Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002318-TA|BGIBMGA002318-PA|IPR001478|PDZ/DHR/GLGF,
IPR001940|Peptidase S1C, HrtA/DegP2/Q/S, IPR002731|ATPase,
BadF/BadG/BcrA/BcrD type, IPR001254|Peptidase S1 and S6,
chymotrypsin/Hap, IPR009003|Peptidase, trypsin-like serine and
cysteine
(579 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC000096-1|AAH00096.1| 458|Homo sapiens HtrA serine peptidase 2... 318 3e-86
AF141305-1|AAF66596.1| 458|Homo sapiens serine protease Htra2 p... 318 3e-86
AF020760-1|AAB94569.2| 458|Homo sapiens serine protease protein. 318 3e-86
BC035717-1|AAH35717.1| 453|Homo sapiens HtrA serine peptidase 3... 285 3e-76
BC034390-1|AAH34390.1| 453|Homo sapiens HtrA serine peptidase 3... 285 3e-76
AY280665-1|AAP42282.1| 453|Homo sapiens pregnancy-related serin... 285 3e-76
AY040094-1|AAK71475.2| 453|Homo sapiens serine protease HTRA3 p... 285 3e-76
Y07921-1|CAA69226.1| 480|Homo sapiens novel serine protease, PR... 284 5e-76
D87258-1|BAA13322.1| 480|Homo sapiens serin protease with IGF-b... 284 5e-76
BC011352-1|AAH11352.1| 445|Homo sapiens HTRA1 protein protein. 284 5e-76
AF157623-1|AAD41525.1| 480|Homo sapiens HTRA serine protease pr... 284 5e-76
AF097709-1|AAC97211.1| 337|Homo sapiens serine protease protein. 282 2e-75
AK075205-1|BAC11470.1| 476|Homo sapiens protein ( Homo sapiens ... 279 2e-74
BC057765-1|AAH57765.1| 476|Homo sapiens HtrA serine peptidase 4... 278 4e-74
AF141306-1|AAF66597.1| 423|Homo sapiens serine protease HtrA2-p... 227 6e-59
AY280666-1|AAP42283.1| 357|Homo sapiens pregnancy-related serin... 215 4e-55
AF141307-1|AAF66598.1| 323|Homo sapiens serine protease HtrA2-p... 184 1e-45
CR457271-1|CAG33552.1| 344|Homo sapiens NAGK protein. 125 4e-28
BC005371-1|AAH05371.1| 344|Homo sapiens N-acetylglucosamine kin... 125 4e-28
BC001029-1|AAH01029.1| 344|Homo sapiens N-acetylglucosamine kin... 125 4e-28
AK001812-1|BAA91923.1| 344|Homo sapiens protein ( Homo sapiens ... 125 4e-28
AJ242910-1|CAB61848.1| 344|Homo sapiens N-Acetylglucosamine kin... 125 4e-28
AC007881-1|AAY14748.1| 344|Homo sapiens unknown protein. 125 4e-28
AK222645-1|BAD96365.1| 344|Homo sapiens N-Acetylglucosamine kin... 125 5e-28
AF184911-1|AAG13126.1| 361|Homo sapiens serine protease protein. 89 5e-17
AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protei... 44 0.002
AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein. 44 0.002
L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula oc... 43 0.003
DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein ... 43 0.003
BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein ... 43 0.003
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 40 0.018
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 40 0.018
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 40 0.018
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 40 0.018
AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated ... 40 0.018
AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein. 40 0.018
AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein. 40 0.018
L27476-1|AAA61300.1| 1116|Homo sapiens X104 protein. 38 0.074
BC027985-1|AAH27985.1| 1063|Homo sapiens MAST1 protein protein. 38 0.074
BC027592-1|AAH27592.1| 1190|Homo sapiens tight junction protein ... 38 0.074
AL358113-3|CAH70868.1| 1190|Homo sapiens tight junction protein ... 38 0.074
AL358113-2|CAM13389.1| 1043|Homo sapiens tight junction protein ... 38 0.074
AL358113-1|CAH70867.1| 993|Homo sapiens tight junction protein ... 38 0.074
AF489824-1|AAM28524.1| 993|Homo sapiens tight junction protein ... 38 0.074
AF177533-4|AAD56219.2| 1020|Homo sapiens tight junction protein ... 38 0.074
AF177533-3|AAC02527.2| 1167|Homo sapiens tight junction protein ... 38 0.074
AF177533-2|AAD56218.2| 1043|Homo sapiens tight junction protein ... 38 0.074
AF177533-1|AAD20387.2| 1190|Homo sapiens tight junction protein ... 38 0.074
AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human seri... 38 0.074
AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein. 38 0.074
BC108907-1|AAI08908.2| 917|Homo sapiens TJP3 protein protein. 36 0.30
BC108906-1|AAI08907.1| 938|Homo sapiens TJP3 protein protein. 36 0.30
AC005954-1|AAC72274.1| 952|Homo sapiens ZO-3 [Homo sapiens] pro... 36 0.30
BC118915-1|AAI18916.1| 1406|Homo sapiens ARHGAP21 protein protein. 36 0.39
AL392104-2|CAI40177.1| 189|Homo sapiens Rho GTPase activating p... 36 0.39
AL392104-1|CAI40176.1| 1957|Homo sapiens Rho GTPase activating p... 36 0.39
AL355979-2|CAI14324.1| 189|Homo sapiens Rho GTPase activating p... 36 0.39
AL355979-1|CAI14323.1| 1957|Homo sapiens Rho GTPase activating p... 36 0.39
AF480466-1|AAM22955.1| 1957|Homo sapiens Rho-GTPase activating p... 36 0.39
AB037845-1|BAA92662.2| 1944|Homo sapiens KIAA1424 protein protein. 36 0.39
AY190519-1|AAO38848.1| 1692|Homo sapiens Rab3A-interacting molec... 36 0.52
AL590011-1|CAI16961.1| 1039|Homo sapiens regulating synaptic mem... 36 0.52
AL445256-1|CAI39598.1| 1039|Homo sapiens regulating synaptic mem... 36 0.52
AL390056-1|CAI21554.1| 1039|Homo sapiens regulating synaptic mem... 36 0.52
AL034373-1|CAI20558.1| 1039|Homo sapiens regulating synaptic mem... 36 0.52
AC007192-1|AAD22670.1| 681|Homo sapiens KIAA0561 protein [AA 62... 36 0.52
AB051866-1|BAB87242.1| 1470|Homo sapiens RIM long form protein. 36 0.52
AB045726-1|BAB87121.1| 1028|Homo sapiens RIM short form protein. 36 0.52
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 36 0.52
AB002338-1|BAA20798.1| 1053|Homo sapiens KIAA0340 protein. 36 0.52
BC037988-1|AAH37988.1| 904|Homo sapiens MICAL-like 2 protein. 35 0.69
AK074068-1|BAB84894.1| 585|Homo sapiens FLJ00139 protein protein. 35 0.69
M59941-1|AAA18171.1| 897|Homo sapiens GM-CSF receptor beta chai... 34 1.2
L06633-1|AAA16575.1| 324|Homo sapiens transcription factor prot... 34 1.2
CR456428-1|CAG30314.1| 903|Homo sapiens CSF2RB protein. 34 1.2
BC070085-1|AAH70085.1| 889|Homo sapiens CSF2RB protein protein. 34 1.2
BC036449-1|AAH36449.1| 359|Homo sapiens pleckstrin homology, Se... 34 1.2
AL133392-1|CAI23586.1| 897|Homo sapiens colony stimulating fact... 34 1.2
AL008637-2|CAI17999.1| 897|Homo sapiens colony stimulating fact... 34 1.2
AF068836-1|AAC19129.1| 359|Homo sapiens cytohesin binding prote... 34 1.2
AC019201-1|AAY14898.1| 359|Homo sapiens unknown protein. 34 1.2
AK027292-1|BAB55020.1| 548|Homo sapiens protein ( Homo sapiens ... 33 2.1
BC104036-1|AAI04037.1| 428|Homo sapiens ARL13B protein protein. 33 2.8
BC104035-1|AAI04036.1| 428|Homo sapiens ARL13B protein protein. 33 2.8
BC094725-1|AAH94725.1| 321|Homo sapiens ADP-ribosylation factor... 33 2.8
BC029042-1|AAH29042.1| 491|Homo sapiens PDZ domain containing 3... 33 2.8
AY047359-1|AAL10686.1| 505|Homo sapiens intestinal and kidney e... 33 2.8
AB094096-1|BAC76050.1| 571|Homo sapiens DLNB27 protein. 33 2.8
CR456437-1|CAG30323.1| 863|Homo sapiens dJ1014D13.2 protein. 33 3.7
BC025767-1|AAH25767.1| 670|Homo sapiens rhophilin, Rho GTPase b... 33 3.7
AY082588-1|AAL89809.1| 695|Homo sapiens rhophilin-1 protein. 33 3.7
AL022311-1|CAI18864.1| 863|Homo sapiens protein ( Human DNA seq... 33 3.7
AJ496196-1|CAD42713.1| 863|Homo sapiens molecule interacting wi... 33 3.7
X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphat... 32 4.8
U12128-1|AAB60339.1| 2490|Homo sapiens protein tyrosine phosphat... 32 4.8
L34583-1|AAC41755.1| 610|Homo sapiens tyrosine phosphatase prot... 32 4.8
D21211-1|BAA04752.1| 2294|Homo sapiens protein tyrosine phosphat... 32 4.8
D21210-1|BAA04751.1| 2466|Homo sapiens protein tyrosine phosphat... 32 4.8
D21209-1|BAA04750.1| 2485|Homo sapiens protein tyrosine phosphat... 32 4.8
BC039610-1|AAH39610.1| 604|Homo sapiens PTPN13 protein protein. 32 4.8
BC016057-1|AAH16057.1| 533|Homo sapiens USH1C protein protein. 32 4.8
BC006518-1|AAH06518.1| 519|Homo sapiens PDZ domain containing 1... 32 4.8
BC006496-1|AAH06496.1| 519|Homo sapiens PDZ domain containing 1... 32 4.8
AL391240-1|CAM28242.1| 2106|Homo sapiens novel protein protein. 32 4.8
AL390725-5|CAI13716.1| 519|Homo sapiens PDZ domain containing 1... 32 4.8
AL031433-2|CAI19661.2| 2106|Homo sapiens novel protein protein. 32 4.8
AL031003-5|CAM28244.1| 2106|Homo sapiens novel protein protein. 32 4.8
AF039700-1|AAC18049.1| 652|Homo sapiens antigen NY-CO-38 protein. 32 4.8
AF039699-1|AAC18048.1| 403|Homo sapiens antigen NY-CO-37 protein. 32 4.8
AF012281-1|AAC12264.1| 519|Homo sapiens PDZ domain containing-p... 32 4.8
AC105413-1|AAY40972.1| 1305|Homo sapiens unknown protein. 32 4.8
AB208904-1|BAD92141.1| 2434|Homo sapiens protein tyrosine phosph... 32 4.8
AB018687-1|BAA81740.1| 552|Homo sapiens autoimmune enteropathy-... 32 4.8
AB006955-1|BAA81739.1| 521|Homo sapiens AIE-75 protein. 32 4.8
BC023980-1|AAH23980.1| 124|Homo sapiens Tax1 (human T-cell leuk... 32 6.4
AF277318-1|AAK69111.1| 124|Homo sapiens tax-interacting protein... 32 6.4
AF234997-1|AAG44368.1| 124|Homo sapiens glutaminase-interacting... 32 6.4
AF168787-3|AAF43104.1| 116|Homo sapiens TIP1 protein. 32 6.4
AF028823-1|AAB84248.2| 124|Homo sapiens Tax interaction protein... 32 6.4
U61843-1|AAC61295.1| 674|Homo sapiens discs large protein P-dlg... 31 8.4
BC073996-1|AAH73996.1| 845|Homo sapiens DLG5 protein protein. 31 8.4
AL450306-3|CAI17324.2| 1919|Homo sapiens discs, large homolog 5 ... 31 8.4
AL450306-2|CAI17323.1| 880|Homo sapiens discs, large homolog 5 ... 31 8.4
AL391421-2|CAI12104.2| 1919|Homo sapiens discs, large homolog 5 ... 31 8.4
AL391421-1|CAI12103.1| 880|Homo sapiens discs, large homolog 5 ... 31 8.4
AF352034-1|AAL83938.1| 1809|Homo sapiens DLG5 protein. 31 8.4
AF352033-1|AAL83937.1| 1809|Homo sapiens DLG5 protein. 31 8.4
AB091676-1|BAC65420.1| 1764|Homo sapiens discs large protein lp-... 31 8.4
AB011155-1|BAA25509.2| 1952|Homo sapiens KIAA0583 protein protein. 31 8.4
>BC000096-1|AAH00096.1| 458|Homo sapiens HtrA serine peptidase 2
protein.
Length = 458
Score = 318 bits (781), Expect = 3e-86
Identities = 164/320 (51%), Positives = 219/320 (68%), Gaps = 13/320 (4%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
++ V+VRL G T+EA++ D +D+ATLRI K LPT+ LG SAD++ GE+VV
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVV 258
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGEAI 443
A+GSP L NT+T+G+VSS QR +LGL N+ YIQTDA I FGNSGGPLVNLDGE I
Sbjct: 259 AMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVI 318
Query: 444 GINSMKVTYGISFAIPIDYVKEFL--AKHKTKSPQVS---KRYLGITMLSLTPSILMELK 498
G+N+MKVT GISFAIP D ++EFL + K S +S +RY+G+ ML+L+PSIL EL+
Sbjct: 319 GVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQ 378
Query: 499 MRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTTGS 558
+R P P D+QHG+L+ KVI+GSPA GL+PGD+++ I + V N D+Y + T
Sbjct: 379 LREPSFP-DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVR-TQSQ 436
Query: 559 LKIDAVRGRQQINLTIVPEL 578
L + RGR+ + L + PE+
Sbjct: 437 LAVQIRRGRETLTLYVTPEV 456
>AF141305-1|AAF66596.1| 458|Homo sapiens serine protease Htra2
protein.
Length = 458
Score = 318 bits (781), Expect = 3e-86
Identities = 164/320 (51%), Positives = 219/320 (68%), Gaps = 13/320 (4%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
++ V+VRL G T+EA++ D +D+ATLRI K LPT+ LG SAD++ GE+VV
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVV 258
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGEAI 443
A+GSP L NT+T+G+VSS QR +LGL N+ YIQTDA I FGNSGGPLVNLDGE I
Sbjct: 259 AMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVI 318
Query: 444 GINSMKVTYGISFAIPIDYVKEFL--AKHKTKSPQVS---KRYLGITMLSLTPSILMELK 498
G+N+MKVT GISFAIP D ++EFL + K S +S +RY+G+ ML+L+PSIL EL+
Sbjct: 319 GVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQ 378
Query: 499 MRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTTGS 558
+R P P D+QHG+L+ KVI+GSPA GL+PGD+++ I + V N D+Y + T
Sbjct: 379 LREPSFP-DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVR-TQSQ 436
Query: 559 LKIDAVRGRQQINLTIVPEL 578
L + RGR+ + L + PE+
Sbjct: 437 LAVQIRRGRETLTLYVTPEV 456
>AF020760-1|AAB94569.2| 458|Homo sapiens serine protease protein.
Length = 458
Score = 318 bits (781), Expect = 3e-86
Identities = 164/320 (51%), Positives = 219/320 (68%), Gaps = 13/320 (4%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
++ V+VRL G T+EA++ D +D+ATLRI K LPT+ LG SAD++ GE+VV
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVV 258
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGEAI 443
A+GSP L NT+T+G+VSS QR +LGL N+ YIQTDA I FGNSGGPLVNLDGE I
Sbjct: 259 AMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVI 318
Query: 444 GINSMKVTYGISFAIPIDYVKEFL--AKHKTKSPQVS---KRYLGITMLSLTPSILMELK 498
G+N+MKVT GISFAIP D ++EFL + K S +S +RY+G+ ML+L+PSIL EL+
Sbjct: 319 GVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQ 378
Query: 499 MRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTTGS 558
+R P P D+QHG+L+ KVI+GSPA GL+PGD+++ I + V N D+Y + T
Sbjct: 379 LREPSFP-DVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVR-TQSQ 436
Query: 559 LKIDAVRGRQQINLTIVPEL 578
L + RGR+ + L + PE+
Sbjct: 437 LAVQIRRGRETLTLYVTPEV 456
>BC035717-1|AAH35717.1| 453|Homo sapiens HtrA serine peptidase 3
protein.
Length = 453
Score = 285 bits (699), Expect = 3e-76
Identities = 155/327 (47%), Positives = 218/327 (66%), Gaps = 11/327 (3%)
Query: 258 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 317
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 318 LTNAHVVVNKPNAI----VKVRLTDGSTHEALIEHYDLQSDLATLRI-PVKGLPTMKLGT 372
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT++I P K LP + LG
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGH 246
Query: 373 SADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSG 432
SADL+PGE+VVAIGSP L NTVT G+VS+ QR G ELGL+D ++ YIQTDA I +GNSG
Sbjct: 247 SADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSG 306
Query: 433 GPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKS-PQVSKRYLGITMLSLTP 491
GPLVNLDGE IGIN++KVT GISFAIP D + FL + + K KR++GI M ++TP
Sbjct: 307 GPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITP 366
Query: 492 SILMELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNI 551
S++ ELK NP+ P ++ GI V +V SP+ GG+Q GDI+VK+NG+P+ +++++
Sbjct: 367 SLVDELKASNPDFP-EVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEA 425
Query: 552 LESTTGSLKIDAVRGRQQINLTIVPEL 578
+ T L ++ RG + +I PE+
Sbjct: 426 V-LTESPLLLEVRRGNDDLLFSIAPEV 451
>BC034390-1|AAH34390.1| 453|Homo sapiens HtrA serine peptidase 3
protein.
Length = 453
Score = 285 bits (699), Expect = 3e-76
Identities = 155/327 (47%), Positives = 218/327 (66%), Gaps = 11/327 (3%)
Query: 258 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 317
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 318 LTNAHVVVNKPNAI----VKVRLTDGSTHEALIEHYDLQSDLATLRI-PVKGLPTMKLGT 372
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT++I P K LP + LG
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGH 246
Query: 373 SADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSG 432
SADL+PGE+VVAIGSP L NTVT G+VS+ QR G ELGL+D ++ YIQTDA I +GNSG
Sbjct: 247 SADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSG 306
Query: 433 GPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKS-PQVSKRYLGITMLSLTP 491
GPLVNLDGE IGIN++KVT GISFAIP D + FL + + K KR++GI M ++TP
Sbjct: 307 GPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITP 366
Query: 492 SILMELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNI 551
S++ ELK NP+ P ++ GI V +V SP+ GG+Q GDI+VK+NG+P+ +++++
Sbjct: 367 SLVDELKASNPDFP-EVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEA 425
Query: 552 LESTTGSLKIDAVRGRQQINLTIVPEL 578
+ T L ++ RG + +I PE+
Sbjct: 426 V-LTESPLLLEVRRGNDDLLFSIAPEV 451
>AY280665-1|AAP42282.1| 453|Homo sapiens pregnancy-related serine
protease HTRA3 protein.
Length = 453
Score = 285 bits (699), Expect = 3e-76
Identities = 155/327 (47%), Positives = 218/327 (66%), Gaps = 11/327 (3%)
Query: 258 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 317
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 318 LTNAHVVVNKPNAI----VKVRLTDGSTHEALIEHYDLQSDLATLRI-PVKGLPTMKLGT 372
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT++I P K LP + LG
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGH 246
Query: 373 SADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSG 432
SADL+PGE+VVAIGSP L NTVT G+VS+ QR G ELGL+D ++ YIQTDA I +GNSG
Sbjct: 247 SADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSG 306
Query: 433 GPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKS-PQVSKRYLGITMLSLTP 491
GPLVNLDGE IGIN++KVT GISFAIP D + FL + + K KR++GI M ++TP
Sbjct: 307 GPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITP 366
Query: 492 SILMELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNI 551
S++ ELK NP+ P ++ GI V +V SP+ GG+Q GDI+VK+NG+P+ +++++
Sbjct: 367 SLVDELKASNPDFP-EVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEA 425
Query: 552 LESTTGSLKIDAVRGRQQINLTIVPEL 578
+ T L ++ RG + +I PE+
Sbjct: 426 V-LTESPLLLEVRRGNDDLLFSIAPEV 451
>AY040094-1|AAK71475.2| 453|Homo sapiens serine protease HTRA3
protein.
Length = 453
Score = 285 bits (699), Expect = 3e-76
Identities = 155/327 (47%), Positives = 218/327 (66%), Gaps = 11/327 (3%)
Query: 258 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 317
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 318 LTNAHVVVNKPNAI----VKVRLTDGSTHEALIEHYDLQSDLATLRI-PVKGLPTMKLGT 372
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT++I P K LP + LG
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGH 246
Query: 373 SADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSG 432
SADL+PGE+VVAIGSP L NTVT G+VS+ QR G ELGL+D ++ YIQTDA I +GNSG
Sbjct: 247 SADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSG 306
Query: 433 GPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKS-PQVSKRYLGITMLSLTP 491
GPLVNLDGE IGIN++KVT GISFAIP D + FL + + K KR++GI M ++TP
Sbjct: 307 GPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITP 366
Query: 492 SILMELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNI 551
S++ ELK NP+ P ++ GI V +V SP+ GG+Q GDI+VK+NG+P+ +++++
Sbjct: 367 SLVDELKASNPDFP-EVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEA 425
Query: 552 LESTTGSLKIDAVRGRQQINLTIVPEL 578
+ T L ++ RG + +I PE+
Sbjct: 426 V-LTESPLLLEVRRGNDDLLFSIAPEV 451
>Y07921-1|CAA69226.1| 480|Homo sapiens novel serine protease,
PRSS11 protein.
Length = 480
Score = 284 bits (697), Expect = 5e-76
Identities = 151/323 (46%), Positives = 220/323 (68%), Gaps = 12/323 (3%)
Query: 260 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 319
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 320 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKP 378
NAHVV NK VKV L +G+T+EA I+ D ++D+A ++I +G LP + LG S++L+P
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP 275
Query: 379 GEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL 438
GE+VVAIGSP L NTVT G+VS+TQR G ELGL++ ++ YIQTDA I +GNSGGPLVNL
Sbjct: 276 GEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNL 335
Query: 439 DGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKSPQ----VSKRYLGITMLSLTPSIL 494
DGE IGIN++KVT GISFAIP D +K+FL + + + K+Y+GI M+SLT S
Sbjct: 336 DGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKA 395
Query: 495 MELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILES 554
ELK R+ + P D+ G + +VI +PA GGL+ D+++ ING+ V + D+ ++++
Sbjct: 396 KELKDRHRDFP-DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 454
Query: 555 TTGSLKIDAVRGRQQINLTIVPE 577
+ +L + RG + I +T++PE
Sbjct: 455 ES-TLNMVVRRGNEDIMITVIPE 476
>D87258-1|BAA13322.1| 480|Homo sapiens serin protease with
IGF-binding motif protein.
Length = 480
Score = 284 bits (697), Expect = 5e-76
Identities = 151/323 (46%), Positives = 220/323 (68%), Gaps = 12/323 (3%)
Query: 260 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 319
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 320 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKP 378
NAHVV NK VKV L +G+T+EA I+ D ++D+A ++I +G LP + LG S++L+P
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP 275
Query: 379 GEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL 438
GE+VVAIGSP L NTVT G+VS+TQR G ELGL++ ++ YIQTDA I +GNSGGPLVNL
Sbjct: 276 GEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNL 335
Query: 439 DGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKSPQ----VSKRYLGITMLSLTPSIL 494
DGE IGIN++KVT GISFAIP D +K+FL + + + K+Y+GI M+SLT S
Sbjct: 336 DGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKA 395
Query: 495 MELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILES 554
ELK R+ + P D+ G + +VI +PA GGL+ D+++ ING+ V + D+ ++++
Sbjct: 396 KELKDRHRDFP-DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 454
Query: 555 TTGSLKIDAVRGRQQINLTIVPE 577
+ +L + RG + I +T++PE
Sbjct: 455 ES-TLNMVVRRGNEDIMITVIPE 476
>BC011352-1|AAH11352.1| 445|Homo sapiens HTRA1 protein protein.
Length = 445
Score = 284 bits (697), Expect = 5e-76
Identities = 151/323 (46%), Positives = 220/323 (68%), Gaps = 12/323 (3%)
Query: 260 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 319
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 126 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 182
Query: 320 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKP 378
NAHVV NK VKV L +G+T+EA I+ D ++D+A ++I +G LP + LG S++L+P
Sbjct: 183 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP 240
Query: 379 GEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL 438
GE+VVAIGSP L NTVT G+VS+TQR G ELGL++ ++ YIQTDA I +GNSGGPLVNL
Sbjct: 241 GEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNL 300
Query: 439 DGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKSPQ----VSKRYLGITMLSLTPSIL 494
DGE IGIN++KVT GISFAIP D +K+FL + + + K+Y+GI M+SLT S
Sbjct: 301 DGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKA 360
Query: 495 MELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILES 554
ELK R+ + P D+ G + +VI +PA GGL+ D+++ ING+ V + D+ ++++
Sbjct: 361 KELKDRHRDFP-DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 419
Query: 555 TTGSLKIDAVRGRQQINLTIVPE 577
+ +L + RG + I +T++PE
Sbjct: 420 ES-TLNMVVRRGNEDIMITVIPE 441
>AF157623-1|AAD41525.1| 480|Homo sapiens HTRA serine protease
protein.
Length = 480
Score = 284 bits (697), Expect = 5e-76
Identities = 151/323 (46%), Positives = 220/323 (68%), Gaps = 12/323 (3%)
Query: 260 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 319
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 320 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKP 378
NAHVV NK VKV L +G+T+EA I+ D ++D+A ++I +G LP + LG S++L+P
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP 275
Query: 379 GEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL 438
GE+VVAIGSP L NTVT G+VS+TQR G ELGL++ ++ YIQTDA I +GNSGGPLVNL
Sbjct: 276 GEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNL 335
Query: 439 DGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKSPQ----VSKRYLGITMLSLTPSIL 494
DGE IGIN++KVT GISFAIP D +K+FL + + + K+Y+GI M+SLT S
Sbjct: 336 DGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKA 395
Query: 495 MELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILES 554
ELK R+ + P D+ G + +VI +PA GGL+ D+++ ING+ V + D+ ++++
Sbjct: 396 KELKDRHRDFP-DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 454
Query: 555 TTGSLKIDAVRGRQQINLTIVPE 577
+ +L + RG + I +T++PE
Sbjct: 455 ES-TLNMVVRRGNEDIMITVIPE 476
>AF097709-1|AAC97211.1| 337|Homo sapiens serine protease protein.
Length = 337
Score = 282 bits (692), Expect = 2e-75
Identities = 150/323 (46%), Positives = 219/323 (67%), Gaps = 12/323 (3%)
Query: 260 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 319
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 18 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 74
Query: 320 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKP 378
NAHVV NK VKV L +G+T+EA I+ D ++D+A ++I +G LP + LG S++L+P
Sbjct: 75 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRP 132
Query: 379 GEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL 438
GE+VVAIGSP L NTVT G+VS+TQR G ELGL++ ++ YIQTDA +GNSGGPLVNL
Sbjct: 133 GEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAITNYGNSGGPLVNL 192
Query: 439 DGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTKSPQ----VSKRYLGITMLSLTPSIL 494
DGE IGIN++KVT GISFAIP D +K+FL + + + K+Y+GI M+SLT S
Sbjct: 193 DGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKA 252
Query: 495 MELKMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILES 554
ELK R+ + P D+ G + +VI +PA GGL+ D+++ ING+ V + D+ ++++
Sbjct: 253 KELKDRHRDFP-DVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKR 311
Query: 555 TTGSLKIDAVRGRQQINLTIVPE 577
+ +L + RG + I +T++PE
Sbjct: 312 ES-TLNMVVRRGNEDIMITVIPE 333
>AK075205-1|BAC11470.1| 476|Homo sapiens protein ( Homo sapiens
cDNA FLJ90724 fis, clone PLACE1009279, highly similar to
Probable serine protease HTRA4 precursor (EC3.4.21.-).
).
Length = 476
Score = 279 bits (684), Expect = 2e-74
Identities = 148/318 (46%), Positives = 213/318 (66%), Gaps = 13/318 (4%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R YNFIA ++++ GR + + + + +GSGFI+ EDGLI+TNAHVV
Sbjct: 164 RRNYNFIAAVVEKVAPSVVHVQLW-GRLLHG--SRLVPVYSGSGFIVSEDGLIITNAHVV 220
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
N+ ++V L +G+ +EA+++ DL+ DLA ++I LP + LG S+DL+ GE+VV
Sbjct: 221 RNQQ--WIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVV 278
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGEAI 443
A+GSP L NT TAG+VS+ QR G ELG++D ++ Y+Q DA I +GNSGGPLVNLDG+ I
Sbjct: 279 ALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVI 338
Query: 444 GINSMKVTYGISFAIPIDYVKEFLA---KHKTKSPQVS-KRYLGITMLSLTPSILMELKM 499
G+NS++VT GISFAIP D V++FLA +H+ K S K+YLG+ MLSLT + ELKM
Sbjct: 339 GVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKM 398
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTTGSL 559
P+ P D+ G+ V KV+ G+ A + GL+ D++V INGKP+ TTD+ L+S SL
Sbjct: 399 HYPDFP-DVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDS--DSL 455
Query: 560 KIDAVRGRQQINLTIVPE 577
+ +RG+ + LT++PE
Sbjct: 456 SMAVLRGKDNLLLTVIPE 473
>BC057765-1|AAH57765.1| 476|Homo sapiens HtrA serine peptidase 4
protein.
Length = 476
Score = 278 bits (681), Expect = 4e-74
Identities = 148/318 (46%), Positives = 212/318 (66%), Gaps = 13/318 (4%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R YNFIA ++++ GR + + + + +GSGFI+ EDGLI+TNAHVV
Sbjct: 164 RRNYNFIAAVVEKVAPSVVHVQLW-GRLLHG--SRLVPVYSGSGFIVSEDGLIITNAHVV 220
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
N+ ++V L +G+ +EA+++ DL+ DLA ++I LP + LG S+DL+ GE+VV
Sbjct: 221 RNQQ--WIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVV 278
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGEAI 443
A+GSP L NT TAG+VS+ QR G ELG++D ++ Y+Q DA I +GNSGGPLVNLDG+ I
Sbjct: 279 ALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVI 338
Query: 444 GINSMKVTYGISFAIPIDYVKEFLA---KHKTKSPQVS-KRYLGITMLSLTPSILMELKM 499
G+NS++VT GISFAIP D V++FLA +H+ K S K+YLG+ MLSLT + ELKM
Sbjct: 339 GVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKM 398
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTTGSL 559
P+ P D+ G+ V KV G+ A + GL+ D++V INGKP+ TTD+ L+S SL
Sbjct: 399 HYPDFP-DVSSGVYVCKVFEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDS--DSL 455
Query: 560 KIDAVRGRQQINLTIVPE 577
+ +RG+ + LT++PE
Sbjct: 456 SMAVLRGKDNLLLTVIPE 473
>AF141306-1|AAF66597.1| 423|Homo sapiens serine protease HtrA2-p7
protein.
Length = 423
Score = 227 bits (556), Expect = 6e-59
Identities = 126/243 (51%), Positives = 163/243 (67%), Gaps = 21/243 (8%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 131 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 187
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
++ V+VRL G T+EA++ D +D+ATLRI K LPT+ LG SAD++ GE+VV
Sbjct: 188 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVV 245
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNL----- 438
A+GSP L NT+T+G+VSS QR +LGL N+ YIQTDA I FGNSGGPLVNL
Sbjct: 246 AMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLARELG 305
Query: 439 -----DGEAIGINSMKVTYGISFAIPIDYVKEFL--AKHKTKSPQVS---KRYLGITMLS 488
DGE IG+N+MKVT GISFAIP D ++EFL + K S +S +RY+G+ ML+
Sbjct: 306 AVSLQDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLT 365
Query: 489 LTP 491
L+P
Sbjct: 366 LSP 368
>AY280666-1|AAP42283.1| 357|Homo sapiens pregnancy-related serine
protease HTRA3 protein.
Length = 357
Score = 215 bits (525), Expect = 4e-55
Identities = 117/221 (52%), Positives = 153/221 (69%), Gaps = 8/221 (3%)
Query: 258 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 317
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 318 LTNAHVVVNKPNAI----VKVRLTDGSTHEALIEHYDLQSDLATLRI-PVKGLPTMKLGT 372
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT++I P K LP + LG
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGH 246
Query: 373 SADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSG 432
SADL+PGE+VVAIGSP L NTVT G+VS+ QR G ELGL+D ++ YIQTDA I +GNSG
Sbjct: 247 SADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSG 306
Query: 433 GPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFLAKHKTK 473
GPLVNLDGE IGIN++KVT GISFAIP D + FL + + K
Sbjct: 307 GPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDK 347
>AF141307-1|AAF66598.1| 323|Homo sapiens serine protease HtrA2-p4
protein.
Length = 323
Score = 184 bits (447), Expect = 1e-45
Identities = 96/178 (53%), Positives = 122/178 (68%), Gaps = 6/178 (3%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 90 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 146
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVKG-LPTMKLGTSADLKPGEWVV 383
++ V+VRL G T+EA++ D +D+ATLRI K LPT+ LG SAD++ GE+VV
Sbjct: 147 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVV 204
Query: 384 AIGSPLDLSNTVTAGVVSSTQRAGSELGLQDRNIVYIQTDAPITFGNSGGPLVNLDGE 441
A+GSP L NT+T+G+VSS QR +LGL N+ YIQTDA I FGNSGGPLVNL E
Sbjct: 205 AMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLVSE 262
>CR457271-1|CAG33552.1| 344|Homo sapiens NAGK protein.
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>BC005371-1|AAH05371.1| 344|Homo sapiens N-acetylglucosamine kinase
protein.
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>BC001029-1|AAH01029.1| 344|Homo sapiens N-acetylglucosamine kinase
protein.
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>AK001812-1|BAA91923.1| 344|Homo sapiens protein ( Homo sapiens
cDNA FLJ10950 fis, clone PLACE1000185. ).
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLVLTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIRHLLPMDYSANAIAFYSY 341
>AJ242910-1|CAB61848.1| 344|Homo sapiens N-Acetylglucosamine kinase
protein.
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 IVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>AC007881-1|AAY14748.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 125 bits (302), Expect = 4e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKCRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>AK222645-1|BAD96365.1| 344|Homo sapiens N-Acetylglucosamine kinase
variant protein.
Length = 344
Score = 125 bits (301), Expect = 5e-28
Identities = 76/221 (34%), Positives = 106/221 (47%), Gaps = 12/221 (5%)
Query: 1 MVSSSGTGSNALLRTSDGEQHNCXXXXXXXXXXXXAYWIAHKAVKSVIDDVDGLRISPYP 60
+V SGTGSN L DG + C AYWIAH+AVK V D +D L +P+
Sbjct: 121 VVLISGTGSNCRLINPDGSESGCGGWGHMMGDEGSAYWIAHQAVKIVFDSIDNLEAAPHD 180
Query: 61 THNVWEVIREHFDADTRADLLPHAYKNFNKSQFAGLTVKLSALAYKGDELSRHIFXXXXX 120
V + + +F R +L H Y++F+K +FAG K++ A +GD LSR+IF
Sbjct: 181 IGYVKQAMFHYFQVPDRLGILTHLYRDFDKYRFAGFCRKIAEGAQQGDPLSRYIFRKAGE 240
Query: 121 XXXXXXXXXXXXXTAK------RLRVVCVGSVWNSWDVLKPGML------NELNAKKVKC 168
L ++CVGSVW SW++LK G L E+ A+
Sbjct: 241 MLGRHIVAVLPEIDPVLFQGKIGLPILCVGSVWKSWELLKEGFLLALTQGREIQAQNFFS 300
Query: 169 ELELVRLKVSSAMGAAWLAANKINYDLPRDDEAFCQVFHKY 209
L++L+ SSA+G A L A I + LP D A F+ Y
Sbjct: 301 SFTLMKLRHSSALGGASLGARHIGHLLPMDYSANAIAFYSY 341
>AF184911-1|AAG13126.1| 361|Homo sapiens serine protease protein.
Length = 361
Score = 88.6 bits (210), Expect = 5e-17
Identities = 47/99 (47%), Positives = 63/99 (63%), Gaps = 5/99 (5%)
Query: 265 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 324
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 325 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATLRIPVK 363
++ V+VRL G T+EA++ D +D+ATLRI K
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATLRIQTK 237
Score = 84.2 bits (199), Expect = 1e-15
Identities = 42/69 (60%), Positives = 53/69 (76%), Gaps = 5/69 (7%)
Query: 428 FGNSGGPLVNLDGEAIGINSMKVTYGISFAIPIDYVKEFL--AKHKTKSPQVS---KRYL 482
FGNSGGPLVNLDGE IG+N+MKVT GISFAIP D ++EFL + K S +S +RY+
Sbjct: 238 FGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYI 297
Query: 483 GITMLSLTP 491
G+ ML+L+P
Sbjct: 298 GVMMLTLSP 306
Score = 41.9 bits (94), Expect = 0.006
Identities = 18/52 (34%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 527 GLQPGDIVVKINGKPVHNTTDIYNILESTTGSLKIDAVRGRQQINLTIVPEL 578
GL+PGD+++ I + V N D+Y + T L + RGR+ + L + PE+
Sbjct: 309 GLRPGDVILAIGEQMVQNAEDVYEAVR-TQSQLAVQIRRGRETLTLYVTPEV 359
>AY830839-1|AAW52510.1| 2434|Homo sapiens serine/threonine protein
kinase protein.
Length = 2434
Score = 43.6 bits (98), Expect = 0.002
Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKI 561
+VW V GSPA GL+ GD++ ING+PVH T++ +L + + I
Sbjct: 984 IVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSI 1034
>AB002301-1|BAA20762.1| 2137|Homo sapiens KIAA0303 protein.
Length = 2137
Score = 43.6 bits (98), Expect = 0.002
Identities = 20/51 (39%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKI 561
+VW V GSPA GL+ GD++ ING+PVH T++ +L + + I
Sbjct: 687 IVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSI 737
>L14837-1|AAA02891.1| 1736|Homo sapiens tight junction (zonula
occludens) protein ZO-1 protein.
Length = 1736
Score = 42.7 bits (96), Expect = 0.003
Identities = 30/114 (26%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 468 AKHKTKSPQVSKRYLGITMLSLTPSILMELKMRNPEMPTDIQHGILVWKVIIGS-PAFNG 526
++ ++ SP+ +R + + + + + +N E + I V ++ S A +G
Sbjct: 150 SRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDG 209
Query: 527 GLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPEL 578
+Q GD+V+KING N TD ++E + G LK+ V+ ++ L VP+L
Sbjct: 210 NIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKM-VVQRDERATLLNVPDL 262
>DQ015919-1|AAY22179.1| 1748|Homo sapiens tight junction protein 1
(zona occludens 1) protein.
Length = 1748
Score = 42.7 bits (96), Expect = 0.003
Identities = 30/114 (26%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 468 AKHKTKSPQVSKRYLGITMLSLTPSILMELKMRNPEMPTDIQHGILVWKVIIGS-PAFNG 526
++ ++ SP+ +R + + + + + +N E + I V ++ S A +G
Sbjct: 162 SRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDG 221
Query: 527 GLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPEL 578
+Q GD+V+KING N TD ++E + G LK+ V+ ++ L VP+L
Sbjct: 222 NIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKM-VVQRDERATLLNVPDL 274
>BC111712-1|AAI11713.1| 1748|Homo sapiens tight junction protein 1
(zona occludens 1) protein.
Length = 1748
Score = 42.7 bits (96), Expect = 0.003
Identities = 30/114 (26%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 468 AKHKTKSPQVSKRYLGITMLSLTPSILMELKMRNPEMPTDIQHGILVWKVIIGS-PAFNG 526
++ ++ SP+ +R + + + + + +N E + I V ++ S A +G
Sbjct: 162 SRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDG 221
Query: 527 GLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPEL 578
+Q GD+V+KING N TD ++E + G LK+ V+ ++ L VP+L
Sbjct: 222 NIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKM-VVQRDERATLLNVPDL 274
>BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1797
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AL358075-5|CAI21705.1| 1798|Homo sapiens microtubule associated
serine/threonine kinase 2 protein.
Length = 1798
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AB047005-1|BAB40778.1| 1734|Homo sapiens MAST205 protein.
Length = 1734
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 1136 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 1166
>AB018350-1|BAA34527.2| 1329|Homo sapiens KIAA0807 protein protein.
Length = 1329
Score = 40.3 bits (90), Expect = 0.018
Identities = 15/31 (48%), Positives = 21/31 (67%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL+ GD++ +NG+PVH
Sbjct: 667 MVWHVEDGGPASEAGLRQGDLITHVNGEPVH 697
>L27476-1|AAA61300.1| 1116|Homo sapiens X104 protein.
Length = 1116
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>BC027985-1|AAH27985.1| 1063|Homo sapiens MAST1 protein protein.
Length = 1063
Score = 38.3 bits (85), Expect = 0.074
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL GD++ +NG+PVH
Sbjct: 492 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVH 522
>BC027592-1|AAH27592.1| 1190|Homo sapiens tight junction protein 2
(zona occludens 2) protein.
Length = 1190
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AL358113-3|CAH70868.1| 1190|Homo sapiens tight junction protein 2
(zona occludens 2) protein.
Length = 1190
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AL358113-2|CAM13389.1| 1043|Homo sapiens tight junction protein 2
(zona occludens 2) protein.
Length = 1043
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AL358113-1|CAH70867.1| 993|Homo sapiens tight junction protein 2
(zona occludens 2) protein.
Length = 993
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AF489824-1|AAM28524.1| 993|Homo sapiens tight junction protein 2
protein.
Length = 993
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AF177533-4|AAD56219.2| 1020|Homo sapiens tight junction protein
ZO-2 isoform C protein.
Length = 1020
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 318 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 373
>AF177533-3|AAC02527.2| 1167|Homo sapiens tight junction protein
ZO-2 isoform C protein.
Length = 1167
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 318 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 373
>AF177533-2|AAD56218.2| 1043|Homo sapiens tight junction protein
ZO-2 isoform A protein.
Length = 1043
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AF177533-1|AAD20387.2| 1190|Homo sapiens tight junction protein
ZO-2 isoform A protein.
Length = 1190
Score = 38.3 bits (85), Expect = 0.074
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 525 NGGLQPGDIVVKINGKPVHN--TTDIYNILESTTGSLKIDAVRGRQQINLTIVPELH 579
+G L GDI++KING N TD ++E + G L++ +R QQ L +P L+
Sbjct: 341 DGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQ-TLINIPSLN 396
>AD000092-1|AAB51171.1| 1237|Homo sapiens hypothetical human
serine-threonine protein kinase R31240_1 protein.
Length = 1237
Score = 38.3 bits (85), Expect = 0.074
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL GD++ +NG+PVH
Sbjct: 653 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVH 683
>AB023190-1|BAA76817.1| 1583|Homo sapiens KIAA0973 protein protein.
Length = 1583
Score = 38.3 bits (85), Expect = 0.074
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVH 543
+VW V G PA GL GD++ +NG+PVH
Sbjct: 1012 IVWHVEEGGPAQEAGLCAGDLITHVNGEPVH 1042
>BC108907-1|AAI08908.2| 917|Homo sapiens TJP3 protein protein.
Length = 917
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 520 GSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQINLTIVP 576
G A + GLQ GD++++ING N + D ++E + G L + +R R Q + I P
Sbjct: 223 GLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEGKLSLLVLRDRGQFLVNIPP 281
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT 546
GI V V GSPA G+Q GD ++++N P N T
Sbjct: 403 GIFVSGVQAGSPADGQGIQEGDQILQVNDVPFQNLT 438
Score = 33.1 bits (72), Expect = 2.8
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIY--NILESTTGSLKIDAVRGRQ 568
++V V+ G PA G LQ GD +V +NG + N T + IL++ T I R R+
Sbjct: 37 MVVSDVVPGGPA-EGRLQTGDHIVMVNGVSMENATSAFAIQILKTCTKMANITVKRPRR 94
>BC108906-1|AAI08907.1| 938|Homo sapiens TJP3 protein protein.
Length = 938
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 520 GSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQINLTIVP 576
G A + GLQ GD++++ING N + D ++E + G L + +R R Q + I P
Sbjct: 242 GLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEGKLSLLVLRDRGQFLVNIPP 300
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT 546
GI V V GSPA G+Q GD ++++N P N T
Sbjct: 422 GIFVSGVQAGSPADGQGIQEGDQILQVNDVPFQNLT 457
Score = 33.1 bits (72), Expect = 2.8
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIY--NILESTTGSLKIDAVRGRQ 568
++V V+ G PA G LQ GD +V +NG + N T + IL++ T I R R+
Sbjct: 56 MVVSDVVPGGPA-EGRLQTGDHIVMVNGVSMENATSAFAIQILKTCTKMANITVKRPRR 113
>AC005954-1|AAC72274.1| 952|Homo sapiens ZO-3 [Homo sapiens]
protein.
Length = 952
Score = 36.3 bits (80), Expect = 0.30
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 520 GSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQINLTIVP 576
G A + GLQ GD++++ING N + D ++E + G L + +R R Q + I P
Sbjct: 242 GLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEGKLSLLVLRDRGQFLVNIPP 300
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT 546
GI V V GSPA G+Q GD ++++N P N T
Sbjct: 436 GIFVSGVQAGSPADGQGIQEGDQILQVNDVPFQNLT 471
Score = 33.1 bits (72), Expect = 2.8
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIY--NILESTTGSLKIDAVRGRQ 568
++V V+ G PA G LQ GD +V +NG + N T + IL++ T I R R+
Sbjct: 56 MVVSDVVPGGPA-EGRLQTGDHIVMVNGVSMENATSAFAIQILKTCTKMANITVKRPRR 113
>BC118915-1|AAI18916.1| 1406|Homo sapiens ARHGAP21 protein protein.
Length = 1406
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AL392104-2|CAI40177.1| 189|Homo sapiens Rho GTPase activating
protein 21 protein.
Length = 189
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AL392104-1|CAI40176.1| 1957|Homo sapiens Rho GTPase activating
protein 21 protein.
Length = 1957
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AL355979-2|CAI14324.1| 189|Homo sapiens Rho GTPase activating
protein 21 protein.
Length = 189
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AL355979-1|CAI14323.1| 1957|Homo sapiens Rho GTPase activating
protein 21 protein.
Length = 1957
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AF480466-1|AAM22955.1| 1957|Homo sapiens Rho-GTPase activating
protein 10 protein.
Length = 1957
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 90 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 146
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 147 DTTLELSVM 155
>AB037845-1|BAA92662.2| 1944|Homo sapiens KIAA1424 protein protein.
Length = 1944
Score = 35.9 bits (79), Expect = 0.39
Identities = 22/69 (31%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 498 KMRNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILEST 555
K RN P D I V +V G PAF GL GD ++K+NG+ V T + +++++
Sbjct: 77 KQRNRLEPMDT---IFVKQVKEGGPAFEAGLCTGDRIIKVNGESVIGKTYSQVIALIQNS 133
Query: 556 TGSLKIDAV 564
+L++ +
Sbjct: 134 DTTLELSVM 142
>AY190519-1|AAO38848.1| 1692|Homo sapiens Rab3A-interacting molecule
protein.
Length = 1692
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 615 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 673
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 674 NIILESKSEPQVEIIVSRPIGDIPRIPE 701
>AL590011-1|CAI16961.1| 1039|Homo sapiens regulating synaptic
membrane exocytosis 1 protein.
Length = 1039
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 615 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 673
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 674 NIILESKSEPQVEIIVSRPIGDIPRIPE 701
>AL445256-1|CAI39598.1| 1039|Homo sapiens regulating synaptic
membrane exocytosis 1 protein.
Length = 1039
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 615 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 673
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 674 NIILESKSEPQVEIIVSRPIGDIPRIPE 701
>AL390056-1|CAI21554.1| 1039|Homo sapiens regulating synaptic
membrane exocytosis 1 protein.
Length = 1039
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 615 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 673
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 674 NIILESKSEPQVEIIVSRPIGDIPRIPE 701
>AL034373-1|CAI20558.1| 1039|Homo sapiens regulating synaptic
membrane exocytosis 1 protein.
Length = 1039
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 615 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 673
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 674 NIILESKSEPQVEIIVSRPIGDIPRIPE 701
>AC007192-1|AAD22670.1| 681|Homo sapiens KIAA0561 protein [AA
628-1308] protein.
Length = 681
Score = 35.5 bits (78), Expect = 0.52
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPV 542
+VW V GSPA GL+ GD++ ING+ V
Sbjct: 354 VVWSVEDGSPAQEAGLRAGDLITHINGESV 383
>AB051866-1|BAB87242.1| 1470|Homo sapiens RIM long form protein.
Length = 1470
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 604 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 662
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 663 NIILESKSEPQVEIIVSRPIGDIPRIPE 690
>AB045726-1|BAB87121.1| 1028|Homo sapiens RIM short form protein.
Length = 1028
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 604 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 662
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 663 NIILESKSEPQVEIIVSRPIGDIPRIPE 690
>AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein.
Length = 1308
Score = 35.5 bits (78), Expect = 0.52
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPV 542
+VW V GSPA GL+ GD++ ING+ V
Sbjct: 981 VVWSVEDGSPAQEAGLRAGDLITHINGESV 1010
>AB002338-1|BAA20798.1| 1053|Homo sapiens KIAA0340 protein.
Length = 1053
Score = 35.5 bits (78), Expect = 0.52
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 494 LMELKMRNPEMPTDIQH-GILVWKVIIGSPA-FNGGLQPGDIVVKINGKPVHNTT--DIY 549
L+ LK+ +M TD+ G + KV GS A G L+ GD V++ NGKP+ T ++Y
Sbjct: 629 LLGLKVVGGKM-TDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 687
Query: 550 NILESTTGSLKIDAVRGRQQINLTIVPE 577
NI+ + +++ + R ++ +PE
Sbjct: 688 NIILESKSEPQVEIIVSRPIGDIPRIPE 715
>BC037988-1|AAH37988.1| 904|Homo sapiens MICAL-like 2 protein.
Length = 904
Score = 35.1 bits (77), Expect = 0.69
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 197 RDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNL 230
RD AFC + H++RPD +N A K N N L
Sbjct: 31 RDGLAFCAILHRHRPDLINFSALKKENIYENNKL 64
>AK074068-1|BAB84894.1| 585|Homo sapiens FLJ00139 protein protein.
Length = 585
Score = 35.1 bits (77), Expect = 0.69
Identities = 15/34 (44%), Positives = 19/34 (55%)
Query: 197 RDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNL 230
RD AFC + H++RPD +N A K N N L
Sbjct: 44 RDGLAFCAILHRHRPDLINFSALKKENIYENNKL 77
>M59941-1|AAA18171.1| 897|Homo sapiens GM-CSF receptor beta chain
protein.
Length = 897
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTT 556
R+ ++ TD H +L W V +GSP + L PGD+ ++ K + ++ + IL S T
Sbjct: 137 RDLQISTDQDHFLLTWSVALGSPQ-SHWLSPGDLEFEVVYKRLQDSWEDAAILLSNT 192
>L06633-1|AAA16575.1| 324|Homo sapiens transcription factor
protein.
Length = 324
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQI 570
L+ K+ SPA GLQ GD++ ING T + +++ S+ L I+ + G +
Sbjct: 75 LICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMIL 134
Query: 571 NLT 573
T
Sbjct: 135 KRT 137
>CR456428-1|CAG30314.1| 903|Homo sapiens CSF2RB protein.
Length = 903
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTT 556
R+ ++ TD H +L W V +GSP + L PGD+ ++ K + ++ + IL S T
Sbjct: 137 RDLQISTDQDHFLLTWSVALGSPQ-SHWLSPGDLEFEVVYKRLQDSWEDAAILLSNT 192
>BC070085-1|AAH70085.1| 889|Homo sapiens CSF2RB protein protein.
Length = 889
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTT 556
R+ ++ TD H +L W V +GSP + L PGD+ ++ K + ++ + IL S T
Sbjct: 137 RDLQISTDQDHFLLTWSVALGSPQ-SHWLSPGDLEFEVVYKRLQDSWEDAAILLSNT 192
>BC036449-1|AAH36449.1| 359|Homo sapiens pleckstrin homology, Sec7
and coiled-coil domains, binding protein protein.
Length = 359
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQI 570
L+ K+ SPA GLQ GD++ ING T + +++ S+ L I+ + G +
Sbjct: 110 LICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMIL 169
Query: 571 NLT 573
T
Sbjct: 170 KRT 172
>AL133392-1|CAI23586.1| 897|Homo sapiens colony stimulating factor
2 receptor, beta, low-affinity (granulocyte-macrophag
protein.
Length = 897
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTT 556
R+ ++ TD H +L W V +GSP + L PGD+ ++ K + ++ + IL S T
Sbjct: 137 RDLQISTDQDHFLLTWSVALGSPQ-SHWLSPGDLEFEVVYKRLQDSWEDAAILLSNT 192
>AL008637-2|CAI17999.1| 897|Homo sapiens colony stimulating factor
2 receptor, beta, low-affinity (granulocyte-macrophag
protein.
Length = 897
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILESTT 556
R+ ++ TD H +L W V +GSP + L PGD+ ++ K + ++ + IL S T
Sbjct: 137 RDLQISTDQDHFLLTWSVALGSPQ-SHWLSPGDLEFEVVYKRLQDSWEDAAILLSNT 192
>AF068836-1|AAC19129.1| 359|Homo sapiens cytohesin binding protein
HE protein.
Length = 359
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQI 570
L+ K+ SPA GLQ GD++ ING T + +++ S+ L I+ + G +
Sbjct: 110 LICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMIL 169
Query: 571 NLT 573
T
Sbjct: 170 KRT 172
>AC019201-1|AAY14898.1| 359|Homo sapiens unknown protein.
Length = 359
Score = 34.3 bits (75), Expect = 1.2
Identities = 19/63 (30%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 513 LVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILESTTGSLKIDAVRGRQQI 570
L+ K+ SPA GLQ GD++ ING T + +++ S+ L I+ + G +
Sbjct: 110 LICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMIL 169
Query: 571 NLT 573
T
Sbjct: 170 KRT 172
>AK027292-1|BAB55020.1| 548|Homo sapiens protein ( Homo sapiens
cDNA FLJ14386 fis, clone HEMBA1002417, moderately
similar to TIGHT JUNCTION PROTEIN ZO-1. ).
Length = 548
Score = 33.5 bits (73), Expect = 2.1
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT 546
GI V V GSPA G+Q GD ++++N P N T
Sbjct: 32 GIFVSGVQAGSPADGQGIQEGDQILQVNDVPFQNLT 67
>BC104036-1|AAI04037.1| 428|Homo sapiens ARL13B protein protein.
Length = 428
Score = 33.1 bits (72), Expect = 2.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 186 LAANKINYDLPRDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNLNGVEN 235
L K N + +D + C + HK + + +V HNGQ N VEN
Sbjct: 271 LEREKKNQKMEKDSDG-CHLKHKMEHEQIETQGQVNHNGQKNNEFGLVEN 319
>BC104035-1|AAI04036.1| 428|Homo sapiens ARL13B protein protein.
Length = 428
Score = 33.1 bits (72), Expect = 2.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 186 LAANKINYDLPRDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNLNGVEN 235
L K N + +D + C + HK + + +V HNGQ N VEN
Sbjct: 271 LEREKKNQKMEKDSDG-CHLKHKMEHEQIETQGQVNHNGQKNNEFGLVEN 319
>BC094725-1|AAH94725.1| 321|Homo sapiens ADP-ribosylation
factor-like 13B protein.
Length = 321
Score = 33.1 bits (72), Expect = 2.8
Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 1/50 (2%)
Query: 186 LAANKINYDLPRDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNLNGVEN 235
L K N + +D + C + HK + + +V HNGQ N VEN
Sbjct: 164 LEREKKNQKMEKDSDG-CHLKHKMEHEQIETQGQVNHNGQKNNEFGLVEN 212
>BC029042-1|AAH29042.1| 491|Homo sapiens PDZ domain containing 3
protein.
Length = 491
Score = 33.1 bits (72), Expect = 2.8
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDI 548
+ + +V G A GLQ GD+++++NG PV D+
Sbjct: 411 LFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDL 447
>AY047359-1|AAL10686.1| 505|Homo sapiens intestinal and kidney
enriched PDZ protein protein.
Length = 505
Score = 33.1 bits (72), Expect = 2.8
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDI 548
+ + +V G A GLQ GD+++++NG PV D+
Sbjct: 425 LFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDL 461
>AB094096-1|BAC76050.1| 571|Homo sapiens DLNB27 protein.
Length = 571
Score = 33.1 bits (72), Expect = 2.8
Identities = 13/37 (35%), Positives = 22/37 (59%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDI 548
+ + +V G A GLQ GD+++++NG PV D+
Sbjct: 491 LFISQVTPGGSAARAGLQVGDVILEVNGYPVGGQNDL 527
>CR456437-1|CAG30323.1| 863|Homo sapiens dJ1014D13.2 protein.
Length = 863
Score = 32.7 bits (71), Expect = 3.7
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 197 RDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNL 230
RD AFC + H++RPD ++ D+ K N N L
Sbjct: 32 RDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRL 65
>BC025767-1|AAH25767.1| 670|Homo sapiens rhophilin, Rho GTPase
binding protein 1 protein.
Length = 670
Score = 32.7 bits (71), Expect = 3.7
Identities = 14/30 (46%), Positives = 20/30 (66%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKP 541
+L+ VI GS A GL+ GD +V +NG+P
Sbjct: 533 VLIAAVIPGSQAAAAGLKEGDYIVSVNGQP 562
>AY082588-1|AAL89809.1| 695|Homo sapiens rhophilin-1 protein.
Length = 695
Score = 32.7 bits (71), Expect = 3.7
Identities = 14/30 (46%), Positives = 20/30 (66%)
Query: 512 ILVWKVIIGSPAFNGGLQPGDIVVKINGKP 541
+L+ VI GS A GL+ GD +V +NG+P
Sbjct: 558 VLIAAVIPGSQAAAAGLKEGDYIVSVNGQP 587
>AL022311-1|CAI18864.1| 863|Homo sapiens protein ( Human DNA
sequence from clone RP5-1014D13 on chromosome
22q13.1-13.2. ).
Length = 863
Score = 32.7 bits (71), Expect = 3.7
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 197 RDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNL 230
RD AFC + H++RPD ++ D+ K N N L
Sbjct: 32 RDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRL 65
>AJ496196-1|CAD42713.1| 863|Homo sapiens molecule interacting with
Rab13 protein.
Length = 863
Score = 32.7 bits (71), Expect = 3.7
Identities = 14/34 (41%), Positives = 20/34 (58%)
Query: 197 RDDEAFCQVFHKYRPDAVNGDAKVKHNGQVNGNL 230
RD AFC + H++RPD ++ D+ K N N L
Sbjct: 32 RDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRL 65
>X80289-1|CAA56563.1| 2466|Homo sapiens protein-tyrosine-phosphatase
protein.
Length = 2466
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1792 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1851
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1852 LPRIPMLPHL 1861
>U12128-1|AAB60339.1| 2490|Homo sapiens protein tyrosine phosphatase
1E protein.
Length = 2490
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1816 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1875
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1876 LPRIPMLPHL 1885
>L34583-1|AAC41755.1| 610|Homo sapiens tyrosine phosphatase
protein.
Length = 610
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 538 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 597
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 598 LPRIPMLPHL 607
>D21211-1|BAA04752.1| 2294|Homo sapiens protein tyrosine phosphatase
type 3 protein.
Length = 2294
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1620 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1679
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1680 LPRIPMLPHL 1689
>D21210-1|BAA04751.1| 2466|Homo sapiens protein tyrosine phosphatase
type 2 protein.
Length = 2466
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1792 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1851
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1852 LPRIPMLPHL 1861
>D21209-1|BAA04750.1| 2485|Homo sapiens protein tyrosine phosphatase
type 1 protein.
Length = 2485
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1811 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1870
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1871 LPRIPMLPHL 1880
>BC039610-1|AAH39610.1| 604|Homo sapiens PTPN13 protein protein.
Length = 604
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 489 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 548
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 549 LPRIPMLPHL 558
>BC016057-1|AAH16057.1| 533|Homo sapiens USH1C protein protein.
Length = 533
Score = 32.3 bits (70), Expect = 4.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILES-TTGSLKI 561
G+ + +I G A + GLQ GD +V+ING + + T ++ N++ + T S+K+
Sbjct: 111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKV 164
>BC006518-1|AAH06518.1| 519|Homo sapiens PDZ domain containing 1
protein.
Length = 519
Score = 32.3 bits (70), Expect = 4.8
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 509 QHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILE 553
Q G ++ + GSPA GL+ D+VV +NG+ V T D +++E
Sbjct: 263 QKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESV-ETLDHDSVVE 306
>BC006496-1|AAH06496.1| 519|Homo sapiens PDZ domain containing 1
protein.
Length = 519
Score = 32.3 bits (70), Expect = 4.8
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 509 QHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILE 553
Q G ++ + GSPA GL+ D+VV +NG+ V T D +++E
Sbjct: 263 QKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESV-ETLDHDSVVE 306
>AL391240-1|CAM28242.1| 2106|Homo sapiens novel protein protein.
Length = 2106
Score = 32.3 bits (70), Expect = 4.8
Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Query: 350 DLQSDLATLRIPVKGLPTMKLGTSADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSE 409
DLQ ++ + + + PT L SA LK E + ++ V ++ + S+
Sbjct: 39 DLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSD 98
Query: 410 LGLQDR----NIVYIQTDAPITFGNSGGPLVNLDGEAIGI-----NSMKVTYGISFAIPI 460
L LQ R N + D P FGN G + +L + + + ++ S + +
Sbjct: 99 LTLQLRQRQENTIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQL 158
Query: 461 DYVKEFLA--KHKTKSPQVSKRYLGITMLSLTPSILMEL 497
Y++ L+ + S + +R+ + +L P++++ L
Sbjct: 159 LYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVIL 197
>AL390725-5|CAI13716.1| 519|Homo sapiens PDZ domain containing 1
protein.
Length = 519
Score = 32.3 bits (70), Expect = 4.8
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 509 QHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILE 553
Q G ++ + GSPA GL+ D+VV +NG+ V T D +++E
Sbjct: 263 QKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESV-ETLDHDSVVE 306
>AL031433-2|CAI19661.2| 2106|Homo sapiens novel protein protein.
Length = 2106
Score = 32.3 bits (70), Expect = 4.8
Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Query: 350 DLQSDLATLRIPVKGLPTMKLGTSADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSE 409
DLQ ++ + + + PT L SA LK E + ++ V ++ + S+
Sbjct: 39 DLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSD 98
Query: 410 LGLQDR----NIVYIQTDAPITFGNSGGPLVNLDGEAIGI-----NSMKVTYGISFAIPI 460
L LQ R N + D P FGN G + +L + + + ++ S + +
Sbjct: 99 LTLQLRQRQENTIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQL 158
Query: 461 DYVKEFLA--KHKTKSPQVSKRYLGITMLSLTPSILMEL 497
Y++ L+ + S + +R+ + +L P++++ L
Sbjct: 159 LYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVIL 197
>AL031003-5|CAM28244.1| 2106|Homo sapiens novel protein protein.
Length = 2106
Score = 32.3 bits (70), Expect = 4.8
Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 11/159 (6%)
Query: 350 DLQSDLATLRIPVKGLPTMKLGTSADLKPGEWVVAIGSPLDLSNTVTAGVVSSTQRAGSE 409
DLQ ++ + + + PT L SA LK E + ++ V ++ + S+
Sbjct: 39 DLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSD 98
Query: 410 LGLQDR----NIVYIQTDAPITFGNSGGPLVNLDGEAIGI-----NSMKVTYGISFAIPI 460
L LQ R N + D P FGN G + +L + + + ++ S + +
Sbjct: 99 LTLQLRQRQENTIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQL 158
Query: 461 DYVKEFLA--KHKTKSPQVSKRYLGITMLSLTPSILMEL 497
Y++ L+ + S + +R+ + +L P++++ L
Sbjct: 159 LYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVIL 197
>AF039700-1|AAC18049.1| 652|Homo sapiens antigen NY-CO-38 protein.
Length = 652
Score = 32.3 bits (70), Expect = 4.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILES-TTGSLKI 561
G+ + +I G A + GLQ GD +V+ING + + T ++ N++ + T S+K+
Sbjct: 111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKV 164
>AF039699-1|AAC18048.1| 403|Homo sapiens antigen NY-CO-37 protein.
Length = 403
Score = 32.3 bits (70), Expect = 4.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILES-TTGSLKI 561
G+ + +I G A + GLQ GD +V+ING + + T ++ N++ + T S+K+
Sbjct: 111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKV 164
>AF012281-1|AAC12264.1| 519|Homo sapiens PDZ domain
containing-protein protein.
Length = 519
Score = 32.3 bits (70), Expect = 4.8
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 509 QHGILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTDIYNILE 553
Q G ++ + GSPA GL+ D+VV +NG+ V T D +++E
Sbjct: 263 QKGQIIKDIDSGSPAEEAGLKNNDLVVAVNGESV-ETLDHDSVVE 306
>AC105413-1|AAY40972.1| 1305|Homo sapiens unknown protein.
Length = 1305
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 631 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 690
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 691 LPRIPMLPHL 700
>AB208904-1|BAD92141.1| 2434|Homo sapiens protein tyrosine
phosphatase, non-receptor type 13 isoform 2 variant
protein.
Length = 2434
Score = 32.3 bits (70), Expect = 4.8
Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNT--TDIYNILESTTGSLKIDAVRGRQ 568
G V VI +G L+PGD ++K+N V N TD N+L + + ++++ R +
Sbjct: 1760 GCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLE 1819
Query: 569 QINLTIVPEL 578
+ ++P L
Sbjct: 1820 LPRIPMLPHL 1829
>AB018687-1|BAA81740.1| 552|Homo sapiens autoimmune
enteropathy-related antigen AIE-75 protein.
Length = 552
Score = 32.3 bits (70), Expect = 4.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILES-TTGSLKI 561
G+ + +I G A + GLQ GD +V+ING + + T ++ N++ + T S+K+
Sbjct: 111 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKV 164
>AB006955-1|BAA81739.1| 521|Homo sapiens AIE-75 protein.
Length = 521
Score = 32.3 bits (70), Expect = 4.8
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTT--DIYNILES-TTGSLKI 561
G+ + +I G A + GLQ GD +V+ING + + T ++ N++ + T S+K+
Sbjct: 80 GLFISHLIKGGQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKV 133
>BC023980-1|AAH23980.1| 124|Homo sapiens Tax1 (human T-cell
leukemia virus type I) binding protein 3 protein.
Length = 124
Score = 31.9 bits (69), Expect = 6.4
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKING 539
+NP GI V +V G PA GLQ GD ++++NG
Sbjct: 43 QNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNG 82
>AF277318-1|AAK69111.1| 124|Homo sapiens tax-interacting protein 1
protein.
Length = 124
Score = 31.9 bits (69), Expect = 6.4
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKING 539
+NP GI V +V G PA GLQ GD ++++NG
Sbjct: 43 QNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNG 82
>AF234997-1|AAG44368.1| 124|Homo sapiens glutaminase-interacting
protein 3 protein.
Length = 124
Score = 31.9 bits (69), Expect = 6.4
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKING 539
+NP GI V +V G PA GLQ GD ++++NG
Sbjct: 43 QNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNG 82
>AF168787-3|AAF43104.1| 116|Homo sapiens TIP1 protein.
Length = 116
Score = 31.9 bits (69), Expect = 6.4
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKING 539
+NP GI V +V G PA GLQ GD ++++NG
Sbjct: 35 QNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNG 74
>AF028823-1|AAB84248.2| 124|Homo sapiens Tax interaction protein 1
protein.
Length = 124
Score = 31.9 bits (69), Expect = 6.4
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 500 RNPEMPTDIQHGILVWKVIIGSPAFNGGLQPGDIVVKING 539
+NP GI V +V G PA GLQ GD ++++NG
Sbjct: 43 QNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNG 82
>U61843-1|AAC61295.1| 674|Homo sapiens discs large protein P-dlg
protein.
Length = 674
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 126 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 162
>BC073996-1|AAH73996.1| 845|Homo sapiens DLG5 protein protein.
Length = 845
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 297 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 333
>AL450306-3|CAI17324.2| 1919|Homo sapiens discs, large homolog 5
(Drosophila) protein.
Length = 1919
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1371 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1407
>AL450306-2|CAI17323.1| 880|Homo sapiens discs, large homolog 5
(Drosophila) protein.
Length = 880
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 332 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 368
>AL391421-2|CAI12104.2| 1919|Homo sapiens discs, large homolog 5
(Drosophila) protein.
Length = 1919
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1371 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1407
>AL391421-1|CAI12103.1| 880|Homo sapiens discs, large homolog 5
(Drosophila) protein.
Length = 880
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 332 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 368
>AF352034-1|AAL83938.1| 1809|Homo sapiens DLG5 protein.
Length = 1809
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1261 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1297
>AF352033-1|AAL83937.1| 1809|Homo sapiens DLG5 protein.
Length = 1809
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1261 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1297
>AB091676-1|BAC65420.1| 1764|Homo sapiens discs large protein lp-dlg
protein.
Length = 1764
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1216 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1252
>AB011155-1|BAA25509.2| 1952|Homo sapiens KIAA0583 protein protein.
Length = 1952
Score = 31.5 bits (68), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 511 GILVWKVIIGSPAFNGGLQPGDIVVKINGKPVHNTTD 547
GI V KV +GS A GL+ GD +++ NG + + T+
Sbjct: 1404 GIYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATE 1440
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,993,838
Number of Sequences: 224733
Number of extensions: 2965154
Number of successful extensions: 5721
Number of sequences better than 10.0: 129
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 5449
Number of HSP's gapped (non-prelim): 230
length of query: 579
length of database: 73,234,838
effective HSP length: 94
effective length of query: 485
effective length of database: 52,109,936
effective search space: 25273318960
effective search space used: 25273318960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
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