Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002295-TA|BGIBMGA002295-PA|IPR002698|5-
formyltetrahydrofolate cyclo-ligase
(270 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC112059-1|AAI12060.1| 383|Homo sapiens methenyltetrahydrofolat... 242 8e-64
BC112057-1|AAI12058.1| 383|Homo sapiens methenyltetrahydrofolat... 242 8e-64
AK023060-1|BAB14383.1| 371|Homo sapiens protein ( Homo sapiens ... 242 8e-64
AK023955-1|BAB14739.1| 382|Homo sapiens protein ( Homo sapiens ... 242 1e-63
L38928-1|AAC41945.1| 203|Homo sapiens 5,10-methenyltetrahydrofo... 36 0.11
BC019921-1|AAH19921.1| 203|Homo sapiens 5,10-methenyltetrahydro... 36 0.11
BC012417-1|AAH12417.1| 193|Homo sapiens MTHFS protein protein. 36 0.11
BC037852-1|AAH37852.1| 94|Homo sapiens MTHFS protein protein. 36 0.20
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 30 7.4
BC031222-1|AAH31222.1| 429|Homo sapiens serum response factor b... 30 7.4
BC017102-1|AAH17102.1| 314|Homo sapiens SRFBP1 protein protein. 30 7.4
AY611630-1|AAU25829.2| 429|Homo sapiens SRF-dependent transcrip... 30 7.4
AK058015-1|BAB71631.1| 427|Homo sapiens protein ( Homo sapiens ... 30 7.4
>BC112059-1|AAI12060.1| 383|Homo sapiens methenyltetrahydrofolate
synthetase domain containing protein.
Length = 383
Score = 242 bits (593), Expect = 8e-64
Identities = 117/244 (47%), Positives = 162/244 (66%), Gaps = 2/244 (0%)
Query: 22 KPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANT 81
+P V+KQ R ++W ++E+ LA FPRPV++RIPNFKG+ A + +LDVF
Sbjct: 2 EPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQE 61
Query: 82 VKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGME 141
VKV+PDKP E VR++ L+ +KTL VP PRL+TG N++ P G T +RK + G+
Sbjct: 62 VKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVR 120
Query: 142 TYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
Y PIG++ V +DLVV+GSVAVS++G+RIGKG GY DLE+ +M+ M A+ +T VVT
Sbjct: 121 NYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTI 180
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPIL 261
VHDCQV D +P EL HD+ +D I+TPT+VI T +P GI W +S ++ +PIL
Sbjct: 181 VHDCQVVD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPIL 239
Query: 262 GQLR 265
LR
Sbjct: 240 RSLR 243
>BC112057-1|AAI12058.1| 383|Homo sapiens methenyltetrahydrofolate
synthetase domain containing protein.
Length = 383
Score = 242 bits (593), Expect = 8e-64
Identities = 117/244 (47%), Positives = 162/244 (66%), Gaps = 2/244 (0%)
Query: 22 KPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANT 81
+P V+KQ R ++W ++E+ LA FPRPV++RIPNFKG+ A + +LDVF
Sbjct: 2 EPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQE 61
Query: 82 VKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGME 141
VKV+PDKP E VR++ L+ +KTL VP PRL+TG N++ P G T +RK + G+
Sbjct: 62 VKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVR 120
Query: 142 TYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
Y PIG++ V +DLVV+GSVAVS++G+RIGKG GY DLE+ +M+ M A+ +T VVT
Sbjct: 121 NYSVPIGLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTI 180
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPIL 261
VHDCQV D +P EL HD+ +D I+TPT+VI T +P GI W +S ++ +PIL
Sbjct: 181 VHDCQVVD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPIL 239
Query: 262 GQLR 265
LR
Sbjct: 240 RSLR 243
>AK023060-1|BAB14383.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ12998 fis, clone NT2RP3000267. ).
Length = 371
Score = 242 bits (593), Expect = 8e-64
Identities = 117/244 (47%), Positives = 162/244 (66%), Gaps = 2/244 (0%)
Query: 22 KPLPEEVTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANT 81
+P V+KQ R ++W ++E+ LA FPRPV++RIPNFKG+ A + +LDVF A
Sbjct: 2 EPRAVGVSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARAQE 61
Query: 82 VKVNPDKPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGME 141
VKV+PDKP E VR++ L+ +KTL VP PRL+TG N++ P G T +RK + G+
Sbjct: 62 VKVDPDKPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVR 120
Query: 142 TYGKPIGIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTT 201
Y PIG++ V +DLVV+GSVA S++G+RIGKG GY DLE+ +M+ M A+ +T VVT
Sbjct: 121 NYSVPIGLDSRVLVDLVVVGSVAASEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTI 180
Query: 202 VHDCQVFDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPIL 261
VHDCQV D +P EL HD+ +D I+TPT+VI T +P GI W +S ++ +PIL
Sbjct: 181 VHDCQVVD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPIL 239
Query: 262 GQLR 265
LR
Sbjct: 240 RSLR 243
>AK023955-1|BAB14739.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ13893 fis, clone THYRO1001661. ).
Length = 382
Score = 242 bits (592), Expect = 1e-63
Identities = 116/238 (48%), Positives = 160/238 (67%), Gaps = 2/238 (0%)
Query: 28 VTKQSYRVKVWRHLETNGLAVFPRPVYNRIPNFKGAQEAAAKLAELDVFKNANTVKVNPD 87
V+KQ R ++W ++E+ LA FPRPV++RIPNFKG+ A + +LDVF VKV+PD
Sbjct: 7 VSKQDIREQIWGYMESQNLADFPRPVHHRIPNFKGSYLACQNIKDLDVFARTQEVKVDPD 66
Query: 88 KPQEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGMETYGKPI 147
KP E VR++ L+ +KTL VP PRL+TG N++ P G T +RK + G+ Y PI
Sbjct: 67 KPLEGVRLLVLQSKKTLLVPTPRLRTGLFNKITPPPGAT-KDILRKCATSQGVRNYSVPI 125
Query: 148 GIEDTVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVVTTVHDCQV 207
G++ V +DLVV+GSVAVS++G+RIGKG GY DLE+ +M+ M A+ +T VVT VHDCQV
Sbjct: 126 GLDSRVLVDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKETPVVTIVHDCQV 185
Query: 208 FDTLPAELFGPHDVPIDIIVTPTQVIETQRMSQRPTGILWHLLSNRRLQLMPILGQLR 265
D +P EL HD+ +D I+TPT+VI T +P GI W +S ++ +PIL LR
Sbjct: 186 VD-IPEELVEEHDITVDYILTPTRVIATGCKRPKPMGITWFKISLEMMEKIPILRSLR 242
>L38928-1|AAC41945.1| 203|Homo sapiens
5,10-methenyltetrahydrofolate synthetase protein.
Length = 203
Score = 36.3 bits (80), Expect = 0.11
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
T LDL+ M + K G R+G+G+GY D + + +KP T+ +
Sbjct: 126 TGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLAL 173
>BC019921-1|AAH19921.1| 203|Homo sapiens
5,10-methenyltetrahydrofolate synthetase
(5-formyltetrahydrofolate cyclo-ligase protein.
Length = 203
Score = 36.3 bits (80), Expect = 0.11
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
T LDL+ M + K G R+G+G+GY D + + +KP T+ +
Sbjct: 126 TGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLAL 173
>BC012417-1|AAH12417.1| 193|Homo sapiens MTHFS protein protein.
Length = 193
Score = 36.3 bits (80), Expect = 0.11
Identities = 16/48 (33%), Positives = 26/48 (54%)
Query: 152 TVSLDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
T LDL+ M + K G R+G+G+GY D + + +KP T+ +
Sbjct: 116 TGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLAL 163
>BC037852-1|AAH37852.1| 94|Homo sapiens MTHFS protein protein.
Length = 94
Score = 35.5 bits (78), Expect = 0.20
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 155 LDLVVMGSVAVSKEGYRIGKGRGYGDLEFGLMMHMKAIKPDTVVV 199
LDL+ M + K G R+G+G+GY D + + +KP T+ +
Sbjct: 20 LDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLAL 64
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 30.3 bits (65), Expect = 7.4
Identities = 14/51 (27%), Positives = 24/51 (47%)
Query: 90 QEPVRVICLEQQKTLYVPVPRLQTGFLNRLELPEGETGPAAIRKAVSRNGM 140
Q P +C+++ LY PVP + + P+G + P I +S G+
Sbjct: 52 QMPYTTMCIKEALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGL 102
>BC031222-1|AAH31222.1| 429|Homo sapiens serum response factor
binding protein 1 protein.
Length = 429
Score = 30.3 bits (65), Expect = 7.4
Identities = 15/43 (34%), Positives = 23/43 (53%)
Query: 61 KGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKT 103
K + K+A+++ A T+ +P KP E V+ LE QKT
Sbjct: 179 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKT 221
>BC017102-1|AAH17102.1| 314|Homo sapiens SRFBP1 protein protein.
Length = 314
Score = 30.3 bits (65), Expect = 7.4
Identities = 15/43 (34%), Positives = 23/43 (53%)
Query: 61 KGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKT 103
K + K+A+++ A T+ +P KP E V+ LE QKT
Sbjct: 64 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKT 106
>AY611630-1|AAU25829.2| 429|Homo sapiens SRF-dependent
transcription regulation associated protein protein.
Length = 429
Score = 30.3 bits (65), Expect = 7.4
Identities = 15/43 (34%), Positives = 23/43 (53%)
Query: 61 KGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKT 103
K + K+A+++ A T+ +P KP E V+ LE QKT
Sbjct: 179 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKT 221
>AK058015-1|BAB71631.1| 427|Homo sapiens protein ( Homo sapiens
cDNA FLJ25286 fis, clone STM06909. ).
Length = 427
Score = 30.3 bits (65), Expect = 7.4
Identities = 15/43 (34%), Positives = 23/43 (53%)
Query: 61 KGAQEAAAKLAELDVFKNANTVKVNPDKPQEPVRVICLEQQKT 103
K + K+A+++ A T+ +P KP E V+ LE QKT
Sbjct: 179 KPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVVSLESQKT 221
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.137 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,087,928
Number of Sequences: 224733
Number of extensions: 1842519
Number of successful extensions: 2820
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2799
Number of HSP's gapped (non-prelim): 13
length of query: 270
length of database: 73,234,838
effective HSP length: 89
effective length of query: 181
effective length of database: 53,233,601
effective search space: 9635281781
effective search space used: 9635281781
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 64 (29.9 bits)
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