Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002295-TA|BGIBMGA002295-PA|IPR002698|5-
formyltetrahydrofolate cyclo-ligase
(270 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56FA8 Cluster: PREDICTED: similar to CG14648-PA... 283 4e-75
UniRef50_UPI0000DB6C87 Cluster: PREDICTED: similar to CG14648-PA... 272 5e-72
UniRef50_Q2M296 Cluster: Methenyltetrahydrofolate synthetase dom... 242 6e-63
UniRef50_Q2KI24 Cluster: Methenyltetrahydrofolate synthetase dom... 241 1e-62
UniRef50_A7Q789 Cluster: Chromosome chr18 scaffold_59, whole gen... 214 2e-54
UniRef50_Q17J32 Cluster: Putative uncharacterized protein; n=2; ... 212 7e-54
UniRef50_Q9VN21 Cluster: CG14648-PA, isoform A; n=4; Sophophora|... 207 2e-52
UniRef50_Q67KJ7 Cluster: Putative 5-formyltetrahydrofolate cyclo... 202 1e-50
UniRef50_Q704B8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 200 2e-50
UniRef50_Q4SIK4 Cluster: Chromosome 5 SCAF14581, whole genome sh... 197 2e-49
UniRef50_UPI00015B44D2 Cluster: PREDICTED: similar to RH35990p; ... 196 5e-49
UniRef50_Q4JBH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 187 2e-46
UniRef50_A2BIS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 186 7e-46
UniRef50_Q9KEL6 Cluster: BH0836 protein; n=1; Bacillus haloduran... 183 5e-45
UniRef50_Q5UXE1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 180 3e-44
UniRef50_Q7PRT0 Cluster: ENSANGP00000019134; n=1; Anopheles gamb... 165 8e-40
UniRef50_Q8TUZ6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 162 1e-38
UniRef50_UPI00015BAEF9 Cluster: 5-formyltetrahydrofolate cyclo-l... 160 4e-38
UniRef50_Q2JBX8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 159 5e-38
UniRef50_A1RWD1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 157 4e-37
UniRef50_A7D5P9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 124 2e-27
UniRef50_O26306 Cluster: Conserved protein; n=1; Methanothermoba... 118 2e-25
UniRef50_A6X384 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 108 1e-22
UniRef50_A6X380 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 106 7e-22
UniRef50_A0LFH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l... 82 1e-14
UniRef50_Q16IS3 Cluster: Putative uncharacterized protein; n=3; ... 82 2e-14
UniRef50_Q0V4P7 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_A7ERE4 Cluster: Putative uncharacterized protein; n=1; ... 73 1e-11
UniRef50_Q5SLW0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 72 1e-11
UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_A1G3P7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 3e-06
UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 52 1e-05
UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 51 3e-05
UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 51 4e-05
UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 51 4e-05
UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate cyclo... 50 8e-05
UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 50 8e-05
UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 49 1e-04
UniRef50_A6PRD6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 48 2e-04
UniRef50_Q47T07 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_A6WEB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 48 3e-04
UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 48 3e-04
UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 48 3e-04
UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 47 4e-04
UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni ACN1... 47 6e-04
UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 46 8e-04
UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23; Ent... 46 8e-04
UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 0.001
UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 46 0.001
UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 0.001
UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.002
UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;... 45 0.002
UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.002
UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.002
UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 45 0.002
UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 44 0.003
UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 44 0.003
UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 44 0.003
UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ... 44 0.003
UniRef50_Q4FR52 Cluster: Possible 5-formyltetrahydrofolate cyclo... 44 0.004
UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 44 0.004
UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 43 0.007
UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 43 0.007
UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 43 0.007
UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 43 0.010
UniRef50_Q1NLL0 Cluster: Putative 5-formyltetrahydrofolate cyclo... 43 0.010
UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 42 0.013
UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.013
UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.013
UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.013
UniRef50_A0LR79 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.013
UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate cyclo... 42 0.017
UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.017
UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.017
UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1; ... 42 0.022
UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1; ... 42 0.022
UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.022
UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.022
UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 41 0.029
UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 41 0.029
UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 41 0.038
UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 41 0.038
UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 41 0.038
UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 41 0.038
UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 41 0.038
UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC ... 40 0.051
UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.051
UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.051
UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.067
UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.067
UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4; ... 40 0.067
UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.089
UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.12
UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.12
UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.12
UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.12
UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.12
UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2; ... 39 0.16
UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.16
UniRef50_A1A037 Cluster: Putative uncharacterized protein; n=2; ... 39 0.16
UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate cyclo... 38 0.20
UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2; ... 38 0.20
UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.20
UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 38 0.20
UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.20
UniRef50_Q0S4X5 Cluster: Putative uncharacterized protein; n=1; ... 38 0.20
UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.20
UniRef50_A6S505 Cluster: Predicted protein; n=1; Botryotinia fuc... 38 0.20
UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.20
UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 38 0.27
UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.27
UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.36
UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1; ... 38 0.36
UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.36
UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 38 0.36
UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 37 0.47
UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 37 0.47
UniRef50_Q6MNQ4 Cluster: InterPro: 5-formyltetrahydrofolate cycl... 37 0.47
UniRef50_Q2GER3 Cluster: 5,10-methenyltetrahydrofolate synthetas... 37 0.47
UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 37 0.47
UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2; Baci... 37 0.47
UniRef50_Q98N02 Cluster: Mll0364 protein; n=4; Rhizobiales|Rep: ... 37 0.63
UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 37 0.63
UniRef50_Q2RVG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 37 0.63
UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 37 0.63
UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 37 0.63
UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 37 0.63
UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 37 0.63
UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyc... 37 0.63
UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 0.83
UniRef50_A6E7D7 Cluster: Thiol:disulfide interchange protein; n=... 36 0.83
UniRef50_A4KQQ5 Cluster: 5-formyltetrahydroformate cycloligase; ... 36 0.83
UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 0.83
UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2; Ostre... 36 0.83
UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 0.83
UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1; ... 36 0.83
UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 0.83
UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 1.1
UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 36 1.1
UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 36 1.1
UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 1.1
UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 1.4
UniRef50_Q82Y32 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 1.4
UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 36 1.4
UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp.... 36 1.4
UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 1.4
UniRef50_Q6AAH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 1.9
UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 35 1.9
UniRef50_A7I2Y8 Cluster: 5,10-methenyltetrahydrofolate synthetas... 35 1.9
UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 1.9
UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 35 1.9
UniRef50_Q4ULB4 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 35 2.5
UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 2.5
UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1; ... 35 2.5
UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 2.5
UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.5
UniRef50_A3B6X0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.3
UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to 5-formylte... 34 4.4
UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate cyclo... 34 4.4
UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 34 4.4
UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 34 4.4
UniRef50_Q92HS7 Cluster: Similarity to 5-formyltetrahydrofolate ... 33 5.8
UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep... 33 5.8
UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetas... 33 5.8
UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_A5FXW4 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8
UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_A1AXM1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.8
UniRef50_A3H8G1 Cluster: DNA topoisomerase; n=1; Caldivirga maqu... 33 5.8
UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1; ... 33 5.8
UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein Rgryl_01000... 33 7.7
UniRef50_Q89U90 Cluster: Blr1527 protein; n=1; Bradyrhizobium ja... 33 7.7
UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 33 7.7
UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 7.7
UniRef50_A3T1K0 Cluster: Putative uncharacterized protein; n=2; ... 33 7.7
UniRef50_A0PYT7 Cluster: Leucine Rich Repeat domain protein; n=4... 33 7.7
UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l... 33 7.7
>UniRef50_UPI0000D56FA8 Cluster: PREDICTED: similar to CG14648-PA,
isoform A; n=2; Coelomata|Rep: PREDICTED: similar to
CG14648-PA, isoform A - Tribolium castaneum
Length = 461
Score = 283 bits (693), Expect = 4e-75
Identities = 129/242 (53%), Positives = 179/242 (73%), Gaps = 1/242 (0%)
Query: 26 EEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVN 85
E+ +KQS+R KVW +LE N L FPRP + RIPNFKGA +AAA+L +L+ FKNA +V+VN
Sbjct: 22 EDNSKQSFRKKVWDYLEKNKLVNFPRPAFGRIPNFKGADKAAAQLLQLEEFKNAKSVEVN 81
Query: 86 PDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGK 145
PDKP E R + +E KTLYVPVPRLQ G L ++ E + P +++ V+R G+ET GK
Sbjct: 82 PDKPLEAARSLVIESDKTLYVPVPRLQEGLLKKIAFCEADK-PKNVKQTVTRWGIETLGK 140
Query: 146 PIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
+ D + +DL+V+GSVAVS++G RIGKGRGY DLE+ ++ MKA+ +T +VTTVHD
Sbjct: 141 AVDFGDGLHIDLLVLGSVAVSRDGRRIGKGRGYADLEYAILKEMKAVDDNTTIVTTVHDS 200
Query: 206 QVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLR 265
QVFD LP+++F +DVP+D I+TPTQ+I+ ++ RP GI W +LS RRL LMP+L +++
Sbjct: 201 QVFDCLPSDIFKKYDVPLDYILTPTQIIKVEKKLTRPEGIYWDILSQRRLSLMPVLQKIK 260
Query: 266 DI 267
+I
Sbjct: 261 EI 262
>UniRef50_UPI0000DB6C87 Cluster: PREDICTED: similar to CG14648-PA,
isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
to CG14648-PA, isoform A - Apis mellifera
Length = 449
Score = 272 bits (668), Expect = 5e-72
Identities = 124/249 (49%), Positives = 174/249 (69%), Gaps = 1/249 (0%)
Query: 20 TKKPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNA 79
T+K LP+EVTK S+R KVW +L N L FP VY+RIPNFKGA EAA +LAELD FK A
Sbjct: 2 TEKQLPQEVTKHSFRQKVWDYLMKNDLVNFPLSVYDRIPNFKGAIEAAQRLAELDNFKQA 61
Query: 80 NTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNG 139
+K+NPDK QEPVR + L K + VP+P+L++G + P +R +G
Sbjct: 62 KIIKINPDKSQEPVRFLALVANKEILVPIPKLRSGLFLHIT-PIAGASKNELRMLSKIHG 120
Query: 140 METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
+ GKP+ I + +DLV++GSV VS++GYR+GKG+G+ DLEF +MM M A+ DT+V+
Sbjct: 121 LTKVGKPLDINSKIKIDLVILGSVCVSRDGYRLGKGKGFADLEFAMMMRMGAVTQDTIVI 180
Query: 200 TTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMP 259
TTVHDCQVFD+LP ++F +DVP+DIIVTPT+ I ++P I+WH+LS R+++ M
Sbjct: 181 TTVHDCQVFDSLPHQIFKEYDVPVDIIVTPTETIIVNPKLKKPNCIIWHVLSERKIKSME 240
Query: 260 ILGQLRDIE 268
+L QL++++
Sbjct: 241 VLQQLKEMD 249
>UniRef50_Q2M296 Cluster: Methenyltetrahydrofolate synthetase
domain-containing protein; n=30; Euteleostomi|Rep:
Methenyltetrahydrofolate synthetase domain-containing
protein - Homo sapiens (Human)
Length = 383
Score = 242 bits (593), Expect = 6e-63
Identities = 117/244 (47%), Positives = 162/244 (66%), Gaps = 2/244 (0%)
Query: 22 KPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANT 81
+P V+KQ R ++W ++E+ LA FPRPV++RIPNFKG+ A + +LDVF
Sbjct: 2 EPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQE 61
Query: 82 VKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGME 141
VKV+PDKP E VR++ L+ +KTL VP PRL+TG N++ P G T +RK + G+
Sbjct: 62 VKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVR 120
Query: 142 TYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
Y PIG++ V +DLVV+GSVAVS++G+RIGKG GY DLE+ +M+ M A+ +T VVT
Sbjct: 121 NYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTI 180
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPIL 261
VHDCQV D +P EL HD+ +D I+TPT+VI T +P GI W +S ++ +PIL
Sbjct: 181 VHDCQVVD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPIL 239
Query: 262 GQLR 265
LR
Sbjct: 240 RSLR 243
>UniRef50_Q2KI24 Cluster: Methenyltetrahydrofolate synthetase
domain-containing protein; n=4; Eutheria|Rep:
Methenyltetrahydrofolate synthetase domain-containing
protein - Bos taurus (Bovine)
Length = 380
Score = 241 bits (591), Expect = 1e-62
Identities = 119/241 (49%), Positives = 155/241 (64%), Gaps = 2/241 (0%)
Query: 28 VTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPD 87
V+KQ R ++W ++E+ LA FPRPV++RIPNFKGA AA L FK A T+KVNPD
Sbjct: 7 VSKQDIREQIWDYMESQNLADFPRPVHHRIPNFKGASRAAEHFPRLQAFKMARTIKVNPD 66
Query: 88 KPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
PQ+ R LE +KTL VP PRL+TG N++ P G T +RK + G+ Y P+
Sbjct: 67 APQKNARFFVLESKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVRNYSTPV 125
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
G++ V +DLVV+GSVAVS++G+RIGKG GY DLE+ +M+ M A+ T VVT VHDCQV
Sbjct: 126 GLDSKVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSQGTPVVTIVHDCQV 185
Query: 208 FDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLRDI 267
D +P L HD+ +D I+TPT+VI T +P GI W +S L MPIL LR
Sbjct: 186 VD-IPEALLEDHDLTVDYILTPTRVITTGCERPKPAGIAWSKISCEMLGKMPILRSLRHQ 244
Query: 268 E 268
E
Sbjct: 245 E 245
>UniRef50_A7Q789 Cluster: Chromosome chr18 scaffold_59, whole genome
shotgun sequence; n=6; Magnoliophyta|Rep: Chromosome
chr18 scaffold_59, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 351
Score = 214 bits (523), Expect = 2e-54
Identities = 110/233 (47%), Positives = 149/233 (63%), Gaps = 3/233 (1%)
Query: 34 RVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKPQEPV 93
R +VW +ET +A PRPV++RIPNF GA AA KL L+ F A VKVNPD PQ+ V
Sbjct: 94 RKRVWDFMETRNIAQNPRPVHHRIPNFVGAAAAAQKLGGLEAFGVAKCVKVNPDSPQKQV 153
Query: 94 RVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTV 153
R + L K L P PRL+TGF + LE P+ I +A + G+ YG+PIG+++ +
Sbjct: 154 RFLTLSGGKKLLTPQPRLRTGFFSVLE--SSMLTPSTINEACTSVGVAKYGRPIGLDEQI 211
Query: 154 SLDLVVMGSVAVS-KEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
+DL+V+GSVAV K G R+GKG G+ +LE+G++ +M AI T +VT+VHD Q+ D +P
Sbjct: 212 KVDLIVIGSVAVDPKTGARLGKGEGFAELEYGMLRYMGAIDDTTPIVTSVHDEQLVDDIP 271
Query: 213 AELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLR 265
E HDVP+DII TPTQVI T +P GI W LS +L + IL +L+
Sbjct: 272 VEKLLIHDVPVDIICTPTQVIFTNTSIPKPQGIYWDKLSPEKLGQIRILRELK 324
>UniRef50_Q17J32 Cluster: Putative uncharacterized protein; n=2;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 425
Score = 212 bits (518), Expect = 7e-54
Identities = 105/244 (43%), Positives = 160/244 (65%), Gaps = 2/244 (0%)
Query: 27 EVTKQSYRVKVWRHLETNGLAVFPR-PVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVN 85
EVTK+S R++ W+ ++ L R V+N+IPN+ GA++AA LAE + FK AN++KVN
Sbjct: 1 EVTKRSIRLETWQKIKDQKLTPLRRFSVFNKIPNYIGAEKAAELLAETEEFKKANSIKVN 60
Query: 86 PDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLE-LPEGETGPAAIRKAVSRNGMETYG 144
D QEPV++ ++ +KTL+VP + + +++ E A +K + G E
Sbjct: 61 IDLAQEPVKLEVVKAKKTLFVPPAQKSSNVYAKIKNCNPDEQDLATQKKIIKLQGEEDTF 120
Query: 145 KPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
+ I + LD+VV+GS AVS++G+RIGKG GY DL+ G++ H+ I DT++VTTVHD
Sbjct: 121 QEIDMHGIEKLDMVVVGSCAVSRQGHRIGKGNGYVDLDIGILTHLGVITKDTLIVTTVHD 180
Query: 205 CQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
QV+DTLP LF +D+ +D+IVTPT+VI + RP GI W LLS+RRL+++P+L +
Sbjct: 181 VQVYDTLPENLFQTYDLSLDLIVTPTEVIRVSKRLPRPAGIEWKLLSSRRLEIVPVLKCI 240
Query: 265 RDIE 268
++ E
Sbjct: 241 KEFE 244
>UniRef50_Q9VN21 Cluster: CG14648-PA, isoform A; n=4;
Sophophora|Rep: CG14648-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 545
Score = 207 bits (506), Expect = 2e-52
Identities = 100/261 (38%), Positives = 161/261 (61%), Gaps = 3/261 (1%)
Query: 8 QNGDGTPTAVDNTKKPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAA 67
+NG T V +T +P+ E TK+S RV+ W+ ++ + + ++NRIP+F GA +AA
Sbjct: 14 ENGGNTAQEVSSTTQPI--EPTKRSLRVQTWKKIQEGKVGIGFNNIFNRIPSFVGADKAA 71
Query: 68 AKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETG 127
A A + FK A +KVN D+ + + L K++Y+P R + ++++ T
Sbjct: 72 ALFANEEEFKKAQHIKVNIDRVLHEFKELALLADKSVYLPSTRESSALCLKVDVLADATE 131
Query: 128 PAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMM 187
++A+ ++ + IG++ + LD+VV+GSV VS+EGYRIG+G G+ DL+ GL++
Sbjct: 132 EQK-KEALRVQDIQKFRSEIGLDSGLKLDIVVIGSVVVSREGYRIGRGNGFADLDIGLLI 190
Query: 188 HMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILW 247
+ AI P T++VT VHD QV D+LP LF +D P+DII TPT++I + P G+ W
Sbjct: 191 ELGAITPKTIIVTIVHDMQVVDSLPPNLFQKYDTPVDIIATPTEIIRVPKRLSFPNGVYW 250
Query: 248 HLLSNRRLQLMPILGQLRDIE 268
LLS RRL+++P+L QL++ E
Sbjct: 251 ELLSERRLKILPVLQQLKERE 271
>UniRef50_Q67KJ7 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=1; Symbiobacterium thermophilum|Rep:
Putative 5-formyltetrahydrofolate cyclo-ligase -
Symbiobacterium thermophilum
Length = 246
Score = 202 bits (492), Expect = 1e-50
Identities = 110/245 (44%), Positives = 147/245 (60%), Gaps = 11/245 (4%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
K R VW L G A FP+PV+ RIPNF G+ AAA+L EL+V++ A VKV PD P
Sbjct: 3 KGQIRQWVWDELTRRGQAAFPKPVHGRIPNFVGSAAAAARLRELEVYRQARVVKVGPDSP 62
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGI 149
P+R + L K LY+P PRL GF+ + EG P R+A S +G+ + +
Sbjct: 63 LHPIRAMVLRDGKKLYMPTPRLTAGFV----VLEG-VEPGREREATSLTNFRRFGREVRL 117
Query: 150 EDTVSLDLVVMGSVAVSKE-GYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVF 208
E+ +DLVV G+VAVS+ G RIGKG GYGD+EF L+ + ++PDT VVT VHD QV
Sbjct: 118 EEIDPIDLVVAGTVAVSQSTGVRIGKGAGYGDMEFALLCRLGKLRPDTPVVTAVHDLQVV 177
Query: 209 DT----LPAEL-FGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQ 263
D L EL + PHD+ +D IVTPT+ I +R +PT I W LL RL+ + L +
Sbjct: 178 DAPDHPLGVELPWDPHDISVDYIVTPTRTIAVRRAHPQPTEIDWSLLEPERLRALQPLLE 237
Query: 264 LRDIE 268
LR ++
Sbjct: 238 LRRMQ 242
>UniRef50_Q704B8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Thermoproteaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Thermoproteus tenax
Length = 255
Score = 200 bits (489), Expect = 2e-50
Identities = 104/238 (43%), Positives = 146/238 (61%), Gaps = 8/238 (3%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
KQ+ R ++WR LE GLA FP+PVY RIPNF G+ +A + A L F A TVK+NPD P
Sbjct: 19 KQAVRERIWRLLEERGLAAFPKPVYGRIPNFVGSDKACDRAAALPEFARARTVKINPDAP 78
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGI 149
Q R + L+ K L VP PR++ GF L L A R+A + G +G+P
Sbjct: 79 QRMCRELALKSGKVLVVPTPRIRGGF---LLLDPSAIPRDAYREASTIGGAAKWGRPTPP 135
Query: 150 EDTVSLDLVVMGSVAVS-KEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQ-V 207
E +DLV++GSVAV+ K G R+GK GY ++E+G++ + + T VVTTVHD Q V
Sbjct: 136 EHLPQIDLVIIGSVAVNPKTGRRLGKSHGYAEIEWGILSYYGKVGESTPVVTTVHDVQLV 195
Query: 208 FDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLR 265
D +P E P D+P+DI+VTPT+ + T R +P+GILW ++ L+ +P+L +LR
Sbjct: 196 DDDIPRE---PFDLPVDIVVTPTRALRTSRTDMKPSGILWEYVTEDMLREIPLLAELR 250
>UniRef50_Q4SIK4 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=3; Deuterostomia|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 462
Score = 197 bits (481), Expect = 2e-49
Identities = 97/211 (45%), Positives = 140/211 (66%), Gaps = 4/211 (1%)
Query: 58 PNFKGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLN 117
P +GA A +++ EL VF A VKV+PDKP + R+ L+ +KTL VP PRL+TG N
Sbjct: 91 PPTQGAPAACSRVPELQVFSQAAEVKVDPDKPLQGARLAVLQARKTLLVPTPRLRTGLFN 150
Query: 118 RLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRG 177
++ P G + +R S G++ + P+G++ TV +DLVV+GSVAVS++G+RIGKG G
Sbjct: 151 KITPPRGAS-KEQLRICSSSQGVKEFSLPVGLDATVKVDLVVVGSVAVSEKGFRIGKGEG 209
Query: 178 YGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
+ D+E+G+M M A+ TVVVT VHDCQV + +P EL HD+ +D I+TPTQVI+T
Sbjct: 210 FADMEYGMMASMGAVSDSTVVVTIVHDCQVVN-IPEELVDSHDLTVDYILTPTQVIKTNC 268
Query: 238 MSQRPTGILWHLLSNRRLQLMPILGQLRDIE 268
+P GI+W +L+ +PIL +LR +E
Sbjct: 269 QHPKPQGIIWS--KAEKLEKVPILQRLRSLE 297
Score = 64.5 bits (150), Expect = 3e-09
Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 9/71 (12%)
Query: 29 TKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDK 88
+K R KVW ++E LA FPRPV++RIPNFK A+L F ++ TVKVNPD+
Sbjct: 12 SKWDIRQKVWDYIEGKDLANFPRPVHHRIPNFK---------ADLREFSSSQTVKVNPDR 62
Query: 89 PQEPVRVICLE 99
PQ+ R LE
Sbjct: 63 PQQQARFATLE 73
>UniRef50_UPI00015B44D2 Cluster: PREDICTED: similar to RH35990p;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
RH35990p - Nasonia vitripennis
Length = 606
Score = 196 bits (478), Expect = 5e-49
Identities = 99/243 (40%), Positives = 149/243 (61%), Gaps = 14/243 (5%)
Query: 29 TKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDK 88
TKQ +R KVW H+ L+ R + +R P FK A EA +L EL+ K + + ++PDK
Sbjct: 153 TKQDFRKKVWCHMAEKRLSNSFRSLCSRTPFFKRATEATKRLCELEELKKSKLLMISPDK 212
Query: 89 PQEPVRVICLEQQKTLYVPVPRLQTGFLNRLE----LPEGETGPAAIRKAVSRNGMETYG 144
V ++ L+++K + +P PRL G + ++ LPE E+ + ++RN ++
Sbjct: 213 F---VILLPLKKEKEILIPTPRLFNGLFSHIKNAAGLPEEES-----KNVITRNNIKQIE 264
Query: 145 KPIGIEDTVSL--DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTV 202
P+ + T L D++++GSV V++ GYRIG G G+ DLE+ ++ MKA+ T VVT V
Sbjct: 265 SPVNFDTTTDLKVDMLILGSVCVNRAGYRIGDGAGFADLEYAILSKMKAVNEKTTVVTLV 324
Query: 203 HDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILG 262
HDCQ+ D LP ELF PHDVP+DII+TPTQ I +PT I+W +S RRL MP+LG
Sbjct: 325 HDCQILDDLPNELFEPHDVPVDIIITPTQTIFVNPRLPKPTEIIWPAISKRRLAGMPVLG 384
Query: 263 QLR 265
+++
Sbjct: 385 EIK 387
>UniRef50_Q4JBH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Sulfolobaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Sulfolobus acidocaldarius
Length = 242
Score = 187 bits (456), Expect = 2e-46
Identities = 99/234 (42%), Positives = 143/234 (61%), Gaps = 8/234 (3%)
Query: 28 VTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPD 87
++K R K+W LE +A FPRPV+ RIPNFKG++EAA +L E+ ++ A +KVNPD
Sbjct: 5 LSKAEIREKIWSLLEDKNIASFPRPVFGRIPNFKGSKEAALRLREIVEYRKAKVLKVNPD 64
Query: 88 KPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
PQ VR L KT+ VP PRL+ GF L P + + +KA + +G G+ +
Sbjct: 65 SPQRWVREFALIDGKTVLVPTPRLKGGFY--LLDP---SKISDYKKASTISGFIYLGELV 119
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
I +DLVV+GSVA++ G R+GKG GY +LE+ ++ + I T VVTT+HD Q+
Sbjct: 120 DIYSIPKVDLVVVGSVALTSRGDRVGKGEGYSELEYAILREIGKIDETTPVVTTIHDIQI 179
Query: 208 FDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPIL 261
D +P E+F DVP+DIIVTPT+V+ T ++P GI L+ +++ P L
Sbjct: 180 VDEIPTEVF---DVPVDIIVTPTKVVYTTNKREKPKGIYIEYLTKEKIEDTPFL 230
>UniRef50_A2BIS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=8; Thermoprotei|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Hyperthermus butylicus (strain DSM 5456 /
JCM 9403)
Length = 255
Score = 186 bits (452), Expect = 7e-46
Identities = 100/239 (41%), Positives = 143/239 (59%), Gaps = 12/239 (5%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
K+ R +WR L G+A FP P + RIPNF+GA+ AAAKL +L ++ A VK NPD P
Sbjct: 12 KKRLREHIWRLLSERGVATFPPP-WGRIPNFRGAEAAAAKLFDLGEWRRARIVKANPDSP 70
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAI-RKAVSRNGMETYGKPIG 148
Q VR+ L Q K L + PRL GF+ L + + P+ + KA + G G+ IG
Sbjct: 71 QRWVRLATLRQGKLLVMATPRLHEGFI----LLDPKRIPSYLYEKASTIRGAFQLGRVIG 126
Query: 149 IEDTVSL---DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
I++ SL D +V GSVAV + G+R+GKG GY +LE+ +M + + DT + TTVHD
Sbjct: 127 IDELRSLGGIDFIVTGSVAVDRYGHRVGKGEGYAELEYAIMRELGLVDEDTPIATTVHDL 186
Query: 206 QVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
Q+ D +P E P+D+ +D I TPT++I RP G++W LL +L+ +PIL +L
Sbjct: 187 QIVDHIPRE---PYDLTVDFIATPTRLIRVAERGPRPPGVIWELLPCEKLKEIPILVEL 242
>UniRef50_Q9KEL6 Cluster: BH0836 protein; n=1; Bacillus
halodurans|Rep: BH0836 protein - Bacillus halodurans
Length = 238
Score = 183 bits (445), Expect = 5e-45
Identities = 101/241 (41%), Positives = 148/241 (61%), Gaps = 13/241 (5%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
KQ+ R ++W+ + + FP P+ RIPNFKGA++A L +L+ +K A VKVNPD P
Sbjct: 4 KQAIREQMWQEMTEKKVGRFPFPLKGRIPNFKGAEQATRHLIQLEAYKQAKVVKVNPDSP 63
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGF-LNRLE-LPEGETGPAAIRKAVSRNGMETYGKPI 147
Q P+R L KTL VP PRL+ GF L + E +PEGE RKAVS + +YGK I
Sbjct: 64 QLPLRAQVLMDGKTLLVPTPRLKDGFILVKPEWVPEGEE-----RKAVSLRNILSYGKVI 118
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
+ + +DL+VMGSVAV + G RIGKG GY D E+ ++ + +P VVTTVH Q+
Sbjct: 119 SLTEMPEIDLIVMGSVAVDRSGRRIGKGEGYADREYAIIREL-GNRP-VPVVTTVHQVQL 176
Query: 208 FDT-LPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLRD 266
D LP + + DV +D I T ++++ ++PTGI+W ++ L+ MP+L ++R+
Sbjct: 177 VDVELPRDAY---DVTVDWIATTEGLMQSVGAIEKPTGIVWSEVTEEELEAMPVLREIRE 233
Query: 267 I 267
+
Sbjct: 234 L 234
>UniRef50_Q5UXE1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; cellular organisms|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 242
Score = 180 bits (438), Expect = 3e-44
Identities = 102/241 (42%), Positives = 136/241 (56%), Gaps = 8/241 (3%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
KQ+ R VW LE G+A FP P ++RIPNF+GA EAA +L E V+ A TVK NPD P
Sbjct: 3 KQTIRETVWDALEEGGIARFPFPPHDRIPNFEGASEAAQRLTETAVWDAAETVKANPDSP 62
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGI 149
Q PVR L KT+Y+ VPRL+ EL E AVS + + + +G
Sbjct: 63 QLPVRRAALRAGKTVYMAVPRLRDEQC-FYELDPAELDDIEAAPAVS--NVADHARQVGP 119
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
E S+DLVV GSVAV+++G RIGKG GY DLE+ ++ + + T VVTTVH+ Q+
Sbjct: 120 EAVGSVDLVVSGSVAVTEDGARIGKGEGYSDLEYAVLRELGLVDETTPVVTTVHELQIVG 179
Query: 210 TLPAEL-----FGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
L + HDVP+D +VTP + +ET P G+ W LS R+ +P+L
Sbjct: 180 GLEGVVDTTVPVDDHDVPMDWVVTPERTVETATTHTTPAGVDWGALSTERIDEIPVLSAR 239
Query: 265 R 265
R
Sbjct: 240 R 240
>UniRef50_Q7PRT0 Cluster: ENSANGP00000019134; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019134 - Anopheles gambiae
str. PEST
Length = 423
Score = 165 bits (402), Expect = 8e-40
Identities = 99/248 (39%), Positives = 149/248 (60%), Gaps = 16/248 (6%)
Query: 29 TKQSYRVKVWRHLETNGLAVFPRP------VYNRIPNFKGAQEAAAKLAELDVFKNANTV 82
+K+ YR +VW ++ A+FP+ V +IP F A++ A +LAE FK A +
Sbjct: 2 SKRFYRQQVWTTMK----ALFPQGSASSNYVNRKIPLFPAAEQTAERLAETPEFKQATNI 57
Query: 83 KVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEG-ETGPAAIRKAVSRN--G 139
KVN D QE V++ L+ KTL+V + +++LP E P ++ + + G
Sbjct: 58 KVNIDMAQEAVKLQVLKANKTLFVAPSQKSDYLYAKIKLPSSVEEVPLVQQRRIVKMLAG 117
Query: 140 METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
+TY + +GI+ T LD+VV+G VAVS+ G RIGKG GY DLE +++ + I P TV+
Sbjct: 118 EDTY-EELGIDQTEPLDMVVVGCVAVSERGQRIGKGNGYVDLEIAILVQLGVITPKTVIA 176
Query: 200 TTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQ-RMSQRPTGILWHLLSNRRLQLM 258
TTV D QVF L A+LF P+D +D+IVTPT+VI + R R G+ W LLS+RRL ++
Sbjct: 177 TTVADEQVFSELQADLFQPYDFTVDLIVTPTRVIRVEPRPEPRAIGV-WGLLSSRRLDVV 235
Query: 259 PILGQLRD 266
+L +L++
Sbjct: 236 RVLKKLKE 243
>UniRef50_Q8TUZ6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanopyrus kandleri|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Methanopyrus kandleri
Length = 237
Score = 162 bits (393), Expect = 1e-38
Identities = 94/218 (43%), Positives = 122/218 (55%), Gaps = 10/218 (4%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
K R VW LE +G A P PV RIPNFKGA AA +L ++ A VKVNPD P
Sbjct: 6 KARIRRMVWEELEESGEAAPPFPVEGRIPNFKGALVAARRLTSTPEYEEAEVVKVNPDSP 65
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGI 149
Q PVR L K L +P PRL+ GFL P R+A + G G+
Sbjct: 66 QRPVRERALRDGKILIMPTPRLKRGFL-------VVKNPKDPRRASTIRGAFQEGELTMP 118
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
++ ++DLVV GSVAV+ +G R+GKG GY DLE+G++ + + DT + TTVHD QV
Sbjct: 119 DELPAVDLVVAGSVAVAPDGARVGKGGGYFDLEWGILAQLDLVDEDTPIHTTVHDIQVLP 178
Query: 210 TLPAEL-FGPHDVPIDIIVTPTQVIETQRMSQRPTGIL 246
P E+ HDVP+D+I TPT E R ++P G+L
Sbjct: 179 --PGEIPMEEHDVPVDVIHTPTGTTECVRRYEKPGGLL 214
>UniRef50_UPI00015BAEF9 Cluster: 5-formyltetrahydrofolate
cyclo-ligase; n=1; Ignicoccus hospitalis KIN4/I|Rep:
5-formyltetrahydrofolate cyclo-ligase - Ignicoccus
hospitalis KIN4/I
Length = 250
Score = 160 bits (388), Expect = 4e-38
Identities = 92/241 (38%), Positives = 137/241 (56%), Gaps = 9/241 (3%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
K+ R +W L+ L FP + RIPNFKGA+EAA +L L +A VK NPD P
Sbjct: 8 KEKIRELIWNTLKPYALPPFP--IRGRIPNFKGAREAAERLRGLRERASAEVVKANPDSP 65
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFL--NRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
Q R+ LE+ K L + PRL+ GFL + E+P + A+ + + G +
Sbjct: 66 QRWARLAALEEGKVLIMATPRLREGFLLIDPNEVPREKFKEASTIRGAFKWGRKLKTVDD 125
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
+ + +D VV GSVAV EG R+GKG GYGDLEFG++ + + + + TTVHD QV
Sbjct: 126 LLNNVKRVDFVVEGSVAVDLEGRRVGKGAGYGDLEFGILTELGLMDVNVPIATTVHDVQV 185
Query: 208 FD-TLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLRD 266
+ LP + P DVP+ TPT++++ + + RP G+LW L R+L+ +P+L +L+
Sbjct: 186 LEGPLPQD---PWDVPLTFASTPTRLLKFKPL-PRPRGVLWEALDERKLEEIPLLKELKG 241
Query: 267 I 267
+
Sbjct: 242 L 242
>UniRef50_Q2JBX8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Actinomycetales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Frankia sp. (strain CcI3)
Length = 262
Score = 159 bits (387), Expect = 5e-38
Identities = 97/241 (40%), Positives = 132/241 (54%), Gaps = 17/241 (7%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
KQ R ++W LE G P V+ IP F GA+ AA +LA L + +A+ VK PD+
Sbjct: 9 KQQVRDRIWALLE--GEQAAPPGVHGYIPAFTGAEVAATRLAALPAWTSAHVVKAVPDRA 66
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAI----RKAVSRNGMETYGK 145
Q+PVR L KT+Y+ VPRL LP PA + +A R+ T
Sbjct: 67 QQPVRAHALRDGKTVYMAVPRLAE------PLPFYRLDPAVLPLPPEQAADRHVAATIAD 120
Query: 146 PIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
P+G++D +D+VV GSVAV++ G R+GKG GY DLEF L+ I+ T++VTTVHD
Sbjct: 121 PVGVDDMDPVDIVVCGSVAVNRAGVRLGKGAGYSDLEFALLQEAGLIQSTTIIVTTVHDL 180
Query: 206 QVF-DTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
QV D LP HD +D+IVTPT+ I T RP G+ W L + + +P+L
Sbjct: 181 QVVDDDLPET---RHDFSVDLIVTPTRTI-TCGPPHRPEGLYWQDLDDVTVSTIPVLAAR 236
Query: 265 R 265
R
Sbjct: 237 R 237
>UniRef50_A1RWD1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Thermofilum pendens Hrk 5|Rep:
5-formyltetrahydrofolate cyclo-ligase - Thermofilum
pendens (strain Hrk 5)
Length = 243
Score = 157 bits (380), Expect = 4e-37
Identities = 89/235 (37%), Positives = 133/235 (56%), Gaps = 6/235 (2%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
K R VW LE +A+ PRP Y +IP+F G A +L + DV++NA V PD
Sbjct: 12 KAELRRSVWSKLERMEVAISPRPCYGKIPSFVGIHSATQRLIKTDVYRNARVVYSTPDTS 71
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGI 149
+R L + KTL V +P L+ G++ + P+ E P +R A S G T G I +
Sbjct: 72 TRLLREETLRRGKTLVVSIPGLK-GYV--IVRPD-ELEPGDVRLASSVKGAVTKGDRITL 127
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
+ + +DLVV+GSVAV+ +G R+G+G G DLE+ L+ M A+ T V T VHD Q+ +
Sbjct: 128 LEGLKIDLVVLGSVAVNTDGARLGRGDGMHDLEYALLREMYAVAESTPVATLVHDLQILE 187
Query: 210 TLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
P + HDVPID I +P ++I +R ++P G++W +L ++ PIL +L
Sbjct: 188 E-PIPML-MHDVPIDYIASPYRLITVERKHRKPPGVIWEMLPIDFIKSTPILRRL 240
>UniRef50_A7D5P9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
5-formyltetrahydrofolate cyclo-ligase - Halorubrum
lacusprofundi ATCC 49239
Length = 294
Score = 124 bits (300), Expect = 2e-27
Identities = 71/177 (40%), Positives = 98/177 (55%), Gaps = 14/177 (7%)
Query: 30 KQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKP 89
KQ+ R VW E G A FP P ++RIPNF GA A +L + D + +A+T+K NPD P
Sbjct: 3 KQAVRETVWDAFEERGEARFPFPPHDRIPNFAGADAACDRLTDTDAWASASTLKCNPDAP 62
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTG--FLN------------RLELPEGETGPAAIRKAV 135
Q PVR L KT+YV PRL+ FL E + + + A
Sbjct: 63 QLPVRRAALRDGKTVYVAQPRLRDADPFLRIDPADLVDVGSVDSESADVDADGPTVDDAT 122
Query: 136 SRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAI 192
+ +G+ T+G P+ ED +DLVV GSV V+ +G RIGKG GY DLE+G++ + A+
Sbjct: 123 TVSGISTHGTPVAPEDVPHVDLVVAGSVGVTTDGARIGKGEGYSDLEWGVLSELGAV 179
Score = 60.1 bits (139), Expect = 6e-08
Identities = 35/82 (42%), Positives = 46/82 (56%), Gaps = 11/82 (13%)
Query: 193 KPD---TVVVTTVHDCQVFD------TLPAELFGP--HDVPIDIIVTPTQVIETQRMSQR 241
KPD T V TTVH+ V D PAEL P HDVP+D++VTP + I T+ R
Sbjct: 207 KPDDGATTVATTVHELSVLDGPESPIADPAELPAPDAHDVPLDLVVTPERTIRTETPYAR 266
Query: 242 PTGILWHLLSNRRLQLMPILGQ 263
P GI W L + +L +P+L +
Sbjct: 267 PEGIDWDALDDDKLAAIPVLAE 288
>UniRef50_O26306 Cluster: Conserved protein; n=1;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
Conserved protein - Methanobacterium thermoautotrophicum
Length = 338
Score = 118 bits (284), Expect = 2e-25
Identities = 75/197 (38%), Positives = 107/197 (54%), Gaps = 14/197 (7%)
Query: 37 VWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVI 96
+W L G++ P + RIP+FKG+ +AA +L+ ++ A V +PD Q PVR +
Sbjct: 144 IWDLLVEKGVSKRP---HGRIPDFKGSFDAAKRLSRTVEWERAGVVFCSPDSAQSPVRRL 200
Query: 97 CLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLD 156
LE K L +P P+++ G+L L G+ A + G YG PI + +D
Sbjct: 201 VLEAGKDLIMPTPKIKDGYL----LIGGDVPDAEAASTIG--GAYMYGSPI--REFPQVD 252
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
LVV GSVAV +G R+GKG GYGD E + AI DT + TTV + Q+ +P E
Sbjct: 253 LVVEGSVAVDLQGNRLGKGGGYGDREISELRGQGAIDEDTPLATTVDELQIIRRVPVE-- 310
Query: 217 GPHDVPIDIIVTPTQVI 233
HD I++IVTP +VI
Sbjct: 311 -EHDEMINMIVTPLRVI 326
>UniRef50_A6X384 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Ochrobactrum anthropi ATCC 49188|Rep:
5-formyltetrahydrofolate cyclo-ligase - Ochrobactrum
anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 245
Score = 108 bits (260), Expect = 1e-22
Identities = 64/211 (30%), Positives = 106/211 (50%), Gaps = 8/211 (3%)
Query: 57 IPNFKGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFL 116
IP+F+G + A +L ++ A V V PD +R + +P +Q GFL
Sbjct: 33 IPDFEGVEAATDRLLAIEGIAKAKLVFVTPDNSMIELRRRLIMSGTPFIMPTYGMQRGFL 92
Query: 117 NRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSL---DLVVMGSVAVSKEGYRIG 173
L G P + A +GME +G+ + +ED + D++ G+ AVS +G R G
Sbjct: 93 L---LEPGSVPPGLEKAAAWLDGMEHFGRSVSLEDLTHIGRFDVIATGASAVSIDGVRFG 149
Query: 174 KGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
KG + DLE+G+ + +++V VHD Q+ + +D+ +D I TP+++I
Sbjct: 150 KGHAFFDLEWGMFTDLGLADEQSLIVAAVHDVQIVE--ERLNVSENDIALDFIATPSRLI 207
Query: 234 ETQRMSQRPTGILWHLLSNRRLQLMPILGQL 264
E R +RP GI W+ +S +Q +P L +L
Sbjct: 208 EITRNRRRPRGIRWNDVSAEEIQSIPPLREL 238
>UniRef50_A6X380 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Ochrobactrum anthropi ATCC 49188|Rep:
5-formyltetrahydrofolate cyclo-ligase - Ochrobactrum
anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 246
Score = 106 bits (254), Expect = 7e-22
Identities = 70/242 (28%), Positives = 121/242 (50%), Gaps = 12/242 (4%)
Query: 30 KQSYRVKVWRHLETNGL--AVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPD 87
K S R +VW L + + F I +F+G ++A A+L ++NA+ + + PD
Sbjct: 7 KASVRERVWSELRKVAVPDSRFHFDFGEFIADFEGGEDAVARLTSHHYYQNADFIFITPD 66
Query: 88 KPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
+ +R+ L+ KT+ + ++ GF L P A + +GME G+P+
Sbjct: 67 NCLDRLRLQALKDGKTVLITTYSIKRGFW---VLDPKLISPDYYLYASTLDGMERVGQPV 123
Query: 148 GIEDTVSL---DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
++D ++ D +V G+ A++ EG R GKG G+ D E+G++ + I T VHD
Sbjct: 124 TLKDISAMPVVDYMVTGTGAINLEGVRFGKGHGFFDAEWGMLYRLGRITAATPAAAVVHD 183
Query: 205 CQVF-DTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQ 263
CQV + L +++ D D+I TPT+ IE + + GI+W L + +P L +
Sbjct: 184 CQVLSEKLTPDVY---DTVADVIFTPTRTIEVKDPHKPTCGIIWDRLDPVMYETIPPLQE 240
Query: 264 LR 265
L+
Sbjct: 241 LK 242
>UniRef50_A0LFH5 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-like; n=1; Syntrophobacter fumaroxidans
MPOB|Rep: 5-formyltetrahydrofolate cyclo-ligase-like -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 238
Score = 82.2 bits (194), Expect = 1e-14
Identities = 58/199 (29%), Positives = 98/199 (49%), Gaps = 9/199 (4%)
Query: 61 KGAQ-EAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRL 119
+GAQ +AA +L L ++ A +V ++P VR+ L +K L +P P L GF+
Sbjct: 33 EGAQGKAAERLRHLPRYREAQSVMISPVSSLYQVRLNALTDRKRLVMPTPGLHKGFV--- 89
Query: 120 ELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVS--LDLVVMGSVAVSKEGYRIGKGRG 177
+ G P AV + + + +DL+V + V ++G R+G G G
Sbjct: 90 VVEPGFIPPRQRHSAVQPGPENPFATRMPYREPPGFLIDLIVTEGLMVGRDGGRLGDGSG 149
Query: 178 YGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
+ DL+ ++ + + P VV V DC+V ++P + P DV I IVTP+++ T
Sbjct: 150 HLDLQCAILSSLGWLHPAFEVVGLVEDCRVVPSVPMK---PGDVEIHWIVTPSRMERTPA 206
Query: 238 MSQRPTGILWHLLSNRRLQ 256
+Q GI W LS ++++
Sbjct: 207 TAQARIGIQWDRLSLKQIK 225
>UniRef50_Q16IS3 Cluster: Putative uncharacterized protein; n=3;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 710
Score = 81.8 bits (193), Expect = 2e-14
Identities = 47/138 (34%), Positives = 73/138 (52%)
Query: 131 IRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMK 190
++K + G + + I LD VV+GS AV + G + Y D G ++
Sbjct: 491 LKKIIQLQGAGEPFQEMDIHRNEKLDTVVIGSCAVLRLGNHMDNINCYSDWGVGNSINRD 550
Query: 191 AIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLL 250
I DT V+TTVHD QV+DT P LF +D+ +D+IV T+V+ ++ R GI LL
Sbjct: 551 VIAKDTPVLTTVHDVQVYDTQPENLFNSYDLSLDLIVIWTEVVCQSKLMPRSAGIELKLL 610
Query: 251 SNRRLQLMPILGQLRDIE 268
S+R L ++ L +++ E
Sbjct: 611 SSRCLVIVQALNCIKEFE 628
>UniRef50_Q0V4P7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 304
Score = 78.2 bits (184), Expect = 2e-13
Identities = 57/223 (25%), Positives = 111/223 (49%), Gaps = 14/223 (6%)
Query: 59 NFKGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNR 118
+F+G+ A ++ E + +K+A TV + D E +R L+ K + V RL+ GF+
Sbjct: 42 DFRGSAAAVDRVREQNCYKDARTVLITCDNSLEGLRHQALQDGKKVLVGTYRLRRGFVL- 100
Query: 119 LELPEGETGPAAIRKAVSRNGMET--YGKPIGI----EDTVSLDLVVMGSVAVSKEGYRI 172
L A +R A +GME G+ + + ++ + +D+ VMG + +++G +
Sbjct: 101 --LDPSRIDGADLRLAACLDGMEKPGLGRAVSLMQLRDEGLHIDMCVMGGLVFNQDGVVL 158
Query: 173 GKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD--TLPAELFGPH---DVPIDIIV 227
+G+ ++++ L+ +K + T V+ VH CQV D ++ E P+ +V D+I+
Sbjct: 159 HEGQALFEVQWALLQDIKILANTTPVIAVVHACQVVDEVSMGMEKTSPNKPGEVQCDLII 218
Query: 228 TPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLRDIEML 270
TP + E + + +GI + + L + L +LR I +
Sbjct: 219 TPDRTFEIEAAVKSASGIDFDNVDAEALNNIQPLQELRGIRSM 261
>UniRef50_A7ERE4 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 161
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/133 (33%), Positives = 70/133 (52%), Gaps = 8/133 (6%)
Query: 140 METYGKPIGIEDT----VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPD 195
ME YG+PI + + + + L+V G+ A++ +G R GKGRG+ DL +G++ + A+ D
Sbjct: 1 MERYGRPITLTEIRGEGLRISLMVTGTGAINYKGLRFGKGRGFFDLAWGMLYSIGAVNKD 60
Query: 196 TVVVTTVHDCQVFDTLPAELFGPH-DVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRR 254
T VH+CQV D E G D IVT +VI ++ GI+W L
Sbjct: 61 THTAALVHECQVLD---EEFKGEQWDTGCQFIVTNKRVITVSGAAKPGYGIIWDKLQKGM 117
Query: 255 LQLMPILGQLRDI 267
+ + L +L++I
Sbjct: 118 MDDIESLRELQNI 130
>UniRef50_Q5SLW0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Thermus thermophilus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579)
Length = 187
Score = 72.1 bits (169), Expect = 1e-11
Identities = 58/206 (28%), Positives = 94/206 (45%), Gaps = 22/206 (10%)
Query: 28 VTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPD 87
+T R +VW L LA+ P P + PNF GA+ AA +L + F+ A V D
Sbjct: 1 MTLGELREEVWNALARYDLALHPTPPHGHHPNFLGARRAAERLLKTPEFQGARRVLAGMD 60
Query: 88 KPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
+P+R L Q K L +P P FL ++ + +R+A +G +
Sbjct: 61 AVLKPLREEALRQGKELLLPHPDRPGEFLLLRDVDPRKL--KRVREAY------RFGVRV 112
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
+E+ DLV++G+VAV +EG +GKG G+ ++ + T H V
Sbjct: 113 ALEEATP-DLVLIGAVAVDEEGGWVGKGYGF---------PQSWLRVEAPFATLAHPVMV 162
Query: 208 FDTLPAELFGPHDVPIDIIVTPTQVI 233
+ LP P + +D+I TP +++
Sbjct: 163 YPRLPV----PPERRVDLIATPQRLL 184
>UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 214
Score = 58.0 bits (134), Expect = 2e-07
Identities = 39/111 (35%), Positives = 60/111 (54%), Gaps = 13/111 (11%)
Query: 125 ETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFG 184
E G A + + R + G+ +G E DL+V+ ++A S +G R+G+G G+ D
Sbjct: 110 EPGQALV--TLGRPPAQPSGEVLGAESLKEADLIVIPALAASADGTRLGQGGGWYD---R 164
Query: 185 LMMHMKAIKPDTVVVTTVHDCQVFDT--LPAELFGPHDVPIDIIVTPTQVI 233
+ H P T VV + D +V + +PAE PHDVP+D IVTPT+ +
Sbjct: 165 ALTHR---SPGTPVVAVIFDDEVLEAEIIPAE---PHDVPVDGIVTPTRTM 209
>UniRef50_A1G3P7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Salinispora|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Salinispora arenicola CNS205
Length = 209
Score = 54.4 bits (125), Expect = 3e-06
Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 10/106 (9%)
Query: 126 TGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGL 185
TGP + A R E P+G + DLVV+ +VAV + G R+G+G G D
Sbjct: 103 TGPDDL-VASGRGMREPTWPPLGKSAVAAADLVVLPAVAVDRRGVRLGRGGGSYD----- 156
Query: 186 MMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQ 231
+ + T+ V +H+ ++ D LP E PHD P+ ++TP +
Sbjct: 157 -RALARVPATTLTVVPLHEGELVDVLPRE---PHDRPVRAVITPAE 198
>UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Thiobacillus denitrificans ATCC
25259|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Thiobacillus denitrificans (strain ATCC 25259)
Length = 199
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/74 (36%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDL++M V +GYR+G G GY D M H + + +V ++CQ DTLP +
Sbjct: 115 LDLLLMPLVGFDTDGYRLGMGGGYYDATLAFMQHRRHWRKPR-LVGVAYECQRVDTLPHD 173
Query: 215 LFGPHDVPIDIIVT 228
P D+P+D ++T
Sbjct: 174 ---PWDMPLDAVLT 184
>UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Thermus thermophilus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length = 184
Score = 51.2 bits (117), Expect = 3e-05
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 11/97 (11%)
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
ED LDLVV+ +A +EGYR+G G+G+ D +K ++ TV V V +F
Sbjct: 98 EDPRVLDLVVVPGLAFDREGYRLGHGQGFYD------RFLKEVRAATVGV--VPQALLFP 149
Query: 210 TLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGIL 246
LP + P DVP+D + T V +R + P G+L
Sbjct: 150 ALPRD---PWDVPVDHLATEAGVEAVKRPAPGPGGLL 183
>UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Geobacillus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacillus kaustophilus
Length = 190
Score = 50.8 bits (116), Expect = 4e-05
Identities = 52/180 (28%), Positives = 78/180 (43%), Gaps = 24/180 (13%)
Query: 64 QEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQ----KTLYVPV--PRLQTGFLN 117
++ AA L +++ A T+ + + E + +EQ KT+ VP PR +T
Sbjct: 29 RQIAAHLYRWPLWQTARTIAMTVSRETEVNTLPIMEQAWREGKTIGVPKCDPRAKTMSFR 88
Query: 118 RLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRG 177
RLE A + KA + E K D DL+++ V +K GYRIG G G
Sbjct: 89 RLE------SFAQLEKAYA-GLFEPIEKQTTPIDRDEFDLIIVPGVCFAKTGYRIGYGGG 141
Query: 178 YGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
Y D ++ V + QV D +PAE HDVP+ I+T V+ +R
Sbjct: 142 YYD------RYLPG--ASAVTAALAYSFQVMDDIPAE---EHDVPVKFIITDQGVLHCER 190
>UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Blastopirellula marina DSM 3645|Rep:
5-formyltetrahydrofolate cyclo-ligase - Blastopirellula
marina DSM 3645
Length = 197
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 9/83 (10%)
Query: 153 VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
V +DL ++ VA G R+G G+GY D L+ M +P V +CQ+ +P
Sbjct: 120 VEIDLAILPGVAFDLHGNRLGYGKGYFD---RLLSEM---RPQAVTCALAFECQLTAQIP 173
Query: 213 AELFGPHDVPIDIIVTPTQVIET 235
E PHD+PID +VT ++I +
Sbjct: 174 TE---PHDLPIDYLVTEDRLIRS 193
>UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=2; Clostridium difficile|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Clostridium
difficile (strain 630)
Length = 189
Score = 49.6 bits (113), Expect = 8e-05
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D +LD+V++ +VA YR+G G G+ D ++ ++ D + + D Q+FD+
Sbjct: 112 DIKALDVVIVPAVAYDIHCYRLGYGGGFYD------RFLENLRKDAITIGIAFDFQIFDS 165
Query: 211 LPAELFGPHDVPIDIIVTPTQVI 233
+P E HD +D IVT T++I
Sbjct: 166 IPKE---THDAQLDYIVTETRII 185
>UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium beijerinckii NCIMB 8052|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
beijerinckii NCIMB 8052
Length = 196
Score = 49.6 bits (113), Expect = 8e-05
Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 21/144 (14%)
Query: 98 LEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI-GIEDTV--- 153
L K +YVP ++T ++ +E+ K++ +YG P I D
Sbjct: 69 LNNNKRIYVPRTEIKTRLMDAVEI-----------KSLDNLSESSYGIPEPSINDPYIDP 117
Query: 154 -SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
LDL+++ VA K G R+G G G+ D F ++ IK T + +D QV D +P
Sbjct: 118 NELDLIIVPGVAFDKRGGRVGYGAGFYDRYF-KKVNKDNIKRIT-KLALAYDFQVLDKVP 175
Query: 213 AELFGPHDVPIDIIVTPTQVIETQ 236
HDVP+D I+T + I+ +
Sbjct: 176 TSY---HDVPVDYIITEKEFIKLE 196
>UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-related protein; n=3; Actinobacteria
(class)|Rep: 5-formyltetrahydrofolate
cyclo-ligase-related protein - marine actinobacterium
PHSC20C1
Length = 196
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/88 (34%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 146 PIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
PI I D +DL+++ + +V + G R+G GRGY D G M KP + + +
Sbjct: 115 PIAIND---VDLIIVPAASVDRTGMRMGWGRGYFDKTLGSM----ETKPP--IYAVIFES 165
Query: 206 QVFDTLPAELFGPHDVPIDIIVTPTQVI 233
+ D +P EL HD P++ IVTP+ ++
Sbjct: 166 EYVDAVPTEL---HDQPVNGIVTPSGIV 190
>UniRef50_A6PRD6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
5-formyltetrahydrofolate cyclo-ligase - Victivallis
vadensis ATCC BAA-548
Length = 195
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 11/83 (13%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
L + +VA +K G R+G+G G+ D M A++P V+ ++ CQ+ + LP E
Sbjct: 121 LFLTPAVACTKAGVRLGRGGGFYD-----RMLAGAVRP---VIGVIYCCQLAEALPVEA- 171
Query: 217 GPHDVPIDIIVTPTQVIETQRMS 239
HD P++++VT +V+ET +S
Sbjct: 172 --HDRPVEVVVTEEEVVETTAVS 192
>UniRef50_Q47T07 Cluster: Putative uncharacterized protein; n=1;
Thermobifida fusca YX|Rep: Putative uncharacterized
protein - Thermobifida fusca (strain YX)
Length = 214
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 10/104 (9%)
Query: 126 TGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGL 185
TGP ++ A +E G +G + ++V ++A + GYR+G+G G D
Sbjct: 111 TGPESLAPA-GHGLLEPTGTRLGADAVAEARVLVCPALAADRAGYRLGRGAGCYD----- 164
Query: 186 MMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTP 229
+ A T+ + V+D ++ D +P E PHD P+ +VTP
Sbjct: 165 -RVLAAAGEQTLSLAVVYDDELVDAVPVE---PHDRPVRAVVTP 204
>UniRef50_A6WEB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Kineococcus radiotolerans SRS30216|Rep:
5-formyltetrahydrofolate cyclo-ligase - Kineococcus
radiotolerans SRS30216
Length = 208
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 7/93 (7%)
Query: 140 METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
++ + P+G + ++DLV++ ++AV G R+G+G G D G + A P V+
Sbjct: 116 LDRHPGPLGPDAIAAVDLVIVPALAVDTAGRRLGQGGGSYDRALG---RVPARVP---VL 169
Query: 200 TTVHDCQVFDTLPAEL-FGPHDVPIDIIVTPTQ 231
VHD ++FD L PHD P+ + TP++
Sbjct: 170 AVVHDDELFDAAVTPLPTLPHDRPVQAVATPSR 202
>UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Bacillus sp. B14905|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Bacillus sp. B14905
Length = 197
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/84 (34%), Positives = 48/84 (57%), Gaps = 10/84 (11%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D +D++++ V + GYRIG G GY D +++ K K +++ + D Q+ +
Sbjct: 113 DANEMDIILVPGVVFDRLGYRIGYGGGYYD---RYVLNYKKGK----LMSLLFDEQIVNR 165
Query: 211 LPAELFGPHDVPIDIIVTPTQVIE 234
+P E HD P+DIIVTPT+ I+
Sbjct: 166 VPTE---EHDCPVDIIVTPTERID 186
>UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 191
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/82 (32%), Positives = 44/82 (53%), Gaps = 9/82 (10%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D +DLVV+ VA +G RIG G GY D+ ++ ++ D + + D QVF +
Sbjct: 117 DPKDIDLVVVPGVAFDVKGGRIGYGAGYYDI------FLREVRKDCLKIGIAFDIQVFPS 170
Query: 211 LPAELFGPHDVPIDIIVTPTQV 232
+P E HD+ +D +VT ++
Sbjct: 171 IPKE---EHDILMDAVVTENEI 189
>UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Oceanobacter sp. RED65|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Oceanobacter sp. RED65
Length = 239
Score = 47.2 bits (107), Expect = 4e-04
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDLV M VA ++G R+G G G+ D F + H KP ++ H Q ++LP E
Sbjct: 164 LDLVFMPLVAFDQQGGRLGMGGGFYDRSFEFLRHSTLPKPK--LIGLAHSFQQVESLPIE 221
Query: 215 LFGPHDVPIDIIVTPTQVIE 234
+ DVP+ IVT +IE
Sbjct: 222 EW---DVPMHAIVTEKGLIE 238
>UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni
ACN14a|Rep: Putative ligase - Frankia alni (strain
ACN14a)
Length = 262
Score = 46.8 bits (106), Expect = 6e-04
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 9/86 (10%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D + D V++ ++AV + G R+G+G G D ++ + PD V+ ++D ++ D
Sbjct: 172 DLSAADAVIIPALAVDRAGRRLGRGGGSYDRA------LRRVAPDVPVIAVLYDQELLDL 225
Query: 211 LPAELFGPHDVPIDIIVTPTQVIETQ 236
+P E HD + IIVTP++ + +
Sbjct: 226 VPTE---EHDRSVKIIVTPSRTLRCE 248
>UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1;
Aquifex aeolicus|Rep: Putative uncharacterized protein -
Aquifex aeolicus
Length = 186
Score = 46.4 bits (105), Expect = 8e-04
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 14/89 (15%)
Query: 144 GKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVH 203
G+ + ED +D + + VA EGYR+G G+GY D L+ +K +K V +
Sbjct: 104 GERVNPED---VDFIAVPGVAFDLEGYRLGFGKGYYD---RLLKRVKGLK-----VGVAY 152
Query: 204 DCQVFDTLPAELFGPHDVPIDIIVTPTQV 232
QVF+ LP + + D+P+D++VT V
Sbjct: 153 SFQVFERLPRDAW---DIPVDVLVTEKNV 178
>UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-related protein; n=18; Mycobacterium|Rep:
5-formyltetrahydrofolate cyclo-ligase-related protein -
Mycobacterium tuberculosis
Length = 195
Score = 46.4 bits (105), Expect = 8e-04
Identities = 40/135 (29%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 96 ICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVS- 154
+ L + + +PV R G L L L GE + +A R G+ +P E ++
Sbjct: 62 VLLRRAGRVLLPVARTAGGDLP-LPLRWGEYRAGGLARA--RWGLLEPPEPWLPEAALAQ 118
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LV++ ++AV ++G R+G+GRG+ D ++ P +V V ++ D LP+E
Sbjct: 119 ASLVLVPALAVDRQGVRLGRGRGFYD------RSLRCRDPHARLVAVVRTVELVDVLPSE 172
Query: 215 LFGPHDVPIDIIVTP 229
PHDVP+ +TP
Sbjct: 173 ---PHDVPMTHALTP 184
>UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23;
Enterobacteriaceae|Rep: Uncharacterized protein ygfA -
Escherichia coli O157:H7
Length = 182
Score = 46.4 bits (105), Expect = 8e-04
Identities = 28/80 (35%), Positives = 42/80 (52%), Gaps = 8/80 (10%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+++ VA + G R+G G G+ D H K T V HDCQ+ + LP E
Sbjct: 110 LDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQHYK-----TQPVGYAHDCQLVEKLPVE 164
Query: 215 LFGPHDVPIDIIVTPTQVIE 234
+ D+P+ +VTP++V E
Sbjct: 165 EW---DIPLPAVVTPSKVWE 181
>UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Marinomonas|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Marinomonas sp. MWYL1
Length = 194
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+V++ V +G R+G G G+ D F K +++ HDCQ +LP E
Sbjct: 121 LDIVLLPLVGFDSKGGRLGMGGGFYDRTF----ENKRADQKPLLIGLAHDCQEVKSLPVE 176
Query: 215 LFGPHDVPIDIIVTPTQVIE 234
+ DVP+ I+TPT+ I+
Sbjct: 177 GW---DVPLQAIITPTKSIK 193
>UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 216
Score = 46.0 bits (104), Expect = 0.001
Identities = 45/179 (25%), Positives = 77/179 (43%), Gaps = 16/179 (8%)
Query: 63 AQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVI-----CLEQQKTLYVP------VPRL 111
+QE +L + +FKNA V + + P V+ + C Q+K +Y+P VP
Sbjct: 34 SQEILDRLVQSPIFKNAQKVALFMNMPDLEVKTLPIIQECYNQKKEVYLPRCNTISVPNR 93
Query: 112 QTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYR 171
+ +L+ L +P + +R +E + D+ LDL++M VA +++ R
Sbjct: 94 KRNYLSMLNVPTFQD-ILELRPQGKYQLLEPIEGKDAL-DSGDLDLILMPGVAFNQQRER 151
Query: 172 IGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPT 230
+G G G+ D P V + +P EL HD +D I+TP+
Sbjct: 152 LGHGAGFYDEYLYTYKTKWEHLPLLVGLALEEQITTNGLIPVEL---HDFKLDQIITPS 207
>UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=4; Staphylococcus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 183
Score = 45.6 bits (103), Expect = 0.001
Identities = 55/189 (29%), Positives = 84/189 (44%), Gaps = 31/189 (16%)
Query: 54 YNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPDKPQE----PVRVICLEQQKTLYVPVP 109
Y++ + + A KL + + ++ ANT+ P E P+ L K ++VP
Sbjct: 17 YDKEQKYLADEWLAKKLYQSEAYRKANTIGFVLSMPHEVNTYPIITHSLNNNKKIFVPET 76
Query: 110 RLQTG---FLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVS 166
Q F L + + E I ++S P+G T +DLVV+ VA
Sbjct: 77 NYQQQDMTFKQLLSIEDIEKDSKGIYHSIS---------PVGT--TNKMDLVVVPGVAFD 125
Query: 167 KEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPID-I 225
K GYRIG G GY D F L H K +T V+ ++D Q L PHD P++ +
Sbjct: 126 KLGYRIGYGGGYYD-RF-LSQH----KCNT--VSLLYDFQ----LAQFNIEPHDQPVEQL 173
Query: 226 IVTPTQVIE 234
I+ +V+E
Sbjct: 174 IIYHNKVVE 182
>UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 301
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/104 (31%), Positives = 51/104 (49%), Gaps = 10/104 (9%)
Query: 126 TGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGL 185
TGP ++ A +E G +G E D V++ ++AV + G R+G+G GY D
Sbjct: 199 TGPDSLEPA-GYGLLEPSGARLGPEAIGEADAVLVPALAVDRRGVRLGRGAGYYDRS--- 254
Query: 186 MMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTP 229
+ M A P +V V D + + LP E HDV + ++TP
Sbjct: 255 -LPMAA--PAAALVAVVRDEEFVEELPGE---DHDVRVGAVLTP 292
>UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Clostridiaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Alkaliphilus metalliredigens QYMF
Length = 192
Score = 45.2 bits (102), Expect = 0.002
Identities = 39/137 (28%), Positives = 63/137 (45%), Gaps = 13/137 (9%)
Query: 98 LEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDL 157
L+Q K +++PV +T L EL + + V E +P+ D LD
Sbjct: 64 LDQNKRVFIPVCVPKTKELIISELLDFDEDLEIGHFGVLEPKKEAL-RPV---DPKILDF 119
Query: 158 VVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFG 217
+++ +A +GYRIG G GY D + I V+ D V D++P + F
Sbjct: 120 IIVPGLAFDSQGYRIGYGGGYYD------RFLPKISDKVPKVSLAFDEFVIDSVPTDSF- 172
Query: 218 PHDVPIDIIVTPTQVIE 234
D+P+D I+T ++IE
Sbjct: 173 --DIPVDFIITEKKLIE 187
>UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 161
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/76 (30%), Positives = 43/76 (56%), Gaps = 5/76 (6%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTL 211
T LDL+++ + SKEG+R+G+G+GY D+ + +KP T+ + Q+ +++
Sbjct: 85 TGGLDLIIIPGLGFSKEGHRLGRGKGYYDIYQNRCVEETGVKPVTIALAFKE--QICESI 142
Query: 212 PAELFGPHDVPIDIIV 227
P +DV ID ++
Sbjct: 143 P---ITENDVTIDYVL 155
>UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Rubrobacter xylanophilus DSM 9941|Rep:
5-formyltetrahydrofolate cyclo-ligase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 196
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/91 (30%), Positives = 48/91 (52%), Gaps = 12/91 (13%)
Query: 147 IGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQ 206
+G+E+ ++ V++ VA + G R+G G GY D G + + P +V + Q
Sbjct: 117 VGLEE---VEFVLVPGVAFDRRGGRLGHGAGYYDRLLG---GARRLPP---LVAAAFEAQ 167
Query: 207 VFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
+ + +P E PHDVP+D++VT V +R
Sbjct: 168 IVERVPME---PHDVPVDLVVTERGVWRRER 195
>UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Anaeromyxobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Anaeromyxobacter sp. Fw109-5
Length = 205
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 10/87 (11%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
++D V+M VA S +G+R+G+G GY D M P V D Q+ LPA
Sbjct: 129 AVDCVLMPGVAFSPDGHRLGRGGGYYDATLEAM-------PRAARVGLAFDLQLVPALPA 181
Query: 214 ELFGPHDVPIDIIVTPTQVIETQRMSQ 240
E HD +D +VT +V+ +R S+
Sbjct: 182 E---GHDARLDALVTEARVLLFRRESR 205
>UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=10; Gammaproteobacteria|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Aeromonas salmonicida (strain A449)
Length = 202
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 6/78 (7%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
+LDL+ VA EG R+G G GY D H + P + + HDCQ D +P
Sbjct: 126 TLDLICTPLVAFDAEGNRLGMGGGYYDRTLA-CWHEHKLGPKPLGL--AHDCQQVDAVPQ 182
Query: 214 ELFGPHDVPIDIIVTPTQ 231
E + DVP+ I+TP++
Sbjct: 183 EQW---DVPLPQIITPSR 197
>UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=5; Vibrio|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Vibrio vulnificus
Length = 199
Score = 44.4 bits (100), Expect = 0.003
Identities = 31/80 (38%), Positives = 42/80 (52%), Gaps = 10/80 (12%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGD--LEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
LDL+ VA G R+G G GY D LE + A KP + HDCQ + LP
Sbjct: 121 LDLICTPLVAFDSTGQRLGMGGGYYDRTLERWFRTGLGA-KP----IGIAHDCQHVEQLP 175
Query: 213 AELFGPHDVPIDIIVTPTQV 232
E++ D+P+ IVTP+Q+
Sbjct: 176 CEVW---DIPLPKIVTPSQI 192
>UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=3; Coxiella burnetii|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Coxiella burnetii
Length = 197
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTL 211
T LDL+ + VA K+G R+G+G GY D + A KP + V ++ Q +++
Sbjct: 119 TKELDLIFLPLVAFDKDGNRLGRGAGYYDRALAFLKDSNAQKPKLIGV--AYEFQKINSI 176
Query: 212 PAELFGPHDVPIDIIVTPTQV 232
AE + D+P++ +VT +
Sbjct: 177 TAEKW---DIPLNSVVTEKNI 194
>UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pirellula sp.|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Rhodopirellula baltica
Length = 205
Score = 44.4 bits (100), Expect = 0.003
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 9/78 (11%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+V++ VA + G R+G G+GY D G ++ DT ++ +CQ+ +P +
Sbjct: 129 LDVVLVPGVAFDRHGGRVGHGKGYYDKLLG------NVRSDTRLIGLAFECQMVGAVPVQ 182
Query: 215 LFGPHDVPIDIIVTPTQV 232
HD+ +D++VT V
Sbjct: 183 ---AHDIRMDMVVTEDHV 197
>UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
putative; n=1; Pelodictyon luteolum DSM 273|Rep:
5-formyltetrahydrofolate cyclo-ligase, putative -
Pelodictyon luteolum (strain DSM 273) (Chlorobium
luteolum (strain DSM273))
Length = 213
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 10/94 (10%)
Query: 143 YGKPIGIE----DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVV 198
+G P +E D +D VV+ VAV + GYR+G G+G+ D + HM ++P +
Sbjct: 113 FGSPEPLERSLGDEYMIDAVVVPLVAVDRSGYRLGYGKGFYDRFLARLQHM-GVRPCRIG 171
Query: 199 VTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQV 232
Q+ D LP + P D P+D+ V V
Sbjct: 172 FG--FSMQLHDRLPCD---PWDEPLDLFVDENAV 200
>UniRef50_Q4FR52 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=3; Psychrobacter|Rep: Possible
5-formyltetrahydrofolate cyclo-ligase - Psychrobacter
arcticum
Length = 230
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/76 (34%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+++ AV K G R+G G G+ D G A KP + + +D QV + L +
Sbjct: 155 LDVIICPLTAVDKNGNRMGMGSGFYDTTLGKSYQAGAKKP--LKIGWCYDFQVVEQLDRQ 212
Query: 215 LFGPHDVPIDIIVTPT 230
P DVP+D ++TP+
Sbjct: 213 ---PWDVPLDGLITPS 225
>UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Frankia|Rep: 5-formyltetrahydrofolate cyclo-ligase
- Frankia sp. (strain CcI3)
Length = 259
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/81 (29%), Positives = 44/81 (54%), Gaps = 9/81 (11%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
D+V++ ++AV + G R+G+G G D + + D V+ +HD +V D +P E
Sbjct: 174 DVVIIPALAVDRTGRRLGRGGGSYD------RVLARVGADVPVIAVLHDQEVLDEIPME- 226
Query: 216 FGPHDVPIDIIVTPTQVIETQ 236
HD + II+TP++ + +
Sbjct: 227 --SHDHNVKIIITPSRTLRCE 245
>UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Carboxydothermus hydrogenoformans
Z-2901|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Carboxydothermus hydrogenoformans (strain
Z-2901 / DSM 6008)
Length = 192
Score = 43.2 bits (97), Expect = 0.007
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 9/79 (11%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+DLV++ VA +G R+G G G+ D + ++P V + Q+ +P
Sbjct: 118 IDLVLVPGVAFDLKGNRLGYGAGFYD------RFLPNLQPAVKKVALAFELQIVPKIPT- 170
Query: 215 LFGPHDVPIDIIVTPTQVI 233
GPHD+P+D I+T ++I
Sbjct: 171 --GPHDIPMDYIITEERII 187
>UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=10; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Shewanella sp. (strain MR-7)
Length = 228
Score = 43.2 bits (97), Expect = 0.007
Identities = 30/77 (38%), Positives = 41/77 (53%), Gaps = 7/77 (9%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+D+VV VA +G R+G G GY D H K KP + + HDCQ TLP E
Sbjct: 155 IDVVVTPLVAFDIKGNRMGMGGGYYDRTLA-NWHAKG-KP--LPMGYAHDCQQVTTLPCE 210
Query: 215 LFGPHDVPIDIIVTPTQ 231
+ DVP+ I+TP++
Sbjct: 211 HW---DVPLPAIITPSR 224
>UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Shewanella amazonensis SB2B|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length = 228
Score = 43.2 bits (97), Expect = 0.007
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 11/79 (13%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPD-TVVVTTVHDCQVFDTLPA 213
LD ++ VA G R+G G G+ D + PD T V+ HDCQ LP
Sbjct: 153 LDAIITPLVAFDDSGNRLGMGGGFYDRTLAQL-------PDSTRVIGLAHDCQRLPALPV 205
Query: 214 ELFGPHDVPIDIIVTPTQV 232
E + DVP+ IVTP+++
Sbjct: 206 EAW---DVPLTTIVTPSRI 221
>UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Corynebacterium|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Corynebacterium glutamicum
(Brevibacterium flavum)
Length = 190
Score = 42.7 bits (96), Expect = 0.010
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Query: 141 ETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVT 200
E G +G E DLV+ ++A + G R+GKG G+ D +K D V+T
Sbjct: 104 EPGGTRLGPEALNFCDLVIAPALACTPSGIRLGKGGGFYDRALA-----TGVKAD--VIT 156
Query: 201 TVHDCQVFDTLPAELFGPHDVPIDIIVTPTQV 232
+ + ++ D + E HD+P+++I+TP V
Sbjct: 157 LLFNGEIRDDIEVE---EHDLPVNVIITPAGV 185
>UniRef50_Q1NLL0 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=1; delta proteobacterium MLMS-1|Rep:
Putative 5-formyltetrahydrofolate cyclo-ligase - delta
proteobacterium MLMS-1
Length = 230
Score = 42.7 bits (96), Expect = 0.010
Identities = 39/168 (23%), Positives = 68/168 (40%), Gaps = 9/168 (5%)
Query: 65 EAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEG 124
+ A L D ++ + + V P +R+ L K L +P P L+ GF L P
Sbjct: 29 QLAQTLRRQDFYRRSRRLLVGPGDLLSQLRINALLDGKELLMPAPGLRDGFY--LLRPYS 86
Query: 125 ETGPAAIRKAVSRNGMETYGKPIGIEDTVSLD---LVVMGSVAVSKEGYRIGKGRGYGDL 181
P + AVS G+ +G+ + LD L+ +A G+ + +G+G+ DL
Sbjct: 87 IAFP-DLPHAVSYKGLSRFGRRLPTAKLAGLDIELLIDQALLADPASGWLLDEGQGFFDL 145
Query: 182 EFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTP 229
++ A+ + VV P + P D+ D ++ P
Sbjct: 146 SLAILATAGALAVEHRVVAVPAALAAGSRWPVD---PWDIRADYLLVP 190
>UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Treponema denticola|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Treponema denticola
Length = 229
Score = 42.3 bits (95), Expect = 0.013
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 6/77 (7%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTV-HDCQVFDTLPAEL 215
L+++ A SK+G R+G+G G+ D F + K+IK + V + + Q+ DT+P
Sbjct: 153 LILVPGRAFSKKGERMGRGGGFYDRFFEKL--FKSIKKEEVCLAGLCFSGQILDTIP--- 207
Query: 216 FGPHDVPIDIIVTPTQV 232
G D P+D++VT +V
Sbjct: 208 MGEFDHPVDLVVTEAEV 224
>UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Prosthecochloris aestuarii DSM 271|Rep:
5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
aestuarii DSM 271
Length = 197
Score = 42.3 bits (95), Expect = 0.013
Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 153 VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
V D++++ VA + G RIG G G D F + + P V + QV DTLP
Sbjct: 120 VVADVIIVPLVAADRSGTRIGYGAGCYD-RFFAALQKRGFTPHAVGI--CFSFQVLDTLP 176
Query: 213 AELFGPHDVPIDIIVTPTQVIETQ 236
F P D +D IVT +VI Q
Sbjct: 177 ---FDPWDRKLDCIVTEQEVISIQ 197
>UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=25; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Enterobacter sp. 638
Length = 198
Score = 42.3 bits (95), Expect = 0.013
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 8/80 (10%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+++ VA + G R+G G G+ D ++P V HDCQ D LP E
Sbjct: 126 LDVLITPLVAFDRYGQRLGMGGGFYDRTL-QNWQQHGLQP----VGYAHDCQGVDMLPVE 180
Query: 215 LFGPHDVPIDIIVTPTQVIE 234
+ D+P+ +VTP++V E
Sbjct: 181 KW---DIPLPAVVTPSKVWE 197
>UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Desulfuromonadales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacter lovleyi SZ
Length = 197
Score = 42.3 bits (95), Expect = 0.013
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 9/78 (11%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
DL+V+ VA +G+RIG G+GY D + ++ V+V HD Q+ + +PAE
Sbjct: 115 DLIVVPGVAFDLQGHRIGFGKGYYD------RCLSQLQRHGVLVGLCHDFQLLERIPAE- 167
Query: 216 FGPHDVPIDIIVTPTQVI 233
HD+ + I+T ++I
Sbjct: 168 --GHDIRMQHIITDKRLI 183
>UniRef50_A0LR79 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Acidothermus cellulolyticus 11B|Rep:
5-formyltetrahydrofolate cyclo-ligase - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 202
Score = 42.3 bits (95), Expect = 0.013
Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 9/90 (10%)
Query: 142 TYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
T + +G+E + DL+V+ ++AV G R+G+G G G ++ P ++ V
Sbjct: 112 TQPRALGVEAVSTADLIVVPALAVDPTGVRLGRGGG------GYDRALRRRSPGSLTVAV 165
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQ 231
++D ++ +LP HD +D +TP++
Sbjct: 166 IYDDELVPSLPE---ADHDQRVDAALTPSR 192
>UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate
cyclo-ligase; n=1; Chromobacterium violaceum|Rep:
Probable 5-formyltetrahydrofolate cyclo-ligase -
Chromobacterium violaceum
Length = 203
Score = 41.9 bits (94), Expect = 0.017
Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+V + + V ++GYR+G+G G+ D A+ ++V DCQ+ D +P E
Sbjct: 120 LDVVFVPLLGVDRDGYRMGQGGGFYDSTLA-FRRRHALSGKPLLVGVAFDCQLVDAVPRE 178
Query: 215 LFGPHDVPIDIIVT 228
+ DV +D ++T
Sbjct: 179 AW---DVRLDWLLT 189
>UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Chlorobium phaeobacteroides BS1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
phaeobacteroides BS1
Length = 194
Score = 41.9 bits (94), Expect = 0.017
Identities = 30/95 (31%), Positives = 49/95 (51%), Gaps = 10/95 (10%)
Query: 143 YGKPIGIEDT----VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVV 198
+G+P + D V D+V++ VAV +EG R+G G+GY D F + ++ P T+
Sbjct: 104 FGQPEPVSDNGCADVLPDVVILPVVAVDREGRRLGYGKGYYD-RFIAGLRLQGATPFTLA 162
Query: 199 VTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
V Q+ +P + P D ID +VT +V+
Sbjct: 163 V--AFSFQLVSHVPED---PWDEKIDCVVTEKEVV 192
>UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Halothermothrix orenii H 168|Rep:
5-formyltetrahydrofolate cyclo-ligase - Halothermothrix
orenii H 168
Length = 193
Score = 41.9 bits (94), Expect = 0.017
Identities = 26/82 (31%), Positives = 45/82 (54%), Gaps = 11/82 (13%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVV-VTTVHDCQVFDTLPA 213
LD+V++ + S++GYRIG G GY D F + + PD V+ V + + D LP
Sbjct: 117 LDIVIVPGIVFSRDGYRIGYGGGYYD-RFLVKL------PDNVLTVGFTYHALLLDNLPI 169
Query: 214 ELFGPHDVPIDIIVTPTQVIET 235
+ + D P+D+++T + + T
Sbjct: 170 DRY---DQPVDMVITERETLVT 188
>UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1;
Bifidobacterium longum|Rep: Putative uncharacterized
protein - Bifidobacterium longum
Length = 249
Score = 41.5 bits (93), Expect = 0.022
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 10/90 (11%)
Query: 141 ETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVT 200
E G + E DLV+ ++AV +G R+G+G G+ D + KP ++
Sbjct: 144 EPTGAVLPPEALEKADLVIAPALAVDPQGNRLGRGAGWYD------RALARRKPACPLIA 197
Query: 201 TVHDCQVFD-TLPAELFGPHDVPIDIIVTP 229
+V D LPAE PHDVP D ++TP
Sbjct: 198 VCWPWEVLDIDLPAE---PHDVPADGVLTP 224
>UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1;
Neptuniibacter caesariensis|Rep: Putative
uncharacterized protein - Neptuniibacter caesariensis
Length = 194
Score = 41.5 bits (93), Expect = 0.022
Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 10/138 (7%)
Query: 92 PVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIED 151
P+ +C + K +Y+PV L NRL +R S E +P +
Sbjct: 60 PLIKLCWKLGKEVYLPV--LHPILHNRLWFVPYTQKTPMVRNIYSIR--EPKLEPGRRKA 115
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIK-PDTVVVTTVHDCQVFDT 210
+LDLV++ VA +G R+G G GY D F K ++ PD ++ H+ Q +
Sbjct: 116 AWALDLVLLPLVAFDPKGNRMGMGGGYYDRTFAFKGLKKGMRGPD--LIGLAHEIQRVEE 173
Query: 211 LPAELFGPHDVPIDIIVT 228
LP E + D+P+ IVT
Sbjct: 174 LPVEGW---DIPLTTIVT 188
>UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; Shewanella baltica|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Shewanella baltica OS195
Length = 235
Score = 41.5 bits (93), Expect = 0.022
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+V+ VA G R+G G GY D +K + + HDCQ +LP E
Sbjct: 162 LDVVITPLVAFDLMGNRMGMGGGYYDRTLANWQ----LKGKPLPMGYAHDCQQVVSLPCE 217
Query: 215 LFGPHDVPIDIIVTPTQVI 233
+ DVP+ I+TP++V+
Sbjct: 218 HW---DVPLPFIITPSRVL 233
>UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Desulfotomaculum reducens MI-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Desulfotomaculum
reducens MI-1
Length = 191
Score = 41.5 bits (93), Expect = 0.022
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 10/90 (11%)
Query: 145 KPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
+P+ +++ LDL+V+ +G R+G G GY D + ++ D V V +
Sbjct: 111 RPVEVQE---LDLIVVPGTVFDHQGNRMGYGGGYYD------RFIPRLRKDAVTVALAFE 161
Query: 205 CQVFDTLPAELFGPHDVPIDIIVTPTQVIE 234
QV + + L G +D P+ IVT Q+I+
Sbjct: 162 FQVRENF-SVLMGKYDQPVQFIVTEKQIIQ 190
>UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=3; Clostridium perfringens|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Clostridium perfringens (strain SM101 / Type A)
Length = 192
Score = 41.1 bits (92), Expect = 0.029
Identities = 44/174 (25%), Positives = 79/174 (45%), Gaps = 21/174 (12%)
Query: 70 LAELDVFKNANTV--KVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETG 127
L E +++KN+ V VN D V +I V VP++ + L E +
Sbjct: 33 LLESEIYKNSKVVFIYVNMDSEVNTVEIIKELLASDKKVAVPKVIP-----VSLKERQMK 87
Query: 128 PAAIRKAVSRNGMETYG--KP-IGIED-TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEF 183
I + N +G +P I +D + +DL+++ +A +G R+G G G+ D
Sbjct: 88 ALKIDSLLQLNESGAFGILEPSIECKDISEEVDLIIIPGLAFDLKGNRLGYGGGFYD--- 144
Query: 184 GLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
+ P++ V +D QVFD +P E F D +D+I++ ++I ++
Sbjct: 145 ----RFLSKYPNSKRVALCYDFQVFDEIPHEFF---DEKVDLIISEEKIISLKK 191
>UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
n=1; Orientia tsutsugamushi Boryong|Rep:
5-Formyltetrahydrofolate cyclo-ligase - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 190
Score = 41.1 bits (92), Expect = 0.029
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 7/90 (7%)
Query: 146 PIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
P+G + + L+V G V GYRIG G+GY D + +++I + + + D
Sbjct: 108 PVGTDIVIPSALLVPGLV-FDVAGYRIGFGKGYYD---QYISQVRSINSNNIAIGVCFDV 163
Query: 206 QVFDTLPAELFGPHDVPIDIIVTPTQVIET 235
Q+ + +P EL HD +D I+T +I T
Sbjct: 164 QLRNFVPREL---HDQKMDYIITNKILIVT 190
>UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Geobacter|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Geobacter sulfurreducens
Length = 187
Score = 40.7 bits (91), Expect = 0.038
Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 9/78 (11%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
D++V+ VA G+RIG G+G+ D + H++ +V +D Q+ D + E
Sbjct: 115 DIIVVPGVAFDLAGHRIGYGKGFYD---RALHHLEGTGR---LVGFCYDFQLVDEIRGE- 167
Query: 216 FGPHDVPIDIIVTPTQVI 233
PHDV +D+IVT ++I
Sbjct: 168 --PHDVALDLIVTEKRII 183
>UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Methylococcus capsulatus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Methylococcus capsulatus
Length = 221
Score = 40.7 bits (91), Expect = 0.038
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 13/131 (9%)
Query: 99 EQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGM-ETYGKPIGIEDTVSLDL 157
E+ +T ++P+ R T + GPAA+R +R G+ E I D LDL
Sbjct: 88 ERGRTAFIPLLRKHTLWFGPY------VGPAALRP--NRYGIPEPAIDGRMITDARELDL 139
Query: 158 VVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFG 217
V + VA G+R+G G GY D F + A + ++ + Q + L A
Sbjct: 140 VFVPLVAFDPRGHRLGMGGGYYDRTFAFRLAEPA-RASPRLIGLAFEGQKVERLEAR--- 195
Query: 218 PHDVPIDIIVT 228
P DVP+D VT
Sbjct: 196 PWDVPLDTAVT 206
>UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; uncultured bacterium 311|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
uncultured bacterium 311
Length = 192
Score = 40.7 bits (91), Expect = 0.038
Identities = 18/35 (51%), Positives = 23/35 (65%)
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFG 184
E+ LDLVV+ VA EG+R+G G+GY D FG
Sbjct: 113 ENASQLDLVVIPLVAFDNEGFRLGMGKGYYDFTFG 147
>UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Congregibacter litoralis KT71|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Congregibacter litoralis KT71
Length = 217
Score = 40.7 bits (91), Expect = 0.038
Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 9/93 (9%)
Query: 141 ETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVT 200
E G P+ D L LV++ +V + G+R+G G GY D FG A + V
Sbjct: 131 EPTGTPVPPRD---LQLVILPTVGWTARGFRLGMGGGYYDRFFGSKQASSAKR-----VA 182
Query: 201 TVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
+DCQ D L +L D P+D ++T + ++
Sbjct: 183 LAYDCQRDDAL-EQLKEAWDQPLDAVLTESGIL 214
>UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanocorpusculum labreanum Z|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 196
Score = 40.7 bits (91), Expect = 0.038
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 10/85 (11%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
S+D+V++ V + G+R+G G GY D F PD + + CQ + +P
Sbjct: 114 SIDVVLVPMVGFDRAGHRLGYGAGYYDRFF-------EKNPDIPRIGMAYACQEVELIPT 166
Query: 214 ELFGPHDVPIDIIVTPTQVIETQRM 238
E P D +D +VT +VI R+
Sbjct: 167 E---PFDARMDYVVTEDEVIRCGRV 188
>UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC
14580|Rep: YqgN - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 190
Score = 40.3 bits (90), Expect = 0.051
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 11/78 (14%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+D +++ + + GYRIG G GY D ++ DT + +CQV +P E
Sbjct: 116 IDFILVPGICYDRRGYRIGYGGGYYD------RYLAGFTKDT--ASLAFECQVIGHVPNE 167
Query: 215 LFGPHDVPIDIIVTPTQV 232
PHD+P+ ++T V
Sbjct: 168 ---PHDIPVKQVLTEDAV 182
>UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=20; Rhodobacterales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Silicibacter sp. (strain TM1040)
Length = 195
Score = 40.3 bits (90), Expect = 0.051
Identities = 25/89 (28%), Positives = 46/89 (51%), Gaps = 7/89 (7%)
Query: 149 IEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVF 208
++D +++++ VA G R+G G G+ D + +A T+ + D Q
Sbjct: 113 VDDYFDPEILIVPLVAFDAAGNRLGYGGGFYDRTLDRLRAQRA----TLAIGFAFDAQEA 168
Query: 209 DTLPAELFGPHDVPIDIIVTPTQVIETQR 237
+ LP E P D P+D+IVT ++V++ +R
Sbjct: 169 EGLPLE---PTDQPLDMIVTESRVLDFKR 194
>UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Psychromonas ingrahamii (strain 37)
Length = 196
Score = 40.3 bits (90), Expect = 0.051
Identities = 27/76 (35%), Positives = 36/76 (47%), Gaps = 6/76 (7%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDL+ VA +G RIG G GY D ++ K + HDCQ LP E
Sbjct: 122 LDLIFTPLVAFDTQGNRIGMGGGYYD---RMLAPWFKDKTGPYPIGLAHDCQQVQQLPVE 178
Query: 215 LFGPHDVPIDIIVTPT 230
+ DVP+ I+TP+
Sbjct: 179 EW---DVPLPEIITPS 191
>UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Sphingomonas sp. SKA58|Rep:
5-formyltetrahydrofolate cyclo-ligase - Sphingomonas sp.
SKA58
Length = 196
Score = 39.9 bits (89), Expect = 0.067
Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 10/82 (12%)
Query: 153 VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
VS D++V VA + R+G+G GY D A P+ + + Q D +P
Sbjct: 121 VSPDVIVTPLVAFDRSMNRLGQGGGYYD-------RALARFPEALRIGVAWSAQELDAVP 173
Query: 213 AELFGPHDVPIDIIVTPTQVIE 234
A+ P D+P+D+++T +VIE
Sbjct: 174 AD---PWDLPLDMVLTEVEVIE 192
>UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=17; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Alteromonas macleodii 'Deep ecotype'
Length = 229
Score = 39.9 bits (89), Expect = 0.067
Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 8/87 (9%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMH----MKAIKPD-TVVVTTVHDCQ 206
T D+++M V G R+G G GY D K I + +V HD Q
Sbjct: 140 TSQCDVILMPLVGFDTNGNRLGMGGGYYDRTLAFTQRNVYPQKNISSNKPKLVGIAHDMQ 199
Query: 207 VFDTLPAELFGPHDVPIDIIVTPTQVI 233
+ LP + DVP+D IVTPT+ +
Sbjct: 200 EVEALPVASW---DVPLDAIVTPTRTL 223
>UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4;
Neisseria|Rep: Putative uncharacterized protein -
Neisseria meningitidis serogroup C / serotype 2a (strain
ATCC 700532 /FAM18)
Length = 219
Score = 39.9 bits (89), Expect = 0.067
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 10/130 (7%)
Query: 104 LYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSV 163
LY+P ++ + PE IR N + G+ I + L ++++ V
Sbjct: 98 LYLPYIEPRSRRMWFTPYPESGMERERIRGRARLNVPQFAGRKIRVH---GLSVLLVPLV 154
Query: 164 AVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPI 223
+ +EGYR+G+ GY D M + ++ TV V CQ+ D L E HD+P+
Sbjct: 155 GIDREGYRLGQAGGYYDATLAAMKY--RLQAKTVGVGFA--CQLVDRLSVE---AHDLPL 207
Query: 224 DIIVTPTQVI 233
D V+ ++
Sbjct: 208 DGFVSEAGIL 217
>UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Candidatus Methanoregula boonei 6A8|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methanoregula
boonei (strain 6A8)
Length = 188
Score = 39.5 bits (88), Expect = 0.089
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 15/97 (15%)
Query: 142 TYG--KPIGIE---DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDT 196
T+G +PIG E + +D++V+ + + G RIG G GY D A PD
Sbjct: 98 TFGVPEPIGSEIPANPKDVDVIVLPMLGFDRTGGRIGYGAGYYD-------RFLAQNPDL 150
Query: 197 VVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
V + CQ + LP + +D+ +D+IVT ++
Sbjct: 151 VKIGVAFGCQEMEHLPVD---ENDIKMDLIVTEDGIV 184
>UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium diphtheriae|Rep: Putative
uncharacterized protein - Corynebacterium diphtheriae
Length = 194
Score = 39.1 bits (87), Expect = 0.12
Identities = 23/75 (30%), Positives = 40/75 (53%), Gaps = 11/75 (14%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+DL+++ ++ ++ G R+G+G GY D + + TV + + D +V T+P
Sbjct: 124 VDLIIVPALGITPSGRRLGQGAGYYD------RALAGVATPTVAI--LFDSEVNTTIP-- 173
Query: 215 LFGPHDVPIDIIVTP 229
F PHD D I+TP
Sbjct: 174 -FEPHDATCDWIITP 187
>UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Symbiobacterium thermophilum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Symbiobacterium
thermophilum
Length = 197
Score = 39.1 bits (87), Expect = 0.12
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 10/79 (12%)
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
ED ++DLVV+ VA + G R+G G GY D + AI + Q+ +
Sbjct: 114 EDPRAVDLVVVPGVAFDRRGRRLGYGGGYYDRLLPQLARAAAI-------GLGYGFQLVE 166
Query: 210 TLPAELFGPHDVPIDIIVT 228
LPAE HDVP+D + T
Sbjct: 167 RLPAE---AHDVPLDALAT 182
>UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Desulfuromonas acetoxidans DSM 684|Rep:
5-formyltetrahydrofolate cyclo-ligase - Desulfuromonas
acetoxidans DSM 684
Length = 184
Score = 39.1 bits (87), Expect = 0.12
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 13/92 (14%)
Query: 145 KPIGIEDTV--SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDT-VVVTT 201
+P G + LDLVV+ VA + G R+G G+G+ D F ++P + ++V
Sbjct: 101 EPTGCQQVAVNQLDLVVVPGVAFGRCGSRLGYGKGFYDQTF-------EVRPSSCLLVGL 153
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
Q+ D LP E HD+ +D IVT +++
Sbjct: 154 GFSFQLEDDLPKE---SHDIGLDYIVTDEEIL 182
>UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Cenarchaeum symbiosum|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Cenarchaeum symbiosum
Length = 173
Score = 39.1 bits (87), Expect = 0.12
Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 11/84 (13%)
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFD 209
E+ + D++++ +V +++G R+G GRGY D F + + +I P + Q+
Sbjct: 99 EECIDPDVIIVPAVGTARDGSRLGYGRGYYD-RFLAGLDIPSIVP-------CYSKQLVK 150
Query: 210 TLPAELFGPHDVPIDIIVTPTQVI 233
++P E HD+P++ IVT + I
Sbjct: 151 SVPTE---EHDIPVNWIVTEDETI 171
>UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=12; Euteleostomi|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Oryctolagus cuniculus (Rabbit)
Length = 201
Score = 39.1 bits (87), Expect = 0.12
Identities = 23/101 (22%), Positives = 46/101 (45%)
Query: 99 EQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLV 158
+Q K ++P RLQ+ ++ ++L + + + + + + T LDL+
Sbjct: 73 QQGKVCFIPRYRLQSNHMDMVKLASADEISSLPKTSWNIHQPSESDTREEALATGGLDLI 132
Query: 159 VMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
M + + G R+G+GRGY D + + KP T+ +
Sbjct: 133 FMPGLGFDRNGNRLGRGRGYYDTYLQRCLQQQGAKPYTIAL 173
>UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2;
Tropheryma whipplei|Rep: Putative uncharacterized
protein - Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 203
Score = 38.7 bits (86), Expect = 0.16
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 6/57 (10%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
D++++ + AV K GYR+G G+GY D ++ +K V V D ++FD +P
Sbjct: 120 DVMLIPAAAVDKRGYRLGWGKGYYD------RYLARVKRSIPVFAVVFDNEIFDEIP 170
>UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Xanthobacter autotrophicus Py2|Rep:
5-formyltetrahydrofolate cyclo-ligase - Xanthobacter sp.
(strain Py2)
Length = 195
Score = 38.7 bits (86), Expect = 0.16
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 7/73 (9%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
+L+++ A + G+RIG G G+ D L+ + ++ + CQ D +P E
Sbjct: 119 ELLLVPLAAFDRRGFRIGYGAGFYDRTLALLRAQRPVR----AIGFAFACQEVDQVPVE- 173
Query: 216 FGPHDVPIDIIVT 228
HD P+D++VT
Sbjct: 174 --THDEPVDMMVT 184
>UniRef50_A1A037 Cluster: Putative uncharacterized protein; n=2;
Bifidobacterium adolescentis|Rep: Putative
uncharacterized protein - Bifidobacterium adolescentis
(strain ATCC 15703 / DSM 20083)
Length = 206
Score = 38.7 bits (86), Expect = 0.16
Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
G E S +L+++ + AV + G+R+G+G G+ D + ++ V V +
Sbjct: 125 GPEVLTSAELIIVPAFAVDEHGFRLGRGGGWYD----RALEHRSSTARVVAVCWPWE-PT 179
Query: 208 FDTLPAELFGPHDVPIDIIVTP 229
+T+P E PHD+P+D ++TP
Sbjct: 180 DETVPHE---PHDIPVDGVLTP 198
>UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=6; Bacteroides|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Bacteroides
thetaiotaomicron
Length = 196
Score = 38.3 bits (85), Expect = 0.20
Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 14/94 (14%)
Query: 142 TYG--KPIG--IEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTV 197
TYG +P+G D +D + + VA ++G R+G+G+GY D L+ + P
Sbjct: 97 TYGIEEPVGETFTDYADIDFIAVPGVAFDRKGNRLGRGKGYYD---RLLPRI----PAAY 149
Query: 198 VVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQ 231
Q+ + +PAE F D+ +DII+T +
Sbjct: 150 KAGICFPFQIVEEVPAEAF---DICMDIIITSNE 180
>UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2;
Synechococcus elongatus|Rep: Putative uncharacterized
protein - Synechococcus sp. (strain PCC 7942) (Anacystis
nidulans R2)
Length = 189
Score = 38.3 bits (85), Expect = 0.20
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 8/74 (10%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+DL+++ +VAV KEGYR+G G GY D + + + Q+ LP +
Sbjct: 116 IDLLIVPAVAVDKEGYRLGYGGGYYD-----RLRADPAWRSIPAIVVAYAAQIMSELPHD 170
Query: 215 LFGPHDVPIDIIVT 228
P D+P + T
Sbjct: 171 ---PWDIPFSAVCT 181
>UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Hahella chejuensis KCTC 2396|Rep:
5-formyltetrahydrofolate cyclo-ligase - Hahella
chejuensis (strain KCTC 2396)
Length = 190
Score = 38.3 bits (85), Expect = 0.20
Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
SL +V VA K+G R+G G GY D F + I ++ H Q F LP
Sbjct: 108 SLHVVCFPLVAFDKQGNRLGMGGGYYDRTFA---DRRVIIKRPKLIGFAHHFQQFPELPH 164
Query: 214 ELFGPHDVPIDIIVTPTQV 232
E P D+P+ + T Q+
Sbjct: 165 E---PWDIPLSAVATDQQL 180
>UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Moorella thermoacetica (strain ATCC 39073)
Length = 202
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 9/84 (10%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D +DLV++ VA + G R+G G GY D + ++P + + Q+
Sbjct: 113 DPGDIDLVLVPGVAFDRAGNRLGYGGGYYD------RFLATLRPGALTIALAFAEQIVAD 166
Query: 211 LPAELFGPHDVPIDIIVTPTQVIE 234
+ E+ HD P+D++VT ++I+
Sbjct: 167 VYPEV---HDRPVDMVVTDQEIIK 187
>UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Geobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacter sp. FRC-32
Length = 201
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/95 (30%), Positives = 49/95 (51%), Gaps = 9/95 (9%)
Query: 139 GMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVV 198
G+E G+ I ++D+ V+ VA G RIG G+G+ D +H+ ++
Sbjct: 114 GIEEPGEKNIIHLPETIDIFVIPGVAFDINGRRIGYGKGFYD----RTLHL--LEGCGKF 167
Query: 199 VTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
V +D Q+ D + E PHDV +D+I + T++I
Sbjct: 168 VGLCYDFQLVDEIVGE---PHDVTMDLIFSETRII 199
>UniRef50_Q0S4X5 Cluster: Putative uncharacterized protein; n=1;
Rhodococcus sp. RHA1|Rep: Putative uncharacterized
protein - Rhodococcus sp. (strain RHA1)
Length = 192
Score = 38.3 bits (85), Expect = 0.20
Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 10/85 (11%)
Query: 146 PIGIEDTV-SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
P+ D + S + + ++AV + G R+G+G G+ D GL D ++T V D
Sbjct: 107 PVWEPDEIRSAGTIFVPALAVDRRGVRLGRGAGFYDRSLGL------ASSDARLITVVRD 160
Query: 205 CQVFDTLPAELFGPHDVPIDIIVTP 229
++ LP + PHDV + +TP
Sbjct: 161 EELVSELPED---PHDVRMGWALTP 182
>UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Maricaulis maris MCS10|Rep:
5-formyltetrahydrofolate cyclo-ligase - Maricaulis maris
(strain MCS10)
Length = 199
Score = 38.3 bits (85), Expect = 0.20
Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
LV++ +A + G R+G G+GY D + ++ V DCQV T+PAE
Sbjct: 118 LVLVPLLACDRSGNRLGFGKGYYDYTLAALRAAGQVR----AVGLAFDCQVLATIPAE-- 171
Query: 217 GPHDVPIDIIVT 228
HD +D +VT
Sbjct: 172 -RHDQALDGVVT 182
>UniRef50_A6S505 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 113
Score = 38.3 bits (85), Expect = 0.20
Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 4/79 (5%)
Query: 190 KAIKPDTVVVTTVHDCQVFDTLPAELFGPH-DVPIDIIVTPTQVIETQRMSQRPTGILWH 248
+A+ DT + VH+CQV L E G D D ++T ++I ++ GI+W
Sbjct: 8 RAVNKDTKTIALVHECQV---LEEEFKGDQWDAGCDYVITNKRIITVAGAAKPGYGIIWD 64
Query: 249 LLSNRRLQLMPILGQLRDI 267
L L+ + L +L++I
Sbjct: 65 KLDRGMLEDIESLRELKNI 83
>UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 187
Score = 38.3 bits (85), Expect = 0.20
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 11/91 (12%)
Query: 147 IGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQ 206
I E +LD++++ +V ++ +G R+G G G+ D F L H K T+ +T + Q
Sbjct: 108 IDCETENNLDVILVPTVGITPKGIRLGYGHGFYD-RF-LSNH----KISTISLTL--EKQ 159
Query: 207 VFDTLPAELFGPHDVPIDIIVTPTQVIETQR 237
V +P HD+ ID +VT ++I+T R
Sbjct: 160 VVKNIPK---SDHDILIDWVVTEDRIIDTHR 187
>UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=29; Streptococcus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Streptococcus pneumoniae
Length = 179
Score = 37.9 bits (84), Expect = 0.27
Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 12/79 (15%)
Query: 149 IEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVF 208
+ D +DL+ + +A + +GYRIG G GY D +++ T ++T++ CQ+
Sbjct: 107 VVDASQIDLIHVPGLAFTTKGYRIGYGGGYYD------RYLEHFSGRT--LSTIYPCQIQ 158
Query: 209 DTLPAELFGPHDVPIDIIV 227
D +P HD+P+ ++
Sbjct: 159 DFIPEN----HDIPVQEVL 173
>UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Nocardioides sp. (strain BAA-499 / JS614)
Length = 194
Score = 37.9 bits (84), Expect = 0.27
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 137 RNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDT 196
R +E + +G E + D+V+ +AVS G R+G+G G D G + T
Sbjct: 104 RGLLEPDAERLGPEAIGTADVVLTPGLAVSPSGVRLGRGGGCYDRALG------RVPVGT 157
Query: 197 VVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
++D +V +P E PHD P+ TP+ V+
Sbjct: 158 FTCVLLYDGEVGLDVPVE---PHDRPVLFAATPSGVV 191
>UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Salinibacter ruber DSM 13855|Rep:
5-formyltetrahydrofolate cyclo-ligase - Salinibacter
ruber (strain DSM 13855)
Length = 195
Score = 37.5 bits (83), Expect = 0.36
Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 11/80 (13%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
++D+V + ++ V ++G+RIG G GY D + + ++ V T C V +LP
Sbjct: 125 AIDVVFVPALGVGQDGHRIGHGSGYYD---AFLQSVACLR----VALTYEACLV-PSLPN 176
Query: 214 ELFGPHDVPIDIIVTPTQVI 233
HDVP+ IVT QV+
Sbjct: 177 ---ASHDVPVTTIVTEQQVL 193
>UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 194
Score = 37.5 bits (83), Expect = 0.36
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 11/84 (13%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
LV++ V + G RIG G GY D ++K + D + V D Q + + E+
Sbjct: 119 LVIVPGVVFDRAGNRIGYGGGYYD------SYLK--QADCIKVGVAFDFQCVEQIVPEV- 169
Query: 217 GPHDVPIDIIVTPTQVIETQRMSQ 240
HDVP+D I+T ++I ++ Q
Sbjct: 170 --HDVPVDYIITEKEMITCRQACQ 191
>UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Nitrococcus mobilis Nb-231|Rep:
5-formyltetrahydrofolate cyclo-ligase - Nitrococcus
mobilis Nb-231
Length = 210
Score = 37.5 bits (83), Expect = 0.36
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDLV++ VA ++G+R+G G G+ D F + H + ++ Q LP E
Sbjct: 119 LDLVLVPLVAFDQQGHRLGMGAGFYDHTFAFLRHQRGRWRRPRLLGIAFSFQRIVELPVE 178
Query: 215 LFGPHDVPIDIIVT 228
P DVP+ + T
Sbjct: 179 ---PWDVPLAGVAT 189
>UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=1; Bacillus coagulans 36D1|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Bacillus coagulans 36D1
Length = 191
Score = 37.5 bits (83), Expect = 0.36
Identities = 24/81 (29%), Positives = 45/81 (55%), Gaps = 11/81 (13%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
++DL+++ + K+G+RIG G GY D A P+ V+ +H CQ+ +P+
Sbjct: 116 AIDLLIVPGLVFDKKGFRIGFGGGYYD-------RFLAGFPNQ-TVSLIHSCQLKAHVPS 167
Query: 214 ELFGPHDVPIDIIVTPTQVIE 234
E +D+P+ IVT + +++
Sbjct: 168 E---SYDIPVRQIVTESGMLK 185
>UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Porphyromonas gingivalis|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 185
Score = 37.1 bits (82), Expect = 0.47
Identities = 39/172 (22%), Positives = 78/172 (45%), Gaps = 16/172 (9%)
Query: 63 AQEAAAKLAELDVFKNANTVKVNPDKPQEP-VRVICLEQQKTLYVPVPRLQTGFLNRLEL 121
+Q ++ LD+F +A + + P EP + + E +T + +PR++ +
Sbjct: 27 SQSIIERIRRLDIFADAKRIGLYHALPDEPDLTGLLREYVQTKQLFIPRVEGDDIAFYAY 86
Query: 122 PEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDL 181
TG A + + E SLDL+++ VA ++G R+G+G+GY D
Sbjct: 87 ----TGEADLEAEGAYGIAEPTADAATAILPSSLDLLLVPGVAFDRKGSRMGRGKGYYD- 141
Query: 182 EFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
+ A + + VT + ++ + LP + P D P+D ++T ++ +
Sbjct: 142 -----RFLPATQVRLIGVTFSY--RLLEELPTD---PWDRPMDGVITESETL 183
>UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Desulfovibrio vulgaris subsp.
vulgaris|Rep: 5-formyltetrahydrofolate cyclo-ligase
family protein - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 283
Score = 37.1 bits (82), Expect = 0.47
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 8/82 (9%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTL 211
T + DL ++ VA ++G R+G G GY D F M A T +V H Q+ D L
Sbjct: 208 TFAPDLAIIPGVAFDRQGNRLGYGGGYYD-RFLSTPGMSA----TPLVGFAHAFQIVDAL 262
Query: 212 PAELFGPHDVPIDIIVTPTQVI 233
PAE + D P++ + T +I
Sbjct: 263 PAEAW---DRPVNALCTEEGLI 281
>UniRef50_Q6MNQ4 Cluster: InterPro: 5-formyltetrahydrofolate
cyclo-ligase; n=1; Bdellovibrio bacteriovorus|Rep:
InterPro: 5-formyltetrahydrofolate cyclo-ligase -
Bdellovibrio bacteriovorus
Length = 189
Score = 37.1 bits (82), Expect = 0.47
Identities = 37/131 (28%), Positives = 62/131 (47%), Gaps = 23/131 (17%)
Query: 109 PRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKE 168
P+++ G L E + + GP +R+ + + + G L+V G V +K
Sbjct: 77 PKMREGLLEFYETRDFDLGPYGVREPKPGSFQRSLAEMSG--------LLVPGLV-FNKN 127
Query: 169 GYRIGKGRGYGDLEFGLMMHMKAIKP-DTVVVTTVHDCQV-FDTLPAELFGPHDVPIDII 226
G R+GKG+G+ D K +K V V D QV D LP E PHDV +D +
Sbjct: 128 GNRLGKGKGFYD---------KTLKSFPGVKVGIGFDFQVTADPLPTE---PHDVKMDFL 175
Query: 227 VTPTQVIETQR 237
+T + +++ ++
Sbjct: 176 ITESGLVDCKK 186
>UniRef50_Q2GER3 Cluster: 5,10-methenyltetrahydrofolate synthetase;
n=1; Neorickettsia sennetsu str. Miyayama|Rep:
5,10-methenyltetrahydrofolate synthetase - Neorickettsia
sennetsu (strain Miyayama)
Length = 193
Score = 37.1 bits (82), Expect = 0.47
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
+LV + VA + + +R+G GRG+ D + H ++ +T+ + +D Q+ L E
Sbjct: 111 ELVFVPLVAFNCDRHRLGFGRGFFDR---FINHSRSNGCNTLYIGLAYDEQLCHDLVIEA 167
Query: 216 FGPHDVPIDIIVTPTQVIET 235
HD +D I+TPT V +T
Sbjct: 168 ---HDQALDSIITPTTVYQT 184
>UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Gammaproteobacteria|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Marinobacter algicola DG893
Length = 216
Score = 37.1 bits (82), Expect = 0.47
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
+LD V+ V G R+G G G+ D F + P ++ HDCQ LP
Sbjct: 134 ALDAVLFPLVGFDGFGGRLGMGGGFYDRTFAFTRIRPRLAPK--LIGLAHDCQKVLELPL 191
Query: 214 ELFGPHDVPIDIIVT 228
E P D+P+ +VT
Sbjct: 192 E---PWDIPLHSVVT 203
>UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2;
Bacillus|Rep: Uncharacterized protein yqgN - Bacillus
subtilis
Length = 187
Score = 37.1 bits (82), Expect = 0.47
Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 11/79 (13%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+DL+++ V G+R+G G GY D ++ + T V+ + +CQ+F +P
Sbjct: 116 IDLMIVPGVCFDVNGFRVGFGGGYYD------RYLSEYEGKT--VSLLLECQLFAHVPRL 167
Query: 215 LFGPHDVPIDIIVTPTQVI 233
PHD+P+ ++T ++I
Sbjct: 168 ---PHDIPVHKLITEDRII 183
>UniRef50_Q98N02 Cluster: Mll0364 protein; n=4; Rhizobiales|Rep:
Mll0364 protein - Rhizobium loti (Mesorhizobium loti)
Length = 197
Score = 36.7 bits (81), Expect = 0.63
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 10/84 (11%)
Query: 146 PIGIE-DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
PI E D V D+V+ V + YR+G G G+ D M KP +V+ ++
Sbjct: 121 PIPAEGDPVLPDIVIAPIVGIDPANYRLGYGGGFFDRTLAAM----PFKP--LVIGVGYE 174
Query: 205 CQVFDTLPAELFGPHDVPIDIIVT 228
Q T+ + PHD+P+D IVT
Sbjct: 175 LQRIATICPQ---PHDIPMDRIVT 195
>UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Thiomicrospira crunogena XCL-2|Rep:
5-formyltetrahydrofolate cyclo-ligase - Thiomicrospira
crunogena (strain XCL-2)
Length = 192
Score = 36.7 bits (81), Expect = 0.63
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDLV+M EG+R G G G+ D F ++ H+CQ + + E
Sbjct: 115 LDLVLMPLTCFDLEGHRTGMGGGFYDRTFQFKRWQTHRHNRPKLIGWAHECQQVEHIQPE 174
Query: 215 LFGPHDVPIDIIVT 228
P D+P++ +VT
Sbjct: 175 ---PWDIPLEGLVT 185
>UniRef50_Q2RVG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Rhodospirillaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Rhodospirillum rubrum (strain ATCC 11170
/ NCIB 8255)
Length = 250
Score = 36.7 bits (81), Expect = 0.63
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
Query: 135 VSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKP 194
V + + T+ +P+ + V+ +++ +A G+R+G+G G+ D + + A
Sbjct: 145 VDQGALGTF-QPLSLAPLVTPSWLLVPLLAFDDAGHRLGQGGGFYD---RTLAGLGAAGS 200
Query: 195 DTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQV 232
V + + Q + LP E PHD P+D ++T V
Sbjct: 201 PVVAIGVAYAAQQVEALPVE---PHDRPLDGVITEAGV 235
>UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; gamma proteobacterium HTCC2207|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
gamma proteobacterium HTCC2207
Length = 195
Score = 36.7 bits (81), Expect = 0.63
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 20/178 (11%)
Query: 63 AQEAAAKLAELDVFKNANTVKVN--PDKPQEPVRVI--CLEQQKTLYVP-VPRLQTGFLN 117
+++ A L D F+ A + + D +P ++ +K ++P + L+ L+
Sbjct: 26 SEQLAKLLCRQDFFQRAKRIGIYLANDGEIDPSAIVTAAFRAKKACFLPLIDPLKANSLH 85
Query: 118 RLELPEGETGPAAIRKAVSRNG-METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGR 176
E G+T + K +R G +E + I SLDL+++ VA + G R+G G
Sbjct: 86 FAEYQLGDT----LHK--NRFGILEPQFRSTAITPPWSLDLILLPLVAFDRAGNRLGMGG 139
Query: 177 GYGDLEFGLMMHMKAIKPDTV-VVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVI 233
G+ D + + KP+ V ++ H CQ L + + D+P+ I T ++I
Sbjct: 140 GFYD----RTLAPRPGKPNNVKLIGLAHQCQEVSGLSPQSW---DIPLHKIATDQEII 190
>UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Chlorobium/Pelodictyon group|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
ferrooxidans DSM 13031
Length = 207
Score = 36.7 bits (81), Expect = 0.63
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 6/77 (7%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D LD+V++ +A + GYR+G G+G+ D F + ++ +P + + Q+ DT
Sbjct: 128 DEAMLDVVLIPLLAFDRSGYRLGYGKGFYD-RFLHRLSLEGFRP--LRIGLAFSMQMIDT 184
Query: 211 LPAELFGPHDVPIDIIV 227
+P + + D P+D +V
Sbjct: 185 VPHDSW---DEPLDGVV 198
>UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Mariprofundus ferrooxydans PV-1
Length = 190
Score = 36.7 bits (81), Expect = 0.63
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 8/78 (10%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
++V VA + G R+G G+G D F L + +I V+ CQ +PAE
Sbjct: 117 ILVCPLVAFDQRGNRLGMGKGCFD--FWLAQYRSSIDQ---VIGLAFSCQQVAEVPAER- 170
Query: 217 GPHDVPIDIIVTPTQVIE 234
HD+P+D I+T +V +
Sbjct: 171 --HDMPMDFIITEKEVTQ 186
>UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8)(Marinobacter
hydrocarbonoclasticus (strain DSM 11845))
Length = 211
Score = 36.7 bits (81), Expect = 0.63
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
+LD V+ V + G R+G G G+ D F + P ++ HD Q + LP
Sbjct: 133 ALDAVLFPLVGFDETGGRLGMGGGFYDRTFAFSRIRPGMAPK--LIGLAHDFQRVEQLPV 190
Query: 214 ELFGPHDVPIDIIVT 228
E P DVP+ +VT
Sbjct: 191 E---PWDVPLHGVVT 202
>UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyces
cerevisiae YER183c FAU1 singleton; n=1; Kluyveromyces
lactis|Rep: Similarities with sp|P40099 Saccharomyces
cerevisiae YER183c FAU1 singleton - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 291
Score = 36.7 bits (81), Expect = 0.63
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 20/152 (13%)
Query: 91 EPVRVICLEQQKTLYVP----------VPRLQTGFLNRLELPEGETGPAAIRKAVSRNGM 140
EP+ +Q KT+Y+P V Q G L R L A +A+ G
Sbjct: 135 EPLVESLFKQGKTVYLPRCSSTSVSKQVDLRQDGALKRPHLVFYRFDSLAQVQALQPQGK 194
Query: 141 ETYGKPIGIED----TVSLDLVVMGSVAVSKE-GYRIGKGRGYGDLEFGLMMHMKAIKPD 195
+P+ + T +L++++M VA K+ G R+G G GY D +H KP
Sbjct: 195 YKLREPVRTDPEPLPTPALEVILMPGVAFCKKNGARMGHGAGYYDDYISRHIHYTGKKP- 253
Query: 196 TVVVTTVHDCQVFDTLPAELFGPHDVPIDIIV 227
++V + Q+ D +P E HD +D +V
Sbjct: 254 -LLVGLALEEQLVDDVPLE---QHDYTVDCLV 281
>UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Desulfitobacterium hafniense|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Desulfitobacterium hafniense (strain DCB-2)
Length = 194
Score = 36.3 bits (80), Expect = 0.83
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D + +D + + A +G R+G G GY D F + ++ T + CQ+ D
Sbjct: 115 DPLEIDGIFVPGAAFDGQGNRLGYGGGYYDRFF------ERVREGTPKIALAFHCQIVDR 168
Query: 211 LPAELFGPHDVPIDIIVT 228
+P E++ D +D+++T
Sbjct: 169 IPVEVY---DKKVDMLIT 183
>UniRef50_A6E7D7 Cluster: Thiol:disulfide interchange protein; n=1;
Pedobacter sp. BAL39|Rep: Thiol:disulfide interchange
protein - Pedobacter sp. BAL39
Length = 331
Score = 36.3 bits (80), Expect = 0.83
Identities = 16/49 (32%), Positives = 30/49 (61%)
Query: 190 KAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRM 238
KAIK D + T V D + +++ PA+L+G +P ++++ P VI + +
Sbjct: 269 KAIKDDELTWTHVSDLKFWNSEPAKLYGVRAIPSNVLIGPDGVIVARNL 317
>UniRef50_A4KQQ5 Cluster: 5-formyltetrahydroformate cycloligase;
n=11; Francisella tularensis|Rep:
5-formyltetrahydroformate cycloligase - Francisella
tularensis subsp. holarctica 257
Length = 182
Score = 36.3 bits (80), Expect = 0.83
Identities = 19/79 (24%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD++++ V + + +R+G G G+ D + K I + + D Q + +
Sbjct: 111 LDIIIVPMVGFTSDKFRMGMGGGFYDYN----LSFKKIHKWPLTIGIAFDEQQNNAI--- 163
Query: 215 LFGPHDVPIDIIVTPTQVI 233
+ HD+ +D+I+TPT+++
Sbjct: 164 IIDKHDIKLDLIITPTRIL 182
>UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Chlorobium phaeobacteroides DSM 266|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
phaeobacteroides (strain DSM 266)
Length = 216
Score = 36.3 bits (80), Expect = 0.83
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Query: 145 KPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
+P+ + D SLD V++ VA GYR+G G+G+ D F + + + + +
Sbjct: 129 RPV-MSDERSLDAVLVPVVAADHRGYRLGYGKGFYDRFFSRLAKAEC---NPLRIGLAFY 184
Query: 205 CQVFDTLPAELFGPHDVPIDIIV 227
Q+ +P + P D P+D IV
Sbjct: 185 MQILPRIPVD---PWDQPLDYIV 204
>UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2;
Ostreococcus|Rep: Predicted methyltransferase -
Ostreococcus tauri
Length = 515
Score = 36.3 bits (80), Expect = 0.83
Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 149 IEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMH--MKAIKPDTVVVTTVHDCQ 206
IE +LD++++ A ++G R+G+G GY D ++ +VV ++CQ
Sbjct: 110 IETVGALDVIIVPGFAFGEDGRRLGRGGGYYDAFLARYADACVRVNASPPLVVALAYECQ 169
Query: 207 VFDTLPAELFGPHDVPIDIIVTPTQ 231
+ + HD +D++VT ++
Sbjct: 170 ICPPGVVPI-DAHDRIVDVVVTESR 193
>UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Culicidae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Aedes aegypti (Yellowfever mosquito)
Length = 208
Score = 36.3 bits (80), Expect = 0.83
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGD---LEFGLMMHMKAIKPDTVVVTTVHDCQVF--D 209
LD++++ V ++ G+R+G G GY D LE+ + T +V Q+ D
Sbjct: 126 LDMIILPGVGFTRSGHRLGHGGGYYDRFLLEYFKKFPNASDNRKTYLVGVAFREQIVPED 185
Query: 210 TLPAELFGPHDVPIDIIVTPTQ 231
LP HD P+D+++ P +
Sbjct: 186 QLP---IAEHDFPLDMVIWPDE 204
>UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 214
Score = 36.3 bits (80), Expect = 0.83
Identities = 38/171 (22%), Positives = 75/171 (43%), Gaps = 19/171 (11%)
Query: 70 LAELDVFKNANTVKVNPDKPQEPVRV-----ICLEQQKTLYVP-------VPRLQTGFLN 117
L E + F++A +V V + P V+ C +QQK +++P + +++
Sbjct: 36 LLESEQFRSAKSVGVYMNMPTMEVQTESIIKACFDQQKAVFLPKCSSNARCEGRKKNYMS 95
Query: 118 RLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRG 177
+ +P G + + + + + +T LDL+++ +A +K G R+G G G
Sbjct: 96 MIHVPS--LGDVHNLEPQGKYRLLEPTEGTEVFNTAGLDLLILPGMAFTKSGRRLGHGAG 153
Query: 178 YGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELFGPHDVPIDIIVT 228
+ D + A P V + + Q+ D +P E HD +D I++
Sbjct: 154 FYDEFLTVYQSHFARVPYLVGLALLE--QIVDDIPHE---EHDWDLDCIIS 199
>UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=16; Euteleostomi|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Homo sapiens (Human)
Length = 203
Score = 36.3 bits (80), Expect = 0.83
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
T LDL+ M + K G R+G+G+GY D + + +KP T+ +
Sbjct: 126 TGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLAL 173
>UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Oceanobacillus iheyensis|Rep:
5-formyltetrahydrofolate cyclo-ligase - Oceanobacillus
iheyensis
Length = 186
Score = 35.9 bits (79), Expect = 1.1
Identities = 22/78 (28%), Positives = 41/78 (52%), Gaps = 11/78 (14%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
L L ++ + K GYRIG G GY D + +I+ T+ + + + Q+ ++P E
Sbjct: 117 LGLCIVPGIVFDKNGYRIGFGGGYYD------RILPSIQAPTLSICS--EVQIISSIPKE 168
Query: 215 LFGPHDVPIDIIVTPTQV 232
HD+ +D ++T T++
Sbjct: 169 ---SHDLSVDYLLTETRI 183
>UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=3; Sphingomonadales|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 195
Score = 35.9 bits (79), Expect = 1.1
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 10/77 (12%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
++V + V EG R+G+G G+ D + H A++ + DCQ+ D LP E
Sbjct: 121 EVVFVPLVGFDAEGGRLGQGGGHYDR--WIEAHPAAVR-----IGLAWDCQLVDRLPRE- 172
Query: 216 FGPHDVPIDIIVTPTQV 232
HD + +VTPT++
Sbjct: 173 --THDRALHAVVTPTRI 187
>UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-related protein; n=1; Clostridium kluyveri
DSM 555|Rep: 5-formyltetrahydrofolate
cyclo-ligase-related protein - Clostridium kluyveri DSM
555
Length = 181
Score = 35.9 bits (79), Expect = 1.1
Identities = 23/89 (25%), Positives = 45/89 (50%), Gaps = 10/89 (11%)
Query: 140 METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
+E + +E+T S+D+ + +A K G R+G G GY D +K ++ D+ +
Sbjct: 102 LEPQNTNLKVEET-SIDICYVPGLAFDKSGGRVGYGGGYYD------RFLKKLRNDSKKI 154
Query: 200 TTVHDCQVFDTLPAELFGPHDVPIDIIVT 228
+ Q+ D +P G +DV +D +++
Sbjct: 155 GLAYSFQILDKVP---MGKYDVCMDGVIS 180
>UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pelotomaculum thermopropionicum SI|Rep:
5-formyltetrahydrofolate cyclo-ligase - Pelotomaculum
thermopropionicum SI
Length = 203
Score = 35.9 bits (79), Expect = 1.1
Identities = 28/96 (29%), Positives = 46/96 (47%), Gaps = 11/96 (11%)
Query: 140 METYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
ME + + D LDLVV+ +A +GYR+G G G+ D + TV V
Sbjct: 115 MEPKPRCLRFVDPAGLDLVVVPGLAFDLKGYRLGYGSGFYD------RFLPLTGKGTVFV 168
Query: 200 TTVHDCQVFDTLPAELF-GPHDVPIDIIVTPTQVIE 234
++ Q L +++ HDVP+ I+T ++I+
Sbjct: 169 GLAYELQ----LQIDVYHRRHDVPVHYILTEERLID 200
>UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Caulobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 214
Score = 35.5 bits (78), Expect = 1.4
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 7/84 (8%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
DLVV +A ++G R+G+G GY D + + + V+ + Q + LP E
Sbjct: 137 DLVVTPLLAFQRDGVRLGQGGGYYDRALAFLRSRRPV----FVLGLAYSGQQAENLPHE- 191
Query: 216 FGPHDVPIDIIVTPTQVIETQRMS 239
HD +D I+T + I + M+
Sbjct: 192 --AHDQRLDAILTEKEYIAVKDMA 213
>UniRef50_Q82Y32 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Nitrosomonadaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Nitrosomonas europaea
Length = 208
Score = 35.5 bits (78), Expect = 1.4
Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 153 VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
+++D +++ + ++GYR+G G GY D + A+ P + + + T+
Sbjct: 117 ITVDSIIIPLLGFDEQGYRLGYGSGYFD------RTLAAMSPRPLAIGVAFEILRLPTIH 170
Query: 213 AELFGPHDVPIDIIVTPTQVI 233
+ HD+P+D IVT ++
Sbjct: 171 PQ---QHDIPMDYIVTEQSIL 188
>UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
n=1; Gluconobacter oxydans|Rep: 5-Formyltetrahydrofolate
cyclo-ligase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 195
Score = 35.5 bits (78), Expect = 1.4
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
DLV++ +A GYR+G G GY D ++ D + Q + +P
Sbjct: 118 DLVLVPFLAFDASGYRLGYGGGYYDRTLAML--------DVPAIGFGFAGQQVERVPR-- 167
Query: 216 FGPHDVPIDIIVTPTQVIET 235
GP+D+PI IVT +I T
Sbjct: 168 -GPYDIPIPAIVTERGIIRT 186
>UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Sll1643 protein - Synechocystis sp.
(strain PCC 6803)
Length = 188
Score = 35.5 bits (78), Expect = 1.4
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
++DL+++ +A ++GYR+G G GY D F + K V + + + + LP
Sbjct: 112 TVDLLLVPCLAGDRQGYRLGYGGGYYDRLFADPLWRAVPK-----VGILFEAGLREKLPH 166
Query: 214 ELFGPHDVPIDIIVTPTQVIETQ 236
+ P D+P+ +VT Q+I+ +
Sbjct: 167 D---PWDMPLQTLVTEKQIIQIE 186
>UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Exiguobacterium sibiricum 255-15|Rep:
5-formyltetrahydrofolate cyclo-ligase - Exiguobacterium
sibiricum 255-15
Length = 182
Score = 35.5 bits (78), Expect = 1.4
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 11/80 (13%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
S+DL ++ A ++ GYRIG G G+ D + TV VT DCQ+
Sbjct: 111 SVDLCLVPGRAFTRAGYRIGWGGGFYD------RALTDYPGHTVAVT--FDCQLVSDFEV 162
Query: 214 ELFGPHDVPIDIIVTPTQVI 233
E P D P+ IVT ++VI
Sbjct: 163 E---PFDQPVQKIVTESKVI 179
>UniRef50_Q6AAH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Propionibacterium acnes|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Propionibacterium acnes
Length = 195
Score = 35.1 bits (77), Expect = 1.9
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 9/76 (11%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+++V+ ++ V + GYR+G G G+ D +++H D V V+D ++ D +P +
Sbjct: 122 VEVVLCSALFVDRSGYRVGVGGGWYD---RVLVHR---ADDVPVWAVVNDDEILDEVPHD 175
Query: 215 LFGPHDVPIDIIVTPT 230
P D P+ +TP+
Sbjct: 176 ---PWDEPVTAALTPS 188
>UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Alcanivorax borkumensis SK2|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
11573)
Length = 193
Score = 35.1 bits (77), Expect = 1.9
Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 6/76 (7%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
+LD++++ +VA + GYR+G G GY D + +P ++ +D Q +
Sbjct: 119 ALDVIILPAVAFDEAGYRLGMGGGYYDRTLEQLTRYPR-RPR--LIAAGYDFQKME--QG 173
Query: 214 EL-FGPHDVPIDIIVT 228
EL P D P+D IVT
Sbjct: 174 ELPVAPWDQPVDCIVT 189
>UniRef50_A7I2Y8 Cluster: 5,10-methenyltetrahydrofolate synthetase;
n=1; Campylobacter hominis ATCC BAA-381|Rep:
5,10-methenyltetrahydrofolate synthetase - Campylobacter
hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146
/CH001A)
Length = 207
Score = 35.1 bits (77), Expect = 1.9
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 9/78 (11%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD+ ++ + V RIG G+GY D+ F H+K KP VV ++ D + AE
Sbjct: 111 LDMAIIPCIGVDGNFARIGHGKGYYDIFFS---HLKT-KP-IVVFVSLSD----NFTKAE 161
Query: 215 LFGPHDVPIDIIVTPTQV 232
+ HD+ D +TP ++
Sbjct: 162 ISQKHDLVGDFYITPKKI 179
>UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=12; Staphylococcus aureus|Rep:
5-formyltetrahydrofolate cyclo-ligase - Staphylococcus
aureus (strain Newman)
Length = 197
Score = 35.1 bits (77), Expect = 1.9
Identities = 16/31 (51%), Positives = 20/31 (64%)
Query: 150 EDTVSLDLVVMGSVAVSKEGYRIGKGRGYGD 180
E T +LDL+V+ V +GYRIG G GY D
Sbjct: 127 ETTNNLDLIVVPGVGFQDDGYRIGYGGGYYD 157
>UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Sagittula stellata E-37|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Sagittula stellata E-37
Length = 136
Score = 35.1 bits (77), Expect = 1.9
Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
+++++ VA S+ G R+G G G+ D + M+A +P T+ + Q LP E
Sbjct: 64 EILIVPLVAFSRSGGRLGYGGGFYDRT---LERMRAKRP-TLAIGFAFAGQEMVDLPLE- 118
Query: 216 FGPHDVPIDIIVTPTQVIE 234
D P+D+IVT ++IE
Sbjct: 119 --DTDQPLDLIVTEREIIE 135
>UniRef50_Q4ULB4 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
n=1; Rickettsia felis|Rep: 5-Formyltetrahydrofolate
cyclo-ligase - Rickettsia felis (Rickettsia azadi)
Length = 144
Score = 34.7 bits (76), Expect = 2.5
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 115 FLNRLELPEGETGPAAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGK 174
FL ++ E + P ++ +TY +PI D V +LV+ +A SK+GYR+G
Sbjct: 75 FLPKVIKNEIKYCPYHYNDQLALGAFKTY-EPIN-NDCVIPELVITPGLAFSKDGYRLGY 132
Query: 175 GRGYGD 180
G+G+ D
Sbjct: 133 GKGHFD 138
>UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Mannheimia haemolytica PHL213
Length = 192
Score = 34.7 bits (76), Expect = 2.5
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 10/73 (13%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
L+++ VA K G R+G G G+ D H+ + V H+CQ + LP E
Sbjct: 125 LEMIFTPLVACDKAGNRLGMGGGFYDRTLAQAPHL-------ISVGLAHECQQVEQLPIE 177
Query: 215 LFGPHDVPIDIIV 227
+ D+P+D I+
Sbjct: 178 SW---DMPLDHII 187
>UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 175
Score = 34.7 bits (76), Expect = 2.5
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 11/73 (15%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
DL+++ VA SK+G R+G G G+ D + H K + +D Q+ ++LP E
Sbjct: 113 DLIIVPGVAFSKKGERLGYGGGFYD---RFLEHHK-----VYTIGVAYDFQIMNSLPTE- 163
Query: 216 FGPHDVPIDIIVT 228
HD ++ I+T
Sbjct: 164 --EHDRKLNEIIT 174
>UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Thermosinus carboxydivorans Nor1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Thermosinus
carboxydivorans Nor1
Length = 197
Score = 34.7 bits (76), Expect = 2.5
Identities = 43/143 (30%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 87 DKPQEPVRVI-CLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGK 145
D+PQ +I L+ KT+ VPV Q G + + G R + R K
Sbjct: 58 DEPQTDAIIIDALKTDKTVCVPVLGQQYGIMEAAVI-SGLDDLVTGRLGL-RMPDPACAK 115
Query: 146 PIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDC 205
I D +DLV + VA +EG R+G G GY D F L ++A+ V
Sbjct: 116 NI---DPARIDLVFVPGVAFDREGNRLGMGAGYYD-RF-LTRALQAL-----FVGMAWSF 165
Query: 206 QVFDTLPAELFGPHDVPIDIIVT 228
QV D +PA HD+ ++ ++T
Sbjct: 166 QVADAVPA---ATHDISMNYLLT 185
>UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 205
Score = 34.7 bits (76), Expect = 2.5
Identities = 20/77 (25%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
+T LD++++ + SK G R+G+G+GY D + + KP ++ Q++D
Sbjct: 124 NTGGLDVILVPGLGFSKNGQRLGRGKGYYDNYIQKCIELCHKKPH--LIGLAFSTQMYDQ 181
Query: 211 LPAELFGPHDVPIDIIV 227
+P +D+ +D +V
Sbjct: 182 VPVT---ENDMTLDHVV 195
>UniRef50_A3B6X0 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 738
Score = 34.3 bits (75), Expect = 3.3
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 13 TPTAVDNTKKPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKG--AQEAAAK 69
+P+A L E++T R V R +++NG+A F +++ PN G AQEA A+
Sbjct: 22 SPSAPSAAAHSLTEDITTTKCRAAVRRLMDSNGVAAFDVVLHDGSPNVGGAWAQEATAQ 80
>UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to
5-formyltetrahydrofolate cyclo-ligase
(5,10-methenyl-tetrahydrofolate synthetase)
(Methenyl-THF synthetase) (MTHFS); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
5-formyltetrahydrofolate cyclo-ligase
(5,10-methenyl-tetrahydrofolate synthetase)
(Methenyl-THF synthetase) (MTHFS) - Tribolium castaneum
Length = 197
Score = 33.9 bits (74), Expect = 4.4
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTL 211
T LD VV+ V + +G R+G G GY D + + + P +V Q+ D L
Sbjct: 124 TGGLDFVVVPGVGFTAKGLRLGHGGGYYDRYMADLRKNQDVPP--ALVGLAFKEQICDDL 181
Query: 212 P-AELFGPHDVPIDIIVTP 229
P EL DV ID+++ P
Sbjct: 182 PVTEL----DVQIDLVLFP 196
>UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=1; Erythrobacter litoralis HTCC2594|Rep:
Possible 5-formyltetrahydrofolate cyclo-ligase -
Erythrobacter litoralis (strain HTCC2594)
Length = 180
Score = 33.9 bits (74), Expect = 4.4
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 12/86 (13%)
Query: 149 IEDTVSL--DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQ 206
+ED L D +++ + + G R+G+G G+ D L H K + D Q
Sbjct: 101 VEDAPRLEPDCLLIPLIGFTATGERLGQGGGHYDQ--WLADHQGRTK-----IGLAWDVQ 153
Query: 207 VFDTLPAELFGPHDVPIDIIVTPTQV 232
+ ++LP E PHD +D +VTPT++
Sbjct: 154 LVESLPIE---PHDQRLDAVVTPTRL 176
>UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Actinobacillus succinogenes 130Z
Length = 189
Score = 33.9 bits (74), Expect = 4.4
Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LD++ VA K+G R+G G G+ D H K + + V H CQ D LP E
Sbjct: 123 LDIIFTPLVAFDKQGNRLGMGGGFYDRTL-QDWHEK----NFIAVGLAHQCQQVDELPVE 177
Query: 215 LFGPHDVPI-DII 226
+ D+P+ DI+
Sbjct: 178 NW---DIPLFDIL 187
>UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium cellulolyticum H10|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
cellulolyticum H10
Length = 182
Score = 33.9 bits (74), Expect = 4.4
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 9/80 (11%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPA 213
S+D+V++ A R+G G GY D +K I + + V D Q+ +P
Sbjct: 112 SIDVVIVPGCAFDLNRNRMGYGAGYYD------RFLKLISHNCLKVGIAFDFQIMGKIPC 165
Query: 214 ELFGPHDVPIDIIVTPTQVI 233
D+P+DI++T ++I
Sbjct: 166 NEL---DIPMDILITEERII 182
>UniRef50_Q92HS7 Cluster: Similarity to 5-formyltetrahydrofolate
cyclo-ligase [EC:6.3.3.2]; n=8; Rickettsia|Rep:
Similarity to 5-formyltetrahydrofolate cyclo-ligase
[EC:6.3.3.2] - Rickettsia conorii
Length = 196
Score = 33.5 bits (73), Expect = 5.8
Identities = 18/40 (45%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 141 ETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGD 180
+TY +PI D +LV++ +A SKEGYR+G G+G+ D
Sbjct: 120 KTY-EPIN-NDFFIPELVIIPGLAFSKEGYRLGYGQGHFD 157
>UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep:
All4825 protein - Anabaena sp. (strain PCC 7120)
Length = 193
Score = 33.5 bits (73), Expect = 5.8
Identities = 14/30 (46%), Positives = 21/30 (70%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGD 180
D +DL+++ SVA + +GYR+G G GY D
Sbjct: 116 DPEEVDLILVPSVACNYQGYRLGYGGGYYD 145
>UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Fusobacterium nucleatum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Fusobacterium
nucleatum subsp. nucleatum
Length = 181
Score = 33.5 bits (73), Expect = 5.8
Identities = 23/90 (25%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 145 KPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHD 204
+P G E S+D+++ VA ++ R+G GRGY D F +P+ + +
Sbjct: 101 EPDGEEYKGSIDVIITPGVAFDRDKNRVGFGRGYYDRFF-------VKQPNAKKIAIAFE 153
Query: 205 CQVFDTLPAELFGPHDVPIDIIVTPTQVIE 234
Q+ D +D +DI++T ++I+
Sbjct: 154 KQIID--EGIETDKYDKKVDILITEDEIIK 181
>UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Bacillus clausii KSM-K16|Rep:
5-formyltetrahydrofolate cyclo-ligase - Bacillus clausii
(strain KSM-K16)
Length = 187
Score = 33.5 bits (73), Expect = 5.8
Identities = 26/78 (33%), Positives = 40/78 (51%), Gaps = 11/78 (14%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
L+L+V+ VA +K G R+G G G+ D + + TV + Q+F LP E
Sbjct: 118 LELIVVPGVAFTKAGKRLGLGGGFYD------RFLPSCSGLTVALCFRE--QLFSDLPTE 169
Query: 215 LFGPHDVPIDIIVTPTQV 232
PHDV ID +++ +V
Sbjct: 170 ---PHDVLIDKVISDDRV 184
>UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetase,
putative; n=1; Treponema pallidum|Rep:
5,10-methenyltetrahydrofolate synthetase, putative -
Treponema pallidum
Length = 225
Score = 33.5 bits (73), Expect = 5.8
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 157 LVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAELF 216
L+V+ ++A S G R+G+G G+ D F + + DCQ+ +P E
Sbjct: 139 LIVVPALAFSTNGARLGRGGGHYD-RFLARIAATIPAGSYYTLGLCFDCQIMAVIPQE-- 195
Query: 217 GPHDVPIDIIVTPTQVI 233
HD + ++T T++I
Sbjct: 196 -AHDQSVHAVLTETRLI 211
>UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=5; canis group|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Ehrlichia chaffeensis str. Sapulpa
Length = 180
Score = 33.5 bits (73), Expect = 5.8
Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 9/82 (10%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
++V +++++ +A K R+G G GY D + +KP+ V+ +D Q+ D
Sbjct: 104 NSVIPNILIVPLIAFDKCLNRLGFGGGYYDNT------ISKLKPNCKVIGVAYDIQLCDI 157
Query: 211 LPAELFGPHDVPIDIIVTPTQV 232
+P E HD +D+++T +V
Sbjct: 158 VPTE---SHDQILDMVITEKKV 176
>UniRef50_A5FXW4 Cluster: Putative uncharacterized protein; n=1;
Acidiphilium cryptum JF-5|Rep: Putative uncharacterized
protein - Acidiphilium cryptum (strain JF-5)
Length = 628
Score = 33.5 bits (73), Expect = 5.8
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 129 AAIRKAVSRNGMETYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMH 188
A R +V R GM GKP GI +L ++ ++ + G G GD + + +H
Sbjct: 410 AKARVSVDREGMTVDGKPAGIPGPAALRQAIVKAIFATAPGNTPQAVSGPGDSYYAIAVH 469
Query: 189 MKAIKP 194
+ IKP
Sbjct: 470 -RIIKP 474
>UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Prosthecochloris vibrioformis DSM 265|Rep:
5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
vibrioformis DSM 265
Length = 200
Score = 33.5 bits (73), Expect = 5.8
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 151 DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDT 210
D LD V++ VAV + G R+G G+GY D F + + +P + + Q+ D
Sbjct: 114 DESRLDAVLLPLVAVDRCGRRLGFGKGYYD-RFLSRLSREGFRPWR--IGYAYSFQMTDC 170
Query: 211 LPAELFGPHDVPIDIIVTPTQVI 233
+P++ P D +DI+V V+
Sbjct: 171 IPSD---PWDQNLDILVHERGVV 190
>UniRef50_A1AXM1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Bacteria|Rep: 5-formyltetrahydrofolate cyclo-ligase
- Ruthia magnifica subsp. Calyptogena magnifica
Length = 185
Score = 33.5 bits (73), Expect = 5.8
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
++++ M V K RIG G G+ D + K + + DCQ L A
Sbjct: 109 INIIFMPLVGFDKNKNRIGMGGGFYDRTLTFKKPQQNYK-NPKLYGLAFDCQKVYRLNAN 167
Query: 215 LFGPHDVPIDIIVTPTQV 232
P DVP++ I+TPT +
Sbjct: 168 ---PWDVPLNAIITPTAI 182
>UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanospirillum hungatei JF-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 193
Score = 33.5 bits (73), Expect = 5.8
Identities = 30/99 (30%), Positives = 43/99 (43%), Gaps = 16/99 (16%)
Query: 145 KPIGIE---DTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
+P+G E D + ++ + + G RIG G GY D H+K I
Sbjct: 103 EPVGCELPADPHHVTCAIIPMLGFDRSGGRIGYGAGYYDRFLSEHPHIKRI-------GV 155
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQ 240
+ Q T+P + HD+ +DIIVT T T R SQ
Sbjct: 156 AYSVQEVPTIPVQ---DHDIRMDIIVTET---STYRCSQ 188
>UniRef50_A3H8G1 Cluster: DNA topoisomerase; n=1; Caldivirga
maquilingensis IC-167|Rep: DNA topoisomerase -
Caldivirga maquilingensis IC-167
Length = 610
Score = 33.5 bits (73), Expect = 5.8
Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
Query: 13 TPTAVDNTKKPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKL-A 71
TP ++ L E K K+ +E NG + + ++ N K AQEA +++ A
Sbjct: 207 TPVLNLVVQRALERENFKPEVYYKIKLIIEANGELIELESI-DKFKNLKEAQEALSRVKA 265
Query: 72 ELDVFKN--ANTVKVNPDKPQEPVRVICLEQQKTLYVPVPRLQT 113
V KN A V VNP KP E V LE++ + ++ + QT
Sbjct: 266 GKAVVKNIEAKRVHVNPPKPLETVE---LERRASRFLNIRSKQT 306
>UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1;
Buchnera aphidicola (Schizaphis graminum)|Rep:
Uncharacterized protein BUsg_396 - Buchnera aphidicola
subsp. Schizaphis graminum
Length = 199
Score = 33.5 bits (73), Expect = 5.8
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 8/78 (10%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
LDL+++ VA G R+G G G+ D +F K P + +D Q + +P +
Sbjct: 124 LDLIIVPLVAFDCRGVRLGMGGGFYD-QFLKNWERKKFIP----IGMAYDFQFVNYIPRQ 178
Query: 215 LFGPHDVPIDIIVTPTQV 232
P D+ + I++TP ++
Sbjct: 179 ---PWDISLPIVLTPNKI 193
>UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein
Rgryl_01000426; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000426 - Rickettsiella
grylli
Length = 195
Score = 33.1 bits (72), Expect = 7.7
Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 154 SLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMH-MKAIKPDTVVVTTVHDCQVFDTLP 212
++DLV + + +++G R+G+G G+ D F ++H + +P ++ ++ Q
Sbjct: 115 AIDLVFVPLLGFTEKGQRLGRGAGFYDKSFSFLLHPPRPSRP--FLLGLAYEWQKLTNFT 172
Query: 213 AELFGPHDVPIDIIVTPTQV 232
+ + DVP++ I+T Q+
Sbjct: 173 DKSW---DVPLNAIITEKQI 189
>UniRef50_Q89U90 Cluster: Blr1527 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr1527 protein - Bradyrhizobium
japonicum
Length = 244
Score = 33.1 bits (72), Expect = 7.7
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 7/79 (8%)
Query: 156 DLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAEL 215
D+++ A + G+RIG G G+ D F H++ K V + Q + +PA
Sbjct: 161 DIMLTPLAAFDRLGHRIGYGAGHYDFTFA---HLRKTK-QIVGIGLAFAAQEIEAVPAL- 215
Query: 216 FGPHDVPIDIIVTPTQVIE 234
HDV +D ++T + V +
Sbjct: 216 --SHDVALDYVLTESDVFD 232
>UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Hyphomonas neptunium ATCC
15444|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Hyphomonas neptunium (strain ATCC 15444)
Length = 207
Score = 33.1 bits (72), Expect = 7.7
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 153 VSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLP 212
V+ LV+ +A G R+G GRG+ D + ++A K + Q D +P
Sbjct: 112 VTPTLVLTPLLAYDTLGNRLGYGRGHYD---AALEKLRA-KGRAFACAIAYAAQQIDKVP 167
Query: 213 AELFGPHDVPIDIIVTPTQVIETQRMSQR 241
E PHD P+D +TP + M R
Sbjct: 168 CE---PHDQPLDWAITPIGSVPLFMMRNR 193
>UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 199
Score = 33.1 bits (72), Expect = 7.7
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 9/74 (12%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQVFDTLPAE 214
+D+ ++ +A + RIG G+GY D +K + P + V + Q +P+E
Sbjct: 114 IDVCIIPLLAFDQNLNRIGFGKGYYD------RFLKEVGPSCLKVGVAYHFQKVPKIPSE 167
Query: 215 LFGPHDVPIDIIVT 228
HDV +D+IVT
Sbjct: 168 ---RHDVKLDVIVT 178
>UniRef50_A3T1K0 Cluster: Putative uncharacterized protein; n=2;
Sulfitobacter|Rep: Putative uncharacterized protein -
Sulfitobacter sp. NAS-14.1
Length = 886
Score = 33.1 bits (72), Expect = 7.7
Identities = 25/69 (36%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 25 PEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKV 84
PE++ +Q+ R + + N LA F RP K A AAAK AE+D A +
Sbjct: 686 PEDLPEQNERANLGG-VTRNELAAF-RPTLRSADVIKAA--AAAKQAEVDAAAEAAAAAI 741
Query: 85 NPDKPQEPV 93
PQEPV
Sbjct: 742 KAALPQEPV 750
>UniRef50_A0PYT7 Cluster: Leucine Rich Repeat domain protein; n=4;
cellular organisms|Rep: Leucine Rich Repeat domain
protein - Clostridium novyi (strain NT)
Length = 906
Score = 33.1 bits (72), Expect = 7.7
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 19 NTKKPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAEL--DVF 76
N K LP+ + + +K +LE N L P+ V++++PN + A + L DVF
Sbjct: 476 NKIKELPDGIFDKLVNLKKV-YLERNKLETLPKGVFDKLPNLETVVLATNNIKHLDDDVF 534
Query: 77 KNANTVK 83
KN +K
Sbjct: 535 KNNKKLK 541
>UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-like
protein; n=10; Magnoliophyta|Rep:
5-formyltetrahydrofolate cyclo-ligase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 287
Score = 33.1 bits (72), Expect = 7.7
Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 10/148 (6%)
Query: 101 QKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYG--KPIGIEDTVSLDLV 158
QK LYVP + + L + E A + ++ G + ++ +DL
Sbjct: 90 QKKLYVPWVEDKNSNMRMLHISHMEDLVANSMNILEPAPVDAQGNDREDVLQADEPIDLF 149
Query: 159 VMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIK--PDTVVVTTVHDCQVFD--TLPAE 214
++ +A + G R+G+G GY D K ++V + Q+ + ++P
Sbjct: 150 ILPGLAFDRCGRRLGRGGGYYDTFLKRYQDRAKEKGWRYPLMVALSYSPQILEDGSIPVT 209
Query: 215 LFGPHDVPIDIIVTPTQVIE-TQRMSQR 241
P+DV ID +VTP+ V+ T R ++R
Sbjct: 210 ---PNDVLIDALVTPSGVVPITPRATER 234
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.137 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 315,713,837
Number of Sequences: 1657284
Number of extensions: 13700244
Number of successful extensions: 28288
Number of sequences better than 10.0: 182
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 131
Number of HSP's that attempted gapping in prelim test: 28101
Number of HSP's gapped (non-prelim): 189
length of query: 270
length of database: 575,637,011
effective HSP length: 99
effective length of query: 171
effective length of database: 411,565,895
effective search space: 70377768045
effective search space used: 70377768045
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 72 (33.1 bits)
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