Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002220-TA|BGIBMGA002220-PA|undefined
(660 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC021134-1|AAH21134.1| 903|Homo sapiens centrobin, centrosomal ... 111 8e-24
BC014055-1|AAH14055.3| 805|Homo sapiens CNTROB protein protein. 111 8e-24
AY160227-1|AAO22136.1| 925|Homo sapiens centrobin beta protein. 111 8e-24
AY160226-1|AAO22135.1| 903|Homo sapiens centrobin alpha protein. 111 8e-24
AF331638-1|AAL56068.2| 903|Homo sapiens PP1221 protein. 111 1e-23
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 68 9e-11
BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein. 68 9e-11
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 68 9e-11
AK057990-1|BAB71626.1| 502|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein. 68 1e-10
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 65 9e-10
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 64 1e-09
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 64 2e-09
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 64 2e-09
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 64 2e-09
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 64 2e-09
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 64 2e-09
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 64 2e-09
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 64 2e-09
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 64 2e-09
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 64 2e-09
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 64 2e-09
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 64 2e-09
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 64 2e-09
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 64 2e-09
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 62 5e-09
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 62 5e-09
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 62 5e-09
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 62 8e-09
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 62 8e-09
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 62 8e-09
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 62 8e-09
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 62 8e-09
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 62 8e-09
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 61 1e-08
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 61 1e-08
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 61 1e-08
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 61 1e-08
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 60 2e-08
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 60 2e-08
BC063115-1|AAH63115.1| 695|Homo sapiens RNF20 protein protein. 60 2e-08
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 60 2e-08
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 60 2e-08
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK000697-1|BAA91326.1| 670|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK000389-1|BAA91134.1| 682|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 60 2e-08
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 60 2e-08
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 60 2e-08
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 60 2e-08
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 60 2e-08
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 60 3e-08
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 60 3e-08
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 60 3e-08
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 60 3e-08
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 60 3e-08
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 60 3e-08
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 60 3e-08
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 59 4e-08
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 59 4e-08
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 59 4e-08
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 59 4e-08
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 59 4e-08
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 59 4e-08
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 59 4e-08
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 59 4e-08
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 59 4e-08
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 59 4e-08
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 58 7e-08
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 58 7e-08
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 58 7e-08
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 58 7e-08
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 58 7e-08
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 58 7e-08
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 58 7e-08
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 58 7e-08
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 58 7e-08
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 58 7e-08
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 58 7e-08
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 58 1e-07
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 58 1e-07
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 58 1e-07
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 58 1e-07
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 58 1e-07
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 58 1e-07
BC062749-1|AAH62749.1| 383|Homo sapiens CCDC73 protein protein. 58 1e-07
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 58 1e-07
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 58 1e-07
BC101517-1|AAI01518.1| 637|Homo sapiens RAB11 family interactin... 58 1e-07
BC093914-1|AAH93914.1| 637|Homo sapiens RAB11 family interactin... 58 1e-07
AY169244-1|AAO21970.1| 637|Homo sapiens rab11-family interactin... 58 1e-07
AJ314646-1|CAC44535.1| 609|Homo sapiens hypothetical protein pr... 58 1e-07
AB058724-1|BAB47450.1| 609|Homo sapiens KIAA1821 protein protein. 58 1e-07
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 57 2e-07
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 57 2e-07
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 57 2e-07
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 57 2e-07
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 57 2e-07
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 57 2e-07
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 57 2e-07
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 56 3e-07
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 56 3e-07
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 56 3e-07
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 56 3e-07
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 56 3e-07
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 56 3e-07
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 56 3e-07
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 56 3e-07
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 56 3e-07
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 56 4e-07
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 56 4e-07
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 56 4e-07
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 56 4e-07
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 56 4e-07
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 56 4e-07
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 56 4e-07
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 56 4e-07
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 56 4e-07
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 56 4e-07
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 56 4e-07
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 56 4e-07
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 56 4e-07
AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short iso... 56 4e-07
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 56 4e-07
AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein. 56 4e-07
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 56 4e-07
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 56 4e-07
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 56 5e-07
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 56 5e-07
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 56 5e-07
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 56 5e-07
AK074847-1|BAC11241.1| 432|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AY639646-1|AAX19141.1| 572|Homo sapiens prefoldin subunit 6-lik... 55 7e-07
AL445669-8|CAH70752.1| 783|Homo sapiens novel protein protein. 55 7e-07
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 55 7e-07
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 55 7e-07
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 55 7e-07
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 55 7e-07
AL138788-1|CAI22439.1| 783|Homo sapiens novel protein protein. 55 7e-07
AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens ... 55 7e-07
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 55 7e-07
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 55 7e-07
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 55 9e-07
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 55 9e-07
X58677-1|CAA41528.1| 608|Homo sapiens hemidesmosomal plaque pr... 55 9e-07
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 55 9e-07
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 55 9e-07
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 55 9e-07
AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-... 55 9e-07
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 55 9e-07
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 55 9e-07
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 55 9e-07
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 54 1e-06
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 54 1e-06
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 54 1e-06
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro... 54 1e-06
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 54 1e-06
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 54 2e-06
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 54 2e-06
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 54 2e-06
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 54 2e-06
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 54 2e-06
AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AK097424-1|BAC05045.1| 535|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 54 2e-06
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 54 2e-06
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 54 2e-06
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 54 2e-06
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 54 2e-06
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 54 2e-06
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 54 2e-06
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 54 2e-06
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 54 2e-06
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 54 2e-06
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 54 2e-06
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 54 2e-06
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 54 2e-06
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 54 2e-06
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 54 2e-06
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 54 2e-06
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 54 2e-06
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 54 2e-06
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 54 2e-06
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 54 2e-06
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 53 3e-06
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 53 3e-06
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 53 3e-06
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 3e-06
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 53 3e-06
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 53 3e-06
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 53 3e-06
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 3e-06
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 3e-06
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 53 3e-06
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 53 3e-06
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 53 3e-06
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 53 3e-06
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 53 3e-06
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 53 3e-06
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 53 3e-06
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 53 3e-06
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 53 3e-06
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 53 3e-06
AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen... 53 3e-06
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 53 3e-06
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 53 3e-06
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 53 3e-06
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 53 3e-06
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 53 3e-06
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 53 4e-06
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 53 4e-06
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 53 4e-06
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 53 4e-06
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 53 4e-06
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 53 4e-06
AF179308-1|AAD51855.1| 1232|Homo sapiens KIF4 protein. 53 4e-06
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 52 5e-06
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 52 5e-06
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 52 5e-06
BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein. 52 5e-06
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 52 5e-06
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 52 5e-06
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 52 5e-06
AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein. 52 5e-06
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 52 5e-06
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 52 5e-06
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 52 5e-06
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 52 6e-06
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 52 6e-06
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 52 6e-06
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 52 6e-06
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 52 6e-06
M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein. 52 6e-06
M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein. 52 6e-06
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 52 6e-06
M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblas... 52 6e-06
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 52 6e-06
BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 52 6e-06
AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110... 52 6e-06
AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 52 6e-06
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 52 6e-06
AF304450-1|AAG41949.1| 359|Homo sapiens sarcolemmal associated ... 52 6e-06
AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein. 52 6e-06
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 52 6e-06
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 52 6e-06
U33821-1|AAA75595.2| 747|Homo sapiens tax1-binding protein TXBP... 52 9e-06
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 52 9e-06
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 52 9e-06
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 52 9e-06
AL607144-1|CAI40565.1| 1163|Homo sapiens KIAA0774 protein. 52 9e-06
AL596114-1|CAI39910.1| 1163|Homo sapiens KIAA0774 protein. 52 9e-06
AL596092-1|CAI40386.1| 1163|Homo sapiens KIAA0774 protein. 52 9e-06
AL160255-1|CAI41204.1| 1163|Homo sapiens KIAA0774 protein. 52 9e-06
AK021545-1|BAB13841.1| 436|Homo sapiens protein ( Homo sapiens ... 52 9e-06
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 52 9e-06
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 52 9e-06
AB018317-1|BAA34494.2| 1381|Homo sapiens KIAA0774 protein protein. 52 9e-06
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 51 1e-05
BC130535-1|AAI30536.1| 867|Homo sapiens C18orf34 protein protein. 51 1e-05
BC091517-1|AAH91517.1| 849|Homo sapiens C18orf34 protein protein. 51 1e-05
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 51 1e-05
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 51 1e-05
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AK125971-1|BAC86369.1| 483|Homo sapiens protein ( Homo sapiens ... 51 1e-05
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 51 1e-05
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 51 1e-05
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 51 1e-05
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 51 1e-05
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 51 1e-05
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 51 1e-05
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 51 1e-05
BC050548-1|AAH50548.1| 1127|Homo sapiens KIF4A protein protein. 51 1e-05
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 51 1e-05
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 51 1e-05
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 51 1e-05
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 51 1e-05
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 51 1e-05
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 51 1e-05
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 51 1e-05
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 51 1e-05
AL357752-3|CAI41487.1| 1232|Homo sapiens kinesin family member 4... 51 1e-05
AL139398-5|CAI41024.1| 1232|Homo sapiens kinesin family member 4... 51 1e-05
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 51 1e-05
AB208797-1|BAD92034.1| 1235|Homo sapiens Chromosome-associated k... 51 1e-05
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 51 1e-05
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 50 2e-05
BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein. 50 2e-05
BC003664-1|AAH03664.1| 787|Homo sapiens Unknown (protein for IM... 50 2e-05
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 50 2e-05
AJ271784-1|CAB75427.1| 1232|Homo sapiens chromokinesin protein. 50 2e-05
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 50 2e-05
AF071592-1|AAD05492.2| 1232|Homo sapiens kinesin superfamily mot... 50 2e-05
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 50 2e-05
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 50 3e-05
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 50 3e-05
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 50 3e-05
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 50 3e-05
BC126208-1|AAI26209.1| 1161|Homo sapiens SMC1B protein protein. 50 3e-05
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 50 3e-05
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 50 3e-05
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 50 3e-05
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 50 3e-05
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 50 3e-05
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 50 3e-05
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 50 3e-05
X04588-1|CAB37185.1| 248|Homo sapiens protein ( Human 2.5 kb mR... 50 3e-05
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 50 3e-05
M55210-1|AAA59492.1| 1609|Homo sapiens laminin B2 chain protein. 50 3e-05
J03202-1|AAA59488.1| 1609|Homo sapiens LAMB2 protein. 50 3e-05
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 50 3e-05
BC132871-1|AAI32872.1| 745|Homo sapiens cutaneous T-cell lympho... 50 3e-05
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 50 3e-05
BC072428-1|AAH72428.1| 248|Homo sapiens tropomyosin 3 protein. 50 3e-05
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 50 3e-05
BC031065-1|AAH31065.2| 780|Homo sapiens CTAGE1 protein protein. 50 3e-05
BC015403-1|AAH15403.1| 248|Homo sapiens tropomyosin 3 protein. 50 3e-05
BC000771-1|AAH00771.1| 248|Homo sapiens tropomyosin 3 protein. 50 3e-05
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 50 3e-05
AL590431-7|CAH71264.1| 248|Homo sapiens tropomyosin 3 protein. 50 3e-05
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 50 3e-05
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 50 3e-05
AL450304-5|CAI14877.1| 1609|Homo sapiens laminin, gamma 1 (forme... 50 3e-05
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 50 3e-05
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 50 3e-05
AL354953-3|CAH70981.1| 1609|Homo sapiens laminin, gamma 1 (forme... 50 3e-05
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 50 3e-05
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 50 3e-05
AK126038-1|BAC86407.1| 829|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AF273058-1|AAK63198.1| 754|Homo sapiens CTAGE-2 protein. 50 3e-05
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 50 3e-05
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 50 3e-05
Z26653-1|CAA81394.1| 3110|Homo sapiens laminin M chain (merosin)... 49 5e-05
U66796-1|AAB18388.1| 3110|Homo sapiens laminin alpha 2 chain pro... 49 5e-05
CR769776-10|CAI95382.1| 354|Homo sapiens coiled-coil domain con... 49 5e-05
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 49 5e-05
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 49 5e-05
BC028682-1|AAH28682.1| 411|Homo sapiens CCDC91 protein protein. 49 5e-05
BC028119-1|AAH28119.1| 391|Homo sapiens testis expressed 9 prot... 49 5e-05
AY289196-1|AAP42284.1| 441|Homo sapiens p56 protein. 49 5e-05
AL669984-2|CAI16682.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL607144-2|CAI40566.1| 348|Homo sapiens KIAA0774 protein. 49 5e-05
AL596114-2|CAI39912.1| 348|Homo sapiens KIAA0774 protein. 49 5e-05
AL590613-1|CAH70771.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL583853-1|CAH70492.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL513527-1|CAI15185.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL445439-1|CAH72952.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL356124-1|CAI22470.1| 3122|Homo sapiens laminin, alpha 2 (meros... 49 5e-05
AL021391-1|CAI18928.1| 1235|Homo sapiens structural maintenance ... 49 5e-05
AL008718-2|CAI17945.1| 1235|Homo sapiens structural maintenance ... 49 5e-05
AJ504806-1|CAD43404.2| 1235|Homo sapiens SMC1beta protein protein. 49 5e-05
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 49 5e-05
AB208922-1|BAD92159.1| 1853|Homo sapiens laminin alpha 2 subunit... 49 5e-05
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 49 5e-05
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 49 6e-05
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 49 6e-05
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 49 6e-05
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 49 6e-05
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 49 6e-05
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 49 6e-05
AL133410-3|CAI10976.1| 322|Homo sapiens tropomyosin 2 (beta) pr... 49 6e-05
AF011368-1|AAB84386.1| 761|Homo sapiens CEV14 protein. 49 6e-05
AB032945-1|BAA86433.2| 1854|Homo sapiens KIAA1119 protein protein. 49 6e-05
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 48 8e-05
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 48 8e-05
BC096345-1|AAH96345.1| 339|Homo sapiens OFD1 protein protein. 48 8e-05
BC096344-1|AAH96344.1| 972|Homo sapiens OFD1 protein protein. 48 8e-05
AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein pro... 48 8e-05
AY004867-1|AAF87083.1| 247|Homo sapiens tropomyosin isoform pro... 48 8e-05
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 48 8e-05
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 48 8e-05
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 48 8e-05
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 48 8e-05
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 48 8e-05
AK125783-1|BAC86289.1| 731|Homo sapiens protein ( Homo sapiens ... 48 8e-05
AK025336-1|BAB15114.1| 963|Homo sapiens protein ( Homo sapiens ... 48 8e-05
AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain prot... 48 8e-05
AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain prot... 48 8e-05
AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein. 48 8e-05
AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein. 48 8e-05
AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein. 48 8e-05
AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein. 48 8e-05
AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein. 48 8e-05
AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein. 48 8e-05
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 48 8e-05
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 48 1e-04
X13939-1|CAA32122.1| 328|Homo sapiens laminin B2 protein. 48 1e-04
U77845-1|AAB52993.1| 469|Homo sapiens hTRIP protein. 48 1e-04
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 48 1e-04
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 48 1e-04
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 48 1e-04
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 48 1e-04
BC129985-1|AAI29986.1| 348|Homo sapiens KIAA0774 protein. 48 1e-04
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 48 1e-04
BC119654-1|AAI19655.1| 348|Homo sapiens KIAA0774 protein. 48 1e-04
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 48 1e-04
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 48 1e-04
BC032481-1|AAH32481.1| 348|Homo sapiens KIAA0774 protein. 48 1e-04
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 48 1e-04
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 48 1e-04
AL590377-2|CAI14630.2| 1406|Homo sapiens chromosome 9 open readi... 48 1e-04
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 48 1e-04
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 48 1e-04
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 48 1e-04
AL354738-1|CAI16195.2| 1406|Homo sapiens chromosome 9 open readi... 48 1e-04
AL354711-1|CAH72682.2| 1406|Homo sapiens chromosome 9 open readi... 48 1e-04
AL163203-2|CAB90394.1| 424|Homo sapiens PRED4 protein. 48 1e-04
AL162725-3|CAH70424.1| 1406|Homo sapiens chromosome 9 open readi... 48 1e-04
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 48 1e-04
AL133214-3|CAH70743.2| 1406|Homo sapiens chromosome 9 open readi... 48 1e-04
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 48 1e-04
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 48 1e-04
AF277375-1|AAF86334.1| 1103|Homo sapiens chromokinesin protein. 48 1e-04
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 48 1e-04
AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein. 48 1e-04
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 48 1e-04
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 48 1e-04
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 48 1e-04
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 48 1e-04
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 48 1e-04
CR533556-1|CAG38587.1| 789|Homo sapiens TAX1BP1 protein. 48 1e-04
CR457056-1|CAG33337.1| 747|Homo sapiens TAX1BP1 protein. 48 1e-04
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 48 1e-04
BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein. 48 1e-04
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 48 1e-04
BC060803-1|AAH60803.1| 715|Homo sapiens chromosome 6 open readi... 48 1e-04
BC051911-1|AAH51911.1| 757|Homo sapiens chromosome 13 open read... 48 1e-04
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 48 1e-04
BC007433-1|AAH07433.1| 284|Homo sapiens tropomyosin 1 (alpha) p... 48 1e-04
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 48 1e-04
AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis... 48 1e-04
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 48 1e-04
AL391384-3|CAI15673.1| 757|Homo sapiens RP11-505F3.1 protein. 48 1e-04
AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transpor... 48 1e-04
AL354720-1|CAI14869.1| 757|Homo sapiens RP11-505F3.1 protein. 48 1e-04
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AK026958-1|BAB15602.1| 715|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AK024004-1|BAB14769.1| 519|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AF330046-1|AAL37481.1| 757|Homo sapiens progesterone-induced bl... 48 1e-04
AF268075-1|AAG03025.1| 747|Homo sapiens TRAF6-binding protein T... 48 1e-04
AF266285-1|AAF72535.1| 693|Homo sapiens golgin-like protein pro... 48 1e-04
AF090891-1|AAF24016.1| 747|Homo sapiens PRO0105 protein. 48 1e-04
AC004549-1|AAC13359.2| 596|Homo sapiens unknown protein. 48 1e-04
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 48 1e-04
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 48 1e-04
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 48 1e-04
DQ120714-1|ABC40673.1| 247|Homo sapiens rcTPM3 protein. 47 2e-04
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 47 2e-04
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 47 2e-04
BC080185-1|AAH80185.1| 417|Homo sapiens SMC1A protein protein. 47 2e-04
BC077732-1|AAH77732.1| 662|Homo sapiens FKBP15 protein protein. 47 2e-04
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 47 2e-04
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 47 2e-04
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 47 2e-04
BC000099-1|AAH00099.4| 655|Homo sapiens RRBP1 protein protein. 47 2e-04
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 47 2e-04
AL449305-3|CAI10964.1| 1244|Homo sapiens FK506 binding protein 1... 47 2e-04
AL449105-1|CAI95402.1| 1244|Homo sapiens FK506 binding protein 1... 47 2e-04
AL031283-7|CAI21429.1| 647|Homo sapiens forkhead-associated (FH... 47 2e-04
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 47 2e-04
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 47 2e-04
AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein. 47 2e-04
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 47 2e-04
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 47 2e-04
AB023222-1|BAA76849.1| 1055|Homo sapiens KIAA1005 protein protein. 47 2e-04
AB014574-1|BAA31649.1| 1234|Homo sapiens KIAA0674 protein protein. 47 2e-04
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 47 2e-04
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 47 2e-04
BC133019-1|AAI33020.1| 1427|Homo sapiens LOC650001 protein protein. 47 2e-04
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 47 2e-04
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 47 2e-04
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 47 2e-04
BC050358-1|AAH50358.1| 789|Homo sapiens Tax1 (human T-cell leuk... 47 2e-04
BC041806-1|AAH41806.1| 698|Homo sapiens C13orf24 protein protein. 47 2e-04
BC039102-1|AAH39102.1| 268|Homo sapiens Unknown (protein for IM... 47 2e-04
BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein. 47 2e-04
BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain cont... 47 2e-04
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 47 2e-04
BC016691-1|AAH16691.1| 617|Homo sapiens Unknown (protein for IM... 47 2e-04
AY644768-1|AAV85456.1| 731|Homo sapiens cell proliferation-indu... 47 2e-04
AY166853-1|AAO17292.1| 1317|Homo sapiens kinesin motor protein p... 47 2e-04
AL590431-5|CAH71266.1| 248|Homo sapiens tropomyosin 3 protein. 47 2e-04
AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protei... 47 2e-04
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 47 2e-04
AL118509-3|CAI43063.2| 1392|Homo sapiens chromosome 20 open read... 47 2e-04
AL118509-2|CAM28305.1| 1317|Homo sapiens chromosome 20 open read... 47 2e-04
AL117376-3|CAI43180.2| 1392|Homo sapiens chromosome 20 open read... 47 2e-04
AL117376-2|CAI43181.2| 1317|Homo sapiens chromosome 20 open read... 47 2e-04
AL049794-2|CAI22745.2| 1392|Homo sapiens chromosome 20 open read... 47 2e-04
AL049794-1|CAM28307.1| 1317|Homo sapiens chromosome 20 open read... 47 2e-04
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AK000283-1|BAA91052.1| 1084|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AJ132949-1|CAB36967.1| 585|Homo sapiens rfg5 protein protein. 47 2e-04
AF474157-1|AAL84570.1| 247|Homo sapiens TPMsk3 protein. 47 2e-04
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 47 2e-04
AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein. 47 2e-04
>BC021134-1|AAH21134.1| 903|Homo sapiens centrobin, centrosomal
BRCA2 interacting protein protein.
Length = 903
Score = 111 bits (267), Expect = 8e-24
Identities = 86/384 (22%), Positives = 170/384 (44%), Gaps = 5/384 (1%)
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRA 316
L+ E +R+HCE I AVA+ DR KD I +L + R+ +R
Sbjct: 190 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRH 249
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL 376
E + L + E + + Q+ + E L + ++ + Q+ + Q E+++L
Sbjct: 250 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL 309
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE E + + L + + VL+E D ++ L ALE+E+
Sbjct: 310 EE----ERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQ 365
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + E + +Q + L +E+ +++ E + + A+++ ++ + + ++
Sbjct: 366 EHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRE 425
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
D L E+ ++ E Q+ +L+ QLE V +L + QE R + R +
Sbjct: 426 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQL 485
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
++ +++ Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +
Sbjct: 486 QDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQ 545
Query: 616 RGETAARLHAALQAHWRHALRILA 639
R E RL A LQAHW A ++L+
Sbjct: 546 RVELVERLQAMLQAHWDEANQLLS 569
>BC014055-1|AAH14055.3| 805|Homo sapiens CNTROB protein protein.
Length = 805
Score = 111 bits (267), Expect = 8e-24
Identities = 86/384 (22%), Positives = 170/384 (44%), Gaps = 5/384 (1%)
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRA 316
L+ E +R+HCE I AVA+ DR KD I +L + R+ +R
Sbjct: 91 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRH 150
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL 376
E + L + E + + Q+ + E L + ++ + Q+ + Q E+++L
Sbjct: 151 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL 210
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE E + + L + + VL+E D ++ L ALE+E+
Sbjct: 211 EE----ERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQ 266
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + E + +Q + L +E+ +++ E + + A+++ ++ + + ++
Sbjct: 267 EHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRE 326
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
D L E+ ++ E Q+ +L+ QLE V +L + QE R + R +
Sbjct: 327 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQL 386
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
++ +++ Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +
Sbjct: 387 QDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQ 446
Query: 616 RGETAARLHAALQAHWRHALRILA 639
R E RL A LQAHW A ++L+
Sbjct: 447 RVELVERLQAMLQAHWDEANQLLS 470
>AY160227-1|AAO22136.1| 925|Homo sapiens centrobin beta protein.
Length = 925
Score = 111 bits (267), Expect = 8e-24
Identities = 86/384 (22%), Positives = 170/384 (44%), Gaps = 5/384 (1%)
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRA 316
L+ E +R+HCE I AVA+ DR KD I +L + R+ +R
Sbjct: 190 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRH 249
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL 376
E + L + E + + Q+ + E L + ++ + Q+ + Q E+++L
Sbjct: 250 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL 309
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE E + + L + + VL+E D ++ L ALE+E+
Sbjct: 310 EE----ERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQ 365
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + E + +Q + L +E+ +++ E + + A+++ ++ + + ++
Sbjct: 366 EHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRE 425
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
D L E+ ++ E Q+ +L+ QLE V +L + QE R + R +
Sbjct: 426 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQL 485
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
++ +++ Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +
Sbjct: 486 QDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQ 545
Query: 616 RGETAARLHAALQAHWRHALRILA 639
R E RL A LQAHW A ++L+
Sbjct: 546 RVELVERLQAMLQAHWDEANQLLS 569
>AY160226-1|AAO22135.1| 903|Homo sapiens centrobin alpha protein.
Length = 903
Score = 111 bits (267), Expect = 8e-24
Identities = 86/384 (22%), Positives = 170/384 (44%), Gaps = 5/384 (1%)
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRA 316
L+ E +R+HCE I AVA+ DR KD I +L + R+ +R
Sbjct: 190 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRH 249
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL 376
E + L + E + + Q+ + E L + ++ + Q+ + Q E+++L
Sbjct: 250 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL 309
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE E + + L + + VL+E D ++ L ALE+E+
Sbjct: 310 EE----ERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQ 365
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + E + +Q + L +E+ +++ E + + A+++ ++ + + ++
Sbjct: 366 EHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRE 425
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
D L E+ ++ E Q+ +L+ QLE V +L + QE R + R +
Sbjct: 426 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQL 485
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
++ +++ Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +
Sbjct: 486 QDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQ 545
Query: 616 RGETAARLHAALQAHWRHALRILA 639
R E RL A LQAHW A ++L+
Sbjct: 546 RVELVERLQAMLQAHWDEANQLLS 569
>AF331638-1|AAL56068.2| 903|Homo sapiens PP1221 protein.
Length = 903
Score = 111 bits (266), Expect = 1e-23
Identities = 86/384 (22%), Positives = 170/384 (44%), Gaps = 5/384 (1%)
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRA 316
L+ E +R+HCE I AVA+ DR KD I +L + R+ +R
Sbjct: 190 LDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRH 249
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL 376
E + L + E + + Q+ + E L + ++ + Q+ + Q E+++L
Sbjct: 250 EAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETL 309
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE E + + L + + VL+E D ++ L ALE+E+
Sbjct: 310 EE----ERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQ 365
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + E + +Q + L +E+ +++ E + + A+++ ++ + + ++
Sbjct: 366 EHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRE 425
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
D L E+ ++ E Q+ +L+ QLE V +L + QE R + R +
Sbjct: 426 RDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQL 485
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
++ +++ Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +
Sbjct: 486 QDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQAQVCELQSGNQQLEEQ 545
Query: 616 RGETAARLHAALQAHWRHALRILA 639
R E RL A LQAHW A ++L+
Sbjct: 546 RVELVERLQAMLQAHWDEANQLLS 569
>BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3
(Drosophila) protein.
Length = 718
Score = 68.1 bits (159), Expect = 9e-11
Identities = 69/278 (24%), Positives = 123/278 (44%), Gaps = 21/278 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q + + E ++ DY+ +C++L+ E L +Q N EL + + EIDVL
Sbjct: 248 QTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQ-NDELTTLADEAQSLKDEIDVL 306
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+ + D V +L Q+ K LE+ + + L ++ T+ L +E
Sbjct: 307 RHSSDKVSKLEGQVESYKKKLEDL--------GDLRRQVKLLEEKNTMYMQNTVSLEEEL 358
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCH 520
K N RS+ ++Q+ E QN+ SE KK D LD E K L++ ++ LQK + +
Sbjct: 359 ----RKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLR 414
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
++ + +L+ Q Q + + L DS +I+ E + KL +
Sbjct: 415 TERDSLKETIEELRCVQAQ--EGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKL---IR 469
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ + + +KL Q EK+ LL+S ++ R+ E
Sbjct: 470 LQHENKMLKLN--QEGSDNEKIALLQSLLDDANLRKNE 505
Score = 50.8 bits (116), Expect = 1e-05
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 22/276 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID 399
D ++ EL + L + +C +L + +L+E+ ++ L N +L + + D
Sbjct: 173 DLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAE-NQVLMERLNQSD 231
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV---NDETLL 456
+++ R + QL ++ L+E + + A D + EL K I + NDE
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL--QK 514
L E LK +++ R ++ + + Q KK + L + LR+ ++L +K
Sbjct: 292 LADEAQSLKDEIDVLRHS----SDKVSKLEGQVESYKKKLEDLGD----LRRQVKLLEEK 343
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARL-KENNIVDSFNKQILRIEEQ 572
N + LE+ L K + QL+ +R+ +E RL +E+ D + + R++E
Sbjct: 344 NTMYMQNTVSLEEE-LRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKE- 401
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+++ L +K+++ ++ R L + E+L ++++
Sbjct: 402 ---KVDSL-QKEKDRLRTERDSLKETIEELRCVQAQ 433
Score = 33.5 bits (73), Expect = 2.4
Identities = 73/323 (22%), Positives = 135/323 (41%), Gaps = 42/323 (13%)
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHD-YQDKCKQLQNEKKS 375
E+ RKA ++E ++ + Q + S ES+ LD + ++K LQ EK
Sbjct: 355 EEELRKA-NAARSQLETYKRQVVELQNRLSE-ESKKADKLDFEYKRLKEKVDSLQKEKDR 412
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALE--KEKFAH 433
L + ++ + + + + +E + + +M L Q + E +EK
Sbjct: 413 LRTERDSLKETIEELRCVQAQEGQLTTQG---LMPLGSQESSDSLAAEIVTPEIREKLIR 469
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
++ + +LN+ S N++ LL D + NE + ++ Q+L E Q+Q E+
Sbjct: 470 LQHENKMLKLNQE-GSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQ 528
Query: 494 KKCDFLDNEV-------KTLRQHLELQKNELKCHYQKQ---LEDAV------LAKLQEFQ 537
K ++ K L +HLE + +E QK+ +ED K++E Q
Sbjct: 529 KSLQDQGSKAEDSVLLKKKLEEHLE-KLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQ 587
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE----EIKLYRL 593
E L + E EM+ + + + K + E+ K I L+ KQ + EI+ +
Sbjct: 588 EALRKKEEEMK--------QMEERYKKYL----EKAKSVIRTLDPKQNQGAAPEIQALKN 635
Query: 594 QLAQAAEKLGLLESKVECQRRRR 616
QL + LE + E + +R
Sbjct: 636 QLQERDRLFHSLEKEYEKTKSQR 658
>BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein.
Length = 597
Score = 68.1 bits (159), Expect = 9e-11
Identities = 69/278 (24%), Positives = 123/278 (44%), Gaps = 21/278 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q + + E ++ DY+ +C++L+ E L +Q N EL + + EIDVL
Sbjct: 248 QTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQ-NDELTTLADEAQSLKDEIDVL 306
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+ + D V +L Q+ K LE+ + + L ++ T+ L +E
Sbjct: 307 RHSSDKVSKLEGQVESYKKKLEDL--------GDLRRQVKLLEEKNTMYMQNTVSLEEEL 358
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCH 520
K N RS+ ++Q+ E QN+ SE KK D LD E K L++ ++ LQK + +
Sbjct: 359 ----RKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLR 414
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
++ + +L+ Q Q + + L DS +I+ E + KL +
Sbjct: 415 TERDSLKETIEELRCVQAQ--EGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKL---IR 469
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ + + +KL Q EK+ LL+S ++ R+ E
Sbjct: 470 LQHENKMLKLN--QEGSDNEKIALLQSLLDDANLRKNE 505
Score = 50.8 bits (116), Expect = 1e-05
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 22/276 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID 399
D ++ EL + L + +C +L + +L+E+ ++ L N +L + + D
Sbjct: 173 DLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAE-NQVLMERLNQSD 231
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV---NDETLL 456
+++ R + QL ++ L+E + + A D + EL K I + NDE
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL--QK 514
L E LK +++ R ++ + + Q KK + L + LR+ ++L +K
Sbjct: 292 LADEAQSLKDEIDVLRHS----SDKVSKLEGQVESYKKKLEDLGD----LRRQVKLLEEK 343
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARL-KENNIVDSFNKQILRIEEQ 572
N + LE+ L K + QL+ +R+ +E RL +E+ D + + R++E
Sbjct: 344 NTMYMQNTVSLEEE-LRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKE- 401
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+++ L +K+++ ++ R L + E+L ++++
Sbjct: 402 ---KVDSL-QKEKDRLRTERDSLKETIEELRCVQAQ 433
>AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated
microtubule-binding protein HOOK3 protein.
Length = 718
Score = 68.1 bits (159), Expect = 9e-11
Identities = 69/278 (24%), Positives = 123/278 (44%), Gaps = 21/278 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q + + E ++ DY+ +C++L+ E L +Q N EL + + EIDVL
Sbjct: 248 QTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQ-NDELTTLADEAQSLKDEIDVL 306
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+ + D V +L Q+ K LE+ + + L ++ T+ L +E
Sbjct: 307 RHSSDKVSKLEGQVESYKKKLEDL--------GDLRRQVKLLEEKNTMYMQNTVSLEEEL 358
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCH 520
K N RS+ ++Q+ E QN+ SE KK D LD E K L++ ++ LQK + +
Sbjct: 359 ----RKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKEKDRLR 414
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
++ + +L+ Q Q + + L DS +I+ E + KL +
Sbjct: 415 TERDSLKETIEELRCVQAQ--EGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKL---IR 469
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ + + +KL Q EK+ LL+S ++ R+ E
Sbjct: 470 LQHENKMLKLN--QEGSDNEKIALLQSLLDDANLRKNE 505
Score = 50.8 bits (116), Expect = 1e-05
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 22/276 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID 399
D ++ EL + L + +C +L + +L+E+ ++ L N +L + + D
Sbjct: 173 DLDRQLKKTTEELNEALSAKEEIAQRCHELDMQVAALQEEKSSLLAE-NQVLMERLNQSD 231
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV---NDETLL 456
+++ R + QL ++ L+E + + A D + EL K I + NDE
Sbjct: 232 SIEDPNSPAGRRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTT 291
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL--QK 514
L E LK +++ R ++ + + Q KK + L + LR+ ++L +K
Sbjct: 292 LADEAQSLKDEIDVLRHS----SDKVSKLEGQVESYKKKLEDLGD----LRRQVKLLEEK 343
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARL-KENNIVDSFNKQILRIEEQ 572
N + LE+ L K + QL+ +R+ +E RL +E+ D + + R++E
Sbjct: 344 NTMYMQNTVSLEEE-LRKANAARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKE- 401
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+++ L +K+++ ++ R L + E+L ++++
Sbjct: 402 ---KVDSL-QKEKDRLRTERDSLKETIEELRCVQAQ 433
Score = 33.5 bits (73), Expect = 2.4
Identities = 73/323 (22%), Positives = 135/323 (41%), Gaps = 42/323 (13%)
Query: 317 EDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHD-YQDKCKQLQNEKKS 375
E+ RKA ++E ++ + Q + S ES+ LD + ++K LQ EK
Sbjct: 355 EEELRKA-NAARSQLETYKRQVVELQNRLSE-ESKKADKLDFEYKRLKEKVDSLQKEKDR 412
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALE--KEKFAH 433
L + ++ + + + + +E + + +M L Q + E +EK
Sbjct: 413 LRTERDSLKETIEELRCVQAQEGQLTTQG---LMPLGSQESSDSLAAEIVTPEIREKLIR 469
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
++ + +LN+ S N++ LL D + NE + ++ Q+L E Q+Q E+
Sbjct: 470 LQHENKMLKLNQE-GSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEELQ 528
Query: 494 KKCDFLDNEV-------KTLRQHLELQKNELKCHYQKQ---LEDAV------LAKLQEFQ 537
K ++ K L +HLE + +E QK+ +ED K++E Q
Sbjct: 529 KSLQDQGSKAEDSVLLKKKLEEHLE-KLHEANNELQKKRAIIEDLEPRFNNSSLKIEELQ 587
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE----EIKLYRL 593
E L + E EM+ + + + K + E+ K I L+ KQ + EI+ +
Sbjct: 588 EALRKKEEEMK--------QMEERYKKYL----EKAKSVIRTLDPKQNQGAAPEIQALKN 635
Query: 594 QLAQAAEKLGLLESKVECQRRRR 616
QL + LE + E + +R
Sbjct: 636 QLQERDRLFHSLEKEYEKTKSQR 658
>AK057990-1|BAB71626.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ25261 fis, clone STM04691. ).
Length = 502
Score = 67.7 bits (158), Expect = 1e-10
Identities = 76/340 (22%), Positives = 160/340 (47%), Gaps = 30/340 (8%)
Query: 289 MKVDRAKDAAISKLR-EAWLRLTNSLDRAE----DRHRKALEKMICEVENFRVVADDAQK 343
+K + K A +SKL+ E L N ++ E D +K+++ + + E +++++ A K
Sbjct: 166 VKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAK 225
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
++ F + + H+ + L + LE Q+ + + + + D L+
Sbjct: 226 ESLIFGLRTERKV-WGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRI 284
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
++ T+ ++ L++ L+++ + ITE+ K Q DE + + D
Sbjct: 285 K----CKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEK---SSQLDE 337
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
+ K+ R ++QQL K+ + E+ K L+ + H K EL CH +
Sbjct: 338 VLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNR-----KWH---DKGELLCHLET 389
Query: 524 QLEDAVLAKLQEFQEQLDRAER----EMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+++ V K + +++L +AER E++ +A K +++ D+F +Q+ I E H+ EI
Sbjct: 390 QVKE-VKEKFENKEKKL-KAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQ 447
Query: 580 LEEKQREEIKLYRLQLAQAAEKL-GLLESKVECQRRRRGE 618
L ++++ I L++ Q +++ LLE C+ ++ E
Sbjct: 448 LANEKQKCIDSANLKVHQIEKEMRELLEE--TCKNKKTME 485
>AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein.
Length = 1029
Score = 67.7 bits (158), Expect = 1e-10
Identities = 76/340 (22%), Positives = 160/340 (47%), Gaps = 30/340 (8%)
Query: 289 MKVDRAKDAAISKLR-EAWLRLTNSLDRAE----DRHRKALEKMICEVENFRVVADDAQK 343
+K + K A +SKL+ E L N ++ E D +K+++ + + E +++++ A K
Sbjct: 693 VKEQKTKLAEVSKLKQETAANLQNQINTLEILIEDDKQKSIQIELLKHEKVQLISELAAK 752
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
++ F + + H+ + L + LE Q+ + + + + D L+
Sbjct: 753 ESLIFGLRTERKV-WGHELAQQGSSLAQNRGKLEAQIESLSRENECLRKTNESDSDALRI 811
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
++ T+ ++ L++ L+++ + ITE+ K Q DE + + D
Sbjct: 812 K----CKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEK---SSQLDE 864
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
+ K+ R ++QQL K+ + E+ K L+ + H K EL CH +
Sbjct: 865 VLEKLERHNERKEKLKQQLKGKEVELEEIRKAYSTLNR-----KWH---DKGELLCHLET 916
Query: 524 QLEDAVLAKLQEFQEQLDRAER----EMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+++ V K + +++L +AER E++ +A K +++ D+F +Q+ I E H+ EI
Sbjct: 917 QVKE-VKEKFENKEKKL-KAERDKSIELQKNAMEKLHSMDDAFKRQVDAIVEAHQAEIAQ 974
Query: 580 LEEKQREEIKLYRLQLAQAAEKL-GLLESKVECQRRRRGE 618
L ++++ I L++ Q +++ LLE C+ ++ E
Sbjct: 975 LANEKQKCIDSANLKVHQIEKEMRELLEE--TCKNKKTME 1012
Score = 40.3 bits (90), Expect = 0.021
Identities = 52/240 (21%), Positives = 100/240 (41%), Gaps = 14/240 (5%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
+ED ++L + + + R A+ A+ K + EL+K + D + K
Sbjct: 415 SEDNTYQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRLKE 474
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKFAH 433
+ + + VM+ EI L +M+ Q D +K+L LEK EK
Sbjct: 475 IIFRERNSKGQLEVMVHKLQNEIKKLTVE---LMKAKDQQEDHLKHL-RTLEKTLEKMER 530
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
+ ++ + IQ V + +E LL++ ++ ER + + Q L K+ + + L
Sbjct: 531 QKRQQQAAQI-RLIQEVELKASAADREIYLLRTSLHREREQAQQLHQLLALKEQEHRKEL 589
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
+ +F + E+ K E K H Q ++ + QE + L + ++EN+ R+
Sbjct: 590 ETREFFTDADFQDALAKEIAKEEKK-HEQ------MIKEYQEKIDVLSQQYMDLENEFRI 642
Score = 35.5 bits (78), Expect = 0.60
Identities = 54/226 (23%), Positives = 97/226 (42%), Gaps = 24/226 (10%)
Query: 362 YQDKCKQLQNEKKS---LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
YQ +QL E++ E+ N +D ++ + + +++ D+ T RL K++
Sbjct: 420 YQSLVEQLDQEREKRWRAEQAENKLMDYIDELHKHANEKEDIHSLALLTTDRL-KEIIFR 478
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL-LLTQERDLLKSKVNEERSRCAV 477
+N + LE H ++ I +L + D+ L R L K+ ER +
Sbjct: 479 ERNSKGQLEV--MVH-KLQNEIKKLTVELMKAKDQQEDHLKHLRTLEKTLEKMERQK--- 532
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
QQ + EV K D E+ LR L ++ + + QL + K QE +
Sbjct: 533 -RQQQAAQIRLIQEVELKASAADREIYLLRTSLHREREQAQ-----QLHQLLALKEQEHR 586
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
++L+ RE DA + D+ K+I + E++H+ I +EK
Sbjct: 587 KELET--REFFTDADFQ-----DALAKEIAKEEKKHEQMIKEYQEK 625
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 64.9 bits (151), Expect = 9e-10
Identities = 76/314 (24%), Positives = 154/314 (49%), Gaps = 26/314 (8%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESEL-YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE 383
E+M E+ N A ++EL YKT +L Q+K +++Q E+ + EQL +
Sbjct: 821 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQEL----QEKTREVQ-ERLNEMEQLKEQ 875
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT---DCVKNLEEALEKEK-----FAHDS 435
L+N + L ++E ++ E + K LT D +K L+E+L+ E+ HD+
Sbjct: 876 LENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT 935
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL-- 493
NI + +++++ + + + LKSK++EE SR +E+ E +++ + +
Sbjct: 936 VNMNI-DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVG 994
Query: 494 --KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN-D 550
KK D +TL +++ NE+ Q+++ + K E Q+ L+ E E
Sbjct: 995 IDKKQDLEAKNTQTLT--ADVKDNEI-IEQQRKIFSLIQEK-NELQQMLESVIAEKEQLK 1050
Query: 551 ARLKENNIVDSFNKQILR-IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
LKEN + N++ LR + ++ K + ++ +++ IK +L++ ++L +E K+
Sbjct: 1051 TDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK-KEGELSRTCDRLAEVEEKL 1109
Query: 610 ECQRRRRGETAARL 623
+ + ++ E +L
Sbjct: 1110 KEKSQQLQEKQQQL 1123
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/301 (20%), Positives = 145/301 (48%), Gaps = 23/301 (7%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK---KSLEEQLN 381
EKM CE+E+ + + + + E+E + + H+ ++ + + E+ +S+EE L
Sbjct: 1621 EKM-CEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLK 1679
Query: 382 TELDNVNVMLS-------NKDKEIDV----LKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
E D + L K +E+ + LKE+ +T+ +L +++ + + +
Sbjct: 1680 VERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE 1739
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
++D+ K+ ++ + ++ + + D L+ V+E+ + + +++ L +
Sbjct: 1740 HSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ 1799
Query: 491 EVLKKCDFLDNEVKTLRQHL-ELQK--NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
E +++ ++++ TL++ + E QK +E++ +KQ++D L + E L+ A++
Sbjct: 1800 EKIQELKANEHQLITLKKDVNETQKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQKLH 1858
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
EN L+E V + R+EE KLE + L+E +E K L++ Q + +L
Sbjct: 1859 EN---LEEMKSVMKERDNLRRVEETLKLERDQLKE-SLQETKARDLEIQQELKTARMLSK 1914
Query: 608 K 608
+
Sbjct: 1915 E 1915
Score = 57.6 bits (133), Expect = 1e-07
Identities = 80/366 (21%), Positives = 169/366 (46%), Gaps = 46/366 (12%)
Query: 250 DKVDIIKLEEERLK-----REHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKD---AAISK 301
D + ++E ERL+ +E E + A+ +K D+ K+ ++K
Sbjct: 1299 DSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAK 1358
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHD 361
++E+ + SL+ E + K++ E+E F+ D A + L K L +HD
Sbjct: 1359 IQESQSKQEQSLNMKEKDNETT--KIVSEMEQFKP-KDSALLRIEIEMLGLSKRLQESHD 1415
Query: 362 YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
+ +++ + L+E L +E D + K+ +++ ++ +T L K C+K
Sbjct: 1416 EMKSVAKEKDDLQRLQEVLQSESDQL------KENIKEIVAKHLETEEEL-KVAHCCLKE 1468
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
EE + + + ++ I+ + K+++++ND+ L++K+ E + E+Q
Sbjct: 1469 QEETINELRVNLSEKETEISTIQKQLEAINDK----------LQNKIQEIYEK----EEQ 1514
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
K Q SEV +K NE+K ++H + + + L+ K LE + +LQE QE++
Sbjct: 1515 FNIK--QISEVQEKV----NELKQFKEHRKAKDSALQSIESKMLE--LTNRLQESQEEIQ 1566
Query: 542 RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL-QLAQAAE 600
+E E R++E + + +++E K + ++E Q +E + ++ + + E
Sbjct: 1567 IMIKEKEEMKRVQE-----ALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1621
Query: 601 KLGLLE 606
K+ +E
Sbjct: 1622 KMCEIE 1627
Score = 54.8 bits (126), Expect = 9e-07
Identities = 62/290 (21%), Positives = 134/290 (46%), Gaps = 28/290 (9%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE---QL 380
++K I E+EN + + + H E+E + ++ ++ K + E+K L+E
Sbjct: 1133 MQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSF 1192
Query: 381 NTELDNVNVMLSNKD-------KEIDV----LKENYDTVMRLNKQLTDCVKNLEEALEKE 429
TE D++ + + +E+ + LKE+ +T+ L + +++ + + E
Sbjct: 1193 ETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLE 1252
Query: 430 KFAHDSTKSNI------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ-- 481
K +H + I EL ++ V++ + + L + ++ + A IE +
Sbjct: 1253 K-SHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1311
Query: 482 -LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ- 539
L EK + E +K + +KT+++ LE++ ++LK H ++ L A + + Q QEQ
Sbjct: 1312 RLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETL--AKIQESQSKQEQS 1369
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
L+ E++ E + E + +LRIE + L ++ ++ +E+K
Sbjct: 1370 LNMKEKDNETTKIVSEMEQFKPKDSALLRIEIE-MLGLSKRLQESHDEMK 1418
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/269 (23%), Positives = 127/269 (47%), Gaps = 18/269 (6%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
DK + + +EK + +L+N N L K +E LK N ++ L K + + K +
Sbjct: 1771 DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE---LKANEHQLITLKKDVNETQKKVS 1827
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + +K D ++T I+++N L + + +KS V +ER +E+ L
Sbjct: 1828 EMEQLKKQIKD---QSLTLSKLEIENLN-LAQKLHENLEEMKS-VMKERDNLRRVEETLK 1882
Query: 484 EKQNQCSEVLKKCDFLD----NEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
+++Q E L++ D E+KT R L + E ++++ + + ++ + Q+
Sbjct: 1883 LERDQLKESLQETKARDLEIQQELKTARM-LSKEHKETVDKLREKISEKTI-QISDIQKD 1940
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE-INVLEEKQREEIKLYRLQLAQA 598
LD+++ E++ + ++N+ V K++L +QH E + + +E +K Y ++
Sbjct: 1941 LDKSKDELQK-KQDRQNHQVKP-EKRLLSDGQQHLTESLREKCSRIKELLKRYS-EMDDH 1997
Query: 599 AEKLGLLESKVECQRRRRGETAARLHAAL 627
E L L +E + + E + R+ A L
Sbjct: 1998 YECLNRLSLDLEKEIEFQKELSMRVKANL 2026
Score = 44.0 bits (99), Expect = 0.002
Identities = 51/242 (21%), Positives = 108/242 (44%), Gaps = 20/242 (8%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID--VLKEN--YDTVMRLNKQLTDCV--- 419
K L +E + L +++ + + ++++ S KDK V KE+ + + K D
Sbjct: 730 KSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQ 789
Query: 420 ---KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K+ ++ + K H + + + + +N E + L++E S + ++ +
Sbjct: 790 SNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELS 849
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVK---TLRQHLELQKNELKCHYQKQLEDA-VLAK 532
Q+L EK + E L + + L +++ + Q +E +K + Q+ LE+ L +
Sbjct: 850 YKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQ 909
Query: 533 ----LQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLEINVLEEKQRE 586
L++ QE L ++++D N +D+ + L +QH+ IN L+ K E
Sbjct: 910 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 969
Query: 587 EI 588
E+
Sbjct: 970 EV 971
Score = 42.7 bits (96), Expect = 0.004
Identities = 57/282 (20%), Positives = 126/282 (44%), Gaps = 28/282 (9%)
Query: 312 SLDRAEDRHR--KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-- 367
+L+ A+ H + ++ ++ E +N R V + + + + L +T + Q + K
Sbjct: 1850 NLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTA 1909
Query: 368 -QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM-RLNKQ-------LTDC 418
L E K ++L ++ + +S+ K++D K+ R N Q L+D
Sbjct: 1910 RMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDG 1969
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV- 477
++L E+L ++ +E++ + +N +L L +E + K ++ ++
Sbjct: 1970 QQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLP 2029
Query: 478 -IEQQLCEK----QNQCS----EVLKKCDFLDNEVKTLR--QHLELQKNELKCHYQKQLE 526
++ + EK +CS ++KK ++ + V ++ QH + K E+ + + +
Sbjct: 2030 YLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQ 2089
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
+L K+Q Q+ D RE+ + LK N +D ++IL+
Sbjct: 2090 KELLIKIQHLQQDCDVPSRELRD---LKLNQNMDLHIEEILK 2128
Score = 38.7 bits (86), Expect = 0.065
Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDR--HRKA-LEKMICEVENFRVVADDAQKKTSHFE 349
RA K+RE L NSL A++ H+++ + KM E+E + Q K
Sbjct: 2258 RATQLTTEKIRE----LENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESN 2313
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
L KT + QDK K E L +L +++ KE + KE T
Sbjct: 2314 KCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE--KEISATKA 2371
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHD-STKSNITE---LNKRIQSVNDETLLLTQERDLLK 465
+ Q + ++ L E L + + A D S S T+ NK + ++ + +LK
Sbjct: 2372 TVEYQ-KEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILK 2430
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
S+ + ++QQ + Q +E+L L NEVKT ++
Sbjct: 2431 SEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKE 2473
Score = 38.3 bits (85), Expect = 0.085
Identities = 48/228 (21%), Positives = 103/228 (45%), Gaps = 16/228 (7%)
Query: 304 EAWLRLTNSLDRAEDRHRKALE----KMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
E L+ N LD E RK + ++ +VE R D +K + +S+ + + +
Sbjct: 530 ELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 589
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
Y + +++ K+ + T D V L K + + EN + ++ K+L
Sbjct: 590 LSYS--LESIEDPKQMKQ----TLFDAETVALDAKRESAFLRSENLELKEKM-KELATTY 642
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
K +E ++ + ++ K +L K +QS +E LT L+ KV ++ +E
Sbjct: 643 KQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLT---SLIDGKVPKDLLCNLELE 699
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
++ + Q + ++ +++ + L EV L L+ +E++ +K+++D
Sbjct: 700 GKITDLQKELNKEVEENEALREEV-ILLSELKSLPSEVE-RLRKEIQD 745
Score = 37.5 bits (83), Expect = 0.15
Identities = 63/281 (22%), Positives = 128/281 (45%), Gaps = 35/281 (12%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNV 389
E ++ + + + Q + +S+++ T+++ D Q+ QL+N +SL++ + +N
Sbjct: 910 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQE---QLRNALESLKQH----QETINT 962
Query: 390 MLSNKDKEID---VLKENY-DTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELN 444
+ S +E+ ++EN +T +++ K + EA + D + I E
Sbjct: 963 LKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ 1022
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
++I S+ E L Q +L+S + E+ ++ L E E ++ L +E+K
Sbjct: 1023 RKIFSLIQEKNELQQ---MLESVIAEKEQ----LKTDLKENIEMTIENQEELRLLGDELK 1075
Query: 505 TLRQHLELQKN-------ELK--CHYQKQLEDAVLAK---LQEFQEQLDRAEREM-ENDA 551
++ + +KN EL C ++E+ + K LQE Q+QL + EM E
Sbjct: 1076 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1135
Query: 552 RLKE-NNIVDSFNKQILRIE--EQHKLEINVLEEKQREEIK 589
++ E N+ + + L +E E +LE+ + EE+K
Sbjct: 1136 KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK 1176
Score = 33.1 bits (72), Expect = 3.2
Identities = 60/247 (24%), Positives = 104/247 (42%), Gaps = 29/247 (11%)
Query: 367 KQLQNEKKSLEE-QLNT-----ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
K++ + KK LEE L T E D + +L KD V E + + R+ +
Sbjct: 355 KEIMDLKKQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTL 414
Query: 421 NLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
E +A K + K N + + N T + T+ L + + E I+
Sbjct: 415 QQELKAKRKRRVTWCLGKINKMKNSNYADQSNIPTNITTKTHKLSINLLRE-------ID 467
Query: 480 QQLCEKQNQCSEVLKKCDFLD--NEVKTLRQ-HLELQKNELKCHYQKQLEDAVLAKLQEF 536
+ +C + + S L ++ K L Q ++E + N L+ Y + D
Sbjct: 468 ESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLD--------- 518
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQL 595
EQL R E+E E + +LKE N +D F + ++ + E++ E RE E ++ +LQ
Sbjct: 519 YEQL-RTEKE-EMELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKKLQE 576
Query: 596 AQAAEKL 602
++KL
Sbjct: 577 YIDSQKL 583
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 64.5 bits (150), Expect = 1e-09
Identities = 76/314 (24%), Positives = 154/314 (49%), Gaps = 26/314 (8%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESEL-YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE 383
E+M E+ N A ++EL YKT +L Q+K +++Q E+ + EQL +
Sbjct: 841 ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQEL----QEKTREVQ-ERLNEMEQLKEQ 895
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT---DCVKNLEEALEKEK-----FAHDS 435
L+N + L ++E ++ E + K LT D +K L+E+L+ E+ HD+
Sbjct: 896 LENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT 955
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL-- 493
NI + +++++ + + + LKSK++EE SR +E+ E +++ + +
Sbjct: 956 VNMNI-DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVG 1014
Query: 494 --KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN-D 550
KK D +TL +++ NE+ Q+++ + K E Q+ L+ E E
Sbjct: 1015 IDKKQDLEAKNTQTLT--ADVKDNEI-IEQQRKIFSLIQEK-NELQQMLESVIAEKEQLK 1070
Query: 551 ARLKENNIVDSFNKQILR-IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
LKEN + N++ LR + ++ K + ++ +++ IK +L++ ++L +E K+
Sbjct: 1071 TDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIK-KEGELSRTCDRLAEVEEKL 1129
Query: 610 ECQRRRRGETAARL 623
+ + ++ E +L
Sbjct: 1130 KEKSQQLQEKQQQL 1143
Score = 58.4 bits (135), Expect = 7e-08
Identities = 63/301 (20%), Positives = 144/301 (47%), Gaps = 23/301 (7%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK---KSLEEQLN 381
EKM CE+E+ + + + + E+E + + H+ ++ + + E+ +S+EE L
Sbjct: 1641 EKM-CEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLK 1699
Query: 382 TELDNVNVMLS-------NKDKEIDV----LKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
E D + L K +E+ + LKE+ +T+ +L +++ + + +
Sbjct: 1700 VERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE 1759
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
++D+ K+ ++ + ++ + + D L+ V+E+ + + +++ L +
Sbjct: 1760 HSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ 1819
Query: 491 EVLKKCDFLDNEVKTLRQHL-ELQK--NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
E +++ ++++ TL++ + E QK +E++ +KQ++D L + E L+ A+
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQELH 1878
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
EN L+E V + R+EE KLE + L+E +E K L++ Q + +L
Sbjct: 1879 EN---LEEMKSVMKERDNLRRVEETLKLERDQLKE-SLQETKARDLEIQQELKTARMLSK 1934
Query: 608 K 608
+
Sbjct: 1935 E 1935
Score = 57.2 bits (132), Expect = 2e-07
Identities = 80/366 (21%), Positives = 169/366 (46%), Gaps = 46/366 (12%)
Query: 250 DKVDIIKLEEERLK-----REHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKD---AAISK 301
D + ++E ERL+ +E E + A+ +K D+ K+ ++K
Sbjct: 1319 DSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAK 1378
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHD 361
++E+ + SL+ E + K++ E+E F+ D A + L K L +HD
Sbjct: 1379 IQESQSKQEQSLNMKEKDNETT--KIVSEMEQFKP-KDSALLRIEIEMLGLSKRLQESHD 1435
Query: 362 YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
+ +++ + L+E L +E D + K+ +++ ++ +T L K C+K
Sbjct: 1436 EMKSVAKEKDDLQRLQEVLQSESDQL------KENIKEIVAKHLETEEEL-KVAHCCLKE 1488
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
EE + + + ++ I+ + K+++++ND+ L++K+ E + E+Q
Sbjct: 1489 QEETINELRVNLSEKETEISTIQKQLEAINDK----------LQNKIQEIYEK----EEQ 1534
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
L K Q SEV + NE+K ++H + + + L+ K LE + +LQE QE++
Sbjct: 1535 LNIK--QISEVQENV----NELKQFKEHRKAKDSALQSIESKMLE--LTNRLQESQEEIQ 1586
Query: 542 RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL-QLAQAAE 600
+E E R++E + + +++E K + ++E Q +E + ++ + + E
Sbjct: 1587 IMIKEKEEMKRVQE-----ALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1641
Query: 601 KLGLLE 606
K+ +E
Sbjct: 1642 KMCEIE 1647
Score = 54.8 bits (126), Expect = 9e-07
Identities = 62/290 (21%), Positives = 134/290 (46%), Gaps = 28/290 (9%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE---QL 380
++K I E+EN + + + H E+E + ++ ++ K + E+K L+E
Sbjct: 1153 MQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSF 1212
Query: 381 NTELDNVNVMLSNKD-------KEIDV----LKENYDTVMRLNKQLTDCVKNLEEALEKE 429
TE D++ + + +E+ + LKE+ +T+ L + +++ + + E
Sbjct: 1213 ETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLE 1272
Query: 430 KFAHDSTKSNI------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ-- 481
K +H + I EL ++ V++ + + L + ++ + A IE +
Sbjct: 1273 K-SHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 482 -LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ- 539
L EK + E +K + +KT+++ LE++ ++LK H ++ L A + + Q QEQ
Sbjct: 1332 RLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETL--AKIQESQSKQEQS 1389
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
L+ E++ E + E + +LRIE + L ++ ++ +E+K
Sbjct: 1390 LNMKEKDNETTKIVSEMEQFKPKDSALLRIEIE-MLGLSKRLQESHDEMK 1438
Score = 48.0 bits (109), Expect = 1e-04
Identities = 55/229 (24%), Positives = 109/229 (47%), Gaps = 20/229 (8%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
DK + + +EK + +L+N N L K +E LK N ++ L K + + K +
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE---LKANEHQLITLKKDVNETQKKVS 1847
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + +K D ++T I+++N L + + +KS V +ER +E+ L
Sbjct: 1848 EMEQLKKQIKD---QSLTLSKLEIENLN-LAQELHENLEEMKS-VMKERDNLRRVEETLK 1902
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
+++Q E L++ D E+ +Q L+ + K H K+ D + K+ E Q+
Sbjct: 1903 LERDQLKESLQETKARDLEI---QQELKTARMLSKEH--KETVDKLREKISEKTIQISDI 1957
Query: 544 EREMENDARLKENNIVDSFNK--QILRIEE----QHKLEINVLEEKQRE 586
+++++ + I + K Q+LR++E HK +IN +E+ +++
Sbjct: 1958 QKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHK-KINEMEQLKKQ 2005
Score = 43.2 bits (97), Expect = 0.003
Identities = 51/242 (21%), Positives = 108/242 (44%), Gaps = 20/242 (8%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID--VLKEN--YDTVMRLNKQLTDCV--- 419
K L +E + L +++ + + ++++ S KDK V KE+ + + K D
Sbjct: 750 KSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQ 809
Query: 420 ---KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K+ ++ + K H + + + + +N E + L++E S + ++ +
Sbjct: 810 SNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELS 869
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVK---TLRQHLELQKNELKCHYQKQLEDA-VLAK 532
Q+L EK + E L + + L +++ + Q +E +K + Q+ LE+ L +
Sbjct: 870 YKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQ 929
Query: 533 ----LQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLEINVLEEKQRE 586
L++ QE L ++++D N +D+ + L +QH+ IN L+ K E
Sbjct: 930 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE 989
Query: 587 EI 588
E+
Sbjct: 990 EV 991
Score = 39.9 bits (89), Expect = 0.028
Identities = 60/302 (19%), Positives = 131/302 (43%), Gaps = 27/302 (8%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV----VADDAQK 343
+++ +A+D I + + L+ D+ R+ + + ++ + + D+ QK
Sbjct: 1911 SLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQK 1970
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT------ELDNVNVM--LSNKD 395
K + + + L + D K++ NE + L++Q E+DN + L
Sbjct: 1971 KIQELQKKELQLLRVKEDVNMSHKKI-NEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESL 2029
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+EI ++ + D + R+ + L ++ A +E A D + KR+ S + L
Sbjct: 2030 EEIRIVAKERDELRRIKESLK-MERDQFIATLREMIARDRQNHQVKP-EKRLLSDGQQHL 2087
Query: 456 L------LTQERDLLKSKVN-EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR- 507
+ ++ ++LLK ++ C EK+ + ++KK ++ + V ++
Sbjct: 2088 MESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFHRIMKKLKYVLSYVTKIKE 2147
Query: 508 -QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
QH + K E+ + + + +L K+Q Q+ D RE+ + LK N +D ++I
Sbjct: 2148 EQHECINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRD---LKLNQNMDLHIEEI 2204
Query: 567 LR 568
L+
Sbjct: 2205 LK 2206
Score = 39.5 bits (88), Expect = 0.037
Identities = 55/247 (22%), Positives = 107/247 (43%), Gaps = 29/247 (11%)
Query: 304 EAWLRLTNSLDRAEDRHRKALE----KMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
E L+ N LD E RK + ++I E+ N + + + E+EL ++L
Sbjct: 525 ELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELL 584
Query: 360 HDYQDKCKQLQ---------NEKKSLEEQLN----------TELDNVNVMLSNKDKEIDV 400
+ +D+ K+LQ N K L L T D V L K + +
Sbjct: 585 REKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFL 644
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
EN + ++ K+L K +E ++ + ++ K +L K +QS +E LT
Sbjct: 645 RSENLELKEKM-KELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLT-- 701
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
L+ KV ++ +E ++ + Q + ++ +++ + L EV L L+ +E++
Sbjct: 702 -SLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEV-ILLSELKSLPSEVE-R 758
Query: 521 YQKQLED 527
+K+++D
Sbjct: 759 LRKEIQD 765
Score = 38.7 bits (86), Expect = 0.065
Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 14/223 (6%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDR--HRKA-LEKMICEVENFRVVADDAQKKTSHFE 349
RA K+RE L NSL A++ H+++ + KM E+E + Q K
Sbjct: 2336 RATQLTTEKIRE----LENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESN 2391
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
L KT + QDK K E L +L +++ KE + KE T
Sbjct: 2392 KCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFE--KEISATKA 2449
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHD-STKSNITE---LNKRIQSVNDETLLLTQERDLLK 465
+ Q + ++ L E L + + A D S S T+ NK + ++ + +LK
Sbjct: 2450 TVEYQ-KEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILK 2508
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
S+ + ++QQ + Q +E+L L NEVKT ++
Sbjct: 2509 SEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKE 2551
Score = 37.5 bits (83), Expect = 0.15
Identities = 63/281 (22%), Positives = 128/281 (45%), Gaps = 35/281 (12%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNV 389
E ++ + + + Q + +S+++ T+++ D Q+ QL+N +SL++ + +N
Sbjct: 930 EKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQE---QLRNALESLKQH----QETINT 982
Query: 390 MLSNKDKEID---VLKENY-DTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELN 444
+ S +E+ ++EN +T +++ K + EA + D + I E
Sbjct: 983 LKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ 1042
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
++I S+ E L Q +L+S + E+ ++ L E E ++ L +E+K
Sbjct: 1043 RKIFSLIQEKNELQQ---MLESVIAEKEQ----LKTDLKENIEMTIENQEELRLLGDELK 1095
Query: 505 TLRQHLELQKN-------ELK--CHYQKQLEDAVLAK---LQEFQEQLDRAEREM-ENDA 551
++ + +KN EL C ++E+ + K LQE Q+QL + EM E
Sbjct: 1096 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1155
Query: 552 RLKE-NNIVDSFNKQILRIE--EQHKLEINVLEEKQREEIK 589
++ E N+ + + L +E E +LE+ + EE+K
Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK 1196
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 815 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 866
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 867 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 925
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 926 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 985
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 986 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 1104
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1307
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1366
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1367 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1426
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1483 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 630 H 630
+
Sbjct: 1601 Y 1601
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1736 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1793
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1794 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1851
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1852 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1909 EATE--SNEAMGREVNALKS 1926
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1584 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1637
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1638 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1697 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1752
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1753 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1859
Query: 611 CQRR 614
+R+
Sbjct: 1860 DERK 1863
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 1109 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1168
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1169 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1228
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1229 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1408 YEEKAAAYDKLEKTKNRL 1425
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 815 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 866
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 867 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 925
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 926 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 985
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 986 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 1104
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1156
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1307
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1308 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1366
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1367 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1426
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1483 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1542 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1600
Query: 630 H 630
+
Sbjct: 1601 Y 1601
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1736 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1793
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1794 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1851
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1852 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1908
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1909 EATE--SNEAMGREVNALKS 1926
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1584 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1637
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1638 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1697 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1752
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1753 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1807
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1859
Query: 611 CQRR 614
+R+
Sbjct: 1860 DERK 1863
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 1109 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1168
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1169 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1228
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1229 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1408 YEEKAAAYDKLEKTKNRL 1425
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 822 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 873
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 874 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 932
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 933 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 992
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 993 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 1111
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 1112 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1314
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1373
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1374 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1433
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1490 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 630 H 630
+
Sbjct: 1608 Y 1608
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1683 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1742
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1743 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1800
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1801 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1858
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1859 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1916 EATE--SNEAMGREVNALKS 1933
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1591 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1644
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1645 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1704 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1759
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1760 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1866
Query: 611 CQRR 614
+R+
Sbjct: 1867 DERK 1870
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 1116 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1175
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1176 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1235
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1236 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1415 YEEKAAAYDKLEKTKNRL 1432
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 822 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 873
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 874 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 932
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 933 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 992
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 993 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 1111
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 1112 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1163
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1314
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1315 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1373
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1374 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1433
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1490 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1549 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1607
Query: 630 H 630
+
Sbjct: 1608 Y 1608
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1683 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1742
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1743 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1800
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1801 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1858
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1859 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1915
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1916 EATE--SNEAMGREVNALKS 1933
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1591 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1644
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1645 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1704 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1759
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1760 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1814
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1866
Query: 611 CQRR 614
+R+
Sbjct: 1867 DERK 1870
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 1116 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1175
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1176 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1235
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1236 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1294
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1415 YEEKAAAYDKLEKTKNRL 1432
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 700 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 751
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 752 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 810
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 811 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 870
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 871 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 930
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 931 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 989
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 990 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1041
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1134 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1192
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1193 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1251
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1252 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1311
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1312 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1367
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1368 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1426
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1427 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1485
Query: 630 H 630
+
Sbjct: 1486 Y 1486
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1561 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1620
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1621 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1678
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1679 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1736
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1737 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1793
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1794 EATE--SNEAMGREVNALKS 1811
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1469 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1522
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1523 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1581
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1582 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1637
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1638 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1692
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1693 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1744
Query: 611 CQRR 614
+R+
Sbjct: 1745 DERK 1748
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 994 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1053
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1054 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1113
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1114 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1172
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1173 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1232
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1233 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1292
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1293 YEEKAAAYDKLEKTKNRL 1310
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 64.1 bits (149), Expect = 2e-09
Identities = 84/352 (23%), Positives = 162/352 (46%), Gaps = 39/352 (11%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQK--- 343
AMKV + AA KLR W RL + K L ++ + E + D+ QK
Sbjct: 827 AMKVIQRNCAAYLKLRNWQWWRLFTKV--------KPLLQVTRQEEEMQAKEDELQKTKE 878
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV--- 400
+ E+EL K L+ H + K L E+ E +L E + + V L+ K +E++
Sbjct: 879 RQQKAENEL-KELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 937
Query: 401 -----LKENYDTVMRLN---KQLTDCVKNLEEALEKEKFAHD-------STKSNITELNK 445
L+E D +L K++ + +LEE LE+E+ A + ++ I +L
Sbjct: 938 EMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLED 997
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNE 502
I ++D+ L++ER LL+ ++++ + A E++ L + +N+ ++ + + +
Sbjct: 998 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1057
Query: 503 VKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
+ RQ LE K +L+ + +Q+ D + A++ E + QL + E E++ ++ I
Sbjct: 1058 EEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIA 1116
Query: 560 DSFNK-QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
N + +R E H ++ + +R Q E+L L++++E
Sbjct: 1117 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 1168
Score = 46.4 bits (105), Expect = 3e-04
Identities = 77/361 (21%), Positives = 159/361 (44%), Gaps = 28/361 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+V+ K ++++E + ++ +RA + K+ EVE+ + ++A+ K
Sbjct: 1261 EVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLA 1319
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-V 408
++ D Q+ ++ +K ++ +L + N + D+E++ K+N + +
Sbjct: 1320 KDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA-KQNLERHI 1378
Query: 409 MRLNKQLTDCVKNLE------EALEKEKFAHDSTKSNITELNKRIQSVNDE----TLLLT 458
LN QL+D K L+ EALE+ K N+T+ + + D+ L
Sbjct: 1379 STLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ 1438
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
QE D L ++ +R + +E +KQ + ++L + + ++ R E + E +
Sbjct: 1439 QELDDLVVDLDNQRQLVSNLE----KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1494
Query: 519 ---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN---NIVD-SFNKQILRIE- 570
+ LE+A+ AK +E + + EME+ K++ N+ + +K+ L +
Sbjct: 1495 TKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1553
Query: 571 EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E+ K ++ LE E Q E RL++ A K G E ++ + + E +L L
Sbjct: 1554 EEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQFERDLQARDEQNEEKRRQLQRQLHE 1612
Query: 630 H 630
+
Sbjct: 1613 Y 1613
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 1688 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1747
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 1748 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 1805
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 1806 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 1863
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 1864 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 1920
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 1921 EATE--SNEAMGREVNALKS 1938
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/304 (20%), Positives = 128/304 (42%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 1596 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 1649
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + +L + + + +E++ + + D + K+ K+LE L + E
Sbjct: 1650 KGREEAIK-QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1708
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 1709 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 1764
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 1765 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 1819
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 1820 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 1871
Query: 611 CQRR 614
+R+
Sbjct: 1872 DERK 1875
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/318 (19%), Positives = 137/318 (43%), Gaps = 16/318 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKK 344
A+K R + IS L+E + ++AE + R + LE + E+E+ Q+
Sbjct: 1121 ALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQEL 1180
Query: 345 TSHFESE---LYKTLDL-AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ E E L K LD ++ + ++++ + E+L +L+ +N DK
Sbjct: 1181 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 1240
Query: 401 L-KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L KEN D L + L + +E +K + +S ++ + +ND+ L
Sbjct: 1241 LEKENADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1299
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQ---CSEVLKKCDFLDNEVKTLRQHLELQKNE 516
E + + +NE + + + + +Q E+L++ V T + LE ++N
Sbjct: 1300 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1359
Query: 517 LKCHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQ 572
L+ +++E + + QL +++++++ A E F K+I + +Q
Sbjct: 1360 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1419
Query: 573 HKLEINVLEEKQREEIKL 590
++ + ++ ++ + +L
Sbjct: 1420 YEEKAAAYDKLEKTKNRL 1437
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 63.7 bits (148), Expect = 2e-09
Identities = 78/344 (22%), Positives = 152/344 (44%), Gaps = 40/344 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNV----NVMLSNKDKE 397
Q++ E+ L + + ++++C L +EK++L+EQL+ L + ++ ++ K K
Sbjct: 285 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 344
Query: 398 IDVLKENYDTVMRLNKQ----LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
I L++ + + +L + + + + + E LE ++ I +L RI+ +
Sbjct: 345 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKE-------EEIAQLRSRIKQMT-- 395
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT-------- 505
TQ +L + K ER+ +E+ L Q K +D ++KT
Sbjct: 396 ----TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 451
Query: 506 ---LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE-QLDRAEREMENDARLKENNIVDS 561
L+Q L K E+ +K E+ + AKLQ+ E +L R E+E+ + +E +
Sbjct: 452 RISLQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 562 FNKQILRIEEQHKLEINVLEEKQR----EEIKLYRLQ-LAQAAEKLGLLESKVECQRRRR 616
K L + L+I+ +E+Q EE++L + L ++ KL L+ + E R R
Sbjct: 511 M-KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569
Query: 617 GETAARLHAALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEHK 660
E + L +LQ + + + + H+ V +HK
Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHK 613
Score = 62.1 bits (144), Expect = 6e-09
Identities = 77/373 (20%), Positives = 163/373 (43%), Gaps = 20/373 (5%)
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAW-LR 308
+ ++ + L +E LK + E ++++ K+AAIS LR+ +
Sbjct: 1350 ENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS---EKEAAISSLRKQYDEE 1406
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ 368
LD+ +D K ++ + E + DD K S ++ + H K Q
Sbjct: 1407 KCELLDQVQDLSFK-VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFT-QHQNTVKELQ 1464
Query: 369 LQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLK-ENYDTVMRLNKQLTDCVKNLEEAL 426
+Q E KS E + + +++ + L ++K D LK E D ++ K+ + NLE L
Sbjct: 1465 IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKES----NLETEL 1520
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ + + +IT+ I+S+N+ Q++D+ ++ ++ + + EK
Sbjct: 1521 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKD 1577
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
N+ E +K L+N+V +++ LE +K EL+ H ++ +L+ +++L+
Sbjct: 1578 NRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKSKE-EELKALEDRLESESAA 1635
Query: 547 MENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ + K + + KQ+L E+ + + E E+ +L + ++ +LE
Sbjct: 1636 KLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL---NTKLQEREREVHILE 1692
Query: 607 SKVECQRRRRGET 619
K++ + ET
Sbjct: 1693 EKLKSVESSQSET 1705
Score = 56.0 bits (129), Expect = 4e-07
Identities = 67/325 (20%), Positives = 148/325 (45%), Gaps = 30/325 (9%)
Query: 310 TNSLDRAEDRHRKALEKMI--CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
T L + +++ +EK+ CE E ++ D +H E KTL+ Q + +
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 687
Query: 368 QLQNE-------KKSLEEQLNTELDNVNVMLSNKDKEID------------VLKENYDTV 408
L +E + LEE+L+ D + M + ++D ++KE+ ++
Sbjct: 688 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 747
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
R K L D + L E L KE+ H ++++ L I+ E + + D+ +S
Sbjct: 748 QRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 806
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ + E+QL + Q + ++ + L +V + + EL H + Q++D
Sbjct: 807 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH-KIQVQD 865
Query: 528 AVLAKLQEFQEQLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++ +L++ ++++ + + +++L++ N KQIL +E+++ I + E Q+
Sbjct: 866 -LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENM--ILQMREGQK 921
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
+EI++ +L+ + + +L + E
Sbjct: 922 KEIEILTQKLSAKEDSIHILNEEYE 946
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/344 (20%), Positives = 155/344 (45%), Gaps = 31/344 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ + R + A ++ + L L D+ H+ +E + +++ A K F
Sbjct: 745 VSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 803
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLK-EN 404
+S T + Y+++ QLQ + LE + L ++ V + E+D K +
Sbjct: 804 QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 863
Query: 405 YDTVMRLNKQLTDC---VKNL----EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
D + +L KQ ++ VK+L E LE + TK + E I + +
Sbjct: 864 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ--- 920
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
+E ++L K++ + ++ + E + + KK + + + K +++ L+ + +
Sbjct: 921 KKEIEILTQKLSAKEDSIHILNE---EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 977
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREM--ENDARLKE--NNIVDSFNKQILRIEEQH 573
+ +K+LE+ L +L + ++Q + EM N A + + + + + +QI + E H
Sbjct: 978 EAKLKKELENTAL-ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 574 KLEIN----VLEEK---QREEI-KLYRLQLAQAAEKLGLLESKV 609
+ E+N + E+K Q EE+ +++ +QL + +++ L+ K+
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1080
Score = 51.6 bits (118), Expect = 9e-06
Identities = 59/292 (20%), Positives = 140/292 (47%), Gaps = 33/292 (11%)
Query: 322 KALEKMICEVENFRVVADDAQKKT-SHF-ESELYKTLDLAH-DYQDKCKQLQNEKKSLEE 378
+AL++M + ++ ++ ++K+ SH + +L ++ H D + K + EK+ L +
Sbjct: 1885 QALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGK 1944
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
++ ++ ++ +E+++LK+ YD ++ + +K +E LE + H+ST
Sbjct: 1945 EIVRLQKDLRMLRKEHQQELEILKKEYD------QEREEKIKQEQEDLELK---HNST-- 1993
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK-QNQCSEVLKKCD 497
L + ++ N + L Q+ L+ + E ++ +E +L E Q + +++LKK
Sbjct: 1994 ----LKQLMREFNTQ---LAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIA 2046
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN 557
D+++K + E E+ + AK+++ Q QL+ +++ + +EN
Sbjct: 2047 EKDDDLKRTAKRYE--------EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENP 2098
Query: 558 IVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
D N I+ ++ Q + ++ + + +E + +R Q+ ++L E V
Sbjct: 2099 GND--NVTIMELQTQLAQKTTLISDSKLKE-QEFREQIHNLEDRLKKYEKNV 2147
Score = 48.8 bits (111), Expect = 6e-05
Identities = 56/320 (17%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKT----SHFESELYKTLDLAHD----YQD 364
L++ +D H K+I ++ + + + + ++ + + ++++TL++ + +
Sbjct: 330 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS 389
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
+ KQ+ + + L EQ + +K + ++ + +L ++ + +K +E+
Sbjct: 390 RIKQMTTQGEELREQKEK---SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 425 ALEKEKFAHDS----TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E+E+ + K + ++ K+ L E++L + K E + E+
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 505
Query: 481 QLCEK-----QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED------AV 529
+ E+ + SE LK + + + LELQK + + +L D
Sbjct: 506 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILRIEEQHKLEINVLEEKQ-- 584
++ E + L+++ +E +N ++ ++ + NK+I + E+HK E+ L+ +Q
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 585 --REEIKLYRLQLAQAAEKL 602
E++++ + Q EKL
Sbjct: 626 LWTEKLQVLKQQYQTEMEKL 645
Score = 48.0 bits (109), Expect = 1e-04
Identities = 61/278 (21%), Positives = 127/278 (45%), Gaps = 36/278 (12%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEID 399
+K HF+ + + + ++K L+N+ S++ +L T EL++VN+ + +K++E+
Sbjct: 1564 QKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1623
Query: 400 VLKENYDT--------VMRLNKQLTDCVKN--LEEALEKEKFAHDSTKSNITELNKRIQS 449
L++ ++ + R +Q +K L + EKE+ T+S+++ELN ++Q
Sbjct: 1624 ALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1683
Query: 450 VNDETLLLTQERDLLKSKVNEE-------RSRCAVIEQQLCEKQNQCSEVLK-KCDFLDN 501
E +L ++ ++S +E ++ A EQ+ + Q + + K L
Sbjct: 1684 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR 1743
Query: 502 ---EVKTLRQHLELQKNE-------LKCHYQKQL--EDAVLAKLQEFQEQLDRAEREMEN 549
E + L Q + +K E ++C YQ++L + AK E Q + + E+E
Sbjct: 1744 NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1803
Query: 550 DARLKENNIVDSFNKQ--ILRIEEQHKLEINVLEEKQR 585
+ + K+ I+ + LE NV ++ Q+
Sbjct: 1804 KNKKYSLIVAQHVEKEGGKNNIQAKQNLE-NVFDDVQK 1840
Score = 42.7 bits (96), Expect = 0.004
Identities = 53/287 (18%), Positives = 134/287 (46%), Gaps = 16/287 (5%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K H E++ ++ + Q++ ++ +N+K SL + E + + K +V +
Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1837
Query: 404 NYDTVMR--LNKQLTDC-VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
T+ L Q+ + +K L+ L ++K H +T +++Q++ +
Sbjct: 1838 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR-NKP 1896
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
+LL+ EE+S+ +++ +L Q +++ K + E + L + + + +L+
Sbjct: 1897 TELLEENT-EEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRM 1955
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN----IVDSFNKQILRIEEQHKL 575
++ ++ + K + QE+ ++ ++E E D LK N+ ++ FN Q+ + E++ ++
Sbjct: 1956 LRKEHQQELEILKKEYDQEREEKIKQEQE-DLELKHNSTLKQLMREFNTQLAQKEQELEM 2014
Query: 576 ----EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
IN +E + E ++ ++ + Q +K+ + ++ +R E
Sbjct: 2015 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/259 (22%), Positives = 110/259 (42%), Gaps = 35/259 (13%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLE 423
++ +N+ KS++ + + + + + E + +L K+L++ V ++
Sbjct: 1300 EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMK 1359
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSV------------------NDETLLLTQERDLLK 465
E L+++K S +T+LN ++Q+ ++ LL Q +DL
Sbjct: 1360 EELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1419
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL----DNEVKTLRQHLELQKNELKCHY 521
+ + + +E Q+ + N+ SE KK N VK L+ LEL+ E Y
Sbjct: 1420 KVDTLSKEKISALE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEA---Y 1475
Query: 522 QKQLEDAVL-AKLQEFQEQLDRAEREMEND---ARLKENNIVDSFNKQILRIE--EQHKL 575
+K + +L +L + ++ D + EME+D KE+N+ Q RI E H
Sbjct: 1476 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHIT 1535
Query: 576 EINVLEEKQREEIKLYRLQ 594
+ + E E +K Y Q
Sbjct: 1536 QKTIEIESLNEVLKNYNQQ 1554
Score = 37.9 bits (84), Expect = 0.11
Identities = 40/192 (20%), Positives = 85/192 (44%), Gaps = 6/192 (3%)
Query: 373 KKSLEEQLNTELDNVN-VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+K L +Q EL ++ + L K++E+ LK+ +++ + L+E K+
Sbjct: 1048 EKKLNQQAE-ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDT 1106
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + + + + S+ + L + L+ +N+ +++QL E + E
Sbjct: 1107 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1166
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKL-QEFQEQLDRAEREME 548
+K L +++KT + + K+ + K LED L KL +E QLD ++ E
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1225
Query: 549 NDARLKENNIVD 560
K N +++
Sbjct: 1226 ALLEAKTNELIN 1237
Score = 37.5 bits (83), Expect = 0.15
Identities = 50/265 (18%), Positives = 113/265 (42%), Gaps = 12/265 (4%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
K+L + +++ + Q KK L+E+ + L+ + +S ++ +LK+ +R
Sbjct: 184 KSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQR----LRNGP 239
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
D +K L + LE + A TK E + V D T + T E L+ +V + +
Sbjct: 240 MNVDVLKPLPQ-LEPQ--AEVFTKEENPESDGE-PVVEDGTSVKTLE--TLQQRVKRQEN 293
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
++ + + QC+ + + + L ++ Q LE K+ K + L
Sbjct: 294 LLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQ--LRDA 351
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+ EQL++ + + + + + + ++ ++I ++ + K EE + ++ K R
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA 411
Query: 594 QLAQAAEKLGLLESKVECQRRRRGE 618
+ + L + E +R+ + E
Sbjct: 412 AFEELEKALSTAQKTEEARRKLKAE 436
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 63.7 bits (148), Expect = 2e-09
Identities = 78/344 (22%), Positives = 152/344 (44%), Gaps = 40/344 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNV----NVMLSNKDKE 397
Q++ E+ L + + ++++C L +EK++L+EQL+ L + ++ ++ K K
Sbjct: 285 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 344
Query: 398 IDVLKENYDTVMRLNKQ----LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
I L++ + + +L + + + + + E LE ++ I +L RI+ +
Sbjct: 345 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKE-------EEIAQLRSRIKQMT-- 395
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT-------- 505
TQ +L + K ER+ +E+ L Q K +D ++KT
Sbjct: 396 ----TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 451
Query: 506 ---LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE-QLDRAEREMENDARLKENNIVDS 561
L+Q L K E+ +K E+ + AKLQ+ E +L R E+E+ + +E +
Sbjct: 452 RISLQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELTKKLQTREREFQEQ 510
Query: 562 FNKQILRIEEQHKLEINVLEEKQR----EEIKLYRLQ-LAQAAEKLGLLESKVECQRRRR 616
K L + L+I+ +E+Q EE++L + L ++ KL L+ + E R R
Sbjct: 511 M-KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 569
Query: 617 GETAARLHAALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEHK 660
E + L +LQ + + + + H+ V +HK
Sbjct: 570 LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHK 613
Score = 62.1 bits (144), Expect = 6e-09
Identities = 77/373 (20%), Positives = 163/373 (43%), Gaps = 20/373 (5%)
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAW-LR 308
+ ++ + L +E LK + E ++++ K+AAIS LR+ +
Sbjct: 1350 ENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS---EKEAAISSLRKQYDEE 1406
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ 368
LD+ +D K ++ + E + DD K S ++ + H K Q
Sbjct: 1407 KCELLDQVQDLSFK-VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFT-QHQNTVKELQ 1464
Query: 369 LQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLK-ENYDTVMRLNKQLTDCVKNLEEAL 426
+Q E KS E + + +++ + L ++K D LK E D ++ K+ + NLE L
Sbjct: 1465 IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKES----NLETEL 1520
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ + + +IT+ I+S+N+ Q++D+ ++ ++ + + EK
Sbjct: 1521 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKD 1577
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
N+ E +K L+N+V +++ LE +K EL+ H ++ +L+ +++L+
Sbjct: 1578 NRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKSKE-EELKALEDRLESESAA 1635
Query: 547 MENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ + K + + KQ+L E+ + + E E+ +L + ++ +LE
Sbjct: 1636 KLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL---NTKLQEREREVHILE 1692
Query: 607 SKVECQRRRRGET 619
K++ + ET
Sbjct: 1693 EKLKSVESSQSET 1705
Score = 56.0 bits (129), Expect = 4e-07
Identities = 67/325 (20%), Positives = 148/325 (45%), Gaps = 30/325 (9%)
Query: 310 TNSLDRAEDRHRKALEKMI--CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
T L + +++ +EK+ CE E ++ D +H E KTL+ Q + +
Sbjct: 628 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 687
Query: 368 QLQNE-------KKSLEEQLNTELDNVNVMLSNKDKEID------------VLKENYDTV 408
L +E + LEE+L+ D + M + ++D ++KE+ ++
Sbjct: 688 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 747
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
R K L D + L E L KE+ H ++++ L I+ E + + D+ +S
Sbjct: 748 QRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 806
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ + E+QL + Q + ++ + L +V + + EL H + Q++D
Sbjct: 807 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH-KIQVQD 865
Query: 528 AVLAKLQEFQEQLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++ +L++ ++++ + + +++L++ N KQIL +E+++ I + E Q+
Sbjct: 866 -LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENM--ILQMREGQK 921
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
+EI++ +L+ + + +L + E
Sbjct: 922 KEIEILTQKLSAKEDSIHILNEEYE 946
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/344 (20%), Positives = 155/344 (45%), Gaps = 31/344 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ + R + A ++ + L L D+ H+ +E + +++ A K F
Sbjct: 745 VSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 803
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLK-EN 404
+S T + Y+++ QLQ + LE + L ++ V + E+D K +
Sbjct: 804 QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 863
Query: 405 YDTVMRLNKQLTDC---VKNL----EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
D + +L KQ ++ VK+L E LE + TK + E I + +
Sbjct: 864 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ--- 920
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
+E ++L K++ + ++ + E + + KK + + + K +++ L+ + +
Sbjct: 921 KKEIEILTQKLSAKEDSIHILNE---EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 977
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREM--ENDARLKE--NNIVDSFNKQILRIEEQH 573
+ +K+LE+ L +L + ++Q + EM N A + + + + + +QI + E H
Sbjct: 978 EAKLKKELENTAL-ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 574 KLEIN----VLEEK---QREEI-KLYRLQLAQAAEKLGLLESKV 609
+ E+N + E+K Q EE+ +++ +QL + +++ L+ K+
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1080
Score = 51.6 bits (118), Expect = 9e-06
Identities = 59/292 (20%), Positives = 140/292 (47%), Gaps = 33/292 (11%)
Query: 322 KALEKMICEVENFRVVADDAQKKT-SHF-ESELYKTLDLAH-DYQDKCKQLQNEKKSLEE 378
+AL++M + ++ ++ ++K+ SH + +L ++ H D + K + EK+ L +
Sbjct: 1885 QALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGK 1944
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
++ ++ ++ +E+++LK+ YD ++ + +K +E LE + H+ST
Sbjct: 1945 EIVRLQKDLRMLRKEHQQELEILKKEYD------QEREEKIKQEQEDLELK---HNST-- 1993
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK-QNQCSEVLKKCD 497
L + ++ N + L Q+ L+ + E ++ +E +L E Q + +++LKK
Sbjct: 1994 ----LKQLMREFNTQ---LAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIA 2046
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN 557
D+++K + E E+ + AK+++ Q QL+ +++ + +EN
Sbjct: 2047 EKDDDLKRTAKRYE--------EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENP 2098
Query: 558 IVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
D N I+ ++ Q + ++ + + +E + +R Q+ ++L E V
Sbjct: 2099 GND--NVTIMELQTQLAQKTTLISDSKLKE-QEFREQIHNLEDRLKKYEKNV 2147
Score = 48.8 bits (111), Expect = 6e-05
Identities = 56/320 (17%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKT----SHFESELYKTLDLAHD----YQD 364
L++ +D H K+I ++ + + + + ++ + + ++++TL++ + +
Sbjct: 330 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS 389
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
+ KQ+ + + L EQ + +K + ++ + +L ++ + +K +E+
Sbjct: 390 RIKQMTTQGEELREQKEK---SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 446
Query: 425 ALEKEKFAHDS----TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E+E+ + K + ++ K+ L E++L + K E + E+
Sbjct: 447 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 505
Query: 481 QLCEK-----QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED------AV 529
+ E+ + SE LK + + + LELQK + + +L D
Sbjct: 506 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 565
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILRIEEQHKLEINVLEEKQ-- 584
++ E + L+++ +E +N ++ ++ + NK+I + E+HK E+ L+ +Q
Sbjct: 566 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 625
Query: 585 --REEIKLYRLQLAQAAEKL 602
E++++ + Q EKL
Sbjct: 626 LWTEKLQVLKQQYQTEMEKL 645
Score = 48.0 bits (109), Expect = 1e-04
Identities = 61/278 (21%), Positives = 127/278 (45%), Gaps = 36/278 (12%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEID 399
+K HF+ + + + ++K L+N+ S++ +L T EL++VN+ + +K++E+
Sbjct: 1564 QKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1623
Query: 400 VLKENYDT--------VMRLNKQLTDCVKN--LEEALEKEKFAHDSTKSNITELNKRIQS 449
L++ ++ + R +Q +K L + EKE+ T+S+++ELN ++Q
Sbjct: 1624 ALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1683
Query: 450 VNDETLLLTQERDLLKSKVNEE-------RSRCAVIEQQLCEKQNQCSEVLK-KCDFLDN 501
E +L ++ ++S +E ++ A EQ+ + Q + + K L
Sbjct: 1684 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR 1743
Query: 502 ---EVKTLRQHLELQKNE-------LKCHYQKQL--EDAVLAKLQEFQEQLDRAEREMEN 549
E + L Q + +K E ++C YQ++L + AK E Q + + E+E
Sbjct: 1744 NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1803
Query: 550 DARLKENNIVDSFNKQ--ILRIEEQHKLEINVLEEKQR 585
+ + K+ I+ + LE NV ++ Q+
Sbjct: 1804 KNKKYSLIVAQHVEKEGGKNNIQAKQNLE-NVFDDVQK 1840
Score = 42.7 bits (96), Expect = 0.004
Identities = 53/287 (18%), Positives = 134/287 (46%), Gaps = 16/287 (5%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K H E++ ++ + Q++ ++ +N+K SL + E + + K +V +
Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1837
Query: 404 NYDTVMR--LNKQLTDC-VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
T+ L Q+ + +K L+ L ++K H +T +++Q++ +
Sbjct: 1838 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR-NKP 1896
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
+LL+ EE+S+ +++ +L Q +++ K + E + L + + + +L+
Sbjct: 1897 TELLEENT-EEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRM 1955
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN----IVDSFNKQILRIEEQHKL 575
++ ++ + K + QE+ ++ ++E E D LK N+ ++ FN Q+ + E++ ++
Sbjct: 1956 LRKEHQQELEILKKEYDQEREEKIKQEQE-DLELKHNSTLKQLMREFNTQLAQKEQELEM 2014
Query: 576 ----EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
IN +E + E ++ ++ + Q +K+ + ++ +R E
Sbjct: 2015 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/259 (22%), Positives = 110/259 (42%), Gaps = 35/259 (13%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLE 423
++ +N+ KS++ + + + + + E + +L K+L++ V ++
Sbjct: 1300 EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMK 1359
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSV------------------NDETLLLTQERDLLK 465
E L+++K S +T+LN ++Q+ ++ LL Q +DL
Sbjct: 1360 EELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1419
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL----DNEVKTLRQHLELQKNELKCHY 521
+ + + +E Q+ + N+ SE KK N VK L+ LEL+ E Y
Sbjct: 1420 KVDTLSKEKISALE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEA---Y 1475
Query: 522 QKQLEDAVL-AKLQEFQEQLDRAEREMEND---ARLKENNIVDSFNKQILRIE--EQHKL 575
+K + +L +L + ++ D + EME+D KE+N+ Q RI E H
Sbjct: 1476 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHIT 1535
Query: 576 EINVLEEKQREEIKLYRLQ 594
+ + E E +K Y Q
Sbjct: 1536 QKTIEIESLNEVLKNYNQQ 1554
Score = 37.9 bits (84), Expect = 0.11
Identities = 40/192 (20%), Positives = 85/192 (44%), Gaps = 6/192 (3%)
Query: 373 KKSLEEQLNTELDNVN-VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+K L +Q EL ++ + L K++E+ LK+ +++ + L+E K+
Sbjct: 1048 EKKLNQQAE-ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDT 1106
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + + + + S+ + L + L+ +N+ +++QL E + E
Sbjct: 1107 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1166
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKL-QEFQEQLDRAEREME 548
+K L +++KT + + K+ + K LED L KL +E QLD ++ E
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1225
Query: 549 NDARLKENNIVD 560
K N +++
Sbjct: 1226 ALLEAKTNELIN 1237
Score = 37.5 bits (83), Expect = 0.15
Identities = 50/265 (18%), Positives = 113/265 (42%), Gaps = 12/265 (4%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
K+L + +++ + Q KK L+E+ + L+ + +S ++ +LK+ +R
Sbjct: 184 KSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQR----LRNGP 239
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
D +K L + LE + A TK E + V D T + T E L+ +V + +
Sbjct: 240 MNVDVLKPLPQ-LEPQ--AEVFTKEENPESDGE-PVVEDGTSVKTLE--TLQQRVKRQEN 293
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
++ + + QC+ + + + L ++ Q LE K+ K + L
Sbjct: 294 LLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQ--LRDA 351
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+ EQL++ + + + + + + ++ ++I ++ + K EE + ++ K R
Sbjct: 352 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA 411
Query: 594 QLAQAAEKLGLLESKVECQRRRRGE 618
+ + L + E +R+ + E
Sbjct: 412 AFEELEKALSTAQKTEEARRKLKAE 436
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 63.7 bits (148), Expect = 2e-09
Identities = 78/344 (22%), Positives = 152/344 (44%), Gaps = 40/344 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNV----NVMLSNKDKE 397
Q++ E+ L + + ++++C L +EK++L+EQL+ L + ++ ++ K K
Sbjct: 140 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 199
Query: 398 IDVLKENYDTVMRLNKQ----LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
I L++ + + +L + + + + + E LE ++ I +L RI+ +
Sbjct: 200 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKE-------EEIAQLRSRIKQMT-- 250
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT-------- 505
TQ +L + K ER+ +E+ L Q K +D ++KT
Sbjct: 251 ----TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 306
Query: 506 ---LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE-QLDRAEREMENDARLKENNIVDS 561
L+Q L K E+ +K E+ + AKLQ+ E +L R E+E+ + +E +
Sbjct: 307 RISLQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELTKKLQTREREFQEQ 365
Query: 562 FNKQILRIEEQHKLEINVLEEKQR----EEIKLYRLQ-LAQAAEKLGLLESKVECQRRRR 616
K L + L+I+ +E+Q EE++L + L ++ KL L+ + E R R
Sbjct: 366 M-KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 424
Query: 617 GETAARLHAALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEHK 660
E + L +LQ + + + + H+ V +HK
Sbjct: 425 LELESSLEKSLQENENQSKDLAVHLEAEKNKHNKEITVMVEKHK 468
Score = 62.1 bits (144), Expect = 6e-09
Identities = 77/373 (20%), Positives = 163/373 (43%), Gaps = 20/373 (5%)
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAW-LR 308
+ ++ + L +E LK + E ++++ K+AAIS LR+ +
Sbjct: 1205 ENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLS---EKEAAISSLRKQYDEE 1261
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ 368
LD+ +D K ++ + E + DD K S ++ + H K Q
Sbjct: 1262 KCELLDQVQDLSFK-VDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFT-QHQNTVKELQ 1319
Query: 369 LQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLK-ENYDTVMRLNKQLTDCVKNLEEAL 426
+Q E KS E + + +++ + L ++K D LK E D ++ K+ + NLE L
Sbjct: 1320 IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKES----NLETEL 1375
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ + + +IT+ I+S+N+ Q++D+ ++ ++ + + EK
Sbjct: 1376 KSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKD 1432
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
N+ E +K L+N+V +++ LE +K EL+ H ++ +L+ +++L+
Sbjct: 1433 NRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKSKE-EELKALEDRLESESAA 1490
Query: 547 MENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ + K + + KQ+L E+ + + E E+ +L + ++ +LE
Sbjct: 1491 KLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL---NTKLQEREREVHILE 1547
Query: 607 SKVECQRRRRGET 619
K++ + ET
Sbjct: 1548 EKLKSVESSQSET 1560
Score = 54.0 bits (124), Expect = 2e-06
Identities = 65/318 (20%), Positives = 146/318 (45%), Gaps = 30/318 (9%)
Query: 317 EDRHRKALEKMI--CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE-- 372
+ +++ +EK+ CE E ++ D +H E KTL+ Q + + L +E
Sbjct: 490 KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELS 549
Query: 373 -----KKSLEEQLNTELDNVNVMLSNKDKEID------------VLKENYDTVMRLNKQL 415
+ LEE+L+ D + M + ++D ++KE+ ++ R K L
Sbjct: 550 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 609
Query: 416 TDCVKNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
D + L E L KE+ H ++++ L I+ E + + D+ +S + +
Sbjct: 610 KDQINQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 668
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
E+QL + Q + ++ + L +V + + EL H + Q++D ++ +L+
Sbjct: 669 TKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH-KIQVQD-LMQQLE 726
Query: 535 EFQEQLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
+ ++++ + + +++L++ N KQIL +E+++ I + E Q++EI++
Sbjct: 727 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENM--ILQMREGQKKEIEILT 783
Query: 593 LQLAQAAEKLGLLESKVE 610
+L+ + + +L + E
Sbjct: 784 QKLSAKEDSIHILNEEYE 801
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/344 (20%), Positives = 155/344 (45%), Gaps = 31/344 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ + R + A ++ + L L D+ H+ +E + +++ A K F
Sbjct: 600 VSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 658
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLK-EN 404
+S T + Y+++ QLQ + LE + L ++ V + E+D K +
Sbjct: 659 QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 718
Query: 405 YDTVMRLNKQLTDC---VKNL----EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
D + +L KQ ++ VK+L E LE + TK + E I + +
Sbjct: 719 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ--- 775
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
+E ++L K++ + ++ + E + + KK + + + K +++ L+ + +
Sbjct: 776 KKEIEILTQKLSAKEDSIHILNE---EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 832
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREM--ENDARLKE--NNIVDSFNKQILRIEEQH 573
+ +K+LE+ L +L + ++Q + EM N A + + + + + +QI + E H
Sbjct: 833 EAKLKKELENTAL-ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 891
Query: 574 KLEIN----VLEEK---QREEI-KLYRLQLAQAAEKLGLLESKV 609
+ E+N + E+K Q EE+ +++ +QL + +++ L+ K+
Sbjct: 892 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 935
Score = 52.0 bits (119), Expect = 6e-06
Identities = 58/320 (18%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKT----SHFESELYKTLDLAHD----YQD 364
L++ +D H K+I ++ + + + + ++ + + ++++TL++ + +
Sbjct: 185 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS 244
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
+ KQ+ + + L EQ + +K + ++ + +L ++ + +K +E+
Sbjct: 245 RIKQMTTQGEELREQKEK---SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 301
Query: 425 ALEKEKFAHDS----TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E+E+ + K + ++ K+ L E++L + K E + E+
Sbjct: 302 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 360
Query: 481 QLCEK-----QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED------AV 529
+ E+ + SE LK + + + LELQK + + +L D
Sbjct: 361 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 420
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILRIEEQHKLEINVLEEKQ-- 584
++ E + L+++ +E EN ++ ++ + NK+I + E+HK E+ L+ +Q
Sbjct: 421 RTRILELESSLEKSLQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 480
Query: 585 --REEIKLYRLQLAQAAEKL 602
EE+++ + Q EKL
Sbjct: 481 LWAEELQVLKQQYQTEMEKL 500
Score = 51.6 bits (118), Expect = 9e-06
Identities = 59/292 (20%), Positives = 140/292 (47%), Gaps = 33/292 (11%)
Query: 322 KALEKMICEVENFRVVADDAQKKT-SHF-ESELYKTLDLAH-DYQDKCKQLQNEKKSLEE 378
+AL++M + ++ ++ ++K+ SH + +L ++ H D + K + EK+ L +
Sbjct: 1740 QALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGK 1799
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
++ ++ ++ +E+++LK+ YD ++ + +K +E LE + H+ST
Sbjct: 1800 EIVRLQKDLRMLRKEHQQELEILKKEYD------QEREEKIKQEQEDLELK---HNST-- 1848
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK-QNQCSEVLKKCD 497
L + ++ N + L Q+ L+ + E ++ +E +L E Q + +++LKK
Sbjct: 1849 ----LKQLMREFNTQ---LAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIA 1901
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN 557
D+++K + E E+ + AK+++ Q QL+ +++ + +EN
Sbjct: 1902 EKDDDLKRTAKRYE--------EILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENP 1953
Query: 558 IVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
D N I+ ++ Q + ++ + + +E + +R Q+ ++L E V
Sbjct: 1954 GND--NVTIMELQTQLAQKTTLISDSKLKE-QEFREQIHNLEDRLKKYEKNV 2002
Score = 48.0 bits (109), Expect = 1e-04
Identities = 61/278 (21%), Positives = 127/278 (45%), Gaps = 36/278 (12%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEID 399
+K HF+ + + + ++K L+N+ S++ +L T EL++VN+ + +K++E+
Sbjct: 1419 QKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1478
Query: 400 VLKENYDT--------VMRLNKQLTDCVKN--LEEALEKEKFAHDSTKSNITELNKRIQS 449
L++ ++ + R +Q +K L + EKE+ T+S+++ELN ++Q
Sbjct: 1479 ALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1538
Query: 450 VNDETLLLTQERDLLKSKVNEE-------RSRCAVIEQQLCEKQNQCSEVLK-KCDFLDN 501
E +L ++ ++S +E ++ A EQ+ + Q + + K L
Sbjct: 1539 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR 1598
Query: 502 ---EVKTLRQHLELQKNE-------LKCHYQKQL--EDAVLAKLQEFQEQLDRAEREMEN 549
E + L Q + +K E ++C YQ++L + AK E Q + + E+E
Sbjct: 1599 NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1658
Query: 550 DARLKENNIVDSFNKQ--ILRIEEQHKLEINVLEEKQR 585
+ + K+ I+ + LE NV ++ Q+
Sbjct: 1659 KNKKYSLIVAQHVEKEGGKNNIQAKQNLE-NVFDDVQK 1695
Score = 45.2 bits (102), Expect = 7e-04
Identities = 69/320 (21%), Positives = 139/320 (43%), Gaps = 26/320 (8%)
Query: 303 REAWLRLTNSLDRAEDRHRKALEKMICEV-ENFRVVADDAQKKTSHFESELYKTLDLAHD 361
R A+ L +L A+ + +A K+ E+ E + + ++++ + EL + D
Sbjct: 265 RAAFEELEKALSTAQ-KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVD 323
Query: 362 YQDKCKQLQNEK--KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
K + Q K K E++L + + L +++E + + L K ++ +
Sbjct: 324 VMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK-----VALEKSQSEYL 378
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL--LTQERDLLKSKVNEERSRCAV 477
K +E ++E A + EL K+ E L L QE + ++++ E S
Sbjct: 379 KISQEKEQQESLALEEL-----ELQKKAILTESENKLRDLQQEAETYRTRILELESS--- 430
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEV-KTLRQHLELQKNELKC--HYQKQLEDAVLAKL- 533
+E+ L E +NQ ++ + N+ K + +E K EL+ H Q L L L
Sbjct: 431 LEKSLQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLK 490
Query: 534 QEFQEQLD--RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQREEIKL 590
Q++Q +++ R + E E + LK+ I+ + + + + KL++N E E E+
Sbjct: 491 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVNQTELESLSSELSE 550
Query: 591 YRLQLAQAAEKLGLLESKVE 610
+ E+L +L+ + +
Sbjct: 551 VLKARHKLEEELSVLKDQTD 570
Score = 42.7 bits (96), Expect = 0.004
Identities = 53/287 (18%), Positives = 134/287 (46%), Gaps = 16/287 (5%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K H E++ ++ + Q++ ++ +N+K SL + E + + K +V +
Sbjct: 1634 KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1692
Query: 404 NYDTVMR--LNKQLTDC-VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
T+ L Q+ + +K L+ L ++K H +T +++Q++ +
Sbjct: 1693 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR-NKP 1751
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
+LL+ EE+S+ +++ +L Q +++ K + E + L + + + +L+
Sbjct: 1752 TELLEENT-EEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRM 1810
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN----IVDSFNKQILRIEEQHKL 575
++ ++ + K + QE+ ++ ++E E D LK N+ ++ FN Q+ + E++ ++
Sbjct: 1811 LRKEHQQELEILKKEYDQEREEKIKQEQE-DLELKHNSTLKQLMREFNTQLAQKEQELEM 1869
Query: 576 ----EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
IN +E + E ++ ++ + Q +K+ + ++ +R E
Sbjct: 1870 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 1916
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/259 (22%), Positives = 110/259 (42%), Gaps = 35/259 (13%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLE 423
++ +N+ KS++ + + + + + E + +L K+L++ V ++
Sbjct: 1155 EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMK 1214
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSV------------------NDETLLLTQERDLLK 465
E L+++K S +T+LN ++Q+ ++ LL Q +DL
Sbjct: 1215 EELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF 1274
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL----DNEVKTLRQHLELQKNELKCHY 521
+ + + +E Q+ + N+ SE KK N VK L+ LEL+ E Y
Sbjct: 1275 KVDTLSKEKISALE-QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEA---Y 1330
Query: 522 QKQLEDAVL-AKLQEFQEQLDRAEREMEND---ARLKENNIVDSFNKQILRIE--EQHKL 575
+K + +L +L + ++ D + EME+D KE+N+ Q RI E H
Sbjct: 1331 EKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHIT 1390
Query: 576 EINVLEEKQREEIKLYRLQ 594
+ + E E +K Y Q
Sbjct: 1391 QKTIEIESLNEVLKNYNQQ 1409
Score = 37.9 bits (84), Expect = 0.11
Identities = 40/192 (20%), Positives = 85/192 (44%), Gaps = 6/192 (3%)
Query: 373 KKSLEEQLNTELDNVN-VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+K L +Q EL ++ + L K++E+ LK+ +++ + L+E K+
Sbjct: 903 EKKLNQQAE-ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDT 961
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + + + + S+ + L + L+ +N+ +++QL E + E
Sbjct: 962 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1021
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKL-QEFQEQLDRAEREME 548
+K L +++KT + + K+ + K LED L KL +E QLD ++ E
Sbjct: 1022 DKRKVSELTSKLKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1080
Query: 549 NDARLKENNIVD 560
K N +++
Sbjct: 1081 ALLEAKTNELIN 1092
Score = 35.1 bits (77), Expect = 0.80
Identities = 49/265 (18%), Positives = 112/265 (42%), Gaps = 12/265 (4%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
K+L + +++ + Q KK L+E+ + L+ + +S ++ +LK+ +R
Sbjct: 39 KSLRKIAELREELQMDQQAKKHLQEEFDASLEEKDQHISVLQTQVSLLKQR----LRNGP 94
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
D +K L + LE + A TK E + V D + T E L+ +V + +
Sbjct: 95 MNVDVLKPLPQ-LEPQ--AEVFTKEENPESDGE-PVVEDGASVKTLE--TLQQRVKRQEN 148
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
++ + + QC+ + + + L ++ Q LE K+ K + L
Sbjct: 149 LLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQ--LRDA 206
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+ EQL++ + + + + + + ++ ++I ++ + K EE + ++ K R
Sbjct: 207 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA 266
Query: 594 QLAQAAEKLGLLESKVECQRRRRGE 618
+ + L + E +R+ + E
Sbjct: 267 AFEELEKALSTAQKTEEARRKLKAE 291
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 63.7 bits (148), Expect = 2e-09
Identities = 85/339 (25%), Positives = 153/339 (45%), Gaps = 39/339 (11%)
Query: 308 RLTNSLDRAEDRHRKAL---EKMICEVENFRVVADDAQ-----KKTSHFESELYKTL--- 356
++ N L A+DRH +A+ EKM + ++ D+A+ KK EL K L
Sbjct: 1281 QIRNQLQEAQDRHTEAVRCAEKM--QDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNA 1338
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L+ D +++ K+L K+SLE L+ E+ NV L ++EI K ++++ +
Sbjct: 1339 NLSEDEKEQLKKLMELKQSLECNLDQEMKK-NVEL---EREITGFKN----LLKMTR--- 1387
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K L E E H K++ E++ +I + + LT E + SK ++
Sbjct: 1388 ---KKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1444
Query: 477 VIEQQLCEK---QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC--HYQKQLEDA--- 528
+++++L Q +C ++ K L+ EV LR H+E EL Y++++E+
Sbjct: 1445 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1504
Query: 529 -VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE--EQHKLEINVLEEK-Q 584
+ KL+E L EN + +ENN ++ LRI+ E +I +E
Sbjct: 1505 EIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFN 1564
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
+ E++ Y+ + + L SK+ R E +L
Sbjct: 1565 KTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKL 1603
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/298 (19%), Positives = 133/298 (44%), Gaps = 15/298 (5%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL + ++ D ++ LE++ ++ + + ++K + + ++ K +
Sbjct: 1087 SKLNSLEIEFHHTRDALREK-TLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQ 1145
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
+++ QLQ+E L +Q LD+ + NK+K + +++ + +++ + ++
Sbjct: 1146 ESVEERLSQLQSENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQ 1201
Query: 420 KNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQE-RDLLKSKVNEERSRCAV 477
L E KE + + K + L QE D LK + E S V
Sbjct: 1202 SLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEAS-LEV 1260
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQ-E 535
+ +++ ++ KK + N+++ + +H E + K KQ + AKL+
Sbjct: 1261 TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVT 1320
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE-QHKLEINVLEEKQREEIKLYR 592
++Q+D+ E +N L N+ + +Q+ ++ E + LE N L+++ ++ ++L R
Sbjct: 1321 VKKQMDKIEELQKN---LLNANLSEDEKEQLKKLMELKQSLECN-LDQEMKKNVELER 1374
Score = 36.3 bits (80), Expect = 0.34
Identities = 56/274 (20%), Positives = 124/274 (45%), Gaps = 25/274 (9%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS 346
+ +K+ + +D RE L T + + + E+ +C + R + ++K
Sbjct: 765 LTVKIKKMEDKVNVLQRE--LSETKEIKSQLEHQKVEWERELCSL---RFSLNQEEEKRR 819
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
+ ++ K + +++ ++ K+ LE L T + + SN ++ V++E D
Sbjct: 820 NADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQ---VVQERND 876
Query: 407 TVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVN----DETLLLTQERD 462
+L+++ + L++ + H S + I K++ S N +E L+ +
Sbjct: 877 AQRQLSREQN--ARMLQDGILTN---HLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNS 931
Query: 463 LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV-KTLRQHLELQKNELKCHY 521
+L+ ++ R I+ Q EK+ +C E LK + ++ KT++Q+ E + Y
Sbjct: 932 MLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-QY 990
Query: 522 QKQL-----EDAVL-AKLQEFQEQLDRAEREMEN 549
+L E+A+L +KL+ ++ +R E E+E+
Sbjct: 991 NGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1024
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 63.7 bits (148), Expect = 2e-09
Identities = 85/339 (25%), Positives = 153/339 (45%), Gaps = 39/339 (11%)
Query: 308 RLTNSLDRAEDRHRKAL---EKMICEVENFRVVADDAQ-----KKTSHFESELYKTL--- 356
++ N L A+DRH +A+ EKM + ++ D+A+ KK EL K L
Sbjct: 1265 QIRNQLQEAQDRHTEAVRCAEKM--QDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNA 1322
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L+ D +++ K+L K+SLE L+ E+ NV L ++EI K ++++ +
Sbjct: 1323 NLSEDEKEQLKKLMELKQSLECNLDQEMKK-NVEL---EREITGFKN----LLKMTR--- 1371
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K L E E H K++ E++ +I + + LT E + SK ++
Sbjct: 1372 ---KKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1428
Query: 477 VIEQQLCEK---QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC--HYQKQLEDA--- 528
+++++L Q +C ++ K L+ EV LR H+E EL Y++++E+
Sbjct: 1429 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1488
Query: 529 -VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE--EQHKLEINVLEEK-Q 584
+ KL+E L EN + +ENN ++ LRI+ E +I +E
Sbjct: 1489 EIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFN 1548
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
+ E++ Y+ + + L SK+ R E +L
Sbjct: 1549 KTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKL 1587
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/298 (19%), Positives = 133/298 (44%), Gaps = 15/298 (5%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL + ++ D ++ LE++ ++ + + ++K + + ++ K +
Sbjct: 1071 SKLNSLEIEFHHTRDALREK-TLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQ 1129
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
+++ QLQ+E L +Q LD+ + NK+K + +++ + +++ + ++
Sbjct: 1130 ESVEERLSQLQSENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQ 1185
Query: 420 KNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQE-RDLLKSKVNEERSRCAV 477
L E KE + + K + L QE D LK + E S V
Sbjct: 1186 SLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEAS-LEV 1244
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQ-E 535
+ +++ ++ KK + N+++ + +H E + K KQ + AKL+
Sbjct: 1245 TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVT 1304
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE-QHKLEINVLEEKQREEIKLYR 592
++Q+D+ E +N L N+ + +Q+ ++ E + LE N L+++ ++ ++L R
Sbjct: 1305 VKKQMDKIEELQKN---LLNANLSEDEKEQLKKLMELKQSLECN-LDQEMKKNVELER 1358
Score = 36.3 bits (80), Expect = 0.34
Identities = 56/274 (20%), Positives = 124/274 (45%), Gaps = 25/274 (9%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS 346
+ +K+ + +D RE L T + + + E+ +C + R + ++K
Sbjct: 749 LTVKIKKMEDKVNVLQRE--LSETKEIKSQLEHQKVEWERELCSL---RFSLNQEEEKRR 803
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
+ ++ K + +++ ++ K+ LE L T + + SN ++ V++E D
Sbjct: 804 NADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQ---VVQERND 860
Query: 407 TVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVN----DETLLLTQERD 462
+L+++ + L++ + H S + I K++ S N +E L+ +
Sbjct: 861 AQRQLSREQN--ARMLQDGILTN---HLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNS 915
Query: 463 LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV-KTLRQHLELQKNELKCHY 521
+L+ ++ R I+ Q EK+ +C E LK + ++ KT++Q+ E + Y
Sbjct: 916 MLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-QY 974
Query: 522 QKQL-----EDAVL-AKLQEFQEQLDRAEREMEN 549
+L E+A+L +KL+ ++ +R E E+E+
Sbjct: 975 NGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1008
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 63.7 bits (148), Expect = 2e-09
Identities = 78/344 (22%), Positives = 152/344 (44%), Gaps = 40/344 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNV----NVMLSNKDKE 397
Q++ E+ L + + ++++C L +EK++L+EQL+ L + ++ ++ K K
Sbjct: 316 QQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 375
Query: 398 IDVLKENYDTVMRLNKQ----LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
I L++ + + +L + + + + + E LE ++ I +L RI+ +
Sbjct: 376 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKE-------EEIAQLRSRIKQMT-- 426
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT-------- 505
TQ +L + K ER+ +E+ L Q K +D ++KT
Sbjct: 427 ----TQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 482
Query: 506 ---LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE-QLDRAEREMENDARLKENNIVDS 561
L+Q L K E+ +K E+ + AKLQ+ E +L R E+E+ + +E +
Sbjct: 483 RISLQQELSRVKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELTKKLQTREREFQEQ 541
Query: 562 FNKQILRIEEQHKLEINVLEEKQR----EEIKLYRLQ-LAQAAEKLGLLESKVECQRRRR 616
K L + L+I+ +E+Q EE++L + L ++ KL L+ + E R R
Sbjct: 542 M-KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRI 600
Query: 617 GETAARLHAALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEHK 660
E + L +LQ + + + + H+ V +HK
Sbjct: 601 LELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHK 644
Score = 56.0 bits (129), Expect = 4e-07
Identities = 67/325 (20%), Positives = 148/325 (45%), Gaps = 30/325 (9%)
Query: 310 TNSLDRAEDRHRKALEKMI--CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
T L + +++ +EK+ CE E ++ D +H E KTL+ Q + +
Sbjct: 659 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 718
Query: 368 QLQNE-------KKSLEEQLNTELDNVNVMLSNKDKEID------------VLKENYDTV 408
L +E + LEE+L+ D + M + ++D ++KE+ ++
Sbjct: 719 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 778
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
R K L D + L E L KE+ H ++++ L I+ E + + D+ +S
Sbjct: 779 QRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 837
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ + E+QL + Q + ++ + L +V + + EL H + Q++D
Sbjct: 838 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH-KIQVQD 896
Query: 528 AVLAKLQEFQEQLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++ +L++ ++++ + + +++L++ N KQIL +E+++ I + E Q+
Sbjct: 897 -LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENM--ILQMREGQK 952
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
+EI++ +L+ + + +L + E
Sbjct: 953 KEIEILTQKLSAKEDSIHILNEEYE 977
Score = 53.6 bits (123), Expect = 2e-06
Identities = 70/344 (20%), Positives = 155/344 (45%), Gaps = 31/344 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ + R + A ++ + L L D+ H+ +E + +++ A K F
Sbjct: 776 VSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 834
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLK-EN 404
+S T + Y+++ QLQ + LE + L ++ V + E+D K +
Sbjct: 835 QSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQV 894
Query: 405 YDTVMRLNKQLTDC---VKNL----EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
D + +L KQ ++ VK+L E LE + TK + E I + +
Sbjct: 895 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQ--- 951
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
+E ++L K++ + ++ + E + + KK + + + K +++ L+ + +
Sbjct: 952 KKEIEILTQKLSAKEDSIHILNE---EYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 1008
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREM--ENDARLKE--NNIVDSFNKQILRIEEQH 573
+ +K+LE+ L +L + ++Q + EM N A + + + + + +QI + E H
Sbjct: 1009 EAKLKKELENTAL-ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1067
Query: 574 KLEIN----VLEEK---QREEI-KLYRLQLAQAAEKLGLLESKV 609
+ E+N + E+K Q EE+ +++ +QL + +++ L+ K+
Sbjct: 1068 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI 1111
Score = 48.8 bits (111), Expect = 6e-05
Identities = 56/320 (17%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKT----SHFESELYKTLDLAHD----YQD 364
L++ +D H K+I ++ + + + + ++ + + ++++TL++ + +
Sbjct: 361 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRS 420
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
+ KQ+ + + L EQ + +K + ++ + +L ++ + +K +E+
Sbjct: 421 RIKQMTTQGEELREQKEK---SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 477
Query: 425 ALEKEKFAHDS----TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E+E+ + K + ++ K+ L E++L + K E + E+
Sbjct: 478 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR-KEQELTKKLQTRER 536
Query: 481 QLCEK-----QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED------AV 529
+ E+ + SE LK + + + LELQK + + +L D
Sbjct: 537 EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 596
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILRIEEQHKLEINVLEEKQ-- 584
++ E + L+++ +E +N ++ ++ + NK+I + E+HK E+ L+ +Q
Sbjct: 597 RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 656
Query: 585 --REEIKLYRLQLAQAAEKL 602
E++++ + Q EKL
Sbjct: 657 LWTEKLQVLKQQYQTEMEKL 676
Score = 37.9 bits (84), Expect = 0.11
Identities = 40/192 (20%), Positives = 85/192 (44%), Gaps = 6/192 (3%)
Query: 373 KKSLEEQLNTELDNVN-VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+K L +Q EL ++ + L K++E+ LK+ +++ + L+E K+
Sbjct: 1079 EKKLNQQAE-ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDT 1137
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + + + + S+ + L + L+ +N+ +++QL E + E
Sbjct: 1138 TLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1197
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKL-QEFQEQLDRAEREME 548
+K L +++KT + + K+ + K LED L KL +E QLD ++ E
Sbjct: 1198 DKRKVSELTSKLKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1256
Query: 549 NDARLKENNIVD 560
K N +++
Sbjct: 1257 ALLEAKTNELIN 1268
Score = 37.5 bits (83), Expect = 0.15
Identities = 50/265 (18%), Positives = 113/265 (42%), Gaps = 12/265 (4%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
K+L + +++ + Q KK L+E+ + L+ + +S ++ +LK+ +R
Sbjct: 215 KSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQR----LRNGP 270
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
D +K L + LE + A TK E + V D T + T E L+ +V + +
Sbjct: 271 MNVDVLKPLPQ-LEPQ--AEVFTKEENPESDGE-PVVEDGTSVKTLE--TLQQRVKRQEN 324
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
++ + + QC+ + + + L ++ Q LE K+ K + L
Sbjct: 325 LLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQ--LRDA 382
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+ EQL++ + + + + + + ++ ++I ++ + K EE + ++ K R
Sbjct: 383 KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERA 442
Query: 594 QLAQAAEKLGLLESKVECQRRRRGE 618
+ + L + E +R+ + E
Sbjct: 443 AFEELEKALSTAQKTEEARRKLKAE 467
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 63.7 bits (148), Expect = 2e-09
Identities = 85/339 (25%), Positives = 153/339 (45%), Gaps = 39/339 (11%)
Query: 308 RLTNSLDRAEDRHRKAL---EKMICEVENFRVVADDAQ-----KKTSHFESELYKTL--- 356
++ N L A+DRH +A+ EKM + ++ D+A+ KK EL K L
Sbjct: 1270 QIRNQLQEAQDRHTEAVRCAEKM--QDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNA 1327
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L+ D +++ K+L K+SLE L+ E+ NV L ++EI K ++++ +
Sbjct: 1328 NLSEDEKEQLKKLMELKQSLECNLDQEMKK-NVEL---EREITGFKN----LLKMTR--- 1376
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K L E E H K++ E++ +I + + LT E + SK ++
Sbjct: 1377 ---KKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1433
Query: 477 VIEQQLCEK---QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC--HYQKQLEDA--- 528
+++++L Q +C ++ K L+ EV LR H+E EL Y++++E+
Sbjct: 1434 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1493
Query: 529 -VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE--EQHKLEINVLEEK-Q 584
+ KL+E L EN + +ENN ++ LRI+ E +I +E
Sbjct: 1494 EIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFN 1553
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
+ E++ Y+ + + L SK+ R E +L
Sbjct: 1554 KTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKL 1592
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/298 (19%), Positives = 133/298 (44%), Gaps = 15/298 (5%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL + ++ D ++ LE++ ++ + + ++K + + ++ K +
Sbjct: 1076 SKLNSLEIEFHHTRDALREK-TLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQ 1134
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
+++ QLQ+E L +Q LD+ + NK+K + +++ + +++ + ++
Sbjct: 1135 ESVEERLSQLQSENMLLRQQ----LDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQ 1190
Query: 420 KNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQE-RDLLKSKVNEERSRCAV 477
L E KE + + K + L QE D LK + E S V
Sbjct: 1191 SLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEAS-LEV 1249
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQ-E 535
+ +++ ++ KK + N+++ + +H E + K KQ + AKL+
Sbjct: 1250 TSRYRINLEDETQDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVT 1309
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE-QHKLEINVLEEKQREEIKLYR 592
++Q+D+ E +N L N+ + +Q+ ++ E + LE N L+++ ++ ++L R
Sbjct: 1310 VKKQMDKIEELQKN---LLNANLSEDEKEQLKKLMELKQSLECN-LDQEMKKNVELER 1363
Score = 36.3 bits (80), Expect = 0.34
Identities = 56/274 (20%), Positives = 124/274 (45%), Gaps = 25/274 (9%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS 346
+ +K+ + +D RE L T + + + E+ +C + R + ++K
Sbjct: 754 LTVKIKKMEDKVNVLQRE--LSETKEIKSQLEHQKVEWERELCSL---RFSLNQEEEKRR 808
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
+ ++ K + +++ ++ K+ LE L T + + SN ++ V++E D
Sbjct: 809 NADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELRTVKSNLNQ---VVQERND 865
Query: 407 TVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVN----DETLLLTQERD 462
+L+++ + L++ + H S + I K++ S N +E L+ +
Sbjct: 866 AQRQLSREQN--ARMLQDGILTN---HLSKQKEIEMAQKKMNSENSHSHEEEKDLSHKNS 920
Query: 463 LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV-KTLRQHLELQKNELKCHY 521
+L+ ++ R I+ Q EK+ +C E LK + ++ KT++Q+ E + Y
Sbjct: 921 MLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-QY 979
Query: 522 QKQL-----EDAVL-AKLQEFQEQLDRAEREMEN 549
+L E+A+L +KL+ ++ +R E E+E+
Sbjct: 980 NGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1013
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 62.5 bits (145), Expect = 5e-09
Identities = 72/307 (23%), Positives = 146/307 (47%), Gaps = 27/307 (8%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-L 352
A+ I E + RL DR + + L K + E+E R+ + QK+T + E +
Sbjct: 251 AEHFTIELTEENFRRLQAEHDR-QAKELFLLRKTLEEME-LRI---ETQKQTLNARDESI 305
Query: 353 YKTLDLAHDYQDKCKQLQ--NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
K L++ K L+ NE+ + +++ ++ V+L K+KE L+E +
Sbjct: 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQ 365
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-------L 463
L + K L+ +E + S + NI +L IQ + +L T++R+ +
Sbjct: 366 LQPEPAK-TKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEV 424
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KS +++ ++Q+L +K+++ + K + L N+ +QH+E+ K L Q+
Sbjct: 425 YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQR 484
Query: 524 ----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLE 576
Q E DA+ +L+E + L++ ++++ D ++ + K +L ++E+ +
Sbjct: 485 AAILQTEVDALRLRLEEKESFLNKKTKQLQ-DLTEEKGTLAGEIRDMKDMLEVKER---K 540
Query: 577 INVLEEK 583
INVL++K
Sbjct: 541 INVLQKK 547
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/337 (19%), Positives = 150/337 (44%), Gaps = 22/337 (6%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D A++ L EA ++R +++ + + + E+E+FR D ++K + ++EL +
Sbjct: 580 DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEK 639
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK------ENYDTVM 409
D ++ L S + +++L ++ + + K +E L+ N +
Sbjct: 640 ESSLIDLKEHASSL----ASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDS 695
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV----NDETLLLTQERDLLK 465
R+N + D +K L++ + ++ + L + ++ V ND+ + + L
Sbjct: 696 RMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTL 755
Query: 466 SKVNEERSRCAVIE--QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
+ ++ + A ++ QQL +K+N +++L++ ++ + QHL++++ +
Sbjct: 756 RHMKDQNKKVANLKHNQQLEKKKN--AQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 813
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVL 580
Q DA A+L Q+ L E + N + R + I++ + +L + I +L
Sbjct: 814 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALL 873
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLL-ESKVECQRRRR 616
E ++ K +A EK L+ + K + Q R +
Sbjct: 874 ELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 910
Score = 49.2 bits (112), Expect = 5e-05
Identities = 68/271 (25%), Positives = 128/271 (47%), Gaps = 22/271 (8%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ KQ ++K+S L T+L+ ++ S+ + I+VLKE+ + L V L
Sbjct: 437 DQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR 496
Query: 424 EAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
L EKE F + T K++Q + +E L E +K + + + V+++++
Sbjct: 497 LRLEEKESFLNKKT--------KQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI 548
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
Q Q + K+ L + VK+L+ L LE+A L++ + E+L +
Sbjct: 549 ENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL-----ATLEEA-LSEKERIIERL-K 601
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ-HKLEINVLE-EKQREEIKLYRLQLAQAAE 600
+RE ++ RL+E ++SF K+ ++E+ + L+ + E E ++K + LA A
Sbjct: 602 EQRERDDRERLEE---IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL 658
Query: 601 KLGLLESKVECQRRRRGETAARLHAAL-QAH 630
K +E ++ E ++L A L +AH
Sbjct: 659 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/299 (24%), Positives = 131/299 (43%), Gaps = 39/299 (13%)
Query: 354 KTLDLAHDYQDKCKQLQNEK---KSLE---EQLNTELDNVNVMLSNKDKEIDVLKEN--- 404
K +L +DK KQL N K KSL+ +T L + LS K++ I+ LKE
Sbjct: 547 KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Query: 405 --------YDTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
++ + NK L + V L+ E EKE S++ +L + S+ L
Sbjct: 607 DDRERLEEIESFRKENKDLKEKVNALQAELTEKE--------SSLIDLKEHASSLASAGL 658
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
+ L+ + +++ C+ +E QL + N + +F D ++K L + ++
Sbjct: 659 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFAD-QIKQLDKEASYYRD 717
Query: 516 ELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
E C + D +L L+E + + + ++++ L ++ D NK++ ++ +L
Sbjct: 718 E--CGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQ-NKKVANLKHNQQL 774
Query: 576 E----INVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E +LEE ++RE+ Q Q E + LE R+ T ARL + Q+
Sbjct: 775 EKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEK----TRQELDATKARLASTQQS 829
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 62.5 bits (145), Expect = 5e-09
Identities = 72/307 (23%), Positives = 146/307 (47%), Gaps = 27/307 (8%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-L 352
A+ I E + RL DR + + L K + E+E R+ + QK+T + E +
Sbjct: 251 AEHFTIELTEENFRRLQAEHDR-QAKELFLLRKTLEEME-LRI---ETQKQTLNARDESI 305
Query: 353 YKTLDLAHDYQDKCKQLQ--NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
K L++ K L+ NE+ + +++ ++ V+L K+KE L+E +
Sbjct: 306 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQ 365
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-------L 463
L + K L+ +E + S + NI +L IQ + +L T++R+ +
Sbjct: 366 LQPEPAK-TKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEV 424
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KS +++ ++Q+L +K+++ + K + L N+ +QH+E+ K L Q+
Sbjct: 425 YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQR 484
Query: 524 ----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLE 576
Q E DA+ +L+E + L++ ++++ D ++ + K +L ++E+ +
Sbjct: 485 AAILQTEVDALRLRLEEKESFLNKKTKQLQ-DLTEEKGTLAGEIRDMKDMLEVKER---K 540
Query: 577 INVLEEK 583
INVL++K
Sbjct: 541 INVLQKK 547
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/337 (19%), Positives = 150/337 (44%), Gaps = 22/337 (6%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D A++ L EA ++R +++ + + + E+E+FR D ++K + ++EL +
Sbjct: 580 DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEK 639
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK------ENYDTVM 409
D ++ L S + +++L ++ + + K +E L+ N +
Sbjct: 640 ESSLIDLKEHASSL----ASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDS 695
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV----NDETLLLTQERDLLK 465
R+N + D +K L++ + ++ + L + ++ V ND+ + + L
Sbjct: 696 RMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTL 755
Query: 466 SKVNEERSRCAVIE--QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
+ ++ + A ++ QQL +K+N +++L++ ++ + QHL++++ +
Sbjct: 756 RHMKDQNKKVANLKHNQQLEKKKN--AQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 813
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVL 580
Q DA A+L Q+ L E + N + R + I++ + +L + I +L
Sbjct: 814 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALL 873
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLL-ESKVECQRRRR 616
E ++ K +A EK L+ + K + Q R +
Sbjct: 874 ELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 910
Score = 49.2 bits (112), Expect = 5e-05
Identities = 68/271 (25%), Positives = 128/271 (47%), Gaps = 22/271 (8%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ KQ ++K+S L T+L+ ++ S+ + I+VLKE+ + L V L
Sbjct: 437 DQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR 496
Query: 424 EAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
L EKE F + T K++Q + +E L E +K + + + V+++++
Sbjct: 497 LRLEEKESFLNKKT--------KQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI 548
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
Q Q + K+ L + VK+L+ L LE+A L++ + E+L +
Sbjct: 549 ENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL-----ATLEEA-LSEKERIIERL-K 601
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ-HKLEINVLE-EKQREEIKLYRLQLAQAAE 600
+RE ++ RL+E ++SF K+ ++E+ + L+ + E E ++K + LA A
Sbjct: 602 EQRERDDRERLEE---IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL 658
Query: 601 KLGLLESKVECQRRRRGETAARLHAAL-QAH 630
K +E ++ E ++L A L +AH
Sbjct: 659 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 689
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/299 (24%), Positives = 131/299 (43%), Gaps = 39/299 (13%)
Query: 354 KTLDLAHDYQDKCKQLQNEK---KSLE---EQLNTELDNVNVMLSNKDKEIDVLKEN--- 404
K +L +DK KQL N K KSL+ +T L + LS K++ I+ LKE
Sbjct: 547 KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 606
Query: 405 --------YDTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
++ + NK L + V L+ E EKE S++ +L + S+ L
Sbjct: 607 DDRERLEEIESFRKENKDLKEKVNALQAELTEKE--------SSLIDLKEHASSLASAGL 658
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
+ L+ + +++ C+ +E QL + N + +F D ++K L + ++
Sbjct: 659 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFAD-QIKQLDKEASYYRD 717
Query: 516 ELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
E C + D +L L+E + + + ++++ L ++ D NK++ ++ +L
Sbjct: 718 E--CGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQ-NKKVANLKHNQQL 774
Query: 576 E----INVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E +LEE ++RE+ Q Q E + LE R+ T ARL + Q+
Sbjct: 775 EKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEK----TRQELDATKARLASTQQS 829
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 62.5 bits (145), Expect = 5e-09
Identities = 72/307 (23%), Positives = 146/307 (47%), Gaps = 27/307 (8%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-L 352
A+ I E + RL DR + + L K + E+E R+ + QK+T + E +
Sbjct: 264 AEHFTIELTEENFRRLQAEHDR-QAKELFLLRKTLEEME-LRI---ETQKQTLNARDESI 318
Query: 353 YKTLDLAHDYQDKCKQLQ--NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
K L++ K L+ NE+ + +++ ++ V+L K+KE L+E +
Sbjct: 319 KKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQ 378
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-------L 463
L + K L+ +E + S + NI +L IQ + +L T++R+ +
Sbjct: 379 LQPEPAK-TKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEV 437
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KS +++ ++Q+L +K+++ + K + L N+ +QH+E+ K L Q+
Sbjct: 438 YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQR 497
Query: 524 ----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLE 576
Q E DA+ +L+E + L++ ++++ D ++ + K +L ++E+ +
Sbjct: 498 AAILQTEVDALRLRLEEKESFLNKKTKQLQ-DLTEEKGTLAGEIRDMKDMLEVKER---K 553
Query: 577 INVLEEK 583
INVL++K
Sbjct: 554 INVLQKK 560
Score = 56.4 bits (130), Expect = 3e-07
Identities = 65/337 (19%), Positives = 150/337 (44%), Gaps = 22/337 (6%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D A++ L EA ++R +++ + + + E+E+FR D ++K + ++EL +
Sbjct: 593 DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEK 652
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK------ENYDTVM 409
D ++ L S + +++L ++ + + K +E L+ N +
Sbjct: 653 ESSLIDLKEHASSL----ASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDS 708
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV----NDETLLLTQERDLLK 465
R+N + D +K L++ + ++ + L + ++ V ND+ + + L
Sbjct: 709 RMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTL 768
Query: 466 SKVNEERSRCAVIE--QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
+ ++ + A ++ QQL +K+N +++L++ ++ + QHL++++ +
Sbjct: 769 RHMKDQNKKVANLKHNQQLEKKKN--AQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 826
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVL 580
Q DA A+L Q+ L E + N + R + I++ + +L + I +L
Sbjct: 827 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALL 886
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLL-ESKVECQRRRR 616
E ++ K +A EK L+ + K + Q R +
Sbjct: 887 ELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMK 923
Score = 49.2 bits (112), Expect = 5e-05
Identities = 68/271 (25%), Positives = 128/271 (47%), Gaps = 22/271 (8%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ KQ ++K+S L T+L+ ++ S+ + I+VLKE+ + L V L
Sbjct: 450 DQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR 509
Query: 424 EAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
L EKE F + T K++Q + +E L E +K + + + V+++++
Sbjct: 510 LRLEEKESFLNKKT--------KQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKI 561
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
Q Q + K+ L + VK+L+ L LE+A L++ + E+L +
Sbjct: 562 ENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL-----ATLEEA-LSEKERIIERL-K 614
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ-HKLEINVLE-EKQREEIKLYRLQLAQAAE 600
+RE ++ RL+E ++SF K+ ++E+ + L+ + E E ++K + LA A
Sbjct: 615 EQRERDDRERLEE---IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL 671
Query: 601 KLGLLESKVECQRRRRGETAARLHAAL-QAH 630
K +E ++ E ++L A L +AH
Sbjct: 672 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAH 702
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/299 (24%), Positives = 131/299 (43%), Gaps = 39/299 (13%)
Query: 354 KTLDLAHDYQDKCKQLQNEK---KSLE---EQLNTELDNVNVMLSNKDKEIDVLKEN--- 404
K +L +DK KQL N K KSL+ +T L + LS K++ I+ LKE
Sbjct: 560 KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 619
Query: 405 --------YDTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
++ + NK L + V L+ E EKE S++ +L + S+ L
Sbjct: 620 DDRERLEEIESFRKENKDLKEKVNALQAELTEKE--------SSLIDLKEHASSLASAGL 671
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
+ L+ + +++ C+ +E QL + N + +F D ++K L + ++
Sbjct: 672 KRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFAD-QIKQLDKEASYYRD 730
Query: 516 ELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
E C + D +L L+E + + + ++++ L ++ D NK++ ++ +L
Sbjct: 731 E--CGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQ-NKKVANLKHNQQL 787
Query: 576 E----INVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
E +LEE ++RE+ Q Q E + LE R+ T ARL + Q+
Sbjct: 788 EKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEK----TRQELDATKARLASTQQS 842
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa
protein.
Length = 976
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.5 bits (93), Expect = 0.009
Identities = 58/281 (20%), Positives = 125/281 (44%), Gaps = 23/281 (8%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQ 370
+ L+ +E R K+ E E + + + ES+L + + + ++LQ
Sbjct: 94 SDLENSEGLSR-VFSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQ 152
Query: 371 --NEKKSL--EE--QLNTEL---DNVNVMLSNKDKEIDVLK----ENYDTVMRLNKQL-T 416
NEK SL EE Q N +L +N L N KE + Y+ +Q+
Sbjct: 153 FGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 212
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
D N+E+ + +++ E++ +++ ++ L QE K ++N++ + +
Sbjct: 213 DLNNNIEKMITAHGELRVQAENSRLEMHFKLKEDYEKIQHLEQE---YKKEINDKEKQVS 269
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++ Q+ EK+N+ ++ + ++V L + +LQ LK +KQ + +L++
Sbjct: 270 LLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQ--HHLTKELEDI 327
Query: 537 QEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+ L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 328 KVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 35.1 bits (77), Expect = 0.80
Identities = 38/174 (21%), Positives = 80/174 (45%), Gaps = 11/174 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A K
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK----L 695
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD-T 407
+ E+ K H + ++ K ++ + E D+ + +K++E L+ + +
Sbjct: 696 QKEIDKRCQ--HKIAEMVALMEKHKHQYDKIIE-ERDSELGLYKSKEQEQSSLRASLEIE 752
Query: 408 VMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ L +L K LE E EKEK ++ K N L ++ LL T E
Sbjct: 753 LSNLKAELLSVKKQLEIEREEKEKLKREA-KENTATLKEKKDKKTQTFLLETPE 805
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.1 bits (92), Expect = 0.012
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVKN 421
Q+ K ++ ++K+++E L + V++ L +E D++KEN T N C ++
Sbjct: 135 QENRKIIEAQRKAIQE-LQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDLL--------------- 464
E+ +K ++ + T+ +LN I+ + E L + E L
Sbjct: 194 AEKT-KKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQH 252
Query: 465 -----KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
K ++N++ + +++ Q+ EK+N+ ++ + ++V L + +LQ LK
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQ 312
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+KQ + +L++ + L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 313 SIEKQ--HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 35.1 bits (77), Expect = 0.80
Identities = 38/174 (21%), Positives = 80/174 (45%), Gaps = 11/174 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A K
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK----L 695
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD-T 407
+ E+ K H + ++ K ++ + E D+ + +K++E L+ + +
Sbjct: 696 QKEIDKRCQ--HKIAEMVALMEKHKHQYDKIIE-ERDSELGLYKSKEQEQSSLRASLEIE 752
Query: 408 VMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ L +L K LE E EKEK ++ K N L ++ LL T E
Sbjct: 753 LSNLKAELLSVKKQLEIEREEKEKLKREA-KENTATLKEKKDKKTQTFLLETPE 805
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.1 bits (92), Expect = 0.012
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVKN 421
Q+ K ++ ++K+++E L + V++ L +E D++KEN T N C ++
Sbjct: 135 QENRKIIEAQRKAIQE-LQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDLL--------------- 464
E+ +K ++ + T+ +LN I+ + E L + E L
Sbjct: 194 AEKT-KKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQH 252
Query: 465 -----KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
K ++N++ + +++ Q+ EK+N+ ++ + ++V L + +LQ LK
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQ 312
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+KQ + +L++ + L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 313 SIEKQ--HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 35.1 bits (77), Expect = 0.80
Identities = 38/174 (21%), Positives = 80/174 (45%), Gaps = 11/174 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A K
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK----L 695
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD-T 407
+ E+ K H + ++ K ++ + E D+ + +K++E L+ + +
Sbjct: 696 QKEIDKRCQ--HKIAEMVALMEKHKHQYDKIIE-ERDSELGLYKSKEQEQSSLRASLEIE 752
Query: 408 VMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ L +L K LE E EKEK ++ K N L ++ LL T E
Sbjct: 753 LSNLKAELLSVKKQLEIEREEKEKLKREA-KENTATLKEKKDKKTQTFLLETPE 805
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.1 bits (92), Expect = 0.012
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVKN 421
Q+ K ++ ++K+++E L + V++ L +E D++KEN T N C ++
Sbjct: 135 QENRKIIEAQRKAIQE-LQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDLL--------------- 464
E+ +K ++ + T+ +LN I+ + E L + E L
Sbjct: 194 AEKT-KKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQH 252
Query: 465 -----KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
K ++N++ + +++ Q+ EK+N+ ++ + ++V L + +LQ LK
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQ 312
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+KQ + +L++ + L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 313 SIEKQ--HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 34.3 bits (75), Expect = 1.4
Identities = 31/150 (20%), Positives = 69/150 (46%), Gaps = 19/150 (12%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDA------- 341
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEI 699
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC-----------KQLQNEKKSLEEQLNTELDNVNVM 390
K+ H +E+ ++ DK K + E+ SL L EL N+
Sbjct: 700 DKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAE 759
Query: 391 LSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
L + K++++ +E + + R K+ T +K
Sbjct: 760 LLSVKKQLEIEREEKEKLKREAKENTATLK 789
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.1 bits (92), Expect = 0.012
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVKN 421
Q+ K ++ ++K+++E L + V++ L +E D++KEN T N C ++
Sbjct: 135 QENRKIIEAQRKAIQE-LQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDLL--------------- 464
E+ +K ++ + T+ +LN I+ + E L + E L
Sbjct: 194 AEKT-KKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQH 252
Query: 465 -----KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
K ++N++ + +++ Q+ EK+N+ ++ + ++V L + +LQ LK
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQ 312
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+KQ + +L++ + L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 313 SIEKQ--HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 35.1 bits (77), Expect = 0.80
Identities = 38/174 (21%), Positives = 80/174 (45%), Gaps = 11/174 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A K
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVK----L 695
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD-T 407
+ E+ K H + ++ K ++ + E D+ + +K++E L+ + +
Sbjct: 696 QKEIDKRCQ--HKIAEMVALMEKHKHQYDKIIE-ERDSELGLYKSKEQEQSSLRASLEIE 752
Query: 408 VMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ L +L K LE E EKEK ++ K N L ++ LL T E
Sbjct: 753 LSNLKAELLSVKKQLEIEREEKEKLKREA-KENTATLKEKKDKKTQTFLLETPE 805
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 61.7 bits (143), Expect = 8e-09
Identities = 79/350 (22%), Positives = 159/350 (45%), Gaps = 32/350 (9%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+++ L+ + E++ ++ K T++ E EL + + + + + + +K E
Sbjct: 399 EKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAE 458
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E TE + + +L ++KE+ L+ + + + VK+L+ LE EK +
Sbjct: 459 ELKGTEQELIG-LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLKNTELT 517
Query: 438 SNITEL---NKRI-QSVNDETL-LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S+ +L NK + Q +D TL L Q+ D+ +K EER + Q E Q
Sbjct: 518 SHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ------ 571
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ-----EFQEQLDRAEREM 547
L NE++ +R+ L+ +++E+KC K E+ + Q ++ E+L + + +
Sbjct: 572 ------LRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
Query: 548 --ENDARLKENNIVD-SFNKQILRIE--EQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+ A K+ N+ + NK L +E +Q EI +K+ E+ K+ L + EK
Sbjct: 626 KKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKA 685
Query: 603 GLL-ESKVECQR---RRRGETAARLHAALQAHWRHALRILAAPHHDLGTH 648
++ + V+ Q+ +R A + A ++ H +I+ +LG +
Sbjct: 686 KVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLY 735
Score = 54.0 bits (124), Expect = 2e-06
Identities = 69/297 (23%), Positives = 132/297 (44%), Gaps = 26/297 (8%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQN 371
+ E ++K + +V + + + K L ++ D + ++K K Q +N
Sbjct: 250 IQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSEN 309
Query: 372 EKKSLEEQ--LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+S+E+Q L EL+++ V L L+E+ + QLT+ + E K
Sbjct: 310 LKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKA 369
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ AH +TE + S+ E LL T+++ L K NE++ + ++ +L +K ++
Sbjct: 370 RAAHSFV---VTEFETTVCSL--EELLRTEQQRLEK---NEDQLK--ILTMELQKKSSEL 419
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
E+ K + + E++ L++ L + E + KQ E + E+L E+E+
Sbjct: 420 EEMTKLTNNKEVELEELKK--VLGEKETLLYENKQFE--------KIAEELKGTEQELIG 469
Query: 550 --DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
AR KE + ++ I E+ + E+ L+ + E KL +L KL L
Sbjct: 470 LLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENE-KLKNTELTSHCNKLSL 525
Score = 41.1 bits (92), Expect = 0.012
Identities = 48/238 (20%), Positives = 109/238 (45%), Gaps = 30/238 (12%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVKN 421
Q+ K ++ ++K+++E L + V++ L +E D++KEN T N C ++
Sbjct: 135 QENRKIIEAQRKAIQE-LQFGNEKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARS 193
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDLL--------------- 464
E+ +K ++ + T+ +LN I+ + E L + E L
Sbjct: 194 AEKT-KKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQH 252
Query: 465 -----KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKC 519
K ++N++ + +++ Q+ EK+N+ ++ + ++V L + +LQ LK
Sbjct: 253 LEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQ 312
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRA---EREMENDARLKENNIVDSFNKQILRIEEQHK 574
+KQ + +L++ + L R+ ++ +E D ++ I ++ ++EE +K
Sbjct: 313 SIEKQ--HHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNK 368
Score = 34.3 bits (75), Expect = 1.4
Identities = 31/150 (20%), Positives = 69/150 (46%), Gaps = 19/150 (12%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDA------- 341
+KV++ + + ++ + +T++ + + + + E ++ EVE +V+AD+A
Sbjct: 641 IKVNKL-ELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIADEAVKLQKEI 699
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC-----------KQLQNEKKSLEEQLNTELDNVNVM 390
K+ H +E+ ++ DK K + E+ SL L EL N+
Sbjct: 700 DKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAE 759
Query: 391 LSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
L + K++++ +E + + R K+ T +K
Sbjct: 760 LLSVKKQLEIEREEKEKLKREAKENTATLK 789
>AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens
cDNA FLJ34363 fis, clone FEBRA2015042. ).
Length = 936
Score = 61.3 bits (142), Expect = 1e-08
Identities = 84/384 (21%), Positives = 173/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 340 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 399
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 400 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 459
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 460 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 519
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 520 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 579
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ ER + LKE +++
Sbjct: 580 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEERHQQRHKSLKEAHVLAFQTM 638
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 639 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 697
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 698 LASLRSELNHQHAAAIDLLRHNHH 721
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 179 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 237
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 238 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 292
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 293 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 349
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 405
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 406 ----DKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 457
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 60.9 bits (141), Expect = 1e-08
Identities = 84/361 (23%), Positives = 165/361 (45%), Gaps = 39/361 (10%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + ++LR+ + + + E +R +K C +E ++ +K+ + +S L
Sbjct: 572 RTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN-CLLETAKL---KLEKEFINLQSAL 627
Query: 353 Y-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR- 410
+ D H + LQ LEE +L N ++L+ + E L+E + + +
Sbjct: 628 ESERRDRTHG-SEIINDLQGRICGLEE----DLKNGKILLAKVELEKRQLQERFTDLEKE 682
Query: 411 ---LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDL-- 463
+ +T +K ++++LE+E+ H +TK+ + + NK +S+ + + E+ L
Sbjct: 683 KSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLE 742
Query: 464 ---LKSKVN----EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
LK KV E RC++++ L + Q + +E+LK+ D L+ +V+ L +E Q+ +
Sbjct: 743 ERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIE-QETQ 801
Query: 517 LKCHYQKQL--EDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNKQILRIEEQH 573
+C Q L + + L+ ++QL + ME L++ N K+ + Q
Sbjct: 802 KRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA--ELRKERQDADGQM 859
Query: 574 KLEINVLEEKQREEIKLYRLQLAQAAE------KLGL-LESKVECQRRRRGETAARLHAA 626
K E+ E ++ LY+ Q+ + E KLG L+ K + + R AA+L
Sbjct: 860 K-ELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEIT 918
Query: 627 L 627
L
Sbjct: 919 L 919
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/335 (20%), Positives = 151/335 (45%), Gaps = 20/335 (5%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAED---RHRKALEKMICEVENFRVVADDAQKKTSH 347
++ AK A+ ++ + L + E+ K + C+++ + ++ K+
Sbjct: 725 IEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDV 784
Query: 348 FESELYK-TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
++ TL + + Q +C QN+ K +Q+NT L L ++ + +K N +
Sbjct: 785 LNEDVRNLTLKIEQETQKRCLT-QNDLKMQTQQVNT-LKMSEKQLKQENNHLMEMKMNLE 842
Query: 407 TV-MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD 462
L K+ D +K L++ LE E++ K+ + EL + + E L +E
Sbjct: 843 KQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE----EKTKLGKELQ 898
Query: 463 LLKSKVNEER-SRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
K ++ +ER S A +E L + + Q + + + + D E + + + LE+ K + H
Sbjct: 899 QKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEI-KEMMARH 957
Query: 521 YQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+ E DA +A L+E L + N+ + + NN + +Q+ R++++ ++
Sbjct: 958 KQELTEKDATIASLEETNRTLTSDVANLANE-KEELNNKLKDVQEQLSRLKDE-EISAAA 1015
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++ + +++ R QA KL + ++ E +R
Sbjct: 1016 IKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKR 1050
Score = 41.5 bits (93), Expect = 0.009
Identities = 60/306 (19%), Positives = 132/306 (43%), Gaps = 27/306 (8%)
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCK----QLQNEKKSLEEQLN---------TEL 384
+ + QKK E L + + + KCK +L+ K LEE++ +L
Sbjct: 442 SQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQL 501
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
+ +L +K+ E K +++ + N L + V +L++ LE K + +++ + ++N
Sbjct: 502 EREKALLQHKNAEYQ-RKADHEADKKRN--LENDVNSLKDQLEDLKKRNQNSQISTEKVN 558
Query: 445 KRIQSVNDETLLLTQERDL---LKSKVNEERSRCAVIEQQLCEKQNQ-CSEVLKKCDFLD 500
+ + +++ LL E D L+ E + +E + Q++ C K L+
Sbjct: 559 QLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLK-LE 617
Query: 501 NEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE---REMENDARLKENN 557
E L+ LE ++ + + H + + D + ++ +E L + ++E + R +
Sbjct: 618 KEFINLQSALESERRD-RTHGSEIIND-LQGRICGLEEDLKNGKILLAKVELEKRQLQER 675
Query: 558 IVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
D K+ +E ++ V+++ +E ++ A+ A+K + ES E +
Sbjct: 676 FTD-LEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMK 734
Query: 618 ETAARL 623
E +L
Sbjct: 735 EMEKKL 740
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 60.9 bits (141), Expect = 1e-08
Identities = 84/361 (23%), Positives = 165/361 (45%), Gaps = 39/361 (10%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + ++LR+ + + + E +R +K C +E ++ +K+ + +S L
Sbjct: 521 RTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN-CLLETAKL---KLEKEFINLQSAL 576
Query: 353 Y-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR- 410
+ D H + LQ LEE +L N ++L+ + E L+E + + +
Sbjct: 577 ESERRDRTHG-SEIINDLQGRICGLEE----DLKNGKILLAKVELEKRQLQERFTDLEKE 631
Query: 411 ---LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDL-- 463
+ +T +K ++++LE+E+ H +TK+ + + NK +S+ + + E+ L
Sbjct: 632 KSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLE 691
Query: 464 ---LKSKVN----EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
LK KV E RC++++ L + Q + +E+LK+ D L+ +V+ L +E Q+ +
Sbjct: 692 ERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIE-QETQ 750
Query: 517 LKCHYQKQL--EDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNKQILRIEEQH 573
+C Q L + + L+ ++QL + ME L++ N K+ + Q
Sbjct: 751 KRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA--ELRKERQDADGQM 808
Query: 574 KLEINVLEEKQREEIKLYRLQLAQAAE------KLGL-LESKVECQRRRRGETAARLHAA 626
K E+ E ++ LY+ Q+ + E KLG L+ K + + R AA+L
Sbjct: 809 K-ELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEIT 867
Query: 627 L 627
L
Sbjct: 868 L 868
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/335 (20%), Positives = 151/335 (45%), Gaps = 20/335 (5%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAED---RHRKALEKMICEVENFRVVADDAQKKTSH 347
++ AK A+ ++ + L + E+ K + C+++ + ++ K+
Sbjct: 674 IEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDV 733
Query: 348 FESELYK-TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
++ TL + + Q +C QN+ K +Q+NT L L ++ + +K N +
Sbjct: 734 LNEDVRNLTLKIEQETQKRCLT-QNDLKMQTQQVNT-LKMSEKQLKQENNHLMEMKMNLE 791
Query: 407 TV-MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD 462
L K+ D +K L++ LE E++ K+ + EL + + E L +E
Sbjct: 792 KQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE----EKTKLGKELQ 847
Query: 463 LLKSKVNEER-SRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
K ++ +ER S A +E L + + Q + + + + D E + + + LE+ K + H
Sbjct: 848 QKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEI-KEMMARH 906
Query: 521 YQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+ E DA +A L+E L + N+ + + NN + +Q+ R++++ ++
Sbjct: 907 KQELTEKDATIASLEETNRTLTSDVANLANE-KEELNNKLKDVQEQLSRLKDE-EISAAA 964
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++ + +++ R QA KL + ++ E +R
Sbjct: 965 IKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKR 999
Score = 42.7 bits (96), Expect = 0.004
Identities = 61/314 (19%), Positives = 136/314 (43%), Gaps = 27/314 (8%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK----QLQNEKKSLEEQLN---- 381
E ++ + ++ QKK E L + + + KCK +L+ K LEE++
Sbjct: 383 ETDSIQSRKNEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKS 442
Query: 382 -----TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+L+ +L +K+ E K +++ + N L + V +L++ LE K + ++
Sbjct: 443 VESALRQLEREKALLQHKNAEYQ-RKADHEADKKRN--LENDVNSLKDQLEDLKKRNQNS 499
Query: 437 KSNITELNKRIQSVNDETLLLTQERDL---LKSKVNEERSRCAVIEQQLCEKQNQ-CSEV 492
+ + ++N+ + +++ LL E D L+ E + +E + Q++ C
Sbjct: 500 QISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLE 559
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE---REMEN 549
K L+ E L+ LE ++ + + H + + D + ++ +E L + ++E
Sbjct: 560 TAKLK-LEKEFINLQSALESERRD-RTHGSEIIND-LQGRICGLEEDLKNGKILLAKVEL 616
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
+ R + D K+ +E ++ V+++ +E ++ A+ A+K + ES
Sbjct: 617 EKRQLQERFTD-LEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIE 675
Query: 610 ECQRRRRGETAARL 623
E + E +L
Sbjct: 676 EAKSEAMKEMEKKL 689
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 60.9 bits (141), Expect = 1e-08
Identities = 84/361 (23%), Positives = 165/361 (45%), Gaps = 39/361 (10%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + ++LR+ + + + E +R +K C +E ++ +K+ + +S L
Sbjct: 612 RTESDTAARLRKTQAESSKQIQQLESNNRDLQDKN-CLLETAKL---KLEKEFINLQSAL 667
Query: 353 Y-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR- 410
+ D H + LQ LEE +L N ++L+ + E L+E + + +
Sbjct: 668 ESERRDRTHG-SEIINDLQGRICGLEE----DLKNGKILLAKVELEKRQLQERFTDLEKE 722
Query: 411 ---LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDL-- 463
+ +T +K ++++LE+E+ H +TK+ + + NK +S+ + + E+ L
Sbjct: 723 KSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLE 782
Query: 464 ---LKSKVN----EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
LK KV E RC++++ L + Q + +E+LK+ D L+ +V+ L +E Q+ +
Sbjct: 783 ERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIE-QETQ 841
Query: 517 LKCHYQKQL--EDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNKQILRIEEQH 573
+C Q L + + L+ ++QL + ME L++ N K+ + Q
Sbjct: 842 KRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA--ELRKERQDADGQM 899
Query: 574 KLEINVLEEKQREEIKLYRLQLAQAAE------KLGL-LESKVECQRRRRGETAARLHAA 626
K E+ E ++ LY+ Q+ + E KLG L+ K + + R AA+L
Sbjct: 900 K-ELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEIT 958
Query: 627 L 627
L
Sbjct: 959 L 959
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/335 (20%), Positives = 151/335 (45%), Gaps = 20/335 (5%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAED---RHRKALEKMICEVENFRVVADDAQKKTSH 347
++ AK A+ ++ + L + E+ K + C+++ + ++ K+
Sbjct: 765 IEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDV 824
Query: 348 FESELYK-TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
++ TL + + Q +C QN+ K +Q+NT L L ++ + +K N +
Sbjct: 825 LNEDVRNLTLKIEQETQKRCLT-QNDLKMQTQQVNT-LKMSEKQLKQENNHLMEMKMNLE 882
Query: 407 TV-MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD 462
L K+ D +K L++ LE E++ K+ + EL + + E L +E
Sbjct: 883 KQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE----EKTKLGKELQ 938
Query: 463 LLKSKVNEER-SRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
K ++ +ER S A +E L + + Q + + + + D E + + + LE+ K + H
Sbjct: 939 QKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEI-KEMMARH 997
Query: 521 YQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+ E DA +A L+E L + N+ + + NN + +Q+ R++++ ++
Sbjct: 998 KQELTEKDATIASLEETNRTLTSDVANLANE-KEELNNKLKDVQEQLSRLKDE-EISAAA 1055
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++ + +++ R QA KL + ++ E +R
Sbjct: 1056 IKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKR 1090
Score = 41.5 bits (93), Expect = 0.009
Identities = 60/306 (19%), Positives = 132/306 (43%), Gaps = 27/306 (8%)
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCK----QLQNEKKSLEEQLN---------TEL 384
+ + QKK E L + + + KCK +L+ K LEE++ +L
Sbjct: 482 SQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQL 541
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
+ +L +K+ E K +++ + N L + V +L++ LE K + +++ + ++N
Sbjct: 542 EREKALLQHKNAEYQ-RKADHEADKKRN--LENDVNSLKDQLEDLKKRNQNSQISTEKVN 598
Query: 445 KRIQSVNDETLLLTQERDL---LKSKVNEERSRCAVIEQQLCEKQNQ-CSEVLKKCDFLD 500
+ + +++ LL E D L+ E + +E + Q++ C K L+
Sbjct: 599 QLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLK-LE 657
Query: 501 NEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE---REMENDARLKENN 557
E L+ LE ++ + + H + + D + ++ +E L + ++E + R +
Sbjct: 658 KEFINLQSALESERRD-RTHGSEIIND-LQGRICGLEEDLKNGKILLAKVELEKRQLQER 715
Query: 558 IVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
D K+ +E ++ V+++ +E ++ A+ A+K + ES E +
Sbjct: 716 FTD-LEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMK 774
Query: 618 ETAARL 623
E +L
Sbjct: 775 EMEKKL 780
>BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20
protein.
Length = 975
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 346 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 405
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 406 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 465
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 466 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 525
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 526 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 585
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 586 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 644
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 645 LLLDMYRSAPKEQRDKVQLMAAE 667
Score = 44.0 bits (99), Expect = 0.002
Identities = 59/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 587 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 646
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + EKKS EL+++ L + +DKE K+ D +
Sbjct: 647 LDMYRSAPKEQRDKVQLMAAEKKS-----KAELEDLRQRLKDLEDKEKKENKKMADEDAL 701
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 702 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 756
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 757 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 811
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 812 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 871
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 872 KEKDMFNFKRAQ--EDISRLRRKLETTKK 898
Score = 39.9 bits (89), Expect = 0.028
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 496 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 555
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 556 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 615
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 616 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 669
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 670 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 723
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 724 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 763
Score = 33.5 bits (73), Expect = 2.4
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 165 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 222
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 223 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 279
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 280 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 339
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 340 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 387
>BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20
protein.
Length = 975
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 346 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 405
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 406 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 465
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 466 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 525
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 526 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 585
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 586 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 644
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 645 LLLDMYRSAPKEQRDKVQLMAAE 667
Score = 44.0 bits (99), Expect = 0.002
Identities = 59/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 587 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 646
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + EKKS EL+++ L + +DKE K+ D +
Sbjct: 647 LDMYRSAPKEQRDKVQLMAAEKKS-----KAELEDLRQRLKDLEDKEKKENKKMADEDAL 701
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 702 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 756
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 757 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 811
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 812 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 871
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 872 KEKDMFNFKRAQ--EDISRLRRKLETTKK 898
Score = 39.9 bits (89), Expect = 0.028
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 496 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 555
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 556 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 615
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 616 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 669
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 670 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 723
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 724 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 763
Score = 33.5 bits (73), Expect = 2.4
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 165 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 222
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 223 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 279
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 280 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 339
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 340 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 387
>BC063115-1|AAH63115.1| 695|Homo sapiens RNF20 protein protein.
Length = 695
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 346 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 405
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 406 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 465
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 466 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 525
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 526 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 585
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 586 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 644
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 645 LLLDMYRSAPKEQRDKVQLMAAE 667
Score = 33.5 bits (73), Expect = 2.4
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 165 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 222
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 223 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 279
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 280 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 339
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 340 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 387
>AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20
protein.
Length = 977
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 348 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 407
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 408 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 467
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 468 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 527
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 528 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 587
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 588 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 646
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 647 LLLDMYRSAPKEQRDKVQLMAAE 669
Score = 44.0 bits (99), Expect = 0.002
Identities = 59/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 589 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 648
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + EKKS EL+++ L + +DKE K+ D +
Sbjct: 649 LDMYRSAPKEQRDKVQLMAAEKKS-----KAELEDLRQRLKDLEDKEKKENKKMADEDAL 703
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 704 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 758
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 759 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 813
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 814 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 873
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 874 KEKDMFNFKRAQ--EDISRLRRKLETTKK 900
Score = 39.9 bits (89), Expect = 0.028
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 498 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 557
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 558 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 617
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 618 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 671
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 672 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 725
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 726 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 765
Score = 33.5 bits (73), Expect = 2.4
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 167 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 224
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 225 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 281
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 282 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 341
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 342 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 389
>AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20
protein.
Length = 977
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 348 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 407
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 408 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 467
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 468 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 527
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 528 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 587
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 588 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 646
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 647 LLLDMYRSAPKEQRDKVQLMAAE 669
Score = 44.0 bits (99), Expect = 0.002
Identities = 59/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 589 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 648
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + EKKS EL+++ L + +DKE K+ D +
Sbjct: 649 LDMYRSAPKEQRDKVQLMAAEKKS-----KAELEDLRQRLKDLEDKEKKENKKMADEDAL 703
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 704 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 758
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 759 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 813
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 814 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 873
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 874 KEKDMFNFKRAQ--EDISRLRRKLETTKK 900
Score = 39.9 bits (89), Expect = 0.028
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 498 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 557
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 558 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 617
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 618 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 671
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 672 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 725
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 726 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 765
Score = 33.5 bits (73), Expect = 2.4
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 167 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 224
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 225 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 281
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 282 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 341
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 342 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 389
>AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens
cDNA FLJ12470 fis, clone NT2RM1000885, weakly similar to
HYPOTHETICAL 97.1 KD PROTEIN R05D3.4 IN CHROMOSOME III.
).
Length = 975
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 346 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 405
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 406 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 465
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 466 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 525
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 526 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 585
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 586 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 644
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 645 LLLDMYRSAPKEQRDKVQLMAAE 667
Score = 42.3 bits (95), Expect = 0.005
Identities = 58/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 587 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 646
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + E+KS EL+++ L + +DKE K+ D +
Sbjct: 647 LDMYRSAPKEQRDKVQLMAAEEKS-----KAELEDLRQRLKDLEDKEKKENKKMADEEAL 701
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 702 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 756
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 757 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 811
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 812 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 871
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 872 KEKDMFNFKRAQ--EDISRLRRKLETTKK 898
Score = 40.3 bits (90), Expect = 0.021
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 496 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 555
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 556 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 615
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 616 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEEK 669
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 670 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEEALRKIRAVEEQIEYLQKKLAM-AKQ 723
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 724 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 763
Score = 34.3 bits (75), Expect = 1.4
Identities = 42/228 (18%), Positives = 95/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 165 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 222
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 223 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 279
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + +++F+E E E
Sbjct: 280 KIRKREQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINVRKFEEMNAELEENKELA 339
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 340 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 387
>AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens
cDNA FLJ12238 fis, clone MAMMA1001260, weakly similar to
HYPOTHETICAL 97.1 KD PROTEIN R05D3.4 IN CHROMOSOME III.
).
Length = 746
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 117 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 176
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 177 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 236
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 237 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 296
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 297 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 357 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 415
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 416 LLLDMYRSAPKEQRDKVQLMAAE 438
Score = 44.0 bits (99), Expect = 0.002
Identities = 59/329 (17%), Positives = 151/329 (45%), Gaps = 23/329 (6%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 358 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 417
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKENYD-TVM 409
L + +DK + + EKKS EL+++ L + +DKE K+ D +
Sbjct: 418 LDMYRSAPKEQRDKVQLMAAEKKS-----KAELEDLRQRLKDLEDKEKKENKKMADEDAL 472
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
R + + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K
Sbjct: 473 RKIRAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK-- 527
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+ + ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E
Sbjct: 528 -DDANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHL 582
Query: 529 VLAKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQR 585
+ + + +++L + +E + R ++ + D Q+ L ++ H + ++E
Sbjct: 583 LQSNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVT 642
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+E ++ + AQ E + L K+E ++
Sbjct: 643 KEKDMFNFKRAQ--EDISRLRRKLETTKK 669
Score = 39.9 bits (89), Expect = 0.028
Identities = 54/280 (19%), Positives = 126/280 (45%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 267 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 326
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 327 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 386
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 387 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 440
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K +K ++ L K++ +EQ++ ++++ A+
Sbjct: 441 SKA-----ELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 494
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 495 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 534
>AK000697-1|BAA91326.1| 670|Homo sapiens protein ( Homo sapiens
cDNA FLJ20690 fis, clone KAIA2769. ).
Length = 670
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 330 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 389
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 390 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 449
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 450 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 509
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 510 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 569
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 570 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 628
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 629 LLLDMYRSAPKEQRDKVQLMAAE 651
Score = 33.9 bits (74), Expect = 1.8
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 149 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 206
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 207 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 263
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 264 KIRKRQQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 323
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 324 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 371
>AK000389-1|BAA91134.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ20382 fis, clone KAIA2779. ).
Length = 682
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 330 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 389
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 390 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 449
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 450 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 509
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 510 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 569
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 570 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 628
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 629 LLLDMYRSAPKEQRDKVQLMAAE 651
Score = 33.9 bits (74), Expect = 1.8
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 149 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 206
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 207 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 263
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ L+ + + + + + ++ + ++F+E E E
Sbjct: 264 KIRKRQQRLNRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 323
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 324 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 371
>AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20
protein.
Length = 975
Score = 60.5 bits (140), Expect = 2e-08
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 14/323 (4%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT 355
+ KLR+ + +T ++ + R A+E+++ E +R + ++ ++ L +
Sbjct: 346 LEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEA 405
Query: 356 LDLAHD----YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L H +Q + + ++ ++ SL ++L TE+ + L+ KE ++L+ ++ +
Sbjct: 406 RTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLAQVRKEYEMLRIEFEQTLAA 465
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVN 469
N+Q + + + + + K + ++++ + L LL+S+ +
Sbjct: 466 NEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLRSGSALLQSQSS 525
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQKNELKCHYQKQLEDA 528
E + E + + K D NE+K+ R E ++ + +++ E
Sbjct: 526 TEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERERERE 585
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE- 587
+ + +++L +E+E ++ A+ KE D K+ I +Q K+E+ +E Q+E
Sbjct: 586 KEKEREREKQKLKESEKERDS-AKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMK 644
Query: 588 --IKLYRLQLAQAAEKLGLLESK 608
+ +YR + +K+ L+ ++
Sbjct: 645 LLLDMYRSAPKEQRDKVQLMAAE 667
Score = 43.2 bits (97), Expect = 0.003
Identities = 56/327 (17%), Positives = 150/327 (45%), Gaps = 19/327 (5%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE 351
++ ++ KL+E+ ++ D+ + +H +K ++ ++ AQ+ +
Sbjct: 587 EKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLL 646
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
L + +DK + + EKKS E +L L +K+K+ + + D + ++
Sbjct: 647 LDMYRSAPKEQRDKVQLMAAEKKSKAEL--EDLRQRLKDLEDKEKKENTKMADEDALRKI 704
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ + + ++ L++ L K ++ S + + + + ++ + L Q+ L+ K +
Sbjct: 705 -RAVEEQIEYLQKKLAMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQ---LREK---D 757
Query: 472 RSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+ ++ +++ K NQ ++LK + + L ++V TL+ ++ Q ++ +K E +
Sbjct: 758 DANFKLMSERI--KSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEK--EHLLQ 813
Query: 531 AKLQEFQEQLDRAEREMENDAR--LKENNIVDSFNKQI-LRIEEQHKLEINVLEEKQREE 587
+ + +++L + +E + R ++ + D Q+ L ++ H + ++E +E
Sbjct: 814 SNIGTGEKELGLRTQALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKE 873
Query: 588 IKLYRLQLAQAAEKLGLLESKVECQRR 614
++ + AQ E + L K+E ++
Sbjct: 874 KDMFNFKRAQ--EDISRLRRKLETTKK 898
Score = 39.1 bits (87), Expect = 0.049
Identities = 54/280 (19%), Positives = 125/280 (44%), Gaps = 17/280 (6%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKT-SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
R+++ L + ++ R+ + A ++ S E + +L D +D Q K S E
Sbjct: 496 RYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQE 555
Query: 378 E--QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ--LTDCVKNLEEALEKEKFAH 433
+ ++ ++ D ++KE + +E R ++ L + K + A +KEK H
Sbjct: 556 DANEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKH 615
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
D + E+ K+++ + +E LL + R A EQ+ + Q +E
Sbjct: 616 DDGRKKEAEIIKQLKIELKKAQESQKEMKLLL-----DMYRSAPKEQR-DKVQLMAAEKK 669
Query: 494 KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
K E++ LRQ L+ +++ K K ++ L K++ +EQ++ ++++ A+
Sbjct: 670 SKA-----ELEDLRQRLKDLEDKEKKENTKMADEDALRKIRAVEEQIEYLQKKLAM-AKQ 723
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+E ++ + E+ + I ++++ + ++ ++L
Sbjct: 724 EEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKL 763
Score = 35.5 bits (78), Expect = 0.60
Identities = 43/228 (18%), Positives = 94/228 (41%), Gaps = 6/228 (2%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
+ + +E QL +++ +S D L+E + + R + + +EEA+++
Sbjct: 165 SSSEEMESQLQERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLI--VEEAVQELN 222
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ EL +Q ++ ++QE L+SKV SR +V+E + + Q
Sbjct: 223 SFLAQENMRLQELTDLLQ---EKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDID 279
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME-N 549
++ K+ LD + + + + + ++ + ++F+E E E
Sbjct: 280 KIRKREQRLDRHLAEVLERVNSKGYKVYGAGSSLYGGTITINARKFEEMNAELEENKELA 339
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
RL E + +++ E+ K+E+ E+ +E YR +Q
Sbjct: 340 QNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQ 387
>BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1107
Score = 60.1 bits (139), Expect = 2e-08
Identities = 83/384 (21%), Positives = 173/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 427 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 486
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 487 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 546
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 547 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 606
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 607 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 666
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 667 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 725
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 726 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 784
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 785 LASLRSELNHQHAAAIDLLRHNHH 808
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 266 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 324
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 325 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 379
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 380 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 436
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 437 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 492
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 493 ----DKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 544
>AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 60.1 bits (139), Expect = 2e-08
Identities = 83/384 (21%), Positives = 173/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 460 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 519
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 520 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 579
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 580 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 639
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 640 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 699
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 700 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 758
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 759 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 817
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 818 LASLRSELNHQHAAAIDLLRHNHH 841
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 299 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 357
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 358 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 412
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 413 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 469
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 525
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 526 ----DKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 577
>AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 60.1 bits (139), Expect = 2e-08
Identities = 83/384 (21%), Positives = 173/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 460 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 519
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 520 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 579
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 580 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 639
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 640 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 699
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 700 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 758
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 759 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 817
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 818 LASLRSELNHQHAAAIDLLRHNHH 841
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 299 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 357
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 358 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 412
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 413 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 469
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 525
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 526 ----DKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 577
>AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 60.1 bits (139), Expect = 2e-08
Identities = 83/384 (21%), Positives = 173/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 460 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 519
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 520 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 579
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 580 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 639
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 640 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 699
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 700 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 758
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 759 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 817
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 818 LASLRSELNHQHAAAIDLLRHNHH 841
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 299 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 357
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 358 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 412
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 413 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 469
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 470 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 525
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 526 ----DKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 577
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 83/357 (23%), Positives = 163/357 (45%), Gaps = 43/357 (12%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD-DAQKKTSHFESELYK 354
D A+ +LR++ ++ S+ + E +R+ E+ +EN + D D + + E+E
Sbjct: 559 DTAV-RLRKSHTEMSKSISQLESLNRELQERNRI-LENSKSQTDKDYYQLQAILEAE--- 613
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
D HD + LQ SL+E++ N+ + + + D+L + L
Sbjct: 614 RRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID 672
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL-----LTQERDL---LKS 466
L +K+L++ LE+E H TK+ +T+ ++ I+ + L +ER+ ++
Sbjct: 673 LNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAEN 732
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-------LQKNELKC 519
+V + +C++++ L + Q + + + +++EVK L LE L +NELK
Sbjct: 733 RVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKT 792
Query: 520 H---------YQKQLEDAV-----LAKLQEFQ-EQLDRAEREMENDAR-LKENNIVDSFN 563
+KQ++ + +L EF+ QL + R E R L++ + +
Sbjct: 793 QAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYF 852
Query: 564 KQILRIEEQHKLEINVLEEKQREEI-KLYRLQLAQ--AAEKLGLLESKVECQRRRRG 617
+ + + + E +EEK RE + K+ LQ + A +L L E+K E ++ RG
Sbjct: 853 STLYKTQVKELKE--EIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARG 907
Score = 56.0 bits (129), Expect = 4e-07
Identities = 79/315 (25%), Positives = 143/315 (45%), Gaps = 35/315 (11%)
Query: 325 EKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQ--DKCKQLQNEKKSLEEQL 380
EKM+ + + ++ A+ +K + E+E+ D D + + QL NEK S QL
Sbjct: 487 EKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLS---QL 543
Query: 381 NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA---LEKEKFAHDSTK 437
+L+ N +L + L++++ + + QL + L+E LE K D
Sbjct: 544 QKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDY 603
Query: 438 SN---ITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
I E +R + + E + Q R L+ +V + +E + E Q+ +
Sbjct: 604 YQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSE 663
Query: 494 KKCDFLDNEV----KTLRQHLELQKNELKC------HYQKQLEDAVLAKLQEFQEQLDRA 543
K+ + L+ ++ K+L+Q LE + NE K + +E+A + E +++L +
Sbjct: 664 KEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL-KE 722
Query: 544 EREMENDARLKENNIVDSFNKQILRIE-----EQHKLE-INVLEEKQREEIKLYRLQLAQ 597
ERE AR K N V KQ ++ Q KLE + +E+ +E+K LQL Q
Sbjct: 723 ERE----AREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQ 778
Query: 598 AAEKLGLLESKVECQ 612
+ K LL+++++ Q
Sbjct: 779 ESNKRLLLQNELKTQ 793
Score = 51.6 bits (118), Expect = 9e-06
Identities = 70/324 (21%), Positives = 139/324 (42%), Gaps = 31/324 (9%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++ AK A+ ++ + + ++AE+R + +EK ++ V +Q+K H
Sbjct: 705 IEEAKSVAMCEMEKKLKEEREAREKAENRVVQ-IEKQCSMLD---VDLKQSQQKLEHLTG 760
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEIDVLKENYDT 407
+ D + + +Q N++ L+ +L T E DN+ + +EI+ L E
Sbjct: 761 NKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRL 820
Query: 408 V----MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +L KQ ++ L++ LE E++ K+ + EL + I+ N E L QE
Sbjct: 821 LEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQE 880
Query: 461 R-----------DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
DL ++K E+ ++E+Q E ++ KK + + T + H
Sbjct: 881 LQNEKETLATQLDLAETKAESEQLARGLLEEQYFE----LTQESKKAASRNRQEITDKDH 936
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+ E K +E + + +E E++ +AE E + + + +N+ +F K I
Sbjct: 937 TVSRLEEANSMLTKDIE-ILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTE 995
Query: 570 EEQHKLEINVLEE-KQREEIKLYR 592
+N L E R++ K+ R
Sbjct: 996 RTLKTQAVNKLAEIMNRKDFKIDR 1019
Score = 49.2 bits (112), Expect = 5e-05
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 10/196 (5%)
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
L + L + LEE L E D + N ++ + E +R L+S V++
Sbjct: 424 LQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQ 483
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+++ ++ E Q + + +K ++NEV TL+ LE K K QL + L
Sbjct: 484 IEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLK---KVSQNSQLANEKL 540
Query: 531 AKLQ-EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK--LEIN-VLE-EKQR 585
++LQ + +E D E + RL++++ +K I ++E ++ E N +LE K +
Sbjct: 541 SQLQKQLEEANDLLRTESDTAVRLRKSH--TEMSKSISQLESLNRELQERNRILENSKSQ 598
Query: 586 EEIKLYRLQLAQAAEK 601
+ Y+LQ AE+
Sbjct: 599 TDKDYYQLQAILEAER 614
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/221 (22%), Positives = 97/221 (43%), Gaps = 13/221 (5%)
Query: 299 ISKLREAWLRLTNSLDRAEDR-HRKALEKMICEVENFRVVADDAQKKTSHFESEL----- 352
I +L+ L LD AE + + L + + E + F + +++K S E+
Sbjct: 878 IQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELT-QESKKAASRNRQEITDKDH 936
Query: 353 -YKTLDLAHDYQDK-CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
L+ A+ K + L+ E + L E++ + + K++EI LK ++ +
Sbjct: 937 TVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKL---EKEEEISNLKAAFEKNIN 993
Query: 411 LNKQL-TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
+ L T V L E + ++ F D K+N +L K+ + L L QER+ V
Sbjct: 994 TERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVV 1053
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL 510
+ + ++ QL E+ +E+ + +++++ LR L
Sbjct: 1054 KHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKL 1094
Score = 37.1 bits (82), Expect = 0.20
Identities = 80/364 (21%), Positives = 158/364 (43%), Gaps = 35/364 (9%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKAL--------EKMICEVE-NFRVVADDAQKKTSH 347
A I+ L+E L ++L++ E ++A EK E++ N+++ + + +
Sbjct: 629 ARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEV 688
Query: 348 FESELYKT-LDLAHDYQDKCKQL---QNEKKSLEE-QLNTELDNVNVMLSNKDKEIDV-L 401
E ++ K L H ++ K + + EKK EE + + +N V + + +DV L
Sbjct: 689 NEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL 748
Query: 402 KENYDTVMRL--NKQ-LTDCVKNLEEALEKEK----FAHDSTKSNITELN--KRIQS-VN 451
K++ + L NK+ + D VKNL LE+E + K+ E + K ++ +
Sbjct: 749 KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMK 808
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
E L + + LL+ ++ + + E Q+ E Q+Q +VK L++ +E
Sbjct: 809 QEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIE 868
Query: 512 LQKNE-LKCHYQKQLEDAVLA------KLQEFQEQLDRAEREMENDARLKENNIVDSFNK 564
+ E LK + Q E LA + + EQL R E + +E+ S N+
Sbjct: 869 EKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR 928
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLH 624
Q + ++ + ++I++ R + + EK+ E + + ++ E + L
Sbjct: 929 QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKE---EEISNLK 985
Query: 625 AALQ 628
AA +
Sbjct: 986 AAFE 989
Score = 31.5 bits (68), Expect = 9.8
Identities = 53/286 (18%), Positives = 119/286 (41%), Gaps = 23/286 (8%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L KT+ + QL++E + N +LD + L + + L+ +
Sbjct: 425 QESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQI 484
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ---SVNDETLLLTQERDLLK 465
+ L + + E+E + ++ ++ L +++ V+ + L ++ L+
Sbjct: 485 EKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQ 544
Query: 466 SKVNEERSRCAVIEQ---QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-KCHY 521
++ E +L + + S+ + + + L+ E++ + LE K++ K +Y
Sbjct: 545 KQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY 604
Query: 522 QKQLEDAVLAKLQEFQEQLDRA-EREMENDARLKENNI---VDSFNKQILRIEEQHKLEI 577
Q Q A+L E+ DR + EM D + + ++ V + ++E + K
Sbjct: 605 QLQ---AILE-----AERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 656
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
++L ++E+ L + L KL L+ ++E + T ARL
Sbjct: 657 DMLNHSEKEKNNL-EIDLNY---KLKSLQQRLEQEVNEHKVTKARL 698
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 59.7 bits (138), Expect = 3e-08
Identities = 56/296 (18%), Positives = 131/296 (44%), Gaps = 16/296 (5%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+ ++K R+ +R T D+A ++ +K+ E+ +A+ E K
Sbjct: 332 KEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ---K 388
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
+ ++Q++ + Q ++L+++ + L +VL+ D + + +Q
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ 448
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
L + ++ ++ L + + A +++ EL + ++ + E LL + +V +
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
I+Q L + QN E+ K + ++ L++ + Q+N L L KL+
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSL-----------TLEKLK 557
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIK 589
L++ +R+ D K + ++ N ++ + E++ K ++ LE K++E E+K
Sbjct: 558 LAVADLEK-QRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYELK 612
Score = 56.4 bits (130), Expect = 3e-07
Identities = 66/290 (22%), Positives = 132/290 (45%), Gaps = 29/290 (10%)
Query: 308 RLTNSLDRAEDRH---RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
+L LD A++ + + ++ +I EVE+ + + ++ S ++++ L
Sbjct: 2483 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV----S 2538
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K Q++ E + +EQ N EL N+ V L K I VL+ ++ + L KNLE
Sbjct: 2539 KLSQVEGEHQLWKEQ-NLELRNLTVELEQK---IQVLQSKNASLQDTLEVLQSSYKNLEN 2594
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LE K S + ++ + + E + Q+ L+ +++ E++R A Q L E
Sbjct: 2595 ELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 2654
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLDR 542
+ + LK+ ++E+K L C ++ Q+ E V ++ E+Q +L
Sbjct: 2655 EIKSSKDQLKELTLENSELK----------KSLDCMHKDQVEKEGKVREEIAEYQLRLHE 2704
Query: 543 AEREMEN---DARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQRE 586
AE++ + D + + ++ +++ EE KLEI++L+ + E
Sbjct: 2705 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 2754
Score = 53.2 bits (122), Expect = 3e-06
Identities = 67/286 (23%), Positives = 134/286 (46%), Gaps = 22/286 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q+ TS ++ + +TL A + ++K QL N+K E+ EL N +L + KE+ +L
Sbjct: 888 QEDTSAHQNVVAETLS-ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL 946
Query: 402 -------KENYDTVMRLNK----QLTD---CVKNLEEALEKEKF-AHDSTKSNITELNKR 446
K+ +++ LNK +LT +K + +L +EK ++S +++R
Sbjct: 947 SETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDER 1006
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+S+++ + QE+ +L + E + + L +K E K + L NE +L
Sbjct: 1007 EKSISELSDQYKQEKLILLQRCEETGN----AYEDLSQKYKAAQEKNSKLECLLNECTSL 1062
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
++ + + +LK + K+ ++ L KL +E+ E+E + + + D+ N
Sbjct: 1063 CENRKNELEQLKEAFAKEHQE-FLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1121
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
K EI L+E+Q + K L + + + ++++K ECQ
Sbjct: 1122 SEAGGL-KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQ 1166
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 13/247 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDK-CKQLQNE-KKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+K S LY DL +K C + NE K+ + L EL V + E+D
Sbjct: 1909 EKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDT 1968
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ + + +L++++ + + LE + ++ + E + +Q+++ + L ++
Sbjct: 1969 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2028
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
+ L+ K+ + CE +NQ +++ K+ + L E ++L+ L E K +
Sbjct: 2029 KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLN 2087
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
K LE A++ K EF +L + E+ R K +RIE K ++++
Sbjct: 2088 VSKALEAALVEK-GEFALRLSSTQEEVHQLRR--------GIEKLRVRIEADEKKQLHIA 2138
Query: 581 EE-KQRE 586
E+ K+RE
Sbjct: 2139 EKLKERE 2145
Score = 50.4 bits (115), Expect = 2e-05
Identities = 74/307 (24%), Positives = 133/307 (43%), Gaps = 33/307 (10%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ V +A +AA+ + E LRL+++ + R+ +EK+ R+ AD+ KK H
Sbjct: 2086 LNVSKALEAALVEKGEFALRLSSTQEEVHQL-RRGIEKL-----RVRIEADE--KKQLHI 2137
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + +DK + L+ E + EE N EL V + N E++ LK + +
Sbjct: 2138 AEKLKERERENDSLKDKVENLERELQMSEE--NQEL--VILDAENSKAEVETLKTQIEEM 2193
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R K + L E + ++EL+K + S L +E++ + ++
Sbjct: 2194 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS----LLEEKEQAEIQI 2249
Query: 469 NEERSRCAVIEQQLCEKQNQC-------SEVLKKCD-FLD---NEVKTLRQHLELQKNEL 517
EE + Q ++ N+ E++K + LD E LR +E + L
Sbjct: 2250 KEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARL 2309
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKLE 576
+ +KQL VL +L+E + D + +EN R E + N++ +E E K E
Sbjct: 2310 EADEKKQL--CVLQQLKESEHHADLLKGRVENLERELE---IARTNQEHAALEAENSKGE 2364
Query: 577 INVLEEK 583
+ L+ K
Sbjct: 2365 VETLKAK 2371
Score = 46.4 bits (105), Expect = 3e-04
Identities = 74/346 (21%), Positives = 148/346 (42%), Gaps = 24/346 (6%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + + +R LTN L + ++R + LE + EN + + + S
Sbjct: 2380 RGLELDVVTIRSEKENLTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSSTA 2438
Query: 353 YKTLDLA-HDYQDKCKQLQNEK---KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L + ++ L N++ K+ E+ L+++++ + + + + +D K NY +
Sbjct: 2439 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2498
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L V++ ++ LEK+ K+ I + + + ++ + E L K +
Sbjct: 2499 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQN 2554
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
E R+ +EQ++ Q++ + + + L + K L LEL K + +K
Sbjct: 2555 LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK----- 2609
Query: 529 VLAKLQEFQEQLDRAEREM-ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
+ K+ + +L R EM + A L+E S K L E Q LE + Q +E
Sbjct: 2610 -VNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKE 2665
Query: 588 IKLYRLQLAQAAEKLGLLESKVECQRRRRGETA---ARLHAALQAH 630
+ L +L ++ + + + +VE + + R E A RLH A + H
Sbjct: 2666 LTLENSELKKSLDCMH--KDQVEKEGKVREEIAEYQLRLHEAEKKH 2709
Score = 42.7 bits (96), Expect = 0.004
Identities = 55/269 (20%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 327 MICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN 386
+I + E+F D+ +K S S+ YK L +C++ N + L ++ +
Sbjct: 992 LIQKSESFANYIDEREKSISEL-SDQYKQEKLI--LLQRCEETGNAYEDLSQKYKAAQEK 1048
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
N L E L EN + K+ K +E L K FA + ++ + EL
Sbjct: 1049 -NSKLECLLNECTSLCENRKNELEQLKEAF--AKEHQEFLTKLAFAEERNQNLMLELETV 1105
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
Q++ E +T ++ KS+ + ++++ + Q + +++L+ +NE
Sbjct: 1106 QQALRSE---MTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQ-----ENE---- 1153
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
Q +++ K + +C Q + + ++E + + ++ + + D +KE ++ DS+N Q+
Sbjct: 1154 -QLMKVMKTKHEC--QNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISL-DSYNAQL 1209
Query: 567 LRIEEQ-HKLEINVLEEKQREEIKLYRLQ 594
+++E E+ + E ++ +E + LQ
Sbjct: 1210 VQLEAMLRNKELKLQESEKEKECLQHELQ 1238
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/299 (21%), Positives = 131/299 (43%), Gaps = 50/299 (16%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL 384
EK++ ++E+ + ++ Q K +H E+ L +H+Y ++ + L+ ++ E L+ E+
Sbjct: 626 EKLLTQMESEK---ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR----ENLSVEI 678
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
N++ +L +K E++ K Y M L ++ + ++ +E + +L
Sbjct: 679 RNLHNVLDSKSVEVETQKLAY---MELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLE 735
Query: 445 KRIQSVNDETL---LLTQE--------RDLLKSK-----VNEERSRCAV-IEQQ------ 481
++Q +++E + Q+ RDLLKSK NE+ R + +QQ
Sbjct: 736 HKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHS 795
Query: 482 ----------LCEKQNQC----SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++++C + K L N V +L LE QK ++ QKQ E+
Sbjct: 796 FANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK-QMNSDLQKQCEE 854
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
V K E +E L +AE +M + + + + + ++ LE K++E
Sbjct: 855 LVQIK-GEIEENLMKAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 911
Score = 39.5 bits (88), Expect = 0.037
Identities = 58/291 (19%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 325 EKMICEVENFRVVADDA--QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT 382
E+ C +E + + A Q + E L + D Q +C++L K +EE L
Sbjct: 809 ERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMK 868
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
++ + I L+E+ + + ++N E+ L+ ++ ++ I E
Sbjct: 869 AEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 928
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
L K + D L + L S +E S + ++ E+ Q + LK+ + N+
Sbjct: 929 LKKSNHLLEDSLKELQLLSETL-SLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQ 987
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ----LDRAER--------EMEND 550
K +L +QK+E +Y + E ++ +++++ L R E +
Sbjct: 988 EK---MNL-IQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1043
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
A ++N+ ++ + + E K E+ L+E +E + + +LA A E+
Sbjct: 1044 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1094
Score = 37.9 bits (84), Expect = 0.11
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 13/179 (7%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D KQ + E ++ E+L ++ + LS++ EID+LK + + LN L + LE
Sbjct: 2715 DTNKQYEVEIQTYREKLTSKEE----CLSSQKLEIDLLKSSKE---ELNNSLKATTQILE 2767
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E L+K K + + + + N+R Q + ++ + K + +E S+ +
Sbjct: 2768 E-LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ---- 2822
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLD 541
EKQ + + K D L E+K L++ LE + E + K + KL++ +E L+
Sbjct: 2823 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2881
>BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein
protein.
Length = 971
Score = 59.7 bits (138), Expect = 3e-08
Identities = 83/384 (21%), Positives = 174/384 (45%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 340 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 399
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++L+T E+ ++ M+ ++ +
Sbjct: 400 KLNLEEDKNQLQQELENLKEVLEDKLDTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 459
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 460 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 519
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 520 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 579
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 580 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 638
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E L + +E +++ R + +
Sbjct: 639 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGLRIEMEQELQTLRFELEDEGKAM 697
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 698 LASLRSELNHQHAAAIDLLRHNHH 721
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 132/297 (44%), Gaps = 28/297 (9%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQ-------NEKKSLEEQLNTELDNVNVMLSNK 394
+K ++EL D A DKC++LQ N + L++QL+ + +LS K
Sbjct: 179 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLS-K 237
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEA--LEKEKFAHDSTKSNITELNKRIQSVND 452
KE++ E RL +Q +D V L+ + + T I +L VN+
Sbjct: 238 HKEVE--SELAAARERLQQQASDLVLKASHIGMLQATQMTQEVT---IKDLESEKSRVNE 292
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQHLE 511
L +ER L+SK +S +QQ+ E + + +E + + ++ + E+K L+ LE
Sbjct: 293 RLSQLEEERAFLRSKT---QSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLE 349
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ +L + K LE+ + A R D + + ++ + NK L +EE
Sbjct: 350 EEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIR----DKKKLQMDLEEQHNKDKLNLEE 405
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ N L+++ ++ +L A +++G L+ V + G +A L A+LQ
Sbjct: 406 ----DKNQLQQELENLKEVLEDKLDTANQEIGHLQDMVRKSEQGLG-SAEGLIASLQ 457
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 59.7 bits (138), Expect = 3e-08
Identities = 83/357 (23%), Positives = 163/357 (45%), Gaps = 43/357 (12%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD-DAQKKTSHFESELYK 354
D A+ +LR++ ++ S+ + E +R+ E+ +EN + D D + + E+E
Sbjct: 559 DTAV-RLRKSHTEMSKSISQLESLNRELQERNRI-LENSKSQTDKDYYQLQAILEAE--- 613
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
D HD + LQ SL+E++ N+ + + + D+L + L
Sbjct: 614 RRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID 672
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL-----LTQERDL---LKS 466
L +K+L++ LE+E H TK+ +T+ ++ I+ + L +ER+ ++
Sbjct: 673 LNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAEN 732
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-------LQKNELKC 519
+V + +C++++ L + Q + + + +++EVK L LE L +NELK
Sbjct: 733 RVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKT 792
Query: 520 H---------YQKQLEDAV-----LAKLQEFQ-EQLDRAEREMENDAR-LKENNIVDSFN 563
+KQ++ + +L EF+ QL + R E R L++ + +
Sbjct: 793 QAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYF 852
Query: 564 KQILRIEEQHKLEINVLEEKQREEI-KLYRLQLAQ--AAEKLGLLESKVECQRRRRG 617
+ + + + E +EEK RE + K+ LQ + A +L L E+K E ++ RG
Sbjct: 853 STLYKTQVKELKE--EIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARG 907
Score = 54.8 bits (126), Expect = 9e-07
Identities = 82/356 (23%), Positives = 165/356 (46%), Gaps = 46/356 (12%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDR--HRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
KD K R + ++L + ++ R+ LE + ++E +++ Q + + ++ +
Sbjct: 446 KDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLL---QHRINEYQRKA 502
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEI--DVLKENYDTVM 409
+ + + +++ L+N+ + L++ N++L N + K E D+L+ DT +
Sbjct: 503 EQENEKRRNVENEVSTLKNQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAV 562
Query: 410 RLNKQLTDCVKNLE--EALEKEKFAH----DSTKSN----------ITELNKRIQSVNDE 453
RL K T+ K++ E+L +E +++KS I E +R + + E
Sbjct: 563 RLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSE 622
Query: 454 TLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV----KTLRQ 508
+ Q R L+ +V + +E + E Q+ + K+ + L+ ++ K+L+Q
Sbjct: 623 MIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQ 682
Query: 509 HLELQKNELKC------HYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
LE + NE K + +E+A + E +++L + ERE AR K N V
Sbjct: 683 RLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL-KEERE----AREKAENRVVQI 737
Query: 563 NKQILRIE-----EQHKLE-INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
KQ ++ Q KLE + +E+ +E+K LQL Q + K LL+++++ Q
Sbjct: 738 EKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQ 793
Score = 51.6 bits (118), Expect = 9e-06
Identities = 70/324 (21%), Positives = 139/324 (42%), Gaps = 31/324 (9%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++ AK A+ ++ + + ++AE+R + +EK ++ V +Q+K H
Sbjct: 705 IEEAKSVAMCEMEKKLKEEREAREKAENRVVQ-IEKQCSMLD---VDLKQSQQKLEHLTG 760
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEIDVLKENYDT 407
+ D + + +Q N++ L+ +L T E DN+ + +EI+ L E
Sbjct: 761 NKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRL 820
Query: 408 V----MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +L KQ ++ L++ LE E++ K+ + EL + I+ N E L QE
Sbjct: 821 LEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQE 880
Query: 461 R-----------DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
DL ++K E+ ++E+Q E ++ KK + + T + H
Sbjct: 881 LQNEKETLATQLDLAETKAESEQLARGLLEEQYFE----LTQESKKAASRNRQEITDKDH 936
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+ E K +E + + +E E++ +AE E + + + +N+ +F K I
Sbjct: 937 TVSRLEEANSMLTKDIE-ILRRENEELTERMKKAEEEYKLEKEEEISNLKAAFEKNINTE 995
Query: 570 EEQHKLEINVLEE-KQREEIKLYR 592
+N L E R++ K+ R
Sbjct: 996 RTLKTQAVNKLAEIMNRKDFKIDR 1019
Score = 49.2 bits (112), Expect = 5e-05
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 10/196 (5%)
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
L + L + LEE L E D + N ++ + E +R L+S V++
Sbjct: 424 LQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQ 483
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+++ ++ E Q + + +K ++NEV TL+ LE K K QL + L
Sbjct: 484 IEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLK---KVSQNSQLANEKL 540
Query: 531 AKLQ-EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK--LEIN-VLE-EKQR 585
++LQ + +E D E + RL++++ +K I ++E ++ E N +LE K +
Sbjct: 541 SQLQKQLEEANDLLRTESDTAVRLRKSH--TEMSKSISQLESLNRELQERNRILENSKSQ 598
Query: 586 EEIKLYRLQLAQAAEK 601
+ Y+LQ AE+
Sbjct: 599 TDKDYYQLQAILEAER 614
Score = 44.8 bits (101), Expect = 0.001
Identities = 49/221 (22%), Positives = 97/221 (43%), Gaps = 13/221 (5%)
Query: 299 ISKLREAWLRLTNSLDRAEDR-HRKALEKMICEVENFRVVADDAQKKTSHFESEL----- 352
I +L+ L LD AE + + L + + E + F + +++K S E+
Sbjct: 878 IQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELT-QESKKAASRNRQEITDKDH 936
Query: 353 -YKTLDLAHDYQDK-CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
L+ A+ K + L+ E + L E++ + + K++EI LK ++ +
Sbjct: 937 TVSRLEEANSMLTKDIEILRRENEELTERMKKAEEEYKL---EKEEEISNLKAAFEKNIN 993
Query: 411 LNKQL-TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
+ L T V L E + ++ F D K+N +L K+ + L L QER+ V
Sbjct: 994 TERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVV 1053
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL 510
+ + ++ QL E+ +E+ + +++++ LR L
Sbjct: 1054 KHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKL 1094
Score = 31.9 bits (69), Expect = 7.4
Identities = 53/286 (18%), Positives = 119/286 (41%), Gaps = 23/286 (8%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L KT+ + QL++E + N +LD + L + + L+ +
Sbjct: 425 QESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQI 484
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ---SVNDETLLLTQERDLLK 465
+ L + + E+E + ++ ++ L +++ V+ + L ++ L+
Sbjct: 485 EKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLKKVSQNSQLANEKLSQLQ 544
Query: 466 SKVNEERSRCAVIEQ---QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-KCHY 521
++ E +L + + S+ + + + L+ E++ + LE K++ K +Y
Sbjct: 545 KQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY 604
Query: 522 QKQLEDAVLAKLQEFQEQLDRA-EREMENDARLKENNI---VDSFNKQILRIEEQHKLEI 577
Q Q A+L E+ DR + EM D + + ++ V + ++E + K
Sbjct: 605 QLQ---AILE-----AERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 656
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
++L ++E+ L + L KL L+ ++E + T ARL
Sbjct: 657 DMLNHSEKEKNNL-EIDLNY---KLKSLQQRLEQEVNEHKVTKARL 698
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 59.7 bits (138), Expect = 3e-08
Identities = 67/306 (21%), Positives = 148/306 (48%), Gaps = 26/306 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
A ++ R AL+ + E E R + +K +H E++L K + + Q + +Q EK+
Sbjct: 635 AAEQARNALQVDLAEAEKRR---EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEE 691
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDS 435
++++L+ ++ L++ + R + L V+ +EAL +EK A
Sbjct: 692 IQKKLSES-------RHQQEAATTQLEQLHQEAKRQEEVLARAVQE-KEALVREKAA--- 740
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + + + Q + ++ L+ ++LL+S + E + + +VIE + + Q V +
Sbjct: 741 LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQA 800
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
+ + EV+ L+ L+ ++++ +Q DA +L + EQ + E + A KE
Sbjct: 801 KEVIQGEVRCLKLELDTERSQ-----AEQERDAAARQLAQ-AEQEGKTALEQQKAAHEKE 854
Query: 556 -NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
N + + + K+ R Q +L LE +RE+++L ++L + ++ ++++ E + R
Sbjct: 855 VNQLREKWEKE--RSWHQQEL-AKALESLEREKMEL-EMRLKEQQTEMEAIQAQRE-EER 909
Query: 615 RRGETA 620
+ E+A
Sbjct: 910 TQAESA 915
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/265 (23%), Positives = 116/265 (43%), Gaps = 20/265 (7%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLEEALE 427
+Q E + L+ +L+TE +++ ++ T + K + V L E E
Sbjct: 804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWE 863
Query: 428 KEKFAHDSTKSNITELNKRIQSVNDETLLLTQ-ERDLLKSKVNEERSRC--AVIEQQLCE 484
KE+ H + E +R + + L Q E + ++++ EER++ A+ + QL E
Sbjct: 864 KERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQL-E 922
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKLQEFQEQLDR 542
+ + +L+ E+ Q LE + ++K K+ E + +LQE Q +L
Sbjct: 923 TEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982
Query: 543 AEREMEND-ARLKENNI------------VDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A R+ +D A L+E + V+ Q++ ++ +L ++EK RE +
Sbjct: 983 AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQE 1042
Query: 590 LYRLQLAQAAEKLGLLESKVECQRR 614
R+Q EK L S +E ++R
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQR 1067
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/268 (19%), Positives = 114/268 (42%), Gaps = 10/268 (3%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNL 422
Q + ++ + + + E+ L ++LD L+ +D+E++ L++ +++ + L
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ ALE+ + + ++ + + +E + + L+ + + R+ E+ L
Sbjct: 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1903
Query: 483 CEKQNQCSEVLKKCDFLDNEVKT-LRQHLELQKNELKCHYQKQLEDAVLAKLQ--EFQEQ 539
Q QC+E + ++EV+T Q LQ + ++LE A+ A+ Q QE+
Sbjct: 1904 LALQQQCAEQAQ-----EHEVETRALQDSWLQAQAVLKERDQELE-ALRAESQSSRHQEE 1957
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
RA E +A K + + + +L E + + + + + Q
Sbjct: 1958 AARARAEALQEALGKAHAALQGKEQHLLEQAELSR-SLEASTATLQASLDACQAHSRQLE 2016
Query: 600 EKLGLLESKVECQRRRRGETAARLHAAL 627
E L + E +++ Q R E +L AL
Sbjct: 2017 EALRIQEGEIQDQDLRYQEDVQQLQQAL 2044
Score = 46.0 bits (104), Expect = 4e-04
Identities = 70/336 (20%), Positives = 143/336 (42%), Gaps = 29/336 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVV-ADDAQKKTSHFES-ELYKTLDLAHDYQDKCKQL 369
SL R + +L+++I ++ V D+ + + H S EL ++ DYQD K L
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKAL 388
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+ L + D + L+ + +++L++ +D Q + K L + L+K
Sbjct: 389 TLVRSVLTRRRQAVQD-LRQQLAGCQEAVNLLQQQHD-------QWEEEGKALRQRLQKL 440
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
D+ +L + S L++ER+LL+ E R + V+EQ+ +
Sbjct: 441 TGERDTLAGQTVDLQGEVDS-------LSKERELLQKAREELRQQLEVLEQEAWRLRRVN 493
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL------EDAVLAKLQEFQEQLDRA 543
E+ + D + + ++ L L E + Q+ L + L++L +E L+ +
Sbjct: 494 VELQLQGDSAQGQKEEQQEELHLAVRERE-RLQEMLMGLEAKQSESLSELITLREALESS 552
Query: 544 --EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
E E+ + + + + I + + + + +KL L A A +K
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDK 612
Query: 602 LGLLESKVECQRRRRGETAARLHAALQAHWRHALRI 637
+GL + ++ + + +R+ AA QA R+AL++
Sbjct: 613 VGLNQQLLQLEEENQ-SVCSRMEAAEQA--RNALQV 645
Score = 45.2 bits (102), Expect = 7e-04
Identities = 82/382 (21%), Positives = 159/382 (41%), Gaps = 35/382 (9%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMI-CEVENFRVVAD--DAQKKTSHFESELY 353
+A+ KL + + + D D+ +K E++ E E +V + D Q++ S + E
Sbjct: 1243 SALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLN-TELDNVNVMLSNKDKEIDVLKENYDT-VMRL 411
K + + + +L SL+ +L EL + + + + KEN V L
Sbjct: 1303 KWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ--GERELLQAAKENLTAQVEHL 1360
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ + A E+ + +S + N+ ++S + L ++ +L ++
Sbjct: 1361 QAAVVEARAQASAAGILEEDLR-TARSALKLKNEEVESERERAQALQEQGELKVAQGKAL 1419
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ----KQLED 527
+ A++ Q L E++ + + + L+ + + + LEL +LK Q +Q +
Sbjct: 1420 QENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQRE 586
L K + E L A +E E ++ I + K R +++ LE +LE EK+ +
Sbjct: 1480 QELEKCRSVLEHLPMAVQEREQKLTVQREQIRE-LEKD--RETQRNVLEHQLLELEKKDQ 1536
Query: 587 EIKLYRLQLAQAAEKLGLLE----------SKVECQRR--------RRGETAARLHAALQ 628
I+ R Q+ ++L LE K+ECQ++ R + A H L
Sbjct: 1537 MIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLD 1596
Query: 629 AHWR-HALRILAAPHHDLGTHS 649
R L+ ++ HDL +HS
Sbjct: 1597 LEERSQELQAQSSQIHDLESHS 1618
Score = 36.7 bits (81), Expect = 0.26
Identities = 46/239 (19%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++R K +L+E + ++ + R E +C+++ + +++ S E+
Sbjct: 880 LEREKMELEMRLKEQQTEM-EAIQAQREEERTQAESALCQMQ-----LETEKERVSLLET 933
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKK--SLEEQ-----LNTELDNVNVMLSNKDKE----ID 399
L +LA D + ++L+ + K L+EQ L T+L L ++ +
Sbjct: 934 LLQTQKELA-DASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLA 992
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L+E ++++ L V++L+ L + + + + E + Q N L +
Sbjct: 993 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELER 1052
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
E+ L + E+ R V+++ +Q + S + + E K L +EL + E+K
Sbjct: 1053 EKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal
Nek2-associated protein 1 protein.
Length = 2442
Score = 59.7 bits (138), Expect = 3e-08
Identities = 67/306 (21%), Positives = 148/306 (48%), Gaps = 26/306 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
A ++ R AL+ + E E R + +K +H E++L K + + Q + +Q EK+
Sbjct: 635 AAEQARNALQVDLAEAEKRR---EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEE 691
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDS 435
++++L+ ++ L++ + R + L V+ +EAL +EK A
Sbjct: 692 IQKKLSES-------RHQQEAATTQLEQLHQEAKRQEEVLARAVQE-KEALVREKAA--- 740
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + + + Q + ++ L+ ++LL+S + E + + +VIE + + Q V +
Sbjct: 741 LEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQA 800
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
+ + EV+ L+ L+ ++++ +Q DA +L + EQ + E + A KE
Sbjct: 801 KEVIQGEVRCLKLELDTERSQ-----AEQERDAAARQLAQ-AEQEGKTALEQQKAAHEKE 854
Query: 556 -NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
N + + + K+ R Q +L LE +RE+++L ++L + ++ ++++ E + R
Sbjct: 855 VNQLREKWEKE--RSWHQQEL-AKALESLEREKMEL-EMRLKEQQTEMEAIQAQRE-EER 909
Query: 615 RRGETA 620
+ E+A
Sbjct: 910 TQAESA 915
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/265 (23%), Positives = 116/265 (43%), Gaps = 20/265 (7%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLEEALE 427
+Q E + L+ +L+TE +++ ++ T + K + V L E E
Sbjct: 804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWE 863
Query: 428 KEKFAHDSTKSNITELNKRIQSVNDETLLLTQ-ERDLLKSKVNEERSRC--AVIEQQLCE 484
KE+ H + E +R + + L Q E + ++++ EER++ A+ + QL E
Sbjct: 864 KERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQL-E 922
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKLQEFQEQLDR 542
+ + +L+ E+ Q LE + ++K K+ E + +LQE Q +L
Sbjct: 923 TEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982
Query: 543 AEREMEND-ARLKENNI------------VDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A R+ +D A L+E + V+ Q++ ++ +L ++EK RE +
Sbjct: 983 AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQE 1042
Query: 590 LYRLQLAQAAEKLGLLESKVECQRR 614
R+Q EK L S +E ++R
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQR 1067
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/268 (19%), Positives = 114/268 (42%), Gaps = 10/268 (3%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNL 422
Q + ++ + + + E+ L ++LD L+ +D+E++ L++ +++ + L
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ ALE+ + + ++ + + +E + + L+ + + R+ E+ L
Sbjct: 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1903
Query: 483 CEKQNQCSEVLKKCDFLDNEVKT-LRQHLELQKNELKCHYQKQLEDAVLAKLQ--EFQEQ 539
Q QC+E + ++EV+T Q LQ + ++LE A+ A+ Q QE+
Sbjct: 1904 LALQQQCAEQAQ-----EHEVETRALQDSWLQAQAVLKERDQELE-ALRAESQSSRHQEE 1957
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
RA E +A K + + + +L E + + + + + Q
Sbjct: 1958 AARARAEALQEALGKAHAALQGKEQHLLEQAELSR-SLEASTATLQASLDACQAHSRQLE 2016
Query: 600 EKLGLLESKVECQRRRRGETAARLHAAL 627
E L + E +++ Q R E +L AL
Sbjct: 2017 EALRIQEGEIQDQDLRYQEDVQQLQQAL 2044
Score = 46.0 bits (104), Expect = 4e-04
Identities = 70/336 (20%), Positives = 143/336 (42%), Gaps = 29/336 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVV-ADDAQKKTSHFES-ELYKTLDLAHDYQDKCKQL 369
SL R + +L+++I ++ V D+ + + H S EL ++ DYQD K L
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKAL 388
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+ L + D + L+ + +++L++ +D Q + K L + L+K
Sbjct: 389 TLVRSVLTRRRQAVQD-LRQQLAGCQEAVNLLQQQHD-------QWEEEGKALRQRLQKL 440
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
D+ +L + S L++ER+LL+ E R + V+EQ+ +
Sbjct: 441 TGERDTLAGQTVDLQGEVDS-------LSKERELLQKAREELRQQLEVLEQEAWRLRRVN 493
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL------EDAVLAKLQEFQEQLDRA 543
E+ + D + + ++ L L E + Q+ L + L++L +E L+ +
Sbjct: 494 VELQLQGDSAQGQKEDQQEELHLAVRERE-RLQEMLMGLEAKQSESLSELITLREALESS 552
Query: 544 --EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
E E+ + + + + I + + + + +KL L A A +K
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDK 612
Query: 602 LGLLESKVECQRRRRGETAARLHAALQAHWRHALRI 637
+GL + ++ + + +R+ AA QA R+AL++
Sbjct: 613 VGLNQQLLQLEEENQ-SVCSRMEAAEQA--RNALQV 645
Score = 45.2 bits (102), Expect = 7e-04
Identities = 82/382 (21%), Positives = 159/382 (41%), Gaps = 35/382 (9%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMI-CEVENFRVVAD--DAQKKTSHFESELY 353
+A+ KL + + + D D+ +K E++ E E +V + D Q++ S + E
Sbjct: 1243 SALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLN-TELDNVNVMLSNKDKEIDVLKENYDT-VMRL 411
K + + + +L SL+ +L EL + + + + KEN V L
Sbjct: 1303 KWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ--GERELLQAAKENLTAQVEHL 1360
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ + A E+ + +S + N+ ++S + L ++ +L ++
Sbjct: 1361 QAAVVEARAQASAAGILEEDLR-TARSALKLKNEEVESERERAQALQEQGELKVAQGKAL 1419
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ----KQLED 527
+ A++ Q L E++ + + + L+ + + + LEL +LK Q +Q +
Sbjct: 1420 QENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQRE 586
L K + E L A +E E ++ I + K R +++ LE +LE EK+ +
Sbjct: 1480 QELEKCRSVLEHLPMAVQEREQKLTVQREQIRE-LEKD--RETQRNVLEHQLLELEKKDQ 1536
Query: 587 EIKLYRLQLAQAAEKLGLLE----------SKVECQRR--------RRGETAARLHAALQ 628
I+ R Q+ ++L LE K+ECQ++ R + A H L
Sbjct: 1537 MIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLD 1596
Query: 629 AHWR-HALRILAAPHHDLGTHS 649
R L+ ++ HDL +HS
Sbjct: 1597 LEERSQELQAQSSQIHDLESHS 1618
Score = 36.7 bits (81), Expect = 0.26
Identities = 46/239 (19%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++R K +L+E + ++ + R E +C+++ + +++ S E+
Sbjct: 880 LEREKMELEMRLKEQQTEM-EAIQAQREEERTQAESALCQMQ-----LETEKERVSLLET 933
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKK--SLEEQ-----LNTELDNVNVMLSNKDKE----ID 399
L +LA D + ++L+ + K L+EQ L T+L L ++ +
Sbjct: 934 LLQTQKELA-DASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLA 992
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L+E ++++ L V++L+ L + + + + E + Q N L +
Sbjct: 993 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELER 1052
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
E+ L + E+ R V+++ +Q + S + + E K L +EL + E+K
Sbjct: 1053 EKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 59.7 bits (138), Expect = 3e-08
Identities = 83/357 (23%), Positives = 163/357 (45%), Gaps = 43/357 (12%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD-DAQKKTSHFESELYK 354
D A+ +LR++ ++ S+ + E +R+ E+ +EN + D D + + E+E
Sbjct: 237 DTAV-RLRKSHTEMSKSISQLESLNRELQERNRI-LENSKSQTDKDYYQLQAILEAE--- 291
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
D HD + LQ SL+E++ N+ + + + D+L + L
Sbjct: 292 RRDRGHD-SEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEID 350
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL-----LTQERDL---LKS 466
L +K+L++ LE+E H TK+ +T+ ++ I+ + L +ER+ ++
Sbjct: 351 LNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAEN 410
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-------LQKNELKC 519
+V + +C++++ L + Q + + + +++EVK L LE L +NELK
Sbjct: 411 RVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKT 470
Query: 520 H---------YQKQLEDAV-----LAKLQEFQ-EQLDRAEREMENDAR-LKENNIVDSFN 563
+KQ++ + +L EF+ QL + R E R L++ + +
Sbjct: 471 QAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYF 530
Query: 564 KQILRIEEQHKLEINVLEEKQREEI-KLYRLQLAQ--AAEKLGLLESKVECQRRRRG 617
+ + + + E +EEK RE + K+ LQ + A +L L E+K E ++ RG
Sbjct: 531 STLYKTQVKELKE--EIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARG 585
Score = 56.0 bits (129), Expect = 4e-07
Identities = 79/315 (25%), Positives = 143/315 (45%), Gaps = 35/315 (11%)
Query: 325 EKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQ--DKCKQLQNEKKSLEEQL 380
EKM+ + + ++ A+ +K + E+E+ D D + + QL NEK S QL
Sbjct: 165 EKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLS---QL 221
Query: 381 NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA---LEKEKFAHDSTK 437
+L+ N +L + L++++ + + QL + L+E LE K D
Sbjct: 222 QKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDY 281
Query: 438 SN---ITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
I E +R + + E + Q R L+ +V + +E + E Q+ +
Sbjct: 282 YQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSE 341
Query: 494 KKCDFLDNEV----KTLRQHLELQKNELKC------HYQKQLEDAVLAKLQEFQEQLDRA 543
K+ + L+ ++ K+L+Q LE + NE K + +E+A + E +++L +
Sbjct: 342 KEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL-KE 400
Query: 544 EREMENDARLKENNIVDSFNKQILRIE-----EQHKLE-INVLEEKQREEIKLYRLQLAQ 597
ERE AR K N V KQ ++ Q KLE + +E+ +E+K LQL Q
Sbjct: 401 ERE----AREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQ 456
Query: 598 AAEKLGLLESKVECQ 612
+ K LL+++++ Q
Sbjct: 457 ESNKRLLLQNELKTQ 471
Score = 51.6 bits (118), Expect = 9e-06
Identities = 70/324 (21%), Positives = 139/324 (42%), Gaps = 31/324 (9%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++ AK A+ ++ + + ++AE+R + +EK ++ V +Q+K H
Sbjct: 383 IEEAKSVAMCEMEKKLKEEREAREKAENRVVQ-IEKQCSMLD---VDLKQSQQKLEHLTG 438
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEIDVLKENYDT 407
+ D + + +Q N++ L+ +L T E DN+ + +EI+ L E
Sbjct: 439 NKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRL 498
Query: 408 V----MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +L KQ ++ L++ LE E++ K+ + EL + I+ N E L QE
Sbjct: 499 LEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQE 558
Query: 461 R-----------DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
DL ++K E+ ++E+Q E ++ KK + + T + H
Sbjct: 559 LQNEKETLATQLDLAETKAESEQLARGLLEEQYFE----LTQESKKAASRNRQEITDKDH 614
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+ E K +E + + +E E++ +AE E + + + +N+ +F K I
Sbjct: 615 TVSRLEEANSMLTKDIE-ILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTE 673
Query: 570 EEQHKLEINVLEE-KQREEIKLYR 592
+N L E R++ K+ R
Sbjct: 674 RTLKTQAVNKLAEIMNRKDFKIDR 697
Score = 49.2 bits (112), Expect = 5e-05
Identities = 49/196 (25%), Positives = 90/196 (45%), Gaps = 10/196 (5%)
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
L + L + LEE L E D + N ++ + E +R L+S V++
Sbjct: 102 LQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQ 161
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+++ ++ E Q + + +K ++NEV TL+ LE K K QL + L
Sbjct: 162 IEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLK---KVSQNSQLANEKL 218
Query: 531 AKLQ-EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK--LEIN-VLE-EKQR 585
++LQ + +E D E + RL++++ +K I ++E ++ E N +LE K +
Sbjct: 219 SQLQKQLEEANDLLRTESDTAVRLRKSH--TEMSKSISQLESLNRELQERNRILENSKSQ 276
Query: 586 EEIKLYRLQLAQAAEK 601
+ Y+LQ AE+
Sbjct: 277 TDKDYYQLQAILEAER 292
Score = 37.1 bits (82), Expect = 0.20
Identities = 80/364 (21%), Positives = 158/364 (43%), Gaps = 35/364 (9%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKAL--------EKMICEVE-NFRVVADDAQKKTSH 347
A I+ L+E L ++L++ E ++A EK E++ N+++ + + +
Sbjct: 307 ARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEV 366
Query: 348 FESELYKT-LDLAHDYQDKCKQL---QNEKKSLEE-QLNTELDNVNVMLSNKDKEIDV-L 401
E ++ K L H ++ K + + EKK EE + + +N V + + +DV L
Sbjct: 367 NEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDL 426
Query: 402 KENYDTVMRL--NKQ-LTDCVKNLEEALEKEK----FAHDSTKSNITELN--KRIQS-VN 451
K++ + L NK+ + D VKNL LE+E + K+ E + K ++ +
Sbjct: 427 KQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMK 486
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
E L + + LL+ ++ + + E Q+ E Q+Q +VK L++ +E
Sbjct: 487 QEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIE 546
Query: 512 LQKNE-LKCHYQKQLEDAVLA------KLQEFQEQLDRAEREMENDARLKENNIVDSFNK 564
+ E LK + Q E LA + + EQL R E + +E+ S N+
Sbjct: 547 EKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNR 606
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLH 624
Q + ++ + ++I++ R + + EK+ E + + ++ E + L
Sbjct: 607 QEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKE---EEISNLK 663
Query: 625 AALQ 628
AA +
Sbjct: 664 AAFE 667
Score = 31.5 bits (68), Expect = 9.8
Identities = 53/286 (18%), Positives = 119/286 (41%), Gaps = 23/286 (8%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L KT+ + QL++E + N +LD + L + + L+ +
Sbjct: 103 QESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQI 162
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ---SVNDETLLLTQERDLLK 465
+ L + + E+E + ++ ++ L +++ V+ + L ++ L+
Sbjct: 163 EKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQ 222
Query: 466 SKVNEERSRCAVIEQ---QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-KCHY 521
++ E +L + + S+ + + + L+ E++ + LE K++ K +Y
Sbjct: 223 KQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYY 282
Query: 522 QKQLEDAVLAKLQEFQEQLDRA-EREMENDARLKENNI---VDSFNKQILRIEEQHKLEI 577
Q Q A+L E+ DR + EM D + + ++ V + ++E + K
Sbjct: 283 QLQ---AILE-----AERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ 334
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARL 623
++L ++E+ L + L KL L+ ++E + T ARL
Sbjct: 335 DMLNHSEKEKNNL-EIDLNY---KLKSLQQRLEQEVNEHKVTKARL 376
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 59.3 bits (137), Expect = 4e-08
Identities = 85/348 (24%), Positives = 151/348 (43%), Gaps = 29/348 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A +++V +K+ A+ L++ +L L+ K LE V + R+ D QKK+
Sbjct: 737 ADSLEVKASKEQALQDLQQQ-RQLNTDLELRATELSKQLEMEKEIVSSTRL---DLQKKS 792
Query: 346 SHFES---ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
ES +L K + + + L E K E+LN + L E + L
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 403 ENYDTVMRLNKQLTDCVKNLEEALEKE----KFAHDSTKSNITELNKRIQSVNDETLLLT 458
TV +++D +KN + EKE K A + EL ++Q + T L
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENT--LK 910
Query: 459 QERDLLKSKVNEERSRCAV------IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL 512
++++L KS E+ + + +++QL + QN + K+ L + L+Q E
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQ 970
Query: 513 QKNELKCHYQKQLEDAVLAKLQ---EFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+K +++ Q +L+ AVL K + + Q+QL +A +E+ A KE V N + +
Sbjct: 971 KKKQIEA-LQGELKIAVLQKTELENKLQQQLTQAAQEL---AAEKEKISVLQNNYE--KS 1024
Query: 570 EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E K ++ + E+ R L EKL L + + R + G
Sbjct: 1025 QETFK-QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIG 1071
Score = 56.4 bits (130), Expect = 3e-07
Identities = 69/330 (20%), Positives = 149/330 (45%), Gaps = 25/330 (7%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE--- 351
+ + +KLREA L L + D+ +K ++N + +++ S E E
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGDKDQK--------IQNLEALLQKSKENISLLEKERED 548
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN-YDTVMR 410
LY + QLQ + +L+EQ+ T+L L N+ + +EN +D V
Sbjct: 549 LYAKIQAGEGETAVLNQLQEKNHTLQEQV-TQLTE---KLKNQSESHKQAQENLHDQVQE 604
Query: 411 LNKQLT---DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
L D V +LE ++ + + +K +++L+ +I++ + LLL+ E +
Sbjct: 605 QKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTE--LLLSAEAAKTAQR 662
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ + + + L +KQ + +++ + D + +++ ++H ++ LK + +K L
Sbjct: 663 ADLQ-NHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYL-- 719
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKLEINVLEEKQRE 586
++ K +E + Q+ + E + KE + D ++ L + E E++ E ++E
Sbjct: 720 SLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKE 779
Query: 587 EIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+ RL L + +E L ++ K+ Q +
Sbjct: 780 IVSSTRLDLQKKSEALESIKQKLTKQEEEK 809
Score = 48.4 bits (110), Expect = 8e-05
Identities = 70/315 (22%), Positives = 144/315 (45%), Gaps = 36/315 (11%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS-LEEQLNT 382
LE+ E N + + D ++K + +E+ + +D + ++ +K + L E+LN
Sbjct: 144 LEEAQTENFNIKQMKDLFEQKAAQLATEI-ADIKSKYDEERSLREAAEQKVTRLTEELNK 202
Query: 383 E---LDNVNVMLSNKD--KEIDVLKENYDTVMRLNKQLT----DCVKNLEEALEKEKFAH 433
E + ++ L + +++ VLK+ V L +T + L++ +K + +
Sbjct: 203 EATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQY 262
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
S+++ I++L + E + QE LKS VNE + + + L +K+ +++
Sbjct: 263 ASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE 322
Query: 494 KKCDFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDA 551
+K NE +++++ L + +L C +QL+ ++L + L R E+
Sbjct: 323 EK----HNEESVSKKNIQATLHQKDLDC---QQLQ----SRLSASETSLHRIHVELS--- 368
Query: 552 RLKENNIVDSFNKQILRIEE--QH-KLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
++ +++ +E QH K E L++ QREE + + LQL ++ L SK
Sbjct: 369 --EKGEATQKLKEELSEVETKYQHLKAEFKQLQQ-QREEKEQHGLQL---QSEINQLHSK 422
Query: 609 VECQRRRRGETAARL 623
+ R+ GE RL
Sbjct: 423 LLETERQLGEAHGRL 437
Score = 48.4 bits (110), Expect = 8e-05
Identities = 57/296 (19%), Positives = 130/296 (43%), Gaps = 12/296 (4%)
Query: 337 VADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK 396
V+D + S FE E K D + CK+L+++ + E E + L + +
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL 456
LK +++ Q + +K E+ ++ + + K + + K+I+++ E +
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++ L++K+ ++ ++ A Q+L ++ + S + + K L+ +++E
Sbjct: 985 AVLQKTELENKLQQQLTQAA---QELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESE 1041
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHK 574
L +Q +V KL QE L ++ N +L + + + + E+Q +
Sbjct: 1042 LLA--TRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQ 1099
Query: 575 LEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L++ Q+E+ L +L KL +E +++C R+ + +L+ L++H
Sbjct: 1100 ERCKALQDIQKEK-SLKEKELVNEKSKLAEIE-EIKC---RQEKEITKLNEELKSH 1150
Score = 46.4 bits (105), Expect = 3e-04
Identities = 55/314 (17%), Positives = 138/314 (43%), Gaps = 12/314 (3%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
++ L++ +++ +D + EK+ E + + ++ S SEL K
Sbjct: 223 VAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQE 282
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE--NYDTVMRLNKQLT 416
Y + ++L++ L ++ T +N L K+++ L+E N ++V + N Q T
Sbjct: 283 VAVYVQELQKLKSSVNELTQKNQTLTEN----LLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K+L+ ++ + ++++++ ++ + + T L +E +++K ++
Sbjct: 339 LHQKDLD--CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFK 396
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++QQ EK+ ++ + + L +++ + L LK Q+QL L ++
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLK--EQRQLSSEKLMDKEQQ 454
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLA 596
L +E + K N + Q+ + ++QH+ E L++ +++ + L
Sbjct: 455 VADLQLKLSRLEEQLKEKVTNSTE-LQHQLDKTKQQHQ-EQQALQQSTTAKLREAQNDLE 512
Query: 597 QAAEKLGLLESKVE 610
Q ++G + K++
Sbjct: 513 QVLRQIGDKDQKIQ 526
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/148 (22%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Query: 368 QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALE 427
+LQ + SL+ + E N ++ KE + LK+ + + +L +K E ++
Sbjct: 1174 ELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEF---IEKEAKLHSEIKEKEVGMK 1230
Query: 428 KEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
K + IT LN+ + +V E + L+ + ++ R AV+E + Q+
Sbjct: 1231 KHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQD 1290
Query: 488 QCSEVLKKCDFLDNEVKTLR-QHLELQK 514
+ +L++C + E++ L+ + LELQ+
Sbjct: 1291 ERRALLERCLKGEGEIEKLQTKVLELQR 1318
Score = 43.2 bits (97), Expect = 0.003
Identities = 76/334 (22%), Positives = 142/334 (42%), Gaps = 38/334 (11%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
M ++R +++ KL++ +L + +E + ++ + V + QK S
Sbjct: 240 MTLERERES--EKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSV 297
Query: 349 ESELYKTLDLAHDYQDKCKQLQN-EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
K L + K + E+K EE ++ + N+ L KD + L+
Sbjct: 298 NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKK--NIQATLHQKDLDCQQLQS---- 351
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD----- 462
RL+ T + E EK + A K ++E+ + Q + E L Q+R+
Sbjct: 352 --RLSASETSLHRIHVELSEKGE-ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQH 408
Query: 463 --LLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKCDFLDNEVKTLRQHLELQKNELK 518
L+S++N+ S+ E+QL E + E L +D E + L+L + E
Sbjct: 409 GLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLE-- 466
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
+QL++ V E Q QLD+ +++ + L+++ LR E Q+ LE
Sbjct: 467 ----EQLKEKV-TNSTELQHQLDKTKQQHQEQQALQQSTTAK------LR-EAQNDLE-Q 513
Query: 579 VLEEKQREEIKLYRLQ--LAQAAEKLGLLESKVE 610
VL + ++ K+ L+ L ++ E + LLE + E
Sbjct: 514 VLRQIGDKDQKIQNLEALLQKSKENISLLEKERE 547
Score = 41.1 bits (92), Expect = 0.012
Identities = 78/312 (25%), Positives = 140/312 (44%), Gaps = 44/312 (14%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL E +L + R +++ + + EK++ + + VAD Q K S E +L + + +
Sbjct: 421 SKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQ---VAD-LQLKLSRLEEQLKEKVTNS 476
Query: 360 HDYQ---DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+ Q DK KQ E+++L++ +L + D E VL++ D +
Sbjct: 477 TELQHQLDKTKQQHQEQQALQQSTTAKLRE-----AQNDLE-QVLRQIGDKDQK------ 524
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
++NLE L+K K + +L +IQ+ ET +L Q ++ K+ +E+
Sbjct: 525 --IQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE--KNHTLQEQ---- 576
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
QL EK SE K+ + L ++ QK L+ + L ++ + E
Sbjct: 577 --VTQLTEKLKNQSESHKQAQ------ENLHDQVQEQKAHLRAAQDRVL--SLETSVNEL 626
Query: 537 QEQLDRA-EREMENDARLK---ENNIVDSFNKQILRIEEQHKLEI--NVLEEKQREEIKL 590
QL+ + E+ + D ++K E + K R + Q+ L+ N L++KQ+E K+
Sbjct: 627 NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKI 686
Query: 591 YRLQLAQAAEKL 602
QL Q KL
Sbjct: 687 -TTQLDQVTAKL 697
Score = 39.1 bits (87), Expect = 0.049
Identities = 51/250 (20%), Positives = 107/250 (42%), Gaps = 28/250 (11%)
Query: 326 KMICEVENFRVVAD-DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE------ 378
K+I E++ + + D+ KK + D+ + K K+L NEK L E
Sbjct: 1075 KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 379 QLNTELDNVNVMLSNKD----KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK---- 430
+ E+ +N L + KEI LK+ +++ +L +L+ A+E+EK
Sbjct: 1135 RQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQ 1194
Query: 431 FAHDSTKSNITELNKRI--QSVNDETLLLTQERDLLKSKVNEER---------SRCAVIE 479
D K EL K + + + +E + K + NE + ++
Sbjct: 1195 ILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVK 1254
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
++ Q + SE+ K+ D L E+ L ++ ++E + ++ L+ ++++ Q +
Sbjct: 1255 KEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGE--GEIEKLQTK 1312
Query: 540 LDRAEREMEN 549
+ +R+++N
Sbjct: 1313 VLELQRKLDN 1322
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/306 (20%), Positives = 127/306 (41%), Gaps = 14/306 (4%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+RAED E + + + +K E L K H ++K K L E
Sbjct: 70 ERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 128
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK---QLTDCVKNLEEALEKEK 430
L+E + + + +D L+ D V LNK +L V++LE +LE+EK
Sbjct: 129 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 188
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ N +L ++ + L L ++ L ++ ++ ++ ++ ++Q
Sbjct: 189 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 248
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ KK L ++ L + +E ++ + +KQ D +L+E E+L+ A
Sbjct: 249 QFQKKIKELQARIEELEEEIEAER-ATRAKTEKQRSD-YARELEELSERLEEAGGVTSTQ 306
Query: 551 ARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
L + + F K +EE QH+ + L +K + + +L + + L ++
Sbjct: 307 IELNKKREAE-FLKLRRDLEEATLQHEAMVATLRKKHADSV----AELGEQIDNLQRVKQ 361
Query: 608 KVECQR 613
K+E ++
Sbjct: 362 KLEKEK 367
Score = 54.0 bits (124), Expect = 2e-06
Identities = 63/311 (20%), Positives = 133/311 (42%), Gaps = 35/311 (11%)
Query: 311 NSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKC 366
NSL A D+ ++ +K++ E E + + + K++ +EL+K + + D+
Sbjct: 582 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 641
Query: 367 KQLQNEKKSLEEQL----------------------NTELDNVNVMLSNKDKEIDVLKEN 404
+ ++ E K+LE+++ EL+ ++ L+ ++ E L+
Sbjct: 642 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA-ALEHE 700
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL 464
++R+ +LT ++ + ++ + K N + +QS D + E L
Sbjct: 701 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRL 760
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQK 523
K K+ + + IE QL Q +E LK + ++K + HL + + + Q
Sbjct: 761 KKKMEGDLNE---IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQL 817
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ + LQ E+L + E +L E ++DS N+ R++ H +++ K
Sbjct: 818 AIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NE---RVQLLHTQNTSLIHTK 873
Query: 584 QREEIKLYRLQ 594
++ E L +LQ
Sbjct: 874 KKLETDLMQLQ 884
Score = 52.0 bits (119), Expect = 6e-06
Identities = 54/278 (19%), Positives = 130/278 (46%), Gaps = 12/278 (4%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ EL K+ + ++K L EK L+ Q+ E +N +L +++ ++K +
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESEN---LLDAEERCDQLIKAKFQLE 62
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ K++T+ ++ EE + + +EL K I + + +E+ ++KV
Sbjct: 63 AKI-KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 121
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED- 527
+ +++ + + + + + ++++ + N+ K ++Q+ED
Sbjct: 122 KNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVN-SLNKTKSKLEQQVEDL 180
Query: 528 -AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEEQHK-LEINVLEEKQ 584
+ L + ++ + L+R +R++E D +L + +I+D N KQ L + K E L+ K
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKV 240
Query: 585 REEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGET 619
+E L ++ ++ + ++ LE ++E +R R +T
Sbjct: 241 EDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 278
Score = 39.1 bits (87), Expect = 0.049
Identities = 52/289 (17%), Positives = 124/289 (42%), Gaps = 11/289 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
+KK + +EL + +D + K ++ ++E K + L++ +++V+ +N +K L
Sbjct: 339 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 398
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ N+++ + L + + + E + ++ TQ+
Sbjct: 399 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 458
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ LK ++ EE + L ++ C ++L++ + E K Q + N +
Sbjct: 459 EELKRQLEEENKAKNALGHALQSSRHDC-DLLREQYEEEQEGKAELQRALSKANSEVAQW 517
Query: 522 QKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNI-VDSFNKQILRIEEQHKLEINV 579
+ + E + + +E +E + A+R +++ +++ N S K R+ Q ++E ++
Sbjct: 518 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL--QGEVE-DL 574
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ + +R L Q L E K +C+ E+ A L A+L+
Sbjct: 575 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCE-----ESQAELEASLK 618
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/306 (20%), Positives = 127/306 (41%), Gaps = 14/306 (4%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+RAED E + + + +K E L K H ++K K L E
Sbjct: 70 ERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 128
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK---QLTDCVKNLEEALEKEK 430
L+E + + + +D L+ D V LNK +L V++LE +LE+EK
Sbjct: 129 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 188
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ N +L ++ + L L ++ L ++ ++ ++ ++ ++Q
Sbjct: 189 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 248
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ KK L ++ L + +E ++ + +KQ D +L+E E+L+ A
Sbjct: 249 QFQKKIKELQARIEELEEEIEAER-ATRAKTEKQRSD-YARELEELSERLEEAGGVTSTQ 306
Query: 551 ARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
L + + F K +EE QH+ + L +K + + +L + + L ++
Sbjct: 307 IELNKKREAE-FLKLRRDLEEATLQHEAMVATLRKKHADSV----AELGEQIDNLQRVKQ 361
Query: 608 KVECQR 613
K+E ++
Sbjct: 362 KLEKEK 367
Score = 53.6 bits (123), Expect = 2e-06
Identities = 63/311 (20%), Positives = 133/311 (42%), Gaps = 35/311 (11%)
Query: 311 NSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKC 366
NSL A D+ ++ +K++ E E + + + K++ +EL+K + + D+
Sbjct: 582 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 641
Query: 367 KQLQNEKKSLEEQL----------------------NTELDNVNVMLSNKDKEIDVLKEN 404
+ ++ E K+LE+++ EL+ ++ L+ ++ E L+
Sbjct: 642 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA-ALEHE 700
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL 464
++R+ +LT ++ + ++ + K N + +QS D + E L
Sbjct: 701 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 760
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQK 523
K K+ + + IE QL Q +E LK + ++K + HL + + + Q
Sbjct: 761 KKKMEGDLNE---IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQL 817
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ + LQ E+L + E +L E ++DS N+ R++ H +++ K
Sbjct: 818 AIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NE---RVQLLHTQNTSLIHTK 873
Query: 584 QREEIKLYRLQ 594
++ E L +LQ
Sbjct: 874 KKLETDLMQLQ 884
Score = 52.0 bits (119), Expect = 6e-06
Identities = 54/278 (19%), Positives = 130/278 (46%), Gaps = 12/278 (4%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ EL K+ + ++K L EK L+ Q+ E +N +L +++ ++K +
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESEN---LLDAEERCDQLIKAKFQLE 62
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ K++T+ ++ EE + + +EL K I + + +E+ ++KV
Sbjct: 63 AKI-KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 121
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED- 527
+ +++ + + + + + ++++ + N+ K ++Q+ED
Sbjct: 122 KNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVN-SLNKTKSKLEQQVEDL 180
Query: 528 -AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEEQHK-LEINVLEEKQ 584
+ L + ++ + L+R +R++E D +L + +I+D N KQ L + K E L+ K
Sbjct: 181 ESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKV 240
Query: 585 REEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGET 619
+E L ++ ++ + ++ LE ++E +R R +T
Sbjct: 241 EDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 278
Score = 39.5 bits (88), Expect = 0.037
Identities = 52/289 (17%), Positives = 124/289 (42%), Gaps = 11/289 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
+KK + +EL + +D + K ++ ++E K + L++ +++V+ +N +K L
Sbjct: 339 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 398
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ N+++ + L + + + E + ++ TQ+
Sbjct: 399 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 458
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ LK ++ EE + L ++ C ++L++ + E K Q + N +
Sbjct: 459 EELKRQLEEENKAKNALAHALQSSRHDC-DLLREQYEEEQEGKAELQRALSKANSEVAQW 517
Query: 522 QKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNI-VDSFNKQILRIEEQHKLEINV 579
+ + E + + +E +E + A+R +++ +++ N S K R+ Q ++E ++
Sbjct: 518 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL--QGEVE-DL 574
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ + +R L Q L E K +C+ E+ A L A+L+
Sbjct: 575 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCE-----ESQAELEASLK 618
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/306 (20%), Positives = 127/306 (41%), Gaps = 14/306 (4%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+RAED E + + + +K E L K H ++K K L E
Sbjct: 925 ERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 983
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK---QLTDCVKNLEEALEKEK 430
L+E + + + +D L+ D V LNK +L V++LE +LE+EK
Sbjct: 984 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 1043
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ N +L ++ + L L ++ L ++ ++ ++ ++ ++Q
Sbjct: 1044 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 1103
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ KK L ++ L + +E ++ + +KQ D +L+E E+L+ A
Sbjct: 1104 QFQKKIKELQARIEELEEEIEAER-ATRAKTEKQRSD-YARELEELSERLEEAGGVTSTQ 1161
Query: 551 ARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
L + + F K +EE QH+ + L +K + + +L + + L ++
Sbjct: 1162 IELNKKREAE-FLKLRRDLEEATLQHEAMVATLRKKHADSV----AELGEQIDNLQRVKQ 1216
Query: 608 KVECQR 613
K+E ++
Sbjct: 1217 KLEKEK 1222
Score = 53.6 bits (123), Expect = 2e-06
Identities = 62/296 (20%), Positives = 137/296 (46%), Gaps = 24/296 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEIDV 400
K++ E E+ + +D+ + + ++K LEE+L T E +++ + + + + +
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL +K + E E E + + +T ++++ E +
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDE----EEINAELTAKKRKLEDECSELKKDIDD 957
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQK---- 514
+L +KV +E+ + L E+ + E + K ++ Q +LQ
Sbjct: 958 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 1017
Query: 515 ----NELKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
N+ K ++Q+ED + L + ++ + L+R +R++E D +L + +I+D N KQ L
Sbjct: 1018 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 1077
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGET 619
+ K E L+ K +E L ++ ++ + ++ LE ++E +R R +T
Sbjct: 1078 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 1133
Score = 53.6 bits (123), Expect = 2e-06
Identities = 63/311 (20%), Positives = 133/311 (42%), Gaps = 35/311 (11%)
Query: 311 NSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKC 366
NSL A D+ ++ +K++ E E + + + K++ +EL+K + + D+
Sbjct: 1437 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 1496
Query: 367 KQLQNEKKSLEEQL----------------------NTELDNVNVMLSNKDKEIDVLKEN 404
+ ++ E K+LE+++ EL+ ++ L+ ++ E L+
Sbjct: 1497 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA-ALEHE 1555
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL 464
++R+ +LT ++ + ++ + K N + +QS D + E L
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQK 523
K K+ + + IE QL Q +E LK + ++K + HL + + + Q
Sbjct: 1616 KKKMEGDLNE---IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQL 1672
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ + LQ E+L + E +L E ++DS N+ R++ H +++ K
Sbjct: 1673 AIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NE---RVQLLHTQNTSLIHTK 1728
Query: 584 QREEIKLYRLQ 594
++ E L +LQ
Sbjct: 1729 KKLETDLMQLQ 1739
Score = 40.7 bits (91), Expect = 0.016
Identities = 52/289 (17%), Positives = 125/289 (43%), Gaps = 11/289 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
+KK + +EL + +D + K ++ ++E K + L++ +++V+ +N +K L
Sbjct: 1194 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 1253
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ N+++ + L + + + E + ++ TQ+
Sbjct: 1254 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 1313
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ LK ++ EE + L ++ C ++L++ + E K Q + N +
Sbjct: 1314 EELKRQLEEENKAKNALAHALQSSRHDC-DLLREQYEEEQEGKAELQRALSKANSEVAQW 1372
Query: 522 QKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNI-VDSFNKQILRIEEQHKLEINV 579
+ + E + + +E +E ++ A+R +++ +++ N S K R+ Q ++E ++
Sbjct: 1373 RTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRL--QGEVE-DL 1429
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ + +R L Q L E K +C+ E+ A L A+L+
Sbjct: 1430 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCE-----ESQAELEASLK 1473
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 59.3 bits (137), Expect = 4e-08
Identities = 63/306 (20%), Positives = 127/306 (41%), Gaps = 14/306 (4%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+RAED E + + + +K E L K H ++K K L E
Sbjct: 152 ERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEL 210
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK---QLTDCVKNLEEALEKEK 430
L+E + + + +D L+ D V LNK +L V++LE +LE+EK
Sbjct: 211 SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEK 270
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ N +L ++ + L L ++ L ++ ++ ++ ++ ++Q
Sbjct: 271 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 330
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ KK L ++ L + +E ++ + +KQ D +L+E E+L+ A
Sbjct: 331 QFQKKIKELQARIEELEEEIEAER-ATRAKTEKQRSD-YARELEELSERLEEAGGVTSTQ 388
Query: 551 ARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
L + + F K +EE QH+ + L +K + + +L + + L ++
Sbjct: 389 IELNKKREAE-FLKLRRDLEEATLQHEAMVATLRKKHADSV----AELGEQIDNLQRVKQ 443
Query: 608 KVECQR 613
K+E ++
Sbjct: 444 KLEKEK 449
Score = 54.4 bits (125), Expect = 1e-06
Identities = 66/312 (21%), Positives = 134/312 (42%), Gaps = 37/312 (11%)
Query: 311 NSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKC 366
NSL A D+ ++ +K++ E E + + + K++ +EL+K + + D+
Sbjct: 664 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 723
Query: 367 KQLQNEKKSLEEQL----------------------NTELDNVNVMLSNKDKEIDVLKEN 404
+ ++ E K+LE+++ EL+ ++ L+ ++ E L+
Sbjct: 724 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA-ALEHE 782
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL 464
++R+ +LT ++ + ++ + K N + +QS D + E L
Sbjct: 783 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 842
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE--LQKNELKCHYQ 522
K K+ + + IE QL Q +E LK + ++K + HL+ LQ E Q
Sbjct: 843 KKKMEGDLNE---IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQE-DLKEQ 898
Query: 523 KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEE 582
+ + LQ E+L + E +L E ++DS N+ R++ H +++
Sbjct: 899 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NE---RVQLLHTQNTSLIHT 954
Query: 583 KQREEIKLYRLQ 594
K++ E L +LQ
Sbjct: 955 KKKLETDLMQLQ 966
Score = 53.6 bits (123), Expect = 2e-06
Identities = 62/296 (20%), Positives = 137/296 (46%), Gaps = 24/296 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEIDV 400
K++ E E+ + +D+ + + ++K LEE+L T E +++ + + + + +
Sbjct: 69 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 128
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL +K + E E E + + +T ++++ E +
Sbjct: 129 AEERCDQLIKAKFQLEAKIKEVTERAEDE----EEINAELTAKKRKLEDECSELKKDIDD 184
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQK---- 514
+L +KV +E+ + L E+ + E + K ++ Q +LQ
Sbjct: 185 LELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDK 244
Query: 515 ----NELKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
N+ K ++Q+ED + L + ++ + L+R +R++E D +L + +I+D N KQ L
Sbjct: 245 VNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQL 304
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGET 619
+ K E L+ K +E L ++ ++ + ++ LE ++E +R R +T
Sbjct: 305 DERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 360
Score = 40.7 bits (91), Expect = 0.016
Identities = 52/289 (17%), Positives = 125/289 (43%), Gaps = 11/289 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
+KK + +EL + +D + K ++ ++E K + L++ +++V+ +N +K L
Sbjct: 421 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 480
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ N+++ + L + + + E + ++ TQ+
Sbjct: 481 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 540
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ LK ++ EE + L ++ C ++L++ + E K Q + N +
Sbjct: 541 EELKRQLEEENKAKNALAHALQSSRHDC-DLLREQYEEEQEGKAELQRALSKANSEVAQW 599
Query: 522 QKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNI-VDSFNKQILRIEEQHKLEINV 579
+ + E + + +E +E ++ A+R +++ +++ N S K R+ Q ++E ++
Sbjct: 600 RTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRL--QGEVE-DL 656
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ + +R L Q L E K +C+ E+ A L A+L+
Sbjct: 657 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCE-----ESQAELEASLK 700
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 59.3 bits (137), Expect = 4e-08
Identities = 54/292 (18%), Positives = 128/292 (43%), Gaps = 15/292 (5%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+ ++K R+ +R T D+A ++ +K+ E+ +A+ E K
Sbjct: 332 KEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ---K 388
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
+ ++Q++ + Q ++L+++ + L +VL+ D + + +Q
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ 448
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
L + ++ ++ L + + A +++ EL + ++ + E LL + +V +
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
I+Q L + QN E+ K + ++ L++ + Q+N L L KL+
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSL-----------TLEKLK 557
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
L++ +R+ D K + ++ N ++ + E++ K ++ LE K++E
Sbjct: 558 LAVADLEK-QRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKE 608
Score = 56.4 bits (130), Expect = 3e-07
Identities = 66/290 (22%), Positives = 132/290 (45%), Gaps = 29/290 (10%)
Query: 308 RLTNSLDRAEDRH---RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
+L LD A++ + + ++ +I EVE+ + + ++ S ++++ L
Sbjct: 2580 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV----S 2635
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K Q++ E + +EQ N EL N+ V L K I VL+ ++ + L KNLE
Sbjct: 2636 KLSQVEGEHQLWKEQ-NLELRNLTVELEQK---IQVLQSKNASLQDTLEVLQSSYKNLEN 2691
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LE K S + ++ + + E + Q+ L+ +++ E++R A Q L E
Sbjct: 2692 ELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 2751
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLDR 542
+ + LK+ ++E+K L C ++ Q+ E V ++ E+Q +L
Sbjct: 2752 EIKSSKDQLKELTLENSELK----------KSLDCMHKDQVEKEGKVREEIAEYQLRLHE 2801
Query: 543 AEREMEN---DARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQRE 586
AE++ + D + + ++ +++ EE KLEI++L+ + E
Sbjct: 2802 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 2851
Score = 53.2 bits (122), Expect = 3e-06
Identities = 67/286 (23%), Positives = 134/286 (46%), Gaps = 22/286 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q+ TS ++ + +TL A + ++K QL N+K E+ EL N +L + KE+ +L
Sbjct: 889 QEDTSAHQNVVAETLS-ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL 947
Query: 402 -------KENYDTVMRLNK----QLTD---CVKNLEEALEKEKF-AHDSTKSNITELNKR 446
K+ +++ LNK +LT +K + +L +EK ++S +++R
Sbjct: 948 SETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDER 1007
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+S+++ + QE+ +L + E + + L +K E K + L NE +L
Sbjct: 1008 EKSISELSDQYKQEKLILLQRCEETGN----AYEDLSQKYKAAQEKNSKLECLLNECTSL 1063
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
++ + + +LK + K+ ++ L KL +E+ E+E + + + D+ N
Sbjct: 1064 CENRKNELEQLKEAFAKEHQE-FLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
K EI L+E+Q + K L + + + ++++K ECQ
Sbjct: 1123 SEAGGL-KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQ 1167
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 13/247 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDK-CKQLQNE-KKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+K S LY DL +K C + NE K+ + L EL V + E+D
Sbjct: 2006 EKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDT 2065
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ + + +L++++ + + LE + ++ + E + +Q+++ + L ++
Sbjct: 2066 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2125
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
+ L+ K+ + CE +NQ +++ K+ + L E ++L+ L E K +
Sbjct: 2126 KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLN 2184
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
K LE A++ K EF +L + E+ R K +RIE K ++++
Sbjct: 2185 VSKALEAALVEK-GEFALRLSSTQEEVHQLRR--------GIEKLRVRIEADEKKQLHIA 2235
Query: 581 EE-KQRE 586
E+ K+RE
Sbjct: 2236 EKLKERE 2242
Score = 50.4 bits (115), Expect = 2e-05
Identities = 74/307 (24%), Positives = 133/307 (43%), Gaps = 33/307 (10%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ V +A +AA+ + E LRL+++ + R+ +EK+ R+ AD+ KK H
Sbjct: 2183 LNVSKALEAALVEKGEFALRLSSTQEEVHQL-RRGIEKL-----RVRIEADE--KKQLHI 2234
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + +DK + L+ E + EE N EL V + N E++ LK + +
Sbjct: 2235 AEKLKERERENDSLKDKVENLERELQMSEE--NQEL--VILDAENSKAEVETLKTQIEEM 2290
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R K + L E + ++EL+K + S L +E++ + ++
Sbjct: 2291 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS----LLEEKEQAEIQI 2346
Query: 469 NEERSRCAVIEQQLCEKQNQC-------SEVLKKCD-FLD---NEVKTLRQHLELQKNEL 517
EE + Q ++ N+ E++K + LD E LR +E + L
Sbjct: 2347 KEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARL 2406
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKLE 576
+ +KQL VL +L+E + D + +EN R E + N++ +E E K E
Sbjct: 2407 EADEKKQL--CVLQQLKESEHHADLLKGRVENLERELE---IARTNQEHAALEAENSKGE 2461
Query: 577 INVLEEK 583
+ L+ K
Sbjct: 2462 VETLKAK 2468
Score = 45.6 bits (103), Expect = 6e-04
Identities = 72/330 (21%), Positives = 143/330 (43%), Gaps = 24/330 (7%)
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA-HDYQDKCK 367
LTN L + ++R + LE + EN + + + S + L + ++
Sbjct: 2493 LTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVA 2551
Query: 368 QLQNEK---KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
L N++ K+ E+ L+++++ + + + + +D K NY + L V++ ++
Sbjct: 2552 ALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQ 2611
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LEK+ K+ I + + + ++ + E L K + E R+ +EQ++
Sbjct: 2612 KLEKKDEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQV 2667
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE 544
Q++ + + + L + K L LEL K + +K + K+ + +L R
Sbjct: 2668 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK------VNKMTAKETELQREM 2721
Query: 545 REM-ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
EM + A L+E S K L E Q LE + Q +E+ L +L ++ + +
Sbjct: 2722 HEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH 2778
Query: 604 LLESKVECQRRRRGETA---ARLHAALQAH 630
+ +VE + + R E A RLH A + H
Sbjct: 2779 --KDQVEKEGKVREEIAEYQLRLHEAEKKH 2806
Score = 42.7 bits (96), Expect = 0.004
Identities = 55/269 (20%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 327 MICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN 386
+I + E+F D+ +K S S+ YK L +C++ N + L ++ +
Sbjct: 993 LIQKSESFANYIDEREKSISEL-SDQYKQEKLI--LLQRCEETGNAYEDLSQKYKAAQEK 1049
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
N L E L EN + K+ K +E L K FA + ++ + EL
Sbjct: 1050 -NSKLECLLNECTSLCENRKNELEQLKEAF--AKEHQEFLTKLAFAEERNQNLMLELETV 1106
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
Q++ E +T ++ KS+ + ++++ + Q + +++L+ +NE
Sbjct: 1107 QQALRSE---MTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQ-----ENE---- 1154
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
Q +++ K + +C Q + + ++E + + ++ + + D +KE ++ DS+N Q+
Sbjct: 1155 -QLMKVMKTKHEC--QNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISL-DSYNAQL 1210
Query: 567 LRIEEQ-HKLEINVLEEKQREEIKLYRLQ 594
+++E E+ + E ++ +E + LQ
Sbjct: 1211 VQLEAMLRNKELKLQESEKEKECLQHELQ 1239
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/299 (21%), Positives = 131/299 (43%), Gaps = 50/299 (16%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL 384
EK++ ++E+ + ++ Q K +H E+ L +H+Y ++ + L+ ++ E L+ E+
Sbjct: 627 EKLLTQMESEK---ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR----ENLSVEI 679
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
N++ +L +K E++ K Y M L ++ + ++ +E + +L
Sbjct: 680 RNLHNVLDSKSVEVETQKLAY---MELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLE 736
Query: 445 KRIQSVNDETL---LLTQE--------RDLLKSK-----VNEERSRCAV-IEQQ------ 481
++Q +++E + Q+ RDLLKSK NE+ R + +QQ
Sbjct: 737 HKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHS 796
Query: 482 ----------LCEKQNQC----SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++++C + K L N V +L LE QK ++ QKQ E+
Sbjct: 797 FANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK-QMNSDLQKQCEE 855
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
V K E +E L +AE +M + + + + + ++ LE K++E
Sbjct: 856 LVQIK-GEIEENLMKAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912
Score = 39.5 bits (88), Expect = 0.037
Identities = 58/291 (19%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 325 EKMICEVENFRVVADDA--QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT 382
E+ C +E + + A Q + E L + D Q +C++L K +EE L
Sbjct: 810 ERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMK 869
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
++ + I L+E+ + + ++N E+ L+ ++ ++ I E
Sbjct: 870 AEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 929
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
L K + D L + L S +E S + ++ E+ Q + LK+ + N+
Sbjct: 930 LKKSNHLLEDSLKELQLLSETL-SLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQ 988
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ----LDRAER--------EMEND 550
K +L +QK+E +Y + E ++ +++++ L R E +
Sbjct: 989 EK---MNL-IQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1044
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
A ++N+ ++ + + E K E+ L+E +E + + +LA A E+
Sbjct: 1045 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Score = 37.9 bits (84), Expect = 0.11
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 13/179 (7%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D KQ + E ++ E+L ++ + LS++ EID+LK + + LN L + LE
Sbjct: 2812 DTNKQYEVEIQTYREKLTSKEE----CLSSQKLEIDLLKSSKE---ELNNSLKATTQILE 2864
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E L+K K + + + + N+R Q + ++ + K + +E S+ +
Sbjct: 2865 E-LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ---- 2919
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLD 541
EKQ + + K D L E+K L++ LE + E + K + KL++ +E L+
Sbjct: 2920 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2978
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 59.3 bits (137), Expect = 4e-08
Identities = 85/348 (24%), Positives = 151/348 (43%), Gaps = 29/348 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A +++V +K+ A+ L++ +L L+ K LE V + R+ D QKK+
Sbjct: 737 ADSLEVKASKEQALQDLQQQ-RQLNTDLELRATELSKQLEMEKEIVSSTRL---DLQKKS 792
Query: 346 SHFES---ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
ES +L K + + + L E K E+LN + L E + L
Sbjct: 793 EALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 403 ENYDTVMRLNKQLTDCVKNLEEALEKE----KFAHDSTKSNITELNKRIQSVNDETLLLT 458
TV +++D +KN + EKE K A + EL ++Q + T L
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENT--LK 910
Query: 459 QERDLLKSKVNEERSRCAV------IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL 512
++++L KS E+ + + +++QL + QN + K+ L + L+Q E
Sbjct: 911 EQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQ 970
Query: 513 QKNELKCHYQKQLEDAVLAKLQ---EFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+K +++ Q +L+ AVL K + + Q+QL +A +E+ A KE V N + +
Sbjct: 971 KKKQIEA-LQGELKIAVLQKTELENKLQQQLTQAAQEL---AAEKEKISVLQNNYE--KS 1024
Query: 570 EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E K ++ + E+ R L EKL L + + R + G
Sbjct: 1025 QETFK-QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIG 1071
Score = 49.6 bits (113), Expect = 3e-05
Identities = 73/315 (23%), Positives = 144/315 (45%), Gaps = 36/315 (11%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS-LEEQLNT 382
LE+ E N + + D ++K + +E+ + +D + ++ +K + L E+LN
Sbjct: 144 LEEAQTENFNIKQMKDLFEQKAAQLATEI-ADIKSKYDEERSLREAAEQKVTRLTEELNK 202
Query: 383 E---LDNVNVMLSNKD--KEIDVLKENYDTVMRLNKQLTDCVKNLEEAL--EKEKFA--H 433
E + ++ L + +++ VLK+ V L +T + E L E +KF +
Sbjct: 203 EATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQY 262
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVL 493
S+++ I++L + E + QE LKS VNE + + + L +K+ +++
Sbjct: 263 ASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLE 322
Query: 494 KKCDFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDA 551
+K NE +++++ L + +L C +QL+ ++L + L R E+
Sbjct: 323 EK----HNEESVSKKNIQATLHQKDLDC---QQLQ----SRLSASETSLHRIHVELS--- 368
Query: 552 RLKENNIVDSFNKQILRIEE--QH-KLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
++ +++ +E QH K E L++ QREE + + LQL ++ L SK
Sbjct: 369 --EKGEATQKLKEELSEVETKYQHLKAEFKQLQQ-QREEKEQHGLQL---QSEINQLHSK 422
Query: 609 VECQRRRRGETAARL 623
+ R+ GE RL
Sbjct: 423 LLETERQLGEAHGRL 437
Score = 49.2 bits (112), Expect = 5e-05
Identities = 56/314 (17%), Positives = 138/314 (43%), Gaps = 12/314 (3%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
++ L++ +++ +D + EK+ E + F ++ S SEL K
Sbjct: 223 VAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLRSELSKGPQE 282
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE--NYDTVMRLNKQLT 416
Y + ++L++ L ++ T +N L K+++ L+E N ++V + N Q T
Sbjct: 283 VRVYVQELQKLKSSVNELTQKNQTLTEN----LLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
K+L+ ++ + ++++++ ++ + + T L +E +++K ++
Sbjct: 339 LHQKDLD--CQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFK 396
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++QQ EK+ ++ + + L +++ + L LK Q+QL L ++
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLK--EQRQLSSEKLMDKEQQ 454
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLA 596
L +E + K N + Q+ + ++QH+ E L++ +++ + L
Sbjct: 455 VADLQLKLSRLEEQLKEKVTNSTE-LQHQLDKTKQQHQ-EQQALQQSTTAKLREAQNDLE 512
Query: 597 QAAEKLGLLESKVE 610
Q ++G + K++
Sbjct: 513 QVLRQIGEKDQKIQ 526
Score = 48.4 bits (110), Expect = 8e-05
Identities = 57/296 (19%), Positives = 130/296 (43%), Gaps = 12/296 (4%)
Query: 337 VADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK 396
V+D + S FE E K D + CK+L+++ + E E + L + +
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKE 924
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL 456
LK +++ Q + +K E+ ++ + + K + + K+I+++ E +
Sbjct: 925 ASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI 984
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++ L++K+ ++ ++ A Q+L ++ + S + + K L+ +++E
Sbjct: 985 AVLQKTELENKLQQQLTQAA---QELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESE 1041
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHK 574
L +Q +V KL QE L ++ N +L + + + + E+Q +
Sbjct: 1042 LLA--TRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQ 1099
Query: 575 LEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L++ Q+E+ L +L KL +E +++C R+ + +L+ L++H
Sbjct: 1100 ERCKALQDIQKEK-SLKEKELVNEKSKLAEIE-EIKC---RQEKEITKLNEELKSH 1150
Score = 43.6 bits (98), Expect = 0.002
Identities = 34/148 (22%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Query: 368 QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALE 427
+LQ + SL+ + E N ++ KE + LK+ + + +L +K E ++
Sbjct: 1174 ELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEF---IEKEAKLHSEIKEKEVGMK 1230
Query: 428 KEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
K + IT LN+ + +V E + L+ + ++ R AV+E + Q+
Sbjct: 1231 KHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQD 1290
Query: 488 QCSEVLKKCDFLDNEVKTLR-QHLELQK 514
+ +L++C + E++ L+ + LELQ+
Sbjct: 1291 ERRALLERCLKGEGEIEKLQTKVLELQR 1318
Score = 41.1 bits (92), Expect = 0.012
Identities = 52/256 (20%), Positives = 110/256 (42%), Gaps = 28/256 (10%)
Query: 326 KMICEVENFRVVAD-DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE------ 378
K+I E++ + + D+ KK + D+ + K K+L NEK L E
Sbjct: 1075 KLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKC 1134
Query: 379 QLNTELDNVNVMLSNKD----KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK---- 430
+ E+ +N L + KEI LK+ +++ +L +L+ A+E+EK
Sbjct: 1135 RQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQ 1194
Query: 431 FAHDSTKSNITELNKRI--QSVNDETLLLTQERDLLKSKVNEER---------SRCAVIE 479
D K EL K + + + +E + K + NE + ++
Sbjct: 1195 ILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVK 1254
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
++ Q + SE+ K+ D L E+ L ++ ++E + ++ L+ ++++ Q +
Sbjct: 1255 KEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGE--GEIEKLQTK 1312
Query: 540 LDRAEREMENDARLKE 555
+ +R+++N ++E
Sbjct: 1313 VLELQRKLDNTTAVQE 1328
Score = 37.5 bits (83), Expect = 0.15
Identities = 77/329 (23%), Positives = 140/329 (42%), Gaps = 41/329 (12%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL E +L + R +++ + + EK++ + + VAD Q K S E +L + + +
Sbjct: 421 SKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQ---VAD-LQLKLSRLEEQLKEKVTNS 476
Query: 360 HDYQ---DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+ Q DK KQ E+++L++ +L ++ + D+ + V+R +
Sbjct: 477 TELQHQLDKTKQQHQEQQALQQSTTAKL---------REAQNDL-----EQVLRQIGEKD 522
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
++NLE L+K K + +L +IQ+ ET +L Q ++ + +E
Sbjct: 523 QKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTE 582
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ------HLELQKNELKCHYQK------Q 524
++ Q E Q E L D + + LR LE NEL + Q
Sbjct: 583 NVKNQ-SESHKQAQENLH--DQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQ 639
Query: 525 LEDAVLAKLQEF--QEQLDRAER-EMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
L+ + AK + E A+R +++N +N + D ++++ +I Q L+
Sbjct: 640 LDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK-HQELNKITTQLDQVTAKLQ 698
Query: 582 EKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+KQ E L + EK LE K E
Sbjct: 699 DKQ-EHCSQLESHLKEYKEKYLSLEQKTE 726
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 59.3 bits (137), Expect = 4e-08
Identities = 57/265 (21%), Positives = 125/265 (47%), Gaps = 12/265 (4%)
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
+ ++K L EK L+ Q+ E DN+N D+ I + V +N++L D +
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEE 933
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E K++ D +EL K I + + +E+ ++KV A +++
Sbjct: 934 MNAELTAKKRKLEDEC----SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 989
Query: 481 QLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE 538
+ + K+ + + + D +V+ + + L K+++K Q + L + ++ +
Sbjct: 990 IIAKLTKEKKALQEAHQQALDDLQVEEDKVN-SLSKSKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 539 QLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ- 594
L+RA+R++E D +L + +I+D N ++ E+ K E ++ ++ + E++ +LQ
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQK 1108
Query: 595 -LAQAAEKLGLLESKVECQRRRRGE 618
L + ++ LE ++E +R R +
Sbjct: 1109 KLKENQARIEELEEELEAERTARAK 1133
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/299 (22%), Positives = 134/299 (44%), Gaps = 22/299 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1443 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1502
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK- 430
E K+L+E E+ ++ L K + L+ ++ KQL L+ ALE+ +
Sbjct: 1503 ENKNLQE----EISDLTEQLGEGGKNVHELE-------KVRKQLEVEKLELQSALEEAEA 1551
Query: 431 -FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
H+ K +L E L ++ ++ ++K N +R ++ L +
Sbjct: 1552 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV-VDSLQTSLDAETRSR 1610
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
+EVL+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R N
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AN 1666
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
D LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1667 D-DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1721
Score = 50.8 bits (116), Expect = 1e-05
Identities = 41/213 (19%), Positives = 104/213 (48%), Gaps = 7/213 (3%)
Query: 391 LSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
++ +E +KE + K+L + + +L + + + + N+ + +R +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 451 NDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL 510
+ L + + ++ +E A + + + +++CSE+ K D L+ + + +
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 511 ELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+N++K ++ D ++AKL + ++ L A ++ +D +++E+ V+S +K +++
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK-VNSLSKSKVKL 1029
Query: 570 EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
E+Q ++ LE +E K+ R+ L +A KL
Sbjct: 1030 EQQ----VDDLEGSLEQEKKV-RMDLERAKRKL 1057
Score = 43.6 bits (98), Expect = 0.002
Identities = 71/417 (17%), Positives = 173/417 (41%), Gaps = 38/417 (9%)
Query: 171 RVLEQYKASYSKNKPGATDSYSASSNQELKLPEMR-PFGENRESLKFIQNKYIDTIDSDL 229
++L ++K Y +++ S + + +L +++ + E+ E L+ + + + ++
Sbjct: 1453 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN-KNLQEEI 1511
Query: 230 LSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAM 289
L+E G+ + + K +LE E+L+ + A+ +
Sbjct: 1512 SDLTEQLGEGGKNVHELEKVRK----QLEVEKLELQ--SALEEAEASLEHEEGKILRAQL 1565
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+ ++ K KL E +++A+ H++ ++ + ++ ++ + E
Sbjct: 1566 EFNQIKAEIERKLAEK----DEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
Query: 350 SELYKT-LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + + L+H + + Q + KSL+ L + + L + + D LKEN V
Sbjct: 1622 GDLNEMEIQLSHANR-MAAEAQKQVKSLQSLLK----DTQIQLDDAVRANDDLKENIAIV 1676
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R N L ++ L +E+ + + + + E ++R+Q LL +Q L+ K
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ------LLHSQNTSLINQKK 1730
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+E L + Q++ E +++C + + K + ELK E
Sbjct: 1731 K--------MESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK------KEQD 1776
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
A L+ ++ +++ +++++ E + KQ+ ++E + + LE +Q+
Sbjct: 1777 TSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Score = 42.3 bits (95), Expect = 0.005
Identities = 56/282 (19%), Positives = 125/282 (44%), Gaps = 29/282 (10%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-------QLNT 382
++++ + +K+ E+++ + + +L EKK+L+E L
Sbjct: 955 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQV 1014
Query: 383 ELDNVNVMLSNK---DKEIDVLKENYD-------TVMRLNKQLTDCVKNLEEA---LEKE 429
E D VN + +K ++++D L+ + + + R ++L +K +E+ LE +
Sbjct: 1015 EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEND 1074
Query: 430 KF-AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
K + K ++N++ + DE +L Q L+ K+ E ++R +E++L ++
Sbjct: 1075 KLQLEEKLKKKEFDINQQNSKIEDEQVLALQ----LQKKLKENQARIEELEEELEAERTA 1130
Query: 489 CSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
++V K L E++ + + LE Q ++ A+ Q+ + L+ A + E
Sbjct: 1131 RAKVEKLRSDLSRELEEISERLEEAGGATS--VQIEMNKKREAEFQKMRRDLEEATLQHE 1188
Query: 549 NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
A DS + +I+ +++ + EK++ E KL
Sbjct: 1189 ATAAALRKKHADSVAELGEQIDNLQRVKQKL--EKEKSEFKL 1228
Score = 34.7 bits (76), Expect = 1.1
Identities = 70/332 (21%), Positives = 138/332 (41%), Gaps = 38/332 (11%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1124 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1180
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E TL ++ L+ + +L ++DN+ + +KE K D V
Sbjct: 1181 EEA---TLQ----HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+Q+ NLE+ + D +L + +S+ND T TQ ++K+
Sbjct: 1234 TSNMEQIIKAKANLEKV---SRTLEDQANEYRVKLEEAQRSLNDFT---TQ-----RAKL 1282
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
E A +QL EK+ S++ + +++ L++ LE + + ++A
Sbjct: 1283 QTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLE---------EEGKAKNA 1330
Query: 529 VLAKLQEFQEQLD--RAEREMENDARLKENNIVDSFNKQILRIEEQHKLE-INVLEEKQR 585
+ LQ + D R + E E +A+ + ++ N ++ + +++ + I EE +
Sbjct: 1331 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE 1390
Query: 586 EEIKL-YRLQLA-QAAEKLGLLESKVECQRRR 615
+ KL RLQ A +A E + S +E + R
Sbjct: 1391 AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR 1422
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 59.3 bits (137), Expect = 4e-08
Identities = 54/292 (18%), Positives = 128/292 (43%), Gaps = 15/292 (5%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+ ++K R+ +R T D+A ++ +K+ E+ +A+ E K
Sbjct: 332 KEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ---K 388
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
+ ++Q++ + Q ++L+++ + L +VL+ D + + +Q
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ 448
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
L + ++ ++ L + + A +++ EL + ++ + E LL + +V +
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
I+Q L + QN E+ K + ++ L++ + Q+N L L KL+
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSL-----------TLEKLK 557
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
L++ +R+ D K + ++ N ++ + E++ K ++ LE K++E
Sbjct: 558 LAVADLEK-QRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKE 608
Score = 56.4 bits (130), Expect = 3e-07
Identities = 66/290 (22%), Positives = 132/290 (45%), Gaps = 29/290 (10%)
Query: 308 RLTNSLDRAEDRH---RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
+L LD A++ + + ++ +I EVE+ + + ++ S ++++ L
Sbjct: 2484 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV----S 2539
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K Q++ E + +EQ N EL N+ V L K I VL+ ++ + L KNLE
Sbjct: 2540 KLSQVEGEHQLWKEQ-NLELRNLTVELEQK---IQVLQSKNASLQDTLEVLQSSYKNLEN 2595
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LE K S + ++ + + E + Q+ L+ +++ E++R A Q L E
Sbjct: 2596 ELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 2655
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLDR 542
+ + LK+ ++E+K L C ++ Q+ E V ++ E+Q +L
Sbjct: 2656 EIKSSKDQLKELTLENSELK----------KSLDCMHKDQVEKEGKVREEIAEYQLRLHE 2705
Query: 543 AEREMEN---DARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQRE 586
AE++ + D + + ++ +++ EE KLEI++L+ + E
Sbjct: 2706 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 2755
Score = 53.2 bits (122), Expect = 3e-06
Identities = 67/286 (23%), Positives = 134/286 (46%), Gaps = 22/286 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q+ TS ++ + +TL A + ++K QL N+K E+ EL N +L + KE+ +L
Sbjct: 889 QEDTSAHQNVVAETLS-ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL 947
Query: 402 -------KENYDTVMRLNK----QLTD---CVKNLEEALEKEKF-AHDSTKSNITELNKR 446
K+ +++ LNK +LT +K + +L +EK ++S +++R
Sbjct: 948 SETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDER 1007
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+S+++ + QE+ +L + E + + L +K E K + L NE +L
Sbjct: 1008 EKSISELSDQYKQEKLILLQRCEETGN----AYEDLSQKYKAAQEKNSKLECLLNECTSL 1063
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
++ + + +LK + K+ ++ L KL +E+ E+E + + + D+ N
Sbjct: 1064 CENRKNELEQLKEAFAKEHQE-FLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
K EI L+E+Q + K L + + + ++++K ECQ
Sbjct: 1123 SEAGGL-KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQ 1167
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 13/247 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDK-CKQLQNE-KKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+K S LY DL +K C + NE K+ + L EL V + E+D
Sbjct: 1910 EKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDT 1969
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ + + +L++++ + + LE + ++ + E + +Q+++ + L ++
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2029
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
+ L+ K+ + CE +NQ +++ K+ + L E ++L+ L E K +
Sbjct: 2030 KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLN 2088
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
K LE A++ K EF +L + E+ R K +RIE K ++++
Sbjct: 2089 VSKALEAALVEK-GEFALRLSSTQEEVHQLRR--------GIEKLRVRIEADEKKQLHIA 2139
Query: 581 EE-KQRE 586
E+ K+RE
Sbjct: 2140 EKLKERE 2146
Score = 50.4 bits (115), Expect = 2e-05
Identities = 74/307 (24%), Positives = 133/307 (43%), Gaps = 33/307 (10%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ V +A +AA+ + E LRL+++ + R+ +EK+ R+ AD+ KK H
Sbjct: 2087 LNVSKALEAALVEKGEFALRLSSTQEEVHQL-RRGIEKL-----RVRIEADE--KKQLHI 2138
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + +DK + L+ E + EE N EL V + N E++ LK + +
Sbjct: 2139 AEKLKERERENDSLKDKVENLERELQMSEE--NQEL--VILDAENSKAEVETLKTQIEEM 2194
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R K + L E + ++EL+K + S L +E++ + ++
Sbjct: 2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS----LLEEKEQAEIQI 2250
Query: 469 NEERSRCAVIEQQLCEKQNQC-------SEVLKKCD-FLD---NEVKTLRQHLELQKNEL 517
EE + Q ++ N+ E++K + LD E LR +E + L
Sbjct: 2251 KEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARL 2310
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKLE 576
+ +KQL VL +L+E + D + +EN R E + N++ +E E K E
Sbjct: 2311 EADEKKQL--CVLQQLKESEHHADLLKGRVENLERELE---IARTNQEHAALEAENSKGE 2365
Query: 577 INVLEEK 583
+ L+ K
Sbjct: 2366 VETLKAK 2372
Score = 46.4 bits (105), Expect = 3e-04
Identities = 74/346 (21%), Positives = 148/346 (42%), Gaps = 24/346 (6%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + + +R LTN L + ++R + LE + EN + + + S
Sbjct: 2381 RGLELDVVTIRSEKENLTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Query: 353 YKTLDLA-HDYQDKCKQLQNEK---KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L + ++ L N++ K+ E+ L+++++ + + + + +D K NY +
Sbjct: 2440 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L V++ ++ LEK+ K+ I + + + ++ + E L K +
Sbjct: 2500 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQN 2555
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
E R+ +EQ++ Q++ + + + L + K L LEL K + +K
Sbjct: 2556 LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK----- 2610
Query: 529 VLAKLQEFQEQLDRAEREM-ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
+ K+ + +L R EM + A L+E S K L E Q LE + Q +E
Sbjct: 2611 -VNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKE 2666
Query: 588 IKLYRLQLAQAAEKLGLLESKVECQRRRRGETA---ARLHAALQAH 630
+ L +L ++ + + + +VE + + R E A RLH A + H
Sbjct: 2667 LTLENSELKKSLDCMH--KDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Score = 42.7 bits (96), Expect = 0.004
Identities = 55/269 (20%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 327 MICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN 386
+I + E+F D+ +K S S+ YK L +C++ N + L ++ +
Sbjct: 993 LIQKSESFANYIDEREKSISEL-SDQYKQEKLI--LLQRCEETGNAYEDLSQKYKAAQEK 1049
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
N L E L EN + K+ K +E L K FA + ++ + EL
Sbjct: 1050 -NSKLECLLNECTSLCENRKNELEQLKEAF--AKEHQEFLTKLAFAEERNQNLMLELETV 1106
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
Q++ E +T ++ KS+ + ++++ + Q + +++L+ +NE
Sbjct: 1107 QQALRSE---MTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQ-----ENE---- 1154
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
Q +++ K + +C Q + + ++E + + ++ + + D +KE ++ DS+N Q+
Sbjct: 1155 -QLMKVMKTKHEC--QNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISL-DSYNAQL 1210
Query: 567 LRIEEQ-HKLEINVLEEKQREEIKLYRLQ 594
+++E E+ + E ++ +E + LQ
Sbjct: 1211 VQLEAMLRNKELKLQESEKEKECLQHELQ 1239
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/299 (21%), Positives = 131/299 (43%), Gaps = 50/299 (16%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL 384
EK++ ++E+ + ++ Q K +H E+ L +H+Y ++ + L+ ++ E L+ E+
Sbjct: 627 EKLLTQMESEK---ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR----ENLSVEI 679
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
N++ +L +K E++ K Y M L ++ + ++ +E + +L
Sbjct: 680 RNLHNVLDSKSVEVETQKLAY---MELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLE 736
Query: 445 KRIQSVNDETL---LLTQE--------RDLLKSK-----VNEERSRCAV-IEQQ------ 481
++Q +++E + Q+ RDLLKSK NE+ R + +QQ
Sbjct: 737 HKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHS 796
Query: 482 ----------LCEKQNQC----SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++++C + K L N V +L LE QK ++ QKQ E+
Sbjct: 797 FANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK-QMNSDLQKQCEE 855
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
V K E +E L +AE +M + + + + + ++ LE K++E
Sbjct: 856 LVQIK-GEIEENLMKAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912
Score = 39.5 bits (88), Expect = 0.037
Identities = 58/291 (19%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 325 EKMICEVENFRVVADDA--QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT 382
E+ C +E + + A Q + E L + D Q +C++L K +EE L
Sbjct: 810 ERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMK 869
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
++ + I L+E+ + + ++N E+ L+ ++ ++ I E
Sbjct: 870 AEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 929
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
L K + D L + L S +E S + ++ E+ Q + LK+ + N+
Sbjct: 930 LKKSNHLLEDSLKELQLLSETL-SLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQ 988
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ----LDRAER--------EMEND 550
K +L +QK+E +Y + E ++ +++++ L R E +
Sbjct: 989 EK---MNL-IQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1044
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
A ++N+ ++ + + E K E+ L+E +E + + +LA A E+
Sbjct: 1045 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Score = 37.9 bits (84), Expect = 0.11
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 13/179 (7%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D KQ + E ++ E+L ++ + LS++ EID+LK + + LN L + LE
Sbjct: 2716 DTNKQYEVEIQTYREKLTSKEE----CLSSQKLEIDLLKSSKE---ELNNSLKATTQILE 2768
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E L+K K + + + + N+R Q + ++ + K + +E S+ +
Sbjct: 2769 E-LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ---- 2823
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLD 541
EKQ + + K D L E+K L++ LE + E + K + KL++ +E L+
Sbjct: 2824 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2882
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 59.3 bits (137), Expect = 4e-08
Identities = 54/292 (18%), Positives = 128/292 (43%), Gaps = 15/292 (5%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+ ++K R+ +R T D+A ++ +K+ E+ +A+ E K
Sbjct: 332 KEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ---K 388
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
+ ++Q++ + Q ++L+++ + L +VL+ D + + +Q
Sbjct: 389 IKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ 448
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
L + ++ ++ L + + A +++ EL + ++ + E LL + +V +
Sbjct: 449 LENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAE 508
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
I+Q L + QN E+ K + ++ L++ + Q+N L L KL+
Sbjct: 509 LKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENSL-----------TLEKLK 557
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
L++ +R+ D K + ++ N ++ + E++ K ++ LE K++E
Sbjct: 558 LAVADLEK-QRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKE 608
Score = 56.4 bits (130), Expect = 3e-07
Identities = 66/290 (22%), Positives = 132/290 (45%), Gaps = 29/290 (10%)
Query: 308 RLTNSLDRAEDRH---RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
+L LD A++ + + ++ +I EVE+ + + ++ S ++++ L
Sbjct: 2484 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV----S 2539
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K Q++ E + +EQ N EL N+ V L K I VL+ ++ + L KNLE
Sbjct: 2540 KLSQVEGEHQLWKEQ-NLELRNLTVELEQK---IQVLQSKNASLQDTLEVLQSSYKNLEN 2595
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LE K S + ++ + + E + Q+ L+ +++ E++R A Q L E
Sbjct: 2596 ELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 2655
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLDR 542
+ + LK+ ++E+K L C ++ Q+ E V ++ E+Q +L
Sbjct: 2656 EIKSSKDQLKELTLENSELK----------KSLDCMHKDQVEKEGKVREEIAEYQLRLHE 2705
Query: 543 AEREMEN---DARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQRE 586
AE++ + D + + ++ +++ EE KLEI++L+ + E
Sbjct: 2706 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 2755
Score = 53.2 bits (122), Expect = 3e-06
Identities = 67/286 (23%), Positives = 134/286 (46%), Gaps = 22/286 (7%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
Q+ TS ++ + +TL A + ++K QL N+K E+ EL N +L + KE+ +L
Sbjct: 889 QEDTSAHQNVVAETLS-ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLL 947
Query: 402 -------KENYDTVMRLNK----QLTD---CVKNLEEALEKEKF-AHDSTKSNITELNKR 446
K+ +++ LNK +LT +K + +L +EK ++S +++R
Sbjct: 948 SETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDER 1007
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+S+++ + QE+ +L + E + + L +K E K + L NE +L
Sbjct: 1008 EKSISELSDQYKQEKLILLQRCEETGN----AYEDLSQKYKAAQEKNSKLECLLNECTSL 1063
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
++ + + +LK + K+ ++ L KL +E+ E+E + + + D+ N
Sbjct: 1064 CENRKNELEQLKEAFAKEHQE-FLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
K EI L+E+Q + K L + + + ++++K ECQ
Sbjct: 1123 SEAGGL-KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQ 1167
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/247 (22%), Positives = 110/247 (44%), Gaps = 13/247 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDK-CKQLQNE-KKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+K S LY DL +K C + NE K+ + L EL V + E+D
Sbjct: 1910 EKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDT 1969
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ + + +L++++ + + LE + ++ + E + +Q+++ + L ++
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2029
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
+ L+ K+ + CE +NQ +++ K+ + L E ++L+ L E K +
Sbjct: 2030 KTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLN 2088
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
K LE A++ K EF +L + E+ R K +RIE K ++++
Sbjct: 2089 VSKALEAALVEK-GEFALRLSSTQEEVHQLRR--------GIEKLRVRIEADEKKQLHIA 2139
Query: 581 EE-KQRE 586
E+ K+RE
Sbjct: 2140 EKLKERE 2146
Score = 50.4 bits (115), Expect = 2e-05
Identities = 74/307 (24%), Positives = 133/307 (43%), Gaps = 33/307 (10%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ V +A +AA+ + E LRL+++ + R+ +EK+ R+ AD+ KK H
Sbjct: 2087 LNVSKALEAALVEKGEFALRLSSTQEEVHQL-RRGIEKL-----RVRIEADE--KKQLHI 2138
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + +DK + L+ E + EE N EL V + N E++ LK + +
Sbjct: 2139 AEKLKERERENDSLKDKVENLERELQMSEE--NQEL--VILDAENSKAEVETLKTQIEEM 2194
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R K + L E + ++EL+K + S L +E++ + ++
Sbjct: 2195 ARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKS----LLEEKEQAEIQI 2250
Query: 469 NEERSRCAVIEQQLCEKQNQC-------SEVLKKCD-FLD---NEVKTLRQHLELQKNEL 517
EE + Q ++ N+ E++K + LD E LR +E + L
Sbjct: 2251 KEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARL 2310
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKLE 576
+ +KQL VL +L+E + D + +EN R E + N++ +E E K E
Sbjct: 2311 EADEKKQL--CVLQQLKESEHHADLLKGRVENLERELE---IARTNQEHAALEAENSKGE 2365
Query: 577 INVLEEK 583
+ L+ K
Sbjct: 2366 VETLKAK 2372
Score = 46.4 bits (105), Expect = 3e-04
Identities = 74/346 (21%), Positives = 148/346 (42%), Gaps = 24/346 (6%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R + + +R LTN L + ++R + LE + EN + + + S
Sbjct: 2381 RGLELDVVTIRSEKENLTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSSTA 2439
Query: 353 YKTLDLA-HDYQDKCKQLQNEK---KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ L + ++ L N++ K+ E+ L+++++ + + + + +D K NY +
Sbjct: 2440 MEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVL 2499
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L V++ ++ LEK+ K+ I + + + ++ + E L K +
Sbjct: 2500 QSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQN 2555
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
E R+ +EQ++ Q++ + + + L + K L LEL K + +K
Sbjct: 2556 LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK----- 2610
Query: 529 VLAKLQEFQEQLDRAEREM-ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
+ K+ + +L R EM + A L+E S K L E Q LE + Q +E
Sbjct: 2611 -VNKMTAKETELQREMHEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKE 2666
Query: 588 IKLYRLQLAQAAEKLGLLESKVECQRRRRGETA---ARLHAALQAH 630
+ L +L ++ + + + +VE + + R E A RLH A + H
Sbjct: 2667 LTLENSELKKSLDCMH--KDQVEKEGKVREEIAEYQLRLHEAEKKH 2710
Score = 42.7 bits (96), Expect = 0.004
Identities = 55/269 (20%), Positives = 122/269 (45%), Gaps = 23/269 (8%)
Query: 327 MICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN 386
+I + E+F D+ +K S S+ YK L +C++ N + L ++ +
Sbjct: 993 LIQKSESFANYIDEREKSISEL-SDQYKQEKLI--LLQRCEETGNAYEDLSQKYKAAQEK 1049
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
N L E L EN + K+ K +E L K FA + ++ + EL
Sbjct: 1050 -NSKLECLLNECTSLCENRKNELEQLKEAF--AKEHQEFLTKLAFAEERNQNLMLELETV 1106
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
Q++ E +T ++ KS+ + ++++ + Q + +++L+ +NE
Sbjct: 1107 QQALRSE---MTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQ-----ENE---- 1154
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
Q +++ K + +C Q + + ++E + + ++ + + D +KE ++ DS+N Q+
Sbjct: 1155 -QLMKVMKTKHEC--QNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISL-DSYNAQL 1210
Query: 567 LRIEEQ-HKLEINVLEEKQREEIKLYRLQ 594
+++E E+ + E ++ +E + LQ
Sbjct: 1211 VQLEAMLRNKELKLQESEKEKECLQHELQ 1239
Score = 41.9 bits (94), Expect = 0.007
Identities = 65/299 (21%), Positives = 131/299 (43%), Gaps = 50/299 (16%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL 384
EK++ ++E+ + ++ Q K +H E+ L +H+Y ++ + L+ ++ E L+ E+
Sbjct: 627 EKLLTQMESEK---ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR----ENLSVEI 679
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
N++ +L +K E++ K Y M L ++ + ++ +E + +L
Sbjct: 680 RNLHNVLDSKSVEVETQKLAY---MELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLE 736
Query: 445 KRIQSVNDETL---LLTQE--------RDLLKSK-----VNEERSRCAV-IEQQ------ 481
++Q +++E + Q+ RDLLKSK NE+ R + +QQ
Sbjct: 737 HKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHS 796
Query: 482 ----------LCEKQNQC----SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++++C + K L N V +L LE QK ++ QKQ E+
Sbjct: 797 FANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQK-QMNSDLQKQCEE 855
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
V K E +E L +AE +M + + + + + ++ LE K++E
Sbjct: 856 LVQIK-GEIEENLMKAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912
Score = 39.5 bits (88), Expect = 0.037
Identities = 58/291 (19%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 325 EKMICEVENFRVVADDA--QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT 382
E+ C +E + + A Q + E L + D Q +C++L K +EE L
Sbjct: 810 ERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMK 869
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
++ + I L+E+ + + ++N E+ L+ ++ ++ I E
Sbjct: 870 AEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE 929
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
L K + D L + L S +E S + ++ E+ Q + LK+ + N+
Sbjct: 930 LKKSNHLLEDSLKELQLLSETL-SLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQ 988
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ----LDRAER--------EMEND 550
K +L +QK+E +Y + E ++ +++++ L R E +
Sbjct: 989 EK---MNL-IQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYK 1044
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
A ++N+ ++ + + E K E+ L+E +E + + +LA A E+
Sbjct: 1045 AAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Score = 37.9 bits (84), Expect = 0.11
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 13/179 (7%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D KQ + E ++ E+L ++ + LS++ EID+LK + + LN L + LE
Sbjct: 2716 DTNKQYEVEIQTYREKLTSKEE----CLSSQKLEIDLLKSSKE---ELNNSLKATTQILE 2768
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E L+K K + + + + N+R Q + ++ + K + +E S+ +
Sbjct: 2769 E-LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ---- 2823
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLD 541
EKQ + + K D L E+K L++ LE + E + K + KL++ +E L+
Sbjct: 2824 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 2882
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 58.4 bits (135), Expect = 7e-08
Identities = 68/309 (22%), Positives = 143/309 (46%), Gaps = 47/309 (15%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
CE EN +++K E E+ + L + + ++ +NE + N E+ N
Sbjct: 1148 CEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSN-- 1205
Query: 389 VMLSNK-DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI 447
L NK + EI++ K T+ ++ Q D KNL L++ ++ N +L I
Sbjct: 1206 --LRNKYETEINITK---TTIKEISMQKEDDSKNLRNQLDR------LSREN-RDLKDEI 1253
Query: 448 QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
+ND L T++R R+ ++Q+ C SE+++K L+ E+K +
Sbjct: 1254 VRLNDSILQATEQR---------RRAEENALQQKACG-----SEIMQKKQHLEIELKQVM 1299
Query: 508 QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK---EN---NIVDS 561
Q Q++E +++ LE+A +Q+ ++++R + E + +A+ + EN + ++
Sbjct: 1300 Q----QRSEDNARHKQSLEEAA-KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNN 1354
Query: 562 FNKQILRIEEQHKLEINV-------LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++++I+ ++ Q + EIN+ L ++ E+ YR Q+ + L +++ +
Sbjct: 1355 YDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKN 1414
Query: 615 RRGETAARL 623
+T L
Sbjct: 1415 TLTQTTENL 1423
Score = 50.8 bits (116), Expect = 1e-05
Identities = 92/455 (20%), Positives = 185/455 (40%), Gaps = 30/455 (6%)
Query: 159 QPSSNKIYDRASRVLEQYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQ 218
+ + K + + L++ + K AT++ + QE +L +R E + ++
Sbjct: 1493 ETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVK 1552
Query: 219 NKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
++ I + SL EL K + NR + + + E E M
Sbjct: 1553 DQDITRFQN---SLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQA 1609
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFR--V 336
+ K + LR+ L L R + R ++ L ++ EVE R +
Sbjct: 1610 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHL-REKQRTQEELRRLSSEVEALRRQL 1668
Query: 337 VADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK 396
+ + K +H +E ++ +DK + L NE K E+L + +N+ ++
Sbjct: 1669 LQEQESVKQAHLRNEHFQKA-----IEDKSRSL-NESKIEIERLQSLTENLTKEHLMLEE 1722
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKN--LEEALEKEKFAHDST---KSNITELNKRIQSVN 451
E+ L+ YD + R + D KN + E + + +++ T + I +L + +++
Sbjct: 1723 ELRNLRLEYDDLRR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLR 1781
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
E ++ +++ E +++C + Q+ L K + + L++E+ +
Sbjct: 1782 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 1841
Query: 509 HLELQ---KNELKCHYQKQLEDAVLAKLQ--EFQEQLDRAEREMENDARLKEN--NIVDS 561
LE + K L+C Q+ D K Q +E + + E E E R K + + ++
Sbjct: 1842 TLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIER 1901
Query: 562 FNKQILRIEE--QHKLEINVLEEKQREEIKLYRLQ 594
+I RIEE + KLE + E + + E + R Q
Sbjct: 1902 LQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQ 1936
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/304 (18%), Positives = 127/304 (41%), Gaps = 25/304 (8%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA+++ E+E RV+ + + +E+EL K + + Y ++ L+N+ E ++N
Sbjct: 1162 KAIKEKEYEIERLRVLLQEEGTRKREYENELAK---VRNHYNEEMSNLRNK---YETEIN 1215
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
+ + K+ + L+ D + R N+ L D + L +++ + + N
Sbjct: 1216 ITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENAL 1275
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
+ ++ E + Q ++ +V ++RS E KQ+ E K +
Sbjct: 1276 QQ----KACGSEIMQKKQHLEIELKQVMQQRS-----EDNARHKQS-LEEAAKTIQDKNK 1325
Query: 502 EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS 561
E++ L+ + ++ + + Y+ +L + E++ + + E + + + I
Sbjct: 1326 EIERLKAEFQ-EEAKRRWEYENELSKV----RNNYDEEIISLKNQFETEINITKTTI-HQ 1379
Query: 562 FNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
Q ++ +I+ L + R EEIK + L Q E L +E ++ Q+ E
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439
Query: 619 TAAR 622
+ R
Sbjct: 1440 VSQR 1443
Score = 50.0 bits (114), Expect = 3e-05
Identities = 72/357 (20%), Positives = 158/357 (44%), Gaps = 51/357 (14%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K++ + L+E +++TN + E ++ ++ R V D ++ +
Sbjct: 1593 KLEEELEGMRRSLKEQAIKITNLTQQLEQASI-VKKRSEDDLRQQRDVLDGHLREKQRTQ 1651
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
EL + L+ + + +QL E++S++ Q + ++ + +K + ++ K + +
Sbjct: 1652 EELRR---LSSEVEALRRQLLQEQESVK-QAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTK-----------SNITELNKRIQSVNDETLLLT 458
L + LT LEE L + +D + + I EL ++Q N+ TL L
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 1767
Query: 459 -------QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
+ER+ L+ ++ + + + ++ E +NQC++V+++ + L ++K L Q
Sbjct: 1768 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQD-- 1825
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
A+LQ +++L+RA+ +E + R+K+ ++ +QI
Sbjct: 1826 ------------------KARLQRLEDELNRAKSTLEAETRVKQR--LECEKQQIQNDLN 1865
Query: 572 QHKLEINVLE------EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
Q K + + E E +RE+ + + L E+L ++E + RR+ E + R
Sbjct: 1866 QWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTR 1922
Score = 46.0 bits (104), Expect = 4e-04
Identities = 66/332 (19%), Positives = 146/332 (43%), Gaps = 19/332 (5%)
Query: 314 DRAEDRHRKALEKMICEV-ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+R+ K L+ + + EN R V +D Q++ + + L + + + Q++ E
Sbjct: 1402 NRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELR-QVTQMRTE 1460
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLEEALEKE 429
+ +Q LD+ + +K+KEI+ LK+ D K L D ++ ++ L+K
Sbjct: 1461 ESVRYKQ---SLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKA 1517
Query: 430 KFAHDST-------KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ T + +T L + V+ E + Q+ ++ + E + + +E++L
Sbjct: 1518 NSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 1577
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ SE K L+ E++ +R+ L+ Q ++ + +QLE A + K + ++ L R
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKI-TNLTQQLEQASIVK-KRSEDDL-R 1634
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+R++ + ++ + + +E + + E ++ ++ Q A +
Sbjct: 1635 QQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSR 1694
Query: 603 GLLESKVECQR-RRRGETAARLHAALQAHWRH 633
L ESK+E +R + E + H L+ R+
Sbjct: 1695 SLNESKIEIERLQSLTENLTKEHLMLEEELRN 1726
Score = 40.3 bits (90), Expect = 0.021
Identities = 67/315 (21%), Positives = 137/315 (43%), Gaps = 29/315 (9%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R+ L +A + + K+ + + + D ++ + + K D+ +Q+ K
Sbjct: 1509 RVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVS---QERTVKDQDITR-FQNSLK 1564
Query: 368 QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK-QLTDCVKNLEEAL 426
+LQ +K+ +EE+LN L S K K+++ E ++ ++T+ + LE+A
Sbjct: 1565 ELQLQKQKVEEELN-RLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQAS 1623
Query: 427 EKEKFAHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + D + L+ + Q +E L+ E + L+ ++ +E+ ++Q
Sbjct: 1624 IVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQES---VKQAHL 1680
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
++ + K L+ + + L +N K H + E L L+ + L R
Sbjct: 1681 RNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEE---LRNLRLEYDDLRRG 1737
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLE----INVLE---EKQREEIKLYRLQLA 596
E ++D +N + Q L+I LE IN L+ E R+EI+ ++ Q
Sbjct: 1738 RSEADSD----KNATILELRSQ-LQISNNRTLELQGLINDLQRERENLRQEIEKFQKQAL 1792
Query: 597 QAAEKLGLLESKVEC 611
+A+ + + ESK +C
Sbjct: 1793 EASNR--IQESKNQC 1805
Score = 39.9 bits (89), Expect = 0.028
Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 31/223 (13%)
Query: 368 QLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
+L+N K + LEE+L D N NK+K +D + Y Q + +LEE
Sbjct: 1028 KLKNTKIEVLEEELRLARD-ANSENCNKNKFLDQNLQKYQAEC---SQFKAKLASLEELK 1083
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ + S K N+ + +I+ +N++ LT E + +E+ R +E + +++
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYE-------IEDEKRRRKSVEDRFDQQK 1136
Query: 487 NQCSEVLK--KCDFLDNEVKTLRQHLELQKNEL-KCHYQKQLEDAVLAKLQEFQEQLDRA 543
N ++ K +C+ +++L QK E K +K+ E + +L+ ++
Sbjct: 1137 NDYDQLQKARQCE---------KENLGWQKLESEKAIKEKEYE---IERLRVLLQEEGTR 1184
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
+RE EN+ N+ +N+++ + +++ EIN+ + +E
Sbjct: 1185 KREYENELAKVRNH----YNEEMSNLRNKYETEINITKTTIKE 1223
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/261 (18%), Positives = 119/261 (45%), Gaps = 15/261 (5%)
Query: 292 DRAKDAAISKLR-EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
D+++ SK+ E LT +L + + L + E ++ R +A +
Sbjct: 1691 DKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATIL 1750
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
EL L ++++ + + L N+ + E L E++ I K V++
Sbjct: 1751 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQ 1810
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL---LTQERDLLKSK 467
+ L +K LE+ + + D ELN+ ++ ET + L E+ +++
Sbjct: 1811 ERESLLVKIKVLEQDKARLQRLED-------ELNRAKSTLEAETRVKQRLECEKQQIQND 1863
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+N+ +++ + E+ + + +++ + ++ + L +E++ L+ E+++ E +C +++LED
Sbjct: 1864 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQA--EIKRIEERC--RRKLED 1919
Query: 528 AVLAKLQEFQEQLDRAEREME 548
+ + + + R +RE++
Sbjct: 1920 STRETQSQLETERSRYQREID 1940
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 58.4 bits (135), Expect = 7e-08
Identities = 74/351 (21%), Positives = 148/351 (42%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 94 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 153
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 154 LMEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 212
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E Y + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 213 EEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 272
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 273 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 332
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 333 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 386
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 387 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 435
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/302 (23%), Positives = 133/302 (44%), Gaps = 31/302 (10%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMI-CEVENFRVVADDAQKKTSHF 348
DRA+ A K +A L L +L+ A ++ + L K E+E+ DD K
Sbjct: 752 DRAEAEAREKETKA-LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 810
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E + + + ++L++E ++ E+ +L E+ N+ M + ++++ E +
Sbjct: 811 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV-NLQAMKAQFERDLQGRDEQSE- 868
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
KQL V+ +E LE E+ +R +V L +DL
Sbjct: 869 --EKKKQLVRQVREMEAELEDER-------------KQRSMAVAARKKLEMDLKDLEAHI 913
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++R I+Q L + Q Q + +++ D D + ++NE K K +E
Sbjct: 914 DSANKNRDEAIKQ-LRKLQAQMKDCMRELD--DTRASREEILAQAKENEKKL---KSME- 966
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV--LEEKQR 585
A + +LQE +RA+R+ + + + I +S K L +EE+ +LE + LEE+
Sbjct: 967 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1026
Query: 586 EE 587
EE
Sbjct: 1027 EE 1028
Score = 47.6 bits (108), Expect = 1e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 261 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 320
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 321 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 374
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 375 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 434
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 435 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 494
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 495 KRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVE----AQLQELQVKFNEG 550
Query: 544 ER 545
ER
Sbjct: 551 ER 552
Score = 40.7 bits (91), Expect = 0.016
Identities = 71/293 (24%), Positives = 133/293 (45%), Gaps = 35/293 (11%)
Query: 343 KKTSHFESELYKTLDLAHD-------YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD 395
K S ES+L T +L + K KQ+++EK S EQL E + N +
Sbjct: 587 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAK---HNLE 643
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
K+I L + V + K++ D V LE A E ++ + ++ L++R ++E +
Sbjct: 644 KQIATL---HAQVADMKKKMEDSVGCLETAEEVKR----KLQKDLEGLSQR----HEEKV 692
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS--EVLKKCDFLDNEVKTLRQHLELQ 513
+ + K+++ +E V ++Q+ C+ + KK D L E KT+ +
Sbjct: 693 AAYDKLEKTKTRLQQELDDLLVDLDH--QRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 750
Query: 514 KNELKCH-YQKQLEDAVLAK-LQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILR 568
++ + +K+ + LA+ L+E EQ ER + R + +++ D K +
Sbjct: 751 RDRAEAEAREKETKALSLARALEEAMEQKAELER-LNKQFRTEMEDLMSSKDDVGKSVHE 809
Query: 569 IEEQHK-LEINVLEEK-QREEI--KLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E+ + LE V E K Q EE+ +L + A+ ++ L K + +R +G
Sbjct: 810 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 862
Score = 35.1 bits (77), Expect = 0.80
Identities = 63/314 (20%), Positives = 123/314 (39%), Gaps = 28/314 (8%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D K ++ I ++ + D ++ + + L A + + K K ++ E L+
Sbjct: 914 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 973
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDT---VMRLNKQLTDCVKNLEEALEKEKFAHD 434
E+L +D+ D + + + ++L + LEE LE+E+ +
Sbjct: 974 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTE 1033
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
+ + N +I +N + L ER + N QQL E+QN+ E+
Sbjct: 1034 LINDRLKKANLQIDQINAD---LNLERGHAQKNEN--------ARQQL-ERQNK--ELKV 1079
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME------ 548
K ++ VK+ + + E K ++ D + Q +Q+ R E++++
Sbjct: 1080 KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQV 1138
Query: 549 NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ--LAQAAEKLGLLE 606
+D R D +K R+++ + EE QR +LQ L A E +
Sbjct: 1139 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1198
Query: 607 SKVEC--QRRRRGE 618
+V + RRG+
Sbjct: 1199 REVSSLKNKLRRGD 1212
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 58.4 bits (135), Expect = 7e-08
Identities = 68/309 (22%), Positives = 143/309 (46%), Gaps = 47/309 (15%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
CE EN +++K E E+ + L + + ++ +NE + N E+ N
Sbjct: 29 CEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSN-- 86
Query: 389 VMLSNK-DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI 447
L NK + EI++ K T+ ++ Q D KNL L++ ++ N +L I
Sbjct: 87 --LRNKYETEINITK---TTIKEISMQKEDDSKNLRNQLDR------LSREN-RDLKDEI 134
Query: 448 QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
+ND L T++R R+ ++Q+ C SE+++K L+ E+K +
Sbjct: 135 VRLNDSILQATEQR---------RRAEENALQQKACG-----SEIMQKKQHLEIELKQVM 180
Query: 508 QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK---EN---NIVDS 561
Q Q++E +++ LE+A +Q+ ++++R + E + +A+ + EN + ++
Sbjct: 181 Q----QRSEDNARHKQSLEEAA-KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNN 235
Query: 562 FNKQILRIEEQHKLEINV-------LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++++I+ ++ Q + EIN+ L ++ E+ YR Q+ + L +++ +
Sbjct: 236 YDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKN 295
Query: 615 RRGETAARL 623
+T L
Sbjct: 296 TLTQTTENL 304
Score = 50.8 bits (116), Expect = 1e-05
Identities = 92/455 (20%), Positives = 185/455 (40%), Gaps = 30/455 (6%)
Query: 159 QPSSNKIYDRASRVLEQYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQ 218
+ + K + + L++ + K AT++ + QE +L +R E + ++
Sbjct: 374 ETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVK 433
Query: 219 NKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
++ I + SL EL K + NR + + + E E M
Sbjct: 434 DQDITRFQN---SLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQA 490
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFR--V 336
+ K + LR+ L L R + R ++ L ++ EVE R +
Sbjct: 491 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHL-REKQRTQEELRRLSSEVEALRRQL 549
Query: 337 VADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK 396
+ + K +H +E ++ +DK + L NE K E+L + +N+ ++
Sbjct: 550 LQEQESVKQAHLRNEHFQKA-----IEDKSRSL-NESKIEIERLQSLTENLTKEHLMLEE 603
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKN--LEEALEKEKFAHDST---KSNITELNKRIQSVN 451
E+ L+ YD + R + D KN + E + + +++ T + I +L + +++
Sbjct: 604 ELRNLRLEYDDLRR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLR 662
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
E ++ +++ E +++C + Q+ L K + + L++E+ +
Sbjct: 663 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 722
Query: 509 HLELQ---KNELKCHYQKQLEDAVLAKLQ--EFQEQLDRAEREMENDARLKEN--NIVDS 561
LE + K L+C Q+ D K Q +E + + E E E R K + + ++
Sbjct: 723 TLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIER 782
Query: 562 FNKQILRIEE--QHKLEINVLEEKQREEIKLYRLQ 594
+I RIEE + KLE + E + + E + R Q
Sbjct: 783 LQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQ 817
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/304 (18%), Positives = 127/304 (41%), Gaps = 25/304 (8%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA+++ E+E RV+ + + +E+EL K + + Y ++ L+N+ E ++N
Sbjct: 43 KAIKEKEYEIERLRVLLQEEGTRKREYENELAK---VRNHYNEEMSNLRNK---YETEIN 96
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
+ + K+ + L+ D + R N+ L D + L +++ + + N
Sbjct: 97 ITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENAL 156
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
+ ++ E + Q ++ +V ++RS E KQ+ E K +
Sbjct: 157 QQ----KACGSEIMQKKQHLEIELKQVMQQRS-----EDNARHKQS-LEEAAKTIQDKNK 206
Query: 502 EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS 561
E++ L+ + ++ + + Y+ +L + E++ + + E + + + I
Sbjct: 207 EIERLKAEFQ-EEAKRRWEYENELSKV----RNNYDEEIISLKNQFETEINITKTTI-HQ 260
Query: 562 FNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
Q ++ +I+ L + R EEIK + L Q E L +E ++ Q+ E
Sbjct: 261 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 320
Query: 619 TAAR 622
+ R
Sbjct: 321 VSQR 324
Score = 50.0 bits (114), Expect = 3e-05
Identities = 72/357 (20%), Positives = 158/357 (44%), Gaps = 51/357 (14%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K++ + L+E +++TN + E ++ ++ R V D ++ +
Sbjct: 474 KLEEELEGMRRSLKEQAIKITNLTQQLEQASI-VKKRSEDDLRQQRDVLDGHLREKQRTQ 532
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
EL + L+ + + +QL E++S++ Q + ++ + +K + ++ K + +
Sbjct: 533 EELRR---LSSEVEALRRQLLQEQESVK-QAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 588
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTK-----------SNITELNKRIQSVNDETLLLT 458
L + LT LEE L + +D + + I EL ++Q N+ TL L
Sbjct: 589 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 648
Query: 459 -------QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
+ER+ L+ ++ + + + ++ E +NQC++V+++ + L ++K L Q
Sbjct: 649 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQD-- 706
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
A+LQ +++L+RA+ +E + R+K+ ++ +QI
Sbjct: 707 ------------------KARLQRLEDELNRAKSTLEAETRVKQR--LECEKQQIQNDLN 746
Query: 572 QHKLEINVLE------EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
Q K + + E E +RE+ + + L E+L ++E + RR+ E + R
Sbjct: 747 QWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTR 803
Score = 46.0 bits (104), Expect = 4e-04
Identities = 66/332 (19%), Positives = 146/332 (43%), Gaps = 19/332 (5%)
Query: 314 DRAEDRHRKALEKMICEV-ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+R+ K L+ + + EN R V +D Q++ + + L + + + Q++ E
Sbjct: 283 NRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELR-QVTQMRTE 341
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLEEALEKE 429
+ +Q LD+ + +K+KEI+ LK+ D K L D ++ ++ L+K
Sbjct: 342 ESVRYKQ---SLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKA 398
Query: 430 KFAHDST-------KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ T + +T L + V+ E + Q+ ++ + E + + +E++L
Sbjct: 399 NSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 458
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ SE K L+ E++ +R+ L+ Q ++ + +QLE A + K + ++ L R
Sbjct: 459 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKI-TNLTQQLEQASIVK-KRSEDDL-R 515
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+R++ + ++ + + +E + + E ++ ++ Q A +
Sbjct: 516 QQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSR 575
Query: 603 GLLESKVECQR-RRRGETAARLHAALQAHWRH 633
L ESK+E +R + E + H L+ R+
Sbjct: 576 SLNESKIEIERLQSLTENLTKEHLMLEEELRN 607
Score = 40.3 bits (90), Expect = 0.021
Identities = 67/315 (21%), Positives = 137/315 (43%), Gaps = 29/315 (9%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R+ L +A + + K+ + + + D ++ + + K D+ +Q+ K
Sbjct: 390 RVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVS---QERTVKDQDITR-FQNSLK 445
Query: 368 QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK-QLTDCVKNLEEAL 426
+LQ +K+ +EE+LN L S K K+++ E ++ ++T+ + LE+A
Sbjct: 446 ELQLQKQKVEEELN-RLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQAS 504
Query: 427 EKEKFAHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + D + L+ + Q +E L+ E + L+ ++ +E+ ++Q
Sbjct: 505 IVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQES---VKQAHL 561
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
++ + K L+ + + L +N K H + E L L+ + L R
Sbjct: 562 RNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEE---LRNLRLEYDDLRRG 618
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLE----INVLE---EKQREEIKLYRLQLA 596
E ++D +N + Q L+I LE IN L+ E R+EI+ ++ Q
Sbjct: 619 RSEADSD----KNATILELRSQ-LQISNNRTLELQGLINDLQRERENLRQEIEKFQKQAL 673
Query: 597 QAAEKLGLLESKVEC 611
+A+ + + ESK +C
Sbjct: 674 EASNR--IQESKNQC 686
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/261 (18%), Positives = 119/261 (45%), Gaps = 15/261 (5%)
Query: 292 DRAKDAAISKLR-EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
D+++ SK+ E LT +L + + L + E ++ R +A +
Sbjct: 572 DKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATIL 631
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
EL L ++++ + + L N+ + E L E++ I K V++
Sbjct: 632 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQ 691
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL---LTQERDLLKSK 467
+ L +K LE+ + + D ELN+ ++ ET + L E+ +++
Sbjct: 692 ERESLLVKIKVLEQDKARLQRLED-------ELNRAKSTLEAETRVKQRLECEKQQIQND 744
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+N+ +++ + E+ + + +++ + ++ + L +E++ L+ E+++ E +C +++LED
Sbjct: 745 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQA--EIKRIEERC--RRKLED 800
Query: 528 AVLAKLQEFQEQLDRAEREME 548
+ + + + R +RE++
Sbjct: 801 STRETQSQLETERSRYQREID 821
>BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein.
Length = 627
Score = 58.4 bits (135), Expect = 7e-08
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 225 IDSDLLSLSELWGD--KAERTTGYNRGDKVDIIKLEEERLKRE---HCEAMIXXXXXXXX 279
+ S + S+ W K ER + K+ I K E+ R+ +E H + I
Sbjct: 179 LSSSMNSIKTFWSPELKKERALRKDEASKITIWK-EQYRVVQEENQHMQMTIQALQDELR 237
Query: 280 XXXXXXAVAMK--VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ + R + +++L E + ++ + + L K + E+E R+
Sbjct: 238 IQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME-LRI- 295
Query: 338 ADDAQKKTSHFESE-LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD--NVNVMLSNK 394
+ QK+T + E + K L++ K + + + E+ ++ +L K
Sbjct: 296 --ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQK 353
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+KE +L+E N + K L+ +E + S + + +L + IQ +
Sbjct: 354 EKENSMLREEMHRRFE-NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 455 LLLTQERD-------LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
L T+ER+ + +S +++ ++Q+L K + + K + L N+ +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 472
Query: 508 QHLELQKNELKCHYQK----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
QH+E+ K L Q+ Q E DA+ +L+E + L++ +++++ A K +
Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 532
Query: 563 N-KQILRIEEQHKLEINVLEEK---QREEIKLYRLQLAQAAEKLGLLES 607
+ K +L ++E+ ++NVL++K +E+++ Q++ E++ L++
Sbjct: 533 DLKDMLDVKER---KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQA 578
Score = 31.5 bits (68), Expect = 9.8
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
KKT + + A + D K + + K+ L +++N+ L +K+K++ LK
Sbjct: 512 KKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Query: 403 ENYDTVMRLNKQLTDCVKNLEEAL-EKEK 430
E ++ + LEEAL EKE+
Sbjct: 571 ERVKSLQADTTNTDTALTTLEEALAEKER 599
>AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen
MU-MB-20.201 protein.
Length = 681
Score = 58.4 bits (135), Expect = 7e-08
Identities = 83/384 (21%), Positives = 172/384 (44%), Gaps = 43/384 (11%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEK------MICEVENFRVVADDAQKKTSHFESELYK 354
+L+ RL + + + H K LE+ M E + + D + + E
Sbjct: 1 ELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKD 60
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI------------- 398
L+L D ++L+N K+ LE++LNT E+ ++ M+ ++ +
Sbjct: 61 KLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDS 120
Query: 399 -DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RIQSVNDE--- 453
+ L+ D K+ D + N+E LE+E+ H+ T + + E K ++ + +
Sbjct: 121 QERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI 180
Query: 454 --TLLLTQERDLLKSKV---NEERSRCAVIE-QQLCEKQNQCS--EVLKKCDFLDNEVKT 505
T L QE L+ ++ +EE + A+ + QL +++ + KK + L N++
Sbjct: 181 KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISL 240
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 241 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 299
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R +
Sbjct: 300 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEYEGKAM 358
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A+L++ H A+ +L HH
Sbjct: 359 LASLRSELNHQHAAAIDLLRHNHH 382
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 58.4 bits (135), Expect = 7e-08
Identities = 68/309 (22%), Positives = 143/309 (46%), Gaps = 47/309 (15%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
CE EN +++K E E+ + L + + ++ +NE + N E+ N
Sbjct: 1148 CEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSN-- 1205
Query: 389 VMLSNK-DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI 447
L NK + EI++ K T+ ++ Q D KNL L++ ++ N +L I
Sbjct: 1206 --LRNKYETEINITK---TTIKEISMQKEDDSKNLRNQLDR------LSREN-RDLKDEI 1253
Query: 448 QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
+ND L T++R R+ ++Q+ C SE+++K L+ E+K +
Sbjct: 1254 VRLNDSILQATEQR---------RRAEENALQQKACG-----SEIMQKKQHLEIELKQVM 1299
Query: 508 QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK---EN---NIVDS 561
Q Q++E +++ LE+A +Q+ ++++R + E + +A+ + EN + ++
Sbjct: 1300 Q----QRSEDNARHKQSLEEAA-KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNN 1354
Query: 562 FNKQILRIEEQHKLEINV-------LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++++I+ ++ Q + EIN+ L ++ E+ YR Q+ + L +++ +
Sbjct: 1355 YDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKN 1414
Query: 615 RRGETAARL 623
+T L
Sbjct: 1415 TLTQTTENL 1423
Score = 50.8 bits (116), Expect = 1e-05
Identities = 92/455 (20%), Positives = 185/455 (40%), Gaps = 30/455 (6%)
Query: 159 QPSSNKIYDRASRVLEQYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQ 218
+ + K + + L++ + K AT++ + QE +L +R E + ++
Sbjct: 1493 ETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVK 1552
Query: 219 NKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
++ I + SL EL K + NR + + + E E M
Sbjct: 1553 DQDITRFQN---SLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQA 1609
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFR--V 336
+ K + LR+ L L R + R ++ L ++ EVE R +
Sbjct: 1610 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHL-REKQRTQEELRRLSSEVEALRRQL 1668
Query: 337 VADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK 396
+ + K +H +E ++ +DK + L NE K E+L + +N+ ++
Sbjct: 1669 LQEQESVKQAHLRNEHFQKA-----IEDKSRSL-NESKIEIERLQSLTENLTKEHLMLEE 1722
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKN--LEEALEKEKFAHDST---KSNITELNKRIQSVN 451
E+ L+ YD + R + D KN + E + + +++ T + I +L + +++
Sbjct: 1723 ELRNLRLEYDDLRR-GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLR 1781
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
E ++ +++ E +++C + Q+ L K + + L++E+ +
Sbjct: 1782 QEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKS 1841
Query: 509 HLELQ---KNELKCHYQKQLEDAVLAKLQ--EFQEQLDRAEREMENDARLKEN--NIVDS 561
LE + K L+C Q+ D K Q +E + + E E E R K + + ++
Sbjct: 1842 TLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIER 1901
Query: 562 FNKQILRIEE--QHKLEINVLEEKQREEIKLYRLQ 594
+I RIEE + KLE + E + + E + R Q
Sbjct: 1902 LQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQ 1936
Score = 50.0 bits (114), Expect = 3e-05
Identities = 57/304 (18%), Positives = 127/304 (41%), Gaps = 25/304 (8%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA+++ E+E RV+ + + +E+EL K + + Y ++ L+N+ E ++N
Sbjct: 1162 KAIKEKEYEIERLRVLLQEEGTRKREYENELAK---VRNHYNEEMSNLRNK---YETEIN 1215
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
+ + K+ + L+ D + R N+ L D + L +++ + + N
Sbjct: 1216 ITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENAL 1275
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
+ ++ E + Q ++ +V ++RS E KQ+ E K +
Sbjct: 1276 QQ----KACGSEIMQKKQHLEIELKQVMQQRS-----EDNARHKQS-LEEAAKTIQDKNK 1325
Query: 502 EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS 561
E++ L+ + ++ + + Y+ +L + E++ + + E + + + I
Sbjct: 1326 EIERLKAEFQ-EEAKRRWEYENELSKV----RNNYDEEIISLKNQFETEINITKTTI-HQ 1379
Query: 562 FNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
Q ++ +I+ L + R EEIK + L Q E L +E ++ Q+ E
Sbjct: 1380 LTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSE 1439
Query: 619 TAAR 622
+ R
Sbjct: 1440 VSQR 1443
Score = 50.0 bits (114), Expect = 3e-05
Identities = 72/357 (20%), Positives = 158/357 (44%), Gaps = 51/357 (14%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K++ + L+E +++TN + E ++ ++ R V D ++ +
Sbjct: 1593 KLEEELEGMRRSLKEQAIKITNLTQQLEQASI-VKKRSEDDLRQQRDVLDGHLREKQRTQ 1651
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
EL + L+ + + +QL E++S++ Q + ++ + +K + ++ K + +
Sbjct: 1652 EELRR---LSSEVEALRRQLLQEQESVK-QAHLRNEHFQKAIEDKSRSLNESKIEIERLQ 1707
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTK-----------SNITELNKRIQSVNDETLLLT 458
L + LT LEE L + +D + + I EL ++Q N+ TL L
Sbjct: 1708 SLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQ 1767
Query: 459 -------QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
+ER+ L+ ++ + + + ++ E +NQC++V+++ + L ++K L Q
Sbjct: 1768 GLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQD-- 1825
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
A+LQ +++L+RA+ +E + R+K+ ++ +QI
Sbjct: 1826 ------------------KARLQRLEDELNRAKSTLEAETRVKQR--LECEKQQIQNDLN 1865
Query: 572 QHKLEINVLE------EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
Q K + + E E +RE+ + + L E+L ++E + RR+ E + R
Sbjct: 1866 QWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTR 1922
Score = 46.0 bits (104), Expect = 4e-04
Identities = 66/332 (19%), Positives = 146/332 (43%), Gaps = 19/332 (5%)
Query: 314 DRAEDRHRKALEKMICEV-ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+R+ K L+ + + EN R V +D Q++ + + L + + + Q++ E
Sbjct: 1402 NRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELR-QVTQMRTE 1460
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD---CVKNLEEALEKE 429
+ +Q LD+ + +K+KEI+ LK+ D K L D ++ ++ L+K
Sbjct: 1461 ESVRYKQ---SLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKA 1517
Query: 430 KFAHDST-------KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ T + +T L + V+ E + Q+ ++ + E + + +E++L
Sbjct: 1518 NSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEEL 1577
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ SE K L+ E++ +R+ L+ Q ++ + +QLE A + K + ++ L R
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKI-TNLTQQLEQASIVK-KRSEDDL-R 1634
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
+R++ + ++ + + +E + + E ++ ++ Q A +
Sbjct: 1635 QQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSR 1694
Query: 603 GLLESKVECQR-RRRGETAARLHAALQAHWRH 633
L ESK+E +R + E + H L+ R+
Sbjct: 1695 SLNESKIEIERLQSLTENLTKEHLMLEEELRN 1726
Score = 40.3 bits (90), Expect = 0.021
Identities = 67/315 (21%), Positives = 137/315 (43%), Gaps = 29/315 (9%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R+ L +A + + K+ + + + D ++ + + K D+ +Q+ K
Sbjct: 1509 RVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVS---QERTVKDQDITR-FQNSLK 1564
Query: 368 QLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK-QLTDCVKNLEEAL 426
+LQ +K+ +EE+LN L S K K+++ E ++ ++T+ + LE+A
Sbjct: 1565 ELQLQKQKVEEELN-RLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQAS 1623
Query: 427 EKEKFAHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + D + L+ + Q +E L+ E + L+ ++ +E+ ++Q
Sbjct: 1624 IVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQES---VKQAHL 1680
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
++ + K L+ + + L +N K H + E L L+ + L R
Sbjct: 1681 RNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEE---LRNLRLEYDDLRRG 1737
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLE----INVLE---EKQREEIKLYRLQLA 596
E ++D +N + Q L+I LE IN L+ E R+EI+ ++ Q
Sbjct: 1738 RSEADSD----KNATILELRSQ-LQISNNRTLELQGLINDLQRERENLRQEIEKFQKQAL 1792
Query: 597 QAAEKLGLLESKVEC 611
+A+ + + ESK +C
Sbjct: 1793 EASNR--IQESKNQC 1805
Score = 39.9 bits (89), Expect = 0.028
Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 31/223 (13%)
Query: 368 QLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
+L+N K + LEE+L D N NK+K +D + Y Q + +LEE
Sbjct: 1028 KLKNTKIEVLEEELRLARD-ANSENCNKNKFLDQNLQKYQAEC---SQFKAKLASLEELK 1083
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ + S K N+ + +I+ +N++ LT E + +E+ R +E + +++
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYE-------IEDEKRRRKSVEDRFDQQK 1136
Query: 487 NQCSEVLK--KCDFLDNEVKTLRQHLELQKNEL-KCHYQKQLEDAVLAKLQEFQEQLDRA 543
N ++ K +C+ +++L QK E K +K+ E + +L+ ++
Sbjct: 1137 NDYDQLQKARQCE---------KENLGWQKLESEKAIKEKEYE---IERLRVLLQEEGTR 1184
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
+RE EN+ N+ +N+++ + +++ EIN+ + +E
Sbjct: 1185 KREYENELAKVRNH----YNEEMSNLRNKYETEINITKTTIKE 1223
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/261 (18%), Positives = 119/261 (45%), Gaps = 15/261 (5%)
Query: 292 DRAKDAAISKLR-EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
D+++ SK+ E LT +L + + L + E ++ R +A +
Sbjct: 1691 DKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATIL 1750
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
EL L ++++ + + L N+ + E L E++ I K V++
Sbjct: 1751 ELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQ 1810
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL---LTQERDLLKSK 467
+ L +K LE+ + + D ELN+ ++ ET + L E+ +++
Sbjct: 1811 ERESLLVKIKVLEQDKARLQRLED-------ELNRAKSTLEAETRVKQRLECEKQQIQND 1863
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+N+ +++ + E+ + + +++ + ++ + L +E++ L+ E+++ E +C +++LED
Sbjct: 1864 LNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQA--EIKRIEERC--RRKLED 1919
Query: 528 AVLAKLQEFQEQLDRAEREME 548
+ + + + R +RE++
Sbjct: 1920 STRETQSQLETERSRYQREID 1940
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome
associated protein protein.
Length = 2442
Score = 58.4 bits (135), Expect = 7e-08
Identities = 66/306 (21%), Positives = 148/306 (48%), Gaps = 26/306 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
A ++ R AL+ + E E R + +K +H E++L K + + Q + +Q EK+
Sbjct: 635 AAEQARNALQVDLAEAEKRR---EALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEE 691
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDS 435
++++L+ ++ L++ + R + L V+ +EAL +EK A
Sbjct: 692 IQKKLSES-------RHQQEAATTQLEQLHQEAKRQEEVLARAVQE-KEALVREKAA--- 740
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK 495
+ + + + Q + + L+ ++LL+S + E + + +VI++ + + Q V +
Sbjct: 741 LEVRLQAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVTQA 800
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
+ + EV+ L+ L+ ++++ +Q DA +L + EQ + E + A KE
Sbjct: 801 KEVIQGEVRCLKLELDTERSQ-----AEQERDAAARQLAQ-AEQEGKTALEQQKAAHEKE 854
Query: 556 -NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
N + + + K+ R Q +L LE +RE+++L ++L + ++ ++++ E + R
Sbjct: 855 VNQLREKWEKE--RSWHQQEL-AKALESLEREKMEL-EMRLKEQQTEMEAIQAQRE-EER 909
Query: 615 RRGETA 620
+ E+A
Sbjct: 910 TQAESA 915
Score = 50.0 bits (114), Expect = 3e-05
Identities = 61/265 (23%), Positives = 116/265 (43%), Gaps = 20/265 (7%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLEEALE 427
+Q E + L+ +L+TE +++ ++ T + K + V L E E
Sbjct: 804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWE 863
Query: 428 KEKFAHDSTKSNITELNKRIQSVNDETLLLTQ-ERDLLKSKVNEERSRC--AVIEQQLCE 484
KE+ H + E +R + + L Q E + ++++ EER++ A+ + QL E
Sbjct: 864 KERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQL-E 922
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKLQEFQEQLDR 542
+ + +L+ E+ Q LE + ++K K+ E + +LQE Q +L
Sbjct: 923 TEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKE 982
Query: 543 AEREMEND-ARLKENNI------------VDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A R+ +D A L+E + V+ Q++ ++ +L ++EK RE +
Sbjct: 983 AARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQE 1042
Query: 590 LYRLQLAQAAEKLGLLESKVECQRR 614
R+Q EK L S +E ++R
Sbjct: 1043 YNRIQKELEREKASLTLSLMEKEQR 1067
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/268 (19%), Positives = 114/268 (42%), Gaps = 10/268 (3%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNL 422
Q + ++ + + + E+ L ++LD L+ +D+E++ L++ +++ + L
Sbjct: 1784 QQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADAL 1843
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
+ ALE+ + + ++ + + +E + + L+ + + R+ E+ L
Sbjct: 1844 QGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKAL 1903
Query: 483 CEKQNQCSEVLKKCDFLDNEVKT-LRQHLELQKNELKCHYQKQLEDAVLAKLQ--EFQEQ 539
Q QC+E + ++EV+T Q LQ + ++LE A+ A+ Q QE+
Sbjct: 1904 LALQQQCAEQAQ-----EHEVETRALQDSWLQAQAVLKERDQELE-ALRAESQSSRHQEE 1957
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
RA E +A K + + + +L E + + + + + Q
Sbjct: 1958 AARARAEALQEALGKAHAALQGKEQHLLEQAELSR-SLEASTATLQASLDACQAHSRQLE 2016
Query: 600 EKLGLLESKVECQRRRRGETAARLHAAL 627
E L + E +++ Q R E +L AL
Sbjct: 2017 EALRIQEGEIQDQDLRYQEDVQQLQQAL 2044
Score = 46.0 bits (104), Expect = 4e-04
Identities = 70/336 (20%), Positives = 141/336 (41%), Gaps = 29/336 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES--ELYKTLDLAHDYQDKCKQL 369
SL R + +L+++I ++ V D + S E+ EL ++ DYQD K L
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGLENSLELESSIFSQFDYQDADKAL 388
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+ L + D + L+ + +++L++ +D Q + K L + L+K
Sbjct: 389 TLVRSVLTRRRQAVQD-LRQQLAGCQEAVNLLQQQHD-------QWEEEGKALRQRLQKL 440
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
D+ +L + S L++ER+LL+ E R + V+EQ+ +
Sbjct: 441 TGERDTLAGQTVDLQGEVDS-------LSKERELLQKAREELRQQLEVLEQEAWRLRRVN 493
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL------EDAVLAKLQEFQEQLD-- 541
E+ + D + + ++ L L E + Q+ L + L++L +E L+
Sbjct: 494 VELQLQGDSAQGQKEEQQEELHLAVRERE-RLQEMLMGLEAKQSESLSELITLREALESI 552
Query: 542 RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
E E+ + + + + I + + + + +KL L A A +K
Sbjct: 553 HLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDK 612
Query: 602 LGLLESKVECQRRRRGETAARLHAALQAHWRHALRI 637
+GL + ++ + + +R+ AA QA R+AL++
Sbjct: 613 VGLNQQLLQLEEENQ-SVCSRMEAAEQA--RNALQV 645
Score = 44.4 bits (100), Expect = 0.001
Identities = 81/382 (21%), Positives = 158/382 (41%), Gaps = 35/382 (9%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMI-CEVENFRVVAD--DAQKKTSHFESELY 353
+A+ KL + + + D D+ +K E++ E E +V + D Q++ S + E
Sbjct: 1243 SALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKS 1302
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLN-TELDNVNVMLSNKDKEIDVLKENYDT-VMRL 411
K + + + +L SL+ +L EL + + + + KEN V L
Sbjct: 1303 KWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQ--GERELLQAAKENLTAQVEHL 1360
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ + A E+ + +S + N+ ++S + L ++ +L ++
Sbjct: 1361 QAAVVEARAQASAAGILEEDLR-TARSALKLKNEEVESERERAQALQEQGELKVAQGKAL 1419
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ----KQLED 527
+ A++ Q L E++ + + + L+ + + + LEL +LK Q +Q +
Sbjct: 1420 QENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQRE 586
L K + E L A +E E ++ I + R +++ LE +LE EK+ +
Sbjct: 1480 QELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKD---RETQRNVLEHQLLELEKKDQ 1536
Query: 587 EIKLYRLQLAQAAEKLGLLE----------SKVECQRR--------RRGETAARLHAALQ 628
I+ R Q+ ++L LE K+ECQ++ R + A H L
Sbjct: 1537 MIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLD 1596
Query: 629 AHWR-HALRILAAPHHDLGTHS 649
R L+ ++ HDL +HS
Sbjct: 1597 LEERSQELQAQSSQIHDLESHS 1618
Score = 36.7 bits (81), Expect = 0.26
Identities = 46/239 (19%), Positives = 101/239 (42%), Gaps = 18/239 (7%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES 350
++R K +L+E + ++ + R E +C+++ + +++ S E+
Sbjct: 880 LEREKMELEMRLKEQQTEM-EAIQAQREEERTQAESALCQMQ-----LETEKERVSLLET 933
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKK--SLEEQ-----LNTELDNVNVMLSNKDKE----ID 399
L +LA D + ++L+ + K L+EQ L T+L L ++ +
Sbjct: 934 LLQTQKELA-DASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLA 992
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
L+E ++++ L V++L+ L + + + + E + Q N L +
Sbjct: 993 ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELER 1052
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
E+ L + E+ R V+++ +Q + S + + E K L +EL + E+K
Sbjct: 1053 EKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 58.4 bits (135), Expect = 7e-08
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 225 IDSDLLSLSELWGD--KAERTTGYNRGDKVDIIKLEEERLKRE---HCEAMIXXXXXXXX 279
+ S + S+ W K ER + K+ I K E+ R+ +E H + I
Sbjct: 179 LSSSMNSIKTFWSPELKKERALRKDEASKITIWK-EQYRVVQEENQHMQMTIQALQDELR 237
Query: 280 XXXXXXAVAMK--VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ + R + +++L E + ++ + + L K + E+E R+
Sbjct: 238 IQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME-LRI- 295
Query: 338 ADDAQKKTSHFESE-LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD--NVNVMLSNK 394
+ QK+T + E + K L++ K + + + E+ ++ +L K
Sbjct: 296 --ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQK 353
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+KE +L+E N + K L+ +E + S + + +L + IQ +
Sbjct: 354 EKENSMLREEMHRRFE-NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 455 LLLTQERD-------LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
L T+ER+ + +S +++ ++Q+L K + + K + L N+ +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 472
Query: 508 QHLELQKNELKCHYQK----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
QH+E+ K L Q+ Q E DA+ +L+E + L++ +++++ A K +
Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 532
Query: 563 N-KQILRIEEQHKLEINVLEEK---QREEIKLYRLQLAQAAEKLGLLES 607
+ K +L ++E+ ++NVL++K +E+++ Q++ E++ L++
Sbjct: 533 DLKDMLDVKER---KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQA 578
Score = 48.0 bits (109), Expect = 1e-04
Identities = 66/281 (23%), Positives = 122/281 (43%), Gaps = 16/281 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
KKT + + A + D K + + K+ L +++N+ L +K+K++ LK
Sbjct: 512 KKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Query: 403 ENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
E ++ + LEEAL EKE+ T + E R + E + ++
Sbjct: 571 ERVKSLQADTTNTDTALTTLEEALAEKER-----TIERLKEQRDRDEREKQEE-IDNYKK 624
Query: 462 DL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LK 518
DL LK KV+ + + E L + + S + D+ +KTL LE +K E LK
Sbjct: 625 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 684
Query: 519 CHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
Q K+ +A L + + E DR + R K+ + ++ R+ E K
Sbjct: 685 MESQLKKAHEAAL-EARASPEMSDRIQHLEREITRYKDES--SKAQAEVDRLLEILKEVE 741
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
N +K ++ +L R Q+ +K+ L+ K + ++++ +
Sbjct: 742 NEKNDKDKKIAELER-QVKDQNKKVANLKHKEQVEKKKSAQ 781
Score = 40.7 bits (91), Expect = 0.016
Identities = 66/325 (20%), Positives = 138/325 (42%), Gaps = 16/325 (4%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+A++ L+E L +S +D K LE + E + + ++Q K +H E
Sbjct: 643 KEASLLDLKEHASSLASS-GLKKDSRLKTLE-IALEQKKEECLKMESQLKKAH---EAAL 697
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-VMRLNK 413
+ + D+ + L+ E +++ + V+ +L KE++ K + D + L +
Sbjct: 698 EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEIL-KEVENEKNDKDKKIAELER 756
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------ETLLLTQER-DLLKS 466
Q+ D K + KE+ + + E +R ++ND ++L +R + L+
Sbjct: 757 QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 816
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E A E L ++++ + K+ + L ++ ++Q LE K +L Q E
Sbjct: 817 ALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAE 876
Query: 527 -DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+ L L+ + + EM+ +A L + D+ N +L + K + +R
Sbjct: 877 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDA-NIALLELSSSKKKTQEEVAALKR 935
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
E+ +L + Q ++ L+ E
Sbjct: 936 EKDRLVQQLKQQTQNRMKLMADNYE 960
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 58.4 bits (135), Expect = 7e-08
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 225 IDSDLLSLSELWGD--KAERTTGYNRGDKVDIIKLEEERLKRE---HCEAMIXXXXXXXX 279
+ S + S+ W K ER + K+ I K E+ R+ +E H + I
Sbjct: 179 LSSSMNSIKTFWSPELKKERALRKDEASKITIWK-EQYRVVQEENQHMQMTIQALQDELR 237
Query: 280 XXXXXXAVAMK--VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ + R + +++L E + ++ + + L K + E+E R+
Sbjct: 238 IQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME-LRI- 295
Query: 338 ADDAQKKTSHFESE-LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD--NVNVMLSNK 394
+ QK+T + E + K L++ K + + + E+ ++ +L K
Sbjct: 296 --ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQK 353
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+KE +L+E N + K L+ +E + S + + +L + IQ +
Sbjct: 354 EKENSMLREEMHRRFE-NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 455 LLLTQERD-------LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
L T+ER+ + +S +++ ++Q+L K + + K + L N+ +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 472
Query: 508 QHLELQKNELKCHYQK----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
QH+E+ K L Q+ Q E DA+ +L+E + L++ +++++ A K +
Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 532
Query: 563 N-KQILRIEEQHKLEINVLEEK---QREEIKLYRLQLAQAAEKLGLLES 607
+ K +L ++E+ ++NVL++K +E+++ Q++ E++ L++
Sbjct: 533 DLKDMLDVKER---KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQA 578
Score = 50.0 bits (114), Expect = 3e-05
Identities = 67/282 (23%), Positives = 124/282 (43%), Gaps = 14/282 (4%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
KKT + + A + D K + + K+ L +++N+ L +K+K++ LK
Sbjct: 512 KKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Query: 403 ENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
E ++ + LEEAL EKE+ T + E R + E + ++
Sbjct: 571 ERVKSLQADTTNTDTALTTLEEALAEKER-----TIERLKEQRDRDEREKQEE-IDNYKK 624
Query: 462 DL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LK 518
DL LK KV+ + + E L + + S + D+ +KTL LE +K E LK
Sbjct: 625 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 684
Query: 519 CHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKLE 576
Q K+ +A L + + E DR + R K E++ + ++L I ++ + E
Sbjct: 685 MESQLKKAHEAAL-EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENE 743
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
N ++K E L Q+ +K+ L+ K + ++++ +
Sbjct: 744 KNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQ 785
Score = 42.3 bits (95), Expect = 0.005
Identities = 84/380 (22%), Positives = 154/380 (40%), Gaps = 46/380 (12%)
Query: 211 RESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAM 270
+E + +Q + ++ LL L E A ++G + ++ +++ E+ K+E C M
Sbjct: 630 KEKVSLLQGDLSEK-EASLLDLKEHASSLA--SSGLKKDSRLKTLEIALEQ-KKEECLKM 685
Query: 271 IXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICE 330
A DR I L R + +A+ + LE ++ E
Sbjct: 686 ESQLKKAHEAALEARASPEMSDR-----IQHLEREITRYKDESSKAQAEVDRLLE-ILKE 739
Query: 331 VENFRVVADDAQKKTSHFES--------ELYKTLDLAHDYQ---DKCKQLQNEKKSLEEQ 379
VEN + +D KK + ES + K +L H Q K Q+ E + E+
Sbjct: 740 VENEK---NDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 796
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSN 439
LN + L KD I+ L+E +R + Q+T E L +E+ A + +
Sbjct: 797 LNDSSQQLQDSLRKKDDRIEELEE----ALRESVQIT---AEREMVLAQEESARTNAEKQ 849
Query: 440 ITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL----CEKQNQCSEVLK- 494
+ EL ++ V QE + +K+K++ + A E L E++ EVL+
Sbjct: 850 VEELLMAMEKVK-------QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM 902
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK 554
K + L + ++ L EL +K+ ++ V A +E + + +++ +N +L
Sbjct: 903 KQEALLAAISEKDANIALL--ELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 959
Query: 555 ENNIVDSFNKQILRIEEQHK 574
+N D K + HK
Sbjct: 960 ADNYEDDHFKSSHSNQTNHK 979
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 58.4 bits (135), Expect = 7e-08
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 225 IDSDLLSLSELWGD--KAERTTGYNRGDKVDIIKLEEERLKRE---HCEAMIXXXXXXXX 279
+ S + S+ W K ER + K+ I K E+ R+ +E H + I
Sbjct: 190 LSSSMNSIKTFWSPELKKERALRKDEASKITIWK-EQYRVVQEENQHMQMTIQALQDELR 248
Query: 280 XXXXXXAVAMK--VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ + R + +++L E + ++ + + L K + E+E R+
Sbjct: 249 IQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME-LRI- 306
Query: 338 ADDAQKKTSHFESE-LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD--NVNVMLSNK 394
+ QK+T + E + K L++ K + + + E+ ++ +L K
Sbjct: 307 --ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQK 364
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+KE +L+E N + K L+ +E + S + + +L + IQ +
Sbjct: 365 EKENSMLREEMHRRFE-NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 423
Query: 455 LLLTQERD-------LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
L T+ER+ + +S +++ ++Q+L K + + K + L N+ +
Sbjct: 424 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 483
Query: 508 QHLELQKNELKCHYQK----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
QH+E+ K L Q+ Q E DA+ +L+E + L++ +++++ A K +
Sbjct: 484 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 543
Query: 563 N-KQILRIEEQHKLEINVLEEK---QREEIKLYRLQLAQAAEKLGLLES 607
+ K +L ++E+ ++NVL++K +E+++ Q++ E++ L++
Sbjct: 544 DLKDMLDVKER---KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQA 589
Score = 50.0 bits (114), Expect = 3e-05
Identities = 67/282 (23%), Positives = 124/282 (43%), Gaps = 14/282 (4%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
KKT + + A + D K + + K+ L +++N+ L +K+K++ LK
Sbjct: 523 KKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 581
Query: 403 ENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
E ++ + LEEAL EKE+ T + E R + E + ++
Sbjct: 582 ERVKSLQADTTNTDTALTTLEEALAEKER-----TIERLKEQRDRDEREKQEE-IDNYKK 635
Query: 462 DL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LK 518
DL LK KV+ + + E L + + S + D+ +KTL LE +K E LK
Sbjct: 636 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 695
Query: 519 CHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKLE 576
Q K+ +A L + + E DR + R K E++ + ++L I ++ + E
Sbjct: 696 MESQLKKAHEAAL-EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENE 754
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
N ++K E L Q+ +K+ L+ K + ++++ +
Sbjct: 755 KNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQ 796
Score = 42.3 bits (95), Expect = 0.005
Identities = 84/380 (22%), Positives = 154/380 (40%), Gaps = 46/380 (12%)
Query: 211 RESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAM 270
+E + +Q + ++ LL L E A ++G + ++ +++ E+ K+E C M
Sbjct: 641 KEKVSLLQGDLSEK-EASLLDLKEHASSLA--SSGLKKDSRLKTLEIALEQ-KKEECLKM 696
Query: 271 IXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICE 330
A DR I L R + +A+ + LE ++ E
Sbjct: 697 ESQLKKAHEAALEARASPEMSDR-----IQHLEREITRYKDESSKAQAEVDRLLE-ILKE 750
Query: 331 VENFRVVADDAQKKTSHFES--------ELYKTLDLAHDYQ---DKCKQLQNEKKSLEEQ 379
VEN + +D KK + ES + K +L H Q K Q+ E + E+
Sbjct: 751 VENEK---NDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDN 807
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSN 439
LN + L KD I+ L+E +R + Q+T E L +E+ A + +
Sbjct: 808 LNDSSQQLQDSLRKKDDRIEELEE----ALRESVQIT---AEREMVLAQEESARTNAEKQ 860
Query: 440 ITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL----CEKQNQCSEVLK- 494
+ EL ++ V QE + +K+K++ + A E L E++ EVL+
Sbjct: 861 VEELLMAMEKVK-------QELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM 913
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK 554
K + L + ++ L EL +K+ ++ V A +E + + +++ +N +L
Sbjct: 914 KQEALLAAISEKDANIALL--ELSSS-KKKTQEEVAALKREKDRLVQQLKQQTQNRMKLM 970
Query: 555 ENNIVDSFNKQILRIEEQHK 574
+N D K + HK
Sbjct: 971 ADNYEDDHFKSSHSNQTNHK 990
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 58.4 bits (135), Expect = 7e-08
Identities = 81/409 (19%), Positives = 178/409 (43%), Gaps = 35/409 (8%)
Query: 225 IDSDLLSLSELWGD--KAERTTGYNRGDKVDIIKLEEERLKRE---HCEAMIXXXXXXXX 279
+ S + S+ W K ER + K+ I K E+ R+ +E H + I
Sbjct: 179 LSSSMNSIKTFWSPELKKERALRKDEASKITIWK-EQYRVVQEENQHMQMTIQALQDELR 237
Query: 280 XXXXXXAVAMK--VDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ + R + +++L E + ++ + + L K + E+E R+
Sbjct: 238 IQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME-LRI- 295
Query: 338 ADDAQKKTSHFESE-LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD--NVNVMLSNK 394
+ QK+T + E + K L++ K + + + E+ ++ +L K
Sbjct: 296 --ETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQK 353
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+KE +L+E N + K L+ +E + S + + +L + IQ +
Sbjct: 354 EKENSMLREEMHRRFE-NAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNG 412
Query: 455 LLLTQERD-------LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
L T+ER+ + +S +++ ++Q+L K + + K + L N+ +
Sbjct: 413 ALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSK 472
Query: 508 QHLELQKNELKCHYQK----QLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
QH+E+ K L Q+ Q E DA+ +L+E + L++ +++++ A K +
Sbjct: 473 QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIH 532
Query: 563 N-KQILRIEEQHKLEINVLEEK---QREEIKLYRLQLAQAAEKLGLLES 607
+ K +L ++E+ ++NVL++K +E+++ Q++ E++ L++
Sbjct: 533 DLKDMLDVKER---KVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQA 578
Score = 50.0 bits (114), Expect = 3e-05
Identities = 67/282 (23%), Positives = 124/282 (43%), Gaps = 14/282 (4%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK 402
KKT + + A + D K + + K+ L +++N+ L +K+K++ LK
Sbjct: 512 KKTKQIQDMAEEKGTQAGEIHD-LKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLK 570
Query: 403 ENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
E ++ + LEEAL EKE+ T + E R + E + ++
Sbjct: 571 ERVKSLQADTTNTDTALTTLEEALAEKER-----TIERLKEQRDRDEREKQEE-IDNYKK 624
Query: 462 DL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LK 518
DL LK KV+ + + E L + + S + D+ +KTL LE +K E LK
Sbjct: 625 DLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLK 684
Query: 519 CHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKLE 576
Q K+ +A L + + E DR + R K E++ + ++L I ++ + E
Sbjct: 685 MESQLKKAHEAAL-EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENE 743
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
N ++K E L Q+ +K+ L+ K + ++++ +
Sbjct: 744 KNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQ 785
Score = 39.1 bits (87), Expect = 0.049
Identities = 59/286 (20%), Positives = 129/286 (45%), Gaps = 29/286 (10%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
+ A+ + +E L++ + L +A H ALE + R+ +++ + ++ E K
Sbjct: 672 EIALEQKKEECLKMESQLKKA---HEAALEARASPEMSDRI--QHLEREITRYKDESSKA 726
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNV-MLSNKDKEIDVLKENYDTVMRLNKQ 414
+ K+++NEK ++++ EL+++ + +++K++ LK + + Q
Sbjct: 727 QAEVDRLLEILKEVENEKNDKDKKI-AELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQ 785
Query: 415 LTDCVKNLEEALEKEKFAHDSTKS-NITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
+ LEEA +E +DS++ + EL ++ V QE + +K+K++ +
Sbjct: 786 M------LEEARRREDNLNDSSQQLQVEELLMAMEKVK-------QELESMKAKLSSTQQ 832
Query: 474 RCAVIEQQL----CEKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
A E L E++ EVL+ K + L + ++ L EL +K+ ++
Sbjct: 833 SLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL--ELSSS-KKKTQEE 889
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
V A +E + + +++ +N +L +N D K + HK
Sbjct: 890 VAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHK 935
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 58.0 bits (134), Expect = 1e-07
Identities = 57/265 (21%), Positives = 125/265 (47%), Gaps = 12/265 (4%)
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
+ ++K L EK L+ Q+ E DN+N D+ I + V +N++L D +
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEE 933
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
E K++ D +EL K I + + +E+ ++KV A +++
Sbjct: 934 MNAELTAKKRKLEDEC----SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 989
Query: 481 QLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE 538
+ + K+ + + + D +V+ + + L K+++K Q + L + ++ +
Sbjct: 990 IIAKLTKEKKALQEAHQQALDDLQVEEDKVN-SLSKSKVKLEQQVDDLEGSLEQEKKVRM 1048
Query: 539 QLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
L+RA+R++E D +L + +I+D N ++ E+ K E ++ ++ + E+ + LQL +
Sbjct: 1049 DLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQK 1108
Query: 598 AAE----KLGLLESKVECQRRRRGE 618
+ ++ LE ++E +R R +
Sbjct: 1109 KLKENQARIEELEEELEAERTARAK 1133
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/299 (22%), Positives = 134/299 (44%), Gaps = 22/299 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1443 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1502
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK- 430
E K+L+E E+ ++ L K + L+ ++ KQL L+ ALE+ +
Sbjct: 1503 ENKNLQE----EISDLTEQLGEGGKNVHELE-------KVRKQLEVEKLELQSALEEAEA 1551
Query: 431 -FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
H+ K +L E L ++ ++ ++K N +R ++ L +
Sbjct: 1552 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV-VDSLQTSLDAETRSR 1610
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
+EVL+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R N
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AN 1666
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
D LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1667 D-DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1721
Score = 50.8 bits (116), Expect = 1e-05
Identities = 41/213 (19%), Positives = 104/213 (48%), Gaps = 7/213 (3%)
Query: 391 LSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
++ +E +KE + K+L + + +L + + + + N+ + +R +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 451 NDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL 510
+ L + + ++ +E A + + + +++CSE+ K D L+ + + +
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 511 ELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+N++K ++ D ++AKL + ++ L A ++ +D +++E+ V+S +K +++
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDK-VNSLSKSKVKL 1029
Query: 570 EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
E+Q ++ LE +E K+ R+ L +A KL
Sbjct: 1030 EQQ----VDDLEGSLEQEKKV-RMDLERAKRKL 1057
Score = 43.6 bits (98), Expect = 0.002
Identities = 71/417 (17%), Positives = 173/417 (41%), Gaps = 38/417 (9%)
Query: 171 RVLEQYKASYSKNKPGATDSYSASSNQELKLPEMR-PFGENRESLKFIQNKYIDTIDSDL 229
++L ++K Y +++ S + + +L +++ + E+ E L+ + + + ++
Sbjct: 1453 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN-KNLQEEI 1511
Query: 230 LSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAM 289
L+E G+ + + K +LE E+L+ + A+ +
Sbjct: 1512 SDLTEQLGEGGKNVHELEKVRK----QLEVEKLELQ--SALEEAEASLEHEEGKILRAQL 1565
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
+ ++ K KL E +++A+ H++ ++ + ++ ++ + E
Sbjct: 1566 EFNQIKAEIERKLAEK----DEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKME 1621
Query: 350 SELYKT-LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+L + + L+H + + Q + KSL+ L + + L + + D LKEN V
Sbjct: 1622 GDLNEMEIQLSHANR-MAAEAQKQVKSLQSLLK----DTQIQLDDAVRANDDLKENIAIV 1676
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
R N L ++ L +E+ + + + + E ++R+Q LL +Q L+ K
Sbjct: 1677 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ------LLHSQNTSLINQKK 1730
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
+E L + Q++ E +++C + + K + ELK E
Sbjct: 1731 K--------MESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELK------KEQD 1776
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
A L+ ++ +++ +++++ E + KQ+ ++E + + LE +Q+
Sbjct: 1777 TSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Score = 42.7 bits (96), Expect = 0.004
Identities = 55/278 (19%), Positives = 123/278 (44%), Gaps = 21/278 (7%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-------QLNT 382
++++ + +K+ E+++ + + +L EKK+L+E L
Sbjct: 955 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQV 1014
Query: 383 ELDNVNVMLSNK---DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALE--KEKFAH-DST 436
E D VN + +K ++++D L+ + + ++ L + LE L+ +E ++
Sbjct: 1015 EEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEND 1074
Query: 437 KSNITE-LNKRIQSVNDETLLLTQERDL---LKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
K + E L K+ +N + + E+ L L+ K+ E ++R +E++L ++ ++V
Sbjct: 1075 KLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKV 1134
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
K L E++ + + LE Q ++ A+ Q+ + L+ A + E A
Sbjct: 1135 EKLRSDLSRELEEISERLEEAGGATS--VQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1192
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
DS + +I+ +++ + EK++ E KL
Sbjct: 1193 ALRKKHADSVAELGEQIDNLQRVKQKL--EKEKSEFKL 1228
Score = 34.7 bits (76), Expect = 1.1
Identities = 70/332 (21%), Positives = 138/332 (41%), Gaps = 38/332 (11%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1124 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1180
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E TL ++ L+ + +L ++DN+ + +KE K D V
Sbjct: 1181 EEA---TLQ----HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+Q+ NLE+ + D +L + +S+ND T TQ ++K+
Sbjct: 1234 TSNMEQIIKAKANLEKV---SRTLEDQANEYRVKLEEAQRSLNDFT---TQ-----RAKL 1282
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
E A +QL EK+ S++ + +++ L++ LE + + ++A
Sbjct: 1283 QTENGELA---RQLEEKEALISQLTRGKLSYTQQMEDLKRQLE---------EEGKAKNA 1330
Query: 529 VLAKLQEFQEQLD--RAEREMENDARLKENNIVDSFNKQILRIEEQHKLE-INVLEEKQR 585
+ LQ + D R + E E +A+ + ++ N ++ + +++ + I EE +
Sbjct: 1331 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEE 1390
Query: 586 EEIKL-YRLQLA-QAAEKLGLLESKVECQRRR 615
+ KL RLQ A +A E + S +E + R
Sbjct: 1391 AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR 1422
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 58.0 bits (134), Expect = 1e-07
Identities = 60/266 (22%), Positives = 124/266 (46%), Gaps = 14/266 (5%)
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
+ ++K L EK L+ Q+ E DN+N D+ I + V +N++L D +
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEE 933
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN---EERSRCAV 477
E K++ D +EL K I + + +E+ ++KV EE +
Sbjct: 934 MNAELTAKKRKLEDEC----SELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDE 989
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
I +L +++ E ++ LD+ + L K+++K Q + L + ++ +
Sbjct: 990 IIAKLTKEKKALQEAHQQA--LDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVR 1047
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
L+RA+R++E D +L + +I+D N ++ E+ K E ++ ++ + E++ +LQ
Sbjct: 1048 MDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQ 1107
Query: 595 --LAQAAEKLGLLESKVECQRRRRGE 618
L + ++ LE ++E +R R +
Sbjct: 1108 KKLKENQARIEELEEELEAERTARAK 1133
Score = 53.2 bits (122), Expect = 3e-06
Identities = 66/299 (22%), Positives = 134/299 (44%), Gaps = 22/299 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1443 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1502
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK- 430
E K+L+E E+ ++ L K + L+ ++ KQL L+ ALE+ +
Sbjct: 1503 ENKNLQE----EISDLTEQLGEGGKNVHELE-------KVRKQLEVEKLELQSALEEAEA 1551
Query: 431 -FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
H+ K +L E L ++ ++ ++K N +R ++ L +
Sbjct: 1552 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRV-VDSLQTSLDAETRSR 1610
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
+EVL+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R N
Sbjct: 1611 NEVLRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AN 1666
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
D LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1667 D-DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLADRELIETSERVQLLHSQ 1721
Score = 48.8 bits (111), Expect = 6e-05
Identities = 40/213 (18%), Positives = 103/213 (48%), Gaps = 7/213 (3%)
Query: 391 LSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
++ +E +KE + K+L + + +L + + + + N+ + +R +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 451 NDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL 510
+ L + + ++ +E A + + + +++CSE+ K D L+ + + +
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEK 970
Query: 511 ELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+N++K ++ D ++AKL + ++ L A ++ +D + +E+ V++ +K +++
Sbjct: 971 HATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK-VNTLSKSKVKL 1029
Query: 570 EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
E+Q ++ LE +E K+ R+ L +A KL
Sbjct: 1030 EQQ----VDDLEGSLEQEKKV-RMDLERAKRKL 1057
Score = 45.6 bits (103), Expect = 6e-04
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + + +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1589
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + ++ KK +E LN +L + N M + K++
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + D L
Sbjct: 1650 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLADREL 1708
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q++ E +++C + + K H +
Sbjct: 1709 IETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITHAAMMA 1768
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1769 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1822
Query: 575 LEINVLEEKQR 585
LE +Q+
Sbjct: 1823 ELEGELEAEQK 1833
Score = 35.9 bits (79), Expect = 0.46
Identities = 71/332 (21%), Positives = 139/332 (41%), Gaps = 38/332 (11%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1124 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1180
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E TL ++ L+ + +L ++DN+ + +KE K D V
Sbjct: 1181 EEA---TLQ----HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1233
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+Q+ NLE+ + D +L + +S+ND T +R L+++
Sbjct: 1234 TSNMEQIIKAKANLEKV---SRTLEDQANEYRVKLEEAQRSLND----FTTQRAKLQTE- 1285
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
N E SR QL EK+ S++ + +++ L++ LE + + ++A
Sbjct: 1286 NGELSR------QLEEKEALISQLTRGKLSYTQQMEDLKRQLE---------EEGKAKNA 1330
Query: 529 VLAKLQEFQEQLD--RAEREMENDARLKENNIVDSFNKQILRIEEQHKLE-INVLEEKQR 585
+ LQ + D R + E E +A+ + ++ N ++ + +++ + I EE +
Sbjct: 1331 LAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEE 1390
Query: 586 EEIKL-YRLQLA-QAAEKLGLLESKVECQRRR 615
+ KL RLQ A +A E + S +E + R
Sbjct: 1391 AKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHR 1422
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 1e-07
Identities = 73/328 (22%), Positives = 154/328 (46%), Gaps = 30/328 (9%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
+ D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKC----- 519
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 520 HYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
Y+ +QLE+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEE 925
Query: 577 INVLEEKQR--EEIKLYRLQLAQAAEKL 602
E+ +R E++ R L + EKL
Sbjct: 926 SEQKEQLRRLKNEMENERWHLGKTIEKL 953
Score = 54.0 bits (124), Expect = 2e-06
Identities = 67/325 (20%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 952 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
E+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 1012 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 1060
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ + +E LL+ +
Sbjct: 1061 RLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE---------LLQERAA 1111
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 1112 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 1152
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 1153 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 1209
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/348 (21%), Positives = 149/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 811 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 866
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 867 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 926
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 985
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M+++ RL E + D Q + ++ LE +
Sbjct: 986 --LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQRRRRGETAARL 623
E + + +K R +L Q +K+ LE ++E +R + R+
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 1e-07
Identities = 73/328 (22%), Positives = 154/328 (46%), Gaps = 30/328 (9%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
+ D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKC----- 519
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 520 HYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
Y+ +QLE+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEE 925
Query: 577 INVLEEKQR--EEIKLYRLQLAQAAEKL 602
E+ +R E++ R L + EKL
Sbjct: 926 SEQKEQLRRLKNEMENERWHLGKTIEKL 953
Score = 54.0 bits (124), Expect = 2e-06
Identities = 67/325 (20%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 952 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
E+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 1012 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 1060
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ + +E LL+ +
Sbjct: 1061 RLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE---------LLQERAA 1111
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 1112 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 1152
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 1153 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 1209
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/348 (21%), Positives = 149/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 811 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 866
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 867 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 926
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 985
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M+++ RL E + D Q + ++ LE +
Sbjct: 986 --LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQRRRRGETAARL 623
E + + +K R +L Q +K+ LE ++E +R + R+
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
>BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein.
Length = 703
Score = 58.0 bits (134), Expect = 1e-07
Identities = 70/335 (20%), Positives = 151/335 (45%), Gaps = 20/335 (5%)
Query: 291 VDRAKDAAISKLREAWLRLTNSLDRAED---RHRKALEKMICEVENFRVVADDAQKKTSH 347
++ AK A+ ++ + L + E+ K + C+++ + ++ K+
Sbjct: 40 IEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDV 99
Query: 348 FESELYK-TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
++ TL + + Q +C QN+ K +Q+NT L L ++ + +K N +
Sbjct: 100 LNEDVRNLTLKIEQETQKRCLT-QNDLKMQTQQVNT-LKMSEKQLKQENNHLMEMKMNLE 157
Query: 407 TV-MRLNKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD 462
L K+ D +K L++ LE E++ K+ + EL + + E L +E
Sbjct: 158 KQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECE----EKTKLGKELQ 213
Query: 463 LLKSKVNEER-SRCAVIEQQLCEKQN-QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
K ++ +ER S A +E L + + Q + + + + D E + + + LE+ K + H
Sbjct: 214 QKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEI-KEMMARH 272
Query: 521 YQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
Q+ E DA +A L+E L + N+ + + NN + +Q+ R++++ ++
Sbjct: 273 KQELTEKDATIASLEETNRTLTSDVANLANE-KEELNNKLKDVQEQLSRLKDE-EISAAA 330
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
++ + +++ R QA KL + ++ E +R
Sbjct: 331 IKAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKR 365
Score = 54.4 bits (125), Expect = 1e-06
Identities = 60/234 (25%), Positives = 113/234 (48%), Gaps = 25/234 (10%)
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND--ETLLLTQERDL-----LKSK 467
+T +K ++++LE+E+ H +TK+ + + NK +S+ + + E+ L LK K
Sbjct: 5 MTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQK 64
Query: 468 VN----EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
V E RC++++ L + Q + +E+LK+ D L+ +V+ L +E Q+ + +C Q
Sbjct: 65 VENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIE-QETQKRCLTQN 123
Query: 524 QL--EDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
L + + L+ ++QL + ME L++ N K+ + Q K E+
Sbjct: 124 DLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNA--ELRKERQDADGQMK-ELQDQ 180
Query: 581 EEKQREEIKLYRLQLAQAAE------KLGL-LESKVECQRRRRGETAARLHAAL 627
E ++ LY+ Q+ + E KLG L+ K + + R AA+L L
Sbjct: 181 LEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITL 234
Score = 43.6 bits (98), Expect = 0.002
Identities = 55/272 (20%), Positives = 130/272 (47%), Gaps = 18/272 (6%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ-LNTELDNVNVMLSNKDKEIDV-LKENYD 406
++++Y++++ A + K++ EKK LEE+ L +++N+ + + +D LK++
Sbjct: 33 KNKIYESIEEAKS--EAMKEM--EKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQ 88
Query: 407 TVMRLNKQ---LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD- 462
+ L KQ L + V+NL +E+E T++++ +++ ++ L QE +
Sbjct: 89 KINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNH 148
Query: 463 LLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ 522
L++ K+N E+ A + ++ + Q E+ + + + TL + ++++ + +C +
Sbjct: 149 LMEMKMNLEKQN-AELRKERQDADGQMKELQDQLE-AEQYFSTLYK-TQVRELKEECEEK 205
Query: 523 KQLEDAVLAKLQEFQEQLDRAEREME-----NDARLKENNIVDSFNKQILRIEEQHKLEI 577
+L + K QE Q++ D ++E D+ +I + + + + +LEI
Sbjct: 206 TKLGKELQQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEI 265
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
+ + ++E+ +A E L S V
Sbjct: 266 KEMMARHKQELTEKDATIASLEETNRTLTSDV 297
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 58.0 bits (134), Expect = 1e-07
Identities = 73/328 (22%), Positives = 154/328 (46%), Gaps = 30/328 (9%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
+ D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKC----- 519
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 520 HYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
Y+ +QLE+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEE 925
Query: 577 INVLEEKQR--EEIKLYRLQLAQAAEKL 602
E+ +R E++ R L + EKL
Sbjct: 926 SEQKEQLRRLKNEMENERWHLGKTIEKL 953
Score = 54.0 bits (124), Expect = 2e-06
Identities = 67/325 (20%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 952 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
E+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 1012 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 1060
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ + +E LL+ +
Sbjct: 1061 RLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE---------LLQERAA 1111
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 1112 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 1152
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 1153 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 1209
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/348 (21%), Positives = 149/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 811 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 866
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 867 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 926
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 985
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M+++ RL E + D Q + ++ LE +
Sbjct: 986 --LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQRRRRGETAARL 623
E + + +K R +L Q +K+ LE ++E +R + R+
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
>BC062749-1|AAH62749.1| 383|Homo sapiens CCDC73 protein protein.
Length = 383
Score = 58.0 bits (134), Expect = 1e-07
Identities = 58/296 (19%), Positives = 132/296 (44%), Gaps = 24/296 (8%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
+S++ + + +T ++ H K LE+ + E KK E+E+ L
Sbjct: 75 LSEIEKYYATITGQFGLVKENHEK-LEQNVREAIQSNKRLSALNKKQ---EAEI---CSL 127
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+ + L K + + ++ E N+ L+ K+++ L+E + + LN+++ +
Sbjct: 128 KKELKKAASDLIKSKVTCQYKMGEE----NINLTIKEQKFQELQERLNMELELNEKINEE 183
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVI 478
+ +++E EK++ ++N TE+ ++ + + L ++ +L + KV E + +
Sbjct: 184 ITHIQE--EKQQLLRQQIQAN-TEMEAELKVLKENNQTLERDNELQREKVKENEEKFLNL 240
Query: 479 ----EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ-HLELQKNELKCHYQKQLEDAVLAKL 533
E+ L + E+ + + + NE+ +L++ H++LQ+ HY K +
Sbjct: 241 QNEHEKALGTWKRHAEELNGEINKIKNELSSLKETHIKLQE-----HYNKLCNQKTFEED 295
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
++FQ + E EN I+ +N + EE + + E +++EE K
Sbjct: 296 KKFQNVPEVNNENSEMSTEKSENTIIQKYNTEQEIREENMENFCSDTEYREKEEKK 351
Score = 51.6 bits (118), Expect = 9e-06
Identities = 61/253 (24%), Positives = 116/253 (45%), Gaps = 22/253 (8%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
KQLQ + +LEE E + K+KEI+ LKE + L V +E+ +
Sbjct: 6 KQLQMKMCALEE----EKGKYQLATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKV 61
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+ A + ++E+ K ++ + L+ + + L+ V E A+ +
Sbjct: 62 QLHLLAKEDYHKQLSEIEKYYATITGQFGLVKENHEKLEQNVRE-----AIQSNKRLSAL 116
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLA-KLQEFQEQLDRAER 545
N+ E + C L E+K + +L K+++ C Y+ E+ L K Q+FQE +R
Sbjct: 117 NKKQEA-EICS-LKKELK--KAASDLIKSKVTCQYKMGEENINLTIKEQKFQELQERLNM 172
Query: 546 EMENDARLKEN-NIVDSFNKQILRIEEQ----HKLEINVLEEKQR---EEIKLYRLQLAQ 597
E+E + ++ E + +Q+LR + Q + E+ VL+E + + +L R ++ +
Sbjct: 173 ELELNEKINEEITHIQEEKQQLLRQQIQANTEMEAELKVLKENNQTLERDNELQREKVKE 232
Query: 598 AAEKLGLLESKVE 610
EK L+++ E
Sbjct: 233 NEEKFLNLQNEHE 245
Score = 45.6 bits (103), Expect = 6e-04
Identities = 54/257 (21%), Positives = 111/257 (43%), Gaps = 18/257 (7%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
A + K +E + ++ +V QKK S E ++ L DY + +++ +
Sbjct: 25 ATEIKEKEIEGLKETLKALQVSKYSLQKKVSEMEQKVQLHLLAKEDYHKQLSEIEKYYAT 84
Query: 376 LEEQLNTELDNVNVMLSN------KDKEIDVLKENYDT-VMRLNKQLTDCVKNLEEALEK 428
+ Q +N + N +K + L + + + L K+L +L ++
Sbjct: 85 ITGQFGLVKENHEKLEQNVREAIQSNKRLSALNKKQEAEICSLKKELKKAASDLIKSKVT 144
Query: 429 EKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
++ N+T ++ Q + + L E + L K+NEE + +QQL +Q Q
Sbjct: 145 CQYKMGEENINLTIKEQKFQELQER---LNMELE-LNEKINEEITHIQEEKQQLLRQQIQ 200
Query: 489 C-SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL-----EDAVLAKLQEFQEQLDR 542
+E+ + L +TL + ELQ+ ++K + +K L + L + E+L+
Sbjct: 201 ANTEMEAELKVLKENNQTLERDNELQREKVKENEEKFLNLQNEHEKALGTWKRHAEELNG 260
Query: 543 AEREMEND-ARLKENNI 558
+++N+ + LKE +I
Sbjct: 261 EINKIKNELSSLKETHI 277
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 58.0 bits (134), Expect = 1e-07
Identities = 73/328 (22%), Positives = 154/328 (46%), Gaps = 30/328 (9%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
+ D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 748 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKC----- 519
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 520 HYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
Y+ +QLE+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEE 925
Query: 577 INVLEEKQR--EEIKLYRLQLAQAAEKL 602
E+ +R E++ R L + EKL
Sbjct: 926 SEQKEQLRRLKNEMENERWHLGKTIEKL 953
Score = 54.0 bits (124), Expect = 2e-06
Identities = 67/325 (20%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 952 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
E+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 1012 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 1060
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ + +E LL+ +
Sbjct: 1061 RLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNE---------LLQERAA 1111
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 1112 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 1152
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 1153 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 1209
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/348 (21%), Positives = 149/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 811 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 866
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 867 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 926
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 985
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M+++ RL E + D Q + ++ LE +
Sbjct: 986 --LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQRRRRGETAARL 623
E + + +K R +L Q +K+ LE ++E +R + R+
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 1091
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 58.0 bits (134), Expect = 1e-07
Identities = 73/328 (22%), Positives = 154/328 (46%), Gaps = 30/328 (9%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 373 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 432
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 433 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 492
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
+ D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 493 EQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 552
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKC----- 519
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K
Sbjct: 553 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 612
Query: 520 HYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
Y+ +QLE+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E
Sbjct: 613 KYEGEIRQLEEALVHARKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEE 670
Query: 577 INVLEEKQR--EEIKLYRLQLAQAAEKL 602
E+ +R E++ R L + EKL
Sbjct: 671 SEQKEQLRRLKNEMENERWHLGKTIEKL 698
Score = 55.2 bits (127), Expect = 7e-07
Identities = 68/325 (20%), Positives = 143/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 697 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 756
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
E+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 757 DEMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 805
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ V +E LL+ +
Sbjct: 806 RLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQVRNE---------LLQERAA 856
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 857 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 897
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 898 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 954
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 955 AMKRQVEEAEEEIDRLESSKKKLQR 979
Score = 46.0 bits (104), Expect = 4e-04
Identities = 75/348 (21%), Positives = 149/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 499 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 555
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 556 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 611
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 612 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 671
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 672 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 730
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M+++ RL E + D Q + ++ LE +
Sbjct: 731 --LAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLK 788
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQRRRRGETAARL 623
E + + +K R +L Q +K+ LE ++E +R + R+
Sbjct: 789 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERI 836
>BC101517-1|AAI01518.1| 637|Homo sapiens RAB11 family interacting
protein 4 (class II) protein.
Length = 637
Score = 57.6 bits (133), Expect = 1e-07
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 315 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 372
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 373 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEE 432
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 433 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 488
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + E R + ++ + FN + +E +H+++
Sbjct: 489 FQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVK 547
>BC093914-1|AAH93914.1| 637|Homo sapiens RAB11 family interacting
protein 4 (class II) protein.
Length = 637
Score = 57.6 bits (133), Expect = 1e-07
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 315 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 372
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 373 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEE 432
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 433 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 488
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + E R + ++ + FN + +E +H+++
Sbjct: 489 FQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVK 547
>AY169244-1|AAO21970.1| 637|Homo sapiens rab11-family interacting
protein 4 protein.
Length = 637
Score = 57.6 bits (133), Expect = 1e-07
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 315 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 372
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 373 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEE 432
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 433 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 488
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + E R + ++ + FN + +E +H+++
Sbjct: 489 FQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVK 547
>AJ314646-1|CAC44535.1| 609|Homo sapiens hypothetical protein
protein.
Length = 609
Score = 57.6 bits (133), Expect = 1e-07
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 287 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 344
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 345 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEE 404
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 405 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 460
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + E R + ++ + FN + +E +H+++
Sbjct: 461 FQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVK 519
>AB058724-1|BAB47450.1| 609|Homo sapiens KIAA1821 protein protein.
Length = 609
Score = 57.6 bits (133), Expect = 1e-07
Identities = 57/239 (23%), Positives = 114/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 287 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 344
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 345 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKATEVELLNARVQQLEEE 404
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 405 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 460
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + E R + ++ + FN + +E +H+++
Sbjct: 461 FQKEREATQELIEDLRKELEHLQMYKLDCERPGRGRSASSGLGEFNARAREVELEHEVK 519
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 57.2 bits (132), Expect = 2e-07
Identities = 69/325 (21%), Positives = 151/325 (46%), Gaps = 33/325 (10%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMICEVENFRVVADDAQKKTSHFESE 351
A+D +I KL E S E+ H + L + V + + + +K+ S E
Sbjct: 304 ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+++ + A D K K LQ ++ E ++++ ++ L + ++EI +LK N
Sbjct: 364 MHRRFENAPD-SAKTKALQ----TVIEMKDSKISSMERGLRDLEEEIQMLKSNGALS--- 415
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
++ + +K +E KF K+ + +L + + S + + LK K
Sbjct: 416 TEEREEEMKQMEVYRSHSKFM----KNKVEQLKEELSSKEAQW-------EELKKKAAGL 464
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK----QLE- 526
++ ++Q+L K + + K + L N+ +QH+E+ K L Q+ Q E
Sbjct: 465 QAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEV 524
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEEQHKLEINVLEEK-- 583
DA+ +L+E + L++ +++++ A K + + K +L ++E+ ++NVL++K
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER---KVNVLQKKIE 581
Query: 584 -QREEIKLYRLQLAQAAEKLGLLES 607
+E+++ Q++ E++ L++
Sbjct: 582 NLQEQLRDKEKQMSSLKERVKSLQA 606
Score = 49.6 bits (113), Expect = 3e-05
Identities = 96/434 (22%), Positives = 185/434 (42%), Gaps = 39/434 (8%)
Query: 190 SYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRG 249
S A S +E + EM+ R KF++NK ++ + +L S W + ++ G
Sbjct: 410 SNGALSTEERE-EEMKQMEVYRSHSKFMKNK-VEQLKEELSSKEAQWEELKKKAAGL--- 464
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRL 309
+ +I ++++E L R+ E + + ++ K++ +K + A + L
Sbjct: 465 -QAEIGQVKQE-LSRKDTELLALQTKLETLTNQFSDS-KQHIEVLKESLTAKEQRAAI-L 520
Query: 310 TNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQL 369
+D R EK + + + D A++K + E++ D+ + K L
Sbjct: 521 QTEVDALRLRLE---EKETMLNKKTKQIQDMAEEKGTQ-AGEIHDLKDMLDVKERKVNVL 576
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EK 428
Q + ++L+EQL +K+K++ LKE ++ + LEEAL EK
Sbjct: 577 QKKIENLQEQLR-----------DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 429 EKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQ 486
E+ T + E R + E + ++DL LK KV+ + + E L + +
Sbjct: 626 ER-----TIERLKEQRDRDEREKQEE-IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLK 679
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LKCHYQ-KQLEDAVLAKLQEFQEQLDRAE 544
S + D+ +KTL LE +K E LK Q K+ +A L + + E DR +
Sbjct: 680 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAAL-EARASPEMSDRIQ 738
Query: 545 REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
R K+ + ++ R+ E K N +K ++ +L R Q+ +K+
Sbjct: 739 HLEREITRYKDES--SKAQAEVDRLLEILKEVENEKNDKDKKIAELER-QVKDQNKKVAN 795
Query: 605 LESKVECQRRRRGE 618
L+ K + ++++ +
Sbjct: 796 LKHKEQVEKKKSAQ 809
Score = 40.7 bits (91), Expect = 0.016
Identities = 66/325 (20%), Positives = 138/325 (42%), Gaps = 16/325 (4%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+A++ L+E L +S +D K LE + E + + ++Q K +H E
Sbjct: 671 KEASLLDLKEHASSLASS-GLKKDSRLKTLE-IALEQKKEECLKMESQLKKAH---EAAL 725
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-VMRLNK 413
+ + D+ + L+ E +++ + V+ +L KE++ K + D + L +
Sbjct: 726 EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEIL-KEVENEKNDKDKKIAELER 784
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------ETLLLTQER-DLLKS 466
Q+ D K + KE+ + + E +R ++ND ++L +R + L+
Sbjct: 785 QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E A E L ++++ + K+ + L ++ ++Q LE K +L Q E
Sbjct: 845 ALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAE 904
Query: 527 -DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+ L L+ + + EM+ +A L + D+ N +L + K + +R
Sbjct: 905 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDA-NIALLELSSSKKKTQEEVAALKR 963
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
E+ +L + Q ++ L+ E
Sbjct: 964 EKDRLVQQLKQQTQNRMKLMADNYE 988
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 57.2 bits (132), Expect = 2e-07
Identities = 69/325 (21%), Positives = 151/325 (46%), Gaps = 33/325 (10%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMICEVENFRVVADDAQKKTSHFESE 351
A+D +I KL E S E+ H + L + V + + + +K+ S E
Sbjct: 304 ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+++ + A D K K LQ ++ E ++++ ++ L + ++EI +LK N
Sbjct: 364 MHRRFENAPD-SAKTKALQ----TVIEMKDSKISSMERGLRDLEEEIQMLKSNGALS--- 415
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
++ + +K +E KF K+ + +L + + S + + LK K
Sbjct: 416 TEEREEEMKQMEVYRSHSKFM----KNKVEQLKEELSSKEAQW-------EELKKKAAGL 464
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK----QLE- 526
++ ++Q+L K + + K + L N+ +QH+E+ K L Q+ Q E
Sbjct: 465 QAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEV 524
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEEQHKLEINVLEEK-- 583
DA+ +L+E + L++ +++++ A K + + K +L ++E+ ++NVL++K
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER---KVNVLQKKIE 581
Query: 584 -QREEIKLYRLQLAQAAEKLGLLES 607
+E+++ Q++ E++ L++
Sbjct: 582 NLQEQLRDKEKQMSSLKERVKSLQA 606
Score = 49.6 bits (113), Expect = 3e-05
Identities = 96/434 (22%), Positives = 185/434 (42%), Gaps = 39/434 (8%)
Query: 190 SYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRG 249
S A S +E + EM+ R KF++NK ++ + +L S W + ++ G
Sbjct: 410 SNGALSTEERE-EEMKQMEVYRSHSKFMKNK-VEQLKEELSSKEAQWEELKKKAAGL--- 464
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRL 309
+ +I ++++E L R+ E + + ++ K++ +K + A + L
Sbjct: 465 -QAEIGQVKQE-LSRKDTELLALQTKLETLTNQFSDS-KQHIEVLKESLTAKEQRAAI-L 520
Query: 310 TNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQL 369
+D R EK + + + D A++K + E++ D+ + K L
Sbjct: 521 QTEVDALRLRLE---EKETMLNKKTKQIQDMAEEKGTQ-AGEIHDLKDMLDVKERKVNVL 576
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EK 428
Q + ++L+EQL +K+K++ LKE ++ + LEEAL EK
Sbjct: 577 QKKIENLQEQLR-----------DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 429 EKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQ 486
E+ T + E R + E + ++DL LK KV+ + + E L + +
Sbjct: 626 ER-----TIERLKEQRDRDEREKQEE-IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLK 679
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LKCHYQ-KQLEDAVLAKLQEFQEQLDRAE 544
S + D+ +KTL LE +K E LK Q K+ +A L + + E DR +
Sbjct: 680 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAAL-EARASPEMSDRIQ 738
Query: 545 REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
R K+ + ++ R+ E K N +K ++ +L R Q+ +K+
Sbjct: 739 HLEREITRYKDES--SKAQAEVDRLLEILKEVENEKNDKDKKIAELER-QVKDQNKKVAN 795
Query: 605 LESKVECQRRRRGE 618
L+ K + ++++ +
Sbjct: 796 LKHKEQVEKKKSAQ 809
Score = 40.7 bits (91), Expect = 0.016
Identities = 66/325 (20%), Positives = 138/325 (42%), Gaps = 16/325 (4%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+A++ L+E L +S +D K LE + E + + ++Q K +H E
Sbjct: 671 KEASLLDLKEHASSLASS-GLKKDSRLKTLE-IALEQKKEECLKMESQLKKAH---EAAL 725
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-VMRLNK 413
+ + D+ + L+ E +++ + V+ +L KE++ K + D + L +
Sbjct: 726 EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEIL-KEVENEKNDKDKKIAELER 784
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------ETLLLTQER-DLLKS 466
Q+ D K + KE+ + + E +R ++ND ++L +R + L+
Sbjct: 785 QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E A E L ++++ + K+ + L ++ ++Q LE K +L Q E
Sbjct: 845 ALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAE 904
Query: 527 -DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+ L L+ + + EM+ +A L + D+ N +L + K + +R
Sbjct: 905 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDA-NIALLELSSSKKKTQEEVAALKR 963
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
E+ +L + Q ++ L+ E
Sbjct: 964 EKDRLVQQLKQQTQNRMKLMADNYE 988
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 57.2 bits (132), Expect = 2e-07
Identities = 67/331 (20%), Positives = 152/331 (45%), Gaps = 30/331 (9%)
Query: 310 TNSLDRAEDRHRKALEKMI--CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
T L + +++ +EK+ CE E ++ D +H E KTL+ Q + +
Sbjct: 291 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELE 350
Query: 368 QLQNE-------KKSLEEQLNTELDNVNVMLSNKDKEID------------VLKENYDTV 408
L +E + LEE+L+ D + M + ++D ++KE+ ++
Sbjct: 351 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 410
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
R K L D + L E L KE+ H ++++ L I+ E + + D+ +S
Sbjct: 411 QRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 469
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ + E+QL + Q + ++ + L +V + + EL H + Q++D
Sbjct: 470 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH-KIQVQD 528
Query: 528 AVLAKLQEFQEQLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++ +L++ ++++ + + +++L++ N KQIL +E+++ I + E Q+
Sbjct: 529 -LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQIL-VEKENM--ILQMREGQK 584
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+EI++ +L+ + + +L + E + +++
Sbjct: 585 KEIEILTQKLSAKEDSIHILNEEYETKFKKK 615
Score = 48.4 bits (110), Expect = 8e-05
Identities = 69/274 (25%), Positives = 116/274 (42%), Gaps = 26/274 (9%)
Query: 410 RLNKQLTDCVKNLEEALEKEK-FAHDSTKSNITEL----NKRIQSVNDETL-LLTQERDL 463
+L QL D KNL E LE++K TK + E + I + + TQ +L
Sbjct: 6 KLITQLRDA-KNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 64
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT-----------LRQHLEL 512
+ K ER+ +E+ L Q K +D ++KT L+Q L
Sbjct: 65 REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR 124
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQE-QLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
K E+ +K E+ + AKLQ+ E +L R E+E+ + +E + K L +
Sbjct: 125 VKQEVVDVMKKSSEEQI-AKLQKLHEKELARKEQELTKKLQTREREFQEQM-KVALEKSQ 182
Query: 572 QHKLEINVLEEKQR----EEIKLYRLQ-LAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
L+I+ +E+Q EE++L + L ++ KL L+ + E R R E + L +
Sbjct: 183 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 242
Query: 627 LQAHWRHALRILAAPHHDLGTHSHSTPSNVSEHK 660
LQ + + + + H+ V +HK
Sbjct: 243 LQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHK 276
Score = 35.5 bits (78), Expect = 0.60
Identities = 35/201 (17%), Positives = 87/201 (43%), Gaps = 11/201 (5%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+ + R + A ++ + L L D+ H+ +E + +++ A K F
Sbjct: 408 VSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVF 466
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+S T + Y+++ QLQ + LE + ++L+ + E++ K++ T
Sbjct: 467 QSYQSATHEQTKAYEEQLAQLQQKLLDLETE--------RILLTKQVAEVEAQKKDVCTE 518
Query: 409 MRLNK-QLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS 466
+ +K Q+ D ++ LE + E E+ T+ ++L + +L ++ +++
Sbjct: 519 LDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQ 578
Query: 467 KVNEERSRCAVIEQQLCEKQN 487
++ ++ Q+L K++
Sbjct: 579 MREGQKKEIEILTQKLSAKED 599
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 57.2 bits (132), Expect = 2e-07
Identities = 74/331 (22%), Positives = 147/331 (44%), Gaps = 20/331 (6%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
++ ++E + R L R+E R ++ EKM+ ++ + Q +T + + L
Sbjct: 853 MATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGL 912
Query: 359 AHD---YQDKCKQLQNEKKSLEEQLNTEL----DNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ K K+L E+ EE++N+EL N+ S+ ++ID L+ V +
Sbjct: 913 IKSKILLEAKVKEL-TERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKE 971
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ VKNL E E A + S +T+ K +Q + +TL + + + KVN
Sbjct: 972 KHATENKVKNLSE----EMTALEENISKLTKEKKSLQEAHQQTL---DDLQVEEDKVNGL 1024
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLEDAVL 530
A +EQQ + + + K L+ + L L++ Q++ + +KQ + L
Sbjct: 1025 IKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKL 1084
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE--INVLEEKQREEI 588
K +EF+ +A + E L+ + +I +EE+ + E + EKQR ++
Sbjct: 1085 KK-KEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDL 1143
Query: 589 KLYRLQLAQAAEKL-GLLESKVECQRRRRGE 618
++++ E+ G +++E ++R E
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAE 1174
Score = 54.8 bits (126), Expect = 9e-07
Identities = 70/303 (23%), Positives = 147/303 (48%), Gaps = 30/303 (9%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + +++ + + AQK++ +EL+K + + D+ + L+
Sbjct: 1445 TLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRR 1504
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ ++ K L+E T + ++ +D L+ ALE+ +
Sbjct: 1505 ENKNLQE----EISDLTEQIAETGKN---LQEAEKTKKLVEQEKSD----LQVALEEVEG 1553
Query: 432 AHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKSKVNEERSRCA---VIEQQLCEKQ 486
+ + +S I + + V E ++ ++ ++ + K N +R+ A V++ ++ +
Sbjct: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEI-RSR 1612
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
N + KK + NE++ H Q E + H + V +L++ Q LD A R
Sbjct: 1613 NDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLR-----TVQGQLKDSQLHLDDALRS 1667
Query: 547 MENDARLKEN-NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLL 605
E+ LKE IV+ N L +EE ++++ LE+ +R +L +L A++++ LL
Sbjct: 1668 NED---LKEQLAIVERRNG--LLLEELEEMKV-ALEQTERTR-RLSEQELLDASDRVQLL 1720
Query: 606 ESK 608
S+
Sbjct: 1721 HSQ 1723
Score = 52.8 bits (121), Expect = 4e-06
Identities = 64/306 (20%), Positives = 143/306 (46%), Gaps = 27/306 (8%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL--EEQ 379
+A ++M E+F ++ + + + K + L + D Q+Q+E ++L E+
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSN 439
L ++L K KE L E + +N +L +NLE+ K D +
Sbjct: 908 RCEGLIKSKILLEAKVKE---LTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELT 964
Query: 440 ITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL 499
+T++ K + ++ L++E L+ + S+ ++ L E Q + L+ +
Sbjct: 965 LTKVEKEKHATENKVKNLSEEMTALEENI----SKLTKEKKSLQEAHQQTLDDLQVEEDK 1020
Query: 500 DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
N + + LE Q ++L+ +++ ++ + L+RA+R++E D ++ + +I+
Sbjct: 1021 VNGLIKINAKLEQQTDDLEGSLEQE---------KKLRADLERAKRKLEGDLKMSQESIM 1071
Query: 560 DSFNKQILRIEEQHK---LEINVLEEKQREEIKLYRLQLAQAAEKLGL----LESKVECQ 612
D N++ +IEE+ K E++ L+ + +E +++ LQ + ++L LE ++E +
Sbjct: 1072 DLENEK-QQIEEKLKKKEFELSQLQARIDDE-QVHSLQFQKKIKELQARIEELEEEIEAE 1129
Query: 613 RRRRGE 618
R +
Sbjct: 1130 HTLRAK 1135
Score = 49.6 bits (113), Expect = 3e-05
Identities = 99/474 (20%), Positives = 206/474 (43%), Gaps = 48/474 (10%)
Query: 171 RVLEQYKASYSKNKPGATDSYSASSNQELKLPEMR-PFGENRESLKFI--QNKYIDTIDS 227
+VL ++K +++ + S + +L +MR + E + L+ + +NK + S
Sbjct: 1455 KVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEIS 1514
Query: 228 DLLSLSELWG---DKAERTTGYNRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXX 283
DL G +AE+T +K D+ + LEE EH E+ I
Sbjct: 1515 DLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILR---------- 1564
Query: 284 XXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMI-CEVENFRVVADDAQ 342
V +++ + K K+ E + L R R +AL+ ++ E+ + +DA
Sbjct: 1565 ---VQLELSQVKSELDRKVIEKDEEI-EQLKRNSQRAAEALQSVLDAEIRS----RNDAL 1616
Query: 343 KKTSHFESELYKT-LDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDV 400
+ E +L + + L H + + Q ++++ QL +++L + + SN+D
Sbjct: 1617 RLKKKMEGDLNEMEIQLGHSNRQMA-ETQRHLRTVQGQLKDSQLHLDDALRSNED----- 1670
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
LKE V R N L + ++ ++ ALE+ + ++ + + + R+Q ++ + L
Sbjct: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ---HLELQKNEL 517
+ L++ + + ++ Q+ + + + + + E+K + HLE K L
Sbjct: 1731 KKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1790
Query: 518 K---CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
+ Q +L++A L+ ++Q+ +++EN R EN + + ++ HK
Sbjct: 1791 EQTVKDLQHRLDEAEQLALKGGKKQI----QKLENRVRELENELDVEQKRGAEALKGAHK 1846
Query: 575 LEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAAL 627
E V E Q EE + L+L +K L++KV+ +R+ E + + L
Sbjct: 1847 YERKVKEMTYQAEEDRKNILRLQDLVDK---LQAKVKSYKRQAEEAEEQANTQL 1897
Score = 46.0 bits (104), Expect = 4e-04
Identities = 62/338 (18%), Positives = 142/338 (42%), Gaps = 20/338 (5%)
Query: 305 AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
A + + + + R+ LE+ + E A +KK + +EL + +D +
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHE---ATAATLRKKQADSVAELGEQIDNLQRVKQ 1219
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K ++ ++E K + + + ++ ++ SN ++ +++ + + ++Q T + +L
Sbjct: 1220 KLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNM 1279
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
+ + + + E I + LTQ+ + LK ++ EE + L
Sbjct: 1280 QKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQS 1339
Query: 485 KQNQCSEVLKKCDFLDNEVKT-LRQHLELQKNEL---KCHYQ-------KQLEDAVLAKL 533
++ C ++L++ + E K L++ L +E+ K Y+ ++LE+A
Sbjct: 1340 SRHDC-DLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLA 1398
Query: 534 QEFQEQLDRAEREMENDARL-KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
Q QE ++ E A L K + + ++R E+ L++KQR K+
Sbjct: 1399 QRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKV-- 1456
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
LA+ +KL ++++E ++ + L A+
Sbjct: 1457 --LAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAY 1492
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 57.2 bits (132), Expect = 2e-07
Identities = 69/325 (21%), Positives = 151/325 (46%), Gaps = 33/325 (10%)
Query: 294 AKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMICEVENFRVVADDAQKKTSHFESE 351
A+D +I KL E S E+ H + L + V + + + +K+ S E
Sbjct: 304 ARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREE 363
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+++ + A D K K LQ ++ E ++++ ++ L + ++EI +LK N
Sbjct: 364 MHRRFENAPD-SAKTKALQ----TVIEMKDSKISSMERGLRDLEEEIQMLKSNGALS--- 415
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
++ + +K +E KF K+ + +L + + S + + LK K
Sbjct: 416 TEEREEEMKQMEVYRSHSKFM----KNKVEQLKEELSSKEAQW-------EELKKKAAGL 464
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK----QLE- 526
++ ++Q+L K + + K + L N+ +QH+E+ K L Q+ Q E
Sbjct: 465 QAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEV 524
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEEQHKLEINVLEEK-- 583
DA+ +L+E + L++ +++++ A K + + K +L ++E+ ++NVL++K
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKER---KVNVLQKKIE 581
Query: 584 -QREEIKLYRLQLAQAAEKLGLLES 607
+E+++ Q++ E++ L++
Sbjct: 582 NLQEQLRDKEKQMSSLKERVKSLQA 606
Score = 49.6 bits (113), Expect = 3e-05
Identities = 96/434 (22%), Positives = 185/434 (42%), Gaps = 39/434 (8%)
Query: 190 SYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRG 249
S A S +E + EM+ R KF++NK ++ + +L S W + ++ G
Sbjct: 410 SNGALSTEERE-EEMKQMEVYRSHSKFMKNK-VEQLKEELSSKEAQWEELKKKAAGL--- 464
Query: 250 DKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRL 309
+ +I ++++E L R+ E + + ++ K++ +K + A + L
Sbjct: 465 -QAEIGQVKQE-LSRKDTELLALQTKLETLTNQFSDS-KQHIEVLKESLTAKEQRAAI-L 520
Query: 310 TNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQL 369
+D R EK + + + D A++K + E++ D+ + K L
Sbjct: 521 QTEVDALRLRLE---EKETMLNKKTKQIQDMAEEKGTQ-AGEIHDLKDMLDVKERKVNVL 576
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EK 428
Q + ++L+EQL +K+K++ LKE ++ + LEEAL EK
Sbjct: 577 QKKIENLQEQLR-----------DKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 625
Query: 429 EKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQ 486
E+ T + E R + E + ++DL LK KV+ + + E L + +
Sbjct: 626 ER-----TIERLKEQRDRDEREKQEE-IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLK 679
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LKCHYQ-KQLEDAVLAKLQEFQEQLDRAE 544
S + D+ +KTL LE +K E LK Q K+ +A L + + E DR +
Sbjct: 680 EHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAAL-EARASPEMSDRIQ 738
Query: 545 REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
R K+ + ++ R+ E K N +K ++ +L R Q+ +K+
Sbjct: 739 HLEREITRYKDES--SKAQAEVDRLLEILKEVENEKNDKDKKIAELER-QVKDQNKKVAN 795
Query: 605 LESKVECQRRRRGE 618
L+ K + ++++ +
Sbjct: 796 LKHKEQVEKKKSAQ 809
Score = 40.7 bits (91), Expect = 0.016
Identities = 66/325 (20%), Positives = 138/325 (42%), Gaps = 16/325 (4%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K+A++ L+E L +S +D K LE + E + + ++Q K +H E
Sbjct: 671 KEASLLDLKEHASSLASS-GLKKDSRLKTLE-IALEQKKEECLKMESQLKKAH---EAAL 725
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-VMRLNK 413
+ + D+ + L+ E +++ + V+ +L KE++ K + D + L +
Sbjct: 726 EARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEIL-KEVENEKNDKDKKIAELER 784
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------ETLLLTQER-DLLKS 466
Q+ D K + KE+ + + E +R ++ND ++L +R + L+
Sbjct: 785 QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E A E L ++++ + K+ + L ++ ++Q LE K +L Q E
Sbjct: 845 ALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAE 904
Query: 527 -DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+ L L+ + + EM+ +A L + D+ N +L + K + +R
Sbjct: 905 KETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDA-NIALLELSSSKKKTQEEVAALKR 963
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVE 610
E+ +L + Q ++ L+ E
Sbjct: 964 EKDRLVQQLKQQTQNRMKLMADNYE 988
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 56.8 bits (131), Expect = 2e-07
Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 35/457 (7%)
Query: 187 ATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGY 246
AT+ S N+ LK EN + + ++K I S ++ EL + G
Sbjct: 548 ATEKLS-KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGLGA 605
Query: 247 NRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREA 305
+ ++ ++E+ RL +H I A M+ RAK + K +E
Sbjct: 606 ETAEFAELKTQIEKMRLDYQH---EIENLQNQQNSERAAHAKEMEALRAKLMKVIKEKEN 662
Query: 306 WLRLTNS-LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
L S LD+AED+H +E + +++ + + + + +E K +D
Sbjct: 663 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC-NEQTKVID------- 714
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
++ K+ EE+L +LD + S E+ L++ + + K L + KN E
Sbjct: 715 ---NFTSQPKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHL-EIEKNAES 769
Query: 425 ALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ + +T L + + V+ L +E +LK K E +++ +
Sbjct: 770 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 829
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL--------ELQKNELKCHYQKQLEDAVLAKLQE 535
E N+ + ++ + L ++++ LR++L E + E + K+ + +A++ +
Sbjct: 830 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 889
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV------LEEKQREEIK 589
+M ++ RLKE ++ + K E L+ ++ E+ Q+E K
Sbjct: 890 MSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAK 949
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ + + KL LE K+E + E AR A
Sbjct: 950 KHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 986
Score = 46.0 bits (104), Expect = 4e-04
Identities = 64/370 (17%), Positives = 166/370 (44%), Gaps = 35/370 (9%)
Query: 287 VAMKVDRAKDAAISK-LREAWLRLTNSLDRAED--RHRKALEKMICEVENFRVVADDAQK 343
+ + +K ++I++ L+ L+LTN + + + ++ LEK E++ + +A +
Sbjct: 763 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK---ELQILKEKFAEASE 819
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
+ + + +T++ H +++ L ++ + L E L +++ +++++ KE
Sbjct: 820 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL-ADMEAKFREKDEREEQLIKAKE 878
Query: 404 NYDT----VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI----QSVNDETL 455
+ +M+++ + + + + L ++ + + +T+ N+ +S+ D T+
Sbjct: 879 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 938
Query: 456 LLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL- 510
Q + K EE+ + + +E+++ NQC E+ + + +E KT + +
Sbjct: 939 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 998
Query: 511 -ELQK----NELKCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNIVDSFNK 564
LQK E K ++ +L +L+E ++Q D+A+ + DA + +
Sbjct: 999 QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTE 1058
Query: 565 QILRIEEQHKL------EINVLEE---KQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+ +E+ + E++ L+E K EE+ + L +K+ ++E ++
Sbjct: 1059 TLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1118
Query: 616 RGETAARLHA 625
+ + +L A
Sbjct: 1119 AAQKSQQLSA 1128
Score = 40.7 bits (91), Expect = 0.016
Identities = 65/325 (20%), Positives = 144/325 (44%), Gaps = 35/325 (10%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVAD------- 339
+ +RA +K E L +L ED+ + A E+ ++ E+E R AD
Sbjct: 982 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1041
Query: 340 --DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNT--ELDNVNVMLSNK 394
DA + E +TL D + +LQNE +L+E L EL+ +L+ +
Sbjct: 1042 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1101
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD--STKSNIT---ELNKRIQS 449
+++++ ++ +T+ + Q + + L+E E K A + ++ +T +L +
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSALQE--ENVKLAEELGRSRDEVTSHQKLEEERSV 1159
Query: 450 VNDETLLLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNE--- 502
+N++ L + + +EE++ ++ L EK + ++ + L E
Sbjct: 1160 LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENAS 1219
Query: 503 VKTLRQHLE-LQKNELKCHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
K+L ++ L+ +++K + K LE + ++ + + + D R +E+ I D
Sbjct: 1220 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI-D 1278
Query: 561 SFNKQILRIEEQH---KLEINVLEE 582
N I+ ++ ++ K+++ ++ E
Sbjct: 1279 FLNSVIVDLQRKNQDLKMKVEMMSE 1303
Score = 39.9 bits (89), Expect = 0.028
Identities = 65/300 (21%), Positives = 138/300 (46%), Gaps = 37/300 (12%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES---ELYKTLDL-AHDYQDKCKQ 368
L++ E+ RK +E + VE + D + T +S EL K L L + + ++
Sbjct: 428 LNQLEEEKRK-VEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRR 486
Query: 369 LQNEKK--------SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
L++ K SL +++++ + + V ++ +EI LKE++ +++ +K
Sbjct: 487 LESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE---IK 543
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
L A EK ++S KS + NK N + + L + + L++ + + A+ E
Sbjct: 544 ALYTATEKLSKENESLKSKLEHANKE----NSDVIALWKSK--LETAIASHQQ--AMEEL 595
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK-LQEFQEQ 539
++ + +E +F + + + + L+ Q Q+ E A AK ++ + +
Sbjct: 596 KVSFSKGLGAET---AEFAELKTQIEKMRLDYQHEIENLQNQQNSERAAHAKEMEALRAK 652
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI-NVLEEKQREEIKLYRLQLAQA 598
L + +E EN +++ ++ + E+QH +E+ + L + Q EIK+ L++ QA
Sbjct: 653 LMKVIKEKENS--------LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQA 704
Score = 38.3 bits (85), Expect = 0.085
Identities = 62/319 (19%), Positives = 129/319 (40%), Gaps = 19/319 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
A+ V R+ ++KL + + N L ++ R+ L M + + K
Sbjct: 821 AVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 879
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEI-DVLKE 403
E+++ + + ++ D + ++ +E + E E+L +L N S K I D+ +
Sbjct: 880 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET------LLL 457
+ K+ + K LE L + +++ + EL R + ET +L
Sbjct: 940 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 999
Query: 458 TQERDLL--KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++ LL + K+ R + + Q+L E + Q + K ++ ++ + Q + +K
Sbjct: 1000 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKA-KAAQTAEDAMQIMEQ-MTKEKT 1057
Query: 516 ELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEE 571
E + KQ + +L +E + E+ L EN ++ F K+I +++
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 572 QHKLEINVLEEKQREEIKL 590
+ L Q E +KL
Sbjct: 1118 AAAQKSQQLSALQEENVKL 1136
Score = 35.5 bits (78), Expect = 0.60
Identities = 45/226 (19%), Positives = 101/226 (44%), Gaps = 12/226 (5%)
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S T L + ++ L ERDL +++V + S IEQ+L ++ + + + +
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN 557
++++T+ + + +K EL +++ + + +E + + + E+ A + E +
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEV---ATVSEKS 464
Query: 558 IVDSFNKQI-LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR--R 614
+ K + LR++E +L + K ++ + L L Q ++ L+ K+E R
Sbjct: 465 RIMELEKDLALRVQEVAELRRRLESNKPAGDVDM-SLSLLQ---EISSLQEKLEVTRTDH 520
Query: 615 RRGETAARLH-AALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEH 659
+R T+ + H A + + ++ L L + S S + EH
Sbjct: 521 QREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL-EH 565
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 56.8 bits (131), Expect = 2e-07
Identities = 66/327 (20%), Positives = 147/327 (44%), Gaps = 19/327 (5%)
Query: 303 REAWLRLTNSLDRAEDRHR-KALEKMICEVENFRVVADDA-QKKTSHFESELYKTLDLAH 360
R+ L + N + E+R R +A + + N +V + Q++ E EL K L+
Sbjct: 628 RQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELF 687
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNK 413
+ + +Q Q E + L++QL+ D ++ ++D+E L K++ ++ +
Sbjct: 688 QVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKE 747
Query: 414 QLTDCVKN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLK 465
D ++ L+ AL++E +HD + E + +Q++ + T+ ++L
Sbjct: 748 GREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLA 807
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCHYQKQ 524
S+ N A E ++ Q + ++ + + L+ V L++ +E L+ +E K +
Sbjct: 808 SRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 525 LEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEE-K 583
+ + +L+E + E+E + R EN + + +EQ +L + EE +
Sbjct: 868 KYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESE 927
Query: 584 QREEIKLYRLQLAQAAEKLGLLESKVE 610
Q+E+++ + ++ LG K++
Sbjct: 928 QKEQLRRLKNEMENERWHLGKTIEKLQ 954
Score = 46.8 bits (106), Expect = 2e-04
Identities = 63/325 (19%), Positives = 144/325 (44%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 952 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 1011
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 1012 DGMRLMEEELRDYQRAQDEALTKRQLLEQ-----------TLKDLEYELEAKSHLKDDRS 1060
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ V LE LE+E ++N L++RI +S+
Sbjct: 1061 RLVKQMEAKVSQLEMELEEE-------RNNSDLLSERIS----------------RSREQ 1097
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
E+ R +++++ + +C ++ + + ++K+ HLE K Q+E
Sbjct: 1098 MEQLRNGLLQERAARQDLECGKI--SLERQNKDLKSRIIHLEGSYRSSKEGLVVQME--- 1152
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 1153 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 1209
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 44.0 bits (99), Expect = 0.002
Identities = 75/348 (21%), Positives = 147/348 (42%), Gaps = 27/348 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 754 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 810
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 811 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 866
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L ++ TQE+ L K+ EE
Sbjct: 867 KKYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEES 926
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 927 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 985
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M++ RL E + D Q + ++ LE +
Sbjct: 986 --LAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLK 1043
Query: 580 ---LEEKQREEIKLYRLQLAQAAE-KLGLLESKVECQRRRRGETAARL 623
E + + +K R +L + E K+ LE ++E +R + R+
Sbjct: 1044 DLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERI 1091
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 56.4 bits (130), Expect = 3e-07
Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 35/457 (7%)
Query: 187 ATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGY 246
AT+ S N+ LK EN + + ++K I S ++ EL + G
Sbjct: 583 ATEKLS-KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGLGT 640
Query: 247 NRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREA 305
+ ++ ++E+ RL +H I A M+ RAK + K +E
Sbjct: 641 ETAEFAELKTQIEKMRLDYQH---EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKEN 697
Query: 306 WLRLTNS-LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
L S LD+AED+H +E + +++ + + + + +E K +D
Sbjct: 698 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC-NEQTKVID------- 749
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
++ K+ EE+L +LD + S E+ L++ + + K L + KN E
Sbjct: 750 ---NFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHL-EIEKNAES 804
Query: 425 ALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ + +T L + + V+ L +E +LK K E +++ +
Sbjct: 805 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 864
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL--------ELQKNELKCHYQKQLEDAVLAKLQE 535
E N+ + ++ + L ++++ LR++L E + E + K+ + +A++ +
Sbjct: 865 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 924
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV------LEEKQREEIK 589
+M ++ RLKE ++ + K E L+ ++ E+ Q+E K
Sbjct: 925 MSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAK 984
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ + + KL LE K+E + E AR A
Sbjct: 985 KHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 1021
Score = 46.0 bits (104), Expect = 4e-04
Identities = 64/370 (17%), Positives = 166/370 (44%), Gaps = 35/370 (9%)
Query: 287 VAMKVDRAKDAAISK-LREAWLRLTNSLDRAED--RHRKALEKMICEVENFRVVADDAQK 343
+ + +K ++I++ L+ L+LTN + + + ++ LEK E++ + +A +
Sbjct: 798 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK---ELQILKEKFAEASE 854
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
+ + + +T++ H +++ L ++ + L E L +++ +++++ KE
Sbjct: 855 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL-ADMEAKFREKDEREEQLIKAKE 913
Query: 404 NYDT----VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI----QSVNDETL 455
+ +M+++ + + + + L ++ + + +T+ N+ +S+ D T+
Sbjct: 914 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 973
Query: 456 LLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL- 510
Q + K EE+ + + +E+++ NQC E+ + + +E KT + +
Sbjct: 974 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 1033
Query: 511 -ELQK----NELKCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNIVDSFNK 564
LQK E K ++ +L +L+E ++Q D+A+ + DA + +
Sbjct: 1034 QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTE 1093
Query: 565 QILRIEEQHKL------EINVLEE---KQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+ +E+ + E++ L+E K EE+ + L +K+ ++E ++
Sbjct: 1094 TLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1153
Query: 616 RGETAARLHA 625
+ + +L A
Sbjct: 1154 AAQKSQQLSA 1163
Score = 40.7 bits (91), Expect = 0.016
Identities = 65/325 (20%), Positives = 144/325 (44%), Gaps = 35/325 (10%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVAD------- 339
+ +RA +K E L +L ED+ + A E+ ++ E+E R AD
Sbjct: 1017 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1076
Query: 340 --DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNT--ELDNVNVMLSNK 394
DA + E +TL D + +LQNE +L+E L EL+ +L+ +
Sbjct: 1077 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1136
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD--STKSNIT---ELNKRIQS 449
+++++ ++ +T+ + Q + + L+E E K A + ++ +T +L +
Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSALQE--ENVKLAEELGRSRDEVTSHQKLEEERSV 1194
Query: 450 VNDETLLLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNE--- 502
+N++ L + + +EE++ ++ L EK + ++ + L E
Sbjct: 1195 LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENAS 1254
Query: 503 VKTLRQHLE-LQKNELKCHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
K+L ++ L+ +++K + K LE + ++ + + + D R +E+ I D
Sbjct: 1255 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI-D 1313
Query: 561 SFNKQILRIEEQH---KLEINVLEE 582
N I+ ++ ++ K+++ ++ E
Sbjct: 1314 FLNSVIVDLQRKNQDLKMKVEMMSE 1338
Score = 38.7 bits (86), Expect = 0.065
Identities = 48/226 (21%), Positives = 107/226 (47%), Gaps = 24/226 (10%)
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
SL +++++ + + V ++ +EI LKE++ +++ +K L A EK ++
Sbjct: 536 SLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE---IKALYTATEKLSKENE 592
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
S KS + NK N + + L + + L++ + + A+ E ++ + +E
Sbjct: 593 SLKSKLEHANKE----NSDVIALWKSK--LETAIASHQQ--AMEELKVSFSKGLGTET-- 642
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK-LQEFQEQLDRAEREMENDARL 553
+F + + + + L+ Q Q+ E A AK ++ + +L + +E EN
Sbjct: 643 -AEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENS--- 698
Query: 554 KENNIVDSFNKQILRIEEQHKLEI-NVLEEKQREEIKLYRLQLAQA 598
+++ ++ + E+QH +E+ + L + Q EIK+ L++ QA
Sbjct: 699 -----LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQA 739
Score = 38.3 bits (85), Expect = 0.085
Identities = 62/319 (19%), Positives = 129/319 (40%), Gaps = 19/319 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
A+ V R+ ++KL + + N L ++ R+ L M + + K
Sbjct: 856 AVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 914
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEI-DVLKE 403
E+++ + + ++ D + ++ +E + E E+L +L N S K I D+ +
Sbjct: 915 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET------LLL 457
+ K+ + K LE L + +++ + EL R + ET +L
Sbjct: 975 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1034
Query: 458 TQERDLL--KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++ LL + K+ R + + Q+L E + Q + K ++ ++ + Q + +K
Sbjct: 1035 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKA-KAAQTAEDAMQIMEQ-MTKEKT 1092
Query: 516 ELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEE 571
E + KQ + +L +E + E+ L EN ++ F K+I +++
Sbjct: 1093 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1152
Query: 572 QHKLEINVLEEKQREEIKL 590
+ L Q E +KL
Sbjct: 1153 AAAQKSQQLSALQEENVKL 1171
Score = 31.9 bits (69), Expect = 7.4
Identities = 37/177 (20%), Positives = 78/177 (44%), Gaps = 7/177 (3%)
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S T L + ++ L ERDL +++V + S IEQ+L ++ + + + +
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME---NDARLK 554
++++T+ + + +K EL +++ + + +E + + + E + AR+K
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIK 467
Query: 555 --ENNIVDSFNKQILRIEEQHKLEINVLEEKQR--EEIKLYRLQLAQAAEKLGLLES 607
E +++ K E + + EK R E K L++ + AE LES
Sbjct: 468 ELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLES 524
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 56.4 bits (130), Expect = 3e-07
Identities = 66/290 (22%), Positives = 132/290 (45%), Gaps = 29/290 (10%)
Query: 308 RLTNSLDRAEDRH---RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
+L LD A++ + + ++ +I EVE+ + + ++ S ++++ L
Sbjct: 387 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLV----S 442
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K Q++ E + +EQ N EL N+ V L K I VL+ ++ + L KNLE
Sbjct: 443 KLSQVEGEHQLWKEQ-NLELRNLTVELEQK---IQVLQSKNASLQDTLEVLQSSYKNLEN 498
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LE K S + ++ + + E + Q+ L+ +++ E++R A Q L E
Sbjct: 499 ELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLE 558
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLDR 542
+ + LK+ ++E+K L C ++ Q+ E V ++ E+Q +L
Sbjct: 559 EIKSSKDQLKELTLENSELK----------KSLDCMHKDQVEKEGKVREEIAEYQLRLHE 608
Query: 543 AEREMEN---DARLKENNIVDSFNKQILRIEE---QHKLEINVLEEKQRE 586
AE++ + D + + ++ +++ EE KLEI++L+ + E
Sbjct: 609 AEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 658
Score = 44.8 bits (101), Expect = 0.001
Identities = 65/266 (24%), Positives = 114/266 (42%), Gaps = 27/266 (10%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNV 389
+E RV + +KK H +L K D +D +DK + L+ E + EE N EL V +
Sbjct: 24 IEKLRVRIEADEKKQLHIAEKL-KERDGENDSLKDKVENLERELQMSEE--NQEL--VIL 78
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
N E++ LK + + R K + L E + ++EL+K + S
Sbjct: 79 DAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSS 138
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC-------SEVLKKCD-FLD- 500
+ +E++ + ++ EE + Q ++ N+ E++K + LD
Sbjct: 139 FKSQ----LEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDP 194
Query: 501 --NEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
E LR +E + L+ +KQL VL +L+E + D + +EN R E
Sbjct: 195 PIEEEHQLRNSIEKLRARLEADEKKQL--CVLQQLKESEHHADLLKGRVENLERELE--- 249
Query: 559 VDSFNKQILRIE-EQHKLEINVLEEK 583
+ N++ +E E K E+ L+ K
Sbjct: 250 IARTNQEHAALEAENSKGEVETLKAK 275
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/330 (22%), Positives = 142/330 (43%), Gaps = 24/330 (7%)
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKT-LDLAHDYQD 364
LTN L + ++R + LE + EN + + K+ S E+ +T L +
Sbjct: 300 LTNELQKEQERISE-LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSMREWQ 358
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
C + + E+ L+++++ + + + + +D K NY + L V++ ++
Sbjct: 359 PCIMTKKPVSAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQ 418
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
LEK+ K+ I + + + ++ + E L K + E R+ +EQ++
Sbjct: 419 KLEKKDEEISRLKNQIQDQEQLVSKLSQ----VEGEHQLWKEQNLELRNLTVELEQKIQV 474
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE 544
Q++ + + + L + K L LEL K + +K + K+ + +L R
Sbjct: 475 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK------VNKMTAKETELQREM 528
Query: 545 REM-ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
EM + A L+E S K L E Q LE + Q +E+ L +L ++ + +
Sbjct: 529 HEMAQKTAELQEEL---SGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH 585
Query: 604 LLESKVECQRRRRGETA---ARLHAALQAH 630
+ +VE + + R E A RLH A + H
Sbjct: 586 --KDQVEKEGKVREEIAEYQLRLHEAEKKH 613
Score = 37.9 bits (84), Expect = 0.11
Identities = 45/179 (25%), Positives = 84/179 (46%), Gaps = 13/179 (7%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D KQ + E ++ E+L ++ + LS++ EID+LK + + LN L + LE
Sbjct: 619 DTNKQYEVEIQTYREKLTSKEE----CLSSQKLEIDLLKSSKE---ELNNSLKATTQILE 671
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E L+K K + + + + N+R Q + ++ + K + +E S+ +
Sbjct: 672 E-LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ---- 726
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLD 541
EKQ + + K D L E+K L++ LE + E + K + KL++ +E L+
Sbjct: 727 EKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLE 785
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker
protein-170 alpha-2 protein.
Length = 1392
Score = 56.4 bits (130), Expect = 3e-07
Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 35/457 (7%)
Query: 187 ATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGY 246
AT+ S N+ LK EN + + ++K I S ++ EL + G
Sbjct: 548 ATEKLS-KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGLGT 605
Query: 247 NRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREA 305
+ ++ ++E+ RL +H I A M+ RAK + K +E
Sbjct: 606 ETAEFAELKTQIEKMRLDYQH---EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKEN 662
Query: 306 WLRLTNS-LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
L S LD+AED+H +E + +++ + + + + +E K +D
Sbjct: 663 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC-NEQTKVID------- 714
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
++ K+ EE+L +LD + S E+ L++ + + K L + KN E
Sbjct: 715 ---NFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHL-EIEKNAES 769
Query: 425 ALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ + +T L + + V+ L +E +LK K E +++ +
Sbjct: 770 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 829
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL--------ELQKNELKCHYQKQLEDAVLAKLQE 535
E N+ + ++ + L ++++ LR++L E + E + K+ + +A++ +
Sbjct: 830 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 889
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV------LEEKQREEIK 589
+M ++ RLKE ++ + K E L+ ++ E+ Q+E K
Sbjct: 890 MSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAK 949
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ + + KL LE K+E + E AR A
Sbjct: 950 KHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 986
Score = 44.4 bits (100), Expect = 0.001
Identities = 63/370 (17%), Positives = 166/370 (44%), Gaps = 35/370 (9%)
Query: 287 VAMKVDRAKDAAISK-LREAWLRLTNSLDRAED--RHRKALEKMICEVENFRVVADDAQK 343
+ + +K ++I++ L+ L+LTN + + + ++ LEK E++ + +A +
Sbjct: 763 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK---ELQILKEKFAEASE 819
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
+ + + +T++ H +++ L ++ + L E L +++ +++++ KE
Sbjct: 820 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL-ADMEAKFREKDEREEQLIKAKE 878
Query: 404 NYDT----VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI----QSVNDETL 455
+ +M+++ + + + + L ++ + + +T+ N+ +S+ D T+
Sbjct: 879 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 938
Query: 456 LLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL- 510
Q + K EE+ + + +E+++ NQC E+ + + +E KT + +
Sbjct: 939 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 998
Query: 511 -ELQK----NELKCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNIVDSFNK 564
LQK E K ++ +L +L+E ++Q ++A+ + DA + +
Sbjct: 999 QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTE 1058
Query: 565 QILRIEEQHKL------EINVLEE---KQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+ +E+ + E++ L+E K EE+ + L +K+ ++E ++
Sbjct: 1059 TLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1118
Query: 616 RGETAARLHA 625
+ + +L A
Sbjct: 1119 AAQKSQQLSA 1128
Score = 39.9 bits (89), Expect = 0.028
Identities = 65/300 (21%), Positives = 138/300 (46%), Gaps = 37/300 (12%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFES---ELYKTLDL-AHDYQDKCKQ 368
L++ E+ RK +E + VE + D + T +S EL K L L + + ++
Sbjct: 428 LNQLEEEKRK-VEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRR 486
Query: 369 LQNEKK--------SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
L++ K SL +++++ + + V ++ +EI LKE++ +++ +K
Sbjct: 487 LESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE---IK 543
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
L A EK ++S KS + NK N + + L + + L++ + + A+ E
Sbjct: 544 ALYTATEKLSKENESLKSKLEHANKE----NSDVIALWKSK--LETAIASHQQ--AMEEL 595
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK-LQEFQEQ 539
++ + +E +F + + + + L+ Q Q+ E A AK ++ + +
Sbjct: 596 KVSFSKGLGTET---AEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAK 652
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI-NVLEEKQREEIKLYRLQLAQA 598
L + +E EN +++ ++ + E+QH +E+ + L + Q EIK+ L++ QA
Sbjct: 653 LMKVIKEKENS--------LEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQA 704
Score = 39.9 bits (89), Expect = 0.028
Identities = 64/325 (19%), Positives = 144/325 (44%), Gaps = 35/325 (10%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRV---------V 337
+ +RA +K E L +L ED+ + A E+ ++ E+E R
Sbjct: 982 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQT 1041
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNT--ELDNVNVMLSNK 394
A+DA + E +TL D + +LQNE +L+E L EL+ +L+ +
Sbjct: 1042 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1101
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD--STKSNIT---ELNKRIQS 449
+++++ ++ +T+ + Q + + L+E E K A + ++ +T +L +
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSALQE--ENVKLAEELGRSRDEVTSHQKLEEERSV 1159
Query: 450 VNDETLLLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNE--- 502
+N++ L + + +EE++ ++ L EK + ++ + L E
Sbjct: 1160 LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENAS 1219
Query: 503 VKTLRQHLE-LQKNELKCHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
K+L ++ L+ +++K + K LE + ++ + + + D R +E+ I D
Sbjct: 1220 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI-D 1278
Query: 561 SFNKQILRIEEQH---KLEINVLEE 582
N I+ ++ ++ K+++ ++ E
Sbjct: 1279 FLNSVIVDLQRKNQDLKMKVEMMSE 1303
Score = 39.1 bits (87), Expect = 0.049
Identities = 63/319 (19%), Positives = 130/319 (40%), Gaps = 19/319 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
A+ V R+ ++KL + + N L ++ R+ L M + + K
Sbjct: 821 AVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 879
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEI-DVLKE 403
E+++ + + ++ D + ++ +E + E E+L +L N S K I D+ +
Sbjct: 880 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET------LLL 457
+ K+ + K LE L + +++ + EL R + ET +L
Sbjct: 940 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 999
Query: 458 TQERDLL--KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++ LL + K+ R + + Q+L E + Q +E K ++ ++ + Q + +K
Sbjct: 1000 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQ-AEKAKAAQTAEDAMQIMEQ-MTKEKT 1057
Query: 516 ELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEE 571
E + KQ + +L +E + E+ L EN ++ F K+I +++
Sbjct: 1058 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1117
Query: 572 QHKLEINVLEEKQREEIKL 590
+ L Q E +KL
Sbjct: 1118 AAAQKSQQLSALQEENVKL 1136
Score = 35.5 bits (78), Expect = 0.60
Identities = 45/226 (19%), Positives = 101/226 (44%), Gaps = 12/226 (5%)
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S T L + ++ L ERDL +++V + S IEQ+L ++ + + + +
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENN 557
++++T+ + + +K EL +++ + + +E + + + E+ A + E +
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEV---ATVSEKS 464
Query: 558 IVDSFNKQI-LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR--R 614
+ K + LR++E +L + K ++ + L L Q ++ L+ K+E R
Sbjct: 465 RIMELEKDLALRVQEVAELRRRLESNKPAGDVDM-SLSLLQ---EISSLQEKLEVTRTDH 520
Query: 615 RRGETAARLH-AALQAHWRHALRILAAPHHDLGTHSHSTPSNVSEH 659
+R T+ + H A + + ++ L L + S S + EH
Sbjct: 521 QREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKL-EH 565
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 56.4 bits (130), Expect = 3e-07
Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 35/457 (7%)
Query: 187 ATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGY 246
AT+ S N+ LK EN + + ++K I S ++ EL + G
Sbjct: 594 ATEKLS-KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGLGT 651
Query: 247 NRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREA 305
+ ++ ++E+ RL +H I A M+ RAK + K +E
Sbjct: 652 ETAEFAELKTQIEKMRLDYQH---EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKEN 708
Query: 306 WLRLTNS-LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
L S LD+AED+H +E + +++ + + + + +E K +D
Sbjct: 709 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC-NEQTKVID------- 760
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
++ K+ EE+L +LD + S E+ L++ + + K L + KN E
Sbjct: 761 ---NFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHL-EIEKNAES 815
Query: 425 ALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ + +T L + + V+ L +E +LK K E +++ +
Sbjct: 816 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 875
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL--------ELQKNELKCHYQKQLEDAVLAKLQE 535
E N+ + ++ + L ++++ LR++L E + E + K+ + +A++ +
Sbjct: 876 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 935
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV------LEEKQREEIK 589
+M ++ RLKE ++ + K E L+ ++ E+ Q+E K
Sbjct: 936 MSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAK 995
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ + + KL LE K+E + E AR A
Sbjct: 996 KHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 1032
Score = 46.0 bits (104), Expect = 4e-04
Identities = 64/370 (17%), Positives = 166/370 (44%), Gaps = 35/370 (9%)
Query: 287 VAMKVDRAKDAAISK-LREAWLRLTNSLDRAED--RHRKALEKMICEVENFRVVADDAQK 343
+ + +K ++I++ L+ L+LTN + + + ++ LEK E++ + +A +
Sbjct: 809 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK---ELQILKEKFAEASE 865
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
+ + + +T++ H +++ L ++ + L E L +++ +++++ KE
Sbjct: 866 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL-ADMEAKFREKDEREEQLIKAKE 924
Query: 404 NYDT----VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI----QSVNDETL 455
+ +M+++ + + + + L ++ + + +T+ N+ +S+ D T+
Sbjct: 925 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 984
Query: 456 LLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL- 510
Q + K EE+ + + +E+++ NQC E+ + + +E KT + +
Sbjct: 985 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 1044
Query: 511 -ELQK----NELKCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNIVDSFNK 564
LQK E K ++ +L +L+E ++Q D+A+ + DA + +
Sbjct: 1045 QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTE 1104
Query: 565 QILRIEEQHKL------EINVLEE---KQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+ +E+ + E++ L+E K EE+ + L +K+ ++E ++
Sbjct: 1105 TLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1164
Query: 616 RGETAARLHA 625
+ + +L A
Sbjct: 1165 AAQKSQQLSA 1174
Score = 40.7 bits (91), Expect = 0.016
Identities = 65/325 (20%), Positives = 144/325 (44%), Gaps = 35/325 (10%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVAD------- 339
+ +RA +K E L +L ED+ + A E+ ++ E+E R AD
Sbjct: 1028 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1087
Query: 340 --DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNT--ELDNVNVMLSNK 394
DA + E +TL D + +LQNE +L+E L EL+ +L+ +
Sbjct: 1088 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1147
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD--STKSNIT---ELNKRIQS 449
+++++ ++ +T+ + Q + + L+E E K A + ++ +T +L +
Sbjct: 1148 NQKMEEFRKEIETLKQAAAQKSQQLSALQE--ENVKLAEELGRSRDEVTSHQKLEEERSV 1205
Query: 450 VNDETLLLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNE--- 502
+N++ L + + +EE++ ++ L EK + ++ + L E
Sbjct: 1206 LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENAS 1265
Query: 503 VKTLRQHLE-LQKNELKCHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
K+L ++ L+ +++K + K LE + ++ + + + D R +E+ I D
Sbjct: 1266 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI-D 1324
Query: 561 SFNKQILRIEEQH---KLEINVLEE 582
N I+ ++ ++ K+++ ++ E
Sbjct: 1325 FLNSVIVDLQRKNQDLKMKVEMMSE 1349
Score = 39.9 bits (89), Expect = 0.028
Identities = 71/326 (21%), Positives = 139/326 (42%), Gaps = 43/326 (13%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
L++ E+ RK +E + VE + D ++K+ E L H + +Q
Sbjct: 428 LNQLEEEKRK-VEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLF 486
Query: 373 KKSLEEQLNTELDNVNV-MLSNKDKEIDVLKE---NYDTVMRLNKQLTDC---------- 418
+K+ ++L EL++ V +S K + +++ K+ V L ++L
Sbjct: 487 EKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSL 546
Query: 419 -----VKNLEEALEKEKFAHDSTKSNITE--------LNKRIQSVNDETLLLTQERDLLK 465
+ +L+E LE + H +++ E K I+++ T L++E + LK
Sbjct: 547 SLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLK 606
Query: 466 SKV---NEERSRCAVIEQQLCE----KQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNEL 517
SK+ N+E S + + E Q E LK +T L+ Q ++
Sbjct: 607 SKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKM 666
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK----ENNIVDSFNKQILRIEEQH 573
+ YQ ++E+ L Q+ + E E +K + N +++ ++ + E+QH
Sbjct: 667 RLDYQHEIEN--LQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQH 724
Query: 574 KLEI-NVLEEKQREEIKLYRLQLAQA 598
+E+ + L + Q EIK+ L++ QA
Sbjct: 725 LVEMEDTLNKLQEAEIKVKELEVLQA 750
Score = 38.3 bits (85), Expect = 0.085
Identities = 62/319 (19%), Positives = 129/319 (40%), Gaps = 19/319 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
A+ V R+ ++KL + + N L ++ R+ L M + + K
Sbjct: 867 AVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 925
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEI-DVLKE 403
E+++ + + ++ D + ++ +E + E E+L +L N S K I D+ +
Sbjct: 926 LENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 985
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET------LLL 457
+ K+ + K LE L + +++ + EL R + ET +L
Sbjct: 986 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1045
Query: 458 TQERDLL--KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++ LL + K+ R + + Q+L E + Q + K ++ ++ + Q + +K
Sbjct: 1046 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKA-KAAQTAEDAMQIMEQ-MTKEKT 1103
Query: 516 ELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEE 571
E + KQ + +L +E + E+ L EN ++ F K+I +++
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 572 QHKLEINVLEEKQREEIKL 590
+ L Q E +KL
Sbjct: 1164 AAAQKSQQLSALQEENVKL 1182
Score = 35.5 bits (78), Expect = 0.60
Identities = 38/194 (19%), Positives = 88/194 (45%), Gaps = 6/194 (3%)
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S T L + ++ L ERDL +++V + S IEQ+L ++ + + + +
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND-ARLKEN 556
++++T+ + + +K EL +++ + + +E + + + E ++ + EN
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPEN 467
Query: 557 NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+ +I +E+ E ++ QRE L ++A +EK ++E +E R
Sbjct: 468 TQTKLEHARIKELEQSLLFEKTKADKLQRE---LEDTRVATVSEKSRIME--LEKDLALR 522
Query: 617 GETAARLHAALQAH 630
+ A L L+++
Sbjct: 523 VQEVAELRRRLESN 536
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 56.4 bits (130), Expect = 3e-07
Identities = 67/301 (22%), Positives = 139/301 (46%), Gaps = 30/301 (9%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D ++ K R + RL + ++ D ++ + K C N +V + A+ T+
Sbjct: 33 DKSLEKFRIEYERLHAVMKKSYDNEKRLMAK--CRELNAEIVVNSAKVATA--------- 81
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE-IDVLKENYDTVMRLNKQ 414
L L+ D Q L+ E + + +++ D K KE I LKE + +L +Q
Sbjct: 82 LKLSQDDQTTIASLKKEIEKAWKMVDSAYDK-----EQKAKETILALKEEIVNLTKLVEQ 136
Query: 415 LT----DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ D N+ + L +F + TK L++ ++ Q+++ +SK
Sbjct: 137 GSGLSMDQHSNIRDLL---RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
E + + +Q++ ++QN+ S +K + L+ E+K ++ ++ ++ E+K +Q
Sbjct: 194 EHA-ISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA--LQQYVQKSK 250
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL-EEKQREEIK 589
+LQ+ ++QL E+++ N+ KE N ++ + EQH L L +E Q++ ++
Sbjct: 251 EELQKLEQQL--KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALE 308
Query: 590 L 590
L
Sbjct: 309 L 309
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/347 (17%), Positives = 141/347 (40%), Gaps = 13/347 (3%)
Query: 253 DIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNS 312
D+++ +EE K + ++ + +R+K+ A + + +
Sbjct: 150 DLLRFKEEVTKER--DQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQR 207
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+ A RK EK+ E++ + D Q + + + K+ + + Q K +Q E
Sbjct: 208 QNEASREFRKK-EKLEKELKQIQADMDSRQTEIKALQQYVQKSKE---ELQ-KLEQQLKE 262
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA 432
+K L E+ EL+ + + +E + + + + N+Q +K EE + + +
Sbjct: 263 QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
+++K++ D+ + Q ++ LK+++ ++Q + E+
Sbjct: 323 IGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDEL 382
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMEND 550
L++ D L+ + + Q + +K H Q + LE + E Q+Q + +E +
Sbjct: 383 LRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQ-RKIIFHLEKE 441
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
N D K ++ +E+ E + + +++ EIKL + Q
Sbjct: 442 RDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQ 488
Score = 42.7 bits (96), Expect = 0.004
Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 12/305 (3%)
Query: 316 AEDRHRKALEKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+++ +KALE E V R+ K +L+ T D + + + L+N+
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQI 358
Query: 374 KSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LE ++ + D +E D+L +N + ++ TD VK E+A +
Sbjct: 359 VGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLE 418
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ K + K I + E + L KV V E Q+ + + + +
Sbjct: 419 GEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIA 478
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E K N + +R L L Q ++ D + KL+ Q+D E++ D
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNL-VEAQDEITD-MKRKLKIMIHQVD----ELKED 532
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
KE+ +V +Q RIE++ + L++ +++ ++ Q AE+ LL E
Sbjct: 533 ISAKESALVKLHLEQ-QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Query: 611 CQRRR 615
R
Sbjct: 592 ADGER 596
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 56.4 bits (130), Expect = 3e-07
Identities = 67/301 (22%), Positives = 139/301 (46%), Gaps = 30/301 (9%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D ++ K R + RL + ++ D ++ + K C N +V + A+ T+
Sbjct: 33 DKSLEKFRIEYERLHAVMKKSYDNEKRLMAK--CRELNAEIVVNSAKVATA--------- 81
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE-IDVLKENYDTVMRLNKQ 414
L L+ D Q L+ E + + +++ D K KE I LKE + +L +Q
Sbjct: 82 LKLSQDDQTTIASLKKEIEKAWKMVDSAYDK-----EQKAKETILALKEEIVNLTKLVEQ 136
Query: 415 LT----DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ D N+ + L +F + TK L++ ++ Q+++ +SK
Sbjct: 137 GSGLSMDQHSNIRDLL---RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
E + + +Q++ ++QN+ S +K + L+ E+K ++ ++ ++ E+K +Q
Sbjct: 194 EHA-ISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA--LQQYVQKSK 250
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL-EEKQREEIK 589
+LQ+ ++QL E+++ N+ KE N ++ + EQH L L +E Q++ ++
Sbjct: 251 EELQKLEQQL--KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALE 308
Query: 590 L 590
L
Sbjct: 309 L 309
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/347 (17%), Positives = 141/347 (40%), Gaps = 13/347 (3%)
Query: 253 DIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNS 312
D+++ +EE K + ++ + +R+K+ A + + +
Sbjct: 150 DLLRFKEEVTKER--DQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQR 207
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+ A RK EK+ E++ + D Q + + + K+ + + Q K +Q E
Sbjct: 208 QNEASREFRKK-EKLEKELKQIQADMDSRQTEIKALQQYVQKSKE---ELQ-KLEQQLKE 262
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA 432
+K L E+ EL+ + + +E + + + + N+Q +K EE + + +
Sbjct: 263 QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
+++K++ D+ + Q ++ LK+++ ++Q + E+
Sbjct: 323 IGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDEL 382
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMEND 550
L++ D L+ + + Q + +K H Q + LE + E Q+Q + +E +
Sbjct: 383 LRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQ-RKIIFHLEKE 441
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
N D K ++ +E+ E + + +++ EIKL + Q
Sbjct: 442 RDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQ 488
Score = 42.7 bits (96), Expect = 0.004
Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 12/305 (3%)
Query: 316 AEDRHRKALEKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+++ +KALE E V R+ K +L+ T D + + + L+N+
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQI 358
Query: 374 KSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LE ++ + D +E D+L +N + ++ TD VK E+A +
Sbjct: 359 VGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLE 418
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ K + K I + E + L KV V E Q+ + + + +
Sbjct: 419 GEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIA 478
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E K N + +R L L Q ++ D + KL+ Q+D E++ D
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNL-VEAQDEITD-MKRKLKIMIHQVD----ELKED 532
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
KE+ +V +Q RIE++ + L++ +++ ++ Q AE+ LL E
Sbjct: 533 ISAKESALVKLHLEQ-QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Query: 611 CQRRR 615
R
Sbjct: 592 ADGER 596
>AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 56.4 bits (130), Expect = 3e-07
Identities = 67/301 (22%), Positives = 139/301 (46%), Gaps = 30/301 (9%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D ++ K R + RL + ++ D ++ + K C N +V + A+ T+
Sbjct: 33 DKSLEKFRIEYERLHAVMKKSYDNEKRLMAK--CRELNAEIVVNSAKVATA--------- 81
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE-IDVLKENYDTVMRLNKQ 414
L L+ D Q L+ E + + +++ D K KE I LKE + +L +Q
Sbjct: 82 LKLSQDDQTTIASLKKEIEKAWKMVDSAYDK-----EQKAKETILALKEEIVNLTKLVEQ 136
Query: 415 LT----DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ D N+ + L +F + TK L++ ++ Q+++ +SK
Sbjct: 137 GSGLSMDQHSNIRDLL---RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
E + + +Q++ ++QN+ S +K + L+ E+K ++ ++ ++ E+K +Q
Sbjct: 194 EHA-ISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA--LQQYVQKSK 250
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL-EEKQREEIK 589
+LQ+ ++QL E+++ N+ KE N ++ + EQH L L +E Q++ ++
Sbjct: 251 EELQKLEQQL--KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALE 308
Query: 590 L 590
L
Sbjct: 309 L 309
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/347 (17%), Positives = 141/347 (40%), Gaps = 13/347 (3%)
Query: 253 DIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNS 312
D+++ +EE K + ++ + +R+K+ A + + +
Sbjct: 150 DLLRFKEEVTKER--DQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQR 207
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+ A RK EK+ E++ + D Q + + + K+ + + Q K +Q E
Sbjct: 208 QNEASREFRKK-EKLEKELKQIQADMDSRQTEIKALQQYVQKSKE---ELQ-KLEQQLKE 262
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA 432
+K L E+ EL+ + + +E + + + + N+Q +K EE + + +
Sbjct: 263 QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
+++K++ D+ + Q ++ LK+++ ++Q + E+
Sbjct: 323 IGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDEL 382
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMEND 550
L++ D L+ + + Q + +K H Q + LE + E Q+Q + +E +
Sbjct: 383 LRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQ-RKIIFHLEKE 441
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
N D K ++ +E+ E + + +++ EIKL + Q
Sbjct: 442 RDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQ 488
Score = 42.7 bits (96), Expect = 0.004
Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 12/305 (3%)
Query: 316 AEDRHRKALEKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+++ +KALE E V R+ K +L+ T D + + + L+N+
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQI 358
Query: 374 KSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LE ++ + D +E D+L +N + ++ TD VK E+A +
Sbjct: 359 VGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLE 418
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ K + K I + E + L KV V E Q+ + + + +
Sbjct: 419 GEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIA 478
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E K N + +R L L Q ++ D + KL+ Q+D E++ D
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNL-VEAQDEITD-MKRKLKIMIHQVD----ELKED 532
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
KE+ +V +Q RIE++ + L++ +++ ++ Q AE+ LL E
Sbjct: 533 ISAKESALVKLHLEQ-QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Query: 611 CQRRR 615
R
Sbjct: 592 ADGER 596
>AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein.
Length = 872
Score = 56.4 bits (130), Expect = 3e-07
Identities = 67/301 (22%), Positives = 139/301 (46%), Gaps = 30/301 (9%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D ++ K R + RL + ++ D ++ + K C N +V + A+ T+
Sbjct: 33 DKSLEKFRIEYERLHAVMKKSYDNEKRLMAK--CRELNAEIVVNSAKVATA--------- 81
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE-IDVLKENYDTVMRLNKQ 414
L L+ D Q L+ E + + +++ D K KE I LKE + +L +Q
Sbjct: 82 LKLSQDDQTTIASLKKEIEKAWKMVDSAYDK-----EQKAKETILALKEEIVNLTKLVEQ 136
Query: 415 LT----DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ D N+ + L +F + TK L++ ++ Q+++ +SK
Sbjct: 137 GSGLSMDQHSNIRDLL---RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
E + + +Q++ ++QN+ S +K + L+ E+K ++ ++ ++ E+K +Q
Sbjct: 194 EHA-ISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA--LQQYVQKSK 250
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL-EEKQREEIK 589
+LQ+ ++QL E+++ N+ KE N ++ + EQH L L +E Q++ ++
Sbjct: 251 EELQKLEQQL--KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALE 308
Query: 590 L 590
L
Sbjct: 309 L 309
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/347 (17%), Positives = 141/347 (40%), Gaps = 13/347 (3%)
Query: 253 DIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNS 312
D+++ +EE K + ++ + +R+K+ A + + +
Sbjct: 150 DLLRFKEEVTKER--DQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQR 207
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+ A RK EK+ E++ + D Q + + + K+ + + Q K +Q E
Sbjct: 208 QNEASREFRKK-EKLEKELKQIQADMDSRQTEIKALQQYVQKSKE---ELQ-KLEQQLKE 262
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA 432
+K L E+ EL+ + + +E + + + + N+Q +K EE + + +
Sbjct: 263 QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
+++K++ D+ + Q ++ LK+++ ++Q + E+
Sbjct: 323 IGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDEL 382
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMEND 550
L++ D L+ + + Q + +K H Q + LE + E Q+Q + +E +
Sbjct: 383 LRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQ-RKIIFHLEKE 441
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
N D K ++ +E+ E + + +++ EIKL + Q
Sbjct: 442 RDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQ 488
Score = 42.7 bits (96), Expect = 0.004
Identities = 65/305 (21%), Positives = 120/305 (39%), Gaps = 12/305 (3%)
Query: 316 AEDRHRKALEKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+++ +KALE E V R+ K +L+ T D + + + L+N+
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQI 358
Query: 374 KSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LE ++ + D +E D+L +N + ++ TD VK E+A +
Sbjct: 359 VGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLE 418
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ K + K I + E + L KV V E Q+ + + + +
Sbjct: 419 GEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIA 478
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E K N + +R L L Q ++ D + KL+ Q+D E++ D
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNL-VEAQDEITD-MKRKLKIMIHQVD----ELKED 532
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
KE+ +V +Q RIE++ + L++ +++ ++ Q AE+ LL E
Sbjct: 533 ISAKESALVKLHLEQ-QRIEKEKETLKAELQKLRQQALETKHFIEKQEAEERKLLRIIAE 591
Query: 611 CQRRR 615
R
Sbjct: 592 ADGER 596
>AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens
cDNA FLJ35908 fis, clone TESTI2009935. ).
Length = 550
Score = 56.4 bits (130), Expect = 3e-07
Identities = 67/301 (22%), Positives = 139/301 (46%), Gaps = 30/301 (9%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D ++ K R + RL + ++ D ++ + K C N +V + A+ T+
Sbjct: 33 DKSLEKFRIEYERLHAVMKKSYDNEKRLMAK--CRELNAEIVVNSAKVATA--------- 81
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE-IDVLKENYDTVMRLNKQ 414
L L+ D Q L+ E + + +++ D K KE I LKE + +L +Q
Sbjct: 82 LKLSQDDQTTIASLKKEIEKAWKMVDSAYDK-----EQKAKETILALKEEIVNLTKLVEQ 136
Query: 415 LT----DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ D N+ + L +F + TK L++ ++ Q+++ +SK
Sbjct: 137 GSGLSMDQHSNIRDLL---RFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
E + + +Q++ ++QN+ S +K + L+ E+K ++ ++ ++ E+K +Q
Sbjct: 194 EHA-ISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKA--LQQYVQKSK 250
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL-EEKQREEIK 589
+LQ+ ++QL E+++ N+ KE N ++ + EQH L L +E Q++ ++
Sbjct: 251 EELQKLEQQL--KEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALE 308
Query: 590 L 590
L
Sbjct: 309 L 309
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/347 (17%), Positives = 141/347 (40%), Gaps = 13/347 (3%)
Query: 253 DIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNS 312
D+++ +EE K + ++ + +R+K+ A + + +
Sbjct: 150 DLLRFKEEVTKER--DQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQR 207
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
+ A RK EK+ E++ + D Q + + + K+ + + Q K +Q E
Sbjct: 208 QNEASREFRKK-EKLEKELKQIQADMDSRQTEIKALQQYVQKSKE---ELQ-KLEQQLKE 262
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA 432
+K L E+ EL+ + + +E + + + + N+Q +K EE + + +
Sbjct: 263 QKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLD 322
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
+++K++ D+ + Q ++ LK+++ ++Q + E+
Sbjct: 323 IGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDEL 382
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMEND 550
L++ D L+ + + Q + +K H Q + LE + E Q+Q + +E +
Sbjct: 383 LRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQ-RKIIFHLEKE 441
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR---EEIKLYRLQ 594
N D K ++ +E+ E + + +++ EIKL + Q
Sbjct: 442 RDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQ 488
Score = 37.1 bits (82), Expect = 0.20
Identities = 53/249 (21%), Positives = 96/249 (38%), Gaps = 11/249 (4%)
Query: 316 AEDRHRKALEKMICE--VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
+++ +KALE E V R+ K +L+ T D + + + L+N+
Sbjct: 299 SQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQI 358
Query: 374 KSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LE ++ + D +E D+L +N + ++ TD VK E+A +
Sbjct: 359 VGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLE 418
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
+ K + K I + E + L KV V E Q+ + + + +
Sbjct: 419 GEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIA 478
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E K N + +R L L Q ++ D + KL+ Q+D E++ D
Sbjct: 479 ESEIKLKQQQNLYEAVRSDRNLYSKNL-VEAQDEITD-MKRKLKIMIHQVD----ELKED 532
Query: 551 ARLKENNIV 559
KE+ +V
Sbjct: 533 ISAKESALV 541
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 56.0 bits (129), Expect = 4e-07
Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 15/263 (5%)
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ +T + + K +Q EK+S+ +L L L + K L ++L
Sbjct: 102 ILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKE---LKL 158
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+++T NL++ + + ++N E K + +E + LK+ + +
Sbjct: 159 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEK----LKEELSASSARTQNLKADLQRK 214
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQKQLEDAVL 530
A ++++L + + Q +V K+ + +E K LR + EL+K + +C + ++ +
Sbjct: 215 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 274
Query: 531 AKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L+E ++++ A ++ E D +KE I D + L +EQ ++E + + E +
Sbjct: 275 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMTLEEQEQTQVEQDQVLEAKL 332
Query: 586 EEIKLYRLQLAQAAEKLGLLESK 608
EE++ +L + EK LE+K
Sbjct: 333 EEVERLATELEKWKEKCNDLETK 355
Score = 55.2 bits (127), Expect = 7e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 107 KVERSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 163
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 164 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 219
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 220 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 267
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 268 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 322
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 323 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 358
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/299 (24%), Positives = 142/299 (47%), Gaps = 34/299 (11%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA K ++E + Q + ++ E + + H QD L EK++L +QL
Sbjct: 2 KASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQD---DLLKEKETLIQQLK 58
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC----VKNLEEALEKEKFAHDSTK 437
EL NV L D +I + E + L + +T C +K LE LE +K +
Sbjct: 59 EELQEKNVTL---DVQIQHVVEGKRALSELTQGVT-CYKAKIKELETILETQKV----ER 110
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S+ +L + I + E+++L ER+L + E + L K+ + E + +
Sbjct: 111 SHSAKLEQDI--LEKESIILKLERNL--KEFQEHLQDSVKNTKDLNVKELKLKEEITQ-- 164
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
L N ++ ++ L+L++ E + + Q ++L++ + A Q +R+ E+ A LKE
Sbjct: 165 -LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE 223
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+ D+ KQI ++++ E++V+ R+E KL R+++ + +K +++ ++R
Sbjct: 224 -KLTDA-KKQIKQVQK----EVSVM----RDEDKLLRIKINELEKKKNQCSQELDMKQR 272
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 56.0 bits (129), Expect = 4e-07
Identities = 93/457 (20%), Positives = 184/457 (40%), Gaps = 35/457 (7%)
Query: 187 ATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGY 246
AT+ S N+ LK EN + + ++K I S ++ EL + G
Sbjct: 594 ATEKLS-KENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL-KVSFSKGLGT 651
Query: 247 NRGDKVDI-IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREA 305
+ ++ ++E+ RL +H I A M+ RAK + K +E
Sbjct: 652 ETAEFAELKTQIEKMRLDYQH---EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKEN 708
Query: 306 WLRLTNS-LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
L S LD+AED+H +E + +++ + + + + +E K +D
Sbjct: 709 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKC-NEQTKVID------- 760
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
++ K+ EE+L +LD + S E+ L++ + + K L + KN E
Sbjct: 761 ---NFTSQLKATEEKL-LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHL-EIEKNAES 815
Query: 425 ALEKEKFAH-DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ + +T L + + V+ L +E +LK K E +++ +
Sbjct: 816 SKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQ 875
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL--------ELQKNELKCHYQKQLEDAVLAKLQE 535
E N+ + ++ + L ++++ LR++L E + E + K+ + +A++ +
Sbjct: 876 ETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMK 935
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV------LEEKQREEIK 589
+M ++ RLKE ++ + K E L+ ++ E+ Q+E K
Sbjct: 936 MSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAK 995
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ + + KL LE K+E + E AR A
Sbjct: 996 KHEEEKKELERKLSDLEKKMETSHNQCQELKARYERA 1032
Score = 43.6 bits (98), Expect = 0.002
Identities = 63/370 (17%), Positives = 165/370 (44%), Gaps = 35/370 (9%)
Query: 287 VAMKVDRAKDAAISK-LREAWLRLTNSLDRAED--RHRKALEKMICEVENFRVVADDAQK 343
+ + +K ++I++ L+ L+LTN + + + ++ LEK E++ + +A +
Sbjct: 809 IEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEK---ELQILKEKFAEASE 865
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
+ + + +T++ H +++ L ++ + L E L +++ +++++ KE
Sbjct: 866 EAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENL-ADMEAKFREKDEREEQLIKAKE 924
Query: 404 NYDT----VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRI----QSVNDETL 455
+ +M+++ + + + L ++ + + +T+ N+ +S+ D T+
Sbjct: 925 KLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTV 984
Query: 456 LLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL- 510
Q + K EE+ + + +E+++ NQC E+ + + +E KT + +
Sbjct: 985 KAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEIL 1044
Query: 511 -ELQK----NELKCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNIVDSFNK 564
LQK E K ++ +L +L+E ++Q ++A+ + DA + +
Sbjct: 1045 QNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTE 1104
Query: 565 QILRIEEQHKL------EINVLEE---KQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+ +E+ + E++ L+E K EE+ + L +K+ ++E ++
Sbjct: 1105 TLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQA 1164
Query: 616 RGETAARLHA 625
+ + +L A
Sbjct: 1165 AAQKSQQLSA 1174
Score = 39.9 bits (89), Expect = 0.028
Identities = 71/326 (21%), Positives = 139/326 (42%), Gaps = 43/326 (13%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
L++ E+ RK +E + VE + D ++K+ E L H + +Q
Sbjct: 428 LNQLEEEKRK-VEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLF 486
Query: 373 KKSLEEQLNTELDNVNV-MLSNKDKEIDVLKE---NYDTVMRLNKQLTDC---------- 418
+K+ ++L EL++ V +S K + +++ K+ V L ++L
Sbjct: 487 EKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSL 546
Query: 419 -----VKNLEEALEKEKFAHDSTKSNITE--------LNKRIQSVNDETLLLTQERDLLK 465
+ +L+E LE + H +++ E K I+++ T L++E + LK
Sbjct: 547 SLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLK 606
Query: 466 SKV---NEERSRCAVIEQQLCE----KQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNEL 517
SK+ N+E S + + E Q E LK +T L+ Q ++
Sbjct: 607 SKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKM 666
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK----ENNIVDSFNKQILRIEEQH 573
+ YQ ++E+ L Q+ + E E +K + N +++ ++ + E+QH
Sbjct: 667 RLDYQHEIEN--LQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQH 724
Query: 574 KLEI-NVLEEKQREEIKLYRLQLAQA 598
+E+ + L + Q EIK+ L++ QA
Sbjct: 725 LVEMEDTLNKLQEAEIKVKELEVLQA 750
Score = 39.9 bits (89), Expect = 0.028
Identities = 64/325 (19%), Positives = 144/325 (44%), Gaps = 35/325 (10%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRV---------V 337
+ +RA +K E L +L ED+ + A E+ ++ E+E R
Sbjct: 1028 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQT 1087
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNT--ELDNVNVMLSNK 394
A+DA + E +TL D + +LQNE +L+E L EL+ +L+ +
Sbjct: 1088 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVE 1147
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD--STKSNIT---ELNKRIQS 449
+++++ ++ +T+ + Q + + L+E E K A + ++ +T +L +
Sbjct: 1148 NQKMEEFRKEIETLKQAAAQKSQQLSALQE--ENVKLAEELGRSRDEVTSHQKLEEERSV 1205
Query: 450 VNDETLLLTQERDLLKSKVNEERS----RCAVIEQQLCEKQNQCSEVLKKCDFLDNE--- 502
+N++ L + + +EE++ ++ L EK + ++ + L E
Sbjct: 1206 LNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENAS 1265
Query: 503 VKTLRQHLE-LQKNELKCHYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
K+L ++ L+ +++K + K LE + ++ + + + D R +E+ I D
Sbjct: 1266 AKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQI-D 1324
Query: 561 SFNKQILRIEEQH---KLEINVLEE 582
N I+ ++ ++ K+++ ++ E
Sbjct: 1325 FLNSVIVDLQRKNQDLKMKVEMMSE 1349
Score = 38.7 bits (86), Expect = 0.065
Identities = 63/319 (19%), Positives = 130/319 (40%), Gaps = 19/319 (5%)
Query: 288 AMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
A+ V R+ ++KL + + N L ++ R+ L M + + K
Sbjct: 867 AVSVQRSMQETVNKLHQKEEQF-NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEK 925
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEI-DVLKE 403
E+++ + + ++ D + ++ +E + E E+L +L N S K I D+ +
Sbjct: 926 LENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 985
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET------LLL 457
+ K+ + K LE L + +++ + EL R + ET +L
Sbjct: 986 AEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQ 1045
Query: 458 TQERDLL--KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++ LL + K+ R + + Q+L E + Q +E K ++ ++ + Q + +K
Sbjct: 1046 NLQKTLLDTEDKLKGAREENSGLLQELEELRKQ-AEKAKAAQTAEDAMQIMEQ-MTKEKT 1103
Query: 516 ELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEE 571
E + KQ + +L +E + E+ L EN ++ F K+I +++
Sbjct: 1104 ETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQ 1163
Query: 572 QHKLEINVLEEKQREEIKL 590
+ L Q E +KL
Sbjct: 1164 AAAQKSQQLSALQEENVKL 1182
Score = 35.5 bits (78), Expect = 0.60
Identities = 38/194 (19%), Positives = 88/194 (45%), Gaps = 6/194 (3%)
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S T L + ++ L ERDL +++V + S IEQ+L ++ + + + +
Sbjct: 348 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE 407
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND-ARLKEN 556
++++T+ + + +K EL +++ + + +E + + + E ++ + EN
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPEN 467
Query: 557 NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+ +I +E+ E ++ QRE L ++A +EK ++E +E R
Sbjct: 468 TQTKLEHARIKELEQSLLFEKTKADKLQRE---LEDTRVATVSEKSRIME--LEKDLALR 522
Query: 617 GETAARLHAALQAH 630
+ A L L+++
Sbjct: 523 VQEVAELRRRLESN 536
>AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 617
Score = 56.0 bits (129), Expect = 4e-07
Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 15/263 (5%)
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ +T + + K +Q EK+S+ +L L L + K L ++L
Sbjct: 64 ILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKE---LKL 120
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+++T NL++ + + ++N E K + +E + LK+ + +
Sbjct: 121 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEK----LKEELSASSARTQNLKADLQRK 176
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQKQLEDAVL 530
A ++++L + + Q +V K+ + +E K LR + EL+K + +C + ++ +
Sbjct: 177 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 236
Query: 531 AKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L+E ++++ A ++ E D +KE I D + L +EQ ++E + + E +
Sbjct: 237 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMTLEEQEQTQVEQDQVLEAKL 294
Query: 586 EEIKLYRLQLAQAAEKLGLLESK 608
EE++ +L + EK LE+K
Sbjct: 295 EEVERLATELEKWKEKCNDLETK 317
Score = 55.2 bits (127), Expect = 7e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 69 KVERSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 125
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 126 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 181
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 182 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 229
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 230 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 284
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 285 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 320
Score = 46.8 bits (106), Expect = 2e-04
Identities = 66/261 (25%), Positives = 128/261 (49%), Gaps = 34/261 (13%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC- 418
H QD L EK++L +QL EL NV L D +I + E + L + +T C
Sbjct: 2 HKNQD---DLLKEKETLIQQLKEELQEKNVTL---DVQIQHVVEGKRALSELTQGVT-CY 54
Query: 419 ---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+K LE LE +K +S+ +L + I + E+++L ER+L + E
Sbjct: 55 KAKIKELETILETQKV----ERSHSAKLEQDI--LEKESIILKLERNL--KEFQEHLQDS 106
Query: 476 AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKL 533
+ L K+ + E + + L N ++ ++ L+L++ E + + Q ++L++ + A
Sbjct: 107 VKNTKDLNVKELKLKEEITQ---LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASS 163
Query: 534 QEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
Q +R+ E+ A LKE + D+ KQI ++++ E++V+ R+E KL R+
Sbjct: 164 ARTQNLKADLQRKEEDYADLKE-KLTDA-KKQIKQVQK----EVSVM----RDEDKLLRI 213
Query: 594 QLAQAAEKLGLLESKVECQRR 614
++ + +K +++ ++R
Sbjct: 214 KINELEKKKNQCSQELDMKQR 234
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 56.0 bits (129), Expect = 4e-07
Identities = 69/358 (19%), Positives = 162/358 (45%), Gaps = 24/358 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
M+V + D A+ L + + + E ++ +E+M + A++++ +
Sbjct: 526 MEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLY 585
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL-DNVNVMLSNKDKEIDV--LKENY 405
ESEL ++ A +++ K + Q++ ++Q E+ + + N ++++ + L+E
Sbjct: 586 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 645
Query: 406 DTVMRLNKQLTDCVKNLEEA-------LEKEKFAHDST---KSNITELNKRIQSVNDETL 455
+ ++ + + T+ ++N+ +A LEK + DS+ + + E +R S+ ++
Sbjct: 646 EKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEERRHSLENKVK 705
Query: 456 LL-TQER--DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL 512
L T ER + LK + + + + ++ E + + E L+ +K QH E
Sbjct: 706 RLETMERRENRLKDDIQTKSQQIQQMADKILELEEKHREAQVSAQHLEVHLKQKEQHYEE 765
Query: 513 QKNELKCHYQKQLEDAVLAK--LQEFQEQL-DRAEREMENDARLKE-NNIVDSFNKQILR 568
+ L +K L D + +Q +E+ ++ + E A + ++ + S ++I+
Sbjct: 766 KIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVE 825
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES---KVECQRRRRGETAARL 623
+ E +KL N QR +K +++ ++ LE+ K+E Q R+ E ++
Sbjct: 826 LSEANKLAANSSLFTQR-NMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKI 882
Score = 55.6 bits (128), Expect = 5e-07
Identities = 78/310 (25%), Positives = 145/310 (46%), Gaps = 48/310 (15%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID 399
D+ KTS E +L D QDKC +++ E +L+ + V +LS K+ E+
Sbjct: 439 DSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEM----TRLHRRVSEVEAVLSQKEVELK 494
Query: 400 VLKENYDTVMR-LNKQLTDCVKNLEEALEKEKF--AHDSTKS-----NITELNKRIQSVN 451
+ + + L +T+C +L+ +LE+ + + + K+ +I E ++++Q +
Sbjct: 495 ASETQRSLLEQDLATYITEC-SSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIK 553
Query: 452 D-ETLLLTQERDLLKSKVNEE----RSRCAVIEQQLCEKQNQCSEVLKK---CDF----- 498
+ E +E L+ +++ E+ R R + E +L E + E +K C
Sbjct: 554 EQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKA 613
Query: 499 LDNEVKTLRQHLELQK----NELKC-HYQKQLEDAVLAK------LQEFQEQLDRAEREM 547
D + ++ +L+K +LK Q++LE AV A LQ ++ +RAERE+
Sbjct: 614 KDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAEREL 673
Query: 548 ENDARLKENNIVDSFNKQILRIEE-QHKLEINV--LEEKQREE------IKLYRLQLAQA 598
E ++++ + K+++ EE +H LE V LE +R E I+ Q+ Q
Sbjct: 674 EKLQNREDSS--EGIRKKLVEAEERRHSLENKVKRLETMERRENRLKDDIQTKSQQIQQM 731
Query: 599 AEKLGLLESK 608
A+K+ LE K
Sbjct: 732 ADKILELEEK 741
Score = 52.4 bits (120), Expect = 5e-06
Identities = 75/308 (24%), Positives = 142/308 (46%), Gaps = 26/308 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKTLDLAHDY-QDKCKQLQN 371
A D ++LE+ I E+ +A ++ ++ + E+ L Y + + +L+
Sbjct: 811 AMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEA 870
Query: 372 EKKSLEEQL----NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE--- 424
+ + LEEQL + + + N +L + + +V E+ + + L +QLT+ +L+E
Sbjct: 871 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERES 930
Query: 425 ---ALEKEKFAHDST-KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
AL+ + A +S + TEL + +E LT RD ++ K + R+ C VI
Sbjct: 931 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI-T 989
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQ 539
L E+ NQ +E + L+N+ L + L+ Q + E D + ++ E + Q
Sbjct: 990 DLEEQLNQLTEDNAE---LNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 1046
Query: 540 LDRAEREME---NDARLKENNIVD--SFNKQILRIEEQHKLEINVL-EEKQREEIKLYRL 593
L ++ ME + E ++D + N ++L E Q + +VL +EK + E ++ L
Sbjct: 1047 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 1106
Query: 594 QLAQAAEK 601
Q EK
Sbjct: 1107 QRMLDTEK 1114
Score = 37.1 bits (82), Expect = 0.20
Identities = 76/328 (23%), Positives = 136/328 (41%), Gaps = 43/328 (13%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKA-LEKMICEVENFRVVADDAQKKTSHFESELYKTLD 357
I+ L E +LT D AE ++ L K + E + + H E+ +
Sbjct: 988 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 1045
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+ + L+ LEEQ+ +L+ +N L K+++ E + +V+ K +
Sbjct: 1046 QLTSQKQTMEALKTTCTMLEEQV-MDLEALNDELLEKERQW----EAWRSVLGDEKSQFE 1100
Query: 418 C-VKNLEEALEKEKFAHDSTKSNITELNKRIQ-SVND---ETLLLTQ-------ERDLLK 465
C V+ L+ L+ EK + ITE + ++ +V + E L L Q + + L
Sbjct: 1101 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 1160
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+N+ + A++E Q + + L E L+Q ++LQKN
Sbjct: 1161 DKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNH--------- 1211
Query: 526 EDAVLAKLQEFQEQLDRAE--REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ Q QE LDRA+ + +D + NI Q+L E+ K+E + +
Sbjct: 1212 ---IFRLTQGLQEALDRADLLKTERSDLEYQLENI------QVLYSHEKVKMEGTI--SQ 1260
Query: 584 QREEIKLYRLQLAQ-AAEKLGLLESKVE 610
Q + I + ++ Q A +K GL + E
Sbjct: 1261 QTKLIDFLQAKMDQPAKKKKGLFSRRKE 1288
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 56.0 bits (129), Expect = 4e-07
Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 15/263 (5%)
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ +T + + K +Q EK+S+ +L L L + K L ++L
Sbjct: 465 ILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKE---LKL 521
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+++T NL++ + + ++N E K + +E + LK+ + +
Sbjct: 522 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEK----LKEELSASSARTQNLKADLQRK 577
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQKQLEDAVL 530
A ++++L + + Q +V K+ + +E K LR + EL+K + +C + ++ +
Sbjct: 578 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 637
Query: 531 AKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L+E ++++ A ++ E D +KE I D + L +EQ ++E + + E +
Sbjct: 638 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMTLEEQEQTQVEQDQVLEAKL 695
Query: 586 EEIKLYRLQLAQAAEKLGLLESK 608
EE++ +L + EK LE+K
Sbjct: 696 EEVERLATELEKWKEKCNDLETK 718
Score = 55.2 bits (127), Expect = 7e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 470 KVERSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 526
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 527 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 582
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 583 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 630
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 631 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 685
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 686 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 721
Score = 41.9 bits (94), Expect = 0.007
Identities = 95/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 119 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 178
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 179 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 232
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 233 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 289
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 290 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 345
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 346 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 404
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 405 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 464
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E + H K LE +L K + +L+R +E + + N D
Sbjct: 465 ILETQKVE-RSHSAK-LEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 513
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 514 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 563
Score = 34.7 bits (76), Expect = 1.1
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 29/257 (11%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K + ++EL KT +++ K+ +NE SL ++L T + + + I+++ +
Sbjct: 12 KFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSIKKIITQNQRIKELINIIDQ 71
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
DT+ +NL+ +E +D ++ +N ++ + +ET+ + ++
Sbjct: 72 KEDTINEF--------QNLKSLMENTFKCNDKADTSSLIINNKL--ICNETVEVPKDS-- 119
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KSK+ ER R E Q E + + +++ K+ E++ N
Sbjct: 120 -KSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKS----EEVRPN------IA 168
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLE 581
++ED + LQE E L +EN+ + E NKQI+ +++ L + N+
Sbjct: 169 EIED--IRVLQENNEGLRAFLLTIENELK-NEKEEKAELNKQIVHFQQELSLSEKKNLTL 225
Query: 582 EKQREEIKL-YRLQLAQ 597
K+ ++I+ Y + +A+
Sbjct: 226 SKEVQQIQSNYDIAIAE 242
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 56.0 bits (129), Expect = 4e-07
Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 15/263 (5%)
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ +T + + K +Q EK+S+ +L L L + K L ++L
Sbjct: 380 ILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKE---LKL 436
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+++T NL++ + + ++N E K + +E + LK+ + +
Sbjct: 437 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEK----LKEELSASSARTQNLKADLQRK 492
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQKQLEDAVL 530
A ++++L + + Q +V K+ + +E K LR + EL+K + +C + ++ +
Sbjct: 493 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 552
Query: 531 AKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L+E ++++ A ++ E D +KE I D + L +EQ ++E + + E +
Sbjct: 553 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMTLEEQEQTQVEQDQVLEAKL 610
Query: 586 EEIKLYRLQLAQAAEKLGLLESK 608
EE++ +L + EK LE+K
Sbjct: 611 EEVERLATELEKWKEKCNDLETK 633
Score = 55.2 bits (127), Expect = 7e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 385 KVERSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 441
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 442 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 497
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 498 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 545
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 546 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 600
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 601 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 636
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/299 (24%), Positives = 142/299 (47%), Gaps = 34/299 (11%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA K ++E + Q + ++ E + + H QD L EK++L +QL
Sbjct: 280 KASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEREHKNQD---DLLKEKETLIQQLK 336
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC----VKNLEEALEKEKFAHDSTK 437
EL NV L D +I + E + L + +T C +K LE LE +K +
Sbjct: 337 EELQEKNVTL---DVQIQHVVEGKRALSELTQGVT-CYKAKIKELETILETQKV----ER 388
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
S+ +L + I + E+++L ER+L + E + L K+ + E + +
Sbjct: 389 SHSAKLEQDI--LEKESIILKLERNL--KEFQEHLQDSVKNTKDLNVKELKLKEEITQ-- 442
Query: 498 FLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
L N ++ ++ L+L++ E + + Q ++L++ + A Q +R+ E+ A LKE
Sbjct: 443 -LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE 501
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+ D+ KQI ++++ E++V+ R+E KL R+++ + +K +++ ++R
Sbjct: 502 -KLTDA-KKQIKQVQK----EVSVM----RDEDKLLRIKINELEKKKNQCSQELDMKQR 550
Score = 42.7 bits (96), Expect = 0.004
Identities = 96/478 (20%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 34 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPSIAEIEDIRVLQE 93
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 94 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHSQQELSLSEKKNLTLSKEVQQI 147
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 148 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 204
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 205 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 260
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L +R +
Sbjct: 261 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKER-EHK 319
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 320 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 379
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E + H K LE +L K + +L+R +E + + N D
Sbjct: 380 ILETQKVE-RSHSAK-LEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 428
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 429 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 478
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 433 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 492
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 493 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 544
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 545 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 602
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 603 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 662
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 663 LEGLKQKQ 670
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 637 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 695
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 696 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 741
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 742 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 795
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 796 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 851
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 852 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 909
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 910 TECKLKDSEKKNLELLSEIEQL 931
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 497 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 553
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 554 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 613
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 614 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 672
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 673 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 704
>AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short
isoform protein.
Length = 1248
Score = 56.0 bits (129), Expect = 4e-07
Identities = 66/317 (20%), Positives = 139/317 (43%), Gaps = 30/317 (9%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A+ + R + K +E W R L E + + LEK + + ++ ++K
Sbjct: 383 ALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKD 442
Query: 346 SHFESELYKTLDLAHDYQ---DKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEID 399
+ L+ + + ++L N+K +E+ LN++ N+++ L + +
Sbjct: 443 IERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQ 502
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
+ V RL KQ K E L+K+ D I +L + +Q ++ + L
Sbjct: 503 QISGRLQDV-RLKKQTQ---KTELEVLDKQC---DLEIMEIKQLQQELQEYQNKLIYLVP 555
Query: 460 ERDLLKSKV------NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
E+ LL ++ N S +++ ++ EK+ C + ++ D L+ E + ++
Sbjct: 556 EKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSF 615
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
N+LKC ++D+VL L L N+ L + +++N Q L +E+ +
Sbjct: 616 NNQLKC---GNMDDSVLQCLLSLLSCL--------NNLFLLLKELRETYNTQQLALEQLY 664
Query: 574 KLEINVLEEKQREEIKL 590
K++ + L+E +R+ ++L
Sbjct: 665 KIKRDKLKEIERKRLEL 681
Score = 31.9 bits (69), Expect = 7.4
Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 514 KNELKCHYQK---QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
+++ K +Y++ +LE A +++ Q + +R ++ + + K+ + + K+ L +E
Sbjct: 363 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 422
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +LE E+QREE + ++ +AA++ + ++E +R RR E
Sbjct: 423 K--RLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 468
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 56.0 bits (129), Expect = 4e-07
Identities = 66/317 (20%), Positives = 139/317 (43%), Gaps = 30/317 (9%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A+ + R + K +E W R L E + + LEK + + ++ ++K
Sbjct: 383 ALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKD 442
Query: 346 SHFESELYKTLDLAHDYQ---DKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEID 399
+ L+ + + ++L N+K +E+ LN++ N+++ L + +
Sbjct: 443 IERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQ 502
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
+ V RL KQ K E L+K+ D I +L + +Q ++ + L
Sbjct: 503 QISGRLQDV-RLKKQTQ---KTELEVLDKQC---DLEIMEIKQLQQELQEYQNKLIYLVP 555
Query: 460 ERDLLKSKV------NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
E+ LL ++ N S +++ ++ EK+ C + ++ D L+ E + ++
Sbjct: 556 EKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSF 615
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
N+LKC ++D+VL L L N+ L + +++N Q L +E+ +
Sbjct: 616 NNQLKC---GNMDDSVLQCLLSLLSCL--------NNLFLLLKELRETYNTQQLALEQLY 664
Query: 574 KLEINVLEEKQREEIKL 590
K++ + L+E +R+ ++L
Sbjct: 665 KIKRDKLKEIERKRLEL 681
Score = 31.9 bits (69), Expect = 7.4
Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 514 KNELKCHYQK---QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
+++ K +Y++ +LE A +++ Q + +R ++ + + K+ + + K+ L +E
Sbjct: 363 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 422
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +LE E+QREE + ++ +AA++ + ++E +R RR E
Sbjct: 423 K--RLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 468
>AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein.
Length = 1329
Score = 56.0 bits (129), Expect = 4e-07
Identities = 66/317 (20%), Positives = 139/317 (43%), Gaps = 30/317 (9%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A+ + R + K +E W R L E + + LEK + + ++ ++K
Sbjct: 383 ALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKD 442
Query: 346 SHFESELYKTLDLAHDYQ---DKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEID 399
+ L+ + + ++L N+K +E+ LN++ N+++ L + +
Sbjct: 443 IERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQ 502
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
+ V RL KQ K E L+K+ D I +L + +Q ++ + L
Sbjct: 503 QISGRLQDV-RLKKQTQ---KTELEVLDKQC---DLEIMEIKQLQQELQEYQNKLIYLVP 555
Query: 460 ERDLLKSKV------NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
E+ LL ++ N S +++ ++ EK+ C + ++ D L+ E + ++
Sbjct: 556 EKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSEMDSF 615
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
N+LKC ++D+VL L L N+ L + +++N Q L +E+ +
Sbjct: 616 NNQLKC---GNMDDSVLQCLLSLLSCL--------NNLFLLLKELRETYNTQQLALEQLY 664
Query: 574 KLEINVLEEKQREEIKL 590
K++ + L+E +R+ ++L
Sbjct: 665 KIKRDKLKEIERKRLEL 681
Score = 31.9 bits (69), Expect = 7.4
Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 514 KNELKCHYQK---QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
+++ K +Y++ +LE A +++ Q + +R ++ + + K+ + + K+ L +E
Sbjct: 363 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 422
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +LE E+QREE + ++ +AA++ + ++E +R RR E
Sbjct: 423 K--RLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 468
>AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein
kinase alpha variant protein.
Length = 1702
Score = 56.0 bits (129), Expect = 4e-07
Identities = 59/248 (23%), Positives = 115/248 (46%), Gaps = 27/248 (10%)
Query: 354 KTLD--LAHD-YQDKCKQLQNEKKSLEEQLNTELDNVNVM---------LSNKDKEIDVL 401
+TLD LA + Y+ + K+L+ EK L +L V + ++KD EI L
Sbjct: 444 RTLDNNLATEAYERRIKRLEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNL 503
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE + +L KQ+T+ +LE+ LE+ ++ + + + ++I++ + L QER
Sbjct: 504 KEE---IEKLRKQVTES-SHLEQQLEEA----NAVRQELDDAFRQIKAYEKQIKTLQQER 555
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ L ++ + R ++L K C L +F++ + H + QK
Sbjct: 556 EDLNKELVQASERLKNQSKEL--KDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRD 613
Query: 522 QKQLEDAVLAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLE 576
+++ D V+ K++ +++L R ER E+ +A E + +Q +Q + E
Sbjct: 614 KEEEVDLVMQKVESLRQELRRTERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENE 673
Query: 577 INVLEEKQ 584
+ L++KQ
Sbjct: 674 LEGLKQKQ 681
Score = 41.5 bits (93), Expect = 0.009
Identities = 67/322 (20%), Positives = 154/322 (47%), Gaps = 34/322 (10%)
Query: 288 AMKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQK 343
A+ + +KD + + E + + L N L+ + + + + +C +E+ + + D +K
Sbjct: 648 ALAAEASKDRKLREQSEHYSKQLENELEGLKQK-QISYSPGVCSIEHQQEITKLKTDLEK 706
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K+ +E EL K + H NE K+L+++L+ D+ L+ +KEI +LK+
Sbjct: 707 KSIFYEEELSKREGI-H---------ANEIKNLKKELH---DSEGQQLA-LNKEIMILKD 752
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+L K + EE + K ++ K +TE NK++ S D+ L + +
Sbjct: 753 ------KLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSI 806
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
++ EE A ++ + + Q +E+++ ++ +E K R +L+ +++ +
Sbjct: 807 HNQQLEEEVKDLADKKESVAHWEAQITEIIQ---WVSDE-KDARGYLQALASKMTEELEA 862
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEI-NVL 580
++ + + ++ R + ++ ARL+ + +D+ KQ ++ EE +K++ N++
Sbjct: 863 LRNSSLGTRATDMPWKMRRFAK-LDMSARLELQSALDAEIRAKQAIQ-EELNKVKASNII 920
Query: 581 EEKQREEIKLYRLQLAQAAEKL 602
E + ++ + L+L E+L
Sbjct: 921 TECKLKDSEKKNLELLSEIEQL 942
Score = 39.5 bits (88), Expect = 0.037
Identities = 48/212 (22%), Positives = 92/212 (43%), Gaps = 21/212 (9%)
Query: 364 DKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+K ++ E LE+QL ELD+ + +K+I L++ + LNK+L
Sbjct: 508 EKLRKQVTESSHLEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQERED---LNKELVQ 564
Query: 418 CVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLT-------QERDLLKSK 467
+ L+ ++ K AH K E+N+R+ ++ + L +E DL+ K
Sbjct: 565 ASERLKNQSKELKDAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQK 624
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ-KNELKCHYQKQLE 526
V R E+ E + +E L D +++ +H Q +NEL+ QKQ+
Sbjct: 625 VESLRQELRRTERAKKELEVH-TEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQIS 683
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+ E Q+++ + + ++E + E +
Sbjct: 684 YSPGVCSIEHQQEITKLKTDLEKKSIFYEEEL 715
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 56.0 bits (129), Expect = 4e-07
Identities = 56/263 (21%), Positives = 121/263 (46%), Gaps = 15/263 (5%)
Query: 352 LYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
+ +T + + K +Q EK+S+ +L L L + K L ++L
Sbjct: 1169 ILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKE---LKL 1225
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+++T NL++ + + ++N E K + +E + LK+ + +
Sbjct: 1226 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEK----LKEELSASSARTQNLKADLQRK 1281
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQKQLEDAVL 530
A ++++L + + Q +V K+ + +E K LR + EL+K + +C + ++ +
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 1341
Query: 531 AKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L+E ++++ A ++ E D +KE I D + L +EQ ++E + + E +
Sbjct: 1342 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMTLEEQEQTQVEQDQVLEAKL 1399
Query: 586 EEIKLYRLQLAQAAEKLGLLESK 608
EE++ +L + EK LE+K
Sbjct: 1400 EEVERLATELEKWKEKCNDLETK 1422
Score = 55.2 bits (127), Expect = 7e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 1174 KVERSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1230
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 1231 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1286
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 1287 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 1334
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 1335 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 1389
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 1390 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 1425
Score = 41.9 bits (94), Expect = 0.007
Identities = 95/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 823 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 882
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 883 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 936
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 937 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 993
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 994 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 1049
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 1050 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 1108
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 1109 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 1168
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E + H K LE +L K + +L+R +E + + N D
Sbjct: 1169 ILETQKVE-RSHSAK-LEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 1217
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 1218 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1267
Score = 34.7 bits (76), Expect = 1.1
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 29/257 (11%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K + ++EL KT +++ K+ +NE SL ++L T + + + I+++ +
Sbjct: 716 KFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELKTSIKKIITQNQRIKELINIIDQ 775
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
DT+ +NL+ +E +D ++ +N ++ + +ET+ + ++
Sbjct: 776 KEDTINEF--------QNLKSLMENTFKCNDKADTSSLIINNKL--ICNETVEVPKDS-- 823
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KSK+ ER R E Q E + + +++ K+ E++ N
Sbjct: 824 -KSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKS----EEVRPN------IA 872
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLE 581
++ED + LQE E L +EN+ + E NKQI+ +++ L + N+
Sbjct: 873 EIED--IRVLQENNEGLRAFLLTIENELK-NEKEEKAELNKQIVHFQQELSLSEKKNLTL 929
Query: 582 EKQREEIKL-YRLQLAQ 597
K+ ++I+ Y + +A+
Sbjct: 930 SKEVQQIQSNYDIAIAE 946
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 55.6 bits (128), Expect = 5e-07
Identities = 64/298 (21%), Positives = 129/298 (43%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 141 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 200
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 201 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 249
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E QE+D + R ++ L + +
Sbjct: 250 SLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 309
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 310 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 365
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 366 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 419
Score = 45.6 bits (103), Expect = 6e-04
Identities = 59/311 (18%), Positives = 134/311 (43%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E R D+ ++
Sbjct: 228 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQAK 287
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 288 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 347
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 348 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 406
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 407 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 466
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 467 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 520
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 521 ELENELEAEQK 531
>M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2095
Score = 55.6 bits (128), Expect = 5e-07
Identities = 55/296 (18%), Positives = 124/296 (41%), Gaps = 16/296 (5%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E R N R + E ++ E + + + + + F+ +L T + H
Sbjct: 1023 EELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQT 1082
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ Q + K LEE L + V+ D++ +++ V LN +L +
Sbjct: 1083 KTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKR 1142
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + ++ + ELN R++ V DE L T E + K+ + +Q
Sbjct: 1143 RGEQKVQLQ----QAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAE 1198
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
E + + ++++ +N++ +R + LQ+ + +L + ++E + QL +
Sbjct: 1199 EFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCE---TNIKELERQLQQ 1255
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ---HKLEINVLEEKQREEIKLYRLQL 595
+M+ ++ N+ ++ ++E++ K E+ L++K ++IK + QL
Sbjct: 1256 YREQMQQGQHMEANHY-----QKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 1306
Score = 50.8 bits (116), Expect = 1e-05
Identities = 59/295 (20%), Positives = 132/295 (44%), Gaps = 22/295 (7%)
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
D A+K S EL + L+ ++ Q ++ K ++ EL+++N +E+
Sbjct: 874 DQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREV 933
Query: 399 DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT 458
D + + + + L + + + E E+ KS+ L ++ + +++ L
Sbjct: 934 DRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSD--HLKEQFEKSHEQLL--- 988
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFL---DNEVKTLRQHLELQK 514
+++ K N ++ + + ++L EK N+C+E+LK K + L +NE K + Q ++ +
Sbjct: 989 --QNIKAEKENNDKIQ--RLNEEL-EKSNECAEMLKQKVEELTRQNNETKLMMQRIQAES 1043
Query: 515 NELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ Q +Q +A+ + F++QL + + +++ F ++I +EE
Sbjct: 1044 ENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD-----FQRKIKCLEED 1098
Query: 573 HKLEINVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
N++ E KQ+ + + +Q + + E + +RRGE +L A
Sbjct: 1099 LAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQA 1153
Score = 50.4 bits (115), Expect = 2e-05
Identities = 65/318 (20%), Positives = 121/318 (38%), Gaps = 14/318 (4%)
Query: 254 IIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSL 313
I +L EE K C M+ + M+ +A+ I ++ + +L
Sbjct: 1001 IQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEAL 1060
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ----L 369
D + L + D Q+K E +L K+ +L +++ KC Q +
Sbjct: 1061 KIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIII 1120
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
QN KK + LN EL N K + ++ V LN +L L +E
Sbjct: 1121 QNTKKEVRN-LNAEL---NASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEE 1176
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ H E K QS + + L++SKV E + I Q +
Sbjct: 1177 QMTHRKMVLFQEESGKFKQSAEE---FRKKMEKLMESKVITEND-ISGIRLDFVSLQQEN 1232
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
S + + +K L + L+ + +++ + +E K Q+ +++L +RE+EN
Sbjct: 1233 SRAQENAKLCETNIKELERQLQQYREQMQ--QGQHMEANHYQKCQKLEDELIAQKREVEN 1290
Query: 550 DARLKENNIVDSFNKQIL 567
+ + I + ++ +L
Sbjct: 1291 LKQKMDQQIKEHEHQLVL 1308
Score = 42.7 bits (96), Expect = 0.004
Identities = 63/304 (20%), Positives = 125/304 (41%), Gaps = 12/304 (3%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKK-TSHFESELYKTLD 357
IS++R LRL N DR + R LE+ FR+ + KK + +L +
Sbjct: 189 ISEVRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITN 248
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
++ + + +L +LN L N+N + S ID LK + V++ N Q +
Sbjct: 249 KCEEFFSQA-AASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLK-TVNLVLK-NTQAAE 305
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV 477
+ L E E+ A + K+NI L ++ E Q L+ ++ + ++
Sbjct: 306 ALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDE 365
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE--DAVLAKLQE 535
+ + E+ +K D L + + ++ + +L+ K L+ L +
Sbjct: 366 MFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLE-GIGKSLKYYRDTYHPLDD 424
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE----QHKL-EINVLEEKQREEIKL 590
+ +Q++ +R+++ + + N+Q + + E Q K+ E E+ +K
Sbjct: 425 WIQQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKD 484
Query: 591 YRLQ 594
Y LQ
Sbjct: 485 YELQ 488
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/358 (18%), Positives = 150/358 (41%), Gaps = 22/358 (6%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTN-SLD--RAED---RHRKALEKMICEVENFRVVADD 340
V ++ + ++AA ++LR+ + + SL RAE ++R+ LE ++ E E +
Sbjct: 603 VEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELER 662
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ T E++ + +++++ ++ +++LE+ L + ++N + K+K ++
Sbjct: 663 VRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEE 722
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
L+ D ++L +K +E+ L +K + ++ + E +E
Sbjct: 723 LRRKRDN----EEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRE 778
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL---DNEVKTLRQHLELQKNEL 517
L + + S AV Q + + E+ ++ D L + + + + L + N L
Sbjct: 779 NALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNAL 838
Query: 518 KCHYQKQLEDAVLA--KLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
+ E A L KL E L + E+E +++ +++Q+ + Q
Sbjct: 839 QLEKTSSEEKARLLKDKLDETNNTLRCLKLELE-----RKDQAEKGYSQQLRELGRQLNQ 893
Query: 576 EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRH 633
EE +E L +++ E L K + Q R + R HA + + +H
Sbjct: 894 TTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQ--REVDRITRAHAVAEKNIQH 949
>L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antigen
protein.
Length = 2649
Score = 55.6 bits (128), Expect = 5e-07
Identities = 55/296 (18%), Positives = 124/296 (41%), Gaps = 16/296 (5%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E R N R + E ++ E + + + + + F+ +L T + H
Sbjct: 1577 EELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQT 1636
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ Q + K LEE L + V+ D++ +++ V LN +L +
Sbjct: 1637 KTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKR 1696
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + ++ + ELN R++ V DE L T E + K+ + +Q
Sbjct: 1697 RGEQKVQLQ----QAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAE 1752
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
E + + ++++ +N++ +R + LQ+ + +L + ++E + QL +
Sbjct: 1753 EFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCE---TNIKELERQLQQ 1809
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ---HKLEINVLEEKQREEIKLYRLQL 595
+M+ ++ N+ ++ ++E++ K E+ L++K ++IK + QL
Sbjct: 1810 YREQMQQGQHMEANHY-----QKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 1860
Score = 50.8 bits (116), Expect = 1e-05
Identities = 59/295 (20%), Positives = 132/295 (44%), Gaps = 22/295 (7%)
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
D A+K S EL + L+ ++ Q ++ K ++ EL+++N +E+
Sbjct: 1428 DQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREV 1487
Query: 399 DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT 458
D + + + + L + + + E E+ KS+ L ++ + +++ L
Sbjct: 1488 DRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSD--HLKEQFEKSHEQLL--- 1542
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFL---DNEVKTLRQHLELQK 514
+++ K N ++ + + ++L EK N+C+E+LK K + L +NE K + Q ++ +
Sbjct: 1543 --QNIKAEKENNDKIQ--RLNEEL-EKSNECAEMLKQKVEELTRQNNETKLMMQRIQAES 1597
Query: 515 NELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ Q +Q +A+ + F++QL + + +++ F ++I +EE
Sbjct: 1598 ENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD-----FQRKIKCLEED 1652
Query: 573 HKLEINVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
N++ E KQ+ + + +Q + + E + +RRGE +L A
Sbjct: 1653 LAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQA 1707
Score = 50.4 bits (115), Expect = 2e-05
Identities = 65/318 (20%), Positives = 121/318 (38%), Gaps = 14/318 (4%)
Query: 254 IIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSL 313
I +L EE K C M+ + M+ +A+ I ++ + +L
Sbjct: 1555 IQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEAL 1614
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ----L 369
D + L + D Q+K E +L K+ +L +++ KC Q +
Sbjct: 1615 KIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIII 1674
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
QN KK + LN EL N K + ++ V LN +L L +E
Sbjct: 1675 QNTKKEVRN-LNAEL---NASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEE 1730
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ H E K QS + + L++SKV E + I Q +
Sbjct: 1731 QMTHRKMVLFQEESGKFKQSAEE---FRKKMEKLMESKVITEND-ISGIRLDFVSLQQEN 1786
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
S + + +K L + L+ + +++ + +E K Q+ +++L +RE+EN
Sbjct: 1787 SRAQENAKLCETNIKELERQLQQYREQMQ--QGQHMEANHYQKCQKLEDELIAQKREVEN 1844
Query: 550 DARLKENNIVDSFNKQIL 567
+ + I + ++ +L
Sbjct: 1845 LKQKMDQQIKEHEHQLVL 1862
Score = 42.7 bits (96), Expect = 0.004
Identities = 63/304 (20%), Positives = 125/304 (41%), Gaps = 12/304 (3%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKK-TSHFESELYKTLD 357
IS++R LRL N DR + R LE+ FR+ + KK + +L +
Sbjct: 743 ISEVRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITN 802
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
++ + + +L +LN L N+N + S ID LK + V++ N Q +
Sbjct: 803 KCEEFFSQA-AASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLK-TVNLVLK-NTQAAE 859
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV 477
+ L E E+ A + K+NI L ++ E Q L+ ++ + ++
Sbjct: 860 ALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDE 919
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE--DAVLAKLQE 535
+ + E+ +K D L + + ++ + +L+ K L+ L +
Sbjct: 920 MFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLE-GIGKSLKYYRDTYHPLDD 978
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE----QHKL-EINVLEEKQREEIKL 590
+ +Q++ +R+++ + + N+Q + + E Q K+ E E+ +K
Sbjct: 979 WIQQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKD 1038
Query: 591 YRLQ 594
Y LQ
Sbjct: 1039 YELQ 1042
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/358 (18%), Positives = 150/358 (41%), Gaps = 22/358 (6%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTN-SLD--RAED---RHRKALEKMICEVENFRVVADD 340
V ++ + ++AA ++LR+ + + SL RAE ++R+ LE ++ E E +
Sbjct: 1157 VEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELER 1216
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ T E++ + +++++ ++ +++LE+ L + ++N + K+K ++
Sbjct: 1217 VRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEE 1276
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
L+ D ++L +K +E+ L +K + ++ + E +E
Sbjct: 1277 LRRKRDN----EEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRE 1332
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL---DNEVKTLRQHLELQKNEL 517
L + + S AV Q + + E+ ++ D L + + + + L + N L
Sbjct: 1333 NALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNAL 1392
Query: 518 KCHYQKQLEDAVLA--KLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
+ E A L KL E L + E+E +++ +++Q+ + Q
Sbjct: 1393 QLEKTSSEEKARLLKDKLDETNNTLRCLKLELE-----RKDQAEKGYSQQLRELGRQLNQ 1447
Query: 576 EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRH 633
EE +E L +++ E L K + Q R + R HA + + +H
Sbjct: 1448 TTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQ--REVDRITRAHAVAEKNIQH 1503
>AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein.
Length = 2649
Score = 55.6 bits (128), Expect = 5e-07
Identities = 55/296 (18%), Positives = 124/296 (41%), Gaps = 16/296 (5%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E R N R + E ++ E + + + + + F+ +L T + H
Sbjct: 1577 EELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQT 1636
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ Q + K LEE L + V+ D++ +++ V LN +L +
Sbjct: 1637 KTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKR 1696
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+K + ++ + ELN R++ V DE L T E + K+ + +Q
Sbjct: 1697 RGEQKVQLQ----QAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAE 1752
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLR-QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
E + + ++++ +N++ +R + LQ+ + +L + ++E + QL +
Sbjct: 1753 EFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKLCE---TNIKELERQLQQ 1809
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQ---HKLEINVLEEKQREEIKLYRLQL 595
+M+ ++ N+ ++ ++E++ K E+ L++K ++IK + QL
Sbjct: 1810 YREQMQQGQHMEANHY-----QKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 1860
Score = 50.8 bits (116), Expect = 1e-05
Identities = 59/295 (20%), Positives = 132/295 (44%), Gaps = 22/295 (7%)
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
D A+K S EL + L+ ++ Q ++ K ++ EL+++N +E+
Sbjct: 1428 DQAEKGYSQQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREV 1487
Query: 399 DVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT 458
D + + + + L + + + E E+ KS+ L ++ + +++ L
Sbjct: 1488 DRITRAHAVAEKNIQHLNSQIHSFRDEKELERLQICQRKSD--HLKEQFEKSHEQLL--- 1542
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFL---DNEVKTLRQHLELQK 514
+++ K N ++ + + ++L EK N+C+E+LK K + L +NE K + Q ++ +
Sbjct: 1543 --QNIKAEKENNDKIQ--RLNEEL-EKSNECAEMLKQKVEELTRQNNETKLMMQRIQAES 1597
Query: 515 NELKCHYQ--KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ Q +Q +A+ + F++QL + + +++ F ++I +EE
Sbjct: 1598 ENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQD-----FQRKIKCLEED 1652
Query: 573 HKLEINVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
N++ E KQ+ + + +Q + + E + +RRGE +L A
Sbjct: 1653 LAKSQNLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQQA 1707
Score = 50.4 bits (115), Expect = 2e-05
Identities = 65/318 (20%), Positives = 121/318 (38%), Gaps = 14/318 (4%)
Query: 254 IIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSL 313
I +L EE K C M+ + M+ +A+ I ++ + +L
Sbjct: 1555 IQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEAL 1614
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ----L 369
D + L + D Q+K E +L K+ +L +++ KC Q +
Sbjct: 1615 KIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIII 1674
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
QN KK + LN EL N K + ++ V LN +L L +E
Sbjct: 1675 QNTKKEVRN-LNAEL---NASKEEKRRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEE 1730
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ H E K QS + + L++SKV E + I Q +
Sbjct: 1731 QMTHRKMVLFQEESGKFKQSAEE---FRKKMEKLMESKVITEND-ISGIRLDFVSLQQEN 1786
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
S + + +K L + L+ + +++ + +E K Q+ +++L +RE+EN
Sbjct: 1787 SRAQENAKLCETNIKELERQLQQYREQMQ--QGQHMEANHYQKCQKLEDELIAQKREVEN 1844
Query: 550 DARLKENNIVDSFNKQIL 567
+ + I + ++ +L
Sbjct: 1845 LKQKMDQQIKEHEHQLVL 1862
Score = 42.7 bits (96), Expect = 0.004
Identities = 63/304 (20%), Positives = 125/304 (41%), Gaps = 12/304 (3%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKK-TSHFESELYKTLD 357
IS++R LRL N DR + R LE+ FR+ + KK + +L +
Sbjct: 743 ISEVRNIRLRLENCEDRLIRQIRTPLERDDLHESVFRITEQEKLKKELERLKDDLGTITN 802
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
++ + + +L +LN L N+N + S ID LK + V++ N Q +
Sbjct: 803 KCEEFFSQA-AASSSVPTLRSELNVVLQNMNQVYSMSSTYIDKLK-TVNLVLK-NTQAAE 859
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV 477
+ L E E+ A + K+NI L ++ E Q L+ ++ + ++
Sbjct: 860 ALVKLYETKLCEEEAVIADKNNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDE 919
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE--DAVLAKLQE 535
+ + E+ +K D L + + ++ + +L+ K L+ L +
Sbjct: 920 MFKTYKERDLDFDWHKEKADQLVERWQNVHVQIDNRLRDLE-GIGKSLKYYRDTYHPLDD 978
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE----QHKL-EINVLEEKQREEIKL 590
+ +Q++ +R+++ + + N+Q + + E Q K+ E E+ +K
Sbjct: 979 WIQQVETTQRKIQENQPENSKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKD 1038
Query: 591 YRLQ 594
Y LQ
Sbjct: 1039 YELQ 1042
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/358 (18%), Positives = 150/358 (41%), Gaps = 22/358 (6%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTN-SLD--RAED---RHRKALEKMICEVENFRVVADD 340
V ++ + ++AA ++LR+ + + SL RAE ++R+ LE ++ E E +
Sbjct: 1157 VEEELPKVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELER 1216
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ T E++ + +++++ ++ +++LE+ L + ++N + K+K ++
Sbjct: 1217 VRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKNKLMEE 1276
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
L+ D ++L +K +E+ L +K + ++ + E +E
Sbjct: 1277 LRRKRDN----EEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCRE 1332
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFL---DNEVKTLRQHLELQKNEL 517
L + + S AV Q + + E+ ++ D L + + + + L + N L
Sbjct: 1333 NALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELTYELNAL 1392
Query: 518 KCHYQKQLEDAVLA--KLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL 575
+ E A L KL E L + E+E +++ +++Q+ + Q
Sbjct: 1393 QLEKTSSEEKARLLKDKLDETNNTLRCLKLELE-----RKDQAEKGYSQQLRELGRQLNQ 1447
Query: 576 EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRH 633
EE +E L +++ E L K + Q R + R HA + + +H
Sbjct: 1448 TTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQ--REVDRITRAHAVAEKNIQH 1503
>AK074847-1|BAC11241.1| 432|Homo sapiens protein ( Homo sapiens
cDNA FLJ90366 fis, clone NT2RP2004141. ).
Length = 432
Score = 55.6 bits (128), Expect = 5e-07
Identities = 36/129 (27%), Positives = 64/129 (49%)
Query: 511 ELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
E Q+ +L+ QLE V +L + QE R + R + ++ +++
Sbjct: 9 ESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQL 68
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
Q K+E+ EE+Q++ + Y L+LA+ ++ L+S + +R E RL A LQAH
Sbjct: 69 AQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAH 128
Query: 631 WRHALRILA 639
W A ++L+
Sbjct: 129 WDEANQLLS 137
>AY639646-1|AAX19141.1| 572|Homo sapiens prefoldin subunit 6-like
protein protein.
Length = 572
Score = 55.2 bits (127), Expect = 7e-07
Identities = 51/222 (22%), Positives = 107/222 (48%), Gaps = 21/222 (9%)
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT--QERDLLKSKVNEERSRCAVI 478
NL+E L +EK + I +L ++++ + L T E+ L+ K+ E A +
Sbjct: 126 NLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKV 185
Query: 479 EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQ------KQLE--- 526
+QQ E+Q + + + D L +V+TL+ LE+ ++ + Q KQLE
Sbjct: 186 KQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEK 245
Query: 527 ---DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH---KLEINVL 580
D + QE E+L + ++E E R + ++ N + E+H K+++ +
Sbjct: 246 RKYDEHVKSNQELSEKLSKLQQEKE-ALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKV 304
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
+ + E++L ++ Q +++G+L+ K+E ++ + + A+
Sbjct: 305 KYRLTNEVELRDKRINQFEDEIGILQHKIEKEKAIQDQITAQ 346
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/284 (20%), Positives = 120/284 (42%), Gaps = 19/284 (6%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQ 379
++ L +M C + R+ +A K E Y + + + +K +LQ EK++L E+
Sbjct: 216 KENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREE 275
Query: 380 -------LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN----KQLTDCVKNLEEALEK 428
LN + N N + ++ +K + L Q D + L+ +EK
Sbjct: 276 YLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFEDEIGILQHKIEK 335
Query: 429 EKFAHDS-TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
EK D T N T L ++ + + ++ + Q K ++ +SR ++++ + Q
Sbjct: 336 EKAIQDQITAQNDTLLLEK-RKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQE 394
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
+ ++ FL+ ++++ H+ +N + K LA L ++Q + E+
Sbjct: 395 NSLRLTQQIGFLERIIRSI--HIRRGENLKEFPVPKWWHRGKLASLPPTKKQKEIYSTEV 452
Query: 548 --ENDARLK-ENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
N+A L+ E+ V ++ E+ ++LE + EI
Sbjct: 453 FTSNNAELQHEDESVPEATEKWKHSEQMETTISDILESEVVNEI 496
Score = 38.3 bits (85), Expect = 0.085
Identities = 78/378 (20%), Positives = 158/378 (41%), Gaps = 36/378 (9%)
Query: 212 ESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMI 271
E LK+ Q + + +L L L + AE Y RG +D+ K L+ + + I
Sbjct: 20 EKLKYNQQGEVQQLHQNLHRLQILC-NSAENELRYERGQNLDL-KQHNSLLQEGNIKIKI 77
Query: 272 XXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEV 331
+ K K++E L + + ++ EK++ E
Sbjct: 78 ELKHAQQKLLDSTKMCSSLTAEYKHCQ-QKIKELELEVLKHTQSIKSQNNLQ-EKLVQEK 135
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDY--QDKCKQLQNEKKSLEEQLNTELDN--- 386
VAD +K +L + L+ AH D C +EK+ LEE++ N
Sbjct: 136 SK---VADAEEKIL-----DLQRKLEHAHKVCLTDTCI---SEKQQLEEKIKEATQNEAK 184
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
V + ++ +L +N D + R + L D LE +++ ++ + +L
Sbjct: 185 VKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENE 244
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+ DE + QE SK+ +E+ + L E+ + ++L NE K
Sbjct: 245 KRKY-DEHVKSNQELSEKLSKLQQEK-------EALREEYLRLLKLLNVHVRNYNE-KHH 295
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
+Q ++LQK + + + +L D ++ +F++++ + ++E + +++ + + N +
Sbjct: 296 QQKVKLQKVKYRLTNEVELRD---KRINQFEDEIGILQHKIEKEKAIQDQ--ITAQNDTL 350
Query: 567 LRIEEQHKLEINVLEEKQ 584
L E+ KL+ V+E++Q
Sbjct: 351 LL--EKRKLQEQVIEQEQ 366
>AL445669-8|CAH70752.1| 783|Homo sapiens novel protein protein.
Length = 783
Score = 55.2 bits (127), Expect = 7e-07
Identities = 51/222 (22%), Positives = 107/222 (48%), Gaps = 21/222 (9%)
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT--QERDLLKSKVNEERSRCAVI 478
NL+E L +EK + I +L ++++ + L T E+ L+ K+ E A +
Sbjct: 337 NLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKV 396
Query: 479 EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQ------KQLE--- 526
+QQ E+Q + + + D L +V+TL+ LE+ ++ + Q KQLE
Sbjct: 397 KQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEK 456
Query: 527 ---DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH---KLEINVL 580
D + QE E+L + ++E E R + ++ N + E+H K+++ +
Sbjct: 457 RKYDEHVKSNQELSEKLSKLQQEKE-ALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKV 515
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
+ + E++L ++ Q +++G+L+ K+E ++ + + A+
Sbjct: 516 KYRLTNEVELRDKRINQFEDEIGILQHKIEKEKAIQDQITAQ 557
Score = 41.1 bits (92), Expect = 0.012
Identities = 79/378 (20%), Positives = 159/378 (42%), Gaps = 36/378 (9%)
Query: 212 ESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMI 271
E LK+ Q + + +L L L + AE Y RG +D+ K L+ E+ + I
Sbjct: 231 EKLKYNQQGEVQQLHQNLHRLQILC-NSAENELRYERGQNLDL-KQHNSLLQEENIKIKI 288
Query: 272 XXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEV 331
+ K K++E L + + ++ EK++ E
Sbjct: 289 ELKHAQQKLLDSTKMCSSLTAEYKHCQ-QKIKELELEVLKHTQSIKSQNNLQ-EKLVQEK 346
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDY--QDKCKQLQNEKKSLEEQLNTELDN--- 386
VAD +K +L + L+ AH D C +EK+ LEE++ N
Sbjct: 347 SK---VADAEEKIL-----DLQRKLEHAHKVCLTDTCI---SEKQQLEEKIKEATQNEAK 395
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
V + ++ +L +N D + R + L D LE +++ ++ + +L
Sbjct: 396 VKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENE 455
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+ DE + QE SK+ +E+ + L E+ + ++L NE K
Sbjct: 456 KRKY-DEHVKSNQELSEKLSKLQQEK-------EALREEYLRLLKLLNVHVRNYNE-KHH 506
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
+Q ++LQK + + + +L D ++ +F++++ + ++E + +++ + + N +
Sbjct: 507 QQKVKLQKVKYRLTNEVELRD---KRINQFEDEIGILQHKIEKEKAIQDQ--ITAQNDTL 561
Query: 567 LRIEEQHKLEINVLEEKQ 584
L E+ KL+ V+E++Q
Sbjct: 562 LL--EKRKLQEQVIEQEQ 577
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/284 (20%), Positives = 120/284 (42%), Gaps = 19/284 (6%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQ 379
++ L +M C + R+ +A K E Y + + + +K +LQ EK++L E+
Sbjct: 427 KENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREE 486
Query: 380 -------LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN----KQLTDCVKNLEEALEK 428
LN + N N + ++ +K + L Q D + L+ +EK
Sbjct: 487 YLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFEDEIGILQHKIEK 546
Query: 429 EKFAHDS-TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
EK D T N T L ++ + + ++ + Q K ++ +SR ++++ + Q
Sbjct: 547 EKAIQDQITAQNDTLLLEK-RKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQE 605
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
+ ++ FL+ ++++ H+ +N + K LA L ++Q + E+
Sbjct: 606 NSLRLTQQIGFLERIIRSI--HIRRGENLKEFPVPKWWHRGKLASLPPTKKQKEIYSTEV 663
Query: 548 --ENDARLK-ENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
N+A L+ E+ V ++ E+ ++LE + EI
Sbjct: 664 FTSNNAELQHEDESVPEATEKWKHSEQMETTISDILESEVVNEI 707
>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 55.2 bits (127), Expect = 7e-07
Identities = 74/342 (21%), Positives = 159/342 (46%), Gaps = 36/342 (10%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENF-RVVADDAQKKTSHFESELYKTLD 357
I KL+ + +R +++ K + ++ E E + + ++ Q+K + ++ ++
Sbjct: 1085 IEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVE 1144
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQLT 416
+ + + K ++E L T L+ V S+ K E D+L E +++L + L
Sbjct: 1145 GKRALSELTQGVTCYKAKIKE-LETILETQKVECSHSAKLEQDIL-EKESIILKLERNLK 1202
Query: 417 -------DCVKNLEEALEKE-KFAHDSTK--SNITELNKRIQSVNDETLLLTQERDLLKS 466
D VKN ++ KE K + T+ +N+ ++ +Q +E QE + LK
Sbjct: 1203 EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKE 1262
Query: 467 KVNEERSRC--------------AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-E 511
+++ +R A ++++L + + Q +V K+ + +E K LR + E
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1322
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQI 566
L+K + +C + ++ + +L+E ++++ A ++ E D +KE I D +
Sbjct: 1323 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMT 1380
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
L +EQ ++E + + E + EE++ +L + EK LE+K
Sbjct: 1381 LEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETK 1422
Score = 54.8 bits (126), Expect = 9e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 1174 KVECSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1230
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 1231 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1286
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 1287 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 1334
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 1335 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 1389
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 1390 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 1425
Score = 45.2 bits (102), Expect = 7e-04
Identities = 94/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 823 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 882
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 883 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 936
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 937 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 993
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 994 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 1049
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 1050 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 1108
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 1109 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 1168
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E C + +LE +L K + +L+R +E + + N D
Sbjct: 1169 ILETQKVE--CSHSAKLEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 1217
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 1218 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1267
Score = 32.3 bits (70), Expect = 5.6
Identities = 54/257 (21%), Positives = 114/257 (44%), Gaps = 29/257 (11%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K + ++EL KT +++ K+ +NE SL ++L T + + I+++ +
Sbjct: 716 KFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQ 775
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
DT+ +NL+ +E +D ++ +N ++ + +ET+ + ++
Sbjct: 776 KEDTINEF--------QNLKSHMENTFKCNDKADTSSLIINNKL--ICNETVEVPKDS-- 823
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KSK+ ER R E Q E + + +++ K+ E++ N
Sbjct: 824 -KSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKS----EEVRPN------IA 872
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLE 581
++ED + LQE E L +EN+ + E NKQI+ +++ L + N+
Sbjct: 873 EIED--IRVLQENNEGLRAFLLTIENELK-NEKEEKAELNKQIVHFQQELSLSEKKNLTL 929
Query: 582 EKQREEIKL-YRLQLAQ 597
K+ ++I+ Y + +A+
Sbjct: 930 SKEVQQIQSNYDIAIAE 946
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 55.2 bits (127), Expect = 7e-07
Identities = 74/342 (21%), Positives = 159/342 (46%), Gaps = 36/342 (10%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENF-RVVADDAQKKTSHFESELYKTLD 357
I KL+ + +R +++ K + ++ E E + + ++ Q+K + ++ ++
Sbjct: 1045 IEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVE 1104
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQLT 416
+ + + K ++E L T L+ V S+ K E D+L E +++L + L
Sbjct: 1105 GKRALSELTQGVTCYKAKIKE-LETILETQKVECSHSAKLEQDIL-EKESIILKLERNLK 1162
Query: 417 -------DCVKNLEEALEKE-KFAHDSTK--SNITELNKRIQSVNDETLLLTQERDLLKS 466
D VKN ++ KE K + T+ +N+ ++ +Q +E QE + LK
Sbjct: 1163 EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKE 1222
Query: 467 KVNEERSRC--------------AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-E 511
+++ +R A ++++L + + Q +V K+ + +E K LR + E
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQI 566
L+K + +C + ++ + +L+E ++++ A ++ E D +KE I D +
Sbjct: 1283 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMT 1340
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
L +EQ ++E + + E + EE++ +L + EK LE+K
Sbjct: 1341 LEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETK 1382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 1134 KVECSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1190
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 1191 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1246
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 1247 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 1294
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 1295 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 1349
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 1350 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 1385
Score = 45.2 bits (102), Expect = 7e-04
Identities = 94/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 783 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 842
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 843 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 896
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 897 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 953
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 954 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 1009
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 1010 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 1068
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 1069 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 1128
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E C + +LE +L K + +L+R +E + + N D
Sbjct: 1129 ILETQKVE--CSHSAKLEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 1177
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 1178 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1227
Score = 32.7 bits (71), Expect = 4.2
Identities = 61/282 (21%), Positives = 124/282 (43%), Gaps = 32/282 (11%)
Query: 321 RKALEKMIC--EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE 378
R+ K IC +VE A + K + ++EL KT +++ K+ +NE SL +
Sbjct: 652 REEAAKDICATKVETEEATAC-LELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQ 710
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
+L T + + I+++ + DT+ +NL+ +E +D +
Sbjct: 711 ELETSNKKIITQNQRIKELINIIDQKEDTINEF--------QNLKSHMENTFKCNDKADT 762
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF 498
+ +N ++ + +ET+ + ++ KSK+ ER R E Q E + +
Sbjct: 763 SSLIINNKL--ICNETVEVPKDS---KSKICSERKRVNENELQQDEPPAKKGSIHVSSAI 817
Query: 499 LDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+++ K+ E++ N ++ED + LQE E L +EN+ + E
Sbjct: 818 TEDQKKS----EEVRPN------IAEIED--IRVLQENNEGLRAFLLTIENELK-NEKEE 864
Query: 559 VDSFNKQILRIEEQHKL--EINVLEEKQREEIKL-YRLQLAQ 597
NKQI+ +++ L + N+ K+ ++I+ Y + +A+
Sbjct: 865 KAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAE 906
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 55.2 bits (127), Expect = 7e-07
Identities = 74/342 (21%), Positives = 159/342 (46%), Gaps = 36/342 (10%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENF-RVVADDAQKKTSHFESELYKTLD 357
I KL+ + +R +++ K + ++ E E + + ++ Q+K + ++ ++
Sbjct: 1045 IEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVE 1104
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQLT 416
+ + + K ++E L T L+ V S+ K E D+L E +++L + L
Sbjct: 1105 GKRALSELTQGVTCYKAKIKE-LETILETQKVECSHSAKLEQDIL-EKESIILKLERNLK 1162
Query: 417 -------DCVKNLEEALEKE-KFAHDSTK--SNITELNKRIQSVNDETLLLTQERDLLKS 466
D VKN ++ KE K + T+ +N+ ++ +Q +E QE + LK
Sbjct: 1163 EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKE 1222
Query: 467 KVNEERSRC--------------AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-E 511
+++ +R A ++++L + + Q +V K+ + +E K LR + E
Sbjct: 1223 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1282
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQI 566
L+K + +C + ++ + +L+E ++++ A ++ E D +KE I D +
Sbjct: 1283 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMT 1340
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
L +EQ ++E + + E + EE++ +L + EK LE+K
Sbjct: 1341 LEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETK 1382
Score = 54.8 bits (126), Expect = 9e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 1134 KVECSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1190
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 1191 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1246
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 1247 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 1294
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 1295 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 1349
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 1350 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 1385
Score = 45.2 bits (102), Expect = 7e-04
Identities = 94/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 783 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 842
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 843 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 896
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 897 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 953
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 954 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 1009
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 1010 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 1068
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 1069 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 1128
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E C + +LE +L K + +L+R +E + + N D
Sbjct: 1129 ILETQKVE--CSHSAKLEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 1177
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 1178 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1227
Score = 32.7 bits (71), Expect = 4.2
Identities = 61/282 (21%), Positives = 124/282 (43%), Gaps = 32/282 (11%)
Query: 321 RKALEKMIC--EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE 378
R+ K IC +VE A + K + ++EL KT +++ K+ +NE SL +
Sbjct: 652 REEAAKDICATKVETEEATAC-LELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQ 710
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
+L T + + I+++ + DT+ +NL+ +E +D +
Sbjct: 711 ELETSNKKIITQNQRIKELINIIDQKEDTINEF--------QNLKSHMENTFKCNDKADT 762
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF 498
+ +N ++ + +ET+ + ++ KSK+ ER R E Q E + +
Sbjct: 763 SSLIINNKL--ICNETVEVPKDS---KSKICSERKRVNENELQQDEPPAKKGSIHVSSAI 817
Query: 499 LDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
+++ K+ E++ N ++ED + LQE E L +EN+ + E
Sbjct: 818 TEDQKKS----EEVRPN------IAEIED--IRVLQENNEGLRAFLLTIENELK-NEKEE 864
Query: 559 VDSFNKQILRIEEQHKL--EINVLEEKQREEIKL-YRLQLAQ 597
NKQI+ +++ L + N+ K+ ++I+ Y + +A+
Sbjct: 865 KAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAE 906
>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 55.2 bits (127), Expect = 7e-07
Identities = 74/342 (21%), Positives = 159/342 (46%), Gaps = 36/342 (10%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENF-RVVADDAQKKTSHFESELYKTLD 357
I KL+ + +R +++ K + ++ E E + + ++ Q+K + ++ ++
Sbjct: 1085 IEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVE 1144
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQLT 416
+ + + K ++E L T L+ V S+ K E D+L E +++L + L
Sbjct: 1145 GKRALSELTQGVTCYKAKIKE-LETILETQKVECSHSAKLEQDIL-EKESIILKLERNLK 1202
Query: 417 -------DCVKNLEEALEKE-KFAHDSTK--SNITELNKRIQSVNDETLLLTQERDLLKS 466
D VKN ++ KE K + T+ +N+ ++ +Q +E QE + LK
Sbjct: 1203 EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKE 1262
Query: 467 KVNEERSRC--------------AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-E 511
+++ +R A ++++L + + Q +V K+ + +E K LR + E
Sbjct: 1263 ELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE 1322
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEF--QEQLDRAEREMEN---DARLKENNIVDSFNKQI 566
L+K + +C + ++ + +L+E ++++ A ++ E D +KE I D +
Sbjct: 1323 LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDM--RMT 1380
Query: 567 LRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
L +EQ ++E + + E + EE++ +L + EK LE+K
Sbjct: 1381 LEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETK 1422
Score = 54.8 bits (126), Expect = 9e-07
Identities = 60/276 (21%), Positives = 127/276 (46%), Gaps = 28/276 (10%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
+ E H LE+ I E E+ + ++ F+ L ++ D K +L+ E
Sbjct: 1174 KVECSHSAKLEQDILEKESIIL---KLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEIT 1230
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
QL L ++ +L K++E + ++ + + + +NL+ L++++ +
Sbjct: 1231 ----QLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYA 1286
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K +T+ K+I+ V E ++ E LL+ K+NE L +K+NQCS+ L
Sbjct: 1287 DLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINE-----------LEKKKNQCSQEL- 1334
Query: 495 KCDFLDNEVKTLRQHLELQK-NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
D ++ L++ L QK E Y++ +D L ++ E + R E + ++
Sbjct: 1335 --DMKQRTIQQLKEQLNNQKVEEAIQQYERACKD--LNVKEKIIEDM-RMTLEEQEQTQV 1389
Query: 554 KENNIVDSFNKQILRIE---EQHKLEINVLEEKQRE 586
+++ ++++ +++ R+ E+ K + N LE K +
Sbjct: 1390 EQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQ 1425
Score = 45.2 bits (102), Expect = 7e-04
Identities = 94/478 (19%), Positives = 194/478 (40%), Gaps = 45/478 (9%)
Query: 161 SSNKIYDRASRVLE-QYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQN 219
S +KI RV E + + K G+ SA + + K E+RP E ++ +Q
Sbjct: 823 SKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQE 882
Query: 220 KYIDTIDSDLLSL-SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXX 278
+ + + LL++ +EL +K E+ N+ I+ ++E E +
Sbjct: 883 NN-EGLRAFLLTIENELKNEKEEKAE-LNK----QIVHFQQELSLSEKKNLTLSKEVQQI 936
Query: 279 XXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD---RAEDRHRKALEKMICEVENFR 335
+ V ++K+ + E ++L+N ++ R+ + ++ M +++ R
Sbjct: 937 QSNYDIAIAELHVQKSKN---QEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELR 993
Query: 336 VVADDAQKKTSHFESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK 394
+ D+ + S+ + L DL++ +D Q + + ++ ++ + N+
Sbjct: 994 TL--DSVSQISNID--LLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNR 1049
Query: 395 DKE----IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSV 450
+ I+ + E +++ + + + ++ LE+ +EK + K L ++ +
Sbjct: 1050 ENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK-EHK 1108
Query: 451 NDETLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
N + LL +E + LK ++ E+ V Q + E + SE+ + ++K L
Sbjct: 1109 NQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELET 1168
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
LE QK E C + +LE +L K + +L+R +E + + N D
Sbjct: 1169 ILETQKVE--CSHSAKLEQDILEK-ESIILKLERNLKEFQEHLQDSVKNTKD-------- 1217
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+NV E K +EEI L L L E + E R+ + L A+
Sbjct: 1218 --------LNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSAS 1267
Score = 32.3 bits (70), Expect = 5.6
Identities = 54/257 (21%), Positives = 114/257 (44%), Gaps = 29/257 (11%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K + ++EL KT +++ K+ +NE SL ++L T + + I+++ +
Sbjct: 716 KFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQRIKELINIIDQ 775
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
DT+ +NL+ +E +D ++ +N ++ + +ET+ + ++
Sbjct: 776 KEDTINEF--------QNLKSHMENTFKCNDKADTSSLIINNKL--ICNETVEVPKDS-- 823
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQK 523
KSK+ ER R E Q E + + +++ K+ E++ N
Sbjct: 824 -KSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKS----EEVRPN------IA 872
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLE 581
++ED + LQE E L +EN+ + E NKQI+ +++ L + N+
Sbjct: 873 EIED--IRVLQENNEGLRAFLLTIENELK-NEKEEKAELNKQIVHFQQELSLSEKKNLTL 929
Query: 582 EKQREEIKL-YRLQLAQ 597
K+ ++I+ Y + +A+
Sbjct: 930 SKEVQQIQSNYDIAIAE 946
>AL138788-1|CAI22439.1| 783|Homo sapiens novel protein protein.
Length = 783
Score = 55.2 bits (127), Expect = 7e-07
Identities = 51/222 (22%), Positives = 107/222 (48%), Gaps = 21/222 (9%)
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT--QERDLLKSKVNEERSRCAVI 478
NL+E L +EK + I +L ++++ + L T E+ L+ K+ E A +
Sbjct: 337 NLQEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKV 396
Query: 479 EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQ------KQLE--- 526
+QQ E+Q + + + D L +V+TL+ LE+ ++ + Q KQLE
Sbjct: 397 KQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEK 456
Query: 527 ---DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH---KLEINVL 580
D + QE E+L + ++E E R + ++ N + E+H K+++ +
Sbjct: 457 RKYDEHVKSNQELSEKLSKLQQEKE-ALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKV 515
Query: 581 EEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
+ + E++L ++ Q +++G+L+ K+E ++ + + A+
Sbjct: 516 KYRLTNEVELRDKRINQFEDEIGILQHKIEKEKAIQDQITAQ 557
Score = 41.1 bits (92), Expect = 0.012
Identities = 79/378 (20%), Positives = 159/378 (42%), Gaps = 36/378 (9%)
Query: 212 ESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMI 271
E LK+ Q + + +L L L + AE Y RG +D+ K L+ E+ + I
Sbjct: 231 EKLKYNQQGEVQQLHQNLHRLQILC-NSAENELRYERGQNLDL-KQHNSLLQEENIKIKI 288
Query: 272 XXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEV 331
+ K K++E L + + ++ EK++ E
Sbjct: 289 ELKHAQQKLLDSTKMCSSLTAEYKHCQ-QKIKELELEVLKHTQSIKSQNNLQ-EKLVQEK 346
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDY--QDKCKQLQNEKKSLEEQLNTELDN--- 386
VAD +K +L + L+ AH D C +EK+ LEE++ N
Sbjct: 347 SK---VADAEEKIL-----DLQRKLEHAHKVCLTDTCI---SEKQQLEEKIKEATQNEAK 395
Query: 387 VNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKR 446
V + ++ +L +N D + R + L D LE +++ ++ + +L
Sbjct: 396 VKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENE 455
Query: 447 IQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL 506
+ DE + QE SK+ +E+ + L E+ + ++L NE K
Sbjct: 456 KRKY-DEHVKSNQELSEKLSKLQQEK-------EALREEYLRLLKLLNVHVRNYNE-KHH 506
Query: 507 RQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
+Q ++LQK + + + +L D ++ +F++++ + ++E + +++ + + N +
Sbjct: 507 QQKVKLQKVKYRLTNEVELRD---KRINQFEDEIGILQHKIEKEKAIQDQ--ITAQNDTL 561
Query: 567 LRIEEQHKLEINVLEEKQ 584
L E+ KL+ V+E++Q
Sbjct: 562 LL--EKRKLQEQVIEQEQ 577
Score = 40.7 bits (91), Expect = 0.016
Identities = 58/284 (20%), Positives = 120/284 (42%), Gaps = 19/284 (6%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQ 379
++ L +M C + R+ +A K E Y + + + +K +LQ EK++L E+
Sbjct: 427 KENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEALREE 486
Query: 380 -------LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN----KQLTDCVKNLEEALEK 428
LN + N N + ++ +K + L Q D + L+ +EK
Sbjct: 487 YLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFEDEIGILQHKIEK 546
Query: 429 EKFAHDS-TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
EK D T N T L ++ + + ++ + Q K ++ +SR ++++ + Q
Sbjct: 547 EKAIQDQITAQNDTLLLEK-RKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQE 605
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
+ ++ FL+ ++++ H+ +N + K LA L ++Q + E+
Sbjct: 606 NSLRLTQQIGFLERIIRSI--HIRRGENLKEFPVPKWWHRGKLASLPPTKKQKEIYSTEV 663
Query: 548 --ENDARLK-ENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
N+A L+ E+ V ++ E+ ++LE + EI
Sbjct: 664 FTSNNAELQHEDESVPEATEKWKHSEQMETTISDILESEVVNEI 707
>AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ45844 fis, clone OCBBF2003518. ).
Length = 600
Score = 55.2 bits (127), Expect = 7e-07
Identities = 72/324 (22%), Positives = 144/324 (44%), Gaps = 25/324 (7%)
Query: 330 EVENFRVVADD----AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD 385
E+EN + V +D A ++ H + + K+ + LQ+ ++ L+ +L+ D
Sbjct: 42 ELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKD 101
Query: 386 NVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK 445
++ KD ++V E R + T EE L+ +K AHD L +
Sbjct: 102 SLK---ETKDALLNVEGELEQE--RQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQ 156
Query: 446 RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKT 505
+ +E L L E D KS +++ +++ + EK KK + L N++
Sbjct: 157 ECSKLREE-LRLQHEEDK-KSAMSQ------LLQLKDREKNAARDSWQKKVEDLLNQISL 208
Query: 506 LRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE-MENDARLKENNIVDSFNK 564
L+Q+LE+Q ++ + Q QL+ + Q ++L+ E + + LKE +++
Sbjct: 209 LKQNLEIQLSQSQTSLQ-QLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTM 267
Query: 565 QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGL-LESKVECQRRRRGETAARL 623
+ + +EQ LE N L++K E++ + ++ E + +E +++ R + +
Sbjct: 268 EEEKEKEQRALE-NHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAM 326
Query: 624 HAALQAHWRH----ALRILAAPHH 643
A L++ H A+ +L HH
Sbjct: 327 LAPLRSELNHQHAAAIDLLRHNHH 350
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 55.2 bits (127), Expect = 7e-07
Identities = 70/331 (21%), Positives = 142/331 (42%), Gaps = 18/331 (5%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D++++ L KM E+ + + D + K HF S+L LD +K E + L+
Sbjct: 554 DQYKEELSKMEKEIMHLK---RDGENKAMHF-SQLDMILDQTKTELEKKTNAVKELEKLQ 609
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
TEL + E+ + +R ++L D ++ + +LE EK+ + K
Sbjct: 610 HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLE-EKYT--TIK 666
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVI---EQQLCEKQNQCSEVLK 494
EL + + DE L + LK + E + R A + + + E + + + +
Sbjct: 667 DLTAELRECKMEIEDEKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKII 726
Query: 495 KCDFL----DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN- 549
K + + E+K + +E ++L+ + ++QL + LQ QE + + ++E+E
Sbjct: 727 KLEGTLEKSELELKECNKQIESLNDKLQ-NAKEQLREKEFIMLQNEQE-ISQLKKEIERT 784
Query: 550 DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
R+KE V +Q + + + +++ RE+++ +LA+A + + ++
Sbjct: 785 QQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQVQNSHTELAEARHQQVQAQREI 844
Query: 610 ECQRRRRGETAARLHAALQAHWRHALRILAA 640
E + E +L AH H L A
Sbjct: 845 E-RLSSELEDMKQLSKEKDAHGNHLAEELGA 874
Score = 42.3 bits (95), Expect = 0.005
Identities = 67/280 (23%), Positives = 129/280 (46%), Gaps = 32/280 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDV 400
++K + S K +L + +K NEK +SLE +NTE + + + K K+I
Sbjct: 268 EEKIVAYSSIAAKNAELEQELMEK-----NEKIRSLETNINTEHEKI-CLAFEKAKKIH- 320
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +K++ ++ LE LEK+ + ++ L + I + + L + +
Sbjct: 321 --------LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI--ICKQHHLESLD 370
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
R L +SK E + ++ L QNQ SE K LD+ ++ ++ L L N+L+ +
Sbjct: 371 RLLTESK-GEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN 429
Query: 521 YQKQLEDAVLAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+K E + K +E Q++L ++ + ++N I+ +Q ++ +Q +
Sbjct: 430 KEK-FEKQLKKKSEEVYCLQKELKIKNHSLQETS--EQNVILQHTLQQQQQMLQQETIRN 486
Query: 578 NVLEEKQRE-EIKLYRL------QLAQAAEKLGLLESKVE 610
LE+ Q + E ++ +L Q +AEKL +E K E
Sbjct: 487 GELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 526
Score = 41.1 bits (92), Expect = 0.012
Identities = 77/376 (20%), Positives = 158/376 (42%), Gaps = 35/376 (9%)
Query: 233 SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVD 292
++L K TG R K+++ + +EE K E + ++ + M +D
Sbjct: 532 ADLKRQKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHFSQLDMILD 589
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVADDAQKKTSHFE 349
+ K + K A L E +AL+K + E++N ++
Sbjct: 590 QTK-TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELR 648
Query: 350 SELYKT-LDLAHDY---QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENY 405
L K L L Y +D +L+ K +E++ EL ++ L ++ E LK+
Sbjct: 649 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDE-KQELLEMDQALKERNWE---LKQRA 704
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------------E 453
V L+ + + +E+ + K + + ++ + E NK+I+S+ND E
Sbjct: 705 AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 764
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
++L E+++ + K ER++ + E + K+ + + +C E L Q L L
Sbjct: 765 FIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQE-QYIATQC----KEAIDLGQKLRLT 819
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +++ + +L +A ++Q Q +++R E+E+ +L + D+ +
Sbjct: 820 REQVQ-NSHTELAEARHQQVQA-QREIERLSSELEDMKQLSKEK--DAHGNHLAEELGAS 875
Query: 574 KLEINVLEEKQREEIK 589
K+ LE + + EIK
Sbjct: 876 KVREAHLEARMQAEIK 891
Score = 39.9 bits (89), Expect = 0.028
Identities = 61/270 (22%), Positives = 124/270 (45%), Gaps = 22/270 (8%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+++D+A +L++ ++T+ LD HR +E+ I ++E ++ K+ +
Sbjct: 687 LEMDQALKERNWELKQRAAQVTH-LDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQ 745
Query: 349 ESELYKTLDLAHDY--QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYD 406
L L A + + + LQNE++ QL E++ + K+ E V+KE
Sbjct: 746 IESLNDKLQNAKEQLREKEFIMLQNEQEI--SQLKKEIERTQQRM--KEME-SVMKEQEQ 800
Query: 407 TVMRLNKQLTDCVKNLEEALEKEKFAHDS---TKSNITELNKRIQSVNDET---LLLTQE 460
+ K+ D + L E+ + +H + + + I+ ++ E L++E
Sbjct: 801 YIATQCKEAIDLGQKLRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKE 860
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ--HLELQKNELK 518
+D + + EE V E L E + Q +KK L EV++L++ H+E+ ++
Sbjct: 861 KDAHGNHLAEELGASKVREAHL-EARMQAE--IKK---LSAEVESLKEAYHMEMISHQEN 914
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
K D+ + +Q+ EQL++A+ E+E
Sbjct: 915 HAKWKISADSQKSSVQQLNEQLEKAKLELE 944
Score = 39.1 bits (87), Expect = 0.049
Identities = 67/283 (23%), Positives = 126/283 (44%), Gaps = 35/283 (12%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQL---------NTELDNVNVMLSNKDKEIDVLKENYDTV 408
L + KC QL +K LEE++ N EL+ L K+++I L+ N +T
Sbjct: 249 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQ---ELMEKNEKIRSLETNINTE 305
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKS 466
+ K + LE+ K + +L K+ Q ++ T+ + Q+ + K
Sbjct: 306 HEKICLAFEKAKKIH--LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQ 363
Query: 467 KVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHY 521
E R + +K+N + E LK +E V+ L LE+ K EL H
Sbjct: 364 HHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 423
Query: 522 QKQLEDAVLAKLQEFQEQLDRAERE---MENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
QLE ++F++QL + E ++ + ++K +++ ++ + ++ QH L+
Sbjct: 424 -NQLE----GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL---QHTLQ-Q 474
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAA 621
+ Q+E I+ L+ Q KL SK+E + +++ E++A
Sbjct: 475 QQQMLQQETIRNGELEDTQT--KLEKQVSKLEQELQKQRESSA 515
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 55.2 bits (127), Expect = 7e-07
Identities = 96/485 (19%), Positives = 191/485 (39%), Gaps = 45/485 (9%)
Query: 170 SRVLEQYKASYSKNKPGATDSYSASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDL 229
+R +E + K + A + +R E + +K ++ + +++++
Sbjct: 1331 TRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEM 1390
Query: 230 LSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAM 289
+ W K E D D K RL+ E EAM + +
Sbjct: 1391 VQ----WRMKYENNVIQRTEDLEDAKKELAIRLQ-EAAEAMGVANARNASLERARHQLQL 1445
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++ A + + K+R A RL D+ + + KAL + E + + D +QK+
Sbjct: 1446 ELGDAL-SDLGKVRSAAARL----DQKQLQSGKALADWKQKHEESQALLDASQKEVQALS 1500
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN-------------TELDNVNVMLSNKDK 396
+EL K + + + L+ E K+L+E+++ TE++ V ++ +
Sbjct: 1501 TELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKT 1560
Query: 397 EIDV--------LKENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRI 447
E+ V L+ N ++ +L + LE L EK++ + + ++ +
Sbjct: 1561 EVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDS-L 1619
Query: 448 QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR 507
QS D E LK K+ E+ + +E QL Q SE K L ++K L+
Sbjct: 1620 QSSLDSEAKSRIEVTRLKKKMEEDLNE---MELQLSCANRQVSEATKSLGQLQIQIKDLQ 1676
Query: 508 QHLE--------LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIV 559
L+ L++ + L + L L+ QEQ +R R E + I
Sbjct: 1677 MQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERIN 1736
Query: 560 DSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ + + ++ KLE +V +K+ EE+ + A+K + + + + +++ +
Sbjct: 1737 LFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQD 1796
Query: 619 TAARL 623
T A L
Sbjct: 1797 TIAHL 1801
Score = 50.4 bits (115), Expect = 2e-05
Identities = 59/300 (19%), Positives = 129/300 (43%), Gaps = 15/300 (5%)
Query: 343 KKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEID 399
K E+ + + + + ++ +L + LE++ L E+D++ ML +KE
Sbjct: 932 KSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKR 991
Query: 400 VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQ 459
+ + + L + + L A + + AH T ++ +++ S++ L L Q
Sbjct: 992 TTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQ 1051
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-K 518
+ D L+ + +ER E++L + + + + L++ + L + L ++ EL +
Sbjct: 1052 QVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQ 1111
Query: 519 CHYQKQLEDAVLAKLQ----EFQEQL-DRAER-EMENDARLKENNIVDSFNKQIL----R 568
+ + + E ++A+LQ E Q Q+ D E+ E E R K + + R
Sbjct: 1112 MNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNER 1171
Query: 569 IEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+EE + LE +++E K+ +L L E+ ++R ++ A L ++
Sbjct: 1172 LEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLH-FETTSASLKKRHADSLAELEGQVE 1230
Score = 37.1 bits (82), Expect = 0.20
Identities = 65/348 (18%), Positives = 140/348 (40%), Gaps = 30/348 (8%)
Query: 197 QELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIK 256
+EL+L +M EN + L K + + + + L E +AERTT K
Sbjct: 1105 KELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKL--EAERTTR---------AK 1153
Query: 257 LEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISK-LREAWLRLTNSLDR 315
+E ER A + K K + + + EA L +
Sbjct: 1154 MERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETTSAS 1213
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
+ RH +L ++ +VEN + V +K S + E+ D + +Q+ K +
Sbjct: 1214 LKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEV-------DDLLTRVEQMTRAKAN 1266
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDS 435
E+ + ++ + DK + + +L + + ++ LE EKE +
Sbjct: 1267 AEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLE---EKEALINQL 1323
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK 495
++ + ++I+ + + T+ + L + + + C ++ +Q E+Q +E+ +
Sbjct: 1324 SREK-SNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRT 1382
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA---VLAKLQEFQEQL 540
++ E+ ++ ++ + N ++ + LEDA + +LQE E +
Sbjct: 1383 LSKVNAEM--VQWRMKYENNVIQ--RTEDLEDAKKELAIRLQEAAEAM 1426
Score = 33.1 bits (72), Expect = 3.2
Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 4/74 (5%)
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
L E+ Q + L+K +F E+K + L +KN+L Q Q E LA ++E E L
Sbjct: 874 LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDL--ILQLQAEQETLANVEEQCEWLI 931
Query: 542 RAEREMENDARLKE 555
+++ ++E AR+KE
Sbjct: 932 KSKIQLE--ARVKE 943
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 54.8 bits (126), Expect = 9e-07
Identities = 73/351 (20%), Positives = 147/351 (41%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 808 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 867
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 868 LTEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 1100
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 1101 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 1149
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/302 (23%), Positives = 133/302 (44%), Gaps = 31/302 (10%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMI-CEVENFRVVADDAQKKTSHF 348
DRA+ A K +A L L +L+ A ++ + L K E+E+ DD K
Sbjct: 1465 DRAEAEAREKETKA-LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E + + + ++L++E ++ E+ +L E+ N+ M + ++++ E +
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV-NLQAMKAQFERDLQGRDEQSE- 1581
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
KQL V+ +E LE E+ +R +V L +DL
Sbjct: 1582 --EKKKQLVRQVREMEAELEDER-------------KQRSMAVAARKKLEMDLKDLEAHI 1626
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++R I+Q L + Q Q + +++ D D + ++NE K K +E
Sbjct: 1627 DSANKNRDEAIKQ-LRKLQAQMKDCMRELD--DTRASREEILAQAKENEKKL---KSME- 1679
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV--LEEKQR 585
A + +LQE +RA+R+ + + + I +S K L +EE+ +LE + LEE+
Sbjct: 1680 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1739
Query: 586 EE 587
EE
Sbjct: 1740 EE 1741
Score = 46.8 bits (106), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 1088
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVE----AQLQELQVKFNEG 1264
Query: 544 ER 545
ER
Sbjct: 1265 ER 1266
Score = 39.1 bits (87), Expect = 0.049
Identities = 71/293 (24%), Positives = 134/293 (45%), Gaps = 36/293 (12%)
Query: 343 KKTSHFESELYKTLDLAHD-------YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD 395
K S ES+L T +L + K KQ+++EK S EQL E + + N +
Sbjct: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH----NLE 1356
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
K+I L + V + K++ D V LE A E ++ + ++ L++R ++E +
Sbjct: 1357 KQIATL---HAQVADMKKKMEDSVGCLETAEEVKR----KLQKDLEGLSQR----HEEKV 1405
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS--EVLKKCDFLDNEVKTLRQHLELQ 513
+ + K+++ +E V ++Q+ C+ + KK D L E KT+ +
Sbjct: 1406 AAYDKLEKTKTRLQQELDDLLVDLDH--QRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 1463
Query: 514 KNELKCH-YQKQLEDAVLAK-LQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILR 568
++ + +K+ + LA+ L+E EQ ER + R + +++ D K +
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELER-LNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 569 IEEQHK-LEINVLEEK-QREEI--KLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E+ + LE V E K Q EE+ +L + A+ ++ L K + +R +G
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Score = 36.3 bits (80), Expect = 0.34
Identities = 61/314 (19%), Positives = 121/314 (38%), Gaps = 28/314 (8%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D K ++ I ++ + D ++ + + L A + + K K ++ E L+
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDT---VMRLNKQLTDCVKNLEEALEKEKFAHD 434
E+L +D+ D + + + ++L + LEE LE+E
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE----- 1741
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
+ N +N R++ N + D + + +N ERS E + + Q E+
Sbjct: 1742 --QGNTELINDRLKKAN-------LQIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME------ 548
K ++ VK+ + + E K ++ D + Q +Q+ R E++++
Sbjct: 1793 KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 549 NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ--LAQAAEKLGLLE 606
+D R D +K R+++ + EE QR +LQ L A E +
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 607 SKVEC--QRRRRGE 618
+V + RRG+
Sbjct: 1912 REVSSLKNKLRRGD 1925
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 54.8 bits (126), Expect = 9e-07
Identities = 58/303 (19%), Positives = 137/303 (45%), Gaps = 20/303 (6%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++++ D ++ ++E + L+ + K+ E+++ E R + + + + FE
Sbjct: 1162 QIEKLSDKVVASVKEG---VQGPLNVSLSEEGKSQEQIL---EILRFIRREKEIAETRFE 1215
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK--ENYDT 407
++L Y+ + + L+ E + LE+ LN E + V V + +++K E +
Sbjct: 1216 VAQVESLR----YRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNV 1271
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
VM NK L + + LE+ L++ + + +I L + +++++ +L E+ LL+
Sbjct: 1272 VMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Query: 468 VNEERSRCA-VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
V ++R ++ QQ + ++L + + ++ L + + K E+
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-----QILRIEEQHKLEINVLE 581
+ L +Q +E L++ E E + + I+D K Q+ +I ++K + L+
Sbjct: 1392 NQNL--IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK 1449
Query: 582 EKQ 584
+Q
Sbjct: 1450 AQQ 1452
Score = 49.2 bits (112), Expect = 5e-05
Identities = 67/331 (20%), Positives = 150/331 (45%), Gaps = 30/331 (9%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV----VADDAQKKTSHFESELYKT 355
++L + + + +D R+A+E M ++ + V ++ Q+ + L
Sbjct: 1002 TQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLN 412
D Q++ K + E +L +V + + K+ K V + +T +
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAE 1121
Query: 413 KQLTDCVKNLEEA--LEKEKFA------HDSTKSNITELNKRIQSVNDETLLLTQE--RD 462
QL +C + EE + K++ + D K N L+ +I+ ++D+ + +E +
Sbjct: 1122 SQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRL-LHDQIEKLSDKVVASVKEGVQG 1180
Query: 463 LLKSKVNEE-RSRCAVIE-QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
L ++EE +S+ ++E + ++ + +E + + E RQ +EL + EL+
Sbjct: 1181 PLNVSLSEEGKSQEQILEILRFIRREKEIAET--RFEVAQVESLRYRQRVELLERELQ-- 1236
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL 580
+LED++ A+ ++ Q + E + + N+V NK + +E+ + ++ +
Sbjct: 1237 ---ELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQM 1293
Query: 581 EEKQRE-EIKLYRLQLAQA--AEKLGLLESK 608
+ K R+ E+ + LQ A A +EK G+L+++
Sbjct: 1294 QAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Score = 45.2 bits (102), Expect = 7e-04
Identities = 70/377 (18%), Positives = 154/377 (40%), Gaps = 40/377 (10%)
Query: 218 QNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXX 277
Q + I+T+ DL +E R + + +++KL E RL ++ E+++
Sbjct: 756 QEQIINTMTQDLRGANEKLAVAEVRAENLKK--EKEMLKLSEVRLSQQR-ESLLAEQRGQ 812
Query: 278 XXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ ++R++ +L +L + + + + +E+ N V
Sbjct: 813 NLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQ 872
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE-------------- 383
D +++ + T +L + Q + L+ ++E Q+ ++
Sbjct: 873 LLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Query: 384 -LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-- 440
+D++ L +++++ LKE T +Q V +LEE+L KEK + + NI
Sbjct: 933 DVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Query: 441 ---------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
T+L K++ V E L ++ + + + + +++ L QN+ E
Sbjct: 993 RLKESAEFQTQLEKKLMEVEKEKQELQDDK---RRAIESMEQQLSELKKTLSSVQNEVQE 1049
Query: 492 VLKKCD-FLDNEVKTLRQHLELQK--NELKCHYQKQ--LEDAVLAKLQEFQEQLDR---A 543
L++ L NE + R E K E + Y+++ L A + LQ +EQ+ +
Sbjct: 1050 ALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV 1109
Query: 544 EREMENDARLKENNIVD 560
+ +E + E+ +++
Sbjct: 1110 RQHLEETTQKAESQLLE 1126
Score = 41.1 bits (92), Expect = 0.012
Identities = 61/306 (19%), Positives = 124/306 (40%), Gaps = 19/306 (6%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT-ELDNVN 388
E E Q K E ++ + + +K LQ EKK LEE + + N +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 389 VMLSNKDKEID----VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
++ KD + + +L E R+ +QLT+ + L+ + + + + ++ I L
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTKRI-QQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD-FLDNEV 503
+ + V E + ++ D + E+ +++ + Q E+ + D ++
Sbjct: 1401 EDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSA 1460
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER---EMENDAR-LKENNIV 559
++ H E + + K+ + K + + Q++ ++ E E +AR L+E +
Sbjct: 1461 QSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 560 DSFNKQILRI--------EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
LR EEQ + +I EEK R+ I + ++A A L + E
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEE 1580
Query: 612 QRRRRG 617
++R G
Sbjct: 1581 LKQRNG 1586
Score = 39.9 bits (89), Expect = 0.028
Identities = 66/297 (22%), Positives = 130/297 (43%), Gaps = 37/297 (12%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
C +EN + +++ + ++ D K K+ + ++ S+EE+ + EL N +
Sbjct: 224 CNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 389 VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ LSN + K D + +LT V+ L + L++ A+ + + ++ E+ +
Sbjct: 283 IKLSN------LYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336
Query: 449 SVNDETL----LLTQERDLLKSKVNEERSRCAVI-EQQLCEKQNQCSEVLK------KCD 497
+ E L L +E + ++ + + A++ E++L + V K K
Sbjct: 337 QMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLT 396
Query: 498 FLDNEVKTLRQHLELQKNELK--CHYQKQLEDAVLAK---LQEFQEQLDRA--------- 543
L N + L L+K E K Y ++ V AK L+ +E+ +RA
Sbjct: 397 ELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSV 456
Query: 544 --EREMENDARLKENNIVDSFNKQILRIE-EQHKLEINVLEEKQREEIKLYRLQLAQ 597
E+ M+ RL+E+ D NKQ +E + ++EI V + Q+ + L L+ A+
Sbjct: 457 KLEQAMKEIQRLQED--TDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 511
Score = 39.5 bits (88), Expect = 0.037
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNI---TELNKRIQSVN 451
+E+ LKE + +K L V+NL++ L EKE A + + + +EL++ Q +
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
D T Q R + K EE++R A++ + K + V + + E+K L+
Sbjct: 1534 DRTTQEEQLRQQITEK--EEKTRKAIVAAK--SKIAHLAGVKDQLTKENEELKQRNGALD 1589
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQL-DRAEREME-NDARLKENNIVDSFNKQI 566
QK+EL L+ ++ + +L + ER +E D + +N V +QI
Sbjct: 1590 QQKDELDVRI-TALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQI 1645
Score = 35.1 bits (77), Expect = 0.80
Identities = 54/277 (19%), Positives = 120/277 (43%), Gaps = 26/277 (9%)
Query: 367 KQLQNEKKSLEEQLNTELDNVN-----VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
K +QN+ + +E+D + + ++ + ++ K + RL + +C ++
Sbjct: 19 KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETREC-QS 77
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
L LEK ++ K+ +TE NK ++ D + + + K ++ E+ ++
Sbjct: 78 LRLELEK---LNNQLKA-LTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER 133
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH--YQKQLEDAVLAKLQEFQEQ 539
L ++ +E +K+ + E T + L+L+ +EL+ K E +L++ +E
Sbjct: 134 LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE----KRLEQEKEL 189
Query: 540 LDRAEREMENDARLKENNIV---DSFNKQILRIE---EQHKLEINVLEEKQREEIKLYRL 593
L + + + K + ++ +IL ++ E K E++ LEE Q +K
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE-QMNGLKTSNE 248
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L + E L +K++ + ++ + H L AH
Sbjct: 249 HLQKHVED---LLTKLKEAKEQQASMEEKFHNELNAH 282
>X58677-1|CAA41528.1| 608|Homo sapiens hemidesmosomal plaque
protein protein.
Length = 608
Score = 54.8 bits (126), Expect = 9e-07
Identities = 51/275 (18%), Positives = 119/275 (43%), Gaps = 16/275 (5%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL 384
E ++ E + + + + + F+ +L T + H + Q + K LEE L
Sbjct: 4 ENIVLEKQTIQQRCEALKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQ 63
Query: 385 DNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
+ V+ D++ +++ V LN +L + +K + ++ + ELN
Sbjct: 64 NLVSEFKQKCDQQNIIIQNTKKEVRNLNAELNASKEEKRRGEQKVQLQ----QAQVQELN 119
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
R++ V DE L T E + K+ + +Q E + + ++++ +N++
Sbjct: 120 NRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDIS 179
Query: 505 TLR-QHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+R + LQ+ + +L + ++E + QL + +M+ ++ N+
Sbjct: 180 GIRLDFVSLQQENSRAQENAKLCE---TNIKELERQLQQYREQMQQGQHMEANHY----- 231
Query: 564 KQILRIEEQ---HKLEINVLEEKQREEIKLYRLQL 595
++ ++E++ K E+ L++K ++IK + QL
Sbjct: 232 QKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQL 266
Score = 48.0 bits (109), Expect = 1e-04
Identities = 52/232 (22%), Positives = 96/232 (41%), Gaps = 14/232 (6%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQ----LQNEKKSLEEQLNTELDNVNVMLSNKD 395
D Q+K E +L K+ +L +++ KC Q +QN KK + LN EL N K
Sbjct: 47 DFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKKEVRN-LNAEL---NASKEEKR 102
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+ ++ V LN +L L +E+ H E K QS +
Sbjct: 103 RGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQMTHRKMVLFQEESGKFKQSAEE--- 159
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
+ L++SKV E + I Q + S + + +K L + L+ +
Sbjct: 160 FRKKMEKLMESKVITEND-ISGIRLDFVSLQQENSRAQENAKLCETNIKELERQLQQYRE 218
Query: 516 ELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQIL 567
+++ + +E K Q+ +++L +RE+EN + + I + ++ +L
Sbjct: 219 QMQ--QGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQIKEHEHQLVL 268
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 54.8 bits (126), Expect = 9e-07
Identities = 73/351 (20%), Positives = 147/351 (41%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 808 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 867
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 868 LTEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 1100
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 1101 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 1149
Score = 46.8 bits (106), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 1088
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVE----AQLQELQVKFNEG 1264
Query: 544 ER 545
ER
Sbjct: 1265 ER 1266
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 54.8 bits (126), Expect = 9e-07
Identities = 73/351 (20%), Positives = 147/351 (41%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 808 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 867
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 868 LTEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 1100
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 1101 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 1149
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/302 (23%), Positives = 133/302 (44%), Gaps = 31/302 (10%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMI-CEVENFRVVADDAQKKTSHF 348
DRA+ A K +A L L +L+ A ++ + L K E+E+ DD K
Sbjct: 1465 DRAEAEAREKETKA-LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E + + + ++L++E ++ E+ +L E+ N+ M + ++++ E +
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV-NLQAMKAQFERDLQGRDEQSE- 1581
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
KQL V+ +E LE E+ +R +V L +DL
Sbjct: 1582 --EKKKQLVRQVREMEAELEDER-------------KQRSMAVAARKKLEMDLKDLEAHI 1626
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++R I+Q L + Q Q + +++ D D + ++NE K K +E
Sbjct: 1627 DSANKNRDEAIKQ-LRKLQAQMKDCMRELD--DTRASREEILAQAKENEKKL---KSME- 1679
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV--LEEKQR 585
A + +LQE +RA+R+ + + + I +S K L +EE+ +LE + LEE+
Sbjct: 1680 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1739
Query: 586 EE 587
EE
Sbjct: 1740 EE 1741
Score = 46.8 bits (106), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 1088
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVE----AQLQELQVKFNEG 1264
Query: 544 ER 545
ER
Sbjct: 1265 ER 1266
Score = 39.1 bits (87), Expect = 0.049
Identities = 71/293 (24%), Positives = 134/293 (45%), Gaps = 36/293 (12%)
Query: 343 KKTSHFESELYKTLDLAHD-------YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD 395
K S ES+L T +L + K KQ+++EK S EQL E + + N +
Sbjct: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH----NLE 1356
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
K+I L + V + K++ D V LE A E ++ + ++ L++R ++E +
Sbjct: 1357 KQIATL---HAQVADMKKKMEDSVGCLETAEEVKR----KLQKDLEGLSQR----HEEKV 1405
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS--EVLKKCDFLDNEVKTLRQHLELQ 513
+ + K+++ +E V ++Q+ C+ + KK D L E KT+ +
Sbjct: 1406 AAYDKLEKTKTRLQQELDDLLVDLDH--QRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 1463
Query: 514 KNELKCH-YQKQLEDAVLAK-LQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILR 568
++ + +K+ + LA+ L+E EQ ER + R + +++ D K +
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELER-LNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 569 IEEQHK-LEINVLEEK-QREEI--KLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E+ + LE V E K Q EE+ +L + A+ ++ L K + +R +G
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Score = 36.3 bits (80), Expect = 0.34
Identities = 61/314 (19%), Positives = 121/314 (38%), Gaps = 28/314 (8%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D K ++ I ++ + D ++ + + L A + + K K ++ E L+
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDT---VMRLNKQLTDCVKNLEEALEKEKFAHD 434
E+L +D+ D + + + ++L + LEE LE+E
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE----- 1741
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
+ N +N R++ N + D + + +N ERS E + + Q E+
Sbjct: 1742 --QGNTELINDRLKKAN-------LQIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME------ 548
K ++ VK+ + + E K ++ D + Q +Q+ R E++++
Sbjct: 1793 KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 549 NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ--LAQAAEKLGLLE 606
+D R D +K R+++ + EE QR +LQ L A E +
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 607 SKVEC--QRRRRGE 618
+V + RRG+
Sbjct: 1912 REVSSLKNKLRRGD 1925
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 54.8 bits (126), Expect = 9e-07
Identities = 73/351 (20%), Positives = 147/351 (41%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 808 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 867
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 868 LTEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 1100
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 1101 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 1149
Score = 46.8 bits (106), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 1088
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVE----AQLQELQVKFNEG 1264
Query: 544 ER 545
ER
Sbjct: 1265 ER 1266
>AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-1
protein.
Length = 685
Score = 54.8 bits (126), Expect = 9e-07
Identities = 78/331 (23%), Positives = 144/331 (43%), Gaps = 25/331 (7%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
+A I+KL E L + +E +K E CE+EN R +A + L +
Sbjct: 12 EAEINKLNELKENLVKQCEASEKNIQKKYE---CELENLRKATSNANQDNQICSILLQEN 68
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQ 414
+ +K K L++ K LE Q + D V M + K K E+D + D +
Sbjct: 69 TFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDA-QHIKDEFFHERED 127
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKR----IQSVNDETLLLTQERDLLKSKVNE 470
L + L A E++ + KS + LNK+ ++ N E L ++ S++NE
Sbjct: 128 LEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNE 187
Query: 471 ------ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-----KC 519
E+ + ++ ++ + QC + ++ ++LR+ +E+ + EL K
Sbjct: 188 TFLSDSEKEKLTLM-FEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKI 246
Query: 520 HYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
+ + ++ + + E Q++L A E DA L+ N + N+++L +E N
Sbjct: 247 SQEFESMKQQQASDVHELQQKLRTA--FTEKDALLETVNRLQGENEKLLSQQELVPELEN 304
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
++ Q E+ +Y L L+Q L LE K+
Sbjct: 305 TIKNLQ-EKNGVYLLSLSQRDTMLKELEGKI 334
Score = 44.0 bits (99), Expect = 0.002
Identities = 42/183 (22%), Positives = 82/183 (44%), Gaps = 6/183 (3%)
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
KE+ + +LN+ + VK E + + + ++ N+ + N +L QE
Sbjct: 9 KEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQEN 68
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
++ VNE+ +E L E ++Q S + + +++N L + K+E H
Sbjct: 69 TFVEQVVNEKVKH---LEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEF-FHE 124
Query: 522 QKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN--NIVDSFNKQILRIEEQHKLEINV 579
++ LE + L +EQ E+ A L + V+ N+++ ++EQH+ EI+
Sbjct: 125 REDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISE 184
Query: 580 LEE 582
L E
Sbjct: 185 LNE 187
Score = 40.7 bits (91), Expect = 0.016
Identities = 65/298 (21%), Positives = 134/298 (44%), Gaps = 30/298 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
KD I+KL+ + + N + E R LE + +VE + ++K + L +
Sbjct: 341 KDDFINKLKNSHEEMDNFHKKCEREERLILE-LGKKVEQTIQYNSELEQKVNELTGGLEE 399
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQ---LNTEL-----DNVNVMLSNKD--KEIDV-LKE 403
TL K ++L + K L E L+ E+ + +N + K ++++V L +
Sbjct: 400 TLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEETINSVQKKKQLSRDLEVFLSQ 459
Query: 404 NYDTVMR-----LNKQLTDCVK---NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
D +++ L K+L V+ NL + LE E+ K T+L ++ + E
Sbjct: 460 KEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVK---TQLYGFLKEMGSEVS 516
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++E+D++ + + A I ++ C Q E + + L+ E+K L++ +Q
Sbjct: 517 EDSEEKDVV-NVLQAVGESLAKINEEKCNLAFQRDEKVLE---LEKEIKCLQEESVVQCE 572
Query: 516 ELKCHYQKQLEDAVLAK--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
ELK + ++ VL + L+E Q + + + ++ E +++ N ++++EE
Sbjct: 573 ELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQN-LLIQVEE 629
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 54.8 bits (126), Expect = 9e-07
Identities = 78/331 (23%), Positives = 144/331 (43%), Gaps = 25/331 (7%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
+A I+KL E L + +E +K E CE+EN R +A + L +
Sbjct: 166 EAEINKLNELKENLVKQCEASEKNIQKKYE---CELENLRKATSNANQDNQICSILLQEN 222
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQ 414
+ +K K L++ K LE Q + D V M + K K E+D + D +
Sbjct: 223 TFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDA-QHIKDEFFHERED 281
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKR----IQSVNDETLLLTQERDLLKSKVNE 470
L + L A E++ + KS + LNK+ ++ N E L ++ S++NE
Sbjct: 282 LEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNE 341
Query: 471 ------ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-----KC 519
E+ + ++ ++ + QC + ++ ++LR+ +E+ + EL K
Sbjct: 342 TFLSDSEKEKLTLM-FEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKI 400
Query: 520 HYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
+ + ++ + + E Q++L A E DA L+ N + N+++L +E N
Sbjct: 401 SQEFESMKQQQASDVHELQQKLRTA--FTEKDALLETVNRLQGENEKLLSQQELVPELEN 458
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
++ Q E+ +Y L L+Q L LE K+
Sbjct: 459 TIKNLQ-EKNGVYLLSLSQRDTMLKELEGKI 488
Score = 46.8 bits (106), Expect = 2e-04
Identities = 71/307 (23%), Positives = 130/307 (42%), Gaps = 25/307 (8%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMICE---VENFRVVADDAQKKTSHFESE-- 351
A SK E L L+ A + + E++ + +N + + ++ +K FE +
Sbjct: 39 AVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQIL 98
Query: 352 -LYKTLDLAHDYQ-DKCKQLQN--EKKSLEEQLNT-----ELDNVNVMLSNKDKEIDV-- 400
L K LD D + + QLQN E S Q N EL + + + KE+
Sbjct: 99 YLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQI 158
Query: 401 ---LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
KE+ + +LN+ + VK E + + + ++ N+ + N +L
Sbjct: 159 EASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSIL 218
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
QE ++ VNE+ +E L E ++Q S + + +++N L + K+E
Sbjct: 219 LQENTFVEQVVNEKVKH---LEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEF 275
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN--NIVDSFNKQILRIEEQHKL 575
H ++ LE + L +EQ E+ A L + V+ N+++ ++EQH+
Sbjct: 276 -FHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQK 334
Query: 576 EINVLEE 582
EI+ L E
Sbjct: 335 EISELNE 341
Score = 44.4 bits (100), Expect = 0.001
Identities = 58/266 (21%), Positives = 122/266 (45%), Gaps = 22/266 (8%)
Query: 360 HDYQDKC--KQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
H+ ++KC K+ +N K LE+ +L + ++ + K V + +V K+L
Sbjct: 794 HNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSV----KELE 849
Query: 417 DCVKNLE-EALEKE------KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
+ ++NLE E EKE K K + K Q+V +E L E+D L + +
Sbjct: 850 EKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMR 909
Query: 470 EERSRCAVIEQQLC--EKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ + L EKQ++ +V K + + ++ ++ L + +L+ + L+C
Sbjct: 910 DLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTR--QLRNSTLQCETINSDN 967
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
+ +LA+++ Q E ++ R K + +++ Q + ++H +N LEE Q
Sbjct: 968 EDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQ 1027
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVE 610
+++ + QL + ++L L++ +
Sbjct: 1028 -VQLQKQKKQLQKTMQELELVKKDAQ 1052
Score = 42.3 bits (95), Expect = 0.005
Identities = 66/298 (22%), Positives = 134/298 (44%), Gaps = 30/298 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
KD I+KL+ + + N + E R LE + +VE + ++K + L +
Sbjct: 495 KDDFINKLKNSHEEMDNFHKKCEREERLILE-LGKKVEQTIQYNSELEQKVNELTGGLEE 553
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNV---NVMLSNKDKEID-----VLKE 403
TL K ++L + K L E L+ E+ ++ N LS++ K++ L +
Sbjct: 554 TLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQ 613
Query: 404 NYDTVMR-----LNKQLTDCVK---NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
D +++ L K+L V+ NL + LE E+ K T+L ++ + E
Sbjct: 614 KEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVK---TQLYGFLKEMGSEVS 670
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++E+D++ + + A I ++ C Q E + + L+ E+K L++ +Q
Sbjct: 671 EDSEEKDVV-NVLQAVGESLAKINEEKCNLAFQRDEKVLE---LEKEIKCLQEESVVQCE 726
Query: 516 ELKCHYQKQLEDAVLAK--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
ELK + ++ VL + L+E Q + + + ++ E +++ N ++++EE
Sbjct: 727 ELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQN-LLIQVEE 783
Score = 39.9 bits (89), Expect = 0.028
Identities = 59/302 (19%), Positives = 127/302 (42%), Gaps = 34/302 (11%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF------ESELYKT 355
L+E L +S+ + E+++ K + + V+ + +AD Q +T H + EL +
Sbjct: 1099 LQEEITSLQSSVQQYEEKNTKIKQLL---VKTKKELADSKQAETDHLILQASLKGELEAS 1155
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
Y+ + ++ +EK + E L T + LS + + L+E
Sbjct: 1156 QQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEE----------- 1204
Query: 416 TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
K + + E ++ N+ + K ET QER+ L+ +++
Sbjct: 1205 CRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQ----- 1259
Query: 476 AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQ 534
++ +L + QN + + L +E TL LE L+ K+ E L +Q
Sbjct: 1260 --LKIKLQDSQNNLQINVSELQTLQSEHDTL---LERHNKMLQETVSKEAELREKLCSIQ 1314
Query: 535 EFQEQLDRAEREMENDARLKENNIV-DSFNKQILRIEEQHKLEINVLEEK-QREEIKLYR 592
+ + ++E +N ++ +SF Q+ ++E+H+ + L+++ + E +L++
Sbjct: 1315 S-ENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQ 1373
Query: 593 LQ 594
L+
Sbjct: 1374 LK 1375
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 54.8 bits (126), Expect = 9e-07
Identities = 73/351 (20%), Positives = 147/351 (41%), Gaps = 19/351 (5%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLD-----RAEDRHRKALEKMICEVENFRVVADDA 341
AMKV + AA KLR W RL + ++ A E+ + +V ++ A++
Sbjct: 808 AMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENR 867
Query: 342 QKKTSHFESELY-KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
+ +S+L + L L Q + +L E + L +L + + + + + ++
Sbjct: 868 LTEMETLQSQLMAEKLQLQEQLQAET-ELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E + K++ ++ LEE LE+E+ A + +++ + +E ++L +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQ 986
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNEL 517
L + R A L E++ + + K + + + L + L E Q+ EL
Sbjct: 987 NCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL 1046
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+ +K D+ Q + Q AE +M+ KE + + R+EE+ +
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQ--LAKKE----EELQAALARVEEEAAQKN 1100
Query: 578 NVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L++ + E ++ LQ +E+ +K E Q+R GE L L+
Sbjct: 1101 MALKKIRELESQISELQEDLESERAS--RNKAEKQKRDLGEELEALKTELE 1149
Score = 48.0 bits (109), Expect = 1e-04
Identities = 72/302 (23%), Positives = 133/302 (44%), Gaps = 31/302 (10%)
Query: 292 DRAKDAAISKLREAWLRLTNSLDRAEDRHRKA--LEKMI-CEVENFRVVADDAQKKTSHF 348
DRA+ A K +A L L +L+ A ++ + L K E+E+ DD K
Sbjct: 1465 DRAEAEAREKETKA-LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E + + + ++L++E ++ E+ +L E+ N+ M + ++++ E +
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV-NLQAMKAQFERDLQGRDEQSE- 1581
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
KQL V+ +E LE E+ +R +V L +DL
Sbjct: 1582 --EKKKQLVRQVREMEAELEDER-------------KQRSMAVAARKKLEMDLKDLEAHI 1626
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
+ ++R I+Q L + Q Q + +++ D D + ++NE K K +E
Sbjct: 1627 DSANKNRDEAIKQ-LRKLQAQMKDCMRELD--DTRASREEILAQAKENEKKL---KSME- 1679
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV--LEEKQR 585
A + +LQE +RA+R+ + + + I +S K L +EE+ +LE + LEE+
Sbjct: 1680 AEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELE 1739
Query: 586 EE 587
EE
Sbjct: 1740 EE 1741
Score = 46.8 bits (106), Expect = 2e-04
Identities = 68/302 (22%), Positives = 127/302 (42%), Gaps = 22/302 (7%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD- 314
KLEEE++ E + + + K +++KL+ + L+
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 315 --RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE 372
R E++ R+ LEK ++E + D + + ++++ +L K ++LQ
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGD---STDLSDQIAELQAQI---AELKMQLAKKEEELQAA 1088
Query: 373 KKSLEE---QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
+EE Q N L + + S + + L+ + + KQ D + LE +
Sbjct: 1089 LARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTEL 1148
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ DST + +KR Q VN L +E ++++ E R + + ++L E+ Q
Sbjct: 1149 EDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQT 1208
Query: 490 SEV---LKKC-DFLDNEVKTLRQHLE--LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
V L+K L+NE L ++ LQ H +K++E A+LQE Q + +
Sbjct: 1209 KRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVE----AQLQELQVKFNEG 1264
Query: 544 ER 545
ER
Sbjct: 1265 ER 1266
Score = 39.1 bits (87), Expect = 0.049
Identities = 71/293 (24%), Positives = 134/293 (45%), Gaps = 36/293 (12%)
Query: 343 KKTSHFESELYKTLDLAHD-------YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD 395
K S ES+L T +L + K KQ+++EK S EQL E + + N +
Sbjct: 1301 KDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH----NLE 1356
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
K+I L + V + K++ D V LE A E ++ + ++ L++R ++E +
Sbjct: 1357 KQIATL---HAQVADMKKKMEDSVGCLETAEEVKR----KLQKDLEGLSQR----HEEKV 1405
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS--EVLKKCDFLDNEVKTLRQHLELQ 513
+ + K+++ +E V ++Q+ C+ + KK D L E KT+ +
Sbjct: 1406 AAYDKLEKTKTRLQQELDDLLVDLDH--QRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 1463
Query: 514 KNELKCH-YQKQLEDAVLAK-LQEFQEQLDRAEREMENDARLKENNIV---DSFNKQILR 568
++ + +K+ + LA+ L+E EQ ER + R + +++ D K +
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELER-LNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 569 IEEQHK-LEINVLEEK-QREEI--KLYRLQLAQAAEKLGLLESKVECQRRRRG 617
+E+ + LE V E K Q EE+ +L + A+ ++ L K + +R +G
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 1575
Score = 36.3 bits (80), Expect = 0.34
Identities = 61/314 (19%), Positives = 121/314 (38%), Gaps = 28/314 (8%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D K ++ I ++ + D ++ + + L A + + K K ++ E L+
Sbjct: 1627 DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQ 1686
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDT---VMRLNKQLTDCVKNLEEALEKEKFAHD 434
E+L +D+ D + + + ++L + LEE LE+E
Sbjct: 1687 EELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEE----- 1741
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
+ N +N R++ N + D + + +N ERS E + + Q E+
Sbjct: 1742 --QGNTELINDRLKKAN-------LQIDQINTDLNLERSHAQKNENARQQLERQNKELKV 1792
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME------ 548
K ++ VK+ + + E K ++ D + Q +Q+ R E++++
Sbjct: 1793 KLQEMEGTVKS-KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQV 1851
Query: 549 NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ--LAQAAEKLGLLE 606
+D R D +K R+++ + EE QR +LQ L A E +
Sbjct: 1852 DDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMN 1911
Query: 607 SKVEC--QRRRRGE 618
+V + RRG+
Sbjct: 1912 REVSSLKNKLRRGD 1925
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 54.8 bits (126), Expect = 9e-07
Identities = 78/331 (23%), Positives = 144/331 (43%), Gaps = 25/331 (7%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
+A I+KL E L + +E +K E CE+EN R +A + L +
Sbjct: 218 EAEINKLNELKENLVKQCEASEKNIQKKYE---CELENLRKATSNANQDNQICSILLQEN 274
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLNKQ 414
+ +K K L++ K LE Q + D V M + K K E+D + D +
Sbjct: 275 TFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDA-QHIKDEFFHERED 333
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKR----IQSVNDETLLLTQERDLLKSKVNE 470
L + L A E++ + KS + LNK+ ++ N E L ++ S++NE
Sbjct: 334 LEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNE 393
Query: 471 ------ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-----KC 519
E+ + ++ ++ + QC + ++ ++LR+ +E+ + EL K
Sbjct: 394 TFLSDSEKEKLTLM-FEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKI 452
Query: 520 HYQ-KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
+ + ++ + + E Q++L A E DA L+ N + N+++L +E N
Sbjct: 453 SQEFESMKQQQASDVHELQQKLRTA--FTEKDALLETVNRLQGENEKLLSQQELVPELEN 510
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKV 609
++ Q E+ +Y L L+Q L LE K+
Sbjct: 511 TIKNLQ-EKNGVYLLSLSQRDTMLKELEGKI 540
Score = 46.8 bits (106), Expect = 2e-04
Identities = 71/307 (23%), Positives = 130/307 (42%), Gaps = 25/307 (8%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMICE---VENFRVVADDAQKKTSHFESE-- 351
A SK E L L+ A + + E++ + +N + + ++ +K FE +
Sbjct: 91 AVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQIL 150
Query: 352 -LYKTLDLAHDYQ-DKCKQLQN--EKKSLEEQLNT-----ELDNVNVMLSNKDKEIDV-- 400
L K LD D + + QLQN E S Q N EL + + + KE+
Sbjct: 151 YLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQI 210
Query: 401 ---LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL 457
KE+ + +LN+ + VK E + + + ++ N+ + N +L
Sbjct: 211 EASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSIL 270
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL 517
QE ++ VNE+ +E L E ++Q S + + +++N L + K+E
Sbjct: 271 LQENTFVEQVVNEKVKH---LEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEF 327
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKEN--NIVDSFNKQILRIEEQHKL 575
H ++ LE + L +EQ E+ A L + V+ N+++ ++EQH+
Sbjct: 328 -FHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQK 386
Query: 576 EINVLEE 582
EI+ L E
Sbjct: 387 EISELNE 393
Score = 44.0 bits (99), Expect = 0.002
Identities = 58/266 (21%), Positives = 122/266 (45%), Gaps = 22/266 (8%)
Query: 360 HDYQDKC--KQLQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
H+ ++KC K+ +N K LE+ +L + ++ + K V + +V K+L
Sbjct: 846 HNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSV----KELE 901
Query: 417 DCVKNLE-EALEKE------KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
+ ++NLE E EKE K K + K Q+V +E L E+D L + +
Sbjct: 902 EKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMR 961
Query: 470 EERSRCAVIEQQLC--EKQNQCSEVLK-KCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ + L EKQ++ +V K + + ++ ++ L + +L+ + L+C
Sbjct: 962 DLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTR--QLRNSTLQCETINSDN 1019
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
+ +LA+++ Q E ++ R K + +++ Q + ++H +N LEE Q
Sbjct: 1020 EDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQ 1079
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVE 610
+++ + QL + ++L L++ +
Sbjct: 1080 -VQLQKEKKQLQKTMQELELVKKDAQ 1104
Score = 42.3 bits (95), Expect = 0.005
Identities = 66/298 (22%), Positives = 134/298 (44%), Gaps = 30/298 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
KD I+KL+ + + N + E R LE + +VE + ++K + L +
Sbjct: 547 KDDFINKLKNSHEEMDNFHKKCEREERLILE-LGKKVEQTIQYNSELEQKVNELTGGLEE 605
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQ---LNTELDNV---NVMLSNKDKEID-----VLKE 403
TL K ++L + K L E L+ E+ ++ N LS++ K++ L +
Sbjct: 606 TLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQ 665
Query: 404 NYDTVMR-----LNKQLTDCVK---NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
D +++ L K+L V+ NL + LE E+ K T+L ++ + E
Sbjct: 666 KEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVK---TQLYGFLKEMGSEVS 722
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
++E+D++ + + A I ++ C Q E + + L+ E+K L++ +Q
Sbjct: 723 EDSEEKDVV-NVLQAVGESLAKINEEKCNLAFQRDEKVLE---LEKEIKCLQEESVVQCE 778
Query: 516 ELKCHYQKQLEDAVLAK--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
ELK + ++ VL + L+E Q + + + ++ E +++ N ++++EE
Sbjct: 779 ELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQN-LLIQVEE 835
Score = 39.9 bits (89), Expect = 0.028
Identities = 59/302 (19%), Positives = 127/302 (42%), Gaps = 34/302 (11%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF------ESELYKT 355
L+E L +S+ + E+++ K + + V+ + +AD Q +T H + EL +
Sbjct: 1151 LQEEITSLQSSVQQYEEKNTKIKQLL---VKTKKELADSKQAETDHLILQASLKGELEAS 1207
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
Y+ + ++ +EK + E L T + LS + + L+E
Sbjct: 1208 QQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEE----------- 1256
Query: 416 TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
K + + E ++ N+ + K ET QER+ L+ +++
Sbjct: 1257 CRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQ----- 1311
Query: 476 AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQ 534
++ +L + QN + + L +E TL LE L+ K+ E L +Q
Sbjct: 1312 --LKIKLQDSQNNLQINVSELQTLQSEHDTL---LERHNKMLQETVSKEAELREKLCSIQ 1366
Query: 535 EFQEQLDRAEREMENDARLKENNIV-DSFNKQILRIEEQHKLEINVLEEK-QREEIKLYR 592
+ + ++E +N ++ +SF Q+ ++E+H+ + L+++ + E +L++
Sbjct: 1367 S-ENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQ 1425
Query: 593 LQ 594
L+
Sbjct: 1426 LK 1427
Score = 34.7 bits (76), Expect = 1.1
Identities = 56/277 (20%), Positives = 127/277 (45%), Gaps = 40/277 (14%)
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
D + + LQ+ K LE Q+ E+ M+ DKE++ K + ++ + + ++
Sbjct: 1021 DLLARIETLQSNAKLLEVQI-LEVQRAKAMV---DKELEAEKLQKEQKIKEHATTVNELE 1076
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
L+ L+KEK K++Q QE +L+K ++ + ++
Sbjct: 1077 ELQVQLQKEK--------------KQLQKT-------MQELELVK----KDAQQTTLMNM 1111
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
++ + + E+ +K +N+++ L Q +++QK + Q+ L++ + LQ +Q
Sbjct: 1112 EIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQK-----QETLQEEI-TSLQSSVQQY 1165
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ-AA 599
+ +++ + + DS + + Q L+ + E ++++++Y++QLA+ +
Sbjct: 1166 EEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL--EASQQQVEVYKIQLAEITS 1223
Query: 600 EKLGLLES-KVECQRRRRGETAARLH-AALQAHWRHA 634
EK + E K ++ +R +A + ALQ R A
Sbjct: 1224 EKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAA 1260
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 54.4 bits (125), Expect = 1e-06
Identities = 69/324 (21%), Positives = 156/324 (48%), Gaps = 18/324 (5%)
Query: 307 LRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDY---Q 363
L L L++ + R+ E+ ++E R A ++ E E + +L + Q
Sbjct: 431 LELEKRLEKQRELERQREEERRKDIER-REAAKQELERQRRLEWERIRRQELLNQKNREQ 489
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC----V 419
++ +L ++KK+L +L L+ + +S + +++ + K+ T + + + D +
Sbjct: 490 EEIVRLNSKKKNLHLELEA-LNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEI 548
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
K L++ L++ + LN+RI+++ LL K E+ C ++
Sbjct: 549 KQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTP-DSGVSLLHKKSLEKEELCQRLK 607
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
+QL + + + L + D +N++K LR+ Q+ L+ Y +++ L +++ + +
Sbjct: 608 EQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLY--KIKRDKLKEIERKRLE 665
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
L ++++E++A K ++ K+ LR EE+ K + + EEK +E+I + + +A
Sbjct: 666 L-MQKKKLEDEAARKAKQGKENLWKENLRKEEEEK-QKRLQEEKTQEKI---QEEERKAE 720
Query: 600 EKLGLLESKVECQRRRRGETAARL 623
EK + ++ + ++R ETA+ L
Sbjct: 721 EKQRKDKDTLKAEEKKR-ETASVL 743
Score = 31.9 bits (69), Expect = 7.4
Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 514 KNELKCHYQK---QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
+++ K +Y++ +LE A +++ Q + +R ++ + + K+ + + K+ L +E
Sbjct: 375 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 434
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +LE E+QREE + ++ +AA++ + ++E +R RR E
Sbjct: 435 K--RLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 480
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 54.4 bits (125), Expect = 1e-06
Identities = 74/339 (21%), Positives = 156/339 (46%), Gaps = 29/339 (8%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQ 370
+ L++ ++R ++ L+ ++ +++N R + + +KK F+ L + +++ Y D+ + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 371 NE-----------KKSLEEQLNT--ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
E ++LEE L EL+ N ML E++ L + D V + +L
Sbjct: 126 AEAREKETKALSLARALEEALEAKEELERTNKMLK---AEMEDLVSSKDDVGKNVHELEK 182
Query: 418 CVKNLEEALEKEKFAHDSTKSNI--TELNKRIQSVNDETLLLTQERDL-LKSKVNEERSR 474
+ LE +E+ K + + + TE K VN + L ERDL + + NEE+ R
Sbjct: 183 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 242
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
+++QL E + + + K+ K L +L+ EL+ + + + ++
Sbjct: 243 --QLQRQLHEYETELEDERKQRALAAAAKKKLEG--DLKDLELQADSAIKGREEAIKHVR 298
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSF--NKQILRIEEQHKLEIN---VLEEKQREEIK 589
+ Q Q+ +RE+E DAR + I + N++ + E +++ E+ R++
Sbjct: 299 KLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 357
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L + +LA+ + ++ ++RR A+L L+
Sbjct: 358 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 396
Score = 47.2 bits (107), Expect = 2e-04
Identities = 57/266 (21%), Positives = 118/266 (44%), Gaps = 23/266 (8%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
NE+ ++ L + +N+ LS+ K++ + + K+ ++NL + E++
Sbjct: 3 NEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 62
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
A+D + N+ Q ++D + L +R L+ + ++R +Q L E++N S
Sbjct: 63 AAYDKLEKT---KNRLQQELDDLVVDLDNQRQLVSNLEKKQRK----FDQLLAEEKNISS 115
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + D + E + +K + LE+A+ AK +E + + EME+
Sbjct: 116 KYADERDRAEAEAR--------EKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 166
Query: 551 ARLKEN---NIVD-SFNKQILRIE-EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGL 604
K++ N+ + +K+ L + E+ K ++ LE E Q E RL++ A K G
Sbjct: 167 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQ 225
Query: 605 LESKVECQRRRRGETAARLHAALQAH 630
E ++ + + E +L L +
Sbjct: 226 FERDLQARDEQNEEKRRQLQRQLHEY 251
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 326 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 385
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 386 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 443
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 444 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 501
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 502 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 558
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 559 EATE--SNEAMGREVNALKS 576
Score = 39.9 bits (89), Expect = 0.028
Identities = 62/304 (20%), Positives = 127/304 (41%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 234 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 287
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + + + + + +E++ + + D + K+ K+LE L + E
Sbjct: 288 KGREEAIK-HVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 346
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 347 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 402
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 403 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 457
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 458 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 509
Query: 611 CQRR 614
+R+
Sbjct: 510 DERK 513
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 54.4 bits (125), Expect = 1e-06
Identities = 74/339 (21%), Positives = 156/339 (46%), Gaps = 29/339 (8%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQ 370
+ L++ ++R ++ L+ ++ +++N R + + +KK F+ L + +++ Y D+ + +
Sbjct: 66 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 125
Query: 371 NE-----------KKSLEEQLNT--ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
E ++LEE L EL+ N ML E++ L + D V + +L
Sbjct: 126 AEAREKETKALSLARALEEALEAKEELERTNKMLK---AEMEDLVSSKDDVGKNVHELEK 182
Query: 418 CVKNLEEALEKEKFAHDSTKSNI--TELNKRIQSVNDETLLLTQERDL-LKSKVNEERSR 474
+ LE +E+ K + + + TE K VN + L ERDL + + NEE+ R
Sbjct: 183 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 242
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
+++QL E + + + K+ K L +L+ EL+ + + + ++
Sbjct: 243 --QLQRQLHEYETELEDERKQRALAAAAKKKLEG--DLKDLELQADSAIKGREEAIKHVR 298
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSF--NKQILRIEEQHKLEIN---VLEEKQREEIK 589
+ Q Q+ +RE+E DAR + I + N++ + E +++ E+ R++
Sbjct: 299 KLQAQMKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQAD 357
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
L + +LA+ + ++ ++RR A+L L+
Sbjct: 358 LEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 396
Score = 47.2 bits (107), Expect = 2e-04
Identities = 57/266 (21%), Positives = 118/266 (44%), Gaps = 23/266 (8%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
NE+ ++ L + +N+ LS+ K++ + + K+ ++NL + E++
Sbjct: 3 NEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 62
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
A+D + N+ Q ++D + L +R L+ + ++R +Q L E++N S
Sbjct: 63 AAYDKLEKT---KNRLQQELDDLVVDLDNQRQLVSNLEKKQRK----FDQLLAEEKNISS 115
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + D + E + +K + LE+A+ AK +E + + EME+
Sbjct: 116 KYADERDRAEAEAR--------EKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 166
Query: 551 ARLKEN---NIVD-SFNKQILRIE-EQHKLEINVLE-EKQREEIKLYRLQLAQAAEKLGL 604
K++ N+ + +K+ L + E+ K ++ LE E Q E RL++ A K G
Sbjct: 167 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK-GQ 225
Query: 605 LESKVECQRRRRGETAARLHAALQAH 630
E ++ + + E +L L +
Sbjct: 226 FERDLQARDEQNEEKRRQLQRQLHEY 251
Score = 44.4 bits (100), Expect = 0.001
Identities = 53/260 (20%), Positives = 116/260 (44%), Gaps = 22/260 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQ 370
+ ++ K+LE + +++ A+ A+K+ EL +L + QD+ ++L+
Sbjct: 326 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 385
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
LEE+L E N+ M S++ ++ E + + ++ + LE++
Sbjct: 386 ARIAQLEEELEEEQGNMEAM-SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ- 443
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ +S + E+ ++S T+ + + L+ +V +E + L +K +
Sbjct: 444 --NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKL 501
Query: 490 SEVLKKCDFLDNEVKTLRQHLE-LQKNELKC-HYQKQLEDA------VLAKLQEFQEQLD 541
E+L + +++E K Q+ E +K + ++QLE+A + A ++ Q +LD
Sbjct: 502 KEILLQ---VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELD 558
Query: 542 RAEREMENDARLKENNIVDS 561
A N+A +E N + S
Sbjct: 559 EATE--SNEAMGREVNALKS 576
Score = 39.9 bits (89), Expect = 0.028
Identities = 62/304 (20%), Positives = 127/304 (41%), Gaps = 27/304 (8%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + R+ L++ + E E +D +K+ + + K L D +D Q +
Sbjct: 234 DEQNEEKRRQLQRQLHEYET---ELEDERKQRALAAAAKKK---LEGDLKDLELQADSAI 287
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK--EKF 431
K EE + + + + + +E++ + + D + K+ K+LE L + E
Sbjct: 288 KGREEAIK-HVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 346
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
A +L K + + +E R+ L+ + +R A +E++L E+Q
Sbjct: 347 AAAERARKQADLEK--EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM-- 402
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMEND 550
+ + + V+ Q E NEL Q ++ +L+ ++L EME
Sbjct: 403 -----EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGA 457
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
+ K + + + +I ++EEQ +E++ RE+ + L Q +KL + +VE
Sbjct: 458 VKSKFKSTIAALEAKIAQLEEQ-------VEQEAREK-QAATKSLKQKDKKLKEILLQVE 509
Query: 611 CQRR 614
+R+
Sbjct: 510 DERK 513
>AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein protein.
Length = 2319
Score = 54.4 bits (125), Expect = 1e-06
Identities = 76/328 (23%), Positives = 147/328 (44%), Gaps = 35/328 (10%)
Query: 309 LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ 368
L+ L ED K + + E E R+ A DA + + L + L YQ +C Q
Sbjct: 1064 LSEMLKSLEDLKLKNTKIEVLE-EELRL-ARDANSENCNKNKFLDQNLQ---KYQAECSQ 1118
Query: 369 LQNEKKSLEE-QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV---KNLEE 424
+ + SLEE + ELD + N DK +KE + + RL ++ D K++E+
Sbjct: 1119 FKAKLASLEELKRQAELDGKSAK-QNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVED 1177
Query: 425 ALEKEKFAHDSTKS--NITELNKRIQSVNDETLLLTQERDLLKSKV--NEERSRCAVIEQ 480
+++K +D + + N Q + E + +E ++ + +V EE +R E
Sbjct: 1178 RFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYEN 1237
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
+L + N+ E +C + E ++L +++ + + A+LQ +++L
Sbjct: 1238 ELAKASNRIQESKNQCTQVVQERESLLVKIKVLEQDK-------------ARLQRLEDEL 1284
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE------EKQREEIKLYRLQ 594
+RA+ +E + R+K+ ++ +QI Q K + + E E +RE+ + +
Sbjct: 1285 NRAKSTLEAETRVKQR--LECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 1342
Query: 595 LAQAAEKLGLLESKVECQRRRRGETAAR 622
L E+L ++E + RR+ E + R
Sbjct: 1343 LRSEIERLQAEIKRIEERCRRKLEDSTR 1370
Score = 50.0 bits (114), Expect = 3e-05
Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 4/169 (2%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
KA+++ E+E RV+ + + +E+EL K + + +++C Q+ E++SL ++
Sbjct: 1209 KAIKEKEYEIERLRVLLQEEGTRKREYENELAKASNRIQESKNQCTQVVQERESLLVKIK 1268
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK-NLEEALEKEKFAHDSTKSNI 440
L+ L + E++ K + R+ KQ +C K ++ L + K + + I
Sbjct: 1269 V-LEQDKARLQRLEDELNRAKSTLEAETRV-KQRLECEKQQIQNDLNQWKTQYSRKEEAI 1326
Query: 441 TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC-AVIEQQLCEKQNQ 488
++ + E L E + L++++ RC +E E Q+Q
Sbjct: 1327 RKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQ 1375
Score = 36.7 bits (81), Expect = 0.26
Identities = 51/254 (20%), Positives = 122/254 (48%), Gaps = 20/254 (7%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL-YKTLD 357
I +L E RLT ++ E R RK++E + +N D QK + L ++ L+
Sbjct: 1151 IKELNEKITRLTYEIED-EKRRRKSVEDRFDQQKNDY---DQLQKARQCEKENLGWQKLE 1206
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
++K +++ + L+E+ + + N L+ I K V++ + L
Sbjct: 1207 SEKAIKEKEYEIERLRVLLQEEGTRKREYENE-LAKASNRIQESKNQCTQVVQERESLLV 1265
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLL---LTQERDLLKSKVNEERSR 474
+K LE+ + + D ELN+ ++ ET + L E+ +++ +N+ +++
Sbjct: 1266 KIKVLEQDKARLQRLED-------ELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQ 1318
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
+ E+ + + +++ + ++ + L +E++ L+ E+++ E +C +++LED+
Sbjct: 1319 YSRKEEAIRKIESEREKSEREKNSLRSEIERLQA--EIKRIEERC--RRKLEDSTRETQS 1374
Query: 535 EFQEQLDRAEREME 548
+ + + R +RE++
Sbjct: 1375 QLETERSRYQREID 1388
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 54.4 bits (125), Expect = 1e-06
Identities = 69/324 (21%), Positives = 156/324 (48%), Gaps = 18/324 (5%)
Query: 307 LRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDY---Q 363
L L L++ + R+ E+ ++E R A ++ E E + +L + Q
Sbjct: 426 LELEKRLEKQRELERQREEERRKDIER-REAAKQELERQRRLEWERIRRQELLNQKNREQ 484
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC----V 419
++ +L ++KK+L +L L+ + +S + +++ + K+ T + + + D +
Sbjct: 485 EEIVRLNSKKKNLHLELEA-LNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEI 543
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
K L++ L++ + LN+RI+++ LL K E+ C ++
Sbjct: 544 KQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTP-DSGVSLLHKKSLEKEELCQRLK 602
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
+QL + + + L + D +N++K LR+ Q+ L+ Y +++ L +++ + +
Sbjct: 603 EQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLY--KIKRDKLKEIERKRLE 660
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
L ++++E++A K ++ K+ LR EE+ K + + EEK +E+I + + +A
Sbjct: 661 L-MQKKKLEDEAARKAKQGKENLWKENLRKEEEEK-QKRLQEEKTQEKI---QEEERKAE 715
Query: 600 EKLGLLESKVECQRRRRGETAARL 623
EK + ++ + ++R ETA+ L
Sbjct: 716 EKQRKDKDTLKAEEKKR-ETASVL 738
Score = 31.9 bits (69), Expect = 7.4
Identities = 25/108 (23%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 514 KNELKCHYQK---QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE 570
+++ K +Y++ +LE A +++ Q + +R ++ + + K+ + + K+ L +E
Sbjct: 370 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 429
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +LE E+QREE + ++ +AA++ + ++E +R RR E
Sbjct: 430 K--RLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQE 475
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
+ L+ A+ Y+ ++L N + L E +++ + KD EI LK+N + + +K
Sbjct: 731 RLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHK 790
Query: 414 QLTDCV-------KNLEEALEKEKFAHDSTKSNIT----ELNKRIQSVNDETLL--LTQE 460
+ D + K L + + K++ + K + EL+K Q++ +L +E
Sbjct: 791 ETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEE 850
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV-----LKKCDFLDNEVKTLRQHLELQKN 515
+D + EE + ++L E+Q++ + V L L +EV L E +
Sbjct: 851 KDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEE 910
Query: 516 ELKCHYQKQLED------AVLAKLQEFQEQLD--RAEREMENDAR----LKENNIVDSFN 563
E+K H+QK +ED +L LQE ++++D R + E N L+++ + S
Sbjct: 911 EIK-HHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQ 969
Query: 564 KQILRIEEQ---HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K I +I+ Q + +I +E K+ L + +EK L SK E +R +G
Sbjct: 970 KTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDL--SKAETERLVKG 1024
Score = 48.8 bits (111), Expect = 6e-05
Identities = 68/301 (22%), Positives = 145/301 (48%), Gaps = 38/301 (12%)
Query: 360 HDYQD-KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
H+ D + KQL+ EK+ + ++L E D +++ K ++ EN+ + N+ L
Sbjct: 1388 HEQTDSEIKQLK-EKQDVLQKLLKEKD---LLIKAKSDQLLSSNENFTNKVNENELLRQA 1443
Query: 419 VKNLEEAL------------EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS 466
V NL+E + E EK ++ + TE + +Q N + ++ +E++
Sbjct: 1444 VTNLKERILILEMDIGKLKGENEKIV-ETYRGKETEY-QALQETNMKFSMMLREKEF--- 1498
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE----LKCHYQ 522
+ + + + EQ L EK+ + L + L N VK++++ + + E + Q
Sbjct: 1499 ECHSMKEKALAFEQLLKEKEQGKTGELNQ---LLNAVKSMQEKTVVFQQERDQVMLALKQ 1555
Query: 523 KQLEDAVLA-KLQEFQEQLDRAEREMENDARLKENNI--VDSFNKQILRIEEQH---KLE 576
KQ+E+ L ++Q +++ R+ +E+E RL+ + + DS+ ++ L E++ + +
Sbjct: 1556 KQMENTALQNEVQRLRDKEFRSNQELE---RLRNHLLESEDSYTREALAAEDREAKLRKK 1612
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALR 636
+ VLEEK QA+ ++ L+ ++ ++R ETA +L + + ++AL
Sbjct: 1613 VTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALS 1672
Query: 637 I 637
+
Sbjct: 1673 L 1673
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/294 (19%), Positives = 131/294 (44%), Gaps = 17/294 (5%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE-KKSLEEQLNTE 383
+K+ +VEN + +Q+ + E + + +++ +++NE +SL + N+
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSN 638
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITEL 443
+ +L ++ E+ LK+N + +LN+ L +++ EK A + + + E
Sbjct: 639 FKDT--LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEEC 696
Query: 444 NKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+ N +L + LK + E + +++L E+ N+ + +++ N +
Sbjct: 697 ---LAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARN-L 752
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
T LE ++ +K + +K +E A L K E + + +++ + + ++ + N
Sbjct: 753 NTSALQLE-HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLIN 811
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K+ + IE ++ K +EE+ Y +QA K +L +E + R G
Sbjct: 812 KKEIFIE-----KLKERSSKLQEELDKY----SQALRKNEILRQTIEEKDRSLG 856
Score = 43.6 bits (98), Expect = 0.002
Identities = 70/332 (21%), Positives = 143/332 (43%), Gaps = 24/332 (7%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL+ + ++ ++++ E A + EV + DA+ + S L + LA
Sbjct: 358 SKLQPSAVKQSDTM--TEKERILAQSASVEEVFRLQQALSDAENEIMRLSS-LNQDNSLA 414
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
D +++ +K + L+ E + + + L + E +V+K + L+ +L D
Sbjct: 415 EDNLKLKMRIEVLEKE-KSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLR 473
Query: 420 KNL---EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
NL E+ L + ++ + I EL+++ Q +L+ +D L + NE S +
Sbjct: 474 LNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILI---KDQLSKQQNEGDSIIS 530
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNELKCHYQKQLEDAV---- 529
++Q L +++ + ++ + E+ ++ L E+ N+L QK LED V
Sbjct: 531 KLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQK-LEDKVENLV 589
Query: 530 --LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK--QILRIEEQHKLEINVLEEKQR 585
L K QE + + E++ R E + N+ Q L + + +L+E++
Sbjct: 590 DQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREA 649
Query: 586 E--EIKLYRLQLAQAAEKLGLLESKVECQRRR 615
E +K +L Q E L + V+ + +
Sbjct: 650 EVRNLKQNLSELEQLNENLKKVAFDVKMENEK 681
Score = 41.5 bits (93), Expect = 0.009
Identities = 65/258 (25%), Positives = 119/258 (46%), Gaps = 30/258 (11%)
Query: 319 RHRKAL---EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD-KCKQLQNEKK 374
RHR+ L E+ I E+EN Q + E++L K ++ Q + +++++ KK
Sbjct: 253 RHREELSDYEERIEELENLL-----QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKK 307
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
EQL ++ ++N LS+ + + D+L+ + + +Q+ + +NL+ LE K
Sbjct: 308 M--EQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLK--LECSKLQPS 363
Query: 435 STKSNITELNK-RI--QSVNDETLLLTQ------ERDLLK-SKVNEERSRCAVIEQQLCE 484
+ K + T K RI QS + E + Q E ++++ S +N++ S + E L
Sbjct: 364 AVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNS---LAEDNL-- 418
Query: 485 KQNQCSEVL-KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLDR 542
K EVL K+ L E + L+ L NE + D L ++L + + L+
Sbjct: 419 KLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEA 478
Query: 543 AEREMENDARLKENNIVD 560
E+E+ KE I +
Sbjct: 479 KEQELNQSISEKETLIAE 496
Score = 40.7 bits (91), Expect = 0.016
Identities = 45/236 (19%), Positives = 97/236 (41%), Gaps = 17/236 (7%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL---- 376
++ L+ E E V ++ ++ SH ++E +K +D+ + +LQ+E K L
Sbjct: 1088 QQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRF 1147
Query: 377 ----EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF- 431
++ + N++ ++ KD EID L + T++ + + T N + +F
Sbjct: 1148 ESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQ--TSSTGNEAGGVNSHQFE 1205
Query: 432 ----AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
D K + ++ + Q V + E L+ ++++ +++ V + Q
Sbjct: 1206 ELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQV 1265
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
+ +++ + NE K EL + + +D +L KL QL A
Sbjct: 1266 DYTGLIQ--SYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSA 1319
Score = 39.1 bits (87), Expect = 0.049
Identities = 50/250 (20%), Positives = 110/250 (44%), Gaps = 19/250 (7%)
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKEN----YDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
E L EL+ + L KD I L+EN D++ ++ + + +++ K
Sbjct: 1343 ELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQ 1402
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQ-------ERDLLKSKVNEERSRCAVIEQQLCEKQ 486
D + + E + I++ +D+ L + E +LL+ V + R ++E + + +
Sbjct: 1403 DVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLK 1462
Query: 487 NQCSEVLKKCDFLDNEVKTLRQ-----HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
+ ++++ + E + L++ + L++ E +CH K+ A L+E ++
Sbjct: 1463 GENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKT 1522
Query: 542 RAEREMENDAR-LKENNIV-DSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRLQLAQA 598
++ N + ++E +V Q++ +Q ++E L+ E QR K +R
Sbjct: 1523 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1582
Query: 599 AEKLGLLESK 608
+ LLES+
Sbjct: 1583 RLRNHLLESE 1592
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/302 (24%), Positives = 134/302 (44%), Gaps = 38/302 (12%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
I L +A LRL ++R H K +E EVE R QKK E + L
Sbjct: 1578 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR---QSCQKKLKQME------VQL 1628
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+Y+DK K L+ EK+ LE +L T D VN +K + + ++ + + D
Sbjct: 1629 EEEYEDKQKVLR-EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1687
Query: 419 VKN----------LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+KN L+ LE+ +F + + I+ ++ + + + + L+ ++
Sbjct: 1688 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1747
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLED 527
+ + I+ +L E Q +E++KK ++ + +L Q N+L Q QLE+
Sbjct: 1748 SRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLAQINDL----QAQLEE 1798
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
A K QE QE+L + ++E E ++VD K ++ +E E+ E +R +
Sbjct: 1799 ANKEK-QELQEKLQALQSQVE----FLEQSMVD---KSLVSRQEAKIRELETRLEFERTQ 1850
Query: 588 IK 589
+K
Sbjct: 1851 VK 1852
Score = 50.0 bits (114), Expect = 3e-05
Identities = 64/308 (20%), Positives = 133/308 (43%), Gaps = 30/308 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKT 345
+ +D K++A SK A L+ N L+ +E KA + M E+E+ + DD K
Sbjct: 1683 LMLDHLKNSAPSKREIAQLK--NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1740
Query: 346 SHFESELYKTLDLAHDYQDKCKQ-------LQNEKKSLEEQLNTELDNVN---VMLSNKD 395
+ E +L + ++ Q++ ++ L + K+ Q + +L +N L +
Sbjct: 1741 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1800
Query: 396 KEIDVLKENYDTVMR----LNKQLTD--CVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
KE L+E + L + + D V E + + + + ++ + L
Sbjct: 1801 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1860
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + LT+ERD + N E+ + +++QL + + + E+ +K + E +
Sbjct: 1861 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARK----EAEASRKKHE 1916
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
LE+ L+ Q D LA + + E EME+D + ++++S + +
Sbjct: 1917 LEMDLESLEAANQSLQADLKLA-FKRIGDLQAAIEDEMESD---ENEDLINSLQDMVTKY 1972
Query: 570 EE-QHKLE 576
++ ++KLE
Sbjct: 1973 QKRKNKLE 1980
Score = 40.3 bits (90), Expect = 0.021
Identities = 47/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN---QCSEV 492
++ I ++ IQ + + +ER+ L+ + SR + + +L +++N S++
Sbjct: 1265 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1324
Query: 493 L--KKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
L + + L + E+K L+ + K +++ + ++ +A L + E ++D + +
Sbjct: 1325 LDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARLIRAAEINGEVD--DDDAG 1381
Query: 549 NDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ RLK V F K+ L+ E + KLE+ ++Q E +L LQ + L +
Sbjct: 1382 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER-RLGDLQADSEESQRALQQ 1440
Query: 607 SKVECQRRRRGETAARLHAALQAHWRHAL 635
K +CQR +LH Q H L
Sbjct: 1441 LKKKCQRLTAELQDTKLHLEGQQVRNHEL 1469
Score = 40.3 bits (90), Expect = 0.021
Identities = 52/243 (21%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN---KDKEIDVLKENYDTVMRLNK 413
DL D ++ + LQ KK + +L EL + + L ++ E++ + +D+ +
Sbjct: 1426 DLQADSEESQRALQQLKKKCQ-RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1484
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
+ K E L++EK D + L ++++ + + TQ+ L++++ +
Sbjct: 1485 EEAQREKLQREKLQREK---DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD--- 1538
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
I Q + + ++V K+ L+ +VK + L+ Q ++ LE A L
Sbjct: 1539 ----ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ-----MLEQAKLRLE 1589
Query: 534 QEFQEQLDRAEREMEN-DARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E + +EME+ D ++E + + +++EE+++ + VL EK+ E KL
Sbjct: 1590 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1649
Query: 591 YRL 593
L
Sbjct: 1650 ATL 1652
Score = 39.9 bits (89), Expect = 0.028
Identities = 74/331 (22%), Positives = 142/331 (42%), Gaps = 20/331 (6%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R L + R L+ +E +V + +KK F+SEL + + A + + +
Sbjct: 1436 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1495
Query: 368 QLQNEKKSLEEQ---LNTELDNVNVMLSN-KDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+LQ EK L + L +L+ ++ ++ K + + E D + +K K +
Sbjct: 1496 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1555
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE-RSRCAVIEQ-- 480
+ + E D + + E IQ + L L E + ++ ++E SR +E+
Sbjct: 1556 QLRDLEAKVKDQ-EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1614
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
Q C+K+ + EV + ++ D + K LR+ EL+ Q D K ++ L
Sbjct: 1615 QSCQKKLKQMEVQLEEEYEDKQ-KVLREKRELEGKLATLSDQVNRRDFESEK--RLRKDL 1671
Query: 541 DRAEREMENDARLKENNIVDS--FNKQILRIEEQ-HKLEIN----VLEEKQRE-EIKLYR 592
R + + DA+L +++ +S ++I +++ Q + E V K E EI+
Sbjct: 1672 KRT-KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1730
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARL 623
LQ+ A+ LE ++ +R + E RL
Sbjct: 1731 LQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1761
Score = 32.7 bits (71), Expect = 4.2
Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 12/229 (5%)
Query: 377 EEQLNT---ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
EEQ+ E+ + L +KE + L+ N D + +LT + + E
Sbjct: 1266 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1325
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER-SRCAVIEQQLCEKQNQCSEV 492
D+ + K ++ + + L ++ ++++ +V E R R A I ++ + + E
Sbjct: 1326 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEV-DDDDAGGEW 1384
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
K + EV ++ L+ Q+ E K ++Q + + +L + Q + ++R ++ +
Sbjct: 1385 RLKYERAVREVDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQ-QLK 1442
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
K + L +E Q ++ + LE+KQR + +L+QA E+
Sbjct: 1443 KKCQRLTAELQDTKLHLEGQ-QVRNHELEKKQRR----FDSELSQAHEE 1486
>BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein
protein.
Length = 1694
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
+ L+ A+ Y+ ++L N + L E +++ + KD EI LK+N + + +K
Sbjct: 446 RLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHK 505
Query: 414 QLTDCV-------KNLEEALEKEKFAHDSTKSNIT----ELNKRIQSVNDETLL--LTQE 460
+ D + K L + + K++ + K + EL+K Q++ +L +E
Sbjct: 506 ETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEE 565
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV-----LKKCDFLDNEVKTLRQHLELQKN 515
+D + EE + ++L E+Q++ + V L L +EV L E +
Sbjct: 566 KDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEE 625
Query: 516 ELKCHYQKQLED------AVLAKLQEFQEQLD--RAEREMENDAR----LKENNIVDSFN 563
E+K H+QK +ED +L LQE ++++D R + E N L+++ + S
Sbjct: 626 EIK-HHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQ 684
Query: 564 KQILRIEEQ---HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K I +I+ Q + +I +E K+ L + +EK L SK E +R +G
Sbjct: 685 KTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDL--SKAETERLVKG 739
Score = 51.6 bits (118), Expect = 9e-06
Identities = 69/281 (24%), Positives = 135/281 (48%), Gaps = 27/281 (9%)
Query: 349 ESELYKTLDLAHDYQD-KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E++L K ++ Q + +++++ KK EQL ++ ++N LS+ + + D+L+ +
Sbjct: 25 ETDLSKIYEMQKTIQVLQIEKVESTKKM--EQLEDKIKDINKKLSSAENDRDILRREQEQ 82
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK-RI--QSVNDETLLLTQERDLL 464
+ +Q+ + +NL+ LE K + K + T K RI QS + E + Q+ L
Sbjct: 83 LNVEKRQIMEECENLK--LECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQ--AL 138
Query: 465 KSKVNEERSRCAVIEQQL---CEKQNQCSEVLKKC---DF-LDNEVKTLRQHLELQKNEL 517
NE ++ +++L K N EV+K D LD+E+ LR +LE ++ EL
Sbjct: 139 SDAENEIMRLSSLNQEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 198
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREM--ENDARLKENNIVDSFNKQILRIEEQHKL 575
+ ++ ++A+++E Q A + M D K+ N DS ++ + K
Sbjct: 199 NQSISE--KETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKK 256
Query: 576 EINVLEEKQRE---EIKLYRLQLAQ---AAEKLGLLESKVE 610
++ LE+ + + E+ + + +L Q A L L + K+E
Sbjct: 257 RVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLE 297
Score = 48.4 bits (110), Expect = 8e-05
Identities = 68/301 (22%), Positives = 144/301 (47%), Gaps = 38/301 (12%)
Query: 360 HDYQD-KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
H+ D + KQL+ EK+ + ++L E D +++ K ++ EN+ + N+ L
Sbjct: 1103 HEQTDSEIKQLK-EKQDVLQKLLKEKD---LLIKAKSDQLLSSNENFTNKVNENELLRQA 1158
Query: 419 VKNLEEAL------------EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS 466
V NL+E + E EK ++ + TE + +Q N + ++ +E++
Sbjct: 1159 VTNLKERILILEMDIGKLKGENEKIV-ETYRGKETEY-QALQETNMKFSMMLREKEF--- 1213
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE----LKCHYQ 522
+ + + + EQ L EK+ + L + L N VK++++ + + E + Q
Sbjct: 1214 ECHSMKEKALAFEQLLKEKEQGKTGELNQ---LLNAVKSMQEKTVVFQQERDQVMLALKQ 1270
Query: 523 KQLEDAVLAK-LQEFQEQLDRAEREMENDARLKENNI--VDSFNKQILRIEEQH---KLE 576
KQ+E+ L +Q +++ R+ +E+E RL+ + + DS+ ++ L E++ + +
Sbjct: 1271 KQMENTALQNVVQRLRDKEFRSNQELE---RLRNHLLESEDSYTREALAAEDREAKLRKK 1327
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALR 636
+ VLEEK QA+ ++ L+ ++ ++R ETA +L + + ++AL
Sbjct: 1328 VTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALS 1387
Query: 637 I 637
+
Sbjct: 1388 L 1388
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/294 (19%), Positives = 131/294 (44%), Gaps = 17/294 (5%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE-KKSLEEQLNTE 383
+K+ +VEN + +Q+ + E + + +++ +++NE +SL + N+
Sbjct: 294 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSN 353
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITEL 443
+ +L ++ E+ LK+N + +LN+ L +++ EK A + + + E
Sbjct: 354 FKDT--LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEEC 411
Query: 444 NKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+ N +L + LK + E + +++L E+ N+ + +++ N +
Sbjct: 412 ---LAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARN-L 467
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
T LE ++ +K + +K +E A L K E + + +++ + + ++ + N
Sbjct: 468 NTSALQLE-HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLIN 526
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K+ + IE ++ K +EE+ Y +QA K +L +E + R G
Sbjct: 527 KKEIFIE-----KLKERSSKLQEELDKY----SQALRKNEILRQTIEEKDRSLG 571
Score = 41.1 bits (92), Expect = 0.012
Identities = 45/236 (19%), Positives = 98/236 (41%), Gaps = 17/236 (7%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL---- 376
++ L+ E E V ++ ++ SH ++E +K +D+ + +LQ+E K L
Sbjct: 803 QQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRF 862
Query: 377 ----EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF- 431
++ + N++ ++ KD EID L + T++ + + T N + +F
Sbjct: 863 ESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQ--TSSTGNEAGGVNSNQFE 920
Query: 432 ----AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
D+ K + ++ + Q V + E L+ ++++ +++ V + Q
Sbjct: 921 ELLQERDTLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQV 980
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
+ +++ + NE K EL + + +D +L KL QL A
Sbjct: 981 DYTGLIQ--SYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSA 1034
Score = 39.5 bits (88), Expect = 0.037
Identities = 60/269 (22%), Positives = 113/269 (42%), Gaps = 23/269 (8%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNL 422
Q +NE L EL + L+N E +V+K + L+ +L D NL
Sbjct: 135 QQALSDAENEIMRLSSLNQEELQMSLLKLNN---EYEVIKSTATRDISLDSELHDLRLNL 191
Query: 423 ---EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
E+ L + ++ + I EL+++ Q +L+ +D L + NE S + ++
Sbjct: 192 EAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILI---KDQLSKQQNEGDSIISKLK 248
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL---ELQKNELKCHYQKQLEDAV------L 530
Q L +++ + ++ + E+ ++ L E+ N+L QK LED V L
Sbjct: 249 QDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQK-LEDKVENLVDQL 307
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNK--QILRIEEQHKLEINVLEEKQRE-- 586
K QE + + E++ R E + N+ Q L + + +L+E++ E
Sbjct: 308 NKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVR 367
Query: 587 EIKLYRLQLAQAAEKLGLLESKVECQRRR 615
+K +L Q E L + V+ + +
Sbjct: 368 NLKQNLSELEQLNENLKKVAFDVKMENEK 396
Score = 37.1 bits (82), Expect = 0.20
Identities = 45/230 (19%), Positives = 100/230 (43%), Gaps = 26/230 (11%)
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKEN----YDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
E L EL+ + L KD I L+EN D++ ++ + + +++ K
Sbjct: 1058 ELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQ 1117
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQ-------ERDLLKSKVNEERSRCAVIEQQLCEKQ 486
D + + E + I++ +D+ L + E +LL+ V + R ++E + + +
Sbjct: 1118 DVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLK 1177
Query: 487 NQCSEVLKKCDFLDNEVKTLRQ-----HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
+ ++++ + E + L++ + L++ E +CH K+ K F++ L
Sbjct: 1178 GENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKE-------KALAFEQLL- 1229
Query: 542 RAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E+E L + N V S ++ + +++ + L++KQ E L
Sbjct: 1230 -KEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTAL 1278
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 54.0 bits (124), Expect = 2e-06
Identities = 64/302 (21%), Positives = 139/302 (46%), Gaps = 25/302 (8%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE--EQLNT 382
++M E F+ + D+ K + + K + L + D Q+Q E + L E+
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L + L K KE+ E+ + + N +LT + LE+ + K D + + +
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEI---NAELTAKKRKLEDECSELKKDIDDLELTLAK 969
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
+ K + ++ LT+E + ++E ++ ++ L E Q + L+ +++
Sbjct: 970 VEKEKHATENKVKNLTEEM----AGLDETIAKLTKEKKALQEAHQQTLDDLQA---EEDK 1022
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
V TL K ++K Q + L + ++ + L+RA+R++E D +L + +I+D
Sbjct: 1023 VNTLT------KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076
Query: 563 NKQILRIEEQHKLEINV------LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
N++ E+ K E + +E++Q I+L + ++ + ++ LE ++E +R R
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK-KIKELQARIEELEEEIEAERASR 1135
Query: 617 GE 618
+
Sbjct: 1136 AK 1137
Score = 52.8 bits (121), Expect = 4e-06
Identities = 63/290 (21%), Positives = 126/290 (43%), Gaps = 14/290 (4%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT 382
+E++ E+E R A+K+ S EL + + + Q++ KK E
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK----FAHDSTKS 438
D L ++ + K++ D+V L +Q+ D ++ +++ LEKEK D S
Sbjct: 1181 RRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF 498
N+ ++K ++ L + LKSK E++ + Q Q + E ++ D
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 499 LDNEVKTL---RQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLD--RAEREMENDA 551
+ V L +Q Q ELK ++++ ++A+ LQ + D R + E E ++
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 552 RLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+ + + N ++ + +++ + + ++ EE K Q QAAE+
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDA-IQRTEELEEAKKKLAQRLQAAEE 1408
Score = 44.8 bits (101), Expect = 0.001
Identities = 62/308 (20%), Positives = 131/308 (42%), Gaps = 32/308 (10%)
Query: 310 TNSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDK 365
TN+ A D+ ++ +K++ E E + +QK+ +EL+K + + D+
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 366 CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA 425
+ L+ E K+L++ E+ ++ ++ K I L+ ++ KQ+ L+ A
Sbjct: 1501 LETLKRENKNLQQ----EISDLTEQIAEGGKRIHELE-------KIKKQVEQEKCELQAA 1549
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-----LLKSKVNEERSRCAVIEQ 480
LE+ + + + + I + + V E E+D L ++ + S + ++
Sbjct: 1550 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDA 1609
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
++ +N + KK + NE++ H E +Y+ L++ Q L
Sbjct: 1610 EI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN-----TQGILKDTQIHL 1663
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
D A R E+ LKE + +L+ E + E+ E+ K+ +L A+E
Sbjct: 1664 DDALRSQED---LKEQLAMVERRANLLQAEIE---ELRATLEQTERSRKIAEQELLDASE 1717
Query: 601 KLGLLESK 608
++ LL ++
Sbjct: 1718 RVQLLHTQ 1725
Score = 41.5 bits (93), Expect = 0.009
Identities = 41/192 (21%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 392 SNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK---RIQ 448
S EID L N +TV + L + LE+ L + K + + I +L R+Q
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 449 SVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
+ + E E++ L S+++ + QQ+ E + Q E +K + L + +++ R
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQ---AFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK--QI 566
+L + + + + + E + L + ++ + + E DA + + ++ K Q
Sbjct: 1345 DCDLLREQYEEEQESKAE--LQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402
Query: 567 LRIEEQHKLEIN 578
L+ E+H +N
Sbjct: 1403 LQAAEEHVEAVN 1414
Score = 40.3 bits (90), Expect = 0.021
Identities = 60/259 (23%), Positives = 103/259 (39%), Gaps = 27/259 (10%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E E+ LAH Q ++ EE+ ++ + + LS + E+ + Y+T
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE-LQRALSKANTEVAQWRTKYET- 1383
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+ LEEA +K + + ++ +N + S+ L E + L V
Sbjct: 1384 -----DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1438
Query: 469 NEERSRCAVIEQQ-------LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ CA ++++ L E + +C E + + E ++L L KN +
Sbjct: 1439 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYE-ES 1497
Query: 522 QKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN-VL 580
QLE QE D E+ E R+ E ++ KQ+ EQ K E+ L
Sbjct: 1498 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE---LEKIKKQV----EQEKCELQAAL 1550
Query: 581 EEK----QREEIKLYRLQL 595
EE + EE K+ R+QL
Sbjct: 1551 EEAEASLEHEEGKILRIQL 1569
Score = 38.7 bits (86), Expect = 0.065
Identities = 53/301 (17%), Positives = 124/301 (41%), Gaps = 23/301 (7%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++ L+ + E + + +++ E L + L
Sbjct: 991 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Query: 359 AHDYQDKCKQLQNEKKSLEEQL---NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E + E ++ L K+ EI L+ + L QL
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQL 1110
Query: 416 TDCVKNL-------EEALEKEKFAHDSTKSNITELNKRIQSVNDETL----LLTQERDLL 464
+K L EE +E E+ + + ++L++ ++ +++ + + ++
Sbjct: 1111 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1170
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQ 524
K + E + +E+ + + + + KK D+ + Q LQ+ + K +K
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAATLRKK--HADSVAELGEQIDNLQRVKQKLEKEKS 1228
Query: 525 LEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
+ L E + +A+ +E R E+ + + +K+ EEQ +L ++ ++
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE----EEQQRLINDLTAQRG 1284
Query: 585 R 585
R
Sbjct: 1285 R 1285
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/302 (24%), Positives = 134/302 (44%), Gaps = 38/302 (12%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
I L +A LRL ++R H K +E EVE R QKK E + L
Sbjct: 1107 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR---QSCQKKLKQME------VQL 1157
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+Y+DK K L+ EK+ LE +L T D VN +K + + ++ + + D
Sbjct: 1158 EEEYEDKQKVLR-EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1216
Query: 419 VKN----------LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+KN L+ LE+ +F + + I+ ++ + + + + L+ ++
Sbjct: 1217 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1276
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLED 527
+ + I+ +L E Q +E++KK ++ + +L Q N+L Q QLE+
Sbjct: 1277 SRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLAQINDL----QAQLEE 1327
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
A K QE QE+L + ++E E ++VD K ++ +E E+ E +R +
Sbjct: 1328 ANKEK-QELQEKLQALQSQVE----FLEQSMVD---KSLVSRQEAKIRELETRLEFERTQ 1379
Query: 588 IK 589
+K
Sbjct: 1380 VK 1381
Score = 47.2 bits (107), Expect = 2e-04
Identities = 60/281 (21%), Positives = 118/281 (41%), Gaps = 26/281 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKT 345
+ +D K++A SK A L+ N L+ +E KA + M E+E+ + DD K
Sbjct: 1212 LMLDHLKNSAPSKREIAQLK--NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1269
Query: 346 SHFESELYKTLDLAHDYQDKCKQ-------LQNEKKSLEEQLNTELDNVN---VMLSNKD 395
+ E +L + ++ Q++ ++ L + K+ Q + +L +N L +
Sbjct: 1270 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1329
Query: 396 KEIDVLKENYDTVMR----LNKQLTD--CVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
KE L+E + L + + D V E + + + + ++ + L
Sbjct: 1330 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1389
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + LT+ERD + N E+ + +++QL + + + E+ +K + E +
Sbjct: 1390 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARK----EAEASRKKHE 1445
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
LE+ L+ Q D LA + + E EME+D
Sbjct: 1446 LEMDLESLEAANQSLQADLKLA-FKRIGDLQAAIEDEMESD 1485
Score = 40.3 bits (90), Expect = 0.021
Identities = 47/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN---QCSEV 492
++ I ++ IQ + + +ER+ L+ + SR + + +L +++N S++
Sbjct: 794 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 853
Query: 493 L--KKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
L + + L + E+K L+ + K +++ + ++ +A L + E ++D + +
Sbjct: 854 LDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARLIRAAEINGEVD--DDDAG 910
Query: 549 NDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ RLK V F K+ L+ E + KLE+ ++Q E +L LQ + L +
Sbjct: 911 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER-RLGDLQADSEESQRALQQ 969
Query: 607 SKVECQRRRRGETAARLHAALQAHWRHAL 635
K +CQR +LH Q H L
Sbjct: 970 LKKKCQRLTAELQDTKLHLEGQQVRNHEL 998
Score = 40.3 bits (90), Expect = 0.021
Identities = 52/243 (21%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN---KDKEIDVLKENYDTVMRLNK 413
DL D ++ + LQ KK + +L EL + + L ++ E++ + +D+ +
Sbjct: 955 DLQADSEESQRALQQLKKKCQ-RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1013
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
+ K E L++EK D + L ++++ + + TQ+ L++++ +
Sbjct: 1014 EEAQREKLQREKLQREK---DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD--- 1067
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
I Q + + ++V K+ L+ +VK + L+ Q ++ LE A L
Sbjct: 1068 ----ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ-----MLEQAKLRLE 1118
Query: 534 QEFQEQLDRAEREMEN-DARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E + +EME+ D ++E + + +++EE+++ + VL EK+ E KL
Sbjct: 1119 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1178
Query: 591 YRL 593
L
Sbjct: 1179 ATL 1181
Score = 39.9 bits (89), Expect = 0.028
Identities = 74/331 (22%), Positives = 142/331 (42%), Gaps = 20/331 (6%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R L + R L+ +E +V + +KK F+SEL + + A + + +
Sbjct: 965 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1024
Query: 368 QLQNEKKSLEEQ---LNTELDNVNVMLSN-KDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+LQ EK L + L +L+ ++ ++ K + + E D + +K K +
Sbjct: 1025 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1084
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE-RSRCAVIEQ-- 480
+ + E D + + E IQ + L L E + ++ ++E SR +E+
Sbjct: 1085 QLRDLEAKVKDQ-EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1143
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
Q C+K+ + EV + ++ D + K LR+ EL+ Q D K ++ L
Sbjct: 1144 QSCQKKLKQMEVQLEEEYEDKQ-KVLREKRELEGKLATLSDQVNRRDFESEK--RLRKDL 1200
Query: 541 DRAEREMENDARLKENNIVDS--FNKQILRIEEQ-HKLEIN----VLEEKQRE-EIKLYR 592
R + + DA+L +++ +S ++I +++ Q + E V K E EI+
Sbjct: 1201 KRT-KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1259
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARL 623
LQ+ A+ LE ++ +R + E RL
Sbjct: 1260 LQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1290
Score = 32.7 bits (71), Expect = 4.2
Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 12/229 (5%)
Query: 377 EEQLNT---ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
EEQ+ E+ + L +KE + L+ N D + +LT + + E
Sbjct: 795 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 854
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER-SRCAVIEQQLCEKQNQCSEV 492
D+ + K ++ + + L ++ ++++ +V E R R A I ++ + + E
Sbjct: 855 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEV-DDDDAGGEW 913
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
K + EV ++ L+ Q+ E K ++Q + + +L + Q + ++R ++ +
Sbjct: 914 RLKYERAVREVDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQ-QLK 971
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
K + L +E Q ++ + LE+KQR + +L+QA E+
Sbjct: 972 KKCQRLTAELQDTKLHLEGQ-QVRNHELEKKQRR----FDSELSQAHEE 1015
>AK097432-1|BAC05050.1| 466|Homo sapiens protein ( Homo sapiens
cDNA FLJ40113 fis, clone TESTI2008621. ).
Length = 466
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/267 (26%), Positives = 132/267 (49%), Gaps = 32/267 (11%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLS--NKDKEIDVLKENYDTVMRLNKQLTDCVK 420
QD+ L+ E +S+ QL E++N N MLS N+ +E + L+E + RL +Q + ++
Sbjct: 163 QDETNHLRKELESVGRQLQAEVEN-NQMLSLLNRRQE-ERLREQEE---RLREQ-EERLR 216
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
EE L +++ + + E +R++ ++E L +ER + E R E+
Sbjct: 217 EQEERLHEQEERLCEQEERLCEQEERLRE-HEERLCEQEER------LREHEERLCEQEE 269
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
+LCE++ + E ++ + E + Q L + E + Q++ +L+E +E+L
Sbjct: 270 RLCEQEERLREQEER--LCEQEERLCEQEERLCEQEERLREQEERLCEQEERLREQEERL 327
Query: 541 -DRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--------EI-NVLEEKQREEIK- 589
++ ER E + RL E + +Q R+ EQ KL E+ +LE+++R+E +
Sbjct: 328 CEQEERLREQEERLCEQE--ERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQE 385
Query: 590 --LYRLQLAQAAEKLGLLESKVECQRR 614
L R +L + EKL E + E Q R
Sbjct: 386 RLLERERLLEEVEKLLEQERRQEEQER 412
Score = 52.8 bits (121), Expect = 4e-06
Identities = 72/322 (22%), Positives = 140/322 (43%), Gaps = 18/322 (5%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS-HFESE 351
RA + L + L +LD + A+ + E N V +KK H +
Sbjct: 78 RASSTTLEDLESQYQELAVALDSSS-----AIISQLTENINSLVRTSKEEKKHEIHLVQK 132
Query: 352 LYKTL-DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
L ++L L + + S EQL E +++ L + +++ EN +
Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL--KSKV 468
LN++ + ++ EE L +++ + + E +R+ E L QE L + ++
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLHEQEERL--CEQEERLCEQEERLREHEERL 250
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLED 527
E+ R E++LCE++ + E ++ + E + Q L ++ E C +++L +
Sbjct: 251 CEQEERLREHEERLCEQEERLCEQEER--LREQEERLCEQEERLCEQEERLCEQEERLRE 308
Query: 528 AVLAKLQEFQEQL-DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVL--EEKQ 584
+L E +E+L ++ ER E + RL+E ++ LR +E+ E L +E+
Sbjct: 309 QE-ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERL 367
Query: 585 REEIKLYRLQLAQAAEKLGLLE 606
EE++ Q + E+ LLE
Sbjct: 368 LEEVEKLLEQERRQEEQERLLE 389
Score = 42.3 bits (95), Expect = 0.005
Identities = 52/265 (19%), Positives = 119/265 (44%), Gaps = 13/265 (4%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E E + L L + Q++ + Q E+ + EE+L + + ++ ++ + L E +
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEER 242
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS- 466
+ ++L + + L E +E+ + + E +R++ E L QE L +
Sbjct: 243 LREHEERLCEQEERLRE--HEERLCEQEER--LCEQEERLRE--QEERLCEQEERLCEQE 296
Query: 467 -KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
++ E+ R E++LCE++ + E ++ + ++ + L Q+ L+ ++
Sbjct: 297 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLC 356
Query: 526 EDAVLAK----LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
E L L+E ++ L++ R+ E + L+ +++ K + + Q + E +
Sbjct: 357 EQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQEEQERLLER 416
Query: 582 EKQREEIKLYRLQLAQAAEKLGLLE 606
E+ EE++ Q + E+ LLE
Sbjct: 417 ERLLEEVEKLLEQERRQEEQERLLE 441
Score = 40.3 bits (90), Expect = 0.021
Identities = 56/264 (21%), Positives = 127/264 (48%), Gaps = 23/264 (8%)
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVK 420
+ +++ ++ + + EE+L+ + + + ++ + L+E+ + + ++L + +
Sbjct: 203 EQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLREHEERLCEQEERLREHEE 262
Query: 421 NL---EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS--KVNEERSRC 475
L EE L +++ + + E +R+ E L QE L + ++ E+ R
Sbjct: 263 RLCEQEERLCEQEERLREQEERLCEQEERL--CEQEERLCEQEERLREQEERLCEQEERL 320
Query: 476 AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQE 535
E++LCE++ + E ++ L + + LR+ E + K Q++L + V KL E
Sbjct: 321 REQEERLCEQEERLREQEER---LCEQEERLREQEERLCEQEKLPGQERLLEEV-EKLLE 376
Query: 536 FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--------EIN-VLEEKQRE 586
+ + + ER +E + L+E V+ +Q R EEQ +L E+ +LE+++R+
Sbjct: 377 QERRQEEQERLLERERLLEE---VEKLLEQERRQEEQERLLERERLLEEVEKLLEQERRQ 433
Query: 587 EIKLYRLQLAQAAEKLGLLESKVE 610
E + L+ + +++ L +VE
Sbjct: 434 EEQERLLERERLLDEVEELLDEVE 457
Score = 34.3 bits (75), Expect = 1.4
Identities = 48/274 (17%), Positives = 119/274 (43%), Gaps = 18/274 (6%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKA--LEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
+LRE RL +R ++ + E+ +CE E + + ++ H E L + +
Sbjct: 200 RLREQEERLREQEERLREQEERLHEQEERLCEQEER--LCEQEERLREH-EERLCEQEER 256
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+++++ + + EE+L + + + ++ + L E + + ++L +
Sbjct: 257 LREHEERLCEQEERLCEQEERLREQEERLCEQEERLCEQEERLCEQEERLREQEERLCEQ 316
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVND-ETLLLTQERDLLKSKVNEERSRCAV 477
+ L E E+ + + L ++ + + + E L QE+ + ++ EE + +
Sbjct: 317 EERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEK--L 374
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
+EQ+ +Q + +L++ L+ K L Q ++ E ++ LE E +
Sbjct: 375 LEQE--RRQEEQERLLERERLLEEVEKLLEQERRQEEQERLLERERLLE--------EVE 424
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
+ L++ R+ E + L+ ++D + + +EE
Sbjct: 425 KLLEQERRQEEQERLLERERLLDEVEELLDEVEE 458
>AK097424-1|BAC05045.1| 535|Homo sapiens protein ( Homo sapiens
cDNA FLJ40105 fis, clone TESTI2006383. ).
Length = 535
Score = 54.0 bits (124), Expect = 2e-06
Identities = 56/239 (23%), Positives = 113/239 (47%), Gaps = 13/239 (5%)
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
+S+F S T DL D D C EK S E+ TEL+N + L+N D + + +EN
Sbjct: 213 SSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDS--LTNGDLKSKLKQEN 270
Query: 405 YDTVMR---LNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQE 460
V R L + + D E+ALE+E H + E ++ +N L +E
Sbjct: 271 TQLVHRVHELEEMVKDQETTAEQALEEEARRHREAYGKLEREKAIEVELLNARVQQLEEE 330
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF-LDNEVKTLRQHLE-LQKNELK 518
L++ V +S+ ++L E++ + S+ L+ L +E+ ++ ++ L++N L+
Sbjct: 331 NTELRTTVTRLKSQ----TEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLE 386
Query: 519 CHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLE 576
+++ ++ L++ E L + + R + ++ + FN + +E +H+++
Sbjct: 387 FQKEREATQELIEDLRKELEHLQMYKLDCGRPGRGRSASSGLGEFNARAREVELEHEVK 445
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 54.0 bits (124), Expect = 2e-06
Identities = 64/302 (21%), Positives = 139/302 (46%), Gaps = 25/302 (8%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE--EQLNT 382
++M E F+ + D+ K + + K + L + D Q+Q E + L E+
Sbjct: 853 KEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD 912
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L + L K KE+ E+ + + N +LT + LE+ + K D + + +
Sbjct: 913 QLIKTKIQLEAKIKEVTERAEDEEEI---NAELTAKKRKLEDECSELKKDIDDLELTLAK 969
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
+ K + ++ LT+E + ++E ++ ++ L E Q + L+ +++
Sbjct: 970 VEKEKHATENKVKNLTEEM----AGLDETIAKLTKEKKALQEAHQQTLDDLQA---EEDK 1022
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
V TL K ++K Q + L + ++ + L+RA+R++E D +L + +I+D
Sbjct: 1023 VNTLT------KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076
Query: 563 NKQILRIEEQHKLEINV------LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
N++ E+ K E + +E++Q I+L + ++ + ++ LE ++E +R R
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK-KIKELQARIEELEEEIEAERASR 1135
Query: 617 GE 618
+
Sbjct: 1136 AK 1137
Score = 52.8 bits (121), Expect = 4e-06
Identities = 63/290 (21%), Positives = 126/290 (43%), Gaps = 14/290 (4%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT 382
+E++ E+E R A+K+ S EL + + + Q++ KK E
Sbjct: 1121 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK----FAHDSTKS 438
D L ++ + K++ D+V L +Q+ D ++ +++ LEKEK D S
Sbjct: 1181 RRDLEEATLQHEATAATLRKKHADSVAELGEQI-DNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 439 NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDF 498
N+ ++K ++ L + LKSK E++ + Q Q + E ++ D
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDE 1299
Query: 499 LDNEVKTL---RQHLELQKNELKCHYQKQL--EDAVLAKLQEFQEQLD--RAEREMENDA 551
+ V L +Q Q ELK ++++ ++A+ LQ + D R + E E ++
Sbjct: 1300 KEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQES 1359
Query: 552 RLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+ + + N ++ + +++ + + ++ EE K Q QAAE+
Sbjct: 1360 KAELQRALSKANTEVAQWRTKYETDA-IQRTEELEEAKKKLAQRLQAAEE 1408
Score = 44.8 bits (101), Expect = 0.001
Identities = 62/308 (20%), Positives = 131/308 (42%), Gaps = 32/308 (10%)
Query: 310 TNSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDK 365
TN+ A D+ ++ +K++ E E + +QK+ +EL+K + + D+
Sbjct: 1441 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQ 1500
Query: 366 CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA 425
+ L+ E K+L++ E+ ++ ++ K I L+ ++ KQ+ L+ A
Sbjct: 1501 LETLKRENKNLQQ----EISDLTEQIAEGGKRIHELE-------KIKKQVEQEKCELQAA 1549
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-----LLKSKVNEERSRCAVIEQ 480
LE+ + + + + I + + V E E+D L ++ + S + ++
Sbjct: 1550 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDA 1609
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
++ +N + KK + NE++ H E +Y+ L++ Q L
Sbjct: 1610 EI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN-----TQGILKDTQIHL 1663
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
D A R E+ LKE + +L+ E + E+ E+ K+ +L A+E
Sbjct: 1664 DDALRSQED---LKEQLAMVERRANLLQAEIE---ELRATLEQTERSRKIAEQELLDASE 1717
Query: 601 KLGLLESK 608
++ LL ++
Sbjct: 1718 RVQLLHTQ 1725
Score = 41.5 bits (93), Expect = 0.009
Identities = 41/192 (21%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 392 SNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNK---RIQ 448
S EID L N +TV + L + LE+ L + K + + I +L R+Q
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 449 SVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
+ + E E++ L S+++ + QQ+ E + Q E +K + L + +++ R
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQ---AFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK--QI 566
+L + + + + + E + L + ++ + + E DA + + ++ K Q
Sbjct: 1345 DCDLLREQYEEEQESKAE--LQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1402
Query: 567 LRIEEQHKLEIN 578
L+ E+H +N
Sbjct: 1403 LQAAEEHVEAVN 1414
Score = 40.3 bits (90), Expect = 0.021
Identities = 60/259 (23%), Positives = 103/259 (39%), Gaps = 27/259 (10%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E E+ LAH Q ++ EE+ ++ + + LS + E+ + Y+T
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAE-LQRALSKANTEVAQWRTKYET- 1383
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+ LEEA +K + + ++ +N + S+ L E + L V
Sbjct: 1384 -----DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1438
Query: 469 NEERSRCAVIEQQ-------LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ CA ++++ L E + +C E + + E ++L L KN +
Sbjct: 1439 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYE-ES 1497
Query: 522 QKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN-VL 580
QLE QE D E+ E R+ E ++ KQ+ EQ K E+ L
Sbjct: 1498 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE---LEKIKKQV----EQEKCELQAAL 1550
Query: 581 EEK----QREEIKLYRLQL 595
EE + EE K+ R+QL
Sbjct: 1551 EEAEASLEHEEGKILRIQL 1569
Score = 38.7 bits (86), Expect = 0.065
Identities = 53/301 (17%), Positives = 124/301 (41%), Gaps = 23/301 (7%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++ L+ + E + + +++ E L + L
Sbjct: 991 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Query: 359 AHDYQDKCKQLQNEKKSLEEQL---NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E + E ++ L K+ EI L+ + L QL
Sbjct: 1051 RMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQL 1110
Query: 416 TDCVKNL-------EEALEKEKFAHDSTKSNITELNKRIQSVNDETL----LLTQERDLL 464
+K L EE +E E+ + + ++L++ ++ +++ + + ++
Sbjct: 1111 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1170
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQ 524
K + E + +E+ + + + + KK D+ + Q LQ+ + K +K
Sbjct: 1171 KKREAEFQKMRRDLEEATLQHEATAATLRKK--HADSVAELGEQIDNLQRVKQKLEKEKS 1228
Query: 525 LEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
+ L E + +A+ +E R E+ + + +K+ EEQ +L ++ ++
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKE----EEQQRLINDLTAQRG 1284
Query: 585 R 585
R
Sbjct: 1285 R 1285
>AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.
Length = 1978
Score = 54.0 bits (124), Expect = 2e-06
Identities = 72/297 (24%), Positives = 134/297 (45%), Gaps = 36/297 (12%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
+ L+ A+ Y+ ++L N + L E +++ + KD EI LK+N + + +K
Sbjct: 731 RLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHK 790
Query: 414 QLTDCV-------KNLEEALEKEKFAHDSTKSNIT----ELNKRIQSVNDETLL--LTQE 460
+ D + K L + + K++ + K + EL+K Q++ +L +E
Sbjct: 791 ETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEE 850
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV-----LKKCDFLDNEVKTLRQHLELQKN 515
+D + EE + ++L E+Q++ + V L L +EV L E +
Sbjct: 851 KDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEE 910
Query: 516 ELKCHYQKQLED------AVLAKLQEFQEQLD--RAEREMENDAR----LKENNIVDSFN 563
E+K H+QK +ED +L LQE ++++D R + E N L+++ + S
Sbjct: 911 EIK-HHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQ 969
Query: 564 KQILRIEEQ---HKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K I +I+ Q + +I +E K+ L + +EK L SK E +R +G
Sbjct: 970 KTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDL--SKAETERLVKG 1024
Score = 46.8 bits (106), Expect = 2e-04
Identities = 66/286 (23%), Positives = 137/286 (47%), Gaps = 38/286 (13%)
Query: 360 HDYQD-KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
H+ D + KQL+ EK+ + ++L E D +++ K ++ EN+ + N+ L
Sbjct: 1388 HEQTDSEIKQLK-EKQDVLQKLLKEKD---LLIKAKSDQLLSSNENFTNKVNENELLRQA 1443
Query: 419 VKNLEEAL------------EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKS 466
V NL+E + E EK ++ + TE + +Q N + ++ +E++
Sbjct: 1444 VTNLKERILILEMDIGKLKGENEKIV-ETYRGKETEY-QALQETNMKFSMMLREKEF--- 1498
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE----LKCHYQ 522
+ + + + EQ L EK+ + L + L N VK++++ + + E + Q
Sbjct: 1499 ECHSMKEKALAFEQLLKEKEQGKTGELNQ---LLNAVKSMQEKTVVFQQERDQVMLALKQ 1555
Query: 523 KQLEDAVLA-KLQEFQEQLDRAEREMENDARLKENNI--VDSFNKQILRIEEQH---KLE 576
KQ+E+ L ++Q +++ R+ +E+E RL+ + + DS+ ++ L E++ + +
Sbjct: 1556 KQMENTALQNEVQRLRDKEFRSNQELE---RLRNHLLESEDSYTREALAAEDREAKLRKK 1612
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAAR 622
+ VLEEK QA+ ++ L+ ++ ++R ETA R
Sbjct: 1613 VTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALR 1658
Score = 46.4 bits (105), Expect = 3e-04
Identities = 57/294 (19%), Positives = 131/294 (44%), Gaps = 17/294 (5%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNE-KKSLEEQLNTE 383
+K+ +VEN + +Q+ + E + + +++ +++NE +SL + N+
Sbjct: 579 QKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSN 638
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITEL 443
+ +L ++ E+ LK+N + +LN+ L +++ EK A + + + E
Sbjct: 639 FKDT--LLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEEC 696
Query: 444 NKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+ N +L + LK + E + +++L E+ N+ + +++ N +
Sbjct: 697 ---LAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARN-L 752
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
T LE ++ +K + +K +E A L K E + + +++ + + ++ + N
Sbjct: 753 NTSALQLE-HEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLIN 811
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRG 617
K+ + IE ++ K +EE+ Y +QA K +L +E + R G
Sbjct: 812 KKEIFIE-----KLKERSSKLQEELDKY----SQALRKNEILRQTIEEKDRSLG 856
Score = 41.9 bits (94), Expect = 0.007
Identities = 68/282 (24%), Positives = 124/282 (43%), Gaps = 23/282 (8%)
Query: 319 RHRKAL---EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD-KCKQLQNEKK 374
RHR+ L E+ I E+EN Q + E++L K ++ Q + +++++ KK
Sbjct: 253 RHREELSDYEERIEELENLL-----QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKK 307
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
EQL ++ ++N LS+ + + D+L+ + + +Q+ + +NL+ LE K
Sbjct: 308 M--EQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLK--LECSKLQPS 363
Query: 435 STKSNITELNK-RIQSVNDETLLLTQERDLLKSKVNE-ERSRCAVIEQQLCE---KQNQC 489
+ K + T K RI + + + + R L NE R + L E K
Sbjct: 364 AVKQSDTMTEKERILAQSGSVEEVFRLRQALSDAENEIMRLSSLNQDNSLAEDNLKLKMR 423
Query: 490 SEVL-KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLDRAEREM 547
EVL K+ L E + L+ L NE + D L ++L + + L+ E+E+
Sbjct: 424 IEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 483
Query: 548 ENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREE 587
KE I ++ ++Q + +H + I KQ+ E
Sbjct: 484 NQSISEKETLIAEIEELDRQ-NQEATKHMILIKAQLSKQQNE 524
Score = 41.9 bits (94), Expect = 0.007
Identities = 67/303 (22%), Positives = 140/303 (46%), Gaps = 34/303 (11%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
SKL+ + ++ ++++ E A + EV R DA+ + S L + LA
Sbjct: 358 SKLQPSAVKQSDTM--TEKERILAQSGSVEEVFRLRQALSDAENEIMRLSS-LNQDNSLA 414
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
D +++ +K + L+ E + + + L + E +V+K + L+ +L D
Sbjct: 415 EDNLKLKMRIEVLEKE-KSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLR 473
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR-CAVI 478
NLE KE+ ELN QS++++ L+ + +L + N+E ++ +I
Sbjct: 474 LNLE---AKEQ-----------ELN---QSISEKETLIAEIEEL--DRQNQEATKHMILI 514
Query: 479 EQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
+ QL ++QN+ ++ K L++E K + Q L+ +++ + ++ +L + +
Sbjct: 515 KAQLSKQQNEGDSIISKLKQDLNDEKKRVHQ---LEDDKMDITKELDVQFVLLIQSEVAL 571
Query: 538 EQLDRAEREMENDARLKENNIVDSFNK-QILRIE-EQHKLEINVLEEKQREEIKLYRLQL 595
L ++++E+ K N+VD NK Q + ++ LE+ + EE+ R +L
Sbjct: 572 NDLHLTKQKLED----KVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNEL 627
Query: 596 AQA 598
Q+
Sbjct: 628 MQS 630
Score = 40.7 bits (91), Expect = 0.016
Identities = 45/236 (19%), Positives = 97/236 (41%), Gaps = 17/236 (7%)
Query: 321 RKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSL---- 376
++ L+ E E V ++ ++ SH ++E +K +D+ + +LQ+E K L
Sbjct: 1088 QQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRF 1147
Query: 377 ----EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF- 431
++ + N++ ++ KD EID L + T++ + + T N + +F
Sbjct: 1148 ESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQ--TSSTGNEAGGVNSNQFE 1205
Query: 432 ----AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
D K + ++ + Q V + E L+ ++++ +++ V + Q
Sbjct: 1206 ELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQV 1265
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
+ +++ + NE K EL + + +D +L KL QL A
Sbjct: 1266 DYTGLIQ--SYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSA 1319
Score = 39.1 bits (87), Expect = 0.049
Identities = 50/250 (20%), Positives = 110/250 (44%), Gaps = 19/250 (7%)
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKEN----YDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
E L EL+ + L KD I L+EN D++ ++ + + +++ K
Sbjct: 1343 ELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQ 1402
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQ-------ERDLLKSKVNEERSRCAVIEQQLCEKQ 486
D + + E + I++ +D+ L + E +LL+ V + R ++E + + +
Sbjct: 1403 DVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLK 1462
Query: 487 NQCSEVLKKCDFLDNEVKTLRQ-----HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
+ ++++ + E + L++ + L++ E +CH K+ A L+E ++
Sbjct: 1463 GENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKT 1522
Query: 542 RAEREMENDAR-LKENNIV-DSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRLQLAQA 598
++ N + ++E +V Q++ +Q ++E L+ E QR K +R
Sbjct: 1523 GELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELE 1582
Query: 599 AEKLGLLESK 608
+ LLES+
Sbjct: 1583 RLRNHLLESE 1592
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/302 (24%), Positives = 134/302 (44%), Gaps = 38/302 (12%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
I L +A LRL ++R H K +E EVE R QKK E + L
Sbjct: 1241 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR---QSCQKKLKQME------VQL 1291
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+Y+DK K L+ EK+ LE +L T D VN +K + + ++ + + D
Sbjct: 1292 EEEYEDKQKVLR-EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1350
Query: 419 VKN----------LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+KN L+ LE+ +F + + I+ ++ + + + + L+ ++
Sbjct: 1351 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1410
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLED 527
+ + I+ +L E Q +E++KK ++ + +L Q N+L Q QLE+
Sbjct: 1411 SRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLAQINDL----QAQLEE 1461
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
A K QE QE+L + ++E E ++VD K ++ +E E+ E +R +
Sbjct: 1462 ANKEK-QELQEKLQALQSQVE----FLEQSMVD---KSLVSRQEAKIRELETRLEFERTQ 1513
Query: 588 IK 589
+K
Sbjct: 1514 VK 1515
Score = 47.2 bits (107), Expect = 2e-04
Identities = 60/281 (21%), Positives = 118/281 (41%), Gaps = 26/281 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKT 345
+ +D K++A SK A L+ N L+ +E KA + M E+E+ + DD K
Sbjct: 1346 LMLDHLKNSAPSKREIAQLK--NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1403
Query: 346 SHFESELYKTLDLAHDYQDKCKQ-------LQNEKKSLEEQLNTELDNVN---VMLSNKD 395
+ E +L + ++ Q++ ++ L + K+ Q + +L +N L +
Sbjct: 1404 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1463
Query: 396 KEIDVLKENYDTVMR----LNKQLTD--CVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
KE L+E + L + + D V E + + + + ++ + L
Sbjct: 1464 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1523
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + LT+ERD + N E+ + +++QL + + + E+ +K + E +
Sbjct: 1524 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARK----EAEASRKKHE 1579
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
LE+ L+ Q D LA + + E EME+D
Sbjct: 1580 LEMDLESLEAANQSLQADLKLA-FKRIGDLQAAIEDEMESD 1619
Score = 40.3 bits (90), Expect = 0.021
Identities = 47/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN---QCSEV 492
++ I ++ IQ + + +ER+ L+ + SR + + +L +++N S++
Sbjct: 928 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 987
Query: 493 L--KKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
L + + L + E+K L+ + K +++ + ++ +A L + E ++D + +
Sbjct: 988 LDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARLIRAAEINGEVD--DDDAG 1044
Query: 549 NDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ RLK V F K+ L+ E + KLE+ ++Q E +L LQ + L +
Sbjct: 1045 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER-RLGDLQADSEESQRALQQ 1103
Query: 607 SKVECQRRRRGETAARLHAALQAHWRHAL 635
K +CQR +LH Q H L
Sbjct: 1104 LKKKCQRLTAELQDTKLHLEGQQVRNHEL 1132
Score = 40.3 bits (90), Expect = 0.021
Identities = 52/243 (21%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN---KDKEIDVLKENYDTVMRLNK 413
DL D ++ + LQ KK + +L EL + + L ++ E++ + +D+ +
Sbjct: 1089 DLQADSEESQRALQQLKKKCQ-RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1147
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
+ K E L++EK D + L ++++ + + TQ+ L++++ +
Sbjct: 1148 EEAQREKLQREKLQREK---DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD--- 1201
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
I Q + + ++V K+ L+ +VK + L+ Q ++ LE A L
Sbjct: 1202 ----ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ-----MLEQAKLRLE 1252
Query: 534 QEFQEQLDRAEREMEN-DARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E + +EME+ D ++E + + +++EE+++ + VL EK+ E KL
Sbjct: 1253 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1312
Query: 591 YRL 593
L
Sbjct: 1313 ATL 1315
Score = 39.9 bits (89), Expect = 0.028
Identities = 74/331 (22%), Positives = 142/331 (42%), Gaps = 20/331 (6%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R L + R L+ +E +V + +KK F+SEL + + A + + +
Sbjct: 1099 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1158
Query: 368 QLQNEKKSLEEQ---LNTELDNVNVMLSN-KDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+LQ EK L + L +L+ ++ ++ K + + E D + +K K +
Sbjct: 1159 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1218
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE-RSRCAVIEQ-- 480
+ + E D + + E IQ + L L E + ++ ++E SR +E+
Sbjct: 1219 QLRDLEAKVKDQ-EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1277
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
Q C+K+ + EV + ++ D + K LR+ EL+ Q D K ++ L
Sbjct: 1278 QSCQKKLKQMEVQLEEEYEDKQ-KVLREKRELEGKLATLSDQVNRRDFESEK--RLRKDL 1334
Query: 541 DRAEREMENDARLKENNIVDS--FNKQILRIEEQ-HKLEIN----VLEEKQRE-EIKLYR 592
R + + DA+L +++ +S ++I +++ Q + E V K E EI+
Sbjct: 1335 KRT-KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1393
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARL 623
LQ+ A+ LE ++ +R + E RL
Sbjct: 1394 LQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1424
Score = 32.7 bits (71), Expect = 4.2
Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 12/229 (5%)
Query: 377 EEQLNT---ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
EEQ+ E+ + L +KE + L+ N D + +LT + + E
Sbjct: 929 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 988
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER-SRCAVIEQQLCEKQNQCSEV 492
D+ + K ++ + + L ++ ++++ +V E R R A I ++ + + E
Sbjct: 989 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEV-DDDDAGGEW 1047
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
K + EV ++ L+ Q+ E K ++Q + + +L + Q + ++R ++ +
Sbjct: 1048 RLKYERAVREVDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQ-QLK 1105
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
K + L +E Q ++ + LE+KQR + +L+QA E+
Sbjct: 1106 KKCQRLTAELQDTKLHLEGQ-QVRNHELEKKQRR----FDSELSQAHEE 1149
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 54.0 bits (124), Expect = 2e-06
Identities = 75/302 (24%), Positives = 134/302 (44%), Gaps = 38/302 (12%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
I L +A LRL ++R H K +E EVE R QKK E + L
Sbjct: 1557 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR---QSCQKKLKQME------VQL 1607
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
+Y+DK K L+ EK+ LE +L T D VN +K + + ++ + + D
Sbjct: 1608 EEEYEDKQKVLR-EKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH 1666
Query: 419 VKN----------LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+KN L+ LE+ +F + + I+ ++ + + + + L+ ++
Sbjct: 1667 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1726
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLEL-QKNELKCHYQKQLED 527
+ + I+ +L E Q +E++KK ++ + +L Q N+L Q QLE+
Sbjct: 1727 SRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLAQINDL----QAQLEE 1777
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
A K QE QE+L + ++E E ++VD K ++ +E E+ E +R +
Sbjct: 1778 ANKEK-QELQEKLQALQSQVE----FLEQSMVD---KSLVSRQEAKIRELETRLEFERTQ 1829
Query: 588 IK 589
+K
Sbjct: 1830 VK 1831
Score = 50.0 bits (114), Expect = 3e-05
Identities = 64/308 (20%), Positives = 133/308 (43%), Gaps = 30/308 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKT 345
+ +D K++A SK A L+ N L+ +E KA + M E+E+ + DD K
Sbjct: 1662 LMLDHLKNSAPSKREIAQLK--NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1719
Query: 346 SHFESELYKTLDLAHDYQDKCKQ-------LQNEKKSLEEQLNTELDNVN---VMLSNKD 395
+ E +L + ++ Q++ ++ L + K+ Q + +L +N L +
Sbjct: 1720 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1779
Query: 396 KEIDVLKENYDTVMR----LNKQLTD--CVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
KE L+E + L + + D V E + + + + ++ + L
Sbjct: 1780 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASR 1839
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + LT+ERD + N E+ + +++QL + + + E+ +K + E +
Sbjct: 1840 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARK----EAEASRKKHE 1895
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
LE+ L+ Q D LA + + E EME+D + ++++S + +
Sbjct: 1896 LEMDLESLEAANQSLQADLKLA-FKRIGDLQAAIEDEMESD---ENEDLINSLQDMVTKY 1951
Query: 570 EE-QHKLE 576
++ ++KLE
Sbjct: 1952 QKRKNKLE 1959
Score = 40.3 bits (90), Expect = 0.021
Identities = 47/209 (22%), Positives = 95/209 (45%), Gaps = 13/209 (6%)
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN---QCSEV 492
++ I ++ IQ + + +ER+ L+ + SR + + +L +++N S++
Sbjct: 1244 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1303
Query: 493 L--KKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREME 548
L + + L + E+K L+ + K +++ + ++ +A L + E ++D + +
Sbjct: 1304 LDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARLIRAAEINGEVD--DDDAG 1360
Query: 549 NDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
+ RLK V F K+ L+ E + KLE+ ++Q E +L LQ + L +
Sbjct: 1361 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER-RLGDLQADSEESQRALQQ 1419
Query: 607 SKVECQRRRRGETAARLHAALQAHWRHAL 635
K +CQR +LH Q H L
Sbjct: 1420 LKKKCQRLTAELQDTKLHLEGQQVRNHEL 1448
Score = 40.3 bits (90), Expect = 0.021
Identities = 52/243 (21%), Positives = 109/243 (44%), Gaps = 22/243 (9%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN---KDKEIDVLKENYDTVMRLNK 413
DL D ++ + LQ KK + +L EL + + L ++ E++ + +D+ +
Sbjct: 1405 DLQADSEESQRALQQLKKKCQ-RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1463
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
+ K E L++EK D + L ++++ + + TQ+ L++++ +
Sbjct: 1464 EEAQREKLQREKLQREK---DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQD--- 1517
Query: 474 RCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKL 533
I Q + + ++V K+ L+ +VK + L+ Q ++ LE A L
Sbjct: 1518 ----ISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQ-----MLEQAKLRLE 1568
Query: 534 QEFQEQLDRAEREMEN-DARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E + +EME+ D ++E + + +++EE+++ + VL EK+ E KL
Sbjct: 1569 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1628
Query: 591 YRL 593
L
Sbjct: 1629 ATL 1631
Score = 39.9 bits (89), Expect = 0.028
Identities = 74/331 (22%), Positives = 142/331 (42%), Gaps = 20/331 (6%)
Query: 308 RLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
R L + R L+ +E +V + +KK F+SEL + + A + + +
Sbjct: 1415 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1474
Query: 368 QLQNEKKSLEEQ---LNTELDNVNVMLSN-KDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+LQ EK L + L +L+ ++ ++ K + + E D + +K K +
Sbjct: 1475 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1534
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE-RSRCAVIEQ-- 480
+ + E D + + E IQ + L L E + ++ ++E SR +E+
Sbjct: 1535 QLRDLEAKVKDQ-EEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1593
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
Q C+K+ + EV + ++ D + K LR+ EL+ Q D K ++ L
Sbjct: 1594 QSCQKKLKQMEVQLEEEYEDKQ-KVLREKRELEGKLATLSDQVNRRDFESEK--RLRKDL 1650
Query: 541 DRAEREMENDARLKENNIVDS--FNKQILRIEEQ-HKLEIN----VLEEKQRE-EIKLYR 592
R + + DA+L +++ +S ++I +++ Q + E V K E EI+
Sbjct: 1651 KRT-KALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1709
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARL 623
LQ+ A+ LE ++ +R + E RL
Sbjct: 1710 LQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1740
Score = 32.7 bits (71), Expect = 4.2
Identities = 47/229 (20%), Positives = 101/229 (44%), Gaps = 12/229 (5%)
Query: 377 EEQLNT---ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
EEQ+ E+ + L +KE + L+ N D + +LT + + E
Sbjct: 1245 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1304
Query: 434 DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER-SRCAVIEQQLCEKQNQCSEV 492
D+ + K ++ + + L ++ ++++ +V E R R A I ++ + + E
Sbjct: 1305 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEV-DDDDAGGEW 1363
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
K + EV ++ L+ Q+ E K ++Q + + +L + Q + ++R ++ +
Sbjct: 1364 RLKYERAVREVDFTKKRLQ-QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQ-QLK 1421
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
K + L +E Q ++ + LE+KQR + +L+QA E+
Sbjct: 1422 KKCQRLTAELQDTKLHLEGQ-QVRNHELEKKQRR----FDSELSQAHEE 1465
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain
(1437 AA) protein.
Length = 1437
Score = 53.6 bits (123), Expect = 2e-06
Identities = 58/293 (19%), Positives = 130/293 (44%), Gaps = 20/293 (6%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K++ E E+ + +D+ + + ++K LEE++ T L N + E D L +
Sbjct: 343 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 402
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+ +L K ++E E+ + + + +T ++++ E + +L
Sbjct: 403 AEERCEQLIKNKIQLEAKIKEVTERAE-EEEEINAELTAKKRKLEDECSELKKDIDDLEL 461
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE----- 516
+KV +E+ + L E+ E + K ++ Q +LQ E
Sbjct: 462 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 521
Query: 517 ---LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
K ++Q++D L + ++ + L+RA+R++E D +L + + +D+ N + E+
Sbjct: 522 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEK 581
Query: 572 QHKLE------INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
K E I+ +E++Q EI+L + ++ + ++ L ++E +R R +
Sbjct: 582 LEKKEFEISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASRAK 633
Score = 48.0 bits (109), Expect = 1e-04
Identities = 62/301 (20%), Positives = 128/301 (42%), Gaps = 26/301 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK++ +EL+K ++ + D+ + L+
Sbjct: 944 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1003
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L++ E+ ++ ++ K+I L+ ++ KQ+ ++ ALE+ +
Sbjct: 1004 ENKNLQQ----EISDLTEQIAEGGKQIHELE-------KIKKQVEQEKCEIQAALEEAEA 1052
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE----KQN 487
+ + + I + + V E E+D ++ +R Q + +N
Sbjct: 1053 SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRN 1112
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
V KK + NE++ H E +Y+ L+E Q LD A R
Sbjct: 1113 DALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRN-----TQGILKETQLHLDDALRGQ 1167
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
E+ LKE + +L+ E + LE+ +R K+ +L A+E++ LL +
Sbjct: 1168 ED---LKEQLAIVERRANLLQAEIEELWA--TLEQTERSR-KIAEQELLDASERVQLLHT 1221
Query: 608 K 608
+
Sbjct: 1222 Q 1222
Score = 43.6 bits (98), Expect = 0.002
Identities = 52/287 (18%), Positives = 128/287 (44%), Gaps = 21/287 (7%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNV 389
++++ + +K+ E+++ + + +L EKK+L+E LD+
Sbjct: 455 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD--- 511
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
L ++ ++++L + +L +Q+ D LE +LE+EK + +L ++
Sbjct: 512 -LQAEEDKVNILTK---AKTKLEQQVDD----LEGSLEQEKKLRMDLERAKRKLEGDLKL 563
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ T+ ++ L K+ ++ + + ++ ++Q ++ KK L ++ L +
Sbjct: 564 AQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE 623
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+E ++ + +KQ D + +L+E E+L+ A L + + F K +
Sbjct: 624 IEAERAS-RAKAEKQRSD-LSRELEEISERLEEAGGATSAQVELNKKREAE-FQKLRRDL 680
Query: 570 EE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR 613
EE QH+ + L +K + + +L + + L ++ K+E ++
Sbjct: 681 EEATLQHEAMVAALRKKHADSM----AELGEQIDNLQRVKQKLEKEK 723
Score = 35.5 bits (78), Expect = 0.60
Identities = 54/271 (19%), Positives = 113/271 (41%), Gaps = 26/271 (9%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
L+ Q +Q++ K LEE+ + + + S++ + D+L+E Y+ +L
Sbjct: 804 LSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH-DCDLLREQYEEEQEGKAEL-- 860
Query: 418 CVKNLEEALEKEKFAHDSTKSNI-TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
+ AL K ++N T+ +R + + + L Q + V ++CA
Sbjct: 861 -----QRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA 915
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
+E+ KQ L NEV+ L L+++++ C + + L E+
Sbjct: 916 SLEK---TKQR-----------LQNEVEDLM--LDVERSNAACAALDKKQRNFDKVLSEW 959
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ-REEIKLYRLQL 595
+++ + + E+E + + + F + + E +LE E K ++EI Q+
Sbjct: 960 KQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQI 1019
Query: 596 AQAAEKLGLLESKVECQRRRRGETAARLHAA 626
A+ +++ LE + + + E A L A
Sbjct: 1020 AEGGKQIHELEKIKKQVEQEKCEIQAALEEA 1050
Score = 34.7 bits (76), Expect = 1.1
Identities = 57/276 (20%), Positives = 115/276 (41%), Gaps = 30/276 (10%)
Query: 291 VDRAKDAAISKLREAWLRLTN---SLDRAEDRHRKALEKM-ICEVENFRVV--ADDAQKK 344
V+R + +++ E W L S AE A E++ + +N ++ +
Sbjct: 1177 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1236
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
S +SE+ + + + + ++K K+ + + E+L E D + L
Sbjct: 1237 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQD-TSAHLE------------ 1283
Query: 405 YDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
R+ K L VK+L+ L E E+ A K I +L R++ + E + Q+R+
Sbjct: 1284 -----RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGE-VENEQKRNA 1337
Query: 464 LKSK-VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ 522
K + + R + Q E + + D L +VK+ ++ E + + +
Sbjct: 1338 EAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLS 1397
Query: 523 KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
K + + +L+E +E+ D AE ++ N R+K +
Sbjct: 1398 KFRK--LQHELEEAEERADIAESQV-NKLRVKSREV 1430
Score = 34.3 bits (75), Expect = 1.4
Identities = 58/342 (16%), Positives = 149/342 (43%), Gaps = 20/342 (5%)
Query: 302 LREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
L+E + + L ED+ KA K+ +V++ + +K E K
Sbjct: 501 LQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 560
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
Q+ +N+K+ L+E+L + ++ ++S + E V + + L ++ +
Sbjct: 561 LKLAQESTMDNENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL 620
Query: 419 VKNLE----EALEKEKFAHDSTKSNITELNKRIQSVNDET---LLLTQERDLLKSKVNEE 471
+ +E + EK D ++ + E+++R++ T + L ++R+ K+ +
Sbjct: 621 GEEIEAERASRAKAEKQRSDLSR-ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRD 679
Query: 472 RSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA- 528
+ + + ++ + + + +DN ++ ++Q LE +K+ELK +A
Sbjct: 680 LEEATLQHEAMVAALRKKHADSMAELGEQIDN-LQRVKQKLEKEKSELKMETDDLSSNAE 738
Query: 529 VLAKLQ-EFQEQLDRAEREMENDARLKE---NNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
++K + ++ R+ + ++ + KE +++ Q R++ + L+EK
Sbjct: 739 AISKAKGNLEKDGGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKD 798
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+L R + A + +++ L+ ++E + + + A L ++
Sbjct: 799 ALVSQLSRSKQA-STQQIEELKHQLEEETKAKNALAHALQSS 839
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/303 (18%), Positives = 137/303 (45%), Gaps = 20/303 (6%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++++ D ++ ++E + L+ + K+ E+++ E R + + + + FE
Sbjct: 1162 QIEKLSDKVVASVKEG---VQGPLNVSLSEEGKSQEQIL---EILRFIRREKEIAETRFE 1215
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK--ENYDT 407
++L Y+ + + L+ E + L++ LN E + V V + +++K E +
Sbjct: 1216 VAQVESLR----YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNV 1271
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
VM NK L + + LE+ L++ + + +I L + +++++ +L E+ LL+
Sbjct: 1272 VMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Query: 468 VNEERSRCA-VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
V ++R ++ QQ + ++L + + ++ L + + K E+
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-----QILRIEEQHKLEINVLE 581
+ L +Q +E L++ E E + + I+D K Q+ +I ++K + L+
Sbjct: 1392 NQNL--IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK 1449
Query: 582 EKQ 584
+Q
Sbjct: 1450 AQQ 1452
Score = 48.4 bits (110), Expect = 8e-05
Identities = 67/333 (20%), Positives = 144/333 (43%), Gaps = 34/333 (10%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV----VADDAQKKTSHFESELYKT 355
++L + + + +D R+A+E M ++ + V ++ Q+ + L
Sbjct: 1002 TQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLN 412
D Q++ K + E +L +V + + K+ K V + +T +
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAE 1121
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV--NE 470
QL +C + EE +E+ D + R + + + LL + + L KV +
Sbjct: 1122 SQLLECKASWEE---RERMLKDEVSKCVC----RCEDLEKQNRLLHDQIEKLSDKVVASV 1174
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+ + L E+ ++L+ F+ E + E+ + E Y++++E +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVE-SLRYRQRVE-LLE 1232
Query: 531 AKLQEFQEQLDRAEREM---------ENDARLKEN---NIVDSFNKQILRIEEQHKLEIN 578
+LQE Q+ L+ AERE +++ +K+ N+V NK + +E+ + ++
Sbjct: 1233 RELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 579 VLEEKQRE-EIKLYRLQLAQA--AEKLGLLESK 608
++ K R+ E+ + LQ A A +EK G+L+++
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Score = 44.8 bits (101), Expect = 0.001
Identities = 70/377 (18%), Positives = 154/377 (40%), Gaps = 40/377 (10%)
Query: 218 QNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXX 277
Q + I+T+ DL +E R + + +++KL E RL ++ E+++
Sbjct: 756 QEQIINTMTQDLRGANEKLAVAEIRAENLKK--EKEMLKLSEVRLSQQR-ESLLAEQRGQ 812
Query: 278 XXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ ++R++ +L +L + + + + +E+ N V
Sbjct: 813 NLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQ 872
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE-------------- 383
D +++ + T +L + Q + L+ ++E Q+ ++
Sbjct: 873 LLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKE 932
Query: 384 -LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-- 440
+D++ L +++++ LKE T +Q V +LEE+L KEK + + NI
Sbjct: 933 DVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Query: 441 ---------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
T+L K++ V E L ++ + + + + +++ L QN+ E
Sbjct: 993 RLKESAEFQTQLEKKLMEVEKEKQELQDDK---RRAIESMEQQLSELKKTLSSVQNEVQE 1049
Query: 492 VLKKCD-FLDNEVKTLRQHLELQK--NELKCHYQKQ--LEDAVLAKLQEFQEQLDR---A 543
L++ L NE + R E K E + Y+++ L A + LQ +EQ+ +
Sbjct: 1050 ALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV 1109
Query: 544 EREMENDARLKENNIVD 560
+ +E + E+ +++
Sbjct: 1110 RQHLEETTQKAESQLLE 1126
Score = 41.1 bits (92), Expect = 0.012
Identities = 61/306 (19%), Positives = 124/306 (40%), Gaps = 19/306 (6%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT-ELDNVN 388
E E Q K E ++ + + +K LQ EKK LEE + + N +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 389 VMLSNKDKEID----VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
++ KD + + +L E R+ +QLT+ + L+ + + + + ++ I L
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTKRI-QQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD-FLDNEV 503
+ + V E + ++ D + E+ +++ + Q E+ + D ++
Sbjct: 1401 EDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSA 1460
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER---EMENDAR-LKENNIV 559
++ H E + + K+ + K + + Q++ ++ E E +AR L+E +
Sbjct: 1461 QSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 560 DSFNKQILRI--------EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
LR EEQ + +I EEK R+ I + ++A A L + E
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEE 1580
Query: 612 QRRRRG 617
++R G
Sbjct: 1581 LKQRNG 1586
Score = 39.9 bits (89), Expect = 0.028
Identities = 66/297 (22%), Positives = 130/297 (43%), Gaps = 37/297 (12%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
C +EN + +++ + ++ D K K+ + ++ S+EE+ + EL N +
Sbjct: 224 CNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 389 VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ LSN + K D + +LT V+ L + L++ A+ + + ++ E+ +
Sbjct: 283 IKLSN------LYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336
Query: 449 SVNDETL----LLTQERDLLKSKVNEERSRCAVI-EQQLCEKQNQCSEVLK------KCD 497
+ E L L +E + ++ + + A++ E++L + V K K
Sbjct: 337 QMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLT 396
Query: 498 FLDNEVKTLRQHLELQKNELK--CHYQKQLEDAVLAK---LQEFQEQLDRA--------- 543
L N + L L+K E K Y ++ V AK L+ +E+ +RA
Sbjct: 397 ELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSV 456
Query: 544 --EREMENDARLKENNIVDSFNKQILRIE-EQHKLEINVLEEKQREEIKLYRLQLAQ 597
E+ M+ RL+E+ D NKQ +E + ++EI V + Q+ + L L+ A+
Sbjct: 457 KLEQAMKEIQRLQED--TDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 511
Score = 39.5 bits (88), Expect = 0.037
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNI---TELNKRIQSVN 451
+E+ LKE + +K L V+NL++ L EKE A + + + +EL++ Q +
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
D T Q R + K EE++R A++ + K + V + + E+K L+
Sbjct: 1534 DRTTQEEQLRQQITEK--EEKTRKAIVAAK--SKIAHLAGVKDQLTKENEELKQRNGALD 1589
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQL-DRAEREME-NDARLKENNIVDSFNKQI 566
QK+EL L+ ++ + +L + ER +E D + +N V +QI
Sbjct: 1590 QQKDELDVRI-TALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQI 1645
Score = 35.1 bits (77), Expect = 0.80
Identities = 54/277 (19%), Positives = 120/277 (43%), Gaps = 26/277 (9%)
Query: 367 KQLQNEKKSLEEQLNTELDNVN-----VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
K +QN+ + +E+D + + ++ + ++ K + RL + +C ++
Sbjct: 19 KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETREC-QS 77
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
L LEK ++ K+ +TE NK ++ D + + + K ++ E+ ++
Sbjct: 78 LRLELEK---LNNQLKA-LTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER 133
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH--YQKQLEDAVLAKLQEFQEQ 539
L ++ +E +K+ + E T + L+L+ +EL+ K E +L++ +E
Sbjct: 134 LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE----KRLEQEKEL 189
Query: 540 LDRAEREMENDARLKENNIV---DSFNKQILRIE---EQHKLEINVLEEKQREEIKLYRL 593
L + + + K + ++ +IL ++ E K E++ LEE Q +K
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE-QMNGLKTSNE 248
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L + E L +K++ + ++ + H L AH
Sbjct: 249 HLQKHVED---LLTKLKEAKEQQASMEEKFHNELNAH 282
>D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein.
Length = 1593
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 24/269 (8%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN-VNVMLSNKDKEIDV 400
+++T + +E+ K L QD + Q L + E D ++ ++S ++E ++
Sbjct: 1096 EQETENLRTEISK---LNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNI 1152
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRI--QSVNDETLLL 457
LK + V L+ Q + KNL+E + + + DS S + + +++I Q E ++
Sbjct: 1153 LKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQ 1212
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC----DFLDNEVKTLRQHLELQ 513
E+D K ++E+ R +I++ CEK LK+ + ++ E+ +HLE Q
Sbjct: 1213 NLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQ 1272
Query: 514 -------------KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+ L Q++L++ L++ +EQ R EM+N
Sbjct: 1273 IAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT 1332
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
+FN + R + + + IN L +K + ++
Sbjct: 1333 NFNTVLTREKMRKENIINDLSDKLKSTMQ 1361
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/267 (23%), Positives = 118/267 (44%), Gaps = 26/267 (9%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEIDVLKENY 405
E + L L ++Y+ K L E + E ++L EL + +L NKD E ++K
Sbjct: 863 EKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEK 922
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
+ V+ L + ++ LE E H S I EL + + V ++ L E D
Sbjct: 923 EAVICLQNEKD------QKLLEMENIMH-SQNCEIKELKQSREIVLEDLKKLHVEND--- 972
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+ R+ +EQ ++ +V +F K + H + ELK Q+
Sbjct: 973 EKLQLLRAELQSLEQSHLKELEDTLQVRHIQEF----EKVMTDH-RVSLEELKKENQQ-- 1025
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-QI-LRIEEQHKLEINV-LEE 582
++ ++QE ++ + + + + +LK +++ D+ K ++ L ++E EI + LEE
Sbjct: 1026 ---IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEE 1082
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKV 609
+ ++ + + L Q E L SK+
Sbjct: 1083 SRAQQKETLKSLLEQETENLRTEISKL 1109
Score = 32.3 bits (70), Expect = 5.6
Identities = 38/195 (19%), Positives = 87/195 (44%), Gaps = 14/195 (7%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRH-RKALEKMICEVENFRVVADDAQKK 344
A+ +++ + +S + +L L+ +D + AL++ E E VV + +K
Sbjct: 1209 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLERE---VVEKELLEK 1265
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
H E+++ K+ + D + ++ L+E+ L+ + K++E+ +N
Sbjct: 1266 VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEM----QN 1321
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAH---DSTKSNITELNK---RIQSVNDETLLLT 458
T + +Q E + KE + D KS + + + I+S++++ L
Sbjct: 1322 VRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLL 1381
Query: 459 QERDLLKSKVNEERS 473
+E+ L+ +V++ RS
Sbjct: 1382 EEKKKLEEEVSKLRS 1396
>BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated
motility receptor (RHAMM) protein.
Length = 725
Score = 53.6 bits (123), Expect = 2e-06
Identities = 65/275 (23%), Positives = 120/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 148 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 207
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 208 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 267
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E+ + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 268 EILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFI 327
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 328 LEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMAKEKNLFEEELKQTLDELD 387
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 388 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 422
Score = 52.4 bits (120), Expect = 5e-06
Identities = 73/342 (21%), Positives = 147/342 (42%), Gaps = 24/342 (7%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N + Q++ + + + L ++ L + S +
Sbjct: 306 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 365
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN-------LEE------ 424
E++ E + L E+D L++ + RL KQL + K+ LEE
Sbjct: 366 EEMAKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKE 425
Query: 425 -ALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
LEK AH + E + +QS+ D T + L S++ + + + +++++
Sbjct: 426 AELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKV 485
Query: 483 CEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQ-KNELKCHYQKQLEDAVLAKLQEFQEQL 540
+ +V + + + + +R L+LQ K+ LK K++ + L K+ + Q QL
Sbjct: 486 AKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQL 545
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL-AQAA 599
+ E + +E + N EE +K + L E+ + K ++LQL A
Sbjct: 546 KQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRL--LYEELYNKTKPFQLQLDAFEV 603
Query: 600 EKLGLLESKVECQRR--RRGETAARL--HAALQAHWRHALRI 637
EK LL Q + + ++ A+L H L+ +H +++
Sbjct: 604 EKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKL 645
Score = 45.6 bits (103), Expect = 6e-04
Identities = 50/244 (20%), Positives = 114/244 (46%), Gaps = 15/244 (6%)
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
DK++ +L++ +++ +++LE LEK + ++ T L+ ++ +
Sbjct: 82 DKDLKILEKEICVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQL 141
Query: 455 LLLTQERDLLKSKVNE--ERSRCAVIEQQLCEKQN----QCSEVLKKCDFLDNEVKTLRQ 508
+ LT+ +LLKSK +E + ++ +L + +N + ++ K + ++ +++ ++
Sbjct: 142 IELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQR 201
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQIL 567
LE + ++ QLE +++ +E ++ E+ +E + ++ V+ + I
Sbjct: 202 SLEESQGKI-----AQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIA 256
Query: 568 RIEEQHKL---EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLH 624
++EE K EI L++ E I + Q+ K LLE + E R E L+
Sbjct: 257 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 316
Query: 625 AALQ 628
A +Q
Sbjct: 317 AEMQ 320
Score = 38.7 bits (86), Expect = 0.065
Identities = 60/281 (21%), Positives = 118/281 (41%), Gaps = 22/281 (7%)
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-------KSLEEQLNTEL 384
EN + D+ E + D KC+ L+ EK + E LN E+
Sbjct: 260 ENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEM 319
Query: 385 DNV--NVMLSNKDKEIDVLKE-NYDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDST 436
N+ +L +++E KE D++++ K+L+ + + +E + KEK +
Sbjct: 320 QNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMAKEKNLFEEEL 379
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC 496
K + EL+K Q L+ Q + KS+ E + ++ + E + + +
Sbjct: 380 KQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQAT 439
Query: 497 DFLDNEVKTLRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
L + ++ Q LE Q K ++ED L QE++ +A + E D +
Sbjct: 440 LLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN-SSLQEKVAKAGKNAE-DVQ- 496
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
+ +S N++ +R+ + + + L+E + +EI + LQ
Sbjct: 497 HQILATESSNQEYVRMLLDLQTK-SALKETEIKEITVSFLQ 536
>BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein.
Length = 552
Score = 53.6 bits (123), Expect = 2e-06
Identities = 65/275 (23%), Positives = 120/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 132 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 191
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 192 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 251
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E+ + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 252 EILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFI 311
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 312 LEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMAKEKNLFEEELKQTLDELD 371
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 372 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 406
Score = 48.0 bits (109), Expect = 1e-04
Identities = 53/234 (22%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAH 360
KL++ L++ +SL + E +L + +C + ++ K+ + FE EL +TLD
Sbjct: 319 KLQQKELQI-DSLLQQEKELSSSLHQKLCSFQ------EEMAKEKNLFEEELKQTLDELD 371
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKE---NYDTVMRLNKQLT 416
Q K +Q + K LEE+ + + + ++ K KE ++ K + + L ++
Sbjct: 372 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYD 431
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
V++LE+ + + T S I +L S+ ++ + + ++ ++ S
Sbjct: 432 SMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKVAKAGKNAEDVQHQILATESSNQ 491
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH---YQKQLED 527
+ L + Q + LK+ + + V L++ +LQ N+LK ++KQLED
Sbjct: 492 EYVRMLLDLQTK--SALKETEIKEITVSFLQKITDLQ-NQLKQQEEDFRKQLED 542
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/275 (21%), Positives = 126/275 (45%), Gaps = 21/275 (7%)
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLE 423
K ++ + +K+S ++ LN + D + K K E+ V+ + D +++LE
Sbjct: 40 KSQRFKQQKES-KQNLNVDKDTTLPASARKVKS----SESKICVLLQERGAQDRRIQDLE 94
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE--ERSRCAVIEQQ 481
LEK + ++ T L+ ++ + + LT+ +LLKSK +E + ++ +
Sbjct: 95 TELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLE 154
Query: 482 LCEKQN----QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
L + +N + ++ K + ++ +++ ++ LE + ++ QLE +++ +E
Sbjct: 155 LMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-----AQLEGKLVSIEKEKI 209
Query: 538 EQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKL---EINVLEEKQREEIKLYRL 593
++ E+ +E + ++ V+ + I ++EE K EI L++ E I +
Sbjct: 210 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSK 269
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
Q+ K LLE + E R E L+A +Q
Sbjct: 270 QVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQ 304
Score = 42.3 bits (95), Expect = 0.005
Identities = 51/246 (20%), Positives = 107/246 (43%), Gaps = 17/246 (6%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N + Q++ + + + L ++ L + S +
Sbjct: 290 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 349
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN-------LEE------ 424
E++ E + L E+D L++ + RL KQL + K+ LEE
Sbjct: 350 EEMAKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKE 409
Query: 425 -ALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
LEK AH + E + +QS+ D T + L S++ + + + +++++
Sbjct: 410 AELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKV 469
Query: 483 CEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQ-KNELKCHYQKQLEDAVLAKLQEFQEQL 540
+ +V + + + + +R L+LQ K+ LK K++ + L K+ + Q QL
Sbjct: 470 AKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQL 529
Query: 541 DRAERE 546
+ E +
Sbjct: 530 KQQEED 535
Score = 38.7 bits (86), Expect = 0.065
Identities = 60/281 (21%), Positives = 118/281 (41%), Gaps = 22/281 (7%)
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-------KSLEEQLNTEL 384
EN + D+ E + D KC+ L+ EK + E LN E+
Sbjct: 244 ENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEM 303
Query: 385 DNV--NVMLSNKDKEIDVLKE-NYDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDST 436
N+ +L +++E KE D++++ K+L+ + + +E + KEK +
Sbjct: 304 QNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMAKEKNLFEEEL 363
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC 496
K + EL+K Q L+ Q + KS+ E + ++ + E + + +
Sbjct: 364 KQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQAT 423
Query: 497 DFLDNEVKTLRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
L + ++ Q LE Q K ++ED L QE++ +A + E D +
Sbjct: 424 LLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN-SSLQEKVAKAGKNAE-DVQ- 480
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
+ +S N++ +R+ + + + L+E + +EI + LQ
Sbjct: 481 HQILATESSNQEYVRMLLDLQTK-SALKETEIKEITVSFLQ 520
>BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-coil 1
protein.
Length = 1594
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 24/269 (8%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN-VNVMLSNKDKEIDV 400
+++T + +E+ K L QD + Q L + E D ++ ++S ++E ++
Sbjct: 1094 EQETENLRTEISK---LNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNI 1150
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRI--QSVNDETLLL 457
LK + V L+ Q + KNL+E + + + DS S + + +++I Q E ++
Sbjct: 1151 LKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQ 1210
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC----DFLDNEVKTLRQHLELQ 513
E+D K ++E+ R +I++ CEK LK+ + ++ E+ +HLE Q
Sbjct: 1211 NLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQ 1270
Query: 514 -------------KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+ L Q++L++ L++ +EQ R EM+N
Sbjct: 1271 IAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT 1330
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
+FN + R + + + IN L +K + ++
Sbjct: 1331 NFNTVLTREKMRKENIINDLSDKLKSTMQ 1359
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/267 (23%), Positives = 118/267 (44%), Gaps = 26/267 (9%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEIDVLKENY 405
E + L L ++Y+ K L E + E ++L EL + +L NKD E ++K
Sbjct: 861 EKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEK 920
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
+ V+ L + ++ LE E H S I EL + + V ++ L E D
Sbjct: 921 EAVICLQNEKD------QKLLEMENIMH-SQNCEIKELKQSREIVLEDLKKLHVEND--- 970
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+ R+ +EQ ++ +V +F K + H + ELK Q+
Sbjct: 971 EKLQLLRAELQSLEQSHLKELEDTLQVRHIQEF----EKVMTDH-RVSLEELKKENQQ-- 1023
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-QI-LRIEEQHKLEINV-LEE 582
++ ++QE ++ + + + + +LK +++ D+ K ++ L ++E EI + LEE
Sbjct: 1024 ---IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEE 1080
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKV 609
+ ++ + + L Q E L SK+
Sbjct: 1081 SRAQQKETLKSLLEQETENLRTEISKL 1107
Score = 32.3 bits (70), Expect = 5.6
Identities = 38/195 (19%), Positives = 87/195 (44%), Gaps = 14/195 (7%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRH-RKALEKMICEVENFRVVADDAQKK 344
A+ +++ + +S + +L L+ +D + AL++ E E VV + +K
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLERE---VVEKELLEK 1263
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
H E+++ K+ + D + ++ L+E+ L+ + K++E+ +N
Sbjct: 1264 VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEM----QN 1319
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAH---DSTKSNITELNK---RIQSVNDETLLLT 458
T + +Q E + KE + D KS + + + I+S++++ L
Sbjct: 1320 VRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLL 1379
Query: 459 QERDLLKSKVNEERS 473
+E+ L+ +V++ RS
Sbjct: 1380 EEKKKLEEEVSKLRS 1394
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 53.6 bits (123), Expect = 2e-06
Identities = 63/311 (20%), Positives = 133/311 (42%), Gaps = 35/311 (11%)
Query: 311 NSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKC 366
NSL A D+ ++ +K++ E E + + + K++ +EL+K + + D+
Sbjct: 438 NSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL 497
Query: 367 KQLQNEKKSLEEQL----------------------NTELDNVNVMLSNKDKEIDVLKEN 404
+ ++ E K+LE+++ EL+ ++ L+ ++ E L+
Sbjct: 498 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEA-ALEHE 556
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLL 464
++R+ +LT ++ + ++ + K N + +QS D + E L
Sbjct: 557 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 616
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNELKCHYQK 523
K K+ + + IE QL Q +E LK + ++K + HL + + + Q
Sbjct: 617 KKKMEGDLNE---IEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQL 673
Query: 524 QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ + LQ E+L + E +L E ++DS N+ R++ H +++ K
Sbjct: 674 AIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NE---RVQLLHTQNTSLIHTK 729
Query: 584 QREEIKLYRLQ 594
++ E L +LQ
Sbjct: 730 KKLETDLMQLQ 740
Score = 42.7 bits (96), Expect = 0.004
Identities = 68/333 (20%), Positives = 141/333 (42%), Gaps = 44/333 (13%)
Query: 322 KALEKMICEVENFRVVADDAQKKTS----HFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
K ++ I ++EN + D+ KK +S++ L +Q K K+LQ + LE
Sbjct: 62 KLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE 121
Query: 378 EQLNTE---LDNVNVMLSNKDKEIDVLKENYD-------TVMRLNKQLTDCVKNLEEALE 427
E++ E S+ +E++ L E + T + LNK+ L LE
Sbjct: 122 EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 181
Query: 428 KEKFAHDST--------KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+ H++ ++ EL ++I ++ L +E+ K ++++ S +
Sbjct: 182 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 241
Query: 480 QQLCEKQNQC---SEVLKKCDFLDNEVKTLRQHLELQKNELKC---HYQKQLE--DAVLA 531
+ + C + L + + E++ L QK+ L+ +QLE +++++
Sbjct: 242 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 301
Query: 532 KL----QEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L Q F +Q + +R++E + + K + + S + EQ+ EE+Q
Sbjct: 302 QLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY-------EEEQE 354
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ +L R L++A ++ +K E +R E
Sbjct: 355 GKAELQR-ALSKANSEVAQWRTKYETDAIQRTE 386
Score = 39.5 bits (88), Expect = 0.037
Identities = 52/289 (17%), Positives = 124/289 (42%), Gaps = 11/289 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
+KK + +EL + +D + K ++ ++E K + L++ +++V+ +N +K L
Sbjct: 195 RKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTL 254
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ N+++ + L + + + E + ++ TQ+
Sbjct: 255 EDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQT 314
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHY 521
+ LK ++ EE + L ++ C ++L++ + E K Q + N +
Sbjct: 315 EELKRQLEEENKAKNALAHALQSSRHDC-DLLREQYEEEQEGKAELQRALSKANSEVAQW 373
Query: 522 QKQLEDAVLAKLQEFQEQLDR-AEREMENDARLKENNI-VDSFNKQILRIEEQHKLEINV 579
+ + E + + +E +E + A+R +++ +++ N S K R+ Q ++E ++
Sbjct: 374 RTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRL--QGEVE-DL 430
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ + +R L Q L E K +C+ E+ A L A+L+
Sbjct: 431 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCE-----ESQAELEASLK 474
Score = 38.7 bits (86), Expect = 0.065
Identities = 30/112 (26%), Positives = 61/112 (54%), Gaps = 7/112 (6%)
Query: 515 NELKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQILRIEE 571
N+ K ++Q+ED + L + ++ + L+R +R++E D +L + +I+D N KQ L
Sbjct: 23 NKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERL 82
Query: 572 QHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGET 619
+ K E L+ K +E L ++ ++ + ++ LE ++E +R R +T
Sbjct: 83 KKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKT 134
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/303 (18%), Positives = 137/303 (45%), Gaps = 20/303 (6%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++++ D ++ ++E + L+ + K+ E+++ E R + + + + FE
Sbjct: 1162 QIEKLSDKVVASVKEG---VQGPLNVSLSEEGKSQEQIL---EILRFIRREKEIAETRFE 1215
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK--ENYDT 407
++L Y+ + + L+ E + L++ LN E + V V + +++K E +
Sbjct: 1216 VAQVESLR----YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNV 1271
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
VM NK L + + LE+ L++ + + +I L + +++++ +L E+ LL+
Sbjct: 1272 VMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Query: 468 VNEERSRCA-VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
V ++R ++ QQ + ++L + + ++ L + + K E+
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-----QILRIEEQHKLEINVLE 581
+ L +Q +E L++ E E + + I+D K Q+ +I ++K + L+
Sbjct: 1392 NQNL--IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK 1449
Query: 582 EKQ 584
+Q
Sbjct: 1450 AQQ 1452
Score = 48.4 bits (110), Expect = 8e-05
Identities = 67/333 (20%), Positives = 144/333 (43%), Gaps = 34/333 (10%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV----VADDAQKKTSHFESELYKT 355
++L + + + +D R+A+E M ++ + V ++ Q+ + L
Sbjct: 1002 TQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLN 412
D Q++ K + E +L +V + + K+ K V + +T +
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAE 1121
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV--NE 470
QL +C + EE +E+ D + R + + + LL + + L KV +
Sbjct: 1122 SQLLECKASWEE---RERMLKDEVSKCVC----RCEDLEKQNRLLHDQIEKLSDKVVASV 1174
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+ + L E+ ++L+ F+ E + E+ + E Y++++E +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVE-SLRYRQRVE-LLE 1232
Query: 531 AKLQEFQEQLDRAEREM---------ENDARLKEN---NIVDSFNKQILRIEEQHKLEIN 578
+LQE Q+ L+ AERE +++ +K+ N+V NK + +E+ + ++
Sbjct: 1233 RELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 579 VLEEKQRE-EIKLYRLQLAQA--AEKLGLLESK 608
++ K R+ E+ + LQ A A +EK G+L+++
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Score = 45.2 bits (102), Expect = 7e-04
Identities = 70/377 (18%), Positives = 154/377 (40%), Gaps = 40/377 (10%)
Query: 218 QNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXX 277
Q + I+T+ DL +E R + + +++KL E RL ++ E+++
Sbjct: 756 QEQIINTMTQDLRGANEKLAVAEVRAENLKK--EKEMLKLSEVRLSQQR-ESLLAEQRGQ 812
Query: 278 XXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ ++R++ +L +L + + + + +E+ N V
Sbjct: 813 NLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQ 872
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE-------------- 383
D +++ + T +L + Q + L+ ++E Q+ ++
Sbjct: 873 LLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Query: 384 -LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-- 440
+D++ L +++++ LKE T +Q V +LEE+L KEK + + NI
Sbjct: 933 DVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Query: 441 ---------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
T+L K++ V E L ++ + + + + +++ L QN+ E
Sbjct: 993 RLKESAEFQTQLEKKLMEVEKEKQELQDDK---RRAIESMEQQLSELKKTLSSVQNEVQE 1049
Query: 492 VLKKCD-FLDNEVKTLRQHLELQK--NELKCHYQKQ--LEDAVLAKLQEFQEQLDR---A 543
L++ L NE + R E K E + Y+++ L A + LQ +EQ+ +
Sbjct: 1050 ALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV 1109
Query: 544 EREMENDARLKENNIVD 560
+ +E + E+ +++
Sbjct: 1110 RQHLEETTQKAESQLLE 1126
Score = 41.1 bits (92), Expect = 0.012
Identities = 61/306 (19%), Positives = 124/306 (40%), Gaps = 19/306 (6%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT-ELDNVN 388
E E Q K E ++ + + +K LQ EKK LEE + + N +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 389 VMLSNKDKEID----VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
++ KD + + +L E R+ +QLT+ + L+ + + + + ++ I L
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTKRI-QQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD-FLDNEV 503
+ + V E + ++ D + E+ +++ + Q E+ + D ++
Sbjct: 1401 EDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSA 1460
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER---EMENDAR-LKENNIV 559
++ H E + + K+ + K + + Q++ ++ E E +AR L+E +
Sbjct: 1461 QSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 560 DSFNKQILRI--------EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
LR EEQ + +I EEK R+ I + ++A A L + E
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEE 1580
Query: 612 QRRRRG 617
++R G
Sbjct: 1581 LKQRNG 1586
Score = 39.9 bits (89), Expect = 0.028
Identities = 66/297 (22%), Positives = 130/297 (43%), Gaps = 37/297 (12%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
C +EN + +++ + ++ D K K+ + ++ S+EE+ + EL N +
Sbjct: 224 CNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 389 VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ LSN + K D + +LT V+ L + L++ A+ + + ++ E+ +
Sbjct: 283 IKLSN------LYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336
Query: 449 SVNDETL----LLTQERDLLKSKVNEERSRCAVI-EQQLCEKQNQCSEVLK------KCD 497
+ E L L +E + ++ + + A++ E++L + V K K
Sbjct: 337 QMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLT 396
Query: 498 FLDNEVKTLRQHLELQKNELK--CHYQKQLEDAVLAK---LQEFQEQLDRA--------- 543
L N + L L+K E K Y ++ V AK L+ +E+ +RA
Sbjct: 397 ELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSV 456
Query: 544 --EREMENDARLKENNIVDSFNKQILRIE-EQHKLEINVLEEKQREEIKLYRLQLAQ 597
E+ M+ RL+E+ D NKQ +E + ++EI V + Q+ + L L+ A+
Sbjct: 457 KLEQAMKEIQRLQED--TDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 511
Score = 39.5 bits (88), Expect = 0.037
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNI---TELNKRIQSVN 451
+E+ LKE + +K L V+NL++ L EKE A + + + +EL++ Q +
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
D T Q R + K EE++R A++ + K + V + + E+K L+
Sbjct: 1534 DRTTQEEQLRQQITEK--EEKTRKAIVAAK--SKIAHLAGVKDQLTKENEELKQRNGALD 1589
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQL-DRAEREME-NDARLKENNIVDSFNKQI 566
QK+EL L+ ++ + +L + ER +E D + +N V +QI
Sbjct: 1590 QQKDELDVRI-TALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQI 1645
Score = 35.1 bits (77), Expect = 0.80
Identities = 54/277 (19%), Positives = 120/277 (43%), Gaps = 26/277 (9%)
Query: 367 KQLQNEKKSLEEQLNTELDNVN-----VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
K +QN+ + +E+D + + ++ + ++ K + RL + +C ++
Sbjct: 19 KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETREC-QS 77
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
L LEK ++ K+ +TE NK ++ D + + + K ++ E+ ++
Sbjct: 78 LRLELEK---LNNQLKA-LTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER 133
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH--YQKQLEDAVLAKLQEFQEQ 539
L ++ +E +K+ + E T + L+L+ +EL+ K E +L++ +E
Sbjct: 134 LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE----KRLEQEKEL 189
Query: 540 LDRAEREMENDARLKENNIV---DSFNKQILRIE---EQHKLEINVLEEKQREEIKLYRL 593
L + + + K + ++ +IL ++ E K E++ LEE Q +K
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE-QMNGLKTSNE 248
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L + E L +K++ + ++ + H L AH
Sbjct: 249 HLQKHVED---LLTKLKEAKEQQASMEEKFHNELNAH 282
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 53.6 bits (123), Expect = 2e-06
Identities = 82/329 (24%), Positives = 156/329 (47%), Gaps = 42/329 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 141 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 200
Query: 353 YKTLDLAHDYQDKCKQ-LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
K ++ +D Q L +K+ L E+L ++ + N+D + VLKE+ + +++
Sbjct: 201 LKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKES-EVLLQ- 258
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
K E LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 259 -------AKRAE--LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQ 307
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLA 531
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L
Sbjct: 308 EA------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLI 355
Query: 532 K--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
K +++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +
Sbjct: 356 KQEIEKEEENLQVVLRQMSKH-KTELKNILD-----MLQL-ENHELQGLKLQHDQRVS-E 407
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGE 618
L + Q+A EKL LE+ + ++++GE
Sbjct: 408 LEKTQVAVLEEKLE-LENLQQISQQQKGE 435
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/272 (22%), Positives = 124/272 (45%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 303 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 361
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ +KN+ + L+ E K ++EL K +V +E L
Sbjct: 362 EEENLQVVLRQMSKHKTE-LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 420
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 421 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 480
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L VLA +E + ++E + R K +D N+ L +
Sbjct: 481 WEKKL------AQTKRVLAAAEENSKMEQSNLEKLELNVR-KLQQELDQLNRDKLSLHND 533
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 534 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 564
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 633 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 692
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 693 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 746
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 747 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 804
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 805 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 863
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 864 LPADLEAILERNENLEGE 881
Score = 40.3 bits (90), Expect = 0.021
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 345 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ-----LENHELQGLKL 399
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 400 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 455
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETLLLT--- 458
++ L CV K E+ EK +K A E N +++ N E L L
Sbjct: 456 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRK 515
Query: 459 --QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 516 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 568
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 569 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 619
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 620 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 657
Score = 38.3 bits (85), Expect = 0.085
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT----VMRLNKQLTDCVKN- 421
KQL K E++ E + + KE + L+E D + + + L +N
Sbjct: 440 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 499
Query: 422 -LEEA-LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+E++ LEK + + + +LN+ S++++ + Q+ + VN + A ++
Sbjct: 500 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 559
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK-CHYQKQLEDAVLAKLQ-EFQ 537
L + K D L +E L++ + N + C +++ + L LQ E +
Sbjct: 560 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 619
Query: 538 E-QLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
E +L ++EM KE +S ++ E+QH+LE + ++K + + L ++
Sbjct: 620 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 679
Query: 595 LAQ 597
A+
Sbjct: 680 AAE 682
Score = 33.9 bits (74), Expect = 1.8
Identities = 60/245 (24%), Positives = 112/245 (45%), Gaps = 29/245 (11%)
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK----FAHDSTKSNITELN-----K 445
+KE++ L N D +++ K L V+ L ++K + F + +S +TEL K
Sbjct: 22 EKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLK 81
Query: 446 RIQSVNDETLLLTQERDLLK--SKVNEERSRCAVIEQQL-CEKQNQC-------SEVLKK 495
+ + DE + E+ LLK S++ E A E +L C K+ C S V K
Sbjct: 82 HHEDIVDEIECI--EKTLLKRRSELREADRLLAEAESELSCTKEKVCLLVVWGVSSVWTK 139
Query: 496 CDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKE 555
+ ++ R L+ + + + + Q L K + L +++E ++K+
Sbjct: 140 -NAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQH-KIKQ 197
Query: 556 NNIVDSFNKQILRIEEQHKLEINVLEEKQREEI-KLYR-LQLAQAAE--KLGLL-ESKVE 610
I+ NK I+ ++ ++ +EK EE+ KL + +++A+ E L +L ES+V
Sbjct: 198 EEILKEINK-IVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVL 256
Query: 611 CQRRR 615
Q +R
Sbjct: 257 LQAKR 261
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 53.6 bits (123), Expect = 2e-06
Identities = 80/328 (24%), Positives = 155/328 (47%), Gaps = 40/328 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 907 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 966
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
K ++ +D Q ++KK E+L EL + K+I++ + N D +++
Sbjct: 967 LKEINKIVAAKDSDFQCLSKKK---EKLTEELQKLQ-------KDIEMAERNEDHHLQVL 1016
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 1017 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQE 1074
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK 532
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L K
Sbjct: 1075 A------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLIK 1122
Query: 533 --LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
+++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +L
Sbjct: 1123 QEIEKEEENLQVVLRQMSKH-KTELKNILD-----MLQL-ENHELQGLKLQHDQRVS-EL 1174
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ Q+A EKL LE+ + ++++GE
Sbjct: 1175 EKTQVAVLEEKLE-LENLQQISQQQKGE 1201
Score = 52.0 bits (119), Expect = 6e-06
Identities = 76/317 (23%), Positives = 136/317 (42%), Gaps = 22/317 (6%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
S+L E R+ + +D + E I E + D + S + L A
Sbjct: 24 SRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALK---KDLEGVISGLQEYLGTIKGQA 80
Query: 360 HDYQDKCKQLQNEKKSL------EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
Q++C++L++EK++L EQ +L+ V + N KE+ L+ +N
Sbjct: 81 TQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNA 140
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
L +L A E E A + + E N+ + + T L E+ L++++ +ER
Sbjct: 141 SLQQTQGDL-SAYEAELEARLNLRD--AEANQLKEELEKVTRLTQLEQSALQAELEKERQ 197
Query: 474 --RCAVIEQQLC-EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDA 528
+ A+ + Q EK+ + SE+ K L ++ L+Q L+ +N L H L +
Sbjct: 198 ALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN-HVVDGLVRPEE 256
Query: 529 VLAKLQEFQEQLDRAEREME----NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
V A++ E + +L EM +D K + +IL + + E V E K
Sbjct: 257 VAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKL 316
Query: 585 REEIKLYRLQLAQAAEK 601
+EE+ L + +LA E+
Sbjct: 317 QEEMALQQEKLATGQEE 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/272 (22%), Positives = 124/272 (45%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 1069 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 1127
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ +KN+ + L+ E K ++EL K +V +E L
Sbjct: 1128 EEENLQVVLRQMSKHKTE-LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 1186
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 1187 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 1246
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L VLA +E + ++E + R K +D N+ L +
Sbjct: 1247 WEKKL------AQTKRVLAAAEENSKMEQSNLEKLELNVR-KLQQELDQLNRDKLSLHND 1299
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 1300 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 1330
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 1399 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 1458
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 1459 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 1512
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 1513 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 1570
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 1571 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 1629
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 1630 LPADLEAILERNENLEGE 1647
Score = 40.3 bits (90), Expect = 0.021
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 1111 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ-----LENHELQGLKL 1165
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 1166 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 1221
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETLLLT--- 458
++ L CV K E+ EK +K A E N +++ N E L L
Sbjct: 1222 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRK 1281
Query: 459 --QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 1282 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 1334
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 1335 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 1385
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 1386 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 1423
Score = 39.1 bits (87), Expect = 0.049
Identities = 72/350 (20%), Positives = 142/350 (40%), Gaps = 35/350 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
+DA ++L+E ++T + + LEK ++N A +++K SEL+
Sbjct: 163 RDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE-NSELHA 221
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN---------- 404
L QD L+ + K + LN +D + V +D L+
Sbjct: 222 KLK---HLQDDNNLLKQQLKDFQNHLNHVVDGL-VRPEEVAARVDELRRKLKLGTGEMNI 277
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER--- 461
+ L K L D K E L + K+ D + +L + + ++ E L QE
Sbjct: 278 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEM-ALQQEKLATGQEEFRQ 336
Query: 462 ---DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL- 517
L++++N ++ + QQ+ + + E LK + + Q + +K +
Sbjct: 337 ACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIL 396
Query: 518 ----KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +K+LEDA K QE LD+ ++++ + +++ H
Sbjct: 397 AQLRELEKKKKLEDA---KSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLH 453
Query: 574 KLEINVLEEKQRE--EIKLYRLQLAQAAEKLGLLESKVECQR---RRRGE 618
+ + +E+ E E + + + AQAA L E+++E + R++GE
Sbjct: 454 GTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGE 503
Score = 38.3 bits (85), Expect = 0.085
Identities = 54/266 (20%), Positives = 123/266 (46%), Gaps = 15/266 (5%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
H+ +++ +L++ + L+ + E + +KE++ L N D +++ K L V
Sbjct: 767 HNLENEVSRLEDIMQHLKSKKREERW-MRASKRQSEKEMEELHHNIDDLLQEKKSLECEV 825
Query: 420 KNLEEALEKEK----FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ L ++K + F + +S +TEL + E ++ E + ++ + + RS
Sbjct: 826 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIV--DEIECIEKTLLKRRSEL 883
Query: 476 AVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
++ L E +++ S +K + ++ R L+ + + + + Q L K
Sbjct: 884 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 943
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI-KLYR- 592
+ L +++E ++K+ I+ NK I+ ++ ++ +EK EE+ KL +
Sbjct: 944 QQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAAKDSDFQCLSKKKEKLTEELQKLQKD 1001
Query: 593 LQLAQAAE--KLGLL-ESKVECQRRR 615
+++A+ E L +L ES+V Q +R
Sbjct: 1002 IEMAERNEDHHLQVLKESEVLLQAKR 1027
Score = 38.3 bits (85), Expect = 0.085
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT----VMRLNKQLTDCVKN- 421
KQL K E++ E + + KE + L+E D + + + L +N
Sbjct: 1206 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 1265
Query: 422 -LEEA-LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+E++ LEK + + + +LN+ S++++ + Q+ + VN + A ++
Sbjct: 1266 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 1325
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK-CHYQKQLEDAVLAKLQ-EFQ 537
L + K D L +E L++ + N + C +++ + L LQ E +
Sbjct: 1326 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 1385
Query: 538 E-QLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
E +L ++EM KE +S ++ E+QH+LE + ++K + + L ++
Sbjct: 1386 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 1445
Query: 595 LAQ 597
A+
Sbjct: 1446 AAE 1448
Score = 37.5 bits (83), Expect = 0.15
Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 16/157 (10%)
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
+++ +N + L D + S++ +E +E+QL E Q +E LKK L+ +
Sbjct: 10 QQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK--DLEGVIS 67
Query: 505 TLRQHLELQKNEL-----KCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNI 558
L+++L K + +C + ++ +L +L E +++ D+ E M+ + KE
Sbjct: 68 GLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE 127
Query: 559 VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL 595
++S ++EQH E+N ++ + ++ Y +L
Sbjct: 128 LES------ALQEQH--EVNASLQQTQGDLSAYEAEL 156
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 53.6 bits (123), Expect = 2e-06
Identities = 80/328 (24%), Positives = 155/328 (47%), Gaps = 40/328 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 1459 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 1518
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
K ++ +D Q ++KK E+L EL + K+I++ + N D +++
Sbjct: 1519 LKEINKIVAAKDSDFQCLSKKK---EKLTEELQKLQ-------KDIEMAERNEDHHLQVL 1568
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 1569 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQE 1626
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK 532
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L K
Sbjct: 1627 A------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLIK 1674
Query: 533 --LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
+++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +L
Sbjct: 1675 QEIEKEEENLQVVLRQMSKH-KTELKNILD-----MLQL-ENHELQGLKLQHDQRVS-EL 1726
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ Q+A EKL LE+ + ++++GE
Sbjct: 1727 EKTQVAVLEEKLE-LENLQQISQQQKGE 1753
Score = 47.6 bits (108), Expect = 1e-04
Identities = 59/279 (21%), Positives = 129/279 (46%), Gaps = 32/279 (11%)
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL------DNVNVMLS 392
+D +KK S ++ L + D + + + E K LEE + + D + LS
Sbjct: 440 EDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLS 499
Query: 393 NKDKEIDVLK-ENYDTVMRLNKQLTDC------VKNLE---EALEKEKFAHDSTKSNITE 442
+ + ++ L+ E D +++ KQ + +K+L+ ++L+ + H K+ +
Sbjct: 500 GRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSG 559
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
+++ +N + L D + S++ +E +E+QL E Q +E LKK L+
Sbjct: 560 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK--DLEGV 617
Query: 503 VKTLRQHLELQKNEL-----KCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKEN 556
+ L+++L K + +C + ++ +L +L E +++ D+ E M+ + KE
Sbjct: 618 ISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKEL 677
Query: 557 NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL 595
++S ++EQH E+N ++ + ++ Y +L
Sbjct: 678 AELES------ALQEQH--EVNASLQQTQGDLSAYEAEL 708
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/272 (22%), Positives = 124/272 (45%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 1621 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 1679
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ +KN+ + L+ E K ++EL K +V +E L
Sbjct: 1680 EEENLQVVLRQMSKHKTE-LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 1738
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 1739 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 1798
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L VLA +E + ++E + R K +D N+ L +
Sbjct: 1799 WEKKL------AQTKRVLAAAEENSKMEQSNLEKLELNVR-KLQQELDQLNRDKLSLHND 1851
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 1852 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 1882
Score = 43.6 bits (98), Expect = 0.002
Identities = 63/285 (22%), Positives = 130/285 (45%), Gaps = 31/285 (10%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNV------NVMLSNKDKEIDV----LKENYDTVMRLNK 413
D + +Q +K +EQL + N+ + L +K+K+I L E +D + + +
Sbjct: 406 DSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQ 465
Query: 414 QL---TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
Q+ T+ K LEEA++ +K + +L+ R+Q VN L QE L+ ++ +
Sbjct: 466 QILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNK----LRQEALDLELQMEK 521
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE---D 527
++ A ++++ + Q + K D + +K + E Q + + YQ QLE D
Sbjct: 522 QKQEIAGKQKEIKDLQIAIDSLDSK-DPKHSHMKAQKSGKEQQLDIMNKQYQ-QLESRLD 579
Query: 528 AVLAKLQEFQEQLDRAEREM------ENDARLKE-NNIVDSFNKQILRIEEQHKLEINVL 580
+L+++ + E++ E ++ N+A K+ ++ + + I+ Q N
Sbjct: 580 EILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNEC 639
Query: 581 EE-KQREEIKLYRL-QLAQAAEKLGLLESKVECQRRRRGETAARL 623
+ + +E L RL ++ Q ++L ++ E R+ E + L
Sbjct: 640 RKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESAL 684
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 1951 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 2010
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 2011 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 2064
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 2065 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 2122
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 2123 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 2181
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 2182 LPADLEAILERNENLEGE 2199
Score = 40.3 bits (90), Expect = 0.021
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 1663 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ-----LENHELQGLKL 1717
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 1718 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 1773
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETLLLT--- 458
++ L CV K E+ EK +K A E N +++ N E L L
Sbjct: 1774 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRK 1833
Query: 459 --QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 1834 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 1886
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 1887 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 1937
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 1938 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 1975
Score = 39.1 bits (87), Expect = 0.049
Identities = 72/350 (20%), Positives = 142/350 (40%), Gaps = 35/350 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
+DA ++L+E ++T + + LEK ++N A +++K SEL+
Sbjct: 715 RDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE-NSELHA 773
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN---------- 404
L QD L+ + K + LN +D + V +D L+
Sbjct: 774 KLK---HLQDDNNLLKQQLKDFQNHLNHVVDGL-VRPEEVAARVDELRRKLKLGTGEMNI 829
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER--- 461
+ L K L D K E L + K+ D + +L + + ++ E L QE
Sbjct: 830 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEM-ALQQEKLATGQEEFRQ 888
Query: 462 ---DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL- 517
L++++N ++ + QQ+ + + E LK + + Q + +K +
Sbjct: 889 ACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIL 948
Query: 518 ----KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +K+LEDA K QE LD+ ++++ + +++ H
Sbjct: 949 AQLRELEKKKKLEDA---KSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLH 1005
Query: 574 KLEINVLEEKQRE--EIKLYRLQLAQAAEKLGLLESKVECQR---RRRGE 618
+ + +E+ E E + + + AQAA L E+++E + R++GE
Sbjct: 1006 GTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGE 1055
Score = 38.3 bits (85), Expect = 0.085
Identities = 54/266 (20%), Positives = 123/266 (46%), Gaps = 15/266 (5%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
H+ +++ +L++ + L+ + E + +KE++ L N D +++ K L V
Sbjct: 1319 HNLENEVSRLEDIMQHLKSKKREERW-MRASKRQSEKEMEELHHNIDDLLQEKKSLECEV 1377
Query: 420 KNLEEALEKEK----FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ L ++K + F + +S +TEL + E ++ E + ++ + + RS
Sbjct: 1378 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIV--DEIECIEKTLLKRRSEL 1435
Query: 476 AVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
++ L E +++ S +K + ++ R L+ + + + + Q L K
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI-KLYR- 592
+ L +++E ++K+ I+ NK I+ ++ ++ +EK EE+ KL +
Sbjct: 1496 QQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAAKDSDFQCLSKKKEKLTEELQKLQKD 1553
Query: 593 LQLAQAAE--KLGLL-ESKVECQRRR 615
+++A+ E L +L ES+V Q +R
Sbjct: 1554 IEMAERNEDHHLQVLKESEVLLQAKR 1579
Score = 38.3 bits (85), Expect = 0.085
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT----VMRLNKQLTDCVKN- 421
KQL K E++ E + + KE + L+E D + + + L +N
Sbjct: 1758 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 1817
Query: 422 -LEEA-LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+E++ LEK + + + +LN+ S++++ + Q+ + VN + A ++
Sbjct: 1818 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 1877
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK-CHYQKQLEDAVLAKLQ-EFQ 537
L + K D L +E L++ + N + C +++ + L LQ E +
Sbjct: 1878 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 1937
Query: 538 E-QLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
E +L ++EM KE +S ++ E+QH+LE + ++K + + L ++
Sbjct: 1938 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 1997
Query: 595 LAQ 597
A+
Sbjct: 1998 AAE 2000
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/303 (18%), Positives = 137/303 (45%), Gaps = 20/303 (6%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++++ D ++ ++E + L+ + K+ E+++ E R + + + + FE
Sbjct: 1162 QIEKLSDKVVASVKEG---VQGPLNVSLSEEGKSQEQIL---EILRFIRREKEIAETRFE 1215
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK--ENYDT 407
++L Y+ + + L+ E + L++ LN E + V V + +++K E +
Sbjct: 1216 VAQVESLR----YRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNV 1271
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
VM NK L + + LE+ L++ + + +I L + +++++ +L E+ LL+
Sbjct: 1272 VMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEED 1331
Query: 468 VNEERSRCA-VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
V ++R ++ QQ + ++L + + ++ L + + K E+
Sbjct: 1332 VKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTN 1391
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-----QILRIEEQHKLEINVLE 581
+ L +Q +E L++ E E + + I+D K Q+ +I ++K + L+
Sbjct: 1392 NQNL--IQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELK 1449
Query: 582 EKQ 584
+Q
Sbjct: 1450 AQQ 1452
Score = 48.4 bits (110), Expect = 8e-05
Identities = 67/333 (20%), Positives = 144/333 (43%), Gaps = 34/333 (10%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV----VADDAQKKTSHFESELYKT 355
++L + + + +D R+A+E M ++ + V ++ Q+ + L
Sbjct: 1002 TQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNE 1061
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKD---KEIDVLKENYDTVMRLN 412
D Q++ K + E +L +V + + K+ K V + +T +
Sbjct: 1062 QQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAE 1121
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV--NE 470
QL +C + EE +E+ D + R + + + LL + + L KV +
Sbjct: 1122 SQLLECKASWEE---RERMLKDEVSKCVC----RCEDLEKQNRLLHDQIEKLSDKVVASV 1174
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
+ + L E+ ++L+ F+ E + E+ + E Y++++E +
Sbjct: 1175 KEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVE-SLRYRQRVE-LLE 1232
Query: 531 AKLQEFQEQLDRAEREM---------ENDARLKEN---NIVDSFNKQILRIEEQHKLEIN 578
+LQE Q+ L+ AERE +++ +K+ N+V NK + +E+ + ++
Sbjct: 1233 RELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 579 VLEEKQRE-EIKLYRLQLAQA--AEKLGLLESK 608
++ K R+ E+ + LQ A A +EK G+L+++
Sbjct: 1292 QMQAKVRKLELDILPLQEANAELSEKSGMLQAE 1324
Score = 45.2 bits (102), Expect = 7e-04
Identities = 70/377 (18%), Positives = 154/377 (40%), Gaps = 40/377 (10%)
Query: 218 QNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXX 277
Q + I+T+ DL +E R + + +++KL E RL ++ E+++
Sbjct: 756 QEQIINTMTQDLRGANEKLAVAEVRAENLKK--EKEMLKLSEVRLSQQR-ESLLAEQRGQ 812
Query: 278 XXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVV 337
+ ++R++ +L +L + + + + +E+ N V
Sbjct: 813 NLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQ 872
Query: 338 ADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTE-------------- 383
D +++ + T +L + Q + L+ ++E Q+ ++
Sbjct: 873 LLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Query: 384 -LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-- 440
+D++ L +++++ LKE T +Q V +LEE+L KEK + + NI
Sbjct: 933 DVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEV 992
Query: 441 ---------TELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
T+L K++ V E L ++ + + + + +++ L QN+ E
Sbjct: 993 RLKESAEFQTQLEKKLMEVEKEKQELQDDK---RRAIESMEQQLSELKKTLSSVQNEVQE 1049
Query: 492 VLKKCD-FLDNEVKTLRQHLELQK--NELKCHYQKQ--LEDAVLAKLQEFQEQLDR---A 543
L++ L NE + R E K E + Y+++ L A + LQ +EQ+ +
Sbjct: 1050 ALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASV 1109
Query: 544 EREMENDARLKENNIVD 560
+ +E + E+ +++
Sbjct: 1110 RQHLEETTQKAESQLLE 1126
Score = 41.1 bits (92), Expect = 0.012
Identities = 61/306 (19%), Positives = 124/306 (40%), Gaps = 19/306 (6%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT-ELDNVN 388
E E Q K E ++ + + +K LQ EKK LEE + + N +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 389 VMLSNKDKEID----VLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN 444
++ KD + + +L E R+ +QLT+ + L+ + + + + ++ I L
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTKRI-QQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD-FLDNEV 503
+ + V E + ++ D + E+ +++ + Q E+ + D ++
Sbjct: 1401 EDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSA 1460
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER---EMENDAR-LKENNIV 559
++ H E + + K+ + K + + Q++ ++ E E +AR L+E +
Sbjct: 1461 QSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 560 DSFNKQILRI--------EEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
LR EEQ + +I EEK R+ I + ++A A L + E
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEE 1580
Query: 612 QRRRRG 617
++R G
Sbjct: 1581 LKQRNG 1586
Score = 39.9 bits (89), Expect = 0.028
Identities = 66/297 (22%), Positives = 130/297 (43%), Gaps = 37/297 (12%)
Query: 329 CEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVN 388
C +EN + +++ + ++ D K K+ + ++ S+EE+ + EL N +
Sbjct: 224 CNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNEL-NAH 282
Query: 389 VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ LSN + K D + +LT V+ L + L++ A+ + + ++ E+ +
Sbjct: 283 IKLSN------LYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336
Query: 449 SVNDETL----LLTQERDLLKSKVNEERSRCAVI-EQQLCEKQNQCSEVLK------KCD 497
+ E L L +E + ++ + + A++ E++L + V K K
Sbjct: 337 QMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLT 396
Query: 498 FLDNEVKTLRQHLELQKNELK--CHYQKQLEDAVLAK---LQEFQEQLDRA--------- 543
L N + L L+K E K Y ++ V AK L+ +E+ +RA
Sbjct: 397 ELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSV 456
Query: 544 --EREMENDARLKENNIVDSFNKQILRIE-EQHKLEINVLEEKQREEIKLYRLQLAQ 597
E+ M+ RL+E+ D NKQ +E + ++EI V + Q+ + L L+ A+
Sbjct: 457 KLEQAMKEIQRLQED--TDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEAR 511
Score = 39.5 bits (88), Expect = 0.037
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 396 KEIDVLKENYDTVMRLNKQLTDCVKNLEEAL-EKEKFAHDSTKSNI---TELNKRIQSVN 451
+E+ LKE + +K L V+NL++ L EKE A + + + +EL++ Q +
Sbjct: 1474 QEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
D T Q R + K EE++R A++ + K + V + + E+K L+
Sbjct: 1534 DRTTQEEQLRQQITEK--EEKTRKAIVAAK--SKIAHLAGVKDQLTKENEELKQRNGALD 1589
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQL-DRAEREME-NDARLKENNIVDSFNKQI 566
QK+EL L+ ++ + +L + ER +E D + +N V +QI
Sbjct: 1590 QQKDELDVRI-TALKSQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQI 1645
Score = 35.1 bits (77), Expect = 0.80
Identities = 54/277 (19%), Positives = 120/277 (43%), Gaps = 26/277 (9%)
Query: 367 KQLQNEKKSLEEQLNTELDNVN-----VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN 421
K +QN+ + +E+D + + ++ + ++ K + RL + +C ++
Sbjct: 19 KSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETREC-QS 77
Query: 422 LEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQ 481
L LEK ++ K+ +TE NK ++ D + + + K ++ E+ ++
Sbjct: 78 LRLELEK---LNNQLKA-LTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER 133
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH--YQKQLEDAVLAKLQEFQEQ 539
L ++ +E +K+ + E T + L+L+ +EL+ K E +L++ +E
Sbjct: 134 LSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYRE----KRLEQEKEL 189
Query: 540 LDRAEREMENDARLKENNIV---DSFNKQILRIE---EQHKLEINVLEEKQREEIKLYRL 593
L + + + K + ++ +IL ++ E K E++ LEE Q +K
Sbjct: 190 LHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEE-QMNGLKTSNE 248
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
L + E L +K++ + ++ + H L AH
Sbjct: 249 HLQKHVED---LLTKLKEAKEQQASMEEKFHNELNAH 282
>AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens
cDNA FLJ40198 fis, clone TESTI2019975, weakly similar to
TRICHOHYALIN. ).
Length = 621
Score = 53.6 bits (123), Expect = 2e-06
Identities = 68/341 (19%), Positives = 152/341 (44%), Gaps = 24/341 (7%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN-- 371
DR + K + + E+ + ++ ++K + + +L + Q K+L+
Sbjct: 186 DRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKL 245
Query: 372 EKKSL---EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEK 428
E+ L ++QL E D++ L + ++ E + RLN+Q + + EE +++
Sbjct: 246 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 305
Query: 429 EKFAHDSTKSNITELNKRIQSVND-----ETLLLTQERDLLKSK--VNEERSRCAVIEQQ 481
+ + I E ++I+ + E ++ +E + + + + E+ + +E+
Sbjct: 306 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 365
Query: 482 LCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQ 539
+ EK+ + E+ +K +E + +R+ E ++ E K Q +Q ++A + + +E +
Sbjct: 366 MWEKEEKIRELEEKM----HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 421
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEE--QHKLEINVLEEKQREEIKLYR-LQLA 596
+ RE E +E I ++ +R EE Q + E+ EEK RE+ +++R +
Sbjct: 422 QEEKIREQEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM 478
Query: 597 QAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALRI 637
EK+ E KV Q + + ++ + WR +I
Sbjct: 479 HEQEKIWKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 519
Score = 50.8 bits (116), Expect = 1e-05
Identities = 74/390 (18%), Positives = 170/390 (43%), Gaps = 27/390 (6%)
Query: 255 IKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLD 314
I+L + LKR+ A + ++ AK A + E W RL +
Sbjct: 234 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 293
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
R + +++ +++ + ++K E ++ + ++ + ++K ++ +
Sbjct: 294 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 353
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
EE++ + M+ K+++I L+E ++ +Q + + E+ E+EK
Sbjct: 354 EKEEKMR----RLEEMMWEKEEKIRELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQ 408
Query: 435 STK-----SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ-QLCEKQNQ 488
K I E ++I+ ++ + +E+ + K+ EE R E + EK +
Sbjct: 409 EAKMWRQEEKIREQEEKIRE-QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 467
Query: 489 CSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM- 547
E+ ++ + + + K +Q ++ + E K H Q++ K++E +E++ R E ++
Sbjct: 468 QEEIWRQKEKMHEQEKIWKQEEKVWRQEEKMHDQEE-------KIREQEEKMWRQEEKIR 520
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
E + +++E + +Q +I EQ + +I EEK RE+ ++ + Q EK+ E
Sbjct: 521 EQEEKIREQE--EKIREQKEKIREQEE-KIWEQEEKIREQEEMMQEQ----EEKMWEQEE 573
Query: 608 KVECQRRRRGETAARLHAALQAHWRHALRI 637
K+ Q + E ++ + W +R+
Sbjct: 574 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 603
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 53.6 bits (123), Expect = 2e-06
Identities = 80/328 (24%), Positives = 155/328 (47%), Gaps = 40/328 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 927 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 986
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
K ++ +D Q ++KK E+L EL + K+I++ + N D +++
Sbjct: 987 LKEINKIVAAKDSDFQCLSKKK---EKLTEELQKLQ-------KDIEMAERNEDHHLQVL 1036
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 1037 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQE 1094
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK 532
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L K
Sbjct: 1095 A------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLIK 1142
Query: 533 --LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
+++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +L
Sbjct: 1143 QEIEKEEENLQVVLRQMSKH-KTELKNILD-----MLQL-ENHELQGLKLQHDQRVS-EL 1194
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ Q+A EKL LE+ + ++++GE
Sbjct: 1195 EKTQVAVLEEKLE-LENLQQISQQQKGE 1221
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/272 (22%), Positives = 124/272 (45%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 1089 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 1147
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ +KN+ + L+ E K ++EL K +V +E L
Sbjct: 1148 EEENLQVVLRQMSKHKTE-LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 1206
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 1207 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 1266
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L VLA +E + ++E + R K +D N+ L +
Sbjct: 1267 WEKKL------AQTKRVLAAAEENSKMEQSNLEKLELNVR-KLQQELDQLNRDKLSLHND 1319
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 1320 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 1350
Score = 41.5 bits (93), Expect = 0.009
Identities = 38/178 (21%), Positives = 85/178 (47%), Gaps = 16/178 (8%)
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
++L+ + H K+ + +++ +N + L D + S++ +E +E+QL
Sbjct: 15 DSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLT 74
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL-----KCHYQKQLEDAVLAKLQEFQE 538
E Q +E LKK L+ + L+++L K + +C + ++ +L +L E ++
Sbjct: 75 EGQIAANEALKK--DLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQ 132
Query: 539 QLDRAE-REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL 595
+ D+ E M+ + KE ++S ++EQH E+N ++ + ++ Y +L
Sbjct: 133 ERDQLEIVAMDAENMRKELAELES------ALQEQH--EVNASLQQTQGDLSAYEAEL 182
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 1419 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 1478
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 1479 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 1532
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 1533 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 1590
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 1591 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 1649
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 1650 LPADLEAILERNENLEGE 1667
Score = 40.3 bits (90), Expect = 0.021
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 1131 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ-----LENHELQGLKL 1185
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 1186 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 1241
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETLLLT--- 458
++ L CV K E+ EK +K A E N +++ N E L L
Sbjct: 1242 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRK 1301
Query: 459 --QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 1302 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 1354
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 1355 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 1405
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 1406 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 1443
Score = 39.1 bits (87), Expect = 0.049
Identities = 72/350 (20%), Positives = 142/350 (40%), Gaps = 35/350 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
+DA ++L+E ++T + + LEK ++N A +++K SEL+
Sbjct: 189 RDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE-NSELHA 247
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN---------- 404
L QD L+ + K + LN +D + V +D L+
Sbjct: 248 KLK---HLQDDNNLLKQQLKDFQNHLNHVVDGL-VRPEEVAARVDELRRKLKLGTGEMNI 303
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER--- 461
+ L K L D K E L + K+ D + +L + + ++ E L QE
Sbjct: 304 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEM-ALQQEKLATGQEEFRQ 362
Query: 462 ---DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL- 517
L++++N ++ + QQ+ + + E LK + + Q + +K +
Sbjct: 363 ACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIL 422
Query: 518 ----KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +K+LEDA K QE LD+ ++++ + +++ H
Sbjct: 423 AQLRELEKKKKLEDA---KSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLH 479
Query: 574 KLEINVLEEKQRE--EIKLYRLQLAQAAEKLGLLESKVECQR---RRRGE 618
+ + +E+ E E + + + AQAA L E+++E + R++GE
Sbjct: 480 GTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGE 529
Score = 38.3 bits (85), Expect = 0.085
Identities = 54/266 (20%), Positives = 123/266 (46%), Gaps = 15/266 (5%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
H+ +++ +L++ + L+ + E + +KE++ L N D +++ K L V
Sbjct: 787 HNLENEVSRLEDIMQHLKSKKREERW-MRASKRQSEKEMEELHHNIDDLLQEKKSLECEV 845
Query: 420 KNLEEALEKEK----FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ L ++K + F + +S +TEL + E ++ E + ++ + + RS
Sbjct: 846 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIV--DEIECIEKTLLKRRSEL 903
Query: 476 AVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
++ L E +++ S +K + ++ R L+ + + + + Q L K
Sbjct: 904 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 963
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI-KLYR- 592
+ L +++E ++K+ I+ NK I+ ++ ++ +EK EE+ KL +
Sbjct: 964 QQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAAKDSDFQCLSKKKEKLTEELQKLQKD 1021
Query: 593 LQLAQAAE--KLGLL-ESKVECQRRR 615
+++A+ E L +L ES+V Q +R
Sbjct: 1022 IEMAERNEDHHLQVLKESEVLLQAKR 1047
Score = 38.3 bits (85), Expect = 0.085
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT----VMRLNKQLTDCVKN- 421
KQL K E++ E + + KE + L+E D + + + L +N
Sbjct: 1226 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 1285
Query: 422 -LEEA-LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+E++ LEK + + + +LN+ S++++ + Q+ + VN + A ++
Sbjct: 1286 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 1345
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK-CHYQKQLEDAVLAKLQ-EFQ 537
L + K D L +E L++ + N + C +++ + L LQ E +
Sbjct: 1346 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 1405
Query: 538 E-QLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
E +L ++EM KE +S ++ E+QH+LE + ++K + + L ++
Sbjct: 1406 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 1465
Query: 595 LAQ 597
A+
Sbjct: 1466 AAE 1468
Score = 35.1 bits (77), Expect = 0.80
Identities = 54/255 (21%), Positives = 113/255 (44%), Gaps = 27/255 (10%)
Query: 351 ELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMR 410
+L +D K ++ +K E+QL ++M +K+ L+ D ++
Sbjct: 9 DLQIAIDSLDSKDPKHSHMKAQKSGKEQQL-------DIM----NKQYQQLESRLDEILS 57
Query: 411 LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
+ T+ +K+LEE L + + A + L K ++ V L + +K + +
Sbjct: 58 RIAKETEEIKDLEEQLTEGQIAANEA------LKKDLEGVISG---LQEYLGTIKGQATQ 108
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
++ C + + + +EV ++ D L+ V +++ + EL+ Q+Q E V
Sbjct: 109 AQNECRKLRDEKETLLQRLTEVEQERDQLE-IVAMDAENMRKELAELESALQEQHE--VN 165
Query: 531 AKLQEFQEQLDRAEREMENDARLK--ENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
A LQ+ Q L E E+E L+ E N + +++ R+ + + + EK+R+ +
Sbjct: 166 ASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQAL 225
Query: 589 K--LYRLQLAQAAEK 601
K L + Q ++ E+
Sbjct: 226 KNALGKAQFSEEKEQ 240
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 53.6 bits (123), Expect = 2e-06
Identities = 80/328 (24%), Positives = 155/328 (47%), Gaps = 40/328 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 1459 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 1518
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
K ++ +D Q ++KK E+L EL + K+I++ + N D +++
Sbjct: 1519 LKEINKIVAAKDSDFQCLSKKK---EKLTEELQKLQ-------KDIEMAERNEDHHLQVL 1568
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 1569 KESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQE 1626
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAK 532
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L K
Sbjct: 1627 A------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLIK 1674
Query: 533 --LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
+++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +L
Sbjct: 1675 QEIEKEEENLQVVLRQMSKH-KTELKNILD-----MLQL-ENHELQGLKLQHDQRVS-EL 1726
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ Q+A EKL LE+ + ++++GE
Sbjct: 1727 EKTQVAVLEEKLE-LENLQQISQQQKGE 1753
Score = 47.6 bits (108), Expect = 1e-04
Identities = 59/279 (21%), Positives = 129/279 (46%), Gaps = 32/279 (11%)
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL------DNVNVMLS 392
+D +KK S ++ L + D + + + E K LEE + + D + LS
Sbjct: 440 EDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLS 499
Query: 393 NKDKEIDVLK-ENYDTVMRLNKQLTDC------VKNLE---EALEKEKFAHDSTKSNITE 442
+ + ++ L+ E D +++ KQ + +K+L+ ++L+ + H K+ +
Sbjct: 500 GRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSG 559
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
+++ +N + L D + S++ +E +E+QL E Q +E LKK L+
Sbjct: 560 KEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK--DLEGV 617
Query: 503 VKTLRQHLELQKNEL-----KCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKEN 556
+ L+++L K + +C + ++ +L +L E +++ D+ E M+ + KE
Sbjct: 618 ISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKEL 677
Query: 557 NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL 595
++S ++EQH E+N ++ + ++ Y +L
Sbjct: 678 AELES------ALQEQH--EVNASLQQTQGDLSAYEAEL 708
Score = 47.6 bits (108), Expect = 1e-04
Identities = 62/272 (22%), Positives = 124/272 (45%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 1621 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 1679
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ +KN+ + L+ E K ++EL K +V +E L
Sbjct: 1680 EEENLQVVLRQMSKHKTE-LKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 1738
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 1739 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 1798
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L VLA +E + ++E + R K +D N+ L +
Sbjct: 1799 WEKKL------AQTKRVLAAAEENSKMEQSNLEKLELNVR-KLQQELDQLNRDKLSLHND 1851
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 1852 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 1882
Score = 43.6 bits (98), Expect = 0.002
Identities = 63/285 (22%), Positives = 130/285 (45%), Gaps = 31/285 (10%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNV------NVMLSNKDKEIDV----LKENYDTVMRLNK 413
D + +Q +K +EQL + N+ + L +K+K+I L E +D + + +
Sbjct: 406 DSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQ 465
Query: 414 QL---TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
Q+ T+ K LEEA++ +K + +L+ R+Q VN L QE L+ ++ +
Sbjct: 466 QILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNK----LRQEALDLELQMEK 521
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE---D 527
++ A ++++ + Q + K D + +K + E Q + + YQ QLE D
Sbjct: 522 QKQEIAGKQKEIKDLQIAIDSLDSK-DPKHSHMKAQKSGKEQQLDIMNKQYQ-QLESRLD 579
Query: 528 AVLAKLQEFQEQLDRAEREM------ENDARLKE-NNIVDSFNKQILRIEEQHKLEINVL 580
+L+++ + E++ E ++ N+A K+ ++ + + I+ Q N
Sbjct: 580 EILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNEC 639
Query: 581 EE-KQREEIKLYRL-QLAQAAEKLGLLESKVECQRRRRGETAARL 623
+ + +E L RL ++ Q ++L ++ E R+ E + L
Sbjct: 640 RKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESAL 684
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 1951 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 2010
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 2011 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 2064
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 2065 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 2122
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 2123 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 2181
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 2182 LPADLEAILERNENLEGE 2199
Score = 40.3 bits (90), Expect = 0.021
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 1663 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQ-----LENHELQGLKL 1717
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 1718 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 1773
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETLLLT--- 458
++ L CV K E+ EK +K A E N +++ N E L L
Sbjct: 1774 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRK 1833
Query: 459 --QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 1834 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 1886
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 1887 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 1937
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 1938 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 1975
Score = 39.1 bits (87), Expect = 0.049
Identities = 72/350 (20%), Positives = 142/350 (40%), Gaps = 35/350 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
+DA ++L+E ++T + + LEK ++N A +++K SEL+
Sbjct: 715 RDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE-NSELHA 773
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN---------- 404
L QD L+ + K + LN +D + V +D L+
Sbjct: 774 KLK---HLQDDNNLLKQQLKDFQNHLNHVVDGL-VRPEEVAARVDELRRKLKLGTGEMNI 829
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER--- 461
+ L K L D K E L + K+ D + +L + + ++ E L QE
Sbjct: 830 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEM-ALQQEKLATGQEEFRQ 888
Query: 462 ---DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL- 517
L++++N ++ + QQ+ + + E LK + + Q + +K +
Sbjct: 889 ACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIL 948
Query: 518 ----KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +K+LEDA K QE LD+ ++++ + +++ H
Sbjct: 949 AQLRELEKKKKLEDA---KSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLH 1005
Query: 574 KLEINVLEEKQRE--EIKLYRLQLAQAAEKLGLLESKVECQR---RRRGE 618
+ + +E+ E E + + + AQAA L E+++E + R++GE
Sbjct: 1006 GTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGE 1055
Score = 38.3 bits (85), Expect = 0.085
Identities = 54/266 (20%), Positives = 123/266 (46%), Gaps = 15/266 (5%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
H+ +++ +L++ + L+ + E + +KE++ L N D +++ K L V
Sbjct: 1319 HNLENEVSRLEDIMQHLKSKKREERW-MRASKRQSEKEMEELHHNIDDLLQEKKSLECEV 1377
Query: 420 KNLEEALEKEK----FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ L ++K + F + +S +TEL + E ++ E + ++ + + RS
Sbjct: 1378 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIV--DEIECIEKTLLKRRSEL 1435
Query: 476 AVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
++ L E +++ S +K + ++ R L+ + + + + Q L K
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI-KLYR- 592
+ L +++E ++K+ I+ NK I+ ++ ++ +EK EE+ KL +
Sbjct: 1496 QQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAAKDSDFQCLSKKKEKLTEELQKLQKD 1553
Query: 593 LQLAQAAE--KLGLL-ESKVECQRRR 615
+++A+ E L +L ES+V Q +R
Sbjct: 1554 IEMAERNEDHHLQVLKESEVLLQAKR 1579
Score = 38.3 bits (85), Expect = 0.085
Identities = 51/243 (20%), Positives = 106/243 (43%), Gaps = 12/243 (4%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT----VMRLNKQLTDCVKN- 421
KQL K E++ E + + KE + L+E D + + + L +N
Sbjct: 1758 KQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS 1817
Query: 422 -LEEA-LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+E++ LEK + + + +LN+ S++++ + Q+ + VN + A ++
Sbjct: 1818 KMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQ 1877
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK-CHYQKQLEDAVLAKLQ-EFQ 537
L + K D L +E L++ + N + C +++ + L LQ E +
Sbjct: 1878 DHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIE 1937
Query: 538 E-QLDRAEREMENDARLKENNIVDS--FNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
E +L ++EM KE +S ++ E+QH+LE + ++K + + L ++
Sbjct: 1938 ENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVL 1997
Query: 595 LAQ 597
A+
Sbjct: 1998 AAE 2000
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated
protein CEP110 protein.
Length = 994
Score = 53.6 bits (123), Expect = 2e-06
Identities = 82/329 (24%), Positives = 156/329 (47%), Gaps = 42/329 (12%)
Query: 298 AISKLREAWLRLTNSLDRAEDRHRKALEKMICEV---ENFRVVADDAQKKTSHF--ESEL 352
A+ K +A L + AE+ R+A E + V + R + DA+ H + E+
Sbjct: 128 AVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI 187
Query: 353 YKTLDLAHDYQDKCKQ-LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRL 411
K ++ +D Q L +K+ L E+L ++ + N+D + VLKE+ + +++
Sbjct: 188 LKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKES-EVLLQ- 245
Query: 412 NKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEE 471
K E LEK K S + + L++++ +E LL + ++++K + +
Sbjct: 246 -------AKRAE--LEKLKSQVTSQQQEMAVLDRQLGHKKEELHLL--QGSMVQAKADLQ 294
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLA 531
+ +L E +EV +KC+ + EVK+L + L QK EL ++ L
Sbjct: 295 EA------LRLGE-----TEVTEKCNHI-REVKSLLEELSFQKGELNVQISERKTQLTLI 342
Query: 532 K--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
K +++ +E L R+M + + NI+D +L++ E H+L+ L+ QR +
Sbjct: 343 KQEIEKEEENLQVVLRQMSKH-KTELQNILD-----MLQL-ENHELQGLKLQHDQRVS-E 394
Query: 590 LYRLQLAQAAEKLGLLESKVECQRRRRGE 618
L + Q+A EKL LE+ + ++++GE
Sbjct: 395 LEKTQVAVLEEKLE-LENLQQISQQQKGE 422
Score = 45.6 bits (103), Expect = 6e-04
Identities = 59/272 (21%), Positives = 126/272 (46%), Gaps = 26/272 (9%)
Query: 349 ESELYKTLDLAH-DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLK----- 402
+++L + L L + +KC ++ E KSL E+L+ + +NV +S + ++ ++K
Sbjct: 290 KADLQEALRLGETEVTEKCNHIR-EVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEK 348
Query: 403 --ENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTK----SNITELNKRIQSVNDETL 455
EN V+R ++K T+ ++N+ + L+ E K ++EL K +V +E L
Sbjct: 349 EEENLQVVLRQMSKHKTE-LQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL 407
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE--VLKKC-DFLDNEVKTLRQHLEL 512
L + + + + E + ++E+ E + +E L+ C + L E + L++ ++
Sbjct: 408 ELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDI 467
Query: 513 QKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQ 572
+ +L Q + + A + + + E+ N +L++ +D N+ L +
Sbjct: 468 WEKKL-----AQTKRVLAAAEENSKMEQSNLEKLDLNVRKLQQE--LDQLNRDKLSLHND 520
Query: 573 HKLEINVLEEKQREEIKLYRLQLAQAAEKLGL 604
L+EK RE + + +LA + L L
Sbjct: 521 ISAMQQQLQEK-REAVNSLQEELANVQDHLNL 551
Score = 41.1 bits (92), Expect = 0.012
Identities = 57/258 (22%), Positives = 110/258 (42%), Gaps = 15/258 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA- 425
++LQ E++S E +L T + +KE+ K D V+ + V+ L+E
Sbjct: 620 QRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEE 679
Query: 426 --LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
E + TK ++E +++ + E L L +E D +++ + R+ Q L
Sbjct: 680 RWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRN------QFLT 733
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRA 543
E++ +V + L + L ++L QK E C QK++ L Q+ E+ R
Sbjct: 734 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSC-IQKEMATIELV-AQDNHERARRL 791
Query: 544 EREMENDARLKENNIVDSF--NKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK 601
+E+ N + + + K + R + + + L+ + ++EI+ L Q +
Sbjct: 792 MKEL-NQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPE 850
Query: 602 LGL-LESKVECQRRRRGE 618
L LE+ +E GE
Sbjct: 851 LPADLEAILERNENLEGE 868
Score = 39.9 bits (89), Expect = 0.028
Identities = 78/339 (23%), Positives = 148/339 (43%), Gaps = 48/339 (14%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
IS+ + + +++ E+ + L +M + + D Q E+ + L L
Sbjct: 332 ISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNILDMLQ-----LENHELQGLKL 386
Query: 359 AHDYQDKCKQLQNEKKS-LEEQLNTELDNVNVMLSNKDKEID----VLKENYDTVMRL-- 411
HD + +L+ + + LEE+L EL+N+ + + EI+ +L+ + + R+
Sbjct: 387 QHD--QRVSELEKTQVAVLEEKL--ELENLQQISQQQKGEIEWQKQLLERDKREIERMTA 442
Query: 412 -NKQLTDCV----KNLEEALEK-----EKFAHDSTKSNITELNKRIQSVNDETL-----L 456
++ L CV K E+ EK +K A E N +++ N E L
Sbjct: 443 ESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLDLNVRK 502
Query: 457 LTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
L QE D L + + ++QQL EK+ + L E+ ++ HL L K +
Sbjct: 503 LQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNS-------LQEELANVQDHLNLAKQD 555
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
L H K +D +L++ Q+ + E+ + +E +Q L++ Q+++E
Sbjct: 556 L-LHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKEEET------KQQQLQV-LQNEIE 606
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRR 615
N L+ Q +E+ RLQ + +E+ L SKV + ++
Sbjct: 607 ENKLKLVQ-QEMMFQRLQKERESEESKLETSKVTLKEQQ 644
Score = 37.1 bits (82), Expect = 0.20
Identities = 50/231 (21%), Positives = 108/231 (46%), Gaps = 14/231 (6%)
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK----FAHDSTKSNITELNKRIQSV 450
+KE++ L N D +++ K L V+ L ++K + F + +S +TEL
Sbjct: 22 EKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQRQKDFIDGNVESLMTELEIEKSLK 81
Query: 451 NDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQH 509
+ E ++ E + ++ + + RS ++ L E +++ S +K + ++ R
Sbjct: 82 HHEDIV--DEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSL 139
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
L+ + + + + Q L K + L +++E ++K+ I+ NK I+
Sbjct: 140 LQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAA 197
Query: 570 EEQHKLEINVLEEKQREEI-KLYR-LQLAQAAE--KLGLL-ESKVECQRRR 615
++ ++ +EK EE+ KL + +++A+ E L +L ES+V Q +R
Sbjct: 198 KDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKR 248
>AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled coil
protein protein.
Length = 1594
Score = 53.6 bits (123), Expect = 2e-06
Identities = 60/269 (22%), Positives = 121/269 (44%), Gaps = 24/269 (8%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDN-VNVMLSNKDKEIDV 400
+++T + +E+ K L QD + Q L + E D ++ ++S ++E ++
Sbjct: 1094 EQETENLRTEISK---LNQKIQDNNENYQVGLAELRTLMTIEKDQRISELISRHEEESNI 1150
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNI-TELNKRI--QSVNDETLLL 457
LK + V L+ Q + KNL+E + + + DS S + + +++I Q E ++
Sbjct: 1151 LKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQ 1210
Query: 458 TQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC----DFLDNEVKTLRQHLELQ 513
E+D K ++E+ R +I++ CEK LK+ + ++ E+ +HLE Q
Sbjct: 1211 NLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQ 1270
Query: 514 -------------KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+ L Q++L++ L++ +EQ R EM+N
Sbjct: 1271 IAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAEQQT 1330
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
+FN + R + + + IN L +K + ++
Sbjct: 1331 NFNTVLTREKMRKENIINDLSDKLKSTMQ 1359
Score = 41.5 bits (93), Expect = 0.009
Identities = 62/267 (23%), Positives = 118/267 (44%), Gaps = 26/267 (9%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLE---EQLNTELDNVNVMLSNKDKEIDVLKENY 405
E + L L ++Y+ K L E + E ++L EL + +L NKD E ++K
Sbjct: 861 EKHQKELLSLKNEYEGKLDGLIKETEENENKIKKLKGELVCLEEVLQNKDNEFALVKHEK 920
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
+ V+ L + ++ LE E H S I EL + + V ++ L E D
Sbjct: 921 EAVICLQNEKD------QKLLEMENIMH-SQNCEIKELKQSREIVLEDLKKLHVEND--- 970
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+ R+ +EQ ++ +V +F K + H + ELK Q+
Sbjct: 971 EKLQLLRAELQSLEQSHLKELEDTLQVRHIQEF----EKVMTDH-RVSLEELKKENQQ-- 1023
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK-QI-LRIEEQHKLEINV-LEE 582
++ ++QE ++ + + + + +LK +++ D+ K ++ L ++E EI + LEE
Sbjct: 1024 ---IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEE 1080
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKV 609
+ ++ + + L Q E L SK+
Sbjct: 1081 SRAQQKETLKSLLEQETENLRTEISKL 1107
Score = 32.3 bits (70), Expect = 5.6
Identities = 38/195 (19%), Positives = 87/195 (44%), Gaps = 14/195 (7%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRH-RKALEKMICEVENFRVVADDAQKK 344
A+ +++ + +S + +L L+ +D + AL++ E E VV + +K
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLERE---VVEKELLEK 1263
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
H E+++ K+ + D + ++ L+E+ L+ + K++E+ +N
Sbjct: 1264 VKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEM----QN 1319
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAH---DSTKSNITELNK---RIQSVNDETLLLT 458
T + +Q E + KE + D KS + + + I+S++++ L
Sbjct: 1320 VRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLL 1379
Query: 459 QERDLLKSKVNEERS 473
+E+ L+ +V++ RS
Sbjct: 1380 EEKKKLEEEVSKLRS 1394
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 51.6 bits (118), Expect = 9e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAK 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 39.9 bits (89), Expect = 0.028
Identities = 40/260 (15%), Positives = 110/260 (42%), Gaps = 9/260 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE---- 397
+K+ + F+ + ++ L+ + +L ++DN+ + +KE
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1224
Query: 398 ---IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+D + N + +++ L + LE+ + + + + T+ ++ +L + + E
Sbjct: 1225 KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Query: 455 LLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
L+++ D ++ +++ QQL + + Q E +K + L + +++ R +L +
Sbjct: 1285 GELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
+ + + + E + L + ++ + + E DA + + ++ K R++E +
Sbjct: 1345 EQYEEETEAKAE--LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 575 LEINVLEEKQREEIKLYRLQ 594
V + E +RLQ
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQ 1422
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 51.6 bits (118), Expect = 9e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAK 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 39.9 bits (89), Expect = 0.028
Identities = 40/260 (15%), Positives = 110/260 (42%), Gaps = 9/260 (3%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKE---- 397
+K+ + F+ + ++ L+ + +L ++DN+ + +KE
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1224
Query: 398 ---IDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
+D + N + +++ L + LE+ + + + + T+ ++ +L + + E
Sbjct: 1225 KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Query: 455 LLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
L+++ D ++ +++ QQL + + Q E +K + L + +++ R +L +
Sbjct: 1285 GELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
+ + + + E + L + ++ + + E DA + + ++ K R++E +
Sbjct: 1345 EQYEEETEAKAE--LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 575 LEINVLEEKQREEIKLYRLQ 594
V + E +RLQ
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQ 1422
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 30 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 89
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 90 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 138
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 139 SLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 198
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 199 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 254
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 255 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 308
Score = 43.2 bits (97), Expect = 0.003
Identities = 51/274 (18%), Positives = 118/274 (43%), Gaps = 26/274 (9%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
+++A+ H + ++ + ++ ++A + E +L + + L+H + + Q
Sbjct: 172 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR-MAAEAQK 230
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ KSL+ L + + L + + D LKEN V R N L ++ L +E+ +
Sbjct: 231 QVKSLQSLLK----DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 286
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + E ++R+Q LL +Q L+ K ++ L + Q + E
Sbjct: 287 SRKLAEQELIETSERVQ------LLHSQNTSLINQKKK--------MDADLSQLQTEVEE 332
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDA 551
+++C + + K + ELK E A L+ ++ +++ +++++
Sbjct: 333 AVQECRNAEEKAKKAITDAAMMAEELK------KEQDTSAHLERMKKNMEQTIKDLQHRL 386
Query: 552 RLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
E + KQ+ ++E + + N LE +Q+
Sbjct: 387 DEAEQIALKGGKKQLQKLEARVRELENELEAEQK 420
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1122 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 1179 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 1239 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 1298
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 1356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1417 TKHRLQ 1422
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 908 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 965
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 966 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1020
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1021 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1080
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1081 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1140
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1141 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1197
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1198 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1234
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 59 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 118
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 119 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 174
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 175 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 231
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 232 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 291
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 292 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 351
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 352 RDEGLLLAESEKQQA---LSLKESE 373
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 1486 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 1543
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 1544 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1598
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1599 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1658
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1659 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1718
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1719 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1775
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1776 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1812
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/290 (23%), Positives = 118/290 (40%), Gaps = 20/290 (6%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN---LEEA 425
L EK +L L + ++K +E RL ++ D V++ +
Sbjct: 482 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE 541
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
LE+ + + + L K + V + T +RD+L+++ E E E
Sbjct: 542 LERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 601
Query: 486 QNQCSEV-LKKCDFLDN--EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ +++ ++ D+ ++ L + L K +L QLE+ A LQ Q Q ++
Sbjct: 602 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-RLVAQLEEEKSA-LQGRQRQAEQ 659
Query: 543 -AEREMENDARLKENNIVDSFNKQ----ILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
A E RL+E + +Q LR+ EQ + + R E + QLAQ
Sbjct: 660 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 719
Query: 598 AAEKLGLLESKVECQRRRRG------ETAARLHAAL-QAHWRHALRILAA 640
+ +L E ++E RR E AAR AL + H A++++AA
Sbjct: 720 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 769
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 637 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 696
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 697 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 752
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 753 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 809
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 810 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 869
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 870 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 929
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 930 RDEGLLLAESEKQQA---LSLKESE 951
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 1605 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 1662
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 1663 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1717
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1718 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1777
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1778 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1837
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1838 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1894
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1895 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1931
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/290 (23%), Positives = 118/290 (40%), Gaps = 20/290 (6%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN---LEEA 425
L EK +L L + ++K +E RL ++ D V++ +
Sbjct: 601 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE 660
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
LE+ + + + L K + V + T +RD+L+++ E E E
Sbjct: 661 LERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 720
Query: 486 QNQCSEV-LKKCDFLDN--EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ +++ ++ D+ ++ L + L K +L QLE+ A LQ Q Q ++
Sbjct: 721 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-RLVAQLEEEKSA-LQGRQRQAEQ 778
Query: 543 -AEREMENDARLKENNIVDSFNKQ----ILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
A E RL+E + +Q LR+ EQ + + R E + QLAQ
Sbjct: 779 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 838
Query: 598 AAEKLGLLESKVECQRRRRG------ETAARLHAAL-QAHWRHALRILAA 640
+ +L E ++E RR E AAR AL + H A++++AA
Sbjct: 839 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 888
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 756 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 815
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 871
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 872 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 929 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 988
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 989 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 1048
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 1049 RDEGLLLAESEKQQA---LSLKESE 1070
Score = 31.9 bits (69), Expect = 7.4
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 17/193 (8%)
Query: 375 SLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
SL+E+ L EL V +L+ E D L Y+ V +Q E E
Sbjct: 78 SLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGL 137
Query: 432 AHDSTK------SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
S + +++Q+ + Q L+ K+ + + RC+ +EQQL E+
Sbjct: 138 VRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLER 197
Query: 486 QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA-VLAKLQEFQEQLDRAE 544
+ L++ D E Q LE L+ Q+ A V A L+E +Q A
Sbjct: 198 SGE----LEQQRLRDTEHS---QDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSAN 250
Query: 545 REMENDARLKENN 557
+ + D R N+
Sbjct: 251 QALSEDIRKVTND 263
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1122 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 1179 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 1239 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 1298
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 1356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1417 TKHRLQ 1422
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 1122 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 1179 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 1239 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 1298
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 1356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1417 TKHRLQ 1422
>BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein.
Length = 613
Score = 53.2 bits (122), Expect = 3e-06
Identities = 65/275 (23%), Positives = 120/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 132 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 191
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 192 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 251
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E+ + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 252 EILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFI 311
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 312 LEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELD 371
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 372 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 406
Score = 50.4 bits (115), Expect = 2e-05
Identities = 68/315 (21%), Positives = 132/315 (41%), Gaps = 20/315 (6%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N + Q++ + + + L ++ L + S +
Sbjct: 290 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 349
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN-------LEE------ 424
E++ E + L E+D L++ + RL KQL + K+ LEE
Sbjct: 350 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKE 409
Query: 425 -ALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
LEK AH + E + +QS+ D T + L S++ + + + ++++
Sbjct: 410 AELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA 469
Query: 483 CEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQ-KNELKCHYQKQLEDAVLAKLQEFQEQL 540
+ +V + + + + +R L+LQ K+ LK K++ + L K+ + Q QL
Sbjct: 470 AKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQL 529
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL-AQAA 599
+ E + +E + N EE +K + L E+ + K ++LQL A
Sbjct: 530 KQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRL--LYEELYNKTKPFQLQLDAFEV 587
Query: 600 EKLGLLESKVECQRR 614
EK LL Q +
Sbjct: 588 EKQALLNEHGAAQEQ 602
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/275 (21%), Positives = 126/275 (45%), Gaps = 21/275 (7%)
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLE 423
K ++ + +K+S ++ LN + D + K K E+ V+ + D +++LE
Sbjct: 40 KSQRFKQQKES-KQNLNVDKDTTLPASARKVKS----SESKIRVLLQERGAQDRRIQDLE 94
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE--ERSRCAVIEQQ 481
LEK + ++ T L+ ++ + + LT+ +LLKSK +E + ++ +
Sbjct: 95 TELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLE 154
Query: 482 LCEKQN----QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
L + +N + ++ K + ++ +++ ++ LE + ++ QLE +++ +E
Sbjct: 155 LMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-----AQLEGKLVSIEKEKI 209
Query: 538 EQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKL---EINVLEEKQREEIKLYRL 593
++ E+ +E + ++ V+ + I ++EE K EI L++ E I +
Sbjct: 210 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSK 269
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
Q+ K LLE + E R E L+A +Q
Sbjct: 270 QVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQ 304
Score = 37.5 bits (83), Expect = 0.15
Identities = 60/281 (21%), Positives = 117/281 (41%), Gaps = 22/281 (7%)
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-------KSLEEQLNTEL 384
EN + D+ E + D KC+ L+ EK + E LN E+
Sbjct: 244 ENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEM 303
Query: 385 DNV--NVMLSNKDKEIDVLKE-NYDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDST 436
N+ +L +++E KE D++++ K+L+ + + +E + KEK +
Sbjct: 304 QNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEEL 363
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC 496
K + EL+K Q L+ Q + KS+ E + ++ + E + + +
Sbjct: 364 KQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQAT 423
Query: 497 DFLDNEVKTLRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
L + ++ Q LE Q K ++ED L QE+ +A + E D +
Sbjct: 424 LLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN-SSLQEKAAKAGKNAE-DVQ- 480
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
+ +S N++ +R+ + + + L+E + +EI + LQ
Sbjct: 481 HQILATESSNQEYVRMLLDLQTK-SALKETEIKEITVSFLQ 520
>AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A
protein.
Length = 1016
Score = 53.2 bits (122), Expect = 3e-06
Identities = 78/336 (23%), Positives = 151/336 (44%), Gaps = 43/336 (12%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E L +++ L A ++ +A+ + ++E+ +V + +++ + E ++L Q
Sbjct: 198 ELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC----Q 253
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
++ ++ +E+ EQL EL S + ID + R ++ TD + LE
Sbjct: 254 EELRERLHEESRAREQLAVEL-------SKAEGVIDGYADEKTLFERQIQEKTDIIDRLE 306
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ L SN R+Q + E + +ER+LL + ++ +EQQL
Sbjct: 307 QEL--------LCASN------RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 352
Query: 484 -EKQNQCSEVLK-KC------DFLDNEVKTLRQHLELQKN---ELKCHYQKQLEDAVLAK 532
E + E L+ +C D L +VK L +E Q + EL+ +L D + +
Sbjct: 353 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMD-LRQQ 411
Query: 533 LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLEEKQREEIKL 590
Q ++QL++ + ++ A +E+ D F ++I ++E+Q K+ + E Q E++
Sbjct: 412 NQALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQ 470
Query: 591 YRLQLAQAAEKLG-LLESKVECQR--RRRGETAARL 623
L + +K LL SK + QR + R E +L
Sbjct: 471 LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL 506
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/367 (20%), Positives = 156/367 (42%), Gaps = 23/367 (6%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L EE RE + + + + K I +L + L +N L
Sbjct: 259 RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQE 318
Query: 316 AEDRHRKALEK---MICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
E ++ E+ + + E + A +++ +L K L++ + LQ
Sbjct: 319 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 378
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ K+LE + ++ + K+ E+ L++ L KQL K L+E +
Sbjct: 379 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQA---LEKQLEKMRKFLDEQAIDREH 435
Query: 432 AHDSTKSNITELNKRIQSVNDETLLL---TQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
D + I +L ++++ V + T+E + L + + E+ +C+ + + Q
Sbjct: 436 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 495
Query: 489 CSEVLKKCDFLDNEVKTLRQHL-----ELQKNELKCHY---QKQLEDAVLAKLQEFQEQL 540
E ++ + L+ V+ L Q L QK E + H+ + + E ++ +LQ ++ +
Sbjct: 496 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 555
Query: 541 DRAEREMEN-DARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
DR E+E+ N + +L++ +++ N+++ ++ Q LEI E R +E++
Sbjct: 556 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ--LEIQKKESTTRLQELEQENKLFKD 613
Query: 598 AAEKLGL 604
EKLGL
Sbjct: 614 DMEKLGL 620
Score = 44.0 bits (99), Expect = 0.002
Identities = 76/344 (22%), Positives = 147/344 (42%), Gaps = 30/344 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A K+ A S+L A + T + + + ++A E + C+ E R + +
Sbjct: 209 AAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQ-EELRERLHEESRAR 267
Query: 346 SHFESELYKTLDLAHDYQDKC----KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
EL K + Y D+ +Q+Q EK + ++L EL + L + E +
Sbjct: 268 EQLAVELSKAEGVIDGYADEKTLFERQIQ-EKTDIIDRLEQELLCASNRLQELEAEQQQI 326
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+E + + R + + +E+ L +E + E+ + + V D+ L ++
Sbjct: 327 QEERELLSRQKEAMKAEAGPVEQQLLQET---EKLMKEKLEVQCQAEKVRDD---LQKQV 380
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ---KNELK 518
L+ V E+ SR +EQ EK + ++ ++ L+ +++ +R+ L+ Q + +
Sbjct: 381 KALEIDVEEQVSRFIELEQ---EKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER 437
Query: 519 CHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDAR-LKENNIVDS---FNKQIL----- 567
+Q++++ + L + FQ + RE+E A LKE S +K+ L
Sbjct: 438 DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 497
Query: 568 -RIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
R EE KLE V E +Q + Q + + G +E+K E
Sbjct: 498 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 541
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 8/209 (3%)
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
TEL V EID EN + ++ ++ +L V+ L EA+ + + K T
Sbjct: 176 TELSQRLVRSGFAGTEID--PENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQT 233
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
EL + E + ++ L+ +++EE + +L + + + +
Sbjct: 234 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 293
Query: 502 EVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+++ ++ + EL C + E +A ++QE +E L R + M+ +A E ++
Sbjct: 294 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 353
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
K + + KLE+ EK R++++
Sbjct: 354 ETEKLM-----KEKLEVQCQAEKVRDDLQ 377
Score = 37.9 bits (84), Expect = 0.11
Identities = 51/265 (19%), Positives = 108/265 (40%), Gaps = 24/265 (9%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNV 389
++ V D ++ + + +L T D +K + +NE + LE Q+ + +
Sbjct: 644 IQEKEVEIDQLNEQVTKLQQQLKITTD------NKVIEEKNELIRDLETQIECLMSDQEC 697
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
+ N+++EI+ L E + +L ++L + + DS K + + +
Sbjct: 698 VKRNREEEIEQLNE---VIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 754
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + +E +K+ + E + + Q+L + + V K +N V H
Sbjct: 755 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 814
Query: 510 LELQKNELKC----HYQKQLEDAVLAKLQEFQE-------QLDRAEREMENDARLKENNI 558
L K EL+ K LE+ + F+E L+ ++E+ K+ +
Sbjct: 815 LSKDKPELEVVLTEDALKSLENQTY--FRSFEENGKGSIINLETRLLQLESTVSAKDLEL 872
Query: 559 VDSFNKQILRIEEQHKLEINVLEEK 583
+ KQI ++EQ + E +L++K
Sbjct: 873 TQCY-KQIKDMQEQGQFETEMLQKK 896
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 685 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 744
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 745 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 793
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 794 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 853
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 854 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 909
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 910 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 963
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 85 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 144
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 145 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 200
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 201 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 260
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 261 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 320
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 321 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 375
Score = 44.0 bits (99), Expect = 0.002
Identities = 69/355 (19%), Positives = 152/355 (42%), Gaps = 33/355 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 229 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 288
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 289 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 348
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 349 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 408
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 409 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 467
Query: 517 LKCHYQ---KQLEDAVLAK--LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
K +E + AK L++ L+ E + A + ++ D ++Q E
Sbjct: 468 FKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTE 527
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+L L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 528 NGELS-RQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 580
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 772 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 831
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 832 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 891
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 892 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 950
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 951 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1010
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1011 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1064
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1065 ELENELEAEQK 1075
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 366 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 422
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 423 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 482
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 483 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALI 542
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 543 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 600
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 601 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 660
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 661 TKHRLQ 666
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 53.2 bits (122), Expect = 3e-06
Identities = 64/295 (21%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEID 399
D+ KTS E +L D QDKC +++ E +L+ + V +LS K+ E+
Sbjct: 439 DSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEM----TRLHRRVSEVEAVLSQKEVELK 494
Query: 400 VLKENYDTVMR-LNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLT 458
+ + + L +T+C +L+ +LE+ + E +K +Q ++D +
Sbjct: 495 ASETQRSLLEQDLATYITEC-SSLKRSLEQARMEVSQ------EDDKALQLLHD---IRE 544
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL 517
Q R L + K E +++ + + + + ++ D ++E++ R E ++
Sbjct: 545 QSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKAT 604
Query: 518 KCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN-DARLKENNIVDSFNKQILRIEEQHKLE 576
+C ++ + AK Q E + A+ E N + +LK + + K + E +L
Sbjct: 605 ECQHK-----LLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELL 659
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA-LQAH 630
N+ + K+R E +L +LQ + + + G+ + VE + A++ A L+ H
Sbjct: 660 QNIRQAKERAERELEKLQNREDSSE-GIRKKLVEAEELEEKHREAQVSAQHLEVH 713
Score = 52.4 bits (120), Expect = 5e-06
Identities = 75/308 (24%), Positives = 142/308 (46%), Gaps = 26/308 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKTLDLAHDY-QDKCKQLQN 371
A D ++LE+ I E+ +A ++ ++ + E+ L Y + + +L+
Sbjct: 769 AMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEA 828
Query: 372 EKKSLEEQL----NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE--- 424
+ + LEEQL + + + N +L + + +V E+ + + L +QLT+ +L+E
Sbjct: 829 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERES 888
Query: 425 ---ALEKEKFAHDST-KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
AL+ + A +S + TEL + +E LT RD ++ K + R+ C VI
Sbjct: 889 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI-T 947
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQ 539
L E+ NQ +E + L+N+ L + L+ Q + E D + ++ E + Q
Sbjct: 948 DLEEQLNQLTEDNAE---LNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 1004
Query: 540 LDRAEREME---NDARLKENNIVD--SFNKQILRIEEQHKLEINVL-EEKQREEIKLYRL 593
L ++ ME + E ++D + N ++L E Q + +VL +EK + E ++ L
Sbjct: 1005 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 1064
Query: 594 QLAQAAEK 601
Q EK
Sbjct: 1065 QRMLDTEK 1072
Score = 49.6 bits (113), Expect = 3e-05
Identities = 65/328 (19%), Positives = 142/328 (43%), Gaps = 21/328 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
M+V + D A+ L + + + E ++ +E+M + A++++ +
Sbjct: 526 MEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLY 585
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL-DNVNVMLSNKDKEIDV--LKENY 405
ESEL ++ A +++ K + Q++ ++Q E+ + + N ++++ + L+E
Sbjct: 586 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 645
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
+ ++ + + T+ ++N+ +A E+ + + +L R S L E + L+
Sbjct: 646 EKAVKASTEATELLQNIRQAKER-------AERELEKLQNREDSSEGIRKKLV-EAEELE 697
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K E + +E L +K+ E +K LDN++K E +N ++ H ++
Sbjct: 698 EKHREAQVSAQHLEVHLKQKEQHYEEKIK---VLDNQIKKDLADKETLENMMQRHEEEAH 754
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV-LEEKQ 584
E K+ Q+ + A M++ R E IV+ L + N+ +E+
Sbjct: 755 EK---GKILSEQKAMINA---MDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 808
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQ 612
E++ + L A KL K+E Q
Sbjct: 809 ISELRQQKFYLETQAGKLEAQNRKLEEQ 836
Score = 49.2 bits (112), Expect = 5e-05
Identities = 81/343 (23%), Positives = 152/343 (44%), Gaps = 45/343 (13%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRK---ALEKM----------ICEVE-NFRVVA 338
+A++ IS+LR+ L + E ++RK LEK+ + E+E R V+
Sbjct: 803 KAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVS 862
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
+ +++ + +L + + + + LQ + +LE QL + + ++EI
Sbjct: 863 LEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEI 922
Query: 399 DVLKENYDTVMRLNKQL-TDC--VKNLEEALEKEKFAHDSTKSNITELNKRI---QSVND 452
L + D + R L C + +LEE L + + + L+K++ ND
Sbjct: 923 QALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND 982
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQ-HL 510
E + L E D L+ ++ E E QL Q Q E LK C L+ +V L +
Sbjct: 983 EIVQLRSEVDHLRREITER-------EMQL-TSQKQTMEALKTTCTMLEEQVMDLEALND 1034
Query: 511 ELQKNELKCHYQKQL----EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
EL + E + + + + +++E Q LD E ++ AR + I +S +Q+
Sbjct: 1035 ELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLD---TEKQSRAR-ADQRITES--RQV 1088
Query: 567 LRIE-EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+ + ++HK EI L++ +E+ +L+ ++KL LE K
Sbjct: 1089 VELAVKEHKAEILALQQALKEQ----KLKAESLSDKLNDLEKK 1127
Score = 37.1 bits (82), Expect = 0.20
Identities = 76/328 (23%), Positives = 136/328 (41%), Gaps = 43/328 (13%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKA-LEKMICEVENFRVVADDAQKKTSHFESELYKTLD 357
I+ L E +LT D AE ++ L K + E + + H E+ +
Sbjct: 946 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 1003
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+ + L+ LEEQ+ +L+ +N L K+++ E + +V+ K +
Sbjct: 1004 QLTSQKQTMEALKTTCTMLEEQV-MDLEALNDELLEKERQW----EAWRSVLGDEKSQFE 1058
Query: 418 C-VKNLEEALEKEKFAHDSTKSNITELNKRIQ-SVND---ETLLLTQ-------ERDLLK 465
C V+ L+ L+ EK + ITE + ++ +V + E L L Q + + L
Sbjct: 1059 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 1118
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+N+ + A++E Q + + L E L+Q ++LQKN
Sbjct: 1119 DKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNH--------- 1169
Query: 526 EDAVLAKLQEFQEQLDRAE--REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEK 583
+ Q QE LDRA+ + +D + NI Q+L E+ K+E + +
Sbjct: 1170 ---IFRLTQGLQEALDRADLLKTERSDLEYQLENI------QVLYSHEKVKMEGTI--SQ 1218
Query: 584 QREEIKLYRLQLAQ-AAEKLGLLESKVE 610
Q + I + ++ Q A +K GL + E
Sbjct: 1219 QTKLIDFLQAKMDQPAKKKKGLFSRRKE 1246
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 53.2 bits (122), Expect = 3e-06
Identities = 73/332 (21%), Positives = 145/332 (43%), Gaps = 19/332 (5%)
Query: 303 REAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDY 362
RE LR +R E + R+ E+ + + R +++ E +L + L +
Sbjct: 360 REQQLRREQEEERREQQLRR--EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 363 Q-DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI-DVLKENYDTVMRLNKQLTDCVK 420
Q + +QL+ E++ + E + L + +E D LK +T ++ +K
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 421 NLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV-IE 479
+E +E++ + + +R Q + E ++R LK + EER + + E
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR--LKRQEEEERLQQRLRSE 535
Query: 480 QQLC-EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ- 537
QQL E++ + ++LK+ + E + Q L+ ++ E + K+ E+ +L+ Q
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 538 ---------EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
E+++R E+E + RLK + +Q+L+ EEQ + L +Q+E
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER- 654
Query: 589 KLYRLQLAQAAEKLGLLESKVECQRRRRGETA 620
+ RL+ + E+L + + RR E A
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELA 686
Score = 41.1 bits (92), Expect = 0.012
Identities = 64/295 (21%), Positives = 126/295 (42%), Gaps = 26/295 (8%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT-VMRLNKQLTDC 418
H+ + + +QL+ +++ + +L+ + +E + +E + RL +Q +
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE- 525
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVI 478
+ L++ L E+ + +L KR +E L QER + K +E R ++
Sbjct: 526 -ERLQQRLRSEQQLRREQEERREQLLKR-----EEEKRLEQERREQRLKREQEERRDQLL 579
Query: 479 EQQLCEKQNQCS---EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQE 535
+++ +Q + E + EV+ L Q E ++ LK ++ L K +E
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQE-ERREQRLKREEPEEERRQQLLKSEE 638
Query: 536 FQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ---REEIK 589
+E+ R E++ + RLK + +++ R E+ + E + EE+Q RE IK
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 590 ----LYRLQLAQAAE----KLGLLESKVECQRRRRGETAARLHAALQAHWRHALR 636
++ QL A+ K+ K E QRRR+ + R + W+ R
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEER 753
Score = 40.7 bits (91), Expect = 0.016
Identities = 56/261 (21%), Positives = 116/261 (44%), Gaps = 14/261 (5%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
KD + + E L R ++R +K E+ + E +++ ++ +K+ Y+
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
D +++ + + EK+ L+E+ + + + +E +L E +T R ++
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEEL----QQEEEQLLGEERET--RRRQE 1075
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
L + EE L++E+ + +R + +E L +E LL+ + E+ R
Sbjct: 1076 LERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE--REKRR 1132
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
+E+Q E++ EV ++ + L E R+ EL++ + +Q E+ +L + Q
Sbjct: 1133 RQELERQYREEE----EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188
Query: 535 EFQEQ-LDRAEREMENDARLK 554
E + Q +R RE E R K
Sbjct: 1189 EKRRQERERQYREEEELQRQK 1209
Score = 38.7 bits (86), Expect = 0.065
Identities = 53/203 (26%), Positives = 95/203 (46%), Gaps = 14/203 (6%)
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE- 484
L++EK A K ++ L R Q D+ ++R L + R + E++L E
Sbjct: 95 LDEEKRARCDGKESL--LQDRRQE-EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG 151
Query: 485 -KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF--QEQLD 541
+Q++ E L++ D + + RQ E Q+ E + ++QL+ + +EF +EQL
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 542 RAE-REMENDARLKENNIVDSFNKQILRIEEQ---HKLE--INVLEEKQREEIKLYRLQL 595
R E E+ R ++ ++ + EE+ K E + EEK +EE + +L
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 596 AQAAEKLGLLESKVECQRRRRGE 618
+ E+L LE + E +R R+ E
Sbjct: 272 QEEEEQLRKLE-RQELRRERQEE 293
Score = 36.7 bits (81), Expect = 0.26
Identities = 37/165 (22%), Positives = 76/165 (46%), Gaps = 8/165 (4%)
Query: 452 DETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
DE L +E L+ K EE+ +QQ E+Q++ + ++ ++ E ++ +
Sbjct: 206 DEEQLRRRELLELRRKGREEK------QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 512 LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
LQ+ E + + Q E+ L KL+ + + +R E E + +E + ++ R E+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE--RREQ 317
Query: 572 QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
Q + +Q+EE + +L+ Q + L + E +RR +
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQ 362
Score = 34.7 bits (76), Expect = 1.1
Identities = 61/299 (20%), Positives = 125/299 (41%), Gaps = 15/299 (5%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+SE + L+ D Q + ++L +++ +E+ + + S K E + + +
Sbjct: 154 QSEKQERLE-QRDRQRRDEELWRQRQEWQEREERRAEEEQLQ-SCKGHETEEFPD--EEQ 209
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDST--KSNITELNKRIQSVNDETLLLTQERDLLKS 466
+R + L K EE ++ + D + E KR + E L +E +
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 467 KVNEERSRCAVIEQQLCEKQNQCSEV----LKKCDFL---DNEVKTLRQHLELQKNELKC 519
++ EE + +E+Q ++ Q E L++ L E + +Q ++ E +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV 579
+++ E + + +E +EQ R E+E E + + +Q LR E+Q + E +
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 580 LEEKQ-REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALRI 637
E+Q R E +L R Q + ++L E ++ +++ R E H R R+
Sbjct: 390 RREQQLRREQQLRREQQLRREQQL-RREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Score = 34.7 bits (76), Expect = 1.1
Identities = 49/188 (26%), Positives = 78/188 (41%), Gaps = 21/188 (11%)
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
EE LE+E+ + ++ K++ E QE D K EE E+Q
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETD---RKFREEEQLLQEREEQP 1352
Query: 483 CEKQNQC----SEVLKKCD----FLDNEVKTLRQHLEL----QKNELKCHY-QKQLEDAV 529
+Q + E L+ + FL+ E + RQ E ++ +L+C ++QL
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 530 LAKLQEFQEQLDRAER-----EMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
K +E ++QL R ER E E R +E +Q LR E K ++
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 585 REEIKLYR 592
REE +L+R
Sbjct: 1473 REEQQLHR 1480
Score = 33.9 bits (74), Expect = 1.8
Identities = 60/308 (19%), Positives = 135/308 (43%), Gaps = 32/308 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
++ + + E LR R ++R R+ + + + +++ ++ +K+ + Y+
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQ 414
+ +++ + + EK+ +E + + +E +L+E + RL ++
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL----QQEEEQLLREEREK-RRLQER 1046
Query: 415 LTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSR 474
+ E E+E+ + ++ + +R +E L QE + L + E+R R
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE---LQQEEEQLLREEPEKRRR 1103
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN-ELKCHYQKQLEDAVLAKL 533
E++ QC E + + E + LR+ E ++ EL+ Y+++ E +
Sbjct: 1104 Q--------ERERQCRE---EEELQQEEEQLLREEREKRRRQELERQYREEEE------V 1146
Query: 534 QEFQEQLDRAE----REMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
Q+ +EQL R E R E + + +E + +Q+LR E++ + + E + REE +
Sbjct: 1147 QQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER--ERQYREEEE 1204
Query: 590 LYRLQLAQ 597
L R + Q
Sbjct: 1205 LQRQKRKQ 1212
Score = 33.9 bits (74), Expect = 1.8
Identities = 51/251 (20%), Positives = 107/251 (42%), Gaps = 17/251 (6%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
+QL+ E++ E + L +++E ++ D R +QL + E+ L
Sbjct: 1297 EQLEREEQK-EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ--EREEQPL 1353
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
+++ + + + + + +E L QER+ K E++ RC EQQL + +
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER-KFLKEEQQLRCQEREQQLRQDR 1412
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQ-LEDAVLAKLQEFQEQLDRAER 545
++ F + E + RQ + + E + ++Q E L + Q+ +++ R R
Sbjct: 1413 DR--------KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 546 EMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLL 605
E E + +E + + +EE+ +L + K RE+ L+ + K
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ----ELRSQEPERKFLEE 1520
Query: 606 ESKVECQRRRR 616
E ++ Q+R+R
Sbjct: 1521 EQQLHRQQRQR 1531
Score = 33.1 bits (72), Expect = 3.2
Identities = 39/175 (22%), Positives = 76/175 (43%), Gaps = 6/175 (3%)
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK 518
+ER L + + R E++ +++ Q E K+ FL+ E + R+ Q E +
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 519 CHYQKQLE---DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNK--QILRIEEQH 573
Q+ E + Q+++ QL+ ER+ + + + K Q+L+ EE+
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEE-ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912
Query: 574 KLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+ +++E+ + YR + E+ LL + E +RR+ E R LQ
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Score = 32.3 bits (70), Expect = 5.6
Identities = 61/309 (19%), Positives = 133/309 (43%), Gaps = 27/309 (8%)
Query: 315 RAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
R +++ R+ E+ + E +++ ++ +K+ Y+ +++ + EK+
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
+E+ + + + +E +L+E + R + K+ + E++ +
Sbjct: 982 RRQEREKKYREEEEL----QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
K + E ++ + + L QE + L + E R R + Q E++ Q E
Sbjct: 1038 REKRRLQERERQYREEEE----LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE-- 1091
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE-----QLDRAEREMEN 549
L E + R+ Q+ E +C +++L+ L+E +E +L+R RE E
Sbjct: 1092 --QLLREEPEKRRR----QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 550 DARLKENNIVDSFNKQILR-IEEQHKLEINVLEEKQREEIKLYR-LQLAQAAEKLGLLES 607
+ +E + + K+ + +E Q++ E EE Q+EE +L R Q + E+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREE----EELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 608 KVECQRRRR 616
+ E QR++R
Sbjct: 1202 EEELQRQKR 1210
Score = 32.3 bits (70), Expect = 5.6
Identities = 47/244 (19%), Positives = 105/244 (43%), Gaps = 14/244 (5%)
Query: 349 ESELYKTLD-LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
E EL + + L + ++K ++ + E++ EE+ + + + + + L+ Y
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
L ++ ++ +E +E+ + + + KR Q DE +R LK +
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEEL-QRQKRKQRYRDE-----DQRSDLKWQ 1226
Query: 468 VNEERSRCAVIEQQLCE-KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
E+ + C+ ++N+ L+ D + + QHL ++ E +++
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
+ + F E+ ++ ERE + +A+ ++ + KQ+LR E + K + K RE
Sbjct: 1287 QQ---RDRHFPEE-EQLEREEQKEAKRRDRKSQEE--KQLLREEREEKRRRQETDRKFRE 1340
Query: 587 EIKL 590
E +L
Sbjct: 1341 EEQL 1344
Score = 32.3 bits (70), Expect = 5.6
Identities = 66/338 (19%), Positives = 145/338 (42%), Gaps = 36/338 (10%)
Query: 317 EDRHRKALEK--MICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKK 374
++RHRK E+ ++ E E ++ + +K E +L + + + + + E+K
Sbjct: 1457 QERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 375 SLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD 434
LEE+ +++++ + +++ + + L + E+++ +
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFRE-EEQLRQEREEQQLSRQ 1575
Query: 435 STKSNITELNKRIQSVNDETLLLTQERDLLKSK----VNEERSRCAVIEQQLCEKQNQCS 490
++++ E + E+ L + + + +ER R ++QL +++ +
Sbjct: 1576 ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 491 EVLKKCD--FLDNEVKTLRQHLELQ---KNELKCHYQKQL----EDAVLA------KLQE 535
++ D FL+ E + RQ E Q + K ++QL E+ L K +E
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 536 FQEQLDRAERE---MENDARLKENNIVDSFNK--QILRIEEQHKLEIN-----VLEEKQ- 584
++QL R ERE ++ + +L+ + F + Q+ + EQ +L +LEE+Q
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQL 1755
Query: 585 ---REEIKLYRLQLAQAAEKLGLLESKVECQRRRRGET 619
REE +L R + + + L + E Q+ R E+
Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 1898
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 1486 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 1543
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 1544 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1598
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1599 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1658
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1659 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1718
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1719 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1775
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1776 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1812
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/290 (23%), Positives = 118/290 (40%), Gaps = 20/290 (6%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN---LEEA 425
L EK +L L + ++K +E RL ++ D V++ +
Sbjct: 482 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE 541
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
LE+ + + + L K + V + T +RD+L+++ E E E
Sbjct: 542 LERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 601
Query: 486 QNQCSEV-LKKCDFLDN--EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ +++ ++ D+ ++ L + L K +L QLE+ A LQ Q Q ++
Sbjct: 602 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-RLVAQLEEEKSA-LQGRQRQAEQ 659
Query: 543 -AEREMENDARLKENNIVDSFNKQ----ILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
A E RL+E + +Q LR+ EQ + + R E + QLAQ
Sbjct: 660 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 719
Query: 598 AAEKLGLLESKVECQRRRRG------ETAARLHAAL-QAHWRHALRILAA 640
+ +L E ++E RR E AAR AL + H A++++AA
Sbjct: 720 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 769
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 637 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 696
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 697 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 752
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 753 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 809
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 810 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 869
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 870 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 929
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 930 RDEGLLLAESEKQQA---LSLKESE 951
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-coil,
rootletin protein.
Length = 2017
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 1605 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 1662
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 1663 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1717
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1718 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1777
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1778 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1837
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1838 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1894
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1895 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1931
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/290 (23%), Positives = 118/290 (40%), Gaps = 20/290 (6%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN---LEEA 425
L EK +L L + ++K +E RL ++ D V++ +
Sbjct: 601 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE 660
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
LE+ + + + L K + V + T +RD+L+++ E E E
Sbjct: 661 LERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 720
Query: 486 QNQCSEV-LKKCDFLDN--EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ +++ ++ D+ ++ L + L K +L QLE+ A LQ Q Q ++
Sbjct: 721 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-RLVAQLEEEKSA-LQGRQRQAEQ 778
Query: 543 -AEREMENDARLKENNIVDSFNKQ----ILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
A E RL+E + +Q LR+ EQ + + R E + QLAQ
Sbjct: 779 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 838
Query: 598 AAEKLGLLESKVECQRRRRG------ETAARLHAAL-QAHWRHALRILAA 640
+ +L E ++E RR E AAR AL + H A++++AA
Sbjct: 839 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 888
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 756 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 815
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 816 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 871
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 872 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 928
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 929 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 988
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 989 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 1048
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 1049 RDEGLLLAESEKQQA---LSLKESE 1070
Score = 31.9 bits (69), Expect = 7.4
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 17/193 (8%)
Query: 375 SLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
SL+E+ L EL V +L+ E D L Y+ V +Q E E
Sbjct: 78 SLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGL 137
Query: 432 AHDSTK------SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
S + +++Q+ + Q L+ K+ + + RC+ +EQQL E+
Sbjct: 138 VRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLER 197
Query: 486 QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA-VLAKLQEFQEQLDRAE 544
+ L++ D E Q LE L+ Q+ A V A L+E +Q A
Sbjct: 198 SGE----LEQQRLRDTEHS---QDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSAN 250
Query: 545 REMENDARLKENN 557
+ + D R N+
Sbjct: 251 QALSEDIRKVTND 263
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1719
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 956
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 957 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 1016
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 1017 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 1076
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Score = 44.4 bits (100), Expect = 0.001
Identities = 52/306 (16%), Positives = 123/306 (40%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A C++E + + QK
Sbjct: 1122 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDL 1178
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 1179 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 1239 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 1298
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 1356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1417 TKHRLQ 1422
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1706
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1707 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1767 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1820
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1821 ELENELEAEQK 1831
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 53.2 bits (122), Expect = 3e-06
Identities = 78/336 (23%), Positives = 151/336 (44%), Gaps = 43/336 (12%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E L +++ L A ++ +A+ + ++E+ +V + +++ + E ++L Q
Sbjct: 1842 ELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC----Q 1897
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
++ ++ +E+ EQL EL S + ID + R ++ TD + LE
Sbjct: 1898 EELRERLHEESRAREQLAVEL-------SKAEGVIDGYADEKTLFERQIQEKTDIIDRLE 1950
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ L SN R+Q + E + +ER+LL + ++ +EQQL
Sbjct: 1951 QEL--------LCASN------RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 1996
Query: 484 -EKQNQCSEVLK-KC------DFLDNEVKTLRQHLELQKN---ELKCHYQKQLEDAVLAK 532
E + E L+ +C D L +VK L +E Q + EL+ +L D + +
Sbjct: 1997 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMD-LRQQ 2055
Query: 533 LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLEEKQREEIKL 590
Q ++QL++ + ++ A +E+ D F ++I ++E+Q K+ + E Q E++
Sbjct: 2056 NQALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQ 2114
Query: 591 YRLQLAQAAEKLG-LLESKVECQR--RRRGETAARL 623
L + +K LL SK + QR + R E +L
Sbjct: 2115 LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL 2150
Score = 48.0 bits (109), Expect = 1e-04
Identities = 54/258 (20%), Positives = 122/258 (47%), Gaps = 29/258 (11%)
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMR----LNKQLTDCVKNL---EEALEKEKFA 432
+N ++ +N+ L + + + + LKE ++ L +QL D V+ L E +++ +
Sbjct: 491 MNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQT 550
Query: 433 HDSTKSNITELNKRIQSVND---ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+S + E +K + +V D E + ++ R L+ K E + + + L +++N
Sbjct: 551 IAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAV 610
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNE--LKCHYQKQLEDAV-LAKLQE-----FQEQLD 541
+ + + + E++ LR L E K ++E + + KL++ +++Q+D
Sbjct: 611 LD--RMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQID 668
Query: 542 RAEREME---NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ--- 594
+ EM + +++N++ N+ IL I + L+ +++ K E +++ LQ
Sbjct: 669 GLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEI 728
Query: 595 --LAQAAEKLGLLESKVE 610
L Q ++ G LE +V+
Sbjct: 729 EILRQEEKEKGTLEQEVQ 746
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/367 (20%), Positives = 156/367 (42%), Gaps = 23/367 (6%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L EE RE + + + + K I +L + L +N L
Sbjct: 1903 RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQE 1962
Query: 316 AEDRHRKALEK---MICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
E ++ E+ + + E + A +++ +L K L++ + LQ
Sbjct: 1963 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2022
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ K+LE + ++ + K+ E+ L++ L KQL K L+E +
Sbjct: 2023 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQA---LEKQLEKMRKFLDEQAIDREH 2079
Query: 432 AHDSTKSNITELNKRIQSVNDETLLL---TQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
D + I +L ++++ V + T+E + L + + E+ +C+ + + Q
Sbjct: 2080 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 2139
Query: 489 CSEVLKKCDFLDNEVKTLRQHL-----ELQKNELKCHY---QKQLEDAVLAKLQEFQEQL 540
E ++ + L+ V+ L Q L QK E + H+ + + E ++ +LQ ++ +
Sbjct: 2140 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 2199
Query: 541 DRAEREMEN-DARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
DR E+E+ N + +L++ +++ N+++ ++ Q LEI E R +E++
Sbjct: 2200 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ--LEIQKKESTTRLQELEQENKLFKD 2257
Query: 598 AAEKLGL 604
EKLGL
Sbjct: 2258 DMEKLGL 2264
Score = 46.8 bits (106), Expect = 2e-04
Identities = 66/301 (21%), Positives = 140/301 (46%), Gaps = 17/301 (5%)
Query: 326 KMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD 385
+M ++E + D+ K + E+ K DL Q ++E+ +L Q+N EL
Sbjct: 673 EMSQKIETMQFEKDNLITKQNQLILEISKLKDL----QQSLVNSKSEEMTL--QIN-ELQ 725
Query: 386 NVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELN 444
+L ++KE L++ + + L +K E L+ EKFA ++ S + +
Sbjct: 726 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ-EKFAQLEAENSILKDEK 784
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
K ++ + ++QE L+ + +S+ +V E+++ + ++ ++C L+ E++
Sbjct: 785 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIE 844
Query: 505 TLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
R + + +YQ+ Q E A L K+++ E + ++E+E ++LK N + +
Sbjct: 845 KQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLED-SKNKQELEYKSKLKALN--EELH 901
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK-LGLLESKVECQRRRRGETAAR 622
Q + K++ +V +E + L++ + EK L K+E +R + E + R
Sbjct: 902 LQRIN-PTTVKMKSSVFDED--KTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQR 958
Query: 623 L 623
L
Sbjct: 959 L 959
Score = 45.2 bits (102), Expect = 7e-04
Identities = 73/308 (23%), Positives = 129/308 (41%), Gaps = 35/308 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC---KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
Q + + EL D A + Q++ K + E KS Q EL+ KE+
Sbjct: 3131 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 3190
Query: 399 DV----LKENYDTVMRLNKQLTDCVKNLEE---ALEKEKF----AHDSTKSNITELNKRI 447
+ +K+ D V LN L K E ALEKEK + + K + +L +
Sbjct: 3191 EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSL 3250
Query: 448 QSVNDETL----LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+S L LL Q++ LL + S+ + + QL E+Q + E+ L++E
Sbjct: 3251 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV---LLESEK 3307
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+R+ E + H Q Q D + +E++ K + IV+ N
Sbjct: 3308 VRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--EDLLKELQKQLEEKHSRIVELLN 3365
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYR--LQLAQAA-----EKLGLLESKVECQRRRR 616
+ E++KL+ ++ ++ +++R LQ Q A +K+ L+SKVE +R+
Sbjct: 3366 E-----TEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3420
Query: 617 GETAARLH 624
E +++
Sbjct: 3421 EEKRQQVY 3428
Score = 44.0 bits (99), Expect = 0.002
Identities = 76/344 (22%), Positives = 147/344 (42%), Gaps = 30/344 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A K+ A S+L A + T + + + ++A E + C+ E R + +
Sbjct: 1853 AAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQ-EELRERLHEESRAR 1911
Query: 346 SHFESELYKTLDLAHDYQDKC----KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
EL K + Y D+ +Q+Q EK + ++L EL + L + E +
Sbjct: 1912 EQLAVELSKAEGVIDGYADEKTLFERQIQ-EKTDIIDRLEQELLCASNRLQELEAEQQQI 1970
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+E + + R + + +E+ L +E + E+ + + V D+ L ++
Sbjct: 1971 QEERELLSRQKEAMKAEAGPVEQQLLQET---EKLMKEKLEVQCQAEKVRDD---LQKQV 2024
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ---KNELK 518
L+ V E+ SR +EQ EK + ++ ++ L+ +++ +R+ L+ Q + +
Sbjct: 2025 KALEIDVEEQVSRFIELEQ---EKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER 2081
Query: 519 CHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDAR-LKENNIVDS---FNKQIL----- 567
+Q++++ + L + FQ + RE+E A LKE S +K+ L
Sbjct: 2082 DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 2141
Query: 568 -RIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
R EE KLE V E +Q + Q + + G +E+K E
Sbjct: 2142 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 2185
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 8/209 (3%)
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
TEL V EID EN + ++ ++ +L V+ L EA+ + + K T
Sbjct: 1820 TELSQRLVRSGFAGTEID--PENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQT 1877
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
EL + E + ++ L+ +++EE + +L + + + +
Sbjct: 1878 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1937
Query: 502 EVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+++ ++ + EL C + E +A ++QE +E L R + M+ +A E ++
Sbjct: 1938 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 1997
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
K + + KLE+ EK R++++
Sbjct: 1998 ETEKLM-----KEKLEVQCQAEKVRDDLQ 2021
Score = 41.5 bits (93), Expect = 0.009
Identities = 52/239 (21%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L Y+ + LQNE E + E DN+ + K+N ++ ++K
Sbjct: 658 NLGIHYKQQIDGLQNEMSQKIETMQFEKDNL------------ITKQN-QLILEISK--- 701
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
+K+L+++L K + I EL K I+ + E +E+ L+ +V E + +
Sbjct: 702 --LKDLQQSLVNSK--SEEMTLQINELQKEIEILRQE----EKEKGTLEQEVQELQLKTE 753
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++E+Q+ EK+N E K L+ E L+ + ++ LK H E+ ++ L
Sbjct: 754 LLEKQMKEKENDLQE---KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-LDSI 809
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ 594
+ + + E E + ++EN + +Q +++ E+ + + N ++ E+ LQ
Sbjct: 810 KSKSKDSVWEKEIEILIEEN---EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Score = 39.5 bits (88), Expect = 0.037
Identities = 62/273 (22%), Positives = 118/273 (43%), Gaps = 28/273 (10%)
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ K S +E E+ ++ D + +C QL E +E+Q NT + N +
Sbjct: 811 SKSKDSVWEKEIEILIEENEDLKQQCIQLNEE---IEKQRNT----FSFAEKNFEVNYQE 863
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN----KRIQSVNDETLL 456
L+E Y ++++ L D KN +E K K + + ++ +N K SV DE
Sbjct: 864 LQEEYACLLKVKDDLEDS-KNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKT 922
Query: 457 LTQER----DLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLK----KCDFLDNEVKT 505
E ++++ E + V +++ L ++ + SE LK + FL+ EVK+
Sbjct: 923 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLNEEVKS 982
Query: 506 LRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
L+ E L+ EL+ + V + + LD A + + SF
Sbjct: 983 LKPEKEPVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSF 1042
Query: 563 NKQI-LRIEEQHKLE-INVLEEKQREEIKLYRL 593
++ + +E++ E + V EE ++E++ L L
Sbjct: 1043 GEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1075
Score = 38.7 bits (86), Expect = 0.065
Identities = 52/265 (19%), Positives = 108/265 (40%), Gaps = 24/265 (9%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNV 389
++ V D ++ + + +L T D +K + +NE + LE Q+ + +
Sbjct: 2288 IQEKEVEIDQLNEQVTKLQQQLKITTD------NKVIEEKNELIRDLETQIECLMSDQEC 2341
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
+ N+++EI+ L E + +L ++L + + DS K + + +
Sbjct: 2342 VKRNREEEIEQLNE---VIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 2398
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + +E +K+ + E + + Q+L + + V K +N V H
Sbjct: 2399 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2458
Query: 510 LELQKNELKC----HYQKQLEDAVLAKLQEFQE-------QLDRAEREMENDARLKENNI 558
L K EL+ K LE+ K F+E L+ ++E+ K+ +
Sbjct: 2459 LSKDKPELEVVLTEDALKSLENQTYFK--SFEENGKGSIINLETRLLQLESTVSAKDLEL 2516
Query: 559 VDSFNKQILRIEEQHKLEINVLEEK 583
+ KQI ++EQ + E +L++K
Sbjct: 2517 TQCY-KQIKDMQEQGQFETEMLQKK 2540
Score = 35.9 bits (79), Expect = 0.46
Identities = 68/306 (22%), Positives = 128/306 (41%), Gaps = 36/306 (11%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK--KSL 376
R R+++EK+ EN VA D K E E+ T +D K L+N+ KS
Sbjct: 2436 RERESVEKIQSIPENSVNVAIDHLSKDKP-ELEVVLT-------EDALKSLENQTYFKSF 2487
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE + N+ L + TV + +LT C K +++ E+ +F +
Sbjct: 2488 EENGKGSIINLETRLLQLES----------TVSAKDLELTQCYKQIKDMQEQGQFETEML 2537
Query: 437 KSNITELNKRIQS------VNDETLLLTQE-----RDLLKSKVNEERSRCAVIEQ-QLCE 484
+ I L K ++ V+ L QE +D ER+ + Q + E
Sbjct: 2538 QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDE 2597
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRA 543
+ S + + L+++V + L L+K +++ + LE + L +LQ+ E ++
Sbjct: 2598 LGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKK 2657
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
+RE E ++ ++ + ++ E+ N LE + E + + +LA EK
Sbjct: 2658 QREKEKKRSPQDVEVLKT-TTELFHSNEESGF-FNELEALRAESVAT-KAELASYKEKAE 2714
Query: 604 LLESKV 609
L+ ++
Sbjct: 2715 KLQEEL 2720
Score = 33.1 bits (72), Expect = 3.2
Identities = 41/213 (19%), Positives = 97/213 (45%), Gaps = 13/213 (6%)
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
E+ +E + K++ L IQ+++ + + + LK + E+ ++E +
Sbjct: 3071 EQGVEYQAAMECLQKADRRSLLSEIQALHAQ---MNGRKITLKREQESEKPSQELLEYNI 3127
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN---ELKCHYQK---QLEDAVLAKLQEF 536
+KQ+Q E+ + + + L++ L +K ELK + +LE + A+ +
Sbjct: 3128 QQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHL 3187
Query: 537 QE-QLDRAEREMENDARLKENNIVDSFNKQILRIE---EQHKLEINVLEEKQREEIKLYR 592
+E + R E + + D N+ + S K+ ++ E+ K ++ EE+ +EE++ +
Sbjct: 3188 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK 3247
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHA 625
L ++ L +E Q++ E+ ++ +
Sbjct: 3248 FSLESQKQRNLQLNLLLEQQKQLLNESQQKIES 3280
Score = 32.3 bits (70), Expect = 5.6
Identities = 20/123 (16%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE-EALEKEKF 431
++S+ ++++ + + L +++++ +++ + ++Q T+ ++ +E+++
Sbjct: 1563 RQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMPQMERQRE 1622
Query: 432 AHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
+ + I LN+++ S+++E L+ +ER LL+ ++ A E+ CE +N
Sbjct: 1623 DQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNS 1682
Query: 489 CSE 491
++
Sbjct: 1683 STQ 1685
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 53.2 bits (122), Expect = 3e-06
Identities = 78/336 (23%), Positives = 151/336 (44%), Gaps = 43/336 (12%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E L +++ L A ++ +A+ + ++E+ +V + +++ + E ++L Q
Sbjct: 1853 ELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC----Q 1908
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
++ ++ +E+ EQL EL S + ID + R ++ TD + LE
Sbjct: 1909 EELRERLHEESRAREQLAVEL-------SKAEGVIDGYADEKTLFERQIQEKTDIIDRLE 1961
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ L SN R+Q + E + +ER+LL + ++ +EQQL
Sbjct: 1962 QEL--------LCASN------RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 2007
Query: 484 -EKQNQCSEVLK-KC------DFLDNEVKTLRQHLELQKN---ELKCHYQKQLEDAVLAK 532
E + E L+ +C D L +VK L +E Q + EL+ +L D + +
Sbjct: 2008 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMD-LRQQ 2066
Query: 533 LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLEEKQREEIKL 590
Q ++QL++ + ++ A +E+ D F ++I ++E+Q K+ + E Q E++
Sbjct: 2067 NQALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQ 2125
Query: 591 YRLQLAQAAEKLG-LLESKVECQR--RRRGETAARL 623
L + +K LL SK + QR + R E +L
Sbjct: 2126 LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL 2161
Score = 48.0 bits (109), Expect = 1e-04
Identities = 54/258 (20%), Positives = 122/258 (47%), Gaps = 29/258 (11%)
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMR----LNKQLTDCVKNL---EEALEKEKFA 432
+N ++ +N+ L + + + + LKE ++ L +QL D V+ L E +++ +
Sbjct: 503 MNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQT 562
Query: 433 HDSTKSNITELNKRIQSVND---ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+S + E +K + +V D E + ++ R L+ K E + + + L +++N
Sbjct: 563 IAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAV 622
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNE--LKCHYQKQLEDAV-LAKLQE-----FQEQLD 541
+ + + + E++ LR L E K ++E + + KL++ +++Q+D
Sbjct: 623 LD--RMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQID 680
Query: 542 RAEREME---NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ--- 594
+ EM + +++N++ N+ IL I + L+ +++ K E +++ LQ
Sbjct: 681 GLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEI 740
Query: 595 --LAQAAEKLGLLESKVE 610
L Q ++ G LE +V+
Sbjct: 741 EILRQEEKEKGTLEQEVQ 758
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/367 (20%), Positives = 156/367 (42%), Gaps = 23/367 (6%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L EE RE + + + + K I +L + L +N L
Sbjct: 1914 RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQE 1973
Query: 316 AEDRHRKALEK---MICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
E ++ E+ + + E + A +++ +L K L++ + LQ
Sbjct: 1974 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 2033
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ K+LE + ++ + K+ E+ L++ L KQL K L+E +
Sbjct: 2034 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQA---LEKQLEKMRKFLDEQAIDREH 2090
Query: 432 AHDSTKSNITELNKRIQSVNDETLLL---TQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
D + I +L ++++ V + T+E + L + + E+ +C+ + + Q
Sbjct: 2091 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 2150
Query: 489 CSEVLKKCDFLDNEVKTLRQHL-----ELQKNELKCHY---QKQLEDAVLAKLQEFQEQL 540
E ++ + L+ V+ L Q L QK E + H+ + + E ++ +LQ ++ +
Sbjct: 2151 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 2210
Query: 541 DRAEREMEN-DARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
DR E+E+ N + +L++ +++ N+++ ++ Q LEI E R +E++
Sbjct: 2211 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ--LEIQKKESTTRLQELEQENKLFKD 2268
Query: 598 AAEKLGL 604
EKLGL
Sbjct: 2269 DMEKLGL 2275
Score = 46.8 bits (106), Expect = 2e-04
Identities = 66/301 (21%), Positives = 140/301 (46%), Gaps = 17/301 (5%)
Query: 326 KMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD 385
+M ++E + D+ K + E+ K DL Q ++E+ +L Q+N EL
Sbjct: 685 EMSQKIETMQFEKDNLITKQNQLILEISKLKDL----QQSLVNSKSEEMTL--QIN-ELQ 737
Query: 386 NVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELN 444
+L ++KE L++ + + L +K E L+ EKFA ++ S + +
Sbjct: 738 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ-EKFAQLEAENSILKDEK 796
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
K ++ + ++QE L+ + +S+ +V E+++ + ++ ++C L+ E++
Sbjct: 797 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIE 856
Query: 505 TLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
R + + +YQ+ Q E A L K+++ E + ++E+E ++LK N + +
Sbjct: 857 KQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLED-SKNKQELEYKSKLKALN--EELH 913
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK-LGLLESKVECQRRRRGETAAR 622
Q + K++ +V +E + L++ + EK L K+E +R + E + R
Sbjct: 914 LQRIN-PTTVKMKSSVFDED--KTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQR 970
Query: 623 L 623
L
Sbjct: 971 L 971
Score = 45.2 bits (102), Expect = 7e-04
Identities = 73/308 (23%), Positives = 129/308 (41%), Gaps = 35/308 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC---KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
Q + + EL D A + Q++ K + E KS Q EL+ KE+
Sbjct: 3134 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 3193
Query: 399 DV----LKENYDTVMRLNKQLTDCVKNLEE---ALEKEKF----AHDSTKSNITELNKRI 447
+ +K+ D V LN L K E ALEKEK + + K + +L +
Sbjct: 3194 EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSL 3253
Query: 448 QSVNDETL----LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+S L LL Q++ LL + S+ + + QL E+Q + E+ L++E
Sbjct: 3254 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV---LLESEK 3310
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+R+ E + H Q Q D + +E++ K + IV+ N
Sbjct: 3311 VRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--EDLLKELQKQLEEKHSRIVELLN 3368
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYR--LQLAQAA-----EKLGLLESKVECQRRRR 616
+ E++KL+ ++ ++ +++R LQ Q A +K+ L+SKVE +R+
Sbjct: 3369 E-----TEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3423
Query: 617 GETAARLH 624
E +++
Sbjct: 3424 EEKRQQVY 3431
Score = 44.0 bits (99), Expect = 0.002
Identities = 76/344 (22%), Positives = 147/344 (42%), Gaps = 30/344 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A K+ A S+L A + T + + + ++A E + C+ E R + +
Sbjct: 1864 AAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQ-EELRERLHEESRAR 1922
Query: 346 SHFESELYKTLDLAHDYQDKC----KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
EL K + Y D+ +Q+Q EK + ++L EL + L + E +
Sbjct: 1923 EQLAVELSKAEGVIDGYADEKTLFERQIQ-EKTDIIDRLEQELLCASNRLQELEAEQQQI 1981
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+E + + R + + +E+ L +E + E+ + + V D+ L ++
Sbjct: 1982 QEERELLSRQKEAMKAEAGPVEQQLLQET---EKLMKEKLEVQCQAEKVRDD---LQKQV 2035
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ---KNELK 518
L+ V E+ SR +EQ EK + ++ ++ L+ +++ +R+ L+ Q + +
Sbjct: 2036 KALEIDVEEQVSRFIELEQ---EKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER 2092
Query: 519 CHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDAR-LKENNIVDS---FNKQIL----- 567
+Q++++ + L + FQ + RE+E A LKE S +K+ L
Sbjct: 2093 DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 2152
Query: 568 -RIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
R EE KLE V E +Q + Q + + G +E+K E
Sbjct: 2153 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 2196
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 8/209 (3%)
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
TEL V EID EN + ++ ++ +L V+ L EA+ + + K T
Sbjct: 1831 TELSQRLVRSGFAGTEID--PENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQT 1888
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
EL + E + ++ L+ +++EE + +L + + + +
Sbjct: 1889 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1948
Query: 502 EVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+++ ++ + EL C + E +A ++QE +E L R + M+ +A E ++
Sbjct: 1949 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 2008
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
K + + KLE+ EK R++++
Sbjct: 2009 ETEKLM-----KEKLEVQCQAEKVRDDLQ 2032
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/273 (23%), Positives = 119/273 (43%), Gaps = 28/273 (10%)
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ K S +E E+ ++ D + +C QL E +E+Q NT + N +
Sbjct: 823 SKSKDSVWEKEIEILIEENEDLKQQCIQLNEE---IEKQRNT----FSFAEKNFEVNYQE 875
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN----KRIQSVNDETLL 456
L+E Y ++++ L D KN +E K K + + ++ +N K SV DE
Sbjct: 876 LQEEYACLLKVKDDLEDS-KNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKT 934
Query: 457 LTQER----DLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKK----CDFLDNEVKT 505
E ++++ E + V +++ L ++ + SE LK+ FL+ EVK+
Sbjct: 935 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 994
Query: 506 LRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
L+Q E L+ EL+ + V + + LD A + + SF
Sbjct: 995 LKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSF 1054
Query: 563 NKQI-LRIEEQHKLE-INVLEEKQREEIKLYRL 593
++ + +E++ E + V EE ++E++ L L
Sbjct: 1055 GEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1087
Score = 41.5 bits (93), Expect = 0.009
Identities = 52/239 (21%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L Y+ + LQNE E + E DN+ + K+N ++ ++K
Sbjct: 670 NLGIHYKQQIDGLQNEMSQKIETMQFEKDNL------------ITKQN-QLILEISK--- 713
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
+K+L+++L K + I EL K I+ + E +E+ L+ +V E + +
Sbjct: 714 --LKDLQQSLVNSK--SEEMTLQINELQKEIEILRQE----EKEKGTLEQEVQELQLKTE 765
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++E+Q+ EK+N E K L+ E L+ + ++ LK H E+ ++ L
Sbjct: 766 LLEKQMKEKENDLQE---KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-LDSI 821
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ 594
+ + + E E + ++EN + +Q +++ E+ + + N ++ E+ LQ
Sbjct: 822 KSKSKDSVWEKEIEILIEEN---EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 877
Score = 38.7 bits (86), Expect = 0.065
Identities = 52/265 (19%), Positives = 108/265 (40%), Gaps = 24/265 (9%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNV 389
++ V D ++ + + +L T D +K + +NE + LE Q+ + +
Sbjct: 2299 IQEKEVEIDQLNEQVTKLQQQLKITTD------NKVIEEKNELIRDLETQIECLMSDQEC 2352
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
+ N+++EI+ L E + +L ++L + + DS K + + +
Sbjct: 2353 VKRNREEEIEQLNE---VIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 2409
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + +E +K+ + E + + Q+L + + V K +N V H
Sbjct: 2410 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2469
Query: 510 LELQKNELKC----HYQKQLEDAVLAKLQEFQE-------QLDRAEREMENDARLKENNI 558
L K EL+ K LE+ K F+E L+ ++E+ K+ +
Sbjct: 2470 LSKDKPELEVVLTEDALKSLENQTYFK--SFEENGKGSIINLETRLLQLESTVSAKDLEL 2527
Query: 559 VDSFNKQILRIEEQHKLEINVLEEK 583
+ KQI ++EQ + E +L++K
Sbjct: 2528 TQCY-KQIKDMQEQGQFETEMLQKK 2551
Score = 35.9 bits (79), Expect = 0.46
Identities = 68/306 (22%), Positives = 128/306 (41%), Gaps = 36/306 (11%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK--KSL 376
R R+++EK+ EN VA D K E E+ T +D K L+N+ KS
Sbjct: 2447 RERESVEKIQSIPENSVNVAIDHLSKDKP-ELEVVLT-------EDALKSLENQTYFKSF 2498
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE + N+ L + TV + +LT C K +++ E+ +F +
Sbjct: 2499 EENGKGSIINLETRLLQLES----------TVSAKDLELTQCYKQIKDMQEQGQFETEML 2548
Query: 437 KSNITELNKRIQS------VNDETLLLTQE-----RDLLKSKVNEERSRCAVIEQ-QLCE 484
+ I L K ++ V+ L QE +D ER+ + Q + E
Sbjct: 2549 QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDE 2608
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRA 543
+ S + + L+++V + L L+K +++ + LE + L +LQ+ E ++
Sbjct: 2609 LGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKK 2668
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
+RE E ++ ++ + ++ E+ N LE + E + + +LA EK
Sbjct: 2669 QREKEKKRSPQDVEVLKT-TTELFHSNEESGF-FNELEALRAESVAT-KAELASYKEKAE 2725
Query: 604 LLESKV 609
L+ ++
Sbjct: 2726 KLQEEL 2731
Score = 33.1 bits (72), Expect = 3.2
Identities = 41/213 (19%), Positives = 97/213 (45%), Gaps = 13/213 (6%)
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
E+ +E + K++ L IQ+++ + + + LK + E+ ++E +
Sbjct: 3074 EQGVEYQAAMECLQKADRRSLLSEIQALHAQ---MNGRKITLKREQESEKPSQELLEYNI 3130
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN---ELKCHYQK---QLEDAVLAKLQEF 536
+KQ+Q E+ + + + L++ L +K ELK + +LE + A+ +
Sbjct: 3131 QQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHL 3190
Query: 537 QE-QLDRAEREMENDARLKENNIVDSFNKQILRIE---EQHKLEINVLEEKQREEIKLYR 592
+E + R E + + D N+ + S K+ ++ E+ K ++ EE+ +EE++ +
Sbjct: 3191 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK 3250
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHA 625
L ++ L +E Q++ E+ ++ +
Sbjct: 3251 FSLESQKQRNLQLNLLLEQQKQLLNESQQKIES 3283
Score = 32.7 bits (71), Expect = 4.2
Identities = 20/123 (16%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE-EALEKEKF 431
++S+ ++++ + + L +++++ +++ + ++Q T+ ++ +E+++
Sbjct: 1574 RQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQRE 1633
Query: 432 AHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
+ + I LN+++ S+++E L+ +ER LL+ ++ A E+ CE +N
Sbjct: 1634 DQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNS 1693
Query: 489 CSE 491
++
Sbjct: 1694 STQ 1696
>AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen
MU-MB-2.42 protein.
Length = 439
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 34 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 91
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 92 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 146
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 147 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 206
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 207 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 266
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 267 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 323
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 324 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 360
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 53.2 bits (122), Expect = 3e-06
Identities = 77/337 (22%), Positives = 151/337 (44%), Gaps = 45/337 (13%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E L +++ L A ++ +A+ + ++E+ +V + +++ + E ++L Q
Sbjct: 1529 ELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC----Q 1584
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
++ ++ +E+ EQL EL S + ID + R ++ TD + LE
Sbjct: 1585 EELRERLHEESRAREQLAVEL-------SKAEGVIDGYADEKTLFERQIQEKTDIIDRLE 1637
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ L SN R+Q + E + +ER+LL + ++ +EQQL
Sbjct: 1638 QEL--------LCASN------RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 1683
Query: 484 EK---------QNQCSEVLKKCDFLDNEVKTLRQHLELQKN---ELKCHYQKQLEDAVLA 531
++ + QC + K D L +VK L +E Q + EL+ +L D +
Sbjct: 1684 QETEKLMKEKLEVQC-QAEKDRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMD-LRQ 1741
Query: 532 KLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLEEKQREEIK 589
+ Q ++QL++ + ++ A +E+ D F ++I ++E+Q K+ + E Q E++
Sbjct: 1742 QNQALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVE 1800
Query: 590 LYRLQLAQAAEKLG-LLESKVECQR--RRRGETAARL 623
L + +K LL SK + QR + R E +L
Sbjct: 1801 QLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL 1837
Score = 48.0 bits (109), Expect = 1e-04
Identities = 54/258 (20%), Positives = 122/258 (47%), Gaps = 29/258 (11%)
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMR----LNKQLTDCVKNL---EEALEKEKFA 432
+N ++ +N+ L + + + + LKE ++ L +QL D V+ L E +++ +
Sbjct: 181 MNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQT 240
Query: 433 HDSTKSNITELNKRIQSVND---ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+S + E +K + +V D E + ++ R L+ K E + + + L +++N
Sbjct: 241 IAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAV 300
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNE--LKCHYQKQLEDAV-LAKLQE-----FQEQLD 541
+ + + + E++ LR L E K ++E + + KL++ +++Q+D
Sbjct: 301 LD--RMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQID 358
Query: 542 RAEREME---NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ--- 594
+ EM + +++N++ N+ IL I + L+ +++ K E +++ LQ
Sbjct: 359 GLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEI 418
Query: 595 --LAQAAEKLGLLESKVE 610
L Q ++ G LE +V+
Sbjct: 419 EILRQEEKEKGTLEQEVQ 436
Score = 47.6 bits (108), Expect = 1e-04
Identities = 75/367 (20%), Positives = 156/367 (42%), Gaps = 23/367 (6%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L EE RE + + + + K I +L + L +N L
Sbjct: 1590 RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQE 1649
Query: 316 AEDRHRKALEK---MICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
E ++ E+ + + E + A +++ +L K L++ + LQ
Sbjct: 1650 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKDRDDLQK 1709
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ K+LE + ++ + K+ E+ L++ L KQL K L+E +
Sbjct: 1710 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQA---LEKQLEKMRKFLDEQAIDREH 1766
Query: 432 AHDSTKSNITELNKRIQSVNDETLLL---TQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
D + I +L ++++ V + T+E + L + + E+ +C+ + + Q
Sbjct: 1767 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 1826
Query: 489 CSEVLKKCDFLDNEVKTLRQHL-----ELQKNELKCHY---QKQLEDAVLAKLQEFQEQL 540
E ++ + L+ V+ L Q L QK E + H+ + + E ++ +LQ ++ +
Sbjct: 1827 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 1886
Query: 541 DRAEREMEN-DARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
DR E+E+ N + +L++ +++ N+++ ++ Q LEI E R +E++
Sbjct: 1887 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ--LEIQKKESTTRLQELEQENKLFKD 1944
Query: 598 AAEKLGL 604
EKLGL
Sbjct: 1945 DMEKLGL 1951
Score = 46.8 bits (106), Expect = 2e-04
Identities = 66/301 (21%), Positives = 140/301 (46%), Gaps = 17/301 (5%)
Query: 326 KMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD 385
+M ++E + D+ K + E+ K DL Q ++E+ +L Q+N EL
Sbjct: 363 EMSQKIETMQFEKDNLITKQNQLILEISKLKDL----QQSLVNSKSEEMTL--QIN-ELQ 415
Query: 386 NVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH-DSTKSNITELN 444
+L ++KE L++ + + L +K E L+ EKFA ++ S + +
Sbjct: 416 KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ-EKFAQLEAENSILKDEK 474
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
K ++ + ++QE L+ + +S+ +V E+++ + ++ ++C L+ E++
Sbjct: 475 KTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIE 534
Query: 505 TLRQHLELQKNELKCHYQK-QLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
R + + +YQ+ Q E A L K+++ E + ++E+E ++LK N + +
Sbjct: 535 KQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLED-SKNKQELEYKSKLKALN--EELH 591
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEK-LGLLESKVECQRRRRGETAAR 622
Q + K++ +V +E + L++ + EK L K+E +R + E + R
Sbjct: 592 LQRIN-PTTVKMKSSVFDED--KTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQR 648
Query: 623 L 623
L
Sbjct: 649 L 649
Score = 45.2 bits (102), Expect = 7e-04
Identities = 73/308 (23%), Positives = 129/308 (41%), Gaps = 35/308 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC---KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
Q + + EL D A + Q++ K + E KS Q EL+ KE+
Sbjct: 2818 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 2877
Query: 399 DV----LKENYDTVMRLNKQLTDCVKNLEE---ALEKEKF----AHDSTKSNITELNKRI 447
+ +K+ D V LN L K E ALEKEK + + K + +L +
Sbjct: 2878 EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSL 2937
Query: 448 QSVNDETL----LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+S L LL Q++ LL + S+ + + QL E+Q + E+ L++E
Sbjct: 2938 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV---LLESEK 2994
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+R+ E + H Q Q D + +E++ K + IV+ N
Sbjct: 2995 VRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--EDLLKELQKQLEEKHSRIVELLN 3052
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYR--LQLAQAA-----EKLGLLESKVECQRRRR 616
+ E++KL+ ++ ++ +++R LQ Q A +K+ L+SKVE +R+
Sbjct: 3053 E-----TEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3107
Query: 617 GETAARLH 624
E +++
Sbjct: 3108 EEKRQQVY 3115
Score = 44.8 bits (101), Expect = 0.001
Identities = 77/344 (22%), Positives = 149/344 (43%), Gaps = 30/344 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A K+ A S+L A + T + + + ++A E + C+ E R + +
Sbjct: 1540 AAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQ-EELRERLHEESRAR 1598
Query: 346 SHFESELYKTLDLAHDYQDKC----KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
EL K + Y D+ +Q+Q EK + ++L EL + SN+ +E++
Sbjct: 1599 EQLAVELSKAEGVIDGYADEKTLFERQIQ-EKTDIIDRLEQEL----LCASNRLQELEAE 1653
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
++ L + + +K E +++ ++ K +L + Q+ D L Q +
Sbjct: 1654 QQQIQEERELLSRQKEAMK-AEAGPVEQQLLQETEKLMKEKLEVQCQAEKDRDDLQKQVK 1712
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ---KNELK 518
L+ V E+ SR +EQ EK + ++ ++ L+ +++ +R+ L+ Q + +
Sbjct: 1713 -ALEIDVEEQVSRFIELEQ---EKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER 1768
Query: 519 CHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDAR-LKENNIVDS---FNKQIL----- 567
+Q++++ + L + FQ + RE+E A LKE S +K+ L
Sbjct: 1769 DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 1828
Query: 568 -RIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
R EE KLE V E +Q + Q + + G +E+K E
Sbjct: 1829 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 1872
Score = 44.4 bits (100), Expect = 0.001
Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 8/209 (3%)
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
TEL V EID EN + ++ ++ +L V+ L EA+ + + K T
Sbjct: 1507 TELSQRLVRSGFAGTEID--PENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQT 1564
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
EL + E + ++ L+ +++EE + +L + + + +
Sbjct: 1565 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 1624
Query: 502 EVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+++ ++ + EL C + E +A ++QE +E L R + M+ +A E ++
Sbjct: 1625 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 1684
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
K + + KLE+ EK R++++
Sbjct: 1685 ETEKLM-----KEKLEVQCQAEKDRDDLQ 1708
Score = 41.9 bits (94), Expect = 0.007
Identities = 63/273 (23%), Positives = 119/273 (43%), Gaps = 28/273 (10%)
Query: 341 AQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDV 400
++ K S +E E+ ++ D + +C QL E +E+Q NT + N +
Sbjct: 501 SKSKDSVWEKEIEILIEENEDLKQQCIQLNEE---IEKQRNT----FSFAEKNFEVNYQE 553
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELN----KRIQSVNDETLL 456
L+E Y ++++ L D KN +E K K + + ++ +N K SV DE
Sbjct: 554 LQEEYACLLKVKDDLEDS-KNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKT 612
Query: 457 LTQER----DLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKK----CDFLDNEVKT 505
E ++++ E + V +++ L ++ + SE LK+ FL+ EVK+
Sbjct: 613 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 672
Query: 506 LRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
L+Q E L+ EL+ + V + + LD A + + SF
Sbjct: 673 LKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSF 732
Query: 563 NKQI-LRIEEQHKLE-INVLEEKQREEIKLYRL 593
++ + +E++ E + V EE ++E++ L L
Sbjct: 733 GEESKIMVEDKVSFENMTVGEESKQEQLILDHL 765
Score = 41.5 bits (93), Expect = 0.009
Identities = 52/239 (21%), Positives = 107/239 (44%), Gaps = 32/239 (13%)
Query: 357 DLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
+L Y+ + LQNE E + E DN+ + K+N ++ ++K
Sbjct: 348 NLGIHYKQQIDGLQNEMSQKIETMQFEKDNL------------ITKQN-QLILEISK--- 391
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
+K+L+++L K + I EL K I+ + E +E+ L+ +V E + +
Sbjct: 392 --LKDLQQSLVNSK--SEEMTLQINELQKEIEILRQE----EKEKGTLEQEVQELQLKTE 443
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEF 536
++E+Q+ EK+N E K L+ E L+ + ++ LK H E+ ++ L
Sbjct: 444 LLEKQMKEKENDLQE---KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF-LDSI 499
Query: 537 QEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQRE-EIKLYRLQ 594
+ + + E E + ++EN + +Q +++ E+ + + N ++ E+ LQ
Sbjct: 500 KSKSKDSVWEKEIEILIEEN---EDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 555
Score = 38.7 bits (86), Expect = 0.065
Identities = 52/265 (19%), Positives = 108/265 (40%), Gaps = 24/265 (9%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNV 389
++ V D ++ + + +L T D +K + +NE + LE Q+ + +
Sbjct: 1975 IQEKEVEIDQLNEQVTKLQQQLKITTD------NKVIEEKNELIRDLETQIECLMSDQEC 2028
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
+ N+++EI+ L E + +L ++L + + DS K + + +
Sbjct: 2029 VKRNREEEIEQLNE---VIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 2085
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + +E +K+ + E + + Q+L + + V K +N V H
Sbjct: 2086 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 2145
Query: 510 LELQKNELKC----HYQKQLEDAVLAKLQEFQE-------QLDRAEREMENDARLKENNI 558
L K EL+ K LE+ K F+E L+ ++E+ K+ +
Sbjct: 2146 LSKDKPELEVVLTEDALKSLENQTYFK--SFEENGKGSIINLETRLLQLESTVSAKDLEL 2203
Query: 559 VDSFNKQILRIEEQHKLEINVLEEK 583
+ KQI ++EQ + E +L++K
Sbjct: 2204 TQCY-KQIKDMQEQGQFETEMLQKK 2227
Score = 35.9 bits (79), Expect = 0.46
Identities = 68/306 (22%), Positives = 128/306 (41%), Gaps = 36/306 (11%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK--KSL 376
R R+++EK+ EN VA D K E E+ T +D K L+N+ KS
Sbjct: 2123 RERESVEKIQSIPENSVNVAIDHLSKDKP-ELEVVLT-------EDALKSLENQTYFKSF 2174
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE + N+ L + TV + +LT C K +++ E+ +F +
Sbjct: 2175 EENGKGSIINLETRLLQLES----------TVSAKDLELTQCYKQIKDMQEQGQFETEML 2224
Query: 437 KSNITELNKRIQS------VNDETLLLTQE-----RDLLKSKVNEERSRCAVIEQ-QLCE 484
+ I L K ++ V+ L QE +D ER+ + Q + E
Sbjct: 2225 QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDE 2284
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRA 543
+ S + + L+++V + L L+K +++ + LE + L +LQ+ E ++
Sbjct: 2285 LGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKK 2344
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
+RE E ++ ++ + ++ E+ N LE + E + + +LA EK
Sbjct: 2345 QREKEKKRSPQDVEVLKT-TTELFHSNEESGF-FNELEALRAESVAT-KAELASYKEKAE 2401
Query: 604 LLESKV 609
L+ ++
Sbjct: 2402 KLQEEL 2407
Score = 33.1 bits (72), Expect = 3.2
Identities = 41/213 (19%), Positives = 97/213 (45%), Gaps = 13/213 (6%)
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
E+ +E + K++ L IQ+++ + + + LK + E+ ++E +
Sbjct: 2758 EQGVEYQAAMECLQKADRRSLLSEIQALHAQ---MNGRKITLKREQESEKPSQELLEYNI 2814
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN---ELKCHYQK---QLEDAVLAKLQEF 536
+KQ+Q E+ + + + L++ L +K ELK + +LE + A+ +
Sbjct: 2815 QQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHL 2874
Query: 537 QE-QLDRAEREMENDARLKENNIVDSFNKQILRIE---EQHKLEINVLEEKQREEIKLYR 592
+E + R E + + D N+ + S K+ ++ E+ K ++ EE+ +EE++ +
Sbjct: 2875 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK 2934
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHA 625
L ++ L +E Q++ E+ ++ +
Sbjct: 2935 FSLESQKQRNLQLNLLLEQQKQLLNESQQKIES 2967
Score = 32.7 bits (71), Expect = 4.2
Identities = 20/123 (16%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 373 KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE-EALEKEKF 431
++S+ ++++ + + L +++++ +++ + ++Q T+ ++ +E+++
Sbjct: 1252 RQSIHDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEHQQATELLRQAHMRQMERQRE 1311
Query: 432 AHDSTKSNITELNKRI---QSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
+ + I LN+++ S+++E L+ +ER LL+ ++ A E+ CE +N
Sbjct: 1312 DQEQLQEEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGREKLCCELRNS 1371
Query: 489 CSE 491
++
Sbjct: 1372 STQ 1374
Score = 32.3 bits (70), Expect = 5.6
Identities = 44/190 (23%), Positives = 86/190 (45%), Gaps = 12/190 (6%)
Query: 443 LNKRIQSVNDETLLLTQERD--LLKSKVNE-ERSRCAVIEQQLCEKQNQCSEVLKKCDFL 499
++ R+Q+ ++ L E L +KV + E R + ++Q + +C E L+ + L
Sbjct: 1534 ISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELR--ERL 1591
Query: 500 DNEVKTLRQ-HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI 558
E + Q +EL K E + ++QE + +DR E+E+ L +N
Sbjct: 1592 HEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQEL-----LCASNR 1646
Query: 559 VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ + +I+E+ +L ++ +E + E QL Q EKL + +V+CQ + +
Sbjct: 1647 LQELEAEQQQIQEEREL-LSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKDRD 1705
Query: 619 TAARLHAALQ 628
+ AL+
Sbjct: 1706 DLQKQVKALE 1715
>AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluronic
acid binding protein protein.
Length = 724
Score = 53.2 bits (122), Expect = 3e-06
Identities = 65/275 (23%), Positives = 120/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 147 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 206
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 207 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 266
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E+ + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 267 EILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFI 326
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 327 LEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELD 386
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 387 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 421
Score = 51.2 bits (117), Expect = 1e-05
Identities = 73/342 (21%), Positives = 146/342 (42%), Gaps = 24/342 (7%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N + Q++ + + + L ++ L + S +
Sbjct: 305 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 364
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN-------LEE------ 424
E++ E + L E+D L++ + RL KQL + K+ LEE
Sbjct: 365 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKE 424
Query: 425 -ALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
LEK AH + E + +QS+ D T + L S++ + + + ++++
Sbjct: 425 AELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA 484
Query: 483 CEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQ-KNELKCHYQKQLEDAVLAKLQEFQEQL 540
+ +V + + + + +R L+LQ K+ LK K++ + L K+ + Q QL
Sbjct: 485 AKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQL 544
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL-AQAA 599
+ E + +E + N EE +K + L E+ + K ++LQL A
Sbjct: 545 KQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRL--LYEELYNKTKPFQLQLDAFEV 602
Query: 600 EKLGLLESKVECQRR--RRGETAARL--HAALQAHWRHALRI 637
EK LL Q + + ++ A+L H L+ +H +++
Sbjct: 603 EKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKL 644
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/244 (20%), Positives = 114/244 (46%), Gaps = 15/244 (6%)
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
DK++ +L++ +++ +++LE LEK + ++ T L+ ++ +
Sbjct: 81 DKDLKILEKEIRVLLQERGAQDSRIQDLETELEKMEARLNAALREKTSLSANNATLEKQL 140
Query: 455 LLLTQERDLLKSKVNE--ERSRCAVIEQQLCEKQN----QCSEVLKKCDFLDNEVKTLRQ 508
+ LT+ +LLKSK +E + ++ +L + +N + ++ K + ++ +++ ++
Sbjct: 141 IELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQR 200
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQIL 567
LE + ++ QLE +++ +E ++ E+ +E + ++ V+ + I
Sbjct: 201 SLEESQGKI-----AQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIA 255
Query: 568 RIEEQHKL---EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLH 624
++EE K EI L++ E I + Q+ K LLE + E R E L+
Sbjct: 256 QLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLN 315
Query: 625 AALQ 628
A +Q
Sbjct: 316 AEMQ 319
Score = 38.3 bits (85), Expect = 0.085
Identities = 107/498 (21%), Positives = 196/498 (39%), Gaps = 47/498 (9%)
Query: 132 SARKLNFDKEFQPTSTPNKQQTTYNSFQPSSNKIYDRASRVLEQYKASYSKNKPGATDSY 191
S + LN DK+ T+ P + +S S K D+ ++LE+ + + GA DS
Sbjct: 50 SKQNLNVDKD---TTLPASARKVKSSESKESQK-NDKDLKILEK-EIRVLLQERGAQDSR 104
Query: 192 SASSNQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLS---ELWGDK-AERTTGYN 247
EL+ E R RE N T++ L+ L+ EL K +E N
Sbjct: 105 IQDLETELEKMEARLNAALREKTSLSANNA--TLEKQLIELTRTNELLKSKFSENGNQKN 162
Query: 248 -RGDKVDIIKLEEER--------LKREHCEAMIXXXXXXXXXXXXXXAVA----MKVDRA 294
R ++++KL +R K+E E + A + +++
Sbjct: 163 LRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKE 222
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
K S+ E L + A D+ K + EN + D+ E +
Sbjct: 223 KIDEKSET-EKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVI 281
Query: 355 TLDLAHDYQDKCKQLQNEK-------KSLEEQLNTELDNV--NVMLSNKDKEIDVLKE-N 404
D KC+ L+ EK + E LN E+ N+ +L +++E KE
Sbjct: 282 LSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQ 341
Query: 405 YDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDSTKSNITELNKRIQSVNDETLLLTQ 459
D++++ K+L+ + + +E + KEK + K + EL+K Q L+ Q
Sbjct: 342 IDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQ 401
Query: 460 ERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE---LQKNE 516
+ KS+ E + ++ + E + + + L + ++ Q LE Q
Sbjct: 402 LEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFES 461
Query: 517 LKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLE 576
K ++ED L QE+ +A + E D + + +S N++ +R+ + +
Sbjct: 462 YKALTASEIEDLKLEN-SSLQEKAAKAGKNAE-DVQ-HQILATESSNQEYVRMLLDLQTK 518
Query: 577 INVLEEKQREEIKLYRLQ 594
+ L+E + +EI + LQ
Sbjct: 519 -SALKETEIKEITVSFLQ 535
>AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.
Length = 2058
Score = 53.2 bits (122), Expect = 3e-06
Identities = 78/336 (23%), Positives = 151/336 (44%), Gaps = 43/336 (12%)
Query: 304 EAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQ 363
E L +++ L A ++ +A+ + ++E+ +V + +++ + E ++L Q
Sbjct: 51 ELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKC----Q 106
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
++ ++ +E+ EQL EL S + ID + R ++ TD + LE
Sbjct: 107 EELRERLHEESRAREQLAVEL-------SKAEGVIDGYADEKTLFERQIQEKTDIIDRLE 159
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+ L SN R+Q + E + +ER+LL + ++ +EQQL
Sbjct: 160 QEL--------LCASN------RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLL 205
Query: 484 -EKQNQCSEVLK-KC------DFLDNEVKTLRQHLELQKN---ELKCHYQKQLEDAVLAK 532
E + E L+ +C D L +VK L +E Q + EL+ +L D + +
Sbjct: 206 QETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMD-LRQQ 264
Query: 533 LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKL--EINVLEEKQREEIKL 590
Q ++QL++ + ++ A +E+ D F ++I ++E+Q K+ + E Q E++
Sbjct: 265 NQALEKQLEKMRKFLDEQAIDREHE-RDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQ 323
Query: 591 YRLQLAQAAEKLG-LLESKVECQR--RRRGETAARL 623
L + +K LL SK + QR + R E +L
Sbjct: 324 LANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL 359
Score = 47.2 bits (107), Expect = 2e-04
Identities = 75/367 (20%), Positives = 156/367 (42%), Gaps = 23/367 (6%)
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L EE RE + + + + K I +L + L +N L
Sbjct: 112 RLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQE 171
Query: 316 AEDRHRKALEK---MICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
E ++ E+ + + E + A +++ +L K L++ + LQ
Sbjct: 172 LEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQK 231
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ K+LE + ++ + K+ E+ L++ L KQL K L+E +
Sbjct: 232 QVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQA---LEKQLEKMRKFLDEQAIDREH 288
Query: 432 AHDSTKSNITELNKRIQSVNDETLLL---TQERDLLKSKVNEERSRCAVIEQQLCEKQNQ 488
D + I +L ++++ V + T+E + L + + E+ +C+ + + Q
Sbjct: 289 ERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRD 348
Query: 489 CSEVLKKCDFLDNEVKTLRQHL-----ELQKNELKCHY---QKQLEDAVLAKLQEFQEQL 540
E ++ + L+ V+ L Q L QK E + H+ + + E ++ +LQ ++ +
Sbjct: 349 IQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAI 408
Query: 541 DRAEREMEN-DARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQR-EEIKLYRLQLAQ 597
DR E+E+ N + +L++ +++ N+++ ++ Q LEI E R +E++
Sbjct: 409 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ--LEIQKKESTTRLQELEQENKLFKD 466
Query: 598 AAEKLGL 604
EKLGL
Sbjct: 467 DMEKLGL 473
Score = 45.2 bits (102), Expect = 7e-04
Identities = 73/308 (23%), Positives = 129/308 (41%), Gaps = 35/308 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKC---KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
Q + + EL D A + Q++ K + E KS Q EL+ KE+
Sbjct: 1340 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 1399
Query: 399 DV----LKENYDTVMRLNKQLTDCVKNLEE---ALEKEKF----AHDSTKSNITELNKRI 447
+ +K+ D V LN L K E ALEKEK + + K + +L +
Sbjct: 1400 EAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSL 1459
Query: 448 QSVNDETL----LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+S L LL Q++ LL + S+ + + QL E+Q + E+ L++E
Sbjct: 1460 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV---LLESEK 1516
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+R+ E + H Q Q D + +E++ K + IV+ N
Sbjct: 1517 VRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPS--EDLLKELQKQLEEKHSRIVELLN 1574
Query: 564 KQILRIEEQHKLEINVLEEKQREEIKLYR--LQLAQAA-----EKLGLLESKVECQRRRR 616
+ E++KL+ ++ ++ +++R LQ Q A +K+ L+SKVE +R+
Sbjct: 1575 E-----TEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 1629
Query: 617 GETAARLH 624
E +++
Sbjct: 1630 EEKRQQVY 1637
Score = 44.0 bits (99), Expect = 0.002
Identities = 76/344 (22%), Positives = 147/344 (42%), Gaps = 30/344 (8%)
Query: 286 AVAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKT 345
A K+ A S+L A + T + + + ++A E + C+ E R + +
Sbjct: 62 AAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQ-EELRERLHEESRAR 120
Query: 346 SHFESELYKTLDLAHDYQDKC----KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL 401
EL K + Y D+ +Q+Q EK + ++L EL + L + E +
Sbjct: 121 EQLAVELSKAEGVIDGYADEKTLFERQIQ-EKTDIIDRLEQELLCASNRLQELEAEQQQI 179
Query: 402 KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
+E + + R + + +E+ L +E + E+ + + V D+ L ++
Sbjct: 180 QEERELLSRQKEAMKAEAGPVEQQLLQET---EKLMKEKLEVQCQAEKVRDD---LQKQV 233
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ---KNELK 518
L+ V E+ SR +EQ EK + ++ ++ L+ +++ +R+ L+ Q + +
Sbjct: 234 KALEIDVEEQVSRFIELEQ---EKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER 290
Query: 519 CHYQKQLE--DAVLAKLQEFQEQLDRAEREMENDAR-LKENNIVDS---FNKQIL----- 567
+Q++++ + L + FQ + RE+E A LKE S +K+ L
Sbjct: 291 DVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 350
Query: 568 -RIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVE 610
R EE KLE V E +Q + Q + + G +E+K E
Sbjct: 351 ERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 394
Score = 43.6 bits (98), Expect = 0.002
Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 8/209 (3%)
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
TEL V EID EN + ++ ++ +L V+ L EA+ + + K T
Sbjct: 29 TELSQRLVRSGFAGTEID--PENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQT 86
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
EL + E + ++ L+ +++EE + +L + + + +
Sbjct: 87 ELMRESFRQKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFER 146
Query: 502 EVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLKENNIVD 560
+++ ++ + EL C + E +A ++QE +E L R + M+ +A E ++
Sbjct: 147 QIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQ 206
Query: 561 SFNKQILRIEEQHKLEINVLEEKQREEIK 589
K + + KLE+ EK R++++
Sbjct: 207 ETEKLM-----KEKLEVQCQAEKVRDDLQ 230
Score = 38.7 bits (86), Expect = 0.065
Identities = 52/265 (19%), Positives = 108/265 (40%), Gaps = 24/265 (9%)
Query: 331 VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNV 389
++ V D ++ + + +L T D +K + +NE + LE Q+ + +
Sbjct: 497 IQEKEVEIDQLNEQVTKLQQQLKITTD------NKVIEEKNELIRDLETQIECLMSDQEC 550
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
+ N+++EI+ L E + +L ++L + + DS K + + +
Sbjct: 551 VKRNREEEIEQLNE---VIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLA 607
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ + +E +K+ + E + + Q+L + + V K +N V H
Sbjct: 608 LEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDH 667
Query: 510 LELQKNELKC----HYQKQLEDAVLAKLQEFQE-------QLDRAEREMENDARLKENNI 558
L K EL+ K LE+ K F+E L+ ++E+ K+ +
Sbjct: 668 LSKDKPELEVVLTEDALKSLENQTYFK--SFEENGKGSIINLETRLLQLESTVSAKDLEL 725
Query: 559 VDSFNKQILRIEEQHKLEINVLEEK 583
+ KQI ++EQ + E +L++K
Sbjct: 726 TQCY-KQIKDMQEQGQFETEMLQKK 749
Score = 35.9 bits (79), Expect = 0.46
Identities = 68/306 (22%), Positives = 128/306 (41%), Gaps = 36/306 (11%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK--KSL 376
R R+++EK+ EN VA D K E E+ T +D K L+N+ KS
Sbjct: 645 RERESVEKIQSIPENSVNVAIDHLSKDKP-ELEVVLT-------EDALKSLENQTYFKSF 696
Query: 377 EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
EE + N+ L + TV + +LT C K +++ E+ +F +
Sbjct: 697 EENGKGSIINLETRLLQLES----------TVSAKDLELTQCYKQIKDMQEQGQFETEML 746
Query: 437 KSNITELNKRIQS------VNDETLLLTQE-----RDLLKSKVNEERSRCAVIEQ-QLCE 484
+ I L K ++ V+ L QE +D ER+ + Q + E
Sbjct: 747 QKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDE 806
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRA 543
+ S + + L+++V + L L+K +++ + LE + L +LQ+ E ++
Sbjct: 807 LGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKK 866
Query: 544 EREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
+RE E ++ ++ + ++ E+ N LE + E + + +LA EK
Sbjct: 867 QREKEKKRSPQDVEVLKT-TTELFHSNEESGF-FNELEALRAESVAT-KAELASYKEKAE 923
Query: 604 LLESKV 609
L+ ++
Sbjct: 924 KLQEEL 929
Score = 33.1 bits (72), Expect = 3.2
Identities = 41/213 (19%), Positives = 97/213 (45%), Gaps = 13/213 (6%)
Query: 423 EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
E+ +E + K++ L IQ+++ + + + LK + E+ ++E +
Sbjct: 1280 EQGVEYQAAMECLQKADRRSLLSEIQALHAQ---MNGRKITLKREQESEKPSQELLEYNI 1336
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN---ELKCHYQK---QLEDAVLAKLQEF 536
+KQ+Q E+ + + + L++ L +K ELK + +LE + A+ +
Sbjct: 1337 QQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHL 1396
Query: 537 QE-QLDRAEREMENDARLKENNIVDSFNKQILRIE---EQHKLEINVLEEKQREEIKLYR 592
+E + R E + + D N+ + S K+ ++ E+ K ++ EE+ +EE++ +
Sbjct: 1397 KELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLK 1456
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHA 625
L ++ L +E Q++ E+ ++ +
Sbjct: 1457 FSLESQKQRNLQLNLLLEQQKQLLNESQQKIES 1489
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 53.2 bits (122), Expect = 3e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1080 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1139
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1140 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1188
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1189 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1248
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1249 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1304
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 1305 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 1358
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/295 (22%), Positives = 132/295 (44%), Gaps = 24/295 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 480 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 539
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 540 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 595
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 596 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 655
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN-KQIL 567
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N KQ L
Sbjct: 656 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQL 715
Query: 568 RIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 716 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 770
Score = 43.6 bits (98), Expect = 0.002
Identities = 58/311 (18%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 1167 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1226
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 1227 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1286
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + ++ L
Sbjct: 1287 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQEL 1345
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 1346 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1405
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 1406 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1459
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1460 ELENELEAEQK 1470
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 624 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 683
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 684 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 743
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 744 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 803
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 804 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 862
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 863 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 920
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 921 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 975
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 761 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 817
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 818 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 877
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 878 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 937
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 938 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 995
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 996 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1055
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1056 TKHRLQ 1061
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 53.2 bits (122), Expect = 3e-06
Identities = 72/337 (21%), Positives = 157/337 (46%), Gaps = 28/337 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN-SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
++R+ A S+LR + +++ + + K K + + R V + Q+++ E
Sbjct: 1507 LERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRS--LE 1564
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQL-NTELDNVNVMLSNKDKEIDVLKENYDTV 408
EL ++ D + + + LQ+ SL+ Q+ ++E+ + L+ ++ L V
Sbjct: 1565 GELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLT-----VERLNGALAKV 1619
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
L D V+ L EAL + + +ST+ L K + + + +L + D + +
Sbjct: 1620 EESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQAL 1679
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL-ELQKNEL-------KCH 520
+E R + + + +Q+ + + +++ + + +++ LR+ L + Q+ E K
Sbjct: 1680 SEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQ 1739
Query: 521 YQKQLEDAVLAKLQEFQEQLDRAEREMENDA-RLKENNI-----VDSFNKQILRIEEQHK 574
+++L L LQ QL+ +RE+E A RL+++ + +D ++ LR H+
Sbjct: 1740 DERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR---SHE 1796
Query: 575 LEINVLEEKQREEIKL--YRLQLAQAAEKLGLLESKV 609
+ + EK R + L L+LA+A ++ LE++V
Sbjct: 1797 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQV 1833
Score = 35.9 bits (79), Expect = 0.46
Identities = 67/290 (23%), Positives = 118/290 (40%), Gaps = 20/290 (6%)
Query: 369 LQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN---LEEA 425
L EK +L L + ++K +E RL ++ D V++ +
Sbjct: 503 LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRE 562
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
LE+ + + + L K + V + T +RD+L+++ E E E
Sbjct: 563 LERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVEL 622
Query: 486 QNQCSEV-LKKCDFLDN--EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+ +++ ++ D+ ++ L + L K +L QLE+ A LQ Q Q ++
Sbjct: 623 ELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLN-RLVAQLEEEKSA-LQGRQRQAEQ 680
Query: 543 -AEREMENDARLKENNIVDSFNKQ----ILRIEEQHKLEINVLEEKQREEIKLYRLQLAQ 597
A E RL+E + +Q LR+ EQ + + R E + QLAQ
Sbjct: 681 EATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQ 740
Query: 598 AAEKLGLLESKVECQRRRRG------ETAARLHAAL-QAHWRHALRILAA 640
+ +L E ++E RR E AAR AL + H A++++AA
Sbjct: 741 LSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAA 790
Score = 35.5 bits (78), Expect = 0.60
Identities = 69/325 (21%), Positives = 137/325 (42%), Gaps = 37/325 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESE-------LYKTLDLAHDYQ 363
N L + + AL+ + E VA + Q++ E L +L +A Q
Sbjct: 658 NRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 717
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
+ +Q + QL +L ++ LS +++E++ + R + L + +
Sbjct: 718 EALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARRE---AQRQVEALERAARE-K 773
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
EAL KE H + + +++++E L E++ L+ + E + + A +E +
Sbjct: 774 EALAKE---HAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARRE 830
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHL-----------ELQKNEL---KCHYQKQLEDAV 529
+ + + +L + L E+ LRQ + EL +L + Q L +
Sbjct: 831 QLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQR 890
Query: 530 LAK---LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE-EQHKL--EINVLEEK 583
A LQ Q + + A RE+E + ++ + + + R+E E+ +L EI L+++
Sbjct: 891 AAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 950
Query: 584 QREEIKLYRLQLAQAAEKLGLLESK 608
+ E + L + QA L L ES+
Sbjct: 951 RDEGLLLAESEKQQA---LSLKESE 972
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 52.8 bits (121), Expect = 4e-06
Identities = 58/293 (19%), Positives = 129/293 (44%), Gaps = 20/293 (6%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKE 403
K++ E E+ + +D+ + + ++K LEE++ T L N + E D L +
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 404 NYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDL 463
+ +L K ++E E+ + + + +T ++++ E + +L
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAE-EEEEINAELTAKKRKLEDECSELKKDIDDLEL 962
Query: 464 LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE----- 516
+KV +E+ + L E+ E + K ++ Q +LQ E
Sbjct: 963 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 517 ---LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEE 571
K ++Q++D L + ++ + L+RA+R++E D +L + + +D N + E+
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
Query: 572 QHKLE------INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGE 618
K E I+ +E++Q EI+L + ++ + ++ L ++E +R R +
Sbjct: 1083 LEKKEFEISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASRAK 1134
Score = 48.0 bits (109), Expect = 1e-04
Identities = 62/301 (20%), Positives = 128/301 (42%), Gaps = 26/301 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK++ +EL+K ++ + D+ + L+
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L++ E+ ++ ++ K+I L+ ++ KQ+ ++ ALE+ +
Sbjct: 1504 ENKNLQQ----EISDLTEQIAEGGKQIHELE-------KIKKQVEQEKCEIQAALEEAEA 1552
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE----KQN 487
+ + + I + + V E E+D ++ +R Q + +N
Sbjct: 1553 SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRN 1612
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
V KK + NE++ H E +Y+ L+E Q LD A R
Sbjct: 1613 DALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRN-----TQGILKETQLHLDDALRGQ 1667
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
E+ LKE + +L+ E + LE+ +R K+ +L A+E++ LL +
Sbjct: 1668 ED---LKEQLAIVERRANLLQAEIEELWA--TLEQTERSR-KIAEQELLDASERVQLLHT 1721
Query: 608 K 608
+
Sbjct: 1722 Q 1722
Score = 45.6 bits (103), Expect = 6e-04
Identities = 52/287 (18%), Positives = 129/287 (44%), Gaps = 21/287 (7%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNV 389
++++ + +K+ E+++ + + +L EKK+L+E LD+
Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD--- 1012
Query: 390 MLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQS 449
L ++ ++++L + +L +Q+ D LE +LE+EK + +L ++
Sbjct: 1013 -LQAEEDKVNILTK---AKTKLEQQVDD----LEGSLEQEKKLRMDLERAKRKLEGDLKL 1064
Query: 450 VNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH 509
+ T+ + ++ L K+ ++ + + ++ ++Q ++ KK L ++ L +
Sbjct: 1065 AQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEE 1124
Query: 510 LELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRI 569
+E ++ + +KQ D + +L+E E+L+ A L + + F K +
Sbjct: 1125 IEAERAS-RAKAEKQRSD-LSRELEEISERLEEAGGATSAQVELNKKREAE-FQKLRRDL 1181
Query: 570 EE---QHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR 613
EE QH+ + L +K + + +L + + L ++ K+E ++
Sbjct: 1182 EEATLQHEAMVAALRKKHADSM----AELGEQIDNLQRVKQKLEKEK 1224
Score = 40.7 bits (91), Expect = 0.016
Identities = 59/341 (17%), Positives = 151/341 (44%), Gaps = 19/341 (5%)
Query: 302 LREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
L+E + + L ED+ KA K+ +V++ + +K E K
Sbjct: 1002 LQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1061
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
Q+ ++N+K+ L+E+L + ++ ++S + E V + + L ++ +
Sbjct: 1062 LKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL 1121
Query: 419 VKNLE----EALEKEKFAHDSTKSNITELNKRIQSVNDET---LLLTQERDLLKSKVNEE 471
+ +E + EK D ++ + E+++R++ T + L ++R+ K+ +
Sbjct: 1122 GEEIEAERASRAKAEKQRSDLSR-ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRD 1180
Query: 472 RSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA- 528
+ + + ++ + + + +DN ++ ++Q LE +K+ELK +A
Sbjct: 1181 LEEATLQHEAMVAALRKKHADSMAELGEQIDN-LQRVKQKLEKEKSELKMETDDLSSNAE 1239
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKE---NNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++K + E++ R+ + ++ + KE +++ Q R++ + L+EK
Sbjct: 1240 AISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDA 1299
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+L R + A + +++ L+ ++E + + + A L ++
Sbjct: 1300 LVSQLSRSKQA-STQQIEELKHQLEEETKAKNALAHALQSS 1339
Score = 34.7 bits (76), Expect = 1.1
Identities = 50/270 (18%), Positives = 112/270 (41%), Gaps = 24/270 (8%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
L+ Q +Q++ K LEE+ + + + S++ + D+L+E Y+ +L
Sbjct: 1304 LSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH-DCDLLREQYEEEQEGKAELQR 1362
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV 477
+ + + + ++ T+ +R + + + L Q + V ++CA
Sbjct: 1363 ALSKANSEVAQWRTKYE------TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCAS 1416
Query: 478 IEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
+E+ KQ L NEV+ L L+++++ C + + L E++
Sbjct: 1417 LEK---TKQR-----------LQNEVEDLM--LDVERSNAACAALDKKQRNFDKVLSEWK 1460
Query: 538 EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ-REEIKLYRLQLA 596
++ + + E+E + + + F + + E +LE E K ++EI Q+A
Sbjct: 1461 QKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA 1520
Query: 597 QAAEKLGLLESKVECQRRRRGETAARLHAA 626
+ +++ LE + + + E A L A
Sbjct: 1521 EGGKQIHELEKIKKQVEQEKCEIQAALEEA 1550
Score = 34.3 bits (75), Expect = 1.4
Identities = 49/248 (19%), Positives = 109/248 (43%), Gaps = 20/248 (8%)
Query: 291 VDRAKDAAISKLREAWLRLTN---SLDRAEDRHRKALEKM-ICEVENFRVV--ADDAQKK 344
V+R + +++ E W L S AE A E++ + +N ++ +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD---NVNVMLSNKDKEIDVL 401
S +SE+ + + + + ++K K+ + + E+L E D ++ M N ++ + L
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 402 KENYDTVMRL-----NKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
+ D +L KQ+ V+ LE +E E+ + + + +R++ + +
Sbjct: 1797 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQ 1856
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL--RQHL- 510
T + L+ V++ +++ ++Q E + Q + L K L +E++ R H+
Sbjct: 1857 TEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAHIA 1916
Query: 511 ELQKNELK 518
E Q N+L+
Sbjct: 1917 ESQVNKLR 1924
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 52.8 bits (121), Expect = 4e-06
Identities = 64/296 (21%), Positives = 134/296 (45%), Gaps = 26/296 (8%)
Query: 344 KTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-- 401
K++ E E+ + ++ ++ + +K LEE++ + L N + E D L
Sbjct: 57 KSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD 116
Query: 402 -KENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+E D +++ QL VK + E LE E + + +T ++++ E +
Sbjct: 117 AEERCDQLIKNKIQLEAKVKEMNERLEDE----EEMNAELTAKKRKLEDECSELKRDIDD 172
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHL--ELQKNE-- 516
+L +KV +E+ + L E+ E++ K ++ Q +LQ E
Sbjct: 173 LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK 232
Query: 517 ------LKCHYQKQLED--AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
K ++Q++D L + ++ + L+RA+R++E D +L + +I+D N + +
Sbjct: 233 VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK-QQ 291
Query: 569 IEEQHK---LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRRGE 618
+EE+ K E+N L + +E L + +L + ++ LE ++E +R R +
Sbjct: 292 LEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 347
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 657 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 716
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 717 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 765
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 766 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 825
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 826 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 881
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 882 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLADEELIETSERVQLLHSQ 935
Score = 46.4 bits (105), Expect = 3e-04
Identities = 60/311 (19%), Positives = 133/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 744 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 803
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 804 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 863
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + DE L
Sbjct: 864 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLADEEL 922
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 923 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 982
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 983 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1036
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 1037 ELENELEAEQK 1047
Score = 42.3 bits (95), Expect = 0.005
Identities = 73/336 (21%), Positives = 149/336 (44%), Gaps = 37/336 (11%)
Query: 311 NSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQ 370
N+L +A+ + + ++ + +E + V D ++ E +L T + D ++ +QL+
Sbjct: 234 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLE 293
Query: 371 N--EKKSLE-EQLNTELDNVNVM---LSNKDKE----IDVLKENYDTV----MRLNKQLT 416
+KK E LN +++ + L K KE I+ L+E + ++ K +
Sbjct: 294 ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRS 353
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
D + LEE E+ + A +T I E+NK+ E RDL ++ + E + A
Sbjct: 354 DLSRELEEISERLEEAGGATSVQI-EMNKK-----REAEFQKMRRDLEEATLQHEATAAA 407
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ---KQLEDAVLAKL 533
+ ++ V + + +DN ++ ++Q LE +K+E K +E + AK
Sbjct: 408 L-------RKKHADSVAELGEQIDN-LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 459
Query: 534 QEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
E++ R + N+ R K V+ Q +++ ++ L+EK+ +L
Sbjct: 460 N--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 517
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
R +L ++L L+ ++E + + + A L +A
Sbjct: 518 TRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 552
Score = 40.3 bits (90), Expect = 0.021
Identities = 51/306 (16%), Positives = 122/306 (39%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A ++E + + QK
Sbjct: 338 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 394
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 395 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 454
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 455 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 514
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 515 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 572
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 573 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 632
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 633 TKHRLQ 638
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 52.8 bits (121), Expect = 4e-06
Identities = 62/297 (20%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 37 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 96
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L K + L++ + + +L ++ E +LE
Sbjct: 97 ENKNLQE----EISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQSALEEAEASLE---- 148
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
H+ K +L E + ++ ++ ++K N +R ++ L + +E
Sbjct: 149 -HEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHQRV-VDSLQTSLDAETRSRNE 206
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDA 551
VL+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 207 VLRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND- 261
Query: 552 RLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 262 DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLAEQELIETSERVQLLHSQ 315
Score = 40.7 bits (91), Expect = 0.016
Identities = 49/274 (17%), Positives = 118/274 (43%), Gaps = 26/274 (9%)
Query: 313 LDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQN 371
+++A+ H++ ++ + ++ ++ + E +L + + L+H + + Q
Sbjct: 179 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANR-MAAEAQK 237
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
+ KSL+ L + + L + + D LKEN V R N L ++ L +E+ +
Sbjct: 238 QVKSLQSLLK----DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 293
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSE 491
+ + + E ++R+Q LL +Q L+ K ++ L + Q++ E
Sbjct: 294 SRKLAEQELIETSERVQ------LLHSQNTSLINQKKK--------MDADLSQLQSEVEE 339
Query: 492 VLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDA 551
+++C + + K + ELK E A L+ ++ +++ +++++
Sbjct: 340 AVQECRNAEEKAKKAITDAAMMAEELK------KEQDTSAHLERMKKNMEQTIKDLQHRL 393
Query: 552 RLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
E + KQ+ ++E + + LE +Q+
Sbjct: 394 DEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 427
>BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix
protein p110 protein.
Length = 364
Score = 52.8 bits (121), Expect = 4e-06
Identities = 67/329 (20%), Positives = 142/329 (43%), Gaps = 24/329 (7%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT 355
D A++ L EA ++R +++ + + + E+E+FR D ++K + ++EL +
Sbjct: 51 DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEK 110
Query: 356 LDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D ++ L S + +++L ++ + + K +E L+ + + +QL
Sbjct: 111 ESSLIDLKEHASSL----ASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ---LKKQAEQL 163
Query: 416 TDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ + N +E + + I +L+K DE E D L + E
Sbjct: 164 FNQMYNPAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKE----- 218
Query: 476 AVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLR--QHLELQKNELKCHYQKQLEDAVLAKL 533
+E + +K + +E+ + + +V L+ Q LE +KN ++ ED++
Sbjct: 219 --VENEKNDKDKKIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNS 276
Query: 534 QEFQ-EQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
Q Q E+L A + + + + + +Q L +E H + + KQ EEI +
Sbjct: 277 QHLQIEELMNALEKTRQELDATKARLAST--QQSLAEKEAHLANLRIERRKQLEEILEMK 334
Query: 593 LQ--LAQAAEK---LGLLESKVECQRRRR 616
+ LA +EK + LLE +++++
Sbjct: 335 QEALLAAISEKDANIALLELSASKKKKKK 363
Score = 47.2 bits (107), Expect = 2e-04
Identities = 41/188 (21%), Positives = 84/188 (44%), Gaps = 10/188 (5%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
K + K+ L +++N+ L +KDK++ LK+ ++ + + LEEAL
Sbjct: 2 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAL 61
Query: 427 -EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEK 485
EKE+ + + +R++ + +E LK KVN ++ E L +
Sbjct: 62 SEKERIIERLKEQRERDDRERLEEIES----FRKENKDLKEKVNALQAELTEKESSLIDL 117
Query: 486 QNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER 545
+ S + D+++K+L +E +K E C +LE + + ++ Q+
Sbjct: 118 KEHASSLASAGLKRDSKLKSLEIAIEQKKEE--C---SKLEAQLKKQAEQLFNQMYNPAH 172
Query: 546 EMENDARL 553
+E+D+R+
Sbjct: 173 NIEDDSRM 180
Score = 39.9 bits (89), Expect = 0.028
Identities = 68/303 (22%), Positives = 131/303 (43%), Gaps = 39/303 (12%)
Query: 354 KTLDLAHDYQDKCKQLQNEK---KSLE---EQLNTELDNVNVMLSNKDKEIDVLKEN--- 404
K +L +DK KQL N K KSL+ +T L + LS K++ I+ LKE
Sbjct: 18 KIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER 77
Query: 405 --------YDTVMRLNKQLTDCVKNLE-EALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
++ + NK L + V L+ E EKE S++ +L + S+ L
Sbjct: 78 DDRERLEEIESFRKENKDLKEKVNALQAELTEKE--------SSLIDLKEHASSLASAGL 129
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC-SEVLKKCDFLDNEVKTLRQHL-ELQ 513
+ L+ + +++ C+ +E QL ++ Q +++ ++++ + + +++
Sbjct: 130 KRDSKLKSLEIAIEQKKEECSKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADQIK 189
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM-ENDARLKE-NNIVDSFNKQILRIEE 571
+ + + Y + A++ E L E E + D ++ E + NK++ ++
Sbjct: 190 QLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELERHMKDQNKKVANLKH 249
Query: 572 QHKLE----INVLEE-KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+LE +LEE ++RE+ Q Q E + LE R+ T ARL +
Sbjct: 250 NQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEK----TRQELDATKARLAST 305
Query: 627 LQA 629
Q+
Sbjct: 306 QQS 308
>BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for
IMAGE:3997460) protein.
Length = 512
Score = 52.8 bits (121), Expect = 4e-06
Identities = 65/275 (23%), Positives = 120/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 132 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 191
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 192 GKIAQLEGKLVSIEKEEIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 251
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E+ + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 252 EILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFI 311
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 312 LEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELD 371
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 372 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 406
Score = 42.7 bits (96), Expect = 0.004
Identities = 58/275 (21%), Positives = 126/275 (45%), Gaps = 21/275 (7%)
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC-VKNLE 423
K ++ + +K+S ++ LN + D + K K E+ V+ + D +++LE
Sbjct: 40 KSQRFKQQKES-KQNLNVDKDTTLPASARKVKS----SESKIRVLLQERGAQDRRIQDLE 94
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNE--ERSRCAVIEQQ 481
LEK + ++ T L+ ++ + + LT+ +LLKSK +E + ++ +
Sbjct: 95 TELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLE 154
Query: 482 LCEKQN----QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQ 537
L + +N + ++ K + ++ +++ ++ LE + ++ QLE +++ +E
Sbjct: 155 LMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-----AQLEGKLVSIEKEEI 209
Query: 538 EQLDRAEREMENDARLK-ENNIVDSFNKQILRIEEQHKL---EINVLEEKQREEIKLYRL 593
++ E+ +E + ++ V+ + I ++EE K EI L++ E I +
Sbjct: 210 DEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSK 269
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
Q+ K LLE + E R E L+A +Q
Sbjct: 270 QVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQ 304
Score = 39.9 bits (89), Expect = 0.028
Identities = 41/199 (20%), Positives = 90/199 (45%), Gaps = 11/199 (5%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAH 360
KL++ L++ +SL + E +L + +C + ++ K+ + FE EL +TLD
Sbjct: 319 KLQQKELQI-DSLLQQEKELSSSLHQKLCSFQ------EEMVKEKNLFEEELKQTLDELD 371
Query: 361 DYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSN-KDKEIDVLKE---NYDTVMRLNKQLT 416
Q K +Q + K LEE+ + + + ++ K KE ++ K + + L ++
Sbjct: 372 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYD 431
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
V++LE+ + + T S I +L S+ ++ + + ++ ++ S
Sbjct: 432 SMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQ 491
Query: 477 VIEQQLCEKQNQCSEVLKK 495
+ L + Q + ++ KK
Sbjct: 492 EYVRMLLDLQTKSAKKKKK 510
Score = 38.7 bits (86), Expect = 0.065
Identities = 33/153 (21%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N + Q++ + + + L ++ L + S +
Sbjct: 290 NRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 349
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
E++ E + L E+D L++ + RL KQL + K+ E L K + K
Sbjct: 350 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEEL---KLLEEKLK 406
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNE 470
EL K + TLLL ++ D + + +
Sbjct: 407 GKEAELEKSSAAHTQATLLLQEKYDSMVQSLED 439
Score = 37.1 bits (82), Expect = 0.20
Identities = 50/236 (21%), Positives = 94/236 (39%), Gaps = 19/236 (8%)
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-------KSLEEQLNTEL 384
EN + D+ E + D KC+ L+ EK + E LN E+
Sbjct: 244 ENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEM 303
Query: 385 DNV--NVMLSNKDKEIDVLKE-NYDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDST 436
N+ +L +++E KE D++++ K+L+ + + +E + KEK +
Sbjct: 304 QNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEEL 363
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC 496
K + EL+K Q L+ Q + KS+ E + ++ + E + + +
Sbjct: 364 KQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQAT 423
Query: 497 DFLDNEVKTLRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN 549
L + ++ Q LE Q K ++ED L QE+ +A + E+
Sbjct: 424 LLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN-SSLQEKAAKAGKNAED 478
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 52.8 bits (121), Expect = 4e-06
Identities = 55/258 (21%), Positives = 120/258 (46%), Gaps = 12/258 (4%)
Query: 351 ELYKTLDLAHDYQDKCKQLQN-EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+L L HD D K+ ++ EK +L E+L ++ +L K+ D+L++ +
Sbjct: 12 DLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELT 71
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
L L + V + ++ ++K K +D + + L + ++ +L + +
Sbjct: 72 ALKGALKEEVSSHDQEMDKLKEQYD---AELQALRESVEEATKNVEVLASRSNTSEQDQA 128
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ---KQLE 526
R +++++ + Q + E+ ++ L +++ L+ K LK Y+ +QLE
Sbjct: 129 GTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLK-KYEGEIRQLE 187
Query: 527 DAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQR- 585
+A++ +E +E + A R +EN+ + N+ + +Q ++ E+ K E E+ +R
Sbjct: 188 EALVHVRKEEKEAVS-ARRALENELEAAQGNLSQTTQEQ-KQLSEKLKEESEQKEQLRRL 245
Query: 586 -EEIKLYRLQLAQAAEKL 602
E++ R L + EKL
Sbjct: 246 KNEMENERWHLGKTIEKL 263
Score = 50.8 bits (116), Expect = 1e-05
Identities = 66/325 (20%), Positives = 142/325 (43%), Gaps = 43/325 (13%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFE 349
K+ + + R + L L N LD ++++R+ L +M +++ + A+ ++ +
Sbjct: 262 KLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQ 321
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+ + DYQ + +++ LE+ L + + E++ D
Sbjct: 322 DGMRLMEEELRDYQRAQDEALTKRQLLEQTLK-----------DLEYELEAKSHLKDDRS 370
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
RL KQ+ D V LE LE+E+ D I+ ++++ + +E LL+ +
Sbjct: 371 RLVKQMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLRNE---------LLQERAA 421
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAV 529
+ C I E+QN+ ++K+ HLE K Q+E
Sbjct: 422 RQDLECDKIS---LERQNK-------------DLKSRIIHLEGSYRSSKEGLVVQME--- 462
Query: 530 LAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIK 589
A++ E +++L+ ER+ N +L + + +++++++H L + +++ +K
Sbjct: 463 -ARIAELEDRLESEERDRAN-LQLSNRRLERKVKELVMQVDDEH-LSLTDQKDQLSLRLK 519
Query: 590 LYRLQLAQAAEKLGLLE-SKVECQR 613
+ Q+ +A E++ LE SK + QR
Sbjct: 520 AMKRQVEEAEEEIDRLESSKKKLQR 544
Score = 47.2 bits (107), Expect = 2e-04
Identities = 51/261 (19%), Positives = 119/261 (45%), Gaps = 17/261 (6%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVL-------KENYDTVMRLNKQLTDCV 419
+Q Q E + L++QL+ D ++ ++D+E L K++ ++ + D +
Sbjct: 4 EQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLL 63
Query: 420 KN-------LEEALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEE 471
+ L+ AL++E +HD + E + +Q++ + T+ ++L S+ N
Sbjct: 64 RKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTS 123
Query: 472 RSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCHYQKQLEDAVL 530
A E ++ Q + ++ + + L+ V L++ +E L+ +E K + + +
Sbjct: 124 EQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEI 183
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEE-KQREEIK 589
+L+E + + E+E + R EN + + +EQ +L + EE +Q+E+++
Sbjct: 184 RQLEEALVHVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLR 243
Query: 590 LYRLQLAQAAEKLGLLESKVE 610
+ ++ LG K++
Sbjct: 244 RLKNEMENERWHLGKTIEKLQ 264
Score = 44.0 bits (99), Expect = 0.002
Identities = 74/338 (21%), Positives = 145/338 (42%), Gaps = 27/338 (7%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESEL 352
R ++ ++ L+ A +S D+ D K E+ E++ R ++A K S
Sbjct: 64 RKRERELTALKGALKEEVSSHDQEMD---KLKEQYDAELQALRESVEEATKNVEVLASRS 120
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+ + + K LQ E + L+ + + EL+ ++ ++I+ LK +
Sbjct: 121 NTSEQDQAGTEMRVKLLQEENEKLQGR-SEELER---RVAQLQRQIEDLKGDEAKAKETL 176
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+ ++ LEEAL + S L +++ TQE+ L K+ EE
Sbjct: 177 KKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEES 236
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTL-----RQHLELQKNELKCHYQKQLED 527
+ + + E +N+ + K + L E+ + LELQ N+L + +K +
Sbjct: 237 EQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQ-NQLDEYKEKNRRE 295
Query: 528 AVLAKLQ-EFQEQLDRAER------EMENDARLKENNIVDSFNKQILRIEEQHKLEINV- 579
LA++Q + +E+ AE+ +M++ RL E + D Q + ++ LE +
Sbjct: 296 --LAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLK 353
Query: 580 ---LEEKQREEIKLYRLQLA-QAAEKLGLLESKVECQR 613
E + + +K R +L Q +K+ LE ++E +R
Sbjct: 354 DLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEER 391
>AF179308-1|AAD51855.1| 1232|Homo sapiens KIF4 protein.
Length = 1232
Score = 52.8 bits (121), Expect = 4e-06
Identities = 81/405 (20%), Positives = 172/405 (42%), Gaps = 30/405 (7%)
Query: 196 NQELKLPEMRPFGENRESLKFIQNKYIDTIDSDLLSLSELWGDKAERTTGYNRGDKVDII 255
N++ KL +++ E+ E N+ I + + + L + AE+ + + ++I
Sbjct: 617 NEQSKLLKLK---ESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKRDKEVI 673
Query: 256 KLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVDRAKDAAISKLREAWLRLTNSLDR 315
+L+E KR++ + K + A AA +L++A + D+
Sbjct: 674 QLKERDRKRQY-----ELLKLERNFQKQSNVLRRKTEEAA-AANKRLKDALQKQREVADK 727
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKS 375
++ + +E V+N+ + T + L L+ QL+ +K+S
Sbjct: 728 RKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKES 787
Query: 376 LEE------QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK-QLTDCVKNLEEALEK 428
E + L V +S + I E+ +T M Q+ D + L +A +
Sbjct: 788 GENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESE 847
Query: 429 EKFAHD-STKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQN 487
++ + I E ++ + E + + L+S + + ++ CA +++ L E++N
Sbjct: 848 DRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERN 907
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLE-----LQKNELKCHYQKQLEDAVLAKLQEFQEQLDR 542
+E+ + + V+ +QH E L + + +KQLE++V K Q+ Q L
Sbjct: 908 HFAEI--ETELQAELVRMEQQHPEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLQSTLKC 965
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
+ E+E +++E V N+Q+LR E K ++ +L+ R++
Sbjct: 966 QDEELE---KMRE---VCEQNQQLLRENEIIKQKLTLLQVASRQK 1004
Score = 50.4 bits (115), Expect = 2e-05
Identities = 79/330 (23%), Positives = 155/330 (46%), Gaps = 39/330 (11%)
Query: 322 KALEKMICEVENFRVVAD---DAQKKTSHFES-ELYKTLDLAHDYQDKCKQLQNEKKS-L 376
+A EKM ++E R A D QK E EL + +++ + Q QL +E + +
Sbjct: 425 QANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACM 484
Query: 377 EEQLNTELDNVNVMLSNKD--KEIDVLKENYDTVM-RLNKQLTDCVKNL--EEALEKEKF 431
++T ++ + ++ + + D + +++K+L + K L +EAL ++
Sbjct: 485 AAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMT 544
Query: 432 AHDST--------KSNITELNKRI---QSVNDETLL--LTQERDLLKSKVNEER-SRCAV 477
+DS + NI EL + Q +E +L T ++D ++K++E R R
Sbjct: 545 QNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQE 604
Query: 478 IEQQLCE---KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
+E Q+ + K N+ S++LK + + V L Q + + KN+ ++ EDA +
Sbjct: 605 LEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDA-----E 659
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
+F++ + ++E+ +LKE + + ++L++E + + NVL K EE +
Sbjct: 660 KFRQWKQKRDKEV---IQLKERDRKRQY--ELLKLERNFQKQSNVLRRK-TEEAAAANKR 713
Query: 595 LAQAAEK-LGLLESKVECQRRRRGETAARL 623
L A +K + + + E Q R TAAR+
Sbjct: 714 LKDALQKQREVADKRKETQSRGMEGTAARV 743
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 49 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 108
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 109 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 157
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 158 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 217
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 218 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 273
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 274 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLADRELIETSERVQLLHSQ 327
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/311 (18%), Positives = 132/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 136 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 195
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 196 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 255
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + D L
Sbjct: 256 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLADREL 314
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 315 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 374
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 375 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 428
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 429 ELENELEAEQK 439
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 117 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 176
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 177 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 225
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 226 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 285
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 286 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 341
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 342 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLADRELIETSERVQLLHSQ 395
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/311 (18%), Positives = 132/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 204 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 263
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 264 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 323
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + D L
Sbjct: 324 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLADREL 382
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 383 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 442
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 443 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 496
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 497 ELENELEAEQK 507
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/298 (21%), Positives = 128/298 (42%), Gaps = 20/298 (6%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 49 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 108
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 109 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 157
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 158 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 217
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 218 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 273
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN + +L+ E + E+ + E+ KL +L + +E++ LL S+
Sbjct: 274 -DLKENIAIVERRNNLLQAELE---ELRAVVEQTERSRKLADRELIETSERVQLLHSQ 327
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/311 (18%), Positives = 132/311 (42%), Gaps = 22/311 (7%)
Query: 290 KVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKA---LEKMICEVENFRVVADDAQKKTS 346
KV + +A +L+ A SL+ E + +A ++ E+E D+ ++
Sbjct: 136 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 195
Query: 347 HFESELYKTLDLAHDYQDKCK-QLQNEKKSLEEQLNT---ELDNVNVMLSNKDKEI---- 398
+ +L + D + + + + KK +E LN +L + N M + K++
Sbjct: 196 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 255
Query: 399 DVLKENY---DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETL 455
+LK+ D +R N L + + +E + + ++ + E +R + + D L
Sbjct: 256 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLADREL 314
Query: 456 LLTQER-DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQK 514
+ T ER LL S+ ++ ++ L + Q + E +++C + + K +
Sbjct: 315 IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 374
Query: 515 NELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHK 574
ELK E A L+ ++ +++ +++++ E + KQ+ ++E + +
Sbjct: 375 EELK------KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 428
Query: 575 LEINVLEEKQR 585
N LE +Q+
Sbjct: 429 ELENELEAEQK 439
>BC115701-1|AAI15702.1| 828|Homo sapiens SLMAP protein protein.
Length = 828
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/294 (21%), Positives = 131/294 (44%), Gaps = 22/294 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQ----NEKKSLEEQLNTELDNVNVMLSNKD 395
+A+++ H EL + +LA + KC +LQ E+K+ Q+ + V+ +
Sbjct: 494 EAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQ 553
Query: 396 K-EIDV--LKENYDTVMRLNK----QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ ID L+E D+ + + D + L +A K D+ +++ E K+++
Sbjct: 554 RLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVR 613
Query: 449 SVNDETLLLTQERDL-LKSKVNEERSRCAVIEQQLCEK----QNQCSEVLKKCDFLDNEV 503
+ + E + + S N + RC E Q E+ Q + ++ K+ + L+ E
Sbjct: 614 AELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETEC 673
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ--LDRAEREMEND-ARLKENNIVD 560
+L++ L +EL+ +K+L ++ L+ + L + +E+EN LKE ++ D
Sbjct: 674 HSLKRENVLLSSELQ-RQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD 732
Query: 561 SFN-KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQA-AEKLGLLESKVECQ 612
S + K +L E ++ EK + + +L+ EK + + +C+
Sbjct: 733 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCK 786
Score = 44.0 bits (99), Expect = 0.002
Identities = 85/434 (19%), Positives = 177/434 (40%), Gaps = 47/434 (10%)
Query: 195 SNQELKLPEMRPFGEN-RESLKFIQNKYIDTIDS--DLLSLSELWGDKAERTTGYNRGDK 251
SN E + ++ E +E L+ + NKY ++ DL ++ K E + +K
Sbjct: 280 SNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKGQAEK 339
Query: 252 VDII-KLEEERLKREHCEAMIXXXXXXXXXXXXX-XAVAMKVDRAKDAAISKLREAWLRL 309
++ K++E K + +A I A+ ++++ ++ + + L
Sbjct: 340 KELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSLEHLL 399
Query: 310 TNSLDRAEDRHR--KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCK 367
+ S H+ + +K+I E + V + K + ++ D ++K
Sbjct: 400 SKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSS 459
Query: 368 QLQNEKKSLEEQLNTELDNVNVM---LSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
+ + E+ LN L V+++ L EI+ +E + L K+L
Sbjct: 460 DDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQE----IQHLRKEL--------- 506
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
+E ++ A S K EL LL +ER +++V E + V++ QL +
Sbjct: 507 -IEAQELARTS-KQKCFELQA----------LLEEERKAYRNQVEESTKQIQVLQAQL-Q 553
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AKLQEFQEQLDR 542
+ + +E L+ + D+E+ + R L ++E+ +Q + A + QE+L +
Sbjct: 554 RLHIDTENLR--EEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKK 611
Query: 543 AEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
E+E + + K+I ++ +L E++QREE + +L + ++
Sbjct: 612 VRAELE-----RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEW 666
Query: 603 GLLESKVECQRRRR 616
LE+ EC +R
Sbjct: 667 NALET--ECHSLKR 678
Score = 35.1 bits (77), Expect = 0.80
Identities = 75/336 (22%), Positives = 139/336 (41%), Gaps = 39/336 (11%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT--ELDNV 387
EV ++ A + EL + H+Y+ K ++ ++ L+E++ +L V
Sbjct: 218 EVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAK--ESLRRVLQEKIEVVRKLSEV 275
Query: 388 NVMLSNKDKEIDVLKE-NYDTVMRL----NK------QLTDCVKNLEEALEKEKFAHDST 436
LSN + E LKE N T L NK ++ D L+ A K++
Sbjct: 276 ERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKG 335
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSK---VNEERSRCAVIEQQLCEKQ-NQCSEV 492
++ EL +I + ++ L + + L++ NE + V + L EK +CS +
Sbjct: 336 QAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQVRLEHLQEKTLKECSSL 395
Query: 493 LKKCDFLDNEVKTLRQHLELQKNEL-KCHYQKQLEDAVL-------AKLQEFQEQLDRAE 544
+ + Q +E QK + + H K +E+ L AK +F + L ++
Sbjct: 396 EHLLSKSGGDCTFIHQFIECQKKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSK 455
Query: 545 REMEN---DARLKENNIVDSFNK--------QILRIEEQHKLEINVLEEKQREEIKLYRL 593
+ + DA++ E ++ + K Q + E + K EI L ++ E +L R
Sbjct: 456 EKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELART 515
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQA 629
+ E LLE + + R + E+ ++ LQA
Sbjct: 516 SKQKCFELQALLEEERKAYRNQVEESTKQIQ-VLQA 550
>BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein.
Length = 790
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/294 (21%), Positives = 131/294 (44%), Gaps = 22/294 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQ----NEKKSLEEQLNTELDNVNVMLSNKD 395
+A+++ H EL + +LA + KC +LQ E+K+ Q+ + V+ +
Sbjct: 456 EAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQ 515
Query: 396 K-EIDV--LKENYDTVMRLNK----QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ ID L+E D+ + + D + L +A K D+ +++ E K+++
Sbjct: 516 RLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVR 575
Query: 449 SVNDETLLLTQERDL-LKSKVNEERSRCAVIEQQLCEK----QNQCSEVLKKCDFLDNEV 503
+ + E + + S N + RC E Q E+ Q + ++ K+ + L+ E
Sbjct: 576 AELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETEC 635
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ--LDRAEREMEND-ARLKENNIVD 560
+L++ L +EL+ +K+L ++ L+ + L + +E+EN LKE ++ D
Sbjct: 636 HSLKRENVLLSSELQ-RQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD 694
Query: 561 SFN-KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQA-AEKLGLLESKVECQ 612
S + K +L E ++ EK + + +L+ EK + + +C+
Sbjct: 695 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCK 748
Score = 44.4 bits (100), Expect = 0.001
Identities = 62/334 (18%), Positives = 142/334 (42%), Gaps = 20/334 (5%)
Query: 289 MKVDRAKDAAISKLREAWLR-LTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSH 347
+KV K I + +A + L + +D E++ ++ K +E + D ++ +
Sbjct: 321 LKVAEGKQEEIQQKGQAEKKELQHKIDEMEEKEQELQAK----IEALQADNDFTNERLTA 376
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
+ +L L ++ +N+ ++ E + L S+ + + +++ +
Sbjct: 377 LQEKLIVEGHLTKAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNE 436
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT--ELNKRI-QSVNDETLLLTQERDLL 464
+ L D ++ + +E ++ K I EL + Q + LL +ER
Sbjct: 437 PLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAY 496
Query: 465 KSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQ 524
+++V E + V++ QL ++ + +E L+ + D+E+ + R L ++E+ +Q
Sbjct: 497 RNQVEESTKQIQVLQAQL-QRLHIDTENLR--EEKDSEITSTRDELLSARDEILLLHQAA 553
Query: 525 LEDAVL--AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEE 582
+ A + QE+L + E+E + + K+I ++ +L E+
Sbjct: 554 AKVASERDTDIASLQEELKKVRAELE-----RWRKAASEYEKEITSLQNSFQLRCQQCED 608
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+QREE + +L + ++ LE+ EC +R
Sbjct: 609 QQREEATRLQGELEKLRKEWNALET--ECHSLKR 640
Score = 41.5 bits (93), Expect = 0.009
Identities = 66/311 (21%), Positives = 135/311 (43%), Gaps = 43/311 (13%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT--ELDNV 387
EV ++ A + EL + H+Y+ K ++ ++ L+E++ +L V
Sbjct: 218 EVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAK--ESLRRVLQEKIEVVRKLSEV 275
Query: 388 NVMLSNKDKEIDVLKE--------------NYDTVMRLNKQLTDCVKNLE---EAL---- 426
LSN + E LKE Y+ + K L+D +K E E +
Sbjct: 276 ERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKG 335
Query: 427 --EKEKFAH--DSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
EK++ H D + EL +I+++ + + L+ K+ E +E+
Sbjct: 336 QAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEKLIVEGHLTKAVEETK 395
Query: 483 CEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE-LKCHYQKQLEDAVLAKLQEFQEQLD 541
K+NQ K+ DF D TL E ++ +Q + LAK+ ++ L
Sbjct: 396 LSKENQTR--AKESDFSD----TLSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQ 449
Query: 542 RAEREMENDARLK--ENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
A+ E+E ++ ++++ +++ R +Q E+ L E++R K YR Q+ ++
Sbjct: 450 GAQSEIEAKQEIQHLRKELIEA--QELARTSKQKCFELQALLEEER---KAYRNQVEEST 504
Query: 600 EKLGLLESKVE 610
+++ +L+++++
Sbjct: 505 KQIQVLQAQLQ 515
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 52.4 bits (120), Expect = 5e-06
Identities = 61/328 (18%), Positives = 137/328 (41%), Gaps = 12/328 (3%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D++++ L KM E+ + + D + K H S+L LD +K E + L+
Sbjct: 620 DQYKEELSKMEKEIMHLK---RDGENKAMHL-SQLDMILDQTKTELEKKTNAVKELEKLQ 675
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
TEL + E+ + +R ++L D ++ + +LE++
Sbjct: 676 HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLT 735
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
+ + E I+ E L + Q ++ + ++ ++ + E + + + + K +
Sbjct: 736 AELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE 795
Query: 498 FL----DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN-DAR 552
+ E+K + +E ++L+ + ++QL + LQ QE + + ++E+E R
Sbjct: 796 GTLEKSELELKECNKQIESLNDKLQ-NAKEQLREKEFIMLQNEQE-ISQLKKEIERTQQR 853
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
+KE V +Q + + + +++ RE+++ +LA+A + + ++E +
Sbjct: 854 MKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIE-R 912
Query: 613 RRRRGETAARLHAALQAHWRHALRILAA 640
E +L AH H L A
Sbjct: 913 LSSELEDMKQLSKEKDAHGNHLAEELGA 940
Score = 42.3 bits (95), Expect = 0.005
Identities = 67/280 (23%), Positives = 129/280 (46%), Gaps = 32/280 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDV 400
++K + S K +L + +K NEK +SLE +NTE + + + K K+I
Sbjct: 334 EEKIVAYSSIAAKNAELEQELMEK-----NEKIRSLETNINTEHEKI-CLAFEKAKKIH- 386
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +K++ ++ LE LEK+ + ++ L + I + + L + +
Sbjct: 387 --------LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI--ICKQHHLESLD 436
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
R L +SK E + ++ L QNQ SE K LD+ ++ ++ L L N+L+ +
Sbjct: 437 RLLTESK-GEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN 495
Query: 521 YQKQLEDAVLAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+K E + K +E Q++L ++ + ++N I+ +Q ++ +Q +
Sbjct: 496 KEK-FEKQLKKKSEEVYCLQKELKIKNHSLQETS--EQNVILQHTLQQQQQMLQQETIRN 552
Query: 578 NVLEEKQRE-EIKLYRL------QLAQAAEKLGLLESKVE 610
LE+ Q + E ++ +L Q +AEKL +E K E
Sbjct: 553 GELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 592
Score = 41.5 bits (93), Expect = 0.009
Identities = 77/393 (19%), Positives = 160/393 (40%), Gaps = 36/393 (9%)
Query: 233 SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVD 292
++L K TG R K+++ + +EE K E + ++ + M +D
Sbjct: 598 ADLKRQKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHLSQLDMILD 655
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVADDAQKKTSHFE 349
+ K + K A L E +AL+K + E++N ++
Sbjct: 656 QTK-TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELR 714
Query: 350 SELYKT-LDLAHDY---QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENY 405
L K L L Y +D +L+ K +E++ EL ++ L ++ E LK+
Sbjct: 715 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDK-KQELLEMDQALKERNWE---LKQRA 770
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------------E 453
V L+ + + +E+ + K + + ++ + E NK+I+S+ND E
Sbjct: 771 AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 830
Query: 454 TLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
++L E+++ LK ++ + R +E + E++ + K+ L E++ R+ ++
Sbjct: 831 FIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQ 890
Query: 512 LQKNEL-KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR-- 568
EL + +Q+ + +L E D + E DA N++ + +R
Sbjct: 891 NSHTELAEARHQQVQAQREIERLS--SELEDMKQLSKEKDAH--GNHLAEELGASKVREA 946
Query: 569 -IEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
+E + + EI L + + Y +++ E
Sbjct: 947 HLEARMQAEIKKLSAEVESLKEAYHMEMISHQE 979
Score = 40.7 bits (91), Expect = 0.016
Identities = 57/269 (21%), Positives = 123/269 (45%), Gaps = 20/269 (7%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+++D+A +L++ ++T+ LD HR +E+ I ++E ++ K+ +
Sbjct: 753 LEMDQALKERNWELKQRAAQVTH-LDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQ 811
Query: 349 ESELYKTLDLAHDY--QDKCKQLQNEKK--SLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
L L A + + + LQNE++ L++++ + M S ++ +
Sbjct: 812 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 871
Query: 405 YDTVMRLNKQLT---DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
Y + L ++L + V+N L + + + I L+ ++ + L++E+
Sbjct: 872 YKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQ----LSKEK 927
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ--HLELQKNELKC 519
D + + EE V E L E + Q +KK L EV++L++ H+E+ ++
Sbjct: 928 DAHGNHLAEELGASKVREAHL-EARMQAE--IKK---LSAEVESLKEAYHMEMISHQENH 981
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREME 548
K D+ + +Q+ EQL++A+ E+E
Sbjct: 982 AKWKISADSQKSSVQQLNEQLEKAKLELE 1010
Score = 39.1 bits (87), Expect = 0.049
Identities = 67/283 (23%), Positives = 126/283 (44%), Gaps = 35/283 (12%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQL---------NTELDNVNVMLSNKDKEIDVLKENYDTV 408
L + KC QL +K LEE++ N EL+ L K+++I L+ N +T
Sbjct: 315 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQ---ELMEKNEKIRSLETNINTE 371
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKS 466
+ K + LE+ K + +L K+ Q ++ T+ + Q+ + K
Sbjct: 372 HEKICLAFEKAKKIH--LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQ 429
Query: 467 KVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHY 521
E R + +K+N + E LK +E V+ L LE+ K EL H
Sbjct: 430 HHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 489
Query: 522 QKQLEDAVLAKLQEFQEQLDRAERE---MENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
QLE ++F++QL + E ++ + ++K +++ ++ + ++ QH L+
Sbjct: 490 -NQLE----GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL---QHTLQ-Q 540
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAA 621
+ Q+E I+ L+ Q KL SK+E + +++ E++A
Sbjct: 541 QQQMLQQETIRNGELEDTQT--KLEKQVSKLEQELQKQRESSA 581
Score = 33.9 bits (74), Expect = 1.8
Identities = 28/131 (21%), Positives = 59/131 (45%), Gaps = 1/131 (0%)
Query: 420 KNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
K + E LEK + + + N+T K + + + L E ++LK K+ + + +
Sbjct: 2 KKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGK 61
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQE 538
++L + SEV+ + + L LE + L+ + E+ L ++ E
Sbjct: 62 EKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNE 121
Query: 539 QLDRAEREMEN 549
+LD ++E+E+
Sbjct: 122 RLDLCQQEIES 132
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 52.4 bits (120), Expect = 5e-06
Identities = 61/328 (18%), Positives = 137/328 (41%), Gaps = 12/328 (3%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
D++++ L KM E+ + + D + K H S+L LD +K E + L+
Sbjct: 874 DQYKEELSKMEKEIMHLK---RDGENKAMHL-SQLDMILDQTKTELEKKTNAVKELEKLQ 929
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK 437
TEL + E+ + +R ++L D ++ + +LE++
Sbjct: 930 HSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLT 989
Query: 438 SNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCD 497
+ + E I+ E L + Q ++ + ++ ++ + E + + + + K +
Sbjct: 990 AELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE 1049
Query: 498 FL----DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN-DAR 552
+ E+K + +E ++L+ + ++QL + LQ QE + + ++E+E R
Sbjct: 1050 GTLEKSELELKECNKQIESLNDKLQ-NAKEQLREKEFIMLQNEQE-ISQLKKEIERTQQR 1107
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
+KE V +Q + + + +++ RE+++ +LA+A + + ++E +
Sbjct: 1108 MKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIE-R 1166
Query: 613 RRRRGETAARLHAALQAHWRHALRILAA 640
E +L AH H L A
Sbjct: 1167 LSSELEDMKQLSKEKDAHGNHLAEELGA 1194
Score = 43.6 bits (98), Expect = 0.002
Identities = 67/320 (20%), Positives = 147/320 (45%), Gaps = 30/320 (9%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
+++D+A +L++ ++T+ LD HR +E+ I ++E ++ K+ +
Sbjct: 1007 LEMDQALKERNWELKQRAAQVTH-LDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQ 1065
Query: 349 ESELYKTLDLAHDY--QDKCKQLQNEKK--SLEEQLNTELDNVNVMLSNKDKEIDVLKEN 404
L L A + + + LQNE++ L++++ + M S ++ +
Sbjct: 1066 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 1125
Query: 405 YDTVMRLNKQLT---DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER 461
Y + L ++L + V+N L + + + I L+ ++ + L++E+
Sbjct: 1126 YKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQ----LSKEK 1181
Query: 462 DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ--HLELQKNELKC 519
D + + EE V E L E + Q +KK L EV++L++ H+E+ ++
Sbjct: 1182 DAHGNHLAEELGASKVREAHL-EARMQAE--IKK---LSAEVESLKEAYHMEMISHQENH 1235
Query: 520 HYQKQLEDAVLAKLQEFQEQLDRAEREMEND----ARLKE-----NNIVDSFNKQILRIE 570
K D+ + +Q+ EQL++A+ E+E + L + N ++++ N+ +L E
Sbjct: 1236 AKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKE 1295
Query: 571 -EQHKLEINVLEEKQREEIK 589
E +L+ + ++ E+IK
Sbjct: 1296 SELTRLQAKISGHEKAEDIK 1315
Score = 42.3 bits (95), Expect = 0.005
Identities = 67/280 (23%), Positives = 129/280 (46%), Gaps = 32/280 (11%)
Query: 342 QKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-KSLEEQLNTELDNVNVMLSNKDKEIDV 400
++K + S K +L + +K NEK +SLE +NTE + + + K K+I
Sbjct: 588 EEKIVAYSSIAAKNAELEQELMEK-----NEKIRSLETNINTEHEKI-CLAFEKAKKIH- 640
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE 460
+ +K++ ++ LE LEK+ + ++ L + I + + L + +
Sbjct: 641 --------LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI--ICKQHHLESLD 690
Query: 461 RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCH 520
R L +SK E + ++ L QNQ SE K LD+ ++ ++ L L N+L+ +
Sbjct: 691 RLLTESK-GEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGN 749
Query: 521 YQKQLEDAVLAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEI 577
+K E + K +E Q++L ++ + ++N I+ +Q ++ +Q +
Sbjct: 750 KEK-FEKQLKKKSEEVYCLQKELKIKNHSLQETS--EQNVILQHTLQQQQQMLQQETIRN 806
Query: 578 NVLEEKQRE-EIKLYRL------QLAQAAEKLGLLESKVE 610
LE+ Q + E ++ +L Q +AEKL +E K E
Sbjct: 807 GELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 846
Score = 41.5 bits (93), Expect = 0.009
Identities = 77/393 (19%), Positives = 160/393 (40%), Gaps = 36/393 (9%)
Query: 233 SELWGDKAERTTGYNRGDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAMKVD 292
++L K TG R K+++ + +EE K E + ++ + M +D
Sbjct: 852 ADLKRQKVIELTGTARQVKIEMDQYKEELSKME--KEIMHLKRDGENKAMHLSQLDMILD 909
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRKALEK---MICEVENFRVVADDAQKKTSHFE 349
+ K + K A L E +AL+K + E++N ++
Sbjct: 910 QTK-TELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELR 968
Query: 350 SELYKT-LDLAHDY---QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENY 405
L K L L Y +D +L+ K +E++ EL ++ L ++ E LK+
Sbjct: 969 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDK-KQELLEMDQALKERNWE---LKQRA 1024
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND------------E 453
V L+ + + +E+ + K + + ++ + E NK+I+S+ND E
Sbjct: 1025 AQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 1084
Query: 454 TLLLTQERDL--LKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE 511
++L E+++ LK ++ + R +E + E++ + K+ L E++ R+ ++
Sbjct: 1085 FIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQ 1144
Query: 512 LQKNEL-KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR-- 568
EL + +Q+ + +L E D + E DA N++ + +R
Sbjct: 1145 NSHTELAEARHQQVQAQREIERLS--SELEDMKQLSKEKDAH--GNHLAEELGASKVREA 1200
Query: 569 -IEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
+E + + EI L + + Y +++ E
Sbjct: 1201 HLEARMQAEIKKLSAEVESLKEAYHMEMISHQE 1233
Score = 39.1 bits (87), Expect = 0.049
Identities = 67/283 (23%), Positives = 126/283 (44%), Gaps = 35/283 (12%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQL---------NTELDNVNVMLSNKDKEIDVLKENYDTV 408
L + KC QL +K LEE++ N EL+ L K+++I L+ N +T
Sbjct: 569 LESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQ---ELMEKNEKIRSLETNINTE 625
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE--TLLLTQERDLLKS 466
+ K + LE+ K + +L K+ Q ++ T+ + Q+ + K
Sbjct: 626 HEKICLAFEKAKKIH--LEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQ 683
Query: 467 KVNEERSRCAVIEQQLCEKQN-QCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHY 521
E R + +K+N + E LK +E V+ L LE+ K EL H
Sbjct: 684 HHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHL 743
Query: 522 QKQLEDAVLAKLQEFQEQLDRAERE---MENDARLKENNIVDSFNKQILRIEEQHKLEIN 578
QLE ++F++QL + E ++ + ++K +++ ++ + ++ QH L+
Sbjct: 744 -NQLE----GNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVIL---QHTLQ-Q 794
Query: 579 VLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAA 621
+ Q+E I+ L+ Q KL SK+E + +++ E++A
Sbjct: 795 QQQMLQQETIRNGELEDTQT--KLEKQVSKLEQELQKQRESSA 835
Score = 37.9 bits (84), Expect = 0.11
Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 2/181 (1%)
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
Q+ ++S EE + ++D + K E + Y+ L+K K + E LEK
Sbjct: 208 QSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAE-ELSKAFQQYKKKVAEKLEKV 266
Query: 430 KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQC 489
+ + + N+T K + + + L E ++LK K+ + + +++L +
Sbjct: 267 QAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKN 326
Query: 490 SEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL-AKLQEFQEQLDRAEREME 548
SEV+ + + L LE + L+ + E+ L ++ E+LD ++E+E
Sbjct: 327 SEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIE 386
Query: 549 N 549
+
Sbjct: 387 S 387
>AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein.
Length = 1742
Score = 52.4 bits (120), Expect = 5e-06
Identities = 75/333 (22%), Positives = 158/333 (47%), Gaps = 37/333 (11%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE 378
R+R A+E+ + +++ + QK+ + + KT +L + KQL ++ + E
Sbjct: 949 RYRDAVEEKLAKLQKHNSELE-TQKEQIQLKLQ-EKTEELKEKMDNLTKQLFDDVQKEER 1006
Query: 379 QLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKS 438
Q + + + +K+I LKE K L D L+ +E E D K+
Sbjct: 1007 QRMLLEKSFELKTQDYEKQIQSLKEEI-------KALKDEKMQLQHLVEGEHVTSDGLKA 1059
Query: 439 NITELNKRIQSVN----DETLLLTQERDL---LKSKVNEERSRCAVIEQQLCEKQN---- 487
+ L+K++++++ + LL Q+ D+ ++S+ E R + + I +QL E +
Sbjct: 1060 EVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDV 1119
Query: 488 QCSEVLKKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAER 545
+ ++ + L D E+ + L+ L+ H+Q Q +D +++ ++ +
Sbjct: 1120 RSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQ-KDCYEKEIEALNFKVVHLSQ 1178
Query: 546 EMENDARL--KENNIVDSFNKQILRIEEQH------KLEINVLEEKQREEIKLYRLQLAQ 597
E+ + +L +EN+I +S ++ R+ ++ K +I+ L EKQ+++++ ++L +
Sbjct: 1179 EINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISEL-EKQKQDLE---IRLNE 1234
Query: 598 AAEKL-GLLESKVECQRRRRGETAARLHAALQA 629
AEK+ G LE ++ Q R E AL+A
Sbjct: 1235 QAEKMKGKLE-ELSNQLHRSQEEEGTQRKALEA 1266
Score = 43.2 bits (97), Expect = 0.003
Identities = 58/232 (25%), Positives = 103/232 (44%), Gaps = 16/232 (6%)
Query: 376 LEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDS 435
L QL + + L +++KE L E ++ L + ++ LE LEK +
Sbjct: 883 LNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAA----T 938
Query: 436 TKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK 495
+ N E KR + +E L Q+ + S++ ++ + + Q+ E+ + + L K
Sbjct: 939 HRRNYEEKGKRYRDAVEEKLAKLQKHN---SELETQKEQIQLKLQEKTEELKEKMDNLTK 995
Query: 496 CDFLDNEVKTLRQHLELQKN-ELKCH-YQKQ---LEDAVLAKLQEFQEQLDRAEREMEND 550
D+ K RQ + L+K+ ELK Y+KQ L++ + A E + E E
Sbjct: 996 -QLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTS 1054
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKL 602
LK V +KQ+ I E K EI +L+ ++ + K + Q + EK+
Sbjct: 1055 DGLKAE--VARLSKQVKTISEFEK-EIELLQAQKIDVEKHVQSQKREMREKM 1103
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 52.4 bits (120), Expect = 5e-06
Identities = 75/308 (24%), Positives = 142/308 (46%), Gaps = 26/308 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKTLDLAHDY-QDKCKQLQN 371
A D ++LE+ I E+ +A ++ ++ + E+ L Y + + +L+
Sbjct: 43 AMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEA 102
Query: 372 EKKSLEEQL----NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE--- 424
+ + LEEQL + + + N +L + + +V E+ + + L +QLT+ +L+E
Sbjct: 103 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERES 162
Query: 425 ---ALEKEKFAHDST-KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
AL+ + A +S + TEL + +E LT RD ++ K + R+ C VI
Sbjct: 163 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI-T 221
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQ 539
L E+ NQ +E + L+N+ L + L+ Q + E D + ++ E + Q
Sbjct: 222 DLEEQLNQLTEDNAE---LNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 278
Query: 540 LDRAEREME---NDARLKENNIVD--SFNKQILRIEEQHKLEINVL-EEKQREEIKLYRL 593
L ++ ME + E ++D + N ++L E Q + +VL +EK + E ++ L
Sbjct: 279 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 338
Query: 594 QLAQAAEK 601
Q EK
Sbjct: 339 QRMLDTEK 346
Score = 49.2 bits (112), Expect = 5e-05
Identities = 81/343 (23%), Positives = 152/343 (44%), Gaps = 45/343 (13%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRK---ALEKM----------ICEVE-NFRVVA 338
+A++ IS+LR+ L + E ++RK LEK+ + E+E R V+
Sbjct: 77 KAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVS 136
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
+ +++ + +L + + + + LQ + +LE QL + + ++EI
Sbjct: 137 LEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEI 196
Query: 399 DVLKENYDTVMRLNKQL-TDC--VKNLEEALEKEKFAHDSTKSNITELNKRI---QSVND 452
L + D + R L C + +LEE L + + + L+K++ ND
Sbjct: 197 QALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND 256
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQ-HL 510
E + L E D L+ ++ E E QL Q Q E LK C L+ +V L +
Sbjct: 257 EIVQLRSEVDHLRREITER-------EMQL-TSQKQTMEALKTTCTMLEEQVMDLEALND 308
Query: 511 ELQKNELKCHYQKQL----EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
EL + E + + + + +++E Q LD E ++ AR + I +S +Q+
Sbjct: 309 ELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLD---TEKQSRAR-ADQRITES--RQV 362
Query: 567 LRIE-EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+ + ++HK EI L++ +E+ +L+ ++KL LE K
Sbjct: 363 VELAVKEHKAEILALQQALKEQ----KLKAESLSDKLNDLEKK 401
Score = 44.0 bits (99), Expect = 0.002
Identities = 77/332 (23%), Positives = 139/332 (41%), Gaps = 39/332 (11%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKA-LEKMICEVENFRVVADDAQKKTSHFESELYKTLD 357
I+ L E +LT D AE ++ L K + E + + H E+ +
Sbjct: 220 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 277
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+ + L+ LEEQ+ +L+ +N L K+++ E + +V+ K +
Sbjct: 278 QLTSQKQTMEALKTTCTMLEEQV-MDLEALNDELLEKERQW----EAWRSVLGDEKSQFE 332
Query: 418 C-VKNLEEALEKEKFAHDSTKSNITELNKRIQ-SVND---ETLLLTQ-------ERDLLK 465
C V+ L+ L+ EK + ITE + ++ +V + E L L Q + + L
Sbjct: 333 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 392
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+N+ + A++E Q + + L E L+Q ++LQKN
Sbjct: 393 DKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNH--------- 443
Query: 526 EDAVLAKLQEFQEQLDRAE--REMENDARLKENNIVDSFNKQILRIE----EQHKLEINV 579
+ Q QE LDRA+ + +D + NI ++ + +++E +Q KL I+
Sbjct: 444 ---IFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKL-IDF 499
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
L+ K + K ++ L KL L + K C
Sbjct: 500 LQAKMDQPAKKKKVPLQYNELKLALEKEKARC 531
>AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein.
Length = 690
Score = 52.4 bits (120), Expect = 5e-06
Identities = 63/294 (21%), Positives = 131/294 (44%), Gaps = 22/294 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQ----NEKKSLEEQLNTELDNVNVMLSNKD 395
+A+++ H EL + +LA + KC +LQ E+K+ Q+ + V+ +
Sbjct: 356 EAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQ 415
Query: 396 K-EIDV--LKENYDTVMRLNK----QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ ID L+E D+ + + D + L +A K D+ +++ E K+++
Sbjct: 416 RLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVR 475
Query: 449 SVNDETLLLTQERDL-LKSKVNEERSRCAVIEQQLCEK----QNQCSEVLKKCDFLDNEV 503
+ + E + + S N + RC E Q E+ Q + ++ K+ + L+ E
Sbjct: 476 AELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETEC 535
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ--LDRAEREMEND-ARLKENNIVD 560
+L++ L +EL+ +K+L ++ L+ + L + +E+EN LKE ++ D
Sbjct: 536 HSLKRENVLLSSELQ-RQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD 594
Query: 561 SFN-KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQA-AEKLGLLESKVECQ 612
S + K +L E ++ EK + + +L+ EK + + +C+
Sbjct: 595 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCK 648
Score = 41.5 bits (93), Expect = 0.009
Identities = 58/264 (21%), Positives = 113/264 (42%), Gaps = 26/264 (9%)
Query: 367 KQLQNEKKSLEEQLNT-ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA 425
K ++ K S E Q E D + + +K+K D + LN+ L V L++
Sbjct: 289 KAVEETKLSKENQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEPLAK-VSLLKDD 347
Query: 426 LEKEKFAHDSTKSNITELNKRI-----------QSVNDETLLLTQERDLLKSKVNEERSR 474
L+ + + K I L K + Q + LL +ER +++V E +
Sbjct: 348 LQGAQ-SEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQ 406
Query: 475 CAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL--AK 532
V++ QL ++ + +E L+ + D+E+ + R L ++E+ +Q + A
Sbjct: 407 IQVLQAQL-QRLHIDTENLR--EEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTD 463
Query: 533 LQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
+ QE+L + E+E + + K+I ++ +L E++QREE +
Sbjct: 464 IASLQEELKKVRAELE-----RWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQ 518
Query: 593 LQLAQAAEKLGLLESKVECQRRRR 616
+L + ++ LE+ EC +R
Sbjct: 519 GELEKLRKEWNALET--ECHSLKR 540
Score = 34.3 bits (75), Expect = 1.4
Identities = 70/326 (21%), Positives = 136/326 (41%), Gaps = 36/326 (11%)
Query: 330 EVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNT--ELDNV 387
EV ++ A + EL + H+Y+ K ++ ++ L+E++ +L V
Sbjct: 97 EVMGNQLQACSKNQTEDSLRKELIALQEDKHNYETTAK--ESLRRVLQEKIEVVRKLSEV 154
Query: 388 NVMLSNKDKEIDVLKE-NYDTVMRL----NK------QLTDCVKNLEEALEKEKFAHDST 436
LSN + E LKE N T L NK ++ D L+ A K++
Sbjct: 155 ERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQKG 214
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ-NQCSEVLKK 495
++ EL +I + ++ L + + L++ + R +++ L K C+ + +
Sbjct: 215 QAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQ- 273
Query: 496 CDFLDNEVKTLRQ-HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEN---DA 551
F++ + K + + HL E K + Q AK +F + L ++ + + DA
Sbjct: 274 --FIECQKKLIVEGHLTKAVEETKLSKENQTR----AKESDFSDTLSPSKEKSSDDTTDA 327
Query: 552 RLKENNIVDSFNK--------QILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLG 603
++ E ++ + K Q + E + K EI L ++ E +L R + E
Sbjct: 328 QMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQA 387
Query: 604 LLESKVECQRRRRGETAARLHAALQA 629
LLE + + R + E+ ++ LQA
Sbjct: 388 LLEEERKAYRNQVEESTKQIQ-VLQA 412
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 52.4 bits (120), Expect = 5e-06
Identities = 75/308 (24%), Positives = 142/308 (46%), Gaps = 26/308 (8%)
Query: 316 AEDRHRKALEKMICEVENFRVVADDAQ---KKTSHFESELYKTLDLAHDY-QDKCKQLQN 371
A D ++LE+ I E+ +A ++ ++ + E+ L Y + + +L+
Sbjct: 317 AMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEA 376
Query: 372 EKKSLEEQL----NTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE--- 424
+ + LEEQL + + + N +L + + +V E+ + + L +QLT+ +L+E
Sbjct: 377 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERES 436
Query: 425 ---ALEKEKFAHDST-KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ 480
AL+ + A +S + TEL + +E LT RD ++ K + R+ C VI
Sbjct: 437 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVI-T 495
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE-DAVLAKLQEFQEQ 539
L E+ NQ +E + L+N+ L + L+ Q + E D + ++ E + Q
Sbjct: 496 DLEEQLNQLTEDNAE---LNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 552
Query: 540 LDRAEREME---NDARLKENNIVD--SFNKQILRIEEQHKLEINVL-EEKQREEIKLYRL 593
L ++ ME + E ++D + N ++L E Q + +VL +EK + E ++ L
Sbjct: 553 LTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVREL 612
Query: 594 QLAQAAEK 601
Q EK
Sbjct: 613 QRMLDTEK 620
Score = 49.6 bits (113), Expect = 3e-05
Identities = 65/328 (19%), Positives = 142/328 (43%), Gaps = 21/328 (6%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
M+V + D A+ L + + + E ++ +E+M + A++++ +
Sbjct: 74 MEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLY 133
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTEL-DNVNVMLSNKDKEIDV--LKENY 405
ESEL ++ A +++ K + Q++ ++Q E+ + + N ++++ + L+E
Sbjct: 134 ESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKL 193
Query: 406 DTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
+ ++ + + T+ ++N+ +A E+ + + +L R S L E + L+
Sbjct: 194 EKAVKASTEATELLQNIRQAKER-------AERELEKLQNREDSSEGIRKKLV-EAEELE 245
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K E + +E L +K+ E +K LDN++K E +N ++ H ++
Sbjct: 246 EKHREAQVSAQHLEVHLKQKEQHYEEKIK---VLDNQIKKDLADKETLENMMQRHEEEAH 302
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINV-LEEKQ 584
E K+ Q+ + A M++ R E IV+ L + N+ +E+
Sbjct: 303 EK---GKILSEQKAMINA---MDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEM 356
Query: 585 REEIKLYRLQLAQAAEKLGLLESKVECQ 612
E++ + L A KL K+E Q
Sbjct: 357 ISELRQQKFYLETQAGKLEAQNRKLEEQ 384
Score = 49.2 bits (112), Expect = 5e-05
Identities = 81/343 (23%), Positives = 152/343 (44%), Gaps = 45/343 (13%)
Query: 293 RAKDAAISKLREAWLRLTNSLDRAEDRHRK---ALEKM----------ICEVE-NFRVVA 338
+A++ IS+LR+ L + E ++RK LEK+ + E+E R V+
Sbjct: 351 KAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVS 410
Query: 339 DDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEI 398
+ +++ + +L + + + + LQ + +LE QL + + ++EI
Sbjct: 411 LEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEI 470
Query: 399 DVLKENYDTVMRLNKQL-TDC--VKNLEEALEKEKFAHDSTKSNITELNKRI---QSVND 452
L + D + R L C + +LEE L + + + L+K++ ND
Sbjct: 471 QALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND 530
Query: 453 ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK-KCDFLDNEVKTLRQ-HL 510
E + L E D L+ ++ E E QL Q Q E LK C L+ +V L +
Sbjct: 531 EIVQLRSEVDHLRREITER-------EMQL-TSQKQTMEALKTTCTMLEEQVMDLEALND 582
Query: 511 ELQKNELKCHYQKQL----EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQI 566
EL + E + + + + +++E Q LD E ++ AR + I +S +Q+
Sbjct: 583 ELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLD---TEKQSRAR-ADQRITES--RQV 636
Query: 567 LRIE-EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
+ + ++HK EI L++ +E+ +L+ ++KL LE K
Sbjct: 637 VELAVKEHKAEILALQQALKEQ----KLKAESLSDKLNDLEKK 675
Score = 44.0 bits (99), Expect = 0.002
Identities = 77/332 (23%), Positives = 139/332 (41%), Gaps = 39/332 (11%)
Query: 299 ISKLREAWLRLTNSLDRAEDRHRKA-LEKMICEVENFRVVADDAQKKTSHFESELYKTLD 357
I+ L E +LT D AE ++ L K + E + + H E+ +
Sbjct: 494 ITDLEEQLNQLTE--DNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREM 551
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
+ + L+ LEEQ+ +L+ +N L K+++ E + +V+ K +
Sbjct: 552 QLTSQKQTMEALKTTCTMLEEQV-MDLEALNDELLEKERQW----EAWRSVLGDEKSQFE 606
Query: 418 C-VKNLEEALEKEKFAHDSTKSNITELNKRIQ-SVND---ETLLLTQ-------ERDLLK 465
C V+ L+ L+ EK + ITE + ++ +V + E L L Q + + L
Sbjct: 607 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 666
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
K+N+ + A++E Q + + L E L+Q ++LQKN
Sbjct: 667 DKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNH--------- 717
Query: 526 EDAVLAKLQEFQEQLDRAE--REMENDARLKENNIVDSFNKQILRIE----EQHKLEINV 579
+ Q QE LDRA+ + +D + NI ++ + +++E +Q KL I+
Sbjct: 718 ---IFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKL-IDF 773
Query: 580 LEEKQREEIKLYRLQLAQAAEKLGLLESKVEC 611
L+ K + K ++ L KL L + K C
Sbjct: 774 LQAKMDQPAKKKKVPLQYNELKLALEKEKARC 805
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/258 (24%), Positives = 116/258 (44%), Gaps = 12/258 (4%)
Query: 371 NEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEK 430
NE++ L L + KD+E+ L+ ++ ++L VK L+E L K++
Sbjct: 1039 NEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKE 1098
Query: 431 FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
H S +E R + + L E L+ + +++ + +E+ L ++ +
Sbjct: 1099 KEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA 1158
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL-DRAEREMEN 549
E D+ ++TL+ LE + EL H Q L A +L F+ ++ D ++ E E
Sbjct: 1159 E-------RDSALETLQGQLEEKAQELG-HSQSALASA-QRELAAFRTKVQDHSKAEDEW 1209
Query: 550 DARL-KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
A++ + + N I +EE+ + + EK+ E +L RL +A+ +EK LE
Sbjct: 1210 KAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAE-SEKSQKLEES 1268
Query: 609 VECQRRRRGETAARLHAA 626
C R+R+ T L A
Sbjct: 1269 CACCRQRQPATVPELQNA 1286
Score = 47.6 bits (108), Expect = 1e-04
Identities = 86/376 (22%), Positives = 162/376 (43%), Gaps = 45/376 (11%)
Query: 289 MKVDRAK-DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEV-ENFRVVADDAQKKTS 346
+K ++++ D I++L E L+ L R H + L+ + E+ E + +K +
Sbjct: 302 LKTEKSQMDRKINQLSEENGDLSFKL-REFASHLQQLQDALNELTEEHSKATQEWLEKQA 360
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNV---NVMLSNKDKEIDVLKE 403
E EL L ++K + LQ + LEE L+ DN + +++ LK+
Sbjct: 361 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ 420
Query: 404 NYDTVMRLNKQLTDCVKNLE------EAL----------EKEKFAH-----DSTKSNITE 442
T+ N QL V+ LE EA EK++ + S+ SN+++
Sbjct: 421 EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ 480
Query: 443 LNKRIQSVND--------ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLK 494
+ ++ + + LT E L + + ++ A ++QQ EKQ Q ++ L+
Sbjct: 481 AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ 540
Query: 495 KCDFLDNEVKTLRQHLELQKNELKCHYQ--KQLEDAVLAKLQEFQEQLDRA--EREM--- 547
+ + + LR +E + LK Q K++ + A Q+ +QL A ERE
Sbjct: 541 Q---QEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLR 597
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
E DA LK+ ++ L I +Q N + + + + + A+ + K+ L++
Sbjct: 598 ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQA 657
Query: 608 KVECQRRRRGETAARL 623
VE R+ + E A++
Sbjct: 658 CVETARQEQHEAQAQV 673
Score = 46.0 bits (104), Expect = 4e-04
Identities = 65/304 (21%), Positives = 121/304 (39%), Gaps = 35/304 (11%)
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEE--------------QLNTELDNVNVMLS 392
HFE E + L D Q L K+ LE+ L +EL +N +
Sbjct: 456 HFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQ 515
Query: 393 NKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVND 452
+D+E+ LK+ QL ++ E+A + + + S++ + ++++ V +
Sbjct: 516 QQDQELAGLKQQ---AKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAE 572
Query: 453 ETLLLTQERDLLKSKVNEE-----RSRCAVIEQ-QLCEKQNQCS-EVLKKCDFLDNEVKT 505
+ Q+ + EE R R A ++Q + EK+ E+L++ + NE +
Sbjct: 573 KQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARD 632
Query: 506 LRQHLELQKNELKCHYQKQLED----AVLAKLQEFQEQLDRAEREME---NDARLKENNI 558
Q Q K +++E+ A+ ++ + Q AE E++ + E
Sbjct: 633 SAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKER 692
Query: 559 V----DSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
V D +Q+ ++E K+ LEE++R Q +E S VE +R
Sbjct: 693 VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKR 752
Query: 615 RRGE 618
R E
Sbjct: 753 ERKE 756
Score = 44.8 bits (101), Expect = 0.001
Identities = 56/275 (20%), Positives = 124/275 (45%), Gaps = 21/275 (7%)
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAH 433
++LE++ +L+ + L ++ D + + R +L+ V+ L+ +E +
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666
Query: 434 DSTKSNITELNKRIQSVND---ETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCS 490
++ + EL +++S E + QE+D L+ ++ + V + L E++ + +
Sbjct: 667 HEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA 726
Query: 491 EVLK---KC-DFLDNEVKTLRQHLELQKNELKCHY--QKQLEDAVLAKLQEFQEQLDRAE 544
+ L+ +C L E ++L + + ++ EL+ +K LE +L + Q + +
Sbjct: 727 DALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLLQLGEAHQAETEVLR 786
Query: 545 REMEND--ARLKENNIVDSFNKQIL------RIEEQHKLEINVLEEKQ----REEIKLYR 592
RE+ A+ + + K++ +Q + + + ++Q +EE + R
Sbjct: 787 RELAEAMAAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKAR 846
Query: 593 LQLAQAAEKLGLLESKVECQRRRRGETAARLHAAL 627
+L +A EK+ +ES E Q R+ A LHA L
Sbjct: 847 QELQEAKEKVAGIESHSELQISRQQNKLAELHANL 881
Score = 44.4 bits (100), Expect = 0.001
Identities = 64/282 (22%), Positives = 125/282 (44%), Gaps = 28/282 (9%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN-KQLTDCV--KNLE 423
KQL +E+ + +E L EL +L+ KD +I ++++ D + LN KQ + K LE
Sbjct: 221 KQLADERSNRDE-LELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELE 279
Query: 424 EALEKEKF----AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
E +K + H++ K +L ++ + L++E L K+ E S ++
Sbjct: 280 ELRDKNESLTMRLHETLK-QCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQ 338
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
L E + S+ + ++L+ + + L + L + KC +K + + KL + +E
Sbjct: 339 DALNELTEEHSKATQ--EWLEKQAQ-LEKELSAALQDKKCLEEK--NEILQGKLSQLEEH 393
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIE--------EQHKLEINVLE-EKQREEIKL 590
L + + +N + K + D + L+ E Q + + +LE E+ ++E KL
Sbjct: 394 LSQLQ---DNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKL 450
Query: 591 Y--RLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAH 630
R + ++L L + ++ + L A QAH
Sbjct: 451 LAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAH 492
Score = 33.1 bits (72), Expect = 3.2
Identities = 43/178 (24%), Positives = 84/178 (47%), Gaps = 22/178 (12%)
Query: 319 RHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTL---DLAHDYQD-KCKQLQ---N 371
++ A K++ E + F+ ++ QK T+ E EL K L D A Q K K +Q
Sbjct: 1511 KYEGAKVKVLEERQRFQ---EERQKLTAQVE-ELSKKLADSDQASKVQQQKLKAVQAQGG 1566
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDK-------EIDVLKENYDTVMRLNKQLTDCVKNLEE 424
E + ++ +L+ + LS K++ +++ K +YD + N++L + +++LE+
Sbjct: 1567 ESQQEAQRFQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ 1626
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
L+KE + ++ L +Q +T Q L ++V ++ A +QQL
Sbjct: 1627 -LQKE---NKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQL 1680
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 52.0 bits (119), Expect = 6e-06
Identities = 62/302 (20%), Positives = 137/302 (45%), Gaps = 22/302 (7%)
Query: 322 KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLN 381
K + M E + + ++ + E ++ L +D Q + + Q+ EE+ +
Sbjct: 847 KEMASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906
Query: 382 TELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNIT 441
+ N + L K KE++ E + +N +LT +N+E+ + K D + +
Sbjct: 907 QLIKN-KIQLEAKVKEMN---ERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELTLA 962
Query: 442 ELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDN 501
++ K + ++ LT+E + ++E ++ ++ L E Q + L+ + N
Sbjct: 963 KVEKEKHATENKVKNLTEEM----AGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1018
Query: 502 EVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDS 561
+ + LE Q ++L+ +++ ++ + L+RA+R++E D +L + +I+D
Sbjct: 1019 TLTKAKVKLEQQVDDLEGSLEQE---------KKVRMDLERAKRKLEGDLKLTQESIMDL 1069
Query: 562 FN-KQILRIEEQHK-LEINVLEEKQREEIKL---YRLQLAQAAEKLGLLESKVECQRRRR 616
N KQ L + K E+N L + +E L + +L + ++ LE ++E +R R
Sbjct: 1070 ENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTAR 1129
Query: 617 GE 618
+
Sbjct: 1130 AK 1131
Score = 50.8 bits (116), Expect = 1e-05
Identities = 67/299 (22%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK+ +EL+K + + + + +
Sbjct: 1441 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKR 1500
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L+E E+ ++ L + K I L+ ++ KQL L+ ALE+ +
Sbjct: 1501 ENKNLQE----EISDLTEQLGSSGKTIHELE-------KVRKQLEAEKMELQSALEEAEA 1549
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA-VIEQQLCEKQNQCS 490
+ + + I + E E+D + R ++ L + +
Sbjct: 1550 SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRN 1609
Query: 491 EVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMEND 550
E L+ ++ ++ + L N + QKQ++ ++ + L++ Q QLD A R ND
Sbjct: 1610 EALRVKKKMEGDLNEMEIQLS-HANRMAAEAQKQVK-SLQSLLKDTQIQLDDAVR--AND 1665
Query: 551 ARLKEN-NIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESK 608
LKEN IV+ N +EE V+E+ +R KL +L + +E++ LL S+
Sbjct: 1666 -DLKENIAIVERRNNLQAELEELRA----VVEQTERSR-KLADRELIETSERVQLLHSQ 1718
Score = 44.4 bits (100), Expect = 0.001
Identities = 52/306 (16%), Positives = 123/306 (40%), Gaps = 5/306 (1%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A + KLR L+ L+ +R +A C++E + + QK
Sbjct: 1122 LEAERTARAKVEKLRSD---LSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDL 1178
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S E+D + N + +
Sbjct: 1179 EEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1238
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
++ L + LE+ + + + + T+ ++ +L + + E L+++ D ++ +
Sbjct: 1239 IKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI 1298
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA 528
++ QQL + + Q E +K + L + +++ R +L + + + + + E
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE-- 1356
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEI 588
+ L + ++ + + E DA + + ++ K R++E + V + E
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 589 KLYRLQ 594
+RLQ
Sbjct: 1417 TKHRLQ 1422
Score = 43.2 bits (97), Expect = 0.003
Identities = 68/356 (19%), Positives = 151/356 (42%), Gaps = 35/356 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++AL+ + E + + +++ E L + +
Sbjct: 985 LDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E L + ++ L KD E++ L + L QL
Sbjct: 1045 RMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 416 TDCVKNL-------EEALEKEKFAH---DSTKSNIT----ELNKRIQSVNDET---LLLT 458
+K L EE LE E+ A + +S+++ E+++R++ T + +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMN 1164
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1223
Query: 517 LKCHYQ---KQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIE 570
K +E + AK E++ R + N+ R K V+ Q +++
Sbjct: 1224 FKLELDDVTSNMEQIIKAKAN--LEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQ 1281
Query: 571 EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
++ L+EK+ +L R +L ++L L+ ++E + + + A L +A
Sbjct: 1282 TENGELSRQLDEKEALISQLTRGKLTY-TQQLEDLKRQLEEEVKAKNALAHALQSA 1336
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 52.0 bits (119), Expect = 6e-06
Identities = 61/300 (20%), Positives = 133/300 (44%), Gaps = 36/300 (12%)
Query: 322 KALEKMICEVENFRVVADDAQKKT----SHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
K ++ ++EN + D+ KK S +S++ L Q K K+LQ + LE
Sbjct: 1 KLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 60
Query: 378 EQLNTELDN---VNVMLSNKDKEIDVLKENYD-------TVMRLNKQLTDCVKNLEEALE 427
E++ E + + S+ +E++ + E + T + +NK+ + + LE
Sbjct: 61 EEIEAERTSRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDLE 120
Query: 428 KEKFAHDSTKS--------NITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
+ H++T + ++ EL ++I ++ L +E+ +K ++++ S +
Sbjct: 121 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 180
Query: 480 ------QQLCEK-QNQCSEVLKKCDFLDNEVKTL-RQHLELQKNELKCHYQKQLEDAVLA 531
+++C ++Q SE+ K + + L Q LQ+N+++ Q +D +
Sbjct: 181 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLET 240
Query: 532 KL----QEFQEQLDRAEREMENDARLKE--NNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
+L Q F +Q++ +R++E + + K + + S + EQ++ E E QR
Sbjct: 241 QLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQR 300
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/302 (20%), Positives = 129/302 (42%), Gaps = 28/302 (9%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E V + QK++ +EL+K + + D+ + L+
Sbjct: 382 ALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETLKR 441
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
E K+L++ E+ ++ ++ K I L+ ++ KQ+ L+ ALE+ +
Sbjct: 442 ENKNLQQ----EISDLTEQIAEGGKRIHELE-------KIKKQVEQEKSELQAALEEAEA 490
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERD-----LLKSKVNEERSRCAVIEQQLCEKQ 486
+ + + I + + V E E+D + ++ + E S + + ++ +
Sbjct: 491 SLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEI-RSR 549
Query: 487 NQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
N + KK + NE++ H E +YQ A L++ Q LD A R
Sbjct: 550 NDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQN-----TQAILKDTQLHLDDALRS 604
Query: 547 MENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLE 606
E+ LKE + +L+ E + E+ E+ K+ +L A+E++ LL
Sbjct: 605 QED---LKEQLAMVERRANLLQAEIE---ELRATLEQTERSRKIAEQELLDASERVQLLH 658
Query: 607 SK 608
++
Sbjct: 659 TQ 660
Score = 41.1 bits (92), Expect = 0.012
Identities = 55/295 (18%), Positives = 117/295 (39%), Gaps = 13/295 (4%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF 348
++ +R A KLR L+ L+ +R +A+ ++E + + QK
Sbjct: 63 IEAERTSRAKAEKLRSD---LSRELEEISERLEEAVGATSTQIEMNKKREAEFQKMRRDL 119
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E + A + K E + L + S EID L N +TV
Sbjct: 120 EEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETV 179
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTK---SNITELNKRIQSVNDETLLLTQERDLLK 465
+ L + LE+ L + K + + +++T R+Q E E+D L+
Sbjct: 180 SKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLE 239
Query: 466 SKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
++++ + QQ+ E + Q E +K L + +++ R +L + + + + +
Sbjct: 240 TQLSRGKQ---AFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKA 296
Query: 526 EDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIE--EQHKLEIN 578
E + + + ++ + + E DA + + ++ K R++ E+H +N
Sbjct: 297 E--LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN 349
Score = 39.9 bits (89), Expect = 0.028
Identities = 77/374 (20%), Positives = 146/374 (39%), Gaps = 41/374 (10%)
Query: 249 GDKVDIIKLEEERLKREHCEAMIXXXXXXXXXXXXXXAVAM--KVDRAKDAAISKLR--- 303
G+++D ++ +++L++E E + A K+ RA + +S+++
Sbjct: 145 GEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKE 204
Query: 304 EAWLRLTNSLDRAEDR--------HRKALEKMICEVENFR---VVADDAQKKTSHFESEL 352
E RL N L R R+ EK E + R ++ E E+
Sbjct: 205 EEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEEEI 264
Query: 353 YKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
LAH Q ++ EE+ + + M S + E+ + Y+T
Sbjct: 265 KAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM-SKANSEVAQWRTKYET----- 318
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
+ LEEA +K + ++ +N + S+ L E + L V
Sbjct: 319 -DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTN 377
Query: 473 SRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQKQLEDAV 529
+ CA ++++ +E +KC+ +++ ++ L + ++K Y++ L+
Sbjct: 378 AACAALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLE 437
Query: 530 LAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN-VLEEK-- 583
K + QE D E+ E R+ E ++ KQ+ EQ K E+ LEE
Sbjct: 438 TLKRENKNLQQEISDLTEQIAEGGKRIHE---LEKIKKQV----EQEKSELQAALEEAEA 490
Query: 584 --QREEIKLYRLQL 595
+ EE K+ R+QL
Sbjct: 491 SLEHEEGKILRIQL 504
Score = 39.1 bits (87), Expect = 0.049
Identities = 56/296 (18%), Positives = 126/296 (42%), Gaps = 33/296 (11%)
Query: 321 RKALEKMICEVENFRVVAD-DAQKKTSHFESELYKTLDLAHDYQD-------KCKQLQNE 372
++A+ K EV +R + DA ++T E K D ++ KC L+
Sbjct: 299 QRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKT 358
Query: 373 KKSLE---EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKE 429
K+ L+ E L +++ N + DK+ + N+D ++ KQ + + E+ +KE
Sbjct: 359 KQRLQNEVEDLMIDVERTNAACAALDKK----QTNFDKILAEWKQKCEETHAVLESFQKE 414
Query: 430 -----------KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVI 478
K A++ + + L + +++ E LT++ +++E +
Sbjct: 415 SRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV 474
Query: 479 EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQE 538
EQ+ E Q E + E K LR ++L+ N++K +++ + ++ + +
Sbjct: 475 EQEKSELQAALEEA--EASLEHEEGKILR--IQLEVNQVKSEVDRKIAEKD-EEIDQMKR 529
Query: 539 QLDRAEREMEN--DARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
R E M++ +A ++ N K++ + ++++N E+++ Y+
Sbjct: 530 NHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQ 585
>U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein.
Length = 3321
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 15/251 (5%)
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE---RDLLKSKVNE 470
QL V+ L +E+EK + ++E ++ SV + LL ++ RDL KS + E
Sbjct: 2548 QLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSV--QKLLAAEQTVVRDL-KSDLCE 2604
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
R + + + LCE Q + ++ +NE+K Q LE ++ + + Q QLE+ L
Sbjct: 2605 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRA-LQSQLEEEQL 2663
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
LQ + Q +A E+ A L+ S + + ++ + + N+ +E + E +
Sbjct: 2664 RHLQR-ESQSAKALEELR--ASLETQRAQSS--RLCVALKHEQTAKDNLQKELRIEHSRC 2718
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGETAARL-HAALQAHWRHALRILAAPHHDLGTHS 649
L LAQ +L L+ + ++ R E + L H L A H D H
Sbjct: 2719 EAL-LAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH- 2776
Query: 650 HSTPSNVSEHK 660
H+ + E K
Sbjct: 2777 HALLQKLKEEK 2787
Score = 44.4 bits (100), Expect = 0.001
Identities = 67/283 (23%), Positives = 116/283 (40%), Gaps = 23/283 (8%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
K Q K +L+++L E +L+ + ++ L++ D ++ L L EAL
Sbjct: 2698 KHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQK--DLAAEKSRTL-----ELSEAL 2750
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
E+ + E + LL + + KS+V + ++ ++QQ Q
Sbjct: 2751 RHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEE--KSRVVDLQAMLEKVQQQALHSQ 2808
Query: 487 NQC-SEVLKKCDFLDNE------VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
Q +E K C+ L E +K+ + L QK EL+C +++ E + + Q
Sbjct: 2809 QQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSH 2868
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRLQLAQA 598
E+E AR + R ++ K ++ LE ++QR+ K+ +LQ
Sbjct: 2869 PRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQ---- 2924
Query: 599 AEKLGLLESKVECQRRRRGETAARLHAALQA-HWRHALRILAA 640
+ + LESK E R +AR A A H R R L A
Sbjct: 2925 -QTVRDLESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEA 2966
Score = 40.7 bits (91), Expect = 0.016
Identities = 67/326 (20%), Positives = 144/326 (44%), Gaps = 28/326 (8%)
Query: 297 AAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRV-VADDAQKKTSHFESELYKT 355
A + K+ + + +L E H+ A+EK+ ++++ +D + K E E
Sbjct: 389 AELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLE 448
Query: 356 LD-LAHDYQDKCKQLQNEKKSLEEQLNT------ELDNVNVMLSNKDKEIDVLKENYDTV 408
L+ L Y+D Q Q E + L QL++ EL ++ L + ++ L++
Sbjct: 449 LENLQASYEDLKAQSQEEIRRLWSQLDSARTSRQELSELHEQLLARTSRVEDLEQ---LK 505
Query: 409 MRLNKQLTDCVKNLEEALEKE-KFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
R Q ++ L EK+ + A + + ++T L +R+Q ++ LL + E L
Sbjct: 506 QREKTQHESELEQLRIYFEKKLRDAEKTYQEDLTLLQQRLQGAREDALLDSVEVGLSCVG 565
Query: 468 VNE--ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL 525
+ E E+ R +++ E+ E L + F ++ R LE ++ L ++ +
Sbjct: 566 LEEKPEKGRKDHVDELEPERHK---ESLPR--FQAELEESHRHQLEALESPLCIQHEGHV 620
Query: 526 EDAVLAKLQEFQEQ--LDRAEREMENDARLKENNIVDSFNK-------QILRIEEQHKLE 576
D + + L+ +E + + + D + ++L +E +HK++
Sbjct: 621 SDRCCVETSALGHEWRLEPSEGHSQELPWVHLQGVQDGDLEADTERAARVLGLETEHKVQ 680
Query: 577 INVLEEKQREEIKLYRLQLAQAAEKL 602
+++L+ + +EEI+L +++ EKL
Sbjct: 681 LSLLQTELKEEIELLKIENRNLFEKL 706
Score = 40.7 bits (91), Expect = 0.016
Identities = 74/347 (21%), Positives = 154/347 (44%), Gaps = 27/347 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ--L 369
SLD+ R+ +++ E E+ R ++ Q++ E +L + +Q L
Sbjct: 1458 SLDKHLRNQRQFMDEQAAEREHER---EEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPL 1514
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNK---DKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
E + L+ +L +LD N + K D+++ + +E + +N + V L+E +
Sbjct: 1515 DGEVELLQHKLREKLDEFNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEV 1574
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
EK+K + + L K Q ++ L T + L + E S ++ +
Sbjct: 1575 EKQKNIVKGLEQDKEVLKK--QQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEV 1632
Query: 487 NQCSEVLKKCDFLD--NEVKTLRQHLELQKNELKCHYQKQLE---DAVLAKLQEFQEQLD 541
Q + + ++ + LD +++ ++ LE KNE H +L+ L+E +E+
Sbjct: 1633 TQRALLRRESEVLDLKEQLEKMKGDLE-SKNEEILHLNLKLDMQNSQTAVSLRELEEENT 1691
Query: 542 RAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLEINVLE---EKQREEIKLYRLQLAQ 597
+ + ++E +++ + R++++ EI L EK + E+ L + +
Sbjct: 1692 SLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHE 1751
Query: 598 AAE-KLGLLESKVECQRR--RRGET-AARLHAALQAHWRHAL-RILA 639
++ + G L+S++ C + RG+ L AAL+A + AL R+LA
Sbjct: 1752 VSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEA--KEALSRLLA 1796
Score = 40.3 bits (90), Expect = 0.021
Identities = 64/279 (22%), Positives = 123/279 (44%), Gaps = 34/279 (12%)
Query: 351 ELYKTLDLAHDYQDKCKQLQNE---KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
EL+KT ++ + L+ K+ E +L EL+++ L +E L+E
Sbjct: 1318 ELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTR 1377
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
+ + + E AL KE D TK + R Q+ D + LL+Q + +L+S+
Sbjct: 1378 LWSRGEATATDAEAREAALRKE--VEDLTKE---QSETRKQAEKDRSALLSQMK-ILESE 1431
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVL-KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E+ S + + C KQ + L ++ LD ++ RQ ++ Q E + H +++ +
Sbjct: 1432 LEEQLS-----QHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAERE-HEREEFQ 1485
Query: 527 DAV---------LAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIEEQHK 574
+ AK Q + + D + ++ + L ++ + +D FN+ ++ E +
Sbjct: 1486 QEIQRLEGQLRQAAKPQPWGPR-DSQQAPLDGEVELLQHKLREKLDEFNELAIQKESADR 1544
Query: 575 LEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR 613
VL Q EEIK +K+ L+ +VE Q+
Sbjct: 1545 ---QVL--MQEEEIKRLEEMNINIRKKVAQLQEEVEKQK 1578
Score = 34.3 bits (75), Expect = 1.4
Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 440 ITELNKRIQSVNDETLLLTQER-----DLLKSKVNEERSRCAV-IEQQLCE-KQNQCSEV 492
+TEL + + S + L L Q R +LL+ + E+ + Q+ E K+ SE+
Sbjct: 277 LTELREMLNSRRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEM 336
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR--AEREMEND 550
K VKTL++ E +K+ + +K+L +++++ Q Q + AE+ E +
Sbjct: 337 EKNAQI----VKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELE 392
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
++ N + + + +E H+ I L E + E
Sbjct: 393 KIFQDKNQAE---RALRNLESHHQAAIEKLREDLQSE 426
Score = 33.1 bits (72), Expect = 3.2
Identities = 51/236 (21%), Positives = 109/236 (46%), Gaps = 22/236 (9%)
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L+ + S +KE E V+R +++L +C+ EE+ K + A + K+ T
Sbjct: 1269 QLEEARQLHSRFEKEFSFKNEETAQVVRKHQELLECL--TEESAAKAELALELHKTQGTL 1326
Query: 443 LNKRIQSVNDETLLLTQE--RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK--CDF 498
++++ + + +L +E L ++ R + Q+ + +C+ + +
Sbjct: 1327 EGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATA 1386
Query: 499 LDNEVK--TLRQHLE-LQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLK 554
D E + LR+ +E L K + + Q + + A+L++++ + +L+ E+ ++ K
Sbjct: 1387 TDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELE--EQLSQHRGCAK 1444
Query: 555 ENNIVDSFNKQI------LRIEEQHKLEINVLEEKQREEI--KLYRL--QLAQAAE 600
+ V + +Q+ LR + Q E E +REE ++ RL QL QAA+
Sbjct: 1445 QAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAK 1500
>U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein.
Length = 725
Score = 52.0 bits (119), Expect = 6e-06
Identities = 65/275 (23%), Positives = 119/275 (43%), Gaps = 14/275 (5%)
Query: 350 SELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVM 409
+EL K+ + Q + L E L + T++ + + ++ V + + +
Sbjct: 148 NELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ 207
Query: 410 RLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVN 469
QL + ++E+ EK + I E++ V L + Q + LK K +
Sbjct: 208 GKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKND 267
Query: 470 EERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE----VKTLRQHLELQKNELKCHYQKQ- 524
E S +E + Q ++ KC L+ E V R+H E E++ QK
Sbjct: 268 EILSLKQSLEDNIVILSKQVEDLNVKCQLLETEKEDHVNRNREHNENLNAEMQNLEQKFI 327
Query: 525 LEDAVLAKLQEFQEQLD---RAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE 581
LE KLQ+ + Q+D + E+E+ + K + + K+ EE+ K ++ L+
Sbjct: 328 LEQREHEKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELD 387
Query: 582 EKQREEIKLYRL--QLAQ----AAEKLGLLESKVE 610
+ Q++E + RL QL + AE+L LLE K++
Sbjct: 388 KLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLK 422
Score = 50.4 bits (115), Expect = 2e-05
Identities = 73/342 (21%), Positives = 145/342 (42%), Gaps = 24/342 (7%)
Query: 318 DRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE 377
+R+R+ E + E++N Q++ + + + L ++ L + S +
Sbjct: 306 NRNREHNENLNAEMQNLEQKFILEQREHEKLQQKELQIDSLLQQEKELSSSLHQKLCSFQ 365
Query: 378 EQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKN-------LEE------ 424
E++ E + L E+D L++ + RL KQL + K+ LEE
Sbjct: 366 EEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKE 425
Query: 425 -ALEKEKFAHDSTKSNITE-LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQL 482
LEK AH + E + +QS+ D T + L S++ + + + ++++
Sbjct: 426 AELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKA 485
Query: 483 CEKQNQCSEVLKKCDFLD-NEVKTLRQHLELQ-KNELKCHYQKQLEDAVLAKLQEFQEQL 540
+ +V + + + + +R L+LQ K+ LK K++ + L K+ + Q QL
Sbjct: 486 AKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQL 545
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL-AQAA 599
+ E + +E + N EE +K + L E+ + K ++LQL A
Sbjct: 546 KQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRL--LYEELYNKTKPFQLQLDAFEV 603
Query: 600 EKLGLLESKVECQRR--RRGETAARL--HAALQAHWRHALRI 637
EK LL Q + + ++ A+L H L+ +H +++
Sbjct: 604 EKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKL 645
Score = 45.2 bits (102), Expect = 7e-04
Identities = 49/244 (20%), Positives = 115/244 (47%), Gaps = 15/244 (6%)
Query: 395 DKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDET 454
DK++ +L++ +++ +++LE LEK + ++ T L+ ++ +
Sbjct: 82 DKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQL 141
Query: 455 LLLTQERDLLKSKVNE--ERSRCAVIEQQLCEKQN----QCSEVLKKCDFLDNEVKTLRQ 508
+ LT+ +LLKSK +E + ++ +L + +N + ++ K + ++ +++ ++
Sbjct: 142 IELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQR 201
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLK-ENNIVDSFNKQIL 567
LE + ++ QLE +++ +E ++ E+ +E + ++ V+ + I
Sbjct: 202 SLEESQGKI-----AQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIA 256
Query: 568 RIEEQHKL---EINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLH 624
++EE K EI L++ + I + Q+ K LLE++ E R E L+
Sbjct: 257 QLEENLKEKNDEILSLKQSLEDNIVILSKQVEDLNVKCQLLETEKEDHVNRNREHNENLN 316
Query: 625 AALQ 628
A +Q
Sbjct: 317 AEMQ 320
Score = 37.5 bits (83), Expect = 0.15
Identities = 58/281 (20%), Positives = 116/281 (41%), Gaps = 22/281 (7%)
Query: 332 ENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK-------KSLEEQLNTEL 384
EN + D+ E + D KC+ L+ EK + E LN E+
Sbjct: 260 ENLKEKNDEILSLKQSLEDNIVILSKQVEDLNVKCQLLETEKEDHVNRNREHNENLNAEM 319
Query: 385 DNVNVMLSNKDKEIDVLKE---NYDTVMRLNKQLTDCVK----NLEEALEKEK-FAHDST 436
N+ + +E + L++ D++++ K+L+ + + +E + KEK +
Sbjct: 320 QNLEQKFILEQREHEKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEEL 379
Query: 437 KSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKC 496
K + EL+K Q L+ Q + KS+ E + ++ + E + + +
Sbjct: 380 KQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQAT 439
Query: 497 DFLDNEVKTLRQHLE---LQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARL 553
L + ++ Q LE Q K ++ED L QE+ +A + E D +
Sbjct: 440 LLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN-SSLQEKAAKAGKNAE-DVQ- 496
Query: 554 KENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQ 594
+ +S N++ +R+ + + + L+E + +EI + LQ
Sbjct: 497 HQILATESSNQEYVRMLLDLQTK-SALKETEIKEITVSFLQ 536
>M75165-1|AAB59509.1| 284|Homo sapiens tropomyosin protein.
Length = 284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
Score = 35.1 bits (77), Expect = 0.80
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 30/188 (15%)
Query: 287 VAMKVDRAKD---AAISKLREAWLRLTNS---LDRAEDRHRKALEKMICE---VENFRVV 337
V ++DRA++ A+ KL EA S + E+R K EKM + ++ + +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 338 ADDAQKKTSH-------FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVM 390
A+D+ +K E EL ++ + A + + +QL+ E +++++ L + + +
Sbjct: 155 AEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
Query: 391 LSNKDK---EIDVLKENYD-----------TVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+ +DK EI +L+E +V +L K + D + L A E+ H +
Sbjct: 215 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Query: 437 KSNITELN 444
+ ELN
Sbjct: 275 DQTLLELN 282
>M74817-1|AAA61230.1| 284|Homo sapiens tropomyosin-1 protein.
Length = 284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
Score = 35.1 bits (77), Expect = 0.80
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 30/188 (15%)
Query: 287 VAMKVDRAKD---AAISKLREAWLRLTNS---LDRAEDRHRKALEKMICE---VENFRVV 337
V ++DRA++ A+ KL EA S + E+R K EKM + ++ + +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 338 ADDAQKKTSH-------FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVM 390
A+D+ +K E EL ++ + A + + +QL+ E +++++ L + + +
Sbjct: 155 AEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
Query: 391 LSNKDK---EIDVLKENYD-----------TVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+ +DK EI +L+E +V +L K + D + L A E+ H +
Sbjct: 215 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Query: 437 KSNITELN 444
+ ELN
Sbjct: 275 DQTLLELN 282
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/302 (20%), Positives = 139/302 (46%), Gaps = 25/302 (8%)
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLE--EQLNT 382
++M E F+ D+ K + + K + L + D Q+Q+E SL E+
Sbjct: 850 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCE 909
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L + L K KE+ E + + N +LT + LE+ + K D + + +
Sbjct: 910 QLIKNKIQLEAKIKEVTERAEEEEEI---NAELTAKKRKLEDECSELKKDIDDLELTLAK 966
Query: 443 LNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNE 502
+ K+ + ++ LT+E + ++E ++ + ++ L E Q + L+ + N
Sbjct: 967 VEKQKHATENKVKNLTEEM----AGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 503 VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSF 562
+ + LE Q ++L+ +++ ++ + L+RA+R++E D +L + + +D
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQE---------KKLRMDLERAKRKLEGDLKLAQESTMDME 1073
Query: 563 NKQILRIEEQHKLE------INVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
N + E+ K E I+ +E++Q EI+L + ++ + ++ L ++E +R R
Sbjct: 1074 NDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQK-KIKELQARIEELGEEIEAERASR 1132
Query: 617 GE 618
+
Sbjct: 1133 AK 1134
Score = 45.2 bits (102), Expect = 7e-04
Identities = 61/301 (20%), Positives = 127/301 (42%), Gaps = 26/301 (8%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQN 371
+LD+ + K L + + E + + +QK++ +EL+K ++ + D+ + L+
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRR 1503
Query: 372 EKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKF 431
K+L++ E+ ++ ++ K+I L+ ++ KQ+ ++ ALE+ +
Sbjct: 1504 AHKNLQQ----EISDLTEQIAEGGKQIHELE-------KIKKQVEQEKCEIQAALEEAEA 1552
Query: 432 AHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE----KQN 487
+ + + I + + V E E+D ++ +R Q + +N
Sbjct: 1553 SLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRN 1612
Query: 488 QCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREM 547
V KK + NE++ H E +Y+ L+E Q LD A R
Sbjct: 1613 DALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRN-----TQGILKETQLHLDDALRGQ 1667
Query: 548 ENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLES 607
E+ LKE + +L+ E + LE+ +R K+ +L A+E++ LL +
Sbjct: 1668 ED---LKEQLAIVERRANLLQAEIEELWA--TLEQTERSR-KIAEQELLDASERVQLLHT 1721
Query: 608 K 608
+
Sbjct: 1722 Q 1722
Score = 38.7 bits (86), Expect = 0.065
Identities = 58/341 (17%), Positives = 150/341 (43%), Gaps = 19/341 (5%)
Query: 302 LREAWLRLTNSLDRAEDRHR---KALEKMICEVENFRVVADDAQKKTSHFESELYKTLDL 358
L+E + + L ED+ KA K+ +V++ + +K E K
Sbjct: 1002 LQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGD 1061
Query: 359 AHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDC 418
Q+ ++N+K+ L+E+L + ++ ++S + E V + + L ++ +
Sbjct: 1062 LKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEEL 1121
Query: 419 VKNLE----EALEKEKFAHDSTKSNITELNKRIQSVNDET---LLLTQERDLLKSKVNEE 471
+ +E + EK D ++ + E+++R++ T + L ++R+ K+ +
Sbjct: 1122 GEEIEAERASRAKAEKQRSDLSR-ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRD 1180
Query: 472 RSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA- 528
+ + + ++ + + + +DN ++ ++Q LE +K+ELK +A
Sbjct: 1181 LEEATLQHEAMVAALRKKHADSMAELGEQIDN-LQRVKQKLEKEKSELKMETDDLSSNAE 1239
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKE---NNIVDSFNKQILRIEEQHKLEINVLEEKQR 585
++K + E++ R+ + + + KE +++ Q R++ + L+E+
Sbjct: 1240 AISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDA 1299
Query: 586 EEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAA 626
+L R + A + +++ L+ ++E + + + A L ++
Sbjct: 1300 LVSQLSRSKQA-STQQIEELKHQLEEETKAKNALAHALQSS 1339
Score = 34.7 bits (76), Expect = 1.1
Identities = 43/244 (17%), Positives = 108/244 (44%), Gaps = 17/244 (6%)
Query: 291 VDRAKDAAISKLREAWLRLTN---SLDRAEDRHRKALEKM-ICEVENFRVV--ADDAQKK 344
V+R + +++ E W L S AE A E++ + +N ++ +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEND 1736
Query: 345 TSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELD---NVNVMLSNKDKEIDVL 401
S +SE+ + + + + ++K K+ + + E+L E D ++ M N ++ + L
Sbjct: 1737 VSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1796
Query: 402 KENYDTVMRL-----NKQLTDC---VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDE 453
+ D +L KQ+ V+ LE +E E+ + + + ++R++ + +
Sbjct: 1797 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKELTYQ 1856
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
T + L+ V++ +++ ++Q E + Q + L K L +E++ + ++
Sbjct: 1857 TEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIA 1916
Query: 514 KNEL 517
++++
Sbjct: 1917 ESQV 1920
Score = 33.9 bits (74), Expect = 1.8
Identities = 65/329 (19%), Positives = 131/329 (39%), Gaps = 48/329 (14%)
Query: 358 LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTD 417
L+ Q +Q++ K LEE+ + + + S++ + D+L+E Y+ +L
Sbjct: 1304 LSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH-DCDLLREQYEEEQEGKAELQR 1362
Query: 418 CVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAV 477
+ + + + ++ T+ +R + + + L Q + V ++CA
Sbjct: 1363 ALSKANSEVAQWRTKYE------TDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCAS 1416
Query: 478 IEQQLCEKQNQ--------------CSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQ- 522
+E+ QN+ C+ + KK D + +Q E + EL+ +
Sbjct: 1417 LEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKE 1476
Query: 523 -KQLEDAVLAKLQEFQEQLDRAE--REMENDARLKENNIVDSF---NKQILRIE------ 570
+ L + ++E LD+ E R + + + +++ + KQI +E
Sbjct: 1477 SRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 571 EQHKLEIN-VLEEK----QREEIKLYRLQL------AQAAEKLGLLESKVECQRRRRGET 619
EQ K EI LEE + EE K+ R+QL ++ K+ + +++ +R
Sbjct: 1537 EQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRV 1596
Query: 620 AARLHAALQAHWR---HALRILAAPHHDL 645
+ + L A R ALR+ DL
Sbjct: 1597 VETMQSTLDAEIRSRNDALRVKKKMEGDL 1625
>M12125-1|AAA36773.1| 284|Homo sapiens protein ( Human fibroblast
muscle-type tropomyosin mRNA, complete cds. ).
Length = 284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
Score = 35.1 bits (77), Expect = 0.80
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 30/188 (15%)
Query: 287 VAMKVDRAKD---AAISKLREAWLRLTNS---LDRAEDRHRKALEKMICE---VENFRVV 337
V ++DRA++ A+ KL EA S + E+R K EKM + ++ + +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 338 ADDAQKKTSH-------FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVM 390
A+D+ +K E EL ++ + A + + +QL+ E +++++ L + + +
Sbjct: 155 AEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
Query: 391 LSNKDK---EIDVLKENYD-----------TVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+ +DK EI +L+E +V +L K + D + L A E+ H +
Sbjct: 215 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Query: 437 KSNITELN 444
+ ELN
Sbjct: 275 DQTLLELN 282
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 52.0 bits (119), Expect = 6e-06
Identities = 54/276 (19%), Positives = 127/276 (46%), Gaps = 10/276 (3%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ EL KT + ++K L EK L+ Q+ E D+ L++ ++ D L + +
Sbjct: 864 KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADS----LADAEERCDQLIKTKIQL 919
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
K++T+ ++ EE + + +EL K I + + +E+ ++KV
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCHYQKQLED 527
A +++ + + + + + ++++ + L K ++K Q +
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1039
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLEINVLEEKQR 585
L + ++ + L+RA+R++E D +L + + +D N +Q+ ++ + E++ L+ K
Sbjct: 1040 GSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIE 1099
Query: 586 EEIKL-YRLQ--LAQAAEKLGLLESKVECQRRRRGE 618
+E L +LQ + + ++ LE ++E +R R +
Sbjct: 1100 DEQALGMQLQKKIKELQARIEELEEEIEAERASRAK 1135
Score = 49.6 bits (113), Expect = 3e-05
Identities = 63/308 (20%), Positives = 133/308 (43%), Gaps = 32/308 (10%)
Query: 310 TNSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDK 365
TN+ A D+ ++ +K++ E E + +QK++ +EL+K + + D+
Sbjct: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
Query: 366 CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA 425
+ L+ E K+L++ E+ ++ ++ K I LK ++ KQ+ L+ A
Sbjct: 1499 LETLKRENKNLQQ----EISDLTEQIAEGGKRIHELK-------KIKKQVEQEKSELQAA 1547
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-----LLKSKVNEERSRCAVIEQ 480
LE+ + + + + I + + V E E+D + ++ + S + ++
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
++ +N + KK + NE++ H E +Y+ A L++ Q L
Sbjct: 1608 EI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN-----TQAILKDTQLHL 1661
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
D A R E+ LKE + +L+ E + E+ E+ K+ +L A+E
Sbjct: 1662 DDALRSQED---LKEQLAMVERRANLLQAEIE---ELRATLEQTERSRKIAEQELLDASE 1715
Query: 601 KLGLLESK 608
++ LL ++
Sbjct: 1716 RVQLLHTQ 1723
Score = 40.7 bits (91), Expect = 0.016
Identities = 39/192 (20%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 392 SNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK---SNITELNKRIQ 448
S EID L N +TV + L + LE+ L + K + + +++T R+Q
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 449 SVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
+ + E E+D L S+++ + QQ+ E + Q E +K L + +++ R
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQ---AFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
+L + + + + + E + + + ++ + + E DA + + ++ K R
Sbjct: 1343 DCDLLREQYEEEQEAKAE--LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 569 IE--EQHKLEIN 578
++ E+H +N
Sbjct: 1401 LQDAEEHVEAVN 1412
Score = 38.7 bits (86), Expect = 0.065
Identities = 57/258 (22%), Positives = 103/258 (39%), Gaps = 25/258 (9%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E E+ LAH Q ++ EE+ + + M S + E+ + Y+T
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM-SKANSEVAQWRTKYET- 1381
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+ LEEA +K + ++ +N + S+ L E + L V
Sbjct: 1382 -----DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDV 1436
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQKQL 525
+ CA ++++ +E +KC+ E++ ++ L + ++K Y++ L
Sbjct: 1437 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESL 1496
Query: 526 EDAVLAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN-VLE 581
+ K + QE D E+ E R+ E + KQ+ EQ K E+ LE
Sbjct: 1497 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHE---LKKIKKQV----EQEKSELQAALE 1549
Query: 582 EK----QREEIKLYRLQL 595
E + EE K+ R+QL
Sbjct: 1550 EAEASLEHEEGKILRIQL 1567
Score = 37.5 bits (83), Expect = 0.15
Identities = 49/311 (15%), Positives = 129/311 (41%), Gaps = 30/311 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++ L+ + E + + +++ E L + +
Sbjct: 989 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKI 1048
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E + + ++ L K+ E+ L+ + L QL
Sbjct: 1049 RMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQL 1108
Query: 416 TDCVKNL-------EEALEKEKFAHDSTKSNITELNKRIQSVNDE----------TLLLT 458
+K L EE +E E+ + + ++L++ ++ +++ + +
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1168
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1227
Query: 517 LKCHYQKQLED-AVLAKLQEFQEQLDRAEREMENDARLKE---NNIVDSFNKQILRIEEQ 572
+K + ++K + E++ RA + ++ + KE +++ Q R++ +
Sbjct: 1228 MKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
Query: 573 HKLEINVLEEK 583
L+EK
Sbjct: 1288 SGEYSRQLDEK 1298
Score = 37.5 bits (83), Expect = 0.15
Identities = 37/245 (15%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 305 AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
A + + + + R+ LE+ + E A +KK + +EL + +D +
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHE---ATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K ++ ++E K + L + ++ V+ N +K L++ + ++ + +L
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTA 1279
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
+ + + E + + ++ TQ+ + LK ++ EE + + L
Sbjct: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE 544
++ C ++L++ + E K Q + N ++ + E + + +E +E +
Sbjct: 1340 SRHDC-DLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
Query: 545 REMEN 549
+ +++
Sbjct: 1399 QRLQD 1403
>BC011776-1|AAH11776.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
Score = 35.1 bits (77), Expect = 0.80
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 30/188 (15%)
Query: 287 VAMKVDRAKD---AAISKLREAWLRLTNS---LDRAEDRHRKALEKMICE---VENFRVV 337
V ++DRA++ A+ KL EA S + E+R K EKM + ++ + +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 338 ADDAQKKTSH-------FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVM 390
A+D+ +K E EL ++ + A + + +QL+ E +++++ L + + +
Sbjct: 155 AEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
Query: 391 LSNKDK---EIDVLKENYD-----------TVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+ +DK EI +L+E +V +L K + D + L A E+ H +
Sbjct: 215 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Query: 437 KSNITELN 444
+ ELN
Sbjct: 275 DQTLLELN 282
>AL137068-4|CAI12357.1| 994|Homo sapiens centrosomal protein 110kDa
protein.
Length = 994
Score = 52.0 bits (119), Expect = 6e-06
Identities = 76/317 (23%), Positives = 136/317 (42%), Gaps = 22/317 (6%)
Query: 300 SKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLA 359
S+L E R+ + +D + E I E + D + S + L A
Sbjct: 24 SRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALK---KDLEGVISGLQEYLGTIKGQA 80
Query: 360 HDYQDKCKQLQNEKKSL------EEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNK 413
Q++C++L++EK++L EQ +L+ V + N KE+ L+ +N
Sbjct: 81 TQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNA 140
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERS 473
L +L A E E A + + E N+ + + T L E+ L++++ +ER
Sbjct: 141 SLQQTQGDL-SAYEAELEARLNLRD--AEANQLKEELEKVTRLTQLEQSALQAELEKERQ 197
Query: 474 --RCAVIEQQLC-EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQL--EDA 528
+ A+ + Q EK+ + SE+ K L ++ L+Q L+ +N L H L +
Sbjct: 198 ALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLN-HVVDGLVRPEE 256
Query: 529 VLAKLQEFQEQLDRAEREME----NDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQ 584
V A++ E + +L EM +D K + +IL + + E V E K
Sbjct: 257 VAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKL 316
Query: 585 REEIKLYRLQLAQAAEK 601
+EE+ L + +LA E+
Sbjct: 317 QEEMALQQEKLATGQEE 333
Score = 39.1 bits (87), Expect = 0.049
Identities = 72/350 (20%), Positives = 142/350 (40%), Gaps = 35/350 (10%)
Query: 295 KDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK 354
+DA ++L+E ++T + + LEK ++N A +++K SEL+
Sbjct: 163 RDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQE-NSELHA 221
Query: 355 TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKEN---------- 404
L QD L+ + K + LN +D + V +D L+
Sbjct: 222 KLK---HLQDDNNLLKQQLKDFQNHLNHVVDGL-VRPEEVAARVDELRRKLKLGTGEMNI 277
Query: 405 YDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQER--- 461
+ L K L D K E L + K+ D + +L + + ++ E L QE
Sbjct: 278 HSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEM-ALQQEKLATGQEEFRQ 336
Query: 462 ---DLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNEL- 517
L++++N ++ + QQ+ + + E LK + + Q + +K +
Sbjct: 337 ACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERIL 396
Query: 518 ----KCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
+ +K+LEDA K QE LD+ ++++ + +++ H
Sbjct: 397 AQLRELEKKKKLEDA---KSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLH 453
Query: 574 KLEINVLEEKQRE--EIKLYRLQLAQAAEKLGLLESKVECQR---RRRGE 618
+ + +E+ E E + + + AQAA L E+++E + R++GE
Sbjct: 454 GTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGE 503
Score = 37.5 bits (83), Expect = 0.15
Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 16/157 (10%)
Query: 445 KRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVK 504
+++ +N + L D + S++ +E +E+QL E Q +E LKK L+ +
Sbjct: 10 QQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKK--DLEGVIS 67
Query: 505 TLRQHLELQKNEL-----KCHYQKQLEDAVLAKLQEFQEQLDRAE-REMENDARLKENNI 558
L+++L K + +C + ++ +L +L E +++ D+ E M+ + KE
Sbjct: 68 GLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAE 127
Query: 559 VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQL 595
++S ++EQH E+N ++ + ++ Y +L
Sbjct: 128 LES------ALQEQH--EVNASLQQTQGDLSAYEAEL 156
Score = 35.5 bits (78), Expect = 0.60
Identities = 43/233 (18%), Positives = 103/233 (44%), Gaps = 10/233 (4%)
Query: 360 HDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCV 419
H+ +++ +L++ + L+ + E + +KE++ L N D +++ K L V
Sbjct: 767 HNLENEVSRLEDIMQHLKSKKREERW-MRASKRQSEKEMEELHHNIDDLLQEKKSLECEV 825
Query: 420 KNLEEALEKEK----FAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRC 475
+ L ++K + F + +S +TEL + E ++ E + ++ + + RS
Sbjct: 826 EELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIV--DEIECIEKTLLKRRSEL 883
Query: 476 AVIEQQLCEKQNQCSEVLKKC-DFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQ 534
++ L E +++ S +K + ++ R L+ + + + + Q L K
Sbjct: 884 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 943
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
+ L +++E ++K+ I+ NK I+ ++ ++ +EK EE
Sbjct: 944 QQLRSLQADAKDLEQH-KIKQEEILKEINK-IVAAKDSDFQCLSKKKEKLTEE 994
>AL133410-2|CAI10974.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
Score = 35.1 bits (77), Expect = 0.80
Identities = 44/188 (23%), Positives = 85/188 (45%), Gaps = 30/188 (15%)
Query: 287 VAMKVDRAKD---AAISKLREAWLRLTNS---LDRAEDRHRKALEKMICE---VENFRVV 337
V ++DRA++ A+ KL EA S + E+R K EKM + ++ + +
Sbjct: 95 VEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHI 154
Query: 338 ADDAQKKTSH-------FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVM 390
A+D+ +K E EL ++ + A + + +QL+ E +++++ L + + +
Sbjct: 155 AEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEY 214
Query: 391 LSNKDK---EIDVLKENYD-----------TVMRLNKQLTDCVKNLEEALEKEKFAHDST 436
+ +DK EI +L+E +V +L K + D + L A E+ H +
Sbjct: 215 STKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Query: 437 KSNITELN 444
+ ELN
Sbjct: 275 DQTLLELN 282
>AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens
cDNA FLJ16459 fis, clone BRCAN2002473, moderately
similar to Tropomyosin, fibroblast isoform 2. ).
Length = 326
Score = 52.0 bits (119), Expect = 6e-06
Identities = 53/257 (20%), Positives = 110/257 (42%), Gaps = 11/257 (4%)
Query: 363 QDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNL 422
+D+ KQL+ + + E+ L D + +L K D L + +L +L K L
Sbjct: 33 EDRSKQLEEDIAAKEKLLRVSEDERDRVLEELHKAEDSLLAAEEAAAKLEDELVSLQKKL 92
Query: 423 ---EEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIE 479
E+ L+K A + + K+ + L + L++ +++ + R A
Sbjct: 93 KGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATAL 152
Query: 480 QQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQ 534
Q+L E + E + +++ + + +E+Q+ +LK H + + + V KL
Sbjct: 153 QKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLV 212
Query: 535 EFQEQLDRAEREME-NDARLKE-NNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYR 592
+ L+RAE E ++ + E + + + +E Q + + + E++ EEIK+
Sbjct: 213 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAE-KYSQKEDRYEEEIKVLS 271
Query: 593 LQLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 272 DKLKEAETRAEFAERSV 288
Score = 33.1 bits (72), Expect = 3.2
Identities = 35/173 (20%), Positives = 73/173 (42%), Gaps = 9/173 (5%)
Query: 296 DAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYK- 354
+A ++ L + LDRA++R AL+K+ E AD++++ ES K
Sbjct: 124 EADVASLNRRIQLVEEELDRAQERLATALQKL----EEAEKAADESERGMKVIESRAQKD 179
Query: 355 --TLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLN 412
+++ + K + + E++ +L + L ++ ++ + +
Sbjct: 180 EEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL 239
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLK 465
K +T+ +K+LE EK D + I L+ +++ ET ER + K
Sbjct: 240 KTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEA--ETRAEFAERSVTK 290
>AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein.
Length = 3336
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 15/251 (5%)
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE---RDLLKSKVNE 470
QL V+ L +E+EK + ++E ++ SV + LL ++ RDL KS + E
Sbjct: 2559 QLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSV--QKLLAAEQTVVRDL-KSDLCE 2615
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
R + + + LCE Q + ++ +NE+K Q LE ++ + + Q QLE+ L
Sbjct: 2616 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRA-LQSQLEEEQL 2674
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
LQ + Q +A E+ A L+ S + + ++ + + N+ +E + E +
Sbjct: 2675 RHLQR-ESQSAKALEELR--ASLETQRAQSS--RLCVALKHEQTAKDNLQKELRIEHSRC 2729
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGETAARL-HAALQAHWRHALRILAAPHHDLGTHS 649
L LAQ +L L+ + ++ R E + L H L A H D H
Sbjct: 2730 EAL-LAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH- 2787
Query: 650 HSTPSNVSEHK 660
H+ + E K
Sbjct: 2788 HALLQKLKEEK 2798
Score = 44.4 bits (100), Expect = 0.001
Identities = 67/283 (23%), Positives = 116/283 (40%), Gaps = 23/283 (8%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
K Q K +L+++L E +L+ + ++ L++ D ++ L L EAL
Sbjct: 2709 KHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQK--DLAAEKSRTL-----ELSEAL 2761
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
E+ + E + LL + + KS+V + ++ ++QQ Q
Sbjct: 2762 RHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEE--KSRVVDLQAMLEKVQQQALHSQ 2819
Query: 487 NQC-SEVLKKCDFLDNE------VKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
Q +E K C+ L E +K+ + L QK EL+C +++ E + + Q
Sbjct: 2820 QQLEAEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKPAWLQAELEQSH 2879
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRLQLAQA 598
E+E AR + R ++ K ++ LE ++QR+ K+ +LQ
Sbjct: 2880 PRLKEQEGRKAARRSAEARQSPAAAEQWRKWQRDKEKLRELELQRQRDLHKIKQLQ---- 2935
Query: 599 AEKLGLLESKVECQRRRRGETAARLHAALQA-HWRHALRILAA 640
+ + LESK E R +AR A A H R R L A
Sbjct: 2936 -QTVRDLESKDEVPGSRLHLGSARRAAGSDADHLREQQRELEA 2977
Score = 41.5 bits (93), Expect = 0.009
Identities = 74/347 (21%), Positives = 155/347 (44%), Gaps = 27/347 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ--L 369
SLD+ R+ +++ E E+ R ++ Q++ E +L + +Q L
Sbjct: 1469 SLDKHLRNQRQFMDEQAAEREHER---EEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPL 1525
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNK---DKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
E + L+++L +LD N + K D+++ + +E + +N + V L+E +
Sbjct: 1526 DGEVELLQQKLREKLDEFNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEV 1585
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
EK+K + + L K Q ++ L T + L + E S ++ +
Sbjct: 1586 EKQKNIVKGLEQDKEVLKK--QQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEV 1643
Query: 487 NQCSEVLKKCDFLD--NEVKTLRQHLELQKNELKCHYQKQLE---DAVLAKLQEFQEQLD 541
Q + + ++ + LD +++ ++ LE KNE H +L+ L+E +E+
Sbjct: 1644 TQRALLRRESEVLDLKEQLEKMKGDLE-SKNEEILHLNLKLDMQNSQTAVSLRELEEENT 1702
Query: 542 RAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLEINVLE---EKQREEIKLYRLQLAQ 597
+ + ++E +++ + R++++ EI L EK + E+ L + +
Sbjct: 1703 SLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHE 1762
Query: 598 AAE-KLGLLESKVECQRR--RRGET-AARLHAALQAHWRHAL-RILA 639
++ + G L+S++ C + RG+ L AAL+A + AL R+LA
Sbjct: 1763 VSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEA--KEALSRLLA 1807
Score = 39.9 bits (89), Expect = 0.028
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 34/279 (12%)
Query: 351 ELYKTLDLAHDYQDKCKQLQNE---KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
EL+KT ++ + L+ K+ E +L EL+++ L +E L+E
Sbjct: 1329 ELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTR 1388
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
+ + + E AL KE D TK + R Q+ D + LL+Q + +L+S+
Sbjct: 1389 LWSRGEATATDAEAREAALRKE--VEDLTKE---QSETRKQAEKDRSALLSQMK-ILESE 1442
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVL-KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E+ S + + C KQ + L ++ LD ++ RQ ++ Q E + H +++ +
Sbjct: 1443 LEEQLS-----QHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAERE-HEREEFQ 1496
Query: 527 DAV---------LAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIEEQHK 574
+ AK Q + + D + ++ + L + + +D FN+ ++ E +
Sbjct: 1497 QEIQRLEGQLRQAAKPQPWGPR-DSQQAPLDGEVELLQQKLREKLDEFNELAIQKESADR 1555
Query: 575 LEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR 613
VL Q EEIK +K+ L+ +VE Q+
Sbjct: 1556 ---QVL--MQEEEIKRLEEMNINIRKKVAQLQEEVEKQK 1589
Score = 37.5 bits (83), Expect = 0.15
Identities = 63/300 (21%), Positives = 133/300 (44%), Gaps = 15/300 (5%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLN 412
+ L L +++ + LQ E K E L E N+ L ++ + + D+ K ++ +
Sbjct: 669 RVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYEKLQHETRLKDDLEKVKHNLIEDHQ 728
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+L + + E L K++F T + + + ++ TL+L + R+ +S+
Sbjct: 729 KELNNAKQKTE--LMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTII 786
Query: 473 SRCAVIEQQLCEKQNQ-CSEVLKKCDFLDNEVKTLRQ-HLELQKNE-LKCHY-QKQLEDA 528
++ + E ++ + Q+Q +++L L + L+Q +L ++ L C ++ A
Sbjct: 787 NKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCGREPPTA 846
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENN--IVDSFNKQ----ILRIEEQHKLEINVLEE 582
+L + D A + M +R E I + F+ + + +EQH E+ +L+E
Sbjct: 847 QDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQLLQE 906
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALRILAAPH 642
+ ++++ +L +A + L E + ++ AAR+ A LQ L L H
Sbjct: 907 RHQQQLLSVTAEL-EARHQAALGELTASLESKQGALLAARV-AELQTKHAADLGALETRH 964
Score = 35.1 bits (77), Expect = 0.80
Identities = 52/236 (22%), Positives = 110/236 (46%), Gaps = 22/236 (9%)
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L+ + S +KE E V+R +++L +C+K EE+ K + A + K+ T
Sbjct: 1280 QLEEARQIHSRFEKEFSFKNEETAQVVRKHQELLECLK--EESAAKAELALELHKTQGTL 1337
Query: 443 LNKRIQSVNDETLLLTQE--RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK--CDF 498
++++ + + +L +E L ++ R + Q+ + +C+ + +
Sbjct: 1338 EGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATA 1397
Query: 499 LDNEVK--TLRQHLE-LQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLK 554
D E + LR+ +E L K + + Q + + A+L++++ + +L+ E+ ++ K
Sbjct: 1398 TDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELE--EQLSQHRGCAK 1455
Query: 555 ENNIVDSFNKQI------LRIEEQHKLEINVLEEKQREEI--KLYRL--QLAQAAE 600
+ V + +Q+ LR + Q E E +REE ++ RL QL QAA+
Sbjct: 1456 QAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAK 1511
Score = 34.3 bits (75), Expect = 1.4
Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 440 ITELNKRIQSVNDETLLLTQER-----DLLKSKVNEERSRCAV-IEQQLCE-KQNQCSEV 492
+TEL + + S + L L Q R +LL+ + E+ + Q+ E K+ SE+
Sbjct: 277 LTELREMLNSRRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEM 336
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR--AEREMEND 550
K VKTL++ E +K+ + +K+L +++++ Q Q + AE+ E +
Sbjct: 337 EKNAQI----VKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELE 392
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
++ N + + + +E H+ I L E + E
Sbjct: 393 KIFQDKNQAE---RALRNLESHHQAAIEKLREDLQSE 426
>AF304450-1|AAG41949.1| 359|Homo sapiens sarcolemmal associated
protein 1 protein.
Length = 359
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/294 (21%), Positives = 131/294 (44%), Gaps = 22/294 (7%)
Query: 340 DAQKKTSHFESELYKTLDLAHDYQDKCKQLQ----NEKKSLEEQLNTELDNVNVMLSNKD 395
+A+++ H EL + +LA + KC +LQ E+K+ Q+ + V+ +
Sbjct: 28 EAKQEIQHLRKELIEAQELARASKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQ 87
Query: 396 K-EIDV--LKENYDTVMRLNK----QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
+ ID L+E D+ + + D + L +A K D+ +++ E K+++
Sbjct: 88 RLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVR 147
Query: 449 SVNDETLLLTQERDL-LKSKVNEERSRCAVIEQQLCEK----QNQCSEVLKKCDFLDNEV 503
+ + E + + S N + RC E Q E+ Q + ++ K+ + L+ E
Sbjct: 148 AELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETEC 207
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ--LDRAEREMEND-ARLKENNIVD 560
+L++ L +EL+ +K+L ++ L+ + L + +E+EN LKE ++ D
Sbjct: 208 HSLKRENVLLSSELQ-RQEKELHNSQKQSLELTSDLSILQMSRKELENQVGSLKEQHLRD 266
Query: 561 SFN-KQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQA-AEKLGLLESKVECQ 612
S + K +L E ++ EK + + +L+ EK + + +C+
Sbjct: 267 SADLKTLLSKAENQAKDVQKEYEKTQTVLSELKLKFEMTEQEKQSITDELKQCK 320
Score = 41.1 bits (92), Expect = 0.012
Identities = 37/163 (22%), Positives = 77/163 (47%), Gaps = 12/163 (7%)
Query: 456 LLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKN 515
LL +ER +++V E + V++ QL ++ + +E L+ + D+E+ + R L ++
Sbjct: 60 LLEEERKAYRNQVEESTKQIQVLQAQL-QRLHIDTENLR--EEKDSEITSTRDELLSARD 116
Query: 516 ELKCHYQKQLEDAVL--AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQH 573
E+ +Q + A + QE+L + E+E + + K+I ++
Sbjct: 117 EILLLHQAAAKVASERDTDIASLQEELKKVRAELE-----RWRKAASEYEKEITSLQNSF 171
Query: 574 KLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRRRR 616
+L E++QREE + +L + ++ LE+ EC +R
Sbjct: 172 QLRCQQCEDQQREEATRLQGELEKLRKEWNALET--ECHSLKR 212
>AF209746-1|AAF17621.1| 257|Homo sapiens beta tropomyosin protein.
Length = 257
Score = 52.0 bits (119), Expect = 6e-06
Identities = 64/256 (25%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 364 DKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE 423
D+ +Q + +KK E++ +L+ L K LK D V + ++ + + + LE
Sbjct: 20 DRAEQAEADKKQAEDRCK-QLEEEQQALQKK------LKGTEDEVEKYSESVKEAQEKLE 72
Query: 424 EALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLC 483
+A EK A D+ ++++ LN+RIQ V +E ++ + R A Q+L
Sbjct: 73 QA---EKKATDA-EADVASLNRRIQLVEEE--------------LDRAQERLATALQKLE 114
Query: 484 EKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK--CHYQKQLE---DAVLAKLQEFQE 538
E + E + ++N + +ELQ+ +LK H + + + V KL +
Sbjct: 115 EAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEG 174
Query: 539 QLDRAERE---MENDARLKENNI--VDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRL 593
+L+R+E E+ AR E + +D K ++ EE++ + E+K EEIKL
Sbjct: 175 ELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTK----EDKYEEEIKLLEE 230
Query: 594 QLAQAAEKLGLLESKV 609
+L +A + E V
Sbjct: 231 KLKEAETRAEFAERSV 246
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 52.0 bits (119), Expect = 6e-06
Identities = 54/276 (19%), Positives = 127/276 (46%), Gaps = 10/276 (3%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
+ EL KT + ++K L EK L+ Q+ E D+ L++ ++ D L + +
Sbjct: 864 KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADS----LADAEERCDQLIKTKIQL 919
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
K++T+ ++ EE + + +EL K I + + +E+ ++KV
Sbjct: 920 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKV 979
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLE-LQKNELKCHYQKQLED 527
A +++ + + + + + ++++ + L K ++K Q +
Sbjct: 980 KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1039
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN--KQILRIEEQHKLEINVLEEKQR 585
L + ++ + L+RA+R++E D +L + + +D N +Q+ ++ + E++ L+ K
Sbjct: 1040 GSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIE 1099
Query: 586 EEIKL-YRLQ--LAQAAEKLGLLESKVECQRRRRGE 618
+E L +LQ + + ++ LE ++E +R R +
Sbjct: 1100 DEQALGMQLQKKIKELQARIEELEEEIEAERASRAK 1135
Score = 48.0 bits (109), Expect = 1e-04
Identities = 62/308 (20%), Positives = 133/308 (43%), Gaps = 32/308 (10%)
Query: 310 TNSLDRAEDRHRKALEKMICE----VENFRVVADDAQKKTSHFESELYKTLDLAHDYQDK 365
TN+ A D+ ++ +K++ E E + +QK++ +EL+K + + D+
Sbjct: 1439 TNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQ 1498
Query: 366 CKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEA 425
+ L+ E K+L++ E+ ++ ++ K I L+ ++ KQ+ L+ A
Sbjct: 1499 LETLKRENKNLQQ----EISDLTEQIAEGGKRIHELE-------KIKKQVEQEKSELQAA 1547
Query: 426 LEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERD-----LLKSKVNEERSRCAVIEQ 480
LE+ + + + + I + + V E E+D + ++ + S + ++
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607
Query: 481 QLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQL 540
++ +N + KK + NE++ H E +Y+ A L++ Q L
Sbjct: 1608 EI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRN-----TQAILKDTQLHL 1661
Query: 541 DRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAE 600
D A R E+ LKE + +L+ E + E+ E+ K+ +L A+E
Sbjct: 1662 DDALRSQED---LKEQLAMVERRANLLQAEIE---ELRATLEQTERSRKIAEQELLDASE 1715
Query: 601 KLGLLESK 608
++ LL ++
Sbjct: 1716 RVQLLHTQ 1723
Score = 40.7 bits (91), Expect = 0.016
Identities = 39/192 (20%), Positives = 85/192 (44%), Gaps = 10/192 (5%)
Query: 392 SNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTK---SNITELNKRIQ 448
S EID L N +TV + L + LE+ L + K + + +++T R+Q
Sbjct: 1226 SEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 449 SVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
+ + E E+D L S+++ + QQ+ E + Q E +K L + +++ R
Sbjct: 1286 TESGEYSRQLDEKDTLVSQLSRGKQ---AFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILR 568
+L + + + + + E + + + ++ + + E DA + + ++ K R
Sbjct: 1343 DCDLLREQYEEEQEAKAE--LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 569 IE--EQHKLEIN 578
++ E+H +N
Sbjct: 1401 LQDAEEHVEAVN 1412
Score = 39.9 bits (89), Expect = 0.028
Identities = 57/258 (22%), Positives = 104/258 (40%), Gaps = 25/258 (9%)
Query: 349 ESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTV 408
E E+ LAH Q ++ EE+ + + M S + E+ + Y+T
Sbjct: 1324 EEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM-SKANSEVAQWRTKYET- 1381
Query: 409 MRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKV 468
+ LEEA +K + ++ +N + S+ L E + L V
Sbjct: 1382 -----DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDV 1436
Query: 469 NEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQH---LELQKNELKCHYQKQL 525
+ CA ++++ +E +KC+ E++ ++ L + ++K Y++ L
Sbjct: 1437 ERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESL 1496
Query: 526 EDAVLAKLQE---FQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEIN-VLE 581
+ K + QE D E+ E R+ E ++ KQ+ EQ K E+ LE
Sbjct: 1497 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHE---LEKIKKQV----EQEKSELQAALE 1549
Query: 582 EK----QREEIKLYRLQL 595
E + EE K+ R+QL
Sbjct: 1550 EAEASLEHEEGKILRIQL 1567
Score = 37.5 bits (83), Expect = 0.15
Identities = 49/311 (15%), Positives = 129/311 (41%), Gaps = 30/311 (9%)
Query: 302 LREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVAD---DAQKKTSHFESELYKTLDL 358
L E +LT ++ H++ L+ + E + + +++ E L + +
Sbjct: 989 LDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKI 1048
Query: 359 AHDYQDKCKQLQNEKKSLEEQ---LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQL 415
D + ++L+ + K +E + + ++ L K+ E+ L+ + L QL
Sbjct: 1049 RMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQL 1108
Query: 416 TDCVKNL-------EEALEKEKFAHDSTKSNITELNKRIQSVNDE----------TLLLT 458
+K L EE +E E+ + + ++L++ ++ +++ + +
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMN 1168
Query: 459 QERDLLKSKVNEERSRCAVIEQQLCE--KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNE 516
++R+ K+ + + + ++ V + + +DN ++ ++Q LE +K+E
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDN-LQRVKQKLEKEKSE 1227
Query: 517 LKCHYQKQLED-AVLAKLQEFQEQLDRAEREMENDARLKE---NNIVDSFNKQILRIEEQ 572
+K + ++K + E++ RA + ++ + KE +++ Q R++ +
Sbjct: 1228 MKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
Query: 573 HKLEINVLEEK 583
L+EK
Sbjct: 1288 SGEYSRQLDEK 1298
Score = 37.5 bits (83), Expect = 0.15
Identities = 37/245 (15%), Positives = 100/245 (40%), Gaps = 4/245 (1%)
Query: 305 AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQD 364
A + + + + R+ LE+ + E A +KK + +EL + +D +
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHE---ATAATLRKKHADSVAELGEQIDNLQRVKQ 1219
Query: 365 KCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEE 424
K ++ ++E K + L + ++ V+ N +K L++ + ++ + +L
Sbjct: 1220 KLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTA 1279
Query: 425 ALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCE 484
+ + + E + + ++ TQ+ + LK ++ EE + + L
Sbjct: 1280 QRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQS 1339
Query: 485 KQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAE 544
++ C ++L++ + E K Q + N ++ + E + + +E +E +
Sbjct: 1340 SRHDC-DLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1398
Query: 545 REMEN 549
+ +++
Sbjct: 1399 QRLQD 1403
>AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein.
Length = 3284
Score = 52.0 bits (119), Expect = 6e-06
Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 15/251 (5%)
Query: 414 QLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQE---RDLLKSKVNE 470
QL V+ L +E+EK + ++E ++ SV + LL ++ RDL KS + E
Sbjct: 2586 QLRRQVELLAYKVEQEKCIAGDLQKTLSEEQEKANSV--QKLLAAEQTVVRDL-KSDLCE 2642
Query: 471 ERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVL 530
R + + + LCE Q + ++ +NE+K Q LE ++ + + Q QLE+ L
Sbjct: 2643 SRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRA-LQSQLEEEQL 2701
Query: 531 AKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKL 590
LQ + Q +A E+ A L+ S + + ++ + + N+ +E + E +
Sbjct: 2702 RHLQR-ESQSAKALEELR--ASLETQRAQSS--RLCVALKHEQTAKDNLQKELRIEHSRC 2756
Query: 591 YRLQLAQAAEKLGLLESKVECQRRRRGETAARL-HAALQAHWRHALRILAAPHHDLGTHS 649
L LAQ +L L+ + ++ R E + L H L A H D H
Sbjct: 2757 EAL-LAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAH- 2814
Query: 650 HSTPSNVSEHK 660
H+ + E K
Sbjct: 2815 HALLQKLKEEK 2825
Score = 41.5 bits (93), Expect = 0.009
Identities = 74/347 (21%), Positives = 155/347 (44%), Gaps = 27/347 (7%)
Query: 312 SLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQ--L 369
SLD+ R+ +++ E E+ R ++ Q++ E +L + +Q L
Sbjct: 1496 SLDKHLRNQRQFMDEQAAEREHER---EEFQQEIQRLEGQLRQAAKPQPWGPRDSQQAPL 1552
Query: 370 QNEKKSLEEQLNTELDNVNVMLSNK---DKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
E + L+++L +LD N + K D+++ + +E + +N + V L+E +
Sbjct: 1553 DGEVELLQQKLREKLDEFNELAIQKESADRQVLMQEEEIKRLEEMNINIRKKVAQLQEEV 1612
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
EK+K + + L K Q ++ L T + L + E S ++ +
Sbjct: 1613 EKQKNIVKGLEQDKEVLKK--QQMSSLLLASTLQSTLDAGRCPEPPSGSPPEGPEIQLEV 1670
Query: 487 NQCSEVLKKCDFLD--NEVKTLRQHLELQKNELKCHYQKQLE---DAVLAKLQEFQEQLD 541
Q + + ++ + LD +++ ++ LE KNE H +L+ L+E +E+
Sbjct: 1671 TQRALLRRESEVLDLKEQLEKMKGDLE-SKNEEILHLNLKLDMQNSQTAVSLRELEEENT 1729
Query: 542 RAEREMENDARLKE-NNIVDSFNKQILRIEEQHKLEINVLE---EKQREEIKLYRLQLAQ 597
+ + ++E +++ + R++++ EI L EK + E+ L + +
Sbjct: 1730 SLKVIYTRSSEIEELKATIENLQENQKRLQKEKAEEIEQLHEVIEKLQHELSLMGPVVHE 1789
Query: 598 AAE-KLGLLESKVECQRR--RRGET-AARLHAALQAHWRHAL-RILA 639
++ + G L+S++ C + RG+ L AAL+A + AL R+LA
Sbjct: 1790 VSDSQAGSLQSELLCSQAGGPRGQALQGELEAALEA--KEALSRLLA 1834
Score = 39.9 bits (89), Expect = 0.028
Identities = 64/279 (22%), Positives = 122/279 (43%), Gaps = 34/279 (12%)
Query: 351 ELYKTLDLAHDYQDKCKQLQNE---KKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
EL+KT ++ + L+ K+ E +L EL+++ L +E L+E
Sbjct: 1356 ELHKTQGTLEGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTR 1415
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
+ + + E AL KE D TK + R Q+ D + LL+Q + +L+S+
Sbjct: 1416 LWSRGEATATDAEAREAALRKE--VEDLTKE---QSETRKQAEKDRSALLSQMK-ILESE 1469
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVL-KKCDFLDNEVKTLRQHLELQKNELKCHYQKQLE 526
+ E+ S + + C KQ + L ++ LD ++ RQ ++ Q E + H +++ +
Sbjct: 1470 LEEQLS-----QHRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAERE-HEREEFQ 1523
Query: 527 DAV---------LAKLQEFQEQLDRAEREMENDARLKENNI---VDSFNKQILRIEEQHK 574
+ AK Q + + D + ++ + L + + +D FN+ ++ E +
Sbjct: 1524 QEIQRLEGQLRQAAKPQPWGPR-DSQQAPLDGEVELLQQKLREKLDEFNELAIQKESADR 1582
Query: 575 LEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQR 613
VL Q EEIK +K+ L+ +VE Q+
Sbjct: 1583 ---QVL--MQEEEIKRLEEMNINIRKKVAQLQEEVEKQK 1616
Score = 37.5 bits (83), Expect = 0.15
Identities = 63/300 (21%), Positives = 133/300 (44%), Gaps = 15/300 (5%)
Query: 354 KTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDK-EIDVLKENYDTVMRLN 412
+ L L +++ + LQ E K E L E N+ L ++ + + D+ K ++ +
Sbjct: 696 RVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYEKLQHETRLKDDLEKVKHNLIEDHQ 755
Query: 413 KQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEER 472
K+L + + E L K++F T + + + ++ TL+L + R+ +S+
Sbjct: 756 KELNNAKQKTE--LMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTII 813
Query: 473 SRCAVIEQQLCEKQNQ-CSEVLKKCDFLDNEVKTLRQ-HLELQKNE-LKCHY-QKQLEDA 528
++ + E ++ + Q+Q +++L L + L+Q +L ++ L C ++ A
Sbjct: 814 NKFELREAEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCGREPPTA 873
Query: 529 VLAKLQEFQEQLDRAEREMENDARLKENN--IVDSFNKQ----ILRIEEQHKLEINVLEE 582
+L + D A + M +R E I + F+ + + +EQH E+ +L+E
Sbjct: 874 QDGELAALHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQLLQE 933
Query: 583 KQREEIKLYRLQLAQAAEKLGLLESKVECQRRRRGETAARLHAALQAHWRHALRILAAPH 642
+ ++++ +L +A + L E + ++ AAR+ A LQ L L H
Sbjct: 934 RHQQQLLSVTAEL-EARHQAALGELTASLESKQGALLAARV-AELQTKHAADLGALETRH 991
Score = 35.1 bits (77), Expect = 0.80
Identities = 52/236 (22%), Positives = 110/236 (46%), Gaps = 22/236 (9%)
Query: 383 ELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITE 442
+L+ + S +KE E V+R +++L +C+K EE+ K + A + K+ T
Sbjct: 1307 QLEEARQIHSRFEKEFSFKNEETAQVVRKHQELLECLK--EESAAKAELALELHKTQGTL 1364
Query: 443 LNKRIQSVNDETLLLTQE--RDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKK--CDF 498
++++ + + +L +E L ++ R + Q+ + +C+ + +
Sbjct: 1365 EGFKVETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATA 1424
Query: 499 LDNEVK--TLRQHLE-LQKNELKCHYQKQLE-DAVLAKLQEFQEQLDRAEREMENDARLK 554
D E + LR+ +E L K + + Q + + A+L++++ + +L+ E+ ++ K
Sbjct: 1425 TDAEAREAALRKEVEDLTKEQSETRKQAEKDRSALLSQMKILESELE--EQLSQHRGCAK 1482
Query: 555 ENNIVDSFNKQI------LRIEEQHKLEINVLEEKQREEI--KLYRL--QLAQAAE 600
+ V + +Q+ LR + Q E E +REE ++ RL QL QAA+
Sbjct: 1483 QAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQEIQRLEGQLRQAAK 1538
Score = 34.3 bits (75), Expect = 1.4
Identities = 37/157 (23%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 440 ITELNKRIQSVNDETLLLTQER-----DLLKSKVNEERSRCAV-IEQQLCE-KQNQCSEV 492
+TEL + + S + L L Q R +LL+ + E+ + Q+ E K+ SE+
Sbjct: 304 LTELREMLNSRRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQEAAELKEKLQSEM 363
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDR--AEREMEND 550
K VKTL++ E +K+ + +K+L +++++ Q Q + AE+ E +
Sbjct: 364 EKNAQI----VKTLKEDWESEKDLCLENLRKELSAKHQSEMEDLQNQFQKELAEQRAELE 419
Query: 551 ARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
++ N + + + +E H+ I L E + E
Sbjct: 420 KIFQDKNQAE---RALRNLESHHQAAIEKLREDLQSE 453
>U33821-1|AAA75595.2| 747|Homo sapiens tax1-binding protein TXBP151
protein.
Length = 747
Score = 51.6 bits (118), Expect = 9e-06
Identities = 66/324 (20%), Positives = 133/324 (41%), Gaps = 23/324 (7%)
Query: 289 MKVDRAKDAAISKLREAWLRLTNSLDRAEDR--HRKALEKMICEV--------ENFRVVA 338
+K+ + ++LRE R+ L+ ++R +A +K + EV E F+
Sbjct: 165 LKLIAVLEKETAQLREQVGRMERELNHEKERCDQLQAEQKGLTEVTQSLKMENEEFKKRF 224
Query: 339 DDAQKKTSHFESEL----YKTLDLAHDY---QDKCKQLQNEKKSLEEQLNTELDN---VN 388
DA K H E ++ +K ++ + +DK K+ Q+E++ LE QL TE D
Sbjct: 225 SDATSKAHHVEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQLKTEKDEKELYK 284
Query: 389 VMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQ 448
V L N + E L T+ L+ + + +E + + + + K N+
Sbjct: 285 VHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCL-AEKENLQRTFLLTT 343
Query: 449 SVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQ 508
S ++T L ++ + +V R + ++L + N + E + +++
Sbjct: 344 SSKEDTCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRDRTMADLHTARLENEKVKK 403
Query: 509 HLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD--RAEREMENDARLKENNIVDSFNKQI 566
L ELK + K+ +D E + +++ + +M D ++ KQI
Sbjct: 404 QLADAVAELKLNAMKKDQDKTDTLEHELRREVEDLKLRLQMAADHYKEKFKECQRLQKQI 463
Query: 567 LRIEEQHKLEINVLEEKQREEIKL 590
++ +Q NV +K + K+
Sbjct: 464 NKLSDQSANNNNVFTKKTGNQQKV 487
Score = 47.2 bits (107), Expect = 2e-04
Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 14/199 (7%)
Query: 367 KQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEAL 426
K+ Q++ +LE +L E++++ + L D KE + RL KQ + L +
Sbjct: 418 KKDQDKTDTLEHELRREVEDLKLRLQ---MAADHYKEKFKECQRLQKQ----INKLSDQS 470
Query: 427 EKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQ 486
N ++N SVN + D+ S E V + Q+CE
Sbjct: 471 ANNNNVFTKKTGNQQKVNDA--SVNTDPATSASTVDVKPSPSAAEADFDIVTKGQVCEMT 528
Query: 487 NQCS---EVLKKCDFL--DNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLD 541
+ + E KC L D + K + EL K ELK Q ++ + V +L E Q+
Sbjct: 529 KEIADKTEKYNKCKQLLQDEKAKCNKYADELAKMELKWKEQVKIAENVKLELAEVQDNYK 588
Query: 542 RAEREMENDARLKENNIVD 560
+R +EN A K + D
Sbjct: 589 ELKRSLENPAERKMEDGAD 607
Score = 40.7 bits (91), Expect = 0.016
Identities = 70/317 (22%), Positives = 140/317 (44%), Gaps = 33/317 (10%)
Query: 324 LEKMICEVENFRVVADDAQKKTSHFESELYKT-LDLAHDYQDKCKQLQNEKKSLEE---Q 379
+EK + E E + +K+T+ ++ + +L H+ +++C QLQ E+K L E
Sbjct: 154 IEKTMKEKEELLKLIAVLEKETAQLREQVGRMERELNHE-KERCDQLQAEQKGLTEVTQS 212
Query: 380 LNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHD----- 434
L E + S+ + ++E+ +V + + +L++ L+K + +
Sbjct: 213 LKMENEEFKKRFSDATSKAHHVEEDIVSVTHKAIEKETELDSLKDKLKKAQHEREQLECQ 272
Query: 435 -STKSNITELNK-RIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQ-----QLC--EK 485
T+ + EL K +++ E L E LK+ + S ++ QLC EK
Sbjct: 273 LKTEKDEKELYKVHLKNTEIENTKLMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEK 332
Query: 486 QNQCSEVL----KKCD--FLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQ 539
+N L K D FL +++ + ++ + E+ K+L DAV + +
Sbjct: 333 ENLQRTFLLTTSSKEDTCFLKEQLRKAEEQVQATRQEV-VFLAKELSDAVNVR---DRTM 388
Query: 540 LDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAA 599
D +EN+ K+ + D+ + L ++ + + + LE + R E++ +L+L AA
Sbjct: 389 ADLHTARLENEKVKKQ--LADAVAELKLNAMKKDQDKTDTLEHELRREVEDLKLRLQMAA 446
Query: 600 EKLGLLESKVECQRRRR 616
+ E ECQR ++
Sbjct: 447 DH--YKEKFKECQRLQK 461
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 51.6 bits (118), Expect = 9e-06
Identities = 84/374 (22%), Positives = 161/374 (43%), Gaps = 37/374 (9%)
Query: 288 AMKVDRAKDAAISKLRE-AWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS 346
A+KV + AA KLR W R+ + R+ E++ + E V + K
Sbjct: 815 ALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQE-EELQAKDEELLKVKEKQTKVEG 873
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEE------QLNTELDNVNVMLSNKDKEIDV 400
E K L + +QLQ E + E +L + + +L + + ++
Sbjct: 874 ELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEE 933
Query: 401 LKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLL--- 457
+E + K++ +++LEE L++E+ A + +I+ + +E LLL
Sbjct: 934 EEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQ 993
Query: 458 ----TQERDLLKSKVNEERSRCAVIEQQ---LCEKQNQCSEVLKKC-DFLDNEVKTLRQH 509
+E+ L++ ++ E S+ A E++ L + +N+ ++ + L E KT RQ
Sbjct: 994 NSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKT-RQE 1052
Query: 510 LELQKNEL---KCHYQKQLEDAVLAKLQEFQEQLDRAEREME------NDARLKENN--- 557
LE K +L Q Q+ + + A++ E + QL + E E++ +D L +NN
Sbjct: 1053 LEKAKRKLDGETTDLQDQIAE-LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALK 1111
Query: 558 IVDSFNKQILRIE---EQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQRR 614
+V QI ++ E K N E+++R+ + + + L ++ E R
Sbjct: 1112 VVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQEL-RT 1170
Query: 615 RRGETAARLHAALQ 628
+R + A L AL+
Sbjct: 1171 KREQEVAELKKALE 1184
Score = 45.2 bits (102), Expect = 7e-04
Identities = 67/293 (22%), Positives = 124/293 (42%), Gaps = 30/293 (10%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHF-------ESELYKTLDLAHD----- 361
DR + K+ E++N + ++A+KK F ES+L T +L +
Sbjct: 1272 DRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331
Query: 362 --YQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENY-DTVMRLNKQLTDC 418
+ +QL+ EK SL+EQ E + N +K++ L+ DT +++ L
Sbjct: 1332 LNLSSRIRQLEEEKNSLQEQQEEEEE----ARKNLEKQVLALQSQLADTKKKVDDDL-GT 1386
Query: 419 VKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVI 478
+++LEEA +K ++ + E + L QE D L ++ +R +
Sbjct: 1387 IESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQ----V 1442
Query: 479 EQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELK---CHYQKQLEDAVLAKLQE 535
L +KQ + ++L + + R E + E + + LE+A+ AK +E
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK-EE 1501
Query: 536 FQEQLDRAEREMENDARLKEN--NIVDSFNKQILRIEEQHKLEINVLEEKQRE 586
F+ Q + +ME+ K++ V K +E+Q + LEE + E
Sbjct: 1502 FERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDE 1554
Score = 44.8 bits (101), Expect = 0.001
Identities = 61/314 (19%), Positives = 141/314 (44%), Gaps = 23/314 (7%)
Query: 314 DRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEK 373
D + ++ L K + E+E + D+ +++ S+ +DL +D Q++
Sbjct: 1584 DEQNEEKKRLLIKQVRELE--AELEDERKQRALAVASKKKMEIDL----KDLEAQIEAAN 1637
Query: 374 KSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLE-EALEKEKFA 432
K+ +E + +L + + + +E++ + + D + +K+ +K+LE E L+ ++
Sbjct: 1638 KARDEVIK-QLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEEL 1696
Query: 433 HDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEV 492
S ++ +R + ++ T + + LL K E +R A +E++L E+Q+ +
Sbjct: 1697 ASSERARRHAEQERDELADEITNSASGKSALLDEKRRLE-ARIAQLEEELEEEQSNMELL 1755
Query: 493 LKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDAR 552
+ +V TL L +++ Q D +L+ ++L +E+E +
Sbjct: 1756 NDRFRKTTLQVDTLNAELAAERSAA------QKSDNARQQLERQNKELKAKLQELEGAVK 1809
Query: 553 LKENNIVDSFNKQILRIEEQHKLEINVLEEKQREEIKLYRLQLAQAAEKLGLLESKVECQ 612
K + + +I ++EEQ LE++ +E +L + + +KL + +VE +
Sbjct: 1810 SKFKATISALEAKIGQLEEQ-------LEQEAKERAAANKL-VRRTEKKLKEIFMQVEDE 1861
Query: 613 RRRRGETAARLHAA 626
RR + ++ A
Sbjct: 1862 RRHADQYKEQMEKA 1875
Score = 44.4 bits (100), Expect = 0.001
Identities = 85/386 (22%), Positives = 162/386 (41%), Gaps = 35/386 (9%)
Query: 212 ESLKFIQNKYIDTID--SDLLSLSELWGDKAERTTGYNRGDKVDI-IKLEEERLKREHCE 268
ESL+ + K + + S L L DK E+T + + D+ + L+ +R + E
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1447
Query: 269 AMIXXXXXXXXXXXXXXA-VAMKVDRAKDAAISKLREAWLRLTNSLDRA---EDRHRKAL 324
A A + DRA+ A K +A L L +L+ A ++ +
Sbjct: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA-LSLARALEEALEAKEEFERQN 1506
Query: 325 EKMICEVENFRVVADDAQKKTSHFESELYKTLDLAHDYQDKCKQLQNEKKSLEE-QLNTE 383
+++ ++E+ DD K E + + + ++L++E ++ E+ +L E
Sbjct: 1507 KQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE 1566
Query: 384 LDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITEL 443
+ N+ M + ++++ E + RL L V+ LE LE E+
Sbjct: 1567 V-NMQAMKAQFERDLQTRDEQNEEKKRL---LIKQVRELEAELEDER------------- 1609
Query: 444 NKRIQSVNDETLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEV 503
+R +V + + +DL ++R VI+Q L + Q Q + ++ + E
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ-LRKLQAQMKDYQRELE----EA 1664
Query: 504 KTLRQHLELQKNELKCHYQKQLEDAVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFN 563
+ R + Q E + K LE +L +LQE +RA R E + + I +S +
Sbjct: 1665 RASRDEIFAQSKESEKKL-KSLEAEIL-QLQEELASSERARRHAEQERDELADEITNSAS 1722
Query: 564 KQILRIEEQHKLEINV--LEEKQREE 587
+ ++E+ +LE + LEE+ EE
Sbjct: 1723 GKSALLDEKRRLEARIAQLEEELEEE 1748
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/335 (21%), Positives = 145/335 (43%), Gaps = 25/335 (7%)
Query: 301 KLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTSHFESELYKT---LD 357
KL E + +S E+ K L K+ + E ++ KK EL K LD
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLD 1061
Query: 358 -LAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDTVMRLNKQLT 416
D QD+ +LQ + L+ QL + + + L+ D E L +N +++ ++L
Sbjct: 1062 GETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDE--TLHKN--NALKVVRELQ 1117
Query: 417 DCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSKVNEERSRCA 476
+ L+E E EK + + + +L++ +++ L T+ D L + ++ R
Sbjct: 1118 AQIAELQEDFESEKASRNKAEKQKRDLSEELEA------LKTELEDTLDTTAAQQELR-T 1170
Query: 477 VIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLEDA--VLAKLQ 534
EQ++ E + E K + +++ +RQ EL +QLE A A L+
Sbjct: 1171 KREQEVAELKKALEEETKN---HEAQIQDMRQRHATALEEL----SEQLEQAKRFKANLE 1223
Query: 535 EFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLE-EKQREEIKLYRL 593
+ ++ L+ +E+ + ++ + +S +K+ + +L V E ++ R E+
Sbjct: 1224 KNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKAS 1283
Query: 594 QLAQAAEKLGLLESKVECQRRRRGETAARLHAALQ 628
+L + + L + E + + + AA L + LQ
Sbjct: 1284 KLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQ 1318
Score = 43.6 bits (98), Expect = 0.002
Identities = 46/273 (16%), Positives = 119/273 (43%), Gaps = 17/273 (6%)
Query: 287 VAMKVDRAKDAAISKLREAWLRLTNSLDRAEDRHRKALEKMICEVENFRVVADDAQKKTS 346
+ +K A+ A +K R+ ++ L +++ LE+ + + +++KK
Sbjct: 1624 IDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLK 1683
Query: 347 HFESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNK----------DK 396
E+E+ + + + + + E+ L +++ + +L K ++
Sbjct: 1684 SLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEE 1743
Query: 397 EIDVLKENYDTVMRLNKQLTDCVKNLEEALEKEKFA---HDSTKSNITELNKRIQSVNDE 453
E++ + N + + ++ T V L L E+ A D+ + + NK +++ E
Sbjct: 1744 ELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQE 1803
Query: 454 TLLLTQERDLLKSKVNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQ 513
L + K+ ++ ++ +E+QL ++ + + K + ++K + +E +
Sbjct: 1804 --LEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDE 1861
Query: 514 KNELKCHYQKQLEDAVLAKLQEFQEQLDRAERE 546
+ Y++Q+E A A++++ + QL+ AE E
Sbjct: 1862 RRHAD-QYKEQMEKA-NARMKQLKRQLEEAEEE 1892
Score = 37.5 bits (83), Expect = 0.15
Identities = 54/271 (19%), Positives = 109/271 (40%), Gaps = 5/271 (1%)
Query: 348 FESELYKTLDLAHDYQDKCKQLQNEKKSLEEQLNTELDNVNVMLSNKDKEIDVLKENYDT 407
FESE +D ++L+ K LE+ L+T + + + ++ K +
Sbjct: 1127 FESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEE 1186
Query: 408 VMRLNKQLTDCVKNLEEALEKEKFAHDSTKSNITELNKRIQSVNDETLLLTQERDLLKSK 467
Q+ D + ALE+ + K L K Q + + L E +L+
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV 1246
Query: 468 VNEERSRCAVIEQQLCEKQNQCSEVLKKCDFLDNEVKTLRQHLELQKNELKCHYQKQLED 527
E + ++ Q+ E + SE + L + L+ L+ L+ +K ++
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 528 AVLAKLQEFQEQLDRAEREMENDARLKENNIVDSFNKQILRIEEQHKLEINVLEEKQREE 587
A A E Q Q + + E +L ++ + ++ ++EQ + E + +++
Sbjct: 1307 AKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Query: 588 IKLYRLQLAQAAEK----LGLLESKVECQRR 614
+ L + QLA +K LG +ES E +++
Sbjct: 1367 LAL-QSQLADTKKKVDDDLGTIESLEEAKKK 1396
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.126 0.343
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 79,894,153
Number of Sequences: 224733
Number of extensions: 3153502
Number of successful extensions: 24959
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 328
Number of HSP's successfully gapped in prelim test: 1983
Number of HSP's that attempted gapping in prelim test: 16687
Number of HSP's gapped (non-prelim): 7151
length of query: 660
length of database: 73,234,838
effective HSP length: 95
effective length of query: 565
effective length of database: 51,885,203
effective search space: 29315139695
effective search space used: 29315139695
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 68 (31.5 bits)
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