Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002197-TA|BGIBMGA002197-PA|IPR000719|Protein kinase,
IPR001054|Adenylyl cyclase class-3/4/guanylyl cyclase, IPR010916|TonB
box, N-terminal, IPR002290|Serine/threonine protein kinase,
IPR001245|Tyrosine protein kinase, IPR011009|Protein kinase-like
(1244 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L37378-1|AAA74451.1| 1108|Homo sapiens guanylyl cyclase protein. 562 e-159
AL031387-4|CAB41303.1| 1108|Homo sapiens guanylate cyclase 2F, r... 562 e-159
M92432-1|AAA60547.1| 1103|Homo sapiens guanylyl cyclase protein. 557 e-157
AJ222657-1|CAA10914.1| 1103|Homo sapiens guanylyl cyclase protein. 557 e-157
AB005647-1|BAA81737.1| 1047|Homo sapiens atrial natriuretic pept... 471 e-132
BC023017-1|AAH23017.1| 618|Homo sapiens NPR2 protein protein. 470 e-131
AL133410-13|CAI10987.1| 1047|Homo sapiens natriuretic peptide re... 470 e-131
X15357-1|CAA33417.1| 1061|Homo sapiens ANP-A receptor preprotein... 468 e-131
BC063304-1|AAH63304.1| 1061|Homo sapiens natriuretic peptide rec... 468 e-131
AL713889-4|CAI13613.1| 1061|Homo sapiens natriuretic peptide rec... 468 e-131
AF190631-1|AAF01340.1| 1061|Homo sapiens natriuretic peptide rec... 468 e-131
AB010491-1|BAA31199.1| 1061|Homo sapiens natriuretic peptide A t... 468 e-131
S72628-1|AAD14112.1| 415|Homo sapiens atrial natriuretic peptid... 413 e-114
S57551-1|AAB19934.2| 1073|Homo sapiens guanylate cyclase-coupled... 368 e-101
M73489-1|AAA36655.1| 1073|Homo sapiens heat-stable enterotoxin r... 368 e-101
AJ005282-1|CAA06466.1| 995|Homo sapiens NPR-Bi protein. 366 e-100
AL713889-5|CAI13614.1| 255|Homo sapiens natriuretic peptide rec... 278 1e-73
AF038499-1|AAD09440.2| 617|Homo sapiens soluble guanylyl cyclas... 205 7e-52
X63282-1|CAA44921.1| 732|Homo sapiens alpha2-subunit of soluble... 176 5e-43
BC130488-1|AAI30489.1| 732|Homo sapiens guanylate cyclase 1, so... 176 5e-43
BC130484-1|AAI30485.1| 732|Homo sapiens guanylate cyclase 1, so... 176 5e-43
Y15723-1|CAA75738.1| 690|Homo sapiens soluble guanylyl cyclase ... 173 3e-42
U58855-1|AAB94794.1| 690|Homo sapiens soluble guanylate cyclase... 173 3e-42
AF233750-1|AAF64043.1| 564|Homo sapiens soluble guanylate cycla... 173 3e-42
BC028384-1|AAH28384.1| 690|Homo sapiens GUCY1A3 protein protein. 172 6e-42
X66533-1|CAA47144.1| 619|Homo sapiens guanylate cyclase protein. 166 4e-40
BC047620-1|AAH47620.2| 619|Homo sapiens guanylate cyclase 1, so... 166 4e-40
X66534-1|CAA47145.1| 717|Homo sapiens guanylate cyclase protein. 161 2e-38
Z50053-1|CAA90393.1| 763|Homo sapiens alpha2i-subunit of solubl... 156 5e-37
AF020340-1|AAB94877.1| 586|Homo sapiens soluble guanylate cycla... 136 5e-31
BC064923-1|AAH64923.1| 1168|Homo sapiens ADCY6 protein protein. 126 5e-28
AF497517-1|AAM94374.1| 894|Homo sapiens adenylate cyclase type ... 126 5e-28
AF250226-1|AAF82478.1| 1168|Homo sapiens adenylyl cyclase type V... 126 5e-28
AB007882-1|BAA24852.2| 1160|Homo sapiens KIAA0422 protein. 126 5e-28
AL160157-1|CAI15432.2| 385|Homo sapiens guanylate cyclase 1, so... 116 7e-25
DQ008441-1|AAY27880.1| 1353|Homo sapiens adenylyl cyclase type 9... 115 1e-24
DQ005545-1|AAY21237.1| 1353|Homo sapiens adenylyl cyclase type 9... 115 1e-24
AY028959-1|AAK29464.1| 1353|Homo sapiens adenylate cyclase type ... 115 1e-24
AF036927-1|AAC24201.1| 1294|Homo sapiens adenylyl cyclase type I... 115 1e-24
AB011092-1|BAA25446.3| 1364|Homo sapiens KIAA0520 protein protein. 115 1e-24
AB209496-1|BAD92733.1| 1045|Homo sapiens brain adenylate cyclase... 113 5e-24
AJ133123-1|CAB65084.1| 1353|Homo sapiens adenylyl cyclase type I... 111 1e-23
L05500-1|AAA02907.1| 839|Homo sapiens adenylyl cyclase protein. 110 3e-23
BC117475-1|AAI17476.1| 1077|Homo sapiens adenylate cyclase 4 pro... 107 2e-22
BC117473-1|AAI17474.1| 1077|Homo sapiens adenylate cyclase 4 pro... 107 2e-22
AK056745-1|BAB71270.1| 506|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AF497516-1|AAM94373.1| 1077|Homo sapiens adenylate cyclase type ... 107 2e-22
BC126235-1|AAI26236.1| 1144|Homo sapiens adenylate cyclase 3 pro... 105 1e-21
AF033861-1|AAD13403.1| 1144|Homo sapiens type III adenylyl cycla... 105 1e-21
AC012073-2|AAY14787.1| 1144|Homo sapiens unknown protein. 105 1e-21
AB011083-1|BAA25437.1| 933|Homo sapiens KIAA0511 protein protein. 105 1e-21
DQ104739-1|AAZ13596.1| 1120|Homo sapiens brain adenylate cyclase... 104 2e-21
X74210-1|CAA52282.1| 476|Homo sapiens adenylate cyclase protein. 102 7e-21
L21993-1|AAA64923.1| 476|Homo sapiens adenylyl cyclase protein. 102 7e-21
BC111743-1|AAI11744.1| 1091|Homo sapiens adenylate cyclase 2 (br... 102 7e-21
AF410885-1|AAP97285.1| 1091|Homo sapiens adenylyl cyclase type I... 102 7e-21
AF070583-1|AAC28647.1| 367|Homo sapiens adenylyl cyclase protein. 102 7e-21
AB028983-1|BAA83012.1| 887|Homo sapiens KIAA1060 protein protein. 102 7e-21
Z35309-1|CAA84552.1| 1251|Homo sapiens adenylyl cyclase protein. 102 9e-21
D25538-1|BAA05021.2| 1088|Homo sapiens KIAA0037 protein. 100 3e-20
BC126271-1|AAI26272.1| 1080|Homo sapiens adenylate cyclase 7 pro... 100 3e-20
M83533-1|AAA35523.2| 675|Homo sapiens adenylyl cyclase type V p... 98 2e-19
AK075424-1|BAC11613.1| 378|Homo sapiens protein ( Homo sapiens ... 97 3e-19
BC039891-1|AAH39891.1| 433|Homo sapiens ADCY7 protein protein. 95 1e-18
BC015982-1|AAH15982.2| 130|Homo sapiens ADCY4 protein protein. 84 3e-15
U50062-1|AAC32232.1| 671|Homo sapiens RIP protein kinase protein. 79 7e-14
BC126256-1|AAI26257.1| 671|Homo sapiens receptor (TNFRSF)-inter... 79 7e-14
BC126254-1|AAI26255.1| 671|Homo sapiens receptor (TNFRSF)-inter... 79 7e-14
AY682848-1|AAT74626.1| 671|Homo sapiens receptor (TNFRSF)-inter... 79 7e-14
AL031963-3|CAD70625.1| 671|Homo sapiens receptor (TNFRSF)-inter... 79 7e-14
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 77 5e-13
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 76 9e-13
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 76 9e-13
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 76 9e-13
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 76 9e-13
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 75 2e-12
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 75 2e-12
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 75 2e-12
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 75 2e-12
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 75 2e-12
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 75 2e-12
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 75 2e-12
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 75 2e-12
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 74 4e-12
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 73 6e-12
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 73 6e-12
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 73 6e-12
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 73 6e-12
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 73 6e-12
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 73 6e-12
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 73 6e-12
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 73 6e-12
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 73 6e-12
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 73 6e-12
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 72 1e-11
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 72 1e-11
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 72 1e-11
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 72 1e-11
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 72 1e-11
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 72 1e-11
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 72 1e-11
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 71 2e-11
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 71 2e-11
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 71 2e-11
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 71 2e-11
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 71 2e-11
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 71 2e-11
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 71 2e-11
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 70 5e-11
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 70 5e-11
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 70 5e-11
AC069008-1|AAS07467.1| 105|Homo sapiens unknown protein. 70 5e-11
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 70 6e-11
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 69 8e-11
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 69 8e-11
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 69 8e-11
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 69 8e-11
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 69 8e-11
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 69 8e-11
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 69 1e-10
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 69 1e-10
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 69 1e-10
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 69 1e-10
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 69 1e-10
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 69 1e-10
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 69 1e-10
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 69 1e-10
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 69 1e-10
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 69 1e-10
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 69 1e-10
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 69 1e-10
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 69 1e-10
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 69 1e-10
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 69 1e-10
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 69 1e-10
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 69 1e-10
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 69 1e-10
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 68 2e-10
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 68 2e-10
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 68 2e-10
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 68 2e-10
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 68 2e-10
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 68 2e-10
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 68 2e-10
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 68 2e-10
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 68 2e-10
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 68 2e-10
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 68 2e-10
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 68 2e-10
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 68 2e-10
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 67 4e-10
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 67 4e-10
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 67 4e-10
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 67 4e-10
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 67 4e-10
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 67 4e-10
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 66 6e-10
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 66 6e-10
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 66 6e-10
BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ra... 66 6e-10
BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein. 66 6e-10
BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein. 66 6e-10
AY345972-1|AAQ24226.1| 829|Homo sapiens kinase suppressor of Ra... 66 6e-10
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 66 6e-10
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 66 6e-10
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 66 6e-10
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 66 6e-10
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 66 6e-10
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 66 6e-10
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 66 6e-10
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 66 6e-10
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 66 6e-10
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 66 6e-10
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 66 6e-10
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 66 7e-10
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 66 7e-10
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 66 7e-10
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 66 7e-10
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 66 7e-10
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 66 7e-10
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 66 7e-10
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 66 1e-09
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 66 1e-09
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 66 1e-09
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 66 1e-09
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-09
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-09
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 66 1e-09
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 66 1e-09
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-09
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 66 1e-09
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-09
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 66 1e-09
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 66 1e-09
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 66 1e-09
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 66 1e-09
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 66 1e-09
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 66 1e-09
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 65 1e-09
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 65 1e-09
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 65 1e-09
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 65 2e-09
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 65 2e-09
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 65 2e-09
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 65 2e-09
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 65 2e-09
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 65 2e-09
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 64 2e-09
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 64 2e-09
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 64 2e-09
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 64 2e-09
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 64 2e-09
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 64 2e-09
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 64 2e-09
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 64 2e-09
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 64 2e-09
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 64 2e-09
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 64 3e-09
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 64 3e-09
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 64 3e-09
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 64 3e-09
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 64 3e-09
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 64 3e-09
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 64 3e-09
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 64 3e-09
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 64 3e-09
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 64 3e-09
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 64 3e-09
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 64 3e-09
AB231718-1|BAE46879.1| 54|Homo sapiens hypothetical protein pr... 64 3e-09
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 64 3e-09
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 64 3e-09
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 64 4e-09
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 64 4e-09
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 64 4e-09
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 64 4e-09
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 64 4e-09
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 64 4e-09
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 64 4e-09
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 63 5e-09
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 63 5e-09
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 63 5e-09
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 63 5e-09
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 63 5e-09
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 63 5e-09
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 63 5e-09
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 63 5e-09
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 63 5e-09
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 63 5e-09
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 63 5e-09
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 63 5e-09
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 63 5e-09
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 63 5e-09
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 63 5e-09
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 63 5e-09
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 63 5e-09
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 63 5e-09
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 63 5e-09
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 63 5e-09
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 63 5e-09
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 63 5e-09
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 63 5e-09
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 63 5e-09
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 63 7e-09
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 63 7e-09
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 63 7e-09
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 63 7e-09
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 63 7e-09
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 63 7e-09
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 63 7e-09
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 62 9e-09
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 62 9e-09
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 62 9e-09
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 62 9e-09
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 62 9e-09
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 62 9e-09
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 62 9e-09
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 62 9e-09
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 62 9e-09
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 62 9e-09
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 62 9e-09
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 62 9e-09
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 62 1e-08
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 62 1e-08
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 62 1e-08
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 62 1e-08
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 62 1e-08
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 62 1e-08
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 62 1e-08
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 62 1e-08
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 62 1e-08
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 62 1e-08
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 62 1e-08
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 62 1e-08
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 62 1e-08
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 62 1e-08
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 62 1e-08
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 62 1e-08
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 62 1e-08
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 62 1e-08
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 62 2e-08
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 62 2e-08
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 62 2e-08
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 62 2e-08
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 62 2e-08
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 62 2e-08
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 62 2e-08
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 62 2e-08
BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting se... 62 2e-08
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 62 2e-08
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 62 2e-08
AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting pr... 62 2e-08
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 62 2e-08
AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens ... 62 2e-08
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 62 2e-08
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 62 2e-08
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 62 2e-08
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 62 2e-08
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 61 2e-08
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 61 2e-08
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 61 2e-08
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 61 2e-08
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 61 2e-08
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 61 2e-08
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 61 2e-08
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 61 2e-08
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 61 2e-08
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 61 2e-08
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 61 2e-08
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 61 2e-08
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 61 2e-08
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 61 2e-08
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 61 2e-08
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 61 2e-08
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 61 2e-08
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 61 2e-08
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 61 2e-08
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 61 2e-08
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 61 2e-08
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 61 2e-08
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 61 3e-08
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 61 3e-08
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 61 3e-08
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 61 3e-08
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 61 3e-08
AL451136-2|CAI13093.1| 571|Homo sapiens testis-specific kinase ... 61 3e-08
AL359540-12|CAI21724.1| 571|Homo sapiens testis-specific kinase... 61 3e-08
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 61 3e-08
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 61 3e-08
AB057597-1|BAB62909.1| 571|Homo sapiens testicular protein kina... 61 3e-08
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 60 4e-08
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 60 4e-08
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 60 4e-08
AF156884-1|AAD39005.1| 518|Homo sapiens RIP-like kinase protein. 60 4e-08
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 60 5e-08
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 60 5e-08
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 60 5e-08
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 60 5e-08
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 60 5e-08
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 60 5e-08
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 60 5e-08
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 60 5e-08
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 60 5e-08
BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein. 60 5e-08
AL451136-3|CAI13092.1| 542|Homo sapiens testis-specific kinase ... 60 5e-08
AL359540-13|CAI21723.1| 542|Homo sapiens testis-specific kinase... 60 5e-08
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 60 5e-08
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 60 5e-08
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 60 5e-08
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 60 6e-08
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 60 6e-08
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 60 6e-08
BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a prote... 60 6e-08
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 60 6e-08
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 60 6e-08
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 60 6e-08
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 60 6e-08
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 60 6e-08
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 60 6e-08
AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant ... 60 6e-08
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 59 9e-08
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 59 9e-08
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 59 9e-08
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 59 9e-08
U38894-1|AAC50714.1| 388|Homo sapiens tyrosine kinase t-Ror1 pr... 59 1e-07
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 59 1e-07
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 59 1e-07
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 59 1e-07
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 59 1e-07
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 59 1e-07
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 59 1e-07
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 59 1e-07
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 59 1e-07
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 59 1e-07
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 59 1e-07
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 59 1e-07
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 59 1e-07
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 59 1e-07
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 59 1e-07
X06369-1|CAA29667.1| 142|Homo sapiens lck tyrosine kinase (AA 1... 58 1e-07
X04476-1|CAA28165.1| 135|Homo sapiens protein ( Human mRNA frag... 58 1e-07
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 58 1e-07
U43586-1|AAC50354.1| 635|Homo sapiens KSR1 protein. 58 1e-07
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 58 1e-07
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 58 1e-07
BC004553-1|AAH04553.1| 540|Homo sapiens receptor-interacting se... 58 1e-07
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 58 1e-07
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 58 1e-07
AY358814-1|AAQ89173.1| 540|Homo sapiens RIPK2 protein. 58 1e-07
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 58 1e-07
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 58 1e-07
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 58 1e-07
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 58 1e-07
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 58 1e-07
AF078530-1|AAC27722.1| 540|Homo sapiens receptor interacting pr... 58 1e-07
AF064824-1|AAC25668.1| 540|Homo sapiens CARD-containing ICE ass... 58 1e-07
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 58 1e-07
AF027706-1|AAC34970.1| 540|Homo sapiens serine/threonine kinase... 58 1e-07
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 58 1e-07
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 58 1e-07
AC004003-1|AAC24561.1| 540|Homo sapiens WUGSC:H_RG437L15.1 prot... 58 1e-07
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 58 2e-07
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 58 2e-07
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 58 2e-07
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 58 2e-07
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 58 2e-07
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 58 2e-07
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 58 2e-07
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 58 2e-07
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 58 2e-07
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 58 2e-07
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 58 3e-07
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 58 3e-07
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 58 3e-07
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 58 3e-07
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 58 3e-07
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 58 3e-07
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 58 3e-07
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 58 3e-07
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 57 3e-07
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 57 3e-07
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 57 3e-07
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 57 3e-07
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 57 3e-07
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 57 3e-07
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 57 3e-07
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 57 3e-07
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 57 3e-07
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 57 3e-07
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 57 3e-07
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 57 3e-07
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 57 3e-07
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 57 3e-07
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 57 3e-07
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 57 3e-07
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 57 5e-07
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 57 5e-07
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 57 5e-07
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 57 5e-07
AY524045-1|AAS94254.1| 540|Homo sapiens GIG30 protein. 57 5e-07
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 57 5e-07
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 57 5e-07
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 57 5e-07
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 57 5e-07
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 57 5e-07
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 57 5e-07
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 57 5e-07
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 57 5e-07
L26921-1|AAA60366.1| 80|Homo sapiens guanyl cyclase protein. 56 6e-07
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 56 6e-07
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 56 6e-07
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 56 6e-07
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 56 6e-07
>L37378-1|AAA74451.1| 1108|Homo sapiens guanylyl cyclase protein.
Length = 1108
Score = 562 bits (1387), Expect = e-159
Identities = 276/504 (54%), Positives = 365/504 (72%), Gaps = 9/504 (1%)
Query: 599 YKGDAVHLRHLQVT--GTLE-LKRKSTDVLLLMQNLRQENVNPFIGCLCE-GRPALVFDE 654
Y+GD V L+ + G L+ +K +++DV +M++LR EN+NP +G + G A+V +
Sbjct: 566 YEGDWVWLKKFSLGDFGDLKSIKSRASDVFEMMKDLRHENINPLLGFFYDSGMFAIVTEF 625
Query: 655 CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVL 714
C RGSLED+L D+KLDW F+ SLL DL+KGM+YLH HGRL SRNCVVD R+VL
Sbjct: 626 CSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKYLHHREF-VHGRLKSRNCVVDGRFVL 684
Query: 715 RVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+VTDYG + L + + ELLWTAPEL+R R G L + +GDV+SFAIIMQE
Sbjct: 685 KVTDYGFNDILEMLRLSEEESSMEELLWTAPELLRAPR--GSRLGSFAGDVYSFAIIMQE 742
Query: 775 VIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
V+VRG P+CM+ +EII++L +PPP+ RP V APPE + +M+QCW+EA + RP F
Sbjct: 743 VMVRGTPFCMMDLPAQEIINRLKKPPPVYRPVVPPEHAPPECLQLMKQCWAEAAEQRPTF 802
Query: 835 NRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLP 894
+ + + F+ +G+K NI+DSM MLE+YS+NLE+LIRERTE+L++EK+KTE+LL +MLP
Sbjct: 803 DEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLP 862
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
SVAE L G VEPE F+ V++YFSDIVGFT ++A S ++VVDLLNDLYT FDA I
Sbjct: 863 PSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGS 922
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRD-HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIG 1013
+ VYKVETIGDAYMV GLP+R HA +A M+L +L G F++RH+P+ P+ +RIG
Sbjct: 923 HDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIG 982
Query: 1014 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLL-AAGGYKLR 1072
LH+GP AGVVGLTMPRYCLFGDTVNTASRMESTG +RI +S +T L + GY++
Sbjct: 983 LHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVE 1042
Query: 1073 SRGLTQIKGKGAMHTYWLLGKEGF 1096
RG T++KGKG T+WL+GK+GF
Sbjct: 1043 LRGRTELKGKGTEETFWLIGKKGF 1066
>AL031387-4|CAB41303.1| 1108|Homo sapiens guanylate cyclase 2F,
retinal protein.
Length = 1108
Score = 562 bits (1387), Expect = e-159
Identities = 276/504 (54%), Positives = 365/504 (72%), Gaps = 9/504 (1%)
Query: 599 YKGDAVHLRHLQVT--GTLE-LKRKSTDVLLLMQNLRQENVNPFIGCLCE-GRPALVFDE 654
Y+GD V L+ + G L+ +K +++DV +M++LR EN+NP +G + G A+V +
Sbjct: 566 YEGDWVWLKKFSLGDFGDLKSIKSRASDVFEMMKDLRHENINPLLGFFYDSGMFAIVTEF 625
Query: 655 CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVL 714
C RGSLED+L D+KLDW F+ SLL DL+KGM+YLH HGRL SRNCVVD R+VL
Sbjct: 626 CSRGSLEDILTNQDVKLDWMFKSSLLLDLIKGMKYLHHREF-VHGRLKSRNCVVDGRFVL 684
Query: 715 RVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+VTDYG + L + + ELLWTAPEL+R R G L + +GDV+SFAIIMQE
Sbjct: 685 KVTDYGFNDILEMLRLSEEESSMEELLWTAPELLRAPR--GSRLGSFAGDVYSFAIIMQE 742
Query: 775 VIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
V+VRG P+CM+ +EII++L +PPP+ RP V APPE + +M+QCW+EA + RP F
Sbjct: 743 VMVRGTPFCMMDLPAQEIINRLKKPPPVYRPVVPPEHAPPECLQLMKQCWAEAAEQRPTF 802
Query: 835 NRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLP 894
+ + + F+ +G+K NI+DSM MLE+YS+NLE+LIRERTE+L++EK+KTE+LL +MLP
Sbjct: 803 DEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLP 862
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
SVAE L G VEPE F+ V++YFSDIVGFT ++A S ++VVDLLNDLYT FDA I
Sbjct: 863 PSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGS 922
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRD-HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIG 1013
+ VYKVETIGDAYMV GLP+R HA +A M+L +L G F++RH+P+ P+ +RIG
Sbjct: 923 HDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIG 982
Query: 1014 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLL-AAGGYKLR 1072
LH+GP AGVVGLTMPRYCLFGDTVNTASRMESTG +RI +S +T L + GY++
Sbjct: 983 LHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILQNLSEGYEVE 1042
Query: 1073 SRGLTQIKGKGAMHTYWLLGKEGF 1096
RG T++KGKG T+WL+GK+GF
Sbjct: 1043 LRGRTELKGKGTEETFWLIGKKGF 1066
>M92432-1|AAA60547.1| 1103|Homo sapiens guanylyl cyclase protein.
Length = 1103
Score = 557 bits (1374), Expect = e-157
Identities = 277/513 (53%), Positives = 361/513 (70%), Gaps = 18/513 (3%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-----------CLCEGR 647
Y+GD V L+ + ++ + +Q LR ENV ++G L EG
Sbjct: 555 YEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGN 614
Query: 648 PALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCV 707
A+V + C RGSL+D+L +IKLDW F+ SLL DL+KG+RYLH + AHGRL SRNC+
Sbjct: 615 LAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHRGV-AHGRLKSRNCI 673
Query: 708 VDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIRE-AREGGGWLATQSGDVF 766
VD R+VL++TD+G L Q + P + LWTAPEL+R+ A E G LA GDVF
Sbjct: 674 VDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERRGTLA---GDVF 730
Query: 767 SFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
S AIIMQEV+ R PY ML TPEE++ ++ PPPL RP VSM AP E + +M+QCW+E
Sbjct: 731 SLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAE 790
Query: 827 APDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTE 886
P+LRP + D+F+ + +GRK NI+DSM MLE+YS+NLE+LIRERTE+L++EK+KT+
Sbjct: 791 QPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTD 850
Query: 887 QLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYT 946
+LL +MLP SVAE L G+ VEPE FE+V++YFSDIVGFT ++A S ++VVDLLNDLYT
Sbjct: 851 RLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYT 910
Query: 947 TFDAAIEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPD 1005
FDA I + VYKVETIGDAYMV GLPQR + HA +A M+L +L G FR+RH+P+
Sbjct: 911 LFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPE 970
Query: 1006 TPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLA 1065
P+ +RIGLH+GPC AGVVGLTMPRYCLFGDTVNTASRMESTG +RI ++ +T L A
Sbjct: 971 VPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRA 1030
Query: 1066 A-GGYKLRSRGLTQIKGKGAMHTYWLLGKEGFD 1097
GY++ RG T++KGKGA T+WL+G+ GF+
Sbjct: 1031 LDSGYQVELRGRTELKGKGAEDTFWLVGRRGFN 1063
>AJ222657-1|CAA10914.1| 1103|Homo sapiens guanylyl cyclase protein.
Length = 1103
Score = 557 bits (1374), Expect = e-157
Identities = 277/513 (53%), Positives = 361/513 (70%), Gaps = 18/513 (3%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-----------CLCEGR 647
Y+GD V L+ + ++ + +Q LR ENV ++G L EG
Sbjct: 555 YEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGN 614
Query: 648 PALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCV 707
A+V + C RGSL+D+L +IKLDW F+ SLL DL+KG+RYLH + AHGRL SRNC+
Sbjct: 615 LAVVSEHCTRGSLQDLLAQREIKLDWMFKSSLLLDLIKGIRYLHHRGV-AHGRLKSRNCI 673
Query: 708 VDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIRE-AREGGGWLATQSGDVF 766
VD R+VL++TD+G L Q + P + LWTAPEL+R+ A E G LA GDVF
Sbjct: 674 VDGRFVLKITDHGHGRLLEAQKVLPEPPRAEDQLWTAPELLRDPALERRGTLA---GDVF 730
Query: 767 SFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
S AIIMQEV+ R PY ML TPEE++ ++ PPPL RP VSM AP E + +M+QCW+E
Sbjct: 731 SLAIIMQEVVCRSAPYAMLELTPEEVVQRVRSPPPLCRPLVSMDQAPVECILLMKQCWAE 790
Query: 827 APDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTE 886
P+LRP + D+F+ + +GRK NI+DSM MLE+YS+NLE+LIRERTE+L++EK+KT+
Sbjct: 791 QPELRPSMDHTFDLFKNINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELELEKQKTD 850
Query: 887 QLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYT 946
+LL +MLP SVAE L G+ VEPE FE+V++YFSDIVGFT ++A S ++VVDLLNDLYT
Sbjct: 851 RLLTQMLPPSVAEALKTGTPVEPEYFEQVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYT 910
Query: 947 TFDAAIEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPD 1005
FDA I + VYKVETIGDAYMV GLPQR + HA +A M+L +L G FR+RH+P+
Sbjct: 911 LFDAIIGSHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGTFRMRHMPE 970
Query: 1006 TPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLA 1065
P+ +RIGLH+GPC AGVVGLTMPRYCLFGDTVNTASRMESTG +RI ++ +T L A
Sbjct: 971 VPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNLSTVGILRA 1030
Query: 1066 A-GGYKLRSRGLTQIKGKGAMHTYWLLGKEGFD 1097
GY++ RG T++KGKGA T+WL+G+ GF+
Sbjct: 1031 LDSGYQVELRGRTELKGKGAEDTFWLVGRRGFN 1063
>AB005647-1|BAA81737.1| 1047|Homo sapiens atrial natriuretic peptide
Btype receptor protein.
Length = 1047
Score = 471 bits (1161), Expect = e-132
Identities = 247/503 (49%), Positives = 329/503 (65%), Gaps = 14/503 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDECWR 657
+KG+ V ++H+ +EL R+ L M++++ ++ FIG C+ +V + C R
Sbjct: 543 FKGNVVAIKHVNKK-RIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPR 601
Query: 658 GSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
GSL+D+L D I LDW FR SL++DLVKGM +LH S + +HG L S NCVVDSR+VL++T
Sbjct: 602 GSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKIT 661
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLAT---QSGDVFSFAIIMQE 774
DYGL + T + + LWTAPEL+ G L T Q DV+SF II+QE
Sbjct: 662 DYGLASFRSTAEPDDSHALYAKKLWTAPELL-----SGNPLPTTGMQKADVYSFGIILQE 716
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCRPP-PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R P+ + L +P+EI+ K+ P RPS+ E V +M +CW++ P R
Sbjct: 717 IALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRSQLNEELVLLMERCWAQDPAER 776
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
PDF ++ R+ + +I+D++ +E+Y+NNLE+L+ ERT+ EK+K E LL +
Sbjct: 777 PDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQ 836
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 837 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAI 896
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R + HA +A MAL LL FR+RH P L L
Sbjct: 897 IDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRL 956
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SSTT + L G ++
Sbjct: 957 RIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQ 1016
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGK 1093
L RG ++KGKG M TYWLLG+
Sbjct: 1017 LELRGDVEMKGKGKMRTYWLLGE 1039
>BC023017-1|AAH23017.1| 618|Homo sapiens NPR2 protein protein.
Length = 618
Score = 470 bits (1159), Expect = e-131
Identities = 247/503 (49%), Positives = 329/503 (65%), Gaps = 14/503 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDECWR 657
+KG+ V ++H+ +EL R+ L M++++ ++ FIG C+ +V + C R
Sbjct: 114 FKGNVVAIKHVNKK-RIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPR 172
Query: 658 GSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
GSL+D+L D I LDW FR SL++DLVKGM +LH S + +HG L S NCVVDSR+VL++T
Sbjct: 173 GSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKIT 232
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLAT---QSGDVFSFAIIMQE 774
DYGL + T + + LWTAPEL+ G L T Q DV+SF II+QE
Sbjct: 233 DYGLASFRSTAEPDDSHALYAKKLWTAPELL-----SGNPLPTTGMQKADVYSFGIILQE 287
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCRPP-PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R P+ + L +P+EI+ K+ P RPS+ E V +M +CW++ P R
Sbjct: 288 IALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAER 347
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
PDF ++ R+ + +I+D++ +E+Y+NNLE+L+ ERT+ EK+K E LL +
Sbjct: 348 PDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQ 407
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 408 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAI 467
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R + HA +A MAL LL FR+RH P L L
Sbjct: 468 IDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRL 527
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SSTT + L G ++
Sbjct: 528 RIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQ 587
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGK 1093
L RG ++KGKG M TYWLLG+
Sbjct: 588 LELRGDVEMKGKGKMRTYWLLGE 610
>AL133410-13|CAI10987.1| 1047|Homo sapiens natriuretic peptide
receptor B/guanylate cyclase B (atrionatriuretic peptide
re protein.
Length = 1047
Score = 470 bits (1159), Expect = e-131
Identities = 247/503 (49%), Positives = 329/503 (65%), Gaps = 14/503 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDECWR 657
+KG+ V ++H+ +EL R+ L M++++ ++ FIG C+ +V + C R
Sbjct: 543 FKGNVVAIKHVNKK-RIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPR 601
Query: 658 GSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
GSL+D+L D I LDW FR SL++DLVKGM +LH S + +HG L S NCVVDSR+VL++T
Sbjct: 602 GSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKIT 661
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLAT---QSGDVFSFAIIMQE 774
DYGL + T + + LWTAPEL+ G L T Q DV+SF II+QE
Sbjct: 662 DYGLASFRSTAEPDDSHALYAKKLWTAPELL-----SGNPLPTTGMQKADVYSFGIILQE 716
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCRPP-PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R P+ + L +P+EI+ K+ P RPS+ E V +M +CW++ P R
Sbjct: 717 IALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAER 776
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
PDF ++ R+ + +I+D++ +E+Y+NNLE+L+ ERT+ EK+K E LL +
Sbjct: 777 PDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQ 836
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 837 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAI 896
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R + HA +A MAL LL FR+RH P L L
Sbjct: 897 IDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRL 956
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SSTT + L G ++
Sbjct: 957 RIGVHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGQALKIHVSSTTKDALDELGCFQ 1016
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGK 1093
L RG ++KGKG M TYWLLG+
Sbjct: 1017 LELRGDVEMKGKGKMRTYWLLGE 1039
>X15357-1|CAA33417.1| 1061|Homo sapiens ANP-A receptor preprotein (AA
-32 to 1029) protein.
Length = 1061
Score = 468 bits (1154), Expect = e-131
Identities = 250/505 (49%), Positives = 333/505 (65%), Gaps = 15/505 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRP--ALVFDECW 656
YKG+ V ++ + +EL RK L M++++ E++ F+G C P ++ + C
Sbjct: 559 YKGNLVAVKRVN-RKRIELTRKVLFELKHMRDVQNEHLTRFVGA-CTDPPNICILTEYCP 616
Query: 657 RGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
RGSL+D+L + I LDW FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++
Sbjct: 617 RGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKI 676
Query: 717 TDYGLPALHRTQGLPPAQ--RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
TDYGL + + L P Q + LWTAPEL+R A +Q+GDV+SF II+QE
Sbjct: 677 TDYGLESF---RDLDPEQGHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQE 731
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R + + L +P+EII+++ R P RPS+++ + E +M++CW+E P R
Sbjct: 732 IALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQER 791
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
P F ++ R+ R NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL +
Sbjct: 792 PPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQ 851
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 852 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAV 911
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R R HA VA MAL LL FR+RH P L L
Sbjct: 912 IDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRL 971
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SS T L GG++
Sbjct: 972 RIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFE 1031
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGKEG 1095
L RG ++KGKG + TYWLLG+ G
Sbjct: 1032 LELRGDVEMKGKGKVRTYWLLGERG 1056
>BC063304-1|AAH63304.1| 1061|Homo sapiens natriuretic peptide receptor
A/guanylate cyclase A (atrionatriuretic peptide re
protein.
Length = 1061
Score = 468 bits (1154), Expect = e-131
Identities = 250/505 (49%), Positives = 333/505 (65%), Gaps = 15/505 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRP--ALVFDECW 656
YKG+ V ++ + +EL RK L M++++ E++ F+G C P ++ + C
Sbjct: 559 YKGNLVAVKRVN-RKRIELTRKVLFELKHMRDVQNEHLTRFVGA-CTDPPNICILTEYCP 616
Query: 657 RGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
RGSL+D+L + I LDW FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++
Sbjct: 617 RGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKI 676
Query: 717 TDYGLPALHRTQGLPPAQ--RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
TDYGL + + L P Q + LWTAPEL+R A +Q+GDV+SF II+QE
Sbjct: 677 TDYGLESF---RDLDPEQGHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQE 731
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R + + L +P+EII+++ R P RPS+++ + E +M++CW+E P R
Sbjct: 732 IALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQER 791
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
P F ++ R+ R NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL +
Sbjct: 792 PPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQ 851
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 852 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAV 911
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R R HA VA MAL LL FR+RH P L L
Sbjct: 912 IDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRL 971
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SS T L GG++
Sbjct: 972 RIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFE 1031
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGKEG 1095
L RG ++KGKG + TYWLLG+ G
Sbjct: 1032 LELRGDVEMKGKGKVRTYWLLGERG 1056
>AL713889-4|CAI13613.1| 1061|Homo sapiens natriuretic peptide receptor
A/guanylate cyclase A (atrionatriuretic peptide re
protein.
Length = 1061
Score = 468 bits (1154), Expect = e-131
Identities = 250/505 (49%), Positives = 333/505 (65%), Gaps = 15/505 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRP--ALVFDECW 656
YKG+ V ++ + +EL RK L M++++ E++ F+G C P ++ + C
Sbjct: 559 YKGNLVAVKRVN-RKRIELTRKVLFELKHMRDVQNEHLTRFVGA-CTDPPNICILTEYCP 616
Query: 657 RGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
RGSL+D+L + I LDW FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++
Sbjct: 617 RGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKI 676
Query: 717 TDYGLPALHRTQGLPPAQ--RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
TDYGL + + L P Q + LWTAPEL+R A +Q+GDV+SF II+QE
Sbjct: 677 TDYGLESF---RDLDPEQGHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQE 731
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R + + L +P+EII+++ R P RPS+++ + E +M++CW+E P R
Sbjct: 732 IALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQER 791
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
P F ++ R+ R NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL +
Sbjct: 792 PPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQ 851
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 852 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAV 911
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R R HA VA MAL LL FR+RH P L L
Sbjct: 912 IDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRL 971
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SS T L GG++
Sbjct: 972 RIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFE 1031
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGKEG 1095
L RG ++KGKG + TYWLLG+ G
Sbjct: 1032 LELRGDVEMKGKGKVRTYWLLGERG 1056
>AF190631-1|AAF01340.1| 1061|Homo sapiens natriuretic peptide receptor
A protein.
Length = 1061
Score = 468 bits (1154), Expect = e-131
Identities = 250/505 (49%), Positives = 333/505 (65%), Gaps = 15/505 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRP--ALVFDECW 656
YKG+ V ++ + +EL RK L M++++ E++ F+G C P ++ + C
Sbjct: 559 YKGNLVAVKRVN-RKRIELTRKVLFELKHMRDVQNEHLTRFVGA-CTDPPNICILTEYCP 616
Query: 657 RGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
RGSL+D+L + I LDW FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++
Sbjct: 617 RGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKI 676
Query: 717 TDYGLPALHRTQGLPPAQ--RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
TDYGL + + L P Q + LWTAPEL+R A +Q+GDV+SF II+QE
Sbjct: 677 TDYGLESF---RDLDPEQGHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQE 731
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R + + L +P+EII+++ R P RPS+++ + E +M++CW+E P R
Sbjct: 732 IALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQER 791
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
P F ++ R+ R NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL +
Sbjct: 792 PPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQ 851
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 852 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAV 911
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R R HA VA MAL LL FR+RH P L L
Sbjct: 912 IDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRL 971
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SS T L GG++
Sbjct: 972 RIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFE 1031
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGKEG 1095
L RG ++KGKG + TYWLLG+ G
Sbjct: 1032 LELRGDVEMKGKGKVRTYWLLGERG 1056
>AB010491-1|BAA31199.1| 1061|Homo sapiens natriuretic peptide A type
receptor protein.
Length = 1061
Score = 468 bits (1154), Expect = e-131
Identities = 250/505 (49%), Positives = 333/505 (65%), Gaps = 15/505 (2%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRP--ALVFDECW 656
YKG+ V ++ + +EL RK L M++++ E++ F+G C P ++ + C
Sbjct: 559 YKGNLVAVKRVN-RKRIELTRKVLFELKHMRDVQNEHLTRFVGA-CTDPPNICILTEYCP 616
Query: 657 RGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
RGSL+D+L + I LDW FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++
Sbjct: 617 RGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKI 676
Query: 717 TDYGLPALHRTQGLPPAQ--RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
TDYGL + + L P Q + LWTAPEL+R A +Q+GDV+SF II+QE
Sbjct: 677 TDYGLESF---RDLDPEQGHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQE 731
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R + + L +P+EII+++ R P RPS+++ + E +M++CW+E P R
Sbjct: 732 IALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQER 791
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
P F ++ R+ R NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL +
Sbjct: 792 PPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQ 851
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 852 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAV 911
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R R HA VA MAL LL FR+RH P L L
Sbjct: 912 IDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRL 971
Query: 1011 RIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYK 1070
RIG+HTGP CAGVVGL MPRYCLFGDTVNTASRMES G A +I +SS T L GG++
Sbjct: 972 RIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFE 1031
Query: 1071 LRSRGLTQIKGKGAMHTYWLLGKEG 1095
L RG ++KGKG + TYWLLG+ G
Sbjct: 1032 LELRGDVEMKGKGKVRTYWLLGERG 1056
>S72628-1|AAD14112.1| 415|Homo sapiens atrial natriuretic peptide
receptor guanylate protein.
Length = 415
Score = 413 bits (1017), Expect = e-114
Identities = 218/419 (52%), Positives = 282/419 (67%), Gaps = 11/419 (2%)
Query: 675 FRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQ 734
FR SL +D+VKGM +LH + +HG L S NCVVD R+VL++TDYGL + + L P Q
Sbjct: 2 FRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESF---RDLDPEQ 58
Query: 735 --RTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCM--LSFTPE 790
+ LWTAPEL+R A +Q+GDV+SF II+QE+ +R + + L +P+
Sbjct: 59 GHTVYAKKLWTAPELLRMASPPVR--GSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPK 116
Query: 791 EIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRK 849
EII+++ R P RPS+++ + E +M++CW+E P RP F ++ R+ R
Sbjct: 117 EIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENS 176
Query: 850 INIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEP 909
NI+D++ +E+Y+NNLEEL+ ERT+ EK+K E LL ++LP SVAE+L G V+
Sbjct: 177 SNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQA 236
Query: 910 EEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMV 969
E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA I+ + VYKVETIGDAYMV
Sbjct: 237 EAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMV 296
Query: 970 VGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTM 1028
V GLP R R HA VA MAL LL FR+RH P L LRIG+HTGP CAGVVGL M
Sbjct: 297 VSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKM 356
Query: 1029 PRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHT 1087
PRYCLFGDTVNTASRMES G A +I +SS T L GG++L RG ++KGKG + T
Sbjct: 357 PRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRT 415
>S57551-1|AAB19934.2| 1073|Homo sapiens guanylate cyclase-coupled
enterotoxin receptor protein.
Length = 1073
Score = 368 bits (905), Expect = e-101
Identities = 203/459 (44%), Positives = 279/459 (60%), Gaps = 33/459 (7%)
Query: 651 VFDECWRGSLEDVL-----MADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRN 705
V + C RGSL +VL D +DW F++S+L D+ KGM YLH S HGRL S N
Sbjct: 560 VIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTN 619
Query: 706 CVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDV 765
CVVDSR V+++TD+G ++ LPP ++ LWTAPE +R+A +Q GDV
Sbjct: 620 CVVDSRMVVKITDFGCNSI-----LPP-----KKDLWTAPEHLRQAN------ISQKGDV 663
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPE-EIIDKLCRPPPL--IRPSVSMGAAPPEAVSV--- 819
+S+ II QE+I+R E + LS E I ++ + RP + + A + + V
Sbjct: 664 YSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEVYLL 723
Query: 820 MRQCWSEAPDLRPDFNRLHD----VFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERT 875
++ CW E P+ RPDF ++ +F + + +D++ L+ YS NLE L+ ERT
Sbjct: 724 VKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERT 783
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAV 935
+ E+ + ++L +LPR V + L VEPE +EEV+IYFSDIVGFT + ST +
Sbjct: 784 QLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPM 843
Query: 936 QVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD-HAESVATMALHLLHL 994
+VVD+LND+Y +FD ++ + VYKVETIGDAYMV GLP+R + HA +A MAL +L
Sbjct: 844 EVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSF 903
Query: 995 AGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQ 1054
G F + HLP P+ +RIG+H+GPC AGVVG+ MPRYCLFGDTVNTASRMESTG RI
Sbjct: 904 MGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIH 963
Query: 1055 ISSTTAEKLLAAG-GYKLRSRGLTQIKGKGAMHTYWLLG 1092
+S +T L + RG T +KG+G TYWL G
Sbjct: 964 VSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTG 1002
>M73489-1|AAA36655.1| 1073|Homo sapiens heat-stable enterotoxin
receptor protein.
Length = 1073
Score = 368 bits (905), Expect = e-101
Identities = 203/459 (44%), Positives = 279/459 (60%), Gaps = 33/459 (7%)
Query: 651 VFDECWRGSLEDVL-----MADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRN 705
V + C RGSL +VL D +DW F++S+L D+ KGM YLH S HGRL S N
Sbjct: 560 VIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTN 619
Query: 706 CVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDV 765
CVVDSR V+++TD+G ++ LPP ++ LWTAPE +R+A +Q GDV
Sbjct: 620 CVVDSRMVVKITDFGCNSI-----LPP-----KKDLWTAPEHLRQAN------ISQKGDV 663
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPE-EIIDKLCRPPPL--IRPSVSMGAAPPEAVSV--- 819
+S+ II QE+I+R E + LS E I ++ + RP + + A + + V
Sbjct: 664 YSYGIIAQEIILRKETFYTLSCRDRNEKIFRVENSNGMKPFRPDLFLETAEEKELEVYLL 723
Query: 820 MRQCWSEAPDLRPDFNRLHD----VFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERT 875
++ CW E P+ RPDF ++ +F + + +D++ L+ YS NLE L+ ERT
Sbjct: 724 VKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERT 783
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAV 935
+ E+ + ++L +LPR V + L VEPE +EEV+IYFSDIVGFT + ST +
Sbjct: 784 QLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPM 843
Query: 936 QVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD-HAESVATMALHLLHL 994
+VVD+LND+Y +FD ++ + VYKVETIGDAYMV GLP+R + HA +A MAL +L
Sbjct: 844 EVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSF 903
Query: 995 AGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQ 1054
G F + HLP P+ +RIG+H+GPC AGVVG+ MPRYCLFGDTVNTASRMESTG RI
Sbjct: 904 MGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIH 963
Query: 1055 ISSTTAEKLLAAG-GYKLRSRGLTQIKGKGAMHTYWLLG 1092
+S +T L + RG T +KG+G TYWL G
Sbjct: 964 VSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTG 1002
>AJ005282-1|CAA06466.1| 995|Homo sapiens NPR-Bi protein.
Length = 995
Score = 366 bits (900), Expect = e-100
Identities = 197/427 (46%), Positives = 271/427 (63%), Gaps = 14/427 (3%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDECWR 657
+KG+ V ++H+ +EL R+ L M++++ ++ FIG C+ +V + C R
Sbjct: 543 FKGNVVAIKHVNKK-RIELTRQVLFELKHMRDVQFNHLTRFIGACIDPPNICIVTEYCPR 601
Query: 658 GSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
GSL+D+L D I LDW FR SL++DLVKGM +LH S + +HG L S NCVVDSR+VL++T
Sbjct: 602 GSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSNCVVDSRFVLKIT 661
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLAT---QSGDVFSFAIIMQE 774
DYGL + T + + LWTAPEL+ G L T Q DV+SF II+QE
Sbjct: 662 DYGLASFRSTAEPDDSHALYAKKLWTAPELL-----SGNPLPTTGMQKADVYSFGIILQE 716
Query: 775 VIVRGEPYCM--LSFTPEEIIDKLCRPP-PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
+ +R P+ + L +P+EI+ K+ P RPS+ E V +M +CW++ P R
Sbjct: 717 IALRSGPFYLEGLDLSPKEIVQKVRNGQRPYFRPSIDRTQLNEELVLLMERCWAQDPAER 776
Query: 832 PDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNR 891
PDF ++ R+ + +I+D++ +E+Y+NNLE+L+ ERT+ EK+K E LL +
Sbjct: 777 PDFGQIKGFIRRFNKEGGTSILDNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQ 836
Query: 892 MLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAA 951
+LP SVAE+L G V+ E F+ V+IYFSDIVGFTAL+A ST +QVV LLNDLYT FDA
Sbjct: 837 ILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAI 896
Query: 952 IEQYRVYKVETIGDAYMVVGGLPQRT-RDHAESVATMALHLLHLAGRFRVRHLPDTPLHL 1010
I+ + VYKVETIGDAYMVV GLP R + HA +A MAL LL FR+RH P L L
Sbjct: 897 IDNFDVYKVETIGDAYMVVSGLPGRNGQRHAPEIARMALALLDAVSSFRIRHRPHDQLRL 956
Query: 1011 RIGLHTG 1017
RIG+HTG
Sbjct: 957 RIGVHTG 963
>AL713889-5|CAI13614.1| 255|Homo sapiens natriuretic peptide receptor
A/guanylate cyclase A (atrionatriuretic peptide re
protein.
Length = 255
Score = 278 bits (681), Expect = 1e-73
Identities = 143/234 (61%), Positives = 170/234 (72%), Gaps = 4/234 (1%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
+E+Y+NNLEEL+ ERT+ EK+K E LL ++LP SVAE+L G V+ E F+ V+IYF
Sbjct: 1 MEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYF 60
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRT-R 978
SDIVGFTAL+A ST +QVV LLNDLYT FDA I+ + VYKVETIGDAYMVV GLP R R
Sbjct: 61 SDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGR 120
Query: 979 DHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTV 1038
HA VA MAL LL FR+RH P L LRIG+HTGP CAGVVGL MPRYCLFGDTV
Sbjct: 121 LHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTV 180
Query: 1039 NTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKG---AMHTYW 1089
NTASRMES G A +I +SS T L GG++L RG ++K +G A+ T+W
Sbjct: 181 NTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKVEGEASALPTFW 234
>AF038499-1|AAD09440.2| 617|Homo sapiens soluble guanylyl cyclase
subunit beta 2 protein.
Length = 617
Score = 205 bits (501), Expect = 7e-52
Identities = 109/231 (47%), Positives = 149/231 (64%), Gaps = 5/231 (2%)
Query: 864 SNNLE---ELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFS 920
SN LE E ++ ++ L +EKKKTE LL MLP+ VA +L G +V EF+ +I FS
Sbjct: 336 SNQLERKKEELQVLSKHLAIEKKKTETLLYAMLPKHVANQLREGKKVAAGEFKSCTILFS 395
Query: 921 DIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDH 980
D+V FT + +Q+V++LN +Y+ FD + VYKVETIGDAYMVVGG+P +H
Sbjct: 396 DVVTFTNICTACEPIQIVNVLNSMYSKFDRLTSVHAVYKVETIGDAYMVVGGVPVPIGNH 455
Query: 981 AESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNT 1040
A+ VA AL + ++ + + P+ LR+G+HTGP A VVG MPRYCLFGDTVNT
Sbjct: 456 AQRVANFALG-MRISAKEVTNPVTGEPIQLRVGIHTGPVLADVVGDKMPRYCLFGDTVNT 514
Query: 1041 ASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLL 1091
ASRMES G ++ + S TA + L G+K+ RG ++KGKG M TY+L+
Sbjct: 515 ASRMESHGLPNKVHL-SPTAYRALKNQGFKIIERGEIEVKGKGRMTTYFLI 564
>X63282-1|CAA44921.1| 732|Homo sapiens alpha2-subunit of soluble
guanylyl cyclase protein.
Length = 732
Score = 176 bits (428), Expect = 5e-43
Identities = 99/230 (43%), Positives = 141/230 (61%), Gaps = 11/230 (4%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQ-LDMEKKKTEQLLNRMLP 894
+HD R + G + D + + ++K LE RT Q L+ EKKKT LL + P
Sbjct: 445 IHDATRDVILVGEQAKAQDGLKKRMDKLKATLE-----RTHQALEEEKKKTVDLLYSIFP 499
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
VA++L G +V+ +F++V++ FSDIVGFTA+ A+ T +QV+ +LN+LYT FD
Sbjct: 500 GDVAQQLWQGQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGF 559
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPD-TPLHLRIG 1013
+YKVETIGDAY V GL +++ HA+ +A MAL ++ L+ PD P+ +RIG
Sbjct: 560 LDIYKVETIGDAYCVAAGLHRKSLCHAKPIALMALKMMELSEEVLT---PDGRPIQMRIG 616
Query: 1014 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
+H+G AGVVG+ MPRYCLFG+ V AS+ ES RI +S TT + L
Sbjct: 617 IHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLL 666
>BC130488-1|AAI30489.1| 732|Homo sapiens guanylate cyclase 1,
soluble, alpha 2 protein.
Length = 732
Score = 176 bits (428), Expect = 5e-43
Identities = 99/230 (43%), Positives = 141/230 (61%), Gaps = 11/230 (4%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQ-LDMEKKKTEQLLNRMLP 894
+HD R + G + D + + ++K LE RT Q L+ EKKKT LL + P
Sbjct: 445 IHDATRDVILVGEQAKAQDGLKKRMDKLKATLE-----RTHQALEEEKKKTVDLLYSIFP 499
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
VA++L G +V+ +F++V++ FSDIVGFTA+ A+ T +QV+ +LN+LYT FD
Sbjct: 500 GDVAQQLWQGQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGF 559
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPD-TPLHLRIG 1013
+YKVETIGDAY V GL +++ HA+ +A MAL ++ L+ PD P+ +RIG
Sbjct: 560 LDIYKVETIGDAYCVAAGLHRKSLCHAKPIALMALKMMELSEEVLT---PDGRPIQMRIG 616
Query: 1014 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
+H+G AGVVG+ MPRYCLFG+ V AS+ ES RI +S TT + L
Sbjct: 617 IHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLL 666
>BC130484-1|AAI30485.1| 732|Homo sapiens guanylate cyclase 1,
soluble, alpha 2 protein.
Length = 732
Score = 176 bits (428), Expect = 5e-43
Identities = 99/230 (43%), Positives = 141/230 (61%), Gaps = 11/230 (4%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQ-LDMEKKKTEQLLNRMLP 894
+HD R + G + D + + ++K LE RT Q L+ EKKKT LL + P
Sbjct: 445 IHDATRDVILVGEQAKAQDGLKKRMDKLKATLE-----RTHQALEEEKKKTVDLLYSIFP 499
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
VA++L G +V+ +F++V++ FSDIVGFTA+ A+ T +QV+ +LN+LYT FD
Sbjct: 500 GDVAQQLWQGQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGF 559
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPD-TPLHLRIG 1013
+YKVETIGDAY V GL +++ HA+ +A MAL ++ L+ PD P+ +RIG
Sbjct: 560 LDIYKVETIGDAYCVAAGLHRKSLCHAKPIALMALKMMELSEEVLT---PDGRPIQMRIG 616
Query: 1014 LHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
+H+G AGVVG+ MPRYCLFG+ V AS+ ES RI +S TT + L
Sbjct: 617 IHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLL 666
>Y15723-1|CAA75738.1| 690|Homo sapiens soluble guanylyl cyclase
protein.
Length = 690
Score = 173 bits (422), Expect = 3e-42
Identities = 91/220 (41%), Positives = 131/220 (59%), Gaps = 2/220 (0%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
L+K L+ + + + L+ EKKKT LL + P VA++L G V+ ++F V++ F
Sbjct: 425 LKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLF 484
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD 979
SDIVGFTA+ ++ + +QV+ +LN LYT FD + VYKVETIGDAY V GGL + +
Sbjct: 485 SDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDT 544
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
HA +A MAL ++ L+ H P+ +RIGLH+G AGVVG+ MPRYCLFG+ V
Sbjct: 545 HAVQIALMALKMMELSDEVMSPH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVT 602
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQI 1079
A++ ES +I +S TT L G+ R ++
Sbjct: 603 LANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREEL 642
>U58855-1|AAB94794.1| 690|Homo sapiens soluble guanylate cyclase
large subunit protein.
Length = 690
Score = 173 bits (422), Expect = 3e-42
Identities = 91/220 (41%), Positives = 131/220 (59%), Gaps = 2/220 (0%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
L+K L+ + + + L+ EKKKT LL + P VA++L G V+ ++F V++ F
Sbjct: 425 LKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLF 484
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD 979
SDIVGFTA+ ++ + +QV+ +LN LYT FD + VYKVETIGDAY V GGL + +
Sbjct: 485 SDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDT 544
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
HA +A MAL ++ L+ H P+ +RIGLH+G AGVVG+ MPRYCLFG+ V
Sbjct: 545 HAVQIALMALKMMELSDEVMSPH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVT 602
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQI 1079
A++ ES +I +S TT L G+ R ++
Sbjct: 603 LANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREEL 642
>AF233750-1|AAF64043.1| 564|Homo sapiens soluble guanylate cyclase
large subunit protein.
Length = 564
Score = 173 bits (422), Expect = 3e-42
Identities = 91/220 (41%), Positives = 131/220 (59%), Gaps = 2/220 (0%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
L+K L+ + + + L+ EKKKT LL + P VA++L G V+ ++F V++ F
Sbjct: 299 LKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLF 358
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD 979
SDIVGFTA+ ++ + +QV+ +LN LYT FD + VYKVETIGDAY V GGL + +
Sbjct: 359 SDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDT 418
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
HA +A MAL ++ L+ H P+ +RIGLH+G AGVVG+ MPRYCLFG+ V
Sbjct: 419 HAVQIALMALKMMELSDEVMSPH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVT 476
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQI 1079
A++ ES +I +S TT L G+ R ++
Sbjct: 477 LANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREEL 516
>BC028384-1|AAH28384.1| 690|Homo sapiens GUCY1A3 protein protein.
Length = 690
Score = 172 bits (419), Expect = 6e-42
Identities = 90/220 (40%), Positives = 131/220 (59%), Gaps = 2/220 (0%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
L+K L+ + + + L+ EKKKT LL + P VA++L G V+ ++F V++ F
Sbjct: 425 LKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLF 484
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD 979
SDIVGFTA+ ++ + +QV+ +LN LYT FD + VYKVETIGDAY V GGL + +
Sbjct: 485 SDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDT 544
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
HA +A MA+ ++ L+ H P+ +RIGLH+G AGVVG+ MPRYCLFG+ V
Sbjct: 545 HAVQIALMAVKMMELSDEVMSPH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVT 602
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQI 1079
A++ ES +I +S TT L G+ R ++
Sbjct: 603 LANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREEL 642
>X66533-1|CAA47144.1| 619|Homo sapiens guanylate cyclase protein.
Length = 619
Score = 166 bits (404), Expect = 4e-40
Identities = 102/270 (37%), Positives = 148/270 (54%), Gaps = 19/270 (7%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPR 895
LHD R + G + + + LE ++ L+ +R L+ EKKKT+ LL +LP
Sbjct: 345 LHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRA----LEDEKKKTDTLLYSVLPP 400
Query: 896 SVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST----AVQVVDLLNDLYTTFDAA 951
SVA L V + ++ V+I FS IVGF A ++ A+++V+LLNDLYT FD
Sbjct: 401 SVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTL 460
Query: 952 IEQYR---VYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPL 1008
+ + VYKVET+GD YM V GLP+ HA S+ +AL ++ +AG+ +V +
Sbjct: 461 TDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQV---DGESV 517
Query: 1009 HLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGG 1068
+ IG+HTG GV+G MPRYCLFG+TVN SR E+TG +I +S T L++
Sbjct: 518 QITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPEN 577
Query: 1069 ----YKLRSRGLTQIKGKGAMHTYWLLGKE 1094
+ L RG +KGK W L ++
Sbjct: 578 SDPQFHLEHRGPVSMKGKKEPMQVWFLSRK 607
>BC047620-1|AAH47620.2| 619|Homo sapiens guanylate cyclase 1,
soluble, beta 3 protein.
Length = 619
Score = 166 bits (404), Expect = 4e-40
Identities = 102/270 (37%), Positives = 148/270 (54%), Gaps = 19/270 (7%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPR 895
LHD R + G + + + LE ++ L+ +R L+ EKKKT+ LL +LP
Sbjct: 345 LHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRA----LEDEKKKTDTLLYSVLPP 400
Query: 896 SVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST----AVQVVDLLNDLYTTFDAA 951
SVA L V + ++ V+I FS IVGF A ++ A+++V+LLNDLYT FD
Sbjct: 401 SVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTL 460
Query: 952 IEQYR---VYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPL 1008
+ + VYKVET+GD YM V GLP+ HA S+ +AL ++ +AG+ +V +
Sbjct: 461 TDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQV---DGESV 517
Query: 1009 HLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGG 1068
+ IG+HTG GV+G MPRYCLFG+TVN SR E+TG +I +S T L++
Sbjct: 518 QITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPEN 577
Query: 1069 ----YKLRSRGLTQIKGKGAMHTYWLLGKE 1094
+ L RG +KGK W L ++
Sbjct: 578 SDPQFHLEHRGPVSMKGKKEPMQVWFLSRK 607
>X66534-1|CAA47145.1| 717|Homo sapiens guanylate cyclase protein.
Length = 717
Score = 161 bits (390), Expect = 2e-38
Identities = 86/220 (39%), Positives = 128/220 (58%), Gaps = 2/220 (0%)
Query: 860 LEKYSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYF 919
L+K L+ + + + L+ EKKKT LL + P VA++L G V+ ++F V++ F
Sbjct: 422 LKKRLGKLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQGQVVQAKKFSNVTMLF 481
Query: 920 SDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRD 979
SDIVGFTA+ ++ + +QV+ +LN LYT FD + VYKVETI + +GGL + +
Sbjct: 482 SDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIAMPIVWLGGLHKESDT 541
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
HA +A MAL ++ L+ H P+ +RIGLH+G AGVVG+ MPRYCLFG+ V
Sbjct: 542 HAVQIALMALKMMELSDEVMSPH--GEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVT 599
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQI 1079
A++ ES +I +S TT L G+ R ++
Sbjct: 600 LANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREEL 639
>Z50053-1|CAA90393.1| 763|Homo sapiens alpha2i-subunit of soluble
guanylyl cyclase protein.
Length = 763
Score = 156 bits (378), Expect = 5e-37
Identities = 103/258 (39%), Positives = 146/258 (56%), Gaps = 36/258 (13%)
Query: 837 LHDVFRQMQR-GRKINIVDSMFEMLEKYSNNLEELIRERTEQ-LDMEKKKTEQLLNRMLP 894
+HD R + G + D + + ++K LE RT Q L+ EKKKT LL + P
Sbjct: 445 IHDATRDVILVGEQAKAQDGLKKRMDKLKATLE-----RTHQALEEEKKKTVDLLYSIFP 499
Query: 895 RSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQ 954
VA++L G +V+ +F++V++ FSDIVGFTA+ A+ T +QV+ +LN+LYT FD
Sbjct: 500 GDVAQQLWQGQQVQARKFDDVTMLFSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGF 559
Query: 955 YRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLA-------GR---------- 997
+YKVETIGDAY V GL +++ HA+ +A MAL ++ L+ GR
Sbjct: 560 LDIYKVETIGDAYCVAAGLHRKSLCHAKPIALMALKMMELSEEVLTPDGRPIQPQRSELL 619
Query: 998 --FRV-------RHLPDTPL---HLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRME 1045
F V +H +T L +RIG+H+G AGVVG+ MPRYCLFG+ V AS+ E
Sbjct: 620 FSFPVSIQLVPDQHQSETDLGTEKMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFE 679
Query: 1046 STGAAWRIQISSTTAEKL 1063
S RI +S TT + L
Sbjct: 680 SGSHPRRINVSPTTYQLL 697
>AF020340-1|AAB94877.1| 586|Homo sapiens soluble guanylate cyclase
beta-1 subunit protein.
Length = 586
Score = 136 bits (329), Expect = 5e-31
Identities = 85/230 (36%), Positives = 124/230 (53%), Gaps = 23/230 (10%)
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST-- 933
EQ E K T++L + +RL L R +E ++ + IVGF A ++
Sbjct: 357 EQFREEYKLTQEL------EILTDRLQLTLRALEDEKKKTD---TGIVGFNAFCSKHASG 407
Query: 934 --AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRDHAESVATMA 988
A+++V+LLNDLYT FD + + VYKVET+GD YM V GLP+ HA S+ +A
Sbjct: 408 EGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLA 467
Query: 989 LHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTG 1048
L ++ +AG+ +V + + IG+HTG GV+G MPRYCLFG+TVN SR E+TG
Sbjct: 468 LDMMEIAGQVQV---DGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTG 524
Query: 1049 AAWRIQISSTTAEKLLAAGG----YKLRSRGLTQIKGKGAMHTYWLLGKE 1094
+I +S T L++ + L RG +KGK W L ++
Sbjct: 525 EKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRK 574
>BC064923-1|AAH64923.1| 1168|Homo sapiens ADCY6 protein protein.
Length = 1168
Score = 126 bits (304), Expect = 5e-28
Identities = 80/233 (34%), Positives = 127/233 (54%), Gaps = 19/233 (8%)
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEF----EEVSIYFSDIVGFTA---- 927
E+++ + +LL+ +LP+ VA + R E + E V++ F+ I F+
Sbjct: 935 EEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVE 994
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRT-----RD 979
L A + V+ + LLN++ FD I + R + K++TIG YM GL T R
Sbjct: 995 LEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRS 1054
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
H ++A A+ L+ + ++IGL+ GP AGV+G P+Y ++G+TVN
Sbjct: 1055 HITALADYAMRLMEQMKHINEHSFNN--FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVN 1112
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLLG 1092
+SRM+STG RIQ+ +T ++LAA GY+L RG+ ++KGKG M TY+L G
Sbjct: 1113 VSSRMDSTGVPDRIQV-TTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNG 1164
Score = 105 bits (253), Expect = 8e-22
Identities = 61/196 (31%), Positives = 107/196 (54%), Gaps = 12/196 (6%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERL----------MLGSRVEPEEFEEVSIYFSDIVGFTA 927
L E ++ E+LL +LP+ VA + M+ ++ ++ + VSI F+DI GFT+
Sbjct: 331 LQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTS 390
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATM 987
LA++ TA ++V LN+L+ FD + +++ +GD Y V GLP+ DHA M
Sbjct: 391 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM 450
Query: 988 ALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMEST 1047
+ ++ VR + +++R+G+H+G GV+GL ++ ++ + V A+ ME+
Sbjct: 451 GVDMIEAIS--LVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG 508
Query: 1048 GAAWRIQISSTTAEKL 1063
G A RI I+ T + L
Sbjct: 509 GRAGRIHITRATLQYL 524
>AF497517-1|AAM94374.1| 894|Homo sapiens adenylate cyclase type V
protein.
Length = 894
Score = 126 bits (304), Expect = 5e-28
Identities = 82/236 (34%), Positives = 131/236 (55%), Gaps = 19/236 (8%)
Query: 873 ERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEF----EEVSIYFSDIVGFTA- 927
E E+++ + +LL+ +LP+ VA + R E + E V++ F+ I F+
Sbjct: 657 EEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEF 716
Query: 928 ---LAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRD-- 979
L A + V+ + LLN++ FD I + R + K++TIG YM GL T D
Sbjct: 717 YVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKV 776
Query: 980 ---HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGD 1036
H +++A A+ L+ ++ H + ++IGL+ GP AGV+G P+Y ++G+
Sbjct: 777 GKTHIKALADFAMKLMDQM-KYINEHSFNN-FQMKIGLNIGPVVAGVIGARKPQYDIWGN 834
Query: 1037 TVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLLG 1092
TVN ASRM+STG RIQ+ +T ++LAA Y+L RG+ ++KGKG M TY+L G
Sbjct: 835 TVNVASRMDSTGVPDRIQV-TTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNG 889
Score = 106 bits (254), Expect = 6e-22
Identities = 61/193 (31%), Positives = 105/193 (54%), Gaps = 12/193 (6%)
Query: 881 EKKKTEQLLNRMLPRSVAERL----------MLGSRVEPEEFEEVSIYFSDIVGFTALAA 930
E ++ E+LL +LPR VA + M+ ++ ++ + VSI F+DI GFT+LA+
Sbjct: 57 ENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLAS 116
Query: 931 RSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALH 990
+ TA ++V LN+L+ FD + +++ +GD Y V GLP+ DHA M +
Sbjct: 117 QCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMD 176
Query: 991 LLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAA 1050
++ VR + +++R+G+H+G GV+GL ++ ++ + V A+ ME+ G A
Sbjct: 177 MIEAIS--LVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKA 234
Query: 1051 WRIQISSTTAEKL 1063
RI I+ T L
Sbjct: 235 GRIHITKATLNYL 247
>AF250226-1|AAF82478.1| 1168|Homo sapiens adenylyl cyclase type VI
protein.
Length = 1168
Score = 126 bits (304), Expect = 5e-28
Identities = 80/233 (34%), Positives = 127/233 (54%), Gaps = 19/233 (8%)
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEF----EEVSIYFSDIVGFTA---- 927
E+++ + +LL+ +LP+ VA + R E + E V++ F+ I F+
Sbjct: 935 EEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVE 994
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRT-----RD 979
L A + V+ + LLN++ FD I + R + K++TIG YM GL T R
Sbjct: 995 LEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRS 1054
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
H ++A A+ L+ + ++IGL+ GP AGV+G P+Y ++G+TVN
Sbjct: 1055 HITALADYAMRLMEQMKHINEHSFNN--FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVN 1112
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLLG 1092
+SRM+STG RIQ+ +T ++LAA GY+L RG+ ++KGKG M TY+L G
Sbjct: 1113 VSSRMDSTGVPDRIQV-TTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNG 1164
Score = 105 bits (253), Expect = 8e-22
Identities = 61/196 (31%), Positives = 107/196 (54%), Gaps = 12/196 (6%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERL----------MLGSRVEPEEFEEVSIYFSDIVGFTA 927
L E ++ E+LL +LP+ VA + M+ ++ ++ + VSI F+DI GFT+
Sbjct: 331 LQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTS 390
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATM 987
LA++ TA ++V LN+L+ FD + +++ +GD Y V GLP+ DHA M
Sbjct: 391 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM 450
Query: 988 ALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMEST 1047
+ ++ VR + +++R+G+H+G GV+GL ++ ++ + V A+ ME+
Sbjct: 451 GVDMIEAIS--LVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG 508
Query: 1048 GAAWRIQISSTTAEKL 1063
G A RI I+ T + L
Sbjct: 509 GRAGRIHITRATLQYL 524
>AB007882-1|BAA24852.2| 1160|Homo sapiens KIAA0422 protein.
Length = 1160
Score = 126 bits (304), Expect = 5e-28
Identities = 80/233 (34%), Positives = 127/233 (54%), Gaps = 19/233 (8%)
Query: 876 EQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEF----EEVSIYFSDIVGFTA---- 927
E+++ + +LL+ +LP+ VA + R E + E V++ F+ I F+
Sbjct: 927 EEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVE 986
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRT-----RD 979
L A + V+ + LLN++ FD I + R + K++TIG YM GL T R
Sbjct: 987 LEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRS 1046
Query: 980 HAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVN 1039
H ++A A+ L+ + ++IGL+ GP AGV+G P+Y ++G+TVN
Sbjct: 1047 HITALADYAMRLMEQMKHINEHSFNN--FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVN 1104
Query: 1040 TASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLLG 1092
+SRM+STG RIQ+ +T ++LAA GY+L RG+ ++KGKG M TY+L G
Sbjct: 1105 VSSRMDSTGVPDRIQV-TTDLYQVLAAKGYQLECRGVVKVKGKGEMTTYFLNG 1156
Score = 105 bits (253), Expect = 8e-22
Identities = 61/196 (31%), Positives = 107/196 (54%), Gaps = 12/196 (6%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERL----------MLGSRVEPEEFEEVSIYFSDIVGFTA 927
L E ++ E+LL +LP+ VA + M+ ++ ++ + VSI F+DI GFT+
Sbjct: 376 LQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTS 435
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATM 987
LA++ TA ++V LN+L+ FD + +++ +GD Y V GLP+ DHA M
Sbjct: 436 LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM 495
Query: 988 ALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMEST 1047
+ ++ VR + +++R+G+H+G GV+GL ++ ++ + V A+ ME+
Sbjct: 496 GVDMIEAIS--LVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAG 553
Query: 1048 GAAWRIQISSTTAEKL 1063
G A RI I+ T + L
Sbjct: 554 GRAGRIHITRATLQYL 569
>AL160157-1|CAI15432.2| 385|Homo sapiens guanylate cyclase 1,
soluble, beta 2 protein.
Length = 385
Score = 116 bits (278), Expect = 7e-25
Identities = 61/129 (47%), Positives = 83/129 (64%), Gaps = 3/129 (2%)
Query: 864 SNNLE---ELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFS 920
SN LE E ++ ++ L +EKKKTE LL MLP+ VA +L G +V EF+ +I FS
Sbjct: 234 SNQLERKKEELQVLSKHLAIEKKKTETLLYAMLPKHVANQLREGKKVAAGEFKSCTILFS 293
Query: 921 DIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDH 980
D+V FT + +Q+V++LN +Y+ FD + VYKVETIGDAYMVVGG+P +H
Sbjct: 294 DVVTFTNICTACEPIQIVNVLNSMYSKFDRLTSVHAVYKVETIGDAYMVVGGVPVPIGNH 353
Query: 981 AESVATMAL 989
A+ VA AL
Sbjct: 354 AQRVANFAL 362
>DQ008441-1|AAY27880.1| 1353|Homo sapiens adenylyl cyclase type 9
protein.
Length = 1353
Score = 115 bits (276), Expect = 1e-24
Identities = 71/245 (28%), Positives = 128/245 (52%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 300 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 356
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 357 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 416
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 417 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 476
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HTG G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 477 CQE--KKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 534
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 535 TAKYL 539
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1025 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1083
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1084 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1143
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1144 EMMRVVDDFNNNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1203 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1240
>DQ005545-1|AAY21237.1| 1353|Homo sapiens adenylyl cyclase type 9
protein.
Length = 1353
Score = 115 bits (276), Expect = 1e-24
Identities = 71/245 (28%), Positives = 128/245 (52%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 300 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 356
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 357 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 416
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 417 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 476
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HTG G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 477 CQE--KKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 534
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 535 TAKYL 539
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1025 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1083
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1084 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1143
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1144 EMMRVVDDFNNNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1203 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1240
>AY028959-1|AAK29464.1| 1353|Homo sapiens adenylate cyclase type 9
protein.
Length = 1353
Score = 115 bits (276), Expect = 1e-24
Identities = 71/245 (28%), Positives = 128/245 (52%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 300 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 356
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 357 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 416
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 417 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 476
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HTG G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 477 CQE--KKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 534
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 535 TAKYL 539
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1025 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1083
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1084 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1143
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1144 EMMRVVDDFNNNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1203 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1240
>AF036927-1|AAC24201.1| 1294|Homo sapiens adenylyl cyclase type IX
protein.
Length = 1294
Score = 115 bits (276), Expect = 1e-24
Identities = 71/245 (28%), Positives = 128/245 (52%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 300 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 356
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 357 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 416
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 417 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 476
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HTG G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 477 CQE--KKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 534
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 535 TAKYL 539
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1025 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1083
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1084 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1143
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1144 EMMRVVDDFNNNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1203 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1240
>AB011092-1|BAA25446.3| 1364|Homo sapiens KIAA0520 protein protein.
Length = 1364
Score = 115 bits (276), Expect = 1e-24
Identities = 71/245 (28%), Positives = 128/245 (52%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 311 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 367
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 368 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 427
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 428 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 487
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HTG G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 488 CQE--KKEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 545
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 546 TAKYL 550
Score = 98.3 bits (234), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1036 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1094
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1095 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1154
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1155 EMMRVVDDFNSNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1213
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1214 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1251
>AB209496-1|BAD92733.1| 1045|Homo sapiens brain adenylate cyclase 1
variant protein.
Length = 1045
Score = 113 bits (271), Expect = 5e-24
Identities = 67/192 (34%), Positives = 103/192 (53%), Gaps = 11/192 (5%)
Query: 877 QLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEF---------EEVSIYFSDIVGFTA 927
+L+ E +K E+LL +LPR+VA + PE + VSI F+DIVGFT
Sbjct: 242 RLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTG 301
Query: 928 LAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATM 987
LA++ TA ++V LLN+L+ FD + +++ +GD Y V GL Q DHA M
Sbjct: 302 LASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEM 361
Query: 988 ALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMEST 1047
L ++ V + L++R+GLHTG GV+GL +Y ++ + V A+ ME+
Sbjct: 362 GLDMIDTI--TSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAA 419
Query: 1048 GAAWRIQISSTT 1059
G ++ I+ TT
Sbjct: 420 GLPGKVHITKTT 431
Score = 90.6 bits (215), Expect = 3e-17
Identities = 61/202 (30%), Positives = 105/202 (51%), Gaps = 23/202 (11%)
Query: 876 EQLDMEKKKTE--QLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT--- 926
E+ DMEK K + ++L +LP VA+ ++ + + + + +V + F+ I F
Sbjct: 809 EREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFY 868
Query: 927 -ALAARSTAVQVVDLLNDLYTTFDAAIEQ--YR-VYKVETIGDAYMVVGGLPQRT----- 977
L + V+ + LLN++ FD +E+ Y+ + K++TIG YM GL +
Sbjct: 869 IELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAK 928
Query: 978 ---RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLF 1034
H ++A A+ + + + D LR+G++ GP AGV+G P+Y ++
Sbjct: 929 KSISSHLSTLADFAIEMFDVLDEINYQSYND--FVLRVGINVGPVVAGVIGARRPQYDIW 986
Query: 1035 GDTVNTASRMESTGAAWRIQIS 1056
G+TVN ASRM+STG RIQ++
Sbjct: 987 GNTVNVASRMDSTGVQGRIQVT 1008
>AJ133123-1|CAB65084.1| 1353|Homo sapiens adenylyl cyclase type IX
protein.
Length = 1353
Score = 111 bits (268), Expect = 1e-23
Identities = 70/245 (28%), Positives = 127/245 (51%), Gaps = 5/245 (2%)
Query: 819 VMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDSMFEMLEKYSNNLEELIRERTEQL 878
VM Q S + L+ + +H ++++ K ++ S+ + +++L + E +E
Sbjct: 300 VMSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRI--IADDLMKQGDEESEN- 356
Query: 879 DMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARSTAVQVV 938
+++ T NR S+ + + + ++ EEVSI F+DIVGFT ++A +A +V
Sbjct: 357 SVKRHATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALV 416
Query: 939 DLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESVATMALHLLHLAGRF 998
LLNDL+ FD E+ + K+ T+GD Y V G P+ DHA M L ++ +F
Sbjct: 417 GLLNDLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQF 476
Query: 999 RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISST 1058
+++R+G+HT G++G+ ++ ++ + VN A+ ME G A ++ IS
Sbjct: 477 CQE--KKEMVNMRVGVHTRTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEA 534
Query: 1059 TAEKL 1063
TA+ L
Sbjct: 535 TAKYL 539
Score = 98.3 bits (234), Expect = 2e-19
Identities = 67/219 (30%), Positives = 109/219 (49%), Gaps = 15/219 (6%)
Query: 882 KKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVSIYFSDIVGFTALAARST--AVQVVD 939
+ + + LL ++P VAE+L + S+ + + + F+ IV F+ + +
Sbjct: 1025 RDQADWLLRNIIPYHVAEQLKV-SQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKECYR 1083
Query: 940 LLNDLYTTFDAAIEQ---YRVYKVETIGDAYMVVGGLP-------QRTRDHAESVATMAL 989
+LN+L FD + + + K++TIG YM GL ++H + + A
Sbjct: 1084 VLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNTAQAQDGSHPQEHLQILFEFAK 1143
Query: 990 HLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGA 1049
++ + F L LR+G + GP AGV+G T Y ++GDTVN ASRM++TG
Sbjct: 1144 EMMRVVDDFNSNMLWFN-FKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTGV 1202
Query: 1050 AWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTY 1088
RIQ+S + ++L+ GY RG +KGKG M TY
Sbjct: 1203 ECRIQVSE-ESYRVLSKMGYDFDYRGTVNVKGKGQMKTY 1240
>L05500-1|AAA02907.1| 839|Homo sapiens adenylyl cyclase protein.
Length = 839
Score = 110 bits (265), Expect = 3e-23
Identities = 75/239 (31%), Positives = 123/239 (51%), Gaps = 24/239 (10%)
Query: 876 EQLDMEKKKTE--QLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT--- 926
E+ DMEK K + ++L +LP VA+ ++ + + + + +V + F+ I F
Sbjct: 542 EREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFY 601
Query: 927 -ALAARSTAVQVVDLLNDLYTTFDAAIEQ--YR-VYKVETIGDAYMVVGGLPQRT----- 977
L + V+ + LLN++ FD +E+ Y+ + K++TIG YM GL +
Sbjct: 602 IELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAK 661
Query: 978 ---RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLF 1034
H ++A A+ + + + D LR+G++ GP AGV+G P+Y ++
Sbjct: 662 KSISSHLSTLADFAIEMFDVLDEINYQSYND--FVLRVGINVGPVVAGVIGARRPQYDIW 719
Query: 1035 GDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWLLGK 1093
G+TVN ASRM+STG RIQ++ +LL Y RG +KGKG M TY+L G+
Sbjct: 720 GNTVNVASRMDSTGVQGRIQVTE-EVHRLLRRCPYHFVCRGKVSVKGKGEMLTYFLEGR 777
Score = 103 bits (247), Expect = 4e-21
Identities = 54/150 (36%), Positives = 84/150 (56%), Gaps = 2/150 (1%)
Query: 910 EEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMV 969
+ + VSI F+DIVGFT LA++ TA ++V LLN+L+ FD + +++ +GD Y
Sbjct: 17 QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC 76
Query: 970 VGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMP 1029
V GL Q DHA M L ++ V + L++R+GLHTG GV+GL
Sbjct: 77 VSGLTQPKTDHAHCCVEMGLDMIDTI--TSVAEATEVDLNMRVGLHTGRVLCGVLGLRKW 134
Query: 1030 RYCLFGDTVNTASRMESTGAAWRIQISSTT 1059
+Y ++ + V A+ ME+ G ++ I+ TT
Sbjct: 135 QYDVWSNDVTLANVMEAAGLPGKVHITKTT 164
>BC117475-1|AAI17476.1| 1077|Homo sapiens adenylate cyclase 4 protein.
Length = 1077
Score = 107 bits (258), Expect = 2e-22
Identities = 76/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT 926
+R+ E+ + + T LL +LP VA + + +R + + +E V + F+ + F
Sbjct: 824 LRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFK 883
Query: 927 ALAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRD 979
+ S ++ + LLN++ FD + + + V K++TIG YM GL +
Sbjct: 884 EFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQ 943
Query: 980 HAESVA--------TMALHLLHLAGRFRVRHLPD-TPLHLRIGLHTGPCCAGVVGLTMPR 1030
A+ A TM + L + V + LR+GL+ GP AGV+G P+
Sbjct: 944 DAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQ 1003
Query: 1031 YCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
Y ++G+TVN ASRMESTG +IQ++ TA L + GY SRG+ ++KGKG + TY+L
Sbjct: 1004 YDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL-GYTCYSRGVIKVKGKGQLCTYFL 1062
Score = 103 bits (247), Expect = 4e-21
Identities = 68/219 (31%), Positives = 108/219 (49%), Gaps = 23/219 (10%)
Query: 877 QLDMEKKKTEQLLNRMLPRSVAE--------RLMLGSRVEPEE-----------FEEVSI 917
+LD EKK E LL +LP +A RL G PE + VS+
Sbjct: 215 RLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSV 274
Query: 918 YFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRT 977
++DIVGFT LA+ + ++V +LN+L+ FD +++ +++ +GD Y V GLP
Sbjct: 275 LYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSL 334
Query: 978 RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDT 1037
DHA + M L + + R D +++R+G+H+G GV+GL +Y ++
Sbjct: 335 PDHAINCVRMGLDMCRAIRKLRAATGVD--INMRVGVHSGSVLCGVIGLQKWQYDVWSHD 392
Query: 1038 VNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGL 1076
V A+ ME+ G R+ I+ T L AG Y + G+
Sbjct: 393 VTLANHMEAGGVPGRVHITGATL--ALLAGAYAVEDAGM 429
>BC117473-1|AAI17474.1| 1077|Homo sapiens adenylate cyclase 4 protein.
Length = 1077
Score = 107 bits (258), Expect = 2e-22
Identities = 76/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT 926
+R+ E+ + + T LL +LP VA + + +R + + +E V + F+ + F
Sbjct: 824 LRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFK 883
Query: 927 ALAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRD 979
+ S ++ + LLN++ FD + + + V K++TIG YM GL +
Sbjct: 884 EFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQ 943
Query: 980 HAESVA--------TMALHLLHLAGRFRVRHLPD-TPLHLRIGLHTGPCCAGVVGLTMPR 1030
A+ A TM + L + V + LR+GL+ GP AGV+G P+
Sbjct: 944 DAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQ 1003
Query: 1031 YCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
Y ++G+TVN ASRMESTG +IQ++ TA L + GY SRG+ ++KGKG + TY+L
Sbjct: 1004 YDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL-GYTCYSRGVIKVKGKGQLCTYFL 1062
Score = 103 bits (247), Expect = 4e-21
Identities = 68/219 (31%), Positives = 108/219 (49%), Gaps = 23/219 (10%)
Query: 877 QLDMEKKKTEQLLNRMLPRSVAE--------RLMLGSRVEPEE-----------FEEVSI 917
+LD EKK E LL +LP +A RL G PE + VS+
Sbjct: 215 RLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSV 274
Query: 918 YFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRT 977
++DIVGFT LA+ + ++V +LN+L+ FD +++ +++ +GD Y V GLP
Sbjct: 275 LYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSL 334
Query: 978 RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDT 1037
DHA + M L + + R D +++R+G+H+G GV+GL +Y ++
Sbjct: 335 PDHAINCVRMGLDMCRAIRKLRAATGVD--INMRVGVHSGSVLCGVIGLQKWQYDVWSHD 392
Query: 1038 VNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGL 1076
V A+ ME+ G R+ I+ T L AG Y + G+
Sbjct: 393 VTLANHMEAGGVPGRVHITGATL--ALLAGAYAVEDAGM 429
>AK056745-1|BAB71270.1| 506|Homo sapiens protein ( Homo sapiens cDNA
FLJ32183 fis, clone PLACE6001886, highly similar to
ADENYLATE CYCLASE, TYPE IV (EC 4.6.1.1). ).
Length = 506
Score = 107 bits (258), Expect = 2e-22
Identities = 76/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT 926
+R+ E+ + + T LL +LP VA + + +R + + +E V + F+ + F
Sbjct: 253 LRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFK 312
Query: 927 ALAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRD 979
+ S ++ + LLN++ FD + + + V K++TIG YM GL +
Sbjct: 313 EFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQ 372
Query: 980 HAESVA--------TMALHLLHLAGRFRVRHLPD-TPLHLRIGLHTGPCCAGVVGLTMPR 1030
A+ A TM + L + V + LR+GL+ GP AGV+G P+
Sbjct: 373 DAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQ 432
Query: 1031 YCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
Y ++G+TVN ASRMESTG +IQ++ TA L + GY SRG+ ++KGKG + TY+L
Sbjct: 433 YDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL-GYTCYSRGVIKVKGKGQLCTYFL 491
>AF497516-1|AAM94373.1| 1077|Homo sapiens adenylate cyclase type IV
protein.
Length = 1077
Score = 107 bits (258), Expect = 2e-22
Identities = 76/240 (31%), Positives = 123/240 (51%), Gaps = 21/240 (8%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSR----VEPEEFEEVSIYFSDIVGFT 926
+R+ E+ + + T LL +LP VA + + +R + + +E V + F+ + F
Sbjct: 824 LRQEREETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFK 883
Query: 927 ALAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQRTRD 979
+ S ++ + LLN++ FD + + + V K++TIG YM GL +
Sbjct: 884 EFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQ 943
Query: 980 HAESVA--------TMALHLLHLAGRFRVRHLPD-TPLHLRIGLHTGPCCAGVVGLTMPR 1030
A+ A TM + L + V + LR+GL+ GP AGV+G P+
Sbjct: 944 DAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQ 1003
Query: 1031 YCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
Y ++G+TVN ASRMESTG +IQ++ TA L + GY SRG+ ++KGKG + TY+L
Sbjct: 1004 YDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL-GYTCYSRGVIKVKGKGQLCTYFL 1062
Score = 103 bits (247), Expect = 4e-21
Identities = 68/219 (31%), Positives = 108/219 (49%), Gaps = 23/219 (10%)
Query: 877 QLDMEKKKTEQLLNRMLPRSVAE--------RLMLGSRVEPEE-----------FEEVSI 917
+LD EKK E LL +LP +A RL G PE + VS+
Sbjct: 215 RLDTEKKHQEHLLLSILPAYLAREMKAEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSV 274
Query: 918 YFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRT 977
++DIVGFT LA+ + ++V +LN+L+ FD +++ +++ +GD Y V GLP
Sbjct: 275 LYADIVGFTRLASECSPKELVLMLNELFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSL 334
Query: 978 RDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDT 1037
DHA + M L + + R D +++R+G+H+G GV+GL +Y ++
Sbjct: 335 PDHAINCVRMGLDMCRAIRKLRAATGVD--INMRVGVHSGSVLCGVIGLQKWQYDVWSHD 392
Query: 1038 VNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGL 1076
V A+ ME+ G R+ I+ T L AG Y + G+
Sbjct: 393 VTLANHMEAGGVPGRVHITGATL--ALLAGAYAVEDAGM 429
>BC126235-1|AAI26236.1| 1144|Homo sapiens adenylate cyclase 3 protein.
Length = 1144
Score = 105 bits (252), Expect = 1e-21
Identities = 63/199 (31%), Positives = 109/199 (54%), Gaps = 15/199 (7%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERLMLG-----SRVEPEEF--------EEVSIYFSDIVG 924
L+ + ++ E L+ +LP+ VA+ ++ S+ + ++F E VSI F+DIVG
Sbjct: 268 LEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVG 327
Query: 925 FTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESV 984
FT L++ +A ++V LLN+L+ FD +Y +++ +GD Y + GLP DHA V
Sbjct: 328 FTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHA--V 385
Query: 985 ATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRM 1044
++ + L + VR T + +R+G+HTG GV+G +Y ++ V A++M
Sbjct: 386 CSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKM 445
Query: 1045 ESTGAAWRIQISSTTAEKL 1063
E+ G R+ IS +T + L
Sbjct: 446 EAGGIPGRVHISQSTMDCL 464
Score = 97.5 bits (232), Expect = 3e-19
Identities = 72/252 (28%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEE-----FEEVSIYFSDIVGF 925
+ ++ E++ ++ E L+ MLP VA R LGS+ EE ++E+ + F+ + F
Sbjct: 874 VHDQKERVYEMRRWNEALVTNMLPEHVA-RHFLGSKKRDEELYSQTYDEIGVMFASLPNF 932
Query: 926 ----TALAARSTAVQVVDLLNDLYTTFDAAIE--QYRVY-KVETIGDAYMVVGGLP---- 974
T + + ++ + LN++ + FD+ ++ ++RV K++TIG YM G+
Sbjct: 933 ADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN 992
Query: 975 -----------QRTRDHAESVATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAG 1022
+ R+ + +A +A L + + + LRIG++ G AG
Sbjct: 993 TNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 1052
Query: 1023 VVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGK 1082
V+G P Y ++G+TVN ASRMESTG IQ+ T + +L G++ RG +KGK
Sbjct: 1053 VIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEET-QVILREYGFRFVRRGPIFVKGK 1111
Query: 1083 GAMHTYWLLGKE 1094
G + T++L G++
Sbjct: 1112 GELLTFFLKGRD 1123
>AF033861-1|AAD13403.1| 1144|Homo sapiens type III adenylyl cyclase
protein.
Length = 1144
Score = 105 bits (252), Expect = 1e-21
Identities = 63/199 (31%), Positives = 109/199 (54%), Gaps = 15/199 (7%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERLMLG-----SRVEPEEF--------EEVSIYFSDIVG 924
L+ + ++ E L+ +LP+ VA+ ++ S+ + ++F E VSI F+DIVG
Sbjct: 268 LEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVG 327
Query: 925 FTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESV 984
FT L++ +A ++V LLN+L+ FD +Y +++ +GD Y + GLP DHA V
Sbjct: 328 FTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHA--V 385
Query: 985 ATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRM 1044
++ + L + VR T + +R+G+HTG GV+G +Y ++ V A++M
Sbjct: 386 CSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKM 445
Query: 1045 ESTGAAWRIQISSTTAEKL 1063
E+ G R+ IS +T + L
Sbjct: 446 EAGGIPGRVHISQSTMDCL 464
Score = 97.5 bits (232), Expect = 3e-19
Identities = 72/252 (28%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEE-----FEEVSIYFSDIVGF 925
+ ++ E++ ++ E L+ MLP VA R LGS+ EE ++E+ + F+ + F
Sbjct: 874 VHDQKERVYEMRRWNEALVTNMLPEHVA-RHFLGSKKRDEELYSQTYDEIGVMFASLPNF 932
Query: 926 ----TALAARSTAVQVVDLLNDLYTTFDAAIE--QYRVY-KVETIGDAYMVVGGLP---- 974
T + + ++ + LN++ + FD+ ++ ++RV K++TIG YM G+
Sbjct: 933 ADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN 992
Query: 975 -----------QRTRDHAESVATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAG 1022
+ R+ + +A +A L + + + LRIG++ G AG
Sbjct: 993 TNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 1052
Query: 1023 VVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGK 1082
V+G P Y ++G+TVN ASRMESTG IQ+ T + +L G++ RG +KGK
Sbjct: 1053 VIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEET-QVILREYGFRFVRRGPIFVKGK 1111
Query: 1083 GAMHTYWLLGKE 1094
G + T++L G++
Sbjct: 1112 GELLTFFLKGRD 1123
>AC012073-2|AAY14787.1| 1144|Homo sapiens unknown protein.
Length = 1144
Score = 105 bits (252), Expect = 1e-21
Identities = 63/199 (31%), Positives = 109/199 (54%), Gaps = 15/199 (7%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERLMLG-----SRVEPEEF--------EEVSIYFSDIVG 924
L+ + ++ E L+ +LP+ VA+ ++ S+ + ++F E VSI F+DIVG
Sbjct: 268 LEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVG 327
Query: 925 FTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESV 984
FT L++ +A ++V LLN+L+ FD +Y +++ +GD Y + GLP DHA V
Sbjct: 328 FTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHA--V 385
Query: 985 ATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRM 1044
++ + L + VR T + +R+G+HTG GV+G +Y ++ V A++M
Sbjct: 386 CSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKM 445
Query: 1045 ESTGAAWRIQISSTTAEKL 1063
E+ G R+ IS +T + L
Sbjct: 446 EAGGIPGRVHISQSTMDCL 464
Score = 97.5 bits (232), Expect = 3e-19
Identities = 72/252 (28%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEE-----FEEVSIYFSDIVGF 925
+ ++ E++ ++ E L+ MLP VA R LGS+ EE ++E+ + F+ + F
Sbjct: 874 VHDQKERVYEMRRWNEALVTNMLPEHVA-RHFLGSKKRDEELYSQTYDEIGVMFASLPNF 932
Query: 926 ----TALAARSTAVQVVDLLNDLYTTFDAAIE--QYRVY-KVETIGDAYMVVGGLP---- 974
T + + ++ + LN++ + FD+ ++ ++RV K++TIG YM G+
Sbjct: 933 ADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN 992
Query: 975 -----------QRTRDHAESVATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAG 1022
+ R+ + +A +A L + + + LRIG++ G AG
Sbjct: 993 TNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 1052
Query: 1023 VVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGK 1082
V+G P Y ++G+TVN ASRMESTG IQ+ T + +L G++ RG +KGK
Sbjct: 1053 VIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEET-QVILREYGFRFVRRGPIFVKGK 1111
Query: 1083 GAMHTYWLLGKE 1094
G + T++L G++
Sbjct: 1112 GELLTFFLKGRD 1123
>AB011083-1|BAA25437.1| 933|Homo sapiens KIAA0511 protein protein.
Length = 933
Score = 105 bits (252), Expect = 1e-21
Identities = 63/199 (31%), Positives = 109/199 (54%), Gaps = 15/199 (7%)
Query: 878 LDMEKKKTEQLLNRMLPRSVAERLMLG-----SRVEPEEF--------EEVSIYFSDIVG 924
L+ + ++ E L+ +LP+ VA+ ++ S+ + ++F E VSI F+DIVG
Sbjct: 57 LEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVG 116
Query: 925 FTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAESV 984
FT L++ +A ++V LLN+L+ FD +Y +++ +GD Y + GLP DHA V
Sbjct: 117 FTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHA--V 174
Query: 985 ATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRM 1044
++ + L + VR T + +R+G+HTG GV+G +Y ++ V A++M
Sbjct: 175 CSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKM 234
Query: 1045 ESTGAAWRIQISSTTAEKL 1063
E+ G R+ IS +T + L
Sbjct: 235 EAGGIPGRVHISQSTMDCL 253
Score = 97.5 bits (232), Expect = 3e-19
Identities = 72/252 (28%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEE-----FEEVSIYFSDIVGF 925
+ ++ E++ ++ E L+ MLP VA R LGS+ EE ++E+ + F+ + F
Sbjct: 663 VHDQKERVYEMRRWNEALVTNMLPEHVA-RHFLGSKKRDEELYSQTYDEIGVMFASLPNF 721
Query: 926 ----TALAARSTAVQVVDLLNDLYTTFDAAIE--QYRVY-KVETIGDAYMVVGGLP---- 974
T + + ++ + LN++ + FD+ ++ ++RV K++TIG YM G+
Sbjct: 722 ADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN 781
Query: 975 -----------QRTRDHAESVATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAG 1022
+ R+ + +A +A L + + + LRIG++ G AG
Sbjct: 782 TNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 841
Query: 1023 VVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGK 1082
V+G P Y ++G+TVN ASRMESTG IQ+ T + +L G++ RG +KGK
Sbjct: 842 VIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEET-QVILREYGFRFVRRGPIFVKGK 900
Query: 1083 GAMHTYWLLGKE 1094
G + T++L G++
Sbjct: 901 GELLTFFLKGRD 912
>DQ104739-1|AAZ13596.1| 1120|Homo sapiens brain adenylate cyclase 8
protein.
Length = 1120
Score = 104 bits (250), Expect = 2e-21
Identities = 60/186 (32%), Positives = 100/186 (53%), Gaps = 7/186 (3%)
Query: 906 RVEPEEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGD 965
R+ +E VSI F+D+ GFT L+A +A ++V +LN+L+ FD + ++ +++ +GD
Sbjct: 404 RIYIHRYENVSILFADVKGFTNLSATLSAQELVRMLNELFARFDRLVHEHHCLRIKILGD 463
Query: 966 AYMVVGGLPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVG 1025
Y V GLP+ +DHA M L ++ R R D + +RIG+H+G GV+G
Sbjct: 464 CYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHD--VDMRIGIHSGSVLCGVLG 521
Query: 1026 LTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKL---RSRGLTQIKGK 1082
L ++ ++ V+ A+++ES G RI IS T + L G Y + + + GK
Sbjct: 522 LRKWQFDVWSWDVDIANKLESGGIPGRIHISEATLDCL--NGDYNVEEGHGKERNEFLGK 579
Query: 1083 GAMHTY 1088
+ TY
Sbjct: 580 HNIETY 585
Score = 93.9 bits (223), Expect = 3e-18
Identities = 71/241 (29%), Positives = 116/241 (48%), Gaps = 20/241 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPE----EFEEVSIYFSDIVGFTA 927
+E ++ ++ E +L +LP VA + + E ++ V + F+ I GF
Sbjct: 803 KEEINEMKELREHNENMLRNILPSHVARHFLEKDQDNEELYSQSYDAVGVMFASIPGFAD 862
Query: 928 LAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLP---QRT 977
+++ V+ + LLN++ FD + + R + K++TIG YM V G Q+
Sbjct: 863 FYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGPSPEKQQC 922
Query: 978 RDHAESVATMALHLLHLAGRFR-VRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGD 1036
D + +A L L + + LRIG+ G AGV+G P+Y ++G
Sbjct: 923 EDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGK 982
Query: 1037 TVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKG----KGAMHTYWLLG 1092
TVN ASRM+STG + RIQ+ T +L G+ RG +KG +G + TY+LLG
Sbjct: 983 TVNLASRMDSTGVSGRIQVPEET-YLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLG 1041
Query: 1093 K 1093
+
Sbjct: 1042 R 1042
>X74210-1|CAA52282.1| 476|Homo sapiens adenylate cyclase protein.
Length = 476
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 224 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 283
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 284 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 343
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 344 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 403
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 404 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 461
>L21993-1|AAA64923.1| 476|Homo sapiens adenylyl cyclase protein.
Length = 476
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 224 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 283
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 284 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 343
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 344 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 403
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 404 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 461
>BC111743-1|AAI11744.1| 1091|Homo sapiens adenylate cyclase 2 (brain)
protein.
Length = 1091
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 839 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 898
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 899 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 958
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 959 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 1018
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 1019 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 1076
Score = 99 bits (238), Expect = 5e-20
Identities = 54/157 (34%), Positives = 88/157 (56%), Gaps = 4/157 (2%)
Query: 915 VSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLP 974
VSI ++DIVGFT LA+ + ++V +LN+L+ FD ++ +++ +GD Y V GLP
Sbjct: 289 VSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLP 348
Query: 975 QRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLF 1034
+HA++ M L + +VR +++R+G+H+G GV+GL +Y ++
Sbjct: 349 ISLPNHAKNCVKMGLDMCEAIK--KVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVW 406
Query: 1035 GDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKL 1071
V A+ ME+ G R+ ISS T E L G YK+
Sbjct: 407 SHDVTLANHMEAGGVPGRVHISSVTLEHL--NGAYKV 441
>AF410885-1|AAP97285.1| 1091|Homo sapiens adenylyl cyclase type II
protein.
Length = 1091
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 839 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 898
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 899 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 958
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 959 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 1018
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 1019 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 1076
Score = 99 bits (238), Expect = 5e-20
Identities = 54/157 (34%), Positives = 88/157 (56%), Gaps = 4/157 (2%)
Query: 915 VSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLP 974
VSI ++DIVGFT LA+ + ++V +LN+L+ FD ++ +++ +GD Y V GLP
Sbjct: 289 VSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLP 348
Query: 975 QRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLF 1034
+HA++ M L + +VR +++R+G+H+G GV+GL +Y ++
Sbjct: 349 ISLPNHAKNCVKMGLDMCEAIK--KVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVW 406
Query: 1035 GDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKL 1071
V A+ ME+ G R+ ISS T E L G YK+
Sbjct: 407 SHDVTLANHMEAGGVPGRVHISSVTLEHL--NGAYKV 441
>AF070583-1|AAC28647.1| 367|Homo sapiens adenylyl cyclase protein.
Length = 367
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 115 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 174
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 175 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 234
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 235 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 294
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 295 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 352
>AB028983-1|BAA83012.1| 887|Homo sapiens KIAA1060 protein protein.
Length = 887
Score = 102 bits (245), Expect = 7e-21
Identities = 70/239 (29%), Positives = 119/239 (49%), Gaps = 21/239 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDIVGFTA 927
++ E+++ + LL +LP VAE + S E + + V + F+ I F
Sbjct: 635 KKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKE 694
Query: 928 LAARSTA----VQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLPQ-RTRD 979
S ++ + LLN++ FD + + + V K++TIG YM GL +++
Sbjct: 695 FYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQE 754
Query: 980 HAES-------VATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRY 1031
H++ + TM L G+ + LR+G++ GP AGV+G P+Y
Sbjct: 755 HSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQY 814
Query: 1032 CLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRM+STG +IQ++ T+ +L GY RG+ +KGKG + TY++
Sbjct: 815 DIWGNTVNVASRMDSTGVLDKIQVTEETS-LVLQTLGYTCTCRGIINVKGKGDLKTYFV 872
Score = 99 bits (238), Expect = 5e-20
Identities = 54/157 (34%), Positives = 88/157 (56%), Gaps = 4/157 (2%)
Query: 915 VSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLP 974
VSI ++DIVGFT LA+ + ++V +LN+L+ FD ++ +++ +GD Y V GLP
Sbjct: 85 VSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLP 144
Query: 975 QRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLF 1034
+HA++ M L + +VR +++R+G+H+G GV+GL +Y ++
Sbjct: 145 ISLPNHAKNCVKMGLDMCEAIK--KVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVW 202
Query: 1035 GDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKL 1071
V A+ ME+ G R+ ISS T E L G YK+
Sbjct: 203 SHDVTLANHMEAGGVPGRVHISSVTLEHL--NGAYKV 237
>Z35309-1|CAA84552.1| 1251|Homo sapiens adenylyl cyclase protein.
Length = 1251
Score = 102 bits (244), Expect = 9e-21
Identities = 64/200 (32%), Positives = 107/200 (53%), Gaps = 15/200 (7%)
Query: 877 QLDMEKKKTEQLLNRMLPRSVA-ERLMLGSRVEPEE------------FEEVSIYFSDIV 923
+L+ E ++ E+L+ +LPR V E + + VE E +E VSI F+D+
Sbjct: 362 RLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVK 421
Query: 924 GFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGGLPQRTRDHAES 983
GFT L+ +A ++V +LN+L+ FD ++ +++ +GD Y V GLP+ +DHA
Sbjct: 422 GFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHC 481
Query: 984 VATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASR 1043
M L ++ R R D + +RIG+H+G GV+GL ++ ++ V+ A++
Sbjct: 482 CVEMGLSMIKTIRYVRSRTKHD--VDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANK 539
Query: 1044 MESTGAAWRIQISSTTAEKL 1063
+ES G RI IS T + L
Sbjct: 540 LESGGIPGRIHISKATLDCL 559
Score = 98.3 bits (234), Expect = 2e-19
Identities = 73/241 (30%), Positives = 117/241 (48%), Gaps = 20/241 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPE----EFEEVSIYFSDIVGFTA 927
+E ++ ++ E +L +LP VA + R E ++ V + F+ I GF
Sbjct: 934 KEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFAD 993
Query: 928 LAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLP---QRT 977
+++ V+ + LLN++ FD + + R + K++TIG YM V GL Q+
Sbjct: 994 FYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQC 1053
Query: 978 RDHAESVATMALHLLHLAGRFR-VRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGD 1036
D + +A L L + + LRIG+ G AGV+G P+Y ++G
Sbjct: 1054 EDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGK 1113
Query: 1037 TVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKG----KGAMHTYWLLG 1092
TVN ASRM+STG + RIQ+ T +L G+ RG +KG +G + TY+LLG
Sbjct: 1114 TVNLASRMDSTGVSGRIQVPEET-YLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLG 1172
Query: 1093 K 1093
+
Sbjct: 1173 R 1173
>D25538-1|BAA05021.2| 1088|Homo sapiens KIAA0037 protein.
Length = 1088
Score = 100 bits (240), Expect = 3e-20
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 21/238 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDI----V 923
++ E+ + + LL +LP VA +G ++ + + + V + F+ + V
Sbjct: 840 KKEHEEFETMENVNRLLLENVLPAHVAAHF-IGDKLNEDWYHQSYDCVCVMFASVPDFKV 898
Query: 924 GFTALAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLP------ 974
+T ++ + LLN++ FD + + + V K++TIG YM GL
Sbjct: 899 FYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHE 958
Query: 975 --QRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYC 1032
+ R HA + + ++ + LR+G++ GP AGV+G P+Y
Sbjct: 959 NQELERQHAHIGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYD 1018
Query: 1033 LFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRMESTG +IQ++ T +L GY RGL +KGKG + TY++
Sbjct: 1019 IWGNTVNVASRMESTGELGKIQVTEETC-TILQGLGYSCECRGLINVKGKGELRTYFV 1075
Score = 95.5 bits (227), Expect = 1e-18
Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%)
Query: 913 EEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGG 972
+ VSI ++DIVGFT LA+ + ++V +LN+L+ FD + +++ +GD Y V G
Sbjct: 284 QNVSILYADIVGFTQLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSG 343
Query: 973 LPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYC 1032
LP HA + M L + +VR +++R+G+H+G GV+GL +Y
Sbjct: 344 LPVSLPTHARNCVKMGLDMCQAIK--QVREATGVDINMRVGIHSGNVLCGVIGLRKWQYD 401
Query: 1033 LFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
++ V+ A+RME+ G R+ I+ T + L
Sbjct: 402 VWSHDVSLANRMEAAGVPGRVHITEATLKHL 432
>BC126271-1|AAI26272.1| 1080|Homo sapiens adenylate cyclase 7 protein.
Length = 1080
Score = 100 bits (240), Expect = 3e-20
Identities = 67/238 (28%), Positives = 115/238 (48%), Gaps = 21/238 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEE----VSIYFSDI----V 923
++ E+ + + LL +LP VA +G ++ + + + V + F+ + V
Sbjct: 832 KKEHEEFETMENVNRLLLENVLPAHVAAHF-IGDKLNEDWYHQSYDCVCVMFASVPDFKV 890
Query: 924 GFTALAARSTAVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLP------ 974
+T ++ + LLN++ FD + + + V K++TIG YM GL
Sbjct: 891 FYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAAAGLSVASGHE 950
Query: 975 --QRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYC 1032
+ R HA + + ++ + LR+G++ GP AGV+G P+Y
Sbjct: 951 NQELERQHAHIGVMVEFSIALMSKLDGINRHSFNSFRLRVGINHGPVIAGVIGARKPQYD 1010
Query: 1033 LFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGKGAMHTYWL 1090
++G+TVN ASRMESTG +IQ++ T +L GY RGL +KGKG + TY++
Sbjct: 1011 IWGNTVNVASRMESTGELGKIQVTEETC-TILQGLGYSCECRGLINVKGKGELRTYFV 1067
Score = 95.5 bits (227), Expect = 1e-18
Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%)
Query: 913 EEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGG 972
+ VSI ++DIVGFT LA+ + ++V +LN+L+ FD + +++ +GD Y V G
Sbjct: 276 QNVSILYADIVGFTQLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSG 335
Query: 973 LPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYC 1032
LP HA + M L + +VR +++R+G+H+G GV+GL +Y
Sbjct: 336 LPVSLPTHARNCVKMGLDMCQAIK--QVREATGVDINMRVGIHSGNVLCGVIGLRKWQYD 393
Query: 1033 LFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
++ V+ A+RME+ G R+ I+ T + L
Sbjct: 394 VWSHDVSLANRMEAAGVPGRVHITEATLKHL 424
>M83533-1|AAA35523.2| 675|Homo sapiens adenylyl cyclase type V
protein.
Length = 675
Score = 98.3 bits (234), Expect = 2e-19
Identities = 73/241 (30%), Positives = 117/241 (48%), Gaps = 20/241 (8%)
Query: 872 RERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPE----EFEEVSIYFSDIVGFTA 927
+E ++ ++ E +L +LP VA + R E ++ V + F+ I GF
Sbjct: 358 KEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFAD 417
Query: 928 LAARST----AVQVVDLLNDLYTTFDAAIEQYR---VYKVETIGDAYMVVGGLP---QRT 977
+++ V+ + LLN++ FD + + R + K++TIG YM V GL Q+
Sbjct: 418 FYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQC 477
Query: 978 RDHAESVATMALHLLHLAGRFR-VRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYCLFGD 1036
D + +A L L + + LRIG+ G AGV+G P+Y ++G
Sbjct: 478 EDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGK 537
Query: 1037 TVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKG----KGAMHTYWLLG 1092
TVN ASRM+STG + RIQ+ T +L G+ RG +KG +G + TY+LLG
Sbjct: 538 TVNLASRMDSTGVSGRIQVPEET-YLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLG 596
Query: 1093 K 1093
+
Sbjct: 597 R 597
>AK075424-1|BAC11613.1| 378|Homo sapiens protein ( Homo sapiens cDNA
PSEC0115 fis, clone PLACE1000086, highly similar to
ADENYLATE CYCLASE, OLFACTIVE TYPE (EC 4.6.1.1). ).
Length = 378
Score = 97.5 bits (232), Expect = 3e-19
Identities = 72/252 (28%), Positives = 128/252 (50%), Gaps = 30/252 (11%)
Query: 871 IRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEE-----FEEVSIYFSDIVGF 925
+ ++ E++ ++ E L+ MLP VA R LGS+ EE ++E+ + F+ + F
Sbjct: 108 VHDQKERVYEMRRWNEALVTNMLPEHVA-RHFLGSKKRDEELYSQTYDEIGVMFASLPNF 166
Query: 926 ----TALAARSTAVQVVDLLNDLYTTFDAAIE--QYRVY-KVETIGDAYMVVGGLP---- 974
T + + ++ + LN++ + FD+ ++ ++RV K++TIG YM G+
Sbjct: 167 ADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVN 226
Query: 975 -----------QRTRDHAESVATMALHLLHLAGRF-RVRHLPDTPLHLRIGLHTGPCCAG 1022
+ R+ + +A +A L + + + LRIG++ G AG
Sbjct: 227 TNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAG 286
Query: 1023 VVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGYKLRSRGLTQIKGK 1082
V+G P Y ++G+TVN ASRMESTG IQ+ T + +L G++ RG +KGK
Sbjct: 287 VIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEET-QVILREYGFRFVRRGPIFVKGK 345
Query: 1083 GAMHTYWLLGKE 1094
G + T++L G++
Sbjct: 346 GELLTFFLKGRD 357
>BC039891-1|AAH39891.1| 433|Homo sapiens ADCY7 protein protein.
Length = 433
Score = 95.5 bits (227), Expect = 1e-18
Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%)
Query: 913 EEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMVVGG 972
+ VSI ++DIVGFT LA+ + ++V +LN+L+ FD + +++ +GD Y V G
Sbjct: 276 QNVSILYADIVGFTQLASDCSPKELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSG 335
Query: 973 LPQRTRDHAESVATMALHLLHLAGRFRVRHLPDTPLHLRIGLHTGPCCAGVVGLTMPRYC 1032
LP HA + M L + +VR +++R+G+H+G GV+GL +Y
Sbjct: 336 LPVSLPTHARNCVKMGLDMCQAIK--QVREATGVDINMRVGIHSGNVLCGVIGLRKWQYD 393
Query: 1033 LFGDTVNTASRMESTGAAWRIQISSTTAEKL 1063
++ V+ A+RME+ G R+ I+ T + L
Sbjct: 394 VWSHDVSLANRMEAAGVPGRVHITEATLKHL 424
>BC015982-1|AAH15982.2| 130|Homo sapiens ADCY4 protein protein.
Length = 130
Score = 84.2 bits (199), Expect = 3e-15
Identities = 41/81 (50%), Positives = 57/81 (70%), Gaps = 1/81 (1%)
Query: 1010 LRIGLHTGPCCAGVVGLTMPRYCLFGDTVNTASRMESTGAAWRIQISSTTAEKLLAAGGY 1069
LR+GL+ GP AGV+G P+Y ++G+TVN ASRMESTG +IQ++ TA L + GY
Sbjct: 36 LRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQVTEETAWALQSL-GY 94
Query: 1070 KLRSRGLTQIKGKGAMHTYWL 1090
SRG+ ++KGKG + TY+L
Sbjct: 95 TCYSRGVIKVKGKGQLCTYFL 115
>U50062-1|AAC32232.1| 671|Homo sapiens RIP protein kinase protein.
Length = 671
Score = 79.4 bits (187), Expect = 7e-14
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 18/265 (6%)
Query: 627 LMQNLRQENVNPFIGCLCE-GRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M LR V +G + E G+ +LV + +G+L VL A+ + + + ++ ++++
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-MSTPLSVKGRIILEIIE 124
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTP-RELLWTA 744
GM YLHG + H L N +VD+ + +++ D GL + L + RE+ TA
Sbjct: 125 GMCYLHGKGV-IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTA 183
Query: 745 PE-------LIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLC 797
+ + E T+ DV+SFA+++ + EPY + +++I +C
Sbjct: 184 KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY-ENAICEQQLI--MC 240
Query: 798 RPPPLIRPSVS--MGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
RP V P E +S+M+ CW P+ RP F + + FR + V+
Sbjct: 241 IKSG-NRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 856 MFEMLEK-YSNNLEELIRERTEQLD 879
+ L+K YSN + R ++ QLD
Sbjct: 300 DVKSLKKEYSNENAVVKRMQSLQLD 324
>BC126256-1|AAI26257.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 79.4 bits (187), Expect = 7e-14
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 18/265 (6%)
Query: 627 LMQNLRQENVNPFIGCLCE-GRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M LR V +G + E G+ +LV + +G+L VL A+ + + + ++ ++++
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-MSTPLSVKGRIILEIIE 124
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTP-RELLWTA 744
GM YLHG + H L N +VD+ + +++ D GL + L + RE+ TA
Sbjct: 125 GMCYLHGKGV-IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTA 183
Query: 745 PE-------LIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLC 797
+ + E T+ DV+SFA+++ + EPY + +++I +C
Sbjct: 184 KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY-ENAICEQQLI--MC 240
Query: 798 RPPPLIRPSVS--MGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
RP V P E +S+M+ CW P+ RP F + + FR + V+
Sbjct: 241 IKSG-NRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 856 MFEMLEK-YSNNLEELIRERTEQLD 879
+ L+K YSN + R ++ QLD
Sbjct: 300 DVKSLKKEYSNENAVVKRMQSLQLD 324
>BC126254-1|AAI26255.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 79.4 bits (187), Expect = 7e-14
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 18/265 (6%)
Query: 627 LMQNLRQENVNPFIGCLCE-GRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M LR V +G + E G+ +LV + +G+L VL A+ + + + ++ ++++
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-MSTPLSVKGRIILEIIE 124
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTP-RELLWTA 744
GM YLHG + H L N +VD+ + +++ D GL + L + RE+ TA
Sbjct: 125 GMCYLHGKGV-IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTA 183
Query: 745 PE-------LIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLC 797
+ + E T+ DV+SFA+++ + EPY + +++I +C
Sbjct: 184 KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY-ENAICEQQLI--MC 240
Query: 798 RPPPLIRPSVS--MGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
RP V P E +S+M+ CW P+ RP F + + FR + V+
Sbjct: 241 IKSG-NRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 856 MFEMLEK-YSNNLEELIRERTEQLD 879
+ L+K YSN + R ++ QLD
Sbjct: 300 DVKSLKKEYSNENAVVKRMQSLQLD 324
>AY682848-1|AAT74626.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 79.4 bits (187), Expect = 7e-14
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 18/265 (6%)
Query: 627 LMQNLRQENVNPFIGCLCE-GRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M LR V +G + E G+ +LV + +G+L VL A+ + + + ++ ++++
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-MSTPLSVKGRIILEIIE 124
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTP-RELLWTA 744
GM YLHG + H L N +VD+ + +++ D GL + L + RE+ TA
Sbjct: 125 GMCYLHGKGV-IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTA 183
Query: 745 PE-------LIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLC 797
+ + E T+ DV+SFA+++ + EPY + +++I +C
Sbjct: 184 KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY-ENAICEQQLI--MC 240
Query: 798 RPPPLIRPSVS--MGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
RP V P E +S+M+ CW P+ RP F + + FR + V+
Sbjct: 241 IKSG-NRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 856 MFEMLEK-YSNNLEELIRERTEQLD 879
+ L+K YSN + R ++ QLD
Sbjct: 300 DVKSLKKEYSNENAVVKRMQSLQLD 324
>AL031963-3|CAD70625.1| 671|Homo sapiens receptor
(TNFRSF)-interacting serine-threonine kinase 1 protein.
Length = 671
Score = 79.4 bits (187), Expect = 7e-14
Identities = 70/265 (26%), Positives = 124/265 (46%), Gaps = 18/265 (6%)
Query: 627 LMQNLRQENVNPFIGCLCE-GRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M LR V +G + E G+ +LV + +G+L VL A+ + + + ++ ++++
Sbjct: 66 MMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAE-MSTPLSVKGRIILEIIE 124
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTP-RELLWTA 744
GM YLHG + H L N +VD+ + +++ D GL + L + RE+ TA
Sbjct: 125 GMCYLHGKGV-IHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTA 183
Query: 745 PE-------LIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLC 797
+ + E T+ DV+SFA+++ + EPY + +++I +C
Sbjct: 184 KKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPY-ENAICEQQLI--MC 240
Query: 798 RPPPLIRPSVS--MGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
RP V P E +S+M+ CW P+ RP F + + FR + V+
Sbjct: 241 IKSG-NRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEE 299
Query: 856 MFEMLEK-YSNNLEELIRERTEQLD 879
+ L+K YSN + R ++ QLD
Sbjct: 300 DVKSLKKEYSNENAVVKRMQSLQLD 324
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 76.6 bits (180), Expect = 5e-13
Identities = 61/222 (27%), Positives = 98/222 (44%), Gaps = 16/222 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIK-LDWTFRLSLLSDLVK 685
++ LR E + G P + E R G+L+ L + + L L + +
Sbjct: 277 LKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAE 336
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM YL + H L++RN +VD +V D+GL L + P+ + + WTAP
Sbjct: 337 GMSYLEEQRV-VHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAP 395
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E + +Q DV+SF +++ EV G+ PY T E + ++ R L R
Sbjct: 396 EAANYR------VFSQKSDVWSFGVLLHEVFTYGQCPY--EGMTNHETLQQIMRGYRLPR 447
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
P+ A P E +M +CW +P+ RP F L + + R
Sbjct: 448 PA----ACPAEVYVLMLECWRSSPEERPSFATLREKLHAIHR 485
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 75.8 bits (178), Expect = 9e-13
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 575 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 634
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 635 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 693
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 694 KNVLKISDFGM-SREEADGVYAASGGSRQVPVKWTAPEALNYGR------YSSESDVWSF 746
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 747 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 799
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 800 EPGQRPSFSTIYQELQSIRK 819
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 75.8 bits (178), Expect = 9e-13
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 505 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 564
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 565 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 623
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 624 KNVLKISDFGM-SREEADGVYAASGGSRQVPVKWTAPEALNYGR------YSSESDVWSF 676
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 677 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 729
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 730 EPGQRPSFSTIYQELQSIRK 749
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 75.8 bits (178), Expect = 9e-13
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 517 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 576
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 577 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 635
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 636 KNVLKISDFGM-SREEADGVYAASGGSRQVPVKWTAPEALNYGR------YSSESDVWSF 688
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 689 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 741
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 742 EPGQRPSFSTIYQELQSIRK 761
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 75.8 bits (178), Expect = 9e-13
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 447 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 506
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 507 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 565
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 566 KNVLKISDFGM-SREEADGVYAASGGSRQVPVKWTAPEALNYGR------YSSESDVWSF 618
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 619 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 671
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 672 EPGQRPSFSTIYQELQSIRK 691
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 358 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 417
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 418 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 476
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 477 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 529
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 530 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 573
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 270 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 329
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 330 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 388
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 389 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 441
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 442 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 485
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 575 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 634
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 635 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 693
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 694 KNVLKISDFGM-SREEADGVYAASGGLRQVPVKWTAPEALNYGR------YSSESDVWSF 746
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 747 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 799
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 800 EPGQRPSFSTIYQELQSIRK 819
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 557 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 616
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 617 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 675
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 676 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 728
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 729 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 772
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 562 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 621
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 622 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 680
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 681 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 733
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 734 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 777
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/260 (25%), Positives = 114/260 (43%), Gaps = 20/260 (7%)
Query: 592 VVDRRIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALV 651
V R+R V ++ + T +LK K +++ N+ IG + +P +
Sbjct: 575 VFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYI 634
Query: 652 FDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDS 710
E +G L + +L L ++ D GM YL S H L++RNC+V
Sbjct: 635 VMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-SKCCIHRDLAARNCLVTE 693
Query: 711 RWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSF 768
+ VL+++D+G+ + G+ A R+ + WTAPE + R + DV+SF
Sbjct: 694 KNVLKISDFGM-SREEADGVYAASGGLRQVPVKWTAPEALNYGR------YSSESDVWSF 746
Query: 769 AIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSE 826
I++ E G PY LS E ++K R P P + P +M QCW+
Sbjct: 747 GILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL----CPDAVFRLMEQCWAY 799
Query: 827 APDLRPDFNRLHDVFRQMQR 846
P RP F+ ++ + +++
Sbjct: 800 EPGQRPSFSTIYQELQSIRK 819
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 557 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 616
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 617 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 675
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 676 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 728
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 729 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 772
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 74.9 bits (176), Expect = 2e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 563 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 622
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 623 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 681
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 682 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 734
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 735 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREPQQRHSIKDVH 778
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 73.7 bits (173), Expect = 4e-12
Identities = 67/229 (29%), Positives = 103/229 (44%), Gaps = 30/229 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 206 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 265
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 266 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 324
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 325 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 377
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLH 838
E ID + + L RP A PPE ++MR CW P R +H
Sbjct: 378 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWHGEPQQRHSIKDVH 421
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 72.9 bits (171), Expect = 6e-12
Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 627 LMQNLRQEN-VNPFIGCLCEGRPALVFDECWR-GSLEDVLMADD-IKLDWTFRLSLLSDL 683
+M+NLR + + C E P + E R GSL++ L D K+ T ++ + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLED-PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQV 338
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQG---LPPAQRTPREL 740
GM YL S H L++RN +V + +V D+GL + + +
Sbjct: 339 ASGMAYLE-SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPV 397
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRP 799
WTAPE IR + + DV+SF I++ E+I G+ PY T ++I L +
Sbjct: 398 KWTAPEAIRSNK------FSIKSDVWSFGILLYEIITYGKMPYS--GMTGAQVIQMLAQN 449
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +PS P + ++M +CW+ P RP F L
Sbjct: 450 YRLPQPS----NCPQQFYNIMLECWNAEPKERPTFETL 483
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 72.9 bits (171), Expect = 6e-12
Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 627 LMQNLRQEN-VNPFIGCLCEGRPALVFDECWR-GSLEDVLMADD-IKLDWTFRLSLLSDL 683
+M+NLR + + C E P + E R GSL++ L D K+ T ++ + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLED-PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQV 338
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQG---LPPAQRTPREL 740
GM YL S H L++RN +V + +V D+GL + + +
Sbjct: 339 ASGMAYLE-SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPV 397
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRP 799
WTAPE IR + + DV+SF I++ E+I G+ PY T ++I L +
Sbjct: 398 KWTAPEAIRSNK------FSIKSDVWSFGILLYEIITYGKMPYS--GMTGAQVIQMLAQN 449
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +PS P + ++M +CW+ P RP F L
Sbjct: 450 YRLPQPS----NCPQQFYNIMLECWNAEPKERPTFETL 483
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 14/197 (7%)
Query: 642 CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRL 701
CL + LVF+ G L D L L + D+ +GM YL + + H L
Sbjct: 425 CLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV-IHRDL 483
Query: 702 SSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQ 761
++RNC+V V++V+D+G+ + T + W +PE+ +R +
Sbjct: 484 AARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY------SS 537
Query: 762 SGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVM 820
DV+SF ++M EV G+ PY S + E+++ + L +P + A +M
Sbjct: 538 KSDVWSFGVLMWEVFSEGKIPYENRSNS--EVVEDISTGFRLYKPRL----ASTHVYQIM 591
Query: 821 RQCWSEAPDLRPDFNRL 837
CW E P+ RP F+RL
Sbjct: 592 NHCWKERPEDRPAFSRL 608
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 14/197 (7%)
Query: 642 CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRL 701
CL + LVF+ G L D L L + D+ +GM YL + + H L
Sbjct: 425 CLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV-IHRDL 483
Query: 702 SSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQ 761
++RNC+V V++V+D+G+ + T + W +PE+ +R +
Sbjct: 484 AARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY------SS 537
Query: 762 SGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVM 820
DV+SF ++M EV G+ PY S + E+++ + L +P + A +M
Sbjct: 538 KSDVWSFGVLMWEVFSEGKIPYENRSNS--EVVEDISTGFRLYKPRL----ASTHVYQIM 591
Query: 821 RQCWSEAPDLRPDFNRL 837
CW E P+ RP F+RL
Sbjct: 592 NHCWKERPEDRPAFSRL 608
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 14/197 (7%)
Query: 642 CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRL 701
CL + LVF+ G L D L L + D+ +GM YL + + H L
Sbjct: 425 CLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV-IHRDL 483
Query: 702 SSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQ 761
++RNC+V V++V+D+G+ + T + W +PE+ +R +
Sbjct: 484 AARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY------SS 537
Query: 762 SGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVM 820
DV+SF ++M EV G+ PY S + E+++ + L +P + A +M
Sbjct: 538 KSDVWSFGVLMWEVFSEGKIPYENRSNS--EVVEDISTGFRLYKPRL----ASTHVYQIM 591
Query: 821 RQCWSEAPDLRPDFNRL 837
CW E P+ RP F+RL
Sbjct: 592 NHCWKERPEDRPAFSRL 608
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 14/197 (7%)
Query: 642 CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRL 701
CL + LVF+ G L D L L + D+ +GM YL + + H L
Sbjct: 425 CLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV-IHRDL 483
Query: 702 SSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQ 761
++RNC+V V++V+D+G+ + T + W +PE+ +R +
Sbjct: 484 AARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY------SS 537
Query: 762 SGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVM 820
DV+SF ++M EV G+ PY S + E+++ + L +P + A +M
Sbjct: 538 KSDVWSFGVLMWEVFSEGKIPYENRSNS--EVVEDISTGFRLYKPRL----ASTHVYQIM 591
Query: 821 RQCWSEAPDLRPDFNRL 837
CW E P+ RP F+RL
Sbjct: 592 NHCWKERPEDRPAFSRL 608
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/197 (27%), Positives = 90/197 (45%), Gaps = 14/197 (7%)
Query: 642 CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRL 701
CL + LVF+ G L D L L + D+ +GM YL + + H L
Sbjct: 425 CLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEGMAYLEEACV-IHRDL 483
Query: 702 SSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQ 761
++RNC+V V++V+D+G+ + T + W +PE+ +R +
Sbjct: 484 AARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRY------SS 537
Query: 762 SGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVM 820
DV+SF ++M EV G+ PY S + E+++ + L +P + A +M
Sbjct: 538 KSDVWSFGVLMWEVFSEGKIPYENRSNS--EVVEDISTGFRLYKPRL----ASTHVYQIM 591
Query: 821 RQCWSEAPDLRPDFNRL 837
CW E P+ RP F+RL
Sbjct: 592 NHCWKERPEDRPAFSRL 608
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 72.9 bits (171), Expect = 6e-12
Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 627 LMQNLRQEN-VNPFIGCLCEGRPALVFDECWR-GSLEDVLMADD-IKLDWTFRLSLLSDL 683
+M+NLR + + C E P + E R GSL++ L D K+ T ++ + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLED-PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQV 338
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQG---LPPAQRTPREL 740
GM YL S H L++RN +V + +V D+GL + + +
Sbjct: 339 ASGMAYLE-SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPV 397
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRP 799
WTAPE IR + + DV+SF I++ E+I G+ PY T ++I L +
Sbjct: 398 KWTAPEAIRSNK------FSIKSDVWSFGILLYEIITYGKMPYS--GMTGAQVIQMLAQN 449
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +PS P + ++M +CW+ P RP F L
Sbjct: 450 YRLPQPS----NCPQQFYNIMLECWNAEPKERPTFETL 483
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 72.9 bits (171), Expect = 6e-12
Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 627 LMQNLRQEN-VNPFIGCLCEGRPALVFDECWR-GSLEDVLMADD-IKLDWTFRLSLLSDL 683
+M+NLR + + C E P + E R GSL++ L D K+ T ++ + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLED-PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQV 338
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQG---LPPAQRTPREL 740
GM YL S H L++RN +V + +V D+GL + + +
Sbjct: 339 ASGMAYLE-SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPV 397
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRP 799
WTAPE IR + + DV+SF I++ E+I G+ PY T ++I L +
Sbjct: 398 KWTAPEAIRSNK------FSIKSDVWSFGILLYEIITYGKMPYS--GMTGAQVIQMLAQN 449
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +PS P + ++M +CW+ P RP F L
Sbjct: 450 YRLPQPS----NCPQQFYNIMLECWNAEPKERPTFETL 483
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 72.9 bits (171), Expect = 6e-12
Identities = 62/218 (28%), Positives = 100/218 (45%), Gaps = 21/218 (9%)
Query: 627 LMQNLRQEN-VNPFIGCLCEGRPALVFDECWR-GSLEDVLMADD-IKLDWTFRLSLLSDL 683
+M+NLR + + C E P + E R GSL++ L D K+ T ++ + + +
Sbjct: 280 IMKNLRHPKLIQLYAVCTLED-PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQV 338
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQG---LPPAQRTPREL 740
GM YL S H L++RN +V + +V D+GL + + +
Sbjct: 339 ASGMAYLE-SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPV 397
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRP 799
WTAPE IR + + DV+SF I++ E+I G+ PY T ++I L +
Sbjct: 398 KWTAPEAIRSNK------FSIKSDVWSFGILLYEIITYGKMPYS--GMTGAQVIQMLAQN 449
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +PS P + ++M +CW+ P RP F L
Sbjct: 450 YRLPQPS----NCPQQFYNIMLECWNAEPKERPTFETL 483
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 71/242 (29%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG 658
Y G V +++++ T + T V+ MQ+ EN+ +G + +V + +G
Sbjct: 254 YLGQKVAVKNIKCDVTAQAFLDETAVMTKMQH---ENLVRLLGVILHQGLYIVMEHVSKG 310
Query: 659 SLEDVLMADDIKLDWTFRLSLLS-DLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
+L + L L T +L S + +GM YL L H L++RN +V V +V+
Sbjct: 311 NLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL-VHRDLAARNILVSEDLVAKVS 369
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
D+GL R +GL + R P + WTAPE ++ + T DV+SF +++ EV
Sbjct: 370 DFGLAKAER-KGL-DSSRLP--VKWTAPEALKHGK------FTSKSDVWSFGVLLWEVFS 419
Query: 778 RGE-PYCMLSFTP-EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY +S E ++K R P P G P V +M CW P RP F
Sbjct: 420 YGRAPYPKMSLKEVSEAVEKGYRMEP---PE---GCPGPVHV-LMSSCWEAEPARRPPFR 472
Query: 836 RL 837
+L
Sbjct: 473 KL 474
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 71/242 (29%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG 658
Y G V +++++ T + T V+ MQ+ EN+ +G + +V + +G
Sbjct: 254 YLGQKVAVKNIKCDVTAQAFLDETAVMTKMQH---ENLVRLLGVILHQGLYIVMEHVSKG 310
Query: 659 SLEDVLMADDIKLDWTFRLSLLS-DLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
+L + L L T +L S + +GM YL L H L++RN +V V +V+
Sbjct: 311 NLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL-VHRDLAARNILVSEDLVAKVS 369
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
D+GL R +GL + R P + WTAPE ++ + T DV+SF +++ EV
Sbjct: 370 DFGLAKAER-KGL-DSSRLP--VKWTAPEALKHGK------FTSKSDVWSFGVLLWEVFS 419
Query: 778 RGE-PYCMLSFTP-EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY +S E ++K R P P G P V +M CW P RP F
Sbjct: 420 YGRAPYPKMSLKEVSEAVEKGYRMEP---PE---GCPGPVHV-LMSSCWEAEPARRPPFR 472
Query: 836 RL 837
+L
Sbjct: 473 KL 474
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 71/242 (29%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG 658
Y G V +++++ T + T V+ MQ+ EN+ +G + +V + +G
Sbjct: 254 YLGQKVAVKNIKCDVTAQAFLDETAVMTKMQH---ENLVRLLGVILHQGLYIVMEHVSKG 310
Query: 659 SLEDVLMADDIKLDWTFRLSLLS-DLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
+L + L L T +L S + +GM YL L H L++RN +V V +V+
Sbjct: 311 NLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL-VHRDLAARNILVSEDLVAKVS 369
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
D+GL R +GL + R P + WTAPE ++ + T DV+SF +++ EV
Sbjct: 370 DFGLAKAER-KGL-DSSRLP--VKWTAPEALKHGK------FTSKSDVWSFGVLLWEVFS 419
Query: 778 RGE-PYCMLSFTP-EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY +S E ++K R P P G P V +M CW P RP F
Sbjct: 420 YGRAPYPKMSLKEVSEAVEKGYRMEP---PE---GCPGPVHV-LMSSCWEAEPARRPPFR 472
Query: 836 RL 837
+L
Sbjct: 473 KL 474
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 71/242 (29%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG 658
Y G V +++++ T + T V+ MQ+ EN+ +G + +V + +G
Sbjct: 254 YLGQKVAVKNIKCDVTAQAFLDETAVMTKMQH---ENLVRLLGVILHQGLYIVMEHVSKG 310
Query: 659 SLEDVLMADDIKLDWTFRLSLLS-DLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
+L + L L T +L S + +GM YL L H L++RN +V V +V+
Sbjct: 311 NLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL-VHRDLAARNILVSEDLVAKVS 369
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
D+GL R +GL + R P + WTAPE ++ + T DV+SF +++ EV
Sbjct: 370 DFGLAKAER-KGL-DSSRLP--VKWTAPEALKHGK------FTSKSDVWSFGVLLWEVFS 419
Query: 778 RGE-PYCMLSFTP-EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY +S E ++K R P P G P V +M CW P RP F
Sbjct: 420 YGRAPYPKMSLKEVSEAVEKGYRMEP---PE---GCPGPVHV-LMSSCWEAEPARRPPFR 472
Query: 836 RL 837
+L
Sbjct: 473 KL 474
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 72.1 bits (169), Expect = 1e-11
Identities = 71/242 (29%), Positives = 111/242 (45%), Gaps = 24/242 (9%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG 658
Y G V +++++ T + T V+ MQ+ EN+ +G + +V + +G
Sbjct: 254 YLGQKVAVKNIKCDVTAQAFLDETAVMTKMQH---ENLVRLLGVILHQGLYIVMEHVSKG 310
Query: 659 SLEDVLMADDIKLDWTFRLSLLS-DLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
+L + L L T +L S + +GM YL L H L++RN +V V +V+
Sbjct: 311 NLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLESKKL-VHRDLAARNILVSEDLVAKVS 369
Query: 718 DYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
D+GL R +GL + R P + WTAPE ++ + T DV+SF +++ EV
Sbjct: 370 DFGLAKAER-KGL-DSSRLP--VKWTAPEALKHGK------FTSKSDVWSFGVLLWEVFS 419
Query: 778 RGE-PYCMLSFTP-EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY +S E ++K R P P G P V +M CW P RP F
Sbjct: 420 YGRAPYPKMSLKEVSEAVEKGYRMEP---PE---GCPGPVHV-LMSSCWEAEPARRPPFR 472
Query: 836 RL 837
+L
Sbjct: 473 KL 474
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 71.7 bits (168), Expect = 1e-11
Identities = 65/219 (29%), Positives = 100/219 (45%), Gaps = 30/219 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMA-----------DDIK---L 671
L+ L+ +++ F G EGRP L VF+ G L L + +D+ L
Sbjct: 386 LLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPL 445
Query: 672 DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGL 730
L++ S + GM YL G H L++RNC+V V+++ D+G+ ++ T
Sbjct: 446 GLGQLLAVASQVAAGMVYLAGLHF-VHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYY 504
Query: 731 PPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTP 789
RT + W PE I + T DV+SF +++ E+ G +P+ LS T
Sbjct: 505 RVGGRTMLPIRWMPPESILYRK------FTTESDVWSFGVVLWEIFTYGKQPWYQLSNT- 557
Query: 790 EEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAP 828
E ID + + L RP A PPE ++MR CW P
Sbjct: 558 -EAIDCITQGRELERPR----ACPPEVYAIMRGCWQREP 591
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 71.7 bits (168), Expect = 1e-11
Identities = 66/218 (30%), Positives = 101/218 (46%), Gaps = 21/218 (9%)
Query: 623 DVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSD 682
D +M ++ EN+ +G + + +V + +G+L + L L T +L S
Sbjct: 233 DETAVMTKMQHENLVRLLGVILDQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSL 292
Query: 683 LVK-GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELL 741
V+ GM YL L H L++RN +V V +V+D+GL R +GL + R P +
Sbjct: 293 HVREGMEYLESKKL-VHRDLAARNILVSEELVAKVSDFGLAKAER-KGL-DSSRLP--VK 347
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTP-EEIIDKLCRP 799
WTAPE ++ + T DV+SF +++ EV G PY +S E ++K R
Sbjct: 348 WTAPEALKHGK------FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKRYRM 401
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P P G P V +M CW P RP F +L
Sbjct: 402 EP---PE---GCPGPVHV-LMSSCWEAEPARRPPFRKL 432
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 291 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 350
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 351 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 409
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 410 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 461
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 462 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 493
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 291 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 350
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 351 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 409
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 410 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 461
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 462 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 493
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 292 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 351
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 352 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 410
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 411 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 462
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 463 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 494
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 291 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 350
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 351 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 409
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 410 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 461
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 462 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 493
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 278 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 337
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 338 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 396
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 397 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 448
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 449 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 480
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 298 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 357
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 358 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 416
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 417 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 468
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 469 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 500
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 278 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 337
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 338 GMAFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 396
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 397 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNPEVIQNLERGYRMVR 448
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 449 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 480
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 70.1 bits (164), Expect = 5e-11
Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M L + G + +P + E RG L + L LS+ D+ +
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCE 475
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM YL + H L++RNC+V V++V+D+G+ + + W P
Sbjct: 476 GMEYLERNSF-IHRDLAARNCLVSEAGVVKVSDFGMARYFLDDQYTSSSGAKFPVKWCPP 534
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E+ +R + DV+SF ++M EV G P+ +T E++ + R L +
Sbjct: 535 EVFNYSR------FSSKSDVWSFGVLMWEVFTEGRMPF--EKYTNYEVVTMVTRGHRLYQ 586
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A VM +CW E P+ RP F L
Sbjct: 587 PKL----ASNYVYEVMLRCWQEKPEGRPSFEDL 615
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 70.1 bits (164), Expect = 5e-11
Identities = 55/185 (29%), Positives = 79/185 (42%), Gaps = 15/185 (8%)
Query: 658 GSLEDVLMADD-IKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
GSL D L IKL L + + + +GM ++ H L + N +V ++
Sbjct: 352 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY-IHRDLRAANILVSDTLSCKI 410
Query: 717 TDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI 776
D+GL L + + WTAPE I T DV+SF I++ E++
Sbjct: 411 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT------FTIKSDVWSFGILLTEIV 464
Query: 777 VRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY T E+I L R ++RP P E +MR CW E P+ RP F+
Sbjct: 465 THGRIPYP--GMTNPEVIQNLERGYRMVRPD----NCPEELYQLMRLCWKERPEDRPTFD 518
Query: 836 RLHDV 840
L V
Sbjct: 519 YLRSV 523
>AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 526
Score = 70.1 bits (164), Expect = 5e-11
Identities = 55/185 (29%), Positives = 79/185 (42%), Gaps = 15/185 (8%)
Query: 658 GSLEDVLMADD-IKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRV 716
GSL D L IKL L + + + +GM ++ H L + N +V ++
Sbjct: 339 GSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNY-IHRDLRAANILVSDTLSCKI 397
Query: 717 TDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI 776
D+GL L + + WTAPE I T DV+SF I++ E++
Sbjct: 398 ADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGT------FTIKSDVWSFGILLTEIV 451
Query: 777 VRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFN 835
G PY T E+I L R ++RP P E +MR CW E P+ RP F+
Sbjct: 452 THGRIPYP--GMTNPEVIQNLERGYRMVRPD----NCPEELYQLMRLCWKERPEDRPTFD 505
Query: 836 RLHDV 840
L V
Sbjct: 506 YLRSV 510
>AC069008-1|AAS07467.1| 105|Homo sapiens unknown protein.
Length = 105
Score = 70.1 bits (164), Expect = 5e-11
Identities = 33/83 (39%), Positives = 49/83 (59%)
Query: 910 EEFEEVSIYFSDIVGFTALAARSTAVQVVDLLNDLYTTFDAAIEQYRVYKVETIGDAYMV 969
+ + VSI F+DIVGFT LA++ TA ++V LLN+L+ FD + +++ +GD Y
Sbjct: 19 QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC 78
Query: 970 VGGLPQRTRDHAESVATMALHLL 992
V GL Q DHA M L ++
Sbjct: 79 VSGLTQPKTDHAHCCVEMGLDMI 101
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 69.7 bits (163), Expect = 6e-11
Identities = 58/216 (26%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADD-IKLDWTFRLSLLSDLVK 685
LM+ L+ + + + + ++ + GSL D L IKL L + + + +
Sbjct: 294 LMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAE 353
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM ++ H L + N +V ++ D+GL L + + WTAP
Sbjct: 354 GMVFIEERNY-IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 412
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E I T DV+SF I++ E++ G PY T E+I L R ++R
Sbjct: 413 EAINYGT------FTIKSDVWSFGILLTEIVTHGRIPYP--GMTNLEVIQNLERGYRMVR 464
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDV 840
P P E +MR CW E P+ RP F+ L V
Sbjct: 465 PD----NCPEELYQLMRLCWKERPEDRPTFDYLRSV 496
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 69.3 bits (162), Expect = 8e-11
Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 25/252 (9%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
+V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 649 SVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLD 708
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 709 SFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGL 767
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T R + WT+PE I + T + DV+S+ I++ EV+
Sbjct: 768 SRV--LEDDPEAAYTTRGGKIPIRWTSPEAIAYRK------FTSASDVWSYGIVLWEVMS 819
Query: 778 RGE-PYCMLSFTPE-EIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
GE PY +S + +D+ R PPP+ P +M CW + + RP F
Sbjct: 820 YGERPYWEMSNQDVIKAVDEGYRLPPPM--------DCPAALYQLMLDCWQKDRNNRPKF 871
Query: 835 NRLHDVFRQMQR 846
++ + ++ R
Sbjct: 872 EQIVSILDKLIR 883
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 69.3 bits (162), Expect = 8e-11
Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M L + G + +P + E RG L + L LS+ D+ +
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCE 475
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM YL + H L++RNC+V V++V+D+G+ + + W P
Sbjct: 476 GMEYLERNSF-IHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPP 534
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E+ +R + DV+SF ++M EV G P+ +T E++ + R L +
Sbjct: 535 EVFNYSR------FSSKSDVWSFGVLMWEVFTEGRMPF--EKYTNYEVVTMVTRGHRLYQ 586
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A VM +CW E P+ RP F L
Sbjct: 587 PKL----ASNYVYEVMLRCWQEKPEGRPSFEDL 615
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 69.3 bits (162), Expect = 8e-11
Identities = 55/213 (25%), Positives = 90/213 (42%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M L + G + +P + E RG L + L LS+ D+ +
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCE 475
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM YL + H L++RNC+V V++V+D+G+ + + W P
Sbjct: 476 GMEYLERNSF-IHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPP 534
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E+ +R + DV+SF ++M EV G P+ +T E++ + R L +
Sbjct: 535 EVFNYSR------FSSKSDVWSFGVLMWEVFTEGRMPF--EKYTNYEVVTMVTRGHRLYQ 586
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A VM +CW E P+ RP F L
Sbjct: 587 PKL----ASNYVYEVMLRCWQEKPEGRPSFEDL 615
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 69.3 bits (162), Expect = 8e-11
Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 25/252 (9%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
+V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 649 SVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLD 708
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 709 SFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGL 767
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T R + WT+PE I + T + DV+S+ I++ EV+
Sbjct: 768 SRV--LEDDPEAAYTTRGGKIPIRWTSPEAIAYRK------FTSASDVWSYGIVLWEVMS 819
Query: 778 RGE-PYCMLSFTPE-EIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
GE PY +S + +D+ R PPP+ P +M CW + + RP F
Sbjct: 820 YGERPYWEMSNQDVIKAVDEGYRLPPPM--------DCPAALYQLMLDCWQKDRNNRPKF 871
Query: 835 NRLHDVFRQMQR 846
++ + ++ R
Sbjct: 872 EQIVSILDKLIR 883
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 69.3 bits (162), Expect = 8e-11
Identities = 68/247 (27%), Positives = 116/247 (46%), Gaps = 29/247 (11%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQ 773
+V+D+GL TQ + P + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGLTKEASTQD---TGKLP--VKWTAPEALREKK-----FSTKS-DVWSFGILLW 376
Query: 774 EVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRP 832
E+ G PY + ++++ ++ + + P PP VM+ CW +RP
Sbjct: 377 EIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMRP 430
Query: 833 DFNRLHD 839
F +L +
Sbjct: 431 SFLQLRE 437
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 69.3 bits (162), Expect = 8e-11
Identities = 64/252 (25%), Positives = 115/252 (45%), Gaps = 25/252 (9%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
+V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 649 SVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLD 708
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 709 SFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGL 767
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T R + WT+PE I + T + DV+S+ I++ EV+
Sbjct: 768 SRV--LEDDPEAAYTTRGGKIPIRWTSPEAIAYRK------FTSASDVWSYGIVLWEVMS 819
Query: 778 RGE-PYCMLSFTPE-EIIDKLCR-PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
GE PY +S + +D+ R PPP+ P +M CW + + RP F
Sbjct: 820 YGERPYWEMSNQDVIKAVDEGYRLPPPM--------DCPAALYQLMLDCWQKDRNNRPKF 871
Query: 835 NRLHDVFRQMQR 846
++ + ++ R
Sbjct: 872 EQIVSILDKLIR 883
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosine
kinase protein.
Length = 1124
Score = 68.9 bits (161), Expect = 1e-10
Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 22/251 (8%)
Query: 601 GDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLC-EGRPAL--VFDECWR 657
G V ++ LQ +G + +R + +++ L + + + G GRP L V +
Sbjct: 849 GALVAVKQLQHSGP-DQQRDFQREIQILKALHSDFIVKYRGVSYGPGRPELRLVMEYLPS 907
Query: 658 GSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVT 717
G L D L +LD + L S + KGM YL GS H L++RN +V+S +++
Sbjct: 908 GCLRDFLQRHRARLDASRLLLYSSQICKGMEYL-GSRRCVHRDLAARNILVESEAHVKIA 966
Query: 718 DYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEV 775
D+GL L R P + + W APE + + + ++ DV+SF +++ E+
Sbjct: 967 DFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDN------IFSRQSDVWSFGVVLYEL 1020
Query: 776 IVRGEPYCMLS------FTPEEIIDKLCRPPPLIRPSVSMGA---APPEAVSVMRQCWSE 826
+ C S E + LCR L+ + A P E +M+ CW+
Sbjct: 1021 FTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAP 1080
Query: 827 APDLRPDFNRL 837
+P RP F+ L
Sbjct: 1081 SPQDRPSFSAL 1091
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 68.9 bits (161), Expect = 1e-10
Identities = 51/159 (32%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 627 LMQNLRQENVNPFIG-CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
LM LR N+ F+G C+ +G+ + + G+LE +L + + L W RL L D+ +
Sbjct: 103 LMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPE-PLSWPVRLHLALDIAR 161
Query: 686 GMRYLHGSPLRAHGRLSSRNCVV---DSRWVLRVTDYGLP---ALHRTQGLPPAQRTPRE 739
G+RYLH + H L+S+NC+V D + V D+GL ++R
Sbjct: 162 GLRYLHSKGV-FHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGS 220
Query: 740 LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
W APE++R G L + DVF+F I++ E+I R
Sbjct: 221 PYWMAPEVLR------GELYDEKADVFAFGIVLCELIAR 253
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 68.9 bits (161), Expect = 1e-10
Identities = 68/248 (27%), Positives = 117/248 (47%), Gaps = 30/248 (12%)
Query: 599 YKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPAL--VFDECW 656
Y+G+ V ++ ++ T + V M LR N+ +G + E + L V +
Sbjct: 214 YRGNKVAVKCIKNDATAQAFLAEASV---MTQLRHSNLVQLLGVIVEEKGGLYIVTEYMA 270
Query: 657 RGSLEDVLMADDIKL---DWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWV 713
+GSL D L + + D + SL D+ + M YL G+ H L++RN +V V
Sbjct: 271 KGSLVDYLRSRGRSVLGGDCLLKFSL--DVCEAMEYLEGNNF-VHRDLAARNVLVSEDNV 327
Query: 714 LRVTDYGLPALHRTQGLPPAQRTPR-ELLWTAPELIREAREGGGWLATQSGDVFSFAIIM 772
+V+D+GL T+ Q T + + WTAPE +RE + +T+S DV+SF I++
Sbjct: 328 AKVSDFGL-----TKEASSTQDTGKLPVKWTAPEALREKK-----FSTKS-DVWSFGILL 376
Query: 773 QEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLR 831
E+ G PY + ++++ ++ + + P PP VM+ CW +R
Sbjct: 377 WEIYSFGRVPYPRIPL--KDVVPRVEKGYKMDAPD----GCPPAVYEVMKNCWHLDAAMR 430
Query: 832 PDFNRLHD 839
P F +L +
Sbjct: 431 PSFLQLRE 438
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 68.9 bits (161), Expect = 1e-10
Identities = 51/159 (32%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 627 LMQNLRQENVNPFIG-CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
LM LR N+ F+G C+ +G+ + + G+LE +L + + L W RL L D+ +
Sbjct: 103 LMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPE-PLSWPVRLHLALDIAR 161
Query: 686 GMRYLHGSPLRAHGRLSSRNCVV---DSRWVLRVTDYGLP---ALHRTQGLPPAQRTPRE 739
G+RYLH + H L+S+NC+V D + V D+GL ++R
Sbjct: 162 GLRYLHSKGV-FHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGS 220
Query: 740 LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
W APE++R G L + DVF+F I++ E+I R
Sbjct: 221 PYWMAPEVLR------GELYDEKADVFAFGIVLCELIAR 253
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 68.9 bits (161), Expect = 1e-10
Identities = 51/159 (32%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 627 LMQNLRQENVNPFIG-CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
LM LR N+ F+G C+ +G+ + + G+LE +L + + L W RL L D+ +
Sbjct: 103 LMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPE-PLSWPVRLHLALDIAR 161
Query: 686 GMRYLHGSPLRAHGRLSSRNCVV---DSRWVLRVTDYGLP---ALHRTQGLPPAQRTPRE 739
G+RYLH + H L+S+NC+V D + V D+GL ++R
Sbjct: 162 GLRYLHSKGV-FHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGS 220
Query: 740 LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
W APE++R G L + DVF+F I++ E+I R
Sbjct: 221 PYWMAPEVLR------GELYDEKADVFAFGIVLCELIAR 253
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 68.9 bits (161), Expect = 1e-10
Identities = 51/159 (32%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 627 LMQNLRQENVNPFIG-CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
LM LR N+ F+G C+ +G+ + + G+LE +L + + L W RL L D+ +
Sbjct: 103 LMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPE-PLSWPVRLHLALDIAR 161
Query: 686 GMRYLHGSPLRAHGRLSSRNCVV---DSRWVLRVTDYGLP---ALHRTQGLPPAQRTPRE 739
G+RYLH + H L+S+NC+V D + V D+GL ++R
Sbjct: 162 GLRYLHSKGV-FHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGS 220
Query: 740 LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
W APE++R G L + DVF+F I++ E+I R
Sbjct: 221 PYWMAPEVLR------GELYDEKADVFAFGIVLCELIAR 253
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
kinase protein.
Length = 1037
Score = 68.5 bits (160), Expect = 1e-10
Identities = 64/249 (25%), Positives = 113/249 (45%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 704 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 763
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 764 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGLS 822
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ + P A T R + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 823 RV--LEDDPEAAYTTRGGKIPIRWTAPEAIAFRK------FTSASDVWSYGIVMWEVVSY 874
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I + L P P +M CW + + RP F+ +
Sbjct: 875 GERPY--WEMTNQDVIKAVEEGYRLPSPM----DCPAALYQLMLDCWQKERNSRPKFDEI 928
Query: 838 HDVFRQMQR 846
++ ++ R
Sbjct: 929 VNMLDKLIR 937
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 68.5 bits (160), Expect = 1e-10
Identities = 64/249 (25%), Positives = 113/249 (45%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 658 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 717
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 718 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGLS 776
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ + P A T R + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 777 RV--LEDDPEAAYTTRGGKIPIRWTAPEAIAFRK------FTSASDVWSYGIVMWEVVSY 828
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I + L P P +M CW + + RP F+ +
Sbjct: 829 GERPY--WEMTNQDVIKAVEEGYRLPSPM----DCPAALYQLMLDCWQKERNSRPKFDEI 882
Query: 838 HDVFRQMQR 846
++ ++ R
Sbjct: 883 VNMLDKLIR 891
>AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes
variant 2 protein.
Length = 681
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/174 (29%), Positives = 83/174 (47%), Gaps = 19/174 (10%)
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
L + D GM YL S H L++RNC+V + VL+++D+G+ + G+ A
Sbjct: 520 LQTVGDAAAGMEYLE-SKCCIHRDLAARNCLVTEKNVLKISDFGM-SREEADGVYAASGG 577
Query: 737 PRE--LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLS-FTPEEI 792
R+ + WTAPE + R + DV+SF I++ E G PY LS E
Sbjct: 578 LRQVPVKWTAPEALNYGR------YSSESDVWSFGILLWETFSLGASPYPNLSNQQTREF 631
Query: 793 IDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
++K RPP P + P +M QCW+ P RP F+ ++ + +++
Sbjct: 632 VEKGGRPP---CPEL----CPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRK 678
>AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-1
protein.
Length = 244
Score = 68.5 bits (160), Expect = 1e-10
Identities = 51/159 (32%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 627 LMQNLRQENVNPFIG-CLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
LM LR N+ F+G C+ +G+ + + G+LE +L + + L W RL L D+ +
Sbjct: 19 LMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEXLLSSPE-PLSWPVRLHLALDIAR 77
Query: 686 GMRYLHGSPLRAHGRLSSRNCVV---DSRWVLRVTDYGLP---ALHRTQGLPPAQRTPRE 739
G+RYLH + H L+S+NC+V D + V D+GL ++R
Sbjct: 78 GLRYLHSKGV-FHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGS 136
Query: 740 LLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
W APE++R G L + DVF+F I++ E+I R
Sbjct: 137 PYWMAPEVLR------GELYDEKADVFAFGIVLCELIAR 169
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 68.5 bits (160), Expect = 1e-10
Identities = 64/249 (25%), Positives = 113/249 (45%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 718 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 777
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +++S V +V+D+GL
Sbjct: 778 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFGLS 836
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ + P A T R + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 837 RV--LEDDPEAAYTTRGGKIPIRWTAPEAIAFRK------FTSASDVWSYGIVMWEVVSY 888
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I + L P P +M CW + + RP F+ +
Sbjct: 889 GERPY--WEMTNQDVIKAVEEGYRLPSPM----DCPAALYQLMLDCWQKERNSRPKFDEI 942
Query: 838 HDVFRQMQR 846
++ ++ R
Sbjct: 943 VNMLDKLIR 951
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 446 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 505
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 506 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 564
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 565 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 616
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 617 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 645
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 68.1 bits (159), Expect = 2e-10
Identities = 53/213 (24%), Positives = 94/213 (44%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECW-RGSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NL E + G + RP + E G L + L + L + D+ +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
M YL H L++RNC+V+ + V++V+D+GL + + + W+ P
Sbjct: 508 AMEYLESKQF-LHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 566
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E++ ++ + D+++F ++M E+ G+ PY FT E + + + L R
Sbjct: 567 EVLMYSK------FSSKSDIWAFGVLMWEIYSLGKMPY--ERFTNSETAEHIAQGLRLYR 618
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + A + ++M CW E D RP F L
Sbjct: 619 PHL----ASEKVYTIMYSCWHEKADERPTFKIL 647
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 666
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 667 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 725
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 726 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 777
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 778 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 832
>AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 666
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 667 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 725
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 726 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 777
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 778 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 832
>AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 666
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 667 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 725
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 726 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 777
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 778 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 832
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 607 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 666
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 667 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 725
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 726 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 777
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 778 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 832
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine
kinase receptor type 2 protein.
Length = 822
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/239 (25%), Positives = 105/239 (43%), Gaps = 28/239 (11%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSL---------EDVLMADD---IKLDW 673
L+ NL+ E++ F G EG P + VF+ G L + VLMA+ +L
Sbjct: 591 LLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQ 650
Query: 674 TFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPP 732
+ L + + GM YL S H L++RNC+V ++++ D+G+ ++ T
Sbjct: 651 SQMLHIAQQIAAGMVYL-ASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRV 709
Query: 733 AQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEE 791
T + W PE I + T DV+S +++ E+ G +P+ LS E
Sbjct: 710 GGHTMLPIRWMPPESIMYRK------FTTESDVWSLGVVLWEIFTYGKQPWYQLS--NNE 761
Query: 792 IIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKI 850
+I+ + + L RP P E +M CW P +R + +H + + + + +
Sbjct: 762 VIECITQGRVLQRPRT----CPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPV 816
>U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein.
Length = 1124
Score = 66.9 bits (156), Expect = 4e-10
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 18/199 (9%)
Query: 650 LVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVD 709
LV + G L D L +LD + L S + KGM YL GS H L++RN +V+
Sbjct: 900 LVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYL-GSRRCVHRDLAARNILVE 958
Query: 710 SRWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFS 767
S +++ D+GL L R P + + W APE + + + ++ DV+S
Sbjct: 959 SEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDN------IFSRQSDVWS 1012
Query: 768 FAIIMQEVIVRGEPYCMLS------FTPEEIIDKLCRPPPLIRPSVSMGA---APPEAVS 818
F +++ E+ + C S E + LCR L+ + A P E
Sbjct: 1013 FGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHE 1072
Query: 819 VMRQCWSEAPDLRPDFNRL 837
+M+ CW+ +P RP F+ L
Sbjct: 1073 LMKLCWAPSPQDRPSFSAL 1091
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 66.9 bits (156), Expect = 4e-10
Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 31/242 (12%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMADD----IKLDWTFR----- 676
L+ NL+ E++ F G +G P + VF+ G L L A I +D R
Sbjct: 591 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPNAMILVDGQPRQAKGE 650
Query: 677 ------LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQG 729
L + S + GM YL S H L++RNC+V + ++++ D+G+ ++ T
Sbjct: 651 LGLSQMLHIASQIASGMVYL-ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY 709
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFT 788
T + W PE I + T DV+SF +I+ E+ G +P+ LS T
Sbjct: 710 YRVGGHTMLPIRWMPPESIMYRK------FTTESDVWSFGVILWEIFTYGKQPWFQLSNT 763
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR 848
E+I+ + + L RP V P E VM CW P R + ++ + + +
Sbjct: 764 --EVIECITQGRVLERPRV----CPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKAT 817
Query: 849 KI 850
I
Sbjct: 818 PI 819
>AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a protein
tyrosine kinase, leukocyte) protein.
Length = 1124
Score = 66.9 bits (156), Expect = 4e-10
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 18/199 (9%)
Query: 650 LVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVD 709
LV + G L D L +LD + L S + KGM YL GS H L++RN +V+
Sbjct: 900 LVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYL-GSRRCVHRDLAARNILVE 958
Query: 710 SRWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFS 767
S +++ D+GL L R P + + W APE + + + ++ DV+S
Sbjct: 959 SEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDN------IFSRQSDVWS 1012
Query: 768 FAIIMQEVIVRGEPYCMLS------FTPEEIIDKLCRPPPLIRPSVSMGA---APPEAVS 818
F +++ E+ + C S E + LCR L+ + A P E
Sbjct: 1013 FGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHE 1072
Query: 819 VMRQCWSEAPDLRPDFNRL 837
+M+ CW+ +P RP F+ L
Sbjct: 1073 LMKLCWAPSPQDRPSFSAL 1091
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 66.9 bits (156), Expect = 4e-10
Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 31/242 (12%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMADD----IKLDWTFR----- 676
L+ NL+ E++ F G +G P + VF+ G L L A I +D R
Sbjct: 84 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGE 143
Query: 677 ------LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQG 729
L + S + GM YL S H L++RNC+V + ++++ D+G+ ++ T
Sbjct: 144 LGLSQMLHIASQIASGMVYL-ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY 202
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFT 788
T + W PE I + T DV+SF +I+ E+ G +P+ LS T
Sbjct: 203 YRVGGHTMLPIRWMPPESIMYRK------FTTESDVWSFGVILWEIFTYGKQPWFQLSNT 256
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR 848
E+I+ + + L RP V P E VM CW P R + ++ + + +
Sbjct: 257 --EVIECITQGRVLERPRV----CPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKAT 310
Query: 849 KI 850
I
Sbjct: 311 PI 312
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 66.9 bits (156), Expect = 4e-10
Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 31/242 (12%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPAL-VFDECWRGSLEDVLMADD----IKLDWTFR----- 676
L+ NL+ E++ F G +G P + VF+ G L L A I +D R
Sbjct: 174 LLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGE 233
Query: 677 ------LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQG 729
L + S + GM YL S H L++RNC+V + ++++ D+G+ ++ T
Sbjct: 234 LGLSQMLHIASQIASGMVYL-ASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY 292
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFT 788
T + W PE I + T DV+SF +I+ E+ G +P+ LS T
Sbjct: 293 YRVGGHTMLPIRWMPPESIMYRK------FTTESDVWSFGVILWEIFTYGKQPWFQLSNT 346
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR 848
E+I+ + + L RP V P E VM CW P R + ++ + + +
Sbjct: 347 --EVIECITQGRVLERPRV----CPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKAT 400
Query: 849 KI 850
I
Sbjct: 401 PI 402
>AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein.
Length = 1124
Score = 66.9 bits (156), Expect = 4e-10
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 18/199 (9%)
Query: 650 LVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVD 709
LV + G L D L +LD + L S + KGM YL GS H L++RN +V+
Sbjct: 900 LVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKGMEYL-GSRRCVHRDLAARNILVE 958
Query: 710 SRWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREAREGGGWLATQSGDVFS 767
S +++ D+GL L R P + + W APE + + + ++ DV+S
Sbjct: 959 SEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDN------IFSRQSDVWS 1012
Query: 768 FAIIMQEVIVRGEPYCMLS------FTPEEIIDKLCRPPPLIRPSVSMGA---APPEAVS 818
F +++ E+ + C S E + LCR L+ + A P E
Sbjct: 1013 FGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCRLLELLEEGQRLPAPPACPAEVHE 1072
Query: 819 VMRQCWSEAPDLRPDFNRL 837
+M+ CW+ +P RP F+ L
Sbjct: 1073 LMKLCWAPSPQDRPSFSAL 1091
>X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein.
Length = 1400
Score = 66.5 bits (155), Expect = 6e-10
Identities = 60/217 (27%), Positives = 92/217 (42%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIGCLC--EGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
LLM+ L NV IG + EG P ++ G L + + +S +
Sbjct: 1133 LLMRGLNHPNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQV 1192
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL--PALHRTQGLPPAQRTPR-EL 740
+GM YL H L++RNC++D + ++V D+GL L R R R +
Sbjct: 1193 ARGMEYLAEQKF-VHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPV 1251
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ R T DV+SF +++ E++ RG P P ++ L +
Sbjct: 1252 KWMALESLQTYR------FTTKSDVWSFGVLLWELLTRGAP-PYRHIDPFDLTHFLAQGR 1304
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L +P P VM+QCW P +RP F L
Sbjct: 1305 RLPQPEY----CPDSLYQVMQQCWEADPAVRPTFRVL 1337
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 710
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 711 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 769
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 770 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 823
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 824 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 873
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 874 FGQIVNTLDKMIR 886
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 634 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 693
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 694 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 752
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 753 RFLEDDTSDPTYTSALGGKFPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 806
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 807 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 856
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 857 FGQIVNTLDKMIR 869
>BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ras 2
protein.
Length = 829
Score = 66.5 bits (155), Expect = 6e-10
Identities = 72/267 (26%), Positives = 124/267 (46%), Gaps = 24/267 (8%)
Query: 598 RYKGD-AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDEC 655
R+ G+ A+ L ++ +LK +V+ Q R ENV F+G C+ A++ C
Sbjct: 563 RWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT-RHENVVLFMGACMSPPHLAIITSLC 621
Query: 656 WRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLR 715
+L V+ I LD + ++VKGM YLH + H L S+N D+ V+
Sbjct: 622 KGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGI-LHKDLKSKNVFYDNGKVV- 679
Query: 716 VTDYGLPALHRTQGLPPAQRTPRELL----W---TAPELIREA---REGGGWLATQSGDV 765
+TD+GL ++ G+ A R +L W APE+IR+ E ++ DV
Sbjct: 680 ITDFGLFSI---SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDV 736
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWS 825
F+ I E+ R P+ P E I + + ++P++S E ++ CW+
Sbjct: 737 FALGTIWYELHAREWPF---KTQPAEAI--IWQMGTGMKPNLSQIGMGKEISDILLFCWA 791
Query: 826 EAPDLRPDFNRLHDVFRQM-QRGRKIN 851
+ RP F +L D+ ++ +R R+++
Sbjct: 792 FEQEERPTFTKLMDMLEKLPKRNRRLS 818
>BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein.
Length = 827
Score = 66.5 bits (155), Expect = 6e-10
Identities = 72/267 (26%), Positives = 124/267 (46%), Gaps = 24/267 (8%)
Query: 598 RYKGD-AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDEC 655
R+ G+ A+ L ++ +LK +V+ Q R ENV F+G C+ A++ C
Sbjct: 561 RWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT-RHENVVLFMGACMSPPHLAIITSLC 619
Query: 656 WRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLR 715
+L V+ I LD + ++VKGM YLH + H L S+N D+ V+
Sbjct: 620 KGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGI-LHKDLKSKNVFYDNGKVV- 677
Query: 716 VTDYGLPALHRTQGLPPAQRTPRELL----W---TAPELIREA---REGGGWLATQSGDV 765
+TD+GL ++ G+ A R +L W APE+IR+ E ++ DV
Sbjct: 678 ITDFGLFSI---SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDV 734
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWS 825
F+ I E+ R P+ P E I + + ++P++S E ++ CW+
Sbjct: 735 FALGTIWYELHAREWPF---KTQPAEAI--IWQMGTGMKPNLSQIGMGKEISDILLFCWA 789
Query: 826 EAPDLRPDFNRLHDVFRQM-QRGRKIN 851
+ RP F +L D+ ++ +R R+++
Sbjct: 790 FEQEERPTFTKLMDMLEKLPKRNRRLS 816
>BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein.
Length = 827
Score = 66.5 bits (155), Expect = 6e-10
Identities = 72/267 (26%), Positives = 124/267 (46%), Gaps = 24/267 (8%)
Query: 598 RYKGD-AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDEC 655
R+ G+ A+ L ++ +LK +V+ Q R ENV F+G C+ A++ C
Sbjct: 561 RWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT-RHENVVLFMGACMSPPHLAIITSLC 619
Query: 656 WRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLR 715
+L V+ I LD + ++VKGM YLH + H L S+N D+ V+
Sbjct: 620 KGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGI-LHKDLKSKNVFYDNGKVV- 677
Query: 716 VTDYGLPALHRTQGLPPAQRTPRELL----W---TAPELIREA---REGGGWLATQSGDV 765
+TD+GL ++ G+ A R +L W APE+IR+ E ++ DV
Sbjct: 678 ITDFGLFSI---SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDV 734
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWS 825
F+ I E+ R P+ P E I + + ++P++S E ++ CW+
Sbjct: 735 FALGTIWYELHAREWPF---KTQPAEAI--IWQMGTGMKPNLSQIGMGKEISDILLFCWA 789
Query: 826 EAPDLRPDFNRLHDVFRQM-QRGRKIN 851
+ RP F +L D+ ++ +R R+++
Sbjct: 790 FEQEERPTFTKLMDMLEKLPKRNRRLS 816
>AY345972-1|AAQ24226.1| 829|Homo sapiens kinase suppressor of Ras-2
protein.
Length = 829
Score = 66.5 bits (155), Expect = 6e-10
Identities = 72/267 (26%), Positives = 124/267 (46%), Gaps = 24/267 (8%)
Query: 598 RYKGD-AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIG-CLCEGRPALVFDEC 655
R+ G+ A+ L ++ +LK +V+ Q R ENV F+G C+ A++ C
Sbjct: 563 RWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQT-RHENVVLFMGACMSPPHLAIITSLC 621
Query: 656 WRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLR 715
+L V+ I LD + ++VKGM YLH + H L S+N D+ V+
Sbjct: 622 KGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGI-LHKDLKSKNVFYDNGKVV- 679
Query: 716 VTDYGLPALHRTQGLPPAQRTPRELL----W---TAPELIREA---REGGGWLATQSGDV 765
+TD+GL ++ G+ A R +L W APE+IR+ E ++ DV
Sbjct: 680 ITDFGLFSI---SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDV 736
Query: 766 FSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWS 825
F+ I E+ R P+ P E I + + ++P++S E ++ CW+
Sbjct: 737 FALGTIWYELHAREWPF---KTQPAEAI--IWQMGTGMKPNLSQIGMGKEISDILLFCWA 791
Query: 826 EAPDLRPDFNRLHDVFRQM-QRGRKIN 851
+ RP F +L D+ ++ +R R+++
Sbjct: 792 FEQEERPTFTKLMDMLEKLPKRNRRLS 818
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 710
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 711 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 769
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 770 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 823
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 824 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 873
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 874 FGQIVNTLDKMIR 886
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 645 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 704
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 705 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 763
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 764 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 817
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 818 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 867
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 868 FGQIVNTLDKMIR 880
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 710
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 711 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 769
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 770 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 823
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 824 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 873
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 874 FGQIVNTLDKMIR 886
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 651 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 710
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 711 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 769
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 770 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 823
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 824 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 873
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 874 FGQIVNTLDKMIR 886
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 645 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 704
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 705 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 763
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 764 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 817
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 818 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 867
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 868 FGQIVNTLDKMIR 880
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 332
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 332
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 332
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 768
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 769 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 822
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 823 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 872
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 873 FGQIVNTLDKMIR 885
>AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein.
Length = 400
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 3 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 62
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 63 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 118
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 119 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 171
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 172 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 225
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 226 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 279
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 66.5 bits (155), Expect = 6e-10
Identities = 65/253 (25%), Positives = 112/253 (44%), Gaps = 27/253 (10%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 668 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 727
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 728 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 786
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 787 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 840
Query: 779 GE-PYCMLSFTPEEIIDKLCR----PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
GE PY T +++I+ + + PPP+ PS +M CW + + RP
Sbjct: 841 GERPY--WDMTNQDVINAIEQDYRLPPPMDCPSA--------LHQLMLDCWQKDRNHRPK 890
Query: 834 FNRLHDVFRQMQR 846
F ++ + +M R
Sbjct: 891 FGQIVNTLDKMIR 903
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 101 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 160
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 161 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 216
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 217 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 269
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 270 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 323
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 324 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 377
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 332
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 66.5 bits (155), Expect = 6e-10
Identities = 74/294 (25%), Positives = 131/294 (44%), Gaps = 43/294 (14%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDM-EKKKTEQLLNRMLP 894
+++ E L+K +L E+ ++ER +L M E+K TEQ +LP
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLP 332
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 66.1 bits (154), Expect = 7e-10
Identities = 54/213 (25%), Positives = 93/213 (43%), Gaps = 15/213 (7%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M L + G + +P + E G L + L + KL LS+ D+ +
Sbjct: 317 VMMKLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICE 376
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAP 745
GM YL + H L++RNC+V S +++++D+G+ + + W+ P
Sbjct: 377 GMEYLERNGY-IHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPP 435
Query: 746 ELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPPPLIR 804
E+ + + DV+SF ++M EV G+ P+ S ++++ + L R
Sbjct: 436 EVFLFNK------YSSKSDVWSFGVLMWEVFTEGKMPFENKSNL--QVVEAISEGFRLYR 487
Query: 805 PSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
P + AP VM CW E P+ RP F L
Sbjct: 488 PHL----APMSIYEVMYSCWHEKPEGRPTFAEL 516
>L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 1124
Score = 66.1 bits (154), Expect = 7e-10
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 16/183 (8%)
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
L +D+ +GM YL H L++RN +V +V ++ D+GL R
Sbjct: 942 LHFAADVARGMDYLSQKQF-IHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRL 1000
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFTPEEIIDK 795
P + W A E + + + T + DV+S+ +++ E++ + G PYC T E+ +K
Sbjct: 1001 P--VRWMAIESLNYS------VYTTNSDVWSYGVLLWEIVSLGGTPYC--GMTCAELYEK 1050
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
L + L +P E +MRQCW E P RP F ++ +M RK + +
Sbjct: 1051 LPQGYRLEKPL----NCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTT 1106
Query: 856 MFE 858
++E
Sbjct: 1107 LYE 1109
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 66.1 bits (154), Expect = 7e-10
Identities = 63/249 (25%), Positives = 109/249 (43%), Gaps = 19/249 (7%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 142 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 201
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 202 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 260
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 261 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 314
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I+ + + L P P +M CW + + RP F ++
Sbjct: 315 GERPY--WDMTNQDVINAIEQDYRLPPPM----DCPAALHQLMLDCWQKDRNHRPKFGQI 368
Query: 838 HDVFRQMQR 846
+ +M R
Sbjct: 369 VNTLDKMIR 377
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 66.1 bits (154), Expect = 7e-10
Identities = 63/249 (25%), Positives = 109/249 (43%), Gaps = 19/249 (7%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T + +R +M NV G + + P ++ E GSL+
Sbjct: 645 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 704
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 705 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLS 763
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 764 RFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMSY 817
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I+ + + L P P +M CW + + RP F ++
Sbjct: 818 GERPY--WDMTNQDVINAIEQDYRLPPPM----DCPAALHQLMLDCWQKDRNHRPKFGQI 871
Query: 838 HDVFRQMQR 846
+ +M R
Sbjct: 872 VNTLDKMIR 880
>BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 66.1 bits (154), Expect = 7e-10
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 16/183 (8%)
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
L +D+ +GM YL H L++RN +V +V ++ D+GL R
Sbjct: 942 LHFAADVARGMDYLSQKQF-IHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRL 1000
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFTPEEIIDK 795
P + W A E + + + T + DV+S+ +++ E++ + G PYC T E+ +K
Sbjct: 1001 P--VRWMAIESLNYS------VYTTNSDVWSYGVLLWEIVSLGGTPYC--GMTCAELYEK 1050
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
L + L +P E +MRQCW E P RP F ++ +M RK + +
Sbjct: 1051 LPQGYRLEKPL----NCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTT 1106
Query: 856 MFE 858
++E
Sbjct: 1107 LYE 1109
>AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase,
endothelial (venous malformations, multiple cutaneous and
protein.
Length = 1124
Score = 66.1 bits (154), Expect = 7e-10
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 16/183 (8%)
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
L +D+ +GM YL H L++RN +V +V ++ D+GL R
Sbjct: 942 LHFAADVARGMDYLSQKQF-IHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRL 1000
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFTPEEIIDK 795
P + W A E + + + T + DV+S+ +++ E++ + G PYC T E+ +K
Sbjct: 1001 P--VRWMAIESLNYS------VYTTNSDVWSYGVLLWEIVSLGGTPYC--GMTCAELYEK 1050
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
L + L +P E +MRQCW E P RP F ++ +M RK + +
Sbjct: 1051 LPQGYRLEKPL----NCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTT 1106
Query: 856 MFE 858
++E
Sbjct: 1107 LYE 1109
>AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase variant
protein.
Length = 1157
Score = 66.1 bits (154), Expect = 7e-10
Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 16/183 (8%)
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
L +D+ +GM YL H L++RN +V +V ++ D+GL R
Sbjct: 975 LHFAADVARGMDYLSQKQF-IHRDLAARNILVGENYVAKIADFGLSRGQEVYVKKTMGRL 1033
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFTPEEIIDK 795
P + W A E + + + T + DV+S+ +++ E++ + G PYC T E+ +K
Sbjct: 1034 P--VRWMAIESLNYS------VYTTNSDVWSYGVLLWEIVSLGGTPYC--GMTCAELYEK 1083
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGRKINIVDS 855
L + L +P E +MRQCW E P RP F ++ +M RK + +
Sbjct: 1084 LPQGYRLEKPL----NCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVNTT 1139
Query: 856 MFE 858
++E
Sbjct: 1140 LYE 1142
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/212 (25%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDE-CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKG 686
M L + F G + P + E G L + L + L+ + L + D+ +G
Sbjct: 464 MMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEG 523
Query: 687 MRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPE 746
M +L H L++RNC+VD ++V+D+G+ + T + W+APE
Sbjct: 524 MAFLESHQF-IHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPE 582
Query: 747 LIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDKLCRPPPLIRP 805
+ + + DV++F I+M EV G +PY + + +++ K+ + L RP
Sbjct: 583 VFHYFK------YSSKSDVWAFGILMWEVFSLGKQPYDL--YDNSQVVLKVSQGHRLYRP 634
Query: 806 SVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ A +M CW E P+ RP F +L
Sbjct: 635 HL----ASDTIYQIMYSCWHELPEKRPTFQQL 662
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 65.7 bits (153), Expect = 1e-09
Identities = 63/228 (27%), Positives = 100/228 (43%), Gaps = 25/228 (10%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M N+ G + + +P ++ E G+L+ L D + + +L +
Sbjct: 666 IMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAA 725
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPR----ELL 741
GM+YL H L++RN +V+S V +V+D+GL + + P A T +
Sbjct: 726 GMKYLANMNY-VHRDLAARNILVNSNLVCKVSDFGLSRV--LEDDPEATYTTSGGKIPIR 782
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLS--FTPEEIIDKLCR 798
WTAPE I + T + DV+SF I+M EV+ GE PY LS + I D
Sbjct: 783 WTAPEAISYRK------FTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRL 836
Query: 799 PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
P P+ PS +M QCW + RP F + + ++ R
Sbjct: 837 PTPMDCPSA--------IYQLMMQCWQQERARRPKFADIVSILDKLIR 876
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein.
Length = 347
Score = 65.7 bits (153), Expect = 1e-09
Identities = 59/226 (26%), Positives = 100/226 (44%), Gaps = 19/226 (8%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M NV G + + P ++ E GSL+ L +D + + +L +
Sbjct: 34 IMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAA 93
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPR----ELL 741
GM+YL H L++RN +V+S V +V+D+GL P + +
Sbjct: 94 GMKYLADMNY-VHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIR 152
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLSFTPEEIIDKLCRPP 800
WTAPE I+ + T + DV+S+ I+M EV+ GE PY T +++I+ + +
Sbjct: 153 WTAPEAIQYRK------FTSASDVWSYGIVMWEVMSYGERPY--WDMTNQDVINAIEQDY 204
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
L P P +M CW + + RP F ++ + +M R
Sbjct: 205 RLPPPM----DCPAALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIR 246
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 65.7 bits (153), Expect = 1e-09
Identities = 63/228 (27%), Positives = 100/228 (43%), Gaps = 25/228 (10%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M N+ G + + +P ++ E G+L+ L D + + +L +
Sbjct: 666 IMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAA 725
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPR----ELL 741
GM+YL H L++RN +V+S V +V+D+GL + + P A T +
Sbjct: 726 GMKYLANMNY-VHRDLAARNILVNSNLVCKVSDFGLSRV--LEDDPEATYTTSGGKIPIR 782
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLS--FTPEEIIDKLCR 798
WTAPE I + T + DV+SF I+M EV+ GE PY LS + I D
Sbjct: 783 WTAPEAISYRK------FTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRL 836
Query: 799 PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
P P+ PS +M QCW + RP F + + ++ R
Sbjct: 837 PTPMDCPSA--------IYQLMMQCWQQERARRPKFADIVSILDKLIR 876
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/212 (25%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDE-CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKG 686
M L + F G + P + E G L + L + L+ + L + D+ +G
Sbjct: 464 MMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEG 523
Query: 687 MRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPE 746
M +L H L++RNC+VD ++V+D+G+ + T + W+APE
Sbjct: 524 MAFLESHQF-IHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPE 582
Query: 747 LIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDKLCRPPPLIRP 805
+ + + DV++F I+M EV G +PY + + +++ K+ + L RP
Sbjct: 583 VFHYFK------YSSKSDVWAFGILMWEVFSLGKQPYDL--YDNSQVVLKVSQGHRLYRP 634
Query: 806 SVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ A +M CW E P+ RP F +L
Sbjct: 635 HL----ASDTIYQIMYSCWHELPEKRPTFQQL 662
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 65.7 bits (153), Expect = 1e-09
Identities = 63/228 (27%), Positives = 100/228 (43%), Gaps = 25/228 (10%)
Query: 627 LMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLEDVLMADDIKLDWTFRLSLLSDLVK 685
+M N+ G + + +P ++ E G+L+ L D + + +L +
Sbjct: 666 IMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAA 725
Query: 686 GMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPR----ELL 741
GM+YL H L++RN +V+S V +V+D+GL + + P A T +
Sbjct: 726 GMKYLANMNY-VHRDLAARNILVNSNLVCKVSDFGLSRV--LEDDPEATYTTSGGKIPIR 782
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGE-PYCMLS--FTPEEIIDKLCR 798
WTAPE I + T + DV+SF I+M EV+ GE PY LS + I D
Sbjct: 783 WTAPEAISYRK------FTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRL 836
Query: 799 PPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
P P+ PS +M QCW + RP F + + ++ R
Sbjct: 837 PTPMDCPSA--------IYQLMMQCWQQERARRPKFADIVSILDKLIR 876
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 661 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 720
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 721 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 779
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 780 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 831
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 832 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 885
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 886 IVGILDKMIR 895
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/213 (25%), Positives = 102/213 (47%), Gaps = 15/213 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGM 687
M+ ++ +++ G +C+ +V + GSLE VL L W R ++ + M
Sbjct: 75 MKKIKFQHIVSIYG-VCKQPLGIVMEFMANGSLEKVLSTHS--LCWKLRFRIIHETSLAM 131
Query: 688 RYLHG-SPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPRE--LLWT 743
+LH P H L N ++DS ++++D+GL + ++ + +R+ L +
Sbjct: 132 NFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYI 191
Query: 744 APELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCR-PPPL 802
PE+ E+ + G DV+SFAI++ E++ + +PY F II ++ P
Sbjct: 192 PPEMFLESNKAPG----PKYDVYSFAIVIWELLTQKKPYS--GFNMMMIIIRVAAGMRPS 245
Query: 803 IRP-SVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
++P S + + V +M++CW + P RP F
Sbjct: 246 LQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCF 278
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/213 (25%), Positives = 102/213 (47%), Gaps = 15/213 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGM 687
M+ ++ +++ G +C+ +V + GSLE VL L W R ++ + M
Sbjct: 75 MKKIKFQHIVSIYG-VCKQPLGIVMEFMANGSLEKVLSTHS--LCWKLRFRIIHETSLAM 131
Query: 688 RYLHG-SPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPRE--LLWT 743
+LH P H L N ++DS ++++D+GL + ++ + +R+ L +
Sbjct: 132 NFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYI 191
Query: 744 APELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCR-PPPL 802
PE+ E+ + G DV+SFAI++ E++ + +PY F II ++ P
Sbjct: 192 PPEMFLESNKAPG----PKYDVYSFAIVIWELLTQKKPYS--GFNMMMIIIRVAAGMRPS 245
Query: 803 IRP-SVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
++P S + + V +M++CW + P RP F
Sbjct: 246 LQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCF 278
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/213 (25%), Positives = 102/213 (47%), Gaps = 15/213 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGM 687
M+ ++ +++ G +C+ +V + GSLE VL L W R ++ + M
Sbjct: 75 MKKIKFQHIVSIYG-VCKQPLGIVMEFMANGSLEKVLSTHS--LCWKLRFRIIHETSLAM 131
Query: 688 RYLHG-SPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPRE--LLWT 743
+LH P H L N ++DS ++++D+GL + ++ + +R+ L +
Sbjct: 132 NFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYI 191
Query: 744 APELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCR-PPPL 802
PE+ E+ + G DV+SFAI++ E++ + +PY F II ++ P
Sbjct: 192 PPEMFLESNKAPG----PKYDVYSFAIVIWELLTQKKPYS--GFNMMMIIIRVAAGMRPS 245
Query: 803 IRP-SVSMGAAPPEAVSVMRQCWSEAPDLRPDF 834
++P S + + V +M++CW + P RP F
Sbjct: 246 LQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCF 278
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 65.7 bits (153), Expect = 1e-09
Identities = 54/212 (25%), Positives = 94/212 (44%), Gaps = 15/212 (7%)
Query: 628 MQNLRQENVNPFIGCLCEGRPALVFDE-CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKG 686
M L + F G + P + E G L + L + L+ + L + D+ +G
Sbjct: 486 MMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEG 545
Query: 687 MRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPE 746
M +L H L++RNC+VD ++V+D+G+ + T + W+APE
Sbjct: 546 MAFLESHQF-IHRDLAARNCLVDRDLCVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPE 604
Query: 747 LIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDKLCRPPPLIRP 805
+ + + DV++F I+M EV G +PY + + +++ K+ + L RP
Sbjct: 605 VFHYFK------YSSKSDVWAFGILMWEVFSLGKQPYDL--YDNSQVVLKVSQGHRLYRP 656
Query: 806 SVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ A +M CW E P+ RP F +L
Sbjct: 657 HL----ASDTIYQIMYSCWHELPEKRPTFQQL 684
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 65.7 bits (153), Expect = 1e-09
Identities = 68/250 (27%), Positives = 112/250 (44%), Gaps = 21/250 (8%)
Query: 603 AVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLE 661
AV ++ L+V T + +R +M NV G + G+P ++ E G+L+
Sbjct: 663 AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD 722
Query: 662 DVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGL 721
L D + + +L + GMRYL H L++RN +V+S V +V+D+GL
Sbjct: 723 AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGY-VHRDLAARNILVNSNLVCKVSDFGL 781
Query: 722 PALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIV 777
+ + P A T + WTAPE I+ + T + DV+S+ I+M EV+
Sbjct: 782 SRV--IEDDPEAVYTTTGGKIPVRWTAPEAIQYRK------FTSASDVWSYGIVMWEVMS 833
Query: 778 RGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNR 836
GE PY +S +++I + L P P +M CW + RP F +
Sbjct: 834 YGERPYWDMS--NQDVIKAIEEGYRLPAPM----DCPAGLHQLMLDCWQKERAERPKFEQ 887
Query: 837 LHDVFRQMQR 846
+ + +M R
Sbjct: 888 IVGILDKMIR 897
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 65.3 bits (152), Expect = 1e-09
Identities = 62/249 (24%), Positives = 110/249 (44%), Gaps = 19/249 (7%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG-SLED 662
V ++ L+V T +R +M N+ G + + RP ++ E +L+
Sbjct: 662 VAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDS 721
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 722 FLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNY-VHRDLAARNILVNSNLVCKVSDFGLS 780
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRK------FTSASDVWSYGIVMWEVMSY 834
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY +S +++I+ + + L P P +M CW +LRP F+++
Sbjct: 835 GERPYWDMS--NQDVINAVEQDYRLPPPM----DCPTALHQLMLDCWVRDRNLRPKFSQI 888
Query: 838 HDVFRQMQR 846
+ ++ R
Sbjct: 889 VNTLDKLIR 897
>BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein
protein.
Length = 969
Score = 65.3 bits (152), Expect = 1e-09
Identities = 63/249 (25%), Positives = 111/249 (44%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+V T + +R +M N+ G + + +P ++ E GSL+
Sbjct: 636 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 695
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +++S V +V+D+ L
Sbjct: 696 FLKKNDGQFTVIQLVGMLRGISAGMKYLSDMGY-VHRDLAARNILINSNLVCKVSDFELS 754
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ P A T R + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 755 RVLEDD--PEAAYTTRGGKIPIRWTAPEAIAFRK------FTSASDVWSYGIVMWEVVSY 806
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY T +++I + L P P +M CW + + RP F+ +
Sbjct: 807 GERPY--WEMTNQDVIKAVEEGYRLPSPM----DCPAALYQLMLDCWQKERNSRPKFDEI 860
Query: 838 HDVFRQMQR 846
++ ++ R
Sbjct: 861 VNMLDKLIR 869
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 65.3 bits (152), Expect = 1e-09
Identities = 62/249 (24%), Positives = 110/249 (44%), Gaps = 19/249 (7%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRG-SLED 662
V ++ L+V T +R +M N+ G + + RP ++ E +L+
Sbjct: 662 VAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDS 721
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L +D + + +L + GM+YL H L++RN +V+S V +V+D+GL
Sbjct: 722 FLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNY-VHRDLAARNILVNSNLVCKVSDFGLS 780
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
P + + WTAPE I + T + DV+S+ I+M EV+
Sbjct: 781 RFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRK------FTSASDVWSYGIVMWEVMSY 834
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY +S +++I+ + + L P P +M CW +LRP F+++
Sbjct: 835 GERPYWDMS--NQDVINAVEQDYRLPPPM----DCPTALHQLMLDCWVRDRNLRPKFSQI 888
Query: 838 HDVFRQMQR 846
+ ++ R
Sbjct: 889 VNTLDKLIR 897
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 64.9 bits (151), Expect = 2e-09
Identities = 77/319 (24%), Positives = 138/319 (43%), Gaps = 42/319 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDMEKKKTEQLLNRMLPRSVAERL 901
+++ E L+K +L E+ ++ER +L M ++K + N L +A R+
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARM 338
Query: 902 MLGSRVEPEEFEEVSIYFS 920
S E + E S S
Sbjct: 339 SEESYFESKTEESNSAEMS 357
>AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein.
Length = 1005
Score = 64.9 bits (151), Expect = 2e-09
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T +R +M N+ G + GR A++ E GSL+
Sbjct: 664 VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDT 723
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L D + + +L + GMRYL H L++RN +VDS V +V+D+GL
Sbjct: 724 FLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGY-VHRDLAARNVLVDSNLVCKVSDFGLS 782
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ + P A T + WTAPE I + + DV+SF ++M EV+
Sbjct: 783 RV--LEDDPDAAYTTTGGKIPIRWTAPEAIAFR------TFSSASDVWSFGVVMWEVLAY 834
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY + T ++I + L P MG P +M CW + RP F+++
Sbjct: 835 GERPY--WNMTNRDVISSVEEGYRLPAP---MG-CPHALHQLMLDCWHKDRAQRPRFSQI 888
Query: 838 HDVFRQMQR 846
V + R
Sbjct: 889 VSVLDALIR 897
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 64.9 bits (151), Expect = 2e-09
Identities = 77/319 (24%), Positives = 138/319 (43%), Gaps = 42/319 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDMEKKKTEQLLNRMLPRSVAERL 901
+++ E L+K +L E+ ++ER +L M ++K + N L +A R+
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARM 338
Query: 902 MLGSRVEPEEFEEVSIYFS 920
S E + E S S
Sbjct: 339 SEESYFESKTEESNSAEMS 357
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 64.9 bits (151), Expect = 2e-09
Identities = 77/319 (24%), Positives = 138/319 (43%), Gaps = 42/319 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDMEKKKTEQLLNRMLPRSVAERL 901
+++ E L+K +L E+ ++ER +L M ++K + N L +A R+
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARM 338
Query: 902 MLGSRVEPEEFEEVSIYFS 920
S E + E S S
Sbjct: 339 SEESYFESKTEESNSAEMS 357
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 64.9 bits (151), Expect = 2e-09
Identities = 77/319 (24%), Positives = 138/319 (43%), Gaps = 42/319 (13%)
Query: 627 LMQNLRQENVNPFIGCLCEG-RPALVFDECWRGSLEDVLMAD-DIKLDWTFRLSLLSDLV 684
++ L N+ F G + E +V + GSL D + ++ ++D ++ +D+
Sbjct: 56 ILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVA 115
Query: 685 KGMRYLH-GSPLRA-HGRLSSRNCVVDSRWVLRVTDYGLPALH-RTQGLPPAQRTPRELL 741
KGM YLH +P++ H L SRN V+ + VL++ D+G H T + P
Sbjct: 116 KGMHYLHMEAPVKVIHRDLKSRNVVIAADGVLKICDFGASRFHNHTTHMSLVGTFP---- 171
Query: 742 WTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEE--IIDKLCRP 799
W APE+I+ +++ D +S+ +++ E++ R P+ L +++K R
Sbjct: 172 WMAPEVIQSLP------VSETCDTYSYGVVLWEMLTREVPFKGLEGLQVAWLVVEKNER- 224
Query: 800 PPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQRGR----KINI--- 852
L PS + P ++ QCW RP F ++ + M K N
Sbjct: 225 --LTIPS----SCPRSFAELLHQCWEADAKKRPSFKQIISILESMSNDTSLPDKCNSFLH 278
Query: 853 --------VDSMFEMLEKYSNNL---EELIRERTEQLDMEKKKTEQLLNRMLPRSVAERL 901
+++ E L+K +L E+ ++ER +L M ++K + N L +A R+
Sbjct: 279 NKAEWRCEIEATLERLKKLERDLSFKEQELKERERRLKMWEQKLTEQSNTPLLLPLAARM 338
Query: 902 MLGSRVEPEEFEEVSIYFS 920
S E + E S S
Sbjct: 339 SEESYFESKTEESNSAEMS 357
>AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein.
Length = 853
Score = 64.9 bits (151), Expect = 2e-09
Identities = 69/249 (27%), Positives = 108/249 (43%), Gaps = 21/249 (8%)
Query: 604 VHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-GSLED 662
V ++ L+ T +R +M N+ G + GR A++ E GSL+
Sbjct: 512 VAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDT 571
Query: 663 VLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP 722
L D + + +L + GMRYL H L++RN +VDS V +V+D+GL
Sbjct: 572 FLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGY-VHRDLAARNVLVDSNLVCKVSDFGLS 630
Query: 723 ALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVR 778
+ + P A T + WTAPE I + + DV+SF ++M EV+
Sbjct: 631 RV--LEDDPDAAYTTTGGKIPIRWTAPEAIAFR------TFSSASDVWSFGVVMWEVLAY 682
Query: 779 GE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
GE PY + T ++I + L P MG P +M CW + RP F+++
Sbjct: 683 GERPY--WNMTNRDVISSVEEGYRLPAP---MG-CPHALHQLMLDCWHKDRAQRPRFSQI 736
Query: 838 HDVFRQMQR 846
V + R
Sbjct: 737 VSVLDALIR 745
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 64.5 bits (150), Expect = 2e-09
Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIG-CL-CEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
++M++ NV +G CL EG P +V G L + + + + +
Sbjct: 1129 IIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQV 1188
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPREL-- 740
KGM+YL S H L++RNC++D ++ ++V D+GL ++ + +T +L
Sbjct: 1189 AKGMKYL-ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPV 1247
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ + T DV+SF +++ E++ RG P +I L +
Sbjct: 1248 KWMALESLQTQK------FTTKSDVWSFGVVLWELMTRGAP-PYPDVNTFDITVYLLQGR 1300
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L++P P VM +CW ++RP F+ L
Sbjct: 1301 RLLQPEY----CPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 584 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 642
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 643 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 695
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 696 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 739
>AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth factor
receptor 4 variant protein.
Length = 592
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 374 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 432
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 433 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 485
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 486 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 529
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 544 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 602
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 603 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 655
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 656 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 699
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/169 (28%), Positives = 76/169 (44%), Gaps = 15/169 (8%)
Query: 671 LDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLP-ALHRTQG 729
L + +S + +GM+YL H L++RN +V V+++ D+GL +H
Sbjct: 816 LSFPVLVSCAYQVARGMQYLESRKC-IHRDLAARNVLVTEDNVMKIADFGLARGVHHIDY 874
Query: 730 LPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVI-VRGEPYCMLSFT 788
+ W APE + + + T DV+SF I++ E+ + G PY +
Sbjct: 875 YKKTSNGRLPVKWMAPEALFDR------VYTHQSDVWSFGILLWEIFTLGGSPYPGIPV- 927
Query: 789 PEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
EE+ L + RP PPE +MR+CW AP RP F +L
Sbjct: 928 -EELFSLLREGHRMDRPP----HCPPELYGLMRECWHAAPSQRPTFKQL 971
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIG-CL-CEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
++M++ NV +G CL EG P +V G L + + + + +
Sbjct: 262 IIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQV 321
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPREL-- 740
KGM+YL S H L++RNC++D ++ ++V D+GL ++ + +T +L
Sbjct: 322 AKGMKYL-ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPV 380
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ + T DV+SF +++ E++ RG P +I L +
Sbjct: 381 KWMALESLQTQK------FTTKSDVWSFGVLLWELMTRGAP-PYPDVNTFDITVYLLQGR 433
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L++P P VM +CW ++RP F+ L
Sbjct: 434 RLLQPEY----CPDPLYEVMLKCWHPKAEMRPSFSEL 466
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIG-CL-CEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
++M++ NV +G CL EG P +V G L + + + + +
Sbjct: 194 IIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQV 253
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPREL-- 740
KGM+YL S H L++RNC++D ++ ++V D+GL ++ + +T +L
Sbjct: 254 AKGMKYL-ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPV 312
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ + T DV+SF +++ E++ RG P +I L +
Sbjct: 313 KWMALESLQTQK------FTTKSDVWSFGVLLWELMTRGAP-PYPDVNTFDITVYLLQGR 365
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L++P P VM +CW ++RP F+ L
Sbjct: 366 RLLQPEY----CPDPLYEVMLKCWHPKAEMRPSFSEL 398
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 640 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 699
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 700 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 758
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 812
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 813 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 866
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 867 FPQVVSALDKMIR 879
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 64.1 bits (149), Expect = 3e-09
Identities = 61/255 (23%), Positives = 118/255 (46%), Gaps = 12/255 (4%)
Query: 596 RIRYKGDAVHLRHLQVTG-TLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDE 654
R R+ GD V ++ L+V+ T E + + + +++ R N+ PF+G + A++
Sbjct: 35 RGRWHGD-VAVKVLKVSQPTAEQAQAFKNEMQVLRKTRHVNILPFMGFMTRPGVAIITQW 93
Query: 655 CWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVL 714
C SL L D + D + + +GM YLH + H L S N + +
Sbjct: 94 CEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNI-IHRDLKSNNIFLHEGLTV 152
Query: 715 RVTDYGLPALH-RTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQ 773
++ D+GL + R G P ++ +LW A E+ R + + QS DV+++ +++
Sbjct: 153 KIGDFGLATVKTRWSGAQPLEQPSGPVLWMAAEVTR--MQDPNPYSFQS-DVYAYGVVLY 209
Query: 774 EVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVS-MGAAPPEAV-SVMRQCWSEAPDLR 831
E++ PY + ++II + R + P +S + + P+A+ ++ C + R
Sbjct: 210 ELMTGSLPYSHIG-CRDQIIFMVGR--GYLSPDLSKISSNCPKAMRRLLSDCLKFQREER 266
Query: 832 PDFNRLHDVFRQMQR 846
P F ++ +QR
Sbjct: 267 PLFPQILATIELLQR 281
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIG-CL-CEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
++M++ NV +G CL EG P +V G L + + + + +
Sbjct: 1129 IIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQV 1188
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPREL-- 740
KGM+YL S H L++RNC++D ++ ++V D+GL ++ + +T +L
Sbjct: 1189 AKGMKYL-ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPV 1247
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ + T DV+SF +++ E++ RG P +I L +
Sbjct: 1248 KWMALESLQTQK------FTTKSDVWSFGVLLWELMTRGAP-PYPDVNTFDITVYLLQGR 1300
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L++P P VM +CW ++RP F+ L
Sbjct: 1301 RLLQPEY----CPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 64.1 bits (149), Expect = 3e-09
Identities = 65/258 (25%), Positives = 116/258 (44%), Gaps = 24/258 (9%)
Query: 596 RIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEG-RPA-LVFD 653
R Y+G+ V ++ +L L R+ L+++ +L ++ I L G RP LV +
Sbjct: 1895 RAAYEGEEVAVKIFNKHTSLRLLRQE---LVVLCHLHHPSL---ISLLAAGIRPRMLVME 1948
Query: 654 ECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVV----- 708
+GSL+ +L D L T + + + G+RYLH S + + L N ++
Sbjct: 1949 LASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLH-SAMIIYRDLKPHNVLLFTLYP 2007
Query: 709 DSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSF 768
++ + ++ DYG+ G+ ++ TP + APE+ R G + Q DV+SF
Sbjct: 2008 NAAIIAKIADYGIAQYCCRMGIKTSEGTPG---FRAPEVAR-----GNVIYNQQADVYSF 2059
Query: 769 AIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAP-PEAVSVMRQCWSEA 827
+++ +++ G P E D+L L P G AP P +++QC E
Sbjct: 2060 GLLLYDILTTGGRIVEGLKFPNE-FDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKEN 2118
Query: 828 PDLRPDFNRLHDVFRQMQ 845
P RP ++ D+ +
Sbjct: 2119 PQERPTSAQVFDILNSAE 2136
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 640 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 699
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 700 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 758
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 812
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 813 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 866
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 867 FPQVVSALDKMIR 879
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 498 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 557
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 558 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 616
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 617 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 670
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 671 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 724
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 725 FPQVVSALDKMIR 737
>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 64.1 bits (149), Expect = 3e-09
Identities = 65/258 (25%), Positives = 116/258 (44%), Gaps = 24/258 (9%)
Query: 596 RIRYKGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEG-RPA-LVFD 653
R Y+G+ V ++ +L L R+ L+++ +L ++ I L G RP LV +
Sbjct: 1895 RAAYEGEEVAVKIFNKHTSLRLLRQE---LVVLCHLHHPSL---ISLLAAGIRPRMLVME 1948
Query: 654 ECWRGSLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVV----- 708
+GSL+ +L D L T + + + G+RYLH S + + L N ++
Sbjct: 1949 LASKGSLDRLLQQDKASLTRTLQHRIALHVADGLRYLH-SAMIIYRDLKPHNVLLFTLYP 2007
Query: 709 DSRWVLRVTDYGLPALHRTQGLPPAQRTPRELLWTAPELIREAREGGGWLATQSGDVFSF 768
++ + ++ DYG+ G+ ++ TP + APE+ R G + Q DV+SF
Sbjct: 2008 NAAIIAKIADYGIAQYCCRMGIKTSEGTPG---FRAPEVAR-----GNVIYNQQADVYSF 2059
Query: 769 AIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAP-PEAVSVMRQCWSEA 827
+++ +++ G P E D+L L P G AP P +++QC E
Sbjct: 2060 GLLLYDILTTGGRIVEGLKFPNE-FDELEIQGKLPDPVKEYGCAPWPMVEKLIKQCLKEN 2118
Query: 828 PDLRPDFNRLHDVFRQMQ 845
P RP ++ D+ +
Sbjct: 2119 PQERPTSAQVFDILNSAE 2136
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 640 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 699
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 700 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 758
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 812
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 813 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 866
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 867 FPQVVSALDKMIR 879
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 640 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 699
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 700 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 758
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 812
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 813 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 866
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 867 FPQVVSALDKMIR 879
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 640 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 699
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 700 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 758
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 759 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 812
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 813 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 866
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 867 FPQVVSALDKMIR 879
>AB231718-1|BAE46879.1| 54|Homo sapiens hypothetical protein
protein.
Length = 54
Score = 64.1 bits (149), Expect = 3e-09
Identities = 28/54 (51%), Positives = 45/54 (83%)
Query: 863 YSNNLEELIRERTEQLDMEKKKTEQLLNRMLPRSVAERLMLGSRVEPEEFEEVS 916
YS NLE+LI+E+TE+L+++++KTE+LL +M+P SVAE +G+ VEP F++V+
Sbjct: 1 YSQNLEDLIQEQTEELELKREKTERLLCQMIPPSVAEARKMGATVEPGYFDQVT 54
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene
precursor variant protein.
Length = 712
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/217 (25%), Positives = 98/217 (45%), Gaps = 17/217 (7%)
Query: 626 LLMQNLRQENVNPFIG-CL-CEGRPALVFDECWRGSLEDVLMADDIKLDWTFRLSLLSDL 683
++M++ NV +G CL EG P +V G L + + + + +
Sbjct: 451 IIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQV 510
Query: 684 VKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPA-LHRTQGLPPAQRTPREL-- 740
KGM+YL S H L++RNC++D ++ ++V D+GL ++ + +T +L
Sbjct: 511 AKGMKYL-ASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPV 569
Query: 741 LWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRGEPYCMLSFTPEEIIDKLCRPP 800
W A E ++ + T DV+SF +++ E++ RG P +I L +
Sbjct: 570 KWMALESLQTQK------FTTKSDVWSFGVLLWELMTRGAP-PYPDVNTFDITVYLLQGR 622
Query: 801 PLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
L++P P VM +CW ++RP F+ L
Sbjct: 623 RLLQPEY----CPDPLYEVMLKCWHPKAEMRPSFSEL 655
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 64.1 bits (149), Expect = 3e-09
Identities = 62/253 (24%), Positives = 107/253 (42%), Gaps = 19/253 (7%)
Query: 600 KGDAVHLRHLQVTGTLELKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWR-G 658
K V ++ L+ T +R+ +M N+ G + P ++ E G
Sbjct: 639 KESCVAIKTLKGGYTERQRREFLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENG 698
Query: 659 SLEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTD 718
+L+ L +D + + +L + GMRYL H L++RN +V+S V +V+D
Sbjct: 699 ALDSFLRLNDGQFTVIQLVGMLRGIASGMRYL-AEMSYVHRDLAARNILVNSNLVCKVSD 757
Query: 719 YGLPALHRTQGLPPAQRTPR----ELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQE 774
+GL P + + WTAPE I + T + D +S+ I+M E
Sbjct: 758 FGLSRFLEENSSDPTYTSSLGGKIPIRWTAPEAIAFRK------FTSASDAWSYGIVMWE 811
Query: 775 VIVRGE-PYCMLSFTPEEIIDKLCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPD 833
V+ GE PY +S +++I+ + + L P P +M CW + + RP
Sbjct: 812 VMSFGERPYWDMS--NQDVINAIEQDYRLPPPP----DCPTSLHQLMLDCWQKDRNARPR 865
Query: 834 FNRLHDVFRQMQR 846
F ++ +M R
Sbjct: 866 FPQVVSALDKMIR 878
>M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene
protein.
Length = 211
Score = 63.7 bits (148), Expect = 4e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 20/217 (9%)
Query: 635 NVNPFIGCLCEGRPALVFDECWRGS-LEDVLMADDIKLDWTFRLSLLSDLVKGMRYLHGS 693
N+ IG + +P + E +G L + +L L ++ D GM YL S
Sbjct: 7 NIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLE-S 65
Query: 694 PLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRTPRE--LLWTAPELIREA 751
H L++RNC+V + VL+++D+G+ + + A R+ + WTAPE +
Sbjct: 66 KCCIHRDLAARNCLVTEKNVLKISDFGM-SRDEADRVYAASGGLRQVPVKWTAPEALNYG 124
Query: 752 REGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLS-FTPEEIIDKLCRPPPLIRPSVSM 809
R + DV SF I++ E G PY LS E ++K R P P +
Sbjct: 125 R------YSSESDVSSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLP---CPEL-- 173
Query: 810 GAAPPEAVSVMRQCWSEAPDLRPDFNRLHDVFRQMQR 846
P +M QCW+ P RP F+ ++ + +++
Sbjct: 174 --CPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRK 208
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase
protein.
Length = 1052
Score = 63.7 bits (148), Expect = 4e-09
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 617 LKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFR 676
++ K L M+ ++ IG + E ++ + C G L L LD
Sbjct: 464 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 523
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
+ L + YL H +++RN +V S +++ D+GL A +
Sbjct: 524 ILYAYQLSTALAYLESKRF-VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 582
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDK 795
+ W APE I R T + DV+ F + M E+++ G +P+ ++I +
Sbjct: 583 KLPIKWMAPESINFRR------FTSASDVWMFGVCMWEILMHGVKPF--QGVKNNDVIGR 634
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ L P PP S+M +CW+ P RP F L
Sbjct: 635 IENGERLPMPP----NCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 63.7 bits (148), Expect = 4e-09
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 617 LKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFR 676
++ K L M+ ++ IG + E ++ + C G L L LD
Sbjct: 464 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 523
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
+ L + YL H +++RN +V S +++ D+GL A +
Sbjct: 524 ILYAYQLSTALAYLESKRF-VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 582
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDK 795
+ W APE I R T + DV+ F + M E+++ G +P+ ++I +
Sbjct: 583 KLPIKWMAPESINFRR------FTSASDVWMFGVCMWEILMHGVKPF--QGVKNNDVIGR 634
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ L P PP S+M +CW+ P RP F L
Sbjct: 635 IENGERLPMPP----NCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 63.7 bits (148), Expect = 4e-09
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 14/222 (6%)
Query: 617 LKRKSTDVLLLMQNLRQENVNPFIGCLCEGRPALVFDECWRGSLEDVLMADDIKLDWTFR 676
++ K L M+ ++ IG + E ++ + C G L L LD
Sbjct: 92 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 151
Query: 677 LSLLSDLVKGMRYLHGSPLRAHGRLSSRNCVVDSRWVLRVTDYGLPALHRTQGLPPAQRT 736
+ L + YL H +++RN +V S +++ D+GL A +
Sbjct: 152 ILYAYQLSTALAYLESKRF-VHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKG 210
Query: 737 PRELLWTAPELIREAREGGGWLATQSGDVFSFAIIMQEVIVRG-EPYCMLSFTPEEIIDK 795
+ W APE I R T + DV+ F + M E+++ G +P+ ++I +
Sbjct: 211 KLPIKWMAPESINFRR------FTSASDVWMFGVCMWEILMHGVKPF--QGVKNNDVIGR 262
Query: 796 LCRPPPLIRPSVSMGAAPPEAVSVMRQCWSEAPDLRPDFNRL 837
+ L P PP S+M +CW+ P RP F L
Sbjct: 263 IENGERLPMPP----NCPPTLYSLMTKCWAYDPSRRPRFTEL 300
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.402
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 164,583,297
Number of Sequences: 224733
Number of extensions: 6646220
Number of successful extensions: 24967
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 873
Number of HSP's that attempted gapping in prelim test: 23371
Number of HSP's gapped (non-prelim): 1369
length of query: 1244
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1146
effective length of database: 51,211,004
effective search space: 58687810584
effective search space used: 58687810584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
- SilkBase 1999-2023 -