Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002269-TA|BGIBMGA002269-PA|IPR002401|E-class P450, group
I, IPR001128|Cytochrome P450
(377 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 163 1e-39
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 163 1e-39
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 162 2e-39
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 162 2e-39
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 162 2e-39
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 162 2e-39
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 162 2e-39
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 161 3e-39
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 159 1e-38
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 159 1e-38
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 159 1e-38
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 159 1e-38
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 159 1e-38
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 159 2e-38
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 158 3e-38
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 158 3e-38
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 158 3e-38
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 153 1e-36
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 153 1e-36
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 153 1e-36
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 153 1e-36
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 153 1e-36
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 153 1e-36
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 153 1e-36
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 153 1e-36
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 149 2e-35
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 149 2e-35
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 149 2e-35
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 149 2e-35
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 142 2e-33
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 142 2e-33
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 142 2e-33
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 142 2e-33
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 142 2e-33
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 142 2e-33
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 141 3e-33
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 141 3e-33
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 141 3e-33
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 141 3e-33
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 141 4e-33
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 140 6e-33
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 140 6e-33
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 140 7e-33
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 140 1e-32
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 140 1e-32
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 139 1e-32
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 139 1e-32
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 139 1e-32
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 139 1e-32
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 138 4e-32
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 138 4e-32
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 137 5e-32
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 137 5e-32
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 137 5e-32
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 137 5e-32
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 136 9e-32
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 134 6e-31
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 134 6e-31
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 134 6e-31
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 134 6e-31
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 134 6e-31
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 134 6e-31
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 133 8e-31
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 132 2e-30
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 132 2e-30
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 132 2e-30
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 132 2e-30
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 132 2e-30
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 132 3e-30
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 132 3e-30
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 124 4e-28
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 112 2e-24
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 101 6e-21
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 101 6e-21
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 99 2e-20
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 99 2e-20
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 99 3e-20
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 99 3e-20
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 99 3e-20
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 99 3e-20
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 99 3e-20
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 99 3e-20
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 99 3e-20
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 99 3e-20
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 99 3e-20
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 99 3e-20
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 99 3e-20
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 99 3e-20
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 99 3e-20
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 98 4e-20
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 97 9e-20
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 95 3e-19
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 95 3e-19
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 94 8e-19
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 94 8e-19
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 94 8e-19
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 94 8e-19
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 90 1e-17
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 90 1e-17
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 90 1e-17
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 90 1e-17
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 90 1e-17
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 90 1e-17
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 90 1e-17
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 90 1e-17
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 90 1e-17
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 90 1e-17
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 85 5e-16
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 84 7e-16
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 84 9e-16
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 83 1e-15
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 83 1e-15
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 83 1e-15
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 83 1e-15
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 83 1e-15
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 81 6e-15
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 81 6e-15
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 81 6e-15
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 81 8e-15
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 79 3e-14
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 79 3e-14
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 78 6e-14
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 75 5e-13
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 75 5e-13
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 75 5e-13
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 74 1e-12
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 74 1e-12
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 74 1e-12
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 74 1e-12
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 73 1e-12
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 73 1e-12
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 73 2e-12
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 73 2e-12
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 73 2e-12
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 73 2e-12
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 73 2e-12
AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein. 73 2e-12
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 73 2e-12
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 72 3e-12
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 72 3e-12
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 72 3e-12
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 72 3e-12
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 72 3e-12
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 72 3e-12
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 72 3e-12
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 71 7e-12
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 69 2e-11
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 69 2e-11
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 69 2e-11
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 69 3e-11
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 69 3e-11
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 69 3e-11
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 69 3e-11
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 69 3e-11
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 69 3e-11
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 69 4e-11
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 69 4e-11
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 69 4e-11
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 67 8e-11
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 67 8e-11
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 67 8e-11
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 67 8e-11
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 67 8e-11
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 67 8e-11
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 67 8e-11
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 67 8e-11
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 67 8e-11
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 67 8e-11
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 67 8e-11
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 67 8e-11
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 67 1e-10
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 67 1e-10
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 67 1e-10
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 67 1e-10
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 67 1e-10
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 67 1e-10
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 67 1e-10
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 67 1e-10
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 66 1e-10
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 66 1e-10
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 66 1e-10
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 66 2e-10
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 66 2e-10
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 66 2e-10
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 66 2e-10
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 66 2e-10
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 66 2e-10
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 66 2e-10
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 66 2e-10
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 66 2e-10
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 66 2e-10
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 66 2e-10
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 66 2e-10
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 66 3e-10
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 66 3e-10
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 66 3e-10
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 66 3e-10
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 65 3e-10
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 65 3e-10
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 65 3e-10
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 65 3e-10
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 65 3e-10
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 65 3e-10
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 65 3e-10
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 65 3e-10
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 65 3e-10
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 65 3e-10
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 65 3e-10
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 65 3e-10
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 65 4e-10
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 65 4e-10
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 65 4e-10
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 64 6e-10
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 64 8e-10
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 64 8e-10
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 64 8e-10
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 64 8e-10
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 64 8e-10
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 64 8e-10
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 64 8e-10
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 64 8e-10
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 64 8e-10
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 64 8e-10
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 64 8e-10
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 64 8e-10
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 64 8e-10
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 64 8e-10
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 64 1e-09
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 63 1e-09
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 63 1e-09
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 63 1e-09
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 63 1e-09
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 63 1e-09
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 63 1e-09
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 63 1e-09
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 63 2e-09
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 63 2e-09
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 63 2e-09
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 63 2e-09
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 63 2e-09
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 63 2e-09
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 63 2e-09
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 63 2e-09
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 63 2e-09
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 62 2e-09
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 62 3e-09
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 62 3e-09
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 62 3e-09
AF221943-1|AAF86378.1| 175|Homo sapiens leukotriene B4 omega hy... 62 3e-09
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 62 4e-09
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 62 4e-09
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 61 5e-09
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 61 5e-09
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 61 5e-09
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 61 5e-09
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 61 5e-09
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 61 5e-09
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 61 7e-09
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 61 7e-09
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 61 7e-09
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 61 7e-09
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 61 7e-09
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 61 7e-09
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 61 7e-09
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 61 7e-09
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 61 7e-09
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 61 7e-09
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 61 7e-09
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 61 7e-09
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 61 7e-09
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 60 1e-08
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 60 1e-08
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 60 1e-08
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 60 1e-08
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 60 1e-08
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 60 1e-08
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 60 1e-08
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 60 1e-08
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 60 1e-08
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 60 1e-08
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 60 1e-08
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 60 1e-08
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 60 1e-08
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 60 1e-08
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 60 1e-08
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 60 1e-08
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 60 1e-08
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 1e-08
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 60 1e-08
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 60 1e-08
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 60 1e-08
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 60 1e-08
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 60 1e-08
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 60 1e-08
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 60 1e-08
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 60 1e-08
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 60 1e-08
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 60 2e-08
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 60 2e-08
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 60 2e-08
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 60 2e-08
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 59 2e-08
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 59 3e-08
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 58 4e-08
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 58 4e-08
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 58 4e-08
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 58 5e-08
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 58 5e-08
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 58 5e-08
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 58 5e-08
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 58 5e-08
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 58 7e-08
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 58 7e-08
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 58 7e-08
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 58 7e-08
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 57 9e-08
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 57 9e-08
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 57 9e-08
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 57 9e-08
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 57 9e-08
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 57 9e-08
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 57 9e-08
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 57 1e-07
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 57 1e-07
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 57 1e-07
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 57 1e-07
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 57 1e-07
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 56 2e-07
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 56 2e-07
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 56 2e-07
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 56 2e-07
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 56 2e-07
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 56 2e-07
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 56 2e-07
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 56 2e-07
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 56 2e-07
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 56 2e-07
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 56 2e-07
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 56 3e-07
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 55 5e-07
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 55 5e-07
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 54 6e-07
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 54 8e-07
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 53 1e-06
BC022851-1|AAH22851.1| 215|Homo sapiens CYP4A11 protein protein. 53 2e-06
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 52 3e-06
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 52 4e-06
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 52 4e-06
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 51 8e-06
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 49 3e-05
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 47 9e-05
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 46 3e-04
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 46 3e-04
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 46 3e-04
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 43 0.002
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 43 0.002
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 42 0.005
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 41 0.008
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 40 0.014
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 40 0.014
AB209749-1|BAD92986.1| 210|Homo sapiens cytochrome P450, family... 40 0.014
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 39 0.033
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 38 0.044
BC039317-1|AAH39317.2| 484|Homo sapiens coiled-coil domain cont... 37 0.13
AK093051-1|BAC04035.1| 484|Homo sapiens protein ( Homo sapiens ... 37 0.13
AF382188-1|AAK60542.1| 484|Homo sapiens NYD-SP28 protein. 37 0.13
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 37 0.13
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 34 0.72
M95678-1|AAA36453.1| 1181|Homo sapiens phospholipase C-beta-2 pr... 34 0.95
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 34 0.95
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 33 1.7
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 33 1.7
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 33 1.7
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 33 1.7
M83216-2|AAA58420.1| 538|Homo sapiens caldesmon protein. 32 2.9
M64110-1|AAA35636.1| 538|Homo sapiens caldesmon protein. 32 2.9
D90453-1|BAA14419.1| 532|Homo sapiens l-caldesmon II protein. 32 2.9
BC040354-1|AAH40354.1| 538|Homo sapiens caldesmon 1 protein. 32 2.9
BC014035-1|AAH14035.1| 314|Homo sapiens CALD1 protein protein. 32 2.9
AF247820-1|AAF69498.3| 481|Homo sapiens NAG22 protein protein. 32 2.9
BC069194-1|AAH69194.1| 1118|Homo sapiens PHLDB2 protein protein. 32 3.8
AJ496194-1|CAD42711.1| 1253|Homo sapiens LL5 beta protein protein. 32 3.8
AF506820-1|AAM33634.1| 1210|Homo sapiens hypothetical protein pr... 32 3.8
AB209903-1|BAD93140.1| 1259|Homo sapiens LL5 beta protein varian... 32 3.8
U63830-1|AAC50770.1| 425|Homo sapiens TRAF family member-associ... 31 6.7
U59863-1|AAC50681.1| 425|Homo sapiens I-TRAF protein. 31 6.7
BT009855-1|AAP88857.1| 119|Homo sapiens TRAF family member-asso... 31 6.7
BC067779-1|AAH67779.1| 425|Homo sapiens TANK protein protein. 31 6.7
BC003388-1|AAH03388.1| 119|Homo sapiens TRAF family member-asso... 31 6.7
L29016-1|AAA36448.1| 386|Homo sapiens prostanoid IP receptor pr... 31 8.8
D38127-1|BAA07325.1| 386|Homo sapiens prostacyclin receptor pro... 31 8.8
D29634-1|BAA06110.1| 386|Homo sapiens prostacyclin receptor pro... 31 8.8
D25418-1|BAA05008.1| 386|Homo sapiens prostacyclin receptor pro... 31 8.8
BC110342-1|AAI10343.1| 386|Homo sapiens prostaglandin I2 (prost... 31 8.8
BC075814-1|AAH75814.1| 386|Homo sapiens prostaglandin I2 (prost... 31 8.8
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 31 8.8
AY242134-1|AAO92301.1| 386|Homo sapiens prostaglandin I2 (prost... 31 8.8
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 31 8.8
AF225417-1|AAG09719.1| 779|Homo sapiens 88.8 kDa protein protein. 31 8.8
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 163 bits (395), Expect = 1e-39
Identities = 105/351 (29%), Positives = 177/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ +++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LR++P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 163 bits (395), Expect = 1e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAMWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 162 bits (393), Expect = 2e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 162 bits (393), Expect = 2e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 162 bits (393), Expect = 2e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 162 bits (393), Expect = 2e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 162 bits (393), Expect = 2e-39
Identities = 106/351 (30%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 161 bits (392), Expect = 3e-39
Identities = 105/351 (29%), Positives = 176/351 (50%), Gaps = 14/351 (3%)
Query: 24 YFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQM 83
+FY F W+GDGL+ SAG+ W RHR++L PAF +L Y +FN +S N++ A +
Sbjct: 123 FFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFN-DSVNIMHAKWQLL 181
Query: 84 KSGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILL 140
S F+ ++L TL S F + + +Y+ A+ EL A++++R ILL
Sbjct: 182 ASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILL 241
Query: 141 HNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXX 200
H F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 242 HIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDV 301
Query: 201 XXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSV 258
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 302 LLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQEL 361
Query: 259 CGD---SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSN 314
D + + D L H L + +KE+LRL+P PV+ R +I L + IP
Sbjct: 362 LKDREPKEIEWDDLAH--LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGII 419
Query: 315 CLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
CL+ ++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 420 CLISVFGTHHNPAMWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCI 469
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 159 bits (387), Expect = 1e-38
Identities = 105/348 (30%), Positives = 175/348 (50%), Gaps = 10/348 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SKGYARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D + +++ +L + +KE+LRL+P P V R +I L + IP CL+
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 423 SVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCI 469
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 159 bits (386), Expect = 1e-38
Identities = 105/348 (30%), Positives = 175/348 (50%), Gaps = 10/348 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D + +++ +L + +KE+LRL+P P V R +I L + IP CL+
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 423 SVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCI 469
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 159 bits (386), Expect = 1e-38
Identities = 105/348 (30%), Positives = 175/348 (50%), Gaps = 10/348 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D + +++ +L + +KE+LRL+P P V R +I L + IP CL+
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 423 SVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCI 469
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (386), Expect = 1e-38
Identities = 105/348 (30%), Positives = 175/348 (50%), Gaps = 10/348 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D + +++ +L + +KE+LRL+P P V R +I L + IP CL+
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 423 SVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCI 469
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 159 bits (386), Expect = 1e-38
Identities = 105/348 (30%), Positives = 175/348 (50%), Gaps = 10/348 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D + +++ +L + +KE+LRL+P P V R +I L + IP CL+
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPD-DPNAFAGFSVGKRNCI 364
++G + +P PD + P R+ +P + + P AF FS G RNCI
Sbjct: 423 SVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCI 469
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 159 bits (385), Expect = 2e-38
Identities = 107/347 (30%), Positives = 173/347 (49%), Gaps = 9/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR+LL PAF +L Y +FN +S +++ A +
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN-QSADIMHAKWRHLA 190
Query: 85 SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK---YMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S + + +K Y+ A+ EL A+ RR + +
Sbjct: 191 EGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHY 250
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
FIY SA ++ + + + + + I +RRAL+ +Q + A + KT
Sbjct: 251 LDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALR-RQGAEAWLKAKQGKTLDFIDVL 309
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T+S ++ ++ L YPE Q+K +EI+ V
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 260 -GDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
G +++ +L +T +KE+LR YP +V R+ +IKL + IP CL+
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
IYG + +P PD+ + P R+ P A+ FS G RNCI
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 158 bits (384), Expect = 3e-38
Identities = 107/347 (30%), Positives = 173/347 (49%), Gaps = 9/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR+LL PAF +L Y +FN +S +++ A +
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN-QSADIMHAKWRHLA 190
Query: 85 SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK---YMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S + + +K Y+ A+ EL A+ RR + +
Sbjct: 191 EGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHY 250
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
FIY SA ++ + + + + + I +RRAL+ +Q + A + KT
Sbjct: 251 LDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALR-QQGAEAWLKAKQGKTLDFIDVL 309
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T+S ++ ++ L YPE Q+K +EI+ V
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 260 -GDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
G +++ +L +T +KE+LR YP +V R+ +IKL + IP CL+
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
IYG + +P PD+ + P R+ P A+ FS G RNCI
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 158 bits (384), Expect = 3e-38
Identities = 107/347 (30%), Positives = 173/347 (49%), Gaps = 9/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR+LL PAF +L Y +FN +S +++ A +
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN-QSADIMHAKWRHLA 190
Query: 85 SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK---YMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S + + +K Y+ A+ EL A+ RR + +
Sbjct: 191 EGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHY 250
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
FIY SA ++ + + + + + I +RRAL+ +Q + A + KT
Sbjct: 251 LDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALR-QQGAEAWLKAKQGKTLDFIDVL 309
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T+S ++ ++ L YPE Q+K +EI+ V
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 260 -GDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
G +++ +L +T +KE+LR YP +V R+ +IKL + IP CL+
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
IYG + +P PD+ + P R+ P A+ FS G RNCI
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 158 bits (384), Expect = 3e-38
Identities = 107/347 (30%), Positives = 173/347 (49%), Gaps = 9/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR+LL PAF +L Y +FN +S +++ A +
Sbjct: 132 FYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHFDILKPYMKIFN-QSADIMHAKWRHLA 190
Query: 85 SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK---YMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S + + +K Y+ A+ EL A+ RR + +
Sbjct: 191 EGSAVSLDMFEHISLMTLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHY 250
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
FIY SA ++ + + + + + I +RRAL+ +Q + A + KT
Sbjct: 251 LDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALR-QQGAEAWLKAKQGKTLDFIDVL 309
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T+S ++ ++ L YPE Q+K +EI+ V
Sbjct: 310 LLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVM 369
Query: 260 -GDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
G +++ +L +T +KE+LR YP +V R+ +IKL + IP CL+
Sbjct: 370 KGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLV 429
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
IYG + +P PD+ + P R+ P A+ FS G RNCI
Sbjct: 430 SIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 153 bits (371), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 124 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 183
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 184 EGSSCLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 243 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 469
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 153 bits (371), Expect = 1e-36
Identities = 101/347 (29%), Positives = 170/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR++L PAF +L Y +FN+ S N++ ++
Sbjct: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNK-SVNIMHDKWQRLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F E + +Y+ A+ EL A + +R Q ILLH
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y L+ ++ + ++ I +RR L + + +N S+
Sbjct: 243 TDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLR-KTENEIKLKNYTIPANSNCLL 317
D + +++ +L + +KE+LRL+P PV+ R T++ + IP CL+
Sbjct: 363 KDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ + P AF FS G RNCI
Sbjct: 423 NIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCI 469
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 153 bits (371), Expect = 1e-36
Identities = 101/347 (29%), Positives = 170/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ S G+ W RHR++L PAF +L Y +FN+ S N++ ++
Sbjct: 124 FYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNK-SVNIMHDKWQRLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F E + +Y+ A+ EL A + +R Q ILLH
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y L+ ++ + ++ I +RR L + + +N S+
Sbjct: 243 TDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLR-KTENEIKLKNYTIPANSNCLL 317
D + +++ +L + +KE+LRL+P PV+ R T++ + IP CL+
Sbjct: 363 KDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ + P AF FS G RNCI
Sbjct: 423 NIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCI 469
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 153 bits (371), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 58 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 117
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 118 EGSSCLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 176
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 177 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 236
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 237 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 296
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 297 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 356
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 357 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 403
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 153 bits (370), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 124 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 183
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 184 EGSSRLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 243 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 469
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 153 bits (370), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 124 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 183
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 184 EGSSRLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 243 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 469
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 153 bits (370), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 124 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 183
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 184 EGSSRLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 243 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 469
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 153 bits (370), Expect = 1e-36
Identities = 96/347 (27%), Positives = 169/347 (48%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
F +F W+G+G++ S G+ W RHR++L PAF +L Y +FN+ + ++ +
Sbjct: 124 FIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLAS 183
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
G + F+ ++L TL S F + + +Y+ + EL A++ +R Q+IL H
Sbjct: 184 EGSSRLD-MFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQH 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK--QESHENGCASEKKTQXXXX 199
F+Y LS ++ + ++ I +RR L + + ++ S+
Sbjct: 243 MDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+A +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLL 317
D D +++ +L + +KE+LRL+P AP + R +I L + IP CL+
Sbjct: 363 KDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I G++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 DIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCI 469
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 92/358 (25%), Positives = 163/358 (45%), Gaps = 6/358 (1%)
Query: 13 LTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRES 72
+ ++ ++ K Y+F W+G GL+TS G W+ RK+L P F +L + + N ++
Sbjct: 111 ILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQA 170
Query: 73 RNLISAIEIQMKSGPVLITAAFKEMALKTLLSTAFGIE-EEECDFNQKYMHAVDELMAVL 131
L+ +E + AL + TA G + + + +Y+ AV + ++
Sbjct: 171 NILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
Query: 132 TRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENG---C 188
RR++ L Y + + + ++ + +N I + + ++ +G
Sbjct: 231 FRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSVIAERANEMNANEDCRGDGRGSA 290
Query: 189 ASEKKTQXXXXXXXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPE 246
S+ K + E + ++IR EVDTF+ G T++ + + +LGS PE
Sbjct: 291 PSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPE 350
Query: 247 IQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN 306
+Q KV E+ V G SD +L Y E V+KETLRL+P P+ R + ++
Sbjct: 351 VQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG 410
Query: 307 YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y + + ++ Y L+R P + P+ F+PER+ P A+ FS G RNCI
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCI 468
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 92/358 (25%), Positives = 163/358 (45%), Gaps = 6/358 (1%)
Query: 13 LTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRES 72
+ ++ ++ K Y+F W+G GL+TS G W+ RK+L P F +L + + N ++
Sbjct: 111 ILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQA 170
Query: 73 RNLISAIEIQMKSGPVLITAAFKEMALKTLLSTAFGIE-EEECDFNQKYMHAVDELMAVL 131
L+ +E + AL + TA G + + + +Y+ AV + ++
Sbjct: 171 NILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
Query: 132 TRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENG---C 188
RR++ L Y + + + ++ + +N I + + ++ +G
Sbjct: 231 FRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSVIAERANEMNANEDCRGDGRGSA 290
Query: 189 ASEKKTQXXXXXXXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPE 246
S+ K + E + ++IR EVDTF+ G T++ + + +LGS PE
Sbjct: 291 PSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPE 350
Query: 247 IQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN 306
+Q KV E+ V G SD +L Y E V+KETLRL+P P+ R + ++
Sbjct: 351 VQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG 410
Query: 307 YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y + + ++ Y L+R P + P+ F+PER+ P A+ FS G RNCI
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCI 468
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 149 bits (360), Expect = 2e-35
Identities = 92/358 (25%), Positives = 163/358 (45%), Gaps = 6/358 (1%)
Query: 13 LTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRES 72
+ ++ ++ K Y+F W+G GL+TS G W+ RK+L P F +L + + N ++
Sbjct: 89 ILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQA 148
Query: 73 RNLISAIEIQMKSGPVLITAAFKEMALKTLLSTAFGIE-EEECDFNQKYMHAVDELMAVL 131
L+ +E + AL + TA G + + + +Y+ AV + ++
Sbjct: 149 NILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 208
Query: 132 TRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENG---C 188
RR++ L Y + + + ++ + +N I + + ++ +G
Sbjct: 209 FRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSVIAERANEMNANEDCRGDGRGSA 268
Query: 189 ASEKKTQXXXXXXXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPE 246
S+ K + E + ++IR EVDTF+ G T++ + + +LGS PE
Sbjct: 269 PSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPE 328
Query: 247 IQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN 306
+Q KV E+ V G SD +L Y E V+KETLRL+P P+ R + ++
Sbjct: 329 VQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG 388
Query: 307 YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y + + ++ Y L+R P + P+ F+PER+ P A+ FS G RNCI
Sbjct: 389 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCI 446
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 149 bits (360), Expect = 2e-35
Identities = 92/358 (25%), Positives = 163/358 (45%), Gaps = 6/358 (1%)
Query: 13 LTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRES 72
+ ++ ++ K Y+F W+G GL+TS G W+ RK+L P F +L + + N ++
Sbjct: 111 ILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQA 170
Query: 73 RNLISAIEIQMKSGPVLITAAFKEMALKTLLSTAFGIE-EEECDFNQKYMHAVDELMAVL 131
L+ +E + AL + TA G + + + +Y+ AV + ++
Sbjct: 171 NILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMI 230
Query: 132 TRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENG---C 188
RR++ L Y + + + ++ + +N I + + ++ +G
Sbjct: 231 FRRIKMPWLWLDLWYLMFKEGWEHKKSLKILHTFTNSVIAERANEMNANEDCRGDGRGSA 290
Query: 189 ASEKKTQXXXXXXXXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPE 246
S+ K + E + ++IR EVDTF+ G T++ + + +LGS PE
Sbjct: 291 PSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPE 350
Query: 247 IQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN 306
+Q KV E+ V G SD +L Y E V+KETLRL+P P+ R + ++
Sbjct: 351 VQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAG 410
Query: 307 YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y + + ++ Y L+R P + P+ F+PER+ P A+ FS G RNCI
Sbjct: 411 YRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCI 468
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 142 bits (343), Expect = 2e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 141 bits (342), Expect = 3e-33
Identities = 97/345 (28%), Positives = 157/345 (45%), Gaps = 10/345 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHN 142
G I MAL TL+ FG + ++ Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHN 234
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 DFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLG 292
Query: 203 XXXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD 352
Query: 262 SD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGI 319
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + I
Sbjct: 353 QDFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHI 410
Query: 320 YGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 YALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 141 bits (342), Expect = 3e-33
Identities = 97/345 (28%), Positives = 157/345 (45%), Gaps = 10/345 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHN 142
G I MAL TL+ FG + ++ Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHN 234
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 DFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLG 292
Query: 203 XXXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD 352
Query: 262 SD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGI 319
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + I
Sbjct: 353 QDFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHI 410
Query: 320 YGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 YALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 141 bits (342), Expect = 3e-33
Identities = 97/345 (28%), Positives = 157/345 (45%), Gaps = 10/345 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHN 142
G I MAL TL+ FG + ++ Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHN 234
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 DFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLG 292
Query: 203 XXXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD 352
Query: 262 SD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGI 319
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + I
Sbjct: 353 QDFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHI 410
Query: 320 YGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 YALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 141 bits (342), Expect = 3e-33
Identities = 97/345 (28%), Positives = 157/345 (45%), Gaps = 10/345 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHN 142
G I MAL TL+ FG + ++ Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHN 234
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 DFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLG 292
Query: 203 XXXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 ARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGD 352
Query: 262 SD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGI 319
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + I
Sbjct: 353 QDFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHI 410
Query: 320 YGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
Y L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 YALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 455
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 141 bits (341), Expect = 4e-33
Identities = 97/344 (28%), Positives = 156/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 140 bits (340), Expect = 6e-33
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 140 bits (340), Expect = 6e-33
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 140 bits (339), Expect = 7e-33
Identities = 97/362 (26%), Positives = 169/362 (46%), Gaps = 8/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + + + R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLSHQHTRPKVIQLRKAQLQKEGE 280
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 281 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 340
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 341 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 399
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 400 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 457
Query: 363 CI 364
CI
Sbjct: 458 CI 459
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 140 bits (338), Expect = 1e-32
Identities = 97/344 (28%), Positives = 155/344 (45%), Gaps = 9/344 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAWE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXX 203
FIY L+ ++ + +++ I ++ AL++ E + +
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGA 292
Query: 204 XXXXE-AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ +D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD
Sbjct: 293 RDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQ 352
Query: 263 D-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIY 320
D D L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY
Sbjct: 353 DFFQWDDL--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIY 410
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+R+ PD F R+ P AF FS G RNCI
Sbjct: 411 ALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 454
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 140 bits (338), Expect = 1e-32
Identities = 91/347 (26%), Positives = 163/347 (46%), Gaps = 8/347 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISA--IEIQ 82
FY+ W+GDGL+ S G+ W+ HR+LL PAF +L Y +F++ S N++ A +
Sbjct: 124 FYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSK-SANIMHAKWQRLA 182
Query: 83 MKSGPVL-ITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
M+ L + M L +L F + + +Y+ A+ EL A++ +R +
Sbjct: 183 MEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFFRY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQ--XXXX 199
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 KDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 200 XXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKL-KNYTIPANSNCLL 317
D + +++ +L + LKE+LRL+P P R ++ L + IP + C +
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNI 422
Query: 318 GIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
I+ ++ +P PD + P R+ P AF FS G RNCI
Sbjct: 423 NIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCI 469
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 139 bits (337), Expect = 1e-32
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 139 bits (337), Expect = 1e-32
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 139 bits (337), Expect = 1e-32
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 139 bits (337), Expect = 1e-32
Identities = 98/362 (27%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 138 bits (333), Expect = 4e-32
Identities = 95/362 (26%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G L+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDSKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ M L T++ +AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L +++ R++N N IY L++ + + +++ I ++ L+ + E
Sbjct: 221 ISDLSSLVFCRMRNAFHENDAIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQTEGEL 280
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 281 -EKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI + GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 138 bits (333), Expect = 4e-32
Identities = 97/362 (26%), Positives = 171/362 (47%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRL+P P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 137 bits (332), Expect = 5e-32
Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 7/343 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + + R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQ 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
++K S+ + + + + + K I ++ +LK+K + ++ +
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLK--QDTTQKRRWDFLDILLSA 291
Query: 203 XXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ F++ +++ EV TF+ AG T+S ++ ++ L YPE Q + EI+ + GD
Sbjct: 292 KSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDG 351
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLLGIYG 321
+ + ++ YT +KE LRLY + R + I + ++PA + I+
Sbjct: 352 -SSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWA 410
Query: 322 LNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+ +P + D F P R+ P AF FS G RNCI
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCI 453
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 137 bits (332), Expect = 5e-32
Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 7/343 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + + R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQ 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
++K S+ + + + + + K I ++ +LK+K + ++ +
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLK--QDTTQKRRWDFLDILLSA 291
Query: 203 XXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ F++ +++ EV TF+ AG T+S ++ ++ L YPE Q + EI+ + GD
Sbjct: 292 KSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDG 351
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLLGIYG 321
+ + ++ YT +KE LRLY + R + I + ++PA + I+
Sbjct: 352 -SSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWA 410
Query: 322 LNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+ +P + D F P R+ P AF FS G RNCI
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCI 453
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 137 bits (332), Expect = 5e-32
Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 7/343 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + + R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQ 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
++K S+ + + + + + K I ++ +LK+K + ++ +
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLK--QDTTQKRRWDFLDILLSA 291
Query: 203 XXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ F++ +++ EV TF+ AG T+S ++ ++ L YPE Q + EI+ + GD
Sbjct: 292 KSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDG 351
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLLGIYG 321
+ + ++ YT +KE LRLY + R + I + ++PA + I+
Sbjct: 352 -SSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWA 410
Query: 322 LNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+ +P + D F P R+ P AF FS G RNCI
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCI 453
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 137 bits (332), Expect = 5e-32
Identities = 87/343 (25%), Positives = 160/343 (46%), Gaps = 7/343 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + + R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQ 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
++K S+ + + + + + K I ++ +LK+K + ++ +
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLK--QDTTQKRRWDFLDILLSA 291
Query: 203 XXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDS 262
+ F++ +++ EV TF+ AG T+S ++ ++ L YPE Q + EI+ + GD
Sbjct: 292 KSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDG 351
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLLGIYG 321
+ + ++ YT +KE LRLY + R + I + ++PA + I+
Sbjct: 352 -SSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWA 410
Query: 322 LNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
L+ +P + D F P R+ P AF FS G RNCI
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCI 453
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 136 bits (330), Expect = 9e-32
Identities = 97/362 (26%), Positives = 170/362 (46%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G L+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYKFLAPWIGYSLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ M L T++ +AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEFFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 93 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 152
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 211
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 212 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 271
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 272 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 330
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 331 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449
Query: 359 GKRNCI 364
G RNCI
Sbjct: 450 GSRNCI 455
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 93 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 152
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 211
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 212 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 271
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 272 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 330
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 331 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449
Query: 359 GKRNCI 364
G RNCI
Sbjct: 450 GSRNCI 455
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 93 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 152
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 211
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 212 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 271
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 272 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 330
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 331 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449
Query: 359 GKRNCI 364
G RNCI
Sbjct: 450 GSRNCI 455
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 93 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 152
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 211
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 212 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 271
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 272 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 330
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 331 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449
Query: 359 GKRNCI 364
G RNCI
Sbjct: 450 GSRNCI 455
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 93 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 152
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 153 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 211
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 212 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 271
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 272 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 330
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 331 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 389
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 390 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 449
Query: 359 GKRNCI 364
G RNCI
Sbjct: 450 GSRNCI 455
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 134 bits (323), Expect = 6e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 28 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 87
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 88 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFS-KETNCQTNSTHDP 146
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 147 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 206
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 207 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 265
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 266 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 324
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 325 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 384
Query: 359 GKRNCI 364
G RNCI
Sbjct: 385 GSRNCI 390
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 133 bits (322), Expect = 8e-31
Identities = 92/366 (25%), Positives = 166/366 (45%), Gaps = 10/366 (2%)
Query: 6 ITDPEDNLTV-ANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIY 64
I DP+ T+ + + + Y +F+ +G GL G W +HR+LL P F +L Y
Sbjct: 92 IYDPDYAKTLLSRTDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAY 151
Query: 65 TAVFNRESRNLISAIE--IQMKSGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK--- 119
V + ++ E + V + M+L ++ AF +E C N
Sbjct: 152 IEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIVMKCAFS-KETNCQTNSTHDP 210
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKN 179
Y A+ EL ++ RL ++L H+ I+KLS + +L + ++ I ++++L+
Sbjct: 211 YAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQA 270
Query: 180 KQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVM 239
+ +N + + +F+D ++ +EV TF+ AG T + ++ ++
Sbjct: 271 GVKQ-DNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILY 329
Query: 240 VLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTE 299
L PE Q++ +E++ + GD + + Q + YT +KET RL P P + R
Sbjct: 330 CLALNPEHQERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLS 388
Query: 300 NEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSV 358
+ + T+PA +L I+GL+ +P + F P R+ + P A+ FS
Sbjct: 389 KPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSA 448
Query: 359 GKRNCI 364
G RNCI
Sbjct: 449 GSRNCI 454
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 132 bits (319), Expect = 2e-30
Identities = 94/337 (27%), Positives = 153/337 (45%), Gaps = 10/337 (2%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGPVL-ITA 92
G GL+ G W +HRKLL P F +L Y AVF +R ++ E + + G I
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 93 AFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHNSFIYKLSA 150
MAL TL+ FG + ++ Y AV +L ++ +RL + HN FIY L+
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 151 LKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE-A 209
++ + +++ I ++ AL++ E + + +
Sbjct: 228 HGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGARDEDDIK 285
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSD-ADVDK 268
+D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD D D
Sbjct: 286 LSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDD 345
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIYGLNRHPV 327
L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY L+R+
Sbjct: 346 L--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSA 403
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
PD F R+ P AF FS G RNCI
Sbjct: 404 VWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 132 bits (319), Expect = 2e-30
Identities = 94/337 (27%), Positives = 153/337 (45%), Gaps = 10/337 (2%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGPVL-ITA 92
G GL+ G W +HRKLL P F +L Y AVF +R ++ E + + G I
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 93 AFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHNSFIYKLSA 150
MAL TL+ FG + ++ Y AV +L ++ +RL + HN FIY L+
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 151 LKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE-A 209
++ + +++ I ++ AL++ E + + +
Sbjct: 228 HGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGARDEDDIK 285
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSD-ADVDK 268
+D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD D D
Sbjct: 286 LSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDD 345
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIYGLNRHPV 327
L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY L+R+
Sbjct: 346 L--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSA 403
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
PD F R+ P AF FS G RNCI
Sbjct: 404 VWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 132 bits (319), Expect = 2e-30
Identities = 94/337 (27%), Positives = 153/337 (45%), Gaps = 10/337 (2%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGPVL-ITA 92
G GL+ G W +HRKLL P F +L Y AVF +R ++ E + + G I
Sbjct: 108 GRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFC 167
Query: 93 AFKEMALKTLLSTAFGIEEEECDFNQ--KYMHAVDELMAVLTRRLQNILLHNSFIYKLSA 150
MAL TL+ FG + ++ Y AV +L ++ +RL + HN FIY L+
Sbjct: 168 DVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTP 227
Query: 151 LKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE-A 209
++ + +++ I ++ AL++ E + + +
Sbjct: 228 HGRRFLRACQVAHDHTDQVIRERKAALQD--EKVRKKIQNRRHLDFLDILLGARDEDDIK 285
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSD-ADVDK 268
+D ++R EVDTF+ G T++ ++ + + YPE Q + +E++ + GD D D
Sbjct: 286 LSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDD 345
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK-LKNYTIPANSNCLLGIYGLNRHPV 327
L ++ Y +KE+ RLYP P V R+ + + ++PA S + IY L+R+
Sbjct: 346 L--GKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSA 403
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
PD F R+ P AF FS G RNCI
Sbjct: 404 VWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCI 440
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 132 bits (319), Expect = 2e-30
Identities = 95/362 (26%), Positives = 170/362 (46%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + +G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ +AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L +++ ++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI + GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 132 bits (319), Expect = 2e-30
Identities = 95/362 (26%), Positives = 170/362 (46%), Gaps = 9/362 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + +G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ +AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L +++ ++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI + GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRN 362
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G RN
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRF-APGSA-QHSHAFLPFSGGSRN 456
Query: 363 CI 364
CI
Sbjct: 457 CI 458
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 132 bits (318), Expect = 3e-30
Identities = 95/359 (26%), Positives = 168/359 (46%), Gaps = 9/359 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKR 361
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G R
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSR 455
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 132 bits (318), Expect = 3e-30
Identities = 95/359 (26%), Positives = 168/359 (46%), Gaps = 9/359 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + W+G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L ++ R++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI S+ GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKR 361
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G R
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF-APGSA-QHSHAFLPFSGGSR 455
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 124 bits (300), Expect = 4e-28
Identities = 92/359 (25%), Positives = 167/359 (46%), Gaps = 9/359 (2%)
Query: 8 DPED-NLTVANGELQKHYFYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA 66
DP+ + + + + H Y+F + +G GL+ G+TW +HR++L PAF +L Y
Sbjct: 101 DPDYMKVILGRSDPKSHGSYKFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVG 160
Query: 67 VFNRESRNLISA-IEIQMKSGPVLITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHA 123
+ R ++ E+ + P+ + M L T++ +AF + + D N Q Y+ A
Sbjct: 161 LMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSYIQA 220
Query: 124 VDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQES 183
+ +L +++ ++N N IY L++ + + +++ I R+A K+
Sbjct: 221 ISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVI-QLRKAQLQKEGE 279
Query: 184 HENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGS 243
E +DK++R EVDTF+ G T++ ++ ++ L +
Sbjct: 280 LEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALAT 339
Query: 244 YPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIK 303
+P+ Q++ +EI + GD A + ++ YT +KE LRLYP P + R+ +
Sbjct: 340 HPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVT 398
Query: 304 LKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKR 361
+ ++P LL IYGL+ +P P+ F P R+ PG +AF FS G R
Sbjct: 399 FPDGRSLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRF-APGSA-QHSHAFLPFSGGSR 455
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 112 bits (270), Expect = 2e-24
Identities = 76/267 (28%), Positives = 133/267 (49%), Gaps = 7/267 (2%)
Query: 25 FYQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMK 84
FY F W+GDGL+ SAGE W RHR++L PAF +L Y +FN ES N++ A +
Sbjct: 124 FYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFN-ESVNIMHAKWQLLA 182
Query: 85 SGPVLITAAFKEMALKTLLS---TAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLH 141
S F+ ++L TL S F + + +Y+ A+ EL A++T+R Q ILL+
Sbjct: 183 SEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLY 242
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
F+Y L+ ++ + ++ I +RR L ++ ++ KT
Sbjct: 243 IDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVL 302
Query: 202 XXXXXXEA--FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC 259
+ +D++IR E DTF+ G T++ ++ V+ L +PE Q++ QE++ +
Sbjct: 303 LLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELL 362
Query: 260 GDSD-ADVDKLQHPRLVYTEAVLKETL 285
D + +++ +L + +KE+L
Sbjct: 363 KDREPKEIEWDDLAQLPFLTMCIKESL 389
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 101 bits (241), Expect = 6e-21
Identities = 92/339 (27%), Positives = 140/339 (41%), Gaps = 18/339 (5%)
Query: 28 FTSNWVGDGLVTSAG-ETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSG 86
F G GLV+ E W + R++++ AFS+ L FN ++ L+ +E +
Sbjct: 116 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQ 175
Query: 87 -PVLITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFI 145
PV + A+ L AFG+E QK + +LM +N L F+
Sbjct: 176 TPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLA--KFL 233
Query: 146 YKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXX 205
++ E I + + + +R ALK +E + K +
Sbjct: 234 PGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEG-------- 285
Query: 206 XXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDAD 265
A D+ + + TF AG TS+ + VM L PEI ++ E+ V G S
Sbjct: 286 ---AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRY 341
Query: 266 VDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRH 325
+D RL Y VLKE+LRLYP A R E E + +P N+ L Y + R
Sbjct: 342 LDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRM 401
Query: 326 PVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ D TF P+R+ G P + FS+G R+CI
Sbjct: 402 DTYFEDPLTFNPDRF--GPGAPKPRFTYFPFSLGHRSCI 438
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 101 bits (241), Expect = 6e-21
Identities = 92/339 (27%), Positives = 140/339 (41%), Gaps = 18/339 (5%)
Query: 28 FTSNWVGDGLVTSAG-ETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSG 86
F G GLV+ E W + R++++ AFS+ L FN ++ L+ +E +
Sbjct: 116 FGERLFGQGLVSECNYERWHKQRRVIDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQ 175
Query: 87 -PVLITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFI 145
PV + A+ L AFG+E QK + +LM +N L F+
Sbjct: 176 TPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVKLMLEGITASRNTLA--KFL 233
Query: 146 YKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXX 205
++ E I + + + +R ALK +E + K +
Sbjct: 234 PGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEG-------- 285
Query: 206 XXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDAD 265
A D+ + + TF AG TS+ + VM L PEI ++ E+ V G S
Sbjct: 286 ---AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRY 341
Query: 266 VDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRH 325
+D RL Y VLKE+LRLYP A R E E + +P N+ L Y + R
Sbjct: 342 LDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRM 401
Query: 326 PVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ D TF P+R+ G P + FS+G R+CI
Sbjct: 402 DTYFEDPLTFNPDRF--GPGAPKPRFTYFPFSLGHRSCI 438
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 99.1 bits (236), Expect = 2e-20
Identities = 86/372 (23%), Positives = 163/372 (43%), Gaps = 20/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 K-YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRAL 177
++ +L+ L L F + + L+ + I + N R+++
Sbjct: 201 DPFVENTKKLLRF--DFLDPFFLSIIFPFLIPILE------VLNICVFPREVTNFLRKSV 252
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 253 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 312
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 313 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 370
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 371 RLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYT 430
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 431 YTPFGSGPRNCI 442
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 99.1 bits (236), Expect = 2e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGCETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYT 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 98.7 bits (235), Expect = 3e-20
Identities = 86/369 (23%), Positives = 163/369 (44%), Gaps = 14/369 (3%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + + G PV + F ++ + T+FG+ + + Q
Sbjct: 141 KLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQ 200
Query: 119 K-YMHAVDELM--AVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRR 175
++ + + + L +I+L AL +TI +S K++N ++
Sbjct: 201 DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPK-DTINFLS-KSVNRMKK 258
Query: 176 ALKNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMT 235
+ N ++ H + +A +D E+ + FI AG T+S +++
Sbjct: 259 SRLNDKQKHR---LDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLS 315
Query: 236 VVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVL 295
+ L ++P++Q K+ +EI +V + A ++ Y + V+ ETLRL+P+A +
Sbjct: 316 FTLYELATHPDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLE 374
Query: 296 RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAG 355
R + ++++ IP S ++ Y L+ P + + FRPER+ + DP +
Sbjct: 375 RTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-SIDPYIYTP 433
Query: 356 FSVGKRNCI 364
F G RNCI
Sbjct: 434 FGTGPRNCI 442
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 98.7 bits (235), Expect = 3e-20
Identities = 86/369 (23%), Positives = 163/369 (44%), Gaps = 14/369 (3%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + + G PV + F ++ + T+FG+ + + Q
Sbjct: 141 KLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQ 200
Query: 119 K-YMHAVDELM--AVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRR 175
++ + + + L +I+L AL +TI +S K++N ++
Sbjct: 201 DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPK-DTINFLS-KSVNRMKK 258
Query: 176 ALKNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMT 235
+ N ++ H + +A +D E+ + FI AG T+S +++
Sbjct: 259 SRLNDKQKHR---LDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLS 315
Query: 236 VVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVL 295
+ L ++P++Q K+ +EI +V + A ++ Y + V+ ETLRL+P+A +
Sbjct: 316 FTLYELATHPDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLE 374
Query: 296 RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAG 355
R + ++++ IP S ++ Y L+ P + + FRPER+ + DP +
Sbjct: 375 RTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-SIDPYIYTP 433
Query: 356 FSVGKRNCI 364
F G RNCI
Sbjct: 434 FGTGPRNCI 442
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 8 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 67
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 68 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 127
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 128 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 180
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 181 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 240
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 241 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 298
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 299 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 358
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 359 YTPFGSGPRNCI 370
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 98.7 bits (235), Expect = 3e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 98.7 bits (235), Expect = 3e-20
Identities = 86/369 (23%), Positives = 163/369 (44%), Gaps = 14/369 (3%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + + G PV + F ++ + T+FG+ + + Q
Sbjct: 141 KLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQ 200
Query: 119 K-YMHAVDELM--AVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRR 175
++ + + + L +I+L AL +TI +S K++N ++
Sbjct: 201 DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPK-DTINFLS-KSVNRMKK 258
Query: 176 ALKNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMT 235
+ N ++ H + +A +D E+ + FI AG T+S +++
Sbjct: 259 SRLNDKQKHR---LDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLS 315
Query: 236 VVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVL 295
+ L ++P++Q K+ +EI +V + A ++ Y + V+ ETLRL+P+A +
Sbjct: 316 FTLYELATHPDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLE 374
Query: 296 RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAG 355
R + ++++ IP S ++ Y L+ P + + FRPER+ + DP +
Sbjct: 375 RTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-SIDPYIYTP 433
Query: 356 FSVGKRNCI 364
F G RNCI
Sbjct: 434 FGTGPRNCI 442
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 98.3 bits (234), Expect = 4e-20
Identities = 85/372 (22%), Positives = 161/372 (43%), Gaps = 19/372 (5%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + ++G PV + F ++ + ST+FG+ + + Q
Sbjct: 141 KLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQ 200
Query: 119 KYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IETIMAMSNKAINSKRRAL 177
+ T++L + F ++ L + I + N R+++
Sbjct: 201 -------DPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSV 253
Query: 178 KNKQESHENGCASEK----KTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQL 233
K +ES + + +A +D E+ + FI AG T+S +
Sbjct: 254 KRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSV 313
Query: 234 MTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAP 292
++ ++ L ++P++Q K+ +EI +V + + D + ++ Y + V+ ETLRL+PIA
Sbjct: 314 LSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QMEYLDMVVNETLRLFPIAM 371
Query: 293 VVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNA 352
+ R + ++++ IP ++ Y L+R P + + F PER+ + DP
Sbjct: 372 RLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYI 431
Query: 353 FAGFSVGKRNCI 364
+ F G RNCI
Sbjct: 432 YTPFGSGPRNCI 443
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 97.1 bits (231), Expect = 9e-20
Identities = 86/369 (23%), Positives = 162/369 (43%), Gaps = 14/369 (3%)
Query: 3 ITVITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQ 59
+ ITDP+ TV E + + + VG + + E WKR R LL+P F+
Sbjct: 81 VLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISLAEDEEWKRIRPLLSPTFTSG 140
Query: 60 MLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQ 118
L + + L+ + + + G PV + F ++ + T+FG+ + + Q
Sbjct: 141 KLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYSMDVITGTSFGVNIDSLNNPQ 200
Query: 119 K-YMHAVDELM--AVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRR 175
++ + + + L +I+L AL +TI +S K++N ++
Sbjct: 201 DPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSLFPK-DTINFLS-KSVNRMKK 258
Query: 176 ALKNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMT 235
+ N ++ H + +A +D E+ + FI AG T+S +++
Sbjct: 259 SRLNDKQKHR---LDFLQLMIDSQNSKETESHKALSDLELAAQSIIFIFAGYETTSSVLS 315
Query: 236 VVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVL 295
+ L ++P++Q K+ +EI +V + A ++ Y + V+ ETLRL+P+A +
Sbjct: 316 FTLYELATHPDVQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLE 374
Query: 296 RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAG 355
R ++++ IP S ++ Y L+ P + + FRPER+ + DP +
Sbjct: 375 RTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-SIDPYIYTP 433
Query: 356 FSVGKRNCI 364
F G RNCI
Sbjct: 434 FGTGPRNCI 442
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 95.5 bits (227), Expect = 3e-19
Identities = 79/330 (23%), Positives = 146/330 (44%), Gaps = 17/330 (5%)
Query: 43 ETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKT 101
E WKR R LL+P F+ L + + L+ + + ++G PV + F ++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDV 183
Query: 102 LLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IE 160
+ S++FG+ + + Q D L+ T++L + F ++ L +
Sbjct: 184 ITSSSFGVNVDSLNNPQ------DPLVE-NTKKLLRFDFLDPFFLSITVFPFLIPILEVL 236
Query: 161 TIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE-----AFTDKEI 215
I + N R+A+K +ES + E A +D E+
Sbjct: 237 NICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLEL 296
Query: 216 RNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC-GDSDADVDKLQHPRL 274
+ FI AG T+S +++ ++ L ++P++Q K+ +EI +V + D + ++
Sbjct: 297 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QM 354
Query: 275 VYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHT 334
Y + V+ ETLRL+PIA + R + ++++ IP ++ Y L+R P + +
Sbjct: 355 EYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEK 414
Query: 335 FRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F PER+ + DP + F G RNCI
Sbjct: 415 FLPERFSKKNKDNIDPYIYTPFGSGPRNCI 444
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 95.5 bits (227), Expect = 3e-19
Identities = 79/330 (23%), Positives = 146/330 (44%), Gaps = 17/330 (5%)
Query: 43 ETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKT 101
E WKR R LL+P F+ L + + L+ + + ++G PV + F ++
Sbjct: 124 EEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRRERETGKPVTLKDVFGAYSMDV 183
Query: 102 LLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDEL-IE 160
+ S++FG+ + + Q D L+ T++L + F ++ L +
Sbjct: 184 ITSSSFGVNVDSLNNPQ------DPLVE-NTKKLLRFDFLDPFFLSITVFPFLIPILEVL 236
Query: 161 TIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE-----AFTDKEI 215
I + N R+A+K +ES + E A +D E+
Sbjct: 237 NICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLEL 296
Query: 216 RNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVC-GDSDADVDKLQHPRL 274
+ FI AG T+S +++ ++ L ++P++Q K+ +EI +V + D + ++
Sbjct: 297 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL--QM 354
Query: 275 VYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHT 334
Y + V+ ETLRL+PIA + R + ++++ IP ++ Y L+R P + +
Sbjct: 355 EYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEK 414
Query: 335 FRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F PER+ + DP + F G RNCI
Sbjct: 415 FLPERFSKKNKDNIDPYIYTPFGSGPRNCI 444
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 93.9 bits (223), Expect = 8e-19
Identities = 81/367 (22%), Positives = 161/367 (43%), Gaps = 15/367 (4%)
Query: 6 ITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQMLN 62
ITDP+ TV E + + VG + + + E WKR R LL+P F+ L
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLK 143
Query: 63 IYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQK-Y 120
+ + L+ + + ++G PV + F ++ + ST+FG+ + + Q +
Sbjct: 144 EMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPF 203
Query: 121 MHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRALK 178
+ +L+ L +L L+ + + + + +++ K++ +
Sbjct: 204 VENTKKLLRF--NPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRL 261
Query: 179 NKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVV 238
+ + H + +A +D E+ + FI AG T+S +++ ++
Sbjct: 262 KETQKHR---VDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFII 318
Query: 239 MVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
L ++P++Q KV +EI +V + + D + +L Y + V+ ETLRL+P+A + R
Sbjct: 319 YELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--QLEYLDMVVNETLRLFPVAMRLERV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ ++++ IP ++ Y L+ P + + F PER+ + DP + F
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 SGPRNCI 443
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 93.9 bits (223), Expect = 8e-19
Identities = 81/367 (22%), Positives = 161/367 (43%), Gaps = 15/367 (4%)
Query: 6 ITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQMLN 62
ITDP+ TV E + + VG + + + E WKR R LL+P F+ L
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLK 143
Query: 63 IYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQK-Y 120
+ + L+ + + ++G PV + F ++ + ST+FG+ + + Q +
Sbjct: 144 EMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPF 203
Query: 121 MHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRALK 178
+ +L+ L +L L+ + + + + +++ K++ +
Sbjct: 204 VENTKKLLRF--NPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRL 261
Query: 179 NKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVV 238
+ + H + +A +D E+ + FI AG T+S +++ ++
Sbjct: 262 KETQKHR---VDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFII 318
Query: 239 MVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
L ++P++Q KV +EI +V + + D + +L Y + V+ ETLRL+P+A + R
Sbjct: 319 YELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--QLEYLDMVVNETLRLFPVAMRLERV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ ++++ IP ++ Y L+ P + + F PER+ + DP + F
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 SGPRNCI 443
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 93.9 bits (223), Expect = 8e-19
Identities = 81/367 (22%), Positives = 161/367 (43%), Gaps = 15/367 (4%)
Query: 6 ITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQMLN 62
ITDP+ TV E + + VG + + + E WKR R LL+P F+ L
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLK 143
Query: 63 IYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQK-Y 120
+ + L+ + + ++G PV + F ++ + ST+FG+ + + Q +
Sbjct: 144 EMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPF 203
Query: 121 MHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRALK 178
+ +L+ L +L L+ + + + + +++ K++ +
Sbjct: 204 VENTKKLLRF--NPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRL 261
Query: 179 NKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVV 238
+ + H + +A +D E+ + FI AG T+S +++ ++
Sbjct: 262 KETQKHR---VDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFII 318
Query: 239 MVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
L ++P++Q KV +EI +V + + D + +L Y + V+ ETLRL+P+A + R
Sbjct: 319 YELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--QLEYLDMVVNETLRLFPVAMRLERV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ ++++ IP ++ Y L+ P + + F PER+ + DP + F
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 SGPRNCI 443
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 93.9 bits (223), Expect = 8e-19
Identities = 81/367 (22%), Positives = 161/367 (43%), Gaps = 15/367 (4%)
Query: 6 ITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQMLN 62
ITDP+ TV E + + VG + + + E WKR R LL+P F+ L
Sbjct: 84 ITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKNAISIAEDEEWKRIRSLLSPTFTSGKLK 143
Query: 63 IYTAVFNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQK-Y 120
+ + L+ + + ++G PV + F ++ + ST+FG+ + + Q +
Sbjct: 144 EMVPIIAQYGDVLVRNLRREAETGKPVTLKHVFGAYSMDVITSTSFGVSIDSLNNPQDPF 203
Query: 121 MHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRALK 178
+ +L+ L +L L+ + + + + +++ K++ +
Sbjct: 204 VENTKKLLRF--NPLDPFVLSIKVFPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRL 261
Query: 179 NKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVV 238
+ + H + +A +D E+ + FI AG T+S +++ ++
Sbjct: 262 KETQKHR---VDFLQLMIDSQNSKDSETHKALSDLELMAQSIIFIFAGYETTSSVLSFII 318
Query: 239 MVLGSYPEIQDKVYQEIKSVCGD-SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
L ++P++Q KV +EI +V + + D + +L Y + V+ ETLRL+P+A + R
Sbjct: 319 YELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL--QLEYLDMVVNETLRLFPVAMRLERV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ ++++ IP ++ Y L+ P + + F PER+ + DP + F
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 SGPRNCI 443
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ40054 fis, clone TBAES2000315, weakly similar to
CYTOCHROME P450 4A1 (EC 1.14.15.3). ).
Length = 340
Score = 90.2 bits (214), Expect = 1e-17
Identities = 53/228 (23%), Positives = 110/228 (48%), Gaps = 5/228 (2%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + ++ R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAQ 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXX 202
++K S+ + + + + + K I ++ +LK+K + ++ ++
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDKLK--QDTTQKRRQDFLDILLSA 291
Query: 203 XXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDK 250
+ F++ +++ EV TF+ AG T++ ++ + L YPE Q +
Sbjct: 292 KSENTKDFSEADLQAEVKTFMFAGHDTTTTAISWIFYCLAKYPEHQQR 339
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 90.2 bits (214), Expect = 1e-17
Identities = 90/344 (26%), Positives = 146/344 (42%), Gaps = 27/344 (7%)
Query: 36 GLVTSAGETWKRHRKLLNPAFSQ-QMLNIYTAVFNRESRNLISAIEIQMKSG---PVLI- 90
GL+T+ GE W+R R LL P + Q Y N +L+ + Q G P L+
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 91 --TAAFKEMALKTLLSTAFG-----IEEEECDFNQKYMHAVDELMA--VLTRRLQNILLH 141
F + L+ + + G +E + + ++ AV + +LT + + L H
Sbjct: 185 DVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAVGSVFVSTLLTMAMPHWLRH 244
Query: 142 NSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXX 201
L + D++ A + + + +R A + + NG EK +
Sbjct: 245 -LVPGPWGRLCRDWDQMF----AFAQRHVE-RREA----EAAMRNGGQPEKDLESGAHLT 294
Query: 202 XXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD 261
E + I V + AG T S ++ + L +PE+Q ++ EI +
Sbjct: 295 HFLFREE-LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSP 353
Query: 262 -SDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIY 320
S A +L +AV+KE LRLYP+ P R + +I + +Y IP N+ L Y
Sbjct: 354 GSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHY 413
Query: 321 GLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+R P P+ ++FRP RWL G P P A F GKR+C+
Sbjct: 414 ATSRDPAQFPEPNSFRPARWLGEGPTP-HPFASLPFGFGKRSCM 456
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 84.6 bits (200), Expect = 5e-16
Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 2/158 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
+A T +EI V + AG T+S ++ V +L +PE+Q VY+EI G+
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPT- 221
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
P++ A+LKETLRL+P+ P R T+ ++ + Y IP + L Y +
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281
Query: 328 WGPDAHTFRPERWLEPGGVPDDPN-AFAGFSVGKRNCI 364
P A FRPERWL G + N F G R+CI
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCI 319
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 84.2 bits (199), Expect = 7e-16
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLANK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 83.8 bits (198), Expect = 9e-16
Identities = 53/158 (33%), Positives = 77/158 (48%), Gaps = 2/158 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
+A T +EI V + AG T+S ++ V +L +PE+Q VY+EI G+
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPT- 221
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
P++ A+LKETLRL+P+ P R T+ ++ + Y IP + L Y +
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281
Query: 328 WGPDAHTFRPERWLEPGGVPDDPN-AFAGFSVGKRNCI 364
P A FRPERWL G + N F G R+CI
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCI 319
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 83.4 bits (197), Expect = 1e-15
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 83.4 bits (197), Expect = 1e-15
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 83.4 bits (197), Expect = 1e-15
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 83.4 bits (197), Expect = 1e-15
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 83.4 bits (197), Expect = 1e-15
Identities = 84/367 (22%), Positives = 154/367 (41%), Gaps = 13/367 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFS 357
+ +I++ IP ++ IY L+ P + + F PER+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFG 436
Query: 358 VGKRNCI 364
G RNCI
Sbjct: 437 AGPRNCI 443
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 81.0 bits (191), Expect = 6e-15
Identities = 46/158 (29%), Positives = 80/158 (50%), Gaps = 6/158 (3%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADV--D 267
F+ + + V I AG+ T++ ++ ++ + YP IQ +V +EI + G + D
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDD 354
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
K + P YTEAVL E LR I P+ + T + ++ Y+IP + + +Y ++
Sbjct: 355 KCKMP---YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDE 411
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ D F PER+L+ G A FS+G+R+C+
Sbjct: 412 KYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCL 449
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 81.0 bits (191), Expect = 6e-15
Identities = 46/158 (29%), Positives = 80/158 (50%), Gaps = 6/158 (3%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADV--D 267
F+ + + V I AG+ T++ ++ ++ + YP IQ +V +EI + G + D
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDD 354
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
K + P YTEAVL E LR I P+ + T + ++ Y+IP + + +Y ++
Sbjct: 355 KCKMP---YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDE 411
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ D F PER+L+ G A FS+G+R+C+
Sbjct: 412 KYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCL 449
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 81.0 bits (191), Expect = 6e-15
Identities = 46/158 (29%), Positives = 80/158 (50%), Gaps = 6/158 (3%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADV--D 267
F+ + + V I AG+ T++ ++ ++ + YP IQ +V +EI + G + D
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDD 354
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
K + P YTEAVL E LR I P+ + T + ++ Y+IP + + +Y ++
Sbjct: 355 KCKMP---YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDE 411
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ D F PER+L+ G A FS+G+R+C+
Sbjct: 412 KYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCL 449
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 80.6 bits (190), Expect = 8e-15
Identities = 46/158 (29%), Positives = 85/158 (53%), Gaps = 3/158 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD-SDADV 266
+A +D E+ + FI AG T+S +++ ++ L ++P++Q K+ +EI +V + +
Sbjct: 138 KALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTY 197
Query: 267 DKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
D + ++ Y + V+ ETLRL+PIA + R + ++++ IP ++ Y L+R P
Sbjct: 198 DTVL--QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDP 255
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ + F PER+ + DP + F G RNCI
Sbjct: 256 KYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCI 293
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 79.0 bits (186), Expect = 3e-14
Identities = 84/368 (22%), Positives = 154/368 (41%), Gaps = 14/368 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPE-RWLEPGGVPDDPNAFAGF 356
+ +I++ IP ++ IY L+ P + + F PE R+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPF 436
Query: 357 SVGKRNCI 364
G RNCI
Sbjct: 437 GAGPRNCI 444
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 79.0 bits (186), Expect = 3e-14
Identities = 84/368 (22%), Positives = 154/368 (41%), Gaps = 14/368 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPE-RWLEPGGVPDDPNAFAGF 356
+ +I++ IP ++ IY L+ P + + F PE R+ + D + F
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPF 436
Query: 357 SVGKRNCI 364
G RNCI
Sbjct: 437 GAGPRNCI 444
>AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P450
protein.
Length = 295
Score = 77.8 bits (183), Expect = 6e-14
Identities = 46/158 (29%), Positives = 76/158 (48%), Gaps = 2/158 (1%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
Y F W+G GL+ G W +HRKLL P F +L Y AVF +R ++ E + +
Sbjct: 115 YDFFLQWIGRGLLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKARE 174
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEEECDF-NQKYMHAVDELMAVLTRRLQNILLHNS 143
G I MAL TL+ FG + + Y AV +L ++ +RL + HN
Sbjct: 175 GKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHRDSSYYLAVSDLTLLMQQRLVSFQYHND 234
Query: 144 FIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQ 181
FIY L+ ++ + +++ I ++ AL++++
Sbjct: 235 FIYWLTPHGRRFLRACQVAHDHTDQVIRERKAALQDEK 272
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 74.5 bits (175), Expect = 5e-13
Identities = 44/144 (30%), Positives = 74/144 (51%), Gaps = 4/144 (2%)
Query: 221 TFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAV 280
TF+ G T++ ++ ++ L ++P+ Q++ +EI + GD A + ++ YT
Sbjct: 1 TFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMC 59
Query: 281 LKETLRLYPIAPVVLRKTENEIKLKN-YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPER 339
+KE LRLYP P + R+ + + ++P +L IYGL+ +P P+ F P R
Sbjct: 60 IKEALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSR 119
Query: 340 WLEPGGVPDDPNAFAGFSVGKRNC 363
+ PG +AF FS G RNC
Sbjct: 120 F-APGSA-QHSHAFLPFSGGSRNC 141
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 74.5 bits (175), Expect = 5e-13
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
Query: 220 DTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDAD--VDKLQHPRLVYT 277
D FIA G+ T++ + ++ + P++Q+KV++EI+ V G + A DK Q P YT
Sbjct: 348 DLFIA-GTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMP---YT 403
Query: 278 EAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFR 336
EA + E RL + P+ + T L+ YTIP + L ++ ++R P F
Sbjct: 404 EATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFY 463
Query: 337 PERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P R+L+ G F F +GKR C+
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCM 491
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 74.5 bits (175), Expect = 5e-13
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 7/148 (4%)
Query: 220 DTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDAD--VDKLQHPRLVYT 277
D FIA G+ T++ + ++ + P++Q+KV++EI+ V G + A DK Q P YT
Sbjct: 348 DLFIA-GTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMP---YT 403
Query: 278 EAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFR 336
EA + E RL + P+ + T L+ YTIP + L ++ ++R P F
Sbjct: 404 EATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFY 463
Query: 337 PERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P R+L+ G F F +GKR C+
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCM 491
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 73.7 bits (173), Expect = 1e-12
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
+E + + AG T+S +T + L PEIQ+ +++E+ V K
Sbjct: 322 REAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHK-DFA 380
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +AVLKETLRLYP+ P R E EI++ + P N+ + Y ++R P +
Sbjct: 381 HMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEP 440
Query: 333 HTFRPERWLEPG--GVPDDPNAFAG--FSVGKRNCI 364
+F+P RWL P + F F G R C+
Sbjct: 441 ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACL 476
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 73.7 bits (173), Expect = 1e-12
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
+E + + AG T+S +T + L PEIQ+ +++E+ V K
Sbjct: 323 REAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHK-DFA 381
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +AVLKETLRLYP+ P R E EI++ + P N+ + Y ++R P +
Sbjct: 382 HMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEP 441
Query: 333 HTFRPERWLEPG--GVPDDPNAFAG--FSVGKRNCI 364
+F+P RWL P + F F G R C+
Sbjct: 442 ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACL 477
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 73.7 bits (173), Expect = 1e-12
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
+E + + AG T+S +T + L PEIQ+ +++E+ V K
Sbjct: 323 REAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHK-DFA 381
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +AVLKETLRLYP+ P R E EI++ + P N+ + Y ++R P +
Sbjct: 382 HMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEP 441
Query: 333 HTFRPERWLEPG--GVPDDPNAFAG--FSVGKRNCI 364
+F+P RWL P + F F G R C+
Sbjct: 442 ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACL 477
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 73.7 bits (173), Expect = 1e-12
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
+E + + AG T+S +T + L PEIQ+ +++E+ V K
Sbjct: 323 REAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHK-DFA 381
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +AVLKETLRLYP+ P R E EI++ + P N+ + Y ++R P +
Sbjct: 382 HMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEP 441
Query: 333 HTFRPERWLEPG--GVPDDPNAFAG--FSVGKRNCI 364
+F+P RWL P + F F G R C+
Sbjct: 442 ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACL 477
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 73.3 bits (172), Expect = 1e-12
Identities = 44/157 (28%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
+A +D E+ + I A T+S + ++ L ++P++Q K+ +EI +V + A V
Sbjct: 178 KALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK-APVT 236
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
++ Y + V+ ETLRL+P+ V R + +I++ IP ++ IY L+ P
Sbjct: 237 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPK 296
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ + F PER+ + D + F G RNCI
Sbjct: 297 YWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCI 333
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 73.3 bits (172), Expect = 1e-12
Identities = 77/342 (22%), Positives = 144/342 (42%), Gaps = 13/342 (3%)
Query: 5 VITDPEDNLTVANGELQKHYFYQFTSNWVG---DGLVTSAGETWKRHRKLLNPAFSQQML 61
VI DP+ TV E + Q +G L + E WKR R LL+PAF+
Sbjct: 83 VIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKF 142
Query: 62 NIYTAVFNRESRNLISAIEIQMK-SGPVLITAAFKEMALKTLLSTAFGIEEEECDFNQK- 119
+ ++ L+ ++ + + S + + F + + T FG+ + + Q
Sbjct: 143 KEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDP 202
Query: 120 YMHAVDELMAVLTRRLQNILLHNSFIYKLSALKKKEDELI--ETIMAMSNKAINSKRRAL 177
++ + +L+ L +LL + F + + L + + N K L
Sbjct: 203 FLKNMKKLLK-LDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRL 261
Query: 178 KNKQESHENGCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVV 237
K+KQ+ + +Q +A +D E+ + I A T+S + +
Sbjct: 262 KDKQKHRVDFFQQMIDSQNSKETKSH----KALSDLELVAQSIIIIFAAYDTTSTTLPFI 317
Query: 238 VMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRK 297
+ L ++P++Q K+ +EI +V + A V ++ Y + V+ ETLRL+P+ V R
Sbjct: 318 MYELATHPDVQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRV 376
Query: 298 TENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPER 339
+ +I++ IP ++ IY L+ P + + F PER
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 418
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 72.9 bits (171), Expect = 2e-12
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 16/336 (4%)
Query: 35 DGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAV--FNRESRNLISAIEIQMKSGPVLITA 92
+GL+ S+G+ WK R+ A L + E+++L AI+ + P
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIK-EENGQPFDPHF 182
Query: 93 AFKEMALKTLLSTAFGIEEEECD-FNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSAL 151
+ S FG E D + Q+ + +DE+ + + L+N F + + L
Sbjct: 183 KINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASK--TCQLYNVFPWIMKFL 240
Query: 152 KKKEDELIETI--MAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXEA 209
L + + + K R N E+ + A K+ E
Sbjct: 241 PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN 300
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
I + +D F A G+ T+S + ++ + YPEIQ+KV EI V G
Sbjct: 301 L----ICSTLDLFFA-GTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTA 354
Query: 270 QHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT AV+ E R+ I P+ V R+ + L Y +P + L + L+R P
Sbjct: 355 ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTE 414
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
TF P+ +LE G AF FS+GKR C+
Sbjct: 415 WATPDTFNPDHFLENGQF-KKREAFMPFSIGKRACL 449
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 72.9 bits (171), Expect = 2e-12
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 16/336 (4%)
Query: 35 DGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAV--FNRESRNLISAIEIQMKSGPVLITA 92
+GL+ S+G+ WK R+ A L + E+++L AI+ + P
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIK-EENGQPFDPHF 182
Query: 93 AFKEMALKTLLSTAFGIEEEECD-FNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSAL 151
+ S FG E D + Q+ + +DE+ + + L+N F + + L
Sbjct: 183 KINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASK--TCQLYNVFPWIMKFL 240
Query: 152 KKKEDELIETI--MAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXEA 209
L + + + K R N E+ + A K+ E
Sbjct: 241 PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN 300
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
I + +D F A G+ T+S + ++ + YPEIQ+KV EI V G
Sbjct: 301 L----ICSTLDLFFA-GTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTA 354
Query: 270 QHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT AV+ E R+ I P+ V R+ + L Y +P + L + L+R P
Sbjct: 355 ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTE 414
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
TF P+ +LE G AF FS+GKR C+
Sbjct: 415 WATPDTFNPDHFLENGQF-KKREAFMPFSIGKRACL 449
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 72.9 bits (171), Expect = 2e-12
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 16/336 (4%)
Query: 35 DGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAV--FNRESRNLISAIEIQMKSGPVLITA 92
+GL+ S+G+ WK R+ A L + E+++L AI+ + P
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIK-EENGQPFDPHF 182
Query: 93 AFKEMALKTLLSTAFGIEEEECD-FNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSAL 151
+ S FG E D + Q+ + +DE+ + + L+N F + + L
Sbjct: 183 KINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASK--TCQLYNVFPWIMKFL 240
Query: 152 KKKEDELIETI--MAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXEA 209
L + + + K R N E+ + A K+ E
Sbjct: 241 PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN 300
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
I + +D F A G+ T+S + ++ + YPEIQ+KV EI V G
Sbjct: 301 L----ICSTLDLFFA-GTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTA 354
Query: 270 QHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT AV+ E R+ I P+ V R+ + L Y +P + L + L+R P
Sbjct: 355 ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTE 414
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
TF P+ +LE G AF FS+GKR C+
Sbjct: 415 WATPDTFNPDHFLENGQF-KKREAFMPFSIGKRACL 449
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 72.9 bits (171), Expect = 2e-12
Identities = 46/156 (29%), Positives = 71/156 (45%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
+E + + AG T+S +T + L PEIQ +++E+ V K
Sbjct: 323 REAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHK-DFA 381
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +AVLKETLRLYP+ P R E EI++ + P N+ + Y ++R P +
Sbjct: 382 HMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFSEP 441
Query: 333 HTFRPERWLEPG--GVPDDPNAFAG--FSVGKRNCI 364
+F+P RWL P + F F G R C+
Sbjct: 442 ESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACL 477
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 72.9 bits (171), Expect = 2e-12
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 16/336 (4%)
Query: 35 DGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAV--FNRESRNLISAIEIQMKSGPVLITA 92
+GL+ S+G+ WK R+ A L + E+++L AI+ + P
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIK-EENGQPFDPHF 182
Query: 93 AFKEMALKTLLSTAFGIEEEECD-FNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSAL 151
+ S FG E D + Q+ + +DE+ + + L+N F + + L
Sbjct: 183 KINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASK--TCQLYNVFPWIMKFL 240
Query: 152 KKKEDELIETI--MAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXEA 209
L + + + K R N E+ + A K+ E
Sbjct: 241 PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN 300
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
I + +D F A G+ T+S + ++ + YPEIQ+KV EI V G
Sbjct: 301 L----ICSTLDLFFA-GTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTA 354
Query: 270 QHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT AV+ E R+ I P+ V R+ + L Y +P + L + L+R P
Sbjct: 355 ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTE 414
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
TF P+ +LE G AF FS+GKR C+
Sbjct: 415 WATPDTFNPDHFLENGQF-KKREAFMPFSIGKRACL 449
>AY696295-1|AAU10524.1| 292|Homo sapiens cytochrome P450 protein.
Length = 292
Score = 72.5 bits (170), Expect = 2e-12
Identities = 40/158 (25%), Positives = 79/158 (50%), Gaps = 3/158 (1%)
Query: 26 YQFTSNWVGDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKS 85
++ +WVG GLVT G WK+HR+++ P F+ +L I+ + ++ R +++ E +
Sbjct: 114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSKSVRMMLNKWEEHIAH 173
Query: 86 GPVL-ITAAFKEMALKTLLSTAFGIEEE-ECDFN-QKYMHAVDELMAVLTRRLQNILLHN 142
L + M L +++ AF + + D Y+ AV L + +R+ N L HN
Sbjct: 174 NSRLELFQHVSLMTLHSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHN 233
Query: 143 SFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNK 180
++K S+ + + + + + K I ++ +LK+K
Sbjct: 234 DLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKDK 271
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 72.5 bits (170), Expect = 2e-12
Identities = 83/336 (24%), Positives = 134/336 (39%), Gaps = 16/336 (4%)
Query: 35 DGLVTSAGETWKRHRKLLNPAFSQQMLNIYTAV--FNRESRNLISAIEIQMKSGPVLITA 92
+GL+ S+G+ WK R+ A L + E+++L AI+ + P
Sbjct: 124 NGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIK-EENGQPFDPHF 182
Query: 93 AFKEMALKTLLSTAFGIEEEECD-FNQKYMHAVDELMAVLTRRLQNILLHNSFIYKLSAL 151
+ S FG E D + Q+ + +DE+ + + L+N F + + L
Sbjct: 183 KINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASK--TCQLYNVFPWIMKFL 240
Query: 152 KKKEDELIETI--MAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXEA 209
L + + + K R N E+ + A K+ E
Sbjct: 241 PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN 300
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
I + +D F A G+ T+S + ++ + YPEIQ+KV EI V G
Sbjct: 301 L----ICSTLDLFFA-GTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQ-QPSTA 354
Query: 270 QHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT AV+ E R+ I P+ V R+ + L Y +P + L + L+R P
Sbjct: 355 ARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTE 414
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
TF P+ +LE G AF FS+GKR C+
Sbjct: 415 WATPDTFNPDHFLENGQF-KKREAFMPFSIGKRACL 449
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 269 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 327
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 328 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 387
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 388 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 423
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 175 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 233
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 234 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 293
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 294 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 329
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 279 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 337
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 338 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 397
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 398 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 433
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 436
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 436
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 436
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 72.1 bits (169), Expect = 3e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG F FS GKR C+
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICV 436
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 70.9 bits (166), Expect = 7e-12
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 162 FTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 220
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 221 DRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 280
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 281 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 316
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 69.3 bits (162), Expect = 2e-11
Identities = 44/156 (28%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 148 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 206
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L + +
Sbjct: 207 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKE 266
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 267 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 302
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 69.3 bits (162), Expect = 2e-11
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 335
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G F FS GKR C+
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICV 431
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 69.3 bits (162), Expect = 2e-11
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + N AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 335
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L +IK +NY IP + L+ + +
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G F FS GKR C+
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICV 431
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 341 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 401 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 436
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 9 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQ- 67
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 68 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 127
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 128 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 163
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 260 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 318
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 319 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 378
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 379 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 414
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 341 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 401 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 436
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 341 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 401 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 436
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.9 bits (161), Expect = 3e-11
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + + AG+ T+S + +++L +PE+ KV +EI+ V G + + +
Sbjct: 282 FTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K +NY IP + L + +
Sbjct: 341 DRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ GG N F FS GKR C+
Sbjct: 401 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 436
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 68.5 bits (160), Expect = 4e-11
Identities = 80/344 (23%), Positives = 144/344 (41%), Gaps = 32/344 (9%)
Query: 33 VGDGLVTSAGET-WKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGP--VL 89
+G G +++ ++ K+ +K++ AFS++ L Y V E + S++E + G +L
Sbjct: 51 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEE---VGSSLEQWLSCGERGLL 107
Query: 90 ITAAFKEMALKTLLSTAFGIEEE---ECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIY 146
+ K + + + G E + + D Q+ + A +E+ TR L ++ + F
Sbjct: 108 VYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEM----TRNLFSLPIDVPFSG 163
Query: 147 KLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXX 206
+K + I A + I +K L+ + GC K
Sbjct: 164 LYRGMKARN-----LIHARIEQNIRAKICGLRASEAGQ--GC----KDALQLLIEHSWER 212
Query: 207 XEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKS---VC-GDS 262
E + ++ + G T++ T ++ LG YP + KV +E+KS +C +
Sbjct: 213 GERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQ 272
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGL 322
D +D +L Y V+KETLRL P P R +L Y IP N + I
Sbjct: 273 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 332
Query: 323 NRHPVWGPDAHTFRPERWLEPGGVPDDPN--AFAGFSVGKRNCI 364
+ + F P+R++ P P+D + +F F G R+C+
Sbjct: 333 HDVAEIFTNKEEFNPDRFMLPH--PEDASRFSFIPFGGGLRSCV 374
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 68.5 bits (160), Expect = 4e-11
Identities = 80/344 (23%), Positives = 144/344 (41%), Gaps = 32/344 (9%)
Query: 33 VGDGLVTSAGET-WKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGP--VL 89
+G G +++ ++ K+ +K++ AFS++ L Y V E + S++E + G +L
Sbjct: 120 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEE---VGSSLEQWLSCGERGLL 176
Query: 90 ITAAFKEMALKTLLSTAFGIEEE---ECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIY 146
+ K + + + G E + + D Q+ + A +E+ TR L ++ + F
Sbjct: 177 VYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEM----TRNLFSLPIDVPFSG 232
Query: 147 KLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXX 206
+K + I A + I +K L+ + GC K
Sbjct: 233 LYRGMKARN-----LIHARIEQNIRAKICGLRASEAGQ--GC----KDALQLLIEHSWER 281
Query: 207 XEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKS---VC-GDS 262
E + ++ + G T++ T ++ LG YP + KV +E+KS +C +
Sbjct: 282 GERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQ 341
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGL 322
D +D +L Y V+KETLRL P P R +L Y IP N + I
Sbjct: 342 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 323 NRHPVWGPDAHTFRPERWLEPGGVPDDPN--AFAGFSVGKRNCI 364
+ + F P+R++ P P+D + +F F G R+C+
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPH--PEDASRFSFIPFGGGLRSCV 443
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 68.5 bits (160), Expect = 4e-11
Identities = 80/344 (23%), Positives = 144/344 (41%), Gaps = 32/344 (9%)
Query: 33 VGDGLVTSAGET-WKRHRKLLNPAFSQQMLNIYTAVFNRESRNLISAIEIQMKSGP--VL 89
+G G +++ ++ K+ +K++ AFS++ L Y V E + S++E + G +L
Sbjct: 120 LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEE---VGSSLEQWLSCGERGLL 176
Query: 90 ITAAFKEMALKTLLSTAFGIEEE---ECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIY 146
+ K + + + G E + + D Q+ + A +E+ TR L ++ + F
Sbjct: 177 VYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEM----TRNLFSLPIDVPFSG 232
Query: 147 KLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXX 206
+K + I A + I +K L+ + GC K
Sbjct: 233 LYRGMKARN-----LIHARIEQNIRAKICGLRASEAGQ--GC----KDALQLLIEHSWER 281
Query: 207 XEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKS---VC-GDS 262
E + ++ + G T++ T ++ LG YP + KV +E+KS +C +
Sbjct: 282 GERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQ 341
Query: 263 DADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGL 322
D +D +L Y V+KETLRL P P R +L Y IP N + I
Sbjct: 342 DNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 323 NRHPVWGPDAHTFRPERWLEPGGVPDDPN--AFAGFSVGKRNCI 364
+ + F P+R++ P P+D + +F F G R+C+
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPH--PEDASRFSFIPFGGGLRSCV 443
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 67.3 bits (157), Expect = 8e-11
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
KE+ V A T++ + ++ L P++Q K+ +EI+SV ++ V + +
Sbjct: 57 KELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQ--VPRAEDL 114
Query: 273 R-LVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPD 331
R + Y +A LKE++RL P P R + L Y +P + +L L D
Sbjct: 115 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFED 174
Query: 332 AHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ FRPERWL+ +P A F VGKR CI
Sbjct: 175 SSQFRPERWLQE-KEKINPFAHLPFGVGKRMCI 206
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 292 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 411 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 447
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 165 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 223
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 224 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 283
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 284 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 320
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 288 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 346
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 347 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 406
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 407 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 443
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 67.3 bits (157), Expect = 8e-11
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
KE+ V A T++ + ++ L P++Q K+ +EI+SV ++ V + +
Sbjct: 172 KELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQ--VPRAEDL 229
Query: 273 R-LVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPD 331
R + Y +A LKE++RL P P R + L Y +P + +L L D
Sbjct: 230 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFED 289
Query: 332 AHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ FRPERWL+ +P A F VGKR CI
Sbjct: 290 SSQFRPERWLQE-KEKINPFAHLPFGVGKRMCI 321
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 67.3 bits (157), Expect = 8e-11
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
KE+ V A T++ + ++ L P++Q K+ +EI+SV ++ V + +
Sbjct: 314 KELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQ--VPRAEDL 371
Query: 273 R-LVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPD 331
R + Y +A LKE++RL P P R + L Y +P + +L L D
Sbjct: 372 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFED 431
Query: 332 AHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ FRPERWL+ +P A F VGKR CI
Sbjct: 432 SSQFRPERWLQE-KEKINPFAHLPFGVGKRMCI 463
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 67.3 bits (157), Expect = 8e-11
Identities = 47/153 (30%), Positives = 73/153 (47%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
KE+ V A T++ + ++ L P++Q K+ +EI+SV ++ V + +
Sbjct: 172 KELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQ--VPRAEDL 229
Query: 273 R-LVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPD 331
R + Y +A LKE++RL P P R + L Y +P + +L L D
Sbjct: 230 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFED 289
Query: 332 AHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ FRPERWL+ +P A F VGKR CI
Sbjct: 290 SSQFRPERWLQE-KEKINPFAHLPFGVGKRMCI 321
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 67.3 bits (157), Expect = 8e-11
Identities = 45/158 (28%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 358 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 416
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 417 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 476
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 477 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 513
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 102 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 160
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 161 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 220
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 221 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 256
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 223 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 281
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 282 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 341
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 342 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 377
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 66.9 bits (156), Expect = 1e-10
Identities = 43/156 (27%), Positives = 73/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/337 (22%), Positives = 132/337 (39%), Gaps = 14/337 (4%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA--VFNRESRNLISAI---EIQMKSGPV 88
G G+ S GE W++ RK A + + E+R L+ E + +
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 89 LITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKL 148
L+ A + L F E++E F A L+ V ++ Q + + F+ L
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDKE--FQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPL 230
Query: 149 SALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE 208
K+ + T+ A + + + + L + + A K
Sbjct: 231 PGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTE---- 286
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
FT+K + V + AG+ T S + +++L YP +Q V +E+ G A
Sbjct: 287 -FTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAP-SL 344
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKT-ENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
RL YT+AVL E RL + P+ + +T + + YT+P + + + P
Sbjct: 345 GDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPN 404
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F P+R+L+ G AF FS+GKR C+
Sbjct: 405 IFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCL 441
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/337 (22%), Positives = 132/337 (39%), Gaps = 14/337 (4%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA--VFNRESRNLISAI---EIQMKSGPV 88
G G+ S GE W++ RK A + + E+R L+ E + +
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 89 LITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKL 148
L+ A + L F E++E F A L+ V ++ Q + + F+ L
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDKE--FQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPL 230
Query: 149 SALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE 208
K+ + T+ A + + + + L + + A K
Sbjct: 231 PGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTE---- 286
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
FT+K + V + AG+ T S + +++L YP +Q V +E+ G A
Sbjct: 287 -FTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAP-SL 344
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKT-ENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
RL YT+AVL E RL + P+ + +T + + YT+P + + + P
Sbjct: 345 GDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPN 404
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F P+R+L+ G AF FS+GKR C+
Sbjct: 405 IFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCL 441
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/298 (25%), Positives = 118/298 (39%), Gaps = 27/298 (9%)
Query: 68 FNRESRNLISAIEIQMKSG-PVLITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDE 126
FN ++ L+ +E + PV + A+ L AFG+E QK + +
Sbjct: 4 FNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQKPLSQAVK 63
Query: 127 LMAVLTRRLQNILLHNSFIYKLSALKKKEDELIETIMAMSNKAINSKRRALKNKQESHEN 186
LM +N L F+ ++ E I + + + +R ALK +E +
Sbjct: 64 LMLEGITASRNTLA--KFLPGKRKQLREVRESIRFLRQVGRDWVQRRREALKRGEEVPAD 121
Query: 187 GCASEKKTQXXXXXXXXXXXXEAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPE 246
K + A D+ + + TF AG TS+ + VM L PE
Sbjct: 122 ILTQILKAEEG-----------AQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPE 170
Query: 247 IQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKN 306
I ++ E+ V G S +D RL Y VLKE+LRLYP A R E E +
Sbjct: 171 IVARLQAEVDEVIG-SKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG 229
Query: 307 YTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
++ Y + R + D TF P+R+ G P + FS+G R+CI
Sbjct: 230 FS----------TYVMGRMDTYFEDPLTFNPDRF--GPGAPKPRFTYFPFSLGHRSCI 275
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/337 (22%), Positives = 132/337 (39%), Gaps = 14/337 (4%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA--VFNRESRNLISAI---EIQMKSGPV 88
G G+ S GE W++ RK A + + E+R L+ E + +
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 89 LITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKL 148
L+ A + L F E++E F A L+ V ++ Q + + F+ L
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDKE--FQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPL 230
Query: 149 SALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE 208
K+ + T+ A + + + + L + + A K
Sbjct: 231 PGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTE---- 286
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
FT+K + V + AG+ T S + +++L YP +Q V +E+ G A
Sbjct: 287 -FTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAP-SL 344
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKT-ENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
RL YT+AVL E RL + P+ + +T + + YT+P + + + P
Sbjct: 345 GDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPN 404
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F P+R+L+ G AF FS+GKR C+
Sbjct: 405 IFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCL 441
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 66.5 bits (155), Expect = 1e-10
Identities = 77/337 (22%), Positives = 132/337 (39%), Gaps = 14/337 (4%)
Query: 34 GDGLVTSAGETWKRHRKLLNPAFSQQMLNIYTA--VFNRESRNLISAI---EIQMKSGPV 88
G G+ S GE W++ RK A + + E+R L+ E + +
Sbjct: 113 GHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSL 172
Query: 89 LITAAFKEMALKTLLSTAFGIEEEECDFNQKYMHAVDELMAVLTRRLQNILLHNSFIYKL 148
L+ A + L F E++E F A L+ V ++ Q + + F+ L
Sbjct: 173 LLAQATSNVVCSLLFGLRFSYEDKE--FQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPL 230
Query: 149 SALKKKEDELIETIMAMSNKAINSKRRALKNKQESHENGCASEKKTQXXXXXXXXXXXXE 208
K+ + T+ A + + + + L + + A K
Sbjct: 231 PGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTE---- 286
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
FT+K + V + AG+ T S + +++L YP +Q V +E+ G A
Sbjct: 287 -FTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAP-SL 344
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPVVLRKT-ENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
RL YT+AVL E RL + P+ + +T + + YT+P + + + P
Sbjct: 345 GDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPN 404
Query: 328 WGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
F P+R+L+ G AF FS+GKR C+
Sbjct: 405 IFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCL 441
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 239 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 297
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 298 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 356
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 357 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 393
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ + T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 66.1 bits (154), Expect = 2e-10
Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ +R V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ + T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 66.1 bits (154), Expect = 2e-10
Identities = 43/156 (27%), Positives = 72/156 (46%), Gaps = 2/156 (1%)
Query: 210 FTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKL 269
FT + + V AG+ T+S + +++L YPE+ KV +EI+ V G + + +
Sbjct: 282 FTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQ- 340
Query: 270 QHPRLVYTEAVLKETLRLYPIAPVVLRKTEN-EIKLKNYTIPANSNCLLGIYGLNRHPVW 328
+ YT+AV+ E R + P L ++K KNY IP + + + +
Sbjct: 341 DRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGMTIITSLTSVLHNDKE 400
Query: 329 GPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+ F P +L+ G + F FS GKR C+
Sbjct: 401 FPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCM 436
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 66.1 bits (154), Expect = 2e-10
Identities = 45/152 (29%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
KE+ V A T++ + ++ L P++Q K+ +EI+SV ++ ++
Sbjct: 313 KELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREE-DLR 371
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ Y +A LKE++RL P P R + L Y +P + +L L D+
Sbjct: 372 NMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDS 431
Query: 333 HTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
FRPERWL+ +P A F VGKR CI
Sbjct: 432 SQFRPERWLQE-KEKINPFAHLPFGVGKRMCI 462
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 66.1 bits (154), Expect = 2e-10
Identities = 41/157 (26%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 403 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 439
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/153 (28%), Positives = 75/153 (49%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
++I+ V +A G T+S + + + ++QD + E+ + + D+ +
Sbjct: 314 EDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQ- 372
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +A +KETLRL+PI+ + R N++ L++Y IPA + + IY L R P + D
Sbjct: 373 LVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDP 432
Query: 333 HTFRPERWL-EPGGVPDDPNAFAGFSVGKRNCI 364
F P RWL + + N GF G R C+
Sbjct: 433 ENFDPTRWLSKDKNITYFRN--LGFGWGVRQCL 463
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/153 (28%), Positives = 75/153 (49%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
++I+ V +A G T+S + + + ++QD + E+ + + D+ +
Sbjct: 32 EDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQ- 90
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +A +KETLRL+PI+ + R N++ L++Y IPA + + IY L R P + D
Sbjct: 91 LVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDP 150
Query: 333 HTFRPERWL-EPGGVPDDPNAFAGFSVGKRNCI 364
F P RWL + + N GF G R C+
Sbjct: 151 ENFDPTRWLSKDKNITYFRN--LGFGWGVRQCL 181
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/153 (28%), Positives = 75/153 (49%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
++I+ V +A G T+S + + + ++QD + E+ + + D+ +
Sbjct: 314 EDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQ- 372
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +A +KETLRL+PI+ + R N++ L++Y IPA + + IY L R P + D
Sbjct: 373 LVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDP 432
Query: 333 HTFRPERWL-EPGGVPDDPNAFAGFSVGKRNCI 364
F P RWL + + N GF G R C+
Sbjct: 433 ENFDPTRWLSKDKNITYFRN--LGFGWGVRQCL 463
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/153 (28%), Positives = 75/153 (49%), Gaps = 4/153 (2%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
++I+ V +A G T+S + + + ++QD + E+ + + D+ +
Sbjct: 314 EDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQ- 372
Query: 273 RLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDA 332
+ +A +KETLRL+PI+ + R N++ L++Y IPA + + IY L R P + D
Sbjct: 373 LVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDP 432
Query: 333 HTFRPERWL-EPGGVPDDPNAFAGFSVGKRNCI 364
F P RWL + + N GF G R C+
Sbjct: 433 ENFDPTRWLSKDKNITYFRN--LGFGWGVRQCL 463
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 65.3 bits (152), Expect = 3e-10
Identities = 41/157 (26%), Positives = 79/157 (50%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + + ++ FIA G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLMMSTLNLFIA-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L+ G +AF FS+GKR C
Sbjct: 403 SFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYC 439
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 65.3 bits (152), Expect = 3e-10
Identities = 41/157 (26%), Positives = 79/157 (50%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + + ++ FIA G+ T S + ++L +PE++ KV++EI V G +
Sbjct: 285 EFYLKNLMMSTLNLFIA-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKF 343
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 344 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDP 402
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L+ G +AF FS+GKR C
Sbjct: 403 SFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYC 439
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 65.3 bits (152), Expect = 3e-10
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 211 TDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQ 270
TD E+ + + AG HTSS + L +Q K Y E K+VCG++ + Q
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 271 HPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTI-PANSNCLLGIYGLNRHPVWG 329
L + +KETLRL P +++R + YTI P + C+ W
Sbjct: 363 LKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSW- 421
Query: 330 PDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ F P+R+L+ + A+ F G+ CI
Sbjct: 422 VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.3 bits (152), Expect = 3e-10
Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 4/160 (2%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E +D I + AG T++ ++ + L P+++ K+Y+EI G S
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
++ RL+ EA ++E LRL P+AP+++ K + + + + + ++ ++ L+ +
Sbjct: 345 SDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNE 403
Query: 327 VWGPDAHTFRPERWLEPGGVP-DDPN-AFAGFSVGKRNCI 364
F PER+L P G P+ ++ F G R+CI
Sbjct: 404 KEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCI 443
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 64.9 bits (151), Expect = 4e-10
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 211 TDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQ 270
TD E+ + + AG HTSS + L +Q K Y E K+VCG++ + Q
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 271 HPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTI-PANSNCLLGIYGLNRHPVWG 329
L + +KETLRL P +++R + YTI P + C+ W
Sbjct: 363 LKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSW- 421
Query: 330 PDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ F P+R+L+ + A+ F G+ CI
Sbjct: 422 VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 64.9 bits (151), Expect = 4e-10
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 211 TDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQ 270
TD E+ + + AG HTSS + L +Q K Y E K+VCG++ + Q
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 271 HPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTI-PANSNCLLGIYGLNRHPVWG 329
L + +KETLRL P +++R + YTI P + C+ W
Sbjct: 363 LKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSW- 421
Query: 330 PDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ F P+R+L+ + A+ F G+ CI
Sbjct: 422 VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 64.9 bits (151), Expect = 4e-10
Identities = 43/155 (27%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 211 TDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQ 270
TD E+ + + AG HTSS + L +Q K Y E K+VCG++ + Q
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 271 HPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTI-PANSNCLLGIYGLNRHPVWG 329
L + +KETLRL P +++R + YTI P + C+ W
Sbjct: 363 LKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSW- 421
Query: 330 PDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ F P+R+L+ + A+ F G+ CI
Sbjct: 422 VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 64.5 bits (150), Expect = 6e-10
Identities = 40/157 (25%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
E + + ++ FI G+ T S + ++L +PE++ +V++EI V G +
Sbjct: 280 EFYLKNLVMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNRQPKF 338
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHP 326
+ ++ Y EAV+ E R + P+ L R+ + + K +++ +P + + + R P
Sbjct: 339 E-DRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDP 397
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNC 363
+ + F P+ +L G +AF FS+GKRNC
Sbjct: 398 SFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNC 434
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 64.1 bits (149), Expect = 8e-10
Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 223 IAAGS-HTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVL 281
+ AGS T+ + + + L P +Q + QE + K L A L
Sbjct: 311 LTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKAT-TELPLLRAAL 369
Query: 282 KETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWL 341
KETLRLYP+ + R +++ L+NY IPA + + +Y L R+P P + P+RWL
Sbjct: 370 KETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 429
Query: 342 EPGGVPDDPNAF-AGFSVGKRNCI 364
+ G N + F G R C+
Sbjct: 430 DIRG--SGRNFYHVPFGFGMRQCL 451
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 64.1 bits (149), Expect = 8e-10
Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 223 IAAGS-HTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVL 281
+ AGS T+ + + + L P +Q + QE + K L A L
Sbjct: 311 LTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKAT-TELPLLRAAL 369
Query: 282 KETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWL 341
KETLRLYP+ + R +++ L+NY IPA + + +Y L R+P P + P+RWL
Sbjct: 370 KETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 429
Query: 342 EPGGVPDDPNAF-AGFSVGKRNCI 364
+ G N + F G R C+
Sbjct: 430 DIRG--SGRNFYHVPFGFGMRQCL 451
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 64.1 bits (149), Expect = 8e-10
Identities = 36/101 (35%), Positives = 54/101 (53%), Gaps = 8/101 (7%)
Query: 270 QHPRLVYTE-----AVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNR 324
+HP+ TE A LKETLRLYP+ ++ R +++ L+NY IPA + + +Y L R
Sbjct: 143 EHPQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYSLGR 202
Query: 325 HPVWGPDAHTFRPERWLEPGGVPDDPNAF-AGFSVGKRNCI 364
+P P + P+RWL+ G N + F G R C+
Sbjct: 203 NPALFPRPERYNPQRWLDIKG--SGRNFYHVPFGFGMRQCL 241
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 292 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 411 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 447
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 357 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 393
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 357 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 393
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 64.1 bits (149), Expect = 8e-10
Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 223 IAAGS-HTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVL 281
+ AGS T+ + + + L P +Q + QE + K L A L
Sbjct: 311 LTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKAT-TELPLLRAAL 369
Query: 282 KETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWL 341
KETLRLYP+ + R +++ L+NY IPA + + +Y L R+P P + P+RWL
Sbjct: 370 KETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 429
Query: 342 EPGGVPDDPNAF-AGFSVGKRNCI 364
+ G N + F G R C+
Sbjct: 430 DIRG--SGRNFYHVPFGFGMRQCL 451
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 64.1 bits (149), Expect = 8e-10
Identities = 43/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 223 IAAGS-HTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVL 281
+ AGS T+ + + + L P +Q + QE + K L A L
Sbjct: 382 LTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKAT-TELPLLRAAL 440
Query: 282 KETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWL 341
KETLRLYP+ + R +++ L+NY IPA + + +Y L R+P P + P+RWL
Sbjct: 441 KETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 500
Query: 342 EPGGVPDDPNAF-AGFSVGKRNCI 364
+ G N + F G R C+
Sbjct: 501 DIRG--SGRNFYHVPFGFGMRQCL 522
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 408 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 444
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 64.1 bits (149), Expect = 8e-10
Identities = 47/156 (30%), Positives = 71/156 (45%), Gaps = 5/156 (3%)
Query: 213 KEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHP 272
++I N V+ AG T + ++ +M L + PEIQ K+ +E+ +V G + P
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIG-RERRPRLSDRP 363
Query: 273 RLVYTEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPD 331
+L Y EA + ET R P P + T + L + IP + + +N P D
Sbjct: 364 QLPYLEAFILETFRHSPFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 332 AHTFRPERWLEPGGVP-DDP--NAFAGFSVGKRNCI 364
FRPER+L G + P F +GKR CI
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCI 459
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 64.1 bits (149), Expect = 8e-10
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 209 AFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDK 268
+F D+ + V +AG T+S + ++++ +P++Q +V QEI V G +
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 269 LQHPRLVYTEAVLKETLRLYPIAPV-VLRKTENEIKLKNYTIPANSNCLLGIYG-LNRHP 326
+ YT AV+ E R I P+ V T +I+++ + IP + + + L
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 327 VWGPDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
VW F PE +L+ G P AF FS G+R C+
Sbjct: 357 VW-EKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACL 393
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 64.1 bits (149), Expect = 8e-10
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 223 IAAGSHTSSQL-MTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVL 281
+ AGS ++ + + + L P +Q + QE + K L A L
Sbjct: 311 LTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKAT-TELPLLRAAL 369
Query: 282 KETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWL 341
KETLRLYP+ + R +++ L+NY IPA + + +Y L R+P P + P+RWL
Sbjct: 370 KETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWL 429
Query: 342 EPGGVPDDPNAF-AGFSVGKRNCI 364
+ G N + F G R C+
Sbjct: 430 DIRG--SGRNFYHVPFGFGMRQCL 451
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 63.7 bits (148), Expect = 1e-09
Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 2/155 (1%)
Query: 211 TDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQ 270
TD E+ + + AG HTSS + L +Q K Y E K+VCG++ + Q
Sbjct: 297 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 356
Query: 271 HPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTI-PANSNCLLGIYGLNRHPVWG 329
L + ++ETLRL P +++R + YTI P + C+ W
Sbjct: 357 LKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSW- 415
Query: 330 PDAHTFRPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
+ F P+R+L+ + A+ F G+ CI
Sbjct: 416 VERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 450
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 63.3 bits (147), Expect = 1e-09
Identities = 45/149 (30%), Positives = 70/149 (46%), Gaps = 8/149 (5%)
Query: 219 VDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGD--SDADVDKLQHPRLVY 276
VD I G+ T++ ++ V+ L +PEIQ ++ +E+ G S + V H RL
Sbjct: 287 VDLLIG-GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPL 345
Query: 277 TEAVLKETLRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTF 335
A + E LRL P+ P+ L +T + Y IP + + + G + H F
Sbjct: 346 LNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF 405
Query: 336 RPERWLEPGGVPDDPNAFAGFSVGKRNCI 364
P+R+LEPG + A A F G R C+
Sbjct: 406 WPDRFLEPG---KNSRALA-FGCGARVCL 430
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 63.3 bits (147), Expect = 1e-09
Identities = 37/132 (28%), Positives = 68/132 (51%), Gaps = 1/132 (0%)
Query: 208 EAFTDKEIRNEVDTFIAAGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVD 267
+A +D E+ + I A T+S + ++ L ++P++Q K+ +EI +V + A V
Sbjct: 148 KALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK-APVT 206
Query: 268 KLQHPRLVYTEAVLKETLRLYPIAPVVLRKTENEIKLKNYTIPANSNCLLGIYGLNRHPV 327
++ Y + V+ ETLRL+P+ V R + +I++ IP ++ IY L+ P
Sbjct: 207 YDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPK 266
Query: 328 WGPDAHTFRPER 339
+ + F PER
Sbjct: 267 YWTEPEKFCPER 278
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
Query: 225 AGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKET 284
AG+ T S + ++L +PE++ KV++EI V G + + ++ YTEAV+ E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFE-DRAKMPYTEAVIHEI 359
Query: 285 LRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEP 343
R + P+ L + + K +++ +P + + + R P + + F P+ +L+
Sbjct: 360 QRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDK 419
Query: 344 GGVPDDPNAFAGFSVGKRNC 363
G +AF FS+GKR C
Sbjct: 420 KGQFKKSDAFVPFSIGKRYC 439
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
Query: 225 AGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKET 284
AG+ T S + ++L +PE++ KV++EI V G + + ++ YTEAV+ E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFE-DRAKMPYTEAVIHEI 359
Query: 285 LRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEP 343
R + P+ L + + K +++ +P + + + R P + + F P+ +L+
Sbjct: 360 QRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDK 419
Query: 344 GGVPDDPNAFAGFSVGKRNC 363
G +AF FS+GKR C
Sbjct: 420 KGQFKKSDAFVPFSIGKRYC 439
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 63.3 bits (147), Expect = 1e-09
Identities = 38/140 (27%), Positives = 70/140 (50%), Gaps = 2/140 (1%)
Query: 225 AGSHTSSQLMTVVVMVLGSYPEIQDKVYQEIKSVCGDSDADVDKLQHPRLVYTEAVLKET 284
AG+ T S + ++L +PE++ KV++EI V G + + ++ YTEAV+ E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFE-DRAKMPYTEAVIHEI 359
Query: 285 LRLYPIAPVVL-RKTENEIKLKNYTIPANSNCLLGIYGLNRHPVWGPDAHTFRPERWLEP 343
R + P+ L + + K +++ +P + + + R P + + F P+ +L+
Sbjct: 360 QRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDK 419
Query: 344 GGVPDDPNAFAGFSVGKRNC 363
G +AF FS+GKR C
Sbjct: 420 KGQFKKSDAFVPFSIGKRYC 439
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.133 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 52,049,801
Number of Sequences: 224733
Number of extensions: 2079076
Number of successful extensions: 5267
Number of sequences better than 10.0: 435
Number of HSP's better than 10.0 without gapping: 311
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 4322
Number of HSP's gapped (non-prelim): 546
length of query: 377
length of database: 73,234,838
effective HSP length: 91
effective length of query: 286
effective length of database: 52,784,135
effective search space: 15096262610
effective search space used: 15096262610
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 66 (30.7 bits)
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