Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002321-TA|BGIBMGA002321-PA|undefined
(767 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86964-1|BAA13200.1| 1842|Homo sapiens KIAA0209 protein. 391 e-108
BC113457-1|AAI13458.1| 1830|Homo sapiens dedicator of cytokinesi... 391 e-108
BC104900-1|AAI04901.1| 1830|Homo sapiens dedicator of cytokinesi... 391 e-108
D50857-1|BAA09454.1| 1865|Homo sapiens DOCK180 protein protein. 382 e-105
BX470201-1|CAH72560.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
BX470155-1|CAI22477.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AL607029-1|CAI15329.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AL390920-1|CAH73231.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AL359094-1|CAH71477.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AL355316-1|CAI16871.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AL157711-1|CAH71463.2| 1865|Homo sapiens dedicator of cytokinesi... 382 e-105
AY254099-1|AAP80572.1| 2030|Homo sapiens DOCK3 protein. 262 4e-69
AY145303-1|AAN12301.1| 2030|Homo sapiens modifier of cell adhesi... 262 4e-69
AB002297-1|BAA20759.1| 1907|Homo sapiens KIAA0299 protein. 262 4e-69
BC117694-1|AAI17695.1| 1106|Homo sapiens DOCK4 protein protein. 255 5e-67
BC117688-1|AAI17689.1| 1966|Homo sapiens dedicator of cytokinesi... 255 5e-67
AY233380-1|AAO73565.1| 1966|Homo sapiens DOCK4 protein. 255 5e-67
BC117689-1|AAI17690.1| 2011|Homo sapiens DOCK4 protein protein. 252 5e-66
AK123607-1|BAC85660.1| 677|Homo sapiens protein ( Homo sapiens ... 140 2e-32
AB018259-1|BAA34436.3| 1388|Homo sapiens KIAA0716 protein protein. 112 4e-24
BC016996-1|AAH16996.1| 336|Homo sapiens DOCK2 protein protein. 95 8e-19
BC011877-1|AAH11877.1| 350|Homo sapiens DOCK5 protein protein. 81 2e-14
BC084559-1|AAH84559.1| 152|Homo sapiens DOCK1 protein protein. 60 2e-08
AB018326-1|BAA34503.2| 899|Homo sapiens KIAA0783 protein protein. 34 2.2
>D86964-1|BAA13200.1| 1842|Homo sapiens KIAA0209 protein.
Length = 1842
Score = 391 bits (962), Expect = e-108
Identities = 255/728 (35%), Positives = 399/728 (54%), Gaps = 60/728 (8%)
Query: 4 SRILLAPRTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNM--ETTPVTPNV 61
S+I + L+++L VR+ +G ++DP S L H+EA +I + + E + P+
Sbjct: 162 SKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITERIKEEMSKDQPDY 221
Query: 62 TP----AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-- 114
+ T ++ V V NFVCR+ + AEL +SL+D ++E+ L+RW + F
Sbjct: 222 AMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDPNKQTVISENYLVRWGSRGFPKE 281
Query: 115 -----TTNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGA 169
VVFTD G+ + +K+YL+C +VR+G MD ++ ++ +
Sbjct: 282 IEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQG----------- 330
Query: 170 MRRPFGVACADI----KRHLTSDNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAK 223
+RRPFGVA DI K SD +H +PF+ EN L +LL KV+A+ K
Sbjct: 331 LRRPFGVAVMDITDIIKGKAESDEEKQHF-IPFHPVTAENDFLHSLLGKVIAS---KGDS 386
Query: 224 HSQGLWVSIHLVEGDLKQIREENPHIVVNT-VVARKMGFPEVILPGDARNDLYVTLCXXX 282
QGLWV++ ++ GD+ QIR++ PH+V T VVARK+GFPE+I+PGD RND+Y+TL
Sbjct: 387 GGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGD 446
Query: 283 XXXXXXXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVF 342
+RN+E++ V + G+T+P I +GAG NEY S+VYY +PRW E
Sbjct: 447 FDKYNKTT-QRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETV 505
Query: 343 KVCLNIEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYK 402
KV + IE+ + HL F+ RHRSS E+KD+ E++FA+++++LM+ +GTT D H+L V K
Sbjct: 506 KVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLK 565
Query: 403 IDNKRSNPAEVEKEAAAVCLGLPSKRDELP-AGA---ERGLTRGVLSLIHRDTLTVATKL 458
D+K+ E A+ L LPS R + GA + G LS+ RD +++T +
Sbjct: 566 GDSKK-------MEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLV 618
Query: 459 CSTKLTQKEEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVE 518
CSTKLTQ +LG+LKW P L+ L +L V EE+VKFLQD LD LF+I+ +
Sbjct: 619 CSTKLTQNVGLLGLLKW--RMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHS 676
Query: 519 EDQEYYSDKSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMV 578
+ E Y +LVF+ L+ +I L+AD K+QHF VL YI + F LAY+ L+TV+
Sbjct: 677 QSDE------YDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLK 730
Query: 579 WVIRTANSSEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEAL 638
+ T++ E + +L +K L + F+ L E++
Sbjct: 731 TYLDTSSRGEQC-EPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESI 789
Query: 639 VWLMRCG-EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYII-RALDALPLCRLGTQRM 696
LM+ + + Q +ALKY P +V H +++ D +L + ++ +P +L Q++
Sbjct: 790 NNLMKSQYKTTILLQVAALKYIP-SVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKV 848
Query: 697 LALLELVR 704
++ E+V+
Sbjct: 849 QSMNEIVQ 856
>BC113457-1|AAI13458.1| 1830|Homo sapiens dedicator of cytokinesis 2
protein.
Length = 1830
Score = 391 bits (962), Expect = e-108
Identities = 255/728 (35%), Positives = 399/728 (54%), Gaps = 60/728 (8%)
Query: 4 SRILLAPRTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNM--ETTPVTPNV 61
S+I + L+++L VR+ +G ++DP S L H+EA +I + + E + P+
Sbjct: 150 SKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITERIKEEMSKDQPDY 209
Query: 62 TP----AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-- 114
+ T ++ V V NFVCR+ + AEL +SL+D ++E+ L+RW + F
Sbjct: 210 AMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDPNKQTVISENYLVRWGSRGFPKE 269
Query: 115 -----TTNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGA 169
VVFTD G+ + +K+YL+C +VR+G MD ++ ++ +
Sbjct: 270 IEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQG----------- 318
Query: 170 MRRPFGVACADI----KRHLTSDNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAK 223
+RRPFGVA DI K SD +H +PF+ EN L +LL KV+A+ K
Sbjct: 319 LRRPFGVAVMDITDIIKGKAESDEEKQHF-IPFHPVTAENDFLHSLLGKVIAS---KGDS 374
Query: 224 HSQGLWVSIHLVEGDLKQIREENPHIVVNT-VVARKMGFPEVILPGDARNDLYVTLCXXX 282
QGLWV++ ++ GD+ QIR++ PH+V T VVARK+GFPE+I+PGD RND+Y+TL
Sbjct: 375 GGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGD 434
Query: 283 XXXXXXXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVF 342
+RN+E++ V + G+T+P I +GAG NEY S+VYY +PRW E
Sbjct: 435 FDKYNKTT-QRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETV 493
Query: 343 KVCLNIEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYK 402
KV + IE+ + HL F+ RHRSS E+KD+ E++FA+++++LM+ +GTT D H+L V K
Sbjct: 494 KVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLK 553
Query: 403 IDNKRSNPAEVEKEAAAVCLGLPSKRDELP-AGA---ERGLTRGVLSLIHRDTLTVATKL 458
D+K+ E A+ L LPS R + GA + G LS+ RD +++T +
Sbjct: 554 GDSKK-------MEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLV 606
Query: 459 CSTKLTQKEEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVE 518
CSTKLTQ +LG+LKW P L+ L +L V EE+VKFLQD LD LF+I+ +
Sbjct: 607 CSTKLTQNVGLLGLLKW--RMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHS 664
Query: 519 EDQEYYSDKSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMV 578
+ E Y +LVF+ L+ +I L+AD K+QHF VL YI + F LAY+ L+TV+
Sbjct: 665 QSDE------YDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLK 718
Query: 579 WVIRTANSSEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEAL 638
+ T++ E + +L +K L + F+ L E++
Sbjct: 719 TYLDTSSRGEQC-EPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESI 777
Query: 639 VWLMRCG-EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYII-RALDALPLCRLGTQRM 696
LM+ + + Q +ALKY P +V H +++ D +L + ++ +P +L Q++
Sbjct: 778 NNLMKSQYKTTILLQVAALKYIP-SVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKV 836
Query: 697 LALLELVR 704
++ E+V+
Sbjct: 837 QSMNEIVQ 844
>BC104900-1|AAI04901.1| 1830|Homo sapiens dedicator of cytokinesis 2
protein.
Length = 1830
Score = 391 bits (962), Expect = e-108
Identities = 255/728 (35%), Positives = 399/728 (54%), Gaps = 60/728 (8%)
Query: 4 SRILLAPRTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNM--ETTPVTPNV 61
S+I + L+++L VR+ +G ++DP S L H+EA +I + + E + P+
Sbjct: 150 SKIDYGNKILELDLIVRDEDGNILDPDNTSVISLFHAHEEATDKITERIKEEMSKDQPDY 209
Query: 62 TP----AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-- 114
+ T ++ V V NFVCR+ + AEL +SL+D ++E+ L+RW + F
Sbjct: 210 AMYSRISSSPTHSLYVFVRNFVCRIGEDAELFMSLYDPNKQTVISENYLVRWGSRGFPKE 269
Query: 115 -----TTNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGA 169
VVFTD G+ + +K+YL+C +VR+G MD ++ ++ +
Sbjct: 270 IEMLNNLKVVFTDLGNKDLNRDKIYLICQIVRVGKMDLKDTGAKKCTQG----------- 318
Query: 170 MRRPFGVACADI----KRHLTSDNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAK 223
+RRPFGVA DI K SD +H +PF+ EN L +LL KV+A+ K
Sbjct: 319 LRRPFGVAVMDITDIIKGKAESDEEKQHF-IPFHPVTAENDFLHSLLGKVIAS---KGDS 374
Query: 224 HSQGLWVSIHLVEGDLKQIREENPHIVVNT-VVARKMGFPEVILPGDARNDLYVTLCXXX 282
QGLWV++ ++ GD+ QIR++ PH+V T VVARK+GFPE+I+PGD RND+Y+TL
Sbjct: 375 GGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPGDVRNDIYITLLQGD 434
Query: 283 XXXXXXXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVF 342
+RN+E++ V + G+T+P I +GAG NEY S+VYY +PRW E
Sbjct: 435 FDKYNKTT-QRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVVYYQVKQPRWMETV 493
Query: 343 KVCLNIEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYK 402
KV + IE+ + HL F+ RHRSS E+KD+ E++FA+++++LM+ +GTT D H+L V K
Sbjct: 494 KVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLK 553
Query: 403 IDNKRSNPAEVEKEAAAVCLGLPSKRDELP-AGA---ERGLTRGVLSLIHRDTLTVATKL 458
D+K+ E A+ L LPS R + GA + G LS+ RD +++T +
Sbjct: 554 GDSKK-------MEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLV 606
Query: 459 CSTKLTQKEEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVE 518
CSTKLTQ +LG+LKW P L+ L +L V EE+VKFLQD LD LF+I+ +
Sbjct: 607 CSTKLTQNVGLLGLLKW--RMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIMMEHS 664
Query: 519 EDQEYYSDKSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMV 578
+ E Y +LVF+ L+ +I L+AD K+QHF VL YI + F LAY+ L+TV+
Sbjct: 665 QSDE------YDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLK 718
Query: 579 WVIRTANSSEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEAL 638
+ T++ E + +L +K L + F+ L E++
Sbjct: 719 TYLDTSSRGEQC-EPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESI 777
Query: 639 VWLMRCG-EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYII-RALDALPLCRLGTQRM 696
LM+ + + Q +ALKY P +V H +++ D +L + ++ +P +L Q++
Sbjct: 778 NNLMKSQYKTTILLQVAALKYIP-SVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKV 836
Query: 697 LALLELVR 704
++ E+V+
Sbjct: 837 QSMNEIVQ 844
>D50857-1|BAA09454.1| 1865|Homo sapiens DOCK180 protein protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>BX470201-1|CAH72560.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>BX470155-1|CAI22477.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AL607029-1|CAI15329.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AL390920-1|CAH73231.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AL359094-1|CAH71477.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AL355316-1|CAI16871.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AL157711-1|CAH71463.2| 1865|Homo sapiens dedicator of cytokinesis 1
protein.
Length = 1865
Score = 382 bits (939), Expect = e-105
Identities = 242/718 (33%), Positives = 378/718 (52%), Gaps = 55/718 (7%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRIDKNME-------TTPVTPNVTP 63
R LD++L VR+ +G ++DP ST L H+ A+ ++++ ++ +
Sbjct: 158 RILDLDLVVRDEDGNILDPELTSTISLFRAHEIASKQVEERLQEEKSQKQNIDINRQAKF 217
Query: 64 AGVRTFTVCVRVHNFVCRVADVAELSLSLHDAAGNK-LTEHLLIRWPTPNFA-------T 115
A + + V + N VC++ + AE+ +SL+D +K ++E+ L+RW +
Sbjct: 218 AATPSLALFVNLKNVVCKIGEDAEVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHN 277
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD GS +K EK+ VC +VR+G M+ ++ + R+ + +RRPFG
Sbjct: 278 LRAVFTDLGSKDLKREKISFVCQIVRVGRMELRDNNTRKLT-----------SGLRRPFG 326
Query: 176 VACADIKRHLTS--DNPDKHIQVPFYAYEKEN--LDALLKKVMANRELKDAKHSQGLWVS 231
VA D+ + D+ DK +PF EN L ++ KV+A +E+ QGLWV+
Sbjct: 327 VAVMDVTDIINGKVDDEDKQHFIPFQPVAGENDFLQTVINKVIAAKEVNHK--GQGLWVT 384
Query: 232 IHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXX 290
+ L+ GD+ QIR+E PH+V T VARK GFPE+I+PGD RND+YVTL
Sbjct: 385 LKLLPGDIHQIRKEFPHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTT 444
Query: 291 XERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEE 350
+N+E+ V D+ G+ + VI GAG +EY S++YY +PRW E KV + IE+
Sbjct: 445 A-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKSVIYYQVKQPRWFETVKVAIPIED 503
Query: 351 FKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNP 410
+HL F RHRSS ++KD++E+ FALAF++LM+ +GTT D H+L VYK + K+
Sbjct: 504 VNRSHLRFTFRHRSSQDSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKK--- 560
Query: 411 AEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSL----IHRDTLTVATKLCSTKLTQK 466
E AA L LPS + EL + + SL I +D+ ++T +CSTKLTQ
Sbjct: 561 ----LEDAATYLSLPSTKAELEEKGHSATGKSMQSLGSCTISKDSFQISTLVCSTKLTQN 616
Query: 467 EEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSD 526
++LG+LKW ++ + L+ L QL+ V E+VKFLQD LD LF+I+ + E +
Sbjct: 617 VDLLGLLKWRSNTS--LLQQNLRQLMKVDGGEVVKFLQDTLDALFNIMMENSESE----- 669
Query: 527 KSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANS 586
++ LVF+ L+ +I L+AD K+QHF PVL YI + F LAY L V+ + A
Sbjct: 670 -TFDTLVFDALVFIIGLIADRKFQHFNPVLETYIKKHFSATLAYTKLTKVLKNYVDGA-E 727
Query: 587 SEAAVKRLLVCMKCXXXXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM-RCG 645
++L MK L ++ + F L ++ +M
Sbjct: 728 KPGVNEQLYKAMKALESIFKFIVRSRILFNQLYENKGEADFVESLLQLFRSINDMMSSMS 787
Query: 646 EHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIRALDALPLCRLGTQRMLALLELV 703
+ + +G+ALKY P V + V+ EL + +P+ L Q++ L+E+V
Sbjct: 788 DQTVRVKGAALKYLPTIVNDVKLVFDPKELSKMFTEFILNVPMGLLTIQKLYCLIEIV 845
>AY254099-1|AAP80572.1| 2030|Homo sapiens DOCK3 protein.
Length = 2030
Score = 262 bits (641), Expect = 4e-69
Identities = 193/629 (30%), Positives = 309/629 (49%), Gaps = 60/629 (9%)
Query: 82 VADVAELSLSLHDAA-GNKLTEHLLIRWPTPNFATTN--------VVFTDFGSDFMKNEK 132
+ + ++ SL+D G +++E L+R N N +FTD S MK +
Sbjct: 229 IGEDTDVFFSLYDMREGKQISERFLVRL-NKNGGPRNPEKIERMCALFTDLSSKDMKRD- 286
Query: 133 VYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFGVACA---DIKRHLTSDN 189
+Y+V HV+RIG M + S P + RRP+G A D+ + LT
Sbjct: 287 LYIVAHVIRIGRMLLND------SKKGPPHLH-----YRRPYGCAVLSILDVLQSLTEVK 335
Query: 190 PDKHIQVPFYAYEKENL-----DALLKKVMANRELKDAKHSQGLWVSIHLVEGDLKQIRE 244
+K + Y E+ + +++K A A H GL +S+ L+ GD++QIR
Sbjct: 336 EEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSAPSASH--GLIISLQLLRGDMEQIRR 393
Query: 245 ENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXXXERNIELVARVVD 303
ENP I + + RK+GFP+VI+PGD RNDLY+TL ++NIE+ V+
Sbjct: 394 ENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTL-EKGDFERGGKSVQKNIEVTMYVLY 452
Query: 304 QHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEEFKDAHLVFLCRHR 363
G + IS+G+G P + Y S V YH + PRW E+ K+ + I+ F+ +HL F RH
Sbjct: 453 ADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHC 512
Query: 364 SSNEAKDRAERH-FALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNPAEVEKEAAAVCL 422
S+ KD+ E+ F AF LM+ +GTT D H L VYK D + A+ L
Sbjct: 513 ST---KDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENST------FNNHALYL 563
Query: 423 GLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKEEILGVLKWSTHRTPG 482
GLP +++ G + + +++ ++T+L STKLTQ ++L +LKW P
Sbjct: 564 GLPCCKEDY-NGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAF--PD 620
Query: 483 TLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDKSYGVLVFECLLRVIS 542
+ L +L HV EE+VKFLQDILDTLF IL + + YG+LVF+ L+ +I+
Sbjct: 621 RIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDD--------NTEKYGLLVFQSLVFIIN 672
Query: 543 LVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSSEAAVKRLLVCMKCXX 602
L+ D KY HF+PV+ YI + F ALAY+ LI + W + ++ + M+
Sbjct: 673 LLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYM-DCSAELIRQDHIQEAMRALE 731
Query: 603 XXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM----RCGEHVLTCQGSALKY 658
++ F++ L +++ +++ R E +L Q + L
Sbjct: 732 YLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNS 791
Query: 659 FPHAVPHIIKVYPDTELCAYIIRALDALP 687
FP +++++ E+ ++ L ++P
Sbjct: 792 FPTIFDELLQMFTVQEVAEFVRGTLGSMP 820
>AY145303-1|AAN12301.1| 2030|Homo sapiens modifier of cell adhesion
protein.
Length = 2030
Score = 262 bits (641), Expect = 4e-69
Identities = 193/629 (30%), Positives = 309/629 (49%), Gaps = 60/629 (9%)
Query: 82 VADVAELSLSLHDAA-GNKLTEHLLIRWPTPNFATTN--------VVFTDFGSDFMKNEK 132
+ + ++ SL+D G +++E L+R N N +FTD S MK +
Sbjct: 229 IGEDTDVFFSLYDMREGKQISERFLVRL-NKNGGPRNPEKIERMCALFTDLSSKDMKRD- 286
Query: 133 VYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFGVACA---DIKRHLTSDN 189
+Y+V HV+RIG M + S P + RRP+G A D+ + LT
Sbjct: 287 LYIVAHVIRIGRMLLND------SKKGPPHLH-----YRRPYGCAVLSILDVLQSLTEVK 335
Query: 190 PDKHIQVPFYAYEKENL-----DALLKKVMANRELKDAKHSQGLWVSIHLVEGDLKQIRE 244
+K + Y E+ + +++K A A H GL +S+ L+ GD++QIR
Sbjct: 336 EEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSAPSASH--GLIISLQLLRGDMEQIRR 393
Query: 245 ENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXXXERNIELVARVVD 303
ENP I + + RK+GFP+VI+PGD RNDLY+TL ++NIE+ V+
Sbjct: 394 ENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTL-EKGDFERGGKSVQKNIEVTMYVLY 452
Query: 304 QHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEEFKDAHLVFLCRHR 363
G + IS+G+G P + Y S V YH + PRW E+ K+ + I+ F+ +HL F RH
Sbjct: 453 ADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHC 512
Query: 364 SSNEAKDRAERH-FALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNPAEVEKEAAAVCL 422
S+ KD+ E+ F AF LM+ +GTT D H L VYK D + A+ L
Sbjct: 513 ST---KDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENST------FNNHALYL 563
Query: 423 GLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKEEILGVLKWSTHRTPG 482
GLP +++ G + + +++ ++T+L STKLTQ ++L +LKW P
Sbjct: 564 GLPCCKEDY-NGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAF--PD 620
Query: 483 TLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDKSYGVLVFECLLRVIS 542
+ L +L HV EE+VKFLQDILDTLF IL + + YG+LVF+ L+ +I+
Sbjct: 621 RIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDD--------NTEKYGLLVFQSLVFIIN 672
Query: 543 LVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSSEAAVKRLLVCMKCXX 602
L+ D KY HF+PV+ YI + F ALAY+ LI + W + ++ + M+
Sbjct: 673 LLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYM-DCSAELIRQDHIQEAMRALE 731
Query: 603 XXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM----RCGEHVLTCQGSALKY 658
++ F++ L +++ +++ R E +L Q + L
Sbjct: 732 YLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNS 791
Query: 659 FPHAVPHIIKVYPDTELCAYIIRALDALP 687
FP +++++ E+ ++ L ++P
Sbjct: 792 FPTIFDELLQMFTVQEVAEFVRGTLGSMP 820
>AB002297-1|BAA20759.1| 1907|Homo sapiens KIAA0299 protein.
Length = 1907
Score = 262 bits (641), Expect = 4e-69
Identities = 193/629 (30%), Positives = 309/629 (49%), Gaps = 60/629 (9%)
Query: 82 VADVAELSLSLHDAA-GNKLTEHLLIRWPTPNFATTN--------VVFTDFGSDFMKNEK 132
+ + ++ SL+D G +++E L+R N N +FTD S MK +
Sbjct: 106 IGEDTDVFFSLYDMREGKQISERFLVRL-NKNGGPRNPEKIERMCALFTDLSSKDMKRD- 163
Query: 133 VYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFGVACA---DIKRHLTSDN 189
+Y+V HV+RIG M + S P + RRP+G A D+ + LT
Sbjct: 164 LYIVAHVIRIGRMLLND------SKKGPPHLH-----YRRPYGCAVLSILDVLQSLTEVK 212
Query: 190 PDKHIQVPFYAYEKENL-----DALLKKVMANRELKDAKHSQGLWVSIHLVEGDLKQIRE 244
+K + Y E+ + +++K A A H GL +S+ L+ GD++QIR
Sbjct: 213 EEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSAPSASH--GLIISLQLLRGDMEQIRR 270
Query: 245 ENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXXXXXXERNIELVARVVD 303
ENP I + + RK+GFP+VI+PGD RNDLY+TL ++NIE+ V+
Sbjct: 271 ENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTL-EKGDFERGGKSVQKNIEVTMYVLY 329
Query: 304 QHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLNIEEFKDAHLVFLCRHR 363
G + IS+G+G P + Y S V YH + PRW E+ K+ + I+ F+ +HL F RH
Sbjct: 330 ADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHC 389
Query: 364 SSNEAKDRAERH-FALAFLRLMQREGTTTPDTNHNLCVYKIDNKRSNPAEVEKEAAAVCL 422
S+ KD+ E+ F AF LM+ +GTT D H L VYK D + A+ L
Sbjct: 390 ST---KDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENST------FNNHALYL 440
Query: 423 GLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKEEILGVLKWSTHRTPG 482
GLP +++ G + + +++ ++T+L STKLTQ ++L +LKW P
Sbjct: 441 GLPCCKEDY-NGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAF--PD 497
Query: 483 TLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDKSYGVLVFECLLRVIS 542
+ L +L HV EE+VKFLQDILDTLF IL + + YG+LVF+ L+ +I+
Sbjct: 498 RIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDD--------NTEKYGLLVFQSLVFIIN 549
Query: 543 LVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSSEAAVKRLLVCMKCXX 602
L+ D KY HF+PV+ YI + F ALAY+ LI + W + ++ + M+
Sbjct: 550 LLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYM-DCSAELIRQDHIQEAMRALE 608
Query: 603 XXXXXXXXXXXXXXALGDSAADDGFKALFDTLLEALVWLM----RCGEHVLTCQGSALKY 658
++ F++ L +++ +++ R E +L Q + L
Sbjct: 609 YLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNS 668
Query: 659 FPHAVPHIIKVYPDTELCAYIIRALDALP 687
FP +++++ E+ ++ L ++P
Sbjct: 669 FPTIFDELLQMFTVQEVAEFVRGTLGSMP 697
>BC117694-1|AAI17695.1| 1106|Homo sapiens DOCK4 protein protein.
Length = 1106
Score = 255 bits (624), Expect = 5e-67
Identities = 171/541 (31%), Positives = 280/541 (51%), Gaps = 54/541 (9%)
Query: 62 TPAGVRTFTVCVRVHNFVC-RVADVAELSLSLHDAAGNK-LTEHLLIRW------PTPNF 113
TP + + V++ + +C + + E+ SL D+ N+ ++E +R P+
Sbjct: 193 TPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNRNGLPKAPDK 252
Query: 114 ATTNV-VFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRR 172
+ +F D GS ++ + +Y+ H++RIG M A + + + Q RR
Sbjct: 253 PERHCSLFVDLGSSELRKD-IYITVHIIRIGRMGAG--EKKNACSVQ----------YRR 299
Query: 173 PFGVACADIKRHLTSDNPDKHIQVPFYAYEKENL----DALLKKVMANRELKDAKHSQGL 228
PFG A I LT + D I + + + ++KK+ A L + + GL
Sbjct: 300 PFGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHENIIKKLNARYNLTGS--NAGL 357
Query: 229 WVSIHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXX 287
VS+ L+ GD++QIR E + + V + RK+GF +I+PG+ RNDLY+T+
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITI-ERGEFEKG 416
Query: 288 XXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLN 347
RN+E+ +VD G+T+ IS G+G P A+EY S V YH++ PRW E+ K+ +
Sbjct: 417 GKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIP 476
Query: 348 IEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKR 407
+++F+ AH+ F RH S+ E ++ + F +F+ LMQ +G T PD H L V+K + +
Sbjct: 477 VDKFRGAHIRFEFRHCSTKEKGEK--KLFGFSFVPLMQEDGRTLPDGTHELIVHKCE-EN 533
Query: 408 SNPAEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKE 467
+N + + L LP + G G + +++ + + LCSTKLTQ
Sbjct: 534 TNLQDTTR-----YLKLPFSK-----GIFLGNNNQAMKAT-KESFCITSFLCSTKLTQNG 582
Query: 468 EILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDK 527
++L +LKW TH P + L++L + E+VKFLQD LDTLF IL + + +
Sbjct: 583 DMLDLLKWRTH--PDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDE--------NSQ 632
Query: 528 SYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSS 587
YG VF+ L+ +I+L+ D K+ HF+PV+ YI+ F ALAY LI V+ W + +
Sbjct: 633 KYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEA 692
Query: 588 E 588
E
Sbjct: 693 E 693
>BC117688-1|AAI17689.1| 1966|Homo sapiens dedicator of cytokinesis 4
protein.
Length = 1966
Score = 255 bits (624), Expect = 5e-67
Identities = 171/541 (31%), Positives = 280/541 (51%), Gaps = 54/541 (9%)
Query: 62 TPAGVRTFTVCVRVHNFVC-RVADVAELSLSLHDAAGNK-LTEHLLIRW------PTPNF 113
TP + + V++ + +C + + E+ SL D+ N+ ++E +R P+
Sbjct: 193 TPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNRNGLPKAPDK 252
Query: 114 ATTNV-VFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRR 172
+ +F D GS ++ + +Y+ H++RIG M A + + + Q RR
Sbjct: 253 PERHCSLFVDLGSSELRKD-IYITVHIIRIGRMGAG--EKKNACSVQ----------YRR 299
Query: 173 PFGVACADIKRHLTSDNPDKHIQVPFYAYEKENL----DALLKKVMANRELKDAKHSQGL 228
PFG A I LT + D I + + + ++KK+ A L + + GL
Sbjct: 300 PFGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHENIIKKLNARYNLTGS--NAGL 357
Query: 229 WVSIHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXX 287
VS+ L+ GD++QIR E + + V + RK+GF +I+PG+ RNDLY+T+
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITI-ERGEFEKG 416
Query: 288 XXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLN 347
RN+E+ +VD G+T+ IS G+G P A+EY S V YH++ PRW E+ K+ +
Sbjct: 417 GKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIP 476
Query: 348 IEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKR 407
+++F+ AH+ F RH S+ E ++ + F +F+ LMQ +G T PD H L V+K + +
Sbjct: 477 VDKFRGAHIRFEFRHCSTKEKGEK--KLFGFSFVPLMQEDGRTLPDGTHELIVHKCE-EN 533
Query: 408 SNPAEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKE 467
+N + + L LP + G G + +++ + + LCSTKLTQ
Sbjct: 534 TNLQDTTR-----YLKLPFSK-----GIFLGNNNQAMKAT-KESFCITSFLCSTKLTQNG 582
Query: 468 EILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDK 527
++L +LKW TH P + L++L + E+VKFLQD LDTLF IL + + +
Sbjct: 583 DMLDLLKWRTH--PDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDE--------NSQ 632
Query: 528 SYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSS 587
YG VF+ L+ +I+L+ D K+ HF+PV+ YI+ F ALAY LI V+ W + +
Sbjct: 633 KYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEA 692
Query: 588 E 588
E
Sbjct: 693 E 693
>AY233380-1|AAO73565.1| 1966|Homo sapiens DOCK4 protein.
Length = 1966
Score = 255 bits (624), Expect = 5e-67
Identities = 171/541 (31%), Positives = 280/541 (51%), Gaps = 54/541 (9%)
Query: 62 TPAGVRTFTVCVRVHNFVC-RVADVAELSLSLHDAAGNK-LTEHLLIRW------PTPNF 113
TP + + V++ + +C + + E+ SL D+ N+ ++E +R P+
Sbjct: 193 TPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNRNGLPKAPDK 252
Query: 114 ATTNV-VFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRR 172
+ +F D GS ++ + +Y+ H++RIG M A + + + Q RR
Sbjct: 253 PERHCSLFVDLGSSELRKD-IYITVHIIRIGRMGAG--EKKNACSVQ----------YRR 299
Query: 173 PFGVACADIKRHLTSDNPDKHIQVPFYAYEKENL----DALLKKVMANRELKDAKHSQGL 228
PFG A I LT + D I + + + ++KK+ A L + + GL
Sbjct: 300 PFGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHENIIKKLNARYNLTGS--NAGL 357
Query: 229 WVSIHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXX 287
VS+ L+ GD++QIR E + + V + RK+GF +I+PG+ RNDLY+T+
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITI-ERGEFEKG 416
Query: 288 XXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLN 347
RN+E+ +VD G+T+ IS G+G P A+EY S V YH++ PRW E+ K+ +
Sbjct: 417 GKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIP 476
Query: 348 IEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKR 407
+++F+ AH+ F RH S+ E ++ + F +F+ LMQ +G T PD H L V+K + +
Sbjct: 477 VDKFRGAHIRFEFRHCSTKEKGEK--KLFGFSFVPLMQEDGRTLPDGTHELIVHKCE-EN 533
Query: 408 SNPAEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKE 467
+N + + L LP + G G + +++ + + LCSTKLTQ
Sbjct: 534 TNLQDTTR-----YLKLPFSK-----GIFLGNNNQAMKAT-KESFCITSFLCSTKLTQNG 582
Query: 468 EILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDK 527
++L +LKW TH P + L++L + E+VKFLQD LDTLF IL + + +
Sbjct: 583 DMLDLLKWRTH--PDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDE--------NSQ 632
Query: 528 SYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSS 587
YG VF+ L+ +I+L+ D K+ HF+PV+ YI+ F ALAY LI V+ W + +
Sbjct: 633 KYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEA 692
Query: 588 E 588
E
Sbjct: 693 E 693
>BC117689-1|AAI17690.1| 2011|Homo sapiens DOCK4 protein protein.
Length = 2011
Score = 252 bits (616), Expect = 5e-66
Identities = 170/541 (31%), Positives = 279/541 (51%), Gaps = 54/541 (9%)
Query: 62 TPAGVRTFTVCVRVHNFVC-RVADVAELSLSLHDAAGNK-LTEHLLIRW------PTPNF 113
TP + + V++ + +C + + E+ SL D+ N+ ++E +R P+
Sbjct: 193 TPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNRNGLPKAPDK 252
Query: 114 ATTNV-VFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRR 172
+ +F D GS ++ + +Y+ H++RIG M A + + + Q RR
Sbjct: 253 PERHCSLFVDLGSSELRKD-IYITVHIIRIGRMGAG--EKKNACSVQ----------YRR 299
Query: 173 PFGVACADIKRHLTSDNPDKHIQVPFYAYEKENL----DALLKKVMANRELKDAKHSQGL 228
PFG A I LT + D I + + + ++KK+ A L + + GL
Sbjct: 300 PFGCAVLSIADLLTGETKDDLILKVYMCNTESEWYQIHENIIKKLNARYNLTGS--NAGL 357
Query: 229 WVSIHLVEGDLKQIREENPHIVVNTV-VARKMGFPEVILPGDARNDLYVTLCXXXXXXXX 287
VS+ L+ GD++QIR E + + V + RK+GF +I+PG+ RNDLY+T+
Sbjct: 358 AVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITI-ERGEFEKG 416
Query: 288 XXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTSLVYYHDDRPRWQEVFKVCLN 347
RN+E+ +VD G+T+ IS G+G P A+EY S V YH++ PRW E+ K+ +
Sbjct: 417 GKSVARNVEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIP 476
Query: 348 IEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKIDNKR 407
+++F+ AH+ F R S+ E ++ + F +F+ LMQ +G T PD H L V+K + +
Sbjct: 477 VDKFRGAHIRFEFRRCSTKEKGEK--KLFGFSFVPLMQEDGRTLPDGTHELIVHKCE-EN 533
Query: 408 SNPAEVEKEAAAVCLGLPSKRDELPAGAERGLTRGVLSLIHRDTLTVATKLCSTKLTQKE 467
+N + + L LP + G G + +++ + + LCSTKLTQ
Sbjct: 534 TNLQDTTR-----YLKLPFSK-----GIFLGNNNQAMKAT-KESFCITSFLCSTKLTQNG 582
Query: 468 EILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILDTLFSILTQVEEDQEYYSDK 527
++L +LKW TH P + L++L + E+VKFLQD LDTLF IL + + +
Sbjct: 583 DMLDLLKWRTH--PDKITGCLSKLKEIDGSEIVKFLQDTLDTLFGILDE--------NSQ 632
Query: 528 SYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDALAYESLITVMVWVIRTANSS 587
YG VF+ L+ +I+L+ D K+ HF+PV+ YI+ F ALAY LI V+ W + +
Sbjct: 633 KYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEA 692
Query: 588 E 588
E
Sbjct: 693 E 693
>AK123607-1|BAC85660.1| 677|Homo sapiens protein ( Homo sapiens
cDNA FLJ41613 fis, clone CTONG3002412, moderately
similar to Human DOCK180 protein mRNA. ).
Length = 677
Score = 140 bits (339), Expect = 2e-32
Identities = 99/322 (30%), Positives = 158/322 (49%), Gaps = 14/322 (4%)
Query: 384 MQREGTTTPDTNHNLCVYKIDNKRSNPAEVEKEAAAVCLGLPSKRDELPAGAERGLTRGV 443
M +GTT D H+L VYK DNK+ A+ + + K EL A ++ +T
Sbjct: 1 MNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEK--ELQA-SKNLVTFTP 57
Query: 444 LSLIHRDTLTVATKLCSTKLTQKEEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFL 503
+D+ +AT +CSTKLTQ ++LG+L W ++ ++ L +L+ V E+VKFL
Sbjct: 58 SKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQ--NIKHNLKKLMEVDGGEIVKFL 115
Query: 504 QDILDTLFSILTQVEEDQEYYSDKSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDES 563
QD LD LF+I+ ++ + + +Y LVF+ L+ +ISL+ D K+QHF PVL YI +
Sbjct: 116 QDTLDALFNIMMEMSDSE------TYDFLVFDALVFIISLIGDIKFQHFNPVLETYIYKH 169
Query: 564 FCDALAYESLITVMVWVIRTANSSEAAVKRLLVCMKCXXXXXXXXXXXXXXXXAL-GDSA 622
F LAY L V+ + + A+ S + + L +K G S
Sbjct: 170 FSATLAYVKLSKVLNFYVANADDS-SKTELLFAALKALKYLFRFIIQSRVLYLRFYGQSK 228
Query: 623 ADDGFKALFDTLLEALVWLM-RCGEHVLTCQGSALKYFPHAVPHIIKVYPDTELCAYIIR 681
D F L A LM R E + +G+ALKY P + + V+ EL +
Sbjct: 229 DGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLFCK 288
Query: 682 ALDALPLCRLGTQRMLALLELV 703
+ ++P +L Q++ + ++V
Sbjct: 289 FIQSIPDNQLVRQKLNCMTKIV 310
>AB018259-1|BAA34436.3| 1388|Homo sapiens KIAA0716 protein protein.
Length = 1388
Score = 112 bits (270), Expect = 4e-24
Identities = 56/140 (40%), Positives = 84/140 (60%), Gaps = 10/140 (7%)
Query: 449 RDTLTVATKLCSTKLTQKEEILGVLKWSTHRTPGTLRPALTQLLHVPSEELVKFLQDILD 508
+++ + + LCSTKLTQ ++L +LKW TH P + L++L + E+VKFLQD LD
Sbjct: 15 KESFCITSFLCSTKLTQNGDMLDLLKWRTH--PDKITGCLSKLKEIDGSEIVKFLQDTLD 72
Query: 509 TLFSILTQVEEDQEYYSDKSYGVLVFECLLRVISLVADHKYQHFQPVLHVYIDESFCDAL 568
TLF IL + + + YG VF+ L+ +I+L+ D K+ HF+PV+ YI+ F AL
Sbjct: 73 TLFGILDE--------NSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGAL 124
Query: 569 AYESLITVMVWVIRTANSSE 588
AY LI V+ W + +E
Sbjct: 125 AYRDLIKVLKWYVDRITEAE 144
>BC016996-1|AAH16996.1| 336|Homo sapiens DOCK2 protein protein.
Length = 336
Score = 95.1 bits (226), Expect = 8e-19
Identities = 56/136 (41%), Positives = 84/136 (61%), Gaps = 11/136 (8%)
Query: 344 VCLNIEEFKDAHLVFLCRHRSSNEAKDRAERHFALAFLRLMQREGTTTPDTNHNLCVYKI 403
V + IE+ + HL F+ RHRSS E+KD+ E++FA+++++LM+ +GTT D H+L V K
Sbjct: 13 VAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGTTLHDGFHDLVVLKG 72
Query: 404 DNKRSNPAEVEKEAAAVCLGLPSKRDELP-AGA---ERGLTRGVLSLIHRDTLTVATKLC 459
D+K+ E A+ L LPS R + GA + G LS+ RD +++T +C
Sbjct: 73 DSKK-------MEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVFSISTLVC 125
Query: 460 STKLTQKEEILGVLKW 475
STKLTQ +LG+LKW
Sbjct: 126 STKLTQNVGLLGLLKW 141
>BC011877-1|AAH11877.1| 350|Homo sapiens DOCK5 protein protein.
Length = 350
Score = 80.6 bits (190), Expect = 2e-14
Identities = 64/205 (31%), Positives = 98/205 (47%), Gaps = 30/205 (14%)
Query: 11 RTLDMELAVRNSNGQLVDPLKMSTYRLNALHDEANTRI-DKNMETTPVTPNVTPAG---- 65
R L ++L VR+ NG ++DP + ST L H+ A+ RI +K E + N+ G
Sbjct: 157 RMLGLDLVVRDDNGNILDPDETSTIALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIF 216
Query: 66 --VRTFTVCVRVHNFVCRVADVAELSLSLHDA-AGNKLTEHLLIRWPT-------PNFAT 115
+ T+ + V NFVC + + AEL ++L+D ++E+ LIRW +
Sbjct: 217 STIHTYGLYVNFKNFVCNIGEDAELFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNN 276
Query: 116 TNVVFTDFGSDFMKNEKVYLVCHVVRIGSMDAQNVDHRRSSVAQPVSMSTSAGAMRRPFG 175
VFTD S + +V LVC +VR+G M+ + + G +RRPFG
Sbjct: 277 LQAVFTDLSSMDLIRPRVSLVCQIVRVGHMELKE------------GKKHTCG-LRRPFG 323
Query: 176 VACADIKR--HLTSDNPDKHIQVPF 198
VA DI H D+ +K +PF
Sbjct: 324 VAVMDITDIIHGKVDDEEKQHFIPF 348
>BC084559-1|AAH84559.1| 152|Homo sapiens DOCK1 protein protein.
Length = 152
Score = 60.5 bits (140), Expect = 2e-08
Identities = 30/77 (38%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 268 GDARNDLYVTLCXXXXXXXXXXXXERNIELVARVVDQHGRTIPGVISIGAGVPLANEYTS 327
GD RND+YVTL +N+E+ V D+ G+ + VI GAG +EY S
Sbjct: 30 GDVRNDIYVTLVQGDFDKGSKTTA-KNVEVTVSVYDEDGKRLEHVIFPGAGDEAISEYKS 88
Query: 328 LVYYHDDRPRWQEVFKV 344
++YY +PRW E KV
Sbjct: 89 VIYYQVKQPRWFETVKV 105
>AB018326-1|BAA34503.2| 899|Homo sapiens KIAA0783 protein protein.
Length = 899
Score = 33.9 bits (74), Expect = 2.2
Identities = 19/52 (36%), Positives = 28/52 (53%)
Query: 161 VSMSTSAGAMRRPFGVACADIKRHLTSDNPDKHIQVPFYAYEKENLDALLKK 212
V +S AG R F V CA + L+ ++ I PF+AY K++ D L +K
Sbjct: 465 VCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRK 516
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.136 0.407
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,400,643
Number of Sequences: 224733
Number of extensions: 3880146
Number of successful extensions: 7501
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 7299
Number of HSP's gapped (non-prelim): 40
length of query: 767
length of database: 73,234,838
effective HSP length: 96
effective length of query: 671
effective length of database: 51,660,470
effective search space: 34664175370
effective search space used: 34664175370
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)
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