D Q + MI+ ++Q + AGG V + G RL F F DP R + +
Sbjct: 184 TDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITV 243
Query: 246 GQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYAVYKY 305
G F + IYG Q+ +QR S +E K L N+ + V+ + G+ +Y+ +K
Sbjct: 244 GGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWVILVCAVFSGLIMYSHFKD 303
Query: 306 CDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWED 365
CDP + ISAPD+++P++V + +ED
Sbjct: 304 CDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFED 363
Query: 366 FVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSLCV--GMAGGVVEGSLLVTSATSXX 423
FV + F +SDK L+ MC S+ V + GGVV+ SL +
Sbjct: 364 FVKSC--FPHLSDK--LSTWISKGLCLLFGVMCTSMSVAASVMGGVVQASLSIHGMCGGP 419
Query: 424 XXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
P N GA+ G++ ++ W+A+G
Sbjct: 420 MLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIG 455
>U66088-1|AAB17378.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 172 bits (418), Expect = 3e-42
Identities = 111/459 (24%), Positives = 189/459 (41%), Gaps = 6/459 (1%)
Query: 2 KPGWLAWECIVFAMFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARG 61
+P + AW+ VFA+ + ++ LW + G ++ L + LS++
Sbjct: 9 RPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAED--FFTGGRRLAALPVGLSLSAS 66
Query: 62 TLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE G G +L + +F+PV+YRL S YEYLEMRF
Sbjct: 67 FMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS 126
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR +++ +L + +Y P + L+ V L WAS + ++ + +GG+
Sbjct: 127 RA-VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMK 185
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A + DV Q + M+ + + + GGP V R+ F DP R
Sbjct: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFW 245
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ ++G + +S+YG Q VQRY + +E + K LL N + ++ S + G+ ++
Sbjct: 246 TFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFV 305
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDPL +ISAPD+ +P V D
Sbjct: 306 FYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV 365
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCL-SLCVGMAGGVVEGSLLVTSAT 420
ED + P + ++ ++ + + + +L + GGV++GS V
Sbjct: 366 TVEDLIK--PRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI 423
Query: 421 SXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
S PA N G + G+ A ++ W+A+G
Sbjct: 424 SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALG 462
>BC105049-1|AAI05050.1| 643|Homo sapiens solute carrier family 5
(sodium iodide symporter), member 5 protein.
Length = 643
Score = 172 bits (418), Expect = 3e-42
Identities = 111/459 (24%), Positives = 189/459 (41%), Gaps = 6/459 (1%)
Query: 2 KPGWLAWECIVFAMFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARG 61
+P + AW+ VFA+ + ++ LW + G ++ L + LS++
Sbjct: 9 RPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAED--FFTGGRRLAALPVGLSLSAS 66
Query: 62 TLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE G G +L + +F+PV+YRL S YEYLEMRF
Sbjct: 67 FMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS 126
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR +++ +L + +Y P + L+ V L WAS + ++ + +GG+
Sbjct: 127 RA-VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMK 185
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A + DV Q + M+ + + + GGP V R+ F DP R
Sbjct: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFW 245
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ ++G + +S+YG Q VQRY + +E + K LL N + ++ S + G+ ++
Sbjct: 246 TFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFV 305
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDPL +ISAPD+ +P V D
Sbjct: 306 FYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV 365
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCL-SLCVGMAGGVVEGSLLVTSAT 420
ED + P + ++ ++ + + + +L + GGV++GS V
Sbjct: 366 TVEDLIK--PRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI 423
Query: 421 SXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
S PA N G + G+ A ++ W+A+G
Sbjct: 424 SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALG 462
>BC105047-1|AAI05048.1| 643|Homo sapiens solute carrier family 5
(sodium iodide symporter), member 5 protein.
Length = 643
Score = 172 bits (418), Expect = 3e-42
Identities = 111/459 (24%), Positives = 189/459 (41%), Gaps = 6/459 (1%)
Query: 2 KPGWLAWECIVFAMFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARG 61
+P + AW+ VFA+ + ++ LW + G ++ L + LS++
Sbjct: 9 RPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAED--FFTGGRRLAALPVGLSLSAS 66
Query: 62 TLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE G G +L + +F+PV+YRL S YEYLEMRF
Sbjct: 67 FMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS 126
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR +++ +L + +Y P + L+ V L WAS + ++ + +GG+
Sbjct: 127 RA-VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMK 185
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A + DV Q + M+ + + + GGP V R+ F DP R
Sbjct: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFW 245
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ ++G + +S+YG Q VQRY + +E + K LL N + ++ S + G+ ++
Sbjct: 246 TFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFV 305
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDPL +ISAPD+ +P V D
Sbjct: 306 FYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV 365
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCL-SLCVGMAGGVVEGSLLVTSAT 420
ED + P + ++ ++ + + + +L + GGV++GS V
Sbjct: 366 TVEDLIK--PRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI 423
Query: 421 SXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
S PA N G + G+ A ++ W+A+G
Sbjct: 424 SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALG 462
>AC005796-2|AAC62827.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 172 bits (418), Expect = 3e-42
Identities = 111/459 (24%), Positives = 189/459 (41%), Gaps = 6/459 (1%)
Query: 2 KPGWLAWECIVFAMFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARG 61
+P + AW+ VFA+ + ++ LW + G ++ L + LS++
Sbjct: 9 RPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAED--FFTGGRRLAALPVGLSLSAS 66
Query: 62 TLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE G G +L + +F+PV+YRL S YEYLEMRF
Sbjct: 67 FMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS 126
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR +++ +L + +Y P + L+ V L WAS + ++ + +GG+
Sbjct: 127 RA-VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMK 185
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A + DV Q + M+ + + + GGP V R+ F DP R
Sbjct: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFW 245
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ ++G + +S+YG Q VQRY + +E + K LL N + ++ S + G+ ++
Sbjct: 246 TFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFV 305
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDPL +ISAPD+ +P V D
Sbjct: 306 FYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV 365
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCL-SLCVGMAGGVVEGSLLVTSAT 420
ED + P + ++ ++ + + + +L + GGV++GS V
Sbjct: 366 TVEDLIK--PRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI 423
Query: 421 SXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
S PA N G + G+ A ++ W+A+G
Sbjct: 424 SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALG 462
>BC015631-1|AAH15631.1| 635|Homo sapiens solute carrier family 5
(sodium-dependent vitamin transporter), member 6
protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>BC012806-1|AAH12806.1| 635|Homo sapiens solute carrier family 5
(sodium-dependent vitamin transporter), member 6
protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>AF116241-1|AAD37502.1| 635|Homo sapiens sodium-dependent
multivitamin transporter protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>AF081571-1|AAD37481.1| 635|Homo sapiens sodium-dependent
multi-vitamin transporter protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>AF069307-1|AAD31727.1| 635|Homo sapiens sodium-dependent
multivitamin transporter protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>AC013403-8|AAX93172.1| 635|Homo sapiens unknown protein.
Length = 635
Score = 171 bits (416), Expect = 6e-42
Identities = 116/423 (27%), Positives = 179/423 (42%), Gaps = 5/423 (1%)
Query: 43 IFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYR-GSAMWETLFGMVLAFPIVCWIFV 101
+ A + L + LS+ + LG PSE +YR G+ W L I IF+
Sbjct: 60 LMADRKMGCLPVALSLLATFQSAVAILGVPSE-IYRFGTQYWFLGCCYFLGLLIPAHIFI 118
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHW 161
PV+YRL S YEYLE+RF VR TF+ + V+ + V +Y P++AL+AV W
Sbjct: 119 PVFYRLHLTSAYEYLELRFNKT-VRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLW 177
Query: 162 ASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLE 221
S AL +V V+ LGGL A I DV QTL M L A I+ + K GG V+ +
Sbjct: 178 LSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQ 237
Query: 222 GGRLKFFQFTWDPTVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLAN 281
GR+ F+ DP VR + G +FM +S+YG Q VQRY S +E + A
Sbjct: 238 HGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLSSRTEKAAVLSCYAV 297
Query: 282 VPAVSVLFSLSWIVGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXX 341
P V + ++G+ ++A Y+ +APD+ + ++V D
Sbjct: 298 FPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGLPGLPGLFIA 357
Query: 342 XXXXXXXXXXXXXXXXXXXXXWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCLSL 401
ED + P F S+ + + + ++
Sbjct: 358 CLFSGSLSTISSAFNSLATVTMEDLI--RPWFPEFSEARAIMLSRGLAFGYGLLCLGMAY 415
Query: 402 CVGMAGGVVEGSLLVTSATSXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVGRL 461
G V++ ++ + P AN GAV G++A ++ W+ +G +
Sbjct: 416 ISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSI 475
Query: 462 FMS 464
S
Sbjct: 476 VTS 478
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 517 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 574
>D87920-1|BAA24835.1| 643|Homo sapiens sodium iodide symporter
protein.
Length = 643
Score = 171 bits (415), Expect = 8e-42
Identities = 111/459 (24%), Positives = 189/459 (41%), Gaps = 6/459 (1%)
Query: 2 KPGWLAWECIVFAMFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARG 61
+P + AW+ VFA+ + ++ LW + G ++ L + LS++
Sbjct: 9 RPTFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAED--FFTGGRRLAALPVGLSLSAS 66
Query: 62 TLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFG 121
+ LG PSE G G +L + +F+PV+YRL S YEYLEMRF
Sbjct: 67 FMSAVQVLGVPSEAYRYGLKFLWMCLGQLLNSVLTPLLFMPVFYRLGLTSTYEYLEMRFS 126
Query: 122 SIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLA 181
VR +++ +L + +Y P + L+ V L WAS + ++ + +GG+
Sbjct: 127 RA-VRLCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMK 185
Query: 182 AAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTL 241
A + DV Q + M+ + + + GGP V R+ F DP R
Sbjct: 186 AVVWTDVFQVVVMLSGFWVVLARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFW 245
Query: 242 SAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYA 301
+ ++G + +S+YG Q VQRY + +E + K LL N + ++ S + G+ ++
Sbjct: 246 TFVVGGTLVWLSMYGVNQAQVQRYVACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFV 305
Query: 302 VYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 361
Y CDPL +ISAPD+ +P V D
Sbjct: 306 FYTDCDPLLLGRISAPDQYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAV 365
Query: 362 XWEDFVSAAPSFKGISDKQQLTXXXXXXXXXXXXXMCL-SLCVGMAGGVVEGSLLVTSAT 420
ED + P + ++ ++ + + + +L + GGV++GS V
Sbjct: 366 TVEDLIK--PRLRSLAPRKLVIISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVI 423
Query: 421 SXXXXXXXXXXXXCPAANGTGAVWGMIASHIITTWMAVG 459
S PA N G + G+ A ++ W+A+G
Sbjct: 424 SGPLLGAFILGMFLPACNTPGVLAGLGAGLALSLWVALG 462
>BC049207-1|AAH49207.1| 396|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 12 protein.
Length = 396
Score = 157 bits (381), Expect = 1e-37
Identities = 103/374 (27%), Positives = 164/374 (43%), Gaps = 9/374 (2%)
Query: 8 WECIVFA-MFVCSTSCAPLWXXXXXXXXXXXXXXXYIFAGTGVSTLAMILSVARGTLGVR 66
W+ +VFA +F S+ + ++ G +S + LS+ +
Sbjct: 9 WDYVVFAALFFISSGIGVFFAIKERKKATSRE---FLVGGRQMSFGPVGLSLTASFMSAV 65
Query: 67 SFLGFPSEQVYRGSAMWETLF-GMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFGSIWV 125
+ LG PSE VYR A + F + + +F+PV+YR S YEYL++RF V
Sbjct: 66 TVLGTPSE-VYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKP-V 123
Query: 126 RRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNLLGGLAAAIR 185
R A ++++ +L V VY P +AL+ V W S A +V + LGGL A +
Sbjct: 124 RYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVW 183
Query: 186 ADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDPTVRVDTLSAII 245
D Q + MI+ ++Q + AGG V + G RL F F DP R + +
Sbjct: 184 TDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITV 243
Query: 246 GQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWIVGMALYAVYKY 305
G F + IYG Q+ +QR S +E K L N+ + ++ + G+ +Y+ +K
Sbjct: 244 GGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKD 303
Query: 306 CDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXWED 365
CDP + ISAPD+++P++V + +ED
Sbjct: 304 CDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFED 363
Query: 366 FVSAAPSFKGISDK 379
FV + F +SDK
Sbjct: 364 FVKSC--FPHLSDK 375
>BC041454-1|AAH41454.1| 392|Homo sapiens SLC5A12 protein protein.
Length = 392
Score = 127 bits (306), Expect = 1e-28
Identities = 75/265 (28%), Positives = 118/265 (44%), Gaps = 3/265 (1%)
Query: 115 YLEMRFGSIWVRRIAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVF 174
YL++RF VR A ++++ +L V VY P +AL+ V W S A +V +
Sbjct: 41 YLQLRFNKP-VRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFY 99
Query: 175 NLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGGPATVFNGNLEGGRLKFFQFTWDP 234
LGGL A + D Q + MI+ ++Q + AGG V + G RL F F DP
Sbjct: 100 CTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDP 159
Query: 235 TVRVDTLSAIIGQLFMSISIYGCQQTFVQRYCSMSSESRVKKTLLANVPAVSVLFSLSWI 294
R + +G F + IYG Q+ +QR S +E K L N+ + ++ +
Sbjct: 160 LRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVF 219
Query: 295 VGMALYAVYKYCDPLATSKISAPDEILPFYVQDQXXXXXXXXXXXXXXXXXXXXXXXXXX 354
G+ +Y+ +K CDP + ISAPD+++P++V +
Sbjct: 220 SGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASS 279
Query: 355 XXXXXXXXWEDFVSAAPSFKGISDK 379
+EDFV + F +SDK
Sbjct: 280 INALATVTFEDFVKSC--FPHLSDK 302
>L38500-1|AAC41747.2| 718|Homo sapiens Na+/myo-inositol
cotransporter protein.
Length = 718
Score = 74.5 bits (175), Expect = 9e-13
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG ++ +A+ S+ +G F+G G A+ F +L ++ W+F+
Sbjct: 39 YFLAGRSMTWVAIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFI 98
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y R ++ EYL RFG ++ AA + +L L+V +Y+ + + L
Sbjct: 99 PIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNL 158
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ S L ++ + + GGL A I D +Q L MI+ + ++ + ++ GG
Sbjct: 159 YVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGG 209
>AF027153-1|AAC39548.1| 718|Homo sapiens sodium/myo-inositol
cotransporter protein.
Length = 718
Score = 72.9 bits (171), Expect = 3e-12
Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG ++ + + S+ +G F+G G A+ F +L ++ W+F+
Sbjct: 39 YFLAGRSMTWVTIGASLFVSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFI 98
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y R ++ EYL RFG ++ AA + +L L+V +Y+ + + L
Sbjct: 99 PIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSLILYIFTKLSVDLYSGALFIQESLGWNL 158
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ S L ++ + + GGL A I D +Q L MI+ + ++ + ++ GG
Sbjct: 159 YVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGG 209
>AK125267-1|BAC86105.1| 742|Homo sapiens protein ( Homo sapiens
cDNA FLJ43277 fis, clone KIDNE2011635, highly similar
to Rabbit mRNA for sodium-glucose cotransporter. ).
Length = 742
Score = 69.7 bits (163), Expect = 3e-11
Identities = 43/171 (25%), Positives = 78/171 (45%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG + + S+ +G F+G G ++ + + ++ WIF+
Sbjct: 125 YFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFL 184
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPH 160
P+Y ++ EYL RFG I + I A +L + ++V +Y + + L L
Sbjct: 185 PIYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDL 244
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ + A L ++ V+ + GGLAA I D +QTL M++ + + + GG
Sbjct: 245 YLAIAGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGG 295
>AF292385-1|AAK97053.1| 675|Homo sapiens putative sodium-coupled
cotransporter RKST1 protein.
Length = 675
Score = 69.7 bits (163), Expect = 3e-11
Identities = 43/171 (25%), Positives = 78/171 (45%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG + + S+ +G F+G G ++ + + ++ WIF+
Sbjct: 58 YFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFL 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPH 160
P+Y ++ EYL RFG I + I A +L + ++V +Y + + L L
Sbjct: 118 PIYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ + A L ++ V+ + GGLAA I D +QTL M++ + + + GG
Sbjct: 178 YLAIAGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGG 228
>AY044906-1|AAK97784.1| 675|Homo sapiens sodium/glucose
cotransporter KST1 protein.
Length = 675
Score = 68.1 bits (159), Expect = 8e-11
Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG + + S+ +G F+G G ++ + + ++ WIF+
Sbjct: 58 YFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFL 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVL-NLAVTVYTPTVALHAVLALPH 160
P+Y ++ EYL RFG I + I A +L + ++V +Y + + L L
Sbjct: 118 PIYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ + L ++ V+ + GGLAA I D +QTL M++ + + + GG
Sbjct: 178 YLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGG 228
>AJ305237-1|CAC83728.1| 675|Homo sapiens sodium-dependent glucose
transporter protein.
Length = 675
Score = 68.1 bits (159), Expect = 8e-11
Identities = 42/171 (24%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG + + S+ +G F+G G ++ + + ++ WIF+
Sbjct: 58 YFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFL 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVL-NLAVTVYTPTVALHAVLALPH 160
P+Y ++ EYL RFG I + I A +L + ++V +Y + + L L
Sbjct: 118 PIYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ + L ++ V+ + GGLAA I D +QTL M++ + + + GG
Sbjct: 178 YLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGG 228
>U41898-1|AAB61733.1| 178|Homo sapiens RKST1 protein.
Length = 178
Score = 66.9 bits (156), Expect = 2e-10
Identities = 38/156 (24%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 57 SVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYL 116
S+ +G F+G G ++ + + ++ W+F+P+Y ++ EYL
Sbjct: 1 SLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWVFLPIYIAGQVTTMPEYL 60
Query: 117 EMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPHWASAAALTVVSIVFN 175
RFG I + I A +L + ++V +Y + + L L + + L ++ V+
Sbjct: 61 RKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYT 120
Query: 176 LLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ GGLAA I D +QTL M++ + + + GG
Sbjct: 121 VAGGLAAVIYTDALQTLIMLIGALTLMCYSFAAVGG 156
>BC057780-1|AAH57780.1| 611|Homo sapiens SLC5A11 protein protein.
Length = 611
Score = 66.5 bits (155), Expect = 2e-10
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 1/156 (0%)
Query: 57 SVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYL 116
S+ +G F+G G ++ + + ++ WIF+P+Y ++ EYL
Sbjct: 9 SLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYL 68
Query: 117 EMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPHWASAAALTVVSIVFN 175
RFG I + I A +L + ++V +Y + + L L + + L ++ V+
Sbjct: 69 RKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYT 128
Query: 176 LLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ GGLAA I D +QTL M++ + + + GG
Sbjct: 129 VAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGG 164
>BC049385-1|AAH49385.1| 519|Homo sapiens SLC5A11 protein protein.
Length = 519
Score = 66.1 bits (154), Expect = 3e-10
Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 1/141 (0%)
Query: 57 SVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYL 116
S+ +G F+G G ++ + + ++ WIF+P+Y ++ EYL
Sbjct: 9 SLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYL 68
Query: 117 EMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPHWASAAALTVVSIVFN 175
RFG I + I A +L + ++V +Y + + L L + + L ++ V+
Sbjct: 69 RKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYT 128
Query: 176 LLGGLAAAIRADVIQTLTMIL 196
+ GGLAA I D +QTL M++
Sbjct: 129 VAGGLAAVIYTDALQTLIMLI 149
>BC034380-1|AAH34380.1| 591|Homo sapiens SLC5A10 protein protein.
Length = 591
Score = 64.9 bits (151), Expect = 7e-10
Identities = 40/171 (23%), Positives = 77/171 (45%), Gaps = 1/171 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG ++ + S+ + G F+G G A+ + + W+FV
Sbjct: 45 YFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFV 104
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPH 160
P+Y ++ EY++ R+G +R + LL V +++ +Y + +H L
Sbjct: 105 PIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNF 164
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+ S ++ ++ + GGLAA I D +QTL M++ + ++A + GG
Sbjct: 165 YLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGG 215
>M95549-1|AAA36608.1| 672|Homo sapiens sodium/glucose
cotransporter-like protein protein.
Length = 672
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/202 (25%), Positives = 92/202 (45%), Gaps = 15/202 (7%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAM----WETLFGMVLAFPIVC 97
Y AG + + S+ +G F+G G A+ W LF ++L +
Sbjct: 55 YFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLL----LG 110
Query: 98 WIFVPVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVL 156
W+F PVY ++ +YL RFG +R + L + ++V +++ V + L
Sbjct: 111 WLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQAL 170
Query: 157 ALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQ--ATVKAGGPAT 214
+AS AL +++++ + GGLAA + D +Q T +++ GA I+ A + GG +
Sbjct: 171 GWNIYASVIALLGITMIYTVTGGLAALMYTDTVQ--TFVILGGACILMGYAFHEVGGYSG 228
Query: 215 VFNGNLEGGRLKFFQFTWDPTV 236
+F+ L G + DP V
Sbjct: 229 LFDKYL--GAATSLTVSEDPAV 248
>BC131542-1|AAI31543.1| 458|Homo sapiens SLC5A2 protein protein.
Length = 458
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/202 (25%), Positives = 92/202 (45%), Gaps = 15/202 (7%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAM----WETLFGMVLAFPIVC 97
Y AG + + S+ +G F+G G A+ W LF ++L +
Sbjct: 55 YFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLL----LG 110
Query: 98 WIFVPVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVL 156
W+F PVY ++ +YL RFG +R + L + ++V +++ V + L
Sbjct: 111 WLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQAL 170
Query: 157 ALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQ--ATVKAGGPAT 214
+AS AL +++++ + GGLAA + D +Q T +++ GA I+ A + GG +
Sbjct: 171 GWNIYASVIALLGITMIYTVTGGLAALMYTDTVQ--TFVILGGACILMGYAFHEVGGYSG 228
Query: 215 VFNGNLEGGRLKFFQFTWDPTV 236
+F+ L G + DP V
Sbjct: 229 LFDKYL--GAATSLTVSEDPAV 248
>AF307340-1|AAL66409.1| 698|Homo sapiens sodium/glucose
cotransporter protein.
Length = 698
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/202 (25%), Positives = 92/202 (45%), Gaps = 15/202 (7%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAM----WETLFGMVLAFPIVC 97
Y AG + + S+ +G F+G G A+ W LF ++L +
Sbjct: 55 YFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLL----LG 110
Query: 98 WIFVPVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVL 156
W+F PVY ++ +YL RFG +R + L + ++V +++ V + L
Sbjct: 111 WLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQAL 170
Query: 157 ALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQ--ATVKAGGPAT 214
+AS AL +++++ + GGLAA + D +Q T +++ GA I+ A + GG +
Sbjct: 171 GWNIYASVIALLGITMIYTVTGGLAALMYTDTVQ--TFVILGGACILMGYAFHEVGGYSG 228
Query: 215 VFNGNLEGGRLKFFQFTWDPTV 236
+F+ L G + DP V
Sbjct: 229 LFDKYL--GAATSLTVSEDPAV 248
>Z83849-1|CAI23589.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>Z83839-4|CAB06087.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>Z80998-1|CAI18759.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>Z74021-2|CAI18756.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>M24847-1|AAA60320.1| 664|Homo sapiens SGLT1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>L29339-1|AAB59448.1| 664|Homo sapiens Na+/glucose cotransporter
protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>CR456579-1|CAG30465.1| 664|Homo sapiens SLC5A1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>BC139839-1|AAI39840.2| 669|Homo sapiens SLC5A1 protein protein.
Length = 669
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>AL022321-1|CAI19810.1| 664|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 1 protein.
Length = 664
Score = 61.7 bits (143), Expect = 7e-09
Identities = 35/158 (22%), Positives = 76/158 (48%), Gaps = 1/158 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG + + S+ +G F+G G A+ + ++ ++ W+FV
Sbjct: 58 FFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIAIGGFEWNALVLVVVLGWLFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL RFG ++ ++ + LL ++ +++ + ++ L L
Sbjct: 118 PIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLSLLLYIFTKISADIFSGAIFINLALGLNL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVS 198
+ + L ++ ++ + GGLAA I D +QT+ M++ S
Sbjct: 178 YLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVGS 215
>AL008723-4|CAB51758.1| 659|Homo sapiens solute carrier family 5
(low affinity glucose cotransporter), member 4 protein.
Length = 659
Score = 61.7 bits (143), Expect = 7e-09
Identities = 39/163 (23%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG ++ M S+ +G ++G G A + + I+ WIFV
Sbjct: 58 FFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL+ RFG ++ ++ + + VL ++ ++ + + L L
Sbjct: 118 PIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
+ + L ++ V+ GGLA+ I D +QT+ M++ G+FI+
Sbjct: 178 YLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLI--GSFIL 218
>AJ133127-1|CAB81772.1| 659|Homo sapiens sodium-glucose
cotransporter protein.
Length = 659
Score = 61.7 bits (143), Expect = 7e-09
Identities = 39/163 (23%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
+ AG ++ M S+ +G ++G G A + + I+ WIFV
Sbjct: 58 FFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLILGWIFV 117
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y + ++ EYL+ RFG ++ ++ + + VL ++ ++ + + L L
Sbjct: 118 PIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIKLALGLDL 177
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
+ + L ++ V+ GGLA+ I D +QT+ M++ G+FI+
Sbjct: 178 YLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLI--GSFIL 218
>BC104863-1|AAI04864.1| 681|Homo sapiens SLC5A9 protein protein.
Length = 681
Score = 61.3 bits (142), Expect = 9e-09
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG +S + S+ +G F+G G A+ + + W+FV
Sbjct: 67 YFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFV 126
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPH 160
PVY ++ +YL+ RFG ++ + L+ + ++ +++ + + L
Sbjct: 127 PVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNL 186
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
+ S L VV+ V+ + GGL A I D +Q T+I+V GA ++
Sbjct: 187 YLSTGILLVVTAVYTIAGGLMAVIYTDALQ--TVIMVGGALVL 227
>BC104857-1|AAI04858.1| 681|Homo sapiens SLC5A9 protein protein.
Length = 681
Score = 61.3 bits (142), Expect = 9e-09
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG +S + S+ +G F+G G A+ + + W+FV
Sbjct: 67 YFLAGRSMSWWPIGASLMSSNVGSGLFIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFV 126
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVLALPH 160
PVY ++ +YL+ RFG ++ + L+ + ++ +++ + + L
Sbjct: 127 PVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNL 186
Query: 161 WASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
+ S L VV+ V+ + GGL A I D +Q T+I+V GA ++
Sbjct: 187 YLSTGILLVVTAVYTIAGGLMAVIYTDALQ--TVIMVGGALVL 227
>U41897-1|AAB61732.1| 175|Homo sapiens low affinity sodium glucose
cotransporter SAAT1 protein.
Length = 175
Score = 58.0 bits (134), Expect = 9e-08
Identities = 31/110 (28%), Positives = 61/110 (55%), Gaps = 3/110 (2%)
Query: 95 IVCWIFVPVYYRLSTNSVYEYLEMRFGSIWVR-RIAAATFLLRQVLNLAVTVYTPTVALH 153
I+ WIFVP+Y + ++ EYL+ RFG ++ ++ + + VL ++ ++ + +
Sbjct: 39 ILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLLISADIFAGAIFIK 98
Query: 154 AVLALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
L L + + L ++ V+ GGLA+ I D +QT+ M++ G+FI+
Sbjct: 99 LALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLI--GSFIL 146
>AL109659-1|CAI18915.1| 699|Homo sapiens solute carrier family 5
(sodium/glucose cotransporter), member 9 protein.
Length = 699
Score = 56.0 bits (129), Expect = 3e-07
Identities = 30/107 (28%), Positives = 56/107 (52%), Gaps = 3/107 (2%)
Query: 98 WIFVPVYYRLSTNSVYEYLEMRFGSIWVRRIAAATFLLRQVLN-LAVTVYTPTVALHAVL 156
W+FVPVY ++ +YL+ RFG ++ + L+ + ++ +++ + + L
Sbjct: 141 WVFVPVYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMAL 200
Query: 157 ALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIV 203
+ S L VV+ V+ + GGL A I D +Q T+I+V GA ++
Sbjct: 201 GWNLYLSTGILLVVTAVYTIAGGLMAVIYTDALQ--TVIMVGGALVL 245
>BC062617-1|AAH62617.1| 567|Homo sapiens SLC5A10 protein protein.
Length = 567
Score = 39.5 bits (88), Expect = 0.032
Identities = 25/136 (18%), Positives = 57/136 (41%), Gaps = 1/136 (0%)
Query: 42 YIFAGTGVSTLAMILSVARGTLGVRSFLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFV 101
Y AG ++ + S+ + G F+G G A+ + + W+FV
Sbjct: 48 YFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFV 107
Query: 102 PVYYRLSTNSVYEYLEMRFGSIWVRR-IAAATFLLRQVLNLAVTVYTPTVALHAVLALPH 160
P+Y ++ EY++ R+G +R ++ + LL +++ +Y + +H L
Sbjct: 108 PIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNF 167
Query: 161 WASAAALTVVSIVFNL 176
+ S ++ ++ +
Sbjct: 168 YLSTILTLGITALYTI 183
>BC039868-1|AAH39868.1| 566|Homo sapiens SLC5A10 protein protein.
Length = 566
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/110 (18%), Positives = 47/110 (42%), Gaps = 1/110 (0%)
Query: 68 FLGFPSEQVYRGSAMWETLFGMVLAFPIVCWIFVPVYYRLSTNSVYEYLEMRFGSIWVRR 127
F+G G A+ + + W+FVP+Y ++ EY++ R+G +R
Sbjct: 20 FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 79
Query: 128 -IAAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL 176
++ + LL +++ +Y + +H L + S ++ ++ +
Sbjct: 80 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTI 129
>AK057946-1|BAB71619.1| 517|Homo sapiens protein ( Homo sapiens
cDNA FLJ25217 fis, clone REC08938, highly similar to
Oryctolagus cuniculus Na+/glucose cotransporter-related
protein ).
Length = 517
Score = 34.7 bits (76), Expect = 0.91
Identities = 17/60 (28%), Positives = 31/60 (51%)
Query: 152 LHAVLALPHWASAAALTVVSIVFNLLGGLAAAIRADVIQTLTMILVSGAFIVQATVKAGG 211
+H L + S ++ ++ + GGLAA I D +QTL M++ + ++A + GG
Sbjct: 66 VHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGG 125
>AK075078-1|BAC11387.1| 257|Homo sapiens protein ( Homo sapiens
cDNA FLJ90597 fis, clone PLACE1001231, highly similar to
Sodium-dependent multivitamin transporter. ).
Length = 257
Score = 33.5 bits (73), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 464 SNLHKMYSISYMWYAXXXXXXXXXXXXXXSLLTWKETDR-YDEKLLHPLVAKLSRKLP 520
+ L + YS+SY+WY+ SLLT + R + ++P++ KL LP
Sbjct: 139 TGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLP 196
>CR456580-1|CAG30466.1| 635|Homo sapiens SLC7A4 protein.
Length = 635
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 536 REDLFQIPMVPLIPALSIV 554
>BC107161-1|AAI07162.1| 635|Homo sapiens solute carrier family 7
(cationic amino acid transporter, y+ system), member 4
protein.
Length = 635
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 536 REDLFQIPMVPLIPALSIV 554
>BC107160-1|AAI07161.1| 635|Homo sapiens solute carrier family 7
(cationic amino acid transporter, y+ system), member 4
protein.
Length = 635
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 536 REDLFQIPMVPLIPALSIV 554
>BC062565-1|AAH62565.1| 635|Homo sapiens solute carrier family 7
(cationic amino acid transporter, y+ system), member 4
protein.
Length = 635
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 536 REDLFQIPMVPLIPALSIV 554
>BC008814-1|AAH08814.1| 635|Homo sapiens solute carrier family 7
(cationic amino acid transporter, y+ system), member 4
protein.
Length = 635
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 476 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 535
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 536 REDLFQIPMVPLIPALSIV 554
>AJ000730-1|CAA04263.1| 636|Homo sapiens cationic amino acid
transporter 3 protein.
Length = 636
Score = 32.3 bits (70), Expect = 4.9
Identities = 24/79 (30%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 129 AAATFLLRQVLNLAVTVYTPTVALHAVLALPHWASAAALTVVSIVFNL----LGGLAAAI 184
A T+ L +L A+T+ V ++ L LPHW L + S++F L LG
Sbjct: 477 AVVTWALGVMLASAITIGCVLVFGNSTLHLPHWGYILLLLLTSVMFLLSLLVLGAHQQQY 536
Query: 185 RADVIQTLTMILVSGAFIV 203
R D+ Q + L+ IV
Sbjct: 537 REDLFQIPMVPLIPALSIV 555
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.135 0.416
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 70,300,946
Number of Sequences: 224733
Number of extensions: 2371080
Number of successful extensions: 11303
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 11175
Number of HSP's gapped (non-prelim): 70
length of query: 581
length of database: 73,234,838
effective HSP length: 94
effective length of query: 487
effective length of database: 52,109,936
effective search space: 25377538832
effective search space used: 25377538832
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 68 (31.5 bits)
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