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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA002293-TA|BGIBMGA002293-PA|undefined
         (504 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AK074405-1|BAB85072.1|  478|Homo sapiens protein ( Homo sapiens ...   134   5e-31
BC018205-1|AAH18205.2|  394|Homo sapiens HEXDC protein protein.        91   6e-18
BC035561-1|AAH35561.1|  493|Homo sapiens hexosaminidase (glycosy...    91   8e-18
AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic fact...    32   5.4  
AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic fact...    32   5.4  
AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic fact...    32   5.4  
AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitami...    32   5.4  
AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12 re...    32   5.4  
AB209880-1|BAD93117.1| 1327|Homo sapiens cubilin variant protein.      32   5.4  

>AK074405-1|BAB85072.1|  478|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23825 fis, clone HUV00659. ).
          Length = 478

 Score =  134 bits (325), Expect = 5e-31
 Identities = 64/126 (50%), Positives = 87/126 (69%)

Query: 53  VVHLDLKGSPPSLNYLEDLLPVLKKHGANGLLVEYEDMFPYEGRLVNLRAKNCYDKIELQ 112
           +VHLDLKG+PP ++YL ++ P+ +  GANGLL+EYEDMFPYEG L  LRAK  Y   E++
Sbjct: 3   LVHLDLKGAPPKVSYLSEIFPLFRALGANGLLIEYEDMFPYEGPLRLLRAKYAYSPSEIK 62

Query: 113 RFLRGAIELGFEIIPLIQTFGHMEFVLKQKEFYHLREDPTYPDSICPTKIESQMLIKEML 172
             L  A     E+IPL+QTFGHMEFVLK   F HLRE  ++P ++ P + ES  L+  M+
Sbjct: 63  EILHLAGLNELEVIPLVQTFGHMEFVLKHTAFAHLREVGSFPCTLNPHEAESLALVGAMI 122

Query: 173 IQIKQI 178
            Q+ ++
Sbjct: 123 DQVLEL 128



 Score = 91.5 bits (217), Expect = 6e-18
 Identities = 50/126 (39%), Positives = 67/126 (53%), Gaps = 9/126 (7%)

Query: 184 PETTVLIWDDMFRSIKLKSWNEIGYFNKIQTVYWDYGANSSVSHVNLL--KYHR-KFDNI 240
           P  T L+WDDM R +        G    ++ V WDY A+  V    LL  KY R  F  +
Sbjct: 182 PSVTPLVWDDMLRDLPEDQLAASGVPQLVEPVLWDYTADLDVHGKVLLMQKYRRCGFPQL 241

Query: 241 WIATAFKGADGRLSTIPNLKNRFLNHLSWLKLIANYKFGGETNFHSFVGIILTGWSRYSH 300
           W A+AFKGA G    +P +++   NH+ WL++  +    G T+  S  GIILTGW RY H
Sbjct: 242 WAASAFKGATGPSQAVPPVEHHLRNHVQWLQVAGS----GPTD--SLQGIILTGWQRYDH 295

Query: 301 FDPLCE 306
           +  LCE
Sbjct: 296 YSVLCE 301


>BC018205-1|AAH18205.2|  394|Homo sapiens HEXDC protein protein.
          Length = 394

 Score = 91.5 bits (217), Expect = 6e-18
 Identities = 50/126 (39%), Positives = 67/126 (53%), Gaps = 9/126 (7%)

Query: 184 PETTVLIWDDMFRSIKLKSWNEIGYFNKIQTVYWDYGANSSVSHVNLL--KYHR-KFDNI 240
           P  T L+WDDM R +        G    ++ V WDY A+  V    LL  KY R  F  +
Sbjct: 98  PSVTPLVWDDMLRDLPEDQLAASGVPQLVEPVLWDYTADLDVHGKVLLMQKYRRCGFPQL 157

Query: 241 WIATAFKGADGRLSTIPNLKNRFLNHLSWLKLIANYKFGGETNFHSFVGIILTGWSRYSH 300
           W A+AFKGA G    +P +++   NH+ WL++  +    G T+  S  GIILTGW RY H
Sbjct: 158 WAASAFKGATGPSQAVPPVEHHLRNHVQWLQVAGS----GPTD--SLQGIILTGWQRYDH 211

Query: 301 FDPLCE 306
           +  LCE
Sbjct: 212 YSVLCE 217



 Score = 38.3 bits (85), Expect = 0.063
 Identities = 18/44 (40%), Positives = 28/44 (63%)

Query: 135 MEFVLKQKEFYHLREDPTYPDSICPTKIESQMLIKEMLIQIKQI 178
           MEFVLK   F HLRE  ++P ++ P + ES  L+  M+ Q+ ++
Sbjct: 1   MEFVLKHTAFAHLREVGSFPCTLNPHEAESLALVGAMIDQVLEL 44


>BC035561-1|AAH35561.1|  493|Homo sapiens hexosaminidase (glycosyl
           hydrolase family 20, catalytic domain) containing
           protein.
          Length = 493

 Score = 91.1 bits (216), Expect = 8e-18
 Identities = 50/126 (39%), Positives = 67/126 (53%), Gaps = 9/126 (7%)

Query: 184 PETTVLIWDDMFRSIKLKSWNEIGYFNKIQTVYWDYGANSSVSHVNLL--KYHR-KFDNI 240
           P  T L+WDDM R +        G    ++ V WDY A+  V    LL  KY R  F  +
Sbjct: 98  PSVTPLVWDDMLRDLPEDQLAASGVPQLVEPVLWDYTADLDVYGKVLLMQKYRRCGFPQL 157

Query: 241 WIATAFKGADGRLSTIPNLKNRFLNHLSWLKLIANYKFGGETNFHSFVGIILTGWSRYSH 300
           W A+AFKGA G    +P +++   NH+ WL++  +    G T+  S  GIILTGW RY H
Sbjct: 158 WAASAFKGATGPSQAVPPVEHHLRNHVQWLQVAGS----GPTD--SLQGIILTGWQRYDH 211

Query: 301 FDPLCE 306
           +  LCE
Sbjct: 212 YSVLCE 217



 Score = 38.3 bits (85), Expect = 0.063
 Identities = 18/44 (40%), Positives = 28/44 (63%)

Query: 135 MEFVLKQKEFYHLREDPTYPDSICPTKIESQMLIKEMLIQIKQI 178
           MEFVLK   F HLRE  ++P ++ P + ES  L+  M+ Q+ ++
Sbjct: 1   MEFVLKHTAFAHLREVGSFPCTLNPHEAESLALVGAMIDQVLEL 44


>AL731551-1|CAI40246.1| 3623|Homo sapiens cubilin (intrinsic
            factor-cobalamin receptor) protein.
          Length = 3623

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348  YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
            Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 1420 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 1452


>AL596445-1|CAH72450.1| 3623|Homo sapiens cubilin (intrinsic
            factor-cobalamin receptor) protein.
          Length = 3623

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348  YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
            Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 1420 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 1452


>AL365215-1|CAH73630.1| 3623|Homo sapiens cubilin (intrinsic
            factor-cobalamin receptor) protein.
          Length = 3623

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348  YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
            Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 1420 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 1452


>AF243129-1|AAK61830.1| 3494|Homo sapiens intrinsic factor-vitamin B12
            receptor protein.
          Length = 3494

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348  YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
            Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 1291 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 1323


>AF034611-1|AAC82612.1| 3623|Homo sapiens intrinsic factor-B12
            receptor precursor protein.
          Length = 3623

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348  YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
            Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 1420 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 1452


>AB209880-1|BAD93117.1| 1327|Homo sapiens cubilin variant protein.
          Length = 1327

 Score = 31.9 bits (69), Expect = 5.4
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 348 YLQTDFSDSLHCVIHDIEKTNYSPCIFDGCELY 380
           Y++TD   S+   IHD +   +S C FD  E+Y
Sbjct: 126 YIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIY 158


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.324    0.141    0.428 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,844,415
Number of Sequences: 224733
Number of extensions: 3078149
Number of successful extensions: 5004
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 4986
Number of HSP's gapped (non-prelim): 12
length of query: 504
length of database: 73,234,838
effective HSP length: 93
effective length of query: 411
effective length of database: 52,334,669
effective search space: 21509548959
effective search space used: 21509548959
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 67 (31.1 bits)

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