Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002270-TA|BGIBMGA002270-PA|IPR001128|Cytochrome P450
(246 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 111 2e-24
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 111 2e-24
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 111 2e-24
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 111 2e-24
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 97 5e-20
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 97 5e-20
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 97 5e-20
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 97 5e-20
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 95 2e-19
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 95 2e-19
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 95 3e-19
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 95 3e-19
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 95 3e-19
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 95 3e-19
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 95 3e-19
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 95 3e-19
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 94 5e-19
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 94 5e-19
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 94 5e-19
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 94 5e-19
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 94 5e-19
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 94 5e-19
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 94 5e-19
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 92 1e-18
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 92 1e-18
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 92 1e-18
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 92 1e-18
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 92 1e-18
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 92 1e-18
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 89 1e-17
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 89 1e-17
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 87 5e-17
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 87 5e-17
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 87 5e-17
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 87 5e-17
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 87 7e-17
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 87 7e-17
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 87 7e-17
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 87 7e-17
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 87 7e-17
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 87 7e-17
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 87 7e-17
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 87 7e-17
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 87 7e-17
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 87 7e-17
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 87 7e-17
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 85 2e-16
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 85 2e-16
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 85 2e-16
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 85 2e-16
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 85 2e-16
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 85 2e-16
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 85 2e-16
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 85 2e-16
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 85 2e-16
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 85 2e-16
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 85 2e-16
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 85 2e-16
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 85 2e-16
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 85 2e-16
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 85 2e-16
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 85 2e-16
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 85 2e-16
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 84 4e-16
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 83 7e-16
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 82 2e-15
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 82 2e-15
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 82 2e-15
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 82 2e-15
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 82 2e-15
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 81 3e-15
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 81 5e-15
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 80 8e-15
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 78 2e-14
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 77 4e-14
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 77 4e-14
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 77 4e-14
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 77 4e-14
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 76 1e-13
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 74 5e-13
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 74 5e-13
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 73 9e-13
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 73 9e-13
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 73 9e-13
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 73 9e-13
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 73 1e-12
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 73 1e-12
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 73 1e-12
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 73 1e-12
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 72 2e-12
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 72 2e-12
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 72 2e-12
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 72 2e-12
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 72 2e-12
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 71 3e-12
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 71 3e-12
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 70 9e-12
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 69 1e-11
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 69 1e-11
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 69 1e-11
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 69 1e-11
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 69 2e-11
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 69 2e-11
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 69 2e-11
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 69 2e-11
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 69 2e-11
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 67 6e-11
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 67 6e-11
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 67 6e-11
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 66 8e-11
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 66 8e-11
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 66 8e-11
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 66 8e-11
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 66 8e-11
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 66 8e-11
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 66 8e-11
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 66 8e-11
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 66 8e-11
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 65 2e-10
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 65 2e-10
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 65 2e-10
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 65 2e-10
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 65 2e-10
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 65 2e-10
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 65 2e-10
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 63 8e-10
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 63 1e-09
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 63 1e-09
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 63 1e-09
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 63 1e-09
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 63 1e-09
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 63 1e-09
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 63 1e-09
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 63 1e-09
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 63 1e-09
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 63 1e-09
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 63 1e-09
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 63 1e-09
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 63 1e-09
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 62 1e-09
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 62 1e-09
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 62 1e-09
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 62 2e-09
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 62 2e-09
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 62 2e-09
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 62 2e-09
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 62 2e-09
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 62 2e-09
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 62 2e-09
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 62 2e-09
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 62 2e-09
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 61 4e-09
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 60 7e-09
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 60 9e-09
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 58 2e-08
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 58 2e-08
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 58 2e-08
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 58 3e-08
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 58 3e-08
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 58 3e-08
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 58 3e-08
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 58 3e-08
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 58 4e-08
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 58 4e-08
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 58 4e-08
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 58 4e-08
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 57 5e-08
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 56 9e-08
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 56 9e-08
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 56 9e-08
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 56 9e-08
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 56 9e-08
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 56 9e-08
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 56 9e-08
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 56 9e-08
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 56 9e-08
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 56 9e-08
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 56 9e-08
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 56 9e-08
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 56 9e-08
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 56 9e-08
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 56 9e-08
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 56 9e-08
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 56 9e-08
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 56 9e-08
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 56 9e-08
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 56 9e-08
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 56 2e-07
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 56 2e-07
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 56 2e-07
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 56 2e-07
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 56 2e-07
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 56 2e-07
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 56 2e-07
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 56 2e-07
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 56 2e-07
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 56 2e-07
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 56 2e-07
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 56 2e-07
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 56 2e-07
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 56 2e-07
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 56 2e-07
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 56 2e-07
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 56 2e-07
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 56 2e-07
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 56 2e-07
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 56 2e-07
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 55 2e-07
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 55 2e-07
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 55 2e-07
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 55 2e-07
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 55 2e-07
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 55 3e-07
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 55 3e-07
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 54 4e-07
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 54 4e-07
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 54 4e-07
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 54 4e-07
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 54 4e-07
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 54 4e-07
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 54 4e-07
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 54 5e-07
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 54 6e-07
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 54 6e-07
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 54 6e-07
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 54 6e-07
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 54 6e-07
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 54 6e-07
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 54 6e-07
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 54 6e-07
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 53 8e-07
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 53 8e-07
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 53 8e-07
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 53 8e-07
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 53 8e-07
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 53 8e-07
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 53 8e-07
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 53 8e-07
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 53 8e-07
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 53 8e-07
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 53 1e-06
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 53 1e-06
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 53 1e-06
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 53 1e-06
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 53 1e-06
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 53 1e-06
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 53 1e-06
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 52 2e-06
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 52 2e-06
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 52 2e-06
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 52 2e-06
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 52 2e-06
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 52 2e-06
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 52 2e-06
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 52 2e-06
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 52 2e-06
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 52 2e-06
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 51 3e-06
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 51 3e-06
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 51 3e-06
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 51 3e-06
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 51 3e-06
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 51 3e-06
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 51 3e-06
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 51 3e-06
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 51 3e-06
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 51 3e-06
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 51 3e-06
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 51 3e-06
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 51 3e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 51 3e-06
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 51 3e-06
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 51 4e-06
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 51 4e-06
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 51 4e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 51 4e-06
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 50 6e-06
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 50 6e-06
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 50 8e-06
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 50 8e-06
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 49 2e-05
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 49 2e-05
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 49 2e-05
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 49 2e-05
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 49 2e-05
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 49 2e-05
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 49 2e-05
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 49 2e-05
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 48 2e-05
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 48 2e-05
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 48 2e-05
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 48 2e-05
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 48 2e-05
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 48 2e-05
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 48 2e-05
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 48 2e-05
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 47 5e-05
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 47 5e-05
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 47 5e-05
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 47 5e-05
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 47 7e-05
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 47 7e-05
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 46 9e-05
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 46 9e-05
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 46 9e-05
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 46 9e-05
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 46 1e-04
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 46 1e-04
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 46 1e-04
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 46 1e-04
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 46 2e-04
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 46 2e-04
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 44 4e-04
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 44 4e-04
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 44 4e-04
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 44 4e-04
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 44 4e-04
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 44 4e-04
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 44 5e-04
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 44 5e-04
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 44 7e-04
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 44 7e-04
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 43 0.001
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 43 0.001
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 43 0.001
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 42 0.002
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 42 0.002
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 42 0.003
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 42 0.003
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 42 0.003
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 42 0.003
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 42 0.003
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 42 0.003
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 42 0.003
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 42 0.003
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 42 0.003
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 42 0.003
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 41 0.005
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 40 0.011
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 39 0.014
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 39 0.019
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 39 0.019
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 39 0.019
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 38 0.033
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 36 0.099
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 36 0.099
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 36 0.099
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 36 0.13
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 36 0.13
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 36 0.13
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 36 0.13
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 36 0.13
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 33 0.70
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 33 0.70
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 33 0.70
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 33 0.70
L29016-1|AAA36448.1| 386|Homo sapiens prostanoid IP receptor pr... 31 3.7
D38127-1|BAA07325.1| 386|Homo sapiens prostacyclin receptor pro... 31 3.7
D29634-1|BAA06110.1| 386|Homo sapiens prostacyclin receptor pro... 31 3.7
D25418-1|BAA05008.1| 386|Homo sapiens prostacyclin receptor pro... 31 3.7
BC112167-1|AAI12168.1| 1429|Homo sapiens mutL homolog 3 (E. coli... 31 3.7
BC110342-1|AAI10343.1| 386|Homo sapiens prostaglandin I2 (prost... 31 3.7
BC075814-1|AAH75814.1| 386|Homo sapiens prostaglandin I2 (prost... 31 3.7
AY963685-1|AAX59030.1| 1429|Homo sapiens mutL 3 homolog (E.coli)... 31 3.7
AY242134-1|AAO92301.1| 386|Homo sapiens prostaglandin I2 (prost... 31 3.7
AF195658-1|AAF23905.1| 1429|Homo sapiens DNA mismatch repair pro... 31 3.7
AF195657-1|AAF23904.1| 1429|Homo sapiens DNA mismatch repair pro... 31 3.7
AB039667-1|BAA92353.1| 1453|Homo sapiens DNA mismatch repair pro... 31 3.7
BC003586-1|AAH03586.1| 308|Homo sapiens ARMC10 protein protein. 30 6.5
AY150854-1|AAN72316.1| 343|Homo sapiens SVH-A protein. 30 6.5
AY150853-1|AAN72315.1| 308|Homo sapiens SVH-B protein. 30 6.5
AK075500-1|BAC11655.1| 343|Homo sapiens protein ( Homo sapiens ... 30 6.5
AC007683-1|AAS07531.1| 212|Homo sapiens unknown protein. 30 6.5
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 111 bits (268), Expect = 2e-24
Identities = 71/237 (29%), Positives = 124/237 (52%), Gaps = 25/237 (10%)
Query: 34 GDGLITS-SERKFKSMLELLLK--DSDGDALTDEEIRDEVDTLILAGSDTSSQLT----- 85
GDG ++ S+ K ++ L+LLL D +G+ L+ E+IR+EVDT + G DT++
Sbjct: 284 GDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLY 343
Query: 86 ---------------VASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPE 130
+ V G SD +L Y E V+KETLRL+P++PL R
Sbjct: 344 LLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS 403
Query: 131 NEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVG 190
+ ++ Y + + V+ Y L+R P + P+ F+PER+ +P A+ FS G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 191 KRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMD--VIMTPSDNCYVDFELR 245
RNCIG+ +A++ K IL+ ++R + + ++ + E ++ +I+ PS+ ++ + R
Sbjct: 464 PRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 22/33 (66%)
Query: 20 LQKHFVYQFASNWLGDGLITSSERKFKSMLELL 52
+ K +Y+F WLG GL+TS+ K++S ++L
Sbjct: 118 IDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKML 150
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 111 bits (268), Expect = 2e-24
Identities = 71/237 (29%), Positives = 124/237 (52%), Gaps = 25/237 (10%)
Query: 34 GDGLITS-SERKFKSMLELLLK--DSDGDALTDEEIRDEVDTLILAGSDTSSQLT----- 85
GDG ++ S+ K ++ L+LLL D +G+ L+ E+IR+EVDT + G DT++
Sbjct: 284 GDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLY 343
Query: 86 ---------------VASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPE 130
+ V G SD +L Y E V+KETLRL+P++PL R
Sbjct: 344 LLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS 403
Query: 131 NEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVG 190
+ ++ Y + + V+ Y L+R P + P+ F+PER+ +P A+ FS G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 191 KRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMD--VIMTPSDNCYVDFELR 245
RNCIG+ +A++ K IL+ ++R + + ++ + E ++ +I+ PS+ ++ + R
Sbjct: 464 PRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 22/33 (66%)
Query: 20 LQKHFVYQFASNWLGDGLITSSERKFKSMLELL 52
+ K +Y+F WLG GL+TS+ K++S ++L
Sbjct: 118 IDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKML 150
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 111 bits (268), Expect = 2e-24
Identities = 71/237 (29%), Positives = 124/237 (52%), Gaps = 25/237 (10%)
Query: 34 GDGLITS-SERKFKSMLELLLK--DSDGDALTDEEIRDEVDTLILAGSDTSSQLT----- 85
GDG ++ S+ K ++ L+LLL D +G+ L+ E+IR+EVDT + G DT++
Sbjct: 262 GDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLY 321
Query: 86 ---------------VASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPE 130
+ V G SD +L Y E V+KETLRL+P++PL R
Sbjct: 322 LLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS 381
Query: 131 NEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVG 190
+ ++ Y + + V+ Y L+R P + P+ F+PER+ +P A+ FS G
Sbjct: 382 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 441
Query: 191 KRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMD--VIMTPSDNCYVDFELR 245
RNCIG+ +A++ K IL+ ++R + + ++ + E ++ +I+ PS+ ++ + R
Sbjct: 442 PRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 498
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 22/33 (66%)
Query: 20 LQKHFVYQFASNWLGDGLITSSERKFKSMLELL 52
+ K +Y+F WLG GL+TS+ K++S ++L
Sbjct: 96 IDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKML 128
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 111 bits (268), Expect = 2e-24
Identities = 71/237 (29%), Positives = 124/237 (52%), Gaps = 25/237 (10%)
Query: 34 GDGLITS-SERKFKSMLELLLK--DSDGDALTDEEIRDEVDTLILAGSDTSSQLT----- 85
GDG ++ S+ K ++ L+LLL D +G+ L+ E+IR+EVDT + G DT++
Sbjct: 284 GDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLY 343
Query: 86 ---------------VASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPE 130
+ V G SD +L Y E V+KETLRL+P++PL R
Sbjct: 344 LLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVS 403
Query: 131 NEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVG 190
+ ++ Y + + V+ Y L+R P + P+ F+PER+ +P A+ FS G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 191 KRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMD--VIMTPSDNCYVDFELR 245
RNCIG+ +A++ K IL+ ++R + + ++ + E ++ +I+ PS+ ++ + R
Sbjct: 464 PRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520
Score = 31.9 bits (69), Expect = 2.1
Identities = 13/33 (39%), Positives = 22/33 (66%)
Query: 20 LQKHFVYQFASNWLGDGLITSSERKFKSMLELL 52
+ K +Y+F WLG GL+TS+ K++S ++L
Sbjct: 118 IDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKML 150
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 97.1 bits (231), Expect = 5e-20
Identities = 64/216 (29%), Positives = 110/216 (50%), Gaps = 23/216 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVASV------C-------- 90
LL +D DG L+DE+IR E DT + G DT+S +A C
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 91 -GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
G +++E +L +T +KE+LR YP + LV R+ +IKL + IP C++
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
IYG + +P PD+ + P R+ +P A+ FS G RNCIG+++A+ ++++
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVV 489
Query: 209 AHLVRRYKVTAD-ISKIEFKMDVIMTPSDNCYVDFE 243
A + R++++ D K+ K ++I+ + ++ E
Sbjct: 490 ALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 97.1 bits (231), Expect = 5e-20
Identities = 64/216 (29%), Positives = 110/216 (50%), Gaps = 23/216 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVASV------C-------- 90
LL +D DG L+DE+IR E DT + G DT+S +A C
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 91 -GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
G +++E +L +T +KE+LR YP + LV R+ +IKL + IP C++
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
IYG + +P PD+ + P R+ +P A+ FS G RNCIG+++A+ ++++
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVV 489
Query: 209 AHLVRRYKVTAD-ISKIEFKMDVIMTPSDNCYVDFE 243
A + R++++ D K+ K ++I+ + ++ E
Sbjct: 490 ALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 97.1 bits (231), Expect = 5e-20
Identities = 64/216 (29%), Positives = 110/216 (50%), Gaps = 23/216 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVASV------C-------- 90
LL +D DG L+DE+IR E DT + G DT+S +A C
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 91 -GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
G +++E +L +T +KE+LR YP + LV R+ +IKL + IP C++
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
IYG + +P PD+ + P R+ +P A+ FS G RNCIG+++A+ ++++
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVV 489
Query: 209 AHLVRRYKVTAD-ISKIEFKMDVIMTPSDNCYVDFE 243
A + R++++ D K+ K ++I+ + ++ E
Sbjct: 490 ALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 97.1 bits (231), Expect = 5e-20
Identities = 64/216 (29%), Positives = 110/216 (50%), Gaps = 23/216 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVASV------C-------- 90
LL +D DG L+DE+IR E DT + G DT+S +A C
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 91 -GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
G +++E +L +T +KE+LR YP + LV R+ +IKL + IP C++
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
IYG + +P PD+ + P R+ +P A+ FS G RNCIG+++A+ ++++
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVV 489
Query: 209 AHLVRRYKVTAD-ISKIEFKMDVIMTPSDNCYVDFE 243
A + R++++ D K+ K ++I+ + ++ E
Sbjct: 490 ALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 95.5 bits (227), Expect = 2e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 95.5 bits (227), Expect = 2e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 64/238 (26%), Positives = 114/238 (47%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSSQLT-- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT++ +
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LR++P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 94.7 bits (225), Expect = 3e-19
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+T+A+ K++LA + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 340 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 400 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 459
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 460 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 501
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 340 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 400 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 459
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 460 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 501
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 340 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 400 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 459
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 460 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 501
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 340 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 400 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 459
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 460 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 501
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 279 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 338
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 339 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 399 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 458
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 459 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 500
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 340 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 400 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 459
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 460 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 501
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 93.9 bits (223), Expect = 5e-19
Identities = 62/222 (27%), Positives = 109/222 (49%), Gaps = 23/222 (10%)
Query: 42 ERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDT-SSQLTVASVC-------- 90
+RK++ L+++L KD G + +D ++ EV T +LAG DT ++ ++ C
Sbjct: 215 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 274
Query: 91 --------GVSDD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YT 139
G+ D + + YT +KET RL P +P + R + + T
Sbjct: 275 ERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCT 334
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA VL I+GL+ +P + F P R+ + +P A+ FS G RNCIG+ +
Sbjct: 335 LPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEF 394
Query: 200 ALISTKIILAHLVRRYKVTADISK-IEFKMDVIMTPSDNCYV 240
A+I K+ +A ++ ++VT D ++ + F I+ P + Y+
Sbjct: 395 AMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYL 436
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 483 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 483 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 483 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 237 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 296
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 297 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 356
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 357 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 416
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 417 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 451
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 483 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 92.3 bits (219), Expect = 1e-18
Identities = 63/215 (29%), Positives = 103/215 (47%), Gaps = 22/215 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVA------SVCGVSDDDVE 98
LL KD DG AL+DE+IR E DT + G DT++ +A C ++
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 99 KHHHPR---------LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
K P+ L + +KE+LRL+P P + R +I L + IP C++
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
I G++ +P PD + P R+ +P AF FS G RNCIG+ +A+ K++L
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVL 482
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
A ++ ++ D ++ K+++IM ++ E
Sbjct: 483 ALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 89.4 bits (212), Expect = 1e-17
Identities = 66/238 (27%), Positives = 112/238 (47%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P V
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++L + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 89.4 bits (212), Expect = 1e-17
Identities = 66/238 (27%), Positives = 112/238 (47%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P V
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++L + R++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGIWLRVE 517
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 87.0 bits (206), Expect = 5e-17
Identities = 65/238 (27%), Positives = 111/238 (46%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P V
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++L + ++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 87.0 bits (206), Expect = 5e-17
Identities = 63/238 (26%), Positives = 111/238 (46%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSSQ---- 83
S + D L ++ K +++LL +D +G L+DE+IR E DT + G DT++
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 84 --LTVA------SVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
+A C ++ K P+ L + LKE+LRL+P IP
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFA 399
Query: 127 RKPENEIKLKNY-TIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R ++ L + IP + C + I+ ++ +P PD + P R+ +P AF
Sbjct: 400 RGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++LA + R+++ D + ++++ D ++ E
Sbjct: 460 PFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVE 517
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 87.0 bits (206), Expect = 5e-17
Identities = 65/238 (27%), Positives = 111/238 (46%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P V
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++L + ++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 87.0 bits (206), Expect = 5e-17
Identities = 65/238 (27%), Positives = 111/238 (46%), Gaps = 24/238 (10%)
Query: 30 SNWLGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT- 85
S + D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 86 ----------VASVCGVSDDDVEKHHHPR---------LVYTEAVLKETLRLYPTIPLVL 126
C ++ K P+ L + +KE+LRL+P +P V
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 127 RKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFA 185
R +I L + IP C++ ++G + +P PD + P R+ +P AF
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFI 459
Query: 186 GFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
FS G RNCIG+ +A+ K++L + ++V D ++ K ++++ ++ E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 86.6 bits (205), Expect = 7e-17
Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 22/207 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVAS-----------VCGVS 93
LL K +G L+D+++R EVDT + G DT++ +A+ + G+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLL 355
Query: 94 DD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGI 150
D + +H ++ YT +KE LRLYP +P + R+ + + ++P +L I
Sbjct: 356 GDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSI 415
Query: 151 YGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAH 210
YGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 416 YGLHHNPKVWPNPEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 211 LVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I M ++ S N
Sbjct: 474 TLLRFELLPDPTRIPIPMARLVLKSKN 500
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 86.6 bits (205), Expect = 7e-17
Identities = 62/207 (29%), Positives = 104/207 (50%), Gaps = 22/207 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVAS-----------VCGVS 93
LL K +G L+D+++R EVDT + G DT++ +A+ + G+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLL 355
Query: 94 DD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGI 150
D + +H ++ YT +KE LRLYP +P + R+ + + ++P +L I
Sbjct: 356 GDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSI 415
Query: 151 YGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAH 210
YGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 416 YGLHHNPKVWPNLEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 211 LVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I M ++ S N
Sbjct: 474 TLLRFELLPDPTRIPIPMARLVLKSKN 500
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 86.6 bits (205), Expect = 7e-17
Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 3/141 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L +AV+KE LRLYP +P R P+ +I + +Y IP N+ L Y +R P P+
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEP 425
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD--I 221
++FRP RWL G P +P A F GKR+C+G+ A + ++ LA ++ ++V +
Sbjct: 426 NSFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGA 484
Query: 222 SKIEFKMDVIMTPSDNCYVDF 242
+ + K ++ P + + F
Sbjct: 485 APVRPKTRTVLVPERSINLQF 505
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 85.4 bits (202), Expect = 2e-16
Identities = 63/235 (26%), Positives = 111/235 (47%), Gaps = 24/235 (10%)
Query: 33 LGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT---- 85
+ D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 283 IDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLY 342
Query: 86 -------VASVCGVSDDDVEKHHHP---------RLVYTEAVLKETLRLYPTIPLVLRKP 129
C ++ K P +L + +KE+LRL+P +P++ R
Sbjct: 343 HLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCC 402
Query: 130 ENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFS 188
+ L + IP C++ I G++ +P PD + P R+ + +P AF FS
Sbjct: 403 TQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFS 462
Query: 189 VGKRNCIGKTYALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDNCYVDFE 243
G RNCIG+ +A+ K++LA + +++ ++ K ++I+ ++ E
Sbjct: 463 AGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVE 517
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 340
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 341 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 400 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 459
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 460 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 497
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 325
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 326 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 384
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 385 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 444
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 445 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 482
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 340
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 341 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 400 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 459
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 460 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 497
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 325
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 326 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 384
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 385 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 444
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 445 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 482
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 340
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 341 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 400 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 459
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 460 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 497
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 340
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 341 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 399
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 400 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 459
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 460 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 497
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQH 325
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 326 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 384
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 385 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 444
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 445 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 482
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/218 (27%), Positives = 102/218 (46%), Gaps = 24/218 (11%)
Query: 43 RKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTSS------------------ 82
R+ L++LL +D D L+D ++R EVDT + G DT++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQH 339
Query: 83 --QLTVASVCGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIK-LKNYT 139
+ V + G D + ++ Y +KE+ RLYP +P V R+ + + +
Sbjct: 340 RCREEVREILG-DQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRS 398
Query: 140 IPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTY 199
+PA S + IY L+R+ PD F R+ +P AF FS G RNCIG+ +
Sbjct: 399 LPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQF 458
Query: 200 ALISTKIILAHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A+ K++ A + R++ + D S++ KM ++ S N
Sbjct: 459 AMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKN 496
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 85.0 bits (201), Expect = 2e-16
Identities = 61/207 (29%), Positives = 104/207 (50%), Gaps = 22/207 (10%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVAS-----------VCGVS 93
LL K +G L+D+++R EVDT + G DT++ +A+ + G+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLL 355
Query: 94 DD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGI 150
D + +H ++ YT +KE LRLYP +P + R+ + + ++P +L I
Sbjct: 356 GDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSI 415
Query: 151 YGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAH 210
YGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 416 YGLHHNPKVWPNLEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNQLKVARAL 473
Query: 211 LVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 474 TLLRFELLPDPTRIPIPIARLVLKSKN 500
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 84.2 bits (199), Expect = 4e-16
Identities = 60/209 (28%), Positives = 101/209 (48%), Gaps = 24/209 (11%)
Query: 33 LGDGLITSSERKFKSMLELLL--KDSDGDALTDEEIRDEVDTLILAGSDTS-SQLT---- 85
+ D L ++ K +++LL KD DG L+DE+IR E DT + G DT+ S L+
Sbjct: 283 IDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLY 342
Query: 86 -------VASVCGVSDDDVEKHHHP---------RLVYTEAVLKETLRLYPTIPLVLRKP 129
C ++ K P +L + +KE+LRL+P +P++ R
Sbjct: 343 HLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCC 402
Query: 130 ENEIKLKN-YTIPANSNCVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFS 188
+ L + IP C++ I G++ +P PD + P R+ + +P AF FS
Sbjct: 403 TQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFS 462
Query: 189 VGKRNCIGKTYALISTKIILAHLVRRYKV 217
G RNCIG+ +A+ K++LA + +++
Sbjct: 463 AGPRNCIGQAFAMAEMKVVLALTLLHFRI 491
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 83.4 bits (197), Expect = 7e-16
Identities = 60/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 82.2 bits (194), Expect = 2e-15
Identities = 60/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 82.2 bits (194), Expect = 2e-15
Identities = 60/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 82.2 bits (194), Expect = 2e-15
Identities = 60/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 82.2 bits (194), Expect = 2e-15
Identities = 60/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 81.8 bits (193), Expect = 2e-15
Identities = 58/195 (29%), Positives = 97/195 (49%), Gaps = 24/195 (12%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKI 224
+ R+++ D ++I
Sbjct: 473 LTLLRFELLPDPTRI 487
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 81.4 bits (192), Expect = 3e-15
Identities = 60/208 (28%), Positives = 101/208 (48%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNQLKVARA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++ M ++ S N
Sbjct: 473 LTLLRFELLPDPTRTPIPMARLVLKSKN 500
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 80.6 bits (190), Expect = 5e-15
Identities = 59/208 (28%), Positives = 102/208 (49%), Gaps = 24/208 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRL+P +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+ A
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVATA 472
Query: 210 HLVRRYKVTADISKIEFKMDVIMTPSDN 237
+ R+++ D ++I + ++ S N
Sbjct: 473 LTLLRFELLPDPTRIPIPIARLVLKSKN 500
>AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 421
Score = 79.8 bits (188), Expect = 8e-15
Identities = 47/149 (31%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Query: 90 CGVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVL 148
C S + ++H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 256 CWCSGWNCFRNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLL 315
Query: 149 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIIL 208
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+
Sbjct: 316 SIYGLHHNPKVWPNLEVFDPSRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNQLKVAR 373
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A + R+++ D ++I M ++ S N
Sbjct: 374 ALTLLRFELLPDPTRIPIPMARLVLKSKN 402
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 78.2 bits (184), Expect = 2e-14
Identities = 57/211 (27%), Positives = 100/211 (47%), Gaps = 25/211 (11%)
Query: 61 LTDEEIRDEVDTLILAGSDTSSQLTVASVCGVSDD-DVEKHHHPRLV------------- 106
L+ E + L++AG DT+S ++ +S D +++K H +V
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKD 379
Query: 107 -----YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGP 161
+AVLKETLRLYP +P R E EI++ + P N+ V Y ++R P
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFS 439
Query: 162 DAHTFRPERWLEPG--GVPGNPNAFAG--FSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
+ +F+P RWL P + F F G R C+G+ A + +++LA L+++YKV
Sbjct: 440 EPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
Query: 218 --TADISKIEFKMDVIMTPSDNCYVDFELRK 246
+ +++ +++ P+ + F R+
Sbjct: 500 VLAPETGELKSVARIVLVPNKKVGLQFLQRQ 530
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 77.4 bits (182), Expect = 4e-14
Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+AVLKETLRLYP +P R E EI++ + P N+ V Y ++R P + +F+P
Sbjct: 386 KAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQP 445
Query: 169 ERWLEPG--GVPGNPNAFAG--FSVGKRNCIGKTYALISTKIILAHLVRRYKV--TADIS 222
RWL P + F F G R C+G+ A + +++LA L+++YKV +
Sbjct: 446 HRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETG 505
Query: 223 KIEFKMDVIMTPSDNCYVDFELRK 246
+++ +++ P+ + F R+
Sbjct: 506 ELKSVARIVLVPNKKVGLQFLQRQ 529
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 77.4 bits (182), Expect = 4e-14
Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+AVLKETLRLYP +P R E EI++ + P N+ V Y ++R P + +F+P
Sbjct: 387 KAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQP 446
Query: 169 ERWLEPG--GVPGNPNAFAG--FSVGKRNCIGKTYALISTKIILAHLVRRYKV--TADIS 222
RWL P + F F G R C+G+ A + +++LA L+++YKV +
Sbjct: 447 HRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETG 506
Query: 223 KIEFKMDVIMTPSDNCYVDFELRK 246
+++ +++ P+ + F R+
Sbjct: 507 ELKSVARIVLVPNKKVGLQFLQRQ 530
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 77.4 bits (182), Expect = 4e-14
Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+AVLKETLRLYP +P R E EI++ + P N+ V Y ++R P + +F+P
Sbjct: 387 KAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQP 446
Query: 169 ERWLEPG--GVPGNPNAFAG--FSVGKRNCIGKTYALISTKIILAHLVRRYKV--TADIS 222
RWL P + F F G R C+G+ A + +++LA L+++YKV +
Sbjct: 447 HRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETG 506
Query: 223 KIEFKMDVIMTPSDNCYVDFELRK 246
+++ +++ P+ + F R+
Sbjct: 507 ELKSVARIVLVPNKKVGLQFLQRQ 530
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 77.4 bits (182), Expect = 4e-14
Identities = 44/144 (30%), Positives = 75/144 (52%), Gaps = 6/144 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+AVLKETLRLYP +P R E EI++ + P N+ V Y ++R P + +F+P
Sbjct: 387 KAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQP 446
Query: 169 ERWLEPG--GVPGNPNAFAG--FSVGKRNCIGKTYALISTKIILAHLVRRYKV--TADIS 222
RWL P + F F G R C+G+ A + +++LA L+++YKV +
Sbjct: 447 HRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETG 506
Query: 223 KIEFKMDVIMTPSDNCYVDFELRK 246
+++ +++ P+ + F R+
Sbjct: 507 ELKSVARIVLVPNKKVGLQFLQRQ 530
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 76.2 bits (179), Expect = 1e-13
Identities = 60/209 (28%), Positives = 102/209 (48%), Gaps = 25/209 (11%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 297 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 356
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 357 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 415
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKI-IL 208
IYGL+ +P P+ F P R+ PG + +AF FS G RNCIGK +A+ K+
Sbjct: 416 IYGLHHNPKVWPNPEVFDPFRFA-PGSAQ-HSHAFLPFSGGSRNCIGKQFAMNELKVGQQ 473
Query: 209 AHLVRRYKVTADISKIEFKMDVIMTPSDN 237
A + R+++ D ++I + ++ S N
Sbjct: 474 ALTLVRFELLPDPTRIPIPIARLVLKSKN 502
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 73.7 bits (173), Expect = 5e-13
Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 3/147 (2%)
Query: 103 PRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
P++ A+LKETLRL+P +P R + ++ + Y IP + L Y + P
Sbjct: 226 PKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPR 285
Query: 163 AHTFRPERWLEPGGVPGNPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY--KVTA 219
A FRPERWL G + N F G R+CIG+ A + +++ L++ + K ++
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 220 DISKIEFKMDVIMTPSDNCYVDFELRK 246
+ + K ++TP +V F RK
Sbjct: 346 QTNAVHAKTHGLLTPGGPIHVRFVNRK 372
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 73.7 bits (173), Expect = 5e-13
Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 3/147 (2%)
Query: 103 PRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
P++ A+LKETLRL+P +P R + ++ + Y IP + L Y + P
Sbjct: 226 PKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPR 285
Query: 163 AHTFRPERWLEPGGVPGNPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY--KVTA 219
A FRPERWL G + N F G R+CIG+ A + +++ L++ + K ++
Sbjct: 286 AKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSS 345
Query: 220 DISKIEFKMDVIMTPSDNCYVDFELRK 246
+ + K ++TP +V F RK
Sbjct: 346 QTNAVHAKTHGLLTPGGPIHVRFVNRK 372
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 72.9 bits (171), Expect = 9e-13
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 PALFPRPERYNPQRWLDIRG-SGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472
Query: 217 V-TADISKIEFKMDVIMTPS 235
V T I+ I+ PS
Sbjct: 473 VETLTQEDIKMVYSFILRPS 492
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 72.9 bits (171), Expect = 9e-13
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 PALFPRPERYNPQRWLDIRG-SGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472
Query: 217 V-TADISKIEFKMDVIMTPS 235
V T I+ I+ PS
Sbjct: 473 VETLTQEDIKMVYSFILRPS 492
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 72.9 bits (171), Expect = 9e-13
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 425 HPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRN 484
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 485 PALFPRPERYNPQRWLDIRG-SGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 543
Query: 217 V-TADISKIEFKMDVIMTPS 235
V T I+ I+ PS
Sbjct: 544 VETLTQEDIKMVYSFILRPS 563
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 72.9 bits (171), Expect = 9e-13
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 PALFPRPERYNPQRWLDIRG-SGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472
Query: 217 V-TADISKIEFKMDVIMTPS 235
V T I+ I+ PS
Sbjct: 473 VETLTQEDIKMVYSFILRPS 492
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 72.5 bits (170), Expect = 1e-12
Identities = 46/140 (32%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 PALFPRPERYNPQRWLDIRG-SGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472
Query: 217 V-TADISKIEFKMDVIMTPS 235
V T I+ I+ PS
Sbjct: 473 VETLTQEDIKMVYSFILRPS 492
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 72.5 bits (170), Expect = 1e-12
Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTF 166
Y +A LKE++RL P++P R + L Y +P + +L L D+ F
Sbjct: 234 YLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQF 293
Query: 167 RPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA-DISKIE 225
RPERWL+ NP A F VGKR CIG+ A + + L +VR+Y + A D +E
Sbjct: 294 RPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 352
Query: 226 FKMDVIMTPSDNCYVDF 242
+ PS + F
Sbjct: 353 MLHSGTLVPSRELPIAF 369
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 72.5 bits (170), Expect = 1e-12
Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTF 166
Y +A LKE++RL P++P R + L Y +P + +L L D+ F
Sbjct: 376 YLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQF 435
Query: 167 RPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA-DISKIE 225
RPERWL+ NP A F VGKR CIG+ A + + L +VR+Y + A D +E
Sbjct: 436 RPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 494
Query: 226 FKMDVIMTPSDNCYVDF 242
+ PS + F
Sbjct: 495 MLHSGTLVPSRELPIAF 511
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 72.5 bits (170), Expect = 1e-12
Identities = 45/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTF 166
Y +A LKE++RL P++P R + L Y +P + +L L D+ F
Sbjct: 234 YLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQF 293
Query: 167 RPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA-DISKIE 225
RPERWL+ NP A F VGKR CIG+ A + + L +VR+Y + A D +E
Sbjct: 294 RPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 352
Query: 226 FKMDVIMTPSDNCYVDF 242
+ PS + F
Sbjct: 353 MLHSGTLVPSRELPIAF 369
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 72.1 bits (169), Expect = 2e-12
Identities = 44/130 (33%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTF 166
Y +A LKE++RL P++P R + L Y +P + +L L D+ F
Sbjct: 119 YLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQF 178
Query: 167 RPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA-DISKIE 225
RPERWL+ NP A F VGKR CIG+ A + + L +VR+Y + A D +E
Sbjct: 179 RPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 237
Query: 226 FKMDVIMTPS 235
+ PS
Sbjct: 238 MLHSGTLVPS 247
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 72.1 bits (169), Expect = 2e-12
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Query: 101 HHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVW 159
H ++ YT +KE LRLY + + R + I + ++PA + I+ L+ +P +
Sbjct: 358 HLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYF 417
Query: 160 GPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
D F P R+ +P AF FS G RNCIG+ +A+I K+ +A + R+K+
Sbjct: 418 WEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAP 477
Query: 220 DISK 223
D S+
Sbjct: 478 DHSR 481
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 72.1 bits (169), Expect = 2e-12
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Query: 101 HHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVW 159
H ++ YT +KE LRLY + + R + I + ++PA + I+ L+ +P +
Sbjct: 358 HLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYF 417
Query: 160 GPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
D F P R+ +P AF FS G RNCIG+ +A+I K+ +A + R+K+
Sbjct: 418 WEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAP 477
Query: 220 DISK 223
D S+
Sbjct: 478 DHSR 481
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 72.1 bits (169), Expect = 2e-12
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Query: 101 HHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVW 159
H ++ YT +KE LRLY + + R + I + ++PA + I+ L+ +P +
Sbjct: 358 HLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYF 417
Query: 160 GPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
D F P R+ +P AF FS G RNCIG+ +A+I K+ +A + R+K+
Sbjct: 418 WEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAP 477
Query: 220 DISK 223
D S+
Sbjct: 478 DHSR 481
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 72.1 bits (169), Expect = 2e-12
Identities = 39/124 (31%), Positives = 64/124 (51%), Gaps = 1/124 (0%)
Query: 101 HHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGIYGLNRHPVW 159
H ++ YT +KE LRLY + + R + I + ++PA + I+ L+ +P +
Sbjct: 358 HLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYF 417
Query: 160 GPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
D F P R+ +P AF FS G RNCIG+ +A+I K+ +A + R+K+
Sbjct: 418 WEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAP 477
Query: 220 DISK 223
D S+
Sbjct: 478 DHSR 481
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/147 (31%), Positives = 71/147 (48%), Gaps = 7/147 (4%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P + P+RWL+ G G F G R C+G+ A ++L H+++R+
Sbjct: 414 AALFPRPERYNPQRWLDIRG-SGRNLHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRFL 472
Query: 217 V-TADISKIEFKMDVIMTPSDNCYVDF 242
V T I+ I+ P + + F
Sbjct: 473 VETLTQEDIKMVYSFILRPGTSPLLTF 499
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 71.3 bits (167), Expect = 3e-12
Identities = 45/137 (32%), Positives = 64/137 (46%), Gaps = 2/137 (1%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTF 166
Y +A LKE++RL P +P R + L Y +P + +L L D+ F
Sbjct: 375 YLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQF 434
Query: 167 RPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA-DISKIE 225
RPERWL+ NP A F VGKR CIG+ A + + L +VR+Y + A D +E
Sbjct: 435 RPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVE 493
Query: 226 FKMDVIMTPSDNCYVDF 242
+ PS + F
Sbjct: 494 MLHSGTLVPSRELPIAF 510
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 69.7 bits (163), Expect = 9e-12
Identities = 56/201 (27%), Positives = 87/201 (43%), Gaps = 24/201 (11%)
Query: 39 TSSERKFKSMLELLLKDS--DGDALTDEEIRDEVDTLILAGSDTSSQL------------ 84
T S+ K +L+ LL + DG LTD+E+ + L+LAG TSS
Sbjct: 272 TQSQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDK 331
Query: 85 TVASVCGVSDDDVEKHHHPRLVYTEA--------VLKETLRLYPTIPLVLRKPENEIKLK 136
T+ C + V + P L Y + ++ETLRL P I +++R +
Sbjct: 332 TLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTVA 391
Query: 137 NYTIPANSN-CVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCI 195
YTIP CV W + F P+R+L+ G A+ F G+ CI
Sbjct: 392 GYTIPPGHQVCVSPTVNQRLKDSW-VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 450
Query: 196 GKTYALISTKIILAHLVRRYK 216
G+ +A + K I + ++R Y+
Sbjct: 451 GENFAYVQIKTIWSTMLRLYE 471
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 7/147 (4%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 AALFPRPERYNPQRWLDIRG-SGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFL 472
Query: 217 V-TADISKIEFKMDVIMTPSDNCYVDF 242
V T I+ I+ P + + F
Sbjct: 473 VETLTQEDIKMVYSFILRPGTSPLLTF 499
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/147 (30%), Positives = 70/147 (47%), Gaps = 7/147 (4%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP + R +++ L+NY IPA + + +Y L R+
Sbjct: 354 HPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRN 413
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P + P+RWL+ G G F G R C+G+ A ++L H+++ +
Sbjct: 414 AALFPRPERYNPQRWLDIRG-SGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFL 472
Query: 217 V-TADISKIEFKMDVIMTPSDNCYVDF 242
V T I+ I+ P + + F
Sbjct: 473 VETLTQEDIKMVYSFILRPGTSPLLTF 499
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 69.3 bits (162), Expect = 1e-11
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 2/111 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
RL Y VLKE+LRLYP R E E + +P N+ + Y + R + D
Sbjct: 349 RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDP 408
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRR 214
TF P+R+ G P + FS+G R+CIG+ +A + K+++A L++R
Sbjct: 409 LTFNPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 69.3 bits (162), Expect = 1e-11
Identities = 38/111 (34%), Positives = 58/111 (52%), Gaps = 2/111 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
RL Y VLKE+LRLYP R E E + +P N+ + Y + R + D
Sbjct: 349 RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDP 408
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRR 214
TF P+R+ G P + FS+G R+CIG+ +A + K+++A L++R
Sbjct: 409 LTFNPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 68.9 bits (161), Expect = 2e-11
Identities = 56/199 (28%), Positives = 86/199 (43%), Gaps = 24/199 (12%)
Query: 41 SERKFKSMLELLLKDS--DGDALTDEEIRDEVDTLILAGSDTSSQL------------TV 86
S+ K +L+ LL + DG LTD+E+ + L+LAG TSS T+
Sbjct: 280 SQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTL 339
Query: 87 ASVCGVSDDDVEKHHHPRLVYTEA--------VLKETLRLYPTIPLVLRKPENEIKLKNY 138
C + V + P L Y + +KETLRL P I +++R + Y
Sbjct: 340 QKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 399
Query: 139 TIPANSN-CVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGK 197
TIP CV W + F P+R+L+ G A+ F G+ CIG+
Sbjct: 400 TIPPGHQVCVSPTVNQRLKDSW-VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458
Query: 198 TYALISTKIILAHLVRRYK 216
+A + K I + ++R Y+
Sbjct: 459 NFAYVQIKTIWSTMLRLYE 477
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 68.9 bits (161), Expect = 2e-11
Identities = 56/199 (28%), Positives = 86/199 (43%), Gaps = 24/199 (12%)
Query: 41 SERKFKSMLELLLKDS--DGDALTDEEIRDEVDTLILAGSDTSSQL------------TV 86
S+ K +L+ LL + DG LTD+E+ + L+LAG TSS T+
Sbjct: 280 SQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTL 339
Query: 87 ASVCGVSDDDVEKHHHPRLVYTEA--------VLKETLRLYPTIPLVLRKPENEIKLKNY 138
C + V + P L Y + +KETLRL P I +++R + Y
Sbjct: 340 QKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 399
Query: 139 TIPANSN-CVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGK 197
TIP CV W + F P+R+L+ G A+ F G+ CIG+
Sbjct: 400 TIPPGHQVCVSPTVNQRLKDSW-VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458
Query: 198 TYALISTKIILAHLVRRYK 216
+A + K I + ++R Y+
Sbjct: 459 NFAYVQIKTIWSTMLRLYE 477
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 68.9 bits (161), Expect = 2e-11
Identities = 56/199 (28%), Positives = 86/199 (43%), Gaps = 24/199 (12%)
Query: 41 SERKFKSMLELLLKDS--DGDALTDEEIRDEVDTLILAGSDTSSQL------------TV 86
S+ K +L+ LL + DG LTD+E+ + L+LAG TSS T+
Sbjct: 280 SQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTL 339
Query: 87 ASVCGVSDDDVEKHHHPRLVYTEA--------VLKETLRLYPTIPLVLRKPENEIKLKNY 138
C + V + P L Y + +KETLRL P I +++R + Y
Sbjct: 340 QKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGY 399
Query: 139 TIPANSN-CVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGK 197
TIP CV W + F P+R+L+ G A+ F G+ CIG+
Sbjct: 400 TIPPGHQVCVSPTVNQRLKDSW-VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458
Query: 198 TYALISTKIILAHLVRRYK 216
+A + K I + ++R Y+
Sbjct: 459 NFAYVQIKTIWSTMLRLYE 477
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 68.5 bits (160), Expect = 2e-11
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 102 HPRLVYTE-----AVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRH 156
HP+ TE A LKETLRLYP ++ R +++ L+NY IPA + + +Y L R+
Sbjct: 144 HPQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYSLGRN 203
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAH 210
P P + P+RWL+ G G F G R C+G+ A ++L H
Sbjct: 204 PALFPRPERYNPQRWLDIKG-SGRNFYHVPFGFGMRQCLGRRLAEADMLLLLQH 256
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 68.5 bits (160), Expect = 2e-11
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 24/199 (12%)
Query: 41 SERKFKSMLELLLKDS--DGDALTDEEIRDEVDTLILAGSDTSSQL------------TV 86
S+ K +L+ LL + DG LTD+E+ + L+LAG TSS T+
Sbjct: 280 SQEKIDDILQTLLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTL 339
Query: 87 ASVCGVSDDDVEKHHHPRLVYTEA--------VLKETLRLYPTIPLVLRKPENEIKLKNY 138
C + V + P L Y + +KETLRL P + +++R + Y
Sbjct: 340 QKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVAGY 399
Query: 139 TIPANSN-CVLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGK 197
TIP CV W + F P+R+L+ G A+ F G+ CIG+
Sbjct: 400 TIPPGHQVCVSPTVNQRLKDSW-VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGE 458
Query: 198 TYALISTKIILAHLVRRYK 216
+A + K I + ++R Y+
Sbjct: 459 NFAYVQIKTIWSTMLRLYE 477
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ YTEAVL E LR +PL + + ++ Y+IP + + +Y ++ + D
Sbjct: 357 KMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRD 416
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L+ G A FS+G+R+C+G+ A + + L++R+
Sbjct: 417 PEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ YTEAVL E LR +PL + + ++ Y+IP + + +Y ++ + D
Sbjct: 357 KMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRD 416
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L+ G A FS+G+R+C+G+ A + + L++R+
Sbjct: 417 PEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ YTEAVL E LR +PL + + ++ Y+IP + + +Y ++ + D
Sbjct: 357 KMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRD 416
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L+ G A FS+G+R+C+G+ A + + L++R+
Sbjct: 417 PEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRF 469
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 66.5 bits (155), Expect = 8e-11
Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+A +KETLRL+P + R N++ L++Y IPA + + IY L R P + D F P
Sbjct: 378 KASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDP 437
Query: 169 ERWLEPGGVPGNPNAF--AGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD-ISKIE 225
RWL N F GF G R C+G+ A + I L +++ ++V +S +
Sbjct: 438 TRWLSK---DKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVG 494
Query: 226 FKMDVIMTP 234
++I+ P
Sbjct: 495 TTFNLILMP 503
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 66.5 bits (155), Expect = 8e-11
Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+A +KETLRL+P + R N++ L++Y IPA + + IY L R P + D F P
Sbjct: 96 KASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDP 155
Query: 169 ERWLEPGGVPGNPNAF--AGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD-ISKIE 225
RWL N F GF G R C+G+ A + I L +++ ++V +S +
Sbjct: 156 TRWLSK---DKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVG 212
Query: 226 FKMDVIMTP 234
++I+ P
Sbjct: 213 TTFNLILMP 221
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 66.5 bits (155), Expect = 8e-11
Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+A +KETLRL+P + R N++ L++Y IPA + + IY L R P + D F P
Sbjct: 378 KASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDP 437
Query: 169 ERWLEPGGVPGNPNAF--AGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD-ISKIE 225
RWL N F GF G R C+G+ A + I L +++ ++V +S +
Sbjct: 438 TRWLSK---DKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVG 494
Query: 226 FKMDVIMTP 234
++I+ P
Sbjct: 495 TTFNLILMP 503
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP S V+ Y L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 412 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 470
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 471 QIPLKLD 477
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP S V+ Y L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 412 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 470
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 471 QIPLKLD 477
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 66.5 bits (155), Expect = 8e-11
Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 6/129 (4%)
Query: 109 EAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHTFRP 168
+A +KETLRL+P + R N++ L++Y IPA + + IY L R P + D F P
Sbjct: 378 KASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDP 437
Query: 169 ERWLEPGGVPGNPNAF--AGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTAD-ISKIE 225
RWL N F GF G R C+G+ A + I L +++ ++V +S +
Sbjct: 438 TRWLSK---DKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVG 494
Query: 226 FKMDVIMTP 234
++I+ P
Sbjct: 495 TTFNLILMP 503
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP S V+ Y L+ P + +
Sbjct: 23 QMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 82
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 83 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 141
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 142 QIPLKLD 148
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP S V+ Y L+ P + +
Sbjct: 10 QMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 69
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 70 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 128
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 129 QIPLKLD 135
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 66.5 bits (155), Expect = 8e-11
Identities = 36/127 (28%), Positives = 66/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP S V+ Y L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 412 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 470
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 471 QIPLKLD 477
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 323 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 382
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 383 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 437
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 65.3 bits (152), Expect = 2e-10
Identities = 36/127 (28%), Positives = 65/127 (51%), Gaps = 2/127 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R ++++ IP S V+ Y L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
FRPER+ + +P + F G RNCIG +AL++ K+ L +++ + +
Sbjct: 412 EEFRPERFSKKKD-SIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKET 470
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 471 QIPLKLD 477
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 65.3 bits (152), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 64.9 bits (151), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 390 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 449
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 450 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQA 504
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 64.9 bits (151), Expect = 2e-10
Identities = 32/115 (27%), Positives = 54/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPK 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
TF PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 TFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 63.3 bits (147), Expect = 8e-10
Identities = 31/115 (26%), Positives = 53/115 (46%)
Query: 105 LVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAH 164
L Y + V+ ETLR+YP R+ + ++ IPA + + + L+ P P
Sbjct: 391 LPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPE 450
Query: 165 TFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTA 219
F PER+ P + F G R+C+G L+ K+ L H++ +++ A
Sbjct: 451 NFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQA 505
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 351 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP 410
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 411 EKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 462
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 202 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 261
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 262 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 313
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 279 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 338
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 339 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 390
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 62.9 bits (146), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 352 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 353 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP 412
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 413 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 464
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 62.5 bits (145), Expect = 1e-09
Identities = 31/112 (27%), Positives = 59/112 (52%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + R + ++++ IP ++ Y L+R P + +
Sbjct: 353 QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEP 412
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 413 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 464
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/112 (27%), Positives = 58/112 (51%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L Y + V+ ETLRL+P + R + ++++ IP ++ Y L+ P + +
Sbjct: 352 QLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 242 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 301
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 302 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 361
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 362 QIPLKLD 368
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/112 (27%), Positives = 58/112 (51%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L Y + V+ ETLRL+P + R + ++++ IP ++ Y L+ P + +
Sbjct: 352 QLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/112 (27%), Positives = 58/112 (51%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L Y + V+ ETLRL+P + R + ++++ IP ++ Y L+ P + +
Sbjct: 352 QLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 31/112 (27%), Positives = 58/112 (51%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
+L Y + V+ ETLRL+P + R + ++++ IP ++ Y L+ P + +
Sbjct: 352 QLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+ + +P + F G RNCIG +AL++ K+ L +++ +
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 62.1 bits (144), Expect = 2e-09
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADIS 222
F PER+ + + + F G RNCIG +AL + K+ + ++ + +
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKET 471
Query: 223 KIEFKMD 229
+I K+D
Sbjct: 472 QIPLKLD 478
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 60.9 bits (141), Expect = 4e-09
Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 22/162 (13%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSSQ------LTVAS-----------VCGVS 93
LL K +G L+D+++R EVDT + G DT++ +A+ + G+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLL 355
Query: 94 DD--DVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGI 150
D + +H ++ YT +KE LRLYP +P + R+ + + ++P +L I
Sbjct: 356 GDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSI 415
Query: 151 YGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKR 192
YGL+ +P P+ F P R+ PG + +AF FS G R
Sbjct: 416 YGLHHNPKVWPNLEVFDPSRF-APGSAQ-HSHAFLPFSGGSR 455
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 60.1 bits (139), Expect = 7e-09
Identities = 33/96 (34%), Positives = 51/96 (53%), Gaps = 3/96 (3%)
Query: 100 HHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLGIYGLNRHPV 158
+H ++ YT +KE LRLYP +P + R+ + + ++P +L IYGL+ +P
Sbjct: 48 NHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGLHHNPK 107
Query: 159 WGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNC 194
P+ F P R+ PG + +AF FS G RNC
Sbjct: 108 VWPNPEVFDPSRF-APGSAQ-HSHAFLPFSGGSRNC 141
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 59.7 bits (138), Expect = 9e-09
Identities = 38/126 (30%), Positives = 56/126 (44%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V H RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDHARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/120 (30%), Positives = 54/120 (45%)
Query: 94 DDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGL 153
D+ ++ +L Y V+KETLRL P +P R +L Y IP N + I
Sbjct: 273 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 332
Query: 154 NRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVR 213
+ + F P+R++ P + +F F G R+C+GK +A I KI L R
Sbjct: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 392
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/120 (30%), Positives = 54/120 (45%)
Query: 94 DDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGL 153
D+ ++ +L Y V+KETLRL P +P R +L Y IP N + I
Sbjct: 342 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 154 NRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVR 213
+ + F P+R++ P + +F F G R+C+GK +A I KI L R
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 461
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 58.4 bits (135), Expect = 2e-08
Identities = 36/120 (30%), Positives = 54/120 (45%)
Query: 94 DDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGL 153
D+ ++ +L Y V+KETLRL P +P R +L Y IP N + I
Sbjct: 342 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 154 NRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVR 213
+ + F P+R++ P + +F F G R+C+GK +A I KI L R
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 461
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 58.0 bits (134), Expect = 3e-08
Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 107 YTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT AV+ E R+ IPL V R+ + L Y +P + + + L+R P T
Sbjct: 361 YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT 420
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISK-- 223
F P+ +LE G AF FS+GKR C+G+ A I L++++ ++
Sbjct: 421 FNPDHFLENGQFKKR-EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKL 479
Query: 224 -IEFKMDVIMTP 234
++F+M + ++P
Sbjct: 480 SLKFRMGITISP 491
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 58.0 bits (134), Expect = 3e-08
Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 107 YTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT AV+ E R+ IPL V R+ + L Y +P + + + L+R P T
Sbjct: 361 YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT 420
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISK-- 223
F P+ +LE G AF FS+GKR C+G+ A I L++++ ++
Sbjct: 421 FNPDHFLENGQFKKR-EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKL 479
Query: 224 -IEFKMDVIMTP 234
++F+M + ++P
Sbjct: 480 SLKFRMGITISP 491
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 58.0 bits (134), Expect = 3e-08
Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 107 YTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT AV+ E R+ IPL V R+ + L Y +P + + + L+R P T
Sbjct: 361 YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT 420
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISK-- 223
F P+ +LE G AF FS+GKR C+G+ A I L++++ ++
Sbjct: 421 FNPDHFLENGQFKKR-EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKL 479
Query: 224 -IEFKMDVIMTP 234
++F+M + ++P
Sbjct: 480 SLKFRMGITISP 491
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 58.0 bits (134), Expect = 3e-08
Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 107 YTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT AV+ E R+ IPL V R+ + L Y +P + + + L+R P T
Sbjct: 361 YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT 420
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISK-- 223
F P+ +LE G AF FS+GKR C+G+ A I L++++ ++
Sbjct: 421 FNPDHFLENGQFKKR-EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKL 479
Query: 224 -IEFKMDVIMTP 234
++F+M + ++P
Sbjct: 480 SLKFRMGITISP 491
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 58.0 bits (134), Expect = 3e-08
Identities = 38/132 (28%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 107 YTEAVLKETLRLYPTIPL-VLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT AV+ E R+ IPL V R+ + L Y +P + + + L+R P T
Sbjct: 361 YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT 420
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADISK-- 223
F P+ +LE G AF FS+GKR C+G+ A I L++++ ++
Sbjct: 421 FNPDHFLENGQFKKR-EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKL 479
Query: 224 -IEFKMDVIMTP 234
++F+M + ++P
Sbjct: 480 SLKFRMGITISP 491
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 57.6 bits (133), Expect = 4e-08
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 24/163 (14%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKR 192
IYGL+ +P P+ F P R+ PG + +AF FS G R
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRF-APGSAQ-HSHAFLPFSGGSR 455
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 57.6 bits (133), Expect = 4e-08
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 24/163 (14%)
Query: 51 LLLKDSDGDALTDEEIRDEVDTLILAGSDTSS--------------------QLTVASVC 90
LL K +G L+D+++R EVDT + G DT++ + + S+
Sbjct: 296 LLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLL 355
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKN-YTIPANSNCVLG 149
G + +H ++ YT +KE LRLYP +P + R+ + + ++P +L
Sbjct: 356 G-DGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLS 414
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKR 192
IYGL+ +P P+ F P R+ PG + +AF FS G R
Sbjct: 415 IYGLHHNPKVWPNPEVFDPFRF-APGSAQ-HSHAFLPFSGGSR 455
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 57.6 bits (133), Expect = 4e-08
Identities = 34/128 (26%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPE-RWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADI 221
F PE R+ + + + F G RNCIG +AL + K+ + ++ +
Sbjct: 412 EKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKE 471
Query: 222 SKIEFKMD 229
++I K+D
Sbjct: 472 TQIPLKLD 479
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 57.6 bits (133), Expect = 4e-08
Identities = 34/128 (26%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
++ Y + V+ ETLRL+P + V R + +I++ IP ++ IY L+ P + +
Sbjct: 352 QMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 164 HTFRPE-RWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV-TADI 221
F PE R+ + + + F G RNCIG +AL + K+ + ++ +
Sbjct: 412 EKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKE 471
Query: 222 SKIEFKMD 229
++I K+D
Sbjct: 472 TQIPLKLD 479
>AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol
7alpha-hydroxylase protein.
Length = 469
Score = 57.2 bits (132), Expect = 5e-08
Identities = 35/125 (28%), Positives = 66/125 (52%), Gaps = 7/125 (5%)
Query: 92 VSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIY 151
VS+DD+EK L+ + + ET+RL ++ RK +++ NY IP+ +L +
Sbjct: 317 VSEDDLEK-----LLLIKWCVLETIRLKAP-GVITRKVVKPVEILNYIIPSGDLLMLSPF 370
Query: 152 GLNRHPVWGPDAHTFRPERWLEPGGVPGN-PNAFAGFSVGKRNCIGKTYALISTKIILAH 210
L+R+P + P+ F+PERW + + + F F GK C + +AL+ ++ +
Sbjct: 371 WLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIIL 430
Query: 211 LVRRY 215
++ +Y
Sbjct: 431 ILYKY 435
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 298 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 357
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 358 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 413
Query: 210 HLVRRY 215
L++ +
Sbjct: 414 RLLQAF 419
>BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGTHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 299 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 358
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 359 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 414
Query: 210 HLVRRY 215
L++ +
Sbjct: 415 RLLQAF 420
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 299 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 358
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 359 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 414
Query: 210 HLVRRY 215
L++ +
Sbjct: 415 RLLQAF 420
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 299 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 358
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 359 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 414
Query: 210 HLVRRY 215
L++ +
Sbjct: 415 RLLQAF 420
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 299 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 358
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 359 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 414
Query: 210 HLVRRY 215
L++ +
Sbjct: 415 RLLQAF 420
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 237 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 296
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 297 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 352
Query: 210 HLVRRY 215
L++ +
Sbjct: 353 RLLQAF 358
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 56.4 bits (130), Expect = 9e-08
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 329 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 388
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 389 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 444
Query: 210 HLVRRY 215
L++ +
Sbjct: 445 RLLQAF 450
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 302 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 361
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 362 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 421
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 343 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 402
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 403 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 462
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENE-IKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ YTEA + E RL +PL + +E L+ YTIP + + ++ ++R P
Sbjct: 399 QMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEK 458
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F P R+L+ G F F +GKR C+G+ A + ++ L++ +
Sbjct: 459 PEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENE-IKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ YTEA + E RL +PL + +E L+ YTIP + + ++ ++R P
Sbjct: 399 QMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEK 458
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F P R+L+ G F F +GKR C+G+ A + ++ L++ +
Sbjct: 459 PEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/115 (26%), Positives = 60/115 (52%), Gaps = 3/115 (2%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
RL+ EA ++E LRL P P+++ N + + + + + ++ ++ L+ +
Sbjct: 349 RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQ 408
Query: 163 AHTFRPERWLEPGGVPG-NPN-AFAGFSVGKRNCIGKTYALISTKIILAHLVRRY 215
F PER+L P G +P+ ++ F G R+CIG+ A +I+A L++R+
Sbjct: 409 PDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 55.6 bits (128), Expect = 2e-07
Identities = 30/120 (25%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L G +AF FS+GKRNC G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 55.2 bits (127), Expect = 2e-07
Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 64 GASSSRVPYKDRARLPLLIATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 123
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 124 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 179
Query: 210 HLVRRY 215
L++ +
Sbjct: 180 RLLQAF 185
>BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family
39, subfamily A, polypeptide 1 protein.
Length = 469
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 7/125 (5%)
Query: 92 VSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIY 151
VS+DD+E L+ + + ET+RL ++ RK +++ NY IP+ +L +
Sbjct: 317 VSEDDLEN-----LLLIKWCVLETIRLKAP-GVITRKVVKPVEILNYIIPSGDLLMLSPF 370
Query: 152 GLNRHPVWGPDAHTFRPERWLEPGGVPGN-PNAFAGFSVGKRNCIGKTYALISTKIILAH 210
L+R+P + P+ F+PERW + + + F F GK C + +AL+ ++ +
Sbjct: 371 WLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIIL 430
Query: 211 LVRRY 215
++ +Y
Sbjct: 431 ILYKY 435
>AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family
39, subfamily A, polypeptide 1 protein.
Length = 469
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 7/125 (5%)
Query: 92 VSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIY 151
VS+DD+E L+ + + ET+RL ++ RK +++ NY IP+ +L +
Sbjct: 317 VSEDDLEN-----LLLIKWCVLETIRLKAP-GVITRKVVKPVEILNYIIPSGDLLMLSPF 370
Query: 152 GLNRHPVWGPDAHTFRPERWLEPGGVPGN-PNAFAGFSVGKRNCIGKTYALISTKIILAH 210
L+R+P + P+ F+PERW + + + F F GK C + +AL+ ++ +
Sbjct: 371 WLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIIL 430
Query: 211 LVRRY 215
++ +Y
Sbjct: 431 ILYKY 435
>AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family
39, subfamily A, polypeptide 1 protein.
Length = 469
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 7/125 (5%)
Query: 92 VSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIY 151
VS+DD+E L+ + + ET+RL ++ RK +++ NY IP+ +L +
Sbjct: 317 VSEDDLEN-----LLLIKWCVLETIRLKAP-GVITRKVVKPVEILNYIIPSGDLLMLSPF 370
Query: 152 GLNRHPVWGPDAHTFRPERWLEPGGVPGN-PNAFAGFSVGKRNCIGKTYALISTKIILAH 210
L+R+P + P+ F+PERW + + + F F GK C + +AL+ ++ +
Sbjct: 371 WLHRNPKYFPEPELFKPERWKKANLEKHSFLDCFMAFGSGKFQCPARWFALLEVQMCIIL 430
Query: 211 LVRRY 215
++ +Y
Sbjct: 431 ILYKY 435
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 55.2 bits (127), Expect = 2e-07
Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ SK++ K D+ +TP N +
Sbjct: 458 LK---SKVDPK-DIDITPIANAF 476
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 54.8 bits (126), Expect = 3e-07
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L +IK +NY IP + + + + P+
Sbjct: 213 YTDAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 272
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 273 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 324
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 54.8 bits (126), Expect = 3e-07
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R IP L ++K +NY IP + + + +
Sbjct: 221 DRSHMP---YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHD 277
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ GG N F FS GKR C+G+ A + + L +++ +
Sbjct: 278 NKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFN 337
Query: 217 V 217
+
Sbjct: 338 L 338
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 347 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 406
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 407 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 74 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 133
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 134 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 185
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 325 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 384
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 385 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 436
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 347 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 406
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 407 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 54.4 bits (125), Expect = 4e-07
Identities = 37/126 (29%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G R C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGARVCLGEPLARLELFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 347 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 406
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 407 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 54.4 bits (125), Expect = 4e-07
Identities = 31/112 (27%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 107 YTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRHPVWGPDAHT 165
YT+AV+ E R IP L ++K +NY IP + + + + P+
Sbjct: 347 YTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEM 406
Query: 166 FRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKV 217
F P +L+ GG N F FS GKR C+G+ A + + L +++ + +
Sbjct: 407 FDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 54.0 bits (124), Expect = 5e-07
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 12/111 (10%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVLRKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPDA 163
RL Y VLKE+LRLYP R E E + ++ Y + R + D
Sbjct: 196 RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGFST----------YVMGRMDTYFEDP 245
Query: 164 HTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRR 214
TF P+R+ G P + FS+G R+CIG+ +A + K+++A L++R
Sbjct: 246 LTFNPDRF--GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 294
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 458 LKSQVD----PKDIDITPIANAF 476
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 53.6 bits (123), Expect = 6e-07
Identities = 36/126 (28%), Positives = 54/126 (42%), Gaps = 5/126 (3%)
Query: 91 GVSDDDVEKHHHPRLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLG 149
G S V RL A + E LRL P +PL L + + Y IP + +
Sbjct: 328 GASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPN 387
Query: 150 IYGLNRHPVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILA 209
+ G + H F P+R+LEPG N A A F G C+G+ A + ++L
Sbjct: 388 LQGAHLDETVWERPHEFWPDRFLEPG---KNSRALA-FGCGAPVCLGEPLARLDLFVVLT 443
Query: 210 HLVRRY 215
L++ +
Sbjct: 444 RLLQAF 449
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 161 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 217
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 218 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 277
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 278 LKSQVD----PKDIDITPIANAF 296
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 282 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 338
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 339 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 398
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 399 LKSQVD----PKDIDITPIANAF 417
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 458 LKSQVD----PKDIDITPIANAF 476
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 458 LKSQVD----PKDIDITPIANAF 476
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 458 LKSQVD----PKDIDITPIANAF 476
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 8/143 (5%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMP---YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHN 397
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ G + F FS GKR C+G+ A + + L +++ +
Sbjct: 398 DKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFN 457
Query: 217 VTADISKIEFKMDVIMTPSDNCY 239
+ + + D+ +TP N +
Sbjct: 458 LKSQVD----PKDIDITPIANAF 476
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 53.2 bits (122), Expect = 8e-07
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L +IK +NY IP + ++ + +
Sbjct: 328 DRSHMP---YTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHD 384
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ GG F FS GKR C+G+ A + + L +++ +
Sbjct: 385 NKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFN 444
Query: 217 V 217
+
Sbjct: 445 L 445
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 53.2 bits (122), Expect = 8e-07
Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 1/120 (0%)
Query: 104 RLVYTEAVLKETLRLYPTIPLVL-RKPENEIKLKNYTIPANSNCVLGIYGLNRHPVWGPD 162
++ Y EAV+ E R IP+ L R+ + + K +++ +P + + + R P + +
Sbjct: 348 KMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSN 407
Query: 163 AHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYKVTADIS 222
F P+ +L+ G +AF FS+GKR C G+ A + + +++ +++ + S
Sbjct: 408 PQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKSSQS 467
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 53.2 bits (122), Expect = 8e-07
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 4/121 (3%)
Query: 98 EKHHHPRLVYTEAVLKETLRLYPTIPLVLRKPEN-EIKLKNYTIPANSNCVLGIYGLNRH 156
++ H P YT+AV+ E R +P L +IK +NY IP + ++ + +
Sbjct: 234 DRSHMP---YTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHD 290
Query: 157 PVWGPDAHTFRPERWLEPGGVPGNPNAFAGFSVGKRNCIGKTYALISTKIILAHLVRRYK 216
P+ F P +L+ GG F FS GKR C+G+ A + + L +++ +
Sbjct: 291 NKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFN 350
Query: 217 V 217
+
Sbjct: 351 L 351
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.137 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 37,784,434
Number of Sequences: 224733
Number of extensions: 1621196
Number of successful extensions: 3622
Number of sequences better than 10.0: 423
Number of HSP's better than 10.0 without gapping: 332
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 2854
Number of HSP's gapped (non-prelim): 567
length of query: 246
length of database: 73,234,838
effective HSP length: 88
effective length of query: 158
effective length of database: 53,458,334
effective search space: 8446416772
effective search space used: 8446416772
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 64 (29.9 bits)
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