Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002251-TA|BGIBMGA002251-PA|IPR000091|Huntingtin
(1855 letters)
Database: fruitfly
52,641 sequences; 24,830,863 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF147779-1|AAF03256.1| 3583|Drosophila melanogaster Huntington d... 81 1e-14
AF146362-1|AAF03255.1| 3583|Drosophila melanogaster Huntington d... 81 1e-14
AE014297-4258|AAF56808.1| 3583|Drosophila melanogaster CG9995-PA... 81 1e-14
AF177386-1|AAD51369.1| 3584|Drosophila melanogaster huntingtin h... 80 3e-14
>AF147779-1|AAF03256.1| 3583|Drosophila melanogaster Huntington
disease protein homolog protein.
Length = 3583
Score = 81.0 bits (191), Expect = 1e-14
Identities = 90/352 (25%), Positives = 156/352 (44%), Gaps = 19/352 (5%)
Query: 219 STASESLDDKASLKRKPLMPATSLRANFVGHFYNEPFYMKLYEGLRAAYSNHKINLDPKS 278
S +S S K+ L + PA +L+A +G+F + YMKLY LR A ++KI ++ ++
Sbjct: 1625 SGSSSSKQPKSELFARE-QPAATLQA--LGYFAGDYVYMKLYNILRGANDSYKITINQEA 1681
Query: 279 -SIFHTFLSTTLDCLAVQLE--LSTEKEFGSVTEEILYYLKAIMPLCADNTVYCVTQLLK 335
S+ L T L +++ LE S + EEIL+YL ++ V C+ QLLK
Sbjct: 1682 GSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVACLRQLLK 1741
Query: 336 CLFGTNMVAQYDDYMSISDKN--EGSRQTSFCEDVWTRADHGSRRSSV---GSNASQKLC 390
LF N +Q S N E +F + G SS N+ +
Sbjct: 1742 YLFAQNYASQVRLQPSAIGGNGSEIGHHAAFMRPYFAAKGRGHGASSTLLPTINSKPAVA 1801
Query: 391 LDIKNPRMAAERQLLIA--LENFAK--NKSDRKWSTNKEELEKYIKLFEPVVIQSLKSYT 446
+ + RQ + A L++ + + + + IKLFEP+VI L +
Sbjct: 1802 VGSQRGAPTDARQPIDAGPLQDMGMLFVHGLQPPTPPAGDCVRLIKLFEPMVIYCLTLF- 1860
Query: 447 MQNDIPXXXXXXXXXXXXXXXXXXYCMLDNDLIFIGFLMKQLDLFEQHEIPNCCDLVNSI 506
M+++ Y +LD+ + ++ +DL E N +V +
Sbjct: 1861 MKSNALVQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDRNAFIMVPPM 1920
Query: 507 LMFLVQLSSSKHHTKKIIEIPKLIQLCDGLMASGA-HAECIAGLEPVAVKVF 557
L FLVQL+ +++I IPK+I + + L+A+G+ + L+ ++ ++F
Sbjct: 1921 LRFLVQLTHKS--DRQLITIPKIISITNNLLANGSVRVVALLALKTLSYELF 1970
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/210 (22%), Positives = 88/210 (41%), Gaps = 27/210 (12%)
Query: 1414 TRHVTVDSLVAVTVENVSKALAVREIWMELNADSNANRTQSAISCLYAVVKYLVKDTKPL 1473
TR + + V + V+ L +W ELNA S+ + + L +V + +++DT
Sbjct: 2699 TRQESEQDALGVLLATVNTLLQQPRVWRELNASSDPSLRCELLDLLDSVARCILQDTIFY 2758
Query: 1474 VLKHYMRTDDSGPKPDILITGDKLVTLVEYWEDNFYAGHGYVMPKCYKKPLESMLVSLAR 1533
R GP P + + T +E G V+ + L+ LAR
Sbjct: 2759 RRHRRDRNKAKGPAPQAIFLAKLIETQIEIES----LASGRVLAGVEEARLQFAGQDLAR 2814
Query: 1534 LDVVSNVALIPPIAWSTVE--------------VAMKKDQLQKIE-------LPLQALQD 1572
V ++L+ I S + + DQ Q+ + +P+ +L D
Sbjct: 2815 FQVA--LSLVTSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQQADGKLPSIPVDSLSD 2872
Query: 1573 QDVLKAFLFRVNLIGWSNKKQFEEIWVGLL 1602
DVL+ F+ R+++ G++ ++QFEE ++ L
Sbjct: 2873 VDVLRQFVKRLSIFGFTTRQQFEEYFMTCL 2902
>AF146362-1|AAF03255.1| 3583|Drosophila melanogaster Huntington
disease protein homolog protein.
Length = 3583
Score = 81.0 bits (191), Expect = 1e-14
Identities = 90/352 (25%), Positives = 156/352 (44%), Gaps = 19/352 (5%)
Query: 219 STASESLDDKASLKRKPLMPATSLRANFVGHFYNEPFYMKLYEGLRAAYSNHKINLDPKS 278
S +S S K+ L + PA +L+A +G+F + YMKLY LR A ++KI ++ ++
Sbjct: 1625 SGSSSSKQPKSELFARE-QPAATLQA--LGYFAGDYVYMKLYNILRGANDSYKITINQEA 1681
Query: 279 -SIFHTFLSTTLDCLAVQLE--LSTEKEFGSVTEEILYYLKAIMPLCADNTVYCVTQLLK 335
S+ L T L +++ LE S + EEIL+YL ++ V C+ QLLK
Sbjct: 1682 GSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVACLRQLLK 1741
Query: 336 CLFGTNMVAQYDDYMSISDKN--EGSRQTSFCEDVWTRADHGSRRSSV---GSNASQKLC 390
LF N +Q S N E +F + G SS N+ +
Sbjct: 1742 YLFAQNYASQVRLQPSAIGGNGSEIGHHAAFMRPYFAAKGRGHGASSTLLPTINSKPAVA 1801
Query: 391 LDIKNPRMAAERQLLIA--LENFAK--NKSDRKWSTNKEELEKYIKLFEPVVIQSLKSYT 446
+ + RQ + A L++ + + + + IKLFEP+VI L +
Sbjct: 1802 VGSQRGAPTDARQPIDAGPLQDMGMLFVHGLQPPTPPAGDCVRLIKLFEPMVIYCLTLF- 1860
Query: 447 MQNDIPXXXXXXXXXXXXXXXXXXYCMLDNDLIFIGFLMKQLDLFEQHEIPNCCDLVNSI 506
M+++ Y +LD+ + ++ +DL E N +V +
Sbjct: 1861 MKSNALVQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDRNAFIMVPPM 1920
Query: 507 LMFLVQLSSSKHHTKKIIEIPKLIQLCDGLMASGA-HAECIAGLEPVAVKVF 557
L FLVQL+ +++I IPK+I + + L+A+G+ + L+ ++ ++F
Sbjct: 1921 LRFLVQLTHKS--DRQLITIPKIISITNNLLANGSVRVVALLALKTLSYELF 1970
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/210 (22%), Positives = 88/210 (41%), Gaps = 27/210 (12%)
Query: 1414 TRHVTVDSLVAVTVENVSKALAVREIWMELNADSNANRTQSAISCLYAVVKYLVKDTKPL 1473
TR + + V + V+ L +W ELNA S+ + + L +V + +++DT
Sbjct: 2699 TRQESEQDALGVLLATVNTLLQQPRVWRELNASSDPSLRCELLDLLDSVARCILQDTIFY 2758
Query: 1474 VLKHYMRTDDSGPKPDILITGDKLVTLVEYWEDNFYAGHGYVMPKCYKKPLESMLVSLAR 1533
R GP P + + T +E G V+ + L+ LAR
Sbjct: 2759 RRHRRDRNKAKGPAPQAIFLAKLIETQIEIES----LASGRVLAGVEEARLQFAGQDLAR 2814
Query: 1534 LDVVSNVALIPPIAWSTVE--------------VAMKKDQLQKIE-------LPLQALQD 1572
V ++L+ I S + + DQ Q+ + +P+ +L D
Sbjct: 2815 FQVA--LSLVTSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQQADGKLPSIPVDSLSD 2872
Query: 1573 QDVLKAFLFRVNLIGWSNKKQFEEIWVGLL 1602
DVL+ F+ R+++ G++ ++QFEE ++ L
Sbjct: 2873 VDVLRQFVKRLSIFGFTTRQQFEEYFMTCL 2902
>AE014297-4258|AAF56808.1| 3583|Drosophila melanogaster CG9995-PA
protein.
Length = 3583
Score = 81.0 bits (191), Expect = 1e-14
Identities = 90/352 (25%), Positives = 156/352 (44%), Gaps = 19/352 (5%)
Query: 219 STASESLDDKASLKRKPLMPATSLRANFVGHFYNEPFYMKLYEGLRAAYSNHKINLDPKS 278
S +S S K+ L + PA +L+A +G+F + YMKLY LR A ++KI ++ ++
Sbjct: 1625 SGSSSSKQPKSELFARE-QPAATLQA--LGYFAGDYVYMKLYNILRGANDSYKITINQEA 1681
Query: 279 -SIFHTFLSTTLDCLAVQLE--LSTEKEFGSVTEEILYYLKAIMPLCADNTVYCVTQLLK 335
S+ L T L +++ LE S + EEIL+YL ++ V C+ QLLK
Sbjct: 1682 GSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVACLRQLLK 1741
Query: 336 CLFGTNMVAQYDDYMSISDKN--EGSRQTSFCEDVWTRADHGSRRSSV---GSNASQKLC 390
LF N +Q S N E +F + G SS N+ +
Sbjct: 1742 YLFAQNYASQVRLQPSAIGGNGSEIGHHAAFMRPYFAAKGRGHGASSTLLPTINSKPAVA 1801
Query: 391 LDIKNPRMAAERQLLIA--LENFAK--NKSDRKWSTNKEELEKYIKLFEPVVIQSLKSYT 446
+ + RQ + A L++ + + + + IKLFEP+VI L +
Sbjct: 1802 VGSQRGAPTDARQPIDAGPLQDMGMLFVHGLQPPTPPAGDCVRLIKLFEPMVIYCLTLF- 1860
Query: 447 MQNDIPXXXXXXXXXXXXXXXXXXYCMLDNDLIFIGFLMKQLDLFEQHEIPNCCDLVNSI 506
M+++ Y +LD+ + ++ +DL E N +V +
Sbjct: 1861 MKSNALVQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDRNAFIMVPPM 1920
Query: 507 LMFLVQLSSSKHHTKKIIEIPKLIQLCDGLMASGA-HAECIAGLEPVAVKVF 557
L FLVQL+ +++I IPK+I + + L+A+G+ + L+ ++ ++F
Sbjct: 1921 LRFLVQLTHKS--DRQLITIPKIISITNNLLANGSVRVVALLALKTLSYELF 1970
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/210 (22%), Positives = 88/210 (41%), Gaps = 27/210 (12%)
Query: 1414 TRHVTVDSLVAVTVENVSKALAVREIWMELNADSNANRTQSAISCLYAVVKYLVKDTKPL 1473
TR + + V + V+ L +W ELNA S+ + + L +V + +++DT
Sbjct: 2699 TRQESEQDALGVLLATVNTLLQQPRVWRELNASSDPSLRCELLDLLDSVARCILQDTIFY 2758
Query: 1474 VLKHYMRTDDSGPKPDILITGDKLVTLVEYWEDNFYAGHGYVMPKCYKKPLESMLVSLAR 1533
R GP P + + T +E G V+ + L+ LAR
Sbjct: 2759 RRHRRDRNKAKGPAPQAIFLAKLIETQIEIES----LASGRVLAGVEEARLQFAGQDLAR 2814
Query: 1534 LDVVSNVALIPPIAWSTVE--------------VAMKKDQLQKIE-------LPLQALQD 1572
V ++L+ I S + + DQ Q+ + +P+ +L D
Sbjct: 2815 FQVA--LSLVTSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQQADGKLPSIPVDSLSD 2872
Query: 1573 QDVLKAFLFRVNLIGWSNKKQFEEIWVGLL 1602
DVL+ F+ R+++ G++ ++QFEE ++ L
Sbjct: 2873 VDVLRQFVKRLSIFGFTTRQQFEEYFMTCL 2902
>AF177386-1|AAD51369.1| 3584|Drosophila melanogaster huntingtin
homolog protein.
Length = 3584
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/353 (25%), Positives = 156/353 (44%), Gaps = 20/353 (5%)
Query: 219 STASESLDDKASLKRKPLMPATSLRANFVGHFYNEPFYMKLYEGLRAAYSNHKINLDPKS 278
S +S S K+ L + PA +L+A +G+F + YMKLY LR A ++KI ++ ++
Sbjct: 1625 SGSSSSKQPKSELFARE-QPAATLQA--LGYFAGDYVYMKLYNILRGANDSYKITINQEA 1681
Query: 279 -SIFHTFLSTTLDCLAVQLE--LSTEKEFGSVTEEILYYLKAIMPLCADNTVYCVTQLLK 335
S+ L T L +++ LE S + EEIL+YL ++ V C+ QLLK
Sbjct: 1682 GSLLICLLKTCLHAVSLCLEGMASASPPELKLIEEILHYLTRLINYAPAECVACLRQLLK 1741
Query: 336 CLFGTNMVAQYDDYMSISDKNEGS---RQTSFCEDVWTRADHGSRRSSV---GSNASQKL 389
LF N +Q S G+ +F + G SS N+ +
Sbjct: 1742 YLFAQNYASQVRLQPSAGIGGNGTGIGHHAAFMRPYFAAKGRGHGASSTLLPTINSKPAV 1801
Query: 390 CLDIKNPRMAAERQLLIA--LENFAK--NKSDRKWSTNKEELEKYIKLFEPVVIQSLKSY 445
+ + RQ + A L++ + + + + IKLFEP+VI L +
Sbjct: 1802 AVGSQRGAPTDARQPIDAGPLQDMGMLFVHGLQPPTPPAGDCVRLIKLFEPMVIYCLTLF 1861
Query: 446 TMQNDIPXXXXXXXXXXXXXXXXXXYCMLDNDLIFIGFLMKQLDLFEQHEIPNCCDLVNS 505
M+++ Y +LD+ + ++ +DL E N +V
Sbjct: 1862 -MKSNALVQAPILRLLSQLLDLNVTYSILDSKNVIFDQVLSNMDLIEGGIDRNAFIMVPP 1920
Query: 506 ILMFLVQLSSSKHHTKKIIEIPKLIQLCDGLMASGA-HAECIAGLEPVAVKVF 557
+L FLVQL+ +++I IPK+I + + L+A+G+ + L+ ++ ++F
Sbjct: 1921 MLRFLVQLTHKS--DRQLITIPKIISITNNLLANGSVRVVALLALKTLSYELF 1971
Score = 44.4 bits (100), Expect = 0.002
Identities = 48/210 (22%), Positives = 88/210 (41%), Gaps = 27/210 (12%)
Query: 1414 TRHVTVDSLVAVTVENVSKALAVREIWMELNADSNANRTQSAISCLYAVVKYLVKDTKPL 1473
TR + + V + V+ L +W ELNA S+ + + L +V + +++DT
Sbjct: 2700 TRQESEQDALGVLLATVNTLLQQPRVWRELNASSDPSLRCELLDLLDSVARCILQDTIFY 2759
Query: 1474 VLKHYMRTDDSGPKPDILITGDKLVTLVEYWEDNFYAGHGYVMPKCYKKPLESMLVSLAR 1533
R GP P + + T +E G V+ + L+ LAR
Sbjct: 2760 RRHRRDRNKAKGPAPQAIFLAKLIETQIEIES----LASGRVLAGVEEARLQFAGQDLAR 2815
Query: 1534 LDVVSNVALIPPIAWSTVE--------------VAMKKDQLQKIE-------LPLQALQD 1572
V ++L+ I S + + DQ Q+ + +P+ +L D
Sbjct: 2816 FQVA--LSLVTSIGISLLRTHQFYAYAVTPHELIQQPGDQQQEQQADGKLPSIPVDSLSD 2873
Query: 1573 QDVLKAFLFRVNLIGWSNKKQFEEIWVGLL 1602
DVL+ F+ R+++ G++ ++QFEE ++ L
Sbjct: 2874 VDVLRQFVKRLSIFGFTTRQQFEEYFMTCL 2903
Database: fruitfly
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 24,830,863
Number of sequences in database: 52,641
Lambda K H
0.321 0.135 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,925,424
Number of Sequences: 52641
Number of extensions: 3352552
Number of successful extensions: 8377
Number of sequences better than 10.0: 4
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 8337
Number of HSP's gapped (non-prelim): 28
length of query: 1855
length of database: 24,830,863
effective HSP length: 96
effective length of query: 1759
effective length of database: 19,777,327
effective search space: 34788318193
effective search space used: 34788318193
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 69 (31.9 bits)
- SilkBase 1999-2023 -